Guide to the Human Genome
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Search of human proteins with 111955326

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|111955326 MLX interacting protein [Homo sapiens]
         (919 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|111955326 MLX interacting protein [Homo sapiens]                  1883   0.0  
gi|14602437 Williams Beuren syndrome chromosome region 14 isofor...   551   e-156
gi|14602433 Williams Beuren syndrome chromosome region 14 isofor...   549   e-156
gi|14602439 Williams Beuren syndrome chromosome region 14 isofor...   525   e-149
gi|14602435 Williams Beuren syndrome chromosome region 14 isofor...   523   e-148
gi|38201614 transcription factor-like protein 4 isoform alpha [H...    87   9e-17
gi|38201612 transcription factor-like protein 4 isoform beta [Ho...    87   9e-17
gi|24586667 transcription factor-like protein 4 isoform gamma [H...    87   9e-17
gi|163965366 nascent polypeptide-associated complex alpha subuni...    72   2e-12
gi|116284392 mucin 2 precursor [Homo sapiens]                          69   2e-11
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         67   1e-10
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             65   3e-10
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   64   8e-10
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   64   8e-10
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   64   8e-10
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    64   8e-10
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    63   1e-09
gi|47132519 Ras association and pleckstrin homology domains 1 is...    63   1e-09
gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi...    62   2e-09
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]               62   3e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    61   4e-09
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]               61   4e-09
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ...    61   5e-09
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [...    61   5e-09
gi|237757326 synaptojanin 1 isoform d [Homo sapiens]                   60   7e-09
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    60   9e-09
gi|146134388 YLP motif containing 1 [Homo sapiens]                     59   2e-08
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]                    59   2e-08
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                59   3e-08
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                59   3e-08

>gi|111955326 MLX interacting protein [Homo sapiens]
          Length = 919

 Score = 1883 bits (4878), Expect = 0.0
 Identities = 919/919 (100%), Positives = 919/919 (100%)

Query: 1   MAADVFMCSPRRPRSRGRQVLLKPQVSEDDDDSDTDEPSPPPASGAATPARAHASAAPPP 60
           MAADVFMCSPRRPRSRGRQVLLKPQVSEDDDDSDTDEPSPPPASGAATPARAHASAAPPP
Sbjct: 1   MAADVFMCSPRRPRSRGRQVLLKPQVSEDDDDSDTDEPSPPPASGAATPARAHASAAPPP 60

Query: 61  PRAGPGREEPPRRQQIIHSGHFMVSSPHREHPPKKGYDFDTVNKQTCQTYSFGKTSSCHL 120
           PRAGPGREEPPRRQQIIHSGHFMVSSPHREHPPKKGYDFDTVNKQTCQTYSFGKTSSCHL
Sbjct: 61  PRAGPGREEPPRRQQIIHSGHFMVSSPHREHPPKKGYDFDTVNKQTCQTYSFGKTSSCHL 120

Query: 121 SIDASLTKLFECMTLAYSGKLVSPKWKNFKGLKLQWRDKIRLNNAIWRAWYMQYLEKRKN 180
           SIDASLTKLFECMTLAYSGKLVSPKWKNFKGLKLQWRDKIRLNNAIWRAWYMQYLEKRKN
Sbjct: 121 SIDASLTKLFECMTLAYSGKLVSPKWKNFKGLKLQWRDKIRLNNAIWRAWYMQYLEKRKN 180

Query: 181 PVCHFVTPLDGSVDVDEHRRPEAITTEGKYWKSRIEIVIREYHKWRTYFKKRLQQHKDED 240
           PVCHFVTPLDGSVDVDEHRRPEAITTEGKYWKSRIEIVIREYHKWRTYFKKRLQQHKDED
Sbjct: 181 PVCHFVTPLDGSVDVDEHRRPEAITTEGKYWKSRIEIVIREYHKWRTYFKKRLQQHKDED 240

Query: 241 LSSLVQDDDMLYWHKHGDGWKTPVPMEEDPLLDTDMLMSEFSDTLFSTLSSHQPVAWPNP 300
           LSSLVQDDDMLYWHKHGDGWKTPVPMEEDPLLDTDMLMSEFSDTLFSTLSSHQPVAWPNP
Sbjct: 241 LSSLVQDDDMLYWHKHGDGWKTPVPMEEDPLLDTDMLMSEFSDTLFSTLSSHQPVAWPNP 300

Query: 301 REIAHLGNADMIQPGLIPLQPNLDFMDTFEPFQDLFSSSRSIFGSMLPASASAPVPDPNN 360
           REIAHLGNADMIQPGLIPLQPNLDFMDTFEPFQDLFSSSRSIFGSMLPASASAPVPDPNN
Sbjct: 301 REIAHLGNADMIQPGLIPLQPNLDFMDTFEPFQDLFSSSRSIFGSMLPASASAPVPDPNN 360

Query: 361 PPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQPTDFGPSEP 420
           PPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQPTDFGPSEP
Sbjct: 361 PPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQPTDFGPSEP 420

Query: 421 PLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTFHQPQKFAGVNKA 480
           PLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTFHQPQKFAGVNKA
Sbjct: 421 PLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTFHQPQKFAGVNKA 480

Query: 481 PSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPVTRPPQPRLTFVH 540
           PSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPVTRPPQPRLTFVH
Sbjct: 481 PSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPVTRPPQPRLTFVH 540

Query: 541 PKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAAFSGQPQAVIMTSGPLKREGML 600
           PKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAAFSGQPQAVIMTSGPLKREGML
Sbjct: 541 PKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAAFSGQPQAVIMTSGPLKREGML 600

Query: 601 ASTVSQSNVVIAPAAIARAPGVPEFHSSILVTDLGHGTSSPPAPVSRLFPSTAQDPLGKG 660
           ASTVSQSNVVIAPAAIARAPGVPEFHSSILVTDLGHGTSSPPAPVSRLFPSTAQDPLGKG
Sbjct: 601 ASTVSQSNVVIAPAAIARAPGVPEFHSSILVTDLGHGTSSPPAPVSRLFPSTAQDPLGKG 660

Query: 661 EQVPLHGGSPQVTVTGPSRDCPNSGQASPCASEQSPSPQSPQNNCSGKSDPKNVAALKNR 720
           EQVPLHGGSPQVTVTGPSRDCPNSGQASPCASEQSPSPQSPQNNCSGKSDPKNVAALKNR
Sbjct: 661 EQVPLHGGSPQVTVTGPSRDCPNSGQASPCASEQSPSPQSPQNNCSGKSDPKNVAALKNR 720

Query: 721 QMKHISAEQKRRFNIKMCFDMLNSLISNNSKLTSHAITLQKTVEYITKLQQERGQMQEEA 780
           QMKHISAEQKRRFNIKMCFDMLNSLISNNSKLTSHAITLQKTVEYITKLQQERGQMQEEA
Sbjct: 721 QMKHISAEQKRRFNIKMCFDMLNSLISNNSKLTSHAITLQKTVEYITKLQQERGQMQEEA 780

Query: 781 RRLREEIEELNATIISCQQLLPATGVPVTRRQFDHMKDMFDEYVKTRTLQNWKFWIFSII 840
           RRLREEIEELNATIISCQQLLPATGVPVTRRQFDHMKDMFDEYVKTRTLQNWKFWIFSII
Sbjct: 781 RRLREEIEELNATIISCQQLLPATGVPVTRRQFDHMKDMFDEYVKTRTLQNWKFWIFSII 840

Query: 841 IKPLFESFKGMVSTSSLEELHRTALSWLDQHCSLPILRPMVLSTLRQLSTSTSILTDPAQ 900
           IKPLFESFKGMVSTSSLEELHRTALSWLDQHCSLPILRPMVLSTLRQLSTSTSILTDPAQ
Sbjct: 841 IKPLFESFKGMVSTSSLEELHRTALSWLDQHCSLPILRPMVLSTLRQLSTSTSILTDPAQ 900

Query: 901 LPEQASKAVTRIGKRLGES 919
           LPEQASKAVTRIGKRLGES
Sbjct: 901 LPEQASKAVTRIGKRLGES 919


>gi|14602437 Williams Beuren syndrome chromosome region 14 isoform
           gamma [Homo sapiens]
          Length = 850

 Score =  551 bits (1419), Expect = e-156
 Identities = 385/944 (40%), Positives = 502/944 (53%), Gaps = 148/944 (15%)

Query: 17  GRQVLLKPQVSEDDDDSDTDEPSPPPASGAATPARAHASAAPPPPRAGPGREEPPRRQQI 76
           G QV       + D D+D+++PS   ++G                           R Q+
Sbjct: 11  GLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLL------------------------RSQV 46

Query: 77  IHSGHFMVSSPHREHPPKKGYDFDTVNKQTCQTYSFGKTSSCHLSIDASLTKLFECMTLA 136
           IHSGHFMVSSPH +  P++            Q  S G +     SID +LT+LFEC++LA
Sbjct: 47  IHSGHFMVSSPHSDSLPRR----------RDQEGSVGPSDFGPRSIDPTLTRLFECLSLA 96

Query: 137 YSGKLVSPKWKNFKGLKLQWRDKIRLNNAIWRAWYMQYLEKRKNPVCHFVTPLDGSVDVD 196
           YSGKLVSPKWKNFKGLKL  RDKIRLNNAIWRAWY+QY+++RK+PVC FVTPL G  + D
Sbjct: 97  YSGKLVSPKWKNFKGLKLLCRDKIRLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGP-EAD 155

Query: 197 EHRRPEAITTEGKYWKSRIEIVIREYHKWRTYFKKRLQQ-HKDEDLSSLVQDDDML---- 251
            HR+PEA+  EG YWK RIE+V+REYHKWR Y+KKRL++  +++DL +  Q +       
Sbjct: 156 AHRKPEAVVLEGNYWKRRIEVVMREYHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPE 215

Query: 252 YWHKHGDGWKTPVPM---EEDP----LLDTDMLMSEFSDTLFSTLSSHQPVAWPNPREIA 304
            W K       PV +   EE+P    LLD +  +S+ SDTLF T++   P     P E A
Sbjct: 216 QWCKQLFSSVVPVLLGDPEEEPGGRQLLDLNCFLSDISDTLF-TMTQSGPSPLQLPPEDA 274

Query: 305 HLGNADMIQPGLIPLQPNLD-FMDTFEPFQDLFSSSRSIFGSMLPASASAPVPDPNNPPA 363
           ++GNADMIQP L PLQP+LD FMD      D F++SR       P  ++ P P P+  P 
Sbjct: 275 YVGNADMIQPDLTPLQPSLDDFMD----ISDFFTNSRL---PQPPMPSNFPEP-PSFSPV 326

Query: 364 QESILPTTAL-PTVSLPDSLIAPPTAPSLAHMD-------EQGC----EHTSRTEDPFIQ 411
            +S+  +  L P V        PP + ++ H+           C    + ++     F+ 
Sbjct: 327 VDSLFSSGTLGPEV--------PPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLL 378

Query: 412 PTDFGPSEPPLSVPQPFL---PVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTF 468
           P D  P  PP  VP P L   P   +P L P P PP      P + PP   L     P F
Sbjct: 379 PEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPP-----FPPMAPPTALLQEE--PLF 431

Query: 469 HQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPV 528
                F  V  AP V    A A      P T  S           P+P+  P  + L P+
Sbjct: 432 SPRFPFPTVPPAPGVSPLPAPAAF----PPTPQSV----------PSPAPTPFPIELLPL 477

Query: 529 T-RPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAAFSGQPQAV 587
               P     F  P+      G+P         P P P         +APA  S  P   
Sbjct: 478 GYSEPAFGPCFSMPR------GKP---------PAPSPRGQKASPPTLAPATAS--PPTT 520

Query: 588 IMTSGPLKREGMLASTVSQS-NVVIAPAAIARAPG-----VPEFHSSILVTDLGHGTSSP 641
             ++ P   + + A+   Q+    +  + + R+PG     VPEF  + L          P
Sbjct: 521 AGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRP 580

Query: 642 PAPVSRLFPSTAQ-DPLGKGEQVPLHGGSPQVTVTGPSRDCPNSGQASPCASEQSP--SP 698
           P   + L PS     P  +    P   GS +  ++G     P  G  S   S   P  S 
Sbjct: 581 PPGPATLAPSRPLLVPKAERLSPPAPSGSER-RLSGDLSSMPGPGTLSVRVSPPQPILSR 639

Query: 699 QSPQNNCSGKSDPKNVAALKNRQMKHISAEQKRRFNIKMCFDMLNSLISNNSKL----TS 754
             P +N             KNR++ HISAEQKRRFNIK+ FD L+ L+S  S       S
Sbjct: 640 GRPDSN-------------KNRRITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKVS 686

Query: 755 HAITLQKTVEYITKLQQERGQMQEEARRLREEIEELNATIISCQQLLPATGVPVTRRQFD 814
            A TLQKT EYI  LQQER  +QEEA++LR+EIEELNA I  CQQ LPATGVP+T ++FD
Sbjct: 687 KATTLQKTAEYILMLQQERAGLQEEAQQLRDEIEELNAAINLCQQQLPATGVPITHQRFD 746

Query: 815 HMKDMFDEYVKTRTLQNWKFWIFSIIIKPLFESFKGMVSTSSLEELHRTALSWLDQHCSL 874
            M+DMFD+YV+TRTL NWKFW+FSI+I+PLFESF GMVST+S+  L +T+L+WLDQ+CSL
Sbjct: 747 QMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASVHTLRQTSLAWLDQYCSL 806

Query: 875 PILRPMVLSTLRQLSTSTSILTDPAQLPEQASKAVTR--IGKRL 916
           P LRP VL++LRQL TSTSILTDP ++PEQA++AVT   +GK L
Sbjct: 807 PALRPTVLNSLRQLGTSTSILTDPGRIPEQATRAVTEGTLGKPL 850


>gi|14602433 Williams Beuren syndrome chromosome region 14 isoform
           alpha [Homo sapiens]
          Length = 852

 Score =  549 bits (1415), Expect = e-156
 Identities = 384/944 (40%), Positives = 503/944 (53%), Gaps = 146/944 (15%)

Query: 17  GRQVLLKPQVSEDDDDSDTDEPSPPPASGAATPARAHASAAPPPPRAGPGREEPPRRQQI 76
           G QV       + D D+D+++PS   ++G                           R Q+
Sbjct: 11  GLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLL------------------------RSQV 46

Query: 77  IHSGHFMVSSPHREHPPKKGYDFDTVNKQTCQTYSFGKTSSCHLSIDASLTKLFECMTLA 136
           IHSGHFMVSSPH +  P++            Q  S G +     SID +LT+LFEC++LA
Sbjct: 47  IHSGHFMVSSPHSDSLPRR----------RDQEGSVGPSDFGPRSIDPTLTRLFECLSLA 96

Query: 137 YSGKLVSPKWKNFKGLKLQWRDKIRLNNAIWRAWYMQYLEKRKNPVCHFVTPLDGSVDVD 196
           YSGKLVSPKWKNFKGLKL  RDKIRLNNAIWRAWY+QY+++RK+PVC FVTPL G  + D
Sbjct: 97  YSGKLVSPKWKNFKGLKLLCRDKIRLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGP-EAD 155

Query: 197 EHRRPEAITTEGKYWKSRIEIVIREYHKWRTYFKKRLQQ-HKDEDLSSLVQDDDML---- 251
            HR+PEA+  EG YWK RIE+V+REYHKWR Y+KKRL++  +++DL +  Q +       
Sbjct: 156 AHRKPEAVVLEGNYWKRRIEVVMREYHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPE 215

Query: 252 YWHKHGDGWKTPVPM---EEDP----LLDTDMLMSEFSDTLFSTLSSHQPVAWPNPREIA 304
            W K       PV +   EE+P    LLD +  +S+ SDTLF T++   P     P E A
Sbjct: 216 QWCKQLFSSVVPVLLGDPEEEPGGRQLLDLNCFLSDISDTLF-TMTQSGPSPLQLPPEDA 274

Query: 305 HLGNADMIQPGLIPLQPNLD-FMDTFEPFQDLFSSSRSIFGSMLPASASAPVPDPNNPPA 363
           ++GNADMIQP L PLQP+LD FMD      D F++SR       P  ++ P P P+  P 
Sbjct: 275 YVGNADMIQPDLTPLQPSLDDFMD----ISDFFTNSRL---PQPPMPSNFPEP-PSFSPV 326

Query: 364 QESILPTTAL-PTVSLPDSLIAPPTAPSLAHMD-------EQGC----EHTSRTEDPFIQ 411
            +S+  +  L P V        PP + ++ H+           C    + ++     F+ 
Sbjct: 327 VDSLFSSGTLGPEV--------PPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLL 378

Query: 412 PTDFGPSEPPLSVPQPFL---PVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTF 468
           P D  P  PP  VP P L   P   +P L P P PP      P + PP   L     P F
Sbjct: 379 PEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPP-----FPPMAPPTALLQEE--PLF 431

Query: 469 HQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPV 528
                F  V  AP V    A A      P T  S           P+P+  P  + L P+
Sbjct: 432 SPRFPFPTVPPAPGVSPLPAPAAF----PPTPQSV----------PSPAPTPFPIELLPL 477

Query: 529 T-RPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAAFSGQPQAV 587
               P     F  P+      G+P         P P P         +APA  S  P   
Sbjct: 478 GYSEPAFGPCFSMPR------GKP---------PAPSPRGQKASPPTLAPATAS--PPTT 520

Query: 588 IMTSGPLKREGMLASTVSQS-NVVIAPAAIARAPG-----VPEFHSSILVTDLGHGTSSP 641
             ++ P   + + A+   Q+    +  + + R+PG     VPEF  + L          P
Sbjct: 521 AGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRP 580

Query: 642 PAPVSRLFPSTAQ-DPLGKGEQVPLHGGSPQVTVTGPSRDCPNSGQASPCASEQSP--SP 698
           P   + L PS     P  +    P   GS +  ++G     P  G  S   S   P  S 
Sbjct: 581 PPGPATLAPSRPLLVPKAERLSPPAPSGSER-RLSGDLSSMPGPGTLSVRVSPPQPILSR 639

Query: 699 QSPQNNCSGKSDPKNVAALKNRQMKHISAEQKRRFNIKMCFDMLNSLISNNSKL----TS 754
             P +N +           +NR++ HISAEQKRRFNIK+ FD L+ L+S  S       S
Sbjct: 640 GRPDSNKT-----------ENRRITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKVS 688

Query: 755 HAITLQKTVEYITKLQQERGQMQEEARRLREEIEELNATIISCQQLLPATGVPVTRRQFD 814
            A TLQKT EYI  LQQER  +QEEA++LR+EIEELNA I  CQQ LPATGVP+T ++FD
Sbjct: 689 KATTLQKTAEYILMLQQERAGLQEEAQQLRDEIEELNAAINLCQQQLPATGVPITHQRFD 748

Query: 815 HMKDMFDEYVKTRTLQNWKFWIFSIIIKPLFESFKGMVSTSSLEELHRTALSWLDQHCSL 874
            M+DMFD+YV+TRTL NWKFW+FSI+I+PLFESF GMVST+S+  L +T+L+WLDQ+CSL
Sbjct: 749 QMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASVHTLRQTSLAWLDQYCSL 808

Query: 875 PILRPMVLSTLRQLSTSTSILTDPAQLPEQASKAVTR--IGKRL 916
           P LRP VL++LRQL TSTSILTDP ++PEQA++AVT   +GK L
Sbjct: 809 PALRPTVLNSLRQLGTSTSILTDPGRIPEQATRAVTEGTLGKPL 852


>gi|14602439 Williams Beuren syndrome chromosome region 14 isoform
           delta [Homo sapiens]
          Length = 831

 Score =  525 bits (1352), Expect = e-149
 Identities = 373/940 (39%), Positives = 491/940 (52%), Gaps = 159/940 (16%)

Query: 17  GRQVLLKPQVSEDDDDSDTDEPSPPPASGAATPARAHASAAPPPPRAGPGREEPPRRQQI 76
           G QV       + D D+D+++PS   ++G                           R Q+
Sbjct: 11  GLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLL------------------------RSQV 46

Query: 77  IHSGHFMVSSPHREHPPKKGYDFDTVNKQTCQTYSFGKTSSCHLSIDASLTKLFECMTLA 136
           IHSGHFMVSSPH +  P++            Q  S G +     SID +LT+LFEC++LA
Sbjct: 47  IHSGHFMVSSPHSDSLPRR----------RDQEGSVGPSDFGPRSIDPTLTRLFECLSLA 96

Query: 137 YSGKLVSPKWKNFKGLKLQWRDKIRLNNAIWRAWYMQYLEKRKNPVCHFVTPLDGSVDVD 196
           YSGKLVSPKWKNFKGLKL  RDKIRLNNAIWRAWY+QY+++RK+PVC FVTPL G  + D
Sbjct: 97  YSGKLVSPKWKNFKGLKLLCRDKIRLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGP-EAD 155

Query: 197 EHRRPEAITTEGKYWKSRIEIVIREYHKWRTYFKKRLQQ-HKDEDLSSLVQDDDML---- 251
            HR+PEA+  EG YWK RIE+V+REYHKWR Y+KKRL++  +++DL +  Q +       
Sbjct: 156 AHRKPEAVVLEGNYWKRRIEVVMREYHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPE 215

Query: 252 YWHKHGDGWKTPVPM---EEDP----LLDTDMLMSEFSDTLFSTLSSHQPVAWPNPREIA 304
            W K       PV +   EE+P    LLD +  +S+ SDTLF T++   P     P E A
Sbjct: 216 QWCKQLFSSVVPVLLGDPEEEPGGRQLLDLNCFLSDISDTLF-TMTQSGPSPLQLPPEDA 274

Query: 305 HLGNADMIQPGLIPLQPNLD-FMDTFEPFQDLFSSSRSIFGSMLPASASAPVPDPNNPPA 363
           ++GNADMIQP L PLQP+LD FMD      D F++SR       P  ++ P P P+  P 
Sbjct: 275 YVGNADMIQPDLTPLQPSLDDFMD----ISDFFTNSRL---PQPPMPSNFPEP-PSFSPV 326

Query: 364 QESILPTTAL-PTVSLPDSLIAPPTAPSLAHMD-------EQGC----EHTSRTEDPFIQ 411
            +S+  +  L P V        PP + ++ H+           C    + ++     F+ 
Sbjct: 327 VDSLFSSGTLGPEV--------PPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLL 378

Query: 412 PTDFGPSEPPLSVPQPFL---PVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTF 468
           P D  P  PP  VP P L   P   +P L P P PP      P + PP   L     P F
Sbjct: 379 PEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPP-----FPPMAPPTALLQEE--PLF 431

Query: 469 HQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPV 528
                F  V  AP V    A A      P T  S           P+P+  P  + L P+
Sbjct: 432 SPRFPFPTVPPAPGVSPLPAPAAF----PPTPQSV----------PSPAPTPFPIELLPL 477

Query: 529 T-RPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAAFSGQPQAV 587
               P     F  P+      G+P         P P P         +APA  S  P   
Sbjct: 478 GYSEPAFGPCFSMPR------GKP---------PAPSPRGQKASPPTLAPATAS--PPTT 520

Query: 588 IMTSGPLKREGMLASTVSQS-NVVIAPAAIARAPG-----VPEFHSSILVTDLGHGTSSP 641
             ++ P   + + A+   Q+    +  + + R+PG     VPEF  + L          P
Sbjct: 521 AGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRP 580

Query: 642 PAPVSRLFPSTAQ-DPLGKGEQVPLHGGSPQVTVTGPSRDCPNSGQASPCASEQSP--SP 698
           P   + L PS     P  +    P   GS +  ++G     P  G  S   S   P  S 
Sbjct: 581 PPGPATLAPSRPLLVPKAERLSPPAPSGSER-RLSGDLSSMPGPGTLSVRVSPPQPILSR 639

Query: 699 QSPQNNCSGKSDPKNVAALKNRQMKHISAEQKRRFNIKMCFDMLNSLISNNSKLTSHAIT 758
             P +N             KNR++ HISAEQKRRFNIK+ FD L+ L+S  S   S    
Sbjct: 640 GRPDSN-------------KNRRITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPS---- 682

Query: 759 LQKTVEYITKLQQERGQMQEEARRLREEIEELNATIISCQQLLPATGVPVTRRQFDHMKD 818
                       +ER  +QEEA++LR+EIEELNA I  CQQ LPATGVP+T ++FD M+D
Sbjct: 683 -----------LKERAGLQEEAQQLRDEIEELNAAINLCQQQLPATGVPITHQRFDQMRD 731

Query: 819 MFDEYVKTRTLQNWKFWIFSIIIKPLFESFKGMVSTSSLEELHRTALSWLDQHCSLPILR 878
           MFD+YV+TRTL NWKFW+FSI+I+PLFESF GMVST+S+  L +T+L+WLDQ+CSLP LR
Sbjct: 732 MFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASVHTLRQTSLAWLDQYCSLPALR 791

Query: 879 PMVLSTLRQLSTSTSILTDPAQLPEQASKAVTR--IGKRL 916
           P VL++LRQL TSTSILTDP ++PEQA++AVT   +GK L
Sbjct: 792 PTVLNSLRQLGTSTSILTDPGRIPEQATRAVTEGTLGKPL 831


>gi|14602435 Williams Beuren syndrome chromosome region 14 isoform
           beta [Homo sapiens]
          Length = 833

 Score =  523 bits (1348), Expect = e-148
 Identities = 372/940 (39%), Positives = 492/940 (52%), Gaps = 157/940 (16%)

Query: 17  GRQVLLKPQVSEDDDDSDTDEPSPPPASGAATPARAHASAAPPPPRAGPGREEPPRRQQI 76
           G QV       + D D+D+++PS   ++G                           R Q+
Sbjct: 11  GLQVPRVAPSPDSDSDTDSEDPSLRRSAGGLL------------------------RSQV 46

Query: 77  IHSGHFMVSSPHREHPPKKGYDFDTVNKQTCQTYSFGKTSSCHLSIDASLTKLFECMTLA 136
           IHSGHFMVSSPH +  P++            Q  S G +     SID +LT+LFEC++LA
Sbjct: 47  IHSGHFMVSSPHSDSLPRR----------RDQEGSVGPSDFGPRSIDPTLTRLFECLSLA 96

Query: 137 YSGKLVSPKWKNFKGLKLQWRDKIRLNNAIWRAWYMQYLEKRKNPVCHFVTPLDGSVDVD 196
           YSGKLVSPKWKNFKGLKL  RDKIRLNNAIWRAWY+QY+++RK+PVC FVTPL G  + D
Sbjct: 97  YSGKLVSPKWKNFKGLKLLCRDKIRLNNAIWRAWYIQYVKRRKSPVCGFVTPLQGP-EAD 155

Query: 197 EHRRPEAITTEGKYWKSRIEIVIREYHKWRTYFKKRLQQ-HKDEDLSSLVQDDDML---- 251
            HR+PEA+  EG YWK RIE+V+REYHKWR Y+KKRL++  +++DL +  Q +       
Sbjct: 156 AHRKPEAVVLEGNYWKRRIEVVMREYHKWRIYYKKRLRKPSREDDLLAPKQAEGRWPPPE 215

Query: 252 YWHKHGDGWKTPVPM---EEDP----LLDTDMLMSEFSDTLFSTLSSHQPVAWPNPREIA 304
            W K       PV +   EE+P    LLD +  +S+ SDTLF T++   P     P E A
Sbjct: 216 QWCKQLFSSVVPVLLGDPEEEPGGRQLLDLNCFLSDISDTLF-TMTQSGPSPLQLPPEDA 274

Query: 305 HLGNADMIQPGLIPLQPNLD-FMDTFEPFQDLFSSSRSIFGSMLPASASAPVPDPNNPPA 363
           ++GNADMIQP L PLQP+LD FMD      D F++SR       P  ++ P P P+  P 
Sbjct: 275 YVGNADMIQPDLTPLQPSLDDFMD----ISDFFTNSRL---PQPPMPSNFPEP-PSFSPV 326

Query: 364 QESILPTTAL-PTVSLPDSLIAPPTAPSLAHMD-------EQGC----EHTSRTEDPFIQ 411
            +S+  +  L P V        PP + ++ H+           C    + ++     F+ 
Sbjct: 327 VDSLFSSGTLGPEV--------PPASSAMTHLSGHSRLQARNSCPGPLDSSAFLSSDFLL 378

Query: 412 PTDFGPSEPPLSVPQPFL---PVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTF 468
           P D  P  PP  VP P L   P   +P L P P PP      P + PP   L     P F
Sbjct: 379 PEDPKPRLPPPPVPPPLLHYPPPAKVPGLEPCPPPP-----FPPMAPPTALLQEE--PLF 431

Query: 469 HQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPV 528
                F  V  AP V    A A      P T  S           P+P+  P  + L P+
Sbjct: 432 SPRFPFPTVPPAPGVSPLPAPAAF----PPTPQSV----------PSPAPTPFPIELLPL 477

Query: 529 T-RPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAAFSGQPQAV 587
               P     F  P+      G+P         P P P         +APA  S  P   
Sbjct: 478 GYSEPAFGPCFSMPR------GKP---------PAPSPRGQKASPPTLAPATAS--PPTT 520

Query: 588 IMTSGPLKREGMLASTVSQS-NVVIAPAAIARAPG-----VPEFHSSILVTDLGHGTSSP 641
             ++ P   + + A+   Q+    +  + + R+PG     VPEF  + L          P
Sbjct: 521 AGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGSPQETVPEFPCTFLPPTPAPTPPRP 580

Query: 642 PAPVSRLFPSTAQ-DPLGKGEQVPLHGGSPQVTVTGPSRDCPNSGQASPCASEQSP--SP 698
           P   + L PS     P  +    P   GS +  ++G     P  G  S   S   P  S 
Sbjct: 581 PPGPATLAPSRPLLVPKAERLSPPAPSGSER-RLSGDLSSMPGPGTLSVRVSPPQPILSR 639

Query: 699 QSPQNNCSGKSDPKNVAALKNRQMKHISAEQKRRFNIKMCFDMLNSLISNNSKLTSHAIT 758
             P +N +           +NR++ HISAEQKRRFNIK+ FD L+ L+S  S   S    
Sbjct: 640 GRPDSNKT-----------ENRRITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPS---- 684

Query: 759 LQKTVEYITKLQQERGQMQEEARRLREEIEELNATIISCQQLLPATGVPVTRRQFDHMKD 818
                       +ER  +QEEA++LR+EIEELNA I  CQQ LPATGVP+T ++FD M+D
Sbjct: 685 -----------LKERAGLQEEAQQLRDEIEELNAAINLCQQQLPATGVPITHQRFDQMRD 733

Query: 819 MFDEYVKTRTLQNWKFWIFSIIIKPLFESFKGMVSTSSLEELHRTALSWLDQHCSLPILR 878
           MFD+YV+TRTL NWKFW+FSI+I+PLFESF GMVST+S+  L +T+L+WLDQ+CSLP LR
Sbjct: 734 MFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASVHTLRQTSLAWLDQYCSLPALR 793

Query: 879 PMVLSTLRQLSTSTSILTDPAQLPEQASKAVTR--IGKRL 916
           P VL++LRQL TSTSILTDP ++PEQA++AVT   +GK L
Sbjct: 794 PTVLNSLRQLGTSTSILTDPGRIPEQATRAVTEGTLGKPL 833


>gi|38201614 transcription factor-like protein 4 isoform alpha [Homo
           sapiens]
          Length = 214

 Score = 86.7 bits (213), Expect = 9e-17
 Identities = 55/177 (31%), Positives = 90/177 (50%), Gaps = 21/177 (11%)

Query: 720 RQMKHISAEQKRRFNIKMCFDMLNSLI--------SNNSKLTSHAITLQKTVEYITKLQQ 771
           R+  H  AEQKRR  IK  +D L +++        S  S+  S AI LQKT++YI  L +
Sbjct: 46  RRRAHTQAEQKRRDAIKRGYDDLQTIVPTCQQQDFSIGSQKLSKAIVLQKTIDYIQFLHK 105

Query: 772 ERGQMQEEARRLREEIEELNATIISCQQLLPATGVPVTRRQFDHMKDMFDEYVKTRTLQN 831
           E+ + +EE   LR+++  L    ++ +Q++ A           H  +  +   + +    
Sbjct: 106 EKKKQEEEVSTLRKDVTALKIMKVNYEQIVKA-----------HQDNPHEG--EDQVSDQ 152

Query: 832 WKFWIFSIIIKPLFESFKGMVSTSSLEELHRTALSWLDQHCSLPILRPMVLSTLRQL 888
            KF +F  I+  LF+SF   +S +S +EL     SW+++HC    LR +V+  L QL
Sbjct: 153 VKFNVFQGIMDSLFQSFNASISVASFQELSACVFSWIEEHCKPQTLREIVIGVLHQL 209


>gi|38201612 transcription factor-like protein 4 isoform beta [Homo
           sapiens]
          Length = 244

 Score = 86.7 bits (213), Expect = 9e-17
 Identities = 55/177 (31%), Positives = 90/177 (50%), Gaps = 21/177 (11%)

Query: 720 RQMKHISAEQKRRFNIKMCFDMLNSLI--------SNNSKLTSHAITLQKTVEYITKLQQ 771
           R+  H  AEQKRR  IK  +D L +++        S  S+  S AI LQKT++YI  L +
Sbjct: 76  RRRAHTQAEQKRRDAIKRGYDDLQTIVPTCQQQDFSIGSQKLSKAIVLQKTIDYIQFLHK 135

Query: 772 ERGQMQEEARRLREEIEELNATIISCQQLLPATGVPVTRRQFDHMKDMFDEYVKTRTLQN 831
           E+ + +EE   LR+++  L    ++ +Q++ A           H  +  +   + +    
Sbjct: 136 EKKKQEEEVSTLRKDVTALKIMKVNYEQIVKA-----------HQDNPHEG--EDQVSDQ 182

Query: 832 WKFWIFSIIIKPLFESFKGMVSTSSLEELHRTALSWLDQHCSLPILRPMVLSTLRQL 888
            KF +F  I+  LF+SF   +S +S +EL     SW+++HC    LR +V+  L QL
Sbjct: 183 VKFNVFQGIMDSLFQSFNASISVASFQELSACVFSWIEEHCKPQTLREIVIGVLHQL 239


>gi|24586667 transcription factor-like protein 4 isoform gamma [Homo
           sapiens]
          Length = 298

 Score = 86.7 bits (213), Expect = 9e-17
 Identities = 55/177 (31%), Positives = 90/177 (50%), Gaps = 21/177 (11%)

Query: 720 RQMKHISAEQKRRFNIKMCFDMLNSLI--------SNNSKLTSHAITLQKTVEYITKLQQ 771
           R+  H  AEQKRR  IK  +D L +++        S  S+  S AI LQKT++YI  L +
Sbjct: 130 RRRAHTQAEQKRRDAIKRGYDDLQTIVPTCQQQDFSIGSQKLSKAIVLQKTIDYIQFLHK 189

Query: 772 ERGQMQEEARRLREEIEELNATIISCQQLLPATGVPVTRRQFDHMKDMFDEYVKTRTLQN 831
           E+ + +EE   LR+++  L    ++ +Q++ A           H  +  +   + +    
Sbjct: 190 EKKKQEEEVSTLRKDVTALKIMKVNYEQIVKA-----------HQDNPHEG--EDQVSDQ 236

Query: 832 WKFWIFSIIIKPLFESFKGMVSTSSLEELHRTALSWLDQHCSLPILRPMVLSTLRQL 888
            KF +F  I+  LF+SF   +S +S +EL     SW+++HC    LR +V+  L QL
Sbjct: 237 VKFNVFQGIMDSLFQSFNASISVASFQELSACVFSWIEEHCKPQTLREIVIGVLHQL 293


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 103/411 (25%), Positives = 137/411 (33%), Gaps = 56/411 (13%)

Query: 332  FQDLFSSSRSIFGSMLPASASAPVPDPNNPPAQESI-LPTTALPT---VSLP-----DSL 382
            FQ    S  +      P+   AP P    P + + + LP    PT   V+LP      + 
Sbjct: 843  FQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPAT 902

Query: 383  IAPPTAPSLAHMDEQGCEHTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPA 442
             AP  AP+L+ M     +    T  P   P     S  P   P P       P   P+  
Sbjct: 903  PAPKQAPALS-MTSSSPKKARATPAPKGIPA----SPSPKGAPTPPAATPPSPKGGPATP 957

Query: 443  PPPISPVLPLVPPPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFS 502
             P  +P  P   PP+    P  P     P   A    +P     T S       PA T  
Sbjct: 958  SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP 1017

Query: 503  QSQGLVITTHHPAPSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPK 562
              +G       PA +  P G +  P   PP P+ +   P    L  G P  P   +P+PK
Sbjct: 1018 SPKG------SPAATPFPKGASTPPAATPPSPKGS---PAATPLPKGAPTTPAATLPSPK 1068

Query: 563  PEPVSLVLKNARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIARAP-- 620
              P +  LK A   PAA    P+      GP        +T S     + PAA   +P  
Sbjct: 1069 GGPATPSLKGAPTPPAATPPSPK-----GGP--------ATPSPKGAPMPPAATPPSPKG 1115

Query: 621  --------GVPEFHSSILVTDLGHGTSSPPAPVSRLFPSTAQDPLGKGEQVPLHGGSPQV 672
                    G P   ++   +  G   + PP        +T   P G     P  G     
Sbjct: 1116 GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1175

Query: 673  TVTGPSRDCPNSGQASP-------CASEQSPSPQSPQNNCSGKSDPKNVAA 716
              T PS   P  G A+P         +   PSP+      S K  P   AA
Sbjct: 1176 AATPPS---PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1223



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 100/403 (24%), Positives = 133/403 (33%), Gaps = 61/403 (15%)

Query: 348  PASASAPV----PDPNNPPAQESI---LPTTALPTVSLPD------SLIAPPTAPSLAHM 394
            P  AS P     P P   PA   +    PTT   T+  P       SL   PT P+    
Sbjct: 1029 PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPP 1088

Query: 395  DEQGCEHTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSP-------SPAPPPIS 447
              +G   T   +   + P    PS        P     T P  +P       +  PP  +
Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGA 1148

Query: 448  PVLPLVPPPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGL 507
            P  P   PP+       PP    P   A    +P     T S       PA T    +G 
Sbjct: 1149 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1208

Query: 508  VITTHHPAPSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVS 567
            + T   P+P  AP     +P   PP P+     P P     G P  P    P+PK  P +
Sbjct: 1209 LAT---PSPKGAP----TTPAATPPSPKGGLATPSP----KGAPTTPAATPPSPKGGPAT 1257

Query: 568  LVLKNARIAPAA-------------FSGQPQAVIMTSGPLKREGMLASTV--SQSNVVIA 612
               K A   PAA               G P   ++T  P  + G   S    + +     
Sbjct: 1258 PPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP-PSPKGGPATSPPKGAPTPPAAT 1316

Query: 613  PAAIARAPGVPEFHSS----ILVTDLGHGTSSPPA--PVSRLFPSTAQDPLG--KGEQVP 664
            P +   +PG P    +     +      GT + PA  P S+  P+T     G       P
Sbjct: 1317 PPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATP 1376

Query: 665  LHGGSPQVTVTGPSR----DCPNSGQASPCASEQSP--SPQSP 701
             H G P +T   P R      P     SP     SP  +P +P
Sbjct: 1377 SHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATP 1419



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 95/428 (22%), Positives = 136/428 (31%), Gaps = 70/428 (16%)

Query: 344  GSMLPASASAPVPDPNNPPAQESIL--------PTTALPTVSLPDSLIAPP------TAP 389
            G   P+   AP      PP+ +  L        PTT   T   P   +A P      T P
Sbjct: 1185 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1244

Query: 390  SLAHMDEQGCEHTSRTEDPFIQPTDFGPS-------EPPLSVPQPFLPVFTMPLLSPSPA 442
            +      +G   T   +     P    PS        P    P P +     P   P+ +
Sbjct: 1245 AATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATS 1304

Query: 443  PPPISPVLPLVPPPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFS 502
            PP  +P  P   PP+   +P  PP    P   A    +P       + T +     TT S
Sbjct: 1305 PPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPS 1364

Query: 503  QSQGLVITTHHPAPSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPK 562
              +G       P P AA       P   PP P+     P P     G P  P  I  +PK
Sbjct: 1365 SKEG-------PTPPAATPSHKGGPAMTPPSPKRGPAIPSP----KGDPTSPAVIPLSPK 1413

Query: 563  PEPVSLVLKNARIAPAAFSGQPQAVIMTSGPLKREGMLA------STVSQSNVVIAPAAI 616
              P + V +     P+     P AV   S  LK+    +      +T S       PA  
Sbjct: 1414 KAPATPVTREGAATPSKGDLTPPAVTPVS--LKKAPATSAPKGGPATPSSKGDPTLPAVT 1471

Query: 617  ARAPGVPEFHSSILVTDLGHGTSSPPAPVSR---------------LFPSTAQDPLGK-- 659
              +P  P     +  +       + PAP+                   PS+ +DP+    
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTA 1531

Query: 660  ---GEQVPLHGG------SPQVTVTGPSR----DCPNSGQASPCASEQSPSPQSPQNNCS 706
                ++ P           P +TV  P +      P    A+P + E S  P    +   
Sbjct: 1532 TLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYK 1591

Query: 707  GKSDPKNV 714
            G   PK +
Sbjct: 1592 GAPSPKEL 1599



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 95/424 (22%), Positives = 156/424 (36%), Gaps = 83/424 (19%)

Query: 356  PDPNNPPAQESILPTT--ALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQPT 413
            PD   P  + S++  T  A P  S   + +AP TA        +G    + T  PF++ T
Sbjct: 629  PDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTA--------KGTSTYTTTASPFLEGT 680

Query: 414  DFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISP----------VLPLVPP-PATALNP 462
                S  P + P     + T+PL+  +    P++P           L L P  P +  +P
Sbjct: 681  ---VSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSP 737

Query: 463  PAPPTFHQP--QKFAGVNKAPSV--ITHTASATLTHDAPATTFSQSQGLVITTHHPAPSA 518
              PP    P  +K  G++   ++  +  +     T D+ A+  + S+G   T  + A S 
Sbjct: 738  SLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKG---TLTYLADSP 794

Query: 519  APCGLALSPVT-RPPQPR--------------------LTFVHPKPVSLTGGR--PKQPH 555
            +P G+++SP T RPP  +                     +F+    +S  G +  P   H
Sbjct: 795  SPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTH 854

Query: 556  KIVP-----APKPEPVSLVLKNARIAPAAFSGQPQAVIMTSGPLKREG------------ 598
               P     AP P  V+ +       P   +  P  V +   P  +EG            
Sbjct: 855  SPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNL---PFPKEGPATPAPKQAPAL 911

Query: 599  -MLASTVSQSNVVIAPAAIARAPGVPEFHSSILVTDLG-HGTSSPPAPVSRLFPSTAQDP 656
             M +S+  ++    AP  I  +P      +    T     G  + P+P     P  A  P
Sbjct: 912  SMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPP 971

Query: 657  LGK-GEQVPLHGGSPQVTVTGPSRDCPNSGQASP----CASEQSPSPQSPQNNCSGKSDP 711
              K G   P   G+P      P    P  G A+P      +  + +P SP+ + +    P
Sbjct: 972  SPKGGPATPSPKGAPTPPAATP--PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFP 1029

Query: 712  KNVA 715
            K  +
Sbjct: 1030 KGAS 1033



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 93/397 (23%), Positives = 146/397 (36%), Gaps = 72/397 (18%)

Query: 347 LPASASAPVPDPNN----PPAQESILPTTALPTVSL----PDSLIAPPTAPSLAHMDEQG 398
           +P  A+  VP        P A+ ++LP ++  +V+     P   + PP +P+      Q 
Sbjct: 1   MPGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPA-----PQQ 55

Query: 399 CEHTSRTE-DPFIQPTDFGPSEPPLSVPQP------FLPVFT---MPLLSPSPAPPPISP 448
           C  ++  +  PF  P+    +  PL VP P       LP+ T    P   P+   PPISP
Sbjct: 56  CPLSAANQASPFPSPSTI--ASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISP 113

Query: 449 VLPLVPPPATALNPPAPPTFHQPQKFAGVNKAPSVITHTAS--ATLTHDAPATTFSQSQG 506
               +  P  A      P+   P   A V  AP  +  +++    L    P+   ++S G
Sbjct: 114 AALALASPMIAPTLKGTPSSSAP--LALVALAPHSVQKSSAFPPNLLTSPPSVAVAES-G 170

Query: 507 LVITTHHP-APSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVP------ 559
            VIT   P APS     L   P    P P+ T   P P  +    P   H + P      
Sbjct: 171 SVITLSAPIAPSEPKTNLNKVPSEVVPNPKGT---PSPPCIVSTVPY--HCVTPMASIQS 225

Query: 560 ----APKPEPVSLV------LKNARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNV 609
                P+  P + +      +K+  I+    S Q    +   GP+     L+ +     V
Sbjct: 226 GVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPV 285

Query: 610 VIAPAAIARAPGVPEFHSSI--LVTDLGHGTSSPPAPVSRLFPSTAQDPLGKGEQVPLHG 667
           V +    A     P+F  S+   +  L   +      + +  PS   DP           
Sbjct: 286 VTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDP----------- 334

Query: 668 GSPQVTVTGPSRDCPNSGQASPCASEQSPSPQSPQNN 704
                TV   S D  ++G + P  S++S  P  P  N
Sbjct: 335 -----TVKTISVDHSSTGASYP--SQRSVIPPLPSRN 364



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 97/406 (23%), Positives = 140/406 (34%), Gaps = 48/406 (11%)

Query: 330 EPFQDLFSSSRSIFGSMLPASASA--PVPDPNNP-PAQESILPTTALPTVSLPDSLIAPP 386
           +P     S   S  G+  P+  S   P+P  N   PA  +  P  A P+V    S I+  
Sbjct: 333 DPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVA-PSVDKGPSTISSI 391

Query: 387 TAPSLAHMDEQGCEHTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPI 446
           T      ++       S T    ++ +       PL    P   V T PL+  +P     
Sbjct: 392 TCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAA 451

Query: 447 SPVLPLVPPPATALNPP---APPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQ 503
           +P        AT ++PP    P +  +P   A +  AP          +    P+T  + 
Sbjct: 452 APTTTF--EVATCVSPPMSSGPISNIEPTSPAALVMAP----------VAPKEPSTQVAT 499

Query: 504 SQGLVITTHHPAPSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKP 563
           +  + ++   P P       +   V  P Q  L  V   P SL G  P  P +     K 
Sbjct: 500 TLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTV---PASLEGA-PFSPAQAGLTTKK 555

Query: 564 EPVSLVLKNARIAPAAFSGQPQAVIMTSGPLKREGMLAS-TVSQSNVVIAPAAIARAPGV 622
           +P  L L  A  AP               PL  E  LA  ++ +   +  PA+   +P  
Sbjct: 556 DPTVLPLVQA--APKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLG 613

Query: 623 PEFHSSILVTDLGHGT--------SSPPAPVSRLFPSTAQDPLG------KGEQVPLHGG 668
               +S++ TD   G         SS   P    FP  + DP G      KG        
Sbjct: 614 VNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTA 673

Query: 669 SPQVTVT---GPSRDCPNSGQAS-----PCASEQSPSPQSPQNNCS 706
           SP +  T    P       G  +     P ASE  P   SPQN C+
Sbjct: 674 SPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCA 719



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 91/455 (20%), Positives = 153/455 (33%), Gaps = 79/455 (17%)

Query: 348  PASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHT-SRTE 406
            P   +   P P  PPA + +  +++        + +  PT P++     +    T S   
Sbjct: 1465 PTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRR 1524

Query: 407  DPFIQ---------PTDFGPSE----PPLSVPQPF-LPVFTMPLLSPSP-------APPP 445
            DP            P    P E    P ++VP P   P    P  +P+        +PP 
Sbjct: 1525 DPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPA 1584

Query: 446  I---------SPVLPLVPPPATALNP---PAPPTFHQPQKFAG--------------VNK 479
            +         SP   L+PP  T+ +P   P PP    P    G              V  
Sbjct: 1585 VTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTP 1644

Query: 480  APSVITHTASATLTHDAPATTFSQSQGLVI---------TTHHPAPSAAPCGLALSPVTR 530
            +    + T+ A++T    AT    S+GL               PAP + P  +  +P  +
Sbjct: 1645 SSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTP--IITAPTRK 1702

Query: 531  PPQPRLTFVHPKPV----SLTGGRPKQPHKIVPAP------------KPEPVSLVLKNAR 574
             PQ + +     P+    S   G       + PAP            K +  S   K   
Sbjct: 1703 GPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPL 1762

Query: 575  IAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSILVTDL 634
              P + +  P         L +    + + + S  V  P A +  P +P      L +  
Sbjct: 1763 APPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPP-KQQFLPSSP 1821

Query: 635  GHGTSSPPAPVSRLFPSTAQDPLGKGEQVPLHGGSPQVTVTGPSRDCPNSGQASPCASEQ 694
            G    SP  P   L P+   + L      P+ GG P  +V        ++G   P  S +
Sbjct: 1822 GLVLESPSKP---LAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAK 1878

Query: 695  SPSPQSPQNNCSGKSDPKNVAALKNRQMKHISAEQ 729
             P  ++ + + +     ++V  L+ +     + +Q
Sbjct: 1879 QPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQ 1913



 Score = 38.5 bits (88), Expect = 0.029
 Identities = 68/326 (20%), Positives = 109/326 (33%), Gaps = 69/326 (21%)

Query: 424 VPQPFLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTFHQPQKFAGVNKAPSV 483
           +PQP      +P+ S       +    P +PPP +    PAP    Q    +  N+A   
Sbjct: 16  LPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCS----PAP----QQCPLSAANQASPF 67

Query: 484 ITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAP--CGLALSPVTRPPQPRLTFVHP 541
            + +  A+   + P    S    L + T   AP+  P   G  +SP        L    P
Sbjct: 68  PSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAA------LALASP 121

Query: 542 KPVSLTGGRPKQPHKI-VPAPKPEPVSLVLKNARIAPAAFSGQPQAVIMTSGP-LKREGM 599
                  G P     + + A  P  V    K++   P   +  P   +  SG  +     
Sbjct: 122 MIAPTLKGTPSSSAPLALVALAPHSVQ---KSSAFPPNLLTSPPSVAVAESGSVITLSAP 178

Query: 600 LASTVSQSNVVIAPAAIARAPGVPEFHSSILVTDLGHGTSSPPAPVSRLFPSTAQDPLGK 659
           +A +  ++N+   P+ +   P                GT SPP  VS             
Sbjct: 179 IAPSEPKTNLNKVPSEVVPNP---------------KGTPSPPCIVS------------- 210

Query: 660 GEQVPLHGGSPQVTVTGPSRDCPNSGQASPCASEQSPSPQ-----------SPQN----N 704
              VP H  +P  ++       P   Q +P  +    SPQ           SPQN    +
Sbjct: 211 --TVPYHCVTPMASIQSGVASLP---QTTPTTTLAIASPQVKDTTISSVLISPQNPGSLS 265

Query: 705 CSGKSDPKNVAALKNRQMKHISAEQK 730
             G   P    +L  + +  +++ QK
Sbjct: 266 LKGPVSPPAALSLSTQSLPVVTSSQK 291


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 80/355 (22%), Positives = 111/355 (31%), Gaps = 47/355 (13%)

Query: 352  SAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQ 411
            S P   P+ PP   + LP T  P+     +   PPT                 T  P I 
Sbjct: 1400 SPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTT----------------TPSPPIT 1443

Query: 412  PTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLV--PPPATALNPPAPPTFH 469
             T    + PP + P P +   T P  + +P+PP  +P  P     PP T    P P T  
Sbjct: 1444 TTT---TPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTP 1500

Query: 470  QPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPVT 529
             P     +   P   T T   T T   P T          TT  P P+  P     +P+T
Sbjct: 1501 SPPTTTPI--TPPASTTTLPPTTTPSPPTT----------TTTTPPPTTTPSPPTTTPIT 1548

Query: 530  RPPQ----PRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAAFSGQPQ 585
             P      P  T   P P + T   P           P P ++        P      P 
Sbjct: 1549 PPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTP--PPTTTPSPPT 1606

Query: 586  AVIMTSGPLKREGMLAS---TVSQSNVVIAPAAIARAPGVPEFHSSILVTDLGHGTSSPP 642
                T  P        +   T   S   + P      P           T     T++P 
Sbjct: 1607 TTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPS 1666

Query: 643  APVSRLFPSTAQDPLGKGEQVPLHGGSPQVTVTGPSRDCPNSGQASPCASEQSPS 697
             P++    +T          +      P  T+T PS   P +  +SP  +  +PS
Sbjct: 1667 PPITT--TTTPPPTTTPSSPITTTPSPPTTTMTTPS---PTTTPSSPITTTTTPS 1716



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 88/383 (22%), Positives = 122/383 (31%), Gaps = 33/383 (8%)

Query: 348  PASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTED 407
            P + +   P P   P+   I  TT  P  + P   I+  T P             S    
Sbjct: 1424 PPTTTTTTPPPTTTPS-PPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTT 1482

Query: 408  PFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLP----LVPPPATALNPP 463
                PT    + PP + P P       P  S +  PP  +P  P      PPP T  +PP
Sbjct: 1483 TPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPP 1542

Query: 464  -----APPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSA 518
                  PPT             P   T T   T T   P TT      +  TT  P  + 
Sbjct: 1543 TTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTP 1602

Query: 519  APCGLALS---PVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARI 575
            +P     +   P T P  P  T + P P S T      P    P+P P   +        
Sbjct: 1603 SPPTTTTTTPPPTTTPSPPTTTPITP-PTSTT----TLPPTTTPSPPPTTTTTPPPTTTP 1657

Query: 576  APAAFSGQPQAVIMTSGP---LKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSILVT 632
            +P   +     +  T+ P         + +T S     +   +    P  P     I  T
Sbjct: 1658 SPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSP-----ITTT 1712

Query: 633  DLGHGTSSP-PAPVSRLFPSTAQDPLGKGEQV----PLHGGSPQVTVTGPSRDCPNSGQA 687
                 T++P P P +   PS    P      +    P    SP  T   P    P +   
Sbjct: 1713 TTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPT--F 1770

Query: 688  SPCASEQSPSPQSPQNNCSGKSD 710
            SP ++    +P  P  N +G  D
Sbjct: 1771 SPFSTTTPTTPCVPLCNWTGWLD 1793



 Score = 57.0 bits (136), Expect = 8e-08
 Identities = 91/365 (24%), Positives = 116/365 (31%), Gaps = 54/365 (14%)

Query: 354  PVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQP- 412
            P P     P    I  TT +     P     P T P             + T+ P   P 
Sbjct: 3981 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4040

Query: 413  ---TDFGPSEPPLSVPQP-FLPVFTMPLLSPSPAP-----PPISPV-----LPLVPPPAT 458
               T   P+  P     P   P+ T   ++P+P P     P  +P+     +   P P  
Sbjct: 4041 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4100

Query: 459  ALNPPAPP----TFHQPQKFAGVNKAPSVITHTASATLT-HDAPATTFSQSQGLVITTHH 513
               P   P    T   P       + P+    T + T+T    P  T + +   + TT  
Sbjct: 4101 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4160

Query: 514  PAPSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNA 573
              P+  P G      T  P    T V P P   TG +   P     AP  E   L   N 
Sbjct: 4161 VTPTPTPTGTQTPTTT--PITTTTTVTPTPTP-TGTQTGPPTHTSTAPIAE---LTTSN- 4213

Query: 574  RIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSILVTD 633
               P   S  PQ    TS PL     L ST+        P AI      P    +   T 
Sbjct: 4214 ---PPPESSTPQTSRSTSSPLTESTTLLSTL--------PPAIEMTSTAPPSTPTAPTTT 4262

Query: 634  LGHGTSSPPAPVSRLFPSTAQDPLGKGEQVPLHGGSPQVTVTGPSRDCPNSGQASPCASE 693
             G  T SPP       PST   P G     P  G     T TG S     S   +   S 
Sbjct: 4263 SGGHTLSPP-------PSTTTSPPG----TPTRG-----TTTGSSSAPTPSTVQTTTTSA 4306

Query: 694  QSPSP 698
             +P+P
Sbjct: 4307 WTPTP 4311



 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 68/297 (22%), Positives = 92/297 (30%), Gaps = 23/297 (7%)

Query: 420  PPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPP-----APPTFHQPQKF 474
            PP + P P  P  +   L P+  P P        PPP T  +PP      PP    P   
Sbjct: 1401 PPTTTPSP--PPTSTTTLPPTTTPSP-PTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPP 1457

Query: 475  AGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPVTRPPQP 534
                  P   T  +  T T   P TT S       TT  P P+  P     +P+T PP  
Sbjct: 1458 ISTTTTPPPTTTPSPPTTTPSPPTTTPSPP---TTTTTTPPPTTTPSPPTTTPIT-PPAS 1513

Query: 535  RLTF---VHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAAFSGQPQAVIMTS 591
              T      P P + T   P  P      P   P++       + P      P     T 
Sbjct: 1514 TTTLPPTTTPSPPTTTTTTP-PPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP 1572

Query: 592  GPLKREGMLASTVSQSNVVIA---PAAIARAPGVPEFHSSILVTDLGHGTS---SPPAPV 645
             P        +T      +     P     +P      +    T     T+   +PP   
Sbjct: 1573 PPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTST 1632

Query: 646  SRLFPSTAQDPLGKGEQVPLHGGSPQ-VTVTGPSRDCPNSGQASPCASEQSPSPQSP 701
            + L P+T   P       P    +P   T T PS     +    P  +  SP   +P
Sbjct: 1633 TTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTP 1689



 Score = 53.5 bits (127), Expect = 9e-07
 Identities = 79/375 (21%), Positives = 127/375 (33%), Gaps = 45/375 (12%)

Query: 354  PVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQP- 412
            P P     P    I  TT +     P     P T P             + T+ P   P 
Sbjct: 4050 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4109

Query: 413  ---TDFGPSEPPLSVPQPFL-PVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTF 468
               T   P+  P     P   P+ T   ++P+P P              T + P   PT 
Sbjct: 4110 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4169

Query: 469  HQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALS-- 526
             Q      +    +V T T + T T   P T  S +    +TT +P P ++    + S  
Sbjct: 4170 TQTPTTTPITTTTTV-TPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTS 4228

Query: 527  -PVTR--------PPQPRLTFVHPK-----PVSLTGGRP-KQPHKIVPAPKPEPVSLVLK 571
             P+T         PP   +T   P      P + +GG     P     +P   P      
Sbjct: 4229 SPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTT 4288

Query: 572  NARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSILV 631
             +  AP      P  V  T+          S  + +   ++  +I R  G+  + SS+L+
Sbjct: 4289 GSSSAPT-----PSTVQTTT---------TSAWTPTPTPLSTPSIIRTTGLRPYPSSVLI 4334

Query: 632  TDLGHGTSSPPAPVSRLFPSTAQDPLGKGEQVPLHGGSPQVTVTGPSRDCPNSGQASPCA 691
              + + T    AP   ++  T       G+       S   T+   +  CP++   +P  
Sbjct: 4335 CCVLNDTYY--APGEEVYNGTY------GDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTP 4386

Query: 692  SEQSPSPQSPQNNCS 706
            S+ +P+P  P +  S
Sbjct: 4387 SKSTPTPSKPSSTPS 4401



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 76/377 (20%), Positives = 106/377 (28%), Gaps = 34/377 (9%)

Query: 354  PVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQP- 412
            P P     P    I  TT +     P     P T P             + T+ P   P 
Sbjct: 3866 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3925

Query: 413  ---TDFGPSEPPLSVPQPFL-PVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTF 468
               T   P+  P     P   P+ T   ++P+P P              T + P   PT 
Sbjct: 3926 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3985

Query: 469  HQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPV 528
             Q          P   T T + T T   P  T + +   + TT    P+  P G      
Sbjct: 3986 TQTP-----TTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4037

Query: 529  TRPPQPRLTFVHPKPVSLTGGRPKQ-PHKIVPAPKPEPVSLVLKNARIAPAAFSGQPQAV 587
            T  P    T V P P       P   P        P P     +     P   +     V
Sbjct: 4038 T--PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT---TTV 4092

Query: 588  IMTSGPLKREGMLASTVSQSNVVI---APAAIARAPGVP-EFHSSILVTDLGHGTSSPPA 643
              T  P   +    + ++ +  V     P         P    +++  T    GT +P  
Sbjct: 4093 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4152

Query: 644  PVSRLFPSTAQDPLGKGEQVPLHGG-----------SPQVTVTGPSRDCPNSGQASPCAS 692
                   +    P   G Q P               +P  T TGP      +  A    S
Sbjct: 4153 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTS 4212

Query: 693  EQSPSPQSPQNNCSGKS 709
               P   +PQ + S  S
Sbjct: 4213 NPPPESSTPQTSRSTSS 4229



 Score = 38.5 bits (88), Expect = 0.029
 Identities = 53/246 (21%), Positives = 71/246 (28%), Gaps = 24/246 (9%)

Query: 455  PPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHP 514
            P    +  P+PPT             P   T +   T T   P TT       + TT  P
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPP--ITTTTTP 1448

Query: 515  APSAAPCGLALSPVTRPP--QPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKN 572
             P+  P     +  T PP   P      P P + T   P  P      P P         
Sbjct: 1449 PPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTT---PSPPTTTTTTPPP-------TT 1498

Query: 573  ARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSILVT 632
                P      P A   T  P        +T +       P+     P  P   +    T
Sbjct: 1499 TPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTST----T 1554

Query: 633  DLGHGTSSPPAPVSRLFPSTAQDPLGKGEQVPLHGGSPQVTVTGPSRDCPNSGQASPCAS 692
             L   T+  P P +   P     P       P     P +T T P    P +  + P  +
Sbjct: 1555 TLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTP---SPPTITTTTPP---PTTTPSPPTTT 1608

Query: 693  EQSPSP 698
              +P P
Sbjct: 1609 TTTPPP 1614



 Score = 38.5 bits (88), Expect = 0.029
 Identities = 45/201 (22%), Positives = 63/201 (31%), Gaps = 15/201 (7%)

Query: 348  PASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTED 407
            P + +    +   PP    I  TT +     P     P T P             + T+ 
Sbjct: 1882 PTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 1941

Query: 408  PFIQP----TDFGPSEPPLSVPQP-FLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNP 462
            P   P    T   P+  P     P   P+ T   ++P+P P              T + P
Sbjct: 1942 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2001

Query: 463  PAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCG 522
               PT  Q           + IT T + T T   P  T + +   + TT    P+  P G
Sbjct: 2002 TPTPTGTQ-------TPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTG 2053

Query: 523  LALSPVTRPPQPRLTFVHPKP 543
                  T  P    T V P P
Sbjct: 2054 TQTPTTT--PITTTTTVTPTP 2072



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 45/195 (23%), Positives = 60/195 (30%), Gaps = 15/195 (7%)

Query: 354  PVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQP- 412
            P P     P    I  TT +     P     P T P             + T+ P   P 
Sbjct: 2049 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2108

Query: 413  ---TDFGPSEPPLSVPQP-FLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTF 468
               T   P+  P     P   P+ T   ++P+P P              T + P   PT 
Sbjct: 2109 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2168

Query: 469  HQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPV 528
             Q           + IT T + T T   P  T + +   + TT    P+  P G      
Sbjct: 2169 TQ-------TPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2220

Query: 529  TRPPQPRLTFVHPKP 543
            T  P    T V P P
Sbjct: 2221 T--PITTTTTVTPTP 2233



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 45/195 (23%), Positives = 60/195 (30%), Gaps = 15/195 (7%)

Query: 354  PVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQP- 412
            P P     P    I  TT +     P     P T P             + T+ P   P 
Sbjct: 2210 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2269

Query: 413  ---TDFGPSEPPLSVPQP-FLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTF 468
               T   P+  P     P   P+ T   ++P+P P              T + P   PT 
Sbjct: 2270 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2329

Query: 469  HQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPV 528
             Q           + IT T + T T   P  T + +   + TT    P+  P G      
Sbjct: 2330 TQ-------TPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2381

Query: 529  TRPPQPRLTFVHPKP 543
            T  P    T V P P
Sbjct: 2382 T--PITTTTTVTPTP 2394



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 45/195 (23%), Positives = 60/195 (30%), Gaps = 15/195 (7%)

Query: 354  PVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQP- 412
            P P     P    I  TT +     P     P T P             + T+ P   P 
Sbjct: 2371 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2430

Query: 413  ---TDFGPSEPPLSVPQP-FLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTF 468
               T   P+  P     P   P+ T   ++P+P P              T + P   PT 
Sbjct: 2431 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2490

Query: 469  HQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPV 528
             Q           + IT T + T T   P  T + +   + TT    P+  P G      
Sbjct: 2491 TQ-------TPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2542

Query: 529  TRPPQPRLTFVHPKP 543
            T  P    T V P P
Sbjct: 2543 T--PITTTTTVTPTP 2555



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 45/195 (23%), Positives = 60/195 (30%), Gaps = 15/195 (7%)

Query: 354  PVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQP- 412
            P P     P    I  TT +     P     P T P             + T+ P   P 
Sbjct: 2532 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2591

Query: 413  ---TDFGPSEPPLSVPQP-FLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTF 468
               T   P+  P     P   P+ T   ++P+P P              T + P   PT 
Sbjct: 2592 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2651

Query: 469  HQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPV 528
             Q           + IT T + T T   P  T + +   + TT    P+  P G      
Sbjct: 2652 TQ-------TPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2703

Query: 529  TRPPQPRLTFVHPKP 543
            T  P    T V P P
Sbjct: 2704 T--PITTTTTVTPTP 2716



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 45/195 (23%), Positives = 60/195 (30%), Gaps = 15/195 (7%)

Query: 354  PVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQP- 412
            P P     P    I  TT +     P     P T P             + T+ P   P 
Sbjct: 2693 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2752

Query: 413  ---TDFGPSEPPLSVPQP-FLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTF 468
               T   P+  P     P   P+ T   ++P+P P              T + P   PT 
Sbjct: 2753 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2812

Query: 469  HQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPV 528
             Q           + IT T + T T   P  T + +   + TT    P+  P G      
Sbjct: 2813 TQ-------TPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2864

Query: 529  TRPPQPRLTFVHPKP 543
            T  P    T V P P
Sbjct: 2865 T--PITTTTTVTPTP 2877



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 45/195 (23%), Positives = 60/195 (30%), Gaps = 15/195 (7%)

Query: 354  PVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQP- 412
            P P     P    I  TT +     P     P T P             + T+ P   P 
Sbjct: 2854 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2913

Query: 413  ---TDFGPSEPPLSVPQP-FLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTF 468
               T   P+  P     P   P+ T   ++P+P P              T + P   PT 
Sbjct: 2914 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2973

Query: 469  HQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPV 528
             Q           + IT T + T T   P  T + +   + TT    P+  P G      
Sbjct: 2974 TQ-------TPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3025

Query: 529  TRPPQPRLTFVHPKP 543
            T  P    T V P P
Sbjct: 3026 T--PITTTTTVTPTP 3038



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 45/195 (23%), Positives = 60/195 (30%), Gaps = 15/195 (7%)

Query: 354  PVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQP- 412
            P P     P    I  TT +     P     P T P             + T+ P   P 
Sbjct: 3015 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3074

Query: 413  ---TDFGPSEPPLSVPQP-FLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTF 468
               T   P+  P     P   P+ T   ++P+P P              T + P   PT 
Sbjct: 3075 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3134

Query: 469  HQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPV 528
             Q           + IT T + T T   P  T + +   + TT    P+  P G      
Sbjct: 3135 TQ-------TPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3186

Query: 529  TRPPQPRLTFVHPKP 543
            T  P    T V P P
Sbjct: 3187 T--PITTTTTVTPTP 3199



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 45/195 (23%), Positives = 60/195 (30%), Gaps = 15/195 (7%)

Query: 354  PVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQP- 412
            P P     P    I  TT +     P     P T P             + T+ P   P 
Sbjct: 3176 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3235

Query: 413  ---TDFGPSEPPLSVPQP-FLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTF 468
               T   P+  P     P   P+ T   ++P+P P              T + P   PT 
Sbjct: 3236 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3295

Query: 469  HQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPV 528
             Q           + IT T + T T   P  T + +   + TT    P+  P G      
Sbjct: 3296 TQ-------TPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3347

Query: 529  TRPPQPRLTFVHPKP 543
            T  P    T V P P
Sbjct: 3348 T--PITTTTTVTPTP 3360



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 45/195 (23%), Positives = 60/195 (30%), Gaps = 15/195 (7%)

Query: 354  PVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQP- 412
            P P     P    I  TT +     P     P T P             + T+ P   P 
Sbjct: 3337 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3396

Query: 413  ---TDFGPSEPPLSVPQP-FLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTF 468
               T   P+  P     P   P+ T   ++P+P P              T + P   PT 
Sbjct: 3397 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3456

Query: 469  HQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPV 528
             Q           + IT T + T T   P  T + +   + TT    P+  P G      
Sbjct: 3457 TQ-------TPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3508

Query: 529  TRPPQPRLTFVHPKP 543
            T  P    T V P P
Sbjct: 3509 T--PITTTTTVTPTP 3521



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 45/195 (23%), Positives = 60/195 (30%), Gaps = 15/195 (7%)

Query: 354  PVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQP- 412
            P P     P    I  TT +     P     P T P             + T+ P   P 
Sbjct: 3498 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3557

Query: 413  ---TDFGPSEPPLSVPQP-FLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTF 468
               T   P+  P     P   P+ T   ++P+P P              T + P   PT 
Sbjct: 3558 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3617

Query: 469  HQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPV 528
             Q           + IT T + T T   P  T + +   + TT    P+  P G      
Sbjct: 3618 TQ-------TPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3669

Query: 529  TRPPQPRLTFVHPKP 543
            T  P    T V P P
Sbjct: 3670 T--PITTTTTVTPTP 3682



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 45/195 (23%), Positives = 60/195 (30%), Gaps = 15/195 (7%)

Query: 354  PVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQP- 412
            P P     P    I  TT +     P     P T P             + T+ P   P 
Sbjct: 3659 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3718

Query: 413  ---TDFGPSEPPLSVPQP-FLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTF 468
               T   P+  P     P   P+ T   ++P+P P              T + P   PT 
Sbjct: 3719 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3778

Query: 469  HQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPV 528
             Q           + IT T + T T   P  T + +   + TT    P+  P G      
Sbjct: 3779 TQ-------TPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3830

Query: 529  TRPPQPRLTFVHPKP 543
            T  P    T V P P
Sbjct: 3831 T--PITTTTTVTPTP 3843



 Score = 38.1 bits (87), Expect = 0.038
 Identities = 45/195 (23%), Positives = 60/195 (30%), Gaps = 15/195 (7%)

Query: 354  PVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQP- 412
            P P     P    I  TT +     P     P T P             + T+ P   P 
Sbjct: 3820 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3879

Query: 413  ---TDFGPSEPPLSVPQP-FLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTF 468
               T   P+  P     P   P+ T   ++P+P P              T + P   PT 
Sbjct: 3880 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3939

Query: 469  HQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPV 528
             Q           + IT T + T T   P  T + +   + TT    P+  P G      
Sbjct: 3940 TQ-------TPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3991

Query: 529  TRPPQPRLTFVHPKP 543
            T  P    T V P P
Sbjct: 3992 T--PITTTTTVTPTP 4004



 Score = 34.3 bits (77), Expect = 0.55
 Identities = 32/129 (24%), Positives = 46/129 (35%), Gaps = 17/129 (13%)

Query: 352  SAPVPDPNNPPA------QESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRT 405
            S+P+    +PP         +  P++ + T + P S   P   P+           T+  
Sbjct: 1682 SSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSP----TTTP 1737

Query: 406  EDPFIQPTDFGP---SEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNP 462
              P    T   P   S P  + P P  P  T P  SP     P +P +PL     T    
Sbjct: 1738 SPPTTTMTTLPPTTTSSPLTTTPLP--PSITPPTFSPFSTTTPTTPCVPLC--NWTGWLD 1793

Query: 463  PAPPTFHQP 471
               P FH+P
Sbjct: 1794 SGKPNFHKP 1802



 Score = 30.4 bits (67), Expect = 7.9
 Identities = 32/133 (24%), Positives = 44/133 (33%), Gaps = 10/133 (7%)

Query: 411  QPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTFHQ 470
            QPT    +      P    P+ T   ++P+P P              T + P   PT  Q
Sbjct: 1881 QPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 1940

Query: 471  PQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPVTR 530
                       + IT T + T T   P  T + +   + TT    P+  P G      T 
Sbjct: 1941 -------TPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT- 1991

Query: 531  PPQPRLTFVHPKP 543
             P    T V P P
Sbjct: 1992 -PITTTTTVTPTP 2003


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 103/375 (27%), Positives = 132/375 (35%), Gaps = 75/375 (20%)

Query: 345  SMLPASASAPVPDPNNPPAQESILPTTALP-----TVSLPDSLIAPPTAPSLAHMDEQGC 399
            S LP  AS+P+P PN+ P    +  T ++P      +S+P +L AP +AP          
Sbjct: 1405 SSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTI------- 1457

Query: 400  EHTSRTEDPFIQPTDFGPSEPPL--SVPQPFLPVFTM----PLLSPSPAPPPISPV---L 450
                    P   P     S P L  SV  P  PV       P L+PS A P  S +   L
Sbjct: 1458 --------PISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGL 1509

Query: 451  PLVPPPATALNPP-----APPTFHQPQKFAGVNKAPSVITHTASA------TLTHDAP-- 497
               P  +++  P      AP + H P   + V  A S +   ASA      +  + AP  
Sbjct: 1510 ATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQ 1569

Query: 498  ----ATTFSQSQGLVITTHHPAPSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQ 553
                A   S SQ L       AP AAP    L+P   PP   L  + P P    G  P  
Sbjct: 1570 ASLLAPASSASQALATPL---APMAAPQTAILAPSPAPPLAPLPVLAPSP----GAAPVL 1622

Query: 554  PHKIVPAPKPEPVS---LVLKNARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVV 610
                 P P   P S     L +A   PA       +   T  P      L S  S   + 
Sbjct: 1623 ASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLA 1682

Query: 611  IAPAAIARAPGVPEFHSSILVTDLGHGTSSPP--------APVSRLFPSTAQ-------D 655
            +APA      G     S      LG G    P         P S L P+ AQ        
Sbjct: 1683 LAPALAPTLGG----SSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGP 1738

Query: 656  PLGKGEQVPLHGGSP 670
            PLG  + + L    P
Sbjct: 1739 PLGPTQTLSLAPAPP 1753



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 104/379 (27%), Positives = 140/379 (36%), Gaps = 62/379 (16%)

Query: 348  PASASAPVPDPNNPPAQESILPTTALPTVSLPDSLI--APPTAPSLAHMDEQGCEHTSRT 405
            P +   PVP    P  + S  PT       LP SL+  A P  P L           SR 
Sbjct: 1015 PRAPLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIP--------ASRP 1066

Query: 406  EDPFIQPTDFGPSEPPL-SVPQPFLPVFTMPLLSPSPAPPPISPVLPLVP-PPATALNPP 463
              P + P    P +P   S+PQ    V   PL   S    P +P L L P PPA     P
Sbjct: 1067 PGPVLLP----PLQPNSGSLPQ----VLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSP 1118

Query: 464  APPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGL 523
            APP         G +     +T     T    A ATT S +     TT  PAP+ AP  L
Sbjct: 1119 APPP--------GSSSLLKPLTVPPGYTFP-PAAATTTSTTTATATTTAVPAPTPAPQRL 1169

Query: 524  ALSPVTRPPQP--------RLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARI 575
             LSP  +   P        +L  +  +PV+  GG      +I      +   L L  A++
Sbjct: 1170 ILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQI------QGNKLTLTGAQV 1223

Query: 576  APAAFSGQPQAVIMTSGPLKREGM-LASTVSQSNVVIAPAAIARAPGVPEFHSSILVTDL 634
               A  GQP+       PL+R  + L S   Q +++  PA +A    V        V+ L
Sbjct: 1224 RQLAV-GQPR-------PLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVL 1275

Query: 635  GHGT-SSPPAPVSRLFPSTAQDPLGKGEQVPLHGGSPQVTVTGPSRDCPNSGQASPCASE 693
               T S+ PAP     P  A        QVP    +    V    R  P  G        
Sbjct: 1276 PSSTPSTTPAPTGLSLPLAA-------NQVPPTMVNNTGVVKIVVRQAPRDGLTP--VPP 1326

Query: 694  QSPSPQSPQNNCSGKSDPK 712
             +P+P+ P +      +P+
Sbjct: 1327 LAPAPRPPSSGLPAVLNPR 1345



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 102/384 (26%), Positives = 141/384 (36%), Gaps = 77/384 (20%)

Query: 346  MLPASASA-PVPDPNNP-PAQESILP---------TTALPTVSLPDSLI-----APPTAP 389
            ++PASA A P P   NP PAQ S+L           T L  ++ P + I     APP AP
Sbjct: 1549 LVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAP 1608

Query: 390  SLAHMDEQGCEH---TSRTEDPFIQPTDFG----PSEPPLSVPQPFL-PVFTMPLLS--- 438
                    G      +S+T  P + P+        S  P+  P P L P  T  +L    
Sbjct: 1609 LPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPV 1668

Query: 439  PSPAPPPIS-PVLPLVPPPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAP 497
            PSP P P S   L L P  A  L   +P    Q       N      T T S T     P
Sbjct: 1669 PSPLPSPASTQTLALAPALAPTLGGSSP---SQTLSLGTGNPQGPFPTQTLSLT-----P 1720

Query: 498  ATTFSQSQGLVITTHHPAPSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKI 557
            A++   +    ++     P      L+L+P   PP    + V P P           H +
Sbjct: 1721 ASSLVPTPAQTLSLAPGPPLGPTQTLSLAPA--PPLAPASPVGPAPA----------HTL 1768

Query: 558  VPAPKPEPVSLVLKNARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIA 617
              AP     SL      +APA+     Q + ++  P+   G  A+      + +APA+  
Sbjct: 1769 TLAPASSSASL------LAPASV----QTLTLSPAPVPTLGPAAA----QTLALAPASTQ 1814

Query: 618  RAPGVPEFHSSILVTDLGHGTSSPPAPVSRLFPSTAQDPLGKGEQVPLHGGSPQVTVTGP 677
                 P   +S LV         P   VSRL P +  +P    + + L  G P    T  
Sbjct: 1815 S----PASQASSLVVSASGAAPLPVTMVSRL-PVSKDEP----DTLTLRSGPPSPPSTAT 1865

Query: 678  SRDCPNSGQASPCASEQSPSPQSP 701
            S   P   +  P      P P+SP
Sbjct: 1866 SFGGPRPRRQPP------PPPRSP 1883



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 73/323 (22%), Positives = 116/323 (35%), Gaps = 52/323 (16%)

Query: 434  MPLLSPSPAPPPISPVLPLVPPPATALNP-----PAPPTFHQPQKFAGVNKAPSVITHTA 488
            +P L+P+P PP  S  LP V  P   L P     P   T   P     + +    + H+ 
Sbjct: 1324 VPPLAPAPRPP--SSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSP 1381

Query: 489  SATLTHDAP-ATTFSQSQGLVITTHHPAPSAAPCGL-----ALSPVTRPPQPRLTFVHPK 542
            S  ++  AP A   + S  L + +  P P+++P  +       SPV+      L+   P 
Sbjct: 1382 SPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPI 1441

Query: 543  PVSLTGGRPKQPHKIVPAPKPEPV---------SLVLKNARIAPAA--------FSGQPQ 585
             V  T   P      +P   P  V         S+    A + PAA            P 
Sbjct: 1442 SVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPS 1501

Query: 586  AVIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPE----------FHSSILVTDLG 635
            A  +T G      + +S      +++AP + +  PG+              +S L +   
Sbjct: 1502 ASALTLGLATAPSLSSSQTPGHPLLLAPTS-SHVPGLNSTVAPACSPVLVPASALASPFP 1560

Query: 636  HGTSSPPAPVSRLFPSTAQDPLGKGEQVPLHGGSPQVTVTGPSRD---------CPNSGQ 686
               +  PA  S L P+++          P+   +PQ  +  PS            P+ G 
Sbjct: 1561 SAPNPAPAQASLLAPASSASQALATPLAPM--AAPQTAILAPSPAPPLAPLPVLAPSPGA 1618

Query: 687  ASPCASEQSPSPQSPQNNCSGKS 709
            A   AS Q+P P    ++  G S
Sbjct: 1619 APVLASSQTPVPVMAPSSTPGTS 1641



 Score = 35.8 bits (81), Expect = 0.19
 Identities = 70/274 (25%), Positives = 97/274 (35%), Gaps = 48/274 (17%)

Query: 421  PLSVPQPF--LPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPA--PPTFHQPQKFAG 476
            P+S P P   LPV  +P      +PPP S + P   P  T   PPA  PP  H P     
Sbjct: 2467 PISAPNPITILPVHILP------SPPPPSQIPPCSSPACTP--PPACTPPPAHTP----- 2513

Query: 477  VNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPS------AAPCGLALSPVTR 530
                      T S+ L    P+   S S   +     P         A+P  L L+ V  
Sbjct: 2514 --PPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVAS 2571

Query: 531  PPQPRLTFVHPK---PVSLTGGRPKQPHKIVPAPK------PEPVSLVLKNARIAPAAFS 581
                 L+ V PK   PV++         +I+P  +      P   SL L+   I      
Sbjct: 2572 SETSSLSLVPPKDLLPVAV---------EILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQ 2622

Query: 582  GQPQAVIMTSGPLKREG-MLASTVSQSNVVIAPAAIARAPGVPE----FHSSILVTDLGH 636
              P +   T+  +  EG  L   VS+SN +  P + A    + E      +S  +T+   
Sbjct: 2623 EAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKT 2682

Query: 637  GTSSPPAPVSRLFPSTAQDPLGKGEQVPLHGGSP 670
             TSSP  P   +    A             G SP
Sbjct: 2683 PTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSP 2716


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 94/366 (25%), Positives = 131/366 (35%), Gaps = 48/366 (13%)

Query: 348  PASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTED 407
            PAS +A VP P  P +  + +PT   PT   P + + PP  P+         E    T  
Sbjct: 1000 PASPAAAVPTPEEPTSPAAAVPTPEEPT--SPAAAVPPPEEPTSPAAAVPTPEEP--TSP 1055

Query: 408  PFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPA-PPPISPVLP--LVPPPATALNPPA 464
                PT   P+ P  +VP P  P       SP+ A P P  P  P   VP P    +P A
Sbjct: 1056 AAAVPTPEEPTSPAAAVPTPEEPT------SPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1109

Query: 465  P-PTFHQPQKFAGVNKAPSVITHTASATLTHDAPA------TTFSQSQGLVITTHHPAPS 517
              PT  +P   A     P      A+A  T + PA       T  +S    +    P  S
Sbjct: 1110 AVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEES 1169

Query: 518  AAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAP 577
            A+P     +P         +F     V  T   P  P   VP P           A +A 
Sbjct: 1170 ASPAAAVPTPA-----ESASFA---AVVATLEEPTSPAASVPTPA----------AMVAT 1211

Query: 578  AAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSILVT--DLG 635
                  P A + TS   +    LA+ VS      +PAA       P   ++ ++T  +L 
Sbjct: 1212 LEEFTSPAASVPTS---EEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELS 1268

Query: 636  HGTSSPPAPVSRLFPSTA----QDPLGKGEQVPLHGGSPQVTVTGPSRDCPN-SGQASPC 690
               +S P P     P+ A    ++P      VP    +     + P+ + P     A P 
Sbjct: 1269 SPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPP 1328

Query: 691  ASEQSP 696
              E SP
Sbjct: 1329 MEEVSP 1334



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 94/378 (24%), Positives = 134/378 (35%), Gaps = 57/378 (15%)

Query: 348  PASASAPVPDPNNP--------PAQESILPTTALPTVSLPDSLIA------PPTAPSLAH 393
            P S +A VP P  P        P +E   P  A+PT   P S  A       PT+P+ A 
Sbjct: 1013 PTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1072

Query: 394  MDEQGCEHTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLV 453
               +       T      PT   P+ P  +VP P  P  T P  +      P SP   + 
Sbjct: 1073 PTPE-----EPTSPAAAVPTPEEPTSPAAAVPTPEEP--TSPAAAVPTPEEPASPAAAVP 1125

Query: 454  PPPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHH 513
             P   A    A PT  +P        AP+V T   SA+     P    S S    + T  
Sbjct: 1126 TPEEPASPAAAVPTPEEP-----AFPAPAVPTPEESASAAVAVPTPEESASPAAAVPT-- 1178

Query: 514  PAPSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNA 573
            PA SA+     ++ +  P  P  +   P  +  T      P   VP  + EP SL    A
Sbjct: 1179 PAESAS-FAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSE-EPASLA---A 1233

Query: 574  RIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSILVTD 633
             ++       P A + T   L+     A+ V     + +PAA    P  P    +  V++
Sbjct: 1234 AVSNPEEPTSPAAAVPT---LEEPTSSAAAVLTPEELSSPAASVPTPEEPA-SPAAAVSN 1289

Query: 634  LGHGTS----------------SPPAPVSRLFPSTAQDPLGKGEQVPLHGGSPQVTVTGP 677
            L    S                S P P     P+ A  P+ +   +    G P + V+  
Sbjct: 1290 LEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPI----GVPFLGVSAH 1345

Query: 678  SRDCPNSGQASPCASEQS 695
            +   P S + +P   E S
Sbjct: 1346 TDSVPISEEGTPVLEEAS 1363



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 46/200 (23%), Positives = 80/200 (40%), Gaps = 21/200 (10%)

Query: 333  QDLFSSSRSIFGSMLPASASAPVPDPNNPPAQESILPTTALPT-----VSLPDSLIAPPT 387
            ++  S + S+  S  PAS +A V +P  P +  + +PT   PT     V  P+ L +P  
Sbjct: 1213 EEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAA 1272

Query: 388  APSLAHMDEQGCEHTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPIS 447
            +              S  E+P   P    P+    ++P   +P   +P + P+ A PP+ 
Sbjct: 1273 SVPTPEEPASPAAAVSNLEEP-ASPAAAVPTPEVAAIPAASVPTPEVPAI-PAAAVPPME 1330

Query: 448  PVLPL-VPPPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASAT---LTHDAPATTFSQ 503
             V P+ VP    + +  + P          +++  + +   AS+T   +  D  +  F  
Sbjct: 1331 EVSPIGVPFLGVSAHTDSVP----------ISEEGTPVLEEASSTGMWIKEDLDSLVFGI 1380

Query: 504  SQGLVITTHHPAPSAAPCGL 523
             +      H   P AA  GL
Sbjct: 1381 KEVTSTVLHGKVPLAATAGL 1400



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 86/333 (25%), Positives = 110/333 (33%), Gaps = 67/333 (20%)

Query: 417  PSEPPLSVPQPFLPVFTMPLLSPSPA-PPPISPVLPLVPPPATALNPP--------APPT 467
            P+ P  +VP P  P       SP+ A P P  P       PA A+ PP        A PT
Sbjct: 1000 PASPAAAVPTPEEPT------SPAAAVPTPEEPT-----SPAAAVPPPEEPTSPAAAVPT 1048

Query: 468  FHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGL---A 524
              +P   A     P   T  A+A  T + P    +     V T   P   AA        
Sbjct: 1049 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEP----TSPAAAVPTPEEPTSPAAAVPTPEEP 1104

Query: 525  LSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPK---------PEPVSLVLKNARI 575
             SP    P P      P     T   P  P   VP P+         P P         +
Sbjct: 1105 TSPAAAVPTPEEP-ASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAV 1163

Query: 576  APAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSILVTDLG 635
                 S  P A + T          A+ V+      +PAA    P       + +V  L 
Sbjct: 1164 PTPEESASPAAAVPTPA---ESASFAAVVATLEEPTSPAASVPTP-------AAMVATLE 1213

Query: 636  HGTSSPPAPVSRLFPSTAQDPLGKGEQV--PLHGGSPQVTVTGPSRDCPNSGQA------ 687
              T SP A V      T+++P      V  P    SP   V  P+ + P S  A      
Sbjct: 1214 EFT-SPAASV-----PTSEEPASLAAAVSNPEEPTSPAAAV--PTLEEPTSSAAAVLTPE 1265

Query: 688  ---SPCASEQSP-SPQSPQNNCSGKSDPKNVAA 716
               SP AS  +P  P SP    S   +P + AA
Sbjct: 1266 ELSSPAASVPTPEEPASPAAAVSNLEEPASPAA 1298


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 63.5 bits (153), Expect = 8e-10
 Identities = 76/330 (23%), Positives = 114/330 (34%), Gaps = 22/330 (6%)

Query: 383 IAPPTAPSLAHMDEQGCEHTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPA 442
           I   +A  LA   +   + T + E     P    P EP  + P+   P  T P   P+P 
Sbjct: 179 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE--PASTTPK-EPTPT 235

Query: 443 PPPISPVLPLVPPPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFS 502
               +P  P  P P T  + P  P   +P        AP+     A  T    AP TT S
Sbjct: 236 TIKSAPTTPKEPAPTTTKSAPTTPK--EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 293

Query: 503 ----QSQGLVITTHHPAPSA----APCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQP 554
                 +    T   PAP+     AP        T P +P  T   P P +     P  P
Sbjct: 294 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 353

Query: 555 HKIVPAPKPEPVSLVLKNARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPA 614
            K  P    EP     K     PA  + +  +      P       A T ++     AP 
Sbjct: 354 KKPAPTTPKEPAPTTPKE----PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP---APT 406

Query: 615 AIARAPGVPEFHSSILVTDLGHGTSSPPAPVS--RLFPSTAQDPLGKGEQVPLHGGSPQV 672
               AP  P+  S     +    T   PAP +  +  P+T ++P     + P    + + 
Sbjct: 407 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 466

Query: 673 TVTGPSRDCPNSGQASPCASEQSPSPQSPQ 702
             T P    P + + +   + +  +P +P+
Sbjct: 467 APTTPKEPAPTTPKETAPTTPKKLTPTTPE 496



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 89/407 (21%), Positives = 122/407 (29%), Gaps = 31/407 (7%)

Query: 348 PASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPT-APSLAHMDEQGCEHTSRTE 406
           PA  +   P P  P       P    PT +   S   P   AP+         +  + T 
Sbjct: 348 PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT 407

Query: 407 DPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVP--PPATALNPPA 464
                 T   PS      P P  P    P     PAP       P  P  P  T    PA
Sbjct: 408 TKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 467

Query: 465 PPTFHQPQKFAGVNKAPSV------ITHTASATLTHDAPATTFSQ-------SQGLVITT 511
           P T  +P        AP+        T    A  T + PA T  +        +    T 
Sbjct: 468 PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 527

Query: 512 HHPAP----SAAPCGLALSPVTRPPQPR-LTFVHPKPVSLTGGRPKQPHKIVPAPKPEPV 566
             PAP    +AAP        T P +P   T   P P +     P  P    P    EP 
Sbjct: 528 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA 587

Query: 567 SLVLKN---ARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIAR-APGV 622
               K      +AP               P   +G   +T  +     AP      AP  
Sbjct: 588 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP----APTTPKEPAPTT 643

Query: 623 PEFHSSILVTDLGHGTSSPPAPVSRLFPSTAQDPLGKGEQVPLHGGSPQVTVTGPSRDCP 682
           P+  +   + +    T   PAP   L P+T + P       P      +   T P    P
Sbjct: 644 PKGTAPTTLKEPAPTTPKKPAP-KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 702

Query: 683 NS-GQASPCASEQSPSPQSPQNNCSGKSDPKNVAALKNRQMKHISAE 728
            +  + +P   E  P   S  +  +   +P  +    +     +SAE
Sbjct: 703 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 749



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 91/376 (24%), Positives = 121/376 (32%), Gaps = 54/376 (14%)

Query: 348 PASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTED 407
           P +   P P     PA     PTT   T       + P T   LA    +    T+  E 
Sbjct: 460 PTTTKKPAPTTPKEPA-----PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE- 513

Query: 408 PFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPIS-PVLPLVPPPATALNPPAPP 466
             + PT   P EP  + P+            P+P  P  + P  P  P P T    PAP 
Sbjct: 514 --LAPTT--PEEPTPTTPE-----------EPAPTTPKAAAPNTPKEPAPTTP-KEPAPT 557

Query: 467 TFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALS 526
           T  +P        AP+    TA  TL   AP            T   PAP        L+
Sbjct: 558 TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT-----------TPKKPAPK------ELA 600

Query: 527 PVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAAFSGQPQA 586
           P T       T   P P +  G  P  P +  P    EP     K    AP     +  A
Sbjct: 601 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT--APTTL--KEPA 656

Query: 587 VIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSILVTDLGHGTSSPPAPVS 646
                 P  +E  LA T ++     +  +   AP  P+  +     +    T   PAP +
Sbjct: 657 PTTPKKPAPKE--LAPTTTKGPT--STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT 712

Query: 647 RLFPSTAQDPLGKGEQVPLHGGSPQVTVTGPSRDCPN-SGQASPCASEQSP-SPQSPQNN 704
              P T   P       P     P      P    P  S + +P A E SP  P  P   
Sbjct: 713 ---PET-PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTK 768

Query: 705 CSGKSDPKNVAALKNR 720
               + P+     K++
Sbjct: 769 TPAATKPEMTTTAKDK 784



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 92/388 (23%), Positives = 129/388 (33%), Gaps = 47/388 (12%)

Query: 348 PASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTED 407
           PA  +   P P  P       P    PT   P    AP T    A    +    T+  E 
Sbjct: 309 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP----APTTPKEPAPTAPKKPAPTTPKEP 364

Query: 408 PFIQPTDFGPS---EPPLSVPQPFLPVFT--MPLLSPSPAPPPI--SPVLPLVPPPATAL 460
               P +  P+   EP  + P+   P  T   P  +  PAP     +P  P  P P T  
Sbjct: 365 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT- 423

Query: 461 NPPAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAP---- 516
             PAP T  +P        AP+     A  T    AP TT    +    T   PAP    
Sbjct: 424 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT---KKPAPTTPKEPAPTTPK 480

Query: 517 -SAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARI 575
            +A      L+P T       T   P P +     P  P +  P    EP     K    
Sbjct: 481 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK---- 536

Query: 576 APAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSILVTDLG 635
           A A  + +  A      P       A T  +      P     AP  P+  +   + +  
Sbjct: 537 AAAPNTPKEPAPTTPKEP-------APTTPKEPAPTTPK--ETAPTTPKGTAPTTLKEPA 587

Query: 636 HGTSSPPAPVSRLFPSTAQDPLG----KGEQVPLHGGSP----QVTVTGPSRDCPNSGQA 687
             T   PAP   L P+T ++P      K       G +P    +   T P    P + + 
Sbjct: 588 PTTPKKPAP-KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG 646

Query: 688 SPCASEQSPSPQSPQNNCSGKSDPKNVA 715
           +   + + P+P +P+     K  PK +A
Sbjct: 647 TAPTTLKEPAPTTPK-----KPAPKELA 669



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 46/216 (21%), Positives = 74/216 (34%), Gaps = 16/216 (7%)

Query: 355 VPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQPTD 414
           VP    P A +  + TTA    +  D    P T  +   M ++    T +T +  I  T 
Sbjct: 764 VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 823

Query: 415 FGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVL---PLVPPPATALNPP-----APP 466
              +        PF  + T+   + +P        +    ++  P     P      +  
Sbjct: 824 TQVTSTTTQDTTPF-KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 882

Query: 467 TFHQPQKFAGVNKAPSVITHTAS-ATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLAL 525
           T  +PQK     KAP   T T    T+       T    + +  T     P++      L
Sbjct: 883 TTPKPQK---PTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAML 939

Query: 526 SPVTRP---PQPRLTFVHPKPVSLTGGRPKQPHKIV 558
              TRP   P  +L  V+PK     G   + PH ++
Sbjct: 940 QTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 975



 Score = 30.8 bits (68), Expect = 6.1
 Identities = 49/239 (20%), Positives = 75/239 (31%), Gaps = 21/239 (8%)

Query: 356 PDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSR-TEDPFIQPTD 414
           P P  P       P T  PT S    +  P T      + +   E T   + +P  +  +
Sbjct: 700 PAPTTPKKPAPTTPETPPPTTS---EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE 756

Query: 415 FGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTFHQPQKF 474
             P EP   VP    P  T P ++ +         L   P   TA       T    +K 
Sbjct: 757 NSPKEP--GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKT 814

Query: 475 AGVNKAPSVITHTASATLTHDAP-----------ATTFSQSQGLVITT---HHPAPSAAP 520
              +K  +  T   S T     P           A   + ++  + TT   + P  +A P
Sbjct: 815 TE-SKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKP 873

Query: 521 CGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAA 579
              A +     P+P+     PK  + T      P    P   P P  +      + P +
Sbjct: 874 KDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTS 932


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 63.5 bits (153), Expect = 8e-10
 Identities = 76/330 (23%), Positives = 114/330 (34%), Gaps = 22/330 (6%)

Query: 383 IAPPTAPSLAHMDEQGCEHTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPA 442
           I   +A  LA   +   + T + E     P    P EP  + P+   P  T P   P+P 
Sbjct: 220 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE--PASTTPK-EPTPT 276

Query: 443 PPPISPVLPLVPPPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFS 502
               +P  P  P P T  + P  P   +P        AP+     A  T    AP TT S
Sbjct: 277 TIKSAPTTPKEPAPTTTKSAPTTPK--EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 334

Query: 503 ----QSQGLVITTHHPAPSA----APCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQP 554
                 +    T   PAP+     AP        T P +P  T   P P +     P  P
Sbjct: 335 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 394

Query: 555 HKIVPAPKPEPVSLVLKNARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPA 614
            K  P    EP     K     PA  + +  +      P       A T ++     AP 
Sbjct: 395 KKPAPTTPKEPAPTTPKE----PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP---APT 447

Query: 615 AIARAPGVPEFHSSILVTDLGHGTSSPPAPVS--RLFPSTAQDPLGKGEQVPLHGGSPQV 672
               AP  P+  S     +    T   PAP +  +  P+T ++P     + P    + + 
Sbjct: 448 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 507

Query: 673 TVTGPSRDCPNSGQASPCASEQSPSPQSPQ 702
             T P    P + + +   + +  +P +P+
Sbjct: 508 APTTPKEPAPTTPKETAPTTPKKLTPTTPE 537



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 89/407 (21%), Positives = 122/407 (29%), Gaps = 31/407 (7%)

Query: 348 PASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPT-APSLAHMDEQGCEHTSRTE 406
           PA  +   P P  P       P    PT +   S   P   AP+         +  + T 
Sbjct: 389 PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT 448

Query: 407 DPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVP--PPATALNPPA 464
                 T   PS      P P  P    P     PAP       P  P  P  T    PA
Sbjct: 449 TKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 508

Query: 465 PPTFHQPQKFAGVNKAPSV------ITHTASATLTHDAPATTFSQ-------SQGLVITT 511
           P T  +P        AP+        T    A  T + PA T  +        +    T 
Sbjct: 509 PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 568

Query: 512 HHPAP----SAAPCGLALSPVTRPPQPR-LTFVHPKPVSLTGGRPKQPHKIVPAPKPEPV 566
             PAP    +AAP        T P +P   T   P P +     P  P    P    EP 
Sbjct: 569 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA 628

Query: 567 SLVLKN---ARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIAR-APGV 622
               K      +AP               P   +G   +T  +     AP      AP  
Sbjct: 629 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP----APTTPKEPAPTT 684

Query: 623 PEFHSSILVTDLGHGTSSPPAPVSRLFPSTAQDPLGKGEQVPLHGGSPQVTVTGPSRDCP 682
           P+  +   + +    T   PAP   L P+T + P       P      +   T P    P
Sbjct: 685 PKGTAPTTLKEPAPTTPKKPAP-KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 743

Query: 683 NS-GQASPCASEQSPSPQSPQNNCSGKSDPKNVAALKNRQMKHISAE 728
            +  + +P   E  P   S  +  +   +P  +    +     +SAE
Sbjct: 744 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 790



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 91/376 (24%), Positives = 121/376 (32%), Gaps = 54/376 (14%)

Query: 348 PASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTED 407
           P +   P P     PA     PTT   T       + P T   LA    +    T+  E 
Sbjct: 501 PTTTKKPAPTTPKEPA-----PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE- 554

Query: 408 PFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPIS-PVLPLVPPPATALNPPAPP 466
             + PT   P EP  + P+            P+P  P  + P  P  P P T    PAP 
Sbjct: 555 --LAPTT--PEEPTPTTPE-----------EPAPTTPKAAAPNTPKEPAPTTP-KEPAPT 598

Query: 467 TFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALS 526
           T  +P        AP+    TA  TL   AP            T   PAP        L+
Sbjct: 599 TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT-----------TPKKPAPK------ELA 641

Query: 527 PVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAAFSGQPQA 586
           P T       T   P P +  G  P  P +  P    EP     K    AP     +  A
Sbjct: 642 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT--APTTL--KEPA 697

Query: 587 VIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSILVTDLGHGTSSPPAPVS 646
                 P  +E  LA T ++     +  +   AP  P+  +     +    T   PAP +
Sbjct: 698 PTTPKKPAPKE--LAPTTTKGPT--STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT 753

Query: 647 RLFPSTAQDPLGKGEQVPLHGGSPQVTVTGPSRDCPN-SGQASPCASEQSP-SPQSPQNN 704
              P T   P       P     P      P    P  S + +P A E SP  P  P   
Sbjct: 754 ---PET-PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTK 809

Query: 705 CSGKSDPKNVAALKNR 720
               + P+     K++
Sbjct: 810 TPAATKPEMTTTAKDK 825



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 92/388 (23%), Positives = 129/388 (33%), Gaps = 47/388 (12%)

Query: 348 PASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTED 407
           PA  +   P P  P       P    PT   P    AP T    A    +    T+  E 
Sbjct: 350 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP----APTTPKEPAPTAPKKPAPTTPKEP 405

Query: 408 PFIQPTDFGPS---EPPLSVPQPFLPVFT--MPLLSPSPAPPPI--SPVLPLVPPPATAL 460
               P +  P+   EP  + P+   P  T   P  +  PAP     +P  P  P P T  
Sbjct: 406 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT- 464

Query: 461 NPPAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAP---- 516
             PAP T  +P        AP+     A  T    AP TT    +    T   PAP    
Sbjct: 465 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT---KKPAPTTPKEPAPTTPK 521

Query: 517 -SAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARI 575
            +A      L+P T       T   P P +     P  P +  P    EP     K    
Sbjct: 522 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK---- 577

Query: 576 APAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSILVTDLG 635
           A A  + +  A      P       A T  +      P     AP  P+  +   + +  
Sbjct: 578 AAAPNTPKEPAPTTPKEP-------APTTPKEPAPTTPK--ETAPTTPKGTAPTTLKEPA 628

Query: 636 HGTSSPPAPVSRLFPSTAQDPLG----KGEQVPLHGGSP----QVTVTGPSRDCPNSGQA 687
             T   PAP   L P+T ++P      K       G +P    +   T P    P + + 
Sbjct: 629 PTTPKKPAP-KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG 687

Query: 688 SPCASEQSPSPQSPQNNCSGKSDPKNVA 715
           +   + + P+P +P+     K  PK +A
Sbjct: 688 TAPTTLKEPAPTTPK-----KPAPKELA 710



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 46/216 (21%), Positives = 74/216 (34%), Gaps = 16/216 (7%)

Query: 355  VPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQPTD 414
            VP    P A +  + TTA    +  D    P T  +   M ++    T +T +  I  T 
Sbjct: 805  VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 864

Query: 415  FGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVL---PLVPPPATALNPP-----APP 466
               +        PF  + T+   + +P        +    ++  P     P      +  
Sbjct: 865  TQVTSTTTQDTTPF-KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 923

Query: 467  TFHQPQKFAGVNKAPSVITHTAS-ATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLAL 525
            T  +PQK     KAP   T T    T+       T    + +  T     P++      L
Sbjct: 924  TTPKPQK---PTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAML 980

Query: 526  SPVTRP---PQPRLTFVHPKPVSLTGGRPKQPHKIV 558
               TRP   P  +L  V+PK     G   + PH ++
Sbjct: 981  QTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 1016



 Score = 30.8 bits (68), Expect = 6.1
 Identities = 49/239 (20%), Positives = 75/239 (31%), Gaps = 21/239 (8%)

Query: 356 PDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSR-TEDPFIQPTD 414
           P P  P       P T  PT S    +  P T      + +   E T   + +P  +  +
Sbjct: 741 PAPTTPKKPAPTTPETPPPTTS---EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE 797

Query: 415 FGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTFHQPQKF 474
             P EP   VP    P  T P ++ +         L   P   TA       T    +K 
Sbjct: 798 NSPKEP--GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKT 855

Query: 475 AGVNKAPSVITHTASATLTHDAP-----------ATTFSQSQGLVITT---HHPAPSAAP 520
              +K  +  T   S T     P           A   + ++  + TT   + P  +A P
Sbjct: 856 TE-SKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKP 914

Query: 521 CGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAA 579
              A +     P+P+     PK  + T      P    P   P P  +      + P +
Sbjct: 915 KDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTS 973


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 63.5 bits (153), Expect = 8e-10
 Identities = 76/330 (23%), Positives = 114/330 (34%), Gaps = 22/330 (6%)

Query: 383 IAPPTAPSLAHMDEQGCEHTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPA 442
           I   +A  LA   +   + T + E     P    P EP  + P+   P  T P   P+P 
Sbjct: 272 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE--PASTTPK-EPTPT 328

Query: 443 PPPISPVLPLVPPPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFS 502
               +P  P  P P T  + P  P   +P        AP+     A  T    AP TT S
Sbjct: 329 TIKSAPTTPKEPAPTTTKSAPTTPK--EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 386

Query: 503 ----QSQGLVITTHHPAPSA----APCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQP 554
                 +    T   PAP+     AP        T P +P  T   P P +     P  P
Sbjct: 387 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 446

Query: 555 HKIVPAPKPEPVSLVLKNARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPA 614
            K  P    EP     K     PA  + +  +      P       A T ++     AP 
Sbjct: 447 KKPAPTTPKEPAPTTPKE----PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP---APT 499

Query: 615 AIARAPGVPEFHSSILVTDLGHGTSSPPAPVS--RLFPSTAQDPLGKGEQVPLHGGSPQV 672
               AP  P+  S     +    T   PAP +  +  P+T ++P     + P    + + 
Sbjct: 500 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 559

Query: 673 TVTGPSRDCPNSGQASPCASEQSPSPQSPQ 702
             T P    P + + +   + +  +P +P+
Sbjct: 560 APTTPKEPAPTTPKETAPTTPKKLTPTTPE 589



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 89/407 (21%), Positives = 122/407 (29%), Gaps = 31/407 (7%)

Query: 348 PASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPT-APSLAHMDEQGCEHTSRTE 406
           PA  +   P P  P       P    PT +   S   P   AP+         +  + T 
Sbjct: 441 PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT 500

Query: 407 DPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVP--PPATALNPPA 464
                 T   PS      P P  P    P     PAP       P  P  P  T    PA
Sbjct: 501 TKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 560

Query: 465 PPTFHQPQKFAGVNKAPSV------ITHTASATLTHDAPATTFSQ-------SQGLVITT 511
           P T  +P        AP+        T    A  T + PA T  +        +    T 
Sbjct: 561 PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 620

Query: 512 HHPAP----SAAPCGLALSPVTRPPQPR-LTFVHPKPVSLTGGRPKQPHKIVPAPKPEPV 566
             PAP    +AAP        T P +P   T   P P +     P  P    P    EP 
Sbjct: 621 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA 680

Query: 567 SLVLKN---ARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIAR-APGV 622
               K      +AP               P   +G   +T  +     AP      AP  
Sbjct: 681 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP----APTTPKEPAPTT 736

Query: 623 PEFHSSILVTDLGHGTSSPPAPVSRLFPSTAQDPLGKGEQVPLHGGSPQVTVTGPSRDCP 682
           P+  +   + +    T   PAP   L P+T + P       P      +   T P    P
Sbjct: 737 PKGTAPTTLKEPAPTTPKKPAP-KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 795

Query: 683 NS-GQASPCASEQSPSPQSPQNNCSGKSDPKNVAALKNRQMKHISAE 728
            +  + +P   E  P   S  +  +   +P  +    +     +SAE
Sbjct: 796 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 842



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 91/376 (24%), Positives = 121/376 (32%), Gaps = 54/376 (14%)

Query: 348 PASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTED 407
           P +   P P     PA     PTT   T       + P T   LA    +    T+  E 
Sbjct: 553 PTTTKKPAPTTPKEPA-----PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE- 606

Query: 408 PFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPIS-PVLPLVPPPATALNPPAPP 466
             + PT   P EP  + P+            P+P  P  + P  P  P P T    PAP 
Sbjct: 607 --LAPTT--PEEPTPTTPE-----------EPAPTTPKAAAPNTPKEPAPTTP-KEPAPT 650

Query: 467 TFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALS 526
           T  +P        AP+    TA  TL   AP            T   PAP        L+
Sbjct: 651 TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT-----------TPKKPAPK------ELA 693

Query: 527 PVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAAFSGQPQA 586
           P T       T   P P +  G  P  P +  P    EP     K    AP     +  A
Sbjct: 694 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT--APTTL--KEPA 749

Query: 587 VIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSILVTDLGHGTSSPPAPVS 646
                 P  +E  LA T ++     +  +   AP  P+  +     +    T   PAP +
Sbjct: 750 PTTPKKPAPKE--LAPTTTKGPT--STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT 805

Query: 647 RLFPSTAQDPLGKGEQVPLHGGSPQVTVTGPSRDCPN-SGQASPCASEQSP-SPQSPQNN 704
              P T   P       P     P      P    P  S + +P A E SP  P  P   
Sbjct: 806 ---PET-PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTK 861

Query: 705 CSGKSDPKNVAALKNR 720
               + P+     K++
Sbjct: 862 TPAATKPEMTTTAKDK 877



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 92/388 (23%), Positives = 129/388 (33%), Gaps = 47/388 (12%)

Query: 348 PASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTED 407
           PA  +   P P  P       P    PT   P    AP T    A    +    T+  E 
Sbjct: 402 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP----APTTPKEPAPTAPKKPAPTTPKEP 457

Query: 408 PFIQPTDFGPS---EPPLSVPQPFLPVFT--MPLLSPSPAPPPI--SPVLPLVPPPATAL 460
               P +  P+   EP  + P+   P  T   P  +  PAP     +P  P  P P T  
Sbjct: 458 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT- 516

Query: 461 NPPAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAP---- 516
             PAP T  +P        AP+     A  T    AP TT    +    T   PAP    
Sbjct: 517 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT---KKPAPTTPKEPAPTTPK 573

Query: 517 -SAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARI 575
            +A      L+P T       T   P P +     P  P +  P    EP     K    
Sbjct: 574 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK---- 629

Query: 576 APAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSILVTDLG 635
           A A  + +  A      P       A T  +      P     AP  P+  +   + +  
Sbjct: 630 AAAPNTPKEPAPTTPKEP-------APTTPKEPAPTTPK--ETAPTTPKGTAPTTLKEPA 680

Query: 636 HGTSSPPAPVSRLFPSTAQDPLG----KGEQVPLHGGSP----QVTVTGPSRDCPNSGQA 687
             T   PAP   L P+T ++P      K       G +P    +   T P    P + + 
Sbjct: 681 PTTPKKPAP-KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG 739

Query: 688 SPCASEQSPSPQSPQNNCSGKSDPKNVA 715
           +   + + P+P +P+     K  PK +A
Sbjct: 740 TAPTTLKEPAPTTPK-----KPAPKELA 762



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 46/216 (21%), Positives = 74/216 (34%), Gaps = 16/216 (7%)

Query: 355  VPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQPTD 414
            VP    P A +  + TTA    +  D    P T  +   M ++    T +T +  I  T 
Sbjct: 857  VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 916

Query: 415  FGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVL---PLVPPPATALNPP-----APP 466
               +        PF  + T+   + +P        +    ++  P     P      +  
Sbjct: 917  TQVTSTTTQDTTPF-KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 975

Query: 467  TFHQPQKFAGVNKAPSVITHTAS-ATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLAL 525
            T  +PQK     KAP   T T    T+       T    + +  T     P++      L
Sbjct: 976  TTPKPQK---PTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAML 1032

Query: 526  SPVTRP---PQPRLTFVHPKPVSLTGGRPKQPHKIV 558
               TRP   P  +L  V+PK     G   + PH ++
Sbjct: 1033 QTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 1068



 Score = 30.8 bits (68), Expect = 6.1
 Identities = 49/239 (20%), Positives = 75/239 (31%), Gaps = 21/239 (8%)

Query: 356  PDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSR-TEDPFIQPTD 414
            P P  P       P T  PT S    +  P T      + +   E T   + +P  +  +
Sbjct: 793  PAPTTPKKPAPTTPETPPPTTS---EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE 849

Query: 415  FGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTFHQPQKF 474
              P EP   VP    P  T P ++ +         L   P   TA       T    +K 
Sbjct: 850  NSPKEP--GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKT 907

Query: 475  AGVNKAPSVITHTASATLTHDAP-----------ATTFSQSQGLVITT---HHPAPSAAP 520
               +K  +  T   S T     P           A   + ++  + TT   + P  +A P
Sbjct: 908  TE-SKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKP 966

Query: 521  CGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAA 579
               A +     P+P+     PK  + T      P    P   P P  +      + P +
Sbjct: 967  KDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTS 1025


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 63.5 bits (153), Expect = 8e-10
 Identities = 76/330 (23%), Positives = 114/330 (34%), Gaps = 22/330 (6%)

Query: 383 IAPPTAPSLAHMDEQGCEHTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPA 442
           I   +A  LA   +   + T + E     P    P EP  + P+   P  T P   P+P 
Sbjct: 313 IEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE--PASTTPK-EPTPT 369

Query: 443 PPPISPVLPLVPPPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFS 502
               +P  P  P P T  + P  P   +P        AP+     A  T    AP TT S
Sbjct: 370 TIKSAPTTPKEPAPTTTKSAPTTPK--EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 427

Query: 503 ----QSQGLVITTHHPAPSA----APCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQP 554
                 +    T   PAP+     AP        T P +P  T   P P +     P  P
Sbjct: 428 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 487

Query: 555 HKIVPAPKPEPVSLVLKNARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPA 614
            K  P    EP     K     PA  + +  +      P       A T ++     AP 
Sbjct: 488 KKPAPTTPKEPAPTTPKE----PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP---APT 540

Query: 615 AIARAPGVPEFHSSILVTDLGHGTSSPPAPVS--RLFPSTAQDPLGKGEQVPLHGGSPQV 672
               AP  P+  S     +    T   PAP +  +  P+T ++P     + P    + + 
Sbjct: 541 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKP 600

Query: 673 TVTGPSRDCPNSGQASPCASEQSPSPQSPQ 702
             T P    P + + +   + +  +P +P+
Sbjct: 601 APTTPKEPAPTTPKETAPTTPKKLTPTTPE 630



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 89/407 (21%), Positives = 122/407 (29%), Gaps = 31/407 (7%)

Query: 348 PASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPT-APSLAHMDEQGCEHTSRTE 406
           PA  +   P P  P       P    PT +   S   P   AP+         +  + T 
Sbjct: 482 PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT 541

Query: 407 DPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVP--PPATALNPPA 464
                 T   PS      P P  P    P     PAP       P  P  P  T    PA
Sbjct: 542 TKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 601

Query: 465 PPTFHQPQKFAGVNKAPSV------ITHTASATLTHDAPATTFSQ-------SQGLVITT 511
           P T  +P        AP+        T    A  T + PA T  +        +    T 
Sbjct: 602 PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 661

Query: 512 HHPAP----SAAPCGLALSPVTRPPQPR-LTFVHPKPVSLTGGRPKQPHKIVPAPKPEPV 566
             PAP    +AAP        T P +P   T   P P +     P  P    P    EP 
Sbjct: 662 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA 721

Query: 567 SLVLKN---ARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIAR-APGV 622
               K      +AP               P   +G   +T  +     AP      AP  
Sbjct: 722 PTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP----APTTPKEPAPTT 777

Query: 623 PEFHSSILVTDLGHGTSSPPAPVSRLFPSTAQDPLGKGEQVPLHGGSPQVTVTGPSRDCP 682
           P+  +   + +    T   PAP   L P+T + P       P      +   T P    P
Sbjct: 778 PKGTAPTTLKEPAPTTPKKPAP-KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 836

Query: 683 NS-GQASPCASEQSPSPQSPQNNCSGKSDPKNVAALKNRQMKHISAE 728
            +  + +P   E  P   S  +  +   +P  +    +     +SAE
Sbjct: 837 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 883



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 91/376 (24%), Positives = 121/376 (32%), Gaps = 54/376 (14%)

Query: 348 PASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTED 407
           P +   P P     PA     PTT   T       + P T   LA    +    T+  E 
Sbjct: 594 PTTTKKPAPTTPKEPA-----PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE- 647

Query: 408 PFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPIS-PVLPLVPPPATALNPPAPP 466
             + PT   P EP  + P+            P+P  P  + P  P  P P T    PAP 
Sbjct: 648 --LAPTT--PEEPTPTTPE-----------EPAPTTPKAAAPNTPKEPAPTTP-KEPAPT 691

Query: 467 TFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALS 526
           T  +P        AP+    TA  TL   AP            T   PAP        L+
Sbjct: 692 TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT-----------TPKKPAPK------ELA 734

Query: 527 PVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAAFSGQPQA 586
           P T       T   P P +  G  P  P +  P    EP     K    AP     +  A
Sbjct: 735 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT--APTTL--KEPA 790

Query: 587 VIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSILVTDLGHGTSSPPAPVS 646
                 P  +E  LA T ++     +  +   AP  P+  +     +    T   PAP +
Sbjct: 791 PTTPKKPAPKE--LAPTTTKGPT--STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT 846

Query: 647 RLFPSTAQDPLGKGEQVPLHGGSPQVTVTGPSRDCPN-SGQASPCASEQSP-SPQSPQNN 704
              P T   P       P     P      P    P  S + +P A E SP  P  P   
Sbjct: 847 ---PET-PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTK 902

Query: 705 CSGKSDPKNVAALKNR 720
               + P+     K++
Sbjct: 903 TPAATKPEMTTTAKDK 918



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 92/388 (23%), Positives = 129/388 (33%), Gaps = 47/388 (12%)

Query: 348 PASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTED 407
           PA  +   P P  P       P    PT   P    AP T    A    +    T+  E 
Sbjct: 443 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP----APTTPKEPAPTAPKKPAPTTPKEP 498

Query: 408 PFIQPTDFGPS---EPPLSVPQPFLPVFT--MPLLSPSPAPPPI--SPVLPLVPPPATAL 460
               P +  P+   EP  + P+   P  T   P  +  PAP     +P  P  P P T  
Sbjct: 499 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT- 557

Query: 461 NPPAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAP---- 516
             PAP T  +P        AP+     A  T    AP TT    +    T   PAP    
Sbjct: 558 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT---KKPAPTTPKEPAPTTPK 614

Query: 517 -SAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARI 575
            +A      L+P T       T   P P +     P  P +  P    EP     K    
Sbjct: 615 ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK---- 670

Query: 576 APAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSILVTDLG 635
           A A  + +  A      P       A T  +      P     AP  P+  +   + +  
Sbjct: 671 AAAPNTPKEPAPTTPKEP-------APTTPKEPAPTTPK--ETAPTTPKGTAPTTLKEPA 721

Query: 636 HGTSSPPAPVSRLFPSTAQDPLG----KGEQVPLHGGSP----QVTVTGPSRDCPNSGQA 687
             T   PAP   L P+T ++P      K       G +P    +   T P    P + + 
Sbjct: 722 PTTPKKPAP-KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKG 780

Query: 688 SPCASEQSPSPQSPQNNCSGKSDPKNVA 715
           +   + + P+P +P+     K  PK +A
Sbjct: 781 TAPTTLKEPAPTTPK-----KPAPKELA 803



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 46/216 (21%), Positives = 74/216 (34%), Gaps = 16/216 (7%)

Query: 355  VPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQPTD 414
            VP    P A +  + TTA    +  D    P T  +   M ++    T +T +  I  T 
Sbjct: 898  VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 957

Query: 415  FGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVL---PLVPPPATALNPP-----APP 466
               +        PF  + T+   + +P        +    ++  P     P      +  
Sbjct: 958  TQVTSTTTQDTTPF-KITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 1016

Query: 467  TFHQPQKFAGVNKAPSVITHTAS-ATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLAL 525
            T  +PQK     KAP   T T    T+       T    + +  T     P++      L
Sbjct: 1017 TTPKPQK---PTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAML 1073

Query: 526  SPVTRP---PQPRLTFVHPKPVSLTGGRPKQPHKIV 558
               TRP   P  +L  V+PK     G   + PH ++
Sbjct: 1074 QTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 1109



 Score = 30.8 bits (68), Expect = 6.1
 Identities = 49/239 (20%), Positives = 75/239 (31%), Gaps = 21/239 (8%)

Query: 356  PDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSR-TEDPFIQPTD 414
            P P  P       P T  PT S    +  P T      + +   E T   + +P  +  +
Sbjct: 834  PAPTTPKKPAPTTPETPPPTTS---EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE 890

Query: 415  FGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTFHQPQKF 474
              P EP   VP    P  T P ++ +         L   P   TA       T    +K 
Sbjct: 891  NSPKEP--GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKT 948

Query: 475  AGVNKAPSVITHTASATLTHDAP-----------ATTFSQSQGLVITT---HHPAPSAAP 520
               +K  +  T   S T     P           A   + ++  + TT   + P  +A P
Sbjct: 949  TE-SKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKP 1007

Query: 521  CGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAA 579
               A +     P+P+     PK  + T      P    P   P P  +      + P +
Sbjct: 1008 KDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTS 1066


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 109/427 (25%), Positives = 145/427 (33%), Gaps = 61/427 (14%)

Query: 312 IQPGLIPLQPNLDFMDTFEPFQDLFSSSR--------SIFGSMLPASASAPVPDPNNPPA 363
           + P + PL   L    T  P Q L S +         S+    L   +S   P    PPA
Sbjct: 473 LSPAVSPLSSPL----TIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPA 528

Query: 364 QESILPTTALPTVSLP--DSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQPTDFGPSEPP 421
             +  P   LP+++ P   +  AP T P   H++   C      + P   P    P E P
Sbjct: 529 SLTTPPLENLPSLAPPPLQTASAPLTTP---HLETPPCPAPCPLQAP-PSPLTTPPPETP 584

Query: 422 LSV----PQ-------PFLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTFHQ 470
            S+    PQ       P L     P LSP   PPP +P    +PP     +PPA P    
Sbjct: 585 SSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPL-S 643

Query: 471 PQKFAGVNKAPSVITHTASATLT---HDAPATTFSQSQGLVITTHHPAPSAAPCGLALSP 527
           P          ++  H   A  +          FS      ++     PS AP  LA  P
Sbjct: 644 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP 703

Query: 528 VTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAAFSGQPQAV 587
           +  PP P        P S     P  P    P   P P  L     ++ P+  +  P + 
Sbjct: 704 LQVPPSP--------PAS----PPMSPSATPPPQAPPP--LAAPPLQVPPSPPASPPMSP 749

Query: 588 IMTSGPLKREGMLASTVSQSNVVIAPAAIARAP--GVPEFHSSILVTDLGHGTSSPPAPV 645
             T  P  R   L +          PA++  +P    P      L T       SPPA  
Sbjct: 750 SATPPP--RVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPAS- 806

Query: 646 SRLFPSTAQ-DPLGKGEQVPLHGGSPQV--TVTGPSRDCPNSGQASPC--ASEQSPSPQS 700
              FP  A   P       PL    PQ    +  P    P S  ASP   A  + P+P  
Sbjct: 807 ---FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP-G 862

Query: 701 PQNNCSG 707
           P  + SG
Sbjct: 863 PDTSVSG 869



 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 82/313 (26%), Positives = 120/313 (38%), Gaps = 43/313 (13%)

Query: 348 PASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIA---------PPTAPSLAHMDEQG 398
           P  A  P+  P +PPA   + P  A P+   P++L           PP+ P  A      
Sbjct: 623 PXLALPPLQAPPSPPASPPLSPL-ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 681

Query: 399 CEHTSRTEDPFIQPTDFGPS--EPPLSVPQ--PFLPVFTMPLLSPSPAPPPISPVLPLVP 454
               S +  P   P+   PS   PPL VP   P  P  + P  +P P  PP     PL  
Sbjct: 682 SPPVSPSATP---PSQAPPSLAAPPLQVPPSPPASPPMS-PSATPPPQAPPPLAAPPLQV 737

Query: 455 PPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHP 514
           PP+   +PP  P+   P +   +  AP +        +    PA+       L ++    
Sbjct: 738 PPSPPASPPMSPSATPPPRVPPLLAAPPL-------QVPPSPPAS-------LPMSPLAK 783

Query: 515 APSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPV--SLVLKN 572
            P  AP  LA  P+   P P  +F    P S +   P  P    P P+  PV  + +L+ 
Sbjct: 784 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP-LATPPPQAPPVLAAPLLQV 842

Query: 573 ARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSILVT 632
               PA+ + Q      T GP        ++VS   + +A A     P      S++   
Sbjct: 843 PPSPPASPTLQAPRRPPTPGP-------DTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 895

Query: 633 DL-GHGTSSPPAP 644
           DL GH +S+   P
Sbjct: 896 DLAGHSSSATSTP 908



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 100/384 (26%), Positives = 143/384 (37%), Gaps = 53/384 (13%)

Query: 338 SSRSIFGSMLPASASAPVPDPNNPPAQESILPTTALPTVSLPDSL-------IAPP---T 387
           +SRS+  S  P S+ A      + P+        A P+   P  L       + PP    
Sbjct: 238 ASRSLSSSATPLSSPA-----RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 292

Query: 388 APSLAHMDEQ--GCEHTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFT-MPLLSPSPAPP 444
           AP+L  +          S T+   + P D   +  P ++P P  P+ T +PL  PSP+ P
Sbjct: 293 APALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLP-PSPPLATPLPLAPPSPSAP 351

Query: 445 PISPVLPLVPPPATALNPP--APPTFHQPQKFAGVNK---APSVITHTASATLTHDAPAT 499
           P    LP   PPAT   PP  APP+   P   A  +     P  + H+ ++      P+ 
Sbjct: 352 PSLQTLP--SPPAT---PPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSP 406

Query: 500 TFSQSQGLVITTHHPAPSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVP 559
               S     +   P   A    L +SP  R  Q  LT       +     P Q    +P
Sbjct: 407 LALSSLQATTSLGSPTLQATHSFLTMSP--RQTQASLTSPSRPASTPPDSPPLQAPLSLP 464

Query: 560 APKPEPVSLVLKNARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIARA 619
           A  P   SL       +PA     P +  +T  PL+    LAS   Q     AP +    
Sbjct: 465 ASPPLQTSL-------SPAV---SPLSSPLTIHPLQALSSLASHSPQ-----APLSSLIM 509

Query: 620 PGVPEFHSSILVTDLGHGTSSPPAPVSRLFPSTAQDPLGKGEQVPLHGGSPQVTVTGPSR 679
           P + E  SS+    L    +S   P     PS A  PL +    PL   +P +       
Sbjct: 510 PPL-ETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL-QTASAPL--TTPHLETPPCPA 565

Query: 680 DCPNSGQASPCASEQSPSPQSPQN 703
            CP     SP     +P P++P +
Sbjct: 566 PCPLQAPPSPLT---TPPPETPSS 586



 Score = 33.9 bits (76), Expect = 0.72
 Identities = 68/288 (23%), Positives = 103/288 (35%), Gaps = 33/288 (11%)

Query: 435 PLLSPSPAPPPISPVLPLVPPPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLTH 494
           P  S  P PP   P   +      +   P+P    +P    G+ +  S    +++  L+ 
Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS- 250

Query: 495 DAPATTFSQSQGLVITTHHPAPSAAPCGL-ALSP--VTRP---------PQPRLTFVHPK 542
            +PA +   ++G      HP+    P GL AL P  VT P         P        P 
Sbjct: 251 -SPARSGPSARGTPRAPAHPS-QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308

Query: 543 PVSLTGGRPKQP--HKIVPAPKPEPVSLVLKN-ARIAPAAFSGQPQAVIMTSGPLKREGM 599
           P S T  RP  P  +   P P   P S  L     +AP + S  P    + S P      
Sbjct: 309 P-SGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 367

Query: 600 LASTVSQSNVVIAPAAIARAPGVPEFHSSILVTDLGHGTSSPPAPVSRLFPSTAQDPLGK 659
              +++ +  + AP ++   P +   HS            +PP+P++ L    A   LG 
Sbjct: 368 APPSMT-TPPMQAPPSLQTIPPIQVPHSL-----TSPSLQAPPSPLA-LSSLQATTSLGS 420

Query: 660 GEQVPLHG------GSPQVTVTGPSRDCPNSGQASPCASEQSPSPQSP 701
                 H          Q ++T PSR       + P  +  S  P SP
Sbjct: 421 PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS-LPASP 467



 Score = 33.9 bits (76), Expect = 0.72
 Identities = 28/89 (31%), Positives = 34/89 (38%), Gaps = 22/89 (24%)

Query: 10  PRRPRSRGRQVLLKPQVSEDDDD----------SDTDEPSP--------PPASGAATPAR 51
           P +P+ +G Q L  PQV+    D          S    PSP        PP   AATP  
Sbjct: 269 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLP 328

Query: 52  AHASAAP----PPPRAGPGREEPPRRQQI 76
           A    +P    P P A P    PP  Q +
Sbjct: 329 ATLPPSPPLATPLPLAPPSPSAPPSLQTL 357


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 108/408 (26%), Positives = 136/408 (33%), Gaps = 86/408 (21%)

Query: 347 LPASASAPVPDPNNPPAQESILPTTALPTVSL--------------------PDSLIAPP 386
           LP     P P P  PP     LP+ + P+                         +L  PP
Sbjct: 628 LPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPP 687

Query: 387 TAPSLAHMDEQGCEHTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSP----- 441
           T P +           S++  P I     G   PP   P P  P   M  L P+P     
Sbjct: 688 TPPVM----------QSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSL 737

Query: 442 ----APPP---------ISPVLPLVPPPATALNPPAPPTFHQPQKFAGVNKAPSVITHTA 488
               APPP         I+ V P  PPP   +  P PP    P K      AP+  T T 
Sbjct: 738 PQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPP--QAPPKPLVTIPAPT-STKTV 794

Query: 489 SATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGL--ALSPVTRPPQPRLTFVHPKPVSL 546
           +  +T  AP T              P P   P     A      PP P    V   P +L
Sbjct: 795 APVVTQAAPPT--------------PTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTL 840

Query: 547 TGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQ 606
               PKQ       P P P+S V    +   + F   P    M S PLK   + A+   Q
Sbjct: 841 ----PKQ-QSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLK--PVPANVAPQ 893

Query: 607 SNVVIAPAAIARAPGVPEFHSSILVTDLGHGTSSPPAPVSRLFPSTAQDPLGKGEQVPLH 666
           S     PA  A+    P   SSI V         PP   S +FP     P+      P  
Sbjct: 894 S----PPAVKAKPKWQP---SSIPVP--SPDFPPPPPESSLVFPPPPPSPVPAPPPPPPP 944

Query: 667 GGSPQVTVTGPSRDCPNSGQASPCASEQSPSPQ--SPQNNCSGKSDPK 712
             SP    +G S     S  +SP   +  P+PQ  S   + SG   P+
Sbjct: 945 TASPTPDKSG-SPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPE 991



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 78/321 (24%), Positives = 109/321 (33%), Gaps = 52/321 (16%)

Query: 420 PPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTFHQPQKFAGVNK 479
           PPLS     +  +T    SP   PPP  P  P  PPP     PP PP   Q    AG + 
Sbjct: 607 PPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPP-----PPPPPLPSQSAPSAG-SA 660

Query: 480 AP-----SVITHTASATLTHDA----PATTFSQSQGLVITTHHPAPSAAPCGLALSPVTR 530
           AP     S IT   +A+    A    P     QSQ +      P     P G+   P   
Sbjct: 661 APMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSV-----KPQILVPPNGVVPPPPPP 715

Query: 531 PPQP----RLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIAPAAFSGQPQA 586
           PP P     +  + P P +     P  P    P P P  +  V    ++AP      P  
Sbjct: 716 PPPPTPGSAMAQLKPAPCA-----PSLPQFSAP-PPPLKIHQVQHITQVAPPTPPPPPPI 769

Query: 587 VIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSILVTDLGHGTSSPPAPVS 646
                     + ++      S   +AP     AP  P                +PP P +
Sbjct: 770 PAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTP----------------TPPVPPA 813

Query: 647 RLFPSTAQDPLGKGEQVPLHGGSPQVTVTGPSRDCPNSGQASPCASEQSPSPQSPQNNCS 706
           +      + P      +P    +P V V  P+     S  A P  S  SP P   +   S
Sbjct: 814 K------KQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIAS 867

Query: 707 GKSDPKNVAALKNRQMKHISA 727
               P    A++++ +K + A
Sbjct: 868 QFPPPPTPPAMESQPLKPVPA 888



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 93/375 (24%), Positives = 123/375 (32%), Gaps = 88/375 (23%)

Query: 348  PASASAPVPDPNNPPAQESIL-----PTTALPTV--SLPDSLIAPPTAPSLAHMDEQGCE 400
            P +   PVP P  P  Q         P + +P+V   +      PPT P+   M+ Q  +
Sbjct: 828  PPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPA---MESQPLK 884

Query: 401  HTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPS--PAPPPISPVLPLVPP-PA 457
                       P +  P  PP    +P     ++P+ SP   P PP  S V P  PP P 
Sbjct: 885  PV---------PANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPV 935

Query: 458  TALNPPAPPTFH-QPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAP 516
             A  PP PPT    P K     K  S    T+S       P    + S        HP P
Sbjct: 936  PAPPPPPPPTASPTPDKSGSPGKKTS---KTSSPGGKKPPPTPQRNSSIKSSSGAEHPEP 992

Query: 517  SAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNARIA 576
                    +S  T P +               G P +     PA  P+P           
Sbjct: 993  KRPSVDSLVSKFTPPAE--------------SGSPSKETLPPPAAPPKP----------- 1027

Query: 577  PAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPG---VPEFHSSILVTD 633
                           G L   G+    V Q   V A A +    G   V EF S    +D
Sbjct: 1028 ---------------GKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSD 1072

Query: 634  LGHGTSSPPAPVSRLFPSTAQDPLGKGEQVPLHGG--SPQVTVTGPSRDCPNSGQASPCA 691
                   PP P + L       PL   E   +  G  SP+V V  P        Q S  +
Sbjct: 1073 F-----PPPPPETEL-------PLPPIEIPAVFSGNTSPKVAVVNPQPQ-----QWSKMS 1115

Query: 692  SEQSPSPQSPQNNCS 706
             +++P P  P+ N S
Sbjct: 1116 VKKAPPPTRPKRNDS 1130



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 3/65 (4%)

Query: 38   PSPPPASGAATPARAHASAAPPPPRAGPGREEPPRRQQIIHSGHFMVSSPHREHPPKKGY 97
            P PPP + + TP ++ +        + PG ++PP   Q   S   + SS   EHP  K  
Sbjct: 939  PPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSS---IKSSSGAEHPEPKRP 995

Query: 98   DFDTV 102
              D++
Sbjct: 996  SVDSL 1000


>gi|239508790 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 490

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 96/370 (25%), Positives = 133/370 (35%), Gaps = 45/370 (12%)

Query: 417 PSEPPLSVPQPFLPVFTM-----PLLSP-----SPAPPPISPVLPLVPPPATALNP---- 462
           P  P +S+  P  P F +     PL+SP     SP   P+SP  PLV P  + ++P    
Sbjct: 47  PHHPLVSLHHPVSPHFPLVSPHHPLMSPHYSLVSPQYSPVSPHCPLVSPHYSLVSPHRPL 106

Query: 463 --------PAPPTFHQPQKFAGVNKAPSVITHTAS--ATLTHDAPATTFSQSQGLVITTH 512
                   P+PP+   P   +GV   PS ++   S   +L  D P+              
Sbjct: 107 VSPLLSGVPSPPS-DVPSLLSGVPSLPSDVSSPPSDVPSLLSDVPSLLSGVPSPPSDVPS 165

Query: 513 HPAPSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKN 572
            P+   +P     S ++  P P      P P S     P     +   P P     +L +
Sbjct: 166 PPSDVPSPPSDVPSLLSGVPSPPSDV--PSPPSDVPSPPSDVPLLSDVPSPPSDVPLLSD 223

Query: 573 ARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSIL-- 630
               P+     P  V   SG       + S +  S V   P+ I+    VP   S +   
Sbjct: 224 VPSPPSDVPSLPSDVPSLSGVPSPPSDVPSLL--SGVPSPPSDISPPSDVPSLLSDVPSL 281

Query: 631 ---VTDLGHGTSSPPAPVSRLF---PSTAQDPLGKGEQVPLHGG--SPQVTVTGPSRDCP 682
              V  L  G  SPP+ V  L    PS   D       +PL  G  SP   V  P  D P
Sbjct: 282 PSDVPSLLSGVPSPPSDVPSLLSDVPSPPSDVPSPPSDIPLLSGVPSPPSDVPSPPSDVP 341

Query: 683 NSGQASPCASEQSPSPQSPQNNCSG-KSDPKNVAAL----KNRQMKHISAEQKRRFNIKM 737
           +     P  S   PSP S     SG  S P +V +L        M H S     R ++  
Sbjct: 342 SPPSDVPLLS-GVPSPLSDVPLLSGVPSPPSDVPSLLMSPHRLLMSHYSLVSPHRLDVPS 400

Query: 738 CFDMLNSLIS 747
               + SL+S
Sbjct: 401 LLSDVPSLLS 410



 Score = 53.5 bits (127), Expect = 9e-07
 Identities = 75/301 (24%), Positives = 110/301 (36%), Gaps = 42/301 (13%)

Query: 286 FSTLSSHQPVAWPNPREIAHLGNADMIQPGLIPLQPNLDFMDTFEPFQDLFSSSRSIFGS 345
           F  +S H P+  P+           ++ P   P+ P+   +    P   L S  R +   
Sbjct: 62  FPLVSPHHPLMSPH---------YSLVSPQYSPVSPHCPLVS---PHYSLVSPHRPLVSP 109

Query: 346 MLPASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRT 405
           +L    S P   P+      S+    + P   +P  L   P+   L+ +     +  S  
Sbjct: 110 LLSGVPSPPSDVPSLLSGVPSLPSDVSSPPSDVPSLLSDVPSL--LSGVPSPPSDVPSPP 167

Query: 406 EDPFIQPTDF-----GPSEPPLSVPQPFL----PVFTMPLLSPSPAPPPISPVLPLVPPP 456
            D    P+D      G   PP  VP P      P   +PLLS  P+PP   P+L  VP P
Sbjct: 168 SDVPSPPSDVPSLLSGVPSPPSDVPSPPSDVPSPPSDVPLLSDVPSPPSDVPLLSDVPSP 227

Query: 457 ATAL-----------NPPAPPTFHQPQKFAGVNKAPSVITHTASA-TLTHDAPATTFSQS 504
            + +             P+PP+   P   +GV   PS I+  +   +L  D P+   S  
Sbjct: 228 PSDVPSLPSDVPSLSGVPSPPS-DVPSLLSGVPSPPSDISPPSDVPSLLSDVPSLP-SDV 285

Query: 505 QGLVITTHHPAPSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPE 564
             L+     P PS  P    LS V  PP    +   P  + L  G P  P  +   P   
Sbjct: 286 PSLLSGVPSP-PSDVPS--LLSDVPSPPSDVPS--PPSDIPLLSGVPSPPSDVPSPPSDV 340

Query: 565 P 565
           P
Sbjct: 341 P 341



 Score = 34.3 bits (77), Expect = 0.55
 Identities = 35/119 (29%), Positives = 51/119 (42%), Gaps = 9/119 (7%)

Query: 345 SMLPASASAP--VPDPNNPPAQESILPTTALPTVSLPDSLIAPPT-APSLAHMDEQGCEH 401
           S+L    S P  +  P++ P+  S +P+      SL   + +PP+  PSL  + +     
Sbjct: 253 SLLSGVPSPPSDISPPSDVPSLLSDVPSLPSDVPSLLSGVPSPPSDVPSL--LSDVPSPP 310

Query: 402 TSRTEDPFIQPTDFGPSEPPLSVPQPFL----PVFTMPLLSPSPAPPPISPVLPLVPPP 456
           +     P   P   G   PP  VP P      P   +PLLS  P+P    P+L  VP P
Sbjct: 311 SDVPSPPSDIPLLSGVPSPPSDVPSPPSDVPSPPSDVPLLSGVPSPLSDVPLLSGVPSP 369


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 95/351 (27%), Positives = 126/351 (35%), Gaps = 52/351 (14%)

Query: 338 SSRSIFGSMLPASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQ 397
           S+ +    MLPAS       P    AQ    P+  +    +P SL   P+APS + +  +
Sbjct: 328 SASNALDPMLPASVGGSTRTPRPAAAQ----PSQKITATKIPKSLPTKPSAPSTSIVPIK 383

Query: 398 GCEHTSRTEDPFIQPTDFGPSEPPLS--VPQPFLPVFTMPLLSPSPAPPPI--SPVLPLV 453
               T +T      P+ F  S  P    VP    PV   P     PA  PI  +P +P  
Sbjct: 384 SPHPTQKTA-----PSSFTKSALPTQKQVPPTSRPV---PARVSRPAEKPIQRNPGMPRP 435

Query: 454 PPPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHH 513
           PPP+T    P PPT    +K       P++    A  T     PA+  +       +TH 
Sbjct: 436 PPPSTR---PLPPTTSSSKK-----PIPTLARTEAKITSHASKPASART-------STHK 480

Query: 514 PAPSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSLVLKNA 573
           P P  A   L+ SP   P   R T      V  T G    P      P P       K  
Sbjct: 481 PPPFTA---LSSSPAPTPGSTRSTRPPATMVPPTSG-TSTPRTAPAVPTPGSAPTGSKKP 536

Query: 574 RIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSILVTD 633
             + A+    P++      PL R G  A  V  S++   P+   R P   +  +  LV  
Sbjct: 537 IGSEASKKAGPKSSPRKPVPL-RPGKAARDVPLSDLTTRPS--PRQPQPSQQTTPALVLA 593

Query: 634 LGHGTSSPPAPVS---RLFPSTAQDPLGKGEQVPLHGGSPQVTVTGPSRDC 681
                SS P P S    +F      P       PL  G P     GP  DC
Sbjct: 594 PAQFLSSSPRPTSSGYSIFHLAGSTPF------PLLMGPP-----GPKGDC 633



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 61/271 (22%), Positives = 96/271 (35%), Gaps = 41/271 (15%)

Query: 444 PPISPVLPLVPPPATALNPPAP-----------PTFHQPQKFAGVNKAPSVITHTASATL 492
           P  +P+LP     + AL+P  P           P   QP +     K P  +    SA  
Sbjct: 317 PAQTPLLPAKLSASNALDPMLPASVGGSTRTPRPAAAQPSQKITATKIPKSLPTKPSAPS 376

Query: 493 THDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPK 552
           T   P  +   +Q    ++     SA P    + P +RP   R++    KP+    G P+
Sbjct: 377 TSIVPIKSPHPTQKTAPSSF--TKSALPTQKQVPPTSRPVPARVSRPAEKPIQRNPGMPR 434

Query: 553 QPHKIVPAPKPEPVSLVLKNARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIA 612
            P    P+ +P P +    ++   P     + +A I TS   K      ST         
Sbjct: 435 PP---PPSTRPLPPT---TSSSKKPIPTLARTEAKI-TSHASKPASARTSTHKPPPFTAL 487

Query: 613 PAAIARAPGVPEFHSSILVTDLGHGTSSPPAPVSRLFPSTAQDPLGKGEQVPLHGGSPQV 672
            ++ A  PG                T S   P + + P++          VP  G +P  
Sbjct: 488 SSSPAPTPG---------------STRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAP-- 530

Query: 673 TVTGPSRDCPN--SGQASPCASEQSPSPQSP 701
             TG  +   +  S +A P +S + P P  P
Sbjct: 531 --TGSKKPIGSEASKKAGPKSSPRKPVPLRP 559


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 102/407 (25%), Positives = 145/407 (35%), Gaps = 66/407 (16%)

Query: 345 SMLPASASAPVPD--PNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHT 402
           ++ P   + P  D  P   P   S L T + P+ +L     APPT P+  H     C+  
Sbjct: 279 ALRPPQVTPPRKDAAPALGPLSSSPLATPS-PSAALQSQ--APPTLPATPHSSSLTCQLA 335

Query: 403 --------SRTEDPFIQPTDFGPSEPP-----------LSVPQPFLPVFTM-PLLSPSPA 442
                   S +  P +Q     P+ PP           L     FLP   + PL +P P 
Sbjct: 336 TPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ 395

Query: 443 PPPISPVLPLVPPPATALNPP-APPTFHQPQKFAGVNKAPSVI-THTASATLT---HDAP 497
            PP   + PL  PP+   +PP +P     PQ       AP+ +  H   A  +       
Sbjct: 396 APPALALPPLQAPPSPPASPPLSPLATPSPQ-------APNALAVHLLQAPFSPPPSPPV 448

Query: 498 ATTFSQSQGLVITTHHPAPSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQ---- 553
              FS      ++     PS AP  LA  P+  PP P  +     P+S +   P Q    
Sbjct: 449 QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS----PPMSPSATPPPQAPPP 504

Query: 554 ----PHKIVPAPKPEPVSLV---LKNARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQ 606
               P ++   P   P +L    L+     PA+F GQ       S P+     LA+   Q
Sbjct: 505 LAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM---SPLATPPPQ 561

Query: 607 SNVVIAPAAIARAPGVPEFHSSILVTDLGHGTSSPPAPVS--RLFPSTAQDPLGKGEQVP 664
           +  V+A   +   P  P   S  L       T  P   VS  RL  + A  P       P
Sbjct: 562 APPVLAAPLLQVPPSPPA--SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP------PP 613

Query: 665 LHGGSPQVTVTGPSRDCPNSGQASPCASEQSPSPQSPQNNCSGKSDP 711
               SP  T++GP     +S  A+    E       P+   +    P
Sbjct: 614 PPSRSPSSTLSGPDL-AGHSSSATSTPEELRGYDSGPEGGAAASPPP 659



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 63/269 (23%), Positives = 91/269 (33%), Gaps = 34/269 (12%)

Query: 435 PLLSPSPAPPPISPVLPLVPPPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLTH 494
           P  S  P PP   P   +      +   P+P    +P    G+ +  S    +++  L+ 
Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS- 250

Query: 495 DAPATTFSQSQGLVITTHHPAPSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQP 554
            +PA +   ++G      HP+    P GL      RPPQ         P          P
Sbjct: 251 -SPARSGPSARGTPRAPAHPS-QPKPKGL---QALRPPQ-------VTPPRKDAAPALGP 298

Query: 555 HKIVPAPKPEPVSLVLKNARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPA 614
               P   P P + +      AP      P +  +T        +   + S      AP 
Sbjct: 299 LSSSPLATPSPSAALQSQ---APPTLPATPHSSSLTCQLATPLPLAPPSPS------APP 349

Query: 615 AIARAPGVPEFHSSILVTDLGHGTSSPPAPVSRLF-PSTAQDPLGKGEQVPLHGGSPQVT 673
           ++   P  P    S   T LG    SP    +  F PS    PL      P     P + 
Sbjct: 350 SLQTLPSPPATPPSQATTSLG----SPTLQATHSFLPSPPLSPLA----TPPPQAPPALA 401

Query: 674 VTGPSRDCPNSGQASPCASE-QSPSPQSP 701
           +  P    P S  ASP  S   +PSPQ+P
Sbjct: 402 L--PPLQAPPSPPASPPLSPLATPSPQAP 428


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 64/216 (29%), Positives = 79/216 (36%), Gaps = 25/216 (11%)

Query: 358 PNNPPAQESILPTT--ALPTVSLPDSLIAP--PTAPSLAHMDEQGCEHTSRTEDPFIQPT 413
           P  PP  ES+ P     LP   +P +  AP  P  P        G    +    P + P 
Sbjct: 242 PPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPA----PVVHPP 297

Query: 414 DFG--PSEPPLSVPQPFL----PVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPT 467
             G  P  P +  P P +    P    P     P  P + P  P V PPA  ++PPAP  
Sbjct: 298 ASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGV 357

Query: 468 FHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSP 527
            H P    GV+  PS   H   A   H A      Q+ G+    H PAP   P    + P
Sbjct: 358 -HPPAP--GVHPPPSAGVHP-QAPGVHPAAPAVHPQAPGV----HPPAPGMHPQAPGVHP 409

Query: 528 VTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKP 563
                 P    VHP+P    G  P  P    P P P
Sbjct: 410 QPPGVHPSAPGVHPQP---PGVHPSNPGVHPPTPMP 442



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 60/189 (31%), Positives = 76/189 (40%), Gaps = 25/189 (13%)

Query: 385 PPTAPSLAHMDEQGCEHTSRTEDPFIQPTDFGPSEPPL--SVPQP---FLPVFTMPLLSP 439
           PP  PSL      G     R   P +      P  PPL  S+P P    LP+  MP   P
Sbjct: 217 PPAPPSLP----AGPPGVKRPPPPLMNGL---PPRPPLPESLPPPPPGGLPLPPMPPTGP 269

Query: 440 SPAPPPISPVLPLVPPPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPAT 499
           +P+ PP  P LP   PPA  ++PPA P  H P   +GV+  P+   H  +  +   AP  
Sbjct: 270 APSGPPGPPQLP---PPAPGVHPPA-PVVHPPA--SGVH-PPAPGVHPPAPGVHPPAPGV 322

Query: 500 --TFSQSQGLVITTHHPAPSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQP--H 555
               S         H PAP   P    + P      P    VHP P +  G  P+ P  H
Sbjct: 323 HPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSA--GVHPQAPGVH 380

Query: 556 KIVPAPKPE 564
              PA  P+
Sbjct: 381 PAAPAVHPQ 389



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 54/190 (28%), Positives = 68/190 (35%), Gaps = 39/190 (20%)

Query: 348 PASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTS---R 404
           PAS   P     +PPA     P    P V  P S + PP AP + H    G    +    
Sbjct: 297 PASGVHPPAPGVHPPAPGVHPPA---PGVHPPTSGVHPP-APGV-HPPAPGVHPPAPGVH 351

Query: 405 TEDPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPA 464
              P + P   G   PP +   P  P          PA P + P  P V PPA  ++P A
Sbjct: 352 PPAPGVHPPAPGVHPPPSAGVHPQAP-------GVHPAAPAVHPQAPGVHPPAPGMHPQA 404

Query: 465 PPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLA 524
           P    QP    GV+          SA   H  P      + G+    H P P        
Sbjct: 405 PGVHPQP---PGVH---------PSAPGVHPQPPGVHPSNPGV----HPPTP-------- 440

Query: 525 LSPVTRPPQP 534
           + P+ RPP P
Sbjct: 441 MPPMLRPPLP 450



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 34/120 (28%), Positives = 44/120 (36%), Gaps = 9/120 (7%)

Query: 348 PASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTED 407
           PA    P     +PP    + P    P V  P +    P AP + H    G    +    
Sbjct: 353 PAPGVHPPAPGVHPPPSAGVHPQA--PGVH-PAAPAVHPQAPGV-HPPAPGMHPQAPGVH 408

Query: 408 PFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPT 467
           P  QP    PS P +    P +      +  P+P PP + P LP   P      PP PPT
Sbjct: 409 P--QPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNI---PPPPPT 463



 Score = 30.8 bits (68), Expect = 6.1
 Identities = 47/177 (26%), Positives = 58/177 (32%), Gaps = 35/177 (19%)

Query: 441 PAPPPISPVLPLV---PPPATALNPPAPPTFHQ--PQKFAGVNKAPSVITHTA------- 488
           PAPP +    P V   PPP     PP PP      P    G+   P   T  A       
Sbjct: 218 PAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGP 277

Query: 489 ------------SATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALSPVTRPPQPRL 536
                        A + H   +     + G+    H PAP   P    + P T    P  
Sbjct: 278 PQLPPPAPGVHPPAPVVHPPASGVHPPAPGV----HPPAPGVHPPAPGVHPPTSGVHPPA 333

Query: 537 TFVHPKPVSL----TGGRPKQP--HKIVPAPKPEPVSLVLKNA-RIAPAAFSGQPQA 586
             VHP    +     G  P  P  H   P   P P + V   A  + PAA +  PQA
Sbjct: 334 PGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQA 390


>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
           [Homo sapiens]
          Length = 1132

 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 86/361 (23%), Positives = 121/361 (33%), Gaps = 68/361 (18%)

Query: 353 APVPDPNNPPAQESILPTT-ALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQ 411
           +P+P P   P     +P    +P   +P     PP   +L        +  + T    I 
Sbjct: 641 SPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGAL--------QPPAFTPPLGIP 692

Query: 412 PTDFGPSEPPLSVPQPFL-----PVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPP 466
           P  FGP  PP   P PFL     P+   P   P   PPPI+P +  +PPP T      PP
Sbjct: 693 PPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVS-IPPPHT------PP 745

Query: 467 TFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALS 526
                   AG+N+  +      +   T  + A   ++S   V       P AAP  L   
Sbjct: 746 ISIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTP 805

Query: 527 PVTRP----------PQPRLTFVHPKPVSLTGGRP-----KQPHKIVP---------APK 562
           PVT+P          P P +    P    L G RP     ++P  + P          P+
Sbjct: 806 PVTQPVSLLGTQGVAPGPVIGLQAPS-TGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPR 864

Query: 563 PEPVSLVLKNARIAPAAFSGQP----QAVIMTSGPLKREGMLASTVSQSNVVIAPAAIAR 618
           P P  ++ +     P  F+  P    +      GP  R G +                  
Sbjct: 865 PMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGL----------GGPGP 914

Query: 619 APGVPEFHSSILVTDLGHGTSSPPAPVSRLFPSTAQDPLGKGEQVPLHGGSPQVTVTGPS 678
            PG PE        D       P  P  +  P   Q P  + +Q P     P  T   P 
Sbjct: 915 GPGGPE--------DRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQ 966

Query: 679 R 679
           +
Sbjct: 967 Q 967



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 47/206 (22%), Positives = 68/206 (33%), Gaps = 32/206 (15%)

Query: 265 PMEEDPLLDTDMLMSEFSDTL----FSTLSSHQPVAWPNPREIAHLGNADMIQPGLIPLQ 320
           P  + P LD  ++    + T       T  S Q  A+P P +                L 
Sbjct: 197 PKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKK---------LL 247

Query: 321 PNLDFMDTFEPFQDLFSSSRSIFGSMLPASASAPVPDPNNPPAQESILPTTALPTVSLPD 380
              D+ D  E  ++      +   +  PA+A         PPA  + +P  A P  + P 
Sbjct: 248 DRFDYDDEPEAVEESKKEDTTAVTTTAPAAAV--------PPAPTATVPAAAAPAAASPP 299

Query: 381 SLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPS 440
              AP   P          +H +  +    QP   G  + P+    P  P   MP     
Sbjct: 300 PPQAPFGFPGDGMQQPAYTQHQNMDQ---FQPRMMGIQQDPMHHQVPLPPNGQMPGFGLL 356

Query: 441 PAPPPISPVLPLVPPPATALNPPAPP 466
           P PP         PP A  + PP PP
Sbjct: 357 PTPP--------FPPMAQPVIPPTPP 374



 Score = 35.4 bits (80), Expect = 0.25
 Identities = 77/320 (24%), Positives = 102/320 (31%), Gaps = 63/320 (19%)

Query: 430 PVFTMPLLSPSPAPPPISPVLPLVPPPAT-----------ALNPPA--PPTFHQPQKFA- 475
           PV  +P   P P PP   P    VPPP             AL PPA  PP    P  F  
Sbjct: 639 PVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGP 698

Query: 476 GVNKAPSVITHTASATLTHDAPATTFSQSQGLVIT--THHPAPSAAPCGL---ALSPVTR 530
           GV   P               P           IT     P P   P  +    ++ +  
Sbjct: 699 GVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNSTIAGINE 758

Query: 531 PPQPRLTFVHPKPVSLTGGR-----------------PKQPHKIVPAPKPEPVSLVLKNA 573
                L+  +P P  ++G R                 P  P  +   P  +PVSL L   
Sbjct: 759 DTTKDLSIGNPIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSL-LGTQ 817

Query: 574 RIAPAAFSG--QPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSILV 631
            +AP    G   P   ++ + P    G++     Q    + P  + R P +P       +
Sbjct: 818 GVAPGPVIGLQAPSTGLLGARP----GLIP---LQRPPGMPPPHLQRFPLMPPRPMPPHM 870

Query: 632 TDLGHGTSSPPAPVSRLFPSTAQDPLGKGEQVPLH------GGSPQVTVTGPSRDCP--- 682
              G     PP P     P     P G     P H      GG P +   GP    P   
Sbjct: 871 MHRG----PPPGPGGFAMP----PPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDR 922

Query: 683 NSGQASPCASEQSPSPQSPQ 702
           +  Q  P   +Q P PQ+PQ
Sbjct: 923 DGRQQPPQQPQQQPQPQAPQ 942



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 34/159 (21%), Positives = 54/159 (33%), Gaps = 7/159 (4%)

Query: 314 PGLIPLQPNLDFMDTFEPFQDLFSSSRSIFGSMLPASASAPVPDPNNPPAQESILPTTAL 373
           P  +P  P L   D F     LF +++      +  +   P P P +P    +++     
Sbjct: 156 PNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQP-PKPQSPALDNAVMAQVQA 214

Query: 374 PTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFT 433
            T  L  +    PT PS         E  +  +   +   D+   EP             
Sbjct: 215 ITAQLKTT----PTQPSEQKAAFPPPEQKTAFDKKLLDRFDYD-DEPEAVEESKKEDTTA 269

Query: 434 MPLLSPSPAPPPI-SPVLPLVPPPATALNPPAPPTFHQP 471
           +   +P+ A PP  +  +P    PA A  PP    F  P
Sbjct: 270 VTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFP 308



 Score = 31.6 bits (70), Expect = 3.6
 Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 13/65 (20%)

Query: 23  KPQVSEDDDDSDTDEPSP-------PPASGAATPARAH-ASAAPPPPRA-----GPGREE 69
           +P+  E+    DT   +        PPA  A  PA A  A+A+PPPP+A     G G ++
Sbjct: 255 EPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQ 314

Query: 70  PPRRQ 74
           P   Q
Sbjct: 315 PAYTQ 319


>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1
           [Homo sapiens]
          Length = 1147

 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 86/361 (23%), Positives = 121/361 (33%), Gaps = 68/361 (18%)

Query: 353 APVPDPNNPPAQESILPTT-ALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQ 411
           +P+P P   P     +P    +P   +P     PP   +L        +  + T    I 
Sbjct: 656 SPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGAL--------QPPAFTPPLGIP 707

Query: 412 PTDFGPSEPPLSVPQPFL-----PVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPP 466
           P  FGP  PP   P PFL     P+   P   P   PPPI+P +  +PPP T      PP
Sbjct: 708 PPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVS-IPPPHT------PP 760

Query: 467 TFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALS 526
                   AG+N+  +      +   T  + A   ++S   V       P AAP  L   
Sbjct: 761 ISIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTP 820

Query: 527 PVTRP----------PQPRLTFVHPKPVSLTGGRP-----KQPHKIVP---------APK 562
           PVT+P          P P +    P    L G RP     ++P  + P          P+
Sbjct: 821 PVTQPVSLLGTQGVAPGPVIGLQAPS-TGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPR 879

Query: 563 PEPVSLVLKNARIAPAAFSGQP----QAVIMTSGPLKREGMLASTVSQSNVVIAPAAIAR 618
           P P  ++ +     P  F+  P    +      GP  R G +                  
Sbjct: 880 PMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGL----------GGPGP 929

Query: 619 APGVPEFHSSILVTDLGHGTSSPPAPVSRLFPSTAQDPLGKGEQVPLHGGSPQVTVTGPS 678
            PG PE        D       P  P  +  P   Q P  + +Q P     P  T   P 
Sbjct: 930 GPGGPE--------DRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQ 981

Query: 679 R 679
           +
Sbjct: 982 Q 982



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 47/206 (22%), Positives = 68/206 (33%), Gaps = 32/206 (15%)

Query: 265 PMEEDPLLDTDMLMSEFSDTL----FSTLSSHQPVAWPNPREIAHLGNADMIQPGLIPLQ 320
           P  + P LD  ++    + T       T  S Q  A+P P +                L 
Sbjct: 212 PKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKK---------LL 262

Query: 321 PNLDFMDTFEPFQDLFSSSRSIFGSMLPASASAPVPDPNNPPAQESILPTTALPTVSLPD 380
              D+ D  E  ++      +   +  PA+A         PPA  + +P  A P  + P 
Sbjct: 263 DRFDYDDEPEAVEESKKEDTTAVTTTAPAAAV--------PPAPTATVPAAAAPAAASPP 314

Query: 381 SLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPS 440
              AP   P          +H +  +    QP   G  + P+    P  P   MP     
Sbjct: 315 PPQAPFGFPGDGMQQPAYTQHQNMDQ---FQPRMMGIQQDPMHHQVPLPPNGQMPGFGLL 371

Query: 441 PAPPPISPVLPLVPPPATALNPPAPP 466
           P PP         PP A  + PP PP
Sbjct: 372 PTPP--------FPPMAQPVIPPTPP 389



 Score = 35.4 bits (80), Expect = 0.25
 Identities = 77/320 (24%), Positives = 102/320 (31%), Gaps = 63/320 (19%)

Query: 430 PVFTMPLLSPSPAPPPISPVLPLVPPPAT-----------ALNPPA--PPTFHQPQKFA- 475
           PV  +P   P P PP   P    VPPP             AL PPA  PP    P  F  
Sbjct: 654 PVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGP 713

Query: 476 GVNKAPSVITHTASATLTHDAPATTFSQSQGLVIT--THHPAPSAAPCGL---ALSPVTR 530
           GV   P               P           IT     P P   P  +    ++ +  
Sbjct: 714 GVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNSTIAGINE 773

Query: 531 PPQPRLTFVHPKPVSLTGGR-----------------PKQPHKIVPAPKPEPVSLVLKNA 573
                L+  +P P  ++G R                 P  P  +   P  +PVSL L   
Sbjct: 774 DTTKDLSIGNPIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSL-LGTQ 832

Query: 574 RIAPAAFSG--QPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVPEFHSSILV 631
            +AP    G   P   ++ + P    G++     Q    + P  + R P +P       +
Sbjct: 833 GVAPGPVIGLQAPSTGLLGARP----GLIP---LQRPPGMPPPHLQRFPLMPPRPMPPHM 885

Query: 632 TDLGHGTSSPPAPVSRLFPSTAQDPLGKGEQVPLH------GGSPQVTVTGPSRDCP--- 682
              G     PP P     P     P G     P H      GG P +   GP    P   
Sbjct: 886 MHRG----PPPGPGGFAMP----PPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDR 937

Query: 683 NSGQASPCASEQSPSPQSPQ 702
           +  Q  P   +Q P PQ+PQ
Sbjct: 938 DGRQQPPQQPQQQPQPQAPQ 957



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 34/159 (21%), Positives = 54/159 (33%), Gaps = 7/159 (4%)

Query: 314 PGLIPLQPNLDFMDTFEPFQDLFSSSRSIFGSMLPASASAPVPDPNNPPAQESILPTTAL 373
           P  +P  P L   D F     LF +++      +  +   P P P +P    +++     
Sbjct: 171 PNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQP-PKPQSPALDNAVMAQVQA 229

Query: 374 PTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFT 433
            T  L  +    PT PS         E  +  +   +   D+   EP             
Sbjct: 230 ITAQLKTT----PTQPSEQKAAFPPPEQKTAFDKKLLDRFDYD-DEPEAVEESKKEDTTA 284

Query: 434 MPLLSPSPAPPPI-SPVLPLVPPPATALNPPAPPTFHQP 471
           +   +P+ A PP  +  +P    PA A  PP    F  P
Sbjct: 285 VTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFP 323



 Score = 31.6 bits (70), Expect = 3.6
 Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 13/65 (20%)

Query: 23  KPQVSEDDDDSDTDEPSP-------PPASGAATPARAH-ASAAPPPPRA-----GPGREE 69
           +P+  E+    DT   +        PPA  A  PA A  A+A+PPPP+A     G G ++
Sbjct: 270 EPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQ 329

Query: 70  PPRRQ 74
           P   Q
Sbjct: 330 PAYTQ 334


>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
          Length = 1526

 Score = 60.5 bits (145), Expect = 7e-09
 Identities = 103/414 (24%), Positives = 157/414 (37%), Gaps = 82/414 (19%)

Query: 348  PASAS----APVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTS 403
            P+S+S    +P   P   P Q   +    +P  SLP   I P  APS           T 
Sbjct: 1027 PSSSSGLGTSPSSSPRTSPCQSPTISEGPVP--SLP---IRPSRAPS----------RTP 1071

Query: 404  RTEDPFIQPTDFGPSEP-PLSVP-QPFLPVFTMPLLSPSPAPPPISPVLPLVPPPATALN 461
                    P D  P+ P P   P QP  P    P   P P  PP  P  P  PPP +  +
Sbjct: 1072 GPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPP---PRPVAPPTRPAPPQRPPPPSGRS 1128

Query: 462  PPAP--------PTFHQPQK-----FAGVNKAPSVITHTASATLTHDAPATTFSQSQGLV 508
             P+P        P  +   +      AGV  AP      ++  LT ++ + T   S+G  
Sbjct: 1129 QPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGST 1188

Query: 509  ITTHHPAPSAA--PCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPV 566
                   P AA  P      P  R  +P +    P P S       QP+   P P+P P 
Sbjct: 1189 FLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQS-----GPQPNLETP-PQPPPR 1242

Query: 567  SLVLKNARIAPAAFSGQPQAVIMTSG--------PLKRE-------GMLASTVSQSNVVI 611
            S   +++   P+  S QPQ  + T+G        PLK +        +LA + +Q +V  
Sbjct: 1243 S---RSSHSLPSEASSQPQ--VKTNGISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQT 1297

Query: 612  APAAI---ARAPGVPEFHSSILVTDLGHGTSSPPAPVSRLFPSTAQDPLGKGEQVPLHGG 668
            +P       R   +P    S +++ +    + PP P      S +Q+ +           
Sbjct: 1298 SPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPAR----SQSQENM---------RS 1344

Query: 669  SPQVTVTGPSRDCPNSGQ-ASPCASEQSPSPQSPQNNCSGKSDPKNVAALKNRQ 721
            SP   +TG +R  P S + A+P    ++ S +S   +   K +P  ++   + Q
Sbjct: 1345 SPNPFITGLTRTNPFSDRTAAPGNPFRAKSEESEATSWFSKEEPVTISPFPSLQ 1398



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 22/90 (24%), Positives = 35/90 (38%), Gaps = 5/90 (5%)

Query: 9    SPRRPRSRGRQVLLKPQ--VSEDDDDSDTDEPSPPPASGAATPARAHASAAPPPPRAGPG 66
            +P  P ++   +  +P   + + D     +   PPP    A P R      PPPP    G
Sbjct: 1070 TPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPP---SG 1126

Query: 67   REEPPRRQQIIHSGHFMVSSPHREHPPKKG 96
            R +P  +  +   G    S+     PP+ G
Sbjct: 1127 RSQPSPQAGLAGPGPAGYSTARPTIPPRAG 1156


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 112/450 (24%), Positives = 156/450 (34%), Gaps = 85/450 (18%)

Query: 282 SDTLFSTLSSHQPVAWPNPREIAHLGNADMIQPGLIPLQPNLDFMDTFEPFQDLFSSSRS 341
           S T  S+ +   P A   PR  AH            P QP    +    P Q   +  R 
Sbjct: 236 SATPLSSPARSGPSARGTPRAPAH------------PSQPKPKGLQALRPPQ--VTPPRK 281

Query: 342 IFGSMLPASASAPV--PDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGC 399
                L   +S+P+  P P+ PP+  +      LP+         P T PS A       
Sbjct: 282 DAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPS--------PPATPPSQA------- 326

Query: 400 EHTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVPPPATA 459
             T+    P +Q T      PPLS           PL +P P  PP   + PL  PP+  
Sbjct: 327 --TTSLGSPTLQATHSFLPSPPLS-----------PLATPPPQAPPALALPPLQAPPSPP 373

Query: 460 LNPP-APPTFHQPQKFAGVNKAPSVI-THTASATLT---HDAPATTFSQSQGLVITTHHP 514
            +PP +P     PQ       AP+ +  H   A  +          FS      ++    
Sbjct: 374 ASPPLSPLATPSPQ-------APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 426

Query: 515 APSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQ--------PHKIVPAPKPEPV 566
            PS AP  LA  P+  PP P  +     P+S +   P Q        P ++   P   P 
Sbjct: 427 PPSQAPPSLAAPPLQVPPSPPAS----PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 482

Query: 567 SLV---LKNARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAIARAPGVP 623
           +L    L+     PA+F GQ       S P+     LA+   Q+  V+A   +   P  P
Sbjct: 483 ALATPPLQALPSPPASFPGQAPFSPSASLPM---SPLATPPPQAPPVLAAPLLQVPPSPP 539

Query: 624 EFHSSILVTDLGHGTSSPPAPVS--RLFPSTAQDPLGKGEQVPLHGGSPQVTVTGPSRDC 681
              S  L       T  P   VS  RL  + A  P       P    SP  T++GP    
Sbjct: 540 A--SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP------PPPPSRSPSSTLSGPDL-A 590

Query: 682 PNSGQASPCASEQSPSPQSPQNNCSGKSDP 711
            +S  A+    E       P+   +    P
Sbjct: 591 GHSSSATSTPEELRGYDSGPEGGAAASPPP 620



 Score = 35.0 bits (79), Expect = 0.32
 Identities = 62/289 (21%), Positives = 105/289 (36%), Gaps = 30/289 (10%)

Query: 435 PLLSPSPAPPPISPVLPLVPPPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLTH 494
           P  S  P PP   P   +      +   P+P    +P    G+ +  S    +++  L+ 
Sbjct: 183 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS- 241

Query: 495 DAPATTFSQSQGLVITTHHPAPSAAPCGLALSPVTRPPQ---------PRLTFVHPKPVS 545
            +PA +   ++G      HP+    P GL      RPPQ         P L  +   P++
Sbjct: 242 -SPARSGPSARGTPRAPAHPS-QPKPKGL---QALRPPQVTPPRKDAAPALGPLSSSPLA 296

Query: 546 L-TGGRPKQPH-----KIVPAPKPEPVSLVLKN----ARIAPAAFSGQPQAVIMTSGPLK 595
             +   P  P      + +P+P   P S    +       A  +F   P    + + P +
Sbjct: 297 TPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ 356

Query: 596 REGMLASTVSQS--NVVIAPAAIARAPGVPEFHSSILVTDLGHGTSSPPA-PVSRLFPST 652
               LA    Q+  +   +P     A   P+  +++ V  L    S PP+ PV   F   
Sbjct: 357 APPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 416

Query: 653 AQDPLGKGEQVPLHGGSPQVTVTGPSRDCPNSGQASPCASEQSPSPQSP 701
           A  P+      P    +P      P +  P+   + P +   +P PQ+P
Sbjct: 417 ASPPVSPSATPP--SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 463



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 20/86 (23%), Positives = 33/86 (38%), Gaps = 8/86 (9%)

Query: 10  PRRPRSRGRQVLLKPQVSEDDDD--------SDTDEPSPPPASGAATPARAHASAAPPPP 61
           P +P+ +G Q L  PQV+    D        S +   +P P++  +  A       P PP
Sbjct: 260 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPP 319

Query: 62  RAGPGREEPPRRQQIIHSGHFMVSSP 87
              P +         + + H  + SP
Sbjct: 320 ATPPSQATTSLGSPTLQATHSFLPSP 345


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 51/172 (29%), Positives = 71/172 (41%), Gaps = 25/172 (14%)

Query: 346 MLPASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRT 405
           ++P S    VP P  PP+  S  P   LP  SL  S   PP  P  +          S T
Sbjct: 564 VMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSL-SSAGPPPVLPPPS---------LSST 613

Query: 406 EDPFIQPTD-FGPSEPPLSVPQPFLPVFTMPLLSPSPAPP---------PISPVLPLVPP 455
             P + P      + PP  +P P +P    P L+ +P PP         P  P   L+P 
Sbjct: 614 APPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPT 673

Query: 456 PATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGL 507
           P +  + P P T+H P + AG    PS   ++ +       P ++FS  QGL
Sbjct: 674 PVSFGSAP-PTTYHPPLQSAG----PSEQVNSKAPLSKSALPYSSFSSDQGL 720



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 69/257 (26%), Positives = 97/257 (37%), Gaps = 42/257 (16%)

Query: 322 NLDFMDTFEPFQDLFSSSRSIFGSMLPASASAPVPDPNNPPAQESILPTTALP----TVS 377
           N+     F P+  +     ++   +LP S    +P P  PPA  + +P   +P      S
Sbjct: 513 NMSMPPPFVPYSQMPPPLPTMPPPVLPPS----LPPPVMPPALPATVPPPGMPPPVMPPS 568

Query: 378 LPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFTMPLL 437
           LP S+  P   PSL          +S    P + P     + PP  +P P L        
Sbjct: 569 LPTSVPPPGMPPSL----------SSAGPPPVLPPPSLSSAGPPPVLPPPSL-------- 610

Query: 438 SPSPAPPPISPVLPL---VPPPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLTH 494
             S APPP+ P+ PL    PPP   + PP  P    PQ  A     P   +  +S     
Sbjct: 611 -SSTAPPPVMPLPPLSSATPPP--GIPPPGVPQGIPPQLTAA--PVPPASSSQSSQVPEK 665

Query: 495 DAPA---TTFSQSQGLVITTHHPAPSAAPCGLALS--PVTRPPQPRLTFVHPKPVSLTGG 549
             PA   T  S       T H P  SA P     S  P+++   P  +F   + +  +  
Sbjct: 666 PRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSA 725

Query: 550 RPKQPHKIVPAPKPEPV 566
            P QP   + A K  PV
Sbjct: 726 APSQP---ITAVKDMPV 739



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 56/204 (27%), Positives = 76/204 (37%), Gaps = 22/204 (10%)

Query: 422 LSVPQPFLPVFTMPLLSPSPAPPPISPVL--PLVPP--PATALNPPAPPTFHQPQKFAGV 477
           +S+P PF+P   MP   P+  PP + P L  P++PP  PAT   P  PP    P     V
Sbjct: 514 MSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSV 573

Query: 478 NKAPSVITHTASATLTHDAPATTFSQS--------QGLVITTHHPAPSAAPCGLALSPVT 529
              P +    +SA      P  + S +          L  T   P     P   A  P  
Sbjct: 574 -PPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPG 632

Query: 530 RPP-------QPRLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSL-VLKNARIAPAAFS 581
            PP        P+LT   P P + +    + P K  PA  P PVS          P   S
Sbjct: 633 IPPPGVPQGIPPQLT-AAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQS 691

Query: 582 GQPQAVIMTSGPLKREGMLASTVS 605
             P   + +  PL +  +  S+ S
Sbjct: 692 AGPSEQVNSKAPLSKSALPYSSFS 715



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 55/231 (23%), Positives = 89/231 (38%), Gaps = 40/231 (17%)

Query: 355 VPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQPTD 414
           +P P  PP    ++P         P   + PP  P+L++  +Q  +H         Q   
Sbjct: 81  LPPPPLPPPP--VMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKH---------QMLH 129

Query: 415 FGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPPTFHQPQKF 474
                PP  VP        M L SP P  PP+ P    +PP  + + PP PP  + P   
Sbjct: 130 HQRDGPPGLVP--------MELESP-PESPPVPPG-SYMPPSQSYMPPPQPPPSYYPPTS 179

Query: 475 AGVNKAP------------SVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCG 522
           +     P            S +  T S + +  +  +  S SQ   + +   +PS    G
Sbjct: 180 SQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQS-YLPSSQASPSRPSQG 238

Query: 523 LALSPVTRPPQP-----RLTFVHPKPVSLTGGRPKQPHKIVPAPKPEPVSL 568
            + S +  PP P       T V  +P+  +G + K   +   AP+P+P ++
Sbjct: 239 HSKSQLLAPPPPSAPPGNKTTVQQEPLE-SGAKNKSTEQQQAAPEPDPSTM 288



 Score = 35.4 bits (80), Expect = 0.25
 Identities = 42/186 (22%), Positives = 68/186 (36%), Gaps = 27/186 (14%)

Query: 396  EQGCEHTSRTEDPFIQPTDFGP----SEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLP 451
            E   ++TS     +  P  + P     +PP S+ +P  P    P  S  P   P  P+ P
Sbjct: 1493 ESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAP----PARSSVPVTRPPVPIPP 1548

Query: 452  LVPPPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITT 511
              PPP     PP PP   +PQ  A   +     +         +    +  +S+   I +
Sbjct: 1549 PPPPPPL---PPPPPVI-KPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPS 1604

Query: 512  ---------HHPAPSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQPHKIVPAPK 562
                     H   P   P  + + P+++PP  + T      V    GR    +K+   P 
Sbjct: 1605 APVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQT------VDYGHGRDISTNKVEQIPY 1658

Query: 563  PEPVSL 568
             E ++L
Sbjct: 1659 GERITL 1664



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 48/204 (23%), Positives = 73/204 (35%), Gaps = 32/204 (15%)

Query: 313 QPGLIPLQPNLDFMDTFEPFQDLFSSSRSIFG---SMLPASASAPV-------------- 355
           QP      P+  ++     +    SSS+S      S LP+S ++P               
Sbjct: 188 QPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAP 247

Query: 356 PDPNNPPAQESILPTTALPT----VSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPFIQ 411
           P P+ PP  ++ +    L +     S      AP   PS     EQ      +      Q
Sbjct: 248 PPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQ 307

Query: 412 PTDF---GPSEPPL---SVPQPFLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAP 465
            T     G  + P+     P+P     T+P  S  P  P  S   P +PPP   + PP P
Sbjct: 308 RTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESP--SSEEPPLPPPNEEVPPPLP 365

Query: 466 PTFHQ---PQKFAGVNKAPSVITH 486
           P   Q   P++ A + +  +   H
Sbjct: 366 PEEPQSEDPEEDARLKQLQAAAAH 389



 Score = 32.3 bits (72), Expect = 2.1
 Identities = 36/134 (26%), Positives = 54/134 (40%), Gaps = 25/134 (18%)

Query: 348 PASASAPVPDPNNPPAQESILPT-----TALPTVSLPDSLIAPPTAP--SLAHMDEQGCE 400
           PAS+S     P  P  + ++LPT     +A PT   P    A P+    S A + +    
Sbjct: 653 PASSSQSSQVPEKP--RPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALP 710

Query: 401 HTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVPPPATAL 460
           ++S + D  +  +   PS       QP   V  MP+ S    P P         P ++ L
Sbjct: 711 YSSFSSDQGLGESSAAPS-------QPITAVKDMPVRSGGLLPDP---------PRSSYL 754

Query: 461 NPPAPPTFHQPQKF 474
             P  P F  P++F
Sbjct: 755 ESPRGPRFDGPRRF 768


>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
          Length = 1711

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 87/314 (27%), Positives = 122/314 (38%), Gaps = 46/314 (14%)

Query: 289 LSSHQPVAWPNPREIAHLGNADMIQPGLIPLQPNLDFMDTFEPFQDLFSSSRSIFGSM-- 346
           L S Q V   N   +A LG    ++ G +PL    +F     P       S S+  S+  
Sbjct: 162 LDSRQGVGEKNTFILATLGTGVPVE-GTLPLVTT-NFSPLPAPICPPAPGSASVPHSVPD 219

Query: 347 ---LPASASAPVPDPNNPPAQESI-LPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHT 402
              +P S  APVP     P Q +  +P  + P   +P    APP+ P+L   D      +
Sbjct: 220 AFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLIS-DSNPLSVS 278

Query: 403 SRTEDPFIQPTDFGPSEP-PLSVPQPFLPVFTMPLLSPSPAP---------PPISPVLPL 452
           +    P   P    PS P PLS P P       PL  P  AP         PP +P L L
Sbjct: 279 ASVLVPV--PASAPPSGPVPLSAPAP------APLSVPVSAPPLALIQAPVPPSAPTLVL 330

Query: 453 VPPPATALNP---------PAPPT--FHQPQKFAGVNKAPSVITHTASATLTHDAPATTF 501
            P P   L P         PAPP+     P   +G    P++I   A   +    PA  F
Sbjct: 331 APVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIF 390

Query: 502 SQS-QGLVITTHHPAPSAA--PCGLALSPVTRPPQPRLTFVHPKPVSLTGG---RPKQPH 555
           + +   +   T    P++A  P   +LS V   P  +   +   P+S   G    P QP 
Sbjct: 391 TPAPTPMPAATPAAIPTSAPIPASFSLSRVCF-PAAQAPAMQKVPLSFQPGTVLTPSQPL 449

Query: 556 KIVPAPK-PEPVSL 568
             +P P   +P+S+
Sbjct: 450 VYIPPPSCGQPLSV 463



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 55/185 (29%), Positives = 73/185 (39%), Gaps = 34/185 (18%)

Query: 349 ASASAPVPDPNNPPAQESILPTTALPTV--SLPDSLIAPPTAPSLAHMDEQGCEHTSRTE 406
           A   APVP P+ P    + +PT  L  +  S P +  APP+ P        G   T    
Sbjct: 315 ALIQAPVP-PSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPST---- 369

Query: 407 DPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVPPPATALNPPAPP 466
            P + P  F P+  P   P    P+FT       PAP P    +P   P A   + P P 
Sbjct: 370 -PTLIPA-FAPTPVPAPTP---APIFT-------PAPTP----MPAATPAAIPTSAPIPA 413

Query: 467 TFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHPAPSAAPCGLALS 526
           +F   +      +AP++     S       P T  + SQ LV   + P PS   CG  LS
Sbjct: 414 SFSLSRVCFPAAQAPAMQKVPLSF-----QPGTVLTPSQPLV---YIPPPS---CGQPLS 462

Query: 527 PVTRP 531
             T P
Sbjct: 463 VATLP 467


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 56/223 (25%), Positives = 79/223 (35%), Gaps = 42/223 (18%)

Query: 356 PDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSR----------- 404
           PD N+     +++ TT +P+V+ P +     T P++  + +     +SR           
Sbjct: 94  PDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVAT 153

Query: 405 ---TEDPFIQPTDFGPSEPPLSVPQPFLPVFTMP----LLSPSPAPPPISPVLPLVPPPA 457
                 P  Q T   P  P  + P P  P  + P       P+P+    +P     PP  
Sbjct: 154 LAPVNSPAPQDTTAAPPTPSATTPAP--PSSSAPPETTAAPPTPSATTQAPPSSSAPPET 211

Query: 458 TALNP------PAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITT 511
           TA  P      PAPP+   P +       PS    T  A L+  AP  T         T 
Sbjct: 212 TAAPPTPPATTPAPPSSSAPPETTAAPPTPSA---TTPAPLSSSAPPET---------TA 259

Query: 512 HHPAPSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQP 554
             P PSA      L P +    P  T   P P + T   P  P
Sbjct: 260 VPPTPSAT----TLDPSSASAPPETTAAPPTPSATTPAPPSSP 298



 Score = 53.5 bits (127), Expect = 9e-07
 Identities = 64/257 (24%), Positives = 92/257 (35%), Gaps = 37/257 (14%)

Query: 290 SSHQPVAWPNPREIAHLG--NADMIQPGLIPLQ--PNLDFMD-----------TFEPFQD 334
           S + P  +PNP +       N+ ++ P L+     P++ F             TF P   
Sbjct: 77  SPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNA 136

Query: 335 LFSSSRSIFGSMLPASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHM 394
              SSR    +    +  APV  P   P   +  P T   T   P S  APP   +    
Sbjct: 137 TTISSRENVNTSSSVATLAPVNSP--APQDTTAAPPTPSATTPAPPSSSAPPETTAAPPT 194

Query: 395 DEQGCEHTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVP 454
                  ++ T+ P   P+   P E   + P P       P  +P+P P   +P      
Sbjct: 195 P------SATTQAP---PSSSAPPETTAAPPTP-------PATTPAP-PSSSAPPETTAA 237

Query: 455 PPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHP 514
           PP  +   PAP +   P +   V   PS  T   S+     AP  T +       TT  P
Sbjct: 238 PPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSA---SAPPETTAAPPTPSATTPAP 294

Query: 515 APSAAPCGLALSPVTRP 531
             S AP     +P+T P
Sbjct: 295 PSSPAPQETTAAPITTP 311



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 52/197 (26%), Positives = 70/197 (35%), Gaps = 44/197 (22%)

Query: 350 SASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPF 409
           SA+ P P  ++ P + +  P T   T   P S  APP   +            +    P 
Sbjct: 173 SATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTA------------APPTPPA 220

Query: 410 IQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPL------------VPPPA 457
             P     S PP +   P  P  T P    S APP  + V P              PP  
Sbjct: 221 TTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPET 280

Query: 458 TALNP------PAPPTFHQPQKFAGV-----NKAPSVI---THTASATLTHDAPATTFSQ 503
           TA  P      PAPP+   PQ+         N +P+ +   T   SA  TH    +  +Q
Sbjct: 281 TAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTHQTTTSVTTQ 340

Query: 504 SQGLVITTHHPAPSAAP 520
                 TT    P++AP
Sbjct: 341 ------TTTTKQPTSAP 351



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 68/272 (25%), Positives = 97/272 (35%), Gaps = 38/272 (13%)

Query: 451 PLVPPPATALNPPAPPTFHQPQKFAGVNKA------------PSVITHTASATLTHDAPA 498
           P +PP     NPP  P  HQP K    N +            PSV   +AS  +T   P 
Sbjct: 72  PKLPPSPN--NPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKIT-TLPN 128

Query: 499 TTFSQSQGLVITTHHPAPSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQ--PHK 556
            TF       I++     +++     L+PV  P     T   P P + T   P    P +
Sbjct: 129 VTFLPQNATTISSRENVNTSSSVA-TLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPE 187

Query: 557 IVPAPKPEPVSLVLKNARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAI 616
              AP P P +        AP + S  P+    T+ P        +  S S    AP   
Sbjct: 188 TTAAP-PTPSATTQ-----APPSSSAPPET---TAAPPTPPATTPAPPSSS----APPET 234

Query: 617 ARAPGVPEFHSSILVTDLG--HGTSSPPAP-VSRLFPSTAQDPLGKGEQVPLHGGSPQVT 673
             AP  P   +   ++       T+ PP P  + L PS+A  P       P    +   T
Sbjct: 235 TAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSAT---T 291

Query: 674 VTGPSRDCPNSGQASPCAS-EQSPSPQSPQNN 704
              PS   P    A+P  +   SP+  +P  +
Sbjct: 292 PAPPSSPAPQETTAAPITTPNSSPTTLAPDTS 323


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 56/223 (25%), Positives = 79/223 (35%), Gaps = 42/223 (18%)

Query: 356 PDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSR----------- 404
           PD N+     +++ TT +P+V+ P +     T P++  + +     +SR           
Sbjct: 94  PDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVAT 153

Query: 405 ---TEDPFIQPTDFGPSEPPLSVPQPFLPVFTMP----LLSPSPAPPPISPVLPLVPPPA 457
                 P  Q T   P  P  + P P  P  + P       P+P+    +P     PP  
Sbjct: 154 LAPVNSPAPQDTTAAPPTPSATTPAP--PSSSAPPETTAAPPTPSATTQAPPSSSAPPET 211

Query: 458 TALNP------PAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITT 511
           TA  P      PAPP+   P +       PS    T  A L+  AP  T         T 
Sbjct: 212 TAAPPTPPATTPAPPSSSAPPETTAAPPTPSA---TTPAPLSSSAPPET---------TA 259

Query: 512 HHPAPSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQP 554
             P PSA      L P +    P  T   P P + T   P  P
Sbjct: 260 VPPTPSAT----TLDPSSASAPPETTAAPPTPSATTPAPPSSP 298



 Score = 53.5 bits (127), Expect = 9e-07
 Identities = 64/257 (24%), Positives = 92/257 (35%), Gaps = 37/257 (14%)

Query: 290 SSHQPVAWPNPREIAHLG--NADMIQPGLIPLQ--PNLDFMD-----------TFEPFQD 334
           S + P  +PNP +       N+ ++ P L+     P++ F             TF P   
Sbjct: 77  SPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNA 136

Query: 335 LFSSSRSIFGSMLPASASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHM 394
              SSR    +    +  APV  P   P   +  P T   T   P S  APP   +    
Sbjct: 137 TTISSRENVNTSSSVATLAPVNSP--APQDTTAAPPTPSATTPAPPSSSAPPETTAAPPT 194

Query: 395 DEQGCEHTSRTEDPFIQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPLVP 454
                  ++ T+ P   P+   P E   + P P       P  +P+P P   +P      
Sbjct: 195 P------SATTQAP---PSSSAPPETTAAPPTP-------PATTPAP-PSSSAPPETTAA 237

Query: 455 PPATALNPPAPPTFHQPQKFAGVNKAPSVITHTASATLTHDAPATTFSQSQGLVITTHHP 514
           PP  +   PAP +   P +   V   PS  T   S+     AP  T +       TT  P
Sbjct: 238 PPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSA---SAPPETTAAPPTPSATTPAP 294

Query: 515 APSAAPCGLALSPVTRP 531
             S AP     +P+T P
Sbjct: 295 PSSPAPQETTAAPITTP 311



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 52/197 (26%), Positives = 70/197 (35%), Gaps = 44/197 (22%)

Query: 350 SASAPVPDPNNPPAQESILPTTALPTVSLPDSLIAPPTAPSLAHMDEQGCEHTSRTEDPF 409
           SA+ P P  ++ P + +  P T   T   P S  APP   +            +    P 
Sbjct: 173 SATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTA------------APPTPPA 220

Query: 410 IQPTDFGPSEPPLSVPQPFLPVFTMPLLSPSPAPPPISPVLPL------------VPPPA 457
             P     S PP +   P  P  T P    S APP  + V P              PP  
Sbjct: 221 TTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPET 280

Query: 458 TALNP------PAPPTFHQPQKFAGV-----NKAPSVI---THTASATLTHDAPATTFSQ 503
           TA  P      PAPP+   PQ+         N +P+ +   T   SA  TH    +  +Q
Sbjct: 281 TAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTHQTTTSVTTQ 340

Query: 504 SQGLVITTHHPAPSAAP 520
                 TT    P++AP
Sbjct: 341 ------TTTTKQPTSAP 351



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 68/272 (25%), Positives = 97/272 (35%), Gaps = 38/272 (13%)

Query: 451 PLVPPPATALNPPAPPTFHQPQKFAGVNKA------------PSVITHTASATLTHDAPA 498
           P +PP     NPP  P  HQP K    N +            PSV   +AS  +T   P 
Sbjct: 72  PKLPPSPN--NPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKIT-TLPN 128

Query: 499 TTFSQSQGLVITTHHPAPSAAPCGLALSPVTRPPQPRLTFVHPKPVSLTGGRPKQ--PHK 556
            TF       I++     +++     L+PV  P     T   P P + T   P    P +
Sbjct: 129 VTFLPQNATTISSRENVNTSSSVA-TLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPE 187

Query: 557 IVPAPKPEPVSLVLKNARIAPAAFSGQPQAVIMTSGPLKREGMLASTVSQSNVVIAPAAI 616
              AP P P +        AP + S  P+    T+ P        +  S S    AP   
Sbjct: 188 TTAAP-PTPSATTQ-----APPSSSAPPET---TAAPPTPPATTPAPPSSS----APPET 234

Query: 617 ARAPGVPEFHSSILVTDLG--HGTSSPPAP-VSRLFPSTAQDPLGKGEQVPLHGGSPQVT 673
             AP  P   +   ++       T+ PP P  + L PS+A  P       P    +   T
Sbjct: 235 TAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSAT---T 291

Query: 674 VTGPSRDCPNSGQASPCAS-EQSPSPQSPQNN 704
              PS   P    A+P  +   SP+  +P  +
Sbjct: 292 PAPPSSPAPQETTAAPITTPNSSPTTLAPDTS 323


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,625,173
Number of Sequences: 37866
Number of extensions: 2829532
Number of successful extensions: 35932
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 274
Number of HSP's successfully gapped in prelim test: 1048
Number of HSP's that attempted gapping in prelim test: 20707
Number of HSP's gapped (non-prelim): 10076
length of query: 919
length of database: 18,247,518
effective HSP length: 111
effective length of query: 808
effective length of database: 14,044,392
effective search space: 11347868736
effective search space used: 11347868736
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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