Search of human proteins with 169178850

Search of human proteins with 169178850

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169178850 PREDICTED: similar to coiled-coil domain
containing 29 [Homo sapiens]
         (197 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169178850 PREDICTED: similar to coiled-coil domain containing...   389   e-108
gi|169217383 PREDICTED: similar to coiled-coil domain containing...   300   4e-82
gi|149363632 coiled-coil domain containing 29 [Homo sapiens]          271   3e-73
gi|239743762 PREDICTED: hypothetical protein XP_002342954 [Homo ...   270   4e-73
gi|239750312 PREDICTED: similar to hCG1744891 [Homo sapiens]          268   2e-72
gi|239747109 PREDICTED: hypothetical protein XP_002344496 [Homo ...   257   4e-69
gi|239742325 PREDICTED: similar to coiled-coil domain containing...   229   9e-61
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]      221   4e-58
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]      221   4e-58
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]      221   4e-58
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]      214   3e-56
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]      214   3e-56
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]      214   3e-56
gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens]    170   8e-43
gi|154354990 ankyrin repeat domain 26 [Homo sapiens]                  148   3e-36
gi|169169660 PREDICTED: hypothetical protein [Homo sapiens]           102   3e-22
gi|169169929 PREDICTED: hypothetical protein [Homo sapiens]           102   3e-22
gi|149363642 coiled-coil domain containing 144A [Homo sapiens]         84   1e-16
gi|50083279 centrosome protein 4 [Homo sapiens]                        50   9e-07
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    50   2e-06
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    50   2e-06
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...    48   5e-06
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ...    48   5e-06
gi|71061468 centromere protein E [Homo sapiens]                        47   8e-06
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...    47   8e-06
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    47   1e-05
gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens]     45   3e-05
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]    45   4e-05
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...    45   4e-05
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...    45   4e-05

>gi|169178850 PREDICTED: similar to coiled-coil domain containing 29
           [Homo sapiens]
          Length = 197

 Score =  389 bits (998), Expect = e-108
 Identities = 197/197 (100%), Positives = 197/197 (100%)

Query: 1   MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
           MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ
Sbjct: 1   MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60

Query: 61  VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
           VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ
Sbjct: 61  VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120

Query: 121 AVEKLKEIHLQMELDCVEQIIRETKRTVAVLDTCCHLLSSLESTVYQGPGQCGALVAWSL 180
           AVEKLKEIHLQMELDCVEQIIRETKRTVAVLDTCCHLLSSLESTVYQGPGQCGALVAWSL
Sbjct: 121 AVEKLKEIHLQMELDCVEQIIRETKRTVAVLDTCCHLLSSLESTVYQGPGQCGALVAWSL 180

Query: 181 VSEGLVRGGSVSWRIVQ 197
           VSEGLVRGGSVSWRIVQ
Sbjct: 181 VSEGLVRGGSVSWRIVQ 197


>gi|169217383 PREDICTED: similar to coiled-coil domain containing 29
           [Homo sapiens]
          Length = 185

 Score =  300 bits (769), Expect = 4e-82
 Identities = 153/164 (93%), Positives = 159/164 (96%)

Query: 1   MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
           MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDL  EEEAVSSKCVNL+KDNQ
Sbjct: 1   MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ 60

Query: 61  VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
           VIQQELLSMKKVQQECEKLEE++KMLEEEILNLKTHMEN+MVELSKLQEYKSE DERA+Q
Sbjct: 61  VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQ 120

Query: 121 AVEKLKEIHLQMELDCVEQIIRETKRTVAVLDTCCHLLSSLEST 164
           AVEKL+EIHLQME DCVEQIIRETKRTVAVLDTC HLLSSLEST
Sbjct: 121 AVEKLEEIHLQMEADCVEQIIRETKRTVAVLDTCSHLLSSLEST 164


>gi|149363632 coiled-coil domain containing 29 [Homo sapiens]
          Length = 161

 Score =  271 bits (693), Expect = 3e-73
 Identities = 136/161 (84%), Positives = 151/161 (93%)

Query: 1   MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
           MTINMLNVFGNEDF CH DLKTDQLKMDILIKKLKQKFDDL A++EA+SSKCVNL+KDNQ
Sbjct: 1   MTINMLNVFGNEDFDCHGDLKTDQLKMDILIKKLKQKFDDLTAQKEALSSKCVNLAKDNQ 60

Query: 61  VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
           V+QQE LSMKKVQQ+CEKLEE++KML+EEILNLKTHMEN+ VE+SKLQEYK ELDE+AMQ
Sbjct: 61  VLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVEISKLQEYKLELDEKAMQ 120

Query: 121 AVEKLKEIHLQMELDCVEQIIRETKRTVAVLDTCCHLLSSL 161
           AVEKL+EIHLQMELDCVEQI RETKR VAVL+TC  LL+SL
Sbjct: 121 AVEKLEEIHLQMELDCVEQITRETKRIVAVLNTCSRLLTSL 161


>gi|239743762 PREDICTED: hypothetical protein XP_002342954 [Homo
           sapiens]
          Length = 183

 Score =  270 bits (691), Expect = 4e-73
 Identities = 136/161 (84%), Positives = 150/161 (93%)

Query: 1   MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
           MTINMLNVFGNEDF CH DLK DQLKMDILIKKLKQKFDDL AE+EA+SSKCVNL+KDNQ
Sbjct: 23  MTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQ 82

Query: 61  VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
           V+QQE LSMKKVQQ+CEKLEE++KML+EEILNLKTHMEN+ VELSKLQEYK ELDE+AMQ
Sbjct: 83  VLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQ 142

Query: 121 AVEKLKEIHLQMELDCVEQIIRETKRTVAVLDTCCHLLSSL 161
           AVEK++EIHLQMELDCVEQI RETKR VAVL+TC  LL+SL
Sbjct: 143 AVEKIEEIHLQMELDCVEQITRETKRIVAVLNTCSRLLTSL 183


>gi|239750312 PREDICTED: similar to hCG1744891 [Homo sapiens]
          Length = 154

 Score =  268 bits (686), Expect = 2e-72
 Identities = 136/147 (92%), Positives = 143/147 (97%)

Query: 1   MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
           MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDL  EEEAVSSKCVNL+KDNQ
Sbjct: 1   MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ 60

Query: 61  VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
           VIQQELLSMKKVQQECEKLEE++KMLEEEILNLKTHMEN+MVELSKLQEYKSE DERA+Q
Sbjct: 61  VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSEPDERAIQ 120

Query: 121 AVEKLKEIHLQMELDCVEQIIRETKRT 147
           AVEKL+EIHLQME DCVEQIIRETKR+
Sbjct: 121 AVEKLEEIHLQMEADCVEQIIRETKRS 147


>gi|239747109 PREDICTED: hypothetical protein XP_002344496 [Homo
           sapiens]
          Length = 146

 Score =  257 bits (657), Expect = 4e-69
 Identities = 133/139 (95%), Positives = 135/139 (97%), Gaps = 2/139 (1%)

Query: 1   MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
           MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ
Sbjct: 1   MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60

Query: 61  VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
           VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ
Sbjct: 61  VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120

Query: 121 AVEKLKEIHLQMELDCVEQ 139
           AVEKLKEIHLQ  + C+ Q
Sbjct: 121 AVEKLKEIHLQ--VTCLNQ 137


>gi|239742325 PREDICTED: similar to coiled-coil domain containing 29
           [Homo sapiens]
          Length = 150

 Score =  229 bits (585), Expect = 9e-61
 Identities = 117/128 (91%), Positives = 124/128 (96%)

Query: 37  KFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 96
           +FDDLMAEEEAVSSKCVNL+KDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH
Sbjct: 2   RFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 61

Query: 97  MENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQMELDCVEQIIRETKRTVAVLDTCCH 156
           MENS+VELS+LQ+YKSELDERAMQAVEKLKEI+L ME DC+EQIIRETKRT AVLDTC H
Sbjct: 62  MENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRETKRTAAVLDTCSH 121

Query: 157 LLSSLEST 164
           LLSSLEST
Sbjct: 122 LLSSLEST 129


>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
          Length = 1363

 Score =  221 bits (562), Expect = 4e-58
 Identities = 110/151 (72%), Positives = 129/151 (85%)

Query: 1   MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
           MTINMLN F NEDF CH DL TDQLKMDIL KKLKQKFDDLMAE+EAVSSKCVNL+KDN+
Sbjct: 821 MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDNE 880

Query: 61  VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
           V+ QELLSM KVQ++CEKLE+++KMLEE++LNLKTHME  MVEL K+QEYKSELDERAMQ
Sbjct: 881 VLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQ 940

Query: 121 AVEKLKEIHLQMELDCVEQIIRETKRTVAVL 151
           A+EKL+EIHLQ + +  +Q+ +  K   A L
Sbjct: 941 AIEKLEEIHLQKQAEYEKQLEQLNKDNTASL 971



 Score = 29.3 bits (64), Expect = 2.3
 Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 5/112 (4%)

Query: 18  EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
           +D ++   K D +      K D  M +EE  + K  +L K+ + I QE+ S+ ++    E
Sbjct: 420 QDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYI-QEIKSITEINANFE 478

Query: 78  K-LEENQKMLEEEILNLKTHMENSMVELSKLQ---EYKSELDERAMQAVEKL 125
           K +  N++M+ +++      + +   E ++L    E +    ER    VE L
Sbjct: 479 KSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESL 530


>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
          Length = 1366

 Score =  221 bits (562), Expect = 4e-58
 Identities = 110/151 (72%), Positives = 129/151 (85%)

Query: 1    MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
            MTINMLN F NEDF CH DL TDQLKMDIL KKLKQKFDDLMAE+EAVSSKCVNL+KDN+
Sbjct: 850  MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDNE 909

Query: 61   VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
            V+ QELLSM KVQ++CEKLE+++KMLEE++LNLKTHME  MVEL K+QEYKSELDERAMQ
Sbjct: 910  VLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQ 969

Query: 121  AVEKLKEIHLQMELDCVEQIIRETKRTVAVL 151
            A+EKL+EIHLQ + +  +Q+ +  K   A L
Sbjct: 970  AIEKLEEIHLQKQAEYEKQLEQLNKDNTASL 1000



 Score = 29.3 bits (64), Expect = 2.3
 Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 5/112 (4%)

Query: 18  EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
           +D ++   K D +      K D  M +EE  + K  +L K+ + I QE+ S+ ++    E
Sbjct: 449 QDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYI-QEIKSITEINANFE 507

Query: 78  K-LEENQKMLEEEILNLKTHMENSMVELSKLQ---EYKSELDERAMQAVEKL 125
           K +  N++M+ +++      + +   E ++L    E +    ER    VE L
Sbjct: 508 KSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESL 559


>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
          Length = 1139

 Score =  221 bits (562), Expect = 4e-58
 Identities = 110/151 (72%), Positives = 129/151 (85%)

Query: 1    MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
            MTINMLN F NEDF CH DL TDQLKMDIL KKLKQKFDDLMAE+EAVSSKCVNL+KDN+
Sbjct: 850  MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDNE 909

Query: 61   VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
            V+ QELLSM KVQ++CEKLE+++KMLEE++LNLKTHME  MVEL K+QEYKSELDERAMQ
Sbjct: 910  VLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQ 969

Query: 121  AVEKLKEIHLQMELDCVEQIIRETKRTVAVL 151
            A+EKL+EIHLQ + +  +Q+ +  K   A L
Sbjct: 970  AIEKLEEIHLQKQAEYEKQLEQLNKDNTASL 1000



 Score = 29.3 bits (64), Expect = 2.3
 Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 5/112 (4%)

Query: 18  EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
           +D ++   K D +      K D  M +EE  + K  +L K+ + I QE+ S+ ++    E
Sbjct: 449 QDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYI-QEIKSITEINANFE 507

Query: 78  K-LEENQKMLEEEILNLKTHMENSMVELSKLQ---EYKSELDERAMQAVEKL 125
           K +  N++M+ +++      + +   E ++L    E +    ER    VE L
Sbjct: 508 KSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESL 559


>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
          Length = 1415

 Score =  214 bits (546), Expect = 3e-56
 Identities = 106/151 (70%), Positives = 128/151 (84%)

Query: 1   MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
           MTINMLN F NEDF CH DL TDQLKMDIL KKLKQKF+DL+AE+EAVSS+CVNL+KDN+
Sbjct: 820 MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNE 879

Query: 61  VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
           V+ QELLSM+ VQ++CEKLE+++KMLEEE+LNLKTHME  MVEL KLQEYKSELDERA+Q
Sbjct: 880 VLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQ 939

Query: 121 AVEKLKEIHLQMELDCVEQIIRETKRTVAVL 151
            +EKL+EIHLQ + +  +Q+ +  K   A L
Sbjct: 940 EIEKLEEIHLQKQAEYEKQLEQLNKDNTASL 970



 Score = 30.4 bits (67), Expect = 1.0
 Identities = 28/112 (25%), Positives = 51/112 (45%), Gaps = 5/112 (4%)

Query: 18  EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
           +D ++   K D +      K D  M +EE  + K  +L K+ + I QE+ S+ ++    E
Sbjct: 419 QDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYI-QEIKSITEINANFE 477

Query: 78  K-LEENQKMLEEEILNLKTHMENSMVELSKLQ---EYKSELDERAMQAVEKL 125
           K +  N+KM+ + +      + +   E ++L    E +    ER    VE L
Sbjct: 478 KSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESL 529


>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
          Length = 1002

 Score =  214 bits (546), Expect = 3e-56
 Identities = 106/151 (70%), Positives = 128/151 (84%)

Query: 1   MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
           MTINMLN F NEDF CH DL TDQLKMDIL KKLKQKF+DL+AE+EAVSS+CVNL+KDN+
Sbjct: 713 MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNE 772

Query: 61  VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
           V+ QELLSM+ VQ++CEKLE+++KMLEEE+LNLKTHME  MVEL KLQEYKSELDERA+Q
Sbjct: 773 VLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQ 832

Query: 121 AVEKLKEIHLQMELDCVEQIIRETKRTVAVL 151
            +EKL+EIHLQ + +  +Q+ +  K   A L
Sbjct: 833 EIEKLEEIHLQKQAEYEKQLEQLNKDNTASL 863



 Score = 30.4 bits (67), Expect = 1.0
 Identities = 28/112 (25%), Positives = 51/112 (45%), Gaps = 5/112 (4%)

Query: 18  EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
           +D ++   K D +      K D  M +EE  + K  +L K+ + I QE+ S+ ++    E
Sbjct: 312 QDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYI-QEIKSITEINANFE 370

Query: 78  K-LEENQKMLEEEILNLKTHMENSMVELSKLQ---EYKSELDERAMQAVEKL 125
           K +  N+KM+ + +      + +   E ++L    E +    ER    VE L
Sbjct: 371 KSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESL 422


>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
          Length = 1415

 Score =  214 bits (546), Expect = 3e-56
 Identities = 106/151 (70%), Positives = 128/151 (84%)

Query: 1   MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
           MTINMLN F NEDF CH DL TDQLKMDIL KKLKQKF+DL+AE+EAVSS+CVNL+KDN+
Sbjct: 820 MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNE 879

Query: 61  VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
           V+ QELLSM+ VQ++CEKLE+++KMLEEE+LNLKTHME  MVEL KLQEYKSELDERA+Q
Sbjct: 880 VLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQ 939

Query: 121 AVEKLKEIHLQMELDCVEQIIRETKRTVAVL 151
            +EKL+EIHLQ + +  +Q+ +  K   A L
Sbjct: 940 EIEKLEEIHLQKQAEYEKQLEQLNKDNTASL 970



 Score = 30.4 bits (67), Expect = 1.0
 Identities = 28/112 (25%), Positives = 51/112 (45%), Gaps = 5/112 (4%)

Query: 18  EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
           +D ++   K D +      K D  M +EE  + K  +L K+ + I QE+ S+ ++    E
Sbjct: 419 QDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYI-QEIKSITEINANFE 477

Query: 78  K-LEENQKMLEEEILNLKTHMENSMVELSKLQ---EYKSELDERAMQAVEKL 125
           K +  N+KM+ + +      + +   E ++L    E +    ER    VE L
Sbjct: 478 KSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESL 529


>gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens]
          Length = 561

 Score =  170 bits (430), Expect = 8e-43
 Identities = 86/108 (79%), Positives = 100/108 (92%)

Query: 33  KLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILN 92
           +++ +FDD MAE+EAVSSKCVNL+K+ QV QQELLSMKKVQQECEKLEE++KMLEEEILN
Sbjct: 443 QVESQFDDFMAEKEAVSSKCVNLAKEIQVFQQELLSMKKVQQECEKLEEDKKMLEEEILN 502

Query: 93  LKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQMELDCVEQI 140
           LKTHMENSMVELSKLQEYKSELDERAMQAVEKL+EIHLQ + +  +Q+
Sbjct: 503 LKTHMENSMVELSKLQEYKSELDERAMQAVEKLEEIHLQEQAEHKKQL 550


>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
          Length = 1710

 Score =  148 bits (374), Expect = 3e-36
 Identities = 72/140 (51%), Positives = 103/140 (73%), Gaps = 1/140 (0%)

Query: 1    MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
            MT   LN + N +F  H DLKT Q +MDI I KLK K DDL AE E   SKC++L   NQ
Sbjct: 1369 MTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQ 1428

Query: 61   VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
            ++Q+ELLSMK VQ++CEKL++N+K LE+E++NL++H+E +MVEL ++++YK E++ERA Q
Sbjct: 1429 ILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQ 1488

Query: 121  AV-EKLKEIHLQMELDCVEQ 139
             + EKLKE++L ++     Q
Sbjct: 1489 EIAEKLKEVNLFLQAQAASQ 1508



 Score = 32.7 bits (73), Expect = 0.20
 Identities = 31/113 (27%), Positives = 52/113 (46%), Gaps = 11/113 (9%)

Query: 31   IKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQEC---EKLEENQKMLE 87
            +K+ KQ+ ++   +E A   K VNL    Q   QE L   +         ++E   K LE
Sbjct: 1475 VKQYKQEIEERARQEIAEKLKEVNLFLQAQAASQENLEQFRENNFASMKSQMELRIKDLE 1534

Query: 88   EEILNLKTHMEN-SMVELSK-----LQEYK--SELDERAMQAVEKLKEIHLQM 132
             E+  +KT  E+ +  EL K     L+E K    L  +  +  E+L E++ ++
Sbjct: 1535 SELSKIKTSQEDFNKTELEKYKQLYLEELKVRKSLSSKLTKTNERLAEVNTKL 1587



 Score = 31.2 bits (69), Expect = 0.60
 Identities = 24/120 (20%), Positives = 55/120 (45%), Gaps = 10/120 (8%)

Query: 16   CHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQE 75
            C EDLK  + K + L K +KQ  + L       + +   L+ +N ++  +L         
Sbjct: 942  CFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKL--------- 992

Query: 76   CEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQMELD 135
             E  +++++ LE E+ +  + +  ++ +  + +  K EL+    +A ++   +  +M  D
Sbjct: 993  -ENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFD 1051



 Score = 31.2 bits (69), Expect = 0.60
 Identities = 29/129 (22%), Positives = 60/129 (46%), Gaps = 13/129 (10%)

Query: 18   EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
            +DLK    ++   +++ + +  + +   E +      L KDN  ++        V+++ +
Sbjct: 1257 QDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLK------VTVKKQMD 1310

Query: 78   KLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQMELDCV 137
            K+EE QK L    L+     E+   +L KL E K  L+    Q  E  K + L+ E+   
Sbjct: 1311 KIEELQKNLLNANLS-----EDEKEQLKKLMELKQSLECNLDQ--EMKKNVELEREITGF 1363

Query: 138  EQIIRETKR 146
            + +++ T++
Sbjct: 1364 KNLLKMTRK 1372



 Score = 28.1 bits (61), Expect = 5.0
 Identities = 30/135 (22%), Positives = 62/135 (45%), Gaps = 4/135 (2%)

Query: 24   QLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE-KLEEN 82
            Q ++++  KK+  +      EE+ +S K   L ++  +++ E+ ++K   QE E K  E+
Sbjct: 886  QKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFED 945

Query: 83   QKMLEEEILNL-KTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQMELDCVEQII 141
             K+++E+  +L KT  +N       + +Y   L    + A   +    L+ E    E++ 
Sbjct: 946  LKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLS--VLTAENAMLNSKLENEKQSKERLE 1003

Query: 142  RETKRTVAVLDTCCH 156
             E +   + L    H
Sbjct: 1004 AEVESYHSRLAAAIH 1018


>gi|169169660 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 460

 Score =  102 bits (253), Expect = 3e-22
 Identities = 54/100 (54%), Positives = 75/100 (75%), Gaps = 1/100 (1%)

Query: 32  KKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEIL 91
           K L++   +L    +    KC+ L+K NQVIQQELLSMK+VQQ+C+KLEE  K+LE+E++
Sbjct: 316 KFLRRHLMNLQQSWKLYLQKCLYLAKKNQVIQQELLSMKEVQQKCKKLEEVNKILEQEVV 375

Query: 92  NLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQ 131
           NLKTH E +MVE   ++E K +L+ERA Q +EKL+EI+LQ
Sbjct: 376 NLKTH-EKNMVEFGDVEECKLQLEERAGQEIEKLEEINLQ 414


>gi|169169929 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 460

 Score =  102 bits (253), Expect = 3e-22
 Identities = 54/100 (54%), Positives = 75/100 (75%), Gaps = 1/100 (1%)

Query: 32  KKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEIL 91
           K L++   +L    +    KC+ L+K NQVIQQELLSMK+VQQ+C+KLEE  K+LE+E++
Sbjct: 316 KFLRRHLMNLQQSWKLYLQKCLYLAKKNQVIQQELLSMKEVQQKCKKLEEVNKILEQEVV 375

Query: 92  NLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQ 131
           NLKTH E +MVE   ++E K +L+ERA Q +EKL+EI+LQ
Sbjct: 376 NLKTH-EKNMVEFGDVEECKLQLEERAGQEIEKLEEINLQ 414


>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
          Length = 1427

 Score = 83.6 bits (205), Expect = 1e-16
 Identities = 50/147 (34%), Positives = 89/147 (60%), Gaps = 7/147 (4%)

Query: 26   KMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQ--QELLSMKKVQQECEKLEENQ 83
            +MD   K+   +  DL   +E V S+C++L  +N+V+Q  Q L SMK +Q++CE L++N+
Sbjct: 1112 RMDQCEKEKAGRKIDLTEAQETVPSRCLHLDAENEVLQLQQTLFSMKAIQKQCETLQKNK 1171

Query: 84   KMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAV-EKLKEIHLQMELDCV---EQ 139
            K L++E++NLK++ME +M+E  K + +K  ++ERA + + EKL E  L ++       EQ
Sbjct: 1172 KQLKQEVVNLKSYMERNMLERGKAEWHKLLIEERARKEIEEKLNEAILTLQKQAAVSHEQ 1231

Query: 140  IIRETKRTVAVLDTCCHL-LSSLESTV 165
            +++  +     + T   L +  LES +
Sbjct: 1232 LVQLREDNTTSIKTQMELTIKDLESEI 1258



 Score = 33.9 bits (76), Expect = 0.092
 Identities = 24/95 (25%), Positives = 47/95 (49%), Gaps = 1/95 (1%)

Query: 11  NEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELL-SM 69
           +ED +  E++   +L++D +  + KQK      + EAV  K  NL K  ++ ++ L  ++
Sbjct: 819 HEDCMLQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKNDNLQKIIKLNEETLTETI 878

Query: 70  KKVQQECEKLEENQKMLEEEILNLKTHMENSMVEL 104
            +   +   L    K+L  E+ N K + E   +E+
Sbjct: 879 LQYSGQLNNLTAENKILNSELENGKQNQERLEIEM 913



 Score = 28.9 bits (63), Expect = 3.0
 Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 21/136 (15%)

Query: 18  EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
           ED++  + K D L K +K   + L       S +  NL+ +N+++  EL + K+ Q+  E
Sbjct: 851 EDIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNLTAENKILNSELENGKQNQERLE 910

Query: 78  ---------------KLEENQKMLEEEILNLKTHME------NSMVELSKLQEYKSELDE 116
                            +++Q   + ++   +T  E         V++S LQ     L E
Sbjct: 911 IEMESYRCRLAAAVRDCDQSQTARDLKLDFQRTRQEWVRLHDKMKVDMSGLQAKNEILSE 970

Query: 117 RAMQAVEKLKEIHLQM 132
           +   A  K+  + +Q+
Sbjct: 971 KLSNAESKINSLQIQL 986



 Score = 27.7 bits (60), Expect = 6.6
 Identities = 20/112 (17%), Positives = 51/112 (45%), Gaps = 7/112 (6%)

Query: 60   QVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAM 119
            Q+ Q E   +KK   + E +EE    L+ E + L+  ++++  + +  ++  S + ++  
Sbjct: 1019 QMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFH 1078

Query: 120  QAVEKLKEIHLQMELDCVEQIIRETKRTVAVLDTCCHLLSSLESTVYQGPGQ 171
             A + L       + +  +QI+   ++   ++D   HL   ++    +  G+
Sbjct: 1079 SAAKNL-------QAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAGR 1123


>gi|50083279 centrosome protein 4 [Homo sapiens]
          Length = 1140

 Score = 50.4 bits (119), Expect = 9e-07
 Identities = 36/144 (25%), Positives = 78/144 (54%), Gaps = 7/144 (4%)

Query: 11  NEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMK 70
           NE  + H +++ D L+     K L+++  +LM  +E V+S+ VNLS  N+ + QEL  + 
Sbjct: 266 NEKLIAHLNIQVDFLQQ--ANKDLEKRIRELMETKETVTSEVVNLSNKNEKLCQELTEID 323

Query: 71  KVQQECEK-LEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELD---ERAMQAVEKLK 126
           ++ Q+ E+  EE  +  ++E+   K  ++  + E+  L+E  ++L        +  E+L 
Sbjct: 324 QLAQQLERHKEEVLETADKELGEAKKEIKRKLSEMQDLEETMAKLQLELNLCQKEKERLS 383

Query: 127 -EIHLQMELDCVEQIIRETKRTVA 149
            E+ ++ +L+ V   + + K+ ++
Sbjct: 384 DELLVKSDLETVVHQLEQEKQRLS 407



 Score = 31.6 bits (70), Expect = 0.46
 Identities = 24/114 (21%), Positives = 53/114 (46%), Gaps = 3/114 (2%)

Query: 20  LKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKL 79
           LK   +  D  I  L+++ D    E + V        K+N+ +Q +L +M +  QE   L
Sbjct: 781 LKETLVNRDREINSLRRQLDAAHKELDEVGRSREIAFKENRRLQDDLATMARENQEI-SL 839

Query: 80  EENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQME 133
           E    + E+E   +K+ +   + E+S+ +   +  ++     +++ + +H + E
Sbjct: 840 ELEAAVQEKE--EMKSRVHKYITEVSRWESLMAAKEKENQDLLDRFQMLHNRAE 891



 Score = 28.9 bits (63), Expect = 3.0
 Identities = 33/126 (26%), Positives = 59/126 (46%), Gaps = 23/126 (18%)

Query: 31  IKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKK----VQQECEKLEENQKML 86
           IK L++K D+L            NL   +Q   +E   MKK    + +E + L+E     
Sbjct: 701 IKILEEKIDEL------------NLKMTSQ--DEEAHVMKKTIGVIDKEKDFLQETVDEK 746

Query: 87  EEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKL----KEIH-LQMELDCVEQII 141
            E+I NL+ ++ N    +++++   SE +    Q  E L    +EI+ L+ +LD   + +
Sbjct: 747 TEKIANLQENLANKEKAVAQMKIMISECESSVNQLKETLVNRDREINSLRRQLDAAHKEL 806

Query: 142 RETKRT 147
            E  R+
Sbjct: 807 DEVGRS 812



 Score = 28.1 bits (61), Expect = 5.0
 Identities = 19/97 (19%), Positives = 49/97 (50%), Gaps = 10/97 (10%)

Query: 26   KMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQE-------LLSMKKVQQECEK 78
            ++++L K++++  +   A E  +SS    +S+  + ++ +       L  +  +++ C K
Sbjct: 924  RVELLEKEIQEHINAHHAYESQISSMAKAMSRLEEELRHQEDEKATVLNDLSSLRELCIK 983

Query: 79   LEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELD 115
            L+  + ++ +++ +     E  +VE   L+  KSE D
Sbjct: 984  LDSGKDIMTQQLNSKNLEFERVVVE---LENVKSESD 1017



 Score = 27.7 bits (60), Expect = 6.6
 Identities = 28/135 (20%), Positives = 63/135 (46%), Gaps = 10/135 (7%)

Query: 26  KMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQV---IQQELLSMKKVQQECEKLEEN 82
           K  I  ++ + + D+ +   E VSS  V    D  +   +Q     ++++QQE  +L+E 
Sbjct: 161 KRSIAFRRQRMQIDEPVPPSE-VSSYPVPQPDDPYIADLLQVADNRIQELQQEVHQLQEK 219

Query: 83  QKMLEEEILNLKTHMENSMVELSKLQ---EYKSELDERAMQAVEKLKE---IHLQMELDC 136
             M+E  + +    +E    E+ +L    +     D  ++++  K  E    HL +++D 
Sbjct: 220 LAMMESGVRDYSKQIELREREIERLSVALDGGRSPDVLSLESRNKTNEKLIAHLNIQVDF 279

Query: 137 VEQIIRETKRTVAVL 151
           ++Q  ++ ++ +  L
Sbjct: 280 LQQANKDLEKRIREL 294


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
           sapiens]
          Length = 1843

 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 44/174 (25%), Positives = 83/174 (47%), Gaps = 18/174 (10%)

Query: 12  EDFVCHEDLKTDQLKMDIL------IKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQE 65
           E+ + HE +K    K+  +      IKK  + + +     E + ++  +L K+N+++Q++
Sbjct: 588 ENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKK 647

Query: 66  LLSMKKVQQECEKLEENQKMLEEEILNLKTHME---NSMVELSKLQEYKSELDERAMQA- 121
           + ++K   ++ E LE+    LE E   LK  ++   N   +L  L++  S+LDE  ++  
Sbjct: 648 ITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELR 707

Query: 122 --VEKL-----KEIHLQMELDCVEQIIRETKRTVAVLDTCCHLLSSLESTVYQG 168
             VE L     K   LQ+E   +E    + K+ + +L         LE + YQG
Sbjct: 708 RNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVS-YQG 760



 Score = 38.1 bits (87), Expect = 0.005
 Identities = 23/103 (22%), Positives = 55/103 (53%), Gaps = 1/103 (0%)

Query: 18  EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
           E L+     +DI  ++L++  ++   + + + S+  +L  +NQ +Q+ L  +K   +  E
Sbjct: 752 ERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLE 811

Query: 78  KLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
           +LE+  K LE+E   L+   +    E  +L++ ++E+ +  ++
Sbjct: 812 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQ-QAEIKDTTLE 853



 Score = 34.7 bits (78), Expect = 0.054
 Identities = 30/112 (26%), Positives = 64/112 (57%), Gaps = 9/112 (8%)

Query: 20  LKTDQLKMDILIKKLKQKFD--DLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
           L+ D+ +++   K+L+Q+ +  D   EE  V  K  NL K+N+ + +E+   K+     +
Sbjct: 827 LEKDKKQLEKENKRLRQQAEIKDTTLEENNV--KIGNLEKENKTLSKEIGIYKESCVRLK 884

Query: 78  KLE-ENQKMLEEEILNLKTHM---ENSMVELSKLQEYKSELDERAMQAVEKL 125
           +LE EN+++++   +++KT +   E+ + E  K Q+  ++L E+    +EK+
Sbjct: 885 ELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDL-EKLTHELEKI 935



 Score = 34.7 bits (78), Expect = 0.054
 Identities = 32/120 (26%), Positives = 52/120 (43%), Gaps = 14/120 (11%)

Query: 18   EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
            E L+TD   +  L+   K +   L AE           SK  +  QQ  ++  K+  +CE
Sbjct: 1262 EVLQTDHKNLKSLLNNSKLEQTRLEAE----------FSKLKEQYQQLDITSTKLNNQCE 1311

Query: 78   KLEENQKMLEEEILNLKTHMENSMVE----LSKLQEYKSELDERAMQAVEKLKEIHLQME 133
             L + +  LEEE  +L   ++  M++    L +  E K        Q ++KL E+  Q E
Sbjct: 1312 LLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKE 1371



 Score = 33.9 bits (76), Expect = 0.092
 Identities = 32/147 (21%), Positives = 75/147 (51%), Gaps = 21/147 (14%)

Query: 25  LKMDILIKKLKQKFDDLMAEEEAV---SSKCVNLSKDNQ-------VIQQELLSMKKVQQ 74
           LK+++  + L +  ++L    ++V   +SK + + K+NQ       +++ E++  K+  Q
Sbjct: 463 LKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQ 522

Query: 75  ECEKLEEN----QKMLEEEILNLKTHMENSMVELSK----LQEYKSELDERAMQAVE-KL 125
            C+ L ++    +  LE+ I  L+ + E  +  L +    L +  S L +R+  + E ++
Sbjct: 523 NCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARV 582

Query: 126 KEIHLQMELDCVEQIIRETKRTVAVLD 152
           K+I  + E   + + I+ET   ++ ++
Sbjct: 583 KDI--EKENKILHESIKETSSKLSKIE 607



 Score = 33.5 bits (75), Expect = 0.12
 Identities = 32/146 (21%), Positives = 67/146 (45%), Gaps = 16/146 (10%)

Query: 26  KMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKM 85
           K++  + + K++  D+    E   ++   L +DNQV+ +    ++   +      +    
Sbjct: 324 KLESEVSRYKERLHDI----EFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHE 379

Query: 86  LEEEILNLKTHMENSMVE-------LSKLQEYKSELDERAMQAVEKLKEIHLQMELDCVE 138
           LE+E L LK  + +  +E       + +L E    L+    Q+++  + +HL  EL   E
Sbjct: 380 LEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMD--ESLHLGWEL---E 434

Query: 139 QIIRETKRTVAVLDTCCHLLSSLEST 164
           QI R ++ + A   +  H ++ L S+
Sbjct: 435 QISRTSELSEAPQKSLGHEVNELTSS 460



 Score = 33.5 bits (75), Expect = 0.12
 Identities = 26/116 (22%), Positives = 59/116 (50%), Gaps = 6/116 (5%)

Query: 24  QLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQ 83
           Q+  +  +K ++++   L    +  SSK   +  + + I++EL   K+  +  E+LE   
Sbjct: 575 QISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENEL 634

Query: 84  KMLEE--EILNLK-THMENSMVELSKLQEYKSELD---ERAMQAVEKLKEIHLQME 133
             LE+  E+L  K T+++ +  ++  L++  SEL+    +  + ++  K +  Q+E
Sbjct: 635 HHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLE 690



 Score = 33.1 bits (74), Expect = 0.16
 Identities = 35/137 (25%), Positives = 68/137 (49%), Gaps = 17/137 (12%)

Query: 18  EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQ--- 74
           E L+ +  ++D    +L++  + L    +  S K   L  +N+ ++ E   +KK  +   
Sbjct: 690 ESLEKENSQLDEENLELRRNVESL----KCASMKMAQLQLENKELESEKEQLKKGLELLK 745

Query: 75  ----ECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAM--QAVEKLKEI 128
               + E+LE + + L+ E   L+  +ENS     K+Q+ +SEL +  M  Q ++K  E 
Sbjct: 746 ASFKKTERLEVSYQGLDIENQRLQKTLENSNK---KIQQLESELQDLEMENQTLQKNLE- 801

Query: 129 HLQMELDCVEQIIRETK 145
            L++    +EQ+ +E K
Sbjct: 802 ELKISSKRLEQLEKENK 818



 Score = 32.7 bits (73), Expect = 0.20
 Identities = 19/81 (23%), Positives = 45/81 (55%), Gaps = 4/81 (4%)

Query: 11   NEDFVCHEDLKTDQLKMDILIKKLKQKFD-DLMAEEEAVSSKCVNLSKD---NQVIQQEL 66
            N++ + H++  TD  +  +L  KL+      L  +EE +++    L +    NQ ++QEL
Sbjct: 938  NKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQEL 997

Query: 67   LSMKKVQQECEKLEENQKMLE 87
             ++KK  +  ++ ++ ++M++
Sbjct: 998  KTVKKNYEALKQRQDEERMVQ 1018



 Score = 28.9 bits (63), Expect = 3.0
 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 6/93 (6%)

Query: 26   KMDILIKKLKQKFDDLMAEE---EAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEEN 82
            +++ L K LK + + ++ E    E V+++   L  +N  +      + K   E E L+ +
Sbjct: 1211 QLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLK---ETEVLQTD 1267

Query: 83   QKMLEEEILNLKTHMENSMVELSKLQEYKSELD 115
             K L+  + N K        E SKL+E   +LD
Sbjct: 1268 HKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLD 1300



 Score = 28.5 bits (62), Expect = 3.9
 Identities = 24/109 (22%), Positives = 52/109 (47%), Gaps = 7/109 (6%)

Query: 60  QVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMV---ELSKLQEYKSELDE 116
           Q ++++   +   +QE E++E   K L++E +NL +   ++ +   EL  L+E    +D+
Sbjct: 265 QELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDK 324

Query: 117 RAMQAVEKLKEIHLQMELDCVEQIIRETKR-TVAVLDTCCHLLSSLEST 164
              +     + +H   +++  +  + E K     +L+T   L   LE T
Sbjct: 325 LESEVSRYKERLH---DIEFYKARVEELKEDNQVLLETKTMLEDQLEGT 370



 Score = 28.1 bits (61), Expect = 5.0
 Identities = 25/114 (21%), Positives = 51/114 (44%), Gaps = 5/114 (4%)

Query: 18   EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
            ++LKT +   + L  K +Q  + ++     +S +     +++Q   +ELL   KV+    
Sbjct: 995  QELKTVKKNYEAL--KQRQDEERMVQSSPPISGEDNKWERESQETTRELL---KVKDRLI 1049

Query: 78   KLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQ 131
            ++E N   L+ E   LKT ++    + + LQ     L  + +   E+   +  Q
Sbjct: 1050 EVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQ 1103


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
           sapiens]
          Length = 1870

 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 44/174 (25%), Positives = 83/174 (47%), Gaps = 18/174 (10%)

Query: 12  EDFVCHEDLKTDQLKMDIL------IKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQE 65
           E+ + HE +K    K+  +      IKK  + + +     E + ++  +L K+N+++Q++
Sbjct: 588 ENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKK 647

Query: 66  LLSMKKVQQECEKLEENQKMLEEEILNLKTHME---NSMVELSKLQEYKSELDERAMQA- 121
           + ++K   ++ E LE+    LE E   LK  ++   N   +L  L++  S+LDE  ++  
Sbjct: 648 ITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELR 707

Query: 122 --VEKL-----KEIHLQMELDCVEQIIRETKRTVAVLDTCCHLLSSLESTVYQG 168
             VE L     K   LQ+E   +E    + K+ + +L         LE + YQG
Sbjct: 708 RNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVS-YQG 760



 Score = 38.1 bits (87), Expect = 0.005
 Identities = 23/103 (22%), Positives = 55/103 (53%), Gaps = 1/103 (0%)

Query: 18  EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
           E L+     +DI  ++L++  ++   + + + S+  +L  +NQ +Q+ L  +K   +  E
Sbjct: 752 ERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLE 811

Query: 78  KLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
           +LE+  K LE+E   L+   +    E  +L++ ++E+ +  ++
Sbjct: 812 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQ-QAEIKDTTLE 853



 Score = 34.7 bits (78), Expect = 0.054
 Identities = 30/112 (26%), Positives = 64/112 (57%), Gaps = 9/112 (8%)

Query: 20  LKTDQLKMDILIKKLKQKFD--DLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
           L+ D+ +++   K+L+Q+ +  D   EE  V  K  NL K+N+ + +E+   K+     +
Sbjct: 827 LEKDKKQLEKENKRLRQQAEIKDTTLEENNV--KIGNLEKENKTLSKEIGIYKESCVRLK 884

Query: 78  KLE-ENQKMLEEEILNLKTHM---ENSMVELSKLQEYKSELDERAMQAVEKL 125
           +LE EN+++++   +++KT +   E+ + E  K Q+  ++L E+    +EK+
Sbjct: 885 ELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDL-EKLTHELEKI 935



 Score = 34.7 bits (78), Expect = 0.054
 Identities = 32/120 (26%), Positives = 52/120 (43%), Gaps = 14/120 (11%)

Query: 18   EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
            E L+TD   +  L+   K +   L AE           SK  +  QQ  ++  K+  +CE
Sbjct: 1261 EVLQTDHKNLKSLLNNSKLEQTRLEAE----------FSKLKEQYQQLDITSTKLNNQCE 1310

Query: 78   KLEENQKMLEEEILNLKTHMENSMVE----LSKLQEYKSELDERAMQAVEKLKEIHLQME 133
             L + +  LEEE  +L   ++  M++    L +  E K        Q ++KL E+  Q E
Sbjct: 1311 LLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKE 1370



 Score = 33.9 bits (76), Expect = 0.092
 Identities = 32/147 (21%), Positives = 75/147 (51%), Gaps = 21/147 (14%)

Query: 25  LKMDILIKKLKQKFDDLMAEEEAV---SSKCVNLSKDNQ-------VIQQELLSMKKVQQ 74
           LK+++  + L +  ++L    ++V   +SK + + K+NQ       +++ E++  K+  Q
Sbjct: 463 LKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQ 522

Query: 75  ECEKLEEN----QKMLEEEILNLKTHMENSMVELSK----LQEYKSELDERAMQAVE-KL 125
            C+ L ++    +  LE+ I  L+ + E  +  L +    L +  S L +R+  + E ++
Sbjct: 523 NCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARV 582

Query: 126 KEIHLQMELDCVEQIIRETKRTVAVLD 152
           K+I  + E   + + I+ET   ++ ++
Sbjct: 583 KDI--EKENKILHESIKETSSKLSKIE 607



 Score = 33.5 bits (75), Expect = 0.12
 Identities = 32/146 (21%), Positives = 67/146 (45%), Gaps = 16/146 (10%)

Query: 26  KMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKM 85
           K++  + + K++  D+    E   ++   L +DNQV+ +    ++   +      +    
Sbjct: 324 KLESEVSRYKERLHDI----EFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHE 379

Query: 86  LEEEILNLKTHMENSMVE-------LSKLQEYKSELDERAMQAVEKLKEIHLQMELDCVE 138
           LE+E L LK  + +  +E       + +L E    L+    Q+++  + +HL  EL   E
Sbjct: 380 LEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMD--ESLHLGWEL---E 434

Query: 139 QIIRETKRTVAVLDTCCHLLSSLEST 164
           QI R ++ + A   +  H ++ L S+
Sbjct: 435 QISRTSELSEAPQKSLGHEVNELTSS 460



 Score = 33.5 bits (75), Expect = 0.12
 Identities = 26/116 (22%), Positives = 59/116 (50%), Gaps = 6/116 (5%)

Query: 24  QLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQ 83
           Q+  +  +K ++++   L    +  SSK   +  + + I++EL   K+  +  E+LE   
Sbjct: 575 QISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENEL 634

Query: 84  KMLEE--EILNLK-THMENSMVELSKLQEYKSELD---ERAMQAVEKLKEIHLQME 133
             LE+  E+L  K T+++ +  ++  L++  SEL+    +  + ++  K +  Q+E
Sbjct: 635 HHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLE 690



 Score = 33.1 bits (74), Expect = 0.16
 Identities = 35/137 (25%), Positives = 68/137 (49%), Gaps = 17/137 (12%)

Query: 18  EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQ--- 74
           E L+ +  ++D    +L++  + L    +  S K   L  +N+ ++ E   +KK  +   
Sbjct: 690 ESLEKENSQLDEENLELRRNVESL----KCASMKMAQLQLENKELESEKEQLKKGLELLK 745

Query: 75  ----ECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAM--QAVEKLKEI 128
               + E+LE + + L+ E   L+  +ENS     K+Q+ +SEL +  M  Q ++K  E 
Sbjct: 746 ASFKKTERLEVSYQGLDIENQRLQKTLENSNK---KIQQLESELQDLEMENQTLQKNLE- 801

Query: 129 HLQMELDCVEQIIRETK 145
            L++    +EQ+ +E K
Sbjct: 802 ELKISSKRLEQLEKENK 818



 Score = 30.0 bits (66), Expect = 1.3
 Identities = 19/83 (22%), Positives = 46/83 (55%), Gaps = 9/83 (10%)

Query: 11   NEDFVCHEDLKTD------QLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQ 64
            N++ + H++  TD      + K++  +KK  +  ++ +A  EA   +  N    NQ ++Q
Sbjct: 938  NKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNY---NQQLRQ 994

Query: 65   ELLSMKKVQQECEKLEENQKMLE 87
            EL ++KK  +  ++ ++ ++M++
Sbjct: 995  ELKTVKKNYEALKQRQDEERMVQ 1017



 Score = 28.9 bits (63), Expect = 3.0
 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 6/93 (6%)

Query: 26   KMDILIKKLKQKFDDLMAEE---EAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEEN 82
            +++ L K LK + + ++ E    E V+++   L  +N  +      + K   E E L+ +
Sbjct: 1210 QLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLK---ETEVLQTD 1266

Query: 83   QKMLEEEILNLKTHMENSMVELSKLQEYKSELD 115
             K L+  + N K        E SKL+E   +LD
Sbjct: 1267 HKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLD 1299



 Score = 28.5 bits (62), Expect = 3.9
 Identities = 24/109 (22%), Positives = 52/109 (47%), Gaps = 7/109 (6%)

Query: 60  QVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMV---ELSKLQEYKSELDE 116
           Q ++++   +   +QE E++E   K L++E +NL +   ++ +   EL  L+E    +D+
Sbjct: 265 QELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDK 324

Query: 117 RAMQAVEKLKEIHLQMELDCVEQIIRETKR-TVAVLDTCCHLLSSLEST 164
              +     + +H   +++  +  + E K     +L+T   L   LE T
Sbjct: 325 LESEVSRYKERLH---DIEFYKARVEELKEDNQVLLETKTMLEDQLEGT 370



 Score = 28.1 bits (61), Expect = 5.0
 Identities = 25/114 (21%), Positives = 51/114 (44%), Gaps = 5/114 (4%)

Query: 18   EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
            ++LKT +   + L  K +Q  + ++     +S +     +++Q   +ELL   KV+    
Sbjct: 994  QELKTVKKNYEAL--KQRQDEERMVQSSPPISGEDNKWERESQETTRELL---KVKDRLI 1048

Query: 78   KLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQ 131
            ++E N   L+ E   LKT ++    + + LQ     L  + +   E+   +  Q
Sbjct: 1049 EVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQ 1102


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 48.1 bits (113), Expect = 5e-06
 Identities = 37/132 (28%), Positives = 60/132 (45%), Gaps = 17/132 (12%)

Query: 32   KKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQE----LLSMKKVQQECEKLEENQKMLE 87
            KKL Q+  D     EAV++KC +L K  Q +Q E    ++ +++    C  L++ Q+  +
Sbjct: 1395 KKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFD 1454

Query: 88   EEILNLKTHMENSMVELSKLQEYKSELD----------ERAMQAVEKLK--EIHLQMEL- 134
            + +   K   E +  EL   Q+    L           E ++  +E LK    +LQ E+ 
Sbjct: 1455 KILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEIS 1514

Query: 135  DCVEQIIRETKR 146
            D  EQI    KR
Sbjct: 1515 DLTEQIAEGGKR 1526



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 36/144 (25%), Positives = 71/144 (49%), Gaps = 18/144 (12%)

Query: 16   CHEDLKTDQLKMDILIKKLKQKFDD-------LMAEEEAVSSKCVNLSKDNQVIQQELLS 68
            C + +KT +++++  IK++ ++ +D       L A++  +  +C  L KD   ++   L+
Sbjct: 909  CDQLIKT-KIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE---LT 964

Query: 69   MKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQE-YKSELD-----ERAMQAV 122
            + KV++E    E   K L EE+  L   +     E   LQE ++  LD     E  +  +
Sbjct: 965  LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1024

Query: 123  EKLKEIHLQMELDCVEQIIRETKR 146
             K K I L+ ++D +E  + + K+
Sbjct: 1025 TKAK-IKLEQQVDDLEGSLEQEKK 1047



 Score = 37.7 bits (86), Expect = 0.006
 Identities = 29/119 (24%), Positives = 60/119 (50%), Gaps = 13/119 (10%)

Query: 18   EDLKTDQLKMDILIK---KLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQ 74
            +DL+ ++ K++ L K   KL+Q+ DDL    E      ++L +  + ++ +L   K  Q+
Sbjct: 1012 DDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDL---KLAQE 1068

Query: 75   ECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQME 133
                +E +++ L+E++       +    E+S LQ    +     MQ  +K+KE+  ++E
Sbjct: 1069 STMDIENDKQQLDEKL-------KKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIE 1120



 Score = 33.9 bits (76), Expect = 0.092
 Identities = 13/49 (26%), Positives = 31/49 (63%)

Query: 87  EEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQMELD 135
           E+E+ N+K   E +  EL+K +  + EL+E+ +  +++  ++ LQ++ +
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898



 Score = 30.8 bits (68), Expect = 0.78
 Identities = 36/166 (21%), Positives = 70/166 (42%), Gaps = 31/166 (18%)

Query: 19   DLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKK------- 71
            DL+   L+ +     L++K  D +AE   +  +  NL +  Q +++E   MK        
Sbjct: 1181 DLEEATLQHEATAATLRKKHADSVAE---LGEQIDNLQRVKQKLEKEKSEMKMEIDDLAS 1237

Query: 72   ----VQQECEKLEENQKMLEEEILNLKTHMENSM-------VELSKLQ----EYKSELDE 116
                V +    LE+  + LE+++  +KT  E           + ++LQ    EY  +LDE
Sbjct: 1238 NMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDE 1297

Query: 117  R--AMQAVEKLKEIHLQMELDCVEQIIRETKRTVAVLDTCCHLLSS 160
            +   +  + + K+   Q     +E++ R+ +  +       H L S
Sbjct: 1298 KDTLVSQLSRGKQAFTQQ----IEELKRQLEEEIKAKSALAHALQS 1339



 Score = 30.8 bits (68), Expect = 0.78
 Identities = 30/132 (22%), Positives = 60/132 (45%), Gaps = 25/132 (18%)

Query: 26   KMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKM 85
            K++  I +++ + +D++ E      K      D  ++ +EL   KK Q     LE  +K 
Sbjct: 1733 KLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEEL---KKEQDTSAHLERMKKN 1789

Query: 86   LEEEILNLKTHMENS--------MVELSKLQEYKSELD-------ERAMQAVE------- 123
            LE+ + +L+  ++ +          ++ KL+    EL+       +R ++AV+       
Sbjct: 1790 LEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHER 1849

Query: 124  KLKEIHLQMELD 135
            K+KE+  Q E D
Sbjct: 1850 KVKELTYQTEED 1861



 Score = 30.0 bits (66), Expect = 1.3
 Identities = 26/112 (23%), Positives = 55/112 (49%), Gaps = 14/112 (12%)

Query: 63  QQELLSMK----KVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERA 118
           ++E+ +MK    K ++E  K E  +K LEE+++ L     +  +++    +  ++ +ER 
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERC 909

Query: 119 MQAVE-------KLKEIHLQMELDCVEQIIRE-TKRTVAVLDTCCHLLSSLE 162
            Q ++       K+KE+  + E +  E+I  E T +   + D C  L   ++
Sbjct: 910 DQLIKTKIQLEAKIKEVTERAEDE--EEINAELTAKKRKLEDECSELKKDID 959



 Score = 28.1 bits (61), Expect = 5.0
 Identities = 21/82 (25%), Positives = 42/82 (51%), Gaps = 4/82 (4%)

Query: 34   LKQKFDDLMAEEEAVSSKCVNLSKDN-QVIQQELLSMKKVQQECEKLEENQKMLEEEILN 92
            L++++++   E+EA +     +SK N +V Q          Q  E+LEE +K L + + +
Sbjct: 1347 LREQYEE---EQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQD 1403

Query: 93   LKTHMENSMVELSKLQEYKSEL 114
             + H+E    + + L++ K  L
Sbjct: 1404 AEEHVEAVNAKCASLEKTKQRL 1425



 Score = 27.3 bits (59), Expect = 8.6
 Identities = 20/103 (19%), Positives = 52/103 (50%), Gaps = 4/103 (3%)

Query: 26   KMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQV-IQQELLSMKKVQQECEKLEENQK 84
            K +   +K+++  ++   + EA ++       D+   + +++ ++++V+Q+ EK +   K
Sbjct: 1170 KREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMK 1229

Query: 85   MLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKE 127
            M   EI +L ++ME        L++    L+++  +   K +E
Sbjct: 1230 M---EIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEE 1269


>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
            sapiens]
          Length = 1939

 Score = 48.1 bits (113), Expect = 5e-06
 Identities = 32/118 (27%), Positives = 53/118 (44%), Gaps = 9/118 (7%)

Query: 32   KKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQE----LLSMKKVQQECEKLEENQKMLE 87
            KKL Q+  D     EAV+SKC +L K  Q +Q E    ++ +++    C  L++ Q+  +
Sbjct: 1395 KKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFD 1454

Query: 88   EEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQMELDCVEQIIRETK 145
            + +   K   E +  EL   Q+    L     +     +E      LD +E + RE K
Sbjct: 1455 KVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEE-----SLDHLETLKRENK 1507



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 28/133 (21%), Positives = 66/133 (49%), Gaps = 6/133 (4%)

Query: 18   EDLKTDQLKMDILIK---KLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQ 74
            +DL+ ++ K++ L K   KL+Q+ DDL    E     C++L +  + ++ +L   K  Q+
Sbjct: 1012 DDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDL---KLAQE 1068

Query: 75   ECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQMEL 134
                 E +++ L E++   +  M N   ++   Q    +L ++  +   +++E+  ++E 
Sbjct: 1069 STMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEA 1128

Query: 135  DCVEQIIRETKRT 147
            +   +   E +R+
Sbjct: 1129 ERASRAKAEKQRS 1141



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 29/118 (24%), Positives = 54/118 (45%), Gaps = 11/118 (9%)

Query: 20   LKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQEC--- 76
            L   Q   D ++ + KQK+++  AE EA         K+++ +  EL  +K   +E    
Sbjct: 1446 LDKKQRNFDKVLAEWKQKYEETQAELEASQ-------KESRSLSTELFKVKNAYEESLDH 1498

Query: 77   -EKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQME 133
             E L+   K L++EI +L   +      + +L++ K +LD    +    L+E    +E
Sbjct: 1499 LETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLE 1556



 Score = 37.7 bits (86), Expect = 0.006
 Identities = 35/144 (24%), Positives = 71/144 (49%), Gaps = 18/144 (12%)

Query: 16   CHEDLKTDQLKMDILIKKLKQKFDD-------LMAEEEAVSSKCVNLSKDNQVIQQELLS 68
            C + +KT +++++  IK++ ++ +D       L A++  +  +C  L KD   ++   L+
Sbjct: 909  CDQLIKT-KIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE---LT 964

Query: 69   MKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQE-YKSELDERAMQ-----AV 122
            + KV++E    E   K L EE+  L   +     E   LQE ++  LD+  M+      +
Sbjct: 965  LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTL 1024

Query: 123  EKLKEIHLQMELDCVEQIIRETKR 146
             K K   L+ ++D +E  + + K+
Sbjct: 1025 TKAK-TKLEQQVDDLEGSLEQEKK 1047



 Score = 33.9 bits (76), Expect = 0.092
 Identities = 13/49 (26%), Positives = 31/49 (63%)

Query: 87  EEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQMELD 135
           E+E+ N+K   E +  EL+K +  + EL+E+ +  +++  ++ LQ++ +
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898



 Score = 33.1 bits (74), Expect = 0.16
 Identities = 26/113 (23%), Positives = 51/113 (45%), Gaps = 14/113 (12%)

Query: 35   KQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEI---- 90
            +Q  DDL  EE+ V++     +K  Q +     S+++ ++ C  LE  ++ LE ++    
Sbjct: 1008 QQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQ 1067

Query: 91   ----------LNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQME 133
                        L   ++    E+S LQ    +    A+Q  +K+KE+  ++E
Sbjct: 1068 ESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIE 1120



 Score = 30.0 bits (66), Expect = 1.3
 Identities = 26/112 (23%), Positives = 55/112 (49%), Gaps = 14/112 (12%)

Query: 63  QQELLSMK----KVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERA 118
           ++E+ +MK    K ++E  K E  +K LEE+++ L     +  +++    +  ++ +ER 
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERC 909

Query: 119 MQAVE-------KLKEIHLQMELDCVEQIIRE-TKRTVAVLDTCCHLLSSLE 162
            Q ++       K+KE+  + E +  E+I  E T +   + D C  L   ++
Sbjct: 910 DQLIKTKIQLEAKIKEVTERAEDE--EEINAELTAKKRKLEDECSELKKDID 959



 Score = 30.0 bits (66), Expect = 1.3
 Identities = 35/159 (22%), Positives = 67/159 (42%), Gaps = 17/159 (10%)

Query: 19   DLKTDQLKMDILIKKLKQKFDDLMAE--EEAVSSKCVN--LSKDNQVIQQELLSMKKVQQ 74
            DL+   L+ +     L++K  D +AE  E+  S + V   L K+   ++ E+  +    +
Sbjct: 1181 DLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNME 1240

Query: 75   ECEKLEEN-QKM---LEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHL 130
               K + N +KM   LE+++  +KT  E     +++L   K+ L   + +   +L E   
Sbjct: 1241 TVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDA 1300

Query: 131  ---------QMELDCVEQIIRETKRTVAVLDTCCHLLSS 160
                     Q     +E++ R+ +       T  H L S
Sbjct: 1301 MVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQS 1339



 Score = 30.0 bits (66), Expect = 1.3
 Identities = 21/112 (18%), Positives = 54/112 (48%), Gaps = 17/112 (15%)

Query: 30   LIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEE 89
            ++K  +   DD +  ++ +  +   + +   ++Q E+   ++++   E+ E  +KM E+E
Sbjct: 1653 ILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEV---EELRASLERTERGRKMAEQE 1709

Query: 90   ILNLK-----THMENSMV---------ELSKLQEYKSELDERAMQAVEKLKE 127
            +L+        H +N+ +         ++S++Q    ++ + A  A EK K+
Sbjct: 1710 LLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKK 1761



 Score = 28.1 bits (61), Expect = 5.0
 Identities = 21/82 (25%), Positives = 42/82 (51%), Gaps = 4/82 (4%)

Query: 34   LKQKFDDLMAEEEAVSSKCVNLSKDN-QVIQQELLSMKKVQQECEKLEENQKMLEEEILN 92
            L++++++   E+EA +     +SK N +V Q          Q  E+LEE +K L + + +
Sbjct: 1347 LREQYEE---EQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQD 1403

Query: 93   LKTHMENSMVELSKLQEYKSEL 114
             + H+E    + + L++ K  L
Sbjct: 1404 AEEHVEAVNSKCASLEKTKQRL 1425


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 47.4 bits (111), Expect = 8e-06
 Identities = 42/146 (28%), Positives = 72/146 (49%), Gaps = 20/146 (13%)

Query: 35  KQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMK-----KVQQECEKLEENQKMLEEE 89
           +QK+  ++ E E ++ + VNLSK+ Q     L ++K     K Q+  EK  E Q+ L  E
Sbjct: 830 EQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERL-NE 888

Query: 90  ILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEI------------HLQMELDCV 137
           +  LK  +EN    L  ++  K+ + E+  Q +E++K +             LQ+E D +
Sbjct: 889 MEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQL 948

Query: 138 EQIIRETKRTVAVLDTCCHLLSSLES 163
           +  I +T      +DT   L ++LES
Sbjct: 949 KSDIHDTVN--MNIDTQEQLRNALES 972



 Score = 38.9 bits (89), Expect = 0.003
 Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 16/128 (12%)

Query: 33   KLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILN 92
            KL++K  +L A E  +    + L KD    Q+++  M++++++ +        LE E LN
Sbjct: 1817 KLQEKIQELKANEHQL----ITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLN 1872

Query: 93   L--KTH-----MENSMVELSKLQEYKSELDERAMQAVEKLKE-----IHLQMELDCVEQI 140
            L  K H     M++ M E   L+  +  L     Q  E L+E     + +Q EL     +
Sbjct: 1873 LAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARML 1932

Query: 141  IRETKRTV 148
             +E K TV
Sbjct: 1933 SKEHKETV 1940



 Score = 35.4 bits (80), Expect = 0.032
 Identities = 32/136 (23%), Positives = 66/136 (48%), Gaps = 8/136 (5%)

Query: 15   VCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQEL----LSMK 70
            + H  LK  Q  +D L   + +K +++   ++ +      L   +  IQ+EL    + +K
Sbjct: 1725 IVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLK 1784

Query: 71   KVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIH- 129
            + Q+  +KL        +++ N++  +ENS    +KLQE   EL     Q +   K+++ 
Sbjct: 1785 EQQETIDKLRGIVSEKTDKLSNMQKDLENSN---AKLQEKIQELKANEHQLITLKKDVNE 1841

Query: 130  LQMELDCVEQIIRETK 145
             Q ++  +EQ+ ++ K
Sbjct: 1842 TQKKVSEMEQLKKQIK 1857



 Score = 34.7 bits (78), Expect = 0.054
 Identities = 29/140 (20%), Positives = 64/140 (45%), Gaps = 23/140 (16%)

Query: 2    TINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQV 61
            TIN L V  +E      ++ T Q +++ +  KL+ K  ++  +EE  + K ++       
Sbjct: 1492 TINELRVNLSEK---ETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQIS------E 1542

Query: 62   IQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELS--------------KL 107
            +Q+++  +K+ ++  +  +   + +E ++L L   ++ S  E+                L
Sbjct: 1543 VQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEAL 1602

Query: 108  QEYKSELDERAMQAVEKLKE 127
            Q  + +L E   + V K+KE
Sbjct: 1603 QIERDQLKENTKEIVAKMKE 1622



 Score = 33.9 bits (76), Expect = 0.092
 Identities = 38/125 (30%), Positives = 57/125 (45%), Gaps = 19/125 (15%)

Query: 33   KLKQKFDDLMAEEEAVSSKCVNLSKDNQV---IQQELLSMKKVQQECEKLEENQKMLEEE 89
            +L +  D L   EE +  K   L +  Q    +Q+E+  M+K   E E L+   K  E  
Sbjct: 1114 ELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKE-- 1171

Query: 90   ILNLKTHMENSMVELSK-----LQEYKSELDERAMQAVEKLKEIH--LQMELDCVEQIIR 142
             L L+ HME   +EL++      +E KS   ER +     LKE+    + E D +   IR
Sbjct: 1172 -LTLE-HMETERLELAQKLNENYEEVKSITKERKV-----LKELQKSFETERDHLRGYIR 1224

Query: 143  ETKRT 147
            E + T
Sbjct: 1225 EIEAT 1229



 Score = 33.5 bits (75), Expect = 0.12
 Identities = 27/107 (25%), Positives = 57/107 (53%), Gaps = 6/107 (5%)

Query: 18   EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMK--KVQQE 75
            E LKTD LK +I +    Q+   L+ +E     + V   K++ + ++  LS    ++ + 
Sbjct: 1067 EQLKTD-LKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEV 1125

Query: 76   CEKLEENQKMLEE---EILNLKTHMENSMVELSKLQEYKSELDERAM 119
             EKL+E  + L+E   ++LN++  M     ++++++  K+EL  + +
Sbjct: 1126 EEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKEL 1172



 Score = 31.2 bits (69), Expect = 0.60
 Identities = 26/133 (19%), Positives = 65/133 (48%), Gaps = 12/133 (9%)

Query: 33   KLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILN 92
            +L+Q  + ++AE+E + +           +++ +    + Q+E   L +  K  +E +  
Sbjct: 1054 ELQQMLESVIAEKEQLKTD----------LKENIEMTIENQEELRLLGDELKKQQEIVAQ 1103

Query: 93   LKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQMELDCVEQIIRETKRTVAVLD 152
             K H      ELS+  +  +E++E+  +  ++L+E   Q +L  V++ + E ++ +  ++
Sbjct: 1104 EKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQE--KQQQLLNVQEEMSEMQKKINEIE 1161

Query: 153  TCCHLLSSLESTV 165
               + L + E T+
Sbjct: 1162 NLKNELKNKELTL 1174



 Score = 28.9 bits (63), Expect = 3.0
 Identities = 28/113 (24%), Positives = 56/113 (49%), Gaps = 7/113 (6%)

Query: 18   EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
            +D+   Q K+  + ++LK++  D       +  + +NL+   Q + + L  MK V +E +
Sbjct: 1837 KDVNETQKKVSEM-EQLKKQIKDQSLTLSKLEIENLNLA---QKLHENLEEMKSVMKERD 1892

Query: 78   KLEENQKMLEEEILNLKTHMENSMV-ELSKLQEYKSE--LDERAMQAVEKLKE 127
             L   ++ L+ E   LK  ++ +   +L   QE K+   L +   + V+KL+E
Sbjct: 1893 NLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLRE 1945



 Score = 27.7 bits (60), Expect = 6.6
 Identities = 26/111 (23%), Positives = 51/111 (45%), Gaps = 23/111 (20%)

Query: 57   KDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDE 116
            KDN++I+Q+    +K+    ++  E Q+MLE  I              ++ ++ K++L E
Sbjct: 1034 KDNEIIEQQ----RKIFSLIQEKNELQQMLESVI--------------AEKEQLKTDLKE 1075

Query: 117  RAMQAVEKLKEIH-LQMELDCVEQIIRETK----RTVAVLDTCCHLLSSLE 162
                 +E  +E+  L  EL   ++I+ + K    +    L   C  L+ +E
Sbjct: 1076 NIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVE 1126


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 47.4 bits (111), Expect = 8e-06
 Identities = 32/118 (27%), Positives = 56/118 (47%), Gaps = 9/118 (7%)

Query: 32   KKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQE----LLSMKKVQQECEKLEENQKMLE 87
            KKL Q+  +     EAV++KC +L K  Q +Q E    +L +++    C  L++ Q+  +
Sbjct: 1394 KKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFD 1453

Query: 88   EEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQMELDCVEQIIRETK 145
            + +   K   E +  EL   Q+    L         K+K ++ +  LD +E + RE K
Sbjct: 1454 KVLSEWKQKYEETQAELEASQKESRSLSTELF----KVKNVY-EESLDQLETLRRENK 1506



 Score = 37.4 bits (85), Expect = 0.008
 Identities = 31/121 (25%), Positives = 66/121 (54%), Gaps = 17/121 (14%)

Query: 18   EDLKTDQLKMDILIK---KLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQ 74
            +DL+ ++ K++IL K   KL+Q+ DDL    E      ++L +  + ++ +L   K  Q+
Sbjct: 1011 DDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL---KLAQE 1067

Query: 75   ECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAM--QAVEKLKEIHLQM 132
                +E +++ L+E++   +  + N    +SK++      DE+A+  Q  +K+KE+  ++
Sbjct: 1068 STMDMENDKQQLDEKLEKKEFEISNL---ISKIE------DEQAVEIQLQKKIKELQARI 1118

Query: 133  E 133
            E
Sbjct: 1119 E 1119



 Score = 36.2 bits (82), Expect = 0.019
 Identities = 25/116 (21%), Positives = 58/116 (50%), Gaps = 3/116 (2%)

Query: 18   EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
            ++L+  + K++    +LK + DDL +  EA+S    NL K  + ++ ++  +K  ++E +
Sbjct: 1211 DNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQ 1270

Query: 78   KLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQME 133
            +L  +   L  +   L+T       +L +     S+L      + ++++E+  Q+E
Sbjct: 1271 RLIND---LTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLE 1323



 Score = 35.8 bits (81), Expect = 0.024
 Identities = 34/143 (23%), Positives = 69/143 (48%), Gaps = 19/143 (13%)

Query: 18   EDLKTDQLKMDILIKKLKQKFDD-------LMAEEEAVSSKCVNLSKDNQVIQQELLSMK 70
            E L  ++++++  IK++ ++ ++       L A++  +  +C  L KD   ++   L++ 
Sbjct: 909  EQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLE---LTLA 965

Query: 71   KVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQE-YKSELDERAMQAVEKLKEI- 128
            KV++E    E   K L EE+  L   +     E   LQE ++  LD+  +QA E    I 
Sbjct: 966  KVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDD--LQAEEDKVNIL 1023

Query: 129  -----HLQMELDCVEQIIRETKR 146
                  L+ ++D +E  + + K+
Sbjct: 1024 TKAKTKLEQQVDDLEGSLEQEKK 1046



 Score = 34.7 bits (78), Expect = 0.054
 Identities = 35/151 (23%), Positives = 67/151 (44%), Gaps = 27/151 (17%)

Query: 19   DLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMK-------- 70
            DL+   L+ + ++  L++K  D MAE   +  +  NL +  Q +++E   +K        
Sbjct: 1180 DLEEATLQHEAMVAALRKKHADSMAE---LGEQIDNLQRVKQKLEKEKSELKMETDDLSS 1236

Query: 71   ---KVQQECEKLEENQKMLEEEILNLKTHMENSM-------VELSKLQ----EYKSELDE 116
                + +    LE+  + LE+++  LKT  E           + ++LQ    EY  +LDE
Sbjct: 1237 NAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDE 1296

Query: 117  R--AMQAVEKLKEIHLQMELDCVEQIIRETK 145
            +   +  + + K+   Q   +   Q+  ETK
Sbjct: 1297 KDALVSQLSRSKQASTQQIEELKHQLEEETK 1327



 Score = 29.6 bits (65), Expect = 1.7
 Identities = 26/112 (23%), Positives = 54/112 (48%), Gaps = 14/112 (12%)

Query: 63  QQELLSMK----KVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERA 118
           ++E+ +MK    K + E  K E  +K LEE+++ L     +  +++    +  ++ +ER 
Sbjct: 849 EKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERC 908

Query: 119 MQAVE-------KLKEIHLQMELDCVEQIIRE-TKRTVAVLDTCCHLLSSLE 162
            Q ++       K+KE+  + E +  E+I  E T +   + D C  L   ++
Sbjct: 909 EQLIKNKIQLEAKIKEVTERAEEE--EEINAELTAKKRKLEDECSELKKDID 958



 Score = 28.1 bits (61), Expect = 5.0
 Identities = 30/153 (19%), Positives = 68/153 (44%), Gaps = 19/153 (12%)

Query: 26   KMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKM 85
            K++  + +L+ + ++++ E      K      D  ++ +EL   KK Q     LE  +K 
Sbjct: 1732 KLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEEL---KKEQDTSAHLERMKKN 1788

Query: 86   LEEEILNLKTHMENS--------MVELSKLQEYKSELD-------ERAMQAVEKLKEIHL 130
            LE+ + +L+  ++ +          ++ KL+    EL+       +R  +AV+ L++ H 
Sbjct: 1789 LEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRK-HE 1847

Query: 131  QMELDCVEQIIRETKRTVAVLDTCCHLLSSLES 163
            +   +   Q   + K  + + D    L + ++S
Sbjct: 1848 RRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKS 1880


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 36/119 (30%), Positives = 61/119 (51%), Gaps = 11/119 (9%)

Query: 32   KKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQE----LLSMKKVQQECEKLEENQKMLE 87
            KKL Q+  D   + EAV++KC +L K  Q +Q E    ++ +++       L++ Q+  +
Sbjct: 1392 KKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFD 1451

Query: 88   EEILNLKTHMENSMVEL-SKLQEYKSELDERAMQAVEKLKEIHLQMELDCVEQIIRETK 145
            + +   KT  E S  EL + L+E +S   E     + KLK  + +  LD +E + RE K
Sbjct: 1452 KVLAEWKTKCEESQAELEASLKESRSLSTE-----LFKLKNAY-EEALDQLETVKRENK 1504



 Score = 38.9 bits (89), Expect = 0.003
 Identities = 38/129 (29%), Positives = 64/129 (49%), Gaps = 16/129 (12%)

Query: 35   KQKFDDLMAEEEAVSSKCVNLSK-DNQV--IQQELLSMKKVQQECE----KLEENQKMLE 87
            +Q  DDL AEE+ V+S     SK + QV  ++  L   KK++ + E    KLE + K+ +
Sbjct: 1005 QQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQ 1064

Query: 88   EEILNLKT-------HMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQMELDCVEQI 140
            E IL+L+         ++    E  +LQ    +     +Q  +K+KE  LQ  ++ +E+ 
Sbjct: 1065 ESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKE--LQARIEELEEE 1122

Query: 141  IRETKRTVA 149
            I   + T A
Sbjct: 1123 IEAERATRA 1131



 Score = 34.3 bits (77), Expect = 0.070
 Identities = 29/118 (24%), Positives = 56/118 (47%), Gaps = 18/118 (15%)

Query: 16   CHEDLKTDQLKMDILIKKLKQKFDD-------LMAEEEAVSSKCVNLSKDNQVIQQELLS 68
            C + +K  + +++  IK++ ++ +D       L A++  +  +C  L KD   ++   L+
Sbjct: 906  CDQLIKA-KFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE---LT 961

Query: 69   MKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLK 126
            + KV++E    E   K L EE+  L          ++KL   K  L E   QA++ L+
Sbjct: 962  LAKVEKEKHATENKVKNLTEELSGLDE-------TIAKLTREKKALQEAHQQALDDLQ 1012



 Score = 30.8 bits (68), Expect = 0.78
 Identities = 12/49 (24%), Positives = 30/49 (61%)

Query: 87  EEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQMELD 135
           E+E+  +K   + +  EL+K +  + EL+E+ +  V++  ++ LQ++ +
Sbjct: 847 EKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAE 895



 Score = 29.3 bits (64), Expect = 2.3
 Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 14/112 (12%)

Query: 63  QQELLSMK----KVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERA 118
           ++E+ +MK    K + E  K E  +K LEE+++ L     +  +++    E   + +ER 
Sbjct: 847 EKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERC 906

Query: 119 MQAVE-------KLKEIHLQMELDCVEQIIRE-TKRTVAVLDTCCHLLSSLE 162
            Q ++       K+KE+  + E +  E+I  E T +   + D C  L   ++
Sbjct: 907 DQLIKAKFQLEAKIKEVTERAEDE--EEINAELTAKKRKLEDECSELKKDID 956



 Score = 28.1 bits (61), Expect = 5.0
 Identities = 24/110 (21%), Positives = 55/110 (50%), Gaps = 20/110 (18%)

Query: 19   DLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEK 78
            DL+   L+ + ++  L++K  D +AE                 + +++ ++++V+Q+ EK
Sbjct: 1178 DLEEATLQHEAMVAALRKKHADSVAE-----------------LGEQIDNLQRVKQKLEK 1220

Query: 79   LEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEI 128
             +   K+   EI +L + ME+     + L++    L+++  +A  K +EI
Sbjct: 1221 EKSEFKL---EIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEI 1267


>gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens]
          Length = 446

 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 25/96 (26%), Positives = 52/96 (54%), Gaps = 3/96 (3%)

Query: 31  IKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEI 90
           +++++Q   +L  E + +   C++L K N  +Q EL   +K Q+E E L+   K LE ++
Sbjct: 142 VEEIEQHNKELCKENQELKDSCISLQKQNSDMQAEL---QKKQEELETLQSINKKLELKV 198

Query: 91  LNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLK 126
              K + E  +++L +  +  S  +E+    V++L+
Sbjct: 199 KEQKDYWETELLQLKEQNQKMSSENEKMGIRVDQLQ 234



 Score = 30.8 bits (68), Expect = 0.78
 Identities = 21/87 (24%), Positives = 46/87 (52%), Gaps = 9/87 (10%)

Query: 14  FVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSK---DNQVIQQELLSMK 70
           F+   + + DQ K++  ++++KQ     M +++ +  +  +LSK   +N++I   L    
Sbjct: 269 FLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICNAL---- 324

Query: 71  KVQQECEKLEENQKMLEEEILNLKTHM 97
             Q++ E+LE    +L+ E   L ++M
Sbjct: 325 --QRQKERLEGENDLLKRENSRLLSYM 349



 Score = 28.9 bits (63), Expect = 3.0
 Identities = 27/132 (20%), Positives = 63/132 (47%), Gaps = 10/132 (7%)

Query: 20  LKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKL 79
           ++ DQL+  +  ++  ++ + L+  ++  + +   L K+N  +   L   +K Q++ E+ 
Sbjct: 228 IRVDQLQAQLSTQE--KEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQT 285

Query: 80  EENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQMELDCVEQ 139
            E  K  E   +  +  + +   +LSK    +   +E    A+++ KE  L+ E D ++ 
Sbjct: 286 VEQMKQNETTAMKKQQELMDENFDLSK----RLSENEIICNALQRQKE-RLEGENDLLK- 339

Query: 140 IIRETKRTVAVL 151
             RE  R ++ +
Sbjct: 340 --RENSRLLSYM 349


>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
          Length = 1684

 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 30/105 (28%), Positives = 58/105 (55%), Gaps = 4/105 (3%)

Query: 30  LIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELL-SMKKVQQECEKLEENQKMLEE 88
           +IK L ++ D L+ E+     +C++L K+N  ++QE+  S+ K+    ++LE++     +
Sbjct: 70  IIKALTERLDALLLEKAETEQQCLSLKKENIKMKQEVEDSVTKMGDAHKELEQSHINYVK 129

Query: 89  EILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQME 133
           EI NLK  +   M   SK  E K+ L ++  +A+    E+  Q++
Sbjct: 130 EIENLKNEL---MAVRSKYSEDKANLQKQLEEAMNTQLELSEQLK 171



 Score = 35.0 bits (79), Expect = 0.041
 Identities = 25/132 (18%), Positives = 60/132 (45%), Gaps = 6/132 (4%)

Query: 17  HEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQEC 76
           H++L+   +     +K+++   ++LMA     S    NL K  +      L + +  +  
Sbjct: 117 HKELEQSHINY---VKEIENLKNELMAVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQ 173

Query: 77  EKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEI---HLQME 133
              E+N K L+EEI  ++   E  ++ L K  +  ++  +  +  ++ + E    H Q  
Sbjct: 174 NNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKN 233

Query: 134 LDCVEQIIRETK 145
           ++ +++ + + K
Sbjct: 234 INSLQEELLQLK 245



 Score = 31.2 bits (69), Expect = 0.60
 Identities = 25/123 (20%), Positives = 52/123 (42%), Gaps = 4/123 (3%)

Query: 26   KMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKM 85
            ++ + ++K K++    M E E V       +  N  I      MK++ Q+        + 
Sbjct: 1126 ELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNNKIED 1185

Query: 86   LEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQMELDCVEQIIRETK 145
            LE+EI   K   E    E++ LQ    + +E+      K+K++ ++ + +  +    ET 
Sbjct: 1186 LEQEIKIQKQKQETLQEEITSLQSSVQQYEEKN----TKIKQLLVKTKKELADSKQAETD 1241

Query: 146  RTV 148
              +
Sbjct: 1242 HLI 1244


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 37/132 (28%), Positives = 59/132 (44%), Gaps = 17/132 (12%)

Query: 32   KKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQE----LLSMKKVQQECEKLEENQKMLE 87
            KKL Q+        EAV++KC +L K  Q +Q E    +L +++    C  L++ Q+  +
Sbjct: 1397 KKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFD 1456

Query: 88   EEILNLKTHMENSMVELSKLQEYKSELD----------ERAMQAVEKLK--EIHLQMEL- 134
            + +   K   E +  EL   Q+    L           E ++  +E LK    +LQ E+ 
Sbjct: 1457 KILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEIS 1516

Query: 135  DCVEQIIRETKR 146
            D  EQI    KR
Sbjct: 1517 DLTEQIAEGGKR 1528



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 37/145 (25%), Positives = 76/145 (52%), Gaps = 19/145 (13%)

Query: 18   EDLKTDQLKMDILIK---KLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELL----SMK 70
            +DL+ ++ K++ L K   KL+Q+ DDL    E      ++L +  + ++ +L     S+ 
Sbjct: 1014 DDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIM 1073

Query: 71   KVQQECEKLEENQKMLEEEILNLKTHMENSM---VELSK--------LQEYKSELD-ERA 118
             ++ E ++L+E  K  E EI NL++ +E+     ++L K        ++E + E++ ERA
Sbjct: 1074 DIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERA 1133

Query: 119  MQAVEKLKEIHLQMELDCVEQIIRE 143
             +A  + +   L  EL+ + + + E
Sbjct: 1134 SRAKAEKQRSDLSRELEEISERLEE 1158



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 36/144 (25%), Positives = 71/144 (49%), Gaps = 18/144 (12%)

Query: 16   CHEDLKTDQLKMDILIKKLKQKFDD-------LMAEEEAVSSKCVNLSKDNQVIQQELLS 68
            C + +KT +++++  IK++ ++ +D       L A++  +  +C  L KD   ++   L+
Sbjct: 911  CDQLIKT-KIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE---LT 966

Query: 69   MKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQE-YKSELD-----ERAMQAV 122
            + KV++E    E   K L EE+  L   +     E   LQE ++  LD     E  +  +
Sbjct: 967  LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1026

Query: 123  EKLKEIHLQMELDCVEQIIRETKR 146
             K K I L+ ++D +E  + + K+
Sbjct: 1027 TKAK-IKLEQQVDDLEGSLEQEKK 1049



 Score = 38.1 bits (87), Expect = 0.005
 Identities = 28/113 (24%), Positives = 56/113 (49%), Gaps = 14/113 (12%)

Query: 35   KQKFDDLMAEEEAVSSKC---VNLSKDNQVIQQELLSMKKVQQECE----KLEENQKMLE 87
            +Q  DDL AEE+ V++     + L +    ++  L   KK++ + E    KLE + K+ +
Sbjct: 1010 QQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1069

Query: 88   EEILNLKTH-------MENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQME 133
            E I++++         ++    E+S LQ    +     +Q  +K+KE+  ++E
Sbjct: 1070 ESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIE 1122



 Score = 30.4 bits (67), Expect = 1.0
 Identities = 27/112 (24%), Positives = 55/112 (49%), Gaps = 14/112 (12%)

Query: 63  QQELLSMK----KVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERA 118
           ++E+ +MK    K++ E  K E  +K LEE+++ L     +  +++    E  ++ +ER 
Sbjct: 852 EKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERC 911

Query: 119 MQAVE-------KLKEIHLQMELDCVEQIIRE-TKRTVAVLDTCCHLLSSLE 162
            Q ++       K+KE+  + E +  E+I  E T +   + D C  L   ++
Sbjct: 912 DQLIKTKIQLEAKIKEVTERAEDE--EEINAELTAKKRKLEDECSELKKDID 961


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 37/132 (28%), Positives = 59/132 (44%), Gaps = 17/132 (12%)

Query: 32   KKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQE----LLSMKKVQQECEKLEENQKMLE 87
            KKL Q+        EAV++KC +L K  Q +Q E    +L +++    C  L++ Q+  +
Sbjct: 1397 KKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFD 1456

Query: 88   EEILNLKTHMENSMVELSKLQEYKSELD----------ERAMQAVEKLK--EIHLQMEL- 134
            + +   K   E +  EL   Q+    L           E ++  +E LK    +LQ E+ 
Sbjct: 1457 KILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEIS 1516

Query: 135  DCVEQIIRETKR 146
            D  EQI    KR
Sbjct: 1517 DLTEQIAEGGKR 1528



 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 37/145 (25%), Positives = 76/145 (52%), Gaps = 19/145 (13%)

Query: 18   EDLKTDQLKMDILIK---KLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELL----SMK 70
            +DL+ ++ K++ L K   KL+Q+ DDL    E      ++L +  + ++ +L     S+ 
Sbjct: 1014 DDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIM 1073

Query: 71   KVQQECEKLEENQKMLEEEILNLKTHMENSM---VELSK--------LQEYKSELD-ERA 118
             ++ E ++L+E  K  E EI NL++ +E+     ++L K        ++E + E++ ERA
Sbjct: 1074 DIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERA 1133

Query: 119  MQAVEKLKEIHLQMELDCVEQIIRE 143
             +A  + +   L  EL+ + + + E
Sbjct: 1134 SRAKAEKQRSDLSRELEEISERLEE 1158



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 36/144 (25%), Positives = 71/144 (49%), Gaps = 18/144 (12%)

Query: 16   CHEDLKTDQLKMDILIKKLKQKFDD-------LMAEEEAVSSKCVNLSKDNQVIQQELLS 68
            C + +KT +++++  IK++ ++ +D       L A++  +  +C  L KD   ++   L+
Sbjct: 911  CDQLIKT-KIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE---LT 966

Query: 69   MKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQE-YKSELD-----ERAMQAV 122
            + KV++E    E   K L EE+  L   +     E   LQE ++  LD     E  +  +
Sbjct: 967  LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1026

Query: 123  EKLKEIHLQMELDCVEQIIRETKR 146
             K K I L+ ++D +E  + + K+
Sbjct: 1027 TKAK-IKLEQQVDDLEGSLEQEKK 1049



 Score = 38.1 bits (87), Expect = 0.005
 Identities = 28/113 (24%), Positives = 56/113 (49%), Gaps = 14/113 (12%)

Query: 35   KQKFDDLMAEEEAVSSKC---VNLSKDNQVIQQELLSMKKVQQECE----KLEENQKMLE 87
            +Q  DDL AEE+ V++     + L +    ++  L   KK++ + E    KLE + K+ +
Sbjct: 1010 QQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1069

Query: 88   EEILNLKTH-------MENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQME 133
            E I++++         ++    E+S LQ    +     +Q  +K+KE+  ++E
Sbjct: 1070 ESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIE 1122



 Score = 30.4 bits (67), Expect = 1.0
 Identities = 27/112 (24%), Positives = 55/112 (49%), Gaps = 14/112 (12%)

Query: 63  QQELLSMK----KVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERA 118
           ++E+ +MK    K++ E  K E  +K LEE+++ L     +  +++    E  ++ +ER 
Sbjct: 852 EKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERC 911

Query: 119 MQAVE-------KLKEIHLQMELDCVEQIIRE-TKRTVAVLDTCCHLLSSLE 162
            Q ++       K+KE+  + E +  E+I  E T +   + D C  L   ++
Sbjct: 912 DQLIKTKIQLEAKIKEVTERAEDE--EEINAELTAKKRKLEDECSELKKDID 961


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.358 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,686,018
Number of Sequences: 37866
Number of extensions: 270733
Number of successful extensions: 5154
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 305
Number of HSP's successfully gapped in prelim test: 577
Number of HSP's that attempted gapping in prelim test: 2648
Number of HSP's gapped (non-prelim): 2612
length of query: 197
length of database: 18,247,518
effective HSP length: 97
effective length of query: 100
effective length of database: 14,574,516
effective search space: 1457451600
effective search space used: 1457451600
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.