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Search of human proteins with 169172639
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169172639 PREDICTED: similar to U5 snRNP-associated 102 kDa
protein [Homo sapiens]
(406 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169172639 PREDICTED: similar to U5 snRNP-associated 102 kDa p... 826 0.0
gi|40807485 PRP6 pre-mRNA processing factor 6 homolog [Homo sapi... 806 0.0
gi|124256489 crooked neck-like 1 protein [Homo sapiens] 61 2e-09
gi|70980549 programmed cell death 11 [Homo sapiens] 53 6e-07
gi|83415184 transmembrane and tetratricopeptide repeat containin... 48 2e-05
gi|55770906 XPA binding protein 2 [Homo sapiens] 47 4e-05
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 41 0.002
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 41 0.002
gi|156938331 PRP39 pre-mRNA processing factor 39 homolog [Homo s... 41 0.002
gi|7110679 tetratricopeptide repeat domain 33 [Homo sapiens] 39 0.006
gi|224809432 transmembrane and tetratricopeptide repeat containi... 39 0.008
gi|7661952 squamous cell carcinoma antigen recognized by T cells... 37 0.032
gi|118766328 transmembrane and tetratricopeptide repeat containi... 37 0.042
gi|118766330 transmembrane and tetratricopeptide repeat containi... 37 0.042
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] 35 0.093
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 35 0.093
gi|52630440 FK506-binding protein 8 [Homo sapiens] 35 0.12
gi|21735548 centrosomal protein 2 [Homo sapiens] 35 0.16
gi|49574529 hepatocellular carcinoma-associated antigen 66 [Homo... 35 0.16
gi|110225358 tetratricopeptide repeat domain 7A [Homo sapiens] 35 0.16
gi|45439327 periplakin [Homo sapiens] 34 0.21
gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens] 34 0.27
gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens] 34 0.27
gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens] 34 0.27
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 33 0.35
gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapi... 33 0.35
gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapi... 33 0.35
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 33 0.46
gi|7019491 DNA-directed DNA polymerase lambda [Homo sapiens] 33 0.60
gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2 ... 32 0.79
>gi|169172639 PREDICTED: similar to U5 snRNP-associated 102 kDa
protein [Homo sapiens]
Length = 406
Score = 826 bits (2133), Expect = 0.0
Identities = 406/406 (100%), Positives = 406/406 (100%)
Query: 1 MAEIKSWHEEDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEA 60
MAEIKSWHEEDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEA
Sbjct: 1 MAEIKSWHEEDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEA 60
Query: 61 LLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESEN 120
LLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESEN
Sbjct: 61 LLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESEN 120
Query: 121 DEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMK 180
DEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMK
Sbjct: 121 DEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMK 180
Query: 181 GQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPK 240
GQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPK
Sbjct: 181 GQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPK 240
Query: 241 NPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGILWSEAIFLEARPQRRTKSVDALK 300
NPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGILWSEAIFLEARPQRRTKSVDALK
Sbjct: 241 NPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGILWSEAIFLEARPQRRTKSVDALK 300
Query: 301 KCEHDPHVLLAVAKLFWSQRKITKAREWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQE 360
KCEHDPHVLLAVAKLFWSQRKITKAREWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQE
Sbjct: 301 KCEHDPHVLLAVAKLFWSQRKITKAREWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQE 360
Query: 361 EVRKRCESAEPRHGELWCAVSKDIANWQKKIGDILRLVAGRIKNTF 406
EVRKRCESAEPRHGELWCAVSKDIANWQKKIGDILRLVAGRIKNTF
Sbjct: 361 EVRKRCESAEPRHGELWCAVSKDIANWQKKIGDILRLVAGRIKNTF 406
>gi|40807485 PRP6 pre-mRNA processing factor 6 homolog [Homo
sapiens]
Length = 941
Score = 806 bits (2082), Expect = 0.0
Identities = 397/397 (100%), Positives = 397/397 (100%)
Query: 10 EDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHC 69
EDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHC
Sbjct: 545 EDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHC 604
Query: 70 PKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRL 129
PKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRL
Sbjct: 605 PKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRL 664
Query: 130 LAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEM 189
LAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEM
Sbjct: 665 LAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEM 724
Query: 190 MEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESV 249
MEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESV
Sbjct: 725 MEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESV 784
Query: 250 RLEYRAGLKNIANTLMAKALQECPNSGILWSEAIFLEARPQRRTKSVDALKKCEHDPHVL 309
RLEYRAGLKNIANTLMAKALQECPNSGILWSEAIFLEARPQRRTKSVDALKKCEHDPHVL
Sbjct: 785 RLEYRAGLKNIANTLMAKALQECPNSGILWSEAIFLEARPQRRTKSVDALKKCEHDPHVL 844
Query: 310 LAVAKLFWSQRKITKAREWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKRCESA 369
LAVAKLFWSQRKITKAREWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKRCESA
Sbjct: 845 LAVAKLFWSQRKITKAREWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKRCESA 904
Query: 370 EPRHGELWCAVSKDIANWQKKIGDILRLVAGRIKNTF 406
EPRHGELWCAVSKDIANWQKKIGDILRLVAGRIKNTF
Sbjct: 905 EPRHGELWCAVSKDIANWQKKIGDILRLVAGRIKNTF 941
Score = 113 bits (282), Expect = 4e-25
Identities = 107/433 (24%), Positives = 178/433 (41%), Gaps = 65/433 (15%)
Query: 22 ECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAK 81
+ A+A+ A A++ P +++RAA E + ++ + L++A+ H P + LW +
Sbjct: 356 DTAKAVVAQAVRHLPQSVRIYIRAAELETDIRAKKRV---LRKALEHVPNSVRLWKAAVE 412
Query: 82 SKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPTAR 141
+ + AR +L+ A + P S E+WLA +LE+ YE AR++L KAR + PT R
Sbjct: 413 LE----EPEDARIMLSRAVECCPTSVELWLALARLET----YENARKVLNKARENIPTDR 464
Query: 142 -VFMKSVKLE-------------------------------WVQD----NIRAAQDLCEE 165
+++ + KLE W+QD + + C+
Sbjct: 465 HIWITAAKLEEANGNTQMVEKIIDRAITSLRANGVEINREQWIQDAEECDRAGSVATCQA 524
Query: 166 ALR-------HYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLE 218
+R ED WM +E AR Y L+ P +WL + E
Sbjct: 525 VMRAVIGIGIEEEDRKHTWMEDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFE 584
Query: 219 EKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGIL 278
+ G A+L+++ PK LWL + ++ AG A +++A A Q PNS +
Sbjct: 585 KNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEI 644
Query: 279 WSEAIFLEARPQRRTKSVDALKKCEHD---PHVLLAVAKLFWSQRKITKAREWFHRTVKI 335
W A+ LE+ ++ L K V + KL W Q I A++ ++
Sbjct: 645 WLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRH 704
Query: 336 DSDLGDAWAFFYKFELQHGTEEQQEEVRKRCESAEPRHGELWCAVSKDIANWQKKIGDIL 395
D W + E Q E+ E + P LW +S+ ++KIG +
Sbjct: 705 YEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSR----LEEKIGQLT 760
Query: 396 R----LVAGRIKN 404
R L R+KN
Sbjct: 761 RARAILEKSRLKN 773
Score = 62.8 bits (151), Expect = 5e-10
Identities = 54/215 (25%), Positives = 98/215 (45%), Gaps = 17/215 (7%)
Query: 154 DNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLL 213
++I+ A+ L + P W+ ++EE ++ AR +G + CP S +WL
Sbjct: 289 NDIKKARLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWLE 348
Query: 214 LSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECP 273
+RL+ A+A++ ++ P++ +++ + LE K ++ KAL+ P
Sbjct: 349 AARLQPG----DTAKAVVAQAVRHLPQSVRIYIRAAELETDIRAK---KRVLRKALEHVP 401
Query: 274 NSGILWSEAIFLEARPQRRTKSVDALKKCEHDPHVLLAVAKL--FWSQRKI-TKAREWFH 330
NS LW A+ LE R A++ C + LA+A+L + + RK+ KARE
Sbjct: 402 NSVRLWKAAVELEEPEDARIMLSRAVECCPTSVELWLALARLETYENARKVLNKARE--- 458
Query: 331 RTVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKR 365
+ D + W K E +G + E++ R
Sbjct: 459 -NIPTDRHI---WITAAKLEEANGNTQMVEKIIDR 489
Score = 54.3 bits (129), Expect = 2e-07
Identities = 40/166 (24%), Positives = 69/166 (41%), Gaps = 15/166 (9%)
Query: 221 IGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGILWS 280
I + +AR +L+ R NP +P W+ S RLE G +A L+ K + CP S +W
Sbjct: 288 INDIKKARLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDVWL 347
Query: 281 EAIFLEARPQRRTKSVDALKKCEHDPHVLLAVAKLFW----SQRKITKAREWFHRTVKID 336
EA L+ + A++ + + A+L +R + KA E +V++
Sbjct: 348 EAARLQPGDTAKAVVAQAVRHLPQSVRIYIRAAELETDIRAKKRVLRKALEHVPNSVRL- 406
Query: 337 SDLGDAWAFFYKFELQHGTEEQQEEVRKRCESAEPRHGELWCAVSK 382
+K ++ E + R P ELW A+++
Sbjct: 407 ----------WKAAVELEEPEDARIMLSRAVECCPTSVELWLALAR 442
>gi|124256489 crooked neck-like 1 protein [Homo sapiens]
Length = 848
Score = 61.2 bits (147), Expect = 2e-09
Identities = 68/321 (21%), Positives = 122/321 (38%), Gaps = 27/321 (8%)
Query: 21 LECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGA 80
++ AR+IY AL V ++WL+ A E + + RA+ P+ W
Sbjct: 258 IQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYT 317
Query: 81 KSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPTA 140
+ + G+V AR + + P E+ W + + E E +RAR + + P
Sbjct: 318 YMEEMLGNVAGARQVFERWMEWQP-EEQAWHSYINFELRYKEVDRARTIYERFVLVHPDV 376
Query: 141 RVFMKSVKLEWVQDNIRAAQDLCEEALRHYED---FPKLWMMKGQIEEQKEMMEKAREAY 197
+ ++K + E A+ + E A+ + D L++ + EE ++ E+ R Y
Sbjct: 377 KNWIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAKFEENQKEFERVRVIY 436
Query: 198 NQGLKKC--PHSTPLWLLLSRLEEKIGQ--------LTRARAILEKSRLKNPKNPGLWLE 247
L + + L+ + E+K G +++ R E+ NP N W +
Sbjct: 437 KYALDRISKQDAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFD 496
Query: 248 SVRLEYRAGLKNIANTLMAKALQECP--NSGILWSEAIF----------LEARPQRRTKS 295
+RL + +A+ P W I+ LEA+ RT+
Sbjct: 497 YLRLVESDAEAEAVREVYERAIANVPPIQEKRHWKRYIYLWINYALYEELEAKDPERTRQ 556
Query: 296 VDALKKCEHDPHVLLAVAKLF 316
V E PH AK++
Sbjct: 557 V-YQASLELIPHKKFTFAKMW 576
Score = 46.6 bits (109), Expect = 4e-05
Identities = 35/160 (21%), Positives = 72/160 (45%), Gaps = 3/160 (1%)
Query: 76 WLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKARS 135
W+ A+ + ++ ARSI A + + +WL ++E +N + AR + +A +
Sbjct: 245 WIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAIT 304
Query: 136 SAPTARVF-MKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAR 194
+ P F K +E + N+ A+ + E + ++ + W E + + +++AR
Sbjct: 305 TLPRVNQFWYKYTYMEEMLGNVAGARQVFERWM-EWQPEEQAWHSYINFELRYKEVDRAR 363
Query: 195 EAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKS 234
Y + + P W+ +R EEK AR + E++
Sbjct: 364 TIYERFVLVHP-DVKNWIKYARFEEKHAYFAHARKVYERA 402
Score = 45.8 bits (107), Expect = 7e-05
Identities = 43/214 (20%), Positives = 89/214 (41%), Gaps = 5/214 (2%)
Query: 156 IRAAQDLCEEALRHYEDFPKLWMMKGQIEEQ-KEMMEKAREAYNQGLKKCPHSTPLWLLL 214
I A Q L E R E P K EE+ + + R+ + ++K W+
Sbjct: 189 ITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKY 248
Query: 215 SRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPN 274
++ EE + ++ RAR+I E++ + +N LWL+ +E + N A + +A+ P
Sbjct: 249 AQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPR 308
Query: 275 SGILWSEAIFLE---ARPQRRTKSVDALKKCEHDPHVLLAVAKLFWSQRKITKAREWFHR 331
W + ++E + + + + + + +++ +AR + R
Sbjct: 309 VNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVDRARTIYER 368
Query: 332 TVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKR 365
V + D+ + W + +FE +H +V +R
Sbjct: 369 FVLVHPDVKN-WIKYARFEEKHAYFAHARKVYER 401
Score = 44.7 bits (104), Expect = 2e-04
Identities = 69/291 (23%), Positives = 109/291 (37%), Gaps = 30/291 (10%)
Query: 22 ECARAIYAYALQVFPSKKSVWLRAAY--FEKNHGTRESLEALL--------QRAVAHCPK 71
E R IY YAL + + L Y FEK G R +E ++ + V P
Sbjct: 430 ERVRVIYKYALDRISKQDAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPH 489
Query: 72 AEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEE---------IWLA-AVKLESEND 121
W + + A R + A P +E +W+ A+ E E
Sbjct: 490 NYDAWFDYLRLVESDAEAEAVREVYERAIANVPPIQEKRHWKRYIYLWINYALYEELEAK 549
Query: 122 EYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQ-DLCEEAL-RHYEDFPKLWMM 179
+ ER R++ + P + + + + Q IR L AL PK +
Sbjct: 550 DPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSIGKCPKNKLF 609
Query: 180 KGQIEEQKEMME--KAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILE----K 233
K IE + ++ E + R+ Y + L+ P + W+ + LE +G + RARAI E +
Sbjct: 610 KVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIDRARAIYELAISQ 669
Query: 234 SRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGILWSEAIF 284
RL P+ LW + E L + LQ + + S A F
Sbjct: 670 PRLDMPE--VLWKSYIDFEIEQEETERTRNLYRRLLQRTQHVKVWISFAQF 718
Score = 40.4 bits (93), Expect = 0.003
Identities = 38/194 (19%), Positives = 77/194 (39%), Gaps = 4/194 (2%)
Query: 40 SVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALA 99
S W++ A +E++ + ++ +RA+ + LWL A+ + V AR+I A
Sbjct: 243 SNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRA 302
Query: 100 FQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAA 159
P + W +E AR++ + P + + + E + A
Sbjct: 303 ITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVDRA 362
Query: 160 QDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPH---STPLWLLLSR 216
+ + E + + D K W+ + EE+ AR+ Y + ++ L++ ++
Sbjct: 363 RTIYERFVLVHPDV-KNWIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAK 421
Query: 217 LEEKIGQLTRARAI 230
EE + R R I
Sbjct: 422 FEENQKEFERVRVI 435
>gi|70980549 programmed cell death 11 [Homo sapiens]
Length = 1871
Score = 52.8 bits (125), Expect = 6e-07
Identities = 37/200 (18%), Positives = 81/200 (40%), Gaps = 7/200 (3%)
Query: 64 RAVAHCPKAEVLWLMGAKSKWLAGDVPAARSIL-----ALAFQANPNSEEIWLAAVKLES 118
R V P + +LWL A ++ AR++ ++F+ +W+A + LE+
Sbjct: 1610 RLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLEN 1669
Query: 119 ENDEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWM 178
E ++ +A +VF+ + + + A +L L+ + +W+
Sbjct: 1670 MYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWI 1729
Query: 179 MKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLL--LSRLEEKIGQLTRARAILEKSRL 236
G ++ + + L+ P + ++ ++LE ++G RA+AI E +
Sbjct: 1730 KYGAFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLS 1789
Query: 237 KNPKNPGLWLESVRLEYRAG 256
PK +W + + + G
Sbjct: 1790 TYPKRTDVWSVYIDMTIKHG 1809
Score = 49.3 bits (116), Expect = 6e-06
Identities = 55/276 (19%), Positives = 112/276 (40%), Gaps = 44/276 (15%)
Query: 102 ANPNSEEIWLAAVKLESENDEYERARRLLAKA------RSSAPTARVFMKSVKLEWVQDN 155
++PNS +WL + + E E+AR + +A R V++ + LE + +
Sbjct: 1614 SSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGS 1673
Query: 156 IRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLS 215
+ + E A+++ E K+++ I + E ++A E YN+ LK+ +W+
Sbjct: 1674 QESLTKVFERAVQYNEPL-KVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYG 1732
Query: 216 RLEEKIGQLTRARAILEKSR--LKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECP 273
+ Q + +L+++ L + ++ + + +LE++ G A + L P
Sbjct: 1733 AFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYP 1792
Query: 274 NSGILWSEAIFLEARPQRRTKSVDALKKCEHDPHVLLAVAKLFWSQRKITKAREWFHRTV 333
+WS I + + SQ+ + R+ F R +
Sbjct: 1793 KRTDVWSVYIDMTIK---------------------------HGSQKDV---RDIFERVI 1822
Query: 334 KIDSDLGDAWAFFYK----FELQHGTEEQQEEVRKR 365
+ S FF+K +E QHGTE+ + V+ +
Sbjct: 1823 HL-SLAPKRMKFFFKRYLDYEKQHGTEKDVQAVKAK 1857
Score = 35.0 bits (79), Expect = 0.12
Identities = 24/123 (19%), Positives = 51/123 (41%), Gaps = 2/123 (1%)
Query: 12 ADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPK 71
AD + A +Y L+ F +K+VW++ F + +LQRA+ P
Sbjct: 1698 ADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRSQAAASHRVLQRALECLPS 1757
Query: 72 AEVLWLMG--AKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRL 129
E + ++ A+ ++ GD A++I P ++W + + ++ + R +
Sbjct: 1758 KEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTDVWSVYIDMTIKHGSQKDVRDI 1817
Query: 130 LAK 132
+
Sbjct: 1818 FER 1820
Score = 32.3 bits (72), Expect = 0.79
Identities = 36/168 (21%), Positives = 66/168 (39%), Gaps = 15/168 (8%)
Query: 21 LECARAIYAYALQVFP-----SKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVL 75
+E ARA+ AL+ K +VW+ E +G++ESL + +RAV + +V
Sbjct: 1635 IEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFERAVQYNEPLKVF 1694
Query: 76 WLMG---AKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAK 132
+ AKS+ A + + + +W+ + + R+L +
Sbjct: 1695 LHLADIYAKSE----KFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRSQAAASHRVLQR 1750
Query: 133 ARSSAPTAR---VFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLW 177
A P+ V K +LE+ + A+ + E L Y +W
Sbjct: 1751 ALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTDVW 1798
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 47.8 bits (112), Expect = 2e-05
Identities = 49/220 (22%), Positives = 93/220 (42%), Gaps = 10/220 (4%)
Query: 22 ECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAK 81
E A A Y A+++ PS + ++ G E +RA+ KAE+L +GA
Sbjct: 525 EKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAEILSPLGAL 584
Query: 82 SKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLES---ENDEYERARRLLAKARSSAP 138
+ G A I A P+ E+ LA ++ + + E E+ + +
Sbjct: 585 Y-YNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCL 643
Query: 139 TARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPK----LWMMKGQIEEQKEMMEKAR 194
+ ++ + Q+N A D ++AL+ PK L+ KG ++ +++KA
Sbjct: 644 ECYRLLSAIYSK--QENHDKALDAIDKALQLKPKDPKVISELFFTKGNQLREQNLLDKAF 701
Query: 195 EAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKS 234
E+Y ++ P W+ + ++ G+ ARA E++
Sbjct: 702 ESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERA 741
Score = 42.0 bits (97), Expect = 0.001
Identities = 74/364 (20%), Positives = 133/364 (36%), Gaps = 53/364 (14%)
Query: 26 AIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPK-AEVLWLMGAKSKW 84
+++ +Q P V A F K+ G + + A+ P+ A L +G
Sbjct: 362 SLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGT---- 417
Query: 85 LAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPT-ARVF 143
L D A+ A Q +P L ++ E A LL + P A +
Sbjct: 418 LTRDTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAY 477
Query: 144 MKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKK 203
L Q+ + A+++ + +++ D L G + EKA Y Q +K
Sbjct: 478 SSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKL 537
Query: 204 CPHSTPLWLLLSRLEEKIGQ-------LTRARAILEKSRLKNP-----KNPGLWLESVRL 251
P + L RL +G+ RA + K+ + +P N G + E++++
Sbjct: 538 SPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAEILSPLGALYYNTGRYEEALQI 597
Query: 252 ------------EYRAGLKNIANTLMAKALQECPNSGILWSEAIFLE---------ARPQ 290
E R L + + E + I+ E LE ++ +
Sbjct: 598 YQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQE 657
Query: 291 RRTKSVDALKKC----EHDPHVLLAVAKLFWS-------QRKITKAREWFHRTVKIDSDL 339
K++DA+ K DP V +++LF++ Q + KA E + V+++ D
Sbjct: 658 NHDKALDAIDKALQLKPKDPKV---ISELFFTKGNQLREQNLLDKAFESYRVAVQLNPDQ 714
Query: 340 GDAW 343
AW
Sbjct: 715 AQAW 718
>gi|55770906 XPA binding protein 2 [Homo sapiens]
Length = 855
Score = 46.6 bits (109), Expect = 4e-05
Identities = 77/332 (23%), Positives = 134/332 (40%), Gaps = 41/332 (12%)
Query: 71 KAEVLWLMGAKSKWLAGDVPAARSILALAFQAN----PNSEEIWLAAVKLESENDEYERA 126
K LW+ AK G + AR IL A + N + +W +LE ++ Y+ A
Sbjct: 393 KPHTLWVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLASVWCQCGELELRHENYDEA 452
Query: 127 RRLLAKARS-----------SAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPK 175
RLL KA + S P KS+K+ + ++ + + Y+
Sbjct: 453 LRLLRKATALPARRAEYFDGSEPVQNRVYKSLKVWSMLADLEESLGTFQSTKAVYDRILD 512
Query: 176 LWMMKGQIE-------EQKEMMEKAREAYNQGLK--KCPHSTPLW-LLLSRLEEKIG--Q 223
L + QI E+ + E++ +AY +G+ K P+ + +W L++ + G +
Sbjct: 513 LRIATPQIVINYAMFLEEHKYFEESFKAYERGISLFKWPNVSDIWSTYLTKFIARYGGRK 572
Query: 224 LTRARAILEKSRLKNPKNPG--LWLESVRLEYRAGLKNIANTLMAKAL------QECPNS 275
L RAR + E++ P L+L +LE GL A + +A Q+
Sbjct: 573 LERARDLFEQALDGCPPKYAKTLYLLYAQLEEEWGLARHAMAVYERATRAVEPAQQYDMF 632
Query: 276 GILWSEAIFLEARPQRR---TKSVDALKKCEHDPHVLLAVAKLFWSQRKITKAREWFHRT 332
I A + R K+++ L EH + L A + +I +AR +
Sbjct: 633 NIYIKRAAEIYGVTHTRGIYQKAIEVLSD-EHAREMCLRFADMECKLGEIDRARAIYSFC 691
Query: 333 VKI--DSDLGDAWAFFYKFELQHGTEEQQEEV 362
+I G W + FE++HG E+ +E+
Sbjct: 692 SQICDPRTTGAFWQTWKDFEVRHGNEDTIKEM 723
Score = 35.8 bits (81), Expect = 0.071
Identities = 59/240 (24%), Positives = 100/240 (41%), Gaps = 19/240 (7%)
Query: 33 QVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAV---AHCPKAEVLWLMGAKS-KWLAGD 88
+V+ S K VW A E++ GT +S +A+ R + P+ + + M + K+
Sbjct: 479 RVYKSLK-VWSMLADLEESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEES 537
Query: 89 VPAARSILALAFQANPNSEEIW---LAAVKLESENDEYERARRLLAKARSSAP---TARV 142
A ++L PN +IW L + ERAR L +A P +
Sbjct: 538 FKAYERGISLFKW--PNVSDIWSTYLTKFIARYGGRKLERARDLFEQALDGCPPKYAKTL 595
Query: 143 FMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEM--MEKAREAYNQG 200
++ +LE R A + E A R E + M I+ E+ + R Y +
Sbjct: 596 YLLYAQLEEEWGLARHAMAVYERATRAVEPAQQYDMFNIYIKRAAEIYGVTHTRGIYQKA 655
Query: 201 LKKCP--HSTPLWLLLSRLEEKIGQLTRARAILE-KSRLKNPKNPG-LWLESVRLEYRAG 256
++ H+ + L + +E K+G++ RARAI S++ +P+ G W E R G
Sbjct: 656 IEVLSDEHAREMCLRFADMECKLGEIDRARAIYSFCSQICDPRTTGAFWQTWKDFEVRHG 715
Score = 34.3 bits (77), Expect = 0.21
Identities = 44/191 (23%), Positives = 83/191 (43%), Gaps = 30/191 (15%)
Query: 100 FQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAA 159
F+A +W+A K +N + + AR +L KA +V K V D++ +
Sbjct: 388 FKATGKPHTLWVAFAKFYEDNGQLDDARVILEKA------TKVNFKQV------DDLASV 435
Query: 160 QDLCEE-ALRH--YEDFPKLWMMKGQIEEQK-EMMEKAREAYNQGLKKCPHSTPLWLLLS 215
C E LRH Y++ +L + ++ E + + N+ K S +W +L+
Sbjct: 436 WCQCGELELRHENYDEALRLLRKATALPARRAEYFDGSEPVQNRVYK----SLKVWSMLA 491
Query: 216 RLEEKIGQLTRARAILEK---SRLKNPK---NPGLWLESVRLEYRAGLKNIANTLMAKAL 269
LEE +G +A+ ++ R+ P+ N ++LE E++ ++ +L
Sbjct: 492 DLEESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLE----EHKYFEESFKAYERGISL 547
Query: 270 QECPNSGILWS 280
+ PN +WS
Sbjct: 548 FKWPNVSDIWS 558
Score = 32.7 bits (73), Expect = 0.60
Identities = 78/393 (19%), Positives = 140/393 (35%), Gaps = 42/393 (10%)
Query: 15 CVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAE- 73
CV A E + A +WL F + G RA+ P +
Sbjct: 86 CVTDPAYEDVNNCHERAFVFMHKMPRLWLDYCQFLMDQGRVTHTRRTFDRALRALPITQH 145
Query: 74 ----VLWLMGAKSKWLAGD-VPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARR 128
L+L +S L V R L L+ P S E ++ +K DE A+R
Sbjct: 146 SRIWPLYLRFLRSHPLPETAVRGYRRFLKLS----PESAEEYIEYLKSSDRLDE--AAQR 199
Query: 129 LLAKARSSAPTARVFMKSVKL-----EWVQDNIRAAQDLCEEAL------RHYEDFPKLW 177
L ++ + +L + + N Q L +A+ R + KLW
Sbjct: 200 LATVVNDERFVSKAGKSNYQLWHELCDLISQNPDKVQSLNVDAIIRGGLTRFTDQLGKLW 259
Query: 178 MMKGQIEEQKEMMEKAREAYNQGLK---KCPHSTPLWLLLSRLEEKIGQLTRARAILEKS 234
+ EKAR+ Y + ++ T ++ ++ EE + A + S
Sbjct: 260 CSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESM----IAAKMETAS 315
Query: 235 RLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGILWSEAIFL-EARPQR-- 291
L + + LE + + L + L++ P+ W + + L + RP+
Sbjct: 316 ELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKRVALHQGRPREII 375
Query: 292 --RTKSVDALK--KCEHDPHVL-LAVAKLFWSQRKITKAREWFHRTVKID----SDLGDA 342
T++V + K PH L +A AK + ++ AR + K++ DL
Sbjct: 376 NTYTEAVQTVDPFKATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVNFKQVDDLASV 435
Query: 343 WAFFYKFELQHGTEEQQEEVRKRCESAEPRHGE 375
W + EL+H ++ + ++ + R E
Sbjct: 436 WCQCGELELRHENYDEALRLLRKATALPARRAE 468
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 40.8 bits (94), Expect = 0.002
Identities = 57/262 (21%), Positives = 96/262 (36%), Gaps = 14/262 (5%)
Query: 12 ADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPK 71
A + VA +E A Y ALQ P V K G E +A +A+ P
Sbjct: 120 AAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPN 179
Query: 72 AEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLA 131
V W G++ A A +PN + ++ + E ++RA
Sbjct: 180 FAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYL 239
Query: 132 KARSSAPTARVFMKSVKLEWVQDN-IRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMM 190
+A S +P V ++ + + I A D A+ FP + ++K +
Sbjct: 240 RALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSV 299
Query: 191 EKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVR 250
+A + YN L+ CP L+ ++ + G + A + K+ P
Sbjct: 300 AEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFP----------- 348
Query: 251 LEYRAGLKNIANTLMAKA-LQE 271
E+ A N+A+ L + LQE
Sbjct: 349 -EFAAAHSNLASVLQQQGKLQE 369
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 40.8 bits (94), Expect = 0.002
Identities = 57/262 (21%), Positives = 96/262 (36%), Gaps = 14/262 (5%)
Query: 12 ADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPK 71
A + VA +E A Y ALQ P V K G E +A +A+ P
Sbjct: 130 AAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPN 189
Query: 72 AEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLA 131
V W G++ A A +PN + ++ + E ++RA
Sbjct: 190 FAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYL 249
Query: 132 KARSSAPTARVFMKSVKLEWVQDN-IRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMM 190
+A S +P V ++ + + I A D A+ FP + ++K +
Sbjct: 250 RALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSV 309
Query: 191 EKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVR 250
+A + YN L+ CP L+ ++ + G + A + K+ P
Sbjct: 310 AEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFP----------- 358
Query: 251 LEYRAGLKNIANTLMAKA-LQE 271
E+ A N+A+ L + LQE
Sbjct: 359 -EFAAAHSNLASVLQQQGKLQE 379
>gi|156938331 PRP39 pre-mRNA processing factor 39 homolog [Homo
sapiens]
Length = 669
Score = 40.8 bits (94), Expect = 0.002
Identities = 40/184 (21%), Positives = 76/184 (41%), Gaps = 9/184 (4%)
Query: 42 WLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQ 101
W FE +GT E + L +R V C E W+ AK + R + + A
Sbjct: 356 WKEYLEFEIENGTHERVVVLFERCVISCALYEEFWIKYAK-YMENHSIEGVRHVFSRACT 414
Query: 102 AN-PNSEEIWLAAVKLESENDEYERARRLLAKARSSA-PTARVFMKSVKLEWVQDNIRAA 159
+ P + + E + AR +L A V ++ V LE N+ A
Sbjct: 415 IHLPKKPMVHMLWAAFEEQQGNINEARNILKTFEECVLGLAMVRLRRVSLERRHGNLEEA 474
Query: 160 QDLCEEALRHYE-----DFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLL 214
+ L ++A+++ + F + + + + QK + K+R+ + +++ +T L+L L
Sbjct: 475 EHLLQDAIKNAKSNNESSFYAVKLARHLFKIQKN-LPKSRKVLLEAIERDKENTKLYLNL 533
Query: 215 SRLE 218
+E
Sbjct: 534 LEME 537
Score = 32.7 bits (73), Expect = 0.60
Identities = 37/176 (21%), Positives = 71/176 (40%), Gaps = 19/176 (10%)
Query: 41 VWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSK----WLAGDVPAARSIL 96
V LR E+ HG E E LLQ A+ + K + ++P +R +L
Sbjct: 457 VRLRRVSLERRHGNLEEAEHLLQDAIKNAKSNNESSFYAVKLARHLFKIQKNLPKSRKVL 516
Query: 97 ALAFQANPNSEEIWLAAVKLESENDEYERARRLL----AKARSSAP-TARVFMKSVKLEW 151
A + + + +++L +++E D + +L S P R+ K+E+
Sbjct: 517 LEAIERDKENTKLYLNLLEMEYSGDLKQNEENILNCFDKAVHGSLPIKMRITFSQRKVEF 576
Query: 152 VQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHS 207
++D D+ + L Y++ L ++EQ + KA + +K H+
Sbjct: 577 LED---FGSDV-NKLLNAYDEHQTL------LKEQDSLKRKAENGSEEPEEKKAHT 622
Score = 32.0 bits (71), Expect = 1.0
Identities = 14/60 (23%), Positives = 30/60 (50%)
Query: 153 QDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWL 212
++++ AA+ + HY W +E++ + ++ + E Y +GL+ P S LW+
Sbjct: 108 ENHLMAARKAFDRFFIHYPYCYGYWKKYADLEKRHDNIKPSDEVYRRGLQAIPLSVDLWI 167
>gi|7110679 tetratricopeptide repeat domain 33 [Homo sapiens]
Length = 262
Score = 39.3 bits (90), Expect = 0.006
Identities = 37/148 (25%), Positives = 59/148 (39%), Gaps = 17/148 (11%)
Query: 105 NSEEIWLAAVKLESE---NDEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQD 161
N E WL A+K E E++++L + S A R R A
Sbjct: 35 NDEGNWLHAIKRRKEILLEGCAEKSKQLKDEGASLAENKRY--------------REAIQ 80
Query: 162 LCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKI 221
+EAL+ + L+ MK Q+ M A A +++ PHS W L R + +
Sbjct: 81 KWDEALQLTPNDATLYEMKSQVLMSLHEMFPAVHAAEMAVQQNPHSWESWQTLGRAQLGL 140
Query: 222 GQLTRARAILEKSRLKNPKNPGLWLESV 249
G++ A + + P NP +W E +
Sbjct: 141 GEIILAIRSFQVALHIYPMNPEIWKEDL 168
>gi|224809432 transmembrane and tetratricopeptide repeat containing
3 [Homo sapiens]
Length = 914
Score = 38.9 bits (89), Expect = 0.008
Identities = 34/190 (17%), Positives = 75/190 (39%), Gaps = 27/190 (14%)
Query: 153 QDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWL 212
+ + A L +A+ DF + ++ +G++ + KA+EAY + L+ ++ LW
Sbjct: 542 ESRLEEADQLYRQAISMRPDFKQAYISRGELLLKMNKPLKAKEAYLKALELDRNNADLWY 601
Query: 213 LLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQEC 272
L+ + ++ + A ++ NPK+
Sbjct: 602 NLAIVHIELKEPNEALKNFNRALELNPKHKLALF-------------------------- 635
Query: 273 PNSGILWSEAIFLEARPQRRTKSVDALKKCEHDPHVLLAVAKLFWSQRKITKAREWFHRT 332
NS I+ E+ ++ RP+ R + + + + D + + L +K +A W +
Sbjct: 636 -NSAIVMQESGEVKLRPEARKRLLSYINEEPLDANGYFNLGMLAMDDKKDNEAEIWMKKA 694
Query: 333 VKIDSDLGDA 342
+K+ +D A
Sbjct: 695 IKLQADFRSA 704
>gi|7661952 squamous cell carcinoma antigen recognized by T cells 3
[Homo sapiens]
Length = 963
Score = 37.0 bits (84), Expect = 0.032
Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Query: 218 EEKIGQLTRARAILEKSRLKNPKNPGLWLE-SVRLEYRAGLKNIANTLMAKALQECPNSG 276
E KIG R + I E++ ++N P LW+ S L+ + +K++ ++ +A++ CP +
Sbjct: 320 EMKIGDPARIQLIFERALVENCLVPDLWIRYSQYLDRQLKVKDLVLSVHNRAIRNCPWTV 379
Query: 277 ILWSEAIFLEAR 288
LWS + R
Sbjct: 380 ALWSRYLLAMER 391
Score = 31.2 bits (69), Expect = 1.8
Identities = 42/201 (20%), Positives = 75/201 (37%), Gaps = 31/201 (15%)
Query: 40 SVWLRAAYFEKN----HGTRESLEALLQRAVA----HCPKAEVLWLMGAKSKWLAGDVPA 91
++WL + G E + ++ +RA++ H K LW A ++ + V A
Sbjct: 184 NIWLEYGQYSVGGIGQKGGLEKVRSVFERALSSVGLHMTKGLALW--EAYREFESAIVEA 241
Query: 92 AR------------SILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKAR----- 134
AR +I +A E W ES Y +A + L K +
Sbjct: 242 ARLEKVHSLFRRQLAIPLYDMEATFAEYEEWSEDPIPESVIQNYNKALQQLEKYKPYEEA 301
Query: 135 ---SSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQ-IEEQKEMM 190
+ AP + + E + Q + E AL P LW+ Q ++ Q ++
Sbjct: 302 LLQAEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENCLVPDLWIRYSQYLDRQLKVK 361
Query: 191 EKAREAYNQGLKKCPHSTPLW 211
+ +N+ ++ CP + LW
Sbjct: 362 DLVLSVHNRAIRNCPWTVALW 382
Score = 29.3 bits (64), Expect = 6.7
Identities = 48/179 (26%), Positives = 75/179 (41%), Gaps = 17/179 (9%)
Query: 112 AAVKLESENDEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEE--ALRH 169
A K + E DE +A R K S A A + K++ W Q ++ +E
Sbjct: 18 AGPKADGEEDEV-KAARTRRKVLSRAVAAATY-KTMGPAWDQQEEGVSESDGDEYAMASS 75
Query: 170 YEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLL-LSRLEEKIGQLTRAR 228
E P + + EE+K +E R + ++ + L+ L RLE G+LT+ R
Sbjct: 76 AESSPGEYEWEYDEEEEKNQLEIERLEEQLSINVYDYNCHVDLIRLLRLE---GELTKVR 132
Query: 229 AILEKSRLKNPKNPGLWLESVRLEY---RAGL-KNIANTLMAKALQE--CPNSGILWSE 281
+K P LWLE + E + GL + L KA+++ CPN +W E
Sbjct: 133 MARQKMSEIFPLTEELWLEWLHDEISMAQDGLDREHVYDLFEKAVKDYICPN---IWLE 188
>gi|118766328 transmembrane and tetratricopeptide repeat containing
4 isoform 2 [Homo sapiens]
Length = 741
Score = 36.6 bits (83), Expect = 0.042
Identities = 37/178 (20%), Positives = 70/178 (39%), Gaps = 6/178 (3%)
Query: 153 QDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWL 212
++ ++ A++L A++ DF WM G ++ + E A ++Y +K +
Sbjct: 529 RNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYY 588
Query: 213 LLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQEC 272
L RL + + A + + P++ W + L G A + +AL+
Sbjct: 589 NLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALELI 648
Query: 273 PNS-GILWSEAIFLEARPQRRTKSVDALKKCEHDP-----HVLLAVAKLFWSQRKITK 324
PN +++S A L + + LK + +P H LAV W + K
Sbjct: 649 PNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDLAK 706
>gi|118766330 transmembrane and tetratricopeptide repeat containing
4 isoform 1 [Homo sapiens]
Length = 760
Score = 36.6 bits (83), Expect = 0.042
Identities = 37/178 (20%), Positives = 70/178 (39%), Gaps = 6/178 (3%)
Query: 153 QDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWL 212
++ ++ A++L A++ DF WM G ++ + E A ++Y +K +
Sbjct: 548 RNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYY 607
Query: 213 LLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQEC 272
L RL + + A + + P++ W + L G A + +AL+
Sbjct: 608 NLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALELI 667
Query: 273 PNS-GILWSEAIFLEARPQRRTKSVDALKKCEHDP-----HVLLAVAKLFWSQRKITK 324
PN +++S A L + + LK + +P H LAV W + K
Sbjct: 668 PNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDLAK 725
>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
Length = 284
Score = 35.4 bits (80), Expect = 0.093
Identities = 45/184 (24%), Positives = 75/184 (40%), Gaps = 30/184 (16%)
Query: 73 EVLWLMGAKSKWLAGDVPAA-RSILALAFQANPNSEEIWLAAVKLESEN---DEYERARR 128
E L L K+ GDV A R I + + + E + A KLE DE ER +
Sbjct: 69 EKLELTEKKASDAEGDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMK 128
Query: 129 LLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFP-KLWMMKGQIEEQK 187
++ R K+E + ++ A+ + EEA R YE+ KL +++G++E +
Sbjct: 129 VIEN--------RAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAE 180
Query: 188 EMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLE 247
E E + L LEE++ +T LE + K + + E
Sbjct: 181 ERAEVSE-----------------LKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEE 223
Query: 248 SVRL 251
++L
Sbjct: 224 EIKL 227
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 35.4 bits (80), Expect = 0.093
Identities = 59/240 (24%), Positives = 96/240 (40%), Gaps = 36/240 (15%)
Query: 19 NALECARAIYAYALQVFPSKKSVWLR---AAYFEKNHGTRESLEALLQRAVAHCPKAEVL 75
NAL+ RA A A Q ++S L AA +K GT + L+ + K E+
Sbjct: 18 NALD--RAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELA 75
Query: 76 WLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESEN---DEYERARRLLAK 132
A ++ A R I + + + E + A KLE DE ER +++
Sbjct: 76 EKKAADAE--AEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIEN 133
Query: 133 ARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFP-KLWMMKGQIEEQKEMME 191
R K+E + ++ A+ + EEA R YE+ KL +++G +E +E E
Sbjct: 134 --------RALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAE 185
Query: 192 KAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRL 251
A KC S LEE++ +T LE K + + E +++
Sbjct: 186 LAE-------SKC----------SELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKI 228
>gi|52630440 FK506-binding protein 8 [Homo sapiens]
Length = 413
Score = 35.0 bits (79), Expect = 0.12
Identities = 46/183 (25%), Positives = 67/183 (36%), Gaps = 28/183 (15%)
Query: 107 EEIWLAAVKLESENDEYERARRLLAK---------ARSSAPTARVFMKSVKLEWVQ---- 153
E + LA K E N Y+RA +LA SSA F + +L ++
Sbjct: 217 ERVALANRKRECGNAHYQRADFVLAANSYDLAIKAITSSAKVDMTFEEEAQLLQLKVKCL 276
Query: 154 ----------DNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKK 203
D+ RAA C L H D K KG++ Q+ +A LK
Sbjct: 277 NNLAASQLKLDHYRAALRSCSLVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKL 336
Query: 204 CPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNP-----KNPGLWLESVRLEYRAGLK 258
P + + LS+L +K L + L NP K PG S+ ++ G
Sbjct: 337 EPSNKTIHAELSKLVKKHAAQRSTETALYRKMLGNPSRLPAKCPGKGAWSIPWKWLFGAT 396
Query: 259 NIA 261
+A
Sbjct: 397 AVA 399
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 34.7 bits (78), Expect = 0.16
Identities = 49/189 (25%), Positives = 88/189 (46%), Gaps = 25/189 (13%)
Query: 52 HGTRESLEALLQRAVAHCPKAE-VLWLMGAKSKWLAGDVPAARSIL----ALAFQANPNS 106
H T SL++ L+RA +A+ L+ A + L V ++ + A A A
Sbjct: 1319 HETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILE 1378
Query: 107 EEIWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEA 166
E++ A L+ +N+E E R R+ A + +K + + +Q+N+ L +
Sbjct: 1379 EDLRTARSALKLKNEEVESERE-----RAQALQEQGELKVAQGKALQENLA----LLTQT 1429
Query: 167 LRHYEDFPKLWMMKGQIEE---QKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQ 223
L E+ ++ ++GQI+E Q+EM + A E + LKK L +E+I +
Sbjct: 1430 LAEREE--EVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDL------QQEQIQE 1481
Query: 224 LTRARAILE 232
L + R++LE
Sbjct: 1482 LEKCRSVLE 1490
>gi|49574529 hepatocellular carcinoma-associated antigen 66 [Homo
sapiens]
Length = 597
Score = 34.7 bits (78), Expect = 0.16
Identities = 28/132 (21%), Positives = 55/132 (41%), Gaps = 17/132 (12%)
Query: 6 SWHEEDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRA 65
S+ +++ ++ + H + ++ A + +WL F K T+ L +
Sbjct: 78 SFKKDEIENSIVHRV----QGVFQRASAKWKDDVQLWLSYVAFCKKWATKTRLSKVFSAM 133
Query: 66 VAHCPKAEVLWLMGAKSKWLAGD---VPAARSILALAFQANPNSEEIW--------LAAV 114
+A LW+M A KW D +AR + A + +P +++ + A
Sbjct: 134 LAIHSNKPALWIMAA--KWEMEDRLSSESARQLFLRALRFHPECPKLYKEYFRMELMHAE 191
Query: 115 KLESENDEYERA 126
KL E +E+E+A
Sbjct: 192 KLRKEKEEFEKA 203
>gi|110225358 tetratricopeptide repeat domain 7A [Homo sapiens]
Length = 858
Score = 34.7 bits (78), Expect = 0.16
Identities = 25/123 (20%), Positives = 57/123 (46%), Gaps = 2/123 (1%)
Query: 111 LAAVKLESENDEYERARRLLAKARSSAPTA--RVFMKSVKLEWVQDNIRAAQDLCEEALR 168
+AA +LE E +L + T ++++++ +L Q +++ A +EA
Sbjct: 680 IAASRLEEAMSELTMPSSVLKQGPMQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAG 739
Query: 169 HYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRAR 228
+ + M+G++ E K +E+A++ Y + L P + L + ++G + A+
Sbjct: 740 LFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQ 799
Query: 229 AIL 231
+L
Sbjct: 800 KVL 802
Score = 30.4 bits (67), Expect = 3.0
Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 107 EEIWLAAVKLESENDEYERARRLLAKARSSAPTAR-VFMKSVKLEWVQDNIRAAQDLCEE 165
E+IWL A +L E + A + +A PT+ V +L V+ N+ A+ L +E
Sbjct: 711 EQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKE 770
Query: 166 AL 167
AL
Sbjct: 771 AL 772
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 34.3 bits (77), Expect = 0.21
Identities = 36/138 (26%), Positives = 57/138 (41%), Gaps = 11/138 (7%)
Query: 101 QANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSVKLEW----VQDNI 156
QA P S L ++E N +YE +LL A+ A KS++ W +N
Sbjct: 575 QALPGSGTTPLLRTRVEDTNRKYEHLLQLLDLAQEKVDVANRLEKSLQQSWELLATHENH 634
Query: 157 RAAQDLCEEALRHYED-FPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLS 215
D E+ R + +L M +++ QK ++ + E Q K+C + L S
Sbjct: 635 LNQDDTVPESSRVLDSKGQELAAMACELQAQKSLLGEV-EQNLQAAKQCSST-----LAS 688
Query: 216 RLEEKIGQLTRARAILEK 233
R +E L R A + K
Sbjct: 689 RFQEHCPDLERQEAEVHK 706
>gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens]
Length = 248
Score = 33.9 bits (76), Expect = 0.27
Identities = 41/170 (24%), Positives = 70/170 (41%), Gaps = 30/170 (17%)
Query: 87 GDVPAA-RSILALAFQANPNSEEIWLAAVKLESEN---DEYERARRLLAKARSSAPTARV 142
GDV A R I + + + E + A KLE DE ER +++ R
Sbjct: 47 GDVAALNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIEN--------RA 98
Query: 143 FMKSVKLEWVQDNIRAAQDLCEEALRHYEDFP-KLWMMKGQIEEQKEMMEKAREAYNQGL 201
K+E + ++ A+ + EEA R YE+ KL +++G++E +E E +
Sbjct: 99 MKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEVSE------- 151
Query: 202 KKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRL 251
L LEE++ +T LE + K + + E ++L
Sbjct: 152 ----------LKCGDLEEELKNVTNNLKSLEAASEKYSEKEDKYEEEIKL 191
>gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens]
Length = 247
Score = 33.9 bits (76), Expect = 0.27
Identities = 37/149 (24%), Positives = 61/149 (40%), Gaps = 29/149 (19%)
Query: 107 EEIWLAAVKLESEN---DEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLC 163
E + A KLE DE ER +++ R K+E + ++ A+ +
Sbjct: 68 ERLATALQKLEEAEKAADESERGMKVIEN--------RALKDEEKMELQEIQLKEAKHIA 119
Query: 164 EEALRHYEDFP-KLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIG 222
EEA R YE+ KL +++G +E +E E A KC S LEE++
Sbjct: 120 EEADRKYEEVARKLVIIEGDLERTEERAELAE-------SKC----------SELEEELK 162
Query: 223 QLTRARAILEKSRLKNPKNPGLWLESVRL 251
+T LE K + + E +++
Sbjct: 163 NVTNNLKSLEAQAEKYSQKEDKYEEEIKI 191
>gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]
Length = 248
Score = 33.9 bits (76), Expect = 0.27
Identities = 37/149 (24%), Positives = 61/149 (40%), Gaps = 29/149 (19%)
Query: 107 EEIWLAAVKLESEN---DEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLC 163
E + A KLE DE ER +++ R K+E + ++ A+ +
Sbjct: 68 ERLATALQKLEEAEKAADESERGMKVIEN--------RALKDEEKMELQEIQLKEAKHIA 119
Query: 164 EEALRHYEDFP-KLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIG 222
EEA R YE+ KL +++G +E +E E A KC S LEE++
Sbjct: 120 EEADRKYEEVARKLVIIEGDLERTEERAELAE-------SKC----------SELEEELK 162
Query: 223 QLTRARAILEKSRLKNPKNPGLWLESVRL 251
+T LE K + + E +++
Sbjct: 163 NVTNNLKSLEAQAEKYSQKEDKYEEEIKI 191
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 33.5 bits (75), Expect = 0.35
Identities = 16/90 (17%), Positives = 44/90 (48%), Gaps = 1/90 (1%)
Query: 115 KLESENDEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHY-EDF 173
K+ + ++ + ++ + + A+++ + K+ ++ IR +++ +E E
Sbjct: 358 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQE 417
Query: 174 PKLWMMKGQIEEQKEMMEKAREAYNQGLKK 203
K+W + +++EQ+E M + E + KK
Sbjct: 418 EKMWEQEEEMQEQEEKMRRQEEKIREQEKK 447
>gi|167466177 cell division cycle protein 27 isoform 1 [Homo
sapiens]
Length = 830
Score = 33.5 bits (75), Expect = 0.35
Identities = 36/185 (19%), Positives = 76/185 (41%), Gaps = 3/185 (1%)
Query: 119 ENDEYERARRLLAKAR--SSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKL 176
E EY +A R+ ++ R + + + S L +Q ++ A L ++ ++ P+
Sbjct: 517 ELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDV-ALSVLSKDLTDMDKNSPEA 575
Query: 177 WMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRL 236
W G + + A + + + ++ P+ + LL +L +A A +
Sbjct: 576 WCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIR 635
Query: 237 KNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGILWSEAIFLEARPQRRTKSV 296
NP++ W + Y+ ++A KAL P S +L ++ ++ K++
Sbjct: 636 VNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKAL 695
Query: 297 DALKK 301
D L K
Sbjct: 696 DTLNK 700
Score = 32.0 bits (71), Expect = 1.0
Identities = 32/139 (23%), Positives = 55/139 (39%), Gaps = 1/139 (0%)
Query: 105 NSEEIWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSVKLEWV-QDNIRAAQDLC 163
NS E W AA S E++ A + +A P + E+V + + A
Sbjct: 571 NSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACF 630
Query: 164 EEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQ 223
A+R W G I ++E A + + L P S+ L + ++ + +
Sbjct: 631 RNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKK 690
Query: 224 LTRARAILEKSRLKNPKNP 242
+A L K+ + +PKNP
Sbjct: 691 SEKALDTLNKAIVIDPKNP 709
>gi|167466175 cell division cycle protein 27 isoform 2 [Homo
sapiens]
Length = 824
Score = 33.5 bits (75), Expect = 0.35
Identities = 36/185 (19%), Positives = 76/185 (41%), Gaps = 3/185 (1%)
Query: 119 ENDEYERARRLLAKAR--SSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKL 176
E EY +A R+ ++ R + + + S L +Q ++ A L ++ ++ P+
Sbjct: 511 ELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDV-ALSVLSKDLTDMDKNSPEA 569
Query: 177 WMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQLTRARAILEKSRL 236
W G + + A + + + ++ P+ + LL +L +A A +
Sbjct: 570 WCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIR 629
Query: 237 KNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGILWSEAIFLEARPQRRTKSV 296
NP++ W + Y+ ++A KAL P S +L ++ ++ K++
Sbjct: 630 VNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKAL 689
Query: 297 DALKK 301
D L K
Sbjct: 690 DTLNK 694
Score = 32.0 bits (71), Expect = 1.0
Identities = 32/139 (23%), Positives = 55/139 (39%), Gaps = 1/139 (0%)
Query: 105 NSEEIWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSVKLEWV-QDNIRAAQDLC 163
NS E W AA S E++ A + +A P + E+V + + A
Sbjct: 565 NSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACF 624
Query: 164 EEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQ 223
A+R W G I ++E A + + L P S+ L + ++ + +
Sbjct: 625 RNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKK 684
Query: 224 LTRARAILEKSRLKNPKNP 242
+A L K+ + +PKNP
Sbjct: 685 SEKALDTLNKAIVIDPKNP 703
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 33.1 bits (74), Expect = 0.46
Identities = 29/161 (18%), Positives = 68/161 (42%), Gaps = 14/161 (8%)
Query: 49 EKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEE 108
E+ RE E + ++ + E +W K +W +P + L + E+
Sbjct: 396 EREKKMREEEETMREQEEKMQKQEENMWEQEEK-EWQQQRLPEQKEKLWEQEKMQEQEEK 454
Query: 109 IWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSVKLE------WVQDNIRAAQDL 162
IW K+ + + + + +++ + + +++ + K+ W Q+ QD
Sbjct: 455 IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQD- 513
Query: 163 CEEALRHYEDF----PKLWMMKGQIEEQKEMMEKAREAYNQ 199
E LR E+ K+W + ++ E+K+ E+ ++ ++Q
Sbjct: 514 --ERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQ 552
Score = 30.4 bits (67), Expect = 3.0
Identities = 19/100 (19%), Positives = 42/100 (42%), Gaps = 7/100 (7%)
Query: 107 EEIWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSVK-------LEWVQDNIRAA 159
E++W K++ E ER +++ + + K + EW Q +
Sbjct: 379 EKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 438
Query: 160 QDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQ 199
++ E + E K+W + +I +Q+EM + ++ + Q
Sbjct: 439 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ 478
>gi|7019491 DNA-directed DNA polymerase lambda [Homo sapiens]
Length = 575
Score = 32.7 bits (73), Expect = 0.60
Identities = 18/60 (30%), Positives = 32/60 (53%), Gaps = 10/60 (16%)
Query: 151 WVQDNIRAAQDLCEEA---------LRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGL 201
W Q R+ +D+ +A L+HY DF + M + + E ++ ++KA +A+N GL
Sbjct: 352 WYQQGFRSLEDIRSQASLTTQQAIGLKHYSDFLER-MPREEATEIEQTVQKAAQAFNSGL 410
>gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2
[Homo sapiens]
Length = 1235
Score = 32.3 bits (72), Expect = 0.79
Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Query: 107 EEIWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEA 166
EEI +E E + +R + L + R T ++ KL+W Q + L E
Sbjct: 356 EEILHKKRDIELEASQLDRYKELKEQVRKKVATMTQQLE--KLQWEQKTDE--ERLAFEK 411
Query: 167 LRHYEDFPKLWMMKGQIEEQKEMMEKARE 195
RH E L +K QIE+ K+ +EK E
Sbjct: 412 RRHGEVQGNLKQIKEQIEDHKKRIEKLEE 440
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.131 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,059,637
Number of Sequences: 37866
Number of extensions: 605460
Number of successful extensions: 2330
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 55
Number of HSP's that attempted gapping in prelim test: 2080
Number of HSP's gapped (non-prelim): 222
length of query: 406
length of database: 18,247,518
effective HSP length: 105
effective length of query: 301
effective length of database: 14,271,588
effective search space: 4295747988
effective search space used: 4295747988
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.