Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 166235901

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|166235901 B-cell linker isoform 2 [Homo sapiens]
         (433 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|166235901 B-cell linker isoform 2 [Homo sapiens]                   890   0.0  
gi|7019535 B-cell linker isoform 1 [Homo sapiens]                     877   0.0  
gi|5031855 lymphocyte cytosolic protein 2 [Homo sapiens]              127   3e-29
gi|193083221 mast cell immunoreceptor signal transducer [Homo sa...   111   1e-24
gi|38348280 SH2 domain containing 6 [Homo sapiens]                    104   2e-22
gi|110349719 titin isoform N2-A [Homo sapiens]                         53   6e-07
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    50   5e-06
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   49   1e-05
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   49   1e-05
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   49   1e-05
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    49   1e-05
gi|55741677 SET domain containing 1A [Homo sapiens]                    49   1e-05
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho...    48   2e-05
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho...    48   2e-05
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho...    48   2e-05
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom...    48   2e-05
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo...    48   2e-05
gi|237757326 synaptojanin 1 isoform d [Homo sapiens]                   47   4e-05
gi|189181750 human immunodeficiency virus type I enhancer bindin...    47   4e-05
gi|116089331 human immunodeficiency virus type I enhancer bindin...    47   4e-05
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    46   6e-05
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    46   6e-05
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    46   6e-05
gi|130977759 tec protein tyrosine kinase [Homo sapiens]                45   1e-04
gi|148596974 TXK tyrosine kinase [Homo sapiens]                        45   1e-04
gi|31324577 molecule interacting with Rab13 [Homo sapiens]             45   1e-04
gi|38787970 tensin like C1 domain containing phosphatase isoform...    45   2e-04
gi|38787957 tensin like C1 domain containing phosphatase isoform...    45   2e-04
gi|38787941 tensin like C1 domain containing phosphatase isoform...    45   2e-04
gi|4506431 RAS p21 protein activator 1 isoform 1 [Homo sapiens]        45   2e-04

>gi|166235901 B-cell linker isoform 2 [Homo sapiens]
          Length = 433

 Score =  890 bits (2299), Expect = 0.0
 Identities = 433/433 (100%), Positives = 433/433 (100%)

Query: 1   MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADE 60
           MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADE
Sbjct: 1   MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADE 60

Query: 61  EEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYI 120
           EEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYI
Sbjct: 61  EEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYI 120

Query: 121 DNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVV 180
           DNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVV
Sbjct: 121 DNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVV 180

Query: 181 PVEDNDENYIHPTESSSPPPEKGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVAS 240
           PVEDNDENYIHPTESSSPPPEKGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVAS
Sbjct: 181 PVEDNDENYIHPTESSSPPPEKGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVAS 240

Query: 241 QQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDG 300
           QQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDG
Sbjct: 241 QQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDG 300

Query: 301 PLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPY 360
           PLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPY
Sbjct: 301 PLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPY 360

Query: 361 TLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFGSVAEIIRNHQHSPLVLIDSQNNT 420
           TLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFGSVAEIIRNHQHSPLVLIDSQNNT
Sbjct: 361 TLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFGSVAEIIRNHQHSPLVLIDSQNNT 420

Query: 421 KDSTRLKYAVKVS 433
           KDSTRLKYAVKVS
Sbjct: 421 KDSTRLKYAVKVS 433


>gi|7019535 B-cell linker isoform 1 [Homo sapiens]
          Length = 456

 Score =  877 bits (2265), Expect = 0.0
 Identities = 433/456 (94%), Positives = 433/456 (94%), Gaps = 23/456 (5%)

Query: 1   MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADE 60
           MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADE
Sbjct: 1   MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADE 60

Query: 61  EEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYI 120
           EEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYI
Sbjct: 61  EEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYI 120

Query: 121 DNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVV 180
           DNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVV
Sbjct: 121 DNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVV 180

Query: 181 PVEDNDENYIHPTESSSPPPEK-----------------------GRNSGAWETKSPPPA 217
           PVEDNDENYIHPTESSSPPPEK                       GRNSGAWETKSPPPA
Sbjct: 181 PVEDNDENYIHPTESSSPPPEKAPMVNRSTKPNSSTPASPPGTASGRNSGAWETKSPPPA 240

Query: 218 APSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQ 277
           APSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQ
Sbjct: 241 APSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQ 300

Query: 278 KQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEAL 337
           KQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEAL
Sbjct: 301 KQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEAL 360

Query: 338 HRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFG 397
           HRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFG
Sbjct: 361 HRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFG 420

Query: 398 SVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAVKVS 433
           SVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAVKVS
Sbjct: 421 SVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAVKVS 456


>gi|5031855 lymphocyte cytosolic protein 2 [Homo sapiens]
          Length = 533

 Score =  127 bits (318), Expect = 3e-29
 Identities = 132/502 (26%), Positives = 186/502 (37%), Gaps = 122/502 (24%)

Query: 1   MDKLNKITVPASQKLRQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADE 60
           + K  K+ VP   KL Q      +I  NE       ++      P VPR    +ES  ++
Sbjct: 54  IQKFPKLRVPILSKLSQ------EINKNEE------RRSIFTRKPQVPRFPEETESHEED 101

Query: 61  EEQWSDDFDSDYENPDEHSDSEM---YVMPAEENA-----DDSYEPPPVEQET---RPVH 109
              WS   + DYE+P++  D E    Y  P EE       D  YEPPP   E      + 
Sbjct: 102 NGGWSSFEEDDYESPNDDQDGEDDGDYESPNEEEEAPVEDDADYEPPPSNDEEALQNSIL 161

Query: 110 PALPFARGE--YIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPK 167
           PA PF      YID        PP  KT P +P  P ++       P       P  PP+
Sbjct: 162 PAKPFPNSNSMYIDR-------PPSGKT-PQQPPVPPQRPMAALPPPPAGRNHSPLPPPQ 213

Query: 168 PK----GLLEDEADYVVPVEDNDENYIHPTESSSPPPEK-------------------GR 204
                     +     +P    D +   P + S  P ++                   GR
Sbjct: 214 TNHEEPSRSRNHKTAKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGR 273

Query: 205 NSGAWETKSPPPAAP---------SPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIP- 254
           + G    K   P  P         SPLP  GKKP  P        ++N      ++P+P 
Sbjct: 274 SLGEHLPKIQKPPLPPTTERHERSSPLP--GKKPPVPKHGWGPDRRENDEDDVHQRPLPQ 331

Query: 255 -------------------------------AERHRGSSHRQEAVQSPVF-------PPA 276
                                          A     SS  Q A   P F       PP 
Sbjct: 332 PALLPMSSNTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPI 391

Query: 277 QKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEA 336
           + +    P+PLP      +P                 +E   L + WY     R  AE A
Sbjct: 392 RAEGRNFPLPLPNKPRPPSPA----------------EEENSLNEEWYVSYITRPEAEAA 435

Query: 337 LHRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYF 396
           L + N+DG+FL+R SS   +  PY L+V +  +VYNI +R+ + ++ Y LG    G+E F
Sbjct: 436 LRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKESQVYLLGTGLRGKEDF 495

Query: 397 GSVAEIIRNHQHSPLVLIDSQN 418
            SV++II   +  PL+LID +N
Sbjct: 496 LSVSDIIDYFRKMPLLLIDGKN 517


>gi|193083221 mast cell immunoreceptor signal transducer [Homo
           sapiens]
          Length = 428

 Score =  111 bits (277), Expect = 1e-24
 Identities = 97/370 (26%), Positives = 154/370 (41%), Gaps = 61/370 (16%)

Query: 88  AEENADDSYEPPPVEQETR----PVHPALPFARGEYIDNR----SSQRHSPPFSKTLPS- 138
           A+ ++DD Y+ P +  E       + PA P    EY D      +     P  ++T  S 
Sbjct: 61  AKGHSDDDYDDPELRMEETWQSIKILPARPIKESEYADTHYFKVAMDTPLPLDTRTSISI 120

Query: 139 -KPSW-----------PSEKARLTSTLPALTALQKPQVP-PKPKGLLEDEADYVVPVEDN 185
            +P+W           P  K   +  +    +++K ++P P P+ L+     Y       
Sbjct: 121 GQPTWNTQTRLERVDKPISKDVRSQNIKGDASVRKNKIPLPPPRPLITLPKKY------- 173

Query: 186 DENYIHPTESSSPPPEKGRNSGAWETKSPPPAAPSPLPR---AGKKPTTPLK--TTPVAS 240
               + P   SS PP   R++     + P   +   L     A K P    K  +T +  
Sbjct: 174 --QPLPPEPESSRPPLSQRHTFPEVQRMPSQISLRDLSEVLEAEKVPHNQRKPESTHLLE 231

Query: 241 QQNASSV----------CEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRF 290
            QN   +               +    HRG    Q        PPA    H+  +P  ++
Sbjct: 232 NQNTQEIPLAISSSSFTTSNHSVQNRDHRGGM--QPCSPQRCQPPASCSPHENILPY-KY 288

Query: 291 TEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRK 350
           T    P      P  S    +   E       WY G   R++ EEA  + NKDGSFL+R 
Sbjct: 289 TSWRPP-----FPKRSDRKDVQHNE-------WYIGEYSRQAVEEAFMKENKDGSFLVRD 336

Query: 351 SSGHDSKQPYTLVVFFNKRVYNIPVRFIEATKQYALGRKKNGEEYFGSVAEIIRNHQHSP 410
            S    ++PY L VF+  +VYN+ +RF+E  +Q+ALG    G+E F SV +II ++++ P
Sbjct: 337 CSTKSKEEPYVLAVFYENKVYNVKIRFLERNQQFALGTGLRGDEKFDSVEDIIEHYKNFP 396

Query: 411 LVLIDSQNNT 420
           ++LID ++ T
Sbjct: 397 IILIDGKDKT 406


>gi|38348280 SH2 domain containing 6 [Homo sapiens]
          Length = 175

 Score =  104 bits (259), Expect = 2e-22
 Identities = 52/132 (39%), Positives = 83/132 (62%), Gaps = 2/132 (1%)

Query: 302 LPSFS-SNSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPY 360
           LPS + + S  + +++ +L +PWY+G CDR + E AL    KDG++ +R SSG    QP+
Sbjct: 43  LPSVAPTGSASAAEDSDLLTQPWYSGNCDRYAVESALLHLQKDGAYTVRPSSGPHGSQPF 102

Query: 361 TLVVFFNKRVYNIPVRFIEATKQYALGRK-KNGEEYFGSVAEIIRNHQHSPLVLIDSQNN 419
           TL V    RV+NIP+R ++  + YALGR+ +N EE F SVA ++++    PL L+D  + 
Sbjct: 103 TLAVLLRGRVFNIPIRRLDGGRHYALGREGRNREELFSSVAAMVQHFMWHPLPLVDRHSG 162

Query: 420 TKDSTRLKYAVK 431
           +++ T L +  K
Sbjct: 163 SRELTCLLFPTK 174


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 67/300 (22%), Positives = 112/300 (37%), Gaps = 25/300 (8%)

Query: 6     KITVPASQKLRQLQKMVHDIKNN---EGGIMNKIKKLKVKAPPSVPRRDYASESPADEEE 62
             K+ VPA +K+      V ++      E      + K     PP VP++      P    +
Sbjct: 10044 KVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQ 10103

Query: 63    QWSDDFDSDYENPDEHSDSEMYVMPAEENA-DDSYEPPPVEQETRPVHPALPFARGEYID 121
             +    F+ +    +E    E  V+P EE    +  E  P E+E  P    +P    EY+ 
Sbjct: 10104 EEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVP-PEEEYVP 10162

Query: 122   NRSS----QRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQK------PQVPPK--PK 169
                     +   P     +P     P  K ++T     +   ++      P+VP K   K
Sbjct: 10163 EEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEK 10222

Query: 170   GLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGRNSGAWETKSPPPAAPSPLPRAGKKP 229
              ++  + + V+PVE  +E    P      P E        E    PP  P  + +A    
Sbjct: 10223 RIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVA--PPRVPEVIKKA---- 10276

Query: 230   TTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLPR 289
               P   TPV  +  A      K IP E+      ++EA  + V P   K++ +K + +P+
Sbjct: 10277 -VPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKV-PEVPKKVPEKKVLVPK 10334



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 65/283 (22%), Positives = 104/283 (36%), Gaps = 70/283 (24%)

Query: 48   PRRDYAS---ESPADEEEQWSDDFDSD---YENPDEHSDSEM----------YVMPAEEN 91
            P  DY     E+  +  E+W +DF+     YE  + + + E            +   +E 
Sbjct: 9097 PDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEV 9156

Query: 92   ADDSYE------------PPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTL-PS 138
             ++S+E            PPP +   +PV   +        + +      P  SK + P 
Sbjct: 9157 YEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQ 9216

Query: 139  KPS-WPSEKARLTSTLPALTALQKPQVPPKPKGLL----EDEADYVVPVEDND---ENYI 190
            KPS  P ++  +   +PA+    K  V  + K       E+E    VP    +   E  I
Sbjct: 9217 KPSRTPVQEEVIEVKVPAVHT--KKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKI 9274

Query: 191  HPTESS--SPPPEKGRNSGAWETKSPPPAAPSPLPR-----AGKKPTTPLKTTPVASQQN 243
            H   S    PPP+        E  +P   AP P+P+     A K P  P K  P      
Sbjct: 9275 HVAISKRVEPPPKVPELP---EKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPE----- 9326

Query: 244  ASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIP 286
                 E+KP+P  +           + P  PP   ++ +KP+P
Sbjct: 9327 -----EKKPVPVPK-----------KEPAAPPKVPEVPKKPVP 9353



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 52/240 (21%), Positives = 92/240 (38%), Gaps = 37/240 (15%)

Query: 50   RDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVH 109
            +++    P +E +Q+ +  + +YE  +EH   E Y+   E+         PV +E  P  
Sbjct: 9754 KEFEEYEPTEEYDQYEEYEEREYERYEEH---EEYITEPEK----PIPVKPVPEEPVPTK 9806

Query: 110  PALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPK 169
            P  P A+                      K + P EK  +   +P       P+VP +PK
Sbjct: 9807 PKAPPAK--------------------VLKKAVPEEKVPV--PIPKKLKPPPPKVPEEPK 9844

Query: 170  GLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGRNSGAWETKSPPPAAPSPLPRAGKKP 229
             + E++    +   + ++     TE ++  P K +   A E    P    +P  R  + P
Sbjct: 9845 KVFEEKIRISITKREKEQ----VTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVP 9900

Query: 230  TTPLKTTPVASQQNASSVCEEKPIPAER---HRGSSHRQEAVQSPVFPPAQKQIHQKPIP 286
               L+   VA ++   +  EE  +  E    H       E    PV P    ++ +KP+P
Sbjct: 9901 -KELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVP 9959



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 59/249 (23%), Positives = 95/249 (38%), Gaps = 49/249 (19%)

Query: 45    PSVPRRDYASESPADEEEQWSDDFDSD-YENPDEHSDSEMYVMPAEENADDSYEPPPVEQ 103
             P VP++    E PA    + ++    + YE P+E       + P EE A +  +P PV +
Sbjct: 10776 PEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEE-------IAPEEEIAPEEEKPVPVAE 10828

Query: 104   ETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQ 163
             E  P  P                   PP     P K   P +K         +  ++KP+
Sbjct: 10829 EEEPEVP-------------------PPAVPEEPKK-IIPEKK---------VPVIKKPE 10859

Query: 164   VPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGRNSGAWETKSPPPAAPSPLP 223
              PP PK   E E + V+   +  +    P      PP++      ++ K+ P       P
Sbjct: 10860 APP-PK---EPEPEKVI---EKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKP 10912

Query: 224   RAGKK-PTTPLKTTPVASQQNASSVCEEKPIPAERHRGSS---HRQEAVQSPVFPPAQKQ 279
             +  +K   TPLK  P   ++    + E KP P E     S    R E  +  V P   ++
Sbjct: 10913 QVPEKVELTPLK-VPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEK 10971

Query: 280   IHQKPIPLP 288
             + +  +P P
Sbjct: 10972 VKKPAVPEP 10980



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 42/184 (22%), Positives = 71/184 (38%), Gaps = 21/184 (11%)

Query: 89   EENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSS-------QRHSPPFSKTLPSKPS 141
            E+ A +   P P+ ++  P  P +P    + +            +  +PP    +P KP 
Sbjct: 9293 EKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPV 9352

Query: 142  WPSEKARLTSTLPALTALQKP--QVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPP 199
             P EK      +P     + P  +VP   KG++ +E   +V   +       P       
Sbjct: 9353 -PEEKI----PVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKV 9407

Query: 200  PEKGRNSGAWETKSPPPAAPSPLPR---AGKKPTTPL----KTTPVASQQNASSVCEEKP 252
            PE+ +     E + PPP     LP+     +K   P+    K  P  ++ +  +V EEK 
Sbjct: 9408 PEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKR 9467

Query: 253  IPAE 256
              AE
Sbjct: 9468 FVAE 9471



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 45/184 (24%), Positives = 68/184 (36%), Gaps = 31/184 (16%)

Query: 134   KTLPSKPSWPSEKARLTSTLPALTALQKPQVPPK--PKGLLEDEADYVVPVEDNDENYIH 191
             + LP K   P +K  +    PA    +KP+ PP   P+   E   +  VPV    +  + 
Sbjct: 10497 EVLPPKEVVPEKKVPVP---PA----KKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVP 10549

Query: 192   PTESSSPPPEKGRNSGAWETKSPPPAAPSP-LPRAGKK-------PTTPLK---TTPVAS 240
             PT+    P          E   P P +P P +P A K+       P  P K    TPV  
Sbjct: 10550 PTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKV 10609

Query: 241   QQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQ-KQIHQKPIPLPRFTEGGNPTVD 299
              +    V  EK +P              + P  PP +  ++ +  +P  +  E   P  +
Sbjct: 10610 PEAPKEVVPEKKVPV----------PPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPE 10659

Query: 300   GPLP 303
              P P
Sbjct: 10660 SPPP 10663



 Score = 34.3 bits (77), Expect = 0.23
 Identities = 51/231 (22%), Positives = 83/231 (35%), Gaps = 20/231 (8%)

Query: 97    EPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSK-PSWPSEKARLTSTLPA 155
             E  P + E+ P  P +P A  E +  +      P   +  P K P  P E   +      
Sbjct: 10568 EAIPPKPESPP--PEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEV--VPEKKVP 10623

Query: 156   LTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGRNSGAWETKSPP 215
             +   +KP+VPP     + +     VP +   E    P +  SPPPE          + PP
Sbjct: 10624 VPPPKKPEVPPTK---VPEVPKVAVPEKKVPEAI--PPKPESPPPEVFEEPEEVALEEPP 10678

Query: 216   --------PAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEA 267
                     PAAP  +    KKP    K   V +++      +   +P E           
Sbjct: 10679 AEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVV 10738

Query: 268   VQSPVFPPAQ-KQIHQKPIPLPRFTEGGNPTV-DGPLPSFSSNSTISEQEA 316
              + P  PPA+  ++ ++ +P  +      P V    +P       + E+ A
Sbjct: 10739 PKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPA 10789



 Score = 33.1 bits (74), Expect = 0.50
 Identities = 38/141 (26%), Positives = 48/141 (34%), Gaps = 25/141 (17%)

Query: 134   KTLPSKPSWPSEKARLTSTL-------------PALTALQKPQVP--PKPKGLLEDEADY 178
             K LP +   P E+  L S L               L  ++KP VP  P PK + E E   
Sbjct: 10934 KLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPT 10993

Query: 179   VVP-----VEDNDENYIHPTESSSPPPEKGRNSGAWETKSPPPAAPSPLPRAGKKPTTPL 233
             V        E      I P      P  K +     +T  PPP  P P P A      P+
Sbjct: 10994 VTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIA-----APV 11048

Query: 234   KTTPVASQQNASSVCEEKPIP 254
                 V  +  A +  EE   P
Sbjct: 11049 TVPVVGKKAEAKAPKEEAAKP 11069



 Score = 29.3 bits (64), Expect = 7.3
 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 9/73 (12%)

Query: 266 EAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYA 325
           ++V++P   P++ ++  +P PLP+F     P  D P    S      ++E GV       
Sbjct: 857 KSVKAPTVKPSETRVRAEPTPLPQF-----PFADTPDTYKSEAGVEVKKEVGVS----IT 907

Query: 326 GACDRKSAEEALH 338
           G   R+   E LH
Sbjct: 908 GTTVREERFEVLH 920


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 46/168 (27%), Positives = 67/168 (39%), Gaps = 18/168 (10%)

Query: 110 PALPFARGEYIDNRSSQRHSPPFSKTLPSKPS--WPSEKARLTSTLPALTALQKPQVPPK 167
           PA P AR     + S+     P SK  PS PS  W    +   S  P  T    P  PP 
Sbjct: 444 PASPRARL----SASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTL---PPKPPS 496

Query: 168 PKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGRNSGAWETKSPPPAAPSPLPRAGK 227
           P+G        V   E+  E+   P+ +      + +   + E +S  PA+P+P P    
Sbjct: 497 PRGTTASPKGRVRRKEEAKES---PSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSP 553

Query: 228 KPTTPLKTTPVASQQNASSVCEEKPIPA------ERHRGSSHRQEAVQ 269
            P  P K  P A     ++V    P PA      +   G++ R+EA +
Sbjct: 554 TPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATR 601



 Score = 35.4 bits (80), Expect = 0.10
 Identities = 53/237 (22%), Positives = 84/237 (35%), Gaps = 19/237 (8%)

Query: 43  APPSVPRRDYASESPADEEEQWSDDFDSDYENPD---EHSDSEMYVMPAEENADDSYEPP 99
           +P  V RR  AS  P  ++E+   + +++ E      E S  +   +PA   A  S    
Sbjct: 399 SPAPVRRRPEAS--PVQKKEKKDKERENEKEKSALARERSLKKRQSLPASPRARLSAS-- 454

Query: 100 PVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTAL 159
               E  P   A P +        +S   SP    TLP KP  P    R T+  P     
Sbjct: 455 -TASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSP----RGTTASPKGRVR 509

Query: 160 QKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGRNSGAWETKSPPPAAP 219
           +K +    P     ++         N++    P  S +P P         + + PP   P
Sbjct: 510 RKEEAKESPSAAGPEDKSQSKRRASNEKESAAPA-SPAPSPAPSPTPAPPQKEQPPAETP 568

Query: 220 SPL-----PRAGKKPTTPLK-TTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQS 270
           +       P A   P TP K       ++ A+ +  EK   A   R    ++  +Q+
Sbjct: 569 TDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQA 625



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 33/132 (25%), Positives = 59/132 (44%), Gaps = 8/132 (6%)

Query: 137 PSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVE-DNDENYIHPTES 195
           P +P  PS +   +   P ++AL     P  P  +    +   +P+E ++    + P  +
Sbjct: 22  PPEPR-PSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPESPSGQVGPRPA 80

Query: 196 SSPPPEKGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPA 255
             PP E+  +S   E KS  P  P+  PR  + P    + +P A   + S   +++   A
Sbjct: 81  --PPQEESPSS---EAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVKKA 135

Query: 256 -ERHRGSSHRQE 266
            ERH+ +  R+E
Sbjct: 136 GERHKLAKERRE 147


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 50/204 (24%), Positives = 78/204 (38%), Gaps = 14/204 (6%)

Query: 87  PAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEK 146
           P E     + EP P   ++ P  P  P          ++ +   P +   P+ P+ P E 
Sbjct: 275 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT-PTTPKEP 333

Query: 147 ARLTSTLPALTALQKPQ--VPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGR 204
           A  T   PA T  ++P    P KP      E     P E        PT +  P P   +
Sbjct: 334 APTTKE-PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA------PTTTKEPSPTTPK 386

Query: 205 NSGAWETKSPPPAAPSPLPRAGKK-PTTPLKTTPVASQQNASSVCEE-KPIPAERHRGSS 262
                 TKS P     P P   K  PTTP + +P  +++ A +  +E  P   ++   ++
Sbjct: 387 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 446

Query: 263 HRQEAVQSPVFPPAQKQIHQKPIP 286
            ++ A  +P  P       +KP P
Sbjct: 447 PKEPAPTTPKEPAPTTT--KKPAP 468



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 54/297 (18%), Positives = 94/297 (31%), Gaps = 24/297 (8%)

Query: 43  APPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVE 102
           A P  PR      S   +E   + + ++  E  +  + ++      +E    + E   +E
Sbjct: 121 AKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIE 180

Query: 103 QETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKP 162
           + +            +      +    P  +      P+ P E A  T   P  T ++  
Sbjct: 181 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 240

Query: 163 QVPPKPKGLLEDEADYVVPVEDNDENYIHP--TESSSPPPEKGRNSGAWETKSPPPAAPS 220
              PK       ++    P E        P  T    P P   +      TKS P     
Sbjct: 241 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 300

Query: 221 PLPRAGKKP----------TTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQS 270
           P P   KKP          TTP + TP   ++ A +  E  P   +    ++ ++ A  +
Sbjct: 301 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 360

Query: 271 PVFPPAQKQIHQKPI------------PLPRFTEGGNPTVDGPLPSFSSNSTISEQE 315
           P  P         P             P P  T+    T   P P+ + ++  + +E
Sbjct: 361 PKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 417



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 48/223 (21%), Positives = 75/223 (33%), Gaps = 21/223 (9%)

Query: 97  EPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPAL 156
           EP P   ++ P  P  P          ++ +   P +   P+ P+ P E A  T   PA 
Sbjct: 402 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA-PTTPKEPAPTTPKEPAP 460

Query: 157 TALQKPQ---------------VPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPE 201
           T  +KP                 P  PK L     + + P          P E +   PE
Sbjct: 461 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE 520

Query: 202 KGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGS 261
           +   +   E     P A +P       PTTP +  P   ++ A +  +E      +    
Sbjct: 521 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP 580

Query: 262 SHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPS 304
           +  +E   +    PA K++       P  T     T D P P+
Sbjct: 581 TTLKEPAPTTPKKPAPKELAPTTTKEPTST-----TCDKPAPT 618



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 37/142 (26%), Positives = 53/142 (37%), Gaps = 14/142 (9%)

Query: 135 TLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTE 194
           T P KP+ P E A  T+  P  T   KP  P  PKG          P E        PT 
Sbjct: 589 TTPKKPA-PKELAPTTTKEPTSTTCDKP-APTTPKGTAP-----TTPKEPA------PTT 635

Query: 195 SSSPPPEKGRNSGAWETKSPPPAAP-SPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPI 253
              P P   + +     K P P  P  P P+     TT   T+  + +   ++  E  P 
Sbjct: 636 PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 695

Query: 254 PAERHRGSSHRQEAVQSPVFPP 275
             +    ++ ++ A  +P  PP
Sbjct: 696 TPKEPAPTTPKKPAPTTPETPP 717



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 36/132 (27%), Positives = 48/132 (36%), Gaps = 20/132 (15%)

Query: 135 TLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTE 194
           T P KP+ P E A  T+  P  T   KP  P  PK           P          PT 
Sbjct: 658 TTPKKPA-PKELAPTTTKGPTSTTSDKP-APTTPKETAPTTPKEPAPTTPKKPA---PTT 712

Query: 195 SSSPPPEKGRNSGAWETKSP-----------PPAAPSPLPRA----GKKPTTPLKTTPVA 239
             +PPP     S    TK P           P  +  P P+A     K+P  P   TP A
Sbjct: 713 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 772

Query: 240 SQQNASSVCEEK 251
           ++   ++  ++K
Sbjct: 773 TKPEMTTTAKDK 784



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 41/166 (24%), Positives = 62/166 (37%), Gaps = 19/166 (11%)

Query: 140 PSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPP 199
           P+ P E A  T   PA T  ++P  P  PK           P    +     PT    P 
Sbjct: 540 PNTPKEPAPTTPKEPAPTTPKEP-APTTPKETAPTTPKGTAPTTLKEPA---PTTPKKPA 595

Query: 200 PEKGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHR 259
           P++   +   E  S     P+P    G  PTTP +  P   ++ A       P   +   
Sbjct: 596 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA-------PTTPKGTA 648

Query: 260 GSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTV-DGPLPS 304
            ++ ++ A  +P   PA K++       P  T+G   T  D P P+
Sbjct: 649 PTTLKEPAPTTPK-KPAPKEL------APTTTKGPTSTTSDKPAPT 687



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 44/191 (23%), Positives = 62/191 (32%), Gaps = 13/191 (6%)

Query: 99  PPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTA 158
           P   +E  P  P  P A  E     + +  S    K  P+ P      A  T   PA T 
Sbjct: 580 PTTLKEPAPTTPKKP-APKELAPTTTKEPTSTTCDKPAPTTPKGT---APTTPKEPAPTT 635

Query: 159 LQKPQVPPKPKGLLEDEADYVVPVEDNDE--NYIHPTESSSPPPEKGRNSGAWETKSPPP 216
            ++P  P  PKG          P          + PT +  P             K   P
Sbjct: 636 PKEP-APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 694

Query: 217 AAPS-PLPRAGKKP--TTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVF 273
             P  P P   KKP  TTP    P  S+ +  +  +E   P   H+        + +   
Sbjct: 695 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE---PTTIHKSPDESTPELSAEPT 751

Query: 274 PPAQKQIHQKP 284
           P A +   ++P
Sbjct: 752 PKALENSPKEP 762


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 50/204 (24%), Positives = 78/204 (38%), Gaps = 14/204 (6%)

Query: 87  PAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEK 146
           P E     + EP P   ++ P  P  P          ++ +   P +   P+ P+ P E 
Sbjct: 316 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT-PTTPKEP 374

Query: 147 ARLTSTLPALTALQKPQ--VPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGR 204
           A  T   PA T  ++P    P KP      E     P E        PT +  P P   +
Sbjct: 375 APTTKE-PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA------PTTTKEPSPTTPK 427

Query: 205 NSGAWETKSPPPAAPSPLPRAGKK-PTTPLKTTPVASQQNASSVCEE-KPIPAERHRGSS 262
                 TKS P     P P   K  PTTP + +P  +++ A +  +E  P   ++   ++
Sbjct: 428 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 487

Query: 263 HRQEAVQSPVFPPAQKQIHQKPIP 286
            ++ A  +P  P       +KP P
Sbjct: 488 PKEPAPTTPKEPAPTTT--KKPAP 509



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 54/297 (18%), Positives = 94/297 (31%), Gaps = 24/297 (8%)

Query: 43  APPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVE 102
           A P  PR      S   +E   + + ++  E  +  + ++      +E    + E   +E
Sbjct: 162 AKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIE 221

Query: 103 QETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKP 162
           + +            +      +    P  +      P+ P E A  T   P  T ++  
Sbjct: 222 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 281

Query: 163 QVPPKPKGLLEDEADYVVPVEDNDENYIHP--TESSSPPPEKGRNSGAWETKSPPPAAPS 220
              PK       ++    P E        P  T    P P   +      TKS P     
Sbjct: 282 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 341

Query: 221 PLPRAGKKP----------TTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQS 270
           P P   KKP          TTP + TP   ++ A +  E  P   +    ++ ++ A  +
Sbjct: 342 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 401

Query: 271 PVFPPAQKQIHQKPI------------PLPRFTEGGNPTVDGPLPSFSSNSTISEQE 315
           P  P         P             P P  T+    T   P P+ + ++  + +E
Sbjct: 402 PKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 458



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 48/223 (21%), Positives = 75/223 (33%), Gaps = 21/223 (9%)

Query: 97  EPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPAL 156
           EP P   ++ P  P  P          ++ +   P +   P+ P+ P E A  T   PA 
Sbjct: 443 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA-PTTPKEPAPTTPKEPAP 501

Query: 157 TALQKPQ---------------VPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPE 201
           T  +KP                 P  PK L     + + P          P E +   PE
Sbjct: 502 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE 561

Query: 202 KGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGS 261
           +   +   E     P A +P       PTTP +  P   ++ A +  +E      +    
Sbjct: 562 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP 621

Query: 262 SHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPS 304
           +  +E   +    PA K++       P  T     T D P P+
Sbjct: 622 TTLKEPAPTTPKKPAPKELAPTTTKEPTST-----TCDKPAPT 659



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 37/142 (26%), Positives = 53/142 (37%), Gaps = 14/142 (9%)

Query: 135 TLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTE 194
           T P KP+ P E A  T+  P  T   KP  P  PKG          P E        PT 
Sbjct: 630 TTPKKPA-PKELAPTTTKEPTSTTCDKP-APTTPKGTAP-----TTPKEPA------PTT 676

Query: 195 SSSPPPEKGRNSGAWETKSPPPAAP-SPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPI 253
              P P   + +     K P P  P  P P+     TT   T+  + +   ++  E  P 
Sbjct: 677 PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 736

Query: 254 PAERHRGSSHRQEAVQSPVFPP 275
             +    ++ ++ A  +P  PP
Sbjct: 737 TPKEPAPTTPKKPAPTTPETPP 758



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 36/132 (27%), Positives = 48/132 (36%), Gaps = 20/132 (15%)

Query: 135 TLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTE 194
           T P KP+ P E A  T+  P  T   KP  P  PK           P          PT 
Sbjct: 699 TTPKKPA-PKELAPTTTKGPTSTTSDKP-APTTPKETAPTTPKEPAPTTPKKPA---PTT 753

Query: 195 SSSPPPEKGRNSGAWETKSP-----------PPAAPSPLPRA----GKKPTTPLKTTPVA 239
             +PPP     S    TK P           P  +  P P+A     K+P  P   TP A
Sbjct: 754 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 813

Query: 240 SQQNASSVCEEK 251
           ++   ++  ++K
Sbjct: 814 TKPEMTTTAKDK 825



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 41/166 (24%), Positives = 62/166 (37%), Gaps = 19/166 (11%)

Query: 140 PSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPP 199
           P+ P E A  T   PA T  ++P  P  PK           P    +     PT    P 
Sbjct: 581 PNTPKEPAPTTPKEPAPTTPKEP-APTTPKETAPTTPKGTAPTTLKEPA---PTTPKKPA 636

Query: 200 PEKGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHR 259
           P++   +   E  S     P+P    G  PTTP +  P   ++ A       P   +   
Sbjct: 637 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA-------PTTPKGTA 689

Query: 260 GSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTV-DGPLPS 304
            ++ ++ A  +P   PA K++       P  T+G   T  D P P+
Sbjct: 690 PTTLKEPAPTTPK-KPAPKEL------APTTTKGPTSTTSDKPAPT 728



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 44/191 (23%), Positives = 62/191 (32%), Gaps = 13/191 (6%)

Query: 99  PPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTA 158
           P   +E  P  P  P A  E     + +  S    K  P+ P      A  T   PA T 
Sbjct: 621 PTTLKEPAPTTPKKP-APKELAPTTTKEPTSTTCDKPAPTTPKGT---APTTPKEPAPTT 676

Query: 159 LQKPQVPPKPKGLLEDEADYVVPVEDNDE--NYIHPTESSSPPPEKGRNSGAWETKSPPP 216
            ++P  P  PKG          P          + PT +  P             K   P
Sbjct: 677 PKEP-APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 735

Query: 217 AAPS-PLPRAGKKP--TTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVF 273
             P  P P   KKP  TTP    P  S+ +  +  +E   P   H+        + +   
Sbjct: 736 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE---PTTIHKSPDESTPELSAEPT 792

Query: 274 PPAQKQIHQKP 284
           P A +   ++P
Sbjct: 793 PKALENSPKEP 803


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 50/204 (24%), Positives = 78/204 (38%), Gaps = 14/204 (6%)

Query: 87  PAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEK 146
           P E     + EP P   ++ P  P  P          ++ +   P +   P+ P+ P E 
Sbjct: 368 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT-PTTPKEP 426

Query: 147 ARLTSTLPALTALQKPQ--VPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGR 204
           A  T   PA T  ++P    P KP      E     P E        PT +  P P   +
Sbjct: 427 APTTKE-PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA------PTTTKEPSPTTPK 479

Query: 205 NSGAWETKSPPPAAPSPLPRAGKK-PTTPLKTTPVASQQNASSVCEE-KPIPAERHRGSS 262
                 TKS P     P P   K  PTTP + +P  +++ A +  +E  P   ++   ++
Sbjct: 480 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 539

Query: 263 HRQEAVQSPVFPPAQKQIHQKPIP 286
            ++ A  +P  P       +KP P
Sbjct: 540 PKEPAPTTPKEPAPTTT--KKPAP 561



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 54/297 (18%), Positives = 94/297 (31%), Gaps = 24/297 (8%)

Query: 43  APPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVE 102
           A P  PR      S   +E   + + ++  E  +  + ++      +E    + E   +E
Sbjct: 214 AKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIE 273

Query: 103 QETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKP 162
           + +            +      +    P  +      P+ P E A  T   P  T ++  
Sbjct: 274 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 333

Query: 163 QVPPKPKGLLEDEADYVVPVEDNDENYIHP--TESSSPPPEKGRNSGAWETKSPPPAAPS 220
              PK       ++    P E        P  T    P P   +      TKS P     
Sbjct: 334 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 393

Query: 221 PLPRAGKKP----------TTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQS 270
           P P   KKP          TTP + TP   ++ A +  E  P   +    ++ ++ A  +
Sbjct: 394 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 453

Query: 271 PVFPPAQKQIHQKPI------------PLPRFTEGGNPTVDGPLPSFSSNSTISEQE 315
           P  P         P             P P  T+    T   P P+ + ++  + +E
Sbjct: 454 PKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 510



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 48/223 (21%), Positives = 75/223 (33%), Gaps = 21/223 (9%)

Query: 97  EPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPAL 156
           EP P   ++ P  P  P          ++ +   P +   P+ P+ P E A  T   PA 
Sbjct: 495 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA-PTTPKEPAPTTPKEPAP 553

Query: 157 TALQKPQ---------------VPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPE 201
           T  +KP                 P  PK L     + + P          P E +   PE
Sbjct: 554 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE 613

Query: 202 KGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGS 261
           +   +   E     P A +P       PTTP +  P   ++ A +  +E      +    
Sbjct: 614 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP 673

Query: 262 SHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPS 304
           +  +E   +    PA K++       P  T     T D P P+
Sbjct: 674 TTLKEPAPTTPKKPAPKELAPTTTKEPTST-----TCDKPAPT 711



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 37/142 (26%), Positives = 53/142 (37%), Gaps = 14/142 (9%)

Query: 135 TLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTE 194
           T P KP+ P E A  T+  P  T   KP  P  PKG          P E        PT 
Sbjct: 682 TTPKKPA-PKELAPTTTKEPTSTTCDKP-APTTPKGTAP-----TTPKEPA------PTT 728

Query: 195 SSSPPPEKGRNSGAWETKSPPPAAP-SPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPI 253
              P P   + +     K P P  P  P P+     TT   T+  + +   ++  E  P 
Sbjct: 729 PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 788

Query: 254 PAERHRGSSHRQEAVQSPVFPP 275
             +    ++ ++ A  +P  PP
Sbjct: 789 TPKEPAPTTPKKPAPTTPETPP 810



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 36/132 (27%), Positives = 48/132 (36%), Gaps = 20/132 (15%)

Query: 135 TLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTE 194
           T P KP+ P E A  T+  P  T   KP  P  PK           P          PT 
Sbjct: 751 TTPKKPA-PKELAPTTTKGPTSTTSDKP-APTTPKETAPTTPKEPAPTTPKKPA---PTT 805

Query: 195 SSSPPPEKGRNSGAWETKSP-----------PPAAPSPLPRA----GKKPTTPLKTTPVA 239
             +PPP     S    TK P           P  +  P P+A     K+P  P   TP A
Sbjct: 806 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 865

Query: 240 SQQNASSVCEEK 251
           ++   ++  ++K
Sbjct: 866 TKPEMTTTAKDK 877



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 41/166 (24%), Positives = 62/166 (37%), Gaps = 19/166 (11%)

Query: 140 PSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPP 199
           P+ P E A  T   PA T  ++P  P  PK           P    +     PT    P 
Sbjct: 633 PNTPKEPAPTTPKEPAPTTPKEP-APTTPKETAPTTPKGTAPTTLKEPA---PTTPKKPA 688

Query: 200 PEKGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHR 259
           P++   +   E  S     P+P    G  PTTP +  P   ++ A       P   +   
Sbjct: 689 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA-------PTTPKGTA 741

Query: 260 GSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTV-DGPLPS 304
            ++ ++ A  +P   PA K++       P  T+G   T  D P P+
Sbjct: 742 PTTLKEPAPTTPK-KPAPKEL------APTTTKGPTSTTSDKPAPT 780



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 44/191 (23%), Positives = 62/191 (32%), Gaps = 13/191 (6%)

Query: 99  PPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTA 158
           P   +E  P  P  P A  E     + +  S    K  P+ P      A  T   PA T 
Sbjct: 673 PTTLKEPAPTTPKKP-APKELAPTTTKEPTSTTCDKPAPTTPKGT---APTTPKEPAPTT 728

Query: 159 LQKPQVPPKPKGLLEDEADYVVPVEDNDE--NYIHPTESSSPPPEKGRNSGAWETKSPPP 216
            ++P  P  PKG          P          + PT +  P             K   P
Sbjct: 729 PKEP-APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 787

Query: 217 AAPS-PLPRAGKKP--TTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVF 273
             P  P P   KKP  TTP    P  S+ +  +  +E   P   H+        + +   
Sbjct: 788 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE---PTTIHKSPDESTPELSAEPT 844

Query: 274 PPAQKQIHQKP 284
           P A +   ++P
Sbjct: 845 PKALENSPKEP 855


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 50/204 (24%), Positives = 78/204 (38%), Gaps = 14/204 (6%)

Query: 87  PAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEK 146
           P E     + EP P   ++ P  P  P          ++ +   P +   P+ P+ P E 
Sbjct: 409 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT-PTTPKEP 467

Query: 147 ARLTSTLPALTALQKPQ--VPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGR 204
           A  T   PA T  ++P    P KP      E     P E        PT +  P P   +
Sbjct: 468 APTTKE-PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA------PTTTKEPSPTTPK 520

Query: 205 NSGAWETKSPPPAAPSPLPRAGKK-PTTPLKTTPVASQQNASSVCEE-KPIPAERHRGSS 262
                 TKS P     P P   K  PTTP + +P  +++ A +  +E  P   ++   ++
Sbjct: 521 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 580

Query: 263 HRQEAVQSPVFPPAQKQIHQKPIP 286
            ++ A  +P  P       +KP P
Sbjct: 581 PKEPAPTTPKEPAPTTT--KKPAP 602



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 54/297 (18%), Positives = 94/297 (31%), Gaps = 24/297 (8%)

Query: 43  APPSVPRRDYASESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVE 102
           A P  PR      S   +E   + + ++  E  +  + ++      +E    + E   +E
Sbjct: 255 AKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIE 314

Query: 103 QETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKP 162
           + +            +      +    P  +      P+ P E A  T   P  T ++  
Sbjct: 315 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 374

Query: 163 QVPPKPKGLLEDEADYVVPVEDNDENYIHP--TESSSPPPEKGRNSGAWETKSPPPAAPS 220
              PK       ++    P E        P  T    P P   +      TKS P     
Sbjct: 375 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 434

Query: 221 PLPRAGKKP----------TTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQS 270
           P P   KKP          TTP + TP   ++ A +  E  P   +    ++ ++ A  +
Sbjct: 435 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 494

Query: 271 PVFPPAQKQIHQKPI------------PLPRFTEGGNPTVDGPLPSFSSNSTISEQE 315
           P  P         P             P P  T+    T   P P+ + ++  + +E
Sbjct: 495 PKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 551



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 48/223 (21%), Positives = 75/223 (33%), Gaps = 21/223 (9%)

Query: 97  EPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPAL 156
           EP P   ++ P  P  P          ++ +   P +   P+ P+ P E A  T   PA 
Sbjct: 536 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA-PTTPKEPAPTTPKEPAP 594

Query: 157 TALQKPQ---------------VPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPE 201
           T  +KP                 P  PK L     + + P          P E +   PE
Sbjct: 595 TTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE 654

Query: 202 KGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGS 261
           +   +   E     P A +P       PTTP +  P   ++ A +  +E      +    
Sbjct: 655 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP 714

Query: 262 SHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPS 304
           +  +E   +    PA K++       P  T     T D P P+
Sbjct: 715 TTLKEPAPTTPKKPAPKELAPTTTKEPTST-----TCDKPAPT 752



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 37/142 (26%), Positives = 53/142 (37%), Gaps = 14/142 (9%)

Query: 135 TLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTE 194
           T P KP+ P E A  T+  P  T   KP  P  PKG          P E        PT 
Sbjct: 723 TTPKKPA-PKELAPTTTKEPTSTTCDKP-APTTPKGTAP-----TTPKEPA------PTT 769

Query: 195 SSSPPPEKGRNSGAWETKSPPPAAP-SPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPI 253
              P P   + +     K P P  P  P P+     TT   T+  + +   ++  E  P 
Sbjct: 770 PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 829

Query: 254 PAERHRGSSHRQEAVQSPVFPP 275
             +    ++ ++ A  +P  PP
Sbjct: 830 TPKEPAPTTPKKPAPTTPETPP 851



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 36/132 (27%), Positives = 48/132 (36%), Gaps = 20/132 (15%)

Query: 135 TLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTE 194
           T P KP+ P E A  T+  P  T   KP  P  PK           P          PT 
Sbjct: 792 TTPKKPA-PKELAPTTTKGPTSTTSDKP-APTTPKETAPTTPKEPAPTTPKKPA---PTT 846

Query: 195 SSSPPPEKGRNSGAWETKSP-----------PPAAPSPLPRA----GKKPTTPLKTTPVA 239
             +PPP     S    TK P           P  +  P P+A     K+P  P   TP A
Sbjct: 847 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 906

Query: 240 SQQNASSVCEEK 251
           ++   ++  ++K
Sbjct: 907 TKPEMTTTAKDK 918



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 41/166 (24%), Positives = 62/166 (37%), Gaps = 19/166 (11%)

Query: 140 PSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPP 199
           P+ P E A  T   PA T  ++P  P  PK           P    +     PT    P 
Sbjct: 674 PNTPKEPAPTTPKEPAPTTPKEP-APTTPKETAPTTPKGTAPTTLKEPA---PTTPKKPA 729

Query: 200 PEKGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHR 259
           P++   +   E  S     P+P    G  PTTP +  P   ++ A       P   +   
Sbjct: 730 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA-------PTTPKGTA 782

Query: 260 GSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTV-DGPLPS 304
            ++ ++ A  +P   PA K++       P  T+G   T  D P P+
Sbjct: 783 PTTLKEPAPTTPK-KPAPKEL------APTTTKGPTSTTSDKPAPT 821



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 44/191 (23%), Positives = 62/191 (32%), Gaps = 13/191 (6%)

Query: 99  PPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTA 158
           P   +E  P  P  P A  E     + +  S    K  P+ P      A  T   PA T 
Sbjct: 714 PTTLKEPAPTTPKKP-APKELAPTTTKEPTSTTCDKPAPTTPKGT---APTTPKEPAPTT 769

Query: 159 LQKPQVPPKPKGLLEDEADYVVPVEDNDE--NYIHPTESSSPPPEKGRNSGAWETKSPPP 216
            ++P  P  PKG          P          + PT +  P             K   P
Sbjct: 770 PKEP-APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 828

Query: 217 AAPS-PLPRAGKKP--TTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVF 273
             P  P P   KKP  TTP    P  S+ +  +  +E   P   H+        + +   
Sbjct: 829 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE---PTTIHKSPDESTPELSAEPT 885

Query: 274 PPAQKQIHQKP 284
           P A +   ++P
Sbjct: 886 PKALENSPKEP 896


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 57/241 (23%), Positives = 83/241 (34%), Gaps = 20/241 (8%)

Query: 54   SESPADEEEQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALP 113
            S S  DEE+   D+ D D E   + +  E  V   E+   DS     +  ++   + +  
Sbjct: 972  SSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTS 1031

Query: 114  FARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKP--QVP---PKP 168
             +      + SS   S   S +  S     SE         AL +   P  +VP   P P
Sbjct: 1032 DSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAP 1091

Query: 169  KGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGRNSGAWETKSPPPAAPSPLPRAGKK 228
              +   E     PV    E    P   + P  E+   S       PP   P+P PR  ++
Sbjct: 1092 VEVPVPERVAGSPVTPLPEQEASPARPAGPT-EESPPSAPLRPPEPPAGPPAPAPRPDER 1150

Query: 229  PTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIPLP 288
            P++P+   P              P    R   S    E V +P  PPA     + P P  
Sbjct: 1151 PSSPIPLLP--------------PPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFPGPAS 1196

Query: 289  R 289
            R
Sbjct: 1197 R 1197



 Score = 33.5 bits (75), Expect = 0.39
 Identities = 41/155 (26%), Positives = 61/155 (39%), Gaps = 23/155 (14%)

Query: 86   MPAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSE 145
            +PA    +DS      ++  RP  P L     E+ +   + + +PP     P +P  P+ 
Sbjct: 1268 LPALPAVEDSEATETSDEAERP-RPLLSHILLEH-NYALAVKPTPPAPALRPPEPV-PAP 1324

Query: 146  KARLTSTLPALTALQKPQV------PPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPP 199
             A  +S  PA   L+ P+V       PKP+ L +   +     E+ +E      E SS  
Sbjct: 1325 AALFSS--PADEVLEAPEVVVAEAEEPKPQQLQQQREE---GEEEGEEEGEEEEEESSDS 1379

Query: 200  PEKGRNSGAWETKS---------PPPAAPSPLPRA 225
                   GA   +S         PPP  P P PRA
Sbjct: 1380 SSSSDGEGALRRRSLRSHARRRRPPPPPPPPPPRA 1414



 Score = 29.6 bits (65), Expect = 5.6
 Identities = 30/124 (24%), Positives = 44/124 (35%), Gaps = 22/124 (17%)

Query: 126 QRHS--PPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVE 183
           QRH+  PP   T    P  P  +       P+ T+     +PP+P               
Sbjct: 377 QRHTSYPPRRATREEPPGAPFAENTAERFPPSYTSY----LPPEPS-------------R 419

Query: 184 DNDENYIHPTESSSPPPEKGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQN 243
             D++Y  P  S +PPPE     G      P P       R   +P +P ++   A +  
Sbjct: 420 PTDQDY-RPPASEAPPPEPPEPGGGGGGGGPSPEREE--VRTSPRPASPARSGSPAPETT 476

Query: 244 ASSV 247
             SV
Sbjct: 477 NESV 480


>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 55/202 (27%), Positives = 73/202 (36%), Gaps = 56/202 (27%)

Query: 81  SEMYVMPAEENADDSYEPPPVEQ-----ETRPVHPALPFARGEYIDNRSSQRHS------ 129
           SE+     E      +EPPP        + +P+   +  A G  I+NR     +      
Sbjct: 261 SELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATG-LIENRPQSPATGRTPVF 319

Query: 130 -----PPFSKTLPSKPSWPSEKARLTSTLPA---------LTALQKPQVPPKPKGLLEDE 175
                PP    LPS  S  S +A +TST P           TALQ P VPP P  L    
Sbjct: 320 VSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPL---- 375

Query: 176 ADYVVPVEDNDENYIHPTESS------SPPPEKGRNSGAWETKS------------PPPA 217
              + P        +HP           P P   R +   ET              PPP 
Sbjct: 376 --QIAP------GVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPP 427

Query: 218 APSPLPRAGKKPTTPLKTTPVA 239
            P PLP  G +P++P+  T +A
Sbjct: 428 PPPPLPPPGIRPSSPVTVTALA 449



 Score = 35.8 bits (81), Expect = 0.078
 Identities = 47/209 (22%), Positives = 65/209 (31%), Gaps = 47/209 (22%)

Query: 111 ALPFARGEYIDNRSSQR-----HSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVP 165
           ALPF++   +  R+ +R     H PP        P  P   A     +P   +     + 
Sbjct: 254 ALPFSQMSELLTRAEERVLVRPHEPP--------PPPPMHGAGDAKPIPTCISSATGLIE 305

Query: 166 PKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGRNSG----AWETKSPPPAAPSP 221
            +P+           P       ++ PT    PPP     S     A  T +PPP  P P
Sbjct: 306 NRPQS----------PATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPP 355

Query: 222 LPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIH 281
            P        P    P A  Q A  V    P P             +  P+  P+     
Sbjct: 356 PPPPATALQAPAVPPPPAPLQIAPGVLHPAPPP-------------IAPPLVQPSPPVAR 402

Query: 282 QKPI-------PLPRFTEGGNPTVDGPLP 303
             P+       PLP+    G P    P P
Sbjct: 403 AAPVCETVPVHPLPQGEVQGLPPPPPPPP 431



 Score = 34.3 bits (77), Expect = 0.23
 Identities = 37/156 (23%), Positives = 54/156 (34%), Gaps = 21/156 (13%)

Query: 87  PAEENADDSYEPPPVEQETRP--VHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPS 144
           PA      +  PPP   +  P  +HPA P      +        + P  +T+P  P    
Sbjct: 359 PATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQG 418

Query: 145 EKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGR 204
           E   L            P  PP P   +   +   V    +  + +HPT S++P P    
Sbjct: 419 EVQGLPPP---------PPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGP---- 465

Query: 205 NSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVAS 240
                     PP+ PS +  A +    P  T PV S
Sbjct: 466 -----HVPLMPPSPPSQVIPASEPKRHP-STLPVIS 495


>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 55/202 (27%), Positives = 73/202 (36%), Gaps = 56/202 (27%)

Query: 81  SEMYVMPAEENADDSYEPPPVEQ-----ETRPVHPALPFARGEYIDNRSSQRHS------ 129
           SE+     E      +EPPP        + +P+   +  A G  I+NR     +      
Sbjct: 261 SELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATG-LIENRPQSPATGRTPVF 319

Query: 130 -----PPFSKTLPSKPSWPSEKARLTSTLPA---------LTALQKPQVPPKPKGLLEDE 175
                PP    LPS  S  S +A +TST P           TALQ P VPP P  L    
Sbjct: 320 VSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPL---- 375

Query: 176 ADYVVPVEDNDENYIHPTESS------SPPPEKGRNSGAWETKS------------PPPA 217
              + P        +HP           P P   R +   ET              PPP 
Sbjct: 376 --QIAP------GVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPP 427

Query: 218 APSPLPRAGKKPTTPLKTTPVA 239
            P PLP  G +P++P+  T +A
Sbjct: 428 PPPPLPPPGIRPSSPVTVTALA 449



 Score = 35.8 bits (81), Expect = 0.078
 Identities = 47/209 (22%), Positives = 65/209 (31%), Gaps = 47/209 (22%)

Query: 111 ALPFARGEYIDNRSSQR-----HSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVP 165
           ALPF++   +  R+ +R     H PP        P  P   A     +P   +     + 
Sbjct: 254 ALPFSQMSELLTRAEERVLVRPHEPP--------PPPPMHGAGDAKPIPTCISSATGLIE 305

Query: 166 PKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGRNSG----AWETKSPPPAAPSP 221
            +P+           P       ++ PT    PPP     S     A  T +PPP  P P
Sbjct: 306 NRPQS----------PATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPP 355

Query: 222 LPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIH 281
            P        P    P A  Q A  V    P P             +  P+  P+     
Sbjct: 356 PPPPATALQAPAVPPPPAPLQIAPGVLHPAPPP-------------IAPPLVQPSPPVAR 402

Query: 282 QKPI-------PLPRFTEGGNPTVDGPLP 303
             P+       PLP+    G P    P P
Sbjct: 403 AAPVCETVPVHPLPQGEVQGLPPPPPPPP 431



 Score = 34.3 bits (77), Expect = 0.23
 Identities = 37/156 (23%), Positives = 54/156 (34%), Gaps = 21/156 (13%)

Query: 87  PAEENADDSYEPPPVEQETRP--VHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPS 144
           PA      +  PPP   +  P  +HPA P      +        + P  +T+P  P    
Sbjct: 359 PATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQG 418

Query: 145 EKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGR 204
           E   L            P  PP P   +   +   V    +  + +HPT S++P P    
Sbjct: 419 EVQGLPPP---------PPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGP---- 465

Query: 205 NSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVAS 240
                     PP+ PS +  A +    P  T PV S
Sbjct: 466 -----HVPLMPPSPPSQVIPASEPKRHP-STLPVIS 495


>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 55/202 (27%), Positives = 73/202 (36%), Gaps = 56/202 (27%)

Query: 81  SEMYVMPAEENADDSYEPPPVEQ-----ETRPVHPALPFARGEYIDNRSSQRHS------ 129
           SE+     E      +EPPP        + +P+   +  A G  I+NR     +      
Sbjct: 261 SELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATG-LIENRPQSPATGRTPVF 319

Query: 130 -----PPFSKTLPSKPSWPSEKARLTSTLPA---------LTALQKPQVPPKPKGLLEDE 175
                PP    LPS  S  S +A +TST P           TALQ P VPP P  L    
Sbjct: 320 VSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPL---- 375

Query: 176 ADYVVPVEDNDENYIHPTESS------SPPPEKGRNSGAWETKS------------PPPA 217
              + P        +HP           P P   R +   ET              PPP 
Sbjct: 376 --QIAP------GVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPP 427

Query: 218 APSPLPRAGKKPTTPLKTTPVA 239
            P PLP  G +P++P+  T +A
Sbjct: 428 PPPPLPPPGIRPSSPVTVTALA 449



 Score = 35.8 bits (81), Expect = 0.078
 Identities = 47/209 (22%), Positives = 65/209 (31%), Gaps = 47/209 (22%)

Query: 111 ALPFARGEYIDNRSSQR-----HSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVP 165
           ALPF++   +  R+ +R     H PP        P  P   A     +P   +     + 
Sbjct: 254 ALPFSQMSELLTRAEERVLVRPHEPP--------PPPPMHGAGDAKPIPTCISSATGLIE 305

Query: 166 PKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGRNSG----AWETKSPPPAAPSP 221
            +P+           P       ++ PT    PPP     S     A  T +PPP  P P
Sbjct: 306 NRPQS----------PATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPP 355

Query: 222 LPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIH 281
            P        P    P A  Q A  V    P P             +  P+  P+     
Sbjct: 356 PPPPATALQAPAVPPPPAPLQIAPGVLHPAPPP-------------IAPPLVQPSPPVAR 402

Query: 282 QKPI-------PLPRFTEGGNPTVDGPLP 303
             P+       PLP+    G P    P P
Sbjct: 403 AAPVCETVPVHPLPQGEVQGLPPPPPPPP 431



 Score = 34.3 bits (77), Expect = 0.23
 Identities = 37/156 (23%), Positives = 54/156 (34%), Gaps = 21/156 (13%)

Query: 87  PAEENADDSYEPPPVEQETRP--VHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPS 144
           PA      +  PPP   +  P  +HPA P      +        + P  +T+P  P    
Sbjct: 359 PATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQG 418

Query: 145 EKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGR 204
           E   L            P  PP P   +   +   V    +  + +HPT S++P P    
Sbjct: 419 EVQGLPPP---------PPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGP---- 465

Query: 205 NSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVAS 240
                     PP+ PS +  A +    P  T PV S
Sbjct: 466 -----HVPLMPPSPPSQVIPASEPKRHP-STLPVIS 495


>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 55/202 (27%), Positives = 73/202 (36%), Gaps = 56/202 (27%)

Query: 81  SEMYVMPAEENADDSYEPPPVEQ-----ETRPVHPALPFARGEYIDNRSSQRHS------ 129
           SE+     E      +EPPP        + +P+   +  A G  I+NR     +      
Sbjct: 261 SELLTRAEERVLVRPHEPPPPPPMHGAGDAKPIPTCISSATG-LIENRPQSPATGRTPVF 319

Query: 130 -----PPFSKTLPSKPSWPSEKARLTSTLPA---------LTALQKPQVPPKPKGLLEDE 175
                PP    LPS  S  S +A +TST P           TALQ P VPP P  L    
Sbjct: 320 VSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPL---- 375

Query: 176 ADYVVPVEDNDENYIHPTESS------SPPPEKGRNSGAWETKS------------PPPA 217
              + P        +HP           P P   R +   ET              PPP 
Sbjct: 376 --QIAP------GVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPP 427

Query: 218 APSPLPRAGKKPTTPLKTTPVA 239
            P PLP  G +P++P+  T +A
Sbjct: 428 PPPPLPPPGIRPSSPVTVTALA 449



 Score = 35.8 bits (81), Expect = 0.078
 Identities = 47/209 (22%), Positives = 65/209 (31%), Gaps = 47/209 (22%)

Query: 111 ALPFARGEYIDNRSSQR-----HSPPFSKTLPSKPSWPSEKARLTSTLPALTALQKPQVP 165
           ALPF++   +  R+ +R     H PP        P  P   A     +P   +     + 
Sbjct: 254 ALPFSQMSELLTRAEERVLVRPHEPP--------PPPPMHGAGDAKPIPTCISSATGLIE 305

Query: 166 PKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGRNSG----AWETKSPPPAAPSP 221
            +P+           P       ++ PT    PPP     S     A  T +PPP  P P
Sbjct: 306 NRPQS----------PATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPP 355

Query: 222 LPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIH 281
            P        P    P A  Q A  V    P P             +  P+  P+     
Sbjct: 356 PPPPATALQAPAVPPPPAPLQIAPGVLHPAPPP-------------IAPPLVQPSPPVAR 402

Query: 282 QKPI-------PLPRFTEGGNPTVDGPLP 303
             P+       PLP+    G P    P P
Sbjct: 403 AAPVCETVPVHPLPQGEVQGLPPPPPPPP 431



 Score = 34.3 bits (77), Expect = 0.23
 Identities = 37/156 (23%), Positives = 54/156 (34%), Gaps = 21/156 (13%)

Query: 87  PAEENADDSYEPPPVEQETRP--VHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPS 144
           PA      +  PPP   +  P  +HPA P      +        + P  +T+P  P    
Sbjct: 359 PATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQG 418

Query: 145 EKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGR 204
           E   L            P  PP P   +   +   V    +  + +HPT S++P P    
Sbjct: 419 EVQGLPPP---------PPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGP---- 465

Query: 205 NSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVAS 240
                     PP+ PS +  A +    P  T PV S
Sbjct: 466 -----HVPLMPPSPPSQVIPASEPKRHP-STLPVIS 495


>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
           sapiens]
          Length = 1158

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 59/224 (26%), Positives = 85/224 (37%), Gaps = 37/224 (16%)

Query: 56  SPADEE--EQWSDDFDSDYENPDEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALP 113
           SP  EE  ++      ++++NP E +  E     A E     ++P P E+ET    P L 
Sbjct: 188 SPGPEELPQEGGAPLSNNWQNPGEETHVE-----ARE-----HQPEP-EEETE--QPTLD 234

Query: 114 F----ARGEYID----NRSSQRHSPPFSKTLPSK--PSWPSEKARLTSTLPALTALQKPQ 163
           +     R +Y D     R  Q   PP  +  P +  P  P EKA   +    +    KP 
Sbjct: 235 YNDQIEREDYEDFEYIRRQKQPRPPPSRRRRPERVWPEPPEEKAPAPAPEERIEPPVKPL 294

Query: 164 VPPKPKGLLEDEAD-YVVPVEDNDENYIHPTESSSPPPEKGRNSGAWETKSPPPAAPSPL 222
           +PP P     D  D YV+P  D+ + Y  P     P  E+  +    E K P     SP 
Sbjct: 295 LPPLPP----DYGDGYVIPNYDDMDYYFGPPPPQKPDAERQTDEEKEELKKPKKEDSSPK 350

Query: 223 PRA-------GKKPTTPLKTTPVASQQNASSVCEEKPIPAERHR 259
                     GK    P K   +  +   +   +  PI  E HR
Sbjct: 351 EETDKWAVEKGKDHKEPRKGEELEEEWTPTEKVKCPPIGMESHR 394



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 31/109 (28%), Positives = 45/109 (41%), Gaps = 24/109 (22%)

Query: 194 ESSSPPPEKGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPI 253
           E S  PP+KG+       + PP A   P  +  K    P +  P A+++      +EKP 
Sbjct: 111 EGSPRPPKKGK-------EKPPKATKKPKEKPPKATKKPKEKPPKATKKP-----KEKPP 158

Query: 254 PAERHRGSSHR------QEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNP 296
            A +   S  R       E ++ P+ PP        P  LP+  EGG P
Sbjct: 159 KATKKPPSGKRPPILAPSETLEWPLPPPPS----PGPEELPQ--EGGAP 201



 Score = 28.9 bits (63), Expect = 9.5
 Identities = 38/148 (25%), Positives = 63/148 (42%), Gaps = 29/148 (19%)

Query: 147 ARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGRNS 206
           A L S L AL AL       +P+ +L D+      +E+  E ++   E   P P +    
Sbjct: 7   APLLSCLLALLALCPGG---RPQTVLTDDE-----IEEFLEGFLSELE---PEPRED--- 52

Query: 207 GAWETKSPPPAAPSPLPR-------AGKKPTTPLKTTPVASQQNASSVCEEK--PIPAER 257
              + ++PPP  P+P  R        GK+P T  +  P  ++       ++K   +P E 
Sbjct: 53  ---DVEAPPPPEPTPRVRKAQAGGKPGKRPGTAAEVPPEKTKDKGKKGKKDKGPKVPKES 109

Query: 258 HRGSSH-RQEAVQSPVFPPAQKQIHQKP 284
             GS    ++  + P  P A K+  +KP
Sbjct: 110 LEGSPRPPKKGKEKP--PKATKKPKEKP 135


>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
          Length = 1526

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 64/305 (20%), Positives = 111/305 (36%), Gaps = 54/305 (17%)

Query: 79   SDSEMYVMPAEENADDSYEPPPVEQETRPV--HPALPFARGEYIDNRSSQRHSPPFSKTL 136
            S+  +  +P   +   S  P P   ++ P+   PA P  + +       +R  PP     
Sbjct: 1052 SEGPVPSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAP 1111

Query: 137  PSKP------------SWPSEKARLTSTLPALTALQKPQVPPK------PKGLLEDEADY 178
            P++P            S PS +A L    PA  +  +P +PP+      P+      A  
Sbjct: 1112 PTRPAPPQRPPPPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGR 1171

Query: 179  VVPVEDNDENYIHPTESSSPPPEKGRNSGAWETKSPPPA---------APSPLPRAGKKP 229
            + P   +  +      +  P P K + +   ++  PPPA           +P+P++G +P
Sbjct: 1172 LTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQP 1231

Query: 230  T--TPLKTTPVASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFP------------P 275
               TP +  P  S+ + S   E    P  +  G S  +      + P             
Sbjct: 1232 NLETPPQPPP-RSRSSHSLPSEASSQPQVKTNGISDGKRESPLKIDPFEDLSFNLLAVSK 1290

Query: 276  AQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEE 335
            AQ  +   P+P P      +P     LPS + ++ +S     V C P       R  ++E
Sbjct: 1291 AQLSVQTSPVPTP------DPKRLIQLPSATQSNVLS----SVSCMPTMPPIPARSQSQE 1340

Query: 336  ALHRS 340
             +  S
Sbjct: 1341 NMRSS 1345


>gi|189181750 human immunodeficiency virus type I enhancer binding
            protein 3 b [Homo sapiens]
          Length = 2405

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 54/229 (23%), Positives = 92/229 (40%), Gaps = 17/229 (7%)

Query: 16   RQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFDSDYENP 75
            + ++   H  K  E G++ +++  +  +       +    S A EE Q+SD  DSD ++ 
Sbjct: 1799 KHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSD 1858

Query: 76   DEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFA-RGEYIDNRSSQRHSPPFSK 134
             +  + E      +E +  S E PP         P  P A R +       Q    P S 
Sbjct: 1859 LDEDEDEDEEESQDELSRPSSEAPP---------PGPPHALRADSSPILGPQPPDAPASG 1909

Query: 135  TLPSKPSWPSEKARLTSTLPALTALQKPQVP---PKPKGLLEDEADYVV---PVEDNDEN 188
            T  ++ S  SE  RLT++  ++++   P +P   P P G +E +    +   PV      
Sbjct: 1910 TEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPR-RP 1968

Query: 189  YIHPTESSSPPPEKGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTP 237
            +    E+ S PP   ++S      SP   +P+  P+A       L   P
Sbjct: 1969 WSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDP 2017


>gi|116089331 human immunodeficiency virus type I enhancer binding
            protein 3 [Homo sapiens]
          Length = 2406

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 54/229 (23%), Positives = 92/229 (40%), Gaps = 17/229 (7%)

Query: 16   RQLQKMVHDIKNNEGGIMNKIKKLKVKAPPSVPRRDYASESPADEEEQWSDDFDSDYENP 75
            + ++   H  K  E G++ +++  +  +       +    S A EE Q+SD  DSD ++ 
Sbjct: 1799 KHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSD 1858

Query: 76   DEHSDSEMYVMPAEENADDSYEPPPVEQETRPVHPALPFA-RGEYIDNRSSQRHSPPFSK 134
             +  + E      +E +  S E PP         P  P A R +       Q    P S 
Sbjct: 1859 LDEDEDEDEEESQDELSRPSSEAPP---------PGPPHALRADSSPILGPQPPDAPASG 1909

Query: 135  TLPSKPSWPSEKARLTSTLPALTALQKPQVP---PKPKGLLEDEADYVV---PVEDNDEN 188
            T  ++ S  SE  RLT++  ++++   P +P   P P G +E +    +   PV      
Sbjct: 1910 TEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPR-RP 1968

Query: 189  YIHPTESSSPPPEKGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTP 237
            +    E+ S PP   ++S      SP   +P+  P+A       L   P
Sbjct: 1969 WSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDP 2017


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 57/232 (24%), Positives = 87/232 (37%), Gaps = 43/232 (18%)

Query: 98  PPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKAR--------- 148
           PPPV    RP+  + P  RG        ++ SP      P+ P +P  +           
Sbjct: 184 PPPVPSTPRPIQSS-PHNRGSPPVPGGPRQPSPG-----PTPPPFPGNRGTALGGGSIRQ 237

Query: 149 --LTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIH-------PTESSSPP 199
             L+S+ P      +P +PP P   L+D+     P   N  + IH       P +++ PP
Sbjct: 238 SPLSSSSPFSN---RPPLPPTPSRALDDKPPPPPPPVGNRPS-IHREAVPPPPPQNNKPP 293

Query: 200 -PEKGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERH 258
            P   R S + +   PPP    P P      ++    TP   Q+N S      P+P+   
Sbjct: 294 VPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGR 353

Query: 259 RGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNST 310
            G          P+ PP      ++P P  R   G +  +  P P   + ST
Sbjct: 354 SG----------PLPPPPS----ERPPPPVRDPPGRSGPLPPPPPVSRNGST 391



 Score = 30.4 bits (67), Expect = 3.3
 Identities = 38/145 (26%), Positives = 46/145 (31%), Gaps = 36/145 (24%)

Query: 95  SYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLP 154
           S  PPP    +RP  P L                 PP S      P  P     L+S+ P
Sbjct: 304 SQAPPPPPPPSRPGPPPL-----------------PPSSSGNDETPRLPQRNLSLSSSTP 346

Query: 155 ALTAL-QKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESS--SPPPEKGRNSGAWET 211
            L +  +   +PP P            PV D       P  S    PPP   RN      
Sbjct: 347 PLPSPGRSGPLPPPPSERPPP------PVRD------PPGRSGPLPPPPPVSRNGSTSRA 394

Query: 212 KSPPPAAPS----PLPRAGKKPTTP 232
               P  PS      PR+G +P  P
Sbjct: 395 LPATPQLPSRSGVDSPRSGPRPPLP 419



 Score = 28.9 bits (63), Expect = 9.5
 Identities = 41/178 (23%), Positives = 55/178 (30%), Gaps = 39/178 (21%)

Query: 161 KPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGRNSGAWETKSPPPAAPS 220
           KP  PP   G       + VP   +      P  +  PPP     S       P P+ P 
Sbjct: 139 KPFSPPSGPGR------FPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPR 192

Query: 221 PLPRAGKKPTTPLKTTPV-ASQQNASSVCEEKPIPAERHR---GSSHRQEAVQS------ 270
           P+  +     +P    PV    +  S      P P  R     G S RQ  + S      
Sbjct: 193 PIQSSPHNRGSP----PVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSN 248

Query: 271 -PVFPPA------------------QKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNS 309
            P  PP                   +  IH++ +P P       P    P PS SS +
Sbjct: 249 RPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQA 306


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 57/232 (24%), Positives = 87/232 (37%), Gaps = 43/232 (18%)

Query: 98  PPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKAR--------- 148
           PPPV    RP+  + P  RG        ++ SP      P+ P +P  +           
Sbjct: 184 PPPVPSTPRPIQSS-PHNRGSPPVPGGPRQPSPG-----PTPPPFPGNRGTALGGGSIRQ 237

Query: 149 --LTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIH-------PTESSSPP 199
             L+S+ P      +P +PP P   L+D+     P   N  + IH       P +++ PP
Sbjct: 238 SPLSSSSPFSN---RPPLPPTPSRALDDKPPPPPPPVGNRPS-IHREAVPPPPPQNNKPP 293

Query: 200 -PEKGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERH 258
            P   R S + +   PPP    P P      ++    TP   Q+N S      P+P+   
Sbjct: 294 VPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGR 353

Query: 259 RGSSHRQEAVQSPVFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNST 310
            G          P+ PP      ++P P  R   G +  +  P P   + ST
Sbjct: 354 SG----------PLPPPPS----ERPPPPVRDPPGRSGPLPPPPPVSRNGST 391



 Score = 30.4 bits (67), Expect = 3.3
 Identities = 38/145 (26%), Positives = 46/145 (31%), Gaps = 36/145 (24%)

Query: 95  SYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKARLTSTLP 154
           S  PPP    +RP  P L                 PP S      P  P     L+S+ P
Sbjct: 304 SQAPPPPPPPSRPGPPPL-----------------PPSSSGNDETPRLPQRNLSLSSSTP 346

Query: 155 ALTAL-QKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESS--SPPPEKGRNSGAWET 211
            L +  +   +PP P            PV D       P  S    PPP   RN      
Sbjct: 347 PLPSPGRSGPLPPPPSERPPP------PVRD------PPGRSGPLPPPPPVSRNGSTSRA 394

Query: 212 KSPPPAAPS----PLPRAGKKPTTP 232
               P  PS      PR+G +P  P
Sbjct: 395 LPATPQLPSRSGVDSPRSGPRPPLP 419



 Score = 28.9 bits (63), Expect = 9.5
 Identities = 41/178 (23%), Positives = 55/178 (30%), Gaps = 39/178 (21%)

Query: 161 KPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGRNSGAWETKSPPPAAPS 220
           KP  PP   G       + VP   +      P  +  PPP     S       P P+ P 
Sbjct: 139 KPFSPPSGPGR------FPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPR 192

Query: 221 PLPRAGKKPTTPLKTTPV-ASQQNASSVCEEKPIPAERHR---GSSHRQEAVQS------ 270
           P+  +     +P    PV    +  S      P P  R     G S RQ  + S      
Sbjct: 193 PIQSSPHNRGSP----PVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSN 248

Query: 271 -PVFPPA------------------QKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNS 309
            P  PP                   +  IH++ +P P       P    P PS SS +
Sbjct: 249 RPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQA 306


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
           sapiens]
          Length = 2715

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 55/213 (25%), Positives = 79/213 (37%), Gaps = 36/213 (16%)

Query: 87  PAEENADDSYEPPPVEQET----RPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSW 142
           PA+E  ++S  PPPV   T    R   P  P  R E    R+    + P + T  +    
Sbjct: 448 PAQEEQEES--PPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGG 505

Query: 143 PSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPT-----ESSS 197
           P E +              P V PK    L++   +++PV     + +  T     +   
Sbjct: 506 PPEDS--------------PTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDP 551

Query: 198 PPPEKGRNSGAWE---TKSPP-PAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPI 253
           P P K   S       T SPP P  P+P+P   + PT P  +TPV   +   S+  E   
Sbjct: 552 PKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPP--STPVPLPEKRRSILREPTF 609

Query: 254 PAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIP 286
                R +S  +E    P  PP        P P
Sbjct: 610 -----RWTSLTRELPPPPPAPPPPPAPSPPPAP 637



 Score = 33.5 bits (75), Expect = 0.39
 Identities = 32/126 (25%), Positives = 42/126 (33%), Gaps = 10/126 (7%)

Query: 176 ADYVVPVEDNDENYIHPTESSSPPPEKGRNSGAWETKSPPPAAPSPLPRAGKKPTTPLKT 235
           A+ ++P  + +E  + P   + P P          T SPPP    P P     P  P   
Sbjct: 387 AEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPST-SPPPPLCPPPPPPVSPPPLPSPP 445

Query: 236 TPVASQQNASSVCEEKPIPAERHRG-----SSHRQEAVQSPVFPPAQKQIHQKPIPLPRF 290
            P A ++   S     P    R RG      S R E   +   P         P P P  
Sbjct: 446 PPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGT----SPPTPTPST 501

Query: 291 TEGGNP 296
             GG P
Sbjct: 502 ATGGPP 507



 Score = 29.6 bits (65), Expect = 5.6
 Identities = 33/135 (24%), Positives = 50/135 (37%), Gaps = 27/135 (20%)

Query: 82  EMYVMPAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTL----- 136
           E  + P    A ++ EP P   +  P  P  P A G   ++ S  R +P  +  +     
Sbjct: 663 ESVLTPPPLGAPEAPEPEPPPADDSPAEPE-PRAVGR-TNHLSLPRFAPVVTTPVKAEVS 720

Query: 137 ----PSKPSWPSEKARLTSTLPALTALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHP 192
               P+  + P  +A+L   L AL     PQ  P P+  L+                  P
Sbjct: 721 PHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPP----------------P 764

Query: 193 TESSSPPPEKGRNSG 207
           +    PP EK R +G
Sbjct: 765 SPQQMPPLEKARIAG 779


>gi|130977759 tec protein tyrosine kinase [Homo sapiens]
          Length = 631

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 38/120 (31%), Positives = 55/120 (45%), Gaps = 29/120 (24%)

Query: 323 WYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQP--YTLVVF--------FNKRVYN 372
           WY    +R  AE+ L   +K+G F++R     DS QP  YT+ ++           R Y+
Sbjct: 247 WYCRNMNRSKAEQLLRSEDKEGGFMVR-----DSSQPGLYTVSLYTKFGGEGSSGFRHYH 301

Query: 373 IPVRFIEATKQYALGRKKNGEEYFGSVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAVKV 432
           I      + K+Y L  K      FGS+ EII  H+H+   L+         TRL+Y V V
Sbjct: 302 IK-ETTTSPKKYYLAEK----HAFGSIPEIIEYHKHNAAGLV---------TRLRYPVSV 347


>gi|148596974 TXK tyrosine kinase [Homo sapiens]
          Length = 527

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 37/115 (32%), Positives = 53/115 (46%), Gaps = 25/115 (21%)

Query: 323 WYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRFIEAT- 381
           WY     R  AE  L + +K+G+F++R S    S   YT+ VF   R      R  EA  
Sbjct: 150 WYHRNITRNQAEHLLRQESKEGAFIVRDSRHLGS---YTISVFMGAR------RSTEAAI 200

Query: 382 KQYALGRKKNGEEY------FGSVAEIIRNHQHSPLVLIDSQNNTKDSTRLKYAV 430
           K Y + +  +G+ Y      F S+ E+I  HQH+   L+         TRL+Y V
Sbjct: 201 KHYQIKKNDSGQWYVAERHAFQSIPELIWYHQHNAAGLM---------TRLRYPV 246


>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
          Length = 863

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 35/118 (29%), Positives = 49/118 (41%), Gaps = 18/118 (15%)

Query: 200 PEKGRNSGAW-ETKSPPPAAPSPLPRAGKKPTTPLKTTP----------VASQQNASSVC 248
           P K R  G   E  SPP   P+P PR   + TTP   TP          +  Q  +SS+ 
Sbjct: 281 PTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSSLV 340

Query: 249 EEK--PIPAERHRGSSHRQEAVQSPVFPP-----AQKQIHQKPIPLPRFTEGGNPTVD 299
             +   +P  + RG+    E   +P   P      Q +  +KP PLP  +  G P+ D
Sbjct: 341 NGRLHELPVPKPRGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQD 398



 Score = 33.1 bits (74), Expect = 0.50
 Identities = 67/302 (22%), Positives = 105/302 (34%), Gaps = 56/302 (18%)

Query: 87  PAEENADDSYEPPPVEQETRPVHPALPFARGEYIDNRSSQRHSP---PFSKTLPSKPSWP 143
           PA   AD     P    E RP  P  P   G+  +  S     P   P   +  + P+ P
Sbjct: 262 PAGAEADG----PKASPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPP 317

Query: 144 SEKARLT---------STLPALTALQKPQVP-PKPKGLLEDEADYVVPVED--------- 184
           + + R +         +   +L   +  ++P PKP+G  +       P +D         
Sbjct: 318 TPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRGTPKPSEGTPAPRKDPPWITLVQA 377

Query: 185 ---NDENYIHPTESSSPPPEKGR---NSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPV 238
                   + P+ S  PP +  R   N G  E      A PSP      KP  P +    
Sbjct: 378 EPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEV-----AQPSPTASLESKPYNPFEEEEE 432

Query: 239 ASQQNASSVCEEKPIPAERHRGSSHRQEAVQSPVFPPAQKQIHQKPIP-----------L 287
             ++ A +       PA  H  S+ +       + P +  +  ++P P            
Sbjct: 433 DKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAPRAPSASPLALHA 492

Query: 288 PRFTEGGNPTVDGPLPSFSSNSTISE---QEAGV-LCKPWYAGACDRKSAEEALHRSNKD 343
            R +    P+   P P+ S  S  SE   Q AG  L +P    A  + S+E A+H     
Sbjct: 493 SRLSHSEPPSAT-PSPALSVESLSSESASQTAGAELLEP---PAVPKSSSEPAVHAPGTP 548

Query: 344 GS 345
           G+
Sbjct: 549 GN 550


>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
            [Homo sapiens]
          Length = 1285

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 79/341 (23%), Positives = 116/341 (34%), Gaps = 74/341 (21%)

Query: 99   PPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKAR---------- 148
            PPV Q      P LP   G   +  +    SP F  + PS   WP E++           
Sbjct: 823  PPVSQAGTGKAPELPSGSGP--EPLAPSPVSPTFPPSSPS--DWPQERSPGGHSDGASPR 878

Query: 149  --LTSTLPAL--TALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGR 204
              + +TLP L     Q P+ PP                +  D + + P  S  P      
Sbjct: 879  SPVPTTLPGLRHAPWQGPRGPP----------------DSPDGSPLTPVPSQMP------ 916

Query: 205  NSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHR 264
                W   SP P   SP P             P+A+  + + +  + P+P +RH     +
Sbjct: 917  ----WLVASPEPPQSSPTP-----------AFPLAASYDTNGL-SQPPLPEKRHLPGPGQ 960

Query: 265  QEAVQSP--VFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKP 322
            Q     P     PA+   H      P  ++    T + P     SN    +  +    K 
Sbjct: 961  QPGPWGPEQASSPARGISHHVTFA-PLLSDNVPQTPEPPTQESQSNVKFVQDTS----KF 1015

Query: 323  WYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVV---------FFNKRVYNI 373
            WY     R  A  AL +    G+FLIR S          L V         +    V  +
Sbjct: 1016 WYKPHLSRDQAI-ALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQL 1074

Query: 374  PVRFIEATKQYALGRKK-NGEEYFGSVAEIIRNHQHSPLVL 413
               F+  T    +  K    E YFGS++ ++  H  SP+ L
Sbjct: 1075 VRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISL 1115


>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
            [Homo sapiens]
          Length = 1409

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 79/341 (23%), Positives = 116/341 (34%), Gaps = 74/341 (21%)

Query: 99   PPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKAR---------- 148
            PPV Q      P LP   G   +  +    SP F  + PS   WP E++           
Sbjct: 947  PPVSQAGTGKAPELPSGSGP--EPLAPSPVSPTFPPSSPS--DWPQERSPGGHSDGASPR 1002

Query: 149  --LTSTLPAL--TALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGR 204
              + +TLP L     Q P+ PP                +  D + + P  S  P      
Sbjct: 1003 SPVPTTLPGLRHAPWQGPRGPP----------------DSPDGSPLTPVPSQMP------ 1040

Query: 205  NSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHR 264
                W   SP P   SP P             P+A+  + + +  + P+P +RH     +
Sbjct: 1041 ----WLVASPEPPQSSPTP-----------AFPLAASYDTNGL-SQPPLPEKRHLPGPGQ 1084

Query: 265  QEAVQSP--VFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKP 322
            Q     P     PA+   H      P  ++    T + P     SN    +  +    K 
Sbjct: 1085 QPGPWGPEQASSPARGISHHVTFA-PLLSDNVPQTPEPPTQESQSNVKFVQDTS----KF 1139

Query: 323  WYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVV---------FFNKRVYNI 373
            WY     R  A  AL +    G+FLIR S          L V         +    V  +
Sbjct: 1140 WYKPHLSRDQAI-ALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQL 1198

Query: 374  PVRFIEATKQYALGRKK-NGEEYFGSVAEIIRNHQHSPLVL 413
               F+  T    +  K    E YFGS++ ++  H  SP+ L
Sbjct: 1199 VRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISL 1239


>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
            [Homo sapiens]
          Length = 1419

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 79/341 (23%), Positives = 116/341 (34%), Gaps = 74/341 (21%)

Query: 99   PPVEQETRPVHPALPFARGEYIDNRSSQRHSPPFSKTLPSKPSWPSEKAR---------- 148
            PPV Q      P LP   G   +  +    SP F  + PS   WP E++           
Sbjct: 957  PPVSQAGTGKAPELPSGSGP--EPLAPSPVSPTFPPSSPS--DWPQERSPGGHSDGASPR 1012

Query: 149  --LTSTLPAL--TALQKPQVPPKPKGLLEDEADYVVPVEDNDENYIHPTESSSPPPEKGR 204
              + +TLP L     Q P+ PP                +  D + + P  S  P      
Sbjct: 1013 SPVPTTLPGLRHAPWQGPRGPP----------------DSPDGSPLTPVPSQMP------ 1050

Query: 205  NSGAWETKSPPPAAPSPLPRAGKKPTTPLKTTPVASQQNASSVCEEKPIPAERHRGSSHR 264
                W   SP P   SP P             P+A+  + + +  + P+P +RH     +
Sbjct: 1051 ----WLVASPEPPQSSPTP-----------AFPLAASYDTNGL-SQPPLPEKRHLPGPGQ 1094

Query: 265  QEAVQSP--VFPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKP 322
            Q     P     PA+   H      P  ++    T + P     SN    +  +    K 
Sbjct: 1095 QPGPWGPEQASSPARGISHHVTFA-PLLSDNVPQTPEPPTQESQSNVKFVQDTS----KF 1149

Query: 323  WYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVV---------FFNKRVYNI 373
            WY     R  A  AL +    G+FLIR S          L V         +    V  +
Sbjct: 1150 WYKPHLSRDQAI-ALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQL 1208

Query: 374  PVRFIEATKQYALGRKK-NGEEYFGSVAEIIRNHQHSPLVL 413
               F+  T    +  K    E YFGS++ ++  H  SP+ L
Sbjct: 1209 VRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISL 1249


>gi|4506431 RAS p21 protein activator 1 isoform 1 [Homo sapiens]
          Length = 1047

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 40/147 (27%), Positives = 66/147 (44%), Gaps = 23/147 (15%)

Query: 273 FPPAQKQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGV-LCKP----WYAGA 327
           FPP     +  P+     T     ++DGP           E+E  + L  P    WY G 
Sbjct: 134 FPPLPPPPYLPPLGAGLGTVDEGDSLDGP--------EYEEEEVAIPLTAPPTNQWYHGK 185

Query: 328 CDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNI-PVRFIEATKQYAL 386
            DR  AEE L ++ K GS+LIR+S     ++P + V+ F  ++  +   R I     Y +
Sbjct: 186 LDRTIAEERLRQAGKSGSYLIRES----DRRPGSFVLSFLSQMNVVNHFRIIAMCGDYYI 241

Query: 387 GRKKNGEEYFGSVAEIIRNHQHSPLVL 413
           G ++     F S++++I  + H   +L
Sbjct: 242 GGRR-----FSSLSDLIGYYSHVSCLL 263


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.128    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,198,837
Number of Sequences: 37866
Number of extensions: 1306489
Number of successful extensions: 9632
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 141
Number of HSP's successfully gapped in prelim test: 713
Number of HSP's that attempted gapping in prelim test: 7172
Number of HSP's gapped (non-prelim): 2254
length of query: 433
length of database: 18,247,518
effective HSP length: 105
effective length of query: 328
effective length of database: 14,271,588
effective search space: 4681080864
effective search space used: 4681080864
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press