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Search of human proteins with 164565366
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|164565366 TBC1 domain family, member 14 isoform a [Homo
sapiens]
(693 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens] 1393 0.0
gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens] 1393 0.0
gi|164565381 TBC1 domain family, member 14 isoform b [Homo sapiens] 841 0.0
gi|148806902 TBC1 domain family, member 12 [Homo sapiens] 663 0.0
gi|68299759 ecotropic viral integration site 5 [Homo sapiens] 107 4e-23
gi|164519084 RAB GTPase activating protein 1 [Homo sapiens] 107 5e-23
gi|78217386 RAB GTPase activating protein 1-like isoform A [Homo... 106 6e-23
gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens] 104 2e-22
gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens] 104 2e-22
gi|229577000 ecotropic viral integration site 5-like isoform 1 [... 103 7e-22
gi|21687020 ecotropic viral integration site 5-like isoform 2 [H... 103 7e-22
gi|114688046 TBC1 domain family, member 4 [Homo sapiens] 99 2e-20
gi|13994322 TBC1 domain family, member 10A [Homo sapiens] 95 2e-19
gi|167614488 TBC1 domain family, member 10B [Homo sapiens] 92 2e-18
gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member... 89 1e-17
gi|38348348 TBC1 domain family, member 10C [Homo sapiens] 87 7e-17
gi|29648315 small G protein signaling modulator 3 [Homo sapiens] 86 2e-16
gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens] 83 1e-15
gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens] 83 1e-15
gi|226693407 TBC1 domain family, member 3H [Homo sapiens] 77 4e-14
gi|157502205 TBC1 domain family, member 3G [Homo sapiens] 77 4e-14
gi|183583565 TBC1 domain family, member 3 [Homo sapiens] 77 5e-14
gi|183583567 TBC1 domain family, member 3E [Homo sapiens] 77 5e-14
gi|183583563 TBC1 domain family, member 3D [Homo sapiens] 77 5e-14
gi|14149985 TBC1 domain family, member 3F [Homo sapiens] 77 7e-14
gi|90577185 TBC1 domain family member 3C [Homo sapiens] 74 3e-13
gi|38570101 TBC1 domain family, member 8B (with GRAM domain) iso... 73 8e-13
gi|149999613 TBC1 domain family, member 3B [Homo sapiens] 73 1e-12
gi|109638751 ubiquitin specific protease 6 [Homo sapiens] 72 2e-12
gi|222352143 TBC1 domain family, member 2 [Homo sapiens] 67 6e-11
>gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens]
Length = 693
Score = 1393 bits (3606), Expect = 0.0
Identities = 693/693 (100%), Positives = 693/693 (100%)
Query: 1 MTDGKLSTSTNGVAFMGILDGRPGNPLQNLQHVNLKAPRLLSAPEYGPKLKLRALEDRHS 60
MTDGKLSTSTNGVAFMGILDGRPGNPLQNLQHVNLKAPRLLSAPEYGPKLKLRALEDRHS
Sbjct: 1 MTDGKLSTSTNGVAFMGILDGRPGNPLQNLQHVNLKAPRLLSAPEYGPKLKLRALEDRHS 60
Query: 61 LQSVDSGIPTLEIGNPEPVPCSAVHVRRKQSDSDLIPERAFQSACALPSCAPPAPSSTER 120
LQSVDSGIPTLEIGNPEPVPCSAVHVRRKQSDSDLIPERAFQSACALPSCAPPAPSSTER
Sbjct: 61 LQSVDSGIPTLEIGNPEPVPCSAVHVRRKQSDSDLIPERAFQSACALPSCAPPAPSSTER 120
Query: 121 EQSVRKSSTFPRTGYDSVKLYSPTSKALTRSDDVSVCSVSSLGTELSTTLSVSNEDILDL 180
EQSVRKSSTFPRTGYDSVKLYSPTSKALTRSDDVSVCSVSSLGTELSTTLSVSNEDILDL
Sbjct: 121 EQSVRKSSTFPRTGYDSVKLYSPTSKALTRSDDVSVCSVSSLGTELSTTLSVSNEDILDL 180
Query: 181 VVTSSSSAIVTLENDDDPQFTNVTLSSIKETRGLHQQDCVHEAEEGSKLKILGPFSNFFA 240
VVTSSSSAIVTLENDDDPQFTNVTLSSIKETRGLHQQDCVHEAEEGSKLKILGPFSNFFA
Sbjct: 181 VVTSSSSAIVTLENDDDPQFTNVTLSSIKETRGLHQQDCVHEAEEGSKLKILGPFSNFFA 240
Query: 241 RNLLARKQSARLDKHNDLGWKLFGKAPLRENAQKDSKRIQKEYEDKAGRPSKPPSPKQNV 300
RNLLARKQSARLDKHNDLGWKLFGKAPLRENAQKDSKRIQKEYEDKAGRPSKPPSPKQNV
Sbjct: 241 RNLLARKQSARLDKHNDLGWKLFGKAPLRENAQKDSKRIQKEYEDKAGRPSKPPSPKQNV 300
Query: 301 RKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELKEAQRRKKQL 360
RKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELKEAQRRKKQL
Sbjct: 301 RKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELKEAQRRKKQL 360
Query: 361 EERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELN 420
EERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELN
Sbjct: 361 EERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELN 420
Query: 421 ITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIF 480
ITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIF
Sbjct: 421 ITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIF 480
Query: 481 QQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQM 540
QQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQM
Sbjct: 481 QQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQM 540
Query: 541 AFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLA 600
AFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLA
Sbjct: 541 AFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLA 600
Query: 601 CRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQFLTRLPEDLPAEELFASIAT 660
CRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQFLTRLPEDLPAEELFASIAT
Sbjct: 601 CRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQFLTRLPEDLPAEELFASIAT 660
Query: 661 IQMQSRNKKWAQVLTALQKDSREMEKGSPSLRH 693
IQMQSRNKKWAQVLTALQKDSREMEKGSPSLRH
Sbjct: 661 IQMQSRNKKWAQVLTALQKDSREMEKGSPSLRH 693
>gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens]
Length = 693
Score = 1393 bits (3606), Expect = 0.0
Identities = 693/693 (100%), Positives = 693/693 (100%)
Query: 1 MTDGKLSTSTNGVAFMGILDGRPGNPLQNLQHVNLKAPRLLSAPEYGPKLKLRALEDRHS 60
MTDGKLSTSTNGVAFMGILDGRPGNPLQNLQHVNLKAPRLLSAPEYGPKLKLRALEDRHS
Sbjct: 1 MTDGKLSTSTNGVAFMGILDGRPGNPLQNLQHVNLKAPRLLSAPEYGPKLKLRALEDRHS 60
Query: 61 LQSVDSGIPTLEIGNPEPVPCSAVHVRRKQSDSDLIPERAFQSACALPSCAPPAPSSTER 120
LQSVDSGIPTLEIGNPEPVPCSAVHVRRKQSDSDLIPERAFQSACALPSCAPPAPSSTER
Sbjct: 61 LQSVDSGIPTLEIGNPEPVPCSAVHVRRKQSDSDLIPERAFQSACALPSCAPPAPSSTER 120
Query: 121 EQSVRKSSTFPRTGYDSVKLYSPTSKALTRSDDVSVCSVSSLGTELSTTLSVSNEDILDL 180
EQSVRKSSTFPRTGYDSVKLYSPTSKALTRSDDVSVCSVSSLGTELSTTLSVSNEDILDL
Sbjct: 121 EQSVRKSSTFPRTGYDSVKLYSPTSKALTRSDDVSVCSVSSLGTELSTTLSVSNEDILDL 180
Query: 181 VVTSSSSAIVTLENDDDPQFTNVTLSSIKETRGLHQQDCVHEAEEGSKLKILGPFSNFFA 240
VVTSSSSAIVTLENDDDPQFTNVTLSSIKETRGLHQQDCVHEAEEGSKLKILGPFSNFFA
Sbjct: 181 VVTSSSSAIVTLENDDDPQFTNVTLSSIKETRGLHQQDCVHEAEEGSKLKILGPFSNFFA 240
Query: 241 RNLLARKQSARLDKHNDLGWKLFGKAPLRENAQKDSKRIQKEYEDKAGRPSKPPSPKQNV 300
RNLLARKQSARLDKHNDLGWKLFGKAPLRENAQKDSKRIQKEYEDKAGRPSKPPSPKQNV
Sbjct: 241 RNLLARKQSARLDKHNDLGWKLFGKAPLRENAQKDSKRIQKEYEDKAGRPSKPPSPKQNV 300
Query: 301 RKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELKEAQRRKKQL 360
RKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELKEAQRRKKQL
Sbjct: 301 RKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELKEAQRRKKQL 360
Query: 361 EERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELN 420
EERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELN
Sbjct: 361 EERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELN 420
Query: 421 ITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIF 480
ITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIF
Sbjct: 421 ITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIF 480
Query: 481 QQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQM 540
QQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQM
Sbjct: 481 QQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQM 540
Query: 541 AFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLA 600
AFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLA
Sbjct: 541 AFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLA 600
Query: 601 CRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQFLTRLPEDLPAEELFASIAT 660
CRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQFLTRLPEDLPAEELFASIAT
Sbjct: 601 CRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQFLTRLPEDLPAEELFASIAT 660
Query: 661 IQMQSRNKKWAQVLTALQKDSREMEKGSPSLRH 693
IQMQSRNKKWAQVLTALQKDSREMEKGSPSLRH
Sbjct: 661 IQMQSRNKKWAQVLTALQKDSREMEKGSPSLRH 693
>gi|164565381 TBC1 domain family, member 14 isoform b [Homo sapiens]
Length = 413
Score = 841 bits (2173), Expect = 0.0
Identities = 412/412 (100%), Positives = 412/412 (100%)
Query: 282 EYEDKAGRPSKPPSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEM 341
EYEDKAGRPSKPPSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEM
Sbjct: 2 EYEDKAGRPSKPPSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEM 61
Query: 342 VVQAKKRELKEAQRRKKQLEERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQG 401
VVQAKKRELKEAQRRKKQLEERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQG
Sbjct: 62 VVQAKKRELKEAQRRKKQLEERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQG 121
Query: 402 IPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREA 461
IPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREA
Sbjct: 122 IPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREA 181
Query: 462 SLELIKLDISRTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNL 521
SLELIKLDISRTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNL
Sbjct: 182 SLELIKLDISRTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNL 241
Query: 522 DTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDI 581
DTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDI
Sbjct: 242 DTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDI 301
Query: 582 YLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQF 641
YLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQF
Sbjct: 302 YLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQF 361
Query: 642 LTRLPEDLPAEELFASIATIQMQSRNKKWAQVLTALQKDSREMEKGSPSLRH 693
LTRLPEDLPAEELFASIATIQMQSRNKKWAQVLTALQKDSREMEKGSPSLRH
Sbjct: 362 LTRLPEDLPAEELFASIATIQMQSRNKKWAQVLTALQKDSREMEKGSPSLRH 413
>gi|148806902 TBC1 domain family, member 12 [Homo sapiens]
Length = 775
Score = 663 bits (1710), Expect = 0.0
Identities = 325/462 (70%), Positives = 387/462 (83%), Gaps = 5/462 (1%)
Query: 233 GPFSNFFARNLLARK-QSARLDKHNDLGWKLFGKAPLRENAQKDSKRIQKEYEDKAGRPS 291
G F++FF RNL ++ + + H+ GWKLFGK P REN QK SK IQ+EYE + GR
Sbjct: 316 GGFADFFTRNLFPKRTKELKSVVHSAPGWKLFGKVPPRENLQKTSKIIQQEYEARTGRTC 375
Query: 292 KPPSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELK 351
KPP P+ + RKN +FEPLSTTALILEDRP+NLPAK EEA +HRQ+Y+EMV +AKKRE+K
Sbjct: 376 KPP-PQSSRRKNFEFEPLSTTALILEDRPSNLPAKSVEEALRHRQEYDEMVAEAKKREIK 434
Query: 352 EAQRRKKQLEERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQGIPPSVRGKVW 411
EA +RK+ ++ER + EE+I +A++ W NEILPNWE M +R+VR+LWWQG+PPSVRGKVW
Sbjct: 435 EAHKRKRIMKERFKQEENIASAMVIWINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVW 494
Query: 412 SLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDIS 471
SLA+GNELNIT EL++I L+RAKERW+S S SE N+ G S ADREASLELIKLDIS
Sbjct: 495 SLAVGNELNITPELYEIFLSRAKERWKSFSETSSE--NDTEGVSVADREASLELIKLDIS 552
Query: 472 RTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFS 531
RTFP+L IFQ+GGPYHD+LHSILGAYTCYRPDVGYVQGMSFIAAVLILNL+ ADAFIAF+
Sbjct: 553 RTFPSLYIFQKGGPYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFA 612
Query: 532 NLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLY 591
NLLNKPCQ+AFFRVDH +ML YFA FEVFFEENL KLF HFK +LTPDIYLIDWIFTLY
Sbjct: 613 NLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLY 672
Query: 592 SKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQFLTRLPEDLPA 651
SKSLPLDLACR+WDVFCRDGEEFLFRT LGIL+L+EDIL +MDFIH+AQFLT+LPED+ +
Sbjct: 673 SKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYEDILLQMDFIHIAQFLTKLPEDITS 732
Query: 652 EELFASIATIQMQSRNKKWAQVLTALQKDSREMEK-GSPSLR 692
E+LF+ IA IQMQ+ KKW QV ++ KD +E +K SP+L+
Sbjct: 733 EKLFSCIAAIQMQNSTKKWTQVFASVMKDIKEGDKNSSPALK 774
>gi|68299759 ecotropic viral integration site 5 [Homo sapiens]
Length = 810
Score = 107 bits (267), Expect = 4e-23
Identities = 97/412 (23%), Positives = 178/412 (43%), Gaps = 49/412 (11%)
Query: 291 SKPPSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKREL 350
S+ SP ++ LST AL P+ L E K +Q + +K
Sbjct: 47 SQVASPSTSLHTTSSSTTLSTPALS-PSSPSQLSPDDLELLAKLEEQNRLLETDSKSLRS 105
Query: 351 KEAQRRKK--QLEERCRVEESIGN----AVLTWNNEILPNWETMWCSRK--VRDLWWQGI 402
RR L ++ + + + W I+ WE + ++ V++L +GI
Sbjct: 106 VNGSRRNSGSSLVSSSSASSNLSHLEEDSWILWGR-IVNEWEDVRKKKEKQVKELVHKGI 164
Query: 403 PPSVRGKVWSLAIGNELNITHELFDICLARA---KERWRSLSTGGSEVENEDAGFSAADR 459
P R VW L +C A++ K+++ L S E
Sbjct: 165 PHHFRAIVWQL--------------LCSAQSMPIKDQYSELLKMTSPCE----------- 199
Query: 460 EASLELIKLDISRTFPNLCIFQQGGPY-HDMLHSILGAYTCYRPDVGYVQGMSFIAAVLI 518
+LI+ DI+RT+P F++ ++L +++ AY+ +VGY QG +FI +L+
Sbjct: 200 ----KLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLL 255
Query: 519 LNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLT 578
+ + +AF F L+ F+ + FE +E+LP+LF HF+ +
Sbjct: 256 MQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQEHLPELFVHFQSQSFH 315
Query: 579 PDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHM 638
+Y W T++ + PL +A RI+D+F +G E +FR L +L++ + L ++D M
Sbjct: 316 TSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQMNQAELMQLDMEGM 375
Query: 639 AQFLTRLP----EDLPAEELFASIATIQMQSRNKKWAQVLTALQKDSREMEK 686
Q ++ + +P + + A+ + KK + T ++ ++EME+
Sbjct: 376 LQHFQKVIPHQFDGVPDKLIQAAYQVKYNSKKMKKLEKEYTTIK--TKEMEE 425
>gi|164519084 RAB GTPase activating protein 1 [Homo sapiens]
Length = 1069
Score = 107 bits (266), Expect = 5e-23
Identities = 93/361 (25%), Positives = 147/361 (40%), Gaps = 29/361 (8%)
Query: 297 KQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELKEAQRR 356
KQ RKN L E + + + + V+ + + +E
Sbjct: 460 KQRERKNNTDTLYEVVCLESESERERRKTTASPSVRLPQSGSQSSVIPSPPEDDEEEDND 519
Query: 357 KKQLEERCRVEESIGNAVLTWNNEILPNWETMWCSR--KVRDLWWQGIPPSVRGKVWSLA 414
+ L V + +L E+L W R ++ L G+P ++RG+VW L
Sbjct: 520 EPLLSGSGDVSKECAEKILETWGELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLL 579
Query: 415 IGNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTF 474
G N E++R L T S ++ I DI+RTF
Sbjct: 580 AGCHNN----------DHLVEKYRILITKESPQDSA---------------ITRDINRTF 614
Query: 475 PNLCIFQQ-GGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNL 533
P F+ GG D L+ I AY+ Y ++GY QG SF+AAVL+L++ AF +
Sbjct: 615 PAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLLHMPEEQAFSVLVKI 674
Query: 534 LNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSK 593
+ F+ + + F E +E +P L+ HF +L +Y W TL++
Sbjct: 675 MFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEAHMYASQWFLTLFTA 734
Query: 594 SLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQFL-TRLPEDLPAE 652
PL + I D+ +G +F ALG+LK +D L DF +F +LP+ +E
Sbjct: 735 KFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFFRVQLPKRYRSE 794
Query: 653 E 653
E
Sbjct: 795 E 795
>gi|78217386 RAB GTPase activating protein 1-like isoform A [Homo
sapiens]
Length = 815
Score = 106 bits (265), Expect = 6e-23
Identities = 82/278 (29%), Positives = 124/278 (44%), Gaps = 29/278 (10%)
Query: 380 EILPNWETMWCSRK--VRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERW 437
E+L W + +R + L G+P ++R +VW L G N +R+
Sbjct: 515 ELLGKWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDN----------QAMLDRY 564
Query: 438 RSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQ-GGPYHDMLHSILGA 496
R L T S E+ +I DI RTFP F+ GG + L+ I A
Sbjct: 565 RILITKDSAQES---------------VITRDIHRTFPAHDYFKDTGGDGQESLYKICKA 609
Query: 497 YTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAA 556
Y+ Y D+GY QG SF+AAVL+L++ AF ++ +R + + F
Sbjct: 610 YSVYDEDIGYCQGQSFLAAVLLLHMPEEQAFCVLVKIMYDYGLRDLYRNNFEDLHCKFYQ 669
Query: 557 FEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLF 616
E +E LP L +HF NL +Y W TL++ PL + I D+ +G +F
Sbjct: 670 LERLMQEQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIF 729
Query: 617 RTALGILKLFEDILTKMDFIHMAQFL-TRLPEDLPAEE 653
AL +LK ++ L + DF +F +LP+ AEE
Sbjct: 730 HVALALLKTSKEDLLQADFEGALKFFRVQLPKRYRAEE 767
>gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens]
Length = 828
Score = 104 bits (260), Expect = 2e-22
Identities = 84/298 (28%), Positives = 134/298 (44%), Gaps = 26/298 (8%)
Query: 380 EILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRS 439
++L WE + K ++GIP +RG+VW+L + + + KE R
Sbjct: 79 KMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLE-------------IPKMKEETRD 125
Query: 440 LSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQG-GPYHDMLHSILGAYT 498
L S++++ G S R+ I LD++RTF + +F+ G L +L AY+
Sbjct: 126 LY---SKLKHRARGCSPDIRQ-----IDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYS 177
Query: 499 CYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKP--CQMAFFRVDHGLMLTYFAA 556
Y +VGY QGMS I A+L++ ++ DAF A L + P FF +L +
Sbjct: 178 IYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEH 237
Query: 557 FEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLF 616
E + L KL H + Y + W F + P L RIWD++ +GE L
Sbjct: 238 HEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLT 297
Query: 617 RTALGILKLFEDILTKMDFIHMAQFLTR-LPEDLPAEELFASIATIQMQSRNKKWAQV 673
+ ILKL + L K+ + +F L +D E+ F I +Q+ K A++
Sbjct: 298 AMSYTILKLHKKHLMKLSMEELVEFFQETLAKDFFFEDDFV-IEQLQISMTELKRAKL 354
>gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens]
Length = 845
Score = 104 bits (260), Expect = 2e-22
Identities = 84/298 (28%), Positives = 134/298 (44%), Gaps = 26/298 (8%)
Query: 380 EILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRS 439
++L WE + K ++GIP +RG+VW+L + + + KE R
Sbjct: 96 KMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLE-------------IPKMKEETRD 142
Query: 440 LSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQG-GPYHDMLHSILGAYT 498
L S++++ G S R+ I LD++RTF + +F+ G L +L AY+
Sbjct: 143 LY---SKLKHRARGCSPDIRQ-----IDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAYS 194
Query: 499 CYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKP--CQMAFFRVDHGLMLTYFAA 556
Y +VGY QGMS I A+L++ ++ DAF A L + P FF +L +
Sbjct: 195 IYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQEH 254
Query: 557 FEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLF 616
E + L KL H + Y + W F + P L RIWD++ +GE L
Sbjct: 255 HEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVLT 314
Query: 617 RTALGILKLFEDILTKMDFIHMAQFLTR-LPEDLPAEELFASIATIQMQSRNKKWAQV 673
+ ILKL + L K+ + +F L +D E+ F I +Q+ K A++
Sbjct: 315 AMSYTILKLHKKHLMKLSMEELVEFFQETLAKDFFFEDDFV-IEQLQISMTELKRAKL 371
>gi|229577000 ecotropic viral integration site 5-like isoform 1
[Homo sapiens]
Length = 805
Score = 103 bits (256), Expect = 7e-22
Identities = 84/316 (26%), Positives = 142/316 (44%), Gaps = 41/316 (12%)
Query: 381 ILPNWETMWCSRK---VRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLAR---AK 434
I WE W RK +++L +GIP R VW L +C A K
Sbjct: 93 IANEWEE-WRRRKEKLLKELIRKGIPHHFRAIVWQL--------------LCSATDMPVK 137
Query: 435 ERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQ-QGGPYHDMLHSI 493
++ L S E +LI+ DI+RT+P F+ Q ++L ++
Sbjct: 138 NQYSELLKMSSPCE---------------KLIRRDIARTYPEHEFFKGQDSLGQEVLFNV 182
Query: 494 LGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTY 553
+ AY+ +VGY QG +FI +L++ + +AF F L+ + F+ +
Sbjct: 183 MKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLC 242
Query: 554 FAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEE 613
FE +E LP L HF+ + +Y W TL+ + PL +A R++D+F +G E
Sbjct: 243 IYQFEYMLQEQLPDLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLE 302
Query: 614 FLFRTALGILKLFEDILTKMDFIHMAQFLTR-LPE--DLPAEELFASIATIQMQSRNKKW 670
+FR L +L++ + L ++D M+Q+ R +P D ++L ++ + K
Sbjct: 303 IVFRVGLALLQVNQAELMQLDMEGMSQYFQRVIPHQFDSCPDKLVLKAYQVKYNPKKMKR 362
Query: 671 AQVLTALQKDSREMEK 686
+ A K S+EME+
Sbjct: 363 LEKEYAAMK-SKEMEE 377
>gi|21687020 ecotropic viral integration site 5-like isoform 2 [Homo
sapiens]
Length = 794
Score = 103 bits (256), Expect = 7e-22
Identities = 84/316 (26%), Positives = 142/316 (44%), Gaps = 41/316 (12%)
Query: 381 ILPNWETMWCSRK---VRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLAR---AK 434
I WE W RK +++L +GIP R VW L +C A K
Sbjct: 93 IANEWEE-WRRRKEKLLKELIRKGIPHHFRAIVWQL--------------LCSATDMPVK 137
Query: 435 ERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQ-QGGPYHDMLHSI 493
++ L S E +LI+ DI+RT+P F+ Q ++L ++
Sbjct: 138 NQYSELLKMSSPCE---------------KLIRRDIARTYPEHEFFKGQDSLGQEVLFNV 182
Query: 494 LGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTY 553
+ AY+ +VGY QG +FI +L++ + +AF F L+ + F+ +
Sbjct: 183 MKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLC 242
Query: 554 FAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEE 613
FE +E LP L HF+ + +Y W TL+ + PL +A R++D+F +G E
Sbjct: 243 IYQFEYMLQEQLPDLNTHFRSQSFHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLE 302
Query: 614 FLFRTALGILKLFEDILTKMDFIHMAQFLTR-LPE--DLPAEELFASIATIQMQSRNKKW 670
+FR L +L++ + L ++D M+Q+ R +P D ++L ++ + K
Sbjct: 303 IVFRVGLALLQVNQAELMQLDMEGMSQYFQRVIPHQFDSCPDKLVLKAYQVKYNPKKMKR 362
Query: 671 AQVLTALQKDSREMEK 686
+ A K S+EME+
Sbjct: 363 LEKEYAAMK-SKEMEE 377
>gi|114688046 TBC1 domain family, member 4 [Homo sapiens]
Length = 1298
Score = 98.6 bits (244), Expect = 2e-20
Identities = 76/325 (23%), Positives = 146/325 (44%), Gaps = 28/325 (8%)
Query: 335 RQQYEEMVVQAKKRELKEAQRRKKQLEERCRVEESIGNAVLTWNNEILPNWETMWCSRK- 393
R + E ++A + EL ++++ K EE ++ + ++TW+ ++L + C +
Sbjct: 855 RMEKENQKLEASRDEL-QSRKVKLDYEEVGACQKEV---LITWDKKLLNCRAKIRCDMED 910
Query: 394 VRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENEDAG 453
+ L +G+P S RG++W + + + H L ++ + D
Sbjct: 911 IHTLLKEGVPKSRRGEIWQF-LALQYRLRHRL------------------PNKQQPPDIS 951
Query: 454 FSAADRE--ASLELIKLDISRTFPNLCIFQ-QGGPYHDMLHSILGAYTCYRPDVGYVQGM 510
+ ++ A I +D+ RTFP F Q GP L ++L AY+ +VGY QG+
Sbjct: 952 YKELLKQLTAQQHAILVDLGRTFPTHPYFSVQLGPGQLSLFNLLKAYSLLDKEVGYCQGI 1011
Query: 511 SFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFA 570
SF+A VL+L++ AF L+ +R D + + L+
Sbjct: 1012 SFVAGVLLLHMSEEQAFEMLKFLMYDLGFRKQYRPDMMSLQIQMYQLSRLLHDYHRDLYN 1071
Query: 571 HFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDIL 630
H ++N ++P +Y W TL++ L R++D+ G E +F+ AL +L E ++
Sbjct: 1072 HLEENEISPSLYAAPWFLTLFASQFSLGFVARVFDIIFLQGTEVIFKVALSLLSSQETLI 1131
Query: 631 TKMD-FIHMAQFLTRLPEDLPAEEL 654
+ + F ++ +FL D+ E+
Sbjct: 1132 MECESFENIVEFLKNTLPDMNTSEM 1156
>gi|13994322 TBC1 domain family, member 10A [Homo sapiens]
Length = 508
Score = 95.1 bits (235), Expect = 2e-19
Identities = 63/251 (25%), Positives = 113/251 (45%), Gaps = 32/251 (12%)
Query: 380 EILPNWETMWCSR--KVRDLWWQGIPPSVRGKVWSLAIGNELNITH---ELFDICLARAK 434
++L NW+ + K+R +GIPPS+RG+ W G ++ + + ++ ++
Sbjct: 88 DMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELDMSPGD 147
Query: 435 ERWRSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIF-QQGGPYHDMLHSI 493
+W L++I+ D+ R FP +F +GG L +
Sbjct: 148 PKW-------------------------LDVIERDLHRQFPFHEMFVSRGGHGQQDLFRV 182
Query: 494 LGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTY 553
L AYT YRP+ GY Q + IAAVL++++ AF + K + + L
Sbjct: 183 LKAYTLYRPEEGYCQAQAPIAAVLLMHMPAEQAFWCLVQICEKYLPGYYSEKLEAIQLDG 242
Query: 554 FAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEE 613
F + ++ P H + + P +Y+ +W +S++LP R+WD+F +G +
Sbjct: 243 EILFSLL-QKVSPVAHKHLSRQKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDMFFCEGVK 301
Query: 614 FLFRTALGILK 624
+FR L +LK
Sbjct: 302 IIFRVGLVLLK 312
>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
Length = 808
Score = 91.7 bits (226), Expect = 2e-18
Identities = 69/256 (26%), Positives = 113/256 (44%), Gaps = 42/256 (16%)
Query: 380 EILPNWETMWCSR---KVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKER 436
++ NW+ W SR KV+ +GIP S+R K W
Sbjct: 337 DMFSNWDK-WLSRRFQKVKLRCRKGIPSSLRAKAWQY----------------------- 372
Query: 437 WRSLSTGGSEVENEDAGFSAADREAS----LELIKLDISRTFPNLCIFQ-QGGPYHDMLH 491
LS +E F +R L++I+ D+ R FP +F +GG L+
Sbjct: 373 ---LSNSKELLEQNPGKFEELERAPGDPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLY 429
Query: 492 SILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLML 551
IL AYT YRPD GY Q + +AAVL++++ AF + +K + + L
Sbjct: 430 RILKAYTIYRPDEGYCQAQAPVAAVLLMHMPAEQAFWCLVQICDKYLPGYYSAGLEAIQL 489
Query: 552 TYFAAFEVFF---EENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFC 608
E+FF P H ++ + P +Y+ +W +++++LP R+WD+F
Sbjct: 490 DG----EIFFALLRRASPLAHRHLRRQRIDPVLYMTEWFMCIFARTLPWASVLRVWDMFF 545
Query: 609 RDGEEFLFRTALGILK 624
+G + +FR AL +L+
Sbjct: 546 CEGVKIIFRVALVLLR 561
>gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
[Homo sapiens]
Length = 1168
Score = 89.4 bits (220), Expect = 1e-17
Identities = 76/356 (21%), Positives = 148/356 (41%), Gaps = 43/356 (12%)
Query: 305 DFEPLSTTALILEDRPANLPAKPAEEAQKH-RQQYEEMVVQAKKRELKEAQRRKKQLEER 363
+ P S + ED P P + + + R+ +++ ++Q E + +K Q E
Sbjct: 690 ELPPRSPLEPVCEDGPFGPPPEEKKRTSRELRELWQKAILQQILLLRMEKENQKLQASEN 749
Query: 364 CRVEESIG---NAVLTWNNEILPNWETMWCS----------RKVRDLWWQGIPPSVRGKV 410
+ + + + E+ WE M + K+ QG+P RG++
Sbjct: 750 DLLNKRLKLDYEEITPCLKEVTTVWEKMLSTPGRSKIKFDMEKMHSAVGQGVPRHHRGEI 809
Query: 411 WSLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLE--LIKL 468
W + + ++ H+ S+ + +D + ++ + + I +
Sbjct: 810 WKF-LAEQFHLKHQF------------------PSKQQPKDVPYKELLKQLTSQQHAILI 850
Query: 469 DISRTFPNLCIFQ-QGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAF 527
D+ RTFP F Q G L++IL AY+ +VGY QG+SF+A +L+L++ +AF
Sbjct: 851 DLGRTFPTHPYFSAQLGAGQLSLYNILKAYSLLDQEVGYCQGLSFVAGILLLHMSEEEAF 910
Query: 528 IAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWI 587
L+ +R D ++ + L+ H +++ + P +Y W
Sbjct: 911 KMLKFLMFDMGLRKQYRPDMIILQIQMYQLSRLLHDYHRDLYNHLEEHEIGPSLYAAPWF 970
Query: 588 FTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGIL-------KLFEDILTKMDFI 636
T+++ PL R++D+ G E +F+ AL +L E++ T +DFI
Sbjct: 971 LTMFASQFPLGFVARVFDMIFLQGTEVIFKVALSLLGSHKPLILQHENLETIVDFI 1026
>gi|38348348 TBC1 domain family, member 10C [Homo sapiens]
Length = 446
Score = 86.7 bits (213), Expect = 7e-17
Identities = 64/253 (25%), Positives = 110/253 (43%), Gaps = 34/253 (13%)
Query: 380 EILPNWETMWCSR--KVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERW 437
E+ +WE R KV+ +GIP ++R + W L G +C + +
Sbjct: 69 EMTSHWEKTMSRRYKKVKMQCRKGIPSALRARCWPLLCGAH---------VCQKNSPGTY 119
Query: 438 RSLSTGGSEVENEDAGFSAADREASLELIKLDISRTFP--NLCIFQQGGPYHDMLHSILG 495
+ L+ + + +E I D+ R FP + + QG +L +L
Sbjct: 120 QELAEAPGDPQ-------------WMETIGRDLHRQFPLHEMFVSPQGHGQQGLLQ-VLK 165
Query: 496 AYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQM---AFFRVDHGLMLT 552
AYT YRP+ GY Q +AAVL+++L +AF + C++ ++ +
Sbjct: 166 AYTLYRPEQGYCQAQGPVAAVLLMHLPPEEAFWCLVQI----CEVYLPGYYGPHMEAVRL 221
Query: 553 YFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGE 612
F LP + H ++ + P +YL +W L+++SLP R+WD F +G
Sbjct: 222 DAEVFMALLRRLLPHVHKHLQQVGVGPLLYLPEWFLCLFARSLPFPTVLRVWDAFLSEGA 281
Query: 613 EFLFRTALGILKL 625
LFR L +++L
Sbjct: 282 RVLFRVGLTLVRL 294
>gi|29648315 small G protein signaling modulator 3 [Homo sapiens]
Length = 749
Score = 85.5 bits (210), Expect = 2e-16
Identities = 69/271 (25%), Positives = 116/271 (42%), Gaps = 22/271 (8%)
Query: 391 SRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENE 450
S K+R L GIP +R ++W G A K+R LS E
Sbjct: 104 SEKLRSLVLAGIPHGMRPQLWMRLSG--------------ALQKKRNSELSY------RE 143
Query: 451 DAGFSAADREASLELIKLDISRTFP-NLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQG 509
S+ D + + I+ D+ RT P N C G L +L A P++GY QG
Sbjct: 144 IVKNSSNDETIAAKQIEKDLLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQG 203
Query: 510 MSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLF 569
+AA L+L L+ DAF S ++ ++F + T + LP+L
Sbjct: 204 TGMVAACLLLFLEEEDAFWMMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLD 263
Query: 570 AHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKL-FED 628
+++++ + + W T ++ + + L RIWD+F +G LF+ LG+L L E+
Sbjct: 264 KLLQEHDIELSLITLHWFLTAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEE 323
Query: 629 ILTKMDFIHMAQFLTRLPEDLPAEELFASIA 659
++ + + L+ +P + EL +A
Sbjct: 324 LIQSENSASIFNTLSDIPSQMEDAELLLGVA 354
>gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens]
Length = 963
Score = 82.8 bits (203), Expect = 1e-15
Identities = 64/255 (25%), Positives = 107/255 (41%), Gaps = 34/255 (13%)
Query: 388 MWCSRKVRDLWWQGIPPSVRGKVWSLAIGNEL-----NITHELFDICLARAKERWRSLST 442
M CS ++++L GIP R KVW + N F L +A E+ S
Sbjct: 649 MMCSPELKNLIRAGIPHEHRSKVWKWCVDRHTRKFKDNTEPGHFQTLLQKALEKQNPAS- 707
Query: 443 GGSEVENEDAGFSAADREASLELIKLDISRTFPN----LCIFQQGGPYHDMLHSILGAYT 498
+ I+LD+ RT PN C +G L ++L A++
Sbjct: 708 ---------------------KQIELDLLRTLPNNKHYSCPTSEG---IQKLRNVLLAFS 743
Query: 499 CYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFE 558
PD+GY QG++ + AV +L L+ DAF ++ ++ F
Sbjct: 744 WRNPDIGYCQGLNRLVAVALLYLEQEDAFWCLVTIVEVFMPRDYYTKTLLGSQVDQRVFR 803
Query: 559 VFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRT 618
E LP+L HF++ + + +W ++ S+ D+ +IWD F +G + +FR
Sbjct: 804 DLMSEKLPRLHGHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRF 863
Query: 619 ALGILKLFEDILTKM 633
AL + K E+ + K+
Sbjct: 864 ALALFKYKEEEILKL 878
>gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens]
Length = 914
Score = 82.8 bits (203), Expect = 1e-15
Identities = 64/255 (25%), Positives = 107/255 (41%), Gaps = 34/255 (13%)
Query: 388 MWCSRKVRDLWWQGIPPSVRGKVWSLAIGNEL-----NITHELFDICLARAKERWRSLST 442
M CS ++++L GIP R KVW + N F L +A E+ S
Sbjct: 649 MMCSPELKNLIRAGIPHEHRSKVWKWCVDRHTRKFKDNTEPGHFQTLLQKALEKQNPAS- 707
Query: 443 GGSEVENEDAGFSAADREASLELIKLDISRTFPN----LCIFQQGGPYHDMLHSILGAYT 498
+ I+LD+ RT PN C +G L ++L A++
Sbjct: 708 ---------------------KQIELDLLRTLPNNKHYSCPTSEG---IQKLRNVLLAFS 743
Query: 499 CYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFE 558
PD+GY QG++ + AV +L L+ DAF ++ ++ F
Sbjct: 744 WRNPDIGYCQGLNRLVAVALLYLEQEDAFWCLVTIVEVFMPRDYYTKTLLGSQVDQRVFR 803
Query: 559 VFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRT 618
E LP+L HF++ + + +W ++ S+ D+ +IWD F +G + +FR
Sbjct: 804 DLMSEKLPRLHGHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRF 863
Query: 619 ALGILKLFEDILTKM 633
AL + K E+ + K+
Sbjct: 864 ALALFKYKEEEILKL 878
>gi|226693407 TBC1 domain family, member 3H [Homo sapiens]
Length = 549
Score = 77.4 bits (189), Expect = 4e-14
Identities = 70/257 (27%), Positives = 112/257 (43%), Gaps = 26/257 (10%)
Query: 380 EILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRS 439
++L +WE SRK+ D ++G+P ++RG +WS+ LNI E +
Sbjct: 80 DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVL----LNI-------------EEMKL 122
Query: 440 LSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQ--GGPYHDMLHSILGAY 497
+ G ++ E S+ ++ I DIS T F+ G ++LH +L AY
Sbjct: 123 KNPGRYQIMKEKGKRSSEH----IQRIDRDISGTLRKHMFFRDRYGTKQRELLHILL-AY 177
Query: 498 TCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLL--NKPCQMAFFRVDHGLMLTYFA 555
Y P+VGY + +S IAA+ +L L DAF A LL + F + G +
Sbjct: 178 EEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQD 237
Query: 556 AFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFL 615
E + PK H K +L + + + + L L R+WDV+ +GE+ L
Sbjct: 238 QQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQAL 297
Query: 616 FRTALGILKLFEDILTK 632
K+ + LTK
Sbjct: 298 MPITRIAFKVQQKRLTK 314
>gi|157502205 TBC1 domain family, member 3G [Homo sapiens]
Length = 549
Score = 77.4 bits (189), Expect = 4e-14
Identities = 70/257 (27%), Positives = 112/257 (43%), Gaps = 26/257 (10%)
Query: 380 EILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRS 439
++L +WE SRK+ D ++G+P ++RG +WS+ LNI E +
Sbjct: 80 DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVL----LNI-------------EEMKL 122
Query: 440 LSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQ--GGPYHDMLHSILGAY 497
+ G ++ E S+ ++ I DIS T F+ G ++LH +L AY
Sbjct: 123 KNPGRYQIMKEKGKRSSEH----IQRIDRDISGTLRKHMFFRDRYGTKQRELLHILL-AY 177
Query: 498 TCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLL--NKPCQMAFFRVDHGLMLTYFA 555
Y P+VGY + +S IAA+ +L L DAF A LL + F + G +
Sbjct: 178 EEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQD 237
Query: 556 AFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFL 615
E + PK H K +L + + + + L L R+WDV+ +GE+ L
Sbjct: 238 QQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQAL 297
Query: 616 FRTALGILKLFEDILTK 632
K+ + LTK
Sbjct: 298 MPITRIAFKVQQKRLTK 314
>gi|183583565 TBC1 domain family, member 3 [Homo sapiens]
Length = 549
Score = 77.0 bits (188), Expect = 5e-14
Identities = 69/257 (26%), Positives = 112/257 (43%), Gaps = 26/257 (10%)
Query: 380 EILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRS 439
++L +WE SRK+ D ++G+P ++RG +WS+ LNI E +
Sbjct: 80 DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVL----LNI-------------EEMKL 122
Query: 440 LSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQ--GGPYHDMLHSILGAY 497
+ G ++ E S+ ++ I D+S T F+ G ++LH +L AY
Sbjct: 123 KNPGRYQIMKEKGKRSSEH----IQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILL-AY 177
Query: 498 TCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLL--NKPCQMAFFRVDHGLMLTYFA 555
Y P+VGY + +S IAA+ +L L DAF A LL + F + G +
Sbjct: 178 EEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQD 237
Query: 556 AFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFL 615
E + PK H K +L + + + + L L R+WDV+ +GE+ L
Sbjct: 238 QQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQAL 297
Query: 616 FRTALGILKLFEDILTK 632
K+ + LTK
Sbjct: 298 MPITRIAFKVQQKRLTK 314
>gi|183583567 TBC1 domain family, member 3E [Homo sapiens]
Length = 549
Score = 77.0 bits (188), Expect = 5e-14
Identities = 69/257 (26%), Positives = 112/257 (43%), Gaps = 26/257 (10%)
Query: 380 EILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRS 439
++L +WE SRK+ D ++G+P ++RG +WS+ LNI E +
Sbjct: 80 DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVL----LNI-------------EEMKL 122
Query: 440 LSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQ--GGPYHDMLHSILGAY 497
+ G ++ E S+ ++ I D+S T F+ G ++LH +L AY
Sbjct: 123 KNPGRYQIMKEKGKRSSEH----IQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILL-AY 177
Query: 498 TCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLL--NKPCQMAFFRVDHGLMLTYFA 555
Y P+VGY + +S IAA+ +L L DAF A LL + F + G +
Sbjct: 178 EEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQD 237
Query: 556 AFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFL 615
E + PK H K +L + + + + L L R+WDV+ +GE+ L
Sbjct: 238 QQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQAL 297
Query: 616 FRTALGILKLFEDILTK 632
K+ + LTK
Sbjct: 298 MPITRIAFKVQQKRLTK 314
>gi|183583563 TBC1 domain family, member 3D [Homo sapiens]
Length = 549
Score = 77.0 bits (188), Expect = 5e-14
Identities = 69/257 (26%), Positives = 112/257 (43%), Gaps = 26/257 (10%)
Query: 380 EILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRS 439
++L +WE SRK+ D ++G+P ++RG +WS+ LNI E +
Sbjct: 80 DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVL----LNI-------------EEMKL 122
Query: 440 LSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQ--GGPYHDMLHSILGAY 497
+ G ++ E S+ ++ I D+S T F+ G ++LH +L AY
Sbjct: 123 KNPGRYQIMKEKGKRSSEH----IQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILL-AY 177
Query: 498 TCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLL--NKPCQMAFFRVDHGLMLTYFA 555
Y P+VGY + +S IAA+ +L L DAF A LL + F + G +
Sbjct: 178 EEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQD 237
Query: 556 AFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFL 615
E + PK H K +L + + + + L L R+WDV+ +GE+ L
Sbjct: 238 QQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQAL 297
Query: 616 FRTALGILKLFEDILTK 632
K+ + LTK
Sbjct: 298 MPITRIAFKVQQKRLTK 314
>gi|14149985 TBC1 domain family, member 3F [Homo sapiens]
Length = 549
Score = 76.6 bits (187), Expect = 7e-14
Identities = 66/257 (25%), Positives = 110/257 (42%), Gaps = 26/257 (10%)
Query: 380 EILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRS 439
++L +WE SRK+ D ++G+P ++RG +WS+ + E +
Sbjct: 80 DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTE-----------------EMKL 122
Query: 440 LSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQ--GGPYHDMLHSILGAY 497
+ G ++ E S+ ++ I D+S T F+ G ++LH +L AY
Sbjct: 123 KNPGRYQIMKEKGKKSSEH----IQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILL-AY 177
Query: 498 TCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLL--NKPCQMAFFRVDHGLMLTYFA 555
Y P+VGY + +S IAA+ +L L DAF A LL + F + G +
Sbjct: 178 EEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQD 237
Query: 556 AFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFL 615
E + PK H K +L + + + + L L R+WDV+ +GE+ L
Sbjct: 238 QQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQAL 297
Query: 616 FRTALGILKLFEDILTK 632
K+ + LTK
Sbjct: 298 MPITRIAFKVQQKRLTK 314
>gi|90577185 TBC1 domain family member 3C [Homo sapiens]
Length = 549
Score = 74.3 bits (181), Expect = 3e-13
Identities = 69/257 (26%), Positives = 111/257 (43%), Gaps = 26/257 (10%)
Query: 380 EILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRS 439
++L +WE SRK+ D ++G+P ++RG +WS+ LNI E +
Sbjct: 80 DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVL----LNI-------------EEMKL 122
Query: 440 LSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQ--GGPYHDMLHSILGAY 497
+ G ++ E S+ ++ I DIS T F+ G ++LH +L AY
Sbjct: 123 KNPGRYQIMKEKGKRSSEH----IQRIDRDISGTLRKHMFFRDRYGTKQRELLHILL-AY 177
Query: 498 TCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLL--NKPCQMAFFRVDHGLMLTYFA 555
Y P+VGY + +S IAA+ +L L DAF A LL + F + G +
Sbjct: 178 EEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQD 237
Query: 556 AFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFL 615
E + K H K +L + + + + L L R+WDV+ +GE+ L
Sbjct: 238 QQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQAL 297
Query: 616 FRTALGILKLFEDILTK 632
K+ + LTK
Sbjct: 298 MPITRIAFKVQQKRLTK 314
>gi|38570101 TBC1 domain family, member 8B (with GRAM domain)
isoform a [Homo sapiens]
Length = 1120
Score = 73.2 bits (178), Expect = 8e-13
Identities = 67/261 (25%), Positives = 110/261 (42%), Gaps = 28/261 (10%)
Query: 387 TMWCSRKVRDLWWQGIPPSVRGKVWSLAIG--NELNITHELFDICLARAKERWRSLSTGG 444
+M+ ++K RDL +GIP ++RG++W L G N++ + +
Sbjct: 473 SMFRTKKTRDLVVRGIPETLRGELWMLFSGAVNDMATNPDYY------------------ 514
Query: 445 SEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDV 504
+EV + G + E I+ D+ R+ P FQ L +L AY P +
Sbjct: 515 TEVVEQSLGTC----NLATEEIERDLRRSLPEHPAFQSDTGI-SALRRVLTAYAYRNPKI 569
Query: 505 GYVQGMSFIAAVLILNLDTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEEN 564
GY Q M+ + +VL+L +AF + + F R G ++ A FE ++
Sbjct: 570 GYCQAMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNRRIIGALVDQ-AVFEELIRDH 628
Query: 565 LPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILK 624
LP+L H + L W TL+ LP++ A + D F DG + + + L IL
Sbjct: 629 LPQLTEHMTDMTFFSSVSL-SWFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAILD 687
Query: 625 L-FEDILTKMDFIHMAQFLTR 644
+ +LT D L R
Sbjct: 688 YNLDKLLTCKDDAEAVTALNR 708
>gi|149999613 TBC1 domain family, member 3B [Homo sapiens]
Length = 549
Score = 72.8 bits (177), Expect = 1e-12
Identities = 68/257 (26%), Positives = 110/257 (42%), Gaps = 26/257 (10%)
Query: 380 EILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRS 439
++L +WE SRK+ D ++G+P ++RG +WS+ LNI E +
Sbjct: 80 DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVL----LNI-------------EEMKL 122
Query: 440 LSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQQ--GGPYHDMLHSILGAY 497
+ G ++ E S+ ++ I DIS T F+ G ++LH +L AY
Sbjct: 123 KNPGRYQIMKEKGKRSSEH----IQRIDRDISGTLRKHMFFRDRYGTKQRELLHILL-AY 177
Query: 498 TCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLL--NKPCQMAFFRVDHGLMLTYFA 555
Y P+VGY + +S IAA+ +L DAF A LL + F + G +
Sbjct: 178 EEYNPEVGYCRDLSHIAALFLLYFPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQD 237
Query: 556 AFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFL 615
E + K H K +L + + + + L L R+WDV+ +GE+ L
Sbjct: 238 QQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQAL 297
Query: 616 FRTALGILKLFEDILTK 632
K+ + LTK
Sbjct: 298 MPITRIAFKVQQKRLTK 314
>gi|109638751 ubiquitin specific protease 6 [Homo sapiens]
Length = 1406
Score = 72.0 bits (175), Expect = 2e-12
Identities = 71/256 (27%), Positives = 108/256 (42%), Gaps = 24/256 (9%)
Query: 380 EILPNWETMWCSRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRS 439
E+L WET S K+ D ++GIP ++RG VWS+ LNI + +
Sbjct: 79 EMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVL----LNI-------------QEIKL 121
Query: 440 LSTGGSEVENEDAGFSAADREASLELIKLDISRTFPNLCIFQ-QGGPYHDMLHSILGAYT 498
+ G ++ E S+ + I LD+ T N F+ + G L IL AY+
Sbjct: 122 KNPGRYQIMKERGKRSS----EHIHHIDLDVRTTLRNHVFFRDRYGAKQRELFYILLAYS 177
Query: 499 CYRPDVGYVQGMSFIAAVLILNLDTADAFIAFSNLL--NKPCQMAFFRVDHGLMLTYFAA 556
Y P+VGY + +S I A+ +L L DAF A LL + F + G +
Sbjct: 178 EYNPEVGYCRDLSHITALFLLYLPEEDAFWALVQLLASERHSLPGFHSPNGGTVQGLQDQ 237
Query: 557 FEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLF 616
E ++ PK H K L + + + L L R+WDV+ +GE+ L
Sbjct: 238 QEHVVPKSQPKTMWHQDKEGLCGQCASLGCLLRNLIDGISLGLTLRLWDVYLVEGEQVLM 297
Query: 617 RTALGILKLFEDILTK 632
LK+ + L K
Sbjct: 298 PITSIALKVQQKRLMK 313
>gi|222352143 TBC1 domain family, member 2 [Homo sapiens]
Length = 917
Score = 67.0 bits (162), Expect = 6e-11
Identities = 64/297 (21%), Positives = 121/297 (40%), Gaps = 32/297 (10%)
Query: 391 SRKVRDLWWQGIPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENE 450
S +++ L G+P R +VW + L + H L T G E
Sbjct: 615 SAELKQLLRAGVPREHRPRVWRWLV--HLRVQH----------------LHTPGCYQELL 656
Query: 451 DAGFSAADREASLELIKLDISRTFPNLCIFQ-QGGPYHDMLHSILGAYTCYRPDVGYVQG 509
G A + I+LD++RTFPN F + D L +L A++ P +GY QG
Sbjct: 657 SRG--QAREHPAARQIELDLNRTFPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQG 714
Query: 510 MSFIAAVLILNLDTAD-AFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKL 568
++ +AA+ +L L+ + AF ++ ++ + E LP+L
Sbjct: 715 LNRLAAIALLVLEEEESAFWCLVAIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRL 774
Query: 569 FAHFKKNNLTPDIYLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFED 628
AH ++++ + +W +++ SL ++ R+WD F +G ++ + +
Sbjct: 775 MAHLGQHHVDLSLVTFNWFLVVFADSLISNILLRVWDAFLYEGTKYNEK----------E 824
Query: 629 ILTKMDFIHMAQFLTRLPEDLPAEELFASIATIQMQSRNKKWAQVLTALQKDSREME 685
IL + + + Q+L + + +IA M K + L + ++ E E
Sbjct: 825 ILRLQNGLEIYQYLRFFTKTISNSRKLMNIAFNDMNPFRMKQLRQLRMVHRERLEAE 881
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,154,381
Number of Sequences: 37866
Number of extensions: 1280117
Number of successful extensions: 6479
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 89
Number of HSP's successfully gapped in prelim test: 137
Number of HSP's that attempted gapping in prelim test: 5830
Number of HSP's gapped (non-prelim): 700
length of query: 693
length of database: 18,247,518
effective HSP length: 109
effective length of query: 584
effective length of database: 14,120,124
effective search space: 8246152416
effective search space used: 8246152416
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.