BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD subunit [Homo sapiens] (551 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 1177 0.0 gi|217035107 pre-mRNA cleavage factor I, 59 kDa subunit isoform ... 362 e-100 gi|209862881 pre-mRNA cleavage factor I, 59 kDa subunit isoform ... 361 e-100 gi|217035102 pre-mRNA cleavage factor I, 59 kDa subunit isoform ... 361 e-100 gi|160707881 formin 2 [Homo sapiens] 140 4e-33 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 135 1e-31 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 134 3e-31 gi|7706501 WW domain binding protein 11 [Homo sapiens] 120 2e-27 gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 120 3e-27 gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 120 3e-27 gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 119 9e-27 gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre... 112 1e-24 gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 110 4e-24 gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 108 1e-23 gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 108 1e-23 gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 108 1e-23 gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 108 1e-23 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 107 4e-23 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 107 4e-23 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 107 4e-23 gi|150417989 cyclin K isoform 1 [Homo sapiens] 106 6e-23 gi|119829187 alpha 1 type XVII collagen [Homo sapiens] 105 1e-22 gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 105 1e-22 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 104 2e-22 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 103 5e-22 gi|146134388 YLP motif containing 1 [Homo sapiens] 103 5e-22 gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] 102 7e-22 gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] 102 7e-22 gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 102 9e-22 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 101 2e-21 >gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD subunit [Homo sapiens] Length = 551 Score = 1177 bits (3046), Expect = 0.0 Identities = 551/551 (100%), Positives = 551/551 (100%) Query: 1 MADGVDHIDIYADVGEEFNQEAEYGGHDQIDLYDDVISPSANNGDAPEDRDYMDTLPPTV 60 MADGVDHIDIYADVGEEFNQEAEYGGHDQIDLYDDVISPSANNGDAPEDRDYMDTLPPTV Sbjct: 1 MADGVDHIDIYADVGEEFNQEAEYGGHDQIDLYDDVISPSANNGDAPEDRDYMDTLPPTV 60 Query: 61 GDDVGKGAAPNVVYTYTGKRIALYIGNLTWWTTDEDLTEAVHSLGVNDILEIKFFENRAN 120 GDDVGKGAAPNVVYTYTGKRIALYIGNLTWWTTDEDLTEAVHSLGVNDILEIKFFENRAN Sbjct: 61 GDDVGKGAAPNVVYTYTGKRIALYIGNLTWWTTDEDLTEAVHSLGVNDILEIKFFENRAN 120 Query: 121 GQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCNKQFLSQFEMQSRKTTQSGQM 180 GQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCNKQFLSQFEMQSRKTTQSGQM Sbjct: 121 GQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCNKQFLSQFEMQSRKTTQSGQM 180 Query: 181 SGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPP 240 SGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPP Sbjct: 181 SGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPP 240 Query: 241 LGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPV 300 LGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPV Sbjct: 241 LGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPV 300 Query: 301 PGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPA 360 PGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPA Sbjct: 301 PGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPA 360 Query: 361 FFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAEFEEIMNR 420 FFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAEFEEIMNR Sbjct: 361 FFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAEFEEIMNR 420 Query: 421 NRAISSSAISRAVSDASAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISSLQDCLHGI 480 NRAISSSAISRAVSDASAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISSLQDCLHGI Sbjct: 421 NRAISSSAISRAVSDASAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISSLQDCLHGI 480 Query: 481 ESKSYGSGSRRERSRERDHSRSREKSRRHKSRSRDRHDDYYRERSRERERHRDRDRDRDR 540 ESKSYGSGSRRERSRERDHSRSREKSRRHKSRSRDRHDDYYRERSRERERHRDRDRDRDR Sbjct: 481 ESKSYGSGSRRERSRERDHSRSREKSRRHKSRSRDRHDDYYRERSRERERHRDRDRDRDR 540 Query: 541 ERDREREYRHR 551 ERDREREYRHR Sbjct: 541 ERDREREYRHR 551 >gi|217035107 pre-mRNA cleavage factor I, 59 kDa subunit isoform 3 [Homo sapiens] Length = 462 Score = 362 bits (928), Expect = e-100 Identities = 244/554 (44%), Positives = 303/554 (54%), Gaps = 110/554 (19%) Query: 1 MADGVDHIDIYADVGEEFNQEAEYGGHDQIDLYDDVISPSANNGDAPEDRDYMDTLPPTV 60 M++GVD IDIYAD EEFNQ+ E+ DQIDLYDDV++ ++ D DR PP V Sbjct: 1 MSEGVDLIDIYAD--EEFNQDPEFNNTDQIDLYDDVLTATSQPSD---DRSSSTEPPPPV 55 Query: 61 GDDVG---KGAAPNVVYTYTG---KRIALYIGNLTWWTTDEDLTEAVHSLGVNDILEIKF 114 + P ++YTY+G +R A+Y+G+ +WWTTD+ L + + S+GV D++E+KF Sbjct: 56 RQEPSPKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKF 115 Query: 115 FENRANGQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCNKQFLSQFEMQSRKT 174 ENRANGQSKG+A V V SE S KL++LLP + L+G+ V P +Q LSQFE Q+RK Sbjct: 116 AENRANGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKR 175 Query: 175 TQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQ 234 PP SR + GR A P + P A PP P Sbjct: 176 I------------PPRAHSRDS-SDSADGR-----ATPSENLVPSSARVDKPPSVLPYFN 217 Query: 235 TPPR--PPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPL 292 PP P +G P PP PP PPPL+ + G PPPP + L P Sbjct: 218 RPPSALPLMGLPPPPIPP---------PPPLSS--SFGVPPPPPGIH------YQHLMPP 260 Query: 293 PPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPP 352 PP PP + PPPG PP P F P P +GPP P A Sbjct: 261 PPRLPPHLA--VPPPGAIPPALHLNP---AFFPPPNATVGPP---------PDTYMKASA 306 Query: 353 PAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEA 412 P H S GPPP + +SEA Sbjct: 307 PYNHHG--------------SRDSGPPP--------------------------STVSEA 326 Query: 413 EFEEIMNRNRAISSSAISRAVSDASAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISS 472 EFE+IM RNRAISSSAIS+AVS ASAGDY AIETL+TAI++IKQS+V+ D+RC+VLISS Sbjct: 327 EFEDIMKRNRAISSSAISKAVSGASAGDYSDAIETLLTAIAVIKQSRVANDERCRVLISS 386 Query: 473 LQDCLHGIESKSY-----GSGSR-RERSRERDHSRSREKSRRHKS--RSRDRHDDYYRER 524 L+DCLHGIE+KSY GS SR R RSRER SRSRE SRRH+ + DRHDDY++ER Sbjct: 387 LKDCLHGIEAKSYSVGASGSSSRKRHRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQER 446 Query: 525 SRERERHRDRDRDR 538 +RE ERHRDR+RDR Sbjct: 447 NREHERHRDRERDR 460 >gi|209862881 pre-mRNA cleavage factor I, 59 kDa subunit isoform 2 [Homo sapiens] Length = 471 Score = 361 bits (927), Expect = e-100 Identities = 245/554 (44%), Positives = 304/554 (54%), Gaps = 101/554 (18%) Query: 1 MADGVDHIDIYADVGEEFNQEAEYGGHDQIDLYDDVISPSANNGDAPEDRDYMDTLPPTV 60 M++GVD IDIYAD EEFNQ+ E+ DQIDLYDDV++ ++ D DR PP V Sbjct: 1 MSEGVDLIDIYAD--EEFNQDPEFNNTDQIDLYDDVLTATSQPSD---DRSSSTEPPPPV 55 Query: 61 GDDVG---KGAAPNVVYTYTG---KRIALYIGNLTWWTTDEDLTEAVHSLGVNDILEIKF 114 + P ++YTY+G +R A+Y+G+ +WWTTD+ L + + S+GV D++E+KF Sbjct: 56 RQEPSPKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKF 115 Query: 115 FENRANGQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCNKQFLSQFEMQSRKT 174 ENRANGQSKG+A V V SE S KL++LLP + L+G+ V P +Q LSQFE Q+RK Sbjct: 116 AENRANGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKR 175 Query: 175 TQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQ 234 G PP SR + GR A P + P A PP P Sbjct: 176 ECVRVPRG---GIPPRAHSRDS-SDSADGR-----ATPSENLVPSSARVDKPPSVLPYFN 226 Query: 235 TPPR--PPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPL 292 PP P +G P PP PP PPPL+ + G PPPP + L P Sbjct: 227 RPPSALPLMGLPPPPIPP---------PPPLSS--SFGVPPPPPGIH------YQHLMPP 269 Query: 293 PPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPP 352 PP PP + PPPG PP P F P P +GPP P A Sbjct: 270 PPRLPPHLA--VPPPGAIPPALHLNP---AFFPPPNATVGPP---------PDTYMKASA 315 Query: 353 PAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEA 412 P H S GPPP + +SEA Sbjct: 316 PYNHHG--------------SRDSGPPP--------------------------STVSEA 335 Query: 413 EFEEIMNRNRAISSSAISRAVSDASAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISS 472 EFE+IM RNRAISSSAIS+AVS ASAGDY AIETL+TAI++IKQS+V+ D+RC+VLISS Sbjct: 336 EFEDIMKRNRAISSSAISKAVSGASAGDYSDAIETLLTAIAVIKQSRVANDERCRVLISS 395 Query: 473 LQDCLHGIESKSY-----GSGSR-RERSRERDHSRSREKSRRHKS--RSRDRHDDYYRER 524 L+DCLHGIE+KSY GS SR R RSRER SRSRE SRRH+ + DRHDDY++ER Sbjct: 396 LKDCLHGIEAKSYSVGASGSSSRKRHRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQER 455 Query: 525 SRERERHRDRDRDR 538 +RE ERHRDR+RDR Sbjct: 456 NREHERHRDRERDR 469 >gi|217035102 pre-mRNA cleavage factor I, 59 kDa subunit isoform 1 [Homo sapiens] Length = 514 Score = 361 bits (927), Expect = e-100 Identities = 245/554 (44%), Positives = 304/554 (54%), Gaps = 101/554 (18%) Query: 1 MADGVDHIDIYADVGEEFNQEAEYGGHDQIDLYDDVISPSANNGDAPEDRDYMDTLPPTV 60 M++GVD IDIYAD EEFNQ+ E+ DQIDLYDDV++ ++ D DR PP V Sbjct: 44 MSEGVDLIDIYAD--EEFNQDPEFNNTDQIDLYDDVLTATSQPSD---DRSSSTEPPPPV 98 Query: 61 GDDVG---KGAAPNVVYTYTG---KRIALYIGNLTWWTTDEDLTEAVHSLGVNDILEIKF 114 + P ++YTY+G +R A+Y+G+ +WWTTD+ L + + S+GV D++E+KF Sbjct: 99 RQEPSPKPNNKTPAILYTYSGLRNRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKF 158 Query: 115 FENRANGQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCNKQFLSQFEMQSRKT 174 ENRANGQSKG+A V V SE S KL++LLP + L+G+ V P +Q LSQFE Q+RK Sbjct: 159 AENRANGQSKGYAEVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKR 218 Query: 175 TQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQ 234 G PP SR + GR A P + P A PP P Sbjct: 219 ECVRVPRG---GIPPRAHSRDS-SDSADGR-----ATPSENLVPSSARVDKPPSVLPYFN 269 Query: 235 TPPR--PPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPL 292 PP P +G P PP PP PPPL+ + G PPPP + L P Sbjct: 270 RPPSALPLMGLPPPPIPP---------PPPLSS--SFGVPPPPPGIH------YQHLMPP 312 Query: 293 PPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPP 352 PP PP + PPPG PP P F P P +GPP P A Sbjct: 313 PPRLPPHLA--VPPPGAIPPALHLNP---AFFPPPNATVGPP---------PDTYMKASA 358 Query: 353 PAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEA 412 P H S GPPP + +SEA Sbjct: 359 PYNHHG--------------SRDSGPPP--------------------------STVSEA 378 Query: 413 EFEEIMNRNRAISSSAISRAVSDASAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISS 472 EFE+IM RNRAISSSAIS+AVS ASAGDY AIETL+TAI++IKQS+V+ D+RC+VLISS Sbjct: 379 EFEDIMKRNRAISSSAISKAVSGASAGDYSDAIETLLTAIAVIKQSRVANDERCRVLISS 438 Query: 473 LQDCLHGIESKSY-----GSGSR-RERSRERDHSRSREKSRRHKS--RSRDRHDDYYRER 524 L+DCLHGIE+KSY GS SR R RSRER SRSRE SRRH+ + DRHDDY++ER Sbjct: 439 LKDCLHGIEAKSYSVGASGSSSRKRHRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQER 498 Query: 525 SRERERHRDRDRDR 538 +RE ERHRDR+RDR Sbjct: 499 NREHERHRDRERDR 512 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 140 bits (352), Expect = 4e-33 Identities = 94/208 (45%), Positives = 101/208 (48%), Gaps = 24/208 (11%) Query: 208 PGAVPGGDRFPGPAGPGG---PPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLA 264 P +PG P P PG PPPP P PP PPL PG PP PP PG +PPP Sbjct: 1044 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPP-P 1100 Query: 265 GPPNRGDRPPPPVLFPGQPFGQPPLGPLPPG---PPPPVPGYGPPPGPPPPQQG-PPPPP 320 P G PPPP+ PG G PP PLP PPPP+PG G PP PP P+ G PPPPP Sbjct: 1101 PLPGVGIPPPPPL--PGA--GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPP 1156 Query: 321 GPFPPRPPGPLGPPLTLAPPPHLPG---PPP------GAPPPAPHVNPAFFPPPTNSGMP 371 P PP P P + PPP LPG PPP G PPP P PPP GM Sbjct: 1157 LPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMG 1216 Query: 372 TSDSRGPP-PTDPYGRPPPYDRGDYGPP 398 + PP P G PPP GPP Sbjct: 1217 IPPAPAPPLPPPGTGIPPPPLLPVSGPP 1244 Score = 138 bits (348), Expect = 1e-32 Identities = 95/217 (43%), Positives = 103/217 (47%), Gaps = 27/217 (12%) Query: 189 PGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGG---PPPPFPAGQTPPRPPLGPPG 245 PG + P G G P +PG P P PG PPPP P PP PPL PG Sbjct: 949 PGAAIPPPPPLPGAGIP-LPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--PG 1005 Query: 246 PPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPG---PPPPVPG 302 PP PP PG +PPP P G PPPP+ PG G PP PLP PPPP+PG Sbjct: 1006 AGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPL--PGA--GIPPPPPLPGAGIPPPPPLPG 1060 Query: 303 YGPPPGPPPPQQG-PPPPPGPFPPRPPGPLGPPLTLAPPPHLPG---PPP------GAPP 352 G PP PP P G PPPPP P PP P P + PPP LPG PPP G PP Sbjct: 1061 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP 1120 Query: 353 PAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389 P P PPP +P + PPP G PPP Sbjct: 1121 PPPLPGAGIPPPPP---LPGAGIPPPPPLPRVGIPPP 1154 Score = 137 bits (346), Expect = 2e-32 Identities = 90/198 (45%), Positives = 97/198 (48%), Gaps = 26/198 (13%) Query: 208 PGAVPGGDRFPGPAGPGG---PPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLA 264 P +PG P P PG PPPP P PP PPL PG PP PP PG +PPP Sbjct: 978 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPP-P 1034 Query: 265 GPPNRGDRPPPPVLFPGQPFGQPPLGPLPPG---PPPPVPGYGPPPGPPPPQQG-PPPPP 320 P G PPPP+ PG G PP PLP PPPP+PG G PP PP P G PPPPP Sbjct: 1035 PLPGAGIPPPPPL--PGA--GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1090 Query: 321 GPFPPRPPGPLGPPLTLAPPPHLPG---PPP------GAPPPAPHVNPAFFPPPTNSGMP 371 P PP P P + + PPP LPG PPP G PPP P PPP +P Sbjct: 1091 LPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP---LP 1147 Query: 372 TSDSRGPPPTDPYGRPPP 389 PPP G PPP Sbjct: 1148 RVGIPPPPPLPGAGIPPP 1165 Score = 137 bits (346), Expect = 2e-32 Identities = 90/198 (45%), Positives = 97/198 (48%), Gaps = 26/198 (13%) Query: 208 PGAVPGGDRFPGPAGPGG---PPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLA 264 P +PG P P PG PPPP P PP PPL PG PP PP PG +PPP Sbjct: 1000 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPP-P 1056 Query: 265 GPPNRGDRPPPPVLFPGQPFGQPPLGPLPPG---PPPPVPGYGPPPGPPPPQQG-PPPPP 320 P G PPPP+ PG G PP PLP PPPP+PG G PP PP P G PPPPP Sbjct: 1057 PLPGAGIPPPPPL--PGA--GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPP 1112 Query: 321 GPFPPRPPGPLGPPLTLAPPPHLPG---PPP------GAPPPAPHVNPAFFPPPTNSGMP 371 P PP P P + PPP LPG PPP G PPP P PPP +P Sbjct: 1113 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPP---LP 1169 Query: 372 TSDSRGPPPTDPYGRPPP 389 + PPP G PPP Sbjct: 1170 GAGIPPPPPLPGVGIPPP 1187 Score = 136 bits (343), Expect = 4e-32 Identities = 89/198 (44%), Positives = 95/198 (47%), Gaps = 26/198 (13%) Query: 208 PGAVPGGDRFPGPAGPGG---PPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLA 264 P +PG P P PG PPPP P PP PPL G P PP P G PPPL Sbjct: 923 PPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPL- 981 Query: 265 GPPNRGDRPPPPVLFPGQPFGQPPLGPLPPG---PPPPVPGYGPPPGPPPPQQG-PPPPP 320 P G PPPP+ PG G PP PLP PPPP+PG G PP PP P G PPPPP Sbjct: 982 --PGAGIPPPPPL--PGA--GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1035 Query: 321 GPFPPRPPGPLGPPLTLAPPPHLPG---PPP------GAPPPAPHVNPAFFPPPTNSGMP 371 P PP P P + PPP LPG PPP G PPP P PPP +P Sbjct: 1036 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP---LP 1092 Query: 372 TSDSRGPPPTDPYGRPPP 389 + PPP G PPP Sbjct: 1093 GAGIPPPPPLPGVGIPPP 1110 Score = 130 bits (326), Expect = 4e-30 Identities = 94/230 (40%), Positives = 100/230 (43%), Gaps = 30/230 (13%) Query: 174 TTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPG-AVPGGDRFPGPAGPGGPPPPFPA 232 T S M G G PP P G P A+P G PPPP P Sbjct: 864 TESSSSMPGLGMVPPPPP------PLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPG 917 Query: 233 GQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPL 292 PP PPL PG P PP PG +PPP PP G PPP PG PP PL Sbjct: 918 AGIPPPPPL--PGAGILPLPPLPGAGIPPP---PPLPGAAIPPPPPLPGAGIPLPP--PL 970 Query: 293 PPG---PPPPVPGYGPPPGPPPPQQG-PPPPPGPFPPRPPGPLGPPLTLAPPPHLPG--- 345 P PPPP+PG G PP PP P G PPPPP P PP P P + PPP LPG Sbjct: 971 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1030 Query: 346 PPP------GAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389 PPP G PPP P PPP +P + PPP G PPP Sbjct: 1031 PPPPPLPGAGIPPPPPLPGAGIPPPPP---LPGAGIPPPPPLPGAGIPPP 1077 Score = 128 bits (321), Expect = 2e-29 Identities = 91/207 (43%), Positives = 100/207 (48%), Gaps = 24/207 (11%) Query: 208 PGAVPGGDRFPGPAGPG---GPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLA 264 P +PG P P PG PPPP P PP PPL PG PP PP PG +PPP Sbjct: 1088 PPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPP-- 1143 Query: 265 GPPNRGDRPPPPVLFPGQPFGQPPLGPLPPG---PPPPVPGYGPPPGPPPPQQG-PPPPP 320 P R PPPP L PG G PP PLP PPPP+PG G PP PP P G PPPPP Sbjct: 1144 PPLPRVGIPPPPPL-PGA--GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPP 1200 Query: 321 GP---FPPRPPGPLGPPLTLAPPPHLPGPPPGAPPP--APHVNPAFFPPPTNSGMPTSDS 375 P PP PP P G + AP P LP P G PPP P P P +S +PT Sbjct: 1201 LPGAGIPPPPPLP-GMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQV 1259 Query: 376 RG----PPPTDPYGRPPPYDRGDYGPP 398 G P P+ +G D+G P Sbjct: 1260 CGFLPPPLPSGLFGLGMNQDKGSRKQP 1286 Score = 105 bits (261), Expect = 1e-22 Identities = 77/203 (37%), Positives = 87/203 (42%), Gaps = 45/203 (22%) Query: 227 PPPFPAGQTPPRPPLGPPGPPGPPGPPPPG--------------------QVLPPPLAGP 266 PPP P ++ P G PP PP PG ++LPPP Sbjct: 858 PPPLPCTESSSSMP--GLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL 915 Query: 267 PNRGDRPPPPV----LFPGQPF---GQPPLGPLPPG---PPPPVPGYGPPPGPPPPQQG- 315 P G PPPP+ + P P G PP PLP PPPP+PG G P PP P G Sbjct: 916 PGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGI 975 Query: 316 PPPPPGPFPPRPPGPLGPPLTLAPPPHLPG---PPP------GAPPPAPHVNPAFFPPPT 366 PPPPP P PP P P + PPP LPG PPP G PPP P PPP Sbjct: 976 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1035 Query: 367 NSGMPTSDSRGPPPTDPYGRPPP 389 +P + PPP G PPP Sbjct: 1036 ---LPGAGIPPPPPLPGAGIPPP 1055 Score = 94.7 bits (234), Expect = 2e-19 Identities = 79/234 (33%), Positives = 86/234 (36%), Gaps = 75/234 (32%) Query: 228 PPFPAGQTPPRPPLGPPGPPGPPGPPPPGQV-----------------------LPPPL- 263 P Q PP P L G PG PP + PPPL Sbjct: 803 PTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLP 862 Query: 264 -----AGPPNRGDRPPPPVLFPGQPFGQPPLGPLP-----------PGPPPPVPGYGPPP 307 + P G PPPP PG P +P P PPPP+PG G PP Sbjct: 863 CTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPP 922 Query: 308 GPPPPQQG------------PPPPPGP---FPPRPP-----GPLGPPLT---LAPPPHLP 344 PP P G PPPPP P PP PP PL PPL + PPP LP Sbjct: 923 PPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLP 982 Query: 345 G---PPP------GAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389 G PPP G PPP P PPP +P + PPP G PPP Sbjct: 983 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP---LPGAGIPPPPPLPGAGIPPP 1033 Score = 44.3 bits (103), Expect = 3e-04 Identities = 66/255 (25%), Positives = 82/255 (32%), Gaps = 41/255 (16%) Query: 161 KQFLSQFEMQSRKTTQSGQMSG-EGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFP- 218 +Q Q ++Q ++ Q Q+ G E A PP A PQ PGA G DRF Sbjct: 207 QQQQQQLQLQLQQQQQQQQLQGAEEPAAPP----TAVSPQ--------PGAFLGLDRFLL 254 Query: 219 GPAGPGGPPPPFPAGQ--------------TPPRPPLGPPGPPGPPGPPPPGQVLPPPLA 264 GP+G G P P + PR P PP P G P P P A Sbjct: 255 GPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAA 314 Query: 265 GPPNRGDRPPPPVLFPG-QPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPF 323 P P PG + G P G + P P ++ P Sbjct: 315 KDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDA 374 Query: 324 PPR--------PPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTN--SGMPTS 373 P R GP P A P P P P P + P + T S S Sbjct: 375 PQRLGEEPEEEAQGPDAP--AAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHS 432 Query: 374 DSRGPPPTDPYGRPP 388 S+ P + R P Sbjct: 433 PSQSPNQSPRIKRRP 447 Score = 29.3 bits (64), Expect = 9.8 Identities = 23/87 (26%), Positives = 31/87 (35%), Gaps = 13/87 (14%) Query: 316 PPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAP------------PPAPHVNPAF-F 362 P PP P+P LG L P G PG+P P + P Sbjct: 232 PAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQ 291 Query: 363 PPPTNSGMPTSDSRGPPPTDPYGRPPP 389 PP+ G+P S++ P P + P Sbjct: 292 QPPSPGGLPVSEAPSLPAAQPAAKDSP 318 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 135 bits (339), Expect = 1e-31 Identities = 96/250 (38%), Positives = 105/250 (42%), Gaps = 41/250 (16%) Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP--PPFPAG---QTP 236 G+ + PP G ++ PQG G+ G P GD+ P P G P PP G Q P Sbjct: 55 GKPQGPPPQGGNK---PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP 111 Query: 237 PRPPLGPPGPPG-----PPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGP 291 P PP P GPP P GPPPPG+ PP G +R R PP G+P G PP G Sbjct: 112 PPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPP-----GKPQGPPPQGG 166 Query: 292 LPPGPPPPVPG--YGPPPGPPPPQQGPPPPPGPFPPRPPG------------PLGPPLTL 337 P PPP PG GPPP QGPPPP P P P G P GPP Sbjct: 167 NQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQG 226 Query: 338 APPPHLPGPPPGAP--PPAPHVNPAFFPPPTN-------SGMPTSDSRGPPPTDPYGRPP 388 P P PPPG P PP N PPP G S S PP P G P Sbjct: 227 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQ 286 Query: 389 PYDRGDYGPP 398 GPP Sbjct: 287 QEGNNPQGPP 296 Score = 132 bits (332), Expect = 8e-31 Identities = 98/256 (38%), Positives = 106/256 (41%), Gaps = 53/256 (20%) Query: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG---PGGPPPPFPAGQTPP----RPP 240 PP G + PQG + R P + PG + P P G P GPPPP Q PP P Sbjct: 72 PPPGKPQGPPPQGDKSRS--PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRP 129 Query: 241 LGPPGPPGPPGPPPPGQVL-----PP--PLAGPPNRGDRPPPPVLFPGQPFGQPPLG-PL 292 GPP P P GPPP G PP P PP G++P P PG+P G PP G Sbjct: 130 QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKK 189 Query: 293 PPGPPPPVPGYGPPP----------------GPPPP----QQGPPPPPG----------- 321 P GPPPP GPPP GPPP QGPPPPPG Sbjct: 190 PQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 249 Query: 322 -PFPPRPPG-PLGPPLTLAPPPHLPGPPPGAP--PPAPHVNPAFFPPPTNSGMPTSDSRG 377 P P PPG P GPP PPG P PP N PPP G P + Sbjct: 250 KPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNP-QQPQA 308 Query: 378 PPPTDPYGRPPPYDRG 393 PP P G P P G Sbjct: 309 PPAGQPQGPPRPPQGG 324 Score = 127 bits (319), Expect = 3e-29 Identities = 91/229 (39%), Positives = 99/229 (43%), Gaps = 50/229 (21%) Query: 208 PGAVPGGDRFPGPAG---PGGPPPPFPAGQTPPRPPLGPPGPPG--PPGPPPPGQVLPPP 262 P + G + P P G P GPPPP P P GPP G P GPPPPG+ PP Sbjct: 29 PSLIAGNPQGPSPQGGNKPQGPPPP-------PGKPQGPPPQGGNKPQGPPPPGKPQGPP 81 Query: 263 LAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPG--YGPPP-------GPPPP- 312 G +R R PP G+P G PP G P PPP PG GPPP GPPPP Sbjct: 82 PQGDKSRSPRSPP-----GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPG 136 Query: 313 -QQGPPP--PPGPFPPRPPG-PLGPPLTLAPPPHLPGPPPG---APPPAPHVNPAFFPPP 365 QGPPP P PPG P GPP P P PPPG PPP P PPP Sbjct: 137 KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPP 196 Query: 366 -------------TNSGMPTSDSRGPPP---TDPYGRPPPYDRGDYGPP 398 +S P +GPPP P G PPP + PP Sbjct: 197 GKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 245 Score = 120 bits (301), Expect = 3e-27 Identities = 87/229 (37%), Positives = 99/229 (43%), Gaps = 35/229 (15%) Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP--PPFPAG---QTP 236 G+ + PP G +R PQG G+ G P GD+ P P G P PP G Q P Sbjct: 116 GKPQGPPPQGGNR---PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP 172 Query: 237 PRPPLGPPGPPG-----PPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGP 291 P PP P GPP P GPPPPG+ PP G +R + PP G+P G PP G Sbjct: 173 PPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPP-----GKPQGPPPQGG 227 Query: 292 LPPGPPPPVPG--YGPPP-------GPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPH 342 P PPP PG GPPP GPPPP + P PP + PP PP Sbjct: 228 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK-PQGPPAQGGSKSQSARSPPGKPQGPPQ 286 Query: 343 LPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP--PP 389 G P PPP PA P P +GPP GRP PP Sbjct: 287 QEGNNPQGPPP-----PAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 330 Score = 65.5 bits (158), Expect = 1e-10 Identities = 54/144 (37%), Positives = 56/144 (38%), Gaps = 34/144 (23%) Query: 276 PVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPG---PFPPRPPG-PL 331 P L G P G P G P PPP PPG P PPP G P P PPG P Sbjct: 29 PSLIAGNPQGPSPQGGNKPQGPPP------PPGKP----QGPPPQGGNKPQGPPPPGKPQ 78 Query: 332 GPP-------LTLAPPPHLPGPP------PGAPPPAPHVNPAFFPPPTNSGMPTSDSRGP 378 GPP +PP GPP P PPP P PPP P P Sbjct: 79 GPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG--PPPQGGNRPQGP---P 133 Query: 379 PPTDPYGRPPPYD--RGDYGPPGR 400 PP P G PP D R PPG+ Sbjct: 134 PPGKPQGPPPQGDKSRSPRSPPGK 157 Score = 32.7 bits (73), Expect = 0.89 Identities = 26/78 (33%), Positives = 31/78 (39%), Gaps = 16/78 (20%) Query: 334 PLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPP---TDPYGRPPPY 390 P +A P P P G P P PPP G P +GPPP P G PPP Sbjct: 29 PSLIAGNPQGPSPQGGNKPQGP-------PPPP--GKP----QGPPPQGGNKPQGPPPPG 75 Query: 391 DRGDYGPPGREMDTARTP 408 P G + + R+P Sbjct: 76 KPQGPPPQGDKSRSPRSP 93 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 134 bits (336), Expect = 3e-31 Identities = 97/245 (39%), Positives = 107/245 (43%), Gaps = 41/245 (16%) Query: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG---PGGPPPPFPAGQTPP----RPP 240 PP G + PQG + R P + PG + P P G P GPPPP Q PP P Sbjct: 93 PPPGKPQGPPPQGDKSRS--PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 150 Query: 241 LGPPGPPGPPGPPPPGQVL------PP--PLAGPPNRGDRPPPPVLFPGQPFGQPPLGP- 291 GPP P P GPPP G PP P PP G++P P PG+P G PP G Sbjct: 151 QGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 210 Query: 292 LPPGPPPPVPGYGPPP----------GPPPPQQGPPP-----PPGPFPPRPPGPLGPPLT 336 P GPPPP GPPP PP QGPPP P GP PP P P GPP Sbjct: 211 KPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGP-PPPPGKPQGPPPQ 269 Query: 337 LAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPP---TDPYGRPPPYDRG 393 P P PPPG P P P +S P +GPPP P G PPP + Sbjct: 270 GGNKPQGP-PPPGKPQGPP---PQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP 325 Query: 394 DYGPP 398 PP Sbjct: 326 QGPPP 330 Score = 131 bits (329), Expect = 2e-30 Identities = 103/276 (37%), Positives = 114/276 (41%), Gaps = 72/276 (26%) Query: 191 GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG---PGGPPPPFPAGQTPP----RPPLGP 243 G+ + A PQGG + + P + PG + P P G P GPPPP Q PP P GP Sbjct: 34 GNPQGAPPQGGN-KPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 92 Query: 244 PGPPGPPGPPPPGQVL-----PP--PLAGPPNRGDRPPPPVLFPGQPFGQPPLGP-LPPG 295 P P P GPPP G PP P PP G++P P PG+P G PP G P G Sbjct: 93 PPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 152 Query: 296 PPPPVPGYGPPP-----------------GPPPP----QQGPPPPPG------------P 322 PPPP GPPP GPPP QGPPPPPG P Sbjct: 153 PPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 212 Query: 323 FPPRPPG-PLGPP--------LTLAPPPHLPGPPPGA------PPPAPHVNPAFFPPPTN 367 P PPG P GPP +PP GPPP PPP P PPP Sbjct: 213 QGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQG--PPPQG 270 Query: 368 SGMPTSDSRGPPPTDPYGRPP---PYDRGDYGPPGR 400 P PPP P G PP R PPG+ Sbjct: 271 GNKPQGP---PPPGKPQGPPPQGGSKSRSSRSPPGK 303 Score = 130 bits (326), Expect = 4e-30 Identities = 95/246 (38%), Positives = 100/246 (40%), Gaps = 40/246 (16%) Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG---PGGPPPPFPAGQTPP- 237 G GPP P G + R + PG + P P G P GPPPP Q PP Sbjct: 147 GNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 206 Query: 238 ---RPPLGPPGPPGPPGPPPPGQ-----VLPPP--LAGPPNRGDR----PPPPVLFPGQP 283 P GPP P P GPPP G PP GPP +G PPPP PG+P Sbjct: 207 QGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPP---PGKP 263 Query: 284 FGQPPL-GPLPPGPPPPVPGYGPPP----------GPPPPQQGPPPPPGPFPPRPPGPLG 332 G PP G P GPPPP GPPP PP QGPPP G P PP P G Sbjct: 264 QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPG 323 Query: 333 PPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDR 392 P PPP P G PPP P PP G S S PP P G P Sbjct: 324 KP--QGPPPQGGNKPQGPPPPGKPQGP---PP---QGGSKSRSARSPPGKPQGPPQQEGN 375 Query: 393 GDYGPP 398 GPP Sbjct: 376 NPQGPP 381 Score = 119 bits (297), Expect = 9e-27 Identities = 96/238 (40%), Positives = 106/238 (44%), Gaps = 51/238 (21%) Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG--PGGPPPPFPAG----QT 235 G+ + PP G ++ PQG G+ G P GD A PG P P P G Q Sbjct: 199 GKPQGPPPQGGNK---PQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQG 255 Query: 236 PPRPPLGPPGPPG-----PPGPPPPGQVL-PPPLAGPPNRGDRPPPPVLFPGQPFGQPPL 289 PP PP P GPP P GPPPPG+ PPP G +R R PP G+P G PP Sbjct: 256 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPP-----GKPQGPPPQ 310 Query: 290 GPLPPGPPPPVPG--YGPPP-------GPPPPQQGP--PPPPGPFPPR----PPG-PLGP 333 G P PPP PG GPPP GPPPP + P PPP G R PPG P GP Sbjct: 311 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK-PQGPPPQGGSKSRSARSPPGKPQGP 369 Query: 334 PLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP--PP 389 P P P PP G P P PA G P +GPP GRP PP Sbjct: 370 PQQEGNNPQGPPPPAGGNPQQPQAPPA--------GQP----QGPPRPPQGGRPSRPP 415 Score = 115 bits (289), Expect = 8e-26 Identities = 93/240 (38%), Positives = 99/240 (41%), Gaps = 60/240 (25%) Query: 208 PGAVPGGDRFPGPAGPGGPP-PPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLA-- 264 P + G + P G P PP P G+ PP G P GPP PPP PPP Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPP-PPPGKPQGPPPQGGN 87 Query: 265 ------------GPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPG--YGPPP--- 307 GPP +GD+ P PG+P G PP G P PPP PG GPPP Sbjct: 88 KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 147 Query: 308 ----GPPPP--QQGPPP-----------PPG-PFPPRPPG---PLGPPLTLAPPPHLP-G 345 GPPPP QGPPP PPG P P P G P GPP PPP P G Sbjct: 148 NKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPP----PPPGKPQG 203 Query: 346 PPP-------GAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPP 398 PPP G PPP P PP G S S PP P G PP GPP Sbjct: 204 PPPQGGNKPQGPPPPGKPQGP---PP---QGDNKSQSARSPPGKPQGPPPQGGNQPQGPP 257 Score = 101 bits (251), Expect = 2e-21 Identities = 72/180 (40%), Positives = 75/180 (41%), Gaps = 36/180 (20%) Query: 228 PPFPAGQTPPRPPLG---PPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPF 284 P AG PP G P GPP PPG P PPP G N+ PPPP PG+P Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQG----PPPQGG--NQPQGPPPP---PGKPQ 79 Query: 285 GQPPLGP-LPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHL 343 G PP G P GPPPP G P GPPP P P P P GPP P Sbjct: 80 GPPPQGGNKPQGPPPP----GKPQGPPPQGDKSRSPRSP----PGKPQGPPPQGGNQPQG 131 Query: 344 PGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYD---RGDYGPPGR 400 P PPPG P PPP P PPP P G PP D R PPG+ Sbjct: 132 PPPPPGKPQG---------PPPQGGNKPQGP---PPPGKPQGPPPQGDNKSRSSRSPPGK 179 Score = 48.1 bits (113), Expect = 2e-05 Identities = 38/109 (34%), Positives = 42/109 (38%), Gaps = 32/109 (29%) Query: 304 GPPPGPPPPQQGPPPPPGPFPPRPPG-PLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFF 362 G P G PP QG P GP P PPG P GPP P P PPPG P Sbjct: 34 GNPQGAPP--QGGNKPQGP--PSPPGKPQGPPPQGGNQPQGPPPPPGKP----------- 78 Query: 363 PPPTNSGMPTSDSRGPPP---TDPYGRPPPYDRGDYGPPGREMDTARTP 408 +GPPP P G PPP P G + + R+P Sbjct: 79 -------------QGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP 114 >gi|7706501 WW domain binding protein 11 [Homo sapiens] Length = 641 Score = 120 bits (302), Expect = 2e-27 Identities = 82/163 (50%), Positives = 89/163 (54%), Gaps = 20/163 (12%) Query: 208 PGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPG--PPGPPPPGQVLPPPLAG 265 P +VP + P PG PPP P PP PPL PPGPP PPGPPP PP L Sbjct: 394 PQSVPPS-QIQAPPMPG-PPPLGP----PPAPPLRPPGPPTGLPPGPPPGA---PPFLRP 444 Query: 266 PPNRGDRPP-PPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFP 324 P G R P P +L PG P G+PP GP PGPPP +P GPPP PPP+ PP PPG P Sbjct: 445 PGMPGLRGPLPRLLPPGPPPGRPP-GPP-PGPPPGLPP-GPPPRGPPPRLPPPAPPGIPP 501 Query: 325 PRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTN 367 PR PG + PPL P L PPG PPAP NP P N Sbjct: 502 PR-PGMMRPPLV----PPLGPAPPGLFPPAPLPNPGVLSAPPN 539 Score = 110 bits (276), Expect = 3e-24 Identities = 69/152 (45%), Positives = 75/152 (49%), Gaps = 17/152 (11%) Query: 249 PPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPP----PPVPGY- 303 PP PP Q+ PP+ GPP G P PP+ PG P G PP GP P PP P +PG Sbjct: 393 PPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPP-GPPPGAPPFLRPPGMPGLR 451 Query: 304 GP-----PPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGP-PPGAPPPAPHV 357 GP PPGPPP + P PPPGP P PPGP PP PPP LP P PPG PPP P + Sbjct: 452 GPLPRLLPPGPPPGRP-PGPPPGPPPGLPPGP--PPR--GPPPRLPPPAPPGIPPPRPGM 506 Query: 358 NPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389 PP P P P PP Sbjct: 507 MRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPP 538 Score = 98.6 bits (244), Expect = 1e-20 Identities = 74/188 (39%), Positives = 83/188 (44%), Gaps = 20/188 (10%) Query: 165 SQFEMQSRKT-TQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGP 223 S+ E QS+K + G A + + P PG P G P P Sbjct: 364 SEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRP 423 Query: 224 GGPPPPFPAGQTPPRPP-LGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQ 282 GPP P G P PP L PPG PG GP P ++LPP GPP PPP PG Sbjct: 424 PGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLP--RLLPP---GPPPGRPPGPPPGPPPGL 478 Query: 283 PFGQPPLGP-------LPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPL 335 P G PP GP PPG PPP PG PP PP P PPG F PP PL P Sbjct: 479 PPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPL---GPAPPGLF---PPAPLPNPG 532 Query: 336 TLAPPPHL 343 L+ PP+L Sbjct: 533 VLSAPPNL 540 Score = 62.8 bits (151), Expect = 8e-10 Identities = 43/92 (46%), Positives = 44/92 (47%), Gaps = 9/92 (9%) Query: 313 QQGPPP--PPGPF--PPRP-PGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTN 367 QQ PP PP PP P P PLGPP APP PGPP G PP P P F PP Sbjct: 390 QQAPPQSVPPSQIQAPPMPGPPPLGPP--PAPPLRPPGPPTGLPPGPPPGAPPFLRPPGM 447 Query: 368 SGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPG 399 G+ R PP P GRPP G PPG Sbjct: 448 PGLRGPLPRLLPPGPPPGRPPGPPPGP--PPG 477 Score = 51.6 bits (122), Expect = 2e-06 Identities = 39/97 (40%), Positives = 40/97 (41%), Gaps = 20/97 (20%) Query: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGP-PPPFPAGQTPPRP-----PL 241 PPG P GR G PG PG P P GP PPP P G PPRP PL Sbjct: 459 PPG-------PPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPL 511 Query: 242 GPPGPPGPPGPPPPGQV-------LPPPLAGPPNRGD 271 PP P PPG PP + PP L P D Sbjct: 512 VPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADD 548 Score = 48.9 bits (115), Expect = 1e-05 Identities = 35/84 (41%), Positives = 39/84 (46%), Gaps = 20/84 (23%) Query: 327 PPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPP-TDPYG 385 PP + P APP +PGPPP PPPAP + P G PT GPPP P+ Sbjct: 393 PPQSVPPSQIQAPP--MPGPPPLGPPPAPPLRPP--------GPPTGLPPGPPPGAPPFL 442 Query: 386 RPP--PYDRGDY-------GPPGR 400 RPP P RG PPGR Sbjct: 443 RPPGMPGLRGPLPRLLPPGPPPGR 466 Score = 43.9 bits (102), Expect = 4e-04 Identities = 28/64 (43%), Positives = 30/64 (46%), Gaps = 12/64 (18%) Query: 250 PGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGP 309 PG PP + GPP R P +L G P LPPG PP GPPPGP Sbjct: 159 PGAQPPSILKKTSAYGPPTRAVSILP-LLGHGVP-------RLPPGRKPP----GPPPGP 206 Query: 310 PPPQ 313 PPPQ Sbjct: 207 PPPQ 210 Score = 35.8 bits (81), Expect = 0.10 Identities = 26/77 (33%), Positives = 32/77 (41%), Gaps = 11/77 (14%) Query: 247 PGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLG----PLPPGPPPPVPG 302 P P P P +L + P + PP +L +G P PL P +P Sbjct: 140 PLPDMPHAPSNILIQDIPLPGAQ----PPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP 195 Query: 303 YGPPPGPPPPQQGPPPP 319 PPGPPP GPPPP Sbjct: 196 GRKPPGPPP---GPPPP 209 Score = 35.8 bits (81), Expect = 0.10 Identities = 20/54 (37%), Positives = 24/54 (44%), Gaps = 18/54 (33%) Query: 291 PLPPGPPPPV----PGYGPP--------------PGPPPPQQGPPPPPGPFPPR 326 PLP PP + YGPP P PP ++ P PPPGP PP+ Sbjct: 157 PLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQ 210 Score = 33.5 bits (75), Expect = 0.52 Identities = 24/78 (30%), Positives = 30/78 (38%), Gaps = 16/78 (20%) Query: 335 LTLAPPPHLPG-------PPPGAPPPAPHVNPAFFPPPTNS---------GMPTSDSRGP 378 + L PH P P PGA PP+ + + PPT + G+P Sbjct: 139 IPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRK 198 Query: 379 PPTDPYGRPPPYDRGDYG 396 PP P G PPP YG Sbjct: 199 PPGPPPGPPPPQVVQMYG 216 Score = 32.7 bits (73), Expect = 0.89 Identities = 22/47 (46%), Positives = 24/47 (51%), Gaps = 10/47 (21%) Query: 233 GQTPPRPPLG--PPGPPGPPGPPPP------GQVLPPPLAGPPNRGD 271 G PR P G PPGPP PGPPPP G+ + L PP R D Sbjct: 187 GHGVPRLPPGRKPPGPP--PGPPPPQVVQMYGRKVGFALDLPPRRRD 231 Score = 30.8 bits (68), Expect = 3.4 Identities = 27/72 (37%), Positives = 29/72 (40%), Gaps = 19/72 (26%) Query: 223 PGGPPPPF---PAGQTPPR------PPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRP 273 PG PP + PP P LG P PPG PPG PPP GPP P Sbjct: 159 PGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPG---PPP--GPP-----P 208 Query: 274 PPPVLFPGQPFG 285 P V G+ G Sbjct: 209 PQVVQMYGRKVG 220 >gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] Length = 1263 Score = 120 bits (301), Expect = 3e-27 Identities = 87/196 (44%), Positives = 91/196 (46%), Gaps = 38/196 (19%) Query: 211 VPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGP-PG------PP--PPGQVLPP 261 VP PG +G PPPP P T P PP PP PP P PG PP P G + P Sbjct: 573 VPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISP 632 Query: 262 PLAGPPNRGDR--PPPPVLFPGQPFGQPPLGPLPPG----PPPPVPGYGPPPGPPPPQQG 315 P PP GD PPPP L G G P LP G PPPP+PG P PPPP G Sbjct: 633 P---PPLSGDATIPPPPPLPEG--VGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPG 687 Query: 316 P---PPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHV-NPAFFPPPTNSGMP 371 PPPP P P G G P PPP LPG PG PPP P P PPP GMP Sbjct: 688 SAGIPPPPPPLP----GEAGMP---PPPPPLPG-GPGIPPPPPFPGGPGIPPPPPGMGMP 739 Query: 372 TSDSRGPPPTDPYGRP 387 PPP +G P Sbjct: 740 ------PPPPFGFGVP 749 Score = 107 bits (266), Expect = 4e-23 Identities = 93/291 (31%), Positives = 117/291 (40%), Gaps = 31/291 (10%) Query: 110 LEIKFFENRANGQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCNKQFLSQFEM 169 L+++ + ++ + K L G S+K K++L + +T + + E Sbjct: 489 LQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELED 548 Query: 170 QSRKTTQSGQMSGEGKAGPPGGSSRAAFPQ-----GGRGRGRFPGAVPGGDRFPGPAGPG 224 + + +S PP SRA P G G P PG P P P Sbjct: 549 AKK---EMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPP 605 Query: 225 GPPP-PFPAGQTPPRPPLGPPGPPGPPGPPPPGQ-VLPPPLAGPPNRGDRPPPPVLFPGQ 282 PPP P P G PP P G P PP G +PPP P G P P PG Sbjct: 606 PPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPP--PPLPEGVGIPSPSSLPGG 663 Query: 283 PFGQPPLGPLP-----PGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTL 337 PP PLP P PPPP+PG P PPPP G P P PP P GP + Sbjct: 664 T-AIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGP-----GI 717 Query: 338 APPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPP 388 PPP PG PG PPP P + PPP G+P + P P+G P Sbjct: 718 PPPPPFPG-GPGIPPPPPGMGMP-PPPPFGFGVPAA------PVLPFGLTP 760 Score = 88.6 bits (218), Expect = 1e-17 Identities = 66/166 (39%), Positives = 70/166 (42%), Gaps = 26/166 (15%) Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG-PGG----PPPPFPAGQTP 236 G + PP S A P P +P G P P+ PGG PPPP P Sbjct: 627 GTAISPPPPLSGDATIPP--------PPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARI 678 Query: 237 PRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGP 296 P PP P PG G PPP PPPL P PPPP PG P G PP P P GP Sbjct: 679 PPPP---PPLPGSAGIPPP----PPPL---PGEAGMPPPPPPLPGGP-GIPPPPPFPGGP 727 Query: 297 --PPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPP 340 PPP PG G PP PP P P PF P P + L P Sbjct: 728 GIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLRRP 773 Score = 71.6 bits (174), Expect = 2e-12 Identities = 47/130 (36%), Positives = 55/130 (42%), Gaps = 15/130 (11%) Query: 283 PFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPH 342 P P P+PP PP P P PP P PPP P PP PP PL + ++ PP Sbjct: 564 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPS 623 Query: 343 LPGPPPGAPPPAPHVNPAFFPP----------PTNSGMPTSDSRGPPPTDPYGR----PP 388 LPG +PPP P A PP P+ S +P + PPP P PP Sbjct: 624 LPGGTAISPPP-PLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP 682 Query: 389 PYDRGDYGPP 398 P G G P Sbjct: 683 PPLPGSAGIP 692 Score = 35.8 bits (81), Expect = 0.10 Identities = 27/73 (36%), Positives = 31/73 (42%), Gaps = 8/73 (10%) Query: 340 PPHLPG--PPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRG--DY 395 PP +P P P A PP P + PPP G T+ PPP P PPP G Sbjct: 564 PPSVPSRAPVPPA-PPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPP---PPPLPGGVCIS 619 Query: 396 GPPGREMDTARTP 408 PP TA +P Sbjct: 620 SPPSLPGGTAISP 632 >gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] Length = 1272 Score = 120 bits (301), Expect = 3e-27 Identities = 87/196 (44%), Positives = 91/196 (46%), Gaps = 38/196 (19%) Query: 211 VPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGP-PG------PP--PPGQVLPP 261 VP PG +G PPPP P T P PP PP PP P PG PP P G + P Sbjct: 582 VPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISP 641 Query: 262 PLAGPPNRGDR--PPPPVLFPGQPFGQPPLGPLPPG----PPPPVPGYGPPPGPPPPQQG 315 P PP GD PPPP L G G P LP G PPPP+PG P PPPP G Sbjct: 642 P---PPLSGDATIPPPPPLPEG--VGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPG 696 Query: 316 P---PPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHV-NPAFFPPPTNSGMP 371 PPPP P P G G P PPP LPG PG PPP P P PPP GMP Sbjct: 697 SAGIPPPPPPLP----GEAGMP---PPPPPLPG-GPGIPPPPPFPGGPGIPPPPPGMGMP 748 Query: 372 TSDSRGPPPTDPYGRP 387 PPP +G P Sbjct: 749 ------PPPPFGFGVP 758 Score = 107 bits (266), Expect = 4e-23 Identities = 93/291 (31%), Positives = 117/291 (40%), Gaps = 31/291 (10%) Query: 110 LEIKFFENRANGQSKGFALVGVGSEASSKKLMDLLPKRELHGQNPVVTPCNKQFLSQFEM 169 L+++ + ++ + K L G S+K K++L + +T + + E Sbjct: 498 LQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELED 557 Query: 170 QSRKTTQSGQMSGEGKAGPPGGSSRAAFPQ-----GGRGRGRFPGAVPGGDRFPGPAGPG 224 + + +S PP SRA P G G P PG P P P Sbjct: 558 AKK---EMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPP 614 Query: 225 GPPP-PFPAGQTPPRPPLGPPGPPGPPGPPPPGQ-VLPPPLAGPPNRGDRPPPPVLFPGQ 282 PPP P P G PP P G P PP G +PPP P G P P PG Sbjct: 615 PPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPP--PPLPEGVGIPSPSSLPGG 672 Query: 283 PFGQPPLGPLP-----PGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTL 337 PP PLP P PPPP+PG P PPPP G P P PP P GP + Sbjct: 673 T-AIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGP-----GI 726 Query: 338 APPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPP 388 PPP PG PG PPP P + PPP G+P + P P+G P Sbjct: 727 PPPPPFPG-GPGIPPPPPGMGMP-PPPPFGFGVPAA------PVLPFGLTP 769 Score = 88.6 bits (218), Expect = 1e-17 Identities = 66/166 (39%), Positives = 70/166 (42%), Gaps = 26/166 (15%) Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG-PGG----PPPPFPAGQTP 236 G + PP S A P P +P G P P+ PGG PPPP P Sbjct: 636 GTAISPPPPLSGDATIPP--------PPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARI 687 Query: 237 PRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGP 296 P PP P PG G PPP PPPL P PPPP PG P G PP P P GP Sbjct: 688 PPPP---PPLPGSAGIPPP----PPPL---PGEAGMPPPPPPLPGGP-GIPPPPPFPGGP 736 Query: 297 --PPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPP 340 PPP PG G PP PP P P PF P P + L P Sbjct: 737 GIPPPPPGMGMPPPPPFGFGVPAAPVLPFGLTPKKLYKPEVQLRRP 782 Score = 71.6 bits (174), Expect = 2e-12 Identities = 47/130 (36%), Positives = 55/130 (42%), Gaps = 15/130 (11%) Query: 283 PFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPH 342 P P P+PP PP P P PP P PPP P PP PP PL + ++ PP Sbjct: 573 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPS 632 Query: 343 LPGPPPGAPPPAPHVNPAFFPP----------PTNSGMPTSDSRGPPPTDPYGR----PP 388 LPG +PPP P A PP P+ S +P + PPP P PP Sbjct: 633 LPGGTAISPPP-PLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP 691 Query: 389 PYDRGDYGPP 398 P G G P Sbjct: 692 PPLPGSAGIP 701 Score = 35.8 bits (81), Expect = 0.10 Identities = 27/73 (36%), Positives = 31/73 (42%), Gaps = 8/73 (10%) Query: 340 PPHLPG--PPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRG--DY 395 PP +P P P A PP P + PPP G T+ PPP P PPP G Sbjct: 573 PPSVPSRAPVPPA-PPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPP---PPPLPGGVCIS 628 Query: 396 GPPGREMDTARTP 408 PP TA +P Sbjct: 629 SPPSLPGGTAISP 641 >gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo sapiens] Length = 309 Score = 119 bits (297), Expect = 9e-27 Identities = 93/233 (39%), Positives = 99/233 (42%), Gaps = 43/233 (18%) Query: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPG---GPPPP--FPAGQTPPR---- 238 PP G PQGG + + P PG P P G GPPP P GQ P Sbjct: 52 PPPGKPEGRPPQGGN-QSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQS 110 Query: 239 --PPLGPPGPPGPP--------GPPP-PGQVL-PPPLAGPPNRGDRPPPPVLFPGQPFGQ 286 PP P P GPP GPPP PG+ PPP G N+ PPP PG+P G Sbjct: 111 QGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGG--NQSQGPPPR---PGKPEGP 165 Query: 287 PPLGPLPPGPPPPVPG--YGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLP 344 PP G PPP PG GPPP QGPPP PG P P P G + PPP P Sbjct: 166 PPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPG--KPEGPPPQGGNQSQGPPPR-P 222 Query: 345 GPPPGAPP--------PAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389 G P G P P PH PPP P R PPP P G PPP Sbjct: 223 GKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKP---QRPPPPGRPQGPPPP 272 Score = 118 bits (295), Expect = 2e-26 Identities = 96/239 (40%), Positives = 106/239 (44%), Gaps = 51/239 (21%) Query: 187 GPP---GGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP--PPFPAGQTPPRPPL 241 GPP G S+ P+ G+ G+ P GG++ GP G P PP G PP Sbjct: 80 GPPPQGGNQSQGPPPRPGKPEGQPP---QGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPP 136 Query: 242 GPPGPPGPP--------GPPP-PGQVL-PPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGP 291 P P GPP GPPP PG+ PPP G N+ PPP PG+P G PP G Sbjct: 137 RPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGG--NQSQGPPP---HPGKPEGPPPQGG 191 Query: 292 LPPGPPPPVPG--YGPPP-------GPP--------PPQQGPPPPPGPFPPRPPGPLGPP 334 PPP PG GPPP GPP PP QG P GP PP P P GPP Sbjct: 192 NQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGP-PPHPGKPQGPP 250 Query: 335 LTLAPPPHLPGPPPGAP--PPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP--PP 389 P P PPPG P PP P NP PP P +GPPP GRP PP Sbjct: 251 PQEGNKPQRP-PPPGRPQGPPPPGGNPQQPLPP-----PAGKPQGPPPPPQGGRPHRPP 303 Score = 115 bits (287), Expect = 1e-25 Identities = 82/219 (37%), Positives = 93/219 (42%), Gaps = 27/219 (12%) Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPL 241 G+ + PP G +++ P G+ P G P PG P P P G + P Sbjct: 97 GKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGP- 155 Query: 242 GPPGPPGPPGPPPPG---QVLPPPLAG-----PPNRGDRPPPPVLFPGQPFGQPPLG--- 290 PP P P GPPP G PPP G PP G++ P PG+P G PP G Sbjct: 156 -PPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQ 214 Query: 291 ----PLPPGPP--PPVPGYGPPPGPPP---PQQGPPPPPGPFPPRPPGPLGPPLTLAPPP 341 P PG P PP G P GPPP QGPPP G P RPP P P PPP Sbjct: 215 SQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQ---GPPP 271 Query: 342 HLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPP 380 PG P P P P P PPP G P +G PP Sbjct: 272 --PGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPP 308 Score = 113 bits (283), Expect = 4e-25 Identities = 87/235 (37%), Positives = 98/235 (41%), Gaps = 48/235 (20%) Query: 212 PGGDRFPGPAGPGGPPPPFPAGQTPPRPPLG-------PPGPPGPPGPPPPG---QVLPP 261 P G R G P PPP G+ RPP G PP P P GPPP G PP Sbjct: 36 PEGRRPQGGNQPQRTPPP--PGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPP 93 Query: 262 PLAG-----PPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPG--YGPPPGPPPPQQ 314 P G PP G++ P PG+P G PP G PPP PG GPPP Q Sbjct: 94 PRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQ 153 Query: 315 GPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPP--------PAPHVNPAFFPPPT 366 GPPP PG P P P G + PPPH PG P G PP P P PPP Sbjct: 154 GPPPRPG--KPEGPPPQGGNQSQGPPPH-PGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQ 210 Query: 367 NSGMPTSDSRGPPP-------------TDPYGRPPPYDRGDYGPPGREMDTARTP 408 + S+GPPP P G PPP+ GPP +E + + P Sbjct: 211 GG----NQSQGPPPRPGKPEGPPSQGGNKPQG-PPPHPGKPQGPPPQEGNKPQRP 260 Score = 109 bits (273), Expect = 6e-24 Identities = 85/233 (36%), Positives = 98/233 (42%), Gaps = 25/233 (10%) Query: 183 EGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG-PGGPPPPFPAGQTPPRPPL 241 EG+ G + P G+ GR P GG++ GP PG P P P G + P Sbjct: 37 EGRRPQGGNQPQRTPPPPGKPEGRPP---QGGNQSQGPPPRPGKPEGPPPQGGNQSQGP- 92 Query: 242 GPPGPPGPPGPPPPG---QVLPPPLAG-----PPNRGDRPPPPVLFPGQPFGQPPLGPLP 293 PP P P G PP G PPP G PP G++ P PG+P G PP G Sbjct: 93 -PPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQ 151 Query: 294 PGPPPPVPGY--GPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAP 351 PPP PG GPPP QGPPP PG P P P G + PPP PG P G P Sbjct: 152 SQGPPPRPGKPEGPPPQGGNQSQGPPPHPGK--PEGPPPQGGNQSQGPPPR-PGKPEGPP 208 Query: 352 PPAPHVNPAFFPPPTNSGMPTSDS----RGPPPTD--PYGRPPPYDRGDYGPP 398 P + + P P P S +GPPP P G PP PP Sbjct: 209 PQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPP 261 Score = 105 bits (261), Expect = 1e-22 Identities = 77/200 (38%), Positives = 85/200 (42%), Gaps = 34/200 (17%) Query: 228 PPFPAGQTPPRPPLG-------PPGPPGPPGPPPPG---QVLPPPLAG-----PPNRGDR 272 P +G+ R P G PP P P G PP G PPP G PP G++ Sbjct: 29 PSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQ 88 Query: 273 PPPPVLFPGQPFGQPPLGPLPPGPPPPVPG--YGPPPGPPPPQQGPPPPPGPFPPRPPGP 330 P PG+P GQPP G PPP PG GPPP QGPPP PG P P P Sbjct: 89 SQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPG--KPEGPPP 146 Query: 331 LGPPLTLAPPPHLPGPPPGAPP--------PAPHVNPAFFPPPTNSGMPTSDSRGPPPT- 381 G + PPP PG P G PP P PH PPP + S+GPPP Sbjct: 147 QGGNQSQGPPPR-PGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGG----NQSQGPPPRP 201 Query: 382 -DPYGRPPPYDRGDYGPPGR 400 P G PP GPP R Sbjct: 202 GKPEGPPPQGGNQSQGPPPR 221 >gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 preproprotein [Homo sapiens] Length = 198 Score = 112 bits (279), Expect = 1e-24 Identities = 80/195 (41%), Positives = 86/195 (44%), Gaps = 39/195 (20%) Query: 208 PGAVPGGDRFPGPAG---PGGPPPPFPAGQTPPRPPLGPPGPPG--PPGPPPPGQVLPPP 262 P + G + P P G P GPPPP P P GPP G P GPPPPG+ PP Sbjct: 29 PSLIAGNPQGPSPQGGNKPQGPPPP-------PGKPQGPPPQGGNKPQGPPPPGKPQGPP 81 Query: 263 LAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPP--QQGPPPPP 320 G +R R PP G+P G PP G P GPPP G P GPPPP QGPP Sbjct: 82 PQGDKSRSPRSPP-----GKPQGPPPQGGKPQGPPP--QGGNKPQGPPPPGKPQGPPAQG 134 Query: 321 G---PFPPRPPG-PLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSR 376 G PPG P GPP P P PP G P P PA G P + Sbjct: 135 GSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPA--------GQP----Q 182 Query: 377 GPPPTDPYGRP--PP 389 GPP GRP PP Sbjct: 183 GPPRPPQGGRPSRPP 197 Score = 89.0 bits (219), Expect = 1e-17 Identities = 64/153 (41%), Positives = 72/153 (47%), Gaps = 16/153 (10%) Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPP-PFPAGQTPPRPP 240 G+ + PP G ++ PQG G+ G P GD+ P P G P P P G P PP Sbjct: 55 GKPQGPPPQGGNK---PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPP 111 Query: 241 LGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPL-GPLPPGPPPP 299 P G P GPPPPG+ PP G PP G+P G P G P GPPPP Sbjct: 112 --PQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPP----GKPQGPPQQEGNNPQGPPPP 165 Query: 300 VPGYGP--PPGPPPPQ-QGPP-PPPGPFPPRPP 328 G P P PP Q QGPP PP G P RPP Sbjct: 166 A-GGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 197 Score = 80.5 bits (197), Expect = 4e-15 Identities = 58/154 (37%), Positives = 63/154 (40%), Gaps = 30/154 (19%) Query: 249 PPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGP-LPPGPPPPVPGYGPPP 307 P GP P G N+ PPPP PG+P G PP G P GPPPP G P Sbjct: 36 PQGPSPQGG----------NKPQGPPPP---PGKPQGPPPQGGNKPQGPPPP----GKPQ 78 Query: 308 GPPPP---QQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPP 364 GPPP + P PPG P PP G P PPP P G PPP P Sbjct: 79 GPPPQGDKSRSPRSPPGK-PQGPPPQGGKPQ--GPPPQGGNKPQGPPPPGKPQGP----- 130 Query: 365 PTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPP 398 P G + +R PP P G P GPP Sbjct: 131 PAQGGSKSQSARSPPGK-PQGPPQQEGNNPQGPP 163 Score = 57.0 bits (136), Expect = 4e-08 Identities = 48/122 (39%), Positives = 54/122 (44%), Gaps = 28/122 (22%) Query: 304 GPPPGPPPP----QQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPP------ 353 G P GP P QGPPPPPG P+ P P G PPP PG P PPP Sbjct: 34 GNPQGPSPQGGNKPQGPPPPPGK--PQGPPPQGGNKPQGPPP--PGKPQ-GPPPQGDKSR 88 Query: 354 APHVNPAF-FPPPTNSGMPTSDSRGPPP---TDPYGRPPPYDRGDYGPP---GREMDTAR 406 +P P PP G P +GPPP P G PPP GPP G + +AR Sbjct: 89 SPRSPPGKPQGPPPQGGKP----QGPPPQGGNKPQGPPPP--GKPQGPPAQGGSKSQSAR 142 Query: 407 TP 408 +P Sbjct: 143 SP 144 Score = 42.7 bits (99), Expect = 9e-04 Identities = 38/115 (33%), Positives = 45/115 (39%), Gaps = 30/115 (26%) Query: 170 QSRKTTQSGQMSGEGKAGPP-GGSSRAAFPQGG-RGRGRFPGAVPGGDRFPG-------- 219 Q K+ G+ + PP GG + PQGG + +G P P G G Sbjct: 83 QGDKSRSPRSPPGKPQGPPPQGGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSAR 142 Query: 220 --PAGPGGPP---------PPFPAGQTPPRP-------PLGPPGPP--GPPGPPP 254 P P GPP PP PAG P +P P GPP PP G P PP Sbjct: 143 SPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 197 Score = 32.7 bits (73), Expect = 0.89 Identities = 26/78 (33%), Positives = 31/78 (39%), Gaps = 16/78 (20%) Query: 334 PLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPP---TDPYGRPPPY 390 P +A P P P G P P PPP G P +GPPP P G PPP Sbjct: 29 PSLIAGNPQGPSPQGGNKPQGP-------PPPP--GKP----QGPPPQGGNKPQGPPPPG 75 Query: 391 DRGDYGPPGREMDTARTP 408 P G + + R+P Sbjct: 76 KPQGPPPQGDKSRSPRSP 93 >gi|4826998 splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) [Homo sapiens] Length = 707 Score = 110 bits (274), Expect = 4e-24 Identities = 86/234 (36%), Positives = 98/234 (41%), Gaps = 34/234 (14%) Query: 185 KAGPPGGSSRAAFPQGGRGRG-----RFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRP 239 + G GG R GG GRG R P G ++ GP GPG GQ+ P+P Sbjct: 9 RGGGGGGFHRRG---GGGGRGGLHDFRSPPPGMGLNQNRGPMGPG-------PGQSGPKP 58 Query: 240 PLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPP 299 P+ PP P PPP Q PPP PP++ PPP P Q QPP P P P Sbjct: 59 PIPPPPPHQQQQQPPPQQ--PPPQQPPPHQ----PPPHPQPHQQ-QQPP--PPPQDSSKP 109 Query: 300 VPGYGPPPGP-----PPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPA 354 V GP P P PP PP P PPG GP T PPP + PPGAPPP Sbjct: 110 VVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGS-GPGPTPTPPPAVTSAPPGAPPPT 168 Query: 355 PHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTP 408 P + PP G P + P P G P G GP G +M P Sbjct: 169 PPSSGVPTTPPQAGGPPPPPAAVPGP----GPGPKQGPGPGGPKGGKMPGGPKP 218 Score = 105 bits (261), Expect = 1e-22 Identities = 86/258 (33%), Positives = 91/258 (35%), Gaps = 53/258 (20%) Query: 178 GQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPP 237 G G G GG P G G + G + G GP P PPPP Q PP Sbjct: 14 GGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPP 73 Query: 238 R---PPLGPPGPPGPPGPPPPGQVLPPP----------LAGP---PNRGDRPP------- 274 PP PP PP P P Q PPP GP P G PP Sbjct: 74 PQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPP 133 Query: 275 --------PPVLFPGQ-PFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPP----- 320 PP PG P P + PPG PPP P P PP GPPPPP Sbjct: 134 ATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPG 193 Query: 321 -GPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMP-------- 371 GP P + PGP GP P PG PG P H PP G P Sbjct: 194 PGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPK----PPHRGGGEPRGGRQHHP 249 Query: 372 ---TSDSRGPPPTDPYGR 386 +GPPP P GR Sbjct: 250 PYHQQHHQGPPPGGPGGR 267 >gi|116284398 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 108 bits (271), Expect = 1e-23 Identities = 92/265 (34%), Positives = 104/265 (39%), Gaps = 65/265 (24%) Query: 190 GGSSRAAFPQGGRGRGRFPGAVPGGD-RFPGPAGPG---GPPPPFPAGQTPPRPPLGPPG 245 GGS P GGR P + P G RFP P+ PG GPP P PPRP +G Sbjct: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPS-PGHRSGPPEPQRNRMPPPRPDVGSKP 180 Query: 246 ---PPGPPGPPPPGQVLP-----PPLAGPPNRGDRPPPPVLFPGQ--------------- 282 PP P P P Q P PP+ G P + P P FPG Sbjct: 181 DSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPL 240 Query: 283 ----PFG-QPPLGPLPPG-----PPPPVPGYGPPPG-------PPPPQQGPPPPPGPFPP 325 PF +PPL P P PPPP P G P PPPPQ PP P P Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP 300 Query: 326 RPPGPLGPPLTLAPPPHLPGPPPGAPP----------PAPHVNPAFFPPPTNSGMPTSDS 375 PP PPP PGPPP P P +++ + PP +P+ Sbjct: 301 SASSQAPPP---PPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPP----LPSPGR 353 Query: 376 RGPPPTDPYGRPPPYDRGDYGPPGR 400 GP P P RPPP R PPGR Sbjct: 354 SGPLPPPPSERPPPPVR---DPPGR 375 Score = 99.0 bits (245), Expect = 1e-20 Identities = 93/303 (30%), Positives = 110/303 (36%), Gaps = 66/303 (21%) Query: 144 LPKRELHGQNPVVTPCNK-QFLSQFEMQSRKTTQSGQMSGEGKAGPPGG-SSRAAFPQGG 201 L K E G+N +++ +K + L + R + G G G GG F GG Sbjct: 25 LNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDKPKGAGAGGGGGGFGGGGGFGGGG 84 Query: 202 RGRGRFPGAVPGGDRFPGPAG------------------PGGPPPPF--PAGQTPPRPPL 241 G G G GG PG G GG PP P G++ P Sbjct: 85 GGGG---GGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPF 141 Query: 242 GPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGP----- 296 PP PG P PG PP P R PPP +P PP P P P Sbjct: 142 SPPSGPGRFPVPSPGHRSGPP---EPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSP 198 Query: 297 ----PPPVPG--YGPPPGPPPP---------------QQGPPPPPGPFPPRPPGPLGPPL 335 PPVPG P PGP PP +Q P PF RPP P P Sbjct: 199 HNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSR 258 Query: 336 TLAPPPHLPGPPPG---------APPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGR 386 L P P PP G PPP P N PP ++ P++ S+ PPP P R Sbjct: 259 ALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNK---PPVPSTPRPSASSQAPPPPPPPSR 315 Query: 387 PPP 389 P P Sbjct: 316 PGP 318 Score = 78.2 bits (191), Expect = 2e-14 Identities = 72/213 (33%), Positives = 80/213 (37%), Gaps = 55/213 (25%) Query: 204 RGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQV----- 258 R P P ++ P P+ P P + Q PP PP PP PGPP PP Sbjct: 279 REAVPPPPPQNNKPPVPS----TPRPSASSQAPPPPP--PPSRPGPPPLPPSSSGNDETP 332 Query: 259 -LP----------PPLAGPPNRGDRPPPPVLFPGQPFGQPP--LGPLPPGPPPPVPGYGP 305 LP PPL P G PPPP P P PP GPLP PPPPV G Sbjct: 333 RLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLP--PPPPVSRNGS 390 Query: 306 -----PPGPPPPQQG--PPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVN 358 P P P + P GP PP PP P APPP PPP+ + Sbjct: 391 TSRALPATPQLPSRSGVDSPRSGPRPPLPP---DRPSAGAPPP---------PPPSTSIR 438 Query: 359 PAFFPPPTNSGM-------PTSDSRGPPPTDPY 384 F P P SD PP +PY Sbjct: 439 NGFQDSPCEDEWESRFYFHPISDL---PPPEPY 468 >gi|38373695 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 108 bits (271), Expect = 1e-23 Identities = 92/265 (34%), Positives = 104/265 (39%), Gaps = 65/265 (24%) Query: 190 GGSSRAAFPQGGRGRGRFPGAVPGGD-RFPGPAGPG---GPPPPFPAGQTPPRPPLGPPG 245 GGS P GGR P + P G RFP P+ PG GPP P PPRP +G Sbjct: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPS-PGHRSGPPEPQRNRMPPPRPDVGSKP 180 Query: 246 ---PPGPPGPPPPGQVLP-----PPLAGPPNRGDRPPPPVLFPGQ--------------- 282 PP P P P Q P PP+ G P + P P FPG Sbjct: 181 DSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPL 240 Query: 283 ----PFG-QPPLGPLPPG-----PPPPVPGYGPPPG-------PPPPQQGPPPPPGPFPP 325 PF +PPL P P PPPP P G P PPPPQ PP P P Sbjct: 241 SSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP 300 Query: 326 RPPGPLGPPLTLAPPPHLPGPPPGAPP----------PAPHVNPAFFPPPTNSGMPTSDS 375 PP PPP PGPPP P P +++ + PP +P+ Sbjct: 301 SASSQAPPP---PPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPP----LPSPGR 353 Query: 376 RGPPPTDPYGRPPPYDRGDYGPPGR 400 GP P P RPPP R PPGR Sbjct: 354 SGPLPPPPSERPPPPVR---DPPGR 375 Score = 99.0 bits (245), Expect = 1e-20 Identities = 93/303 (30%), Positives = 110/303 (36%), Gaps = 66/303 (21%) Query: 144 LPKRELHGQNPVVTPCNK-QFLSQFEMQSRKTTQSGQMSGEGKAGPPGG-SSRAAFPQGG 201 L K E G+N +++ +K + L + R + G G G GG F GG Sbjct: 25 LNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDKPKGAGAGGGGGGFGGGGGFGGGG 84 Query: 202 RGRGRFPGAVPGGDRFPGPAG------------------PGGPPPPF--PAGQTPPRPPL 241 G G G GG PG G GG PP P G++ P Sbjct: 85 GGGG---GGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPF 141 Query: 242 GPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGP----- 296 PP PG P PG PP P R PPP +P PP P P P Sbjct: 142 SPPSGPGRFPVPSPGHRSGPP---EPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSP 198 Query: 297 ----PPPVPG--YGPPPGPPPP---------------QQGPPPPPGPFPPRPPGPLGPPL 335 PPVPG P PGP PP +Q P PF RPP P P Sbjct: 199 HNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSR 258 Query: 336 TLAPPPHLPGPPPG---------APPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGR 386 L P P PP G PPP P N PP ++ P++ S+ PPP P R Sbjct: 259 ALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNK---PPVPSTPRPSASSQAPPPPPPPSR 315 Query: 387 PPP 389 P P Sbjct: 316 PGP 318 Score = 78.2 bits (191), Expect = 2e-14 Identities = 72/213 (33%), Positives = 80/213 (37%), Gaps = 55/213 (25%) Query: 204 RGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQV----- 258 R P P ++ P P+ P P + Q PP PP PP PGPP PP Sbjct: 279 REAVPPPPPQNNKPPVPS----TPRPSASSQAPPPPP--PPSRPGPPPLPPSSSGNDETP 332 Query: 259 -LP----------PPLAGPPNRGDRPPPPVLFPGQPFGQPP--LGPLPPGPPPPVPGYGP 305 LP PPL P G PPPP P P PP GPLP PPPPV G Sbjct: 333 RLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLP--PPPPVSRNGS 390 Query: 306 -----PPGPPPPQQG--PPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVN 358 P P P + P GP PP PP P APPP PPP+ + Sbjct: 391 TSRALPATPQLPSRSGVDSPRSGPRPPLPP---DRPSAGAPPP---------PPPSTSIR 438 Query: 359 PAFFPPPTNSGM-------PTSDSRGPPPTDPY 384 F P P SD PP +PY Sbjct: 439 NGFQDSPCEDEWESRFYFHPISDL---PPPEPY 468 >gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] Length = 464 Score = 108 bits (271), Expect = 1e-23 Identities = 95/264 (35%), Positives = 103/264 (39%), Gaps = 55/264 (20%) Query: 161 KQFLSQFEMQSRKTTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGP 220 KQF QF + K PP S A P G + R P + G P P Sbjct: 204 KQFFLQFHFKMEK--------------PPAPPSLPAGPPGVK---RPPPPLMNGLP-PRP 245 Query: 221 AGPGGPPPPFPAG-QTPPRPPLGPPGPPGPPGPP----------PPGQVLPPPLAG--PP 267 P PPP P G PP PP GP P GPPGPP PP V+ PP +G PP Sbjct: 246 PLPESLPPPPPGGLPLPPMPPTGP-APSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPP 304 Query: 268 NRGDRPPPPVLFPGQPFGQPPLG---PLPPGPPPPVPGYGPP-PGPPPPQQGP-PPPPGP 322 G PP P + P P PP P PG PP PG PP PG PP G PP PG Sbjct: 305 APGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGV 364 Query: 323 FPPRPPG--PLGPPLTLAPP---PHLPGPPPGAP------------PPAPHVN-PAFFPP 364 PP G P P + A P P PG P AP PP H + P P Sbjct: 365 HPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQ 424 Query: 365 PTNSGMPTSDSRGPPPTDPYGRPP 388 P P P P RPP Sbjct: 425 PPGVHPSNPGVHPPTPMPPMLRPP 448 Score = 81.3 bits (199), Expect = 2e-15 Identities = 55/135 (40%), Positives = 60/135 (44%), Gaps = 31/135 (22%) Query: 271 DRPPPPVLFPGQPFGQPPLGPLPPG---PPPPVPGYGPPPGPPPPQQGPPPPPG-----P 322 ++PP P P P G PPG PPPP+ G PP PP P+ PPPPPG P Sbjct: 215 EKPPAP---PSLPAG-------PPGVKRPPPPLMN-GLPPRPPLPESLPPPPPGGLPLPP 263 Query: 323 FPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNP---AFFPPPTNSGMPTSDSRGP- 378 PP P P GPP PP LP P PG PPAP V+P PP P P Sbjct: 264 MPPTGPAPSGPP----GPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPA 319 Query: 379 ----PPTDPYGRPPP 389 PPT P P Sbjct: 320 PGVHPPTSGVHPPAP 334 Score = 80.9 bits (198), Expect = 3e-15 Identities = 65/164 (39%), Positives = 70/164 (42%), Gaps = 30/164 (18%) Query: 208 PGAVPGGDRFPGPAGPGGPP-----PPFPAGQTPPRPPLGPPGP---PGPPG--PPPPGQ 257 PG P PA PP PP P G PP P + PP P P PG PP PG Sbjct: 306 PGVHPPAPGVHPPAPGVHPPTSGVHPPAP-GVHPPAPGVHPPAPGVHPPAPGVHPPAPG- 363 Query: 258 VLPPPLAG--PPNRGDRPPPPVLFPGQPFGQPP----------LGPLPPGPPPPVPGYGP 305 V PPP AG P G P P + P P PP + P PPG P PG P Sbjct: 364 VHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHP 423 Query: 306 -PPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPP 348 PPG P G PP P PP L PPL P ++P PPP Sbjct: 424 QPPGVHPSNPGVHPPT-PMPPM----LRPPLPSEGPGNIPPPPP 462 Score = 77.0 bits (188), Expect = 4e-14 Identities = 64/171 (37%), Positives = 71/171 (41%), Gaps = 37/171 (21%) Query: 246 PPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGP 305 PP PP P AGPP RPPPP++ G PP PLP PPP PG P Sbjct: 217 PPAPPSLP----------AGPPGV-KRPPPPLMN-----GLPPRPPLPESLPPPPPGGLP 260 Query: 306 PPGPPPPQQGPPPPPGP-----FPPRPPGPLGPPLTLAPPPHLPGPP-PGAPPPAPHVNP 359 P PP P P GP PP PG P + PP PP PG PPAP V+P Sbjct: 261 LPPMPPTG---PAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHP 317 Query: 360 AF--FPPPTNSGMPTSDSRGPP-----PTDPYGRPP-----PYDRGDYGPP 398 PPT+ P + PP P P PP P G + PP Sbjct: 318 PAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPP 368 Score = 41.6 bits (96), Expect = 0.002 Identities = 29/77 (37%), Positives = 30/77 (38%), Gaps = 18/77 (23%) Query: 324 PPRPPG-PLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTD 382 PP PP P GPP PPP L P PP P PPP G+P PPT Sbjct: 217 PPAPPSLPAGPPGVKRPPPPLMNGLPPRPPL-----PESLPPPPPGGLPLPPM---PPTG 268 Query: 383 PYGRPPPYDRGDYGPPG 399 P GPPG Sbjct: 269 P---------APSGPPG 276 >gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo sapiens] Length = 247 Score = 108 bits (270), Expect = 1e-23 Identities = 86/228 (37%), Positives = 93/228 (40%), Gaps = 36/228 (15%) Query: 191 GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPG---GPPPPFPAGQTPPRPPLG----- 242 G PQGG R P PG + P P G GPPPP G+ RPP G Sbjct: 34 GKPEGRRPQGGNQPQR-PPPPPGKPQGPPPQGGNQSQGPPPP--PGKPEGRPPQGGNQSQ 90 Query: 243 -PPGPPGPPGPPPP-----GQVLPPPLAGPP-------NRGDRPPPPVLFPGQPFGQPPL 289 PP PG P PPP Q PPP P N+ RPPPP PG+P PP Sbjct: 91 GPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPP---PGKPERPPPQ 147 Query: 290 GPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPG 349 G PPP PG P PPPQ+G PP P GPP P P PPPG Sbjct: 148 GGNQSQGPPPHPG---KPEGPPPQEGNKSRSARSPPGK--PQGPPQQEGNKPQGP-PPPG 201 Query: 350 APPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGP 397 P P PA P P +GPPP GRPP +G P Sbjct: 202 KPQGPP---PAGGNPQQPQAPPAGKPQGPPPPPQGGRPPRPAQGQQPP 246 Score = 99.8 bits (247), Expect = 6e-21 Identities = 74/185 (40%), Positives = 84/185 (45%), Gaps = 37/185 (20%) Query: 232 AGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGP 291 +G+ R P G P PP PPPG+ PP G N+ PPPP PG+P G+PP G Sbjct: 33 SGKPEGRRPQGGNQPQRPP--PPPGKPQGPPPQG-GNQSQGPPPP---PGKPEGRPPQGG 86 Query: 292 LPPGPPPPVP---------------GYGPPPGPP--PPQQG------PPPPPGPFPPRPP 328 PPP P G PPPG P PP QG PPPPPG P RPP Sbjct: 87 NQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGK-PERPP 145 Query: 329 GPLGPPLTLAPPPHLPGPPPGAPPPAPHVN-PAFFPPPTNSGMPTSDSR----GPPPTDP 383 P G + PPPH PG P G PP + + A PP G P + PPP P Sbjct: 146 -PQGGNQSQGPPPH-PGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKP 203 Query: 384 YGRPP 388 G PP Sbjct: 204 QGPPP 208 Score = 93.2 bits (230), Expect = 6e-19 Identities = 73/188 (38%), Positives = 80/188 (42%), Gaps = 36/188 (19%) Query: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG----PGGPPPPFPAGQTPP------ 237 PP G PQGG + + P PG P P G G PPPP + PP Sbjct: 73 PPPGKPEGRPPQGGN-QSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQS 131 Query: 238 -RPPLGPPGPPGPP--------GPPP-PGQVL-PPPLAGPPNRGDRPPPPVLFPGQPFGQ 286 RPP P P PP GPPP PG+ PPP G +R R P PG+P G Sbjct: 132 HRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSP-----PGKPQGP 186 Query: 287 PPL-GPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPG 345 P G P GPPPP GPPP PQQ PP G +P GP PP P P Sbjct: 187 PQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAPPAG----KPQGPPPPPQGGRP----PR 238 Query: 346 PPPGAPPP 353 P G PP Sbjct: 239 PAQGQQPP 246 Score = 89.0 bits (219), Expect = 1e-17 Identities = 71/188 (37%), Positives = 82/188 (43%), Gaps = 53/188 (28%) Query: 231 PAGQTPP--RPPLGPPGPPGPP-GPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQP 287 P G+ P P PP PPG P GPPP G N+ PPPP PG+P G+P Sbjct: 36 PEGRRPQGGNQPQRPPPPPGKPQGPPPQGG----------NQSQGPPPP---PGKPEGRP 82 Query: 288 PLGPLPPGPPPPVPGYGPPPGPPPPQ-----QGPPPPPGPFPPRPPGPLGPPLTLAPPPH 342 P G PPP PG P PPPQ QG PPPPG P RPP P G H Sbjct: 83 PQGGNQSQGPPPHPG---KPERPPPQGGNQSQGTPPPPGK-PERPP-PQG-----GNQSH 132 Query: 343 LPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREM 402 P PPPG P PPP + S+GPPP + GPP +E Sbjct: 133 RPPPPPGKPER---------PPPQGG----NQSQGPPP---------HPGKPEGPPPQEG 170 Query: 403 DTARTPLS 410 + +R+ S Sbjct: 171 NKSRSARS 178 Score = 80.1 bits (196), Expect = 5e-15 Identities = 52/129 (40%), Positives = 57/129 (44%), Gaps = 11/129 (8%) Query: 278 LFPGQPFGQPPLGPLPPGPPPPVPG--YGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPL 335 L G+P G+ P G P PPP PG GPPP QGPPPPPG RP P G Sbjct: 31 LISGKPEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRP--PQGGNQ 88 Query: 336 TLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMP-----TSDSRGPPPTDPYGRPPPY 390 + PPPH PG P PP + + PPP P R PPP RPPP Sbjct: 89 SQGPPPH-PGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQ 147 Query: 391 -DRGDYGPP 398 GPP Sbjct: 148 GGNQSQGPP 156 Score = 52.0 bits (123), Expect = 1e-06 Identities = 51/156 (32%), Positives = 56/156 (35%), Gaps = 42/156 (26%) Query: 172 RKTTQSGQMSGEGKAGPPGGSSRAAFPQGG---RGRGRFPGAVPG-----GDRFPGPAGP 223 R Q G S + PP G PQGG +G PG G G++ P Sbjct: 122 RPPPQGGNQSH--RPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSP 179 Query: 224 GGPP--PPFPAGQTPPRPPLGPPG-PPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFP 280 G P PP G P PP PPG P G PPP G P + PP Sbjct: 180 PGKPQGPPQQEGNKPQGPP--PPGKPQG-----------PPPAGGNPQQPQAPP------ 220 Query: 281 GQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGP 316 P GPPPP G G PP P QQ P Sbjct: 221 ---------AGKPQGPPPPPQG-GRPPRPAQGQQPP 246 Score = 32.3 bits (72), Expect = 1.2 Identities = 22/61 (36%), Positives = 25/61 (40%), Gaps = 2/61 (3%) Query: 179 QMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGD-RFPGPAGPGGPPPPFPAGQTPP 237 Q G GPP P G G + P A P G + P P GG PP GQ PP Sbjct: 188 QQEGNKPQGPPPPGKPQGPPPAG-GNPQQPQAPPAGKPQGPPPPPQGGRPPRPAQGQQPP 246 Query: 238 R 238 + Sbjct: 247 Q 247 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 107 bits (266), Expect = 4e-23 Identities = 104/287 (36%), Positives = 117/287 (40%), Gaps = 72/287 (25%) Query: 178 GQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP---PPFPAGQ 234 GQ G GP G F +G RG P PG PG GP GPP PP P G+ Sbjct: 579 GQDGLPGLPGPKGEPGGITF-KGERG----PPGNPGLPGLPGNIGPMGPPGFGPPGPVGE 633 Query: 235 TPPRPPLGPPGPPGPPGPP-PPGQVLPPP----LAGPPNR-GDRPPPPVLFPGQPF--GQ 286 + G PG PG PGP PGQ + P L G P R GD V PG P GQ Sbjct: 634 KGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGD-----VGLPGDPGLPGQ 688 Query: 287 PPLGPLP-------------PGPPPP--VPGYGPPPGPPPPQ-----QGPPPPPG----- 321 P L +P PGPP P PG PPG P +GPP PPG Sbjct: 689 PGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPK 748 Query: 322 -------PFPPRPPGPLGPPLTLAPP-----PHLPGPP-----PGAPPPAPHVNPAFFPP 364 P PP PPG G L P P PGPP G P P V P P Sbjct: 749 GEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPG 808 Query: 365 PTN-SGMPTSDSRGPPP----TDPYGRPP----PYDRGDYGPPGREM 402 P G+P +GPP P G+P P ++GD GPPG ++ Sbjct: 809 PMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV 855 Score = 100 bits (249), Expect = 3e-21 Identities = 94/271 (34%), Positives = 109/271 (40%), Gaps = 63/271 (23%) Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG-------------PGGPPP 228 G G GPPG + G +G G PG +PG PGP G PG P Sbjct: 1188 GFGNPGPPGLPGLS----GQKGDGGLPG-IPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS 1242 Query: 229 PFPAGQTPPRPPLGPPGPPGPPGPPP----PGQVLPPPLAG------------------- 265 P PA + P P GP GPPG PGP PG PP L G Sbjct: 1243 PGPALEGPKGNP-GPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGL 1301 Query: 266 PPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPP-PPVPGYGPPPGPP--PPQQGPPPPPG- 321 P +GD+ PP + G P G+P L + P P VPG+ GP P GP PG Sbjct: 1302 PGLKGDQGPPGL--QGNP-GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGL 1358 Query: 322 ---PFPPRPPGPLGPPLTL---APPPHLPGPPPGAPPPAPHVNPAFFPPPT-------NS 368 P PP PGP G + + A PP +PG P P P P P PT + Sbjct: 1359 IGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQ-GPQGLPGPTGPPGDPGRN 1417 Query: 369 GMPTSDSRGPPPTDPYGRPPPYDRGDYGPPG 399 G+P D G DP P RG GPPG Sbjct: 1418 GLPGFDGAGGRKGDPGLPGQPGTRGLDGPPG 1448 Score = 99.0 bits (245), Expect = 1e-20 Identities = 92/252 (36%), Positives = 102/252 (40%), Gaps = 53/252 (21%) Query: 189 PGGSSRAAFPQGGRGRGRFPGAV--PGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGP 246 PG + +G +G FPG PG FPGP GP GP GQ GPPGP Sbjct: 34 PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGP-----RGQKGDDGIPGPPGP 88 Query: 247 PGPPGPPP-PGQVLPPPLAGPPNRGDRPPPPVL-----------FPGQPFGQPPLGPLPP 294 G GPP PG P L G P P P + FPG P G P L PP Sbjct: 89 KGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSP-GFPGLQG-PP 146 Query: 295 GPPPPVPGYGPPPGP------PPPQQGP--PPPPG----PFPPRPPGPLGPPLTLAPPPH 342 G PP +PG PG P P+ P P PPG P P PGP+GPP PP Sbjct: 147 G-PPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPP----GPPG 201 Query: 343 LPGP--PPGAPPPAPHVNPAFFPPPTNSG-MPTSDSRGPPPTDPYGRPP----------- 388 L GP PPG P P ++ F P G GPP + P Sbjct: 202 LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261 Query: 389 -PYDRGDYGPPG 399 P DRG GPPG Sbjct: 262 LPGDRGPPGPPG 273 Score = 97.8 bits (242), Expect = 2e-20 Identities = 90/240 (37%), Positives = 101/240 (42%), Gaps = 38/240 (15%) Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAV-----PGGDRFPGPAGPGG---PPPPFPAG 233 G G GPPG P G G PG + PG FPGP G G P PP P G Sbjct: 705 GIGLPGPPGPKGFPGIP-GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPG 763 Query: 234 QTPPRPPLGPPGP---PGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLG 290 + LGP G PGPPG PPG+ L GP +GD P P P G P +G Sbjct: 764 LPGFKGALGPKGDRGFPGPPG--PPGRTGLDGLPGP--KGDVGPNGQPGPMGPPGLPGIG 819 Query: 291 PLPPGPPPPVPGYGPPPGPP-----PPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPG 345 P PP +PG P G P P ++G P PPG P PPG G P P PG Sbjct: 820 VQGPPGPPGIPG---PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSP----GIPGAPG 872 Query: 346 P--PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMD 403 P PPG+P + F P T M GPP P G P G G PG + D Sbjct: 873 PIGPPGSPGLPGKAGASGF-PGTKGEMGMMGPPGPP--GPLGIP-----GRSGVPGLKGD 924 Score = 91.3 bits (225), Expect = 2e-18 Identities = 93/271 (34%), Positives = 105/271 (38%), Gaps = 56/271 (20%) Query: 174 TTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG----PGGPPPP 229 T + G G GPPG G +G PG +PG GP G PG P P Sbjct: 937 TGEKGSKGEPGLPGPPGPMDPNLL--GSKGEKGEPG-LPGIPGVSGPKGYQGLPGDPGQP 993 Query: 230 FPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGP--------PNRGDRPPPPVLFPG 281 +GQ P GP G PG PG PG + PP L G P + PP P PG Sbjct: 994 GLSGQPGLPGPPGPKGNPGLPG--QPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPG 1051 Query: 282 QPFGQPPLG----------------PLPPGP--PPPVPGY----------GPP--PGPP- 310 QP G P L P PGP P +PGY G P PG P Sbjct: 1052 QP-GSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPG 1110 Query: 311 -PPQQGPPPPPG-PFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNS 368 P +G P PG P P PPGP G ++ PP PG P P +P PP Sbjct: 1111 TPGAKGQPGLPGFPGTPGPPGPKG----ISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEK 1166 Query: 369 GMPTSDSRGPPPTDPYGRPPPYDRGDYGPPG 399 G P D P P G P G+ GPPG Sbjct: 1167 GKPGQDGI-PGPAGQKGEPGQPGFGNPGPPG 1196 Score = 90.1 bits (222), Expect = 5e-18 Identities = 103/295 (34%), Positives = 106/295 (35%), Gaps = 78/295 (26%) Query: 176 QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAV--PG-----GDR-FPGPAGPGGPP 227 Q G G GPPG P+G G PG + PG GD FPGP G GPP Sbjct: 992 QPGLSGQPGLPGPPG-------PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPP 1044 Query: 228 PPFPAGQTPPRP------------------------PLGPPGPPGPPGPPP-PGQVLPPP 262 P P P P G PG PG PG P G V P Sbjct: 1045 GPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPG 1104 Query: 263 LAGPPNRGDRPPPPVL--FPGQP-------FGQPPLGPLPPGPPPPVPGYGPP--PGPP- 310 L G P P L FPG P PP P PG P PV G G P PGPP Sbjct: 1105 LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164 Query: 311 ----PPQQGPPPPPGP--FPPRP----PGPLGPPLTLAPPPH--LPGPPPGAPPPAPHVN 358 P Q G P P G P +P PGP G P LPG P P P Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGE 1224 Query: 359 PAF--FP----PPTNSGMPTSDSRGPP----PTDPYGRPPPYD----RGDYGPPG 399 P F FP PP G P GP P P GRP P G GPPG Sbjct: 1225 PGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPG 1279 Score = 84.7 bits (208), Expect = 2e-16 Identities = 88/246 (35%), Positives = 96/246 (39%), Gaps = 50/246 (20%) Query: 176 QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDR--FPGPAGPGGPPP----P 229 Q G G GPPG + P G G PG V GG PGP G G P P Sbjct: 1117 QPGLPGFPGTPGPPGPKGISG-PPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIP 1175 Query: 230 FPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRP--PPPVLFPGQPFGQP 287 PAGQ G PG PG P PPG P L+G G P P PG P G+P Sbjct: 1176 GPAGQK------GEPGQPGFGNPGPPGL---PGLSGQKGDGGLPGIPGNPGLPG-PKGEP 1225 Query: 288 PLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGP-FPPRPPGPLGPPLTLAPPPHLPGP 346 P PP GPP P P +GP PGP PP PGP G LPGP Sbjct: 1226 GFHGFPGVQGPP----GPPGSPGPALEGPKGNPGPQGPPGRPGPTG-------FQGLPGP 1274 Query: 347 --PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDT 404 PPG P N N G P G P P +GD GPPG + + Sbjct: 1275 EGPPGLPG-----NGGIKGEKGNPGQP-----GLPGL-------PGLKGDQGPPGLQGNP 1317 Query: 405 ARTPLS 410 R L+ Sbjct: 1318 GRPGLN 1323 Score = 80.9 bits (198), Expect = 3e-15 Identities = 87/255 (34%), Positives = 99/255 (38%), Gaps = 43/255 (16%) Query: 178 GQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPG-----AVPGGDRFPGPAG-------PGG 225 G+M G GPPG P G GR PG + G PGP G PG Sbjct: 896 GEMGMMGPPGPPG-------PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGL 948 Query: 226 PPPPFPA-----GQTPPRPPLGPPGPPGPPGPPP----PGQVLPPPLAGPPNRGDRPPPP 276 P PP P G + G PG PG GP PG P L+G P PP P Sbjct: 949 PGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL-PGPPGP 1007 Query: 277 VLFPGQPFGQPPLGPLPPGPPPPVPGYGPP-----PGPPPPQQGPPPPPGPFPPRPPGPL 331 PG P GQP L PPG + G P GPP P P P P P G Sbjct: 1008 KGNPGLP-GQPGLIG-PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065 Query: 332 GPP-LTLAPPPHLPGP--PPGAP--PPAPHVNPAFFPP--PTNSGMPTSDSRGPPPTDPY 384 G P ++ P LPGP PG P P P + + P P G P + + P P Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG 1125 Query: 385 GRPPPYDRGDYGPPG 399 PP +G GPPG Sbjct: 1126 TPGPPGPKGISGPPG 1140 Score = 79.3 bits (194), Expect = 8e-15 Identities = 97/320 (30%), Positives = 110/320 (34%), Gaps = 111/320 (34%) Query: 184 GKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG-PGGPPPPFPAGQTPPRP--- 239 G GPPG P G G PG++ PGP G PG P PP G P Sbjct: 141 GLQGPPG-------PPGIPGMKGEPGSIIMSS-LPGPKGNPGYPGPPGIQGLPGPTGIPG 192 Query: 240 PLGPPGPPG---PPGPP---------------PPGQVLPPPLAGPPN-----RGDRPPPP 276 P+GPPGPPG PPGPP P G+ L GPP + P Sbjct: 193 PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252 Query: 277 VLF----PGQPFGQPPLGPL----PPGPP---------------------------PPVP 301 V F G P + P GP PPGPP P +P Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312 Query: 302 GYGPPPGPP-----------PPQQGPPPPPGPFPPRP--------PGPLGPP-------- 334 G PG P GPP PPG PRP G +G P Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372 Query: 335 ---LTLAPPPHLPGPPPGA--PPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP-- 387 + PP LPGPP A PP P P + G P GPP D G+P Sbjct: 373 RGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLD--GQPGA 430 Query: 388 -----PPYDRGDYGPPGREM 402 PP G + PP E+ Sbjct: 431 PGLPGPPGPAGPHIPPSDEI 450 Score = 72.8 bits (177), Expect = 8e-13 Identities = 92/287 (32%), Positives = 103/287 (35%), Gaps = 72/287 (25%) Query: 176 QSGQMSGEGKAGPPG------GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGG-PPP 228 + GQ G GPPG G+ +G G PG G FPG GP G P P Sbjct: 329 EKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE-KGERGFPGIQGPPGLPGP 387 Query: 229 PFPAGQTPPRPP--------LGPPGPPGPPGPPPP---GQVLPPPLAGPPNRGDRPPPPV 277 P A PP PP G GPPG P PP GQ P L GPP P P Sbjct: 388 PGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPG----PAGPH 443 Query: 278 LFPGQPFGQPPLGPLPPGPP--PPVPGYGPPPGPPPPQ------------QGPPPPPG-P 322 + P +P PPGPP P G G + GPP PG P Sbjct: 444 IPPSDEICEPG----PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499 Query: 323 FPPRPPGPLGPP--------LTLAPPPHLPGPP--PGAPP-PAPHVNPA---FFP----- 363 P PPG LG P P LPG P PGAP P P FP Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD 559 Query: 364 --------PPTNSGMPTSDSRG--PPPTDPYGRPPPYD-RGDYGPPG 399 P G+P + + P P G P +G+ GPPG Sbjct: 560 KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPG 606 Score = 71.6 bits (174), Expect = 2e-12 Identities = 61/161 (37%), Positives = 67/161 (41%), Gaps = 27/161 (16%) Query: 183 EGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLG 242 +G GPPG P G G PG +PG FPG GP G P AG +G Sbjct: 1305 KGDQGPPGLQGNPGRP-GLNGMKGDPG-LPGVPGFPGMKGPSGVPGS--AGPEGEPGLIG 1360 Query: 243 PPGPPGPPGPPPPGQVL-----PPPLAGPPNRGDRPPP--PVLFPGQ--PFGQPPLGPLP 293 PPGPPG PGP ++ PP + G P P P P PG P G P LP Sbjct: 1361 PPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP 1420 Query: 294 -----------PGPP--PPVPGYGPPPGPPPPQQGPPPPPG 321 PG P P G PPGP QGPP PPG Sbjct: 1421 GFDGAGGRKGDPGLPGQPGTRGLDGPPGPDG-LQGPPGPPG 1460 Score = 46.6 bits (109), Expect = 6e-05 Identities = 36/108 (33%), Positives = 42/108 (38%), Gaps = 19/108 (17%) Query: 176 QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQT 235 + G + G G PG S ++ +G G PG PG PGP GP G P P Sbjct: 1355 EPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQ-PGLKGLPGPQGPQGLPGPTGPPGD 1413 Query: 236 PPRPPL----------------GPPGPPGPPGPPPPGQVLPPPLAGPP 267 P R L G PG G GPP P + PP GPP Sbjct: 1414 PGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPP--GPP 1459 Score = 43.9 bits (102), Expect = 4e-04 Identities = 37/91 (40%), Positives = 40/91 (43%), Gaps = 19/91 (20%) Query: 183 EGKAGPPG-----GSSRAAFPQGGRGRGRFPGAV-----PGGDRFPGPAGPGGPP--PPF 230 +G AGPPG G PQG +G PG PG + PG G GG P Sbjct: 1378 KGDAGPPGIPGQPGLKGLPGPQGPQG---LPGPTGPPGDPGRNGLPGFDGAGGRKGDPGL 1434 Query: 231 PAGQTPPRPPLGPPGPPG---PPGPPPPGQV 258 P GQ R GPPGP G PPGPP V Sbjct: 1435 P-GQPGTRGLDGPPGPDGLQGPPGPPGTSSV 1464 Score = 40.4 bits (93), Expect = 0.004 Identities = 28/73 (38%), Positives = 29/73 (39%), Gaps = 2/73 (2%) Query: 178 GQMSGEGKAGPPG--GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQT 235 GQ +G GP G G P G GR PG G R P PG P G Sbjct: 1388 GQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPP 1447 Query: 236 PPRPPLGPPGPPG 248 P GPPGPPG Sbjct: 1448 GPDGLQGPPGPPG 1460 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 107 bits (266), Expect = 4e-23 Identities = 104/287 (36%), Positives = 117/287 (40%), Gaps = 72/287 (25%) Query: 178 GQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP---PPFPAGQ 234 GQ G GP G F +G RG P PG PG GP GPP PP P G+ Sbjct: 579 GQDGLPGLPGPKGEPGGITF-KGERG----PPGNPGLPGLPGNIGPMGPPGFGPPGPVGE 633 Query: 235 TPPRPPLGPPGPPGPPGPP-PPGQVLPPP----LAGPPNR-GDRPPPPVLFPGQPF--GQ 286 + G PG PG PGP PGQ + P L G P R GD V PG P GQ Sbjct: 634 KGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGD-----VGLPGDPGLPGQ 688 Query: 287 PPLGPLP-------------PGPPPP--VPGYGPPPGPPPPQ-----QGPPPPPG----- 321 P L +P PGPP P PG PPG P +GPP PPG Sbjct: 689 PGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPK 748 Query: 322 -------PFPPRPPGPLGPPLTLAPP-----PHLPGPP-----PGAPPPAPHVNPAFFPP 364 P PP PPG G L P P PGPP G P P V P P Sbjct: 749 GEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPG 808 Query: 365 PTN-SGMPTSDSRGPPP----TDPYGRPP----PYDRGDYGPPGREM 402 P G+P +GPP P G+P P ++GD GPPG ++ Sbjct: 809 PMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV 855 Score = 102 bits (253), Expect = 1e-21 Identities = 94/267 (35%), Positives = 109/267 (40%), Gaps = 61/267 (22%) Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG----------------PGG 225 G G GPPG + G +G G PG +PG PGP G PG Sbjct: 1188 GFGNPGPPGLPGLS----GQKGDGGLPG-IPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS 1242 Query: 226 PPPPF--PAGQTPPRPPLGPPGPPGPPGPP-------------PPGQVLPPPLAGPPN-R 269 P P P G P+ P G PG PGP GPP PGQ P L G P + Sbjct: 1243 PGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQ---PGLPGLPGLK 1299 Query: 270 GDRPPPPVLFPGQPFGQPPLGPLPPGPP-PPVPGYGPPPGPP--PPQQGPPPPPG----P 322 GD+ PP + G P G+P L + P P VPG+ GP P GP PG P Sbjct: 1300 GDQGPPGL--QGNP-GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPP 1356 Query: 323 FPPRPPGPLGPPLTL---APPPHLPGPPPGAPPPAPHVNPAFFPPPT-------NSGMPT 372 PP PGP G + + A PP +PG P P P P P PT +G+P Sbjct: 1357 GPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQ-GPQGLPGPTGPPGDPGRNGLPG 1415 Query: 373 SDSRGPPPTDPYGRPPPYDRGDYGPPG 399 D G DP P RG GPPG Sbjct: 1416 FDGAGGRKGDPGLPGQPGTRGLDGPPG 1442 Score = 99.0 bits (245), Expect = 1e-20 Identities = 92/252 (36%), Positives = 102/252 (40%), Gaps = 53/252 (21%) Query: 189 PGGSSRAAFPQGGRGRGRFPGAV--PGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGP 246 PG + +G +G FPG PG FPGP GP GP GQ GPPGP Sbjct: 34 PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGP-----RGQKGDDGIPGPPGP 88 Query: 247 PGPPGPPP-PGQVLPPPLAGPPNRGDRPPPPVL-----------FPGQPFGQPPLGPLPP 294 G GPP PG P L G P P P + FPG P G P L PP Sbjct: 89 KGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSP-GFPGLQG-PP 146 Query: 295 GPPPPVPGYGPPPGP------PPPQQGP--PPPPG----PFPPRPPGPLGPPLTLAPPPH 342 G PP +PG PG P P+ P P PPG P P PGP+GPP PP Sbjct: 147 G-PPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPP----GPPG 201 Query: 343 LPGP--PPGAPPPAPHVNPAFFPPPTNSG-MPTSDSRGPPPTDPYGRPP----------- 388 L GP PPG P P ++ F P G GPP + P Sbjct: 202 LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261 Query: 389 -PYDRGDYGPPG 399 P DRG GPPG Sbjct: 262 LPGDRGPPGPPG 273 Score = 97.8 bits (242), Expect = 2e-20 Identities = 90/240 (37%), Positives = 101/240 (42%), Gaps = 38/240 (15%) Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAV-----PGGDRFPGPAGPGG---PPPPFPAG 233 G G GPPG P G G PG + PG FPGP G G P PP P G Sbjct: 705 GIGLPGPPGPKGFPGIP-GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPG 763 Query: 234 QTPPRPPLGPPGP---PGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLG 290 + LGP G PGPPG PPG+ L GP +GD P P P G P +G Sbjct: 764 LPGFKGALGPKGDRGFPGPPG--PPGRTGLDGLPGP--KGDVGPNGQPGPMGPPGLPGIG 819 Query: 291 PLPPGPPPPVPGYGPPPGPP-----PPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPG 345 P PP +PG P G P P ++G P PPG P PPG G P P PG Sbjct: 820 VQGPPGPPGIPG---PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSP----GIPGAPG 872 Query: 346 P--PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMD 403 P PPG+P + F P T M GPP P G P G G PG + D Sbjct: 873 PIGPPGSPGLPGKAGASGF-PGTKGEMGMMGPPGPP--GPLGIP-----GRSGVPGLKGD 924 Score = 91.7 bits (226), Expect = 2e-18 Identities = 108/335 (32%), Positives = 117/335 (34%), Gaps = 109/335 (32%) Query: 176 QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAV--PG-----GDR-FPGPAGPGGPP 227 Q G G GPPG P+G G PG + PG GD FPGP G GPP Sbjct: 992 QPGLSGQPGLPGPPG-------PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPP 1044 Query: 228 PPFPAGQTPPRP------------------------PLGPPGPPGPPGPPP-PGQVLPPP 262 P P P P G PG PG PG P G V P Sbjct: 1045 GPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPG 1104 Query: 263 LAGPPNRGDRPPPPVL--FPGQP-------FGQPPLGPLPPGPPPPVPGYGPP--PGPP- 310 L G P P L FPG P PP P PG P PV G G P PGPP Sbjct: 1105 LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164 Query: 311 ----PPQQGPPPPPG------------PFPPRPPGPLGPPLTLAPP-----PHLPGP--- 346 P Q G P P G P PP PG G P P LPGP Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGE 1224 Query: 347 --------------PPGAPPPA---PHVNPAFFPPPTNSGMPTSDSRGPP---------- 379 PPG+P PA P NP PP G+P + GPP Sbjct: 1225 PGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPE--GPPGLPGNGGIKG 1282 Query: 380 ----PTDPYGRPPPYDRGDYGPPGREMDTARTPLS 410 P P P +GD GPPG + + R L+ Sbjct: 1283 EKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLN 1317 Score = 91.3 bits (225), Expect = 2e-18 Identities = 93/271 (34%), Positives = 105/271 (38%), Gaps = 56/271 (20%) Query: 174 TTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG----PGGPPPP 229 T + G G GPPG G +G PG +PG GP G PG P P Sbjct: 937 TGEKGSKGEPGLPGPPGPMDPNLL--GSKGEKGEPG-LPGIPGVSGPKGYQGLPGDPGQP 993 Query: 230 FPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGP--------PNRGDRPPPPVLFPG 281 +GQ P GP G PG PG PG + PP L G P + PP P PG Sbjct: 994 GLSGQPGLPGPPGPKGNPGLPG--QPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPG 1051 Query: 282 QPFGQPPLG----------------PLPPGP--PPPVPGY----------GPP--PGPP- 310 QP G P L P PGP P +PGY G P PG P Sbjct: 1052 QP-GSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPG 1110 Query: 311 -PPQQGPPPPPG-PFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNS 368 P +G P PG P P PPGP G ++ PP PG P P +P PP Sbjct: 1111 TPGAKGQPGLPGFPGTPGPPGPKG----ISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEK 1166 Query: 369 GMPTSDSRGPPPTDPYGRPPPYDRGDYGPPG 399 G P D P P G P G+ GPPG Sbjct: 1167 GKPGQDGI-PGPAGQKGEPGQPGFGNPGPPG 1196 Score = 80.9 bits (198), Expect = 3e-15 Identities = 87/255 (34%), Positives = 99/255 (38%), Gaps = 43/255 (16%) Query: 178 GQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPG-----AVPGGDRFPGPAG-------PGG 225 G+M G GPPG P G GR PG + G PGP G PG Sbjct: 896 GEMGMMGPPGPPG-------PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGL 948 Query: 226 PPPPFPA-----GQTPPRPPLGPPGPPGPPGPPP----PGQVLPPPLAGPPNRGDRPPPP 276 P PP P G + G PG PG GP PG P L+G P PP P Sbjct: 949 PGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL-PGPPGP 1007 Query: 277 VLFPGQPFGQPPLGPLPPGPPPPVPGYGPP-----PGPPPPQQGPPPPPGPFPPRPPGPL 331 PG P GQP L PPG + G P GPP P P P P P G Sbjct: 1008 KGNPGLP-GQPGLIG-PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065 Query: 332 GPP-LTLAPPPHLPGP--PPGAP--PPAPHVNPAFFPP--PTNSGMPTSDSRGPPPTDPY 384 G P ++ P LPGP PG P P P + + P P G P + + P P Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG 1125 Query: 385 GRPPPYDRGDYGPPG 399 PP +G GPPG Sbjct: 1126 TPGPPGPKGISGPPG 1140 Score = 79.3 bits (194), Expect = 8e-15 Identities = 97/320 (30%), Positives = 110/320 (34%), Gaps = 111/320 (34%) Query: 184 GKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG-PGGPPPPFPAGQTPPRP--- 239 G GPPG P G G PG++ PGP G PG P PP G P Sbjct: 141 GLQGPPG-------PPGIPGMKGEPGSIIMSS-LPGPKGNPGYPGPPGIQGLPGPTGIPG 192 Query: 240 PLGPPGPPG---PPGPP---------------PPGQVLPPPLAGPPN-----RGDRPPPP 276 P+GPPGPPG PPGPP P G+ L GPP + P Sbjct: 193 PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252 Query: 277 VLF----PGQPFGQPPLGPL----PPGPP---------------------------PPVP 301 V F G P + P GP PPGPP P +P Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312 Query: 302 GYGPPPGPP-----------PPQQGPPPPPGPFPPRP--------PGPLGPP-------- 334 G PG P GPP PPG PRP G +G P Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372 Query: 335 ---LTLAPPPHLPGPPPGA--PPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP-- 387 + PP LPGPP A PP P P + G P GPP D G+P Sbjct: 373 RGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLD--GQPGA 430 Query: 388 -----PPYDRGDYGPPGREM 402 PP G + PP E+ Sbjct: 431 PGLPGPPGPAGPHIPPSDEI 450 Score = 72.8 bits (177), Expect = 8e-13 Identities = 92/287 (32%), Positives = 103/287 (35%), Gaps = 72/287 (25%) Query: 176 QSGQMSGEGKAGPPG------GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGG-PPP 228 + GQ G GPPG G+ +G G PG G FPG GP G P P Sbjct: 329 EKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE-KGERGFPGIQGPPGLPGP 387 Query: 229 PFPAGQTPPRPP--------LGPPGPPGPPGPPPP---GQVLPPPLAGPPNRGDRPPPPV 277 P A PP PP G GPPG P PP GQ P L GPP P P Sbjct: 388 PGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPG----PAGPH 443 Query: 278 LFPGQPFGQPPLGPLPPGPP--PPVPGYGPPPGPPPPQ------------QGPPPPPG-P 322 + P +P PPGPP P G G + GPP PG P Sbjct: 444 IPPSDEICEPG----PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499 Query: 323 FPPRPPGPLGPP--------LTLAPPPHLPGPP--PGAPP-PAPHVNPA---FFP----- 363 P PPG LG P P LPG P PGAP P P FP Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD 559 Query: 364 --------PPTNSGMPTSDSRG--PPPTDPYGRPPPYD-RGDYGPPG 399 P G+P + + P P G P +G+ GPPG Sbjct: 560 KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPG 606 Score = 71.6 bits (174), Expect = 2e-12 Identities = 61/161 (37%), Positives = 67/161 (41%), Gaps = 27/161 (16%) Query: 183 EGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLG 242 +G GPPG P G G PG +PG FPG GP G P AG +G Sbjct: 1299 KGDQGPPGLQGNPGRP-GLNGMKGDPG-LPGVPGFPGMKGPSGVPGS--AGPEGEPGLIG 1354 Query: 243 PPGPPGPPGPPPPGQVL-----PPPLAGPPNRGDRPPP--PVLFPGQ--PFGQPPLGPLP 293 PPGPPG PGP ++ PP + G P P P P PG P G P LP Sbjct: 1355 PPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP 1414 Query: 294 -----------PGPP--PPVPGYGPPPGPPPPQQGPPPPPG 321 PG P P G PPGP QGPP PPG Sbjct: 1415 GFDGAGGRKGDPGLPGQPGTRGLDGPPGPDG-LQGPPGPPG 1454 Score = 46.6 bits (109), Expect = 6e-05 Identities = 36/108 (33%), Positives = 42/108 (38%), Gaps = 19/108 (17%) Query: 176 QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQT 235 + G + G G PG S ++ +G G PG PG PGP GP G P P Sbjct: 1349 EPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQ-PGLKGLPGPQGPQGLPGPTGPPGD 1407 Query: 236 PPRPPL----------------GPPGPPGPPGPPPPGQVLPPPLAGPP 267 P R L G PG G GPP P + PP GPP Sbjct: 1408 PGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPP--GPP 1453 Score = 43.9 bits (102), Expect = 4e-04 Identities = 37/91 (40%), Positives = 40/91 (43%), Gaps = 19/91 (20%) Query: 183 EGKAGPPG-----GSSRAAFPQGGRGRGRFPGAV-----PGGDRFPGPAGPGGPP--PPF 230 +G AGPPG G PQG +G PG PG + PG G GG P Sbjct: 1372 KGDAGPPGIPGQPGLKGLPGPQGPQG---LPGPTGPPGDPGRNGLPGFDGAGGRKGDPGL 1428 Query: 231 PAGQTPPRPPLGPPGPPG---PPGPPPPGQV 258 P GQ R GPPGP G PPGPP V Sbjct: 1429 P-GQPGTRGLDGPPGPDGLQGPPGPPGTSSV 1458 Score = 40.4 bits (93), Expect = 0.004 Identities = 28/73 (38%), Positives = 29/73 (39%), Gaps = 2/73 (2%) Query: 178 GQMSGEGKAGPPG--GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQT 235 GQ +G GP G G P G GR PG G R P PG P G Sbjct: 1382 GQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPP 1441 Query: 236 PPRPPLGPPGPPG 248 P GPPGPPG Sbjct: 1442 GPDGLQGPPGPPG 1454 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 107 bits (266), Expect = 4e-23 Identities = 104/287 (36%), Positives = 117/287 (40%), Gaps = 72/287 (25%) Query: 178 GQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP---PPFPAGQ 234 GQ G GP G F +G RG P PG PG GP GPP PP P G+ Sbjct: 579 GQDGLPGLPGPKGEPGGITF-KGERG----PPGNPGLPGLPGNIGPMGPPGFGPPGPVGE 633 Query: 235 TPPRPPLGPPGPPGPPGPP-PPGQVLPPP----LAGPPNR-GDRPPPPVLFPGQPF--GQ 286 + G PG PG PGP PGQ + P L G P R GD V PG P GQ Sbjct: 634 KGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGD-----VGLPGDPGLPGQ 688 Query: 287 PPLGPLP-------------PGPPPP--VPGYGPPPGPPPPQ-----QGPPPPPG----- 321 P L +P PGPP P PG PPG P +GPP PPG Sbjct: 689 PGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPK 748 Query: 322 -------PFPPRPPGPLGPPLTLAPP-----PHLPGPP-----PGAPPPAPHVNPAFFPP 364 P PP PPG G L P P PGPP G P P V P P Sbjct: 749 GEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPG 808 Query: 365 PTN-SGMPTSDSRGPPP----TDPYGRPP----PYDRGDYGPPGREM 402 P G+P +GPP P G+P P ++GD GPPG ++ Sbjct: 809 PMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDV 855 Score = 99.0 bits (245), Expect = 1e-20 Identities = 92/252 (36%), Positives = 102/252 (40%), Gaps = 53/252 (21%) Query: 189 PGGSSRAAFPQGGRGRGRFPGAV--PGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGP 246 PG + +G +G FPG PG FPGP GP GP GQ GPPGP Sbjct: 34 PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGP-----RGQKGDDGIPGPPGP 88 Query: 247 PGPPGPPP-PGQVLPPPLAGPPNRGDRPPPPVL-----------FPGQPFGQPPLGPLPP 294 G GPP PG P L G P P P + FPG P G P L PP Sbjct: 89 KGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSP-GFPGLQG-PP 146 Query: 295 GPPPPVPGYGPPPGP------PPPQQGP--PPPPG----PFPPRPPGPLGPPLTLAPPPH 342 G PP +PG PG P P+ P P PPG P P PGP+GPP PP Sbjct: 147 G-PPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPP----GPPG 201 Query: 343 LPGP--PPGAPPPAPHVNPAFFPPPTNSG-MPTSDSRGPPPTDPYGRPP----------- 388 L GP PPG P P ++ F P G GPP + P Sbjct: 202 LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261 Query: 389 -PYDRGDYGPPG 399 P DRG GPPG Sbjct: 262 LPGDRGPPGPPG 273 Score = 97.8 bits (242), Expect = 2e-20 Identities = 90/240 (37%), Positives = 101/240 (42%), Gaps = 38/240 (15%) Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPGAV-----PGGDRFPGPAGPGG---PPPPFPAG 233 G G GPPG P G G PG + PG FPGP G G P PP P G Sbjct: 705 GIGLPGPPGPKGFPGIP-GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPG 763 Query: 234 QTPPRPPLGPPGP---PGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLG 290 + LGP G PGPPG PPG+ L GP +GD P P P G P +G Sbjct: 764 LPGFKGALGPKGDRGFPGPPG--PPGRTGLDGLPGP--KGDVGPNGQPGPMGPPGLPGIG 819 Query: 291 PLPPGPPPPVPGYGPPPGPP-----PPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPG 345 P PP +PG P G P P ++G P PPG P PPG G P P PG Sbjct: 820 VQGPPGPPGIPG---PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSP----GIPGAPG 872 Query: 346 P--PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMD 403 P PPG+P + F P T M GPP P G P G G PG + D Sbjct: 873 PIGPPGSPGLPGKAGASGF-PGTKGEMGMMGPPGPP--GPLGIP-----GRSGVPGLKGD 924 Score = 97.8 bits (242), Expect = 2e-20 Identities = 94/267 (35%), Positives = 108/267 (40%), Gaps = 58/267 (21%) Query: 182 GEGKAGPPGGSSRAAFPQGGRGRGRFPG-----------AVPGGDRFPGPAGPGGPP-PP 229 G G GPPG + G +G G PG PG FPG GP GPP P Sbjct: 1188 GFGNPGPPGLPGLS----GQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSP 1243 Query: 230 FPAGQTPPRPPLGPPGPPGPPG-PPPPGQVLPPPLAG-------------------PPNR 269 PA + P P GP GPPG PG PG PP L G P + Sbjct: 1244 GPALEGPKGNP-GPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLK 1302 Query: 270 GDRPPPPVLFPGQPFGQPPLGPLPPGPP-PPVPGYGPPPGPP--PPQQGPPPPPG----P 322 GD+ PP + G P G+P L + P P VPG+ GP P GP PG P Sbjct: 1303 GDQGPPGL--QGNP-GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPP 1359 Query: 323 FPPRPPGPLGPPLTL---APPPHLPGPPPGAPPPAPHVNPAFFPPPT-------NSGMPT 372 PP PGP G + + A PP +PG P P P P P PT +G+P Sbjct: 1360 GPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQ-GPQGLPGPTGPPGDPGRNGLPG 1418 Query: 373 SDSRGPPPTDPYGRPPPYDRGDYGPPG 399 D G DP P RG GPPG Sbjct: 1419 FDGAGGRKGDPGLPGQPGTRGLDGPPG 1445 Score = 95.9 bits (237), Expect = 9e-20 Identities = 97/272 (35%), Positives = 106/272 (38%), Gaps = 62/272 (22%) Query: 180 MSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAV--PGGDRFPGPAGPGGPP--PPFPAGQT 235 +S G G PG P G G G+V PG PG G G P P FP Sbjct: 1070 ISSIGLPGLPGPKGEPGLP-GYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPG 1128 Query: 236 PPRPP--LGPPGPPGPPGPPPP-------GQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQ 286 PP P GPPG PG PG P P GQ PP G P + D P P G+P GQ Sbjct: 1129 PPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQ-DGIPGPAGQKGEP-GQ 1186 Query: 287 PPLG-PLPPGPP-----------PPVPGYGPPPGPP--------PPQQGPPPPPGPFPPR 326 P G P PPG P P +PG PGP P QGPP PPG P Sbjct: 1187 PGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPA 1246 Query: 327 PPGPLGPPLTLAPPPH-----LPGP--PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPP 379 GP G P PP LPGP PPG P N N G P Sbjct: 1247 LEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPG-----NGGIKGEKGNPGQP-------- 1293 Query: 380 PTDPYGRPP-PYDRGDYGPPGREMDTARTPLS 410 G P P +GD GPPG + + R L+ Sbjct: 1294 -----GLPGLPGLKGDQGPPGLQGNPGRPGLN 1320 Score = 91.3 bits (225), Expect = 2e-18 Identities = 93/271 (34%), Positives = 105/271 (38%), Gaps = 56/271 (20%) Query: 174 TTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG----PGGPPPP 229 T + G G GPPG G +G PG +PG GP G PG P P Sbjct: 937 TGEKGSKGEPGLPGPPGPMDPNLL--GSKGEKGEPG-LPGIPGVSGPKGYQGLPGDPGQP 993 Query: 230 FPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGP--------PNRGDRPPPPVLFPG 281 +GQ P GP G PG PG PG + PP L G P + PP P PG Sbjct: 994 GLSGQPGLPGPPGPKGNPGLPG--QPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPG 1051 Query: 282 QPFGQPPLG----------------PLPPGP--PPPVPGY----------GPP--PGPP- 310 QP G P L P PGP P +PGY G P PG P Sbjct: 1052 QP-GSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPG 1110 Query: 311 -PPQQGPPPPPG-PFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNS 368 P +G P PG P P PPGP G ++ PP PG P P +P PP Sbjct: 1111 TPGAKGQPGLPGFPGTPGPPGPKG----ISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEK 1166 Query: 369 GMPTSDSRGPPPTDPYGRPPPYDRGDYGPPG 399 G P D P P G P G+ GPPG Sbjct: 1167 GKPGQDGI-PGPAGQKGEPGQPGFGNPGPPG 1196 Score = 90.1 bits (222), Expect = 5e-18 Identities = 99/283 (34%), Positives = 102/283 (36%), Gaps = 70/283 (24%) Query: 176 QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAV--PG-----GDR-FPGPAGPGGPP 227 Q G G GPPG P+G G PG + PG GD FPGP G GPP Sbjct: 992 QPGLSGQPGLPGPPG-------PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPP 1044 Query: 228 PPFPAGQTPPRP------------------------PLGPPGPPGPPGPPP-PGQVLPPP 262 P P P P G PG PG PG P G V P Sbjct: 1045 GPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPG 1104 Query: 263 LAGPPNRGDRPPPPVL--FPGQP-------FGQPPLGPLPPGPPPPVPGYGPP--PGPP- 310 L G P P L FPG P PP P PG P PV G G P PGPP Sbjct: 1105 LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164 Query: 311 ----PPQQGPPPPPGP--FPPRP----PGPLGPPLTLAPPPH--LPGPPPGAPPPAPHVN 358 P Q G P P G P +P PGP G P LPG P P P Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGE 1224 Query: 359 PAFFPPPTNSGMP-TSDSRGPPPTDPYGRPPPYDRGDYGPPGR 400 P F P G P S GP P G P G GPPGR Sbjct: 1225 PGFHGFPGVQGPPGPPGSPGPALEGPKGNP-----GPQGPPGR 1262 Score = 83.6 bits (205), Expect = 4e-16 Identities = 101/279 (36%), Positives = 108/279 (38%), Gaps = 68/279 (24%) Query: 176 QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDR--FPGPAGPGGPPP----P 229 Q G G GPPG + P G G PG V GG PGP G G P P Sbjct: 1117 QPGLPGFPGTPGPPGPKGISG-PPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIP 1175 Query: 230 FPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRP--PPPVLFPGQPFGQP 287 PAGQ G PG PG P PPG P L+G G P P PG P G+P Sbjct: 1176 GPAGQK------GEPGQPGFGNPGPPGL---PGLSGQKGDGGLPGIPGNPGLPG-PKGEP 1225 Query: 288 -----PLGPLPPGPP-PPVPGYGPPPGPPPPQQGPPPPPG----PFPPRPPG-------- 329 P PPGPP P P P G P P QGPP PG P P PPG Sbjct: 1226 GFHGFPGVQGPPGPPGSPGPALEGPKGNPGP-QGPPGRPGFQGLPGPEGPPGLPGNGGIK 1284 Query: 330 -----PLGPPLTLAP-------PPHLPGPP--PG-----APPPAPHVNPAFFPPPTNSGM 370 P P L P PP L G P PG P P V P F SG+ Sbjct: 1285 GEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGV-PGFPGMKGPSGV 1343 Query: 371 P-TSDSRGPP----PTDPYGRPPPYD-----RGDYGPPG 399 P ++ G P P P G P P +GD GPPG Sbjct: 1344 PGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPG 1382 Score = 80.9 bits (198), Expect = 3e-15 Identities = 87/255 (34%), Positives = 99/255 (38%), Gaps = 43/255 (16%) Query: 178 GQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPG-----AVPGGDRFPGPAG-------PGG 225 G+M G GPPG P G GR PG + G PGP G PG Sbjct: 896 GEMGMMGPPGPPG-------PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGL 948 Query: 226 PPPPFPA-----GQTPPRPPLGPPGPPGPPGPPP----PGQVLPPPLAGPPNRGDRPPPP 276 P PP P G + G PG PG GP PG P L+G P PP P Sbjct: 949 PGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL-PGPPGP 1007 Query: 277 VLFPGQPFGQPPLGPLPPGPPPPVPGYGPP-----PGPPPPQQGPPPPPGPFPPRPPGPL 331 PG P GQP L PPG + G P GPP P P P P P G Sbjct: 1008 KGNPGLP-GQPGLIG-PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065 Query: 332 GPP-LTLAPPPHLPGP--PPGAP--PPAPHVNPAFFPP--PTNSGMPTSDSRGPPPTDPY 384 G P ++ P LPGP PG P P P + + P P G P + + P P Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG 1125 Query: 385 GRPPPYDRGDYGPPG 399 PP +G GPPG Sbjct: 1126 TPGPPGPKGISGPPG 1140 Score = 79.3 bits (194), Expect = 8e-15 Identities = 97/320 (30%), Positives = 110/320 (34%), Gaps = 111/320 (34%) Query: 184 GKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG-PGGPPPPFPAGQTPPRP--- 239 G GPPG P G G PG++ PGP G PG P PP G P Sbjct: 141 GLQGPPG-------PPGIPGMKGEPGSIIMSS-LPGPKGNPGYPGPPGIQGLPGPTGIPG 192 Query: 240 PLGPPGPPG---PPGPP---------------PPGQVLPPPLAGPPN-----RGDRPPPP 276 P+GPPGPPG PPGPP P G+ L GPP + P Sbjct: 193 PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252 Query: 277 VLF----PGQPFGQPPLGPL----PPGPP---------------------------PPVP 301 V F G P + P GP PPGPP P +P Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312 Query: 302 GYGPPPGPP-----------PPQQGPPPPPGPFPPRP--------PGPLGPP-------- 334 G PG P GPP PPG PRP G +G P Sbjct: 313 GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372 Query: 335 ---LTLAPPPHLPGPPPGA--PPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP-- 387 + PP LPGPP A PP P P + G P GPP D G+P Sbjct: 373 RGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLD--GQPGA 430 Query: 388 -----PPYDRGDYGPPGREM 402 PP G + PP E+ Sbjct: 431 PGLPGPPGPAGPHIPPSDEI 450 Score = 72.8 bits (177), Expect = 8e-13 Identities = 92/287 (32%), Positives = 103/287 (35%), Gaps = 72/287 (25%) Query: 176 QSGQMSGEGKAGPPG------GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGG-PPP 228 + GQ G GPPG G+ +G G PG G FPG GP G P P Sbjct: 329 EKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE-KGERGFPGIQGPPGLPGP 387 Query: 229 PFPAGQTPPRPP--------LGPPGPPGPPGPPPP---GQVLPPPLAGPPNRGDRPPPPV 277 P A PP PP G GPPG P PP GQ P L GPP P P Sbjct: 388 PGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPG----PAGPH 443 Query: 278 LFPGQPFGQPPLGPLPPGPP--PPVPGYGPPPGPPPPQ------------QGPPPPPG-P 322 + P +P PPGPP P G G + GPP PG P Sbjct: 444 IPPSDEICEPG----PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499 Query: 323 FPPRPPGPLGPP--------LTLAPPPHLPGPP--PGAPP-PAPHVNPA---FFP----- 363 P PPG LG P P LPG P PGAP P P FP Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD 559 Query: 364 --------PPTNSGMPTSDSRG--PPPTDPYGRPPPYD-RGDYGPPG 399 P G+P + + P P G P +G+ GPPG Sbjct: 560 KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPG 606 Score = 71.6 bits (174), Expect = 2e-12 Identities = 61/161 (37%), Positives = 67/161 (41%), Gaps = 27/161 (16%) Query: 183 EGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLG 242 +G GPPG P G G PG +PG FPG GP G P AG +G Sbjct: 1302 KGDQGPPGLQGNPGRP-GLNGMKGDPG-LPGVPGFPGMKGPSGVPGS--AGPEGEPGLIG 1357 Query: 243 PPGPPGPPGPPPPGQVL-----PPPLAGPPNRGDRPPP--PVLFPGQ--PFGQPPLGPLP 293 PPGPPG PGP ++ PP + G P P P P PG P G P LP Sbjct: 1358 PPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP 1417 Query: 294 -----------PGPP--PPVPGYGPPPGPPPPQQGPPPPPG 321 PG P P G PPGP QGPP PPG Sbjct: 1418 GFDGAGGRKGDPGLPGQPGTRGLDGPPGPDG-LQGPPGPPG 1457 Score = 46.6 bits (109), Expect = 6e-05 Identities = 36/108 (33%), Positives = 42/108 (38%), Gaps = 19/108 (17%) Query: 176 QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQT 235 + G + G G PG S ++ +G G PG PG PGP GP G P P Sbjct: 1352 EPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQ-PGLKGLPGPQGPQGLPGPTGPPGD 1410 Query: 236 PPRPPL----------------GPPGPPGPPGPPPPGQVLPPPLAGPP 267 P R L G PG G GPP P + PP GPP Sbjct: 1411 PGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPP--GPP 1456 Score = 43.9 bits (102), Expect = 4e-04 Identities = 37/91 (40%), Positives = 40/91 (43%), Gaps = 19/91 (20%) Query: 183 EGKAGPPG-----GSSRAAFPQGGRGRGRFPGAV-----PGGDRFPGPAGPGGPP--PPF 230 +G AGPPG G PQG +G PG PG + PG G GG P Sbjct: 1375 KGDAGPPGIPGQPGLKGLPGPQGPQG---LPGPTGPPGDPGRNGLPGFDGAGGRKGDPGL 1431 Query: 231 PAGQTPPRPPLGPPGPPG---PPGPPPPGQV 258 P GQ R GPPGP G PPGPP V Sbjct: 1432 P-GQPGTRGLDGPPGPDGLQGPPGPPGTSSV 1461 Score = 40.4 bits (93), Expect = 0.004 Identities = 28/73 (38%), Positives = 29/73 (39%), Gaps = 2/73 (2%) Query: 178 GQMSGEGKAGPPG--GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQT 235 GQ +G GP G G P G GR PG G R P PG P G Sbjct: 1385 GQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPP 1444 Query: 236 PPRPPLGPPGPPG 248 P GPPGPPG Sbjct: 1445 GPDGLQGPPGPPG 1457 >gi|150417989 cyclin K isoform 1 [Homo sapiens] Length = 580 Score = 106 bits (264), Expect = 6e-23 Identities = 79/210 (37%), Positives = 88/210 (41%), Gaps = 49/210 (23%) Query: 226 PPPPFPAGQT--PPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPP---PPVLFP 280 PPP P +T PP PP PP PP G+ PP GP + D P PP P Sbjct: 351 PPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPP---GPVDATDLPKVQIPPPAHP 407 Query: 281 GQPFGQPPLGPLPPGPPPPVP-----------------GY----------GPPPGPPPPQ 313 P QPP PLP PPPP P GY GP G PP Sbjct: 408 A-PVHQPP--PLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPA 464 Query: 314 QGPPP----PPGPFPPR-PPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNS 368 GPP P +PP PP P+ PP PPP +P P PG PPP P NP F PPP Sbjct: 465 YGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPR- 523 Query: 369 GMPTSDSRGPPPTDPYGRPPPYDRGDYGPP 398 +P + + P P G PP Y PP Sbjct: 524 -LPPTHAVPPHPPPGLGLPP----ASYPPP 548 Score = 99.4 bits (246), Expect = 8e-21 Identities = 81/217 (37%), Positives = 88/217 (40%), Gaps = 49/217 (22%) Query: 208 PGAVPGGDRFPGPAGP-GGPPPPFPAGQTP-PRPPLGPPGPPGPPGPPPPGQVLPPP--- 262 P A P DR P A G PP P T P+ + PP P P PPP PPP Sbjct: 366 PPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPP 425 Query: 263 -------------LAGP-------------PNRGDRPP---PPVLFPGQPFGQPPLGPLP 293 ++G P+ G PP PP P P PP P P Sbjct: 426 SSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPP 485 Query: 294 PGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPR-PPGPLGPPLTLAPPPHLPGPPPGAP- 351 P PPPP PPP PPP G PPPP + P PP P P T A PPH PPPG Sbjct: 486 PVPPPPASF--PPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPH---PPPGLGL 540 Query: 352 PPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPP 388 PPA + PA P G P PPP P G PP Sbjct: 541 PPASYPPPAVPP----GGQPPV----PPPIPPPGMPP 569 >gi|119829187 alpha 1 type XVII collagen [Homo sapiens] Length = 1497 Score = 105 bits (262), Expect = 1e-22 Identities = 96/286 (33%), Positives = 111/286 (38%), Gaps = 78/286 (27%) Query: 178 GQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPP 237 G+ +G GP G QG RG G +PG PGP+G G P G T P Sbjct: 734 GEPGAKGAMGPAGPDGH----QGPRGEQGLTG-MPGIRGPPGPSGDPGKP-----GLTGP 783 Query: 238 RPPLGPPGPPGPPG----PPPPGQVLPPP------LAGPPNRGDRPPPPVLFPGQPFGQP 287 + P G PG PG PG P PG+++ + GPP PP + PG P Sbjct: 784 QGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPG----PPGAMGPPGPPGAPG 839 Query: 288 PLGPL-------------PPGPP----PPVPGYGPPPGP--PPPQ--QGPPPPPGPF--- 323 P GP PPGPP PP P PPGP PP + GPP PPG F Sbjct: 840 PAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSN 899 Query: 324 -------PPRPPGPLGPPLTLAPP--------PHLPG--------------PPPGAP-PP 353 PP PPGP GP PP LPG PPG P P Sbjct: 900 SETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQ 959 Query: 354 APHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPG 399 P + P G+P+ S G + Y PP G GPPG Sbjct: 960 GPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPG 1005 Score = 101 bits (252), Expect = 2e-21 Identities = 98/281 (34%), Positives = 108/281 (38%), Gaps = 62/281 (22%) Query: 178 GQMSGEGKAGPPG--GSSRAAFPQGGRG----RGRFPGAV--PGGDRFPGPAGPGGPPPP 229 G +G GPPG G P+G G RG PGAV PG GPAGP G P Sbjct: 695 GVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRG-LPGAVGEPGAKGAMGPAGPDGHQGP 753 Query: 230 FPAGQTPPRPPL-GPPGPPGPPGPP----PPGQVLPPPLAGPPNRGDRPPPPVLFPGQPF 284 P + GPPGP G PG P P G P G P P P Sbjct: 754 RGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEG 813 Query: 285 GQPPLGPLPPGPPPPVPGYGPP--PGPPPPQ-----------QGPPPPP------GPFPP 325 P PPGPP + GPP PGP P QGPP PP GP P Sbjct: 814 SSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIP 873 Query: 326 RPPGPLGPP-------------------LTLAPPPHLPGPP-----PGAPPPAPHVNPAF 361 PPGP GPP L+ PP PGPP G P P H Sbjct: 874 GPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQG 933 Query: 362 FPPPTNSGMPT--SDSRGPP-PTDPYGRPPPYDRGDYGPPG 399 P + SG + + +GPP P P G P D+GD G PG Sbjct: 934 LPGFSTSGSSSFGLNLQGPPGPPGPQG--PKGDKGDPGVPG 972 Score = 96.3 bits (238), Expect = 7e-20 Identities = 98/290 (33%), Positives = 109/290 (37%), Gaps = 64/290 (22%) Query: 176 QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP-PPFPAGQ 234 + G M G+AGPPG + G P VPG G +G GP PP P G Sbjct: 625 REGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGL 684 Query: 235 TPPRPPLGPPG------PPGPPGPP-PPGQVLPPPLAGPPN-RGDRPPPPVLFPGQPFGQ 286 R +G PG P GPPGP G+ P L G P RG P V PG Sbjct: 685 QGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRG--LPGAVGEPGAKGAM 742 Query: 287 PPLGPL-------------------PPGPP--PPVPGYGPPPGPP--------PPQQGPP 317 P GP PPGP P PG P GP P +G P Sbjct: 743 GPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEP 802 Query: 318 PPPG-------------PFPPRPPGPLGPPLTLAPPPHLPGP--PPGAPPPAPHVNPAFF 362 PG P PP PPG +GPP PP PGP P G P +N Sbjct: 803 GAPGKIVTSEGSSMLTVPGPPGPPGAMGPP----GPPGAPGPAGPAGLPGHQEVLNLQGP 858 Query: 363 P-PPTNSGMPTSDSRGPP-PTDPYGRPPPYDRGDYGPPGREMDTARTPLS 410 P PP G P GPP P P G P G GPPG + + T LS Sbjct: 859 PGPPGPRGPPGPSIPGPPGPRGPPGEGLP---GPPGPPGSFLSNSETFLS 905 Score = 87.8 bits (216), Expect = 2e-17 Identities = 113/414 (27%), Positives = 129/414 (31%), Gaps = 160/414 (38%) Query: 141 MDLLPKRELHGQNPVVTP------CNKQFLSQFEMQSRKTTQSGQMSGEGKAGP-PGGSS 193 MD + K L G P + + M RK Q +G + P P G Sbjct: 516 MDRIEKDRLQGMAPAAGADLDKIGLHSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDM 575 Query: 194 RAAFPQGGRGRGRFPGAVPGGDRFPGPAGP-------GGPPPPFPAGQTPPRPPLGP--- 243 + P+G RG PG +PG PGP GP G P P GQ P+GP Sbjct: 576 GSPGPKGDRGFPGTPG-IPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGE 634 Query: 244 -----------------PGPPGPPGPP----PPGQVLPPPLAGPPN-------------- 268 PGP GPPG P P G P GPP Sbjct: 635 AGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLP 694 Query: 269 --RGDRPP--PP--------------------------VLFPGQPFGQPPLGP------- 291 +GD+ P PP V PG P GP Sbjct: 695 GVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPR 754 Query: 292 ------------LPPGP--PPPVPGYGPPPGPP--------PPQQGPPPPPG-------- 321 PPGP P PG P GP P +G P PG Sbjct: 755 GEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGS 814 Query: 322 -----PFPPRPPGPLGPPLTLAPPPHLPGP-----------------PPGAPPPAPHVNP 359 P PP PPG +GPP PP PGP PPG P P P Sbjct: 815 SMLTVPGPPGPPGAMGPP----GPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGP 870 Query: 360 AFFPPPTNSGMPTSDSRGPPP-------------TDPYGRP-PPYDRGDYGPPG 399 + PP G P GPP + P G P PP +GD GPPG Sbjct: 871 SIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPG 924 Score = 81.6 bits (200), Expect = 2e-15 Identities = 88/261 (33%), Positives = 97/261 (37%), Gaps = 105/261 (40%) Query: 178 GQMSGEGKAGPPG------GSSRAAFPQGGRGRGRFPGAV--PGGDRFPGPAGPGGPP-- 227 G+ +G+ G PG GSS P G PGA+ PG PGPAGP G P Sbjct: 794 GRPGIKGEPGAPGKIVTSEGSSMLTVP----GPPGPPGAMGPPGPPGAPGPAGPAGLPGH 849 Query: 228 --------PPFPAG-QTPPRPPL-GPPGPPGPPG------PPPPGQVL---------PPP 262 PP P G + PP P + GPPGP GPPG P PPG L PP Sbjct: 850 QEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPG 909 Query: 263 LAGPPN-RGDRPPPPVL-------FPG------QPFGQPPLGPL-PPGPPPP-------- 299 GPP +GD+ PP PG FG GP PPGP P Sbjct: 910 PPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPG 969 Query: 300 VPG-YGPPPGP-------------PPPQQGPPPPPGPF---------------------- 323 VPG G P GP PP GPP PPG Sbjct: 970 VPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRS 1029 Query: 324 -------PPRPPGPLGPPLTL 337 PP PPGP GP T+ Sbjct: 1030 YLSGVQGPPGPPGPPGPVTTI 1050 Score = 52.4 bits (124), Expect = 1e-06 Identities = 46/147 (31%), Positives = 53/147 (36%), Gaps = 31/147 (21%) Query: 184 GKAGPPG--GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPL 241 G GPPG G P+G +G PG G G G P PP P G P+ Sbjct: 909 GPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQG---PKGDK 965 Query: 242 GPPGPPG----PPGPPPPGQVLPPPLAGPPNRGDRPPPP--VLFPGQPFGQ--------- 286 G PG PG P GP G ++GPP P PP + GQ Q Sbjct: 966 GDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSD 1025 Query: 287 -----------PPLGPLPPGPPPPVPG 302 PP P PPGP + G Sbjct: 1026 SIRSYLSGVQGPPGPPGPPGPVTTITG 1052 Score = 50.4 bits (119), Expect = 4e-06 Identities = 66/232 (28%), Positives = 83/232 (35%), Gaps = 48/232 (20%) Query: 241 LGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPP--- 297 +GP GPPGPPG G +L A +R +L G P PPGPP Sbjct: 1105 MGPRGPPGPPGASGDGSLLSLDYAELSSR-------ILSYMSSSGISIGLPGPPGPPGLP 1157 Query: 298 -------------PPVPGYGPPPGPPPPQQGPPPPPG-PFPPRPPGPLGPPLTLAPPPHL 343 G PPGPP GPP PG + L L A + Sbjct: 1158 GTSYEELLSLLRGSEFRGIVGPPGPP----GPPGIPGNVWSSISVEDLSSYLHTAGLSFI 1213 Query: 344 PGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDS--------RGPPPTDPYGRPPPYDRGDY 395 PGPP PP P P SDS P + PP G Sbjct: 1214 PGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQ 1273 Query: 396 GPPGREMDTARTPLSEAEFEEIMNRNRAISSSAISRAVSDASAGDYGSAIET 447 GPPG +R ++A + +R SSS+ S +V S+ Y S++ T Sbjct: 1274 GPPG----DSRLLSTDA------SHSRGSSSSSHSSSVRRGSS--YSSSMST 1313 Score = 49.7 bits (117), Expect = 7e-06 Identities = 52/179 (29%), Positives = 58/179 (32%), Gaps = 71/179 (39%) Query: 219 GPAGPGGPPPPFPAG-----------------QTPPRPPLGPPGPPGPPGPPPPG-QVLP 260 GP GP GPP G + +G PGPPGPPG P + L Sbjct: 1106 GPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELL 1165 Query: 261 PPLAGPPNRG----DRPPPPVLFPGQPFGQPPLGPLP-----------PGPPPPVPGYGP 305 L G RG PP P PG + + L PGPP Sbjct: 1166 SLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPP-------G 1218 Query: 306 PPGPPPPQQGPPPPPGPF------------------------------PPRPPGPLGPP 334 PPGPP P +GPP G PP PPGP GPP Sbjct: 1219 PPGPPGP-RGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPP 1276 Score = 40.0 bits (92), Expect = 0.006 Identities = 39/122 (31%), Positives = 42/122 (34%), Gaps = 33/122 (27%) Query: 214 GDRFPGPAGPGGPP-PPFPAGQTPPRPPL----------------GPPGPPGPPGPPPPG 256 G F G GP GPP PP G + GPPGPPGPPGP Sbjct: 1170 GSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGP---- 1225 Query: 257 QVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGY-GPPPGPPPPQQG 315 GPP F + L P V + PPGPP P QG Sbjct: 1226 -------RGPPGVSGALATYAAENSDSFRSELISYL---TSPDVRSFIVGPPGPPGP-QG 1274 Query: 316 PP 317 PP Sbjct: 1275 PP 1276 Score = 36.6 bits (83), Expect = 0.061 Identities = 31/93 (33%), Positives = 36/93 (38%), Gaps = 13/93 (13%) Query: 169 MQSRKTTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGG-----DRFPGPAGP 223 MQ + Q + +G G PG PQG G + A D F Sbjct: 1384 MQRQGLLQGMAYTVQGPPGQPG-------PQGPPGISKVFSAYSNVTADLMDFFQTYGAI 1436 Query: 224 GGPPPPFPAGQTP-PRPPLGPPGPPGPPGPPPP 255 GPP TP P+ GP GPPG PGPP P Sbjct: 1437 QGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGP 1469 Score = 35.8 bits (81), Expect = 0.10 Identities = 33/103 (32%), Positives = 40/103 (38%), Gaps = 9/103 (8%) Query: 153 NPVVTPCNKQFLSQFEMQSRKTTQSGQMSGEGKAGPPGGSSR-AAFPQGGRGRGRF---P 208 N + ++ Q +Q T G G GPPG S +A+ F Sbjct: 1374 NELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTY 1433 Query: 209 GAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPG 251 GA+ G PG G G P P G P P G PGPPGP G Sbjct: 1434 GAIQGP---PGQKGEMGTPGP--KGDRGPAGPPGHPGPPGPRG 1471 Score = 35.4 bits (80), Expect = 0.14 Identities = 30/92 (32%), Positives = 36/92 (39%), Gaps = 17/92 (18%) Query: 242 GPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVP 301 GPPG PGP GPP +V + ++ Q +G GPP Sbjct: 1399 GPPGQPGPQGPPGISKVF--------SAYSNVTADLMDFFQTYGAIQ------GPPGQKG 1444 Query: 302 GYGPPPGPPPPQQGPPPPPG-PFPPRPPGPLG 332 G P P +GP PPG P PP P G G Sbjct: 1445 EMGTPG--PKGDRGPAGPPGHPGPPGPRGHKG 1474 Score = 33.1 bits (74), Expect = 0.68 Identities = 26/79 (32%), Positives = 31/79 (39%), Gaps = 24/79 (30%) Query: 218 PGPAGPGGPP--------------------PPFPAGQTPP--RPPLGPPGPPGPPGPP-P 254 PG GP GPP + A Q PP + +G PGP G GP P Sbjct: 1401 PGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGP 1460 Query: 255 PGQVLPP-PLAGPPNRGDR 272 PG PP P +GD+ Sbjct: 1461 PGHPGPPGPRGHKGEKGDK 1479 Score = 33.1 bits (74), Expect = 0.68 Identities = 23/54 (42%), Positives = 24/54 (44%), Gaps = 18/54 (33%) Query: 198 PQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPG 251 P G +G PG P GDR GPAGP G P GPPGP G G Sbjct: 1439 PPGQKGEMGTPG--PKGDR--GPAGPPGHP--------------GPPGPRGHKG 1474 >gi|122937496 WAS/WASL interacting protein family, member 3 [Homo sapiens] Length = 483 Score = 105 bits (261), Expect = 1e-22 Identities = 89/265 (33%), Positives = 103/265 (38%), Gaps = 62/265 (23%) Query: 189 PGGSSRAAFPQGGRGRG------RFPGAVPGGDRFPGPAGP--GGPPPPFPAGQT-PPRP 239 P G A + G+G G R P G P PA P G A +T PPRP Sbjct: 111 PAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIP-PASPRLGNTSEAHGAARTAPPRP 169 Query: 240 PLGPPGPPGPPGPPPPGQVLPPPL----------AGPPNRGDRPPPPVLFPGQPFGQPPL 289 + P PP PP PPPP LPPPL PP + PV+ P P PP Sbjct: 170 NVPAPPPPTPPPPPPP---LPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPP 226 Query: 290 GPLPPGPPPPVPGYGP---------------PPGPPPPQQGPP--------PPPGPF--- 323 P PP PPP+P PP PPP PP P P Sbjct: 227 PPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDA 286 Query: 324 --PPRPPGPLGPPLTLAPPPHLPGPP-PG------APPPAPHVNPAFFPPPTNSGMPTSD 374 PP PP PL P + +P LP PP PG PPP P +P+F PP +G Sbjct: 287 QEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQAL- 345 Query: 375 SRGPPPTDPYGRPPPYDRGDYGPPG 399 P P P G P + +G PG Sbjct: 346 ---PAPPAPPGSQPFLQKKRHGRPG 367 Score = 75.1 bits (183), Expect = 2e-13 Identities = 71/210 (33%), Positives = 77/210 (36%), Gaps = 47/210 (22%) Query: 218 PGPAGPGGPP---PPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPP 274 PGP G P PP P PP PP P PP PP + + P LA P + PP Sbjct: 204 PGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLA-PLHLPPIPP 262 Query: 275 PPVLFPGQPFGQP-----PLGPL-----PPGPPPPVPGYG-------------------- 304 P L P P G P P P PP PPPP+P Y Sbjct: 263 PLPLLP--PCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSS 320 Query: 305 --PPPGPP--PPQQGPPPPPGPFP-PRPPGPLGPPLTLAPPPH-LPGPPPGA--PPPAPH 356 PPP PP P Q PP G P PP P G L H PG G PPPAP Sbjct: 321 ETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAP- 379 Query: 357 VNPAFFPPPTNSGMPTSDSRGPPPTDPYGR 386 PA P S + P P G+ Sbjct: 380 --PARSPTTELSSKSQQATAWTPTQQPGGQ 407 Score = 70.1 bits (170), Expect = 5e-12 Identities = 74/261 (28%), Positives = 81/261 (31%), Gaps = 100/261 (38%) Query: 223 PGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNR------------- 269 P PPPP P PP PPLG P PP P PP A P R Sbjct: 4 PPPPPPPLP----PPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRL 59 Query: 270 ------GDRPPPPV---------------------------LFPG-----QPFGQPPL-- 289 DR P + LF G +P GQ + Sbjct: 60 RKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAG 119 Query: 290 -----GPLPPGPPPPVPG---YGP--PPGPP---------------PPQQGPPPPPGPFP 324 GP P P +P GP PP P PP+ P PP P P Sbjct: 120 GKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTP 179 Query: 325 PRPPGPLGPPLTLAPP-----------------PHLPGPPPGAPPPAPHVNPAFFPPPTN 367 P PP PL PPL + P P + P P APPP P P PPP Sbjct: 180 PPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPP-TPPPLP 238 Query: 368 SGMPTSDSRGPPPTDPYGRPP 388 SD P P PP Sbjct: 239 PASVLSDKAVKPQLAPLHLPP 259 Score = 52.0 bits (123), Expect = 1e-06 Identities = 57/206 (27%), Positives = 60/206 (29%), Gaps = 61/206 (29%) Query: 198 PQGGRGRGRFPGAVPGGDRFPGPAGPGGPP--PPFPAGQT-------------------P 236 P G +G P P P P P PP PP P P Sbjct: 203 PPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPP 262 Query: 237 PRPPLGPPGPPG--------------PPGPPPPGQVLPP--------PLAGPP----NRG 270 P P L P G PG PP PPPP LPP L PP N Sbjct: 263 PLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPP---LPPYASCSPRASLPAPPLPGVNSS 319 Query: 271 DRPPPPVLFPGQPFGQPPLG------PLPPGPPPPVP-----GYGPPPGPPPPQQGPPPP 319 PPP+ F PP P PP PP P +G P PP P Sbjct: 320 SETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAP 379 Query: 320 PGPFPPRPPGPLGPPLTLAPPPHLPG 345 P P T P PG Sbjct: 380 PARSPTTELSSKSQQATAWTPTQQPG 405 Score = 47.4 bits (111), Expect = 3e-05 Identities = 58/212 (27%), Positives = 65/212 (30%), Gaps = 77/212 (36%) Query: 237 PRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPL------- 289 P PP PP PP PP PPP G PPP + PP D L P G+ L Sbjct: 2 PVPP--PPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSS---LRRADPKGRSALLADIQQG 56 Query: 290 ------GPLPPGPPPPV---PGYGPPPGPPPPQQGPPPPP-------GPFP--------- 324 + P + G G +G PP G FP Sbjct: 57 TRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRD 116 Query: 325 ----------------PRPP-----GPLGPPL---------------TLAPPPHLPGPPP 348 PR P GPL PP T P P++P PPP Sbjct: 117 VAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPP 176 Query: 349 GAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPP 380 PPP P PPP S P PP Sbjct: 177 PTPPPPPPP----LPPPLPSSSPIKTPLVSPP 204 Score = 40.4 bits (93), Expect = 0.004 Identities = 18/34 (52%), Positives = 19/34 (55%), Gaps = 4/34 (11%) Query: 292 LPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPP 325 +P PPPP P P PPPP PPPPP PP Sbjct: 1 MPVPPPPPPP----LPPPPPPLGAPPPPPPSAPP 30 Score = 33.5 bits (75), Expect = 0.52 Identities = 20/47 (42%), Positives = 22/47 (46%), Gaps = 3/47 (6%) Query: 341 PHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTS-DSRGPPPTDPYGR 386 P P PPP PPP P + PPP S P S D+ DP GR Sbjct: 2 PVPPPPPPPLPPPPPPLGAP--PPPPPSAPPVSTDTSSLRRADPKGR 46 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 104 bits (260), Expect = 2e-22 Identities = 97/283 (34%), Positives = 109/283 (38%), Gaps = 59/283 (20%) Query: 173 KTTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPG-----AVPGGDRFP--------- 218 K G G+G AGPPG P G +G FPG PG D P Sbjct: 929 KPGPKGNSGGDGPAGPPGERG----PNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGET 984 Query: 219 ---GPAGPGGPP----PPFPAGQTPPRPPLGPPGPPGPPGPP-------PPGQVLPPPLA 264 G GP GPP P P G+T P G PGPPGPPG G P A Sbjct: 985 GFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPA 1044 Query: 265 GPPNRGDRPPPPVLFPGQPFGQPPLGPL-------PPGPPPPV--PGYGPPPGPP----- 310 G P + D PP FPG P+G L PPGPP P PG P G Sbjct: 1045 GLPGK-DGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGI 1103 Query: 311 PPQQGPPPPPGPF----PPRPPGPLGPPLT--LAPPPHLPGPPPGAPPPAPHVNPAFFPP 364 P + GP PPGP P GP GP L P LPGP PP + Sbjct: 1104 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGE 1163 Query: 365 PTNSGMP-TSDSRGPP----PTDPYGRPPPYDR-GDYGPPGRE 401 P G +GPP P P G+P P G+ GP G++ Sbjct: 1164 PGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQ 1206 Score = 102 bits (253), Expect = 1e-21 Identities = 101/298 (33%), Positives = 114/298 (38%), Gaps = 74/298 (24%) Query: 178 GQMSGEGKAGPPG--GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP----PPFP 231 G EG GPPG GS P G G PG PG PGPAG G P P P Sbjct: 1072 GLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGR-PGPQGPPGPAGEKGAPGEKGPQGP 1130 Query: 232 AGQTPPRPPLGPPGPPGPPGPP----PPGQVLPPPLAGPP-NRGDRPPPPVLFPGQPFGQ 286 AG+ + P+G PGP GP GPP G++ P G ++G++ PP P P GQ Sbjct: 1131 AGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQ 1190 Query: 287 P-PLG----PLP------------------PGPPPPVPGYGPPPGPPPP--------QQG 315 P P G P P PGPP PV G PGPP Q G Sbjct: 1191 PGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPV-GLQGLPGPPGEKGETGDVGQMG 1249 Query: 316 PPPPPGPFPPR----PPGPLGPPLTLAPPPHL-----------PGPPPGAPPPAPHVN-- 358 PP PPGP P GP GPP + P + PG P PP P Sbjct: 1250 PPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERG 1309 Query: 359 -------PAFFPPPTNSGMPTSDS-RGPP-----PTDPYGRPPPYDRGDYGPPGREMD 403 PP G P D +G P P DP P G GPPG + D Sbjct: 1310 EKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGD 1367 Score = 100 bits (250), Expect = 3e-21 Identities = 109/318 (34%), Positives = 121/318 (38%), Gaps = 93/318 (29%) Query: 176 QSGQMSGEGKAGPPG-----------GSSRAAFPQGGRGR-GRFPGAVPGGDR-FPGPAG 222 Q G +G+ GPPG G S A G RG+ G F G R FPGP G Sbjct: 1166 QKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPG 1225 Query: 223 PGG----PPPPFPAGQTPPRPPLGPPGPPGPPGP-----------PP------------- 254 P G P PP G+T +GPPGPPGP GP PP Sbjct: 1226 PVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKG 1285 Query: 255 -PGQVLPPPL---AGPPN-RGDR-------------PPPPVLFPGQ--PFGQP-PLG--- 290 PG+ P L GPP +G+R PP P PG P G P P+G Sbjct: 1286 EPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPG 1345 Query: 291 -PLPPGPPPPVPGYGPP----PGPPPPQQGPPPPPG-PFPPRPPGPLGPPLTLAP----- 339 P PPG P P GPP P Q G P P G P P PPG GPP P Sbjct: 1346 DPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQG 1405 Query: 340 ------------PPHLPGP--PPGAP-PPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPY 384 PP GP P GAP P P P G+P S PP P Sbjct: 1406 EKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPP-GPM 1464 Query: 385 GRPP-PYDRGDYGPPGRE 401 G P P +GD GP G + Sbjct: 1465 GPPGLPGLKGDSGPKGEK 1482 Score = 100 bits (248), Expect = 5e-21 Identities = 90/254 (35%), Positives = 96/254 (37%), Gaps = 53/254 (20%) Query: 173 KTTQSGQMSGEGKAGP--PGGSSRAAFPQGGRGRGRFPGAV-----PGGDRFPGPAGPGG 225 +T GQM G GP P G+ A PQG G PGAV PG PG G GG Sbjct: 1241 ETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGG 1300 Query: 226 PPPPF----PAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPG 281 PP P G++ P GPPGP GPPG P +G P PV FPG Sbjct: 1301 PPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGP-------------KGS--PGPVGFPG 1345 Query: 282 QPFGQPPLGPLPPGPPPPVPGYGPPPGP----PPPQQGPPPPPG-PFPPRPPGPLGPPLT 336 P PPG P P GPP P Q G P P G P P PPG GPP Sbjct: 1346 DPG--------PPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGP 1397 Query: 337 LAPPPH-----------LPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYG 385 P L GPP P P P P G+P P P Sbjct: 1398 AGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGP 1457 Query: 386 RPPPYDRGDYGPPG 399 PP G GPPG Sbjct: 1458 DGPP---GPMGPPG 1468 Score = 97.1 bits (240), Expect = 4e-20 Identities = 96/283 (33%), Positives = 111/283 (39%), Gaps = 75/283 (26%) Query: 177 SGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG-PGGPPPPFPAGQT 235 +G+ G G G PG + P G RG R P + G PGP G GG P P G+ Sbjct: 894 NGEKGGRGTPGKPGPRGQRG-PTGPRGE-RGPRGITGK---PGPKGNSGGDGPAGPPGER 948 Query: 236 PPRPPLGPPGPPGPPGPP-PPGQVLPPPLAGPPNR----------GDRPPPPVLFPGQPF 284 P P GP G PGP GPP PPG+ L G P + G PP V+ P P Sbjct: 949 GPNGPQGPTGFPGPKGPPGPPGK---DGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPT 1005 Query: 285 GQP-PLG----PLPPGPP--PPVPGYG--------PPPGPPPPQQGPP---------PPP 320 G+ P+G P PPGPP +PG P P P + GPP P Sbjct: 1006 GETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLP 1065 Query: 321 GPF----------PPRPPGPLGPPLTLAP-----PPHLPGPPPGAPPPAPHVNPAFFPPP 365 GP PP PPGP G P P P +PG P PP P Sbjct: 1066 GPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPG---------PA 1116 Query: 366 TNSGMP-TSDSRGPPPTD----PYGRPPPYDRGDYGPPGREMD 403 G P +GP D P G P P G GPPG + D Sbjct: 1117 GEKGAPGEKGPQGPAGRDGLQGPVGLPGP--AGPVGPPGEDGD 1157 Score = 94.4 bits (233), Expect = 2e-19 Identities = 87/273 (31%), Positives = 99/273 (36%), Gaps = 73/273 (26%) Query: 176 QSGQMSGEGKAGPPG--GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP------ 227 + G+ G AGPPG G P+G G FPG PG PGPAG GPP Sbjct: 1310 EKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGD-PGPPGEPGPAGQDGPPGDKGDD 1368 Query: 228 -------PPFPAGQTPPRPPLGPPGPPGPPGPP----------------PPGQVLPPPLA 264 P P G+ P P G GPPGP GP PPG+ P Sbjct: 1369 GEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQ 1428 Query: 265 GPPNRGDRP-----PPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGP---------- 309 G P + P PV G P P GP P PP +PG GP Sbjct: 1429 GAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLI 1488 Query: 310 ----PPPQQGP------PPPPGPFPPR-------PPGPLGPPLTLAPPPHLPGPP----- 347 PP +QG P P G P+ P GP+GPP PP LPGPP Sbjct: 1489 GLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPP----GPPGLPGPPGPKGA 1544 Query: 348 PGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPP 380 G+ P A P P P + P P Sbjct: 1545 KGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLP 1577 Score = 90.9 bits (224), Expect = 3e-18 Identities = 100/320 (31%), Positives = 108/320 (33%), Gaps = 109/320 (34%) Query: 184 GKAGPPG-----GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP----------- 227 G GPPG G+ PQG GR G V PGPAGP GPP Sbjct: 1108 GPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVG----LPGPAGPVGPPGEDGDKGEIGE 1163 Query: 228 -----------PPFPAGQTPPRPPLGPPGPP---GPPG-------------------PPP 254 P G T P+ P+G PGP G PG P P Sbjct: 1164 PGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGP 1223 Query: 255 PGQVLPPPLAGPPNR-------GDRPPPPVLFPGQPFGQPPLGPLPPGPP---------- 297 PG V L GPP G PP P P G P P GPP Sbjct: 1224 PGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADG-PQGPPGGIGNPGAVG 1282 Query: 298 ----------PPVPGYGPPPGP-----------PPPQQGPPPPPGP----FPPRPPGPLG 332 P +PG G PPGP P GPP P GP P PGP+G Sbjct: 1283 EKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVG 1342 Query: 333 PPLTLAPPPHLPGP-----PPGAPPPAPHVNPAFFPPPTNSGMPTS--DSRGPP-PTDPY 384 P PP PGP PPG P PT P+ RGPP P P Sbjct: 1343 FPGDPGPPGE-PGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPE 1401 Query: 385 GRP----PPYDRGDYGPPGR 400 GR + G GPPG+ Sbjct: 1402 GRQGEKGAKGEAGLEGPPGK 1421 Score = 88.6 bits (218), Expect = 1e-17 Identities = 92/279 (32%), Positives = 107/279 (38%), Gaps = 61/279 (21%) Query: 164 LSQFEMQSRKTTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGP 223 +S E Q++ Q +++ G AGP G + R P G G G G PG GP Sbjct: 539 VSAQESQAQAILQQARLALRGPAGPMGLTGRPG-PVGPPGSGGLKGE-------PGDVGP 590 Query: 224 GGPP----PPFPAGQTPPRPPLGPPGPPGPPGPPPP----------------GQVLPPPL 263 GP PP PAG+ R G G G PG P G P Sbjct: 591 QGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGP 650 Query: 264 AGPPN-------RGDRPPP-PVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQ-- 313 +GPP RGD P PG+P + LGP P PP PG G P P+ Sbjct: 651 SGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGN 710 Query: 314 ---QGPPPPPGPFP-------PRPPGPLGPPLTLAP--PPHLPGPPPGAPPPAPHVNPAF 361 QG P PPG P P G +GPP P P LPG P PP +P Sbjct: 711 VGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPG---HPGK 767 Query: 362 FPPPTNSGMPTSDSRGPP-PTDPYGRPPPYDRGDYGPPG 399 PP G +GPP P P G P P RG G G Sbjct: 768 EGPPGEKG-----GQGPPGPQGPIGYPGP--RGVKGADG 799 Score = 85.5 bits (210), Expect = 1e-16 Identities = 94/291 (32%), Positives = 107/291 (36%), Gaps = 69/291 (23%) Query: 176 QSGQMSGEGKAGPPGGSSRAAFP--------QGGRGRGRFPGAVPGGDRFPGPAG-PGGP 226 + G G GPPG + P QG +G FPG PG + G G PG P Sbjct: 848 RGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPG-FPGANGEKGGRGTPGKP 906 Query: 227 PPPFPAGQTPPRPPLGPPGPPGPPGPP----------PPGQVLPPPLAGP-----PNRGD 271 P G T PR GP G G PGP PPG+ P GP P Sbjct: 907 GPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPP 966 Query: 272 RPPPPVLFPGQPFGQPPLG----PLPPGPPPPVPGYGPP-----------PGP--PPPQQ 314 PP PG P + G PPGPP V GP PGP PP +Q Sbjct: 967 GPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQ 1026 Query: 315 GPPPPPG-------PFPPRPPGPLGPPLTLAPPPH--LPGP-----------PPGAPPPA 354 G P G P P PG GPP P LPGP PPG PP Sbjct: 1027 GLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPG--PPG 1084 Query: 355 PHVNPAFFPPPTNSGMPTSDSRGPPPTDPYG----RPPPYDRGDYGPPGRE 401 P +P P +G P P P P G + P ++G GP GR+ Sbjct: 1085 PAGSPGERGPAGAAG-PIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD 1134 Score = 82.0 bits (201), Expect = 1e-15 Identities = 75/205 (36%), Positives = 87/205 (42%), Gaps = 47/205 (22%) Query: 174 TTQSGQMSGEGKAGPPG--GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAG-PGGPPP-- 228 T + G GK GPPG G +G +G G PG GP G PG P P Sbjct: 1380 TGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGP-PGKTGPIGPQGAPGKPGPDG 1438 Query: 229 ----PFPAGQT--PPRP-PLGPPGPPGPPGPP-------PPGQVLPPPLAG---PPN--- 268 P P G+ P P P GPPGP GPPG P P G+ P L G PP Sbjct: 1439 LRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQG 1498 Query: 269 -RGDRPPPPVLFPGQPFGQP----PLGPLPPGPPPPVPGYGPPPGP-----------PPP 312 +GDR P P G+ P GP+ P PP +PG PPGP P Sbjct: 1499 EKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPG---PPGPKGAKGSSGPTGPKG 1555 Query: 313 QQGPPPPPGPFPPRPPGPLGPPLTL 337 + G P PPGP P PPG + PL + Sbjct: 1556 EAGHPGPPGP--PGPPGEVIQPLPI 1578 Score = 77.8 bits (190), Expect = 2e-14 Identities = 92/300 (30%), Positives = 104/300 (34%), Gaps = 80/300 (26%) Query: 178 GQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPG-----AVPGGDRFPGPAGPGGPP----- 227 G+ G+G GP G P+G +G G G D FPG G G Sbjct: 772 GEKGGQGPPGPQGPIGYPG-PRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGE 830 Query: 228 --PPFPAGQTPPRPPLGPPGPPGPPGP--PP--PGQVLPPPLAGPPNRGDRPPPPVLFPG 281 PP P G+ P P G GP G PGP PP G++ P L G P R P + FPG Sbjct: 831 IGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGR-QGPKGSIGFPG 889 Query: 282 QPFGQPPLGPL-PPGPPPPVPGYGP--------------PPGP-----------PPPQQG 315 P G PG P P GP PGP PP ++G Sbjct: 890 FPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERG 949 Query: 316 PPPPPGPFP-PRPPGPLGPPLTLAPPPH--------------LPGPPPGAPPPAP----- 355 P P GP P P GP GPP P H PGPP P P Sbjct: 950 PNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETG 1009 Query: 356 ----HVNPAFFPPPTNSGMP-------TSDSRGPPPTDPYGRPP-----PYDRGDYGPPG 399 +P PP G+P T GP PP P DRG GP G Sbjct: 1010 PMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVG 1069 Score = 71.6 bits (174), Expect = 2e-12 Identities = 94/318 (29%), Positives = 103/318 (32%), Gaps = 101/318 (31%) Query: 178 GQMSGEGKAGPPG-----------GSSRAAFPQGGRGRGRFPG--AVPGGDRFPGPAGPG 224 G + +G+ GPPG G A P G +G PG +PG D PG G Sbjct: 709 GNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKE 768 Query: 225 GPP-------PPFPAGQ---------------------------------------TPPR 238 GPP PP P G R Sbjct: 769 GPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDR 828 Query: 239 PPLGPPGPPGPPGPPPP----GQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLG---- 290 +GPPGP G GP P G P GPP + P L PG P Q P G Sbjct: 829 GEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGL-PGYPGRQGPKGSIGF 887 Query: 291 PLPPGPPPPVPGYGPPPGP-PPPQQGPPPPPGPFPPR-------------PPGPLGPPLT 336 P PG G G P P P Q+GP P G PR GP GPP Sbjct: 888 PGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGE 947 Query: 337 LAP-----PPHLPGP--PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPP-------PTD 382 P P PGP PPG PP P P GPP P Sbjct: 948 RGPNGPQGPTGFPGPKGPPG--PPGKDGLPGH--PGQRGETGFQGKTGPPGPPGVVGPQG 1003 Query: 383 PYGRPPPY-DRGDYGPPG 399 P G P +RG GPPG Sbjct: 1004 PTGETGPMGERGHPGPPG 1021 Score = 61.2 bits (147), Expect = 2e-09 Identities = 84/312 (26%), Positives = 96/312 (30%), Gaps = 118/312 (37%) Query: 198 PQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPG------ 251 P+G +G+ P + G GP GP GP AG P +GP G G PG Sbjct: 448 PRGEKGQKGEPAIIEPGMLIEGPPGPEGP-----AGLPGPPGTMGPTGQVGDPGERGPPG 502 Query: 252 ----------PPPPGQVLPPPL------------------------------------AG 265 P PPG +L P AG Sbjct: 503 RPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAG 562 Query: 266 PPNRGDR-----PPPPVLFPGQPFGQPPLGPL----PPGPPPP--------------VPG 302 P R PP G+P P GP PPGP +PG Sbjct: 563 PMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPG 622 Query: 303 YGPPPGP-----------------PPPQQGPPPPPGP----------FPPRPPGPLGPPL 335 P G P GPP PPG P PG GP Sbjct: 623 QTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRG 682 Query: 336 TLAP--PPHLPGPP-----PGAPPPAPHVNPAFFP-PPTNSGMPTSDSRGPPPTDPYGRP 387 L P PP PGPP G P P +V P P PP G P + P P G Sbjct: 683 LLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGL-PGPQGAIG-- 739 Query: 388 PPYDRGDYGPPG 399 PP ++G G PG Sbjct: 740 PPGEKGPLGKPG 751 Score = 48.5 bits (114), Expect = 2e-05 Identities = 52/168 (30%), Positives = 62/168 (36%), Gaps = 13/168 (7%) Query: 236 PPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPN-RGDRPPPPVLFPGQPFGQPPLGPLPP 294 P P P GP G P + + GP +G + P ++ PG PP GP P Sbjct: 419 PYYDPTSSPSEIGP-GMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPP-GPEGP 476 Query: 295 GPPPPVPGYGPPPGP--PPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPP 352 P PG P G P ++GPP PG P G GPP T+ P G A Sbjct: 477 AGLPGPPGTMGPTGQVGDPGERGPPGRPGL--PGADGLPGPPGTMLMLPFRFGGGGDAGS 534 Query: 353 PAPHVNPAFFPPPTNSGMPTSDSRGPP-PTDPYGRPPPYDRGDYGPPG 399 P V+ RGP P GRP G GPPG Sbjct: 535 KGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRP-----GPVGPPG 577 Score = 47.4 bits (111), Expect = 3e-05 Identities = 32/88 (36%), Positives = 38/88 (43%), Gaps = 10/88 (11%) Query: 176 QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAV--PGGDRFPGPAGP----GGPPPP 229 + G+ G GP G S P+G +G G + PG PGP GP G P Sbjct: 1496 EQGEKGDRGLPGPQGSSG----PKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPT 1551 Query: 230 FPAGQTPPRPPLGPPGPPGPPGPPPPGQ 257 P G+ P GPPGPPG P P Q Sbjct: 1552 GPKGEAGHPGPPGPPGPPGEVIQPLPIQ 1579 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 103 bits (256), Expect = 5e-22 Identities = 94/253 (37%), Positives = 100/253 (39%), Gaps = 43/253 (16%) Query: 184 GKAGPPG--GSSRAAFPQGGRGRGRFPG--AVPG---GDRFPGPAG----PGGPPPPFPA 232 G AGPPG G AA P G G PG +PG G PGP G PGGP Sbjct: 696 GGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVP 755 Query: 233 GQTPPRPPLGPPGPPGPPGPP--------PPGQVLPPPLAGPPNRGDR-PPPPVLFPGQP 283 G+ PR P GP GPPGP G P P + P P RG+ PP P FPG P Sbjct: 756 GKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAP 815 Query: 284 FGQPPLGPLPPGPPPPVPGYGPPPG--PPPPQQGPPPPPGP-------FPPRPPGPLGPP 334 G P G G PPG PP GP PPGP P PG G P Sbjct: 816 GQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFP 875 Query: 335 LTLAPPPHLPGPP-----PGAPPPAPHVNPAFFPPP---TNSGMPTSDSRGPPPTDPYGR 386 LPGPP PG PP P +P PP N+G P S P D Sbjct: 876 GARG----LPGPPGSNGNPG--PPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQP 929 Query: 387 PPPYDRGDYGPPG 399 G GPPG Sbjct: 930 GEKGSPGAQGPPG 942 Score = 89.7 bits (221), Expect = 6e-18 Identities = 89/257 (34%), Positives = 99/257 (38%), Gaps = 48/257 (18%) Query: 178 GQMSGEGKAGPPG--GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQT 235 G +GK GPPG G S P G G P PG FPGP G G P Sbjct: 543 GGPGSDGKPGPPGSQGESGRPGPPGPSG----PRGQPGVMGFPGPKGNDGAPGKNGERGG 598 Query: 236 PPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDR-PPPPVLFPGQP-FGQPPLGPLP 293 P P GP GPPG G P Q P P ++GD PP P G P G PP Sbjct: 599 PGGP--GPQGPPGKNGETGP-QGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGK 655 Query: 294 PGPPPPVPGYGPPPGP-------PPPQQGPP------------PPPGP-------FPPRP 327 PG P P G P P P ++GPP PPGP PP P Sbjct: 656 PGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGP 715 Query: 328 PGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGP-PPTDPYGR 386 PG G P +PG G P P + P G+P D GP PT P G Sbjct: 716 PGAAGTPGLQG----MPGERGGLGSPGPKGDKGEPGGPGADGVPGKD--GPRGPTGPIGP 769 Query: 387 P----PPYDRGDYGPPG 399 P P D+G+ G PG Sbjct: 770 PGPAGQPGDKGEGGAPG 786 Score = 88.6 bits (218), Expect = 1e-17 Identities = 93/278 (33%), Positives = 102/278 (36%), Gaps = 58/278 (20%) Query: 176 QSGQMSGEGKAGPPGGSSRAA--FPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAG 233 + G+ G AGPPGGS A PQG +G PG PG FPG G GPP G Sbjct: 832 EKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGG-PGAAGFPGARGLPGPPGS--NG 888 Query: 234 QTPPRPPLGPPGPPGPPGPP-PPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPL 292 P P G PG GPPGP G P ++GP +GD P G P Q P P Sbjct: 889 NPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGP--KGDAGQPGE--KGSPGAQGP--PG 942 Query: 293 PPGP--------------PPPVPGYGPPPGPP--PPQQGPPPPPGPFPPR-PPGPLGPP- 334 PGP PP +PG PGP + G P G R PPGP G P Sbjct: 943 APGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPG 1002 Query: 335 -LTLAPPPHLPGPP-----------------------PGAPPPAPHVNPAFFPPPTNSGM 370 A P G P PGAP H P P P Sbjct: 1003 LAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGP---PGPVGPAG 1059 Query: 371 PTSDSRGPPPTDPYGRP-PPYDRGDYGPPGREMDTART 407 + D P P G P P RG GP G D T Sbjct: 1060 KSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGET 1097 Score = 87.4 bits (215), Expect = 3e-17 Identities = 91/274 (33%), Positives = 108/274 (39%), Gaps = 50/274 (18%) Query: 176 QSGQMSGEGKAGPPGGSSRAAFP-----QGGRGRGRFPG-----AVPG--GDR----FPG 219 + G+ +G+ GP G A P +G G+ PG +PG G+R F G Sbjct: 433 EPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRG 492 Query: 220 PAGPGG-PPPPFPAGQTPPRPPLGPPGPPGPPG----PPPPGQVLPPPLAGPPNRGDRPP 274 PAGP G P PAG+ P GP G G PG P PG P G P +P Sbjct: 493 PAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPG 552 Query: 275 PPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPP---------------PGPPPPQQGPPPP 319 PP G+ P GP P P V G+ P PG P PQ GPP Sbjct: 553 PPGS-QGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQ-GPPGK 610 Query: 320 PGPFPPR-PPGPLGP----PLTLAPPPH-LPGPPPGAPPPAPHVNPAFFPPPTNSGMP-- 371 G P+ PPGP GP T P P L G P PP + P P ++G P Sbjct: 611 NGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGA 670 Query: 372 ---TSDSRGPPPTDPYG-RPPPYDRGDYGPPGRE 401 D+ P P G P RG GPPG E Sbjct: 671 PGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPE 704 Score = 84.0 bits (206), Expect = 3e-16 Identities = 80/232 (34%), Positives = 89/232 (38%), Gaps = 36/232 (15%) Query: 178 GQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGP----AGPGGPPPPFPAG 233 G G+ GPPG S P+G G FPG G D PG GPGGP P P G Sbjct: 555 GSQGESGRPGPPGPSG----PRGQPGVMGFPGP-KGNDGAPGKNGERGGPGGPGPQGPPG 609 Query: 234 QTPPRPPLGPPGPPGPPGPP----PPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPL 289 + P GPPGP GP G PPG P L G P G PP PG+P Sbjct: 610 KNGETGPQGPPGPTGPGGDKGDTGPPG---PQGLQGLPGTGG-PPGENGKPGEP------ 659 Query: 290 GPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPG 349 GP P PG G P ++GPP G PG G A PP G Sbjct: 660 GPKGDAGAPGAPG-GKGDAGAPGERGPPGLAGA-----PGLRGG----AGPPGPEGGKGA 709 Query: 350 APPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGRE 401 A PP P P P GMP P + P G G PG++ Sbjct: 710 AGPPGP---PGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKD 758 Score = 80.5 bits (197), Expect = 4e-15 Identities = 65/183 (35%), Positives = 73/183 (39%), Gaps = 23/183 (12%) Query: 184 GKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPF-PAGQTPPRPPLG 242 G+ G PGG +G RG PGA PG PGP GP GP G++ P P G Sbjct: 1023 GRDGSPGG-------KGDRGENGSPGA-PGAPGHPGPPGPVGPAGKSGDRGESGPAGPAG 1074 Query: 243 PPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVL----FPGQPFGQPPLGPLPP---- 294 PGP G G P P P G+R + FPG P GP Sbjct: 1075 APGPAGSRGAPGP----QGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAI 1130 Query: 295 GPPPPVPGYGPP-PGPPPPQQGPPPPPGPF-PPRPPGPLGPPLTLAPPPHLPGPPPGAPP 352 G P P GP P PP + G PGP PP P G G + P H P P PP Sbjct: 1131 GSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPP 1190 Query: 353 PAP 355 AP Sbjct: 1191 GAP 1193 Score = 71.6 bits (174), Expect = 2e-12 Identities = 82/283 (28%), Positives = 97/283 (34%), Gaps = 64/283 (22%) Query: 178 GQMSGEGKAGPPGGSSRAAFP--------------QGGRGRGRFPG-----AVPGGDRFP 218 G+ G GPPG A P G +G PG +PG + P Sbjct: 237 GRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAP 296 Query: 219 GPAGPGGPP-----PPFPA-----GQTPPRPPLGPPGPPGPPG-------PPPPGQVLPP 261 GP GP G P P P G R G PGPPGPPG P G+V P Sbjct: 297 GPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPA 356 Query: 262 PLAG----PPNRGDR----------PPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPP 307 G P RG+ PP P G P G+ +GP P + G PP Sbjct: 357 GSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPP 416 Query: 308 GPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAP--PPHLPGPPPGAPPPAPHVNPAFFPPP 365 GP P G P G G P +PG P +P P Sbjct: 417 GPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPG---EP 473 Query: 366 TNSGMP-TSDSRGPP----PTDPYGRP----PPYDRGDYGPPG 399 +G+P + RG P P P G P P +RG GP G Sbjct: 474 GANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAG 516 Score = 71.2 bits (173), Expect = 2e-12 Identities = 98/314 (31%), Positives = 111/314 (35%), Gaps = 95/314 (30%) Query: 178 GQMSGEGKAGPPG------GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPP-- 229 GQ G GPPG + PQ + AV G +PGPAGP GPP P Sbjct: 127 GQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPG 186 Query: 230 ---------FPAGQTPPRPP-----LGPPGPPGPPGPP-PPGQVLPPPLAGPPNRGDRPP 274 P Q PP P GPPGPPG GP P G+ G P P Sbjct: 187 TSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPG 246 Query: 275 PPVL--------FPGQ--------------PFGQPPL---GPLP-----PGP--PPPVPG 302 PP + FPG G P L LP PGP P PG Sbjct: 247 PPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPG 306 Query: 303 YGPPPGPP--------------PPQQGPPPPPGP--FPPRP-----PGPLGPPLTLAPPP 341 PG P Q GPP PPG FP P GP G P + P Sbjct: 307 ERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPG 366 Query: 342 HL--PGP--------PPGAPPPAPHVNPAFFPPPTNSGMPTS----DSRGPP-PTDPYGR 386 PGP PPG PP + +P +G+P + +RGPP P G Sbjct: 367 QRGEPGPQGHAGAQGPPG--PPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGA 424 Query: 387 PPPYDRGDYGPPGR 400 P RG G PG+ Sbjct: 425 PGL--RGGAGEPGK 436 Score = 70.5 bits (171), Expect = 4e-12 Identities = 72/223 (32%), Positives = 80/223 (35%), Gaps = 56/223 (25%) Query: 218 PGPAGPGGP-----PPPFPAGQTPP--RPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRG 270 P P P G P P A PP + P GP G PGPPG PG+ P + G P Sbjct: 75 PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPG--IPGRNGDPGIPGQPGSP 132 Query: 271 DRPPPPVLFPGQPFGQPPLGPL-----------------------PPGPPPPVPGYGPPP 307 P PP + P G P PPGPP P PG P Sbjct: 133 GSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGP-PGTSGHP 191 Query: 308 GPP--PPQQGPPPPPGPF----PPRPPGPLGP--PLTLAPPPHLPGPP--PGAPPPAPHV 357 G P P QGPP PG PP PPG +GP P PG P G P P Sbjct: 192 GSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIK 251 Query: 358 NPAFFPP-PTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPG 399 PA P P G D R ++G+ G PG Sbjct: 252 GPAGIPGFPGMKGHRGFDGRNG------------EKGETGAPG 282 Score = 68.2 bits (165), Expect = 2e-11 Identities = 61/147 (41%), Positives = 66/147 (44%), Gaps = 28/147 (19%) Query: 176 QSGQMSGEGKAGP-----PGGSSRAAFPQGGRG-RG----RFPGAVPGGDRFPGPAGPGG 225 +SG G AGP P GS A PQG RG +G R + G FPG PG Sbjct: 1060 KSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPG--NPGA 1117 Query: 226 PPPPFPAGQTPPRPPLGPPGPPGPPGP--PP--------PGQVLPPPLAGPPNRGDRPPP 275 P P PAGQ GP GP GP GP PP PG + PP G NRG+R Sbjct: 1118 PGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRG--NRGERGSE 1175 Query: 276 PVLFPGQPFGQPPLGPLPPGPPPPVPG 302 PG P GQP P PPG P P G Sbjct: 1176 G--SPGHP-GQPG-PPGPPGAPGPCCG 1198 Score = 35.4 bits (80), Expect = 0.14 Identities = 22/58 (37%), Positives = 25/58 (43%), Gaps = 8/58 (13%) Query: 176 QSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAG 233 + G G GPPG P+G RG G+ PG PGP GP G P P G Sbjct: 1150 KDGTSGHPGPIGPPG-------PRGNRGERGSEGS-PGHPGQPGPPGPPGAPGPCCGG 1199 >gi|146134388 YLP motif containing 1 [Homo sapiens] Length = 2146 Score = 103 bits (256), Expect = 5e-22 Identities = 89/242 (36%), Positives = 103/242 (42%), Gaps = 39/242 (16%) Query: 226 PPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAG---PPNRGDRPPPPVLFPGQ 282 PPP P Q PP P PP P PP PPP V+PP L PP PPPV+ P Sbjct: 517 PPPFVPYSQMPPPLPTMPP-PVLPPSLPPP--VMPPALPATVPPPGM----PPPVMPPSL 569 Query: 283 PFGQPP---------LGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGP 333 P PP GP P PPP + GPPP PPP PP P PL P Sbjct: 570 PTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPP------PVMPL-P 622 Query: 334 PLTLAPPPHLPG-PPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDR 392 PL+ A PP PG PPPG P P A PP +S + S+ P P P P Sbjct: 623 PLSSATPP--PGIPPPGVPQGIPPQLTAAPVPPASS---SQSSQVPEKPRPALLPTPVSF 677 Query: 393 GDYGPPGREMDTARTPLSEAEFEEIMNRNRAISSSAI--SRAVSDASAGDYGSAIETLVT 450 G P T PL A E +N +S SA+ S SD G+ +A +T Sbjct: 678 GSAPP-----TTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPIT 732 Query: 451 AI 452 A+ Sbjct: 733 AV 734 Score = 79.3 bits (194), Expect = 8e-15 Identities = 59/192 (30%), Positives = 70/192 (36%), Gaps = 16/192 (8%) Query: 226 PPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVL----PPPLAGPPNRGDRPPPPVLFPG 281 PPPP P P G PP PP PPPPG L R PP L P Sbjct: 82 PPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPM 141 Query: 282 QPFGQPPLGPLPPGP-PPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLT---L 337 + P P+PPG PP Y PPP PPP P PP P P P + L Sbjct: 142 ELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYL 201 Query: 338 APPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGP 397 AP P + H P++ P+ S+G + PPP P Sbjct: 202 APTPSYSSSSSSSQSYLSHSQSYL---PSSQASPSRPSQGHSKSQLLAPPPP-----SAP 253 Query: 398 PGREMDTARTPL 409 PG + + PL Sbjct: 254 PGNKTTVQQEPL 265 Score = 70.9 bits (172), Expect = 3e-12 Identities = 85/300 (28%), Positives = 115/300 (38%), Gaps = 57/300 (19%) Query: 267 PNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPR 326 P D PP +P + P PPG P P G PPG PP R Sbjct: 1483 PQMADHLPPQESRLQNTSSRPGMYP-PPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTR 1541 Query: 327 PPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGM-PTSDSRG-------- 377 PP P+ PP PPP LP PPP P V + + G+ T+D +G Sbjct: 1542 PPVPIPPP---PPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSE 1598 Query: 378 --PPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAEFEEIMNRNRAISSSAISRAVSD 435 P+ P PPP PPG + P+S+ + + V Sbjct: 1599 TAAIPSAPVLPPPPV-HSSIPPPG-PVPMGMPPMSK--------------PPPVQQTV-- 1640 Query: 436 ASAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISSLQDCLHGIESKSYGSGSRRERSR 495 DYG + IS K ++ +R + L + E++ G R +R R Sbjct: 1641 ----DYGHGRD-----ISTNKVEQIPYGERITLRPDPLPE-RSTFETEHAGQRDRYDRER 1690 Query: 496 ERDHSRSREKSRRHKSRSRDRHDDYYRERSRERERHRDRDRDR---DRERDR-EREYRHR 551 +R+ R+ S H D+ R+RE HRDRDRDR D +RDR +RE R R Sbjct: 1691 DREPYFDRQ------SNVIADHRDF----KRDRETHRDRDRDRGVIDYDRDRFDRERRPR 1740 Score = 70.1 bits (170), Expect = 5e-12 Identities = 65/207 (31%), Positives = 74/207 (35%), Gaps = 33/207 (15%) Query: 247 PGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPG-----------------------QP 283 P PP PPPP LP GP P G Q Sbjct: 15 PPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQC 74 Query: 284 FGQPPLGPLPPGPPPPV---PGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPP 340 QP P PP PPPPV GYG PPPP PPPPGP L Sbjct: 75 VLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPM---PPPPGPALSYQKQQQYKHQML--- 128 Query: 341 PHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGR 400 H PPG P P P P S MP S S PPP P PP Y PP Sbjct: 129 HHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPA- 187 Query: 401 EMDTARTPLSEAEFEEIMNRNRAISSS 427 + +++P S++ + + + SSS Sbjct: 188 QPSPSQSPPSQSYLAPTPSYSSSSSSS 214 Score = 57.8 bits (138), Expect = 3e-08 Identities = 45/127 (35%), Positives = 48/127 (37%), Gaps = 17/127 (13%) Query: 223 PGGPPPPFPAGQTPPRPP-----LGPPGPPGPPG----PPPPGQVLPPPLAGPPNRGDRP 273 PG PP AG P PP GPP PP PPP LPP + P Sbjct: 576 PGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSA------TP 629 Query: 274 PPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGP 333 PP + PG P G PP L P PP P P+ P P F PP P Sbjct: 630 PPGIPPPGVPQGIPP--QLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHP 687 Query: 334 PLTLAPP 340 PL A P Sbjct: 688 PLQSAGP 694 Score = 55.5 bits (132), Expect = 1e-07 Identities = 47/156 (30%), Positives = 52/156 (33%), Gaps = 46/156 (29%) Query: 229 PFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAG-PPNRGDRPPPPVLFPGQPFGQP 287 P A PP+ P PPPG PPP G PP RP P P +P Sbjct: 1483 PQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRP 1542 Query: 288 PLGPLPPGPPPPVPGYGPPPGPPPPQ-----------------------QG--------- 315 P+ PP PPPP+P PPP PQ QG Sbjct: 1543 PVPIPPPPPPPPLP---PPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSET 1599 Query: 316 ----------PPPPPGPFPPRPPGPLGPPLTLAPPP 341 PPP PP P P+G P PPP Sbjct: 1600 AAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPP 1635 Score = 52.0 bits (123), Expect = 1e-06 Identities = 52/177 (29%), Positives = 62/177 (35%), Gaps = 36/177 (20%) Query: 161 KQFLSQFEMQSRKTTQSGQMSGEGKAG---PPGGSSRAAFPQGGRGRGRFPGAVPGGDRF 217 K F S+ +M Q ++ PP GS R P G + PG++ Sbjct: 1477 KDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMG-----KPPGSI------ 1525 Query: 218 PGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPV 277 P PP T P P+ PP PP P PPPP + P A R D Sbjct: 1526 ---VRPSAPPARSSVPVTRPPVPIPPPPPPPPL-PPPPPVIKPQTSAVEQERWDEDSFYG 1581 Query: 278 L------------FPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPP---PQQGPPPP 319 L F + P P PPPPV PPPGP P P PPP Sbjct: 1582 LWDTNDEQGLNSEFKSETAAIP---SAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPP 1635 Score = 49.7 bits (117), Expect = 7e-06 Identities = 40/134 (29%), Positives = 44/134 (32%), Gaps = 41/134 (30%) Query: 208 PGAVPGGDRFPGPAGPGGPPPPFPAGQTPP--------RPPLG-PPGPPGPPGPPPPGQV 258 PG P + P G PP PP RPP+ PP PP PP PPPP + Sbjct: 1503 PGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVI 1562 Query: 259 LPPPLAGPPNRGDR--------------------------------PPPPVLFPGQPFGQ 286 P A R D PPPPV P G Sbjct: 1563 KPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGP 1622 Query: 287 PPLGPLPPGPPPPV 300 P+G P PPPV Sbjct: 1623 VPMGMPPMSKPPPV 1636 Score = 39.7 bits (91), Expect = 0.007 Identities = 68/295 (23%), Positives = 76/295 (25%), Gaps = 139/295 (47%) Query: 218 PGPAGPGG-------PPPPFPAGQTPPRPPL------------------GPPG------- 245 P P PGG PPPP P PP P L GPPG Sbjct: 88 PPPVMPGGGYGDWQPPPPPMPP---PPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELE 144 Query: 246 -----PPGPPGP--PPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQ--PP----LGPL 292 PP PPG PP +PPP P P L P QP PP L P Sbjct: 145 SPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPT 204 Query: 293 PP------------------------GPPPPVPGYG-------PPPGPPP---------- 311 P P P G+ PPP PP Sbjct: 205 PSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEP 264 Query: 312 ------------PQQGPPPPPGPFPPRP-------------------------------- 327 Q P P P P+ Sbjct: 265 LESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAK 324 Query: 328 --PGPLGPPLTLAPPPHLPGPP----PGAPPPAPHVNPAFFPPPTNSGMPTSDSR 376 P P+ +T+ +P P P PPP V P P S P D+R Sbjct: 325 DTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDAR 379 Score = 35.4 bits (80), Expect = 0.14 Identities = 21/65 (32%), Positives = 27/65 (41%), Gaps = 4/65 (6%) Query: 329 GPLGPPLTLAPPPHLPGPPPGAPPPA--PHVNPAFFPPPTNSGMPTSDSRGP--PPTDPY 384 G + P P +P P P PPP P + P PP + +P P PP+ P Sbjct: 512 GNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPT 571 Query: 385 GRPPP 389 PPP Sbjct: 572 SVPPP 576 Score = 30.8 bits (68), Expect = 3.4 Identities = 60/272 (22%), Positives = 81/272 (29%), Gaps = 61/272 (22%) Query: 218 PGPAGPGGPPPPFPAGQTPP-------------RPPLGPPGPPGPPGPPPPGQVLPPPLA 264 P P P G PP A PP RP L P P G PP PP + Sbjct: 634 PPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPT--PVSFGSAPPTTYHPPLQS 691 Query: 265 GPPNRGDRPPPPVLFPGQPFGQ------------PPLGPLPPGPPPPVPGYGPPPGPPPP 312 P+ P+ P+ P P+ PV G P PP Sbjct: 692 AGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRS 751 Query: 313 Q--QGPPPPPGPFP------------PRPPGP-LGPPLTLAPPPHLPGPP---------- 347 + P P P PRP GP P P G P Sbjct: 752 SYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEGHPAEGTKSKWGM 811 Query: 348 -PGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTAR 406 P P ++ P+ P SG +GP P +G+ P + + Sbjct: 812 IPRGPASQFYITPSTSLSPRQSG---PQWKGPKPA--FGQQHQQQPKSQAEP---LSGNK 863 Query: 407 TPLSEAEFEEIMNRNRAISSSAISRAVSDASA 438 PL++ + N ++ +I+ V D A Sbjct: 864 EPLADTSSNQQKNFKMQSAAFSIAADVKDVKA 895 Score = 30.0 bits (66), Expect = 5.7 Identities = 16/40 (40%), Positives = 19/40 (47%), Gaps = 2/40 (5%) Query: 220 PAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVL 259 P+ P PPPP + PP P P G P PPP Q + Sbjct: 1603 PSAPVLPPPPVHSSIPPPGPV--PMGMPPMSKPPPVQQTV 1640 Score = 29.6 bits (65), Expect = 7.5 Identities = 18/58 (31%), Positives = 23/58 (39%), Gaps = 1/58 (1%) Query: 217 FPGPAGPGGPPPPFPAGQTP-PRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRP 273 + GP+ GG +P + P P P L PP P P + PP R RP Sbjct: 1775 YEGPSMFGGERRTYPEERMPLPAPSLSHQPPPAPRVEKKPESKNVDDILKPPGRESRP 1832 Score = 29.3 bits (64), Expect = 9.8 Identities = 16/49 (32%), Positives = 26/49 (53%), Gaps = 1/49 (2%) Query: 497 RDHSRSREKSRRHKSRSRDRH-DDYYRERSRERERHRDRDRDRDRERDR 544 R+ S SR H R DD+ R++ + + +R+ +RD DR+ DR Sbjct: 1244 REDRFSAPPSRSHDGDRRGPWWDDWERDQDMDEDYNREMERDMDRDVDR 1292 >gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 102 bits (255), Expect = 7e-22 Identities = 105/297 (35%), Positives = 120/297 (40%), Gaps = 77/297 (25%) Query: 176 QSGQMSGEGKAGPPG--------GSSRAAF--PQGGRGRGRFPGAV-PGGDRFP-GPAGP 223 Q G G+G+ G PG G + F P+G RG G PGA+ P G++ P G G Sbjct: 326 QPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGI 385 Query: 224 GGPP--PPFPAGQTPPRPP--------------LGPPGPPGPPGPP-------------- 253 GGPP P P P PP +GP GPPGP G P Sbjct: 386 GGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGE 445 Query: 254 --PPG-QVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLG-PLPPGP-----PPPVPGYG 304 PPG + LP P+ G + P + PG P P G P PG PP +PG G Sbjct: 446 VGPPGMRGLPGPIGPKGEAGQKGVPGL--PGVPGLLGPKGEPGIPGDQGLQGPPGIPGIG 503 Query: 305 PPPGP--PPPQQGPPPPPG-PFPPRPP-----------GPLGPPLTLAP--PPHLPGPP- 347 P GP PP GP PG P PP P GP G P L P P LPGPP Sbjct: 504 GPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPG 563 Query: 348 PGAPPPAPHVNPAFFPPPTNSGMPTS--DSRGPPPTDPYGRPPPYDRGDYGPPGREM 402 P PP P V P PPP +P G P YG +G G P EM Sbjct: 564 PPGPPGPPAVMPP-TPPPQGEYLPDMGLGIDGVKPPHAYGA----KKGKNGGPAYEM 615 Score = 95.9 bits (237), Expect = 9e-20 Identities = 94/247 (38%), Positives = 105/247 (42%), Gaps = 38/247 (15%) Query: 178 GQMSGEGKAGPPG--GSSRAAFPQGGRGRGRFPGAV-----PGGDRFPGPAGPGGPPPPF 230 GQ +G GP G G P+G +G G PGA PG PGP G G P Sbjct: 217 GQPGPKGDRGPKGLPGPQGLRGPKGDKGFG-MPGAPGVKGPPGMHGPPGPVGLPGVGKPG 275 Query: 231 PAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPN-RGDRPPPPVLFPGQP-----F 284 G P+ PLG PG PG PGP P V P + GPP G P PGQP Sbjct: 276 VTGFPGPQGPLGKPGAPGEPGPQGPIGV--PGVQGPPGIPGIGKPGQDGIPGQPGFPGGK 333 Query: 285 GQPPLGPLPPGPPPPVPGYGPPPGP-PPPQQGPPPPPGPFPPR-PPGPLGPPLTLAPP-- 340 G+ L LP PP +PG G P P P +G PG PR GP+G P PP Sbjct: 334 GEQGLPGLP--GPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGE 391 Query: 341 PHLPG-PPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP-------PPYDR 392 P LPG P P PP A FP P G +GPP P G P P Sbjct: 392 PGLPGIPGPMGPPGA-----IGFPGPKGEG-GIVGPQGPP--GPKGEPGLQGFPGKPGFL 443 Query: 393 GDYGPPG 399 G+ GPPG Sbjct: 444 GEVGPPG 450 Score = 86.7 bits (213), Expect = 5e-17 Identities = 80/240 (33%), Positives = 98/240 (40%), Gaps = 37/240 (15%) Query: 184 GKAGPPG--GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP-------PPFPAGQ 234 G+ GPPG G P+G G+ PG +PG GP G G P PP G Sbjct: 444 GEVGPPGMRGLPGPIGPKGEAGQKGVPG-LPGVPGLLGPKGEPGIPGDQGLQGPPGIPGI 502 Query: 235 TPPRPPLGPPGPPGPPGPPP-PGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLP 293 P P+GPPG PGP G P PG P + P G PP P GQP L P P Sbjct: 503 GGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGL-PGP 561 Query: 294 PGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPP 353 PGPP P PGPP PPP G + P +G + PPH G G Sbjct: 562 PGPPGP-------PGPPAVMPPTPPPQGEYLP----DMGLGIDGVKPPHAYGAKKGKNGG 610 Query: 354 APHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAE 413 + PAF T++ P P P G P +++ Y GR+ +T + E Sbjct: 611 PAYEMPAF----------TAELTAPFP--PVGAPVKFNKLLYN--GRQNYNPQTGIFTCE 656 Score = 75.5 bits (184), Expect = 1e-13 Identities = 79/232 (34%), Positives = 93/232 (40%), Gaps = 44/232 (18%) Query: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFP-GPAGPGGPPPPFPAGQTPPRPPLGPPGP 246 P + A P+ G+ P A G++ P G GP GPP P P P G PG Sbjct: 95 PAPRMGKEAVPKKGK---EIPLASLRGEQGPRGEPGPRGPPGP------PGLPGHGIPGI 145 Query: 247 PGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQ--PFGQP----PLG-PLPPGPPPP 299 G PGP V P + G P + P + PG GQ P+G P P GPP P Sbjct: 146 KGKPGPQGYPGVGKPGMPGMPGK----PGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGP 201 Query: 300 --VPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPP-----HLPGPPPGAPP 352 +PG G P GP G P PGP R P L P L P +PG P P Sbjct: 202 HGLPGIGKPGGP-----GLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGP 256 Query: 353 PAPHVNPAFFPPPTNSGMPTSDSRG----PPPTDPYGRP-PPYDRGDYGPPG 399 P H PP G+P G P P P G+P P + G GP G Sbjct: 257 PGMH------GPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIG 302 Score = 32.7 bits (73), Expect = 0.89 Identities = 39/121 (32%), Positives = 45/121 (37%), Gaps = 14/121 (11%) Query: 281 GQPFGQPPLGP-LPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAP 339 G +G PL P +PP PP +P Y P Q P P G P L Sbjct: 28 GAYYGIKPLPPQIPPQMPPQIPQY------QPLGQQVPHMPLAKDGLAMGKEMPHLQYGK 81 Query: 340 P-PHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPP 398 PHLP PAP + P +P + RG P G P P RG GPP Sbjct: 82 EYPHLPQYMKEI-QPAPRMGKEAV-PKKGKEIPLASLRG--EQGPRGEPGP--RGPPGPP 135 Query: 399 G 399 G Sbjct: 136 G 136 >gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 102 bits (255), Expect = 7e-22 Identities = 105/297 (35%), Positives = 120/297 (40%), Gaps = 77/297 (25%) Query: 176 QSGQMSGEGKAGPPG--------GSSRAAF--PQGGRGRGRFPGAV-PGGDRFP-GPAGP 223 Q G G+G+ G PG G + F P+G RG G PGA+ P G++ P G G Sbjct: 326 QPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGI 385 Query: 224 GGPP--PPFPAGQTPPRPP--------------LGPPGPPGPPGPP-------------- 253 GGPP P P P PP +GP GPPGP G P Sbjct: 386 GGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGE 445 Query: 254 --PPG-QVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLG-PLPPGP-----PPPVPGYG 304 PPG + LP P+ G + P + PG P P G P PG PP +PG G Sbjct: 446 VGPPGMRGLPGPIGPKGEAGQKGVPGL--PGVPGLLGPKGEPGIPGDQGLQGPPGIPGIG 503 Query: 305 PPPGP--PPPQQGPPPPPG-PFPPRPP-----------GPLGPPLTLAP--PPHLPGPP- 347 P GP PP GP PG P PP P GP G P L P P LPGPP Sbjct: 504 GPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPG 563 Query: 348 PGAPPPAPHVNPAFFPPPTNSGMPTS--DSRGPPPTDPYGRPPPYDRGDYGPPGREM 402 P PP P V P PPP +P G P YG +G G P EM Sbjct: 564 PPGPPGPPAVMPP-TPPPQGEYLPDMGLGIDGVKPPHAYGA----KKGKNGGPAYEM 615 Score = 95.9 bits (237), Expect = 9e-20 Identities = 94/247 (38%), Positives = 105/247 (42%), Gaps = 38/247 (15%) Query: 178 GQMSGEGKAGPPG--GSSRAAFPQGGRGRGRFPGAV-----PGGDRFPGPAGPGGPPPPF 230 GQ +G GP G G P+G +G G PGA PG PGP G G P Sbjct: 217 GQPGPKGDRGPKGLPGPQGLRGPKGDKGFG-MPGAPGVKGPPGMHGPPGPVGLPGVGKPG 275 Query: 231 PAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPN-RGDRPPPPVLFPGQP-----F 284 G P+ PLG PG PG PGP P V P + GPP G P PGQP Sbjct: 276 VTGFPGPQGPLGKPGAPGEPGPQGPIGV--PGVQGPPGIPGIGKPGQDGIPGQPGFPGGK 333 Query: 285 GQPPLGPLPPGPPPPVPGYGPPPGP-PPPQQGPPPPPGPFPPR-PPGPLGPPLTLAPP-- 340 G+ L LP PP +PG G P P P +G PG PR GP+G P PP Sbjct: 334 GEQGLPGLP--GPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGE 391 Query: 341 PHLPG-PPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP-------PPYDR 392 P LPG P P PP A FP P G +GPP P G P P Sbjct: 392 PGLPGIPGPMGPPGA-----IGFPGPKGEG-GIVGPQGPP--GPKGEPGLQGFPGKPGFL 443 Query: 393 GDYGPPG 399 G+ GPPG Sbjct: 444 GEVGPPG 450 Score = 86.7 bits (213), Expect = 5e-17 Identities = 80/240 (33%), Positives = 98/240 (40%), Gaps = 37/240 (15%) Query: 184 GKAGPPG--GSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPP-------PPFPAGQ 234 G+ GPPG G P+G G+ PG +PG GP G G P PP G Sbjct: 444 GEVGPPGMRGLPGPIGPKGEAGQKGVPG-LPGVPGLLGPKGEPGIPGDQGLQGPPGIPGI 502 Query: 235 TPPRPPLGPPGPPGPPGPPP-PGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLP 293 P P+GPPG PGP G P PG P + P G PP P GQP L P P Sbjct: 503 GGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGL-PGP 561 Query: 294 PGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPP 353 PGPP P PGPP PPP G + P +G + PPH G G Sbjct: 562 PGPPGP-------PGPPAVMPPTPPPQGEYLP----DMGLGIDGVKPPHAYGAKKGKNGG 610 Query: 354 APHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAE 413 + PAF T++ P P P G P +++ Y GR+ +T + E Sbjct: 611 PAYEMPAF----------TAELTAPFP--PVGAPVKFNKLLYN--GRQNYNPQTGIFTCE 656 Score = 75.5 bits (184), Expect = 1e-13 Identities = 79/232 (34%), Positives = 93/232 (40%), Gaps = 44/232 (18%) Query: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFP-GPAGPGGPPPPFPAGQTPPRPPLGPPGP 246 P + A P+ G+ P A G++ P G GP GPP P P P G PG Sbjct: 95 PAPRMGKEAVPKKGK---EIPLASLRGEQGPRGEPGPRGPPGP------PGLPGHGIPGI 145 Query: 247 PGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQ--PFGQP----PLG-PLPPGPPPP 299 G PGP V P + G P + P + PG GQ P+G P P GPP P Sbjct: 146 KGKPGPQGYPGVGKPGMPGMPGK----PGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGP 201 Query: 300 --VPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPP-----HLPGPPPGAPP 352 +PG G P GP G P PGP R P L P L P +PG P P Sbjct: 202 HGLPGIGKPGGP-----GLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGP 256 Query: 353 PAPHVNPAFFPPPTNSGMPTSDSRG----PPPTDPYGRP-PPYDRGDYGPPG 399 P H PP G+P G P P P G+P P + G GP G Sbjct: 257 PGMH------GPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIG 302 Score = 32.7 bits (73), Expect = 0.89 Identities = 39/121 (32%), Positives = 45/121 (37%), Gaps = 14/121 (11%) Query: 281 GQPFGQPPLGP-LPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAP 339 G +G PL P +PP PP +P Y P Q P P G P L Sbjct: 28 GAYYGIKPLPPQIPPQMPPQIPQY------QPLGQQVPHMPLAKDGLAMGKEMPHLQYGK 81 Query: 340 P-PHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPP 398 PHLP PAP + P +P + RG P G P P RG GPP Sbjct: 82 EYPHLPQYMKEI-QPAPRMGKEAV-PKKGKEIPLASLRG--EQGPRGEPGP--RGPPGPP 135 Query: 399 G 399 G Sbjct: 136 G 136 >gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] Length = 639 Score = 102 bits (254), Expect = 9e-22 Identities = 91/271 (33%), Positives = 98/271 (36%), Gaps = 60/271 (22%) Query: 180 MSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRP 239 M G G GP GG P P G P P GPPPP+ PP P Sbjct: 382 MHGGGPGGPGGGPHSFPHP--------LPSLTGGHGGHPMQHNPNGPPPPW---MQPPPP 430 Query: 240 PLGP-PGPPGPPGPPPPGQVLPPPLAG--------------PPNRGDRPPPPVLFPGQPF 284 P+ P PPG GPPP Q L G PP G PPPP GQP Sbjct: 431 PMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQP- 489 Query: 285 GQPPLGPLPPG-------PPPPVPGYGPPPGPPPPQQ------------GPPPP------ 319 PP GPLPP PPPP P P P Q G PP Sbjct: 490 PPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQA 549 Query: 320 PGPFPPRPPGPLGPPLTLAPPPHLPGP-PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGP 378 P P G P + PP + P PPGAPPP P PPP ++GM + P Sbjct: 550 AAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPP------PPPGSAGMMYAPPPPP 603 Query: 379 -PPTDPYGRPPPYDRGDYGPPGREMDTARTP 408 PP DP G G P M A P Sbjct: 604 PPPMDPSNFVTMMGMGVAGMPPFGMPPAPPP 634 Score = 92.4 bits (228), Expect = 9e-19 Identities = 72/213 (33%), Positives = 81/213 (38%), Gaps = 48/213 (22%) Query: 188 PPGGSSRAAFPQGGRG---RGRFPGAVPGGDRF-----------PGPAGPGGPPPPFPAG 233 PP ++ P G G ++ G+ P G P P G PPPP P+G Sbjct: 428 PPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSG 487 Query: 234 QTPPRPPLGPPGP-------PGPPGPPPPGQVLPPPLAGPPNR---------GDRPP--- 274 Q PP PP GP P P PP PP PL N G PP Sbjct: 488 QPPP-PPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQ 546 Query: 275 ---PPVLFPGQPF--GQPPLGPLPPGPPPPVPGYGPPPGPPPPQQG-------PPPPPGP 322 PG P G P + PLPPG PP+P PPP PPPP PPPPP P Sbjct: 547 QQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPP 606 Query: 323 FPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAP 355 P + PP G PP PPP P Sbjct: 607 MDPSNFVTMMGMGVAGMPPF--GMPPAPPPPPP 637 Score = 82.8 bits (203), Expect = 7e-16 Identities = 64/188 (34%), Positives = 73/188 (38%), Gaps = 23/188 (12%) Query: 224 GGPPPPFPAGQT--PPRPPLGP-PGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFP 280 G P P G T P PL P P P PPP ++ + PP P + Sbjct: 321 GEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH 380 Query: 281 GQPFGQPP-LGPLPPGPPPPVP----GYGPPP------GPPPPQQGPPPPPGPFPPRPPG 329 G G P G P P P+P G+G P GPPPP PPPPP P PPG Sbjct: 381 GMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPG 440 Query: 330 PLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389 GPP +L P G+ H PPP MP PPP P G+PPP Sbjct: 441 HHGPP---PMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMP------PPPPPPSGQPPP 491 Query: 390 YDRGDYGP 397 G P Sbjct: 492 PPSGPLPP 499 Score = 82.0 bits (201), Expect = 1e-15 Identities = 74/226 (32%), Positives = 88/226 (38%), Gaps = 29/226 (12%) Query: 193 SRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPL-----GPPGPP 247 SR + G R + GG GP GPGG P FP P P L G P Sbjct: 364 SRPPWMNSGPSESRPYHGMHGG----GPGGPGGGPHSFPH----PLPSLTGGHGGHPMQH 415 Query: 248 GPPGPPPPGQVLPPPLAGPPNRGDRPP----PPVLFPGQPFGQPPLGPLPPGPPPPVPGY 303 P GPPPP PPP P N+G PP PP + Q G P+G G G Sbjct: 416 NPNGPPPPWMQPPPP---PMNQGPHPPGHHGPPPM--DQYLGSTPVGS---GVYRLHQGK 467 Query: 304 GPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFP 363 G P PPP PPPPP P PP P GP L P PP PPP+ + + Sbjct: 468 GMMP-PPPMGMMPPPPPPPSGQPPPPPSGP---LPPWQQQQQQPPPPPPPSSSMASSTPL 523 Query: 364 PPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPL 409 P + T+ S G P+ + G P + + PL Sbjct: 524 PWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPL 569 Score = 50.1 bits (118), Expect = 5e-06 Identities = 45/155 (29%), Positives = 57/155 (36%), Gaps = 24/155 (15%) Query: 270 GDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPG 329 G+ P P + G G P PL P P P PPP P RPP Sbjct: 321 GEAPVPASV--GSTSG-PATTPLASAPRPAAPANNPPP---------PSLMSTTQSRPPW 368 Query: 330 PLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPT--NSGMPTSDS-RGPPPTDPYGR 386 P P + G PG P PH P P T + G P + GPPP P+ + Sbjct: 369 MNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPP--PWMQ 426 Query: 387 PPP-------YDRGDYGPPGREMDTARTPLSEAEF 414 PPP + G +GPP + TP+ + Sbjct: 427 PPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVY 461 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 101 bits (252), Expect = 2e-21 Identities = 73/207 (35%), Positives = 80/207 (38%), Gaps = 25/207 (12%) Query: 208 PGAVPGGDRFPGP-AGPGGPPPPFPAGQTPPRPPLGPPGPPGPPG-PPPPGQVLPPPLAG 265 P P P P A P PP +PP PL P P PP PP Q P P A Sbjct: 580 PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS 639 Query: 266 PPNRGDRPPPP-------VLFPGQPFGQPPLGPL-----PPGPPPPVPGYGPPPGPP--- 310 PP P P V PF PP P+ PP PP P PP P Sbjct: 640 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 699 Query: 311 --PPQQGPPPPPGPFPPRP---PGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPP 365 PP Q PP PP P P P P PP APP +P PP +PP +P P PP Sbjct: 700 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPP 759 Query: 366 TNSGMPTSDSRGPP---PTDPYGRPPP 389 + P PP P P +PPP Sbjct: 760 LLAAPPLQVPPSPPASLPMSPLAKPPP 786 Score = 100 bits (249), Expect = 3e-21 Identities = 78/214 (36%), Positives = 84/214 (39%), Gaps = 34/214 (15%) Query: 227 PPPFPAGQTPPRPPLGPPGPPG--PPG--PP----PPGQVLPPPLAGPPNRGDRPPPPVL 278 PPP P Q P PP PP P PP PP PP QV P P A PP PPP Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 726 Query: 279 FPGQPFGQPPLG--PLPPGPPPPVPGYGPPPGPPP-----PQQGPPPPPGPFPPRP---P 328 P P PPL P PP PP P PPP PP P Q PP PP P P P Sbjct: 727 PP--PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP 784 Query: 329 GPLGPPLTLAPP-PHLPGPPPGAPPPAPH-------VNPAFFPPPTNSGMPTSDSRGPPP 380 P PP PP LP PP P AP ++P PPP + + PP Sbjct: 785 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 844 Query: 381 TDPYG------RPPPYDRGDYGPPGREMDTARTP 408 + P R PP D G + A P Sbjct: 845 SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 878 Score = 94.7 bits (234), Expect = 2e-19 Identities = 76/235 (32%), Positives = 92/235 (39%), Gaps = 29/235 (12%) Query: 208 PGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPP 267 P A P P A P PP P P P PP PP PP QV P P A PP Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPP 746 Query: 268 NRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVP----GYGPPPGPP----PPQQGPPPP 319 PPP + P PPL +PP PP +P PP PP PP Q P P Sbjct: 747 MSPSATPPPRVPP--LLAAPPL-QVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSP 803 Query: 320 PGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPP 379 P FP + P L ++P L PPP APP P PP+ PT + P Sbjct: 804 PASFPGQAPFSPSASLPMSP---LATPPPQAPPVL--AAPLLQVPPSPPASPTLQAPRRP 858 Query: 380 PTDPYGRPPPYDRGDYGP-------PGREMDTARTPLSEAEFEEIMNRNRAISSS 427 PT P D GP PG +R+P S ++ + + +S+ Sbjct: 859 PT------PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST 907 Score = 94.4 bits (233), Expect = 2e-19 Identities = 70/220 (31%), Positives = 79/220 (35%), Gaps = 50/220 (22%) Query: 220 PAGPGGPPPP-------FPAGQTPPRPPLGPP-GPPGPPGPPPPG----QVLPPPLAGPP 267 P P PPP P Q PP PP PP P P P P +L P + PP Sbjct: 610 PLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 669 Query: 268 NRGDRPP--PPVLFPGQPFGQPP-------------LGPLPPGPPPPVPGYGPPPGPPPP 312 + + P PP P P PP + P PP PP P PPP PPP Sbjct: 670 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 729 Query: 313 QQGPP------PPPGP--FPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPP 364 PP PP P P P P PPL APP +P PP + P +P P P Sbjct: 730 LAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAP 789 Query: 365 PTNSGMPTSDSRGPP---------------PTDPYGRPPP 389 P + P PP P P PPP Sbjct: 790 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829 Score = 87.8 bits (216), Expect = 2e-17 Identities = 80/259 (30%), Positives = 88/259 (33%), Gaps = 39/259 (15%) Query: 186 AGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPP-------FPAGQTPPR 238 A PP S Q P VP P P PPP P Q PP Sbjct: 681 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPS 740 Query: 239 PPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLP----- 293 PP PP P PP +PP LA PP + P PP P P +PP P Sbjct: 741 PPASPPMSPSATPPPR----VPPLLAAPPLQVP-PSPPASLPMSPLAKPPPQAPPALATP 795 Query: 294 -----PGPPPPVPGYGP---------PPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAP 339 P PP PG P P PP Q PP P PP P P AP Sbjct: 796 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 855 Query: 340 -PPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPP----PTDPYGRPPPYDRGD 394 P PGP P + A PPP S P+S GP + P D Sbjct: 856 RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD 915 Query: 395 YGPPGREMDTARTPLSEAE 413 GP G A +P +AE Sbjct: 916 SGPEG---GAAASPPPDAE 931 Score = 85.5 bits (210), Expect = 1e-16 Identities = 75/229 (32%), Positives = 84/229 (36%), Gaps = 20/229 (8%) Query: 186 AGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPP-------FPAGQTPPR 238 A PP S PQ P VP P P PPP P Q PP Sbjct: 712 ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPS 771 Query: 239 PPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQ-PFGQPPLGPLPPGPP 297 PP P P PPP PP LA PP + P PP FPGQ PF P LP P Sbjct: 772 PPASLP--MSPLAKPPPQA--PPALATPPLQA-LPSPPASFPGQAPFS--PSASLPMSPL 824 Query: 298 PPVPGYGPPPGPPPPQQGPPPPPGP----FPPRPPGPLGPPLTLAPPPHLPGPPPGAPPP 353 P PP P Q PP PP P RPP P GP +++ P PG PPP Sbjct: 825 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP-GPDTSVSGPRLTLALAPGPPPP 883 Query: 354 APHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREM 402 + P +G +S + P Y P PP E+ Sbjct: 884 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL 932 Score = 76.3 bits (186), Expect = 7e-14 Identities = 59/178 (33%), Positives = 65/178 (36%), Gaps = 26/178 (14%) Query: 231 PAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLG 290 P+ QTPP PP P PPP Q PL P + PP P P Q P Sbjct: 521 PSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTP--HLETPPCPAPCPLQAPPSPLTT 578 Query: 291 PLPPGP-----PPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPG 345 P P P PPP PP PP QG P PP P P P PP PP P Sbjct: 579 PPPETPSSIATPPP---QAPPALASPPLQGLPSPP-LSPLATPPPQAPPXLALPPLQAPP 634 Query: 346 PPPGAPPPAPHVNPA---------------FFPPPTNSGMPTSDSRGPPPTDPYGRPP 388 PP +PP +P P+ F PPP+ PP P PP Sbjct: 635 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 692 Score = 65.1 bits (157), Expect = 2e-10 Identities = 64/213 (30%), Positives = 74/213 (34%), Gaps = 43/213 (20%) Query: 220 PAGPGGPPPPFPAGQTPPRPPLGPP---------GPPGPPGPPPPGQVLPP--------P 262 P+ P PP P Q P P PP P P P Q L P Sbjct: 444 PSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAP 503 Query: 263 LAG---PP--NRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPP 317 L+ PP + PP + P PPL LP PPP+ P P + P Sbjct: 504 LSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPC 563 Query: 318 PPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRG 377 P P P PP PL PPP P PP AP PA PP G+P+ Sbjct: 564 PAPCPL-QAPPSPL-----TTPPPETPSSIATPPPQAP---PALASPPL-QGLPS----- 608 Query: 378 PPPTDPYGRPPPYDRGDYGPPGREMDTARTPLS 410 PP P PPP PP + + P S Sbjct: 609 -PPLSPLATPPP-----QAPPXLALPPLQAPPS 635 Score = 64.3 bits (155), Expect = 3e-10 Identities = 58/191 (30%), Positives = 70/191 (36%), Gaps = 22/191 (11%) Query: 239 PPLGPPGPPGPPG-PPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPP 297 PPL PP PP + PPL P+ PPP+ P P L P P Sbjct: 510 PPLETQSSLAPPSLQTPPASLTTPPLENLPSLA---PPPLQTASAPLTTPHLET--PPCP 564 Query: 298 PPVPGYGPP-PGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLP--GPPPGAPPPA 354 P P PP P PP + P P P PP PPL P P L PP PP Sbjct: 565 APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPX 624 Query: 355 PHVNPAFFPPPTNSGMPTSDSRGPPP-----------TDPYGRPP-PYDRGDYGPPGR-E 401 + P PP + P S P P P+ PP P + + PP Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 684 Query: 402 MDTARTPLSEA 412 + + TP S+A Sbjct: 685 VSPSATPPSQA 695 Score = 63.5 bits (153), Expect = 5e-10 Identities = 52/165 (31%), Positives = 63/165 (38%), Gaps = 11/165 (6%) Query: 220 PAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLF 279 P P P P P G RPP PP P G + PLA P G + P + Sbjct: 263 PRAPAHPSQPKPKGLQALRPP--QVTPPRKDAAPALGPLSSSPLATPSPSGTKARP--VP 318 Query: 280 PGQPFGQPPLGPLPPGPP--PPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTL 337 P P LPP PP P+P P P PP Q P PP P + P + P Sbjct: 319 PPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQ 378 Query: 338 APPPHLPGPPPGAPPPAPHVNPAFFPPPTN---SGMPTSDSRGPP 379 APP PP P +P+ PP+ S + + S G P Sbjct: 379 APPSLQTIPPIQVPHSL--TSPSLQAPPSPLALSSLQATTSLGSP 421 Score = 58.5 bits (140), Expect = 2e-08 Identities = 56/193 (29%), Positives = 64/193 (33%), Gaps = 48/193 (24%) Query: 207 FPGAVPGGDRFPGPAGPGGPPPP-------FPAGQTPPRPPLGP-------PGPPGP--- 249 FPG P P P PPP P Q PP PP P P PGP Sbjct: 807 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 866 Query: 250 -----------PGPPPPGQVLP------PPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPL 292 PGPPPP P P LAG + P + + + P G Sbjct: 867 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL----RGYDSGPEGGA 922 Query: 293 PPGPPPPVP-------GYGPPPGPPPPQQGPPPPPGPFPPRP-PGPLGPPLTL--APPPH 342 PPP + P PP +G P P P+PP PG T+ P Sbjct: 923 AASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPE 982 Query: 343 LPGPPPGAPPPAP 355 P PGA P P Sbjct: 983 SATPAPGALDPGP 995 Score = 55.1 bits (131), Expect = 2e-07 Identities = 51/171 (29%), Positives = 56/171 (32%), Gaps = 29/171 (16%) Query: 220 PAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLF 279 P+ GG P + PL P GP P P P PP V Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT- 286 Query: 280 PGQPFGQPPLGPLPPGP-PPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLA 338 P + P LGPL P P P PPP P P PP PP L PL LA Sbjct: 287 PPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPP--LATPLPLA 344 Query: 339 PPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389 PP P APP + T S PP P + PP Sbjct: 345 PPS------PSAPP----------------SLQTLPS---PPATPPSQAPP 370 Score = 53.5 bits (127), Expect = 5e-07 Identities = 49/151 (32%), Positives = 53/151 (35%), Gaps = 20/151 (13%) Query: 243 PPGPPGPPGPPPPG-QVLPPPLAGPPNRGDRPPPPVLFPGQPFGQP-PLGPLPPGPPPPV 300 P P P P P G Q L PP PP R D P P P P G PPP Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPP-RKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321 Query: 301 PGYGPPPG---PPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHV 357 P P P PP P P P P PP +L P P PP PP+ Sbjct: 322 NAATPLPATLPPSPPLATPLPLAPPSPSAPP-------SLQTLPSPPATPPSQAPPSMTT 374 Query: 358 NPAFFPPPTNSGMP-------TSDSRGPPPT 381 P PP + P TS S PP+ Sbjct: 375 PPMQAPPSLQTIPPIQVPHSLTSPSLQAPPS 405 Score = 51.6 bits (122), Expect = 2e-06 Identities = 72/277 (25%), Positives = 86/277 (31%), Gaps = 53/277 (19%) Query: 178 GQMSGEGKAGP-PGGSSRAAFPQGGRGRGRFPGAVPGGDRF--PGPAGPGGPPPPFPAGQ 234 G +S A P P G+ P P +P P P P P P P+ Q Sbjct: 297 GPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAP-PSLQ 355 Query: 235 TPPRPPLGPPGPPGPPG---PP---PPGQVLPPPLAGPPNRG----DRPPPPVLFP---- 280 T P PP PP PP PP PP PP+ P + PP P+ Sbjct: 356 TLPSPPATPP-SQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQA 414 Query: 281 ----GQPFGQPPLGPLPPGPPPPVPGYGPP--PGPPPPQQGPPPPPGPFPPRPP------ 328 G P Q L P P P PP P P P PP Sbjct: 415 TTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLS 474 Query: 329 ---GPLGPPLTLAP-------PPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGP 378 PL PLT+ P H P P + P + PP+ P S + P Sbjct: 475 PAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPP 534 Query: 379 PPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAEFE 415 P PPP + TA PL+ E Sbjct: 535 LENLPSLAPPP------------LQTASAPLTTPHLE 559 Score = 44.7 bits (104), Expect = 2e-04 Identities = 62/241 (25%), Positives = 72/241 (29%), Gaps = 65/241 (26%) Query: 232 AGQTPPR--PPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPG-----QPF 284 A +TP P L P PPG P PPPP + G R P G P Sbjct: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72 Query: 285 GQPPLGPL--------PPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRP-----PGPL 331 P GP P PP G G PP + P P P R PGPL Sbjct: 73 SAPRAGPTRSAGTSSRNPASRPPASGRGE---RAPPAKNTSPGPVSSPGRASGTTRPGPL 129 Query: 332 G-----------------------PPLTLAPPPHLPGPPPGAPPPA-------------- 354 G L+ GP PG P PA Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189 Query: 355 PHVNPAFFPPPTNSG-----MPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPL 409 P P+ P P G S+ P+ R P G P R + ++ TPL Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249 Query: 410 S 410 S Sbjct: 250 S 250 Score = 34.7 bits (78), Expect = 0.23 Identities = 31/102 (30%), Positives = 32/102 (31%), Gaps = 15/102 (14%) Query: 208 PGAVPGGDRFPGPAGPGGPPPPFP-------AGQTPPRPPLGPPGPPGPPGPPPPGQVLP 260 P + G D P PPP A P PPL G PG P P PP Sbjct: 908 PEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP----- 962 Query: 261 PPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPG 302 A P D G P G L PGP P G Sbjct: 963 ---ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSG 1001 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.139 0.442 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 41,106,541 Number of Sequences: 37866 Number of extensions: 4516720 Number of successful extensions: 168060 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 2008 Number of HSP's successfully gapped in prelim test: 2079 Number of HSP's that attempted gapping in prelim test: 20670 Number of HSP's gapped (non-prelim): 40182 length of query: 551 length of database: 18,247,518 effective HSP length: 107 effective length of query: 444 effective length of database: 14,195,856 effective search space: 6302960064 effective search space used: 6302960064 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.