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Search of human proteins with 158854042
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
(653 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 1336 0.0
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 252 9e-67
gi|50083281 KIAA1853 protein [Homo sapiens] 210 4e-54
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 134 3e-31
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 120 5e-27
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 99 2e-20
gi|153251865 hypothetical protein LOC84226 [Homo sapiens] 96 8e-20
gi|57864582 hornerin [Homo sapiens] 96 1e-19
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 92 1e-18
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] 92 2e-18
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 91 3e-18
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] 91 3e-18
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] 91 3e-18
gi|60097902 filaggrin [Homo sapiens] 87 5e-17
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 87 6e-17
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 84 5e-16
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 82 1e-15
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 82 1e-15
gi|50962882 G patch domain containing 8 [Homo sapiens] 81 3e-15
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 80 5e-15
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 78 3e-14
gi|239754474 PREDICTED: similar to mucin [Homo sapiens] 76 9e-14
gi|42821110 hypothetical protein LOC340602 [Homo sapiens] 76 9e-14
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 72 2e-12
gi|182507165 thymus expressed gene 3-like [Homo sapiens] 71 4e-12
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 70 5e-12
gi|221139764 PHD and ring finger domains 1 [Homo sapiens] 70 6e-12
gi|167234419 thyroid hormone receptor associated protein 3 [Homo... 70 6e-12
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 69 1e-11
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 68 2e-11
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 1336 bits (3457), Expect = 0.0
Identities = 653/653 (100%), Positives = 653/653 (100%)
Query: 1 MSSTVNNGAASMQSTPDAANGFPQPSSSSGTWPRAEEELRAAEPGLVKRAHREILDHERK 60
MSSTVNNGAASMQSTPDAANGFPQPSSSSGTWPRAEEELRAAEPGLVKRAHREILDHERK
Sbjct: 1 MSSTVNNGAASMQSTPDAANGFPQPSSSSGTWPRAEEELRAAEPGLVKRAHREILDHERK 60
Query: 61 RRVELKCMELQEMMEEQGYSEEEIRQKVGTFRQMLMEKEGVLTREDRPGGHIVAETPRLT 120
RRVELKCMELQEMMEEQGYSEEEIRQKVGTFRQMLMEKEGVLTREDRPGGHIVAETPRLT
Sbjct: 61 RRVELKCMELQEMMEEQGYSEEEIRQKVGTFRQMLMEKEGVLTREDRPGGHIVAETPRLT 120
Query: 121 EGAEPGLEYAPFDDDDGPVDCDCPASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRR 180
EGAEPGLEYAPFDDDDGPVDCDCPASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRR
Sbjct: 121 EGAEPGLEYAPFDDDDGPVDCDCPASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRR 180
Query: 181 SRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEK 240
SRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEK
Sbjct: 181 SRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEK 240
Query: 241 KRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSP 300
KRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSP
Sbjct: 241 KRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSP 300
Query: 301 SPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARG 360
SPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARG
Sbjct: 301 SPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARG 360
Query: 361 KESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSS 420
KESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSS
Sbjct: 361 KESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSS 420
Query: 421 RSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRR 480
RSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRR
Sbjct: 421 RSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRR 480
Query: 481 GGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRA 540
GGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRA
Sbjct: 481 GGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRA 540
Query: 541 RHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSS 600
RHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSS
Sbjct: 541 RHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSS 600
Query: 601 DYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESGGF 653
DYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESGGF
Sbjct: 601 DYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESGGF 653
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 252 bits (643), Expect = 9e-67
Identities = 232/670 (34%), Positives = 313/670 (46%), Gaps = 92/670 (13%)
Query: 34 RAEEELRAAEPGLVKRAHREILDHERKRRVELKCMELQEMMEEQGYSEEEIRQKVGTFRQ 93
+ EEELR E LVKR + +ILDHERKRRVEL+C+EL+EMMEEQGY E++I++KV TFR
Sbjct: 37 KGEEELRRLEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRL 96
Query: 94 MLMEKE-GVLTREDRPGGH-IVAETPRLTEGAEPGLE--YAPFDDDDGPVD--------- 140
ML+EK+ +E+ PG V ET +L E E E A F D VD
Sbjct: 97 MLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRR 156
Query: 141 -CDCPASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPL 199
+ + Y SSSS SP PK+KKKKK +K R SE SSSP
Sbjct: 157 AREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKK------KKDRGRRSE----SSSPR 206
Query: 200 RKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGS 259
R++KKS KK ++ RS+S S +KR+HRS + K KRK K+K++KR + +P +S R +
Sbjct: 207 RERKKSSKK-KKHRSESES-KKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRST 264
Query: 260 SHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQ 319
S + SS S SRS S + H + RSPSP+ G G
Sbjct: 265 SADSASSSDTSRSRSRSAAAKTH---------TTALAGRSPSPASGRRGEGDAPFSEPGT 315
Query: 320 RSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTP-PARGKESPSPRSAPS---SQGR 375
S P +A P P + + + +A P+P P R P P AP+ ++
Sbjct: 316 TSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEP-PAPTPLLAERH 374
Query: 376 GGRAAGGAGRRRRRRRRRRRSRSSAS---APRRRGRRRPRPAPPRGSSRSLSRARSSSDS 432
GG A + S +S + +P + + P+ + S S + S +
Sbjct: 375 GGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHA 434
Query: 433 GSGRGAPGPGPEPGSER--------GHGGHGKRAKER-----PPRARPASTSPSPGAHGR 479
S +P P P PGS R + HG+ +++ P R S SP+ GR
Sbjct: 435 SSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGR 494
Query: 480 RGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEK--RPHSP---SRSPSPKKP---LS 531
SRS P R S SRSP RSRSA++ R SP RS SP++P S
Sbjct: 495 ---------SRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRS 545
Query: 532 RDKDGEGRAR-------HSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRP- 583
R+ GR+R HS + ATR R RSR+ + + R +P+ R T R+R
Sbjct: 546 RNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSR 605
Query: 584 --IPYYR-----PSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSR 636
P R +P+ S S RS SRSP + S SRS R RS SR
Sbjct: 606 SRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSP----ARRSGRSRSRTPARRGRSRSR 661
Query: 637 TPSPSYHSRS 646
TP+ SRS
Sbjct: 662 TPARRGRSRS 671
Score = 134 bits (337), Expect = 3e-31
Identities = 158/555 (28%), Positives = 226/555 (40%), Gaps = 79/555 (14%)
Query: 122 GAEPGLEYAPFDDDDGPVDCDCPASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRS 181
G+ PG++ P G +CD +SP PK + RS
Sbjct: 1461 GSSPGMKDIPRTPSRGRSECD---------------------SSPEPKALPQTPRPRSRS 1499
Query: 182 RKKRRLESEC------SCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKE 235
L ++C GS S + +K + + RS SGS ++ + +S +R E
Sbjct: 1500 PSSPELNNKCLTPQRERSGSESSVDQKTVA-RTPLGQRSRSGSSQELDVKPSASPQERSE 1558
Query: 236 KNKEK-KRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRS 294
+ + T +P R+ R SGSS S S RS S SP+ +D+ R +S
Sbjct: 1559 SDSSPDSKAKTRTPLRQRSR--SGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQS 1616
Query: 295 SGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRP---GSAHSPPDKPSSPSPRVRDKAAA 351
SP P + P+R+ SG S G P S S P+ P P R + +
Sbjct: 1617 GSDSSPEPKAPAPRALPRRSR-SGSSSKGRGPSPEGSSSTESSPEHP--PKSRTARRGSR 1673
Query: 352 AAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRP 411
++P P + + P RS+ SS R+ R RRSRS++S+P R R P
Sbjct: 1674 SSPEPKTKSRTPPRRRSSRSSP-----------ELTRKARLSRRSRSASSSPETRSRTPP 1722
Query: 412 R-----------PAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKE 460
R PA SSR A S + R P P+P + +R K
Sbjct: 1723 RHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKT 1782
Query: 461 RPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSS---SRSPSKSR-SRSAEKR 516
R R R S S + R+ +S SRS R S SRSP++ SR++ +R
Sbjct: 1783 RTTRRRDRSGSSQSTSRRRQ-----RSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRR 1837
Query: 517 PHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRA-RRRSRSYSPIRKRRRDSPSFMEPRR 575
SR+P + SR + + S + A+ A RRSRS +P+ RRR S S P
Sbjct: 1838 RRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRR-SRSRTSPVS 1896
Query: 576 ITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPS 635
+R R R S S +S +R SRS +P + SR+ TR R+R S
Sbjct: 1897 RRRSRSRTSVTRRRSRSRASPV------SRRRSRSRTPPVTRRRSRSRTPTTRRRSR--S 1948
Query: 636 RTPSPSYHSRSSSES 650
RTP P RS S +
Sbjct: 1949 RTP-PVTRRRSRSRT 1962
Score = 128 bits (321), Expect = 2e-29
Identities = 161/518 (31%), Positives = 209/518 (40%), Gaps = 68/518 (13%)
Query: 161 SSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRR 220
S S S P K K + +RSR SSP KS RR RS S
Sbjct: 1557 SESDSSPDSKAKTRTPLRQRSRS-----------GSSP-EVDSKSRLSPRRSRSGSSPEV 1604
Query: 221 KRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSP 280
K + R+ + + E K P + RRS SS PS S SP P
Sbjct: 1605 KDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEH-PP 1663
Query: 281 KHRD--EGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKP 338
K R G ++ + + SR+P P S SP+ R R SA S P+
Sbjct: 1664 KSRTARRGSRSSPEPKTKSRTP-PRRRSSRSSPELT-----RKARLSRRSRSASSSPETR 1717
Query: 339 SSPSPRVRDKAAAAAPTPPARGKESPSPRSA--------------PSSQGRGGRAAGGAG 384
S PR R + ++P P + + S RSA PS + RG + +
Sbjct: 1718 SRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRS 1777
Query: 385 RRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPE 444
RR + R RRR RS +S R R+R SRS SR GSG + P +
Sbjct: 1778 RREKTRTTRRRDRSGSSQSTSRRRQR---------SRSRSRVTRRRRGGSGYHSRSPARQ 1828
Query: 445 PGSERGHGGHGKRAKER-PPRARPAS---TSPSPGAHGR-RGGPEGKSSSRSPGP----- 494
S +R + R PP +R S TSP+P R R P SRS P
Sbjct: 1829 ESSRTS--SRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRR 1886
Query: 495 HPRSWSSSRSPSKSRSRSAEKRPHSPSRSP--SPKKPLSRDKDGEGRARHSEAEATRARR 552
RS +S S +SRSR++ R S SR+ S ++ SR R S TR R
Sbjct: 1887 RSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRS 1946
Query: 553 RSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPS 612
RSR+ P+ +RR S + RR + +R PI R S S S RS SR+ S
Sbjct: 1947 RSRT-PPVTRRRSRSRTPPVTRRRSRSRTSPITRRR-----SRSRTSPVTRRRSRSRT-S 1999
Query: 613 PGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSES 650
P S S S TR R+R SRTP P+ RS S +
Sbjct: 2000 PVTRRRSRSRTSPVTRRRSR--SRTP-PAIRRRSRSRT 2034
Score = 127 bits (320), Expect = 2e-29
Identities = 151/558 (27%), Positives = 218/558 (39%), Gaps = 65/558 (11%)
Query: 149 RGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKK 208
R R + S S SP + + + + RR R + R + S +P R++ +S
Sbjct: 550 RRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTP 609
Query: 209 HRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSH 268
RR RS S + +RR R+RS +R+ +++ R S R R S +P+
Sbjct: 610 ARRGRSRSRTPARRRSRTRSP-VRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGR 668
Query: 269 YSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRP 328
S SR+P+R S + R R + S SR+P G S S R G S R+ GR
Sbjct: 669 -SRSRTPARRSGRSRS--RTPARRGRSRSRTPR-RGRSRSRSLVRRGRSHSRTPQRRGRS 724
Query: 329 GSAHSPPDKPSSPSPRVRDKAAAA---APTPPARGKESPSPRSAPSSQGRGGRAAGGAGR 385
GS+ +K + R R ++ + R + SPRS S+ R+ G+
Sbjct: 725 GSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSP 784
Query: 386 --RRRRRRRRRRSRSSASAPRRRGRRRPRPA------PPRGSSRSLSRARSSSDSGSGRG 437
+++ + RRSRS +S P+ + R PR + PP+ S++ SR SS S +
Sbjct: 785 CPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKV 844
Query: 438 APGPGPEPGS-------ERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSR 490
G P GS E+ + E P P S +P H G + S
Sbjct: 845 KSGTPPRQGSITSPQANEQSVTPQRRSCFESSPD--PELKSRTPSRHSCSGSSPPRVKSS 902
Query: 491 SPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRA---------- 540
+P S SSS P S +R HS S SPSP + SR R+
Sbjct: 903 TPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESR 962
Query: 541 ---RHSEA-----------EATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPY 586
R+S + E + S S SP K + +P P S K P P
Sbjct: 963 LLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTP----PGPSLSGSKSPCPQ 1018
Query: 587 YRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSS--------RSHGTRSRTRSP---- 634
+ S SC S S PG S+ SS S RS T SP
Sbjct: 1019 EKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQ 1078
Query: 635 SRTPSPSYHSRSSSESGG 652
S + SPS S+S + G
Sbjct: 1079 SHSESPSLQSKSQTSPKG 1096
Score = 115 bits (289), Expect = 1e-25
Identities = 163/552 (29%), Positives = 227/552 (41%), Gaps = 81/552 (14%)
Query: 144 PASCYRGH-RGYRTKHWSSS-------SASPPPKKKKKK------KGGHRRSRKK--RRL 187
P S R H R R K S + S SP K+ + K GH RSR RR
Sbjct: 457 PTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRS 516
Query: 188 ESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTES 247
S G S +++ +S R S S + + RR RSRS++ R R + S
Sbjct: 517 RSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQ-RRGRSRSARRGRSHSRSPATRGRSRS 575
Query: 248 --PGRRSHRHS----SGSSHSPSLSSHYSDSRSPSR------LSPKHRDEGRKTGSQRSS 295
P RR S S S + + S SR+P+R +P R ++ +R S
Sbjct: 576 RTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRS 635
Query: 296 GSRSPS-PSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAP 354
SRSP+ SG S +P R G S R+ A GR S +P + R + +
Sbjct: 636 RSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRS-RTPARRSGRSRSRTPARRGRSRS 694
Query: 355 TPPARGKESPSP-----RSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRR 409
P RG+ RS + R GR+ + R+ + R +RRSRS++S ++ R
Sbjct: 695 RTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRI 754
Query: 410 RPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPAS 469
R R S S R+++ S R G P P K+ + PPR
Sbjct: 755 SSR----RSRSLSSPRSKAKSRLSLRRSLSGSSPCP----------KQKSQTPPR----- 795
Query: 470 TSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPK-K 528
R G + K+ SR+ P RS SSS P K +S++ ++ HS S SP PK K
Sbjct: 796 -------RSRSGSSQPKAKSRT--PPRRSRSSSSPPPKQKSKTPSRQSHS-SSSPHPKVK 845
Query: 529 PLSRDKDGEGRARHSEAEATRARRRS---RSYSPIRKRR---RDSPSFMEPRRI-TSARK 581
+ + G + + ++ +RRS S P K R R S S P R+ +S
Sbjct: 846 SGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPP 905
Query: 582 RPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSP-----SR 636
R P SP + S RSHS S SP S +SR+ RSR+ SP SR
Sbjct: 906 RQSPSRSSSPQPKVKAIISP-RQRSHSGSSSPSPSR--VTSRTTPRRSRSVSPCSNVESR 962
Query: 637 TPSPSYHSRSSS 648
HS SSS
Sbjct: 963 LLPRYSHSGSSS 974
Score = 111 bits (277), Expect = 2e-24
Identities = 158/564 (28%), Positives = 222/564 (39%), Gaps = 80/564 (14%)
Query: 113 VAETPRLTEGAEPGLEYAPFDDDDGPVDCDCPASCYRGH----RGYRTKHWSSSSASP-- 166
V + PR A+ G + +P + P P G RG + SS+ +SP
Sbjct: 1604 VKDKPRAAPRAQSGSDSSP--EPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEH 1661
Query: 167 PPKKKKKKKGGHR--RSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKR-- 222
PPK + ++G + K R SSP +K + + R S S R R
Sbjct: 1662 PPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTP 1721
Query: 223 -RHRSRSSKCKRK--EKNKEKKRPHTESPGRRSHRHSSGSSHSPS---LSSHYSDSRSPS 276
RHR S + EK++ +R + S R G S SP L S SR
Sbjct: 1722 PRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREK 1781
Query: 277 RLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPD 336
+ + RD ++GS +S+ SR S + +R GGSG S + + S S
Sbjct: 1782 TRTTRRRD---RSGSSQST-SRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRR 1837
Query: 337 KPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRR---- 392
+ + + + T PA K S S R++P++ R RRR R R
Sbjct: 1838 RRGRSRTPPTSRKRSRSRTSPAPWKRSRS-RASPATHRRSRSRTPLISRRRSRSRTSPVS 1896
Query: 393 RRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHG 452
RRRSRS S RRR R R P SR SR+R+ P + R
Sbjct: 1897 RRRSRSRTSVTRRRSRSRASPV-----SRRRSRSRTP---------------PVTRR--- 1933
Query: 453 GHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRS 512
R++ R P R S S +P RR S SR+P R S SP R
Sbjct: 1934 ----RSRSRTPTTRRRSRSRTPPVTRRR------SRSRTPPVTRRRSRSRTSPITRRRSR 1983
Query: 513 AEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSP--IRKRRRDSPSF 570
+ P + RS S P++R + R+R S RRRSRS +P IR+R R
Sbjct: 1984 SRTSPVTRRRSRSRTSPVTRRRS---RSRTSPV----TRRRSRSRTPPAIRRRSRSRTPL 2036
Query: 571 MEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRS- 629
+ +R S + P+ R S S + + RS +RSP + S S +RS
Sbjct: 2037 LPRKR--SRSRSPLAIRRRSRSRTP---RTARGKRSLTRSPPAIRRRSASGSSSDRSRSA 2091
Query: 630 -----RTRSPSRTPSPSYHSRSSS 648
R S SRTP + +S S
Sbjct: 2092 TPPATRNHSGSRTPPVALNSSRMS 2115
Score = 105 bits (263), Expect = 1e-22
Identities = 149/506 (29%), Positives = 189/506 (37%), Gaps = 107/506 (21%)
Query: 239 EKKRPHTESPGRRSHRHS------SGSSHSPSLSSHYSDS--------RSPSRLSPKHRD 284
+ K T S G S S +G S + S+SS D+ RS S SP+ +D
Sbjct: 1370 DMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKD 1429
Query: 285 EGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHG-------GRPGSAHSPPDK 337
+T S+RS SP GS G+P R+ SG G GR SP K
Sbjct: 1430 GLPRTPSRRSRSGSSPGLRDGS--GTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPK 1487
Query: 338 --PSSPSPRVRDKAA------------------------AAAPTPPARGKESPS------ 365
P +P PR R ++ A TP + S S
Sbjct: 1488 ALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDV 1547
Query: 366 -PRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSA---SAPRRRGRRRPRPAPP--RGS 419
P ++P + + + R R+R RS SS S R RR + P +
Sbjct: 1548 KPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDK 1607
Query: 420 SRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAH-- 477
R+ RA+S SDS AP P P R G +K R P +S++ S H
Sbjct: 1608 PRAAPRAQSGSDSSPEPKAPAPRALPRRSRS----GSSSKGRGPSPEGSSSTESSPEHPP 1663
Query: 478 -------GRRGGPEGKSSSRSPGPHPRSWSSSRSP-----------SKSRSRSAEKRPHS 519
G R PE K+ SR+P PR SS SP S+S S S E R +
Sbjct: 1664 KSRTARRGSRSSPEPKTKSRTP---PRRRSSRSSPELTRKARLSRRSRSASSSPETRSRT 1720
Query: 520 P---SRSPSPKKPLSRDKDGEGRARHS----EAEATRARRRSRSYSPIRKRRRDSPSFME 572
P RSPS P +K R R S + T R RS S P +R S S E
Sbjct: 1721 PPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRRE 1780
Query: 573 PRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRS------HSRSPSPGHSHGSYSSRSHG 626
R T R R S S S + R HSRSP+ S + S R G
Sbjct: 1781 KTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRG 1840
Query: 627 -----TRSRTRSPSRT-PSPSYHSRS 646
SR RS SRT P+P SRS
Sbjct: 1841 RSRTPPTSRKRSRSRTSPAPWKRSRS 1866
Score = 88.6 bits (218), Expect = 2e-17
Identities = 127/510 (24%), Positives = 186/510 (36%), Gaps = 78/510 (15%)
Query: 161 SSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSS--PLRKKKKSVKKHRRDRSDSGS 218
S S +P + + + + RR R + R + S S S P R+ + + RR RS S S
Sbjct: 647 SRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRS 706
Query: 219 --RRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPS 276
RR R H + R + E+K + R S R S +S S S RS S
Sbjct: 707 LVRRGRSHSRTPQRRGRSGSSSERK-----NKSRTSQRRSRSNSSPEMKKSRISSRRSRS 761
Query: 277 RLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQ---RSGAHGGRPGSAHS 333
SP+ + + R + + SGS SP P S + GS Q +S R S+ S
Sbjct: 762 LSSPRSKAKSRLSLRRSLSGS-SPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSS 820
Query: 334 PPDKPSSPSPRVRDKAAAAAP-------TPPARGK-ESPSPRSAPSSQGRGGRAAGGAGR 385
PP K S +P R ++++P TPP +G SP + R
Sbjct: 821 PPPKQKSKTPS-RQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDP 879
Query: 386 RRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSS-----RSLSRARSSSDSGSGRGAPG 440
+ R R S S +S PR + PR +P R SS +++ R S SGS +P
Sbjct: 880 ELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPS 939
Query: 441 PGPEPGSER-------------------GHGGHG----KRAKERPPR-ARPASTSPSPGA 476
+ R H G K E PPR + S SP P
Sbjct: 940 RVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKV 999
Query: 477 HGRRGGPEGKSSSRSPGPHPRSWSS-----------------SRSPSKSRSRSAE----- 514
+ S S+SP P +S S S P +S +
Sbjct: 1000 KAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKG 1059
Query: 515 KRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPR 574
+ SP P R E + S+++ + RSRS SP+ + SP +
Sbjct: 1060 QSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRG 1119
Query: 575 RITSARKRPIPYYRPSPSSSSSCLSSDYST 604
+++ P + S S SD S+
Sbjct: 1120 EFSAS-----PMLKSGMSPEQSRFQSDSSS 1144
Score = 87.4 bits (215), Expect = 4e-17
Identities = 124/429 (28%), Positives = 166/429 (38%), Gaps = 84/429 (19%)
Query: 157 KHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLR-----------KKKKS 205
+H S S S P +K + RRS R ++ G S + +++K+
Sbjct: 1723 RHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKT 1782
Query: 206 VKKHRRDRSDSG---SRRKRRHRSRSSKCKRKEKNK--EKKRPHTESPGRRSHRHSSGSS 260
RRDRS S SRR++R RSRS +R+ + P + R S R G S
Sbjct: 1783 RTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRS 1842
Query: 261 HSPSLSSHYSDSR--------SPSRLSPK-HRDEGRKTG--SQRSSGSR-SPSPSGGSGW 308
+P S S SR S SR SP HR +T S+R S SR SP S
Sbjct: 1843 RTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRS 1902
Query: 309 GSPQRNGGSGQRSGAHGGRPGSAHSPP---DKPSSPSPRVRDKAAAAAP----------T 355
+ S R+ R + +PP + S +P R ++ + P T
Sbjct: 1903 RTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRT 1962
Query: 356 PPA---RGKESPSP--------RSAPSSQGRGGRAAGGAGRRRRRRRR----RRRSRSSA 400
PP R + SP R++P ++ R RRR R R RRRSRS
Sbjct: 1963 PPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRT 2022
Query: 401 SAPRRRGRRRPRPAPPRGSSRSLS--RARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRA 458
RR R P PR SRS S R S S + R A GKR+
Sbjct: 2023 PPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTA---------------RGKRS 2067
Query: 459 KER-PPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRP 517
R PP R S S G +S S +P P R+ S SR+P + + S
Sbjct: 2068 LTRSPPAIRRRSAS---------GSSSDRSRSATP-PATRNHSGSRTPPVALNSSRMSCF 2117
Query: 518 HSPSRSPSP 526
PS SP+P
Sbjct: 2118 SRPSMSPTP 2126
Score = 73.2 bits (178), Expect = 7e-13
Identities = 92/364 (25%), Positives = 133/364 (36%), Gaps = 42/364 (11%)
Query: 242 RPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSR--- 298
R + +P + S +PS SS + S S L P S S SR
Sbjct: 2404 RARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLI 2463
Query: 299 -SPSPSGGSGWGSPQRNGGSGQRSGAHGGR-----PGSAHSPPDKPSSPS---------- 342
+P GS S + +G H G PG HS +P + +
Sbjct: 2464 AQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAA 2523
Query: 343 --PRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSA 400
P ++++++ + + S S S+ SS G + G+ + +R S
Sbjct: 2524 LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT 2583
Query: 401 SAPRRRGR--RRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRA 458
AP+ R R P P P + RS S + SSS S S + S +
Sbjct: 2584 PAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643
Query: 459 KERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPH 518
+ P+ P P A + P + P P R S R P S R + +
Sbjct: 2644 SSS---SSPSPAKPGPQALPKPASP------KKPPPGERRSRSPRKPIDS-LRDSRSLSY 2693
Query: 519 SP--SRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRI 576
SP R PSP +P RD+ R S R +R S SP KRRR++PS P R
Sbjct: 2694 SPVERRRPSP-QPSPRDQQSSSSERGS-----RRGQRGDSRSPSHKRRRETPS-PRPMRH 2746
Query: 577 TSAR 580
S+R
Sbjct: 2747 RSSR 2750
Score = 70.5 bits (171), Expect = 5e-12
Identities = 71/238 (29%), Positives = 84/238 (35%), Gaps = 22/238 (9%)
Query: 183 KKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKR--------K 234
K+RR S S SSS S S S S KR K
Sbjct: 2528 KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPK 2587
Query: 235 EKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRS 294
E +E RP +P +R R SS SS S S SS S S S S + S S
Sbjct: 2588 EAVREG-RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSS------------SSSSSS 2634
Query: 295 SGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRD-KAAAAA 353
S S S S S S SP + G A +P P P +RD ++ + +
Sbjct: 2635 SSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYS 2694
Query: 354 PTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRP 411
P R PSPR SS G G G R +RRR S R R R P
Sbjct: 2695 PVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
Score = 61.6 bits (148), Expect = 2e-09
Identities = 68/257 (26%), Positives = 90/257 (35%), Gaps = 40/257 (15%)
Query: 282 HRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSP 341
H D G S +G++ PS +R+ S S + S+ S S
Sbjct: 2503 HSDVGEPPAS---TGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSS 2559
Query: 342 SPRVRDKAAAAAPTPPARG-KESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSA 400
S D ++ P P K PSP AP R GR +R+RR S SS+
Sbjct: 2560 SS---DSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSS 2616
Query: 401 SAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPG----------PEPGSERG 450
S+ + SS S S + SSS S S PGP P PG R
Sbjct: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSP-AKPGPQALPKPASPKKPPPGERRS 2675
Query: 451 HG--------------GHGKRAKERP-----PRARPASTSPSPGAHGRRG---GPEGKSS 488
+ + RP PR + +S+S G+RG P K
Sbjct: 2676 RSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRR 2735
Query: 489 SRSPGPHPRSWSSSRSP 505
+P P P SSRSP
Sbjct: 2736 RETPSPRPMRHRSSRSP 2752
Score = 60.1 bits (144), Expect = 6e-09
Identities = 113/435 (25%), Positives = 156/435 (35%), Gaps = 68/435 (15%)
Query: 257 SGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRK---TGSQRSSGSRSPSPSGGSGWGSPQR 313
+GS P+ +++ S SR+P + + R T +GSR+ + + S +
Sbjct: 2312 TGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARM 2371
Query: 314 NGGSGQRSGAHGGRPGSAHSPPDKPSS-PSPRVRDKAAAAAPTPPARGKESPSPRSAPSS 372
+ SGA+ P S ++ S SP + D+A + P P A + + APS
Sbjct: 2372 ---APALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTP-PSAPSQSRMTSERAPSP 2427
Query: 373 QGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDS 432
R G+A + + + R S+ S R + P S S + A ++S +
Sbjct: 2428 SSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSA 2487
Query: 433 GSGRG---APGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSS 489
G G P PG H G+ + A + P R SSS
Sbjct: 2488 GDHNGMLSVPAPGVP------HSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSS 2541
Query: 490 RSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPS----RSPSPKKPLSRDKDGEGRARHSEA 545
S S SSS S S S P P R PSP P ++ EGR
Sbjct: 2542 SSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT-PAPKEAVREGRP----P 2596
Query: 546 EATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTR 605
E T A+R+ RS S S S +S SSSSS SS S+
Sbjct: 2597 EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSS-------------SSSSSSSSSSSSSS 2643
Query: 606 SHSRSPSPGHSH---------------GSYSSRS--------HGTRSRT------RSPSR 636
S S SPSP G SRS +RS + R PS
Sbjct: 2644 SSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSP 2703
Query: 637 TPSPSYHSRSSSESG 651
PSP SSSE G
Sbjct: 2704 QPSPRDQQSSSSERG 2718
Score = 60.1 bits (144), Expect = 6e-09
Identities = 67/257 (26%), Positives = 86/257 (33%), Gaps = 22/257 (8%)
Query: 188 ESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTES 247
E S G+ P K RR S S S S SS S
Sbjct: 2508 EPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSS 2567
Query: 248 -PGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGS 306
P + S +P+ + R P K + +RSS S S S S S
Sbjct: 2568 LPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRK--------RRSSSSSSSSSSSSS 2619
Query: 307 GWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSP 366
S + S S + S+ S P+ P P+ K A+ PP + S SP
Sbjct: 2620 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGE-RRSRSP 2678
Query: 367 RSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRA 426
R P R R+ + RRR + R S+ RG RR + RG SRS S
Sbjct: 2679 RK-PIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQ----RGDSRSPSHK 2733
Query: 427 RSSSDSGSGRGAPGPGP 443
R R P P P
Sbjct: 2734 RR-------RETPSPRP 2743
Score = 57.4 bits (137), Expect = 4e-08
Identities = 114/466 (24%), Positives = 159/466 (34%), Gaps = 78/466 (16%)
Query: 160 SSSSASPPPKKKKK--KKGGHRRSRKKRRLESECSC--GSSSPLRKKKKSVKKHRRD--R 213
S SS+SPPPK+K K + H S +++S GS + + ++SV RR
Sbjct: 815 SRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFE 874
Query: 214 SDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGR--------------RSHRHSSGS 259
S K R SR S + P +SP R R HS S
Sbjct: 875 SSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSS 934
Query: 260 SHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQ 319
S SPS + + R +SP E R SGS SP +P R SG
Sbjct: 935 SPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKP--ETPPRQSHSGS 992
Query: 320 RSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSS---QGRG 376
SP P+V+ A P P G +SP P+ Q
Sbjct: 993 -------------------ISPYPKVK---AQTPPGPSLSGSKSPCPQEKSKDSLVQSCP 1030
Query: 377 GRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGR 436
G + AG + +S P +G S++ RS + S R
Sbjct: 1031 GSLSLCAGVK-------------SSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVR 1077
Query: 437 GAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHP 496
+ P S+ G R++ P AS SP G S SP
Sbjct: 1078 QSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRG--------EFSASP---- 1125
Query: 497 RSWSSSRSPSKSRSRS-AEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSR 555
S SP +SR +S + P S S + L + E A + +AT + R +
Sbjct: 1126 -MLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQK 1184
Query: 556 ---SYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCL 598
S P++ R S F + R T R+R P +S L
Sbjct: 1185 DKFSPFPVQDRPESSLVFKDTLR-TPPRERSGAGSSPETKEQNSAL 1229
Score = 43.9 bits (102), Expect = 5e-04
Identities = 123/547 (22%), Positives = 189/547 (34%), Gaps = 64/547 (11%)
Query: 156 TKHWSSSSASPPPKKKKKKKGG---HRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRD 212
T+ S S SP +++ + + RRSR + L S SPL ++++ R
Sbjct: 2002 TRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPL-----AIRRRSRS 2056
Query: 213 RSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSP-SLSSHYSD 271
R+ +R K R +RS R+ + S + R+ SGS P +L+S
Sbjct: 2057 RTPRTARGK-RSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMS 2115
Query: 272 SRSPSRLSPKHRDEGRKTGSQRSSG-SRSP----SPSGGSGWGSPQRNGGSGQRSGAHGG 326
S +SP D R G G SR+P +GGS P QR+
Sbjct: 2116 CFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPEN 2175
Query: 327 RP-------------GSAHSPPDKPSSPSPRVRDKAAAAAP-----TPPARGKESPSPRS 368
G+A PP ++ + A P T PA S P +
Sbjct: 2176 HAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAA 2235
Query: 369 APSSQGRGG-------RAAGGAGRR--RRRRRRRRRSRSSASAPRRRGRRRPR----PAP 415
+ ++ A A R S +A AP PR PA
Sbjct: 2236 SAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAV 2295
Query: 416 PRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPG 475
+R+ + + S +GSG P P S R P A +T+P
Sbjct: 2296 NLAGARTPAALAALSLTGSGT-PPTAANYPSSSRTPQAPASANLVGPRSAH--ATAPVNI 2352
Query: 476 AHGRRG---GPEGKSSSR-SPGPHPRSWSSSRSPSKSRSR-SAEKRPHSPSRSPSPKKPL 530
A R P +S+R +P + +S R P + R S P R+ S P
Sbjct: 2353 AGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPS 2412
Query: 531 SRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSP---SFMEPRRITSARKRPIPYY 587
+ + R + + S+S P + + SP +F + R A+ P+
Sbjct: 2413 APSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPV--- 2469
Query: 588 RPSPSSSSSCLSSDYSTRSHSRS----PSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYH 643
S S SS +++ S+ P+PG H T ++ S P+
Sbjct: 2470 AGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKE 2529
Query: 644 SRSSSES 650
RSSS S
Sbjct: 2530 RRSSSSS 2536
Score = 37.7 bits (86), Expect = 0.034
Identities = 45/194 (23%), Positives = 65/194 (33%), Gaps = 24/194 (12%)
Query: 163 SASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKR 222
S +P PK+ ++ + KR+ S S SSS S S S
Sbjct: 2581 SPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSS------------SSSSSSSSSSSSS 2628
Query: 223 RHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKH 282
S SS + P PG ++ + P SRSP +
Sbjct: 2629 SSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERR---SRSPRKPIDSL 2685
Query: 283 RDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDK--PSS 340
RD + S SP P SP+ S G+ G+ G + SP K +
Sbjct: 2686 RDSRSLSYSPVERRRPSPQP-------SPRDQQSSSSERGSRRGQRGDSRSPSHKRRRET 2738
Query: 341 PSPRVRDKAAAAAP 354
PSPR ++ +P
Sbjct: 2739 PSPRPMRHRSSRSP 2752
Score = 36.6 bits (83), Expect = 0.075
Identities = 44/156 (28%), Positives = 51/156 (32%), Gaps = 13/156 (8%)
Query: 152 RGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKK---KKSVKK 208
R R+ SSSS+S S S S SSSP K + K
Sbjct: 2603 RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKP 2662
Query: 209 HRRDRSDSGSRRKRRHRSRSSKCKRKEKNK----EKKRPHTESPGRRSHRHSSGSSHSPS 264
+ G RR R R + E++RP SP S SS S
Sbjct: 2663 ASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRP---SPQPSPRDQQSSSSERGS 2719
Query: 265 LSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSP 300
DSRSPS K R E R SRSP
Sbjct: 2720 RRGQRGDSRSPSH---KRRRETPSPRPMRHRSSRSP 2752
>gi|50083281 KIAA1853 protein [Homo sapiens]
Length = 611
Score = 210 bits (534), Expect = 4e-54
Identities = 196/538 (36%), Positives = 247/538 (45%), Gaps = 79/538 (14%)
Query: 152 RGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKK-SVKKHR 210
RG+ H + P + KKKKK + +RKKRR S S SP++KKKK S KKH+
Sbjct: 90 RGHSASHDKDLTPPPSSRGKKKKK---KSTRKKRRRSSSYS---PSPVKKKKKKSSKKHK 143
Query: 211 RDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYS 270
R RS S +KRRH S S K KR+++ + KK+ + S R+SHRH S S SS
Sbjct: 144 RRRSFS---KKRRHSSSSPKSKRRDEKRHKKQ--SRSRPRKSHRHRHHRCPSRSQSSESR 198
Query: 271 DSRSPSR---LSPKHRDEGRKTGSQRSSGSR---SPSPSGGSGWGSPQRNGGSGQRSGAH 324
S SR SP+ + R+ S+R S + SP P + G G
Sbjct: 199 PSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVI 258
Query: 325 GGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRG-----GRA 379
G GSA K +SP R ++ G ++ SP S +S R G
Sbjct: 259 TGS-GSAADLFTKTASPLTTSRGRSQEYDS-----GNDTSSPPSTQTSSARSRGQEKGSP 312
Query: 380 AGGAGRRRRRRRRRRRSRSSA---SAPRRRGRRRPRPAPP-------------------R 417
+GG + R ++ S+P+ +G +P +
Sbjct: 313 SGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVK 372
Query: 418 GSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAH 477
SS S ARSS G R + S H + P + STS ++
Sbjct: 373 KSSLVPSTARSSPMKGCSRSSSYASTRSSS---HSSRSPNPRASPRYTQSRSTSSEKRSY 429
Query: 478 GRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGE 537
R KS RSP RS S RSPS SR +SPSR PK +KD +
Sbjct: 430 SRSPSYSSKSGKRSPPS--RSSRSRRSPSYSR--------YSPSRERDPKYS---EKDSQ 476
Query: 538 GRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSC 597
R R RARRR RSYSP+RKRRRDSPS +E RRITSARKRPIPYYRPSPSSS S
Sbjct: 477 QRERE------RARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSL 530
Query: 598 LS-SDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTR----SPSRTPSPSYHSRSSSES 650
S S + + S SRS S +S SRS RSRTR S SR+PSP SRS S S
Sbjct: 531 SSTSSWYSSSSSRSASRSYSRSRSRSRSR-RRSRTRTSSSSSSRSPSPGSRSRSRSRS 587
Score = 97.8 bits (242), Expect = 3e-20
Identities = 127/483 (26%), Positives = 194/483 (40%), Gaps = 62/483 (12%)
Query: 148 YRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLES------ECSCGSSSPLRK 201
++ R + K SSS+ PK K++ + H++ + R +S C S S +
Sbjct: 142 HKRRRSFSKKRRHSSSS---PKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESR 198
Query: 202 KKKSVKKHRRDRSDSGSRRKRRHRSRSSK--CKRKEKNKEKKRPH--TESPGRRSHRH-S 256
+HR + G + +RRH R SK CK + + + P + G S R
Sbjct: 199 PSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVI 258
Query: 257 SGSSHSPSLSSHYSDSRSPSRLSPKHRDEGR--------KTGSQRSSGSRSPSPSGGSGW 308
+GS + L + + + SR + D G +T S RS G SPSGG
Sbjct: 259 TGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGL-- 316
Query: 309 GSPQRNGGSGQRSGAHGGRPGSAHSPPDKPS-----SPSPRVRDKAAAAAP--------- 354
S R SG S + G + SP +K + SP+ R R+ +P
Sbjct: 317 -SKSRELNSGNTSDS--GNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKK 373
Query: 355 --TPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPR 412
P+ + SP + SS R++ + R R R ++S +++ +R R
Sbjct: 374 SSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSR-- 431
Query: 413 PAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERP-PRARPASTS 471
P SS+S R+ S S S R P ER K +++R RAR S
Sbjct: 432 --SPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRS 489
Query: 472 PSPGAHGRRGGPEG------KSSSRSPGPHPR-------SWSSSRSPSKSRSRSAEKRPH 518
SP RR P S+ + P P+ R S SS+ S S S + R +
Sbjct: 490 YSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSY 549
Query: 519 SPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITS 578
S SRS S + SR + + S + +R+R RSRS S R R + S S+ +S
Sbjct: 550 SRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQ-SRSYSSADSYSS 608
Query: 579 ARK 581
R+
Sbjct: 609 TRR 611
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 134 bits (336), Expect = 3e-31
Identities = 149/521 (28%), Positives = 200/521 (38%), Gaps = 80/521 (15%)
Query: 166 PPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLR-------KKKKSVKKHRRDRSDSGS 218
PPP+ ++ + RR R L S SSS R K+ S + R S S S
Sbjct: 334 PPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSAS 393
Query: 219 RRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSR--SPS 276
+RRHR S K + P + R+S S S ++ H + SPS
Sbjct: 394 PPRRRHRP-SPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPS 452
Query: 277 --------RLSPKHRDEGRKTGSQ---------RSSGSRSPSPSGGSGWGSPQRNGGSGQ 319
LS D+G K + R +S S SG S +R S
Sbjct: 453 PAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHV 512
Query: 320 RSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRA 379
++G G R HSP + +SPSPR R K + P R + SPSP P ++ R +
Sbjct: 513 KNGEVGRR--RRHSP-SRSASPSPRKRQKETS----PRGRRRRSPSP---PPTRRRRSPS 562
Query: 380 AGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAP 439
RRRR R R+ + PRRR R +PP + R S S R A
Sbjct: 563 PAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPP------IQRRYSPSPPPKRRTAS 616
Query: 440 GPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHG----RRGGPEGKSSSRSPGPH 495
P P +RA PP R S SP P +R P S R
Sbjct: 617 PPPPPK----------RRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSP 666
Query: 496 PRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRR-S 554
RS +RSP ++ S RP +P S SP P+ R + R S + +TR RR S
Sbjct: 667 SRSTREARSPQPNKRHSPSPRPRAPQTSSSPP-PVRRGASSSPQRRQSPSPSTRPIRRVS 725
Query: 555 RSYSPIRKRRRDSPSFMEPRRITSARK---RPIPYYRPSPSSSSSCLSSDYSTRSHSRSP 611
R+ P + ++ SPS RR++S+R P P + P+ S S ST P
Sbjct: 726 RTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVP 785
Query: 612 SPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESGG 652
+ +SP TPSPS S E GG
Sbjct: 786 V----------------KKAKSP--TPSPSPPRNSDQEGGG 808
Score = 126 bits (317), Expect = 5e-29
Identities = 175/618 (28%), Positives = 236/618 (38%), Gaps = 77/618 (12%)
Query: 63 VELKCMELQEMMEEQGYSEEEIRQKVGTFRQMLMEKEGVLTREDRPGGHIVAETPRLTEG 122
+ELK E+++ EQ +Q ++ EKE + +R + +PR +
Sbjct: 124 LELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRER------SRSPRRRKS 177
Query: 123 AEPGLEYAPFDDDDGPVDCDCPASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSR 182
P PV + S R R +RTK S S SP P+KK+K S
Sbjct: 178 RSPSPRRR-----SSPVRRERKRSHSRSPR-HRTK---SRSPSPAPEKKEKTPELPEPSV 228
Query: 183 KKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKR 242
K + + + +S L+ K ++ S K +KEK KEK R
Sbjct: 229 KVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPE-------------KNSKKEKEKEKTR 275
Query: 243 PHTESPGR-RSHRHSSGSSHSPSLSSHYSDSRSPS---RLSPKHRDEGRKTGSQRSSGSR 298
P + S + RS S SH+ H S SRS S R SP+ R R+ R+ R
Sbjct: 276 PRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRR----RTPPRR 331
Query: 299 SPSPSGGSGWGSP--QRNGGSGQRSGAHGGRPGS-AHSPPDKP----SSPSPRVRDKAAA 351
P P SP +R S SG+ S + SPP KP SSP + R + +
Sbjct: 332 MPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPS 391
Query: 352 AAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRP 411
A+P R + PSP + P + R + R R+ R R+S + +G +
Sbjct: 392 ASPP---RRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKR 448
Query: 412 RPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPE--------PGSERGHGGHGKRAKERPP 463
P R + + S D G A + S G ERP
Sbjct: 449 ESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPK 508
Query: 464 RARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRS 523
R+ + G GRR S SRS P PR SP R RS P RS
Sbjct: 509 RSHVKN-----GEVGRR---RRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRS 560
Query: 524 PSPKKPLSRDKDGEGRARHSEAEATRARRRS---RSYSPIRKRRRDSPSFMEPRRITSAR 580
PSP P R + R + RRRS R YSP +RR SPS RR +A
Sbjct: 561 PSPAPPPRRRRTPTPPPRR-RTPSPPPRRRSPSPRRYSPPIQRRY-SPSPPPKRR--TAS 616
Query: 581 KRPIPYYRPSPS-------SSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTR-SRTR 632
P P R SPS S S S + RSPS H SS S TR +R+
Sbjct: 617 PPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSP 676
Query: 633 SPSRTPSPSYHSRSSSES 650
P++ SPS R+ S
Sbjct: 677 QPNKRHSPSPRPRAPQTS 694
Score = 126 bits (317), Expect = 5e-29
Identities = 149/524 (28%), Positives = 204/524 (38%), Gaps = 107/524 (20%)
Query: 166 PPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHR 225
P P+K KK+ ++R + R S+ + R RS S +R +RRHR
Sbjct: 259 PSPEKNSKKEKEKEKTRPRSRSRSKS---------------RSRTRSRSPSHTRPRRRHR 303
Query: 226 SRSSKCKRKEKNKEKKRP------------------HTESPGRRSHRHSSGSSHSPSLSS 267
SRS + + ++RP + SP RR R SS S S SS
Sbjct: 304 SRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRR-RRRSSASLSGSSSSS 362
Query: 268 HYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGR 327
S SRSP + PK R + R + SPS S P+R R
Sbjct: 363 SSSRSRSPPKKPPK-----RTSSPPRKTRRLSPSAS------PPRRR-----------HR 400
Query: 328 PGSAHSPPDKP-SSPSP----RVRDKAAAAAPTPPA---------RGKESPSPRSAP--- 370
P +PP K SP+P R R + +P + +ESPSP P
Sbjct: 401 PSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKV 460
Query: 371 ----SSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRA 426
S + +GG+ A ++RR+ RR+ +SS+ + RP + + R
Sbjct: 461 ELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRR 520
Query: 427 RSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGK 486
R S S S +P + S R G +R+ PP R S SP+P RR P
Sbjct: 521 RRHSPSRSASPSPRKRQKETSPR---GRRRRSPSPPPTRRRRSPSPAPPPR-RRRTPTPP 576
Query: 487 SSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPS-----RSPSPKKPLSRDKDGEGRAR 541
R+P P PR RSPS R +R +SPS R+ SP P R +
Sbjct: 577 PRRRTPSPPPR----RRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPK 632
Query: 542 HSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSD 601
+ + ++RS SP+ KRR SPS R S SPS S+ S
Sbjct: 633 RRVSHSPPPKQRS---SPVTKRR--SPSLSSKHRKGS-----------SPSRSTREARSP 676
Query: 602 YSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSR 645
+ HS SP P S SS R + SP R SPS +R
Sbjct: 677 QPNKRHSPSPRPRAPQTS-SSPPPVRRGASSSPQRRQSPSPSTR 719
Score = 108 bits (270), Expect = 2e-23
Identities = 128/491 (26%), Positives = 178/491 (36%), Gaps = 52/491 (10%)
Query: 194 GSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSH 253
G S + KK K R+ + + K++ + + K ++++ +KR + SP RR
Sbjct: 118 GIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKS 177
Query: 254 RHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPS-PSGGSGWGSPQ 312
R S S S RS SR SP+HR + R ++P P P
Sbjct: 178 R--SPSPRRRSSPVRRERKRSHSR-SPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPS 234
Query: 313 RNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSS 372
+ +P P +P PSP K + KE PRS S
Sbjct: 235 VQEATSTSDILKVPKP----EPIPEPKEPSPEKNSK--------KEKEKEKTRPRSRSRS 282
Query: 373 QGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRP---APP------------- 416
+ R + R RRR R RSRS + R RRRP P PP
Sbjct: 283 KSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSR 342
Query: 417 ------RGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPAST 470
R SS SLS + SSS S R P P+ S PPR R +
Sbjct: 343 SPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPS 402
Query: 471 SPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPL 530
P+ R P + S+R+ S S R+ K ++ SPS +P P+K
Sbjct: 403 PPATPPPKTRHSPTPQQSNRTRKSRV-SVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVE 461
Query: 531 SRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRR---------ITSARK 581
+ + + + + A++ + RR+ R + S S E R R+
Sbjct: 462 LSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRR 521
Query: 582 RPIPYYRPSPS-SSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSP---SRT 637
R P SPS +S R S SP P S S R RT +P RT
Sbjct: 522 RHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRT 581
Query: 638 PSPSYHSRSSS 648
PSP RS S
Sbjct: 582 PSPPPRRRSPS 592
Score = 103 bits (258), Expect = 4e-22
Identities = 123/516 (23%), Positives = 191/516 (37%), Gaps = 84/516 (16%)
Query: 155 RTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRS 214
R +H S A+PPPK + +K R+ S SP R K K ++
Sbjct: 396 RRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRV-------SVSPGRTSGKVTKHKGTEKR 448
Query: 215 DSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTES-PGRRSHRHSSGSSHSPSLSSHYSDSR 273
+S S + R + E++K K +S RR +R + S S S SS S+
Sbjct: 449 ESPSPAPK---PRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDE 505
Query: 274 SPSRLSPKHRDEGRKTGSQRSSGSRSPSPSG----------GSGWGSPQRNGGSGQRSGA 323
P R K+ + GR+ +R S SRS SPS G SP +RS +
Sbjct: 506 RPKRSHVKNGEVGRR---RRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPS 562
Query: 324 HGGRPGSAH-----------SPPDKPSSPSPR---------------VRDKAAAAAPTPP 357
P SPP + SPSPR + + A+ P P
Sbjct: 563 PAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPK 622
Query: 358 ARGKESPSPRSAPSSQGRGGRAAGGAGRRR------RRRRRRRRSRSSASA----PRRRG 407
R SP P+ S + + +RR + R+ SRS+ A P +R
Sbjct: 623 RRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRH 682
Query: 408 RRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARP 467
PRP P+ SS R +S S R +P P P R R P +
Sbjct: 683 SPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRP----------IRRVSRTPEPKK 732
Query: 468 ASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSP---SRSP 524
+ SP R +S S SP P + + SP +S+S S P P ++SP
Sbjct: 733 IKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSP 792
Query: 525 SPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRD-----------SPSFMEP 573
+P R+ D EG + + + + ++ + + +K +++ +P+ +
Sbjct: 793 TPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAA 852
Query: 574 RRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSR 609
T A++ P+ P + S + H R
Sbjct: 853 ATTTLAQEEPVAAPEPKKETESEAEDNLDDLEKHLR 888
Score = 86.7 bits (213), Expect = 6e-17
Identities = 107/399 (26%), Positives = 143/399 (35%), Gaps = 103/399 (25%)
Query: 150 GHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKH 209
G G R +H S SASP P+K++K+ R R++ S
Sbjct: 515 GEVGRRRRHSPSRSASPSPRKRQKETSPRGR-------------------RRRSPSPPPT 555
Query: 210 RRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHY 269
RR RS S + RR R+ + +R+ T SP R R S +SP + Y
Sbjct: 556 RRRRSPSPAPPPRRRRTPTPPPRRR----------TPSPPPR-RRSPSPRRYSPPIQRRY 604
Query: 270 SDSRSPSRLS----------------PKHRDEGRKTGSQRSS---GSRSPSPSGGSGWGS 310
S S P R + PK R QRSS RSPS S S
Sbjct: 605 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLS------S 658
Query: 311 PQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAP 370
R G S RS P P+K SPSPR R +++P PP R S SP
Sbjct: 659 KHRKGSSPSRSTREARSP-----QPNKRHSPSPRPRAPQTSSSP-PPVRRGASSSP---- 708
Query: 371 SSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAP-PRGSSRSLSRARSS 429
+RR+S S ++ P RR R P P + +S S R
Sbjct: 709 ---------------------QRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRV 747
Query: 430 SDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSS 489
S S S G+P P A ++PP S SP + P K+ S
Sbjct: 748 SSSRSVSGSPEP----------------AAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKS 791
Query: 490 RSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKK 528
+P P P S K + + +K+ + KK
Sbjct: 792 PTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKK 830
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 120 bits (300), Expect = 5e-27
Identities = 148/521 (28%), Positives = 204/521 (39%), Gaps = 55/521 (10%)
Query: 160 SSSSASPPPKKKKKKKGGHR-RSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGS 218
S S+ S K+ + R R R K R S S + + K V+ H+R + S
Sbjct: 62 SKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRG 121
Query: 219 RRKRRHRSRSSKCKRKEKNKEKKRPHTESPGR-RSHRHSSG-SSHSPSLSSHYSDSRSPS 276
R R SRSSK + +PGR R+H G +S + +S SR S
Sbjct: 122 RTPGRRGSRSSK---------RSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKS 172
Query: 277 RLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPD 336
P+ + R R+ +S P GGSG G + + + D
Sbjct: 173 YGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSD 232
Query: 337 KPSSPSPR---------VRDKAAAAAPTPPA---RGKESPSPRSAPSSQGRG---GRAAG 381
PS S R + + + +PT + + S RS P S + R+
Sbjct: 233 NPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRS 292
Query: 382 GAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGS-SRSLSRARSSSDSGSGRGAPG 440
G+ +R R R + + S R R R+ R S SRS S+ +S + S + R
Sbjct: 293 GSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRS 352
Query: 441 P--GPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGK----SSSRSPGP 494
P ER H +KER R S+SP + + G K S SRSP
Sbjct: 353 HNWSRNPSKERSHSHSRSSSKERDHR---GSSSPRKESGRSQSGSPNKQRDHSRSRSPN- 408
Query: 495 HPRSWSSSRSPSKSRSRSAEKRPH-----SPSRSPSPKKPLSRDKDGEGRARHSEAEA-T 548
R S SRSP K+R RS + P+ S SRSP + SR + HS + +
Sbjct: 409 KARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPN 468
Query: 549 RARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYST--RS 606
+AR RSRS SP + RD P + R+ SPS C S S+ R
Sbjct: 469 KARDRSRSRSP--SKERDHSQLGSPSKERDHRR------SRSPSKERQCRQSRSSSKERD 520
Query: 607 HSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSS 647
H RS SP SRS + R RS SR+PS R S
Sbjct: 521 HRRSRSPSKERQRRQSRS-PNKERDRSQSRSPSEEREHRQS 560
Score = 119 bits (298), Expect = 9e-27
Identities = 146/506 (28%), Positives = 202/506 (39%), Gaps = 70/506 (13%)
Query: 163 SASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKK-HRRDRSDSGSRRK 221
S SP + K +R + + S+ S SP R + S K+ H R RS S R
Sbjct: 256 SYSPTEMSSRVKSYNQASTRSRPQSHSQ----SRSPRRSRSGSQKRTHSRVRSHSWKRNH 311
Query: 222 RRHRSRSSKCKRKEKNKEKK-RPHTESPGRRSHRHSS-GSSHSPSLSSHYSDSRSPSRLS 279
R RSR+ K + + + R H++ + R G SH+ S + S S SR S
Sbjct: 312 SRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSS 371
Query: 280 PKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPS 339
K RD R + S R RS S GSP + QR + P A D+
Sbjct: 372 SKERDH-RGSSSPRKESGRSQS-------GSPNK-----QRDHSRSRSPNKAR---DRSR 415
Query: 340 SPSP-RVRDKAAAAAPTPPARGKESPSPRSAPS-SQGRGGRAAGGAGRRRRRRRRRRRSR 397
S SP + RD++ + +P S SP A S+ R A R R + R RSR
Sbjct: 416 SRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSR 475
Query: 398 SSASAPRRRGRRRPRPAPPRGSSRSLS--------RARSSSDSGSGRGAPGPGPEPGSER 449
S + + R + P+ R RS S ++RSSS R + P E
Sbjct: 476 SRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKER---- 531
Query: 450 GHGGHGKRAKERPP---RARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPS 506
+R + R P R R S SPS R+ K R R W RSPS
Sbjct: 532 ------QRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDR------RRW---RSPS 576
Query: 507 KSRSR-----SAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIR 561
K R R S+E+R HS SRSP+ + G R R S E +R R+ S
Sbjct: 577 KERERRQSRSSSEERDHSRSRSPNKQS-------GYSRPRASSKEKAHSRSRTPSKEGNH 629
Query: 562 KRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYS 621
+ R S +P + T R P ++ SP+ +SS + +++ S SPS S G
Sbjct: 630 SQSRTSSKESDPSQSTVPRS---PDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTL 686
Query: 622 SRSHGTRSRTRSPSRTPSPSYHSRSS 647
S+ T S + P S SS
Sbjct: 687 SQDDSQADATTSKATLPGERSSSSSS 712
Score = 81.6 bits (200), Expect = 2e-15
Identities = 95/389 (24%), Positives = 145/389 (37%), Gaps = 24/389 (6%)
Query: 149 RGHRGYRTKHWS---SSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKS 205
R R R+ +WS S S + K+ HR S R+ GS + R +S
Sbjct: 345 RTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRS 404
Query: 206 VKKHR-RDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPS 264
++ RDRS S S K R RSRS + + P+ RS + HS S
Sbjct: 405 RSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRS 464
Query: 265 LSSHYSDSRSPSRLSPKHRDEGRK-TGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGA 323
S + + RS SR K RD + + S+ RS SPS R S +
Sbjct: 465 RSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQC----RQSRSSSKERD 520
Query: 324 HGGRPGSAHSPPDKPSSPSP-RVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGG 382
H R S + S SP + RD++ + +P+ ++S SP S+ R R
Sbjct: 521 HR-RSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSP-----SKERDRRRWRS 574
Query: 383 AGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPG 442
+ R RR+ R S + R ++ + PR SS+ + +RS + S G +
Sbjct: 575 PSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHS---- 630
Query: 443 PEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSS 502
R ++ PR+ SP+ + + K+SS SP P +
Sbjct: 631 ----QSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTL 686
Query: 503 RSPSKSRSRSAEKRPHSPSRSPSPKKPLS 531
+ K RS S L+
Sbjct: 687 SQDDSQADATTSKATLPGERSSSSSSKLA 715
Score = 72.0 bits (175), Expect = 2e-12
Identities = 109/403 (27%), Positives = 156/403 (38%), Gaps = 47/403 (11%)
Query: 262 SPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRS 321
SP SS S S +PS S D + S +S+ S +P+ S + RN S
Sbjct: 3 SPKRSSKPSMSLAPSGSSMPTADP-KPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSS 61
Query: 322 GAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAG 381
+ +P ++PSS S RVR KA +PS S + + +A+
Sbjct: 62 SKSTKSTSTKRAPSNRPSSRS-RVRSKA------------RTPSRVSTDTRTSKASKASD 108
Query: 382 GAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGP 441
R +RR + S P RRG R + +P R S+ R + + R
Sbjct: 109 V------RCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPT 162
Query: 442 GPEPGSE-----RGHGGHGKRAKERPPRARPASTSPSPGAHGRRGG-----PEGKSSSRS 491
+ GS R + +R+ +P S P G+ R P
Sbjct: 163 SQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTP 222
Query: 492 PGPHPRSWSSSRSPSKSRSRSAEKRPHSPSR--SPSPKKPLSRDK---DGEGRARHSEAE 546
G + S + SPS SR + + PSR S SP + SR K R+R
Sbjct: 223 TGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHS 282
Query: 547 ATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRS 606
+R+ RRSRS S R R S R + AR R + S + +RS
Sbjct: 283 QSRSPRRSRSGSQKRTHSR-VRSHSWKRNHSRARSR-------TRKGILSQMGRHSQSRS 334
Query: 607 HSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSE 649
HS+ S S RSH + +R+PS+ S S HSRSSS+
Sbjct: 335 HSKGKSQNQSRTPRRGRSH---NWSRNPSKERSHS-HSRSSSK 373
Score = 65.9 bits (159), Expect = 1e-10
Identities = 70/253 (27%), Positives = 103/253 (40%), Gaps = 26/253 (10%)
Query: 147 CYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSV 206
C R Y+ + S S SP + + ++R + R S S L K
Sbjct: 437 CSRSRSPYKARD-RSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKE- 494
Query: 207 KKHRRDRSDSGSRRKRRHRSRSSK---CKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSP 263
+ HRR RS S R+ R+ RS S + + + +KE++R + SP + R S SP
Sbjct: 495 RDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDR---SQSRSP 551
Query: 264 SLSSHYSDSRSPSR-------LSPKHRDEGR--KTGSQRSSGSRSPSPSGGSGWGSPQRN 314
S + SRSPS+ SP E R ++ S+ SRS SP+ SG+ P+ +
Sbjct: 552 SEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRAS 611
Query: 315 GGSGQRSGAHGGRPGSAHS---PPDKPSSPS----PRVRDKAAAAAPTPPARGKESPSPR 367
S + HS K S PS PR D + T +PS
Sbjct: 612 SKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKT 671
Query: 368 S--APSSQGRGGR 378
S +PS+ GG+
Sbjct: 672 SSHSPSTFPSGGQ 684
Score = 29.6 bits (65), Expect = 9.1
Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 4/83 (4%)
Query: 568 PSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGT 627
P+ ++ + + + +P + +S SS ST+S S +P + SSRS
Sbjct: 29 PASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRP---SSRSR-V 84
Query: 628 RSRTRSPSRTPSPSYHSRSSSES 650
RS+ R+PSR + + S++S S
Sbjct: 85 RSKARTPSRVSTDTRTSKASKAS 107
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 98.6 bits (244), Expect = 2e-20
Identities = 105/358 (29%), Positives = 146/358 (40%), Gaps = 39/358 (10%)
Query: 207 KKHRRDRSDSGSRRKRRH-RSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSL 265
+K R GSRR+R + RSRS R +K + SH S S S S
Sbjct: 168 RKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSR 227
Query: 266 SSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHG 325
S S SRS SR R + K+ S SRS S S G + ++ +
Sbjct: 228 SRSKSRSRSQSR----SRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNV 283
Query: 326 GRP----GSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAG 381
G+P S H K S S R + R +E +S S+ +GG
Sbjct: 284 GKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGG---- 339
Query: 382 GAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGP 441
R R RSRS S +R+GR+R R SRS SR+RS S+ R
Sbjct: 340 --------SRSRSRSRSK-SKDKRKGRKRSRE-----ESRSRSRSRSKSERSRKR----- 380
Query: 442 GPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSR-SPGPHPRSWS 500
GS+R + K++ R S SPS R + +SS R G + +
Sbjct: 381 ----GSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGT 436
Query: 501 SSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYS 558
+ + S+SRS S K P+ PS S S K S+ + ++R A + +R RSRS+S
Sbjct: 437 NQETRSRSRSNSKSK-PNLPSESRSRSKSASKTR-SRSKSRSRSASRSPSRSRSRSHS 492
Score = 87.8 bits (216), Expect = 3e-17
Identities = 84/282 (29%), Positives = 112/282 (39%), Gaps = 20/282 (7%)
Query: 376 GGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSG 435
G R R R R R RSR S + R G + + R SRS SR+RS S S S
Sbjct: 178 GSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQ 237
Query: 436 -------RGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSS 488
+ P E R H R+K + + + G K
Sbjct: 238 SRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVG----------KPK 287
Query: 489 SRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEAT 548
SRSP H +S S SRS S+ R EKR S SR S +K L R R++ +
Sbjct: 288 SRSPSRH-KSKSKSRSRSQERRVEEEKRG-SVSRGRSQEKSL-RQSRSRSRSKGGSRSRS 344
Query: 549 RARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHS 608
R+R +S+ RKR R+ R S R R R S + SS + + RS S
Sbjct: 345 RSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQS 404
Query: 609 RSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSES 650
RSPS S ++S ++ R S + +RS S S
Sbjct: 405 RSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRS 446
Score = 82.8 bits (203), Expect = 9e-16
Identities = 103/392 (26%), Positives = 152/392 (38%), Gaps = 63/392 (16%)
Query: 235 EKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRS 294
E N K R + PG R R S S S +S SRS SR S K R ++GS +S
Sbjct: 164 EVNGRKIRLVEDKPGSRRRR-------SYSRSRSHSRSRSRSRHSRKSRS---RSGSSKS 213
Query: 295 SGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAP 354
S S+S S S GS RS + + S +K SPS + +A
Sbjct: 214 SHSKSRSRS----------RSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAG 263
Query: 355 TPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPA 414
++ K+ + + G + R R + +S+S + + RR R +
Sbjct: 264 KSRSKSKDQAEEKIQNNDNV-------GKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGS 316
Query: 415 PPRGSS--RSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSP 472
RG S +SL ++RS S R GG R+ R+R S
Sbjct: 317 VSRGRSQEKSLRQSRSRS------------------RSKGGSRSRS-----RSRSKSKDK 353
Query: 473 SPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSR 532
G R +S SRS R S R S+ +K S+S SP + +S+
Sbjct: 354 RKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSK 413
Query: 533 DKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPS 592
+++ H+++E+++ R S + + S S R S K +P S S
Sbjct: 414 ERE------HAKSESSQREGRGESENAGTNQETRSRS-----RSNSKSKPNLPSESRSRS 462
Query: 593 SSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRS 624
S+S S +RS S S SP S SRS
Sbjct: 463 KSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 82.0 bits (201), Expect = 2e-15
Identities = 89/325 (27%), Positives = 127/325 (39%), Gaps = 37/325 (11%)
Query: 142 DCPASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRK 201
D P S R H S S S +K + + G + S K R S S S R
Sbjct: 175 DKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRS 234
Query: 202 KKKSVKKHRRDRSDSGSRRKRRHRSRS---SKCKRKEKNKEK-------KRPHTESPGRR 251
+ +S + ++++S S S+ K R RS S S+ K K++ +EK +P + SP R
Sbjct: 235 RSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRH 294
Query: 252 SHRHSSGSSHSP-----SLSSHYSDSRSPSRLSPKHRDEGRKTGSQRS-SGSRSPSPSGG 305
+ S S S RS + + R R G RS S SRS S
Sbjct: 295 KSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKR 354
Query: 306 SGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVR----DKAAAAAPTPPARGK 361
G + S RS + R S D + S + + D++ + +P+ +
Sbjct: 355 KGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKE 414
Query: 362 ESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRR-----------RSRS-SASAPRRRGRR 409
+ + +GRG G + R R R RSRS SAS R R +
Sbjct: 415 REHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKS 474
Query: 410 RPRPAPPRGSSRSLSRARSSSDSGS 434
R R A SRS SR+RS S S S
Sbjct: 475 RSRSA-----SRSPSRSRSRSHSRS 494
Score = 79.7 bits (195), Expect = 8e-15
Identities = 93/333 (27%), Positives = 135/333 (40%), Gaps = 38/333 (11%)
Query: 345 VRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPR 404
V DK + +R + RS S R R+ G+ + + R R S S +
Sbjct: 173 VEDKPGSRRRRSYSRSRSHSRSRSR-SRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSK 231
Query: 405 RRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSER--GHGGHGKRAKERP 462
R R + R + SRS S+ +S S S S + + E+ + GK P
Sbjct: 232 SRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSP 291
Query: 463 PRARPASTSPSPGAHGR-----RG----GPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSA 513
R + S S S R RG G + S R RS SRS S+SRS+S
Sbjct: 292 SRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSK 351
Query: 514 EKRP-HSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFME 572
+KR SR S + SR K R R S+ ++ + + + + SPS
Sbjct: 352 DKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPS--- 408
Query: 573 PRRITSARKRPIPYYRPSPSSS------SSCLSSDYSTRSHSRS--------PSPGHSHG 618
R ++ R+ + S SS S ++ TRS SRS PS S
Sbjct: 409 -RSVSKERE-----HAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRS 462
Query: 619 SYSSRSHG-TRSRTRSPSRTPSPSYHSRSSSES 650
+S++ ++SR+RS SR+PS S SRS S S
Sbjct: 463 KSASKTRSRSKSRSRSASRSPSRS-RSRSHSRS 494
Score = 35.8 bits (81), Expect = 0.13
Identities = 41/123 (33%), Positives = 47/123 (38%), Gaps = 31/123 (25%)
Query: 530 LSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRP 589
L DK G R R + RSRS+S R R R S R
Sbjct: 172 LVEDKPGSRRRR--------SYSRSRSHSRSRSRSRHS--------------------RK 203
Query: 590 SPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSE 649
S S S S SS ++S SRS S S SRS + SR+PS SRS S
Sbjct: 204 SRSRSGSSKSSH--SKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKE-KSRSRSH 260
Query: 650 SGG 652
S G
Sbjct: 261 SAG 263
>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
Length = 1984
Score = 96.3 bits (238), Expect = 8e-20
Identities = 139/468 (29%), Positives = 166/468 (35%), Gaps = 57/468 (12%)
Query: 183 KKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRR-HRSRSSKCKRKEKNKEKK 241
KK +E S S L V+ R R GS KR HR K KE N
Sbjct: 1487 KKNFYRNETSSQESKNLSTPGTRVQA--RGRILPGSPVKRTWHRHLKDKLTHKEHN---- 1540
Query: 242 RPHTESPGRRSHRH-SSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSP 300
H R+ R S + H+PS +H S S R S + R S S ++
Sbjct: 1541 --HPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNH 1598
Query: 301 SPSGGSGWGSP-QRNGGSGQRSGAHGGRPGSAHSPPDKPS-SPSPRVRDKAAAAAPTPPA 358
S W SP QRN S H HSP + PS R +P
Sbjct: 1599 SSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHH-------SPSE 1651
Query: 359 RGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRG 418
R SPS RS SS R R+ +R R S S +P R R P RG
Sbjct: 1652 RSHRSPSERSHRSSSERRHRSPS-------QRSHRGPSERSHCSPSERRHRSPSQRSHRG 1704
Query: 419 SSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHG 478
S R S S R SER H +R+ P R SPS +H
Sbjct: 1705 PSE---RRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERR--HHSPSERSHC 1759
Query: 479 RRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRS-AEKRPHSPSRSPSPKKPLSRDKDGE 537
P RS S PS+ R RS +E+R HSPS S P R
Sbjct: 1760 --------------SPSERSHCS---PSERRHRSPSERRHHSPSEK-SHHSPSERSHHSP 1801
Query: 538 G-RARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSS 596
R RHS E +R RS+ +RR RRI+ P SP S
Sbjct: 1802 SERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSR 1861
Query: 597 CLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHS 644
C S+ R HS S HS S RSH + S R RT S+ S
Sbjct: 1862 CSPSE--RRGHSSSGKTCHSP---SERSHRSPSGMRQ-GRTSERSHRS 1903
Score = 81.6 bits (200), Expect = 2e-15
Identities = 126/440 (28%), Positives = 154/440 (35%), Gaps = 104/440 (23%)
Query: 205 SVKKHRR--DRSDSGSRRKRRHR-SRSSKCKRKEKNKEK----------KRPHTESPGRR 251
S + HR +RS S +R H S+ S C KN +R H P R
Sbjct: 1562 SWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERS 1621
Query: 252 SHRHSSGSSHSPSLSSHYSDS------------RSPSRLSPKHRDEGR-KTGSQRSSGSR 298
H S HSPS SH S RSPS S + E R ++ SQRS R
Sbjct: 1622 CHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRS--HR 1679
Query: 299 SPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPA 358
PS S +R+ QRS H G H P K S SP A + +P
Sbjct: 1680 GPSERSHCS-PSERRHRSPSQRS--HRGPSERRHHSPSKRSHRSP-----ARRSHRSPSE 1731
Query: 359 RGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRG 418
R SPS RS S RR RS S S R +P
Sbjct: 1732 RSHHSPSERSHHSPS------------ERRHHSPSERSHCSPS-------ERSHCSPSER 1772
Query: 419 SSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERP-PRARPASTSPSPGAH 477
RS S R S S +P SER H +R + P R+R + S
Sbjct: 1773 RHRSPSERRHHSPSEKSHHSP-------SERSHHSPSERRRHSPLERSRHSLLERS---- 1821
Query: 478 GRRGGPEGKSSSRSPGPHPRSWSSSRSPS---------KSRSRSAEKRPHSPSRSP--SP 526
R E +S H R S SPS +SR +E+R HS S SP
Sbjct: 1822 -HRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSP 1880
Query: 527 KKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPY 586
+ R G + R SE RS+ +R R SPS M P R
Sbjct: 1881 SERSHRSPSGMRQGRTSE----------RSHRSSCERTRHSPSEMRPGR----------- 1919
Query: 587 YRPSPSSSSSCLSSDYSTRS 606
PS + C S+ S RS
Sbjct: 1920 ----PSGRNHCSPSERSRRS 1935
Score = 80.5 bits (197), Expect = 5e-15
Identities = 106/401 (26%), Positives = 135/401 (33%), Gaps = 48/401 (11%)
Query: 157 KHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECS-----CGSSSPLRKKKKSVKKHRR 211
+H S S S +K RS + + CS C S S S + HR
Sbjct: 1581 RHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHR- 1639
Query: 212 DRSDSGSRRKRRH----RSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSH-SPSLS 266
G ++R H RS S +R ++ ++R SP +RSHR S SH SPS
Sbjct: 1640 -----GPSQRRHHSPSERSHRSPSERSHRSSSERRHR--SPSQRSHRGPSERSHCSPSER 1692
Query: 267 SHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGG 326
H S S+ R + R S RS RS SP H
Sbjct: 1693 RHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHS 1752
Query: 327 RPGSAHSPPDKPSSPSP---RVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGA 383
+H P + S SP R R + +P + SPS RS S R
Sbjct: 1753 PSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSER-------- 1804
Query: 384 GRRRRRRRRRRRS---RSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPG 440
RR R R S RS S RR R + R S RS S + S S R
Sbjct: 1805 -RRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCS 1863
Query: 441 PGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWS 500
P RGH GK R+ SPS GR +SS P
Sbjct: 1864 PS----ERRGHSSSGKTCHSPSERSH---RSPSGMRQGRTSERSHRSSCERTRHSPSEMR 1916
Query: 501 SSRSPSKSRSRSAEKRPHSPSR--------SPSPKKPLSRD 533
R ++ +E+ SP + P LSRD
Sbjct: 1917 PGRPSGRNHCSPSERSRRSPLKEGLKYSFPGERPSHSLSRD 1957
Score = 68.6 bits (166), Expect = 2e-11
Identities = 91/311 (29%), Positives = 118/311 (37%), Gaps = 40/311 (12%)
Query: 149 RGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKK 208
R HRG + S SP ++ + R +RR S SP R+ +S +
Sbjct: 1676 RSHRGPSER----SHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSE 1731
Query: 209 ---HRRDRSDSGSRRKRRHRSRS--SKCKRKEKN--KEKKRPHTESPGRRSHRHSSGSSH 261
H S +RRH S S S C E++ +R H RR H S S H
Sbjct: 1732 RSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHH 1791
Query: 262 SPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRS 321
SPS SH+S S R SP R R + +RS RSP S +R+ S +RS
Sbjct: 1792 SPSERSHHSPSER-RRHSPLER--SRHSLLERS--HRSP---------SERRSHRSFERS 1837
Query: 322 GAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAG 381
H +HSP +K S SP R + +P R S S ++ S R R+
Sbjct: 1838 --HRRISERSHSPSEK-SHLSPLERSRC-----SPSERRGHSSSGKTCHSPSERSHRSPS 1889
Query: 382 GAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRG---SSRSLSRARSSSDSGSGRGA 438
G R+ R RS S+ R RP P G S S RS G
Sbjct: 1890 G----MRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSF 1945
Query: 439 PGPGPEPGSER 449
PG P R
Sbjct: 1946 PGERPSHSLSR 1956
Score = 65.9 bits (159), Expect = 1e-10
Identities = 140/591 (23%), Positives = 207/591 (35%), Gaps = 90/591 (15%)
Query: 133 DDDDGPVDCDCPASCY--RGHRGY-----RTK-----HWSSSSASPPPKKKKKKKGGHRR 180
D GP P Y RG R +TK H+ + P+ + +R
Sbjct: 1216 DLQSGPSQSPAPVQVYIRRGQRSRPDLVEKTKTRAPGHYEFTQVHNLPESDSESTQNEKR 1275
Query: 181 SRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGS-------------RRKRRHRSR 227
++ + + S+ S P+++ K ++KHR+ ++S + RRKR ++
Sbjct: 1276 AKVRTKKTSD----SKYPMKRITKRLRKHRKFYTNSRTTIESPSRELAAHLRRKRIGATQ 1331
Query: 228 SSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHS--PSLSSHYSDSRSPSRL------S 279
+S K + K+ +P +S + + ++H S+ D P L
Sbjct: 1332 TSTASLKRQPKKPSQPKFMQLLFQSLKRAFQTAHRVIASVGRKPVDGTRPDNLWASKNYY 1391
Query: 280 PKH--RDEGRKTGSQRSSGSRSPSPSGGSG-------WGSPQRNGGSGQRSGAHGGRPGS 330
PK RD + +R S GS WG + + Q A+ +P
Sbjct: 1392 PKQNARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRSAQQPRRAYSFQPRP 1451
Query: 331 AHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSP------RSAPSSQGRGGRAAGGAG 384
P KP+ + + A+ K+S S R+ SSQ + G
Sbjct: 1452 LRLP--KPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTR 1509
Query: 385 RRRRRRR------RRRRSRSSASAPRRRGRRRP---RPAPPRGSSRSLSRARSSSDSGSG 435
+ R R +R R + P R PRG S R R + +
Sbjct: 1510 VQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSE---RTRHNPSWRNH 1566
Query: 436 RGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSP----SPGAHGRRGGPEGKSSSRS 491
R ER H +R+ P R +S S SP PE S S
Sbjct: 1567 RSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLS 1626
Query: 492 P-GPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRA 550
G H S S R PS+ R S +R H RSPS + S + R S ++ +
Sbjct: 1627 ERGLHSPSQRSHRGPSQRRHHSPSERSH---RSPSERSHRSSSE----RRHRSPSQRSHR 1679
Query: 551 RRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRS 610
RS+ +RR SPS R S R+ P R S + S HS S
Sbjct: 1680 GPSERSHCSPSERRHRSPS-QRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPS 1738
Query: 611 PSPGHS-----HGSYSSRSHGTRSRTR--SPS----RTPSPSYHSRSSSES 650
HS H S S RSH + S SPS R+PS H S +S
Sbjct: 1739 ERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKS 1789
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 95.5 bits (236), Expect = 1e-19
Identities = 129/520 (24%), Positives = 183/520 (35%), Gaps = 48/520 (9%)
Query: 156 TKHWSSSSASPPPKKKKKKKG----------GHRRSRKKRRLESECSCGSSSPL-RKKKK 204
++H S S SP P + + + G G+ R R E G SS L ++ +
Sbjct: 531 SRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESR 590
Query: 205 SVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSH--RHSSGSSHS 262
S + + S S H S + + H + G+ S +H SGSS S
Sbjct: 591 SGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQ----HGATSGQSSSHGQHGSGSSQS 646
Query: 263 PSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGS--GQR 320
S Y S S SP G G S G GSGW S GS GQ
Sbjct: 647 ----SRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHG----SGSGWSSSNGPHGSVSGQS 698
Query: 321 SG---AHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQ-GRG 376
SG G S +S SS S R + + + + S S S+ Q G G
Sbjct: 699 SGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSG 758
Query: 377 GRAAGGAGRRRR---RRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSG 433
+ G GR+ R R SS+ G+ GS S S + +SG
Sbjct: 759 SHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQH--------GSGTSCSSSCGHYESG 810
Query: 434 SGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPG 493
SG+ + E GS +G+ HG + + R STS + G+ G+SSS G
Sbjct: 811 SGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSY--G 868
Query: 494 PHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRR 553
H + + + S S + H S S + P S + G G R S + +
Sbjct: 869 QHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSP-SYGRHGSGSGRSSSSGRHGSGSG 927
Query: 554 SRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSP 613
S + S + + S Y + S S S + + S S S
Sbjct: 928 QSSGFGHKSSSGQSSGYTQH---GSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYG 984
Query: 614 GHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESGGF 653
H GS S HG S +PS H S +S +
Sbjct: 985 QHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY 1024
Score = 94.7 bits (234), Expect = 2e-19
Identities = 139/531 (26%), Positives = 190/531 (35%), Gaps = 36/531 (6%)
Query: 150 GHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGS---SSPLRKKKKSV 206
G G + SSS P + G H S + S+ GS S + +S
Sbjct: 2082 GRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSG 2141
Query: 207 KKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLS 266
+ R +R S S R+ S ++ + + SP R RH SGS HS S
Sbjct: 2142 QSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRG--RHGSGSGHSSSHG 2199
Query: 267 SHYSDS-RSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSP------QRNGGSGQ 319
H S S RS SR + R Q SGS S G GS Q SGQ
Sbjct: 2200 QHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQ 2259
Query: 320 RS-----GAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQG 374
S G+ G+ S+H SS S + + + +P +RG+ S SS G
Sbjct: 2260 SSTFDQEGSSTGQ-SSSHGQHGSGSSQSSSYGQQGSGSGQSP-SRGRHG-SGSGHSSSYG 2316
Query: 375 RGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGS 434
+ G +G + R +S + GS S S + S SG
Sbjct: 2317 QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQ 2376
Query: 435 GRGAPGPGPEPGSERGHGGHGKRAKERPPRARPAS---TSPSPGAHGRRGGPEGKSSSRS 491
G GS +G HG +++ + S SPSP + GR G G+SSS S
Sbjct: 2377 SSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP-SRGRHGSGSGQSSSYS 2435
Query: 492 PGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRAR 551
P WSSSR P +S S + H SRS + H + +T +
Sbjct: 2436 PYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQ 2495
Query: 552 RRS---------RSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDY 602
S +S S + S S R+ + + + P R S S S
Sbjct: 2496 SSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHG 2555
Query: 603 STRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESGGF 653
S RS S G HGS S G S ++ S S H S S G+
Sbjct: 2556 S--GSGRSSSSGQ-HGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGY 2603
Score = 88.6 bits (218), Expect = 2e-17
Identities = 140/552 (25%), Positives = 186/552 (33%), Gaps = 76/552 (13%)
Query: 149 RGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGS-----SSPLRKKK 203
RG R +R+ SSSS ++ G R+ R+ S GS SS +
Sbjct: 269 RGER-HRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGS 327
Query: 204 KSVKKHRRDRSDSGSRRKR---RHRSRSSKCKRKEKNKEKKRPHTESPGRR--------- 251
S + R +SGS + +H S S + K+ H+ S G+
Sbjct: 328 GSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSG-HSSSQGQHGSTSGQASS 386
Query: 252 SHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTG-SQRSSGSRSPSPSG--GSGW 308
S +H S S S S H S SR S G+ G QR SGS SG G+G+
Sbjct: 387 SGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGF 446
Query: 309 GSPQRNG----GSGQRSG---------------AHGGRPG--SAHSPPDKPSSPSPRVRD 347
G +G GSG SG HG G S H S S R
Sbjct: 447 GRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGER 506
Query: 348 KAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRG 407
+ ++A + S S +S S+ G + R R R+S S G
Sbjct: 507 QGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSG 566
Query: 408 RRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARP 467
R R GS S S SG G G G HG HG + + +
Sbjct: 567 RSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQH 626
Query: 468 ASTSPSPGAHGRRG---------GPEGKSSSRSP--GPHPRSWSSSRSPSKSRSRSAEKR 516
+TS +HG+ G G +G S +SP G H + S S + S S
Sbjct: 627 GATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSS 686
Query: 517 PHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRI 576
+ P S S + K G G+ S + S S + R S
Sbjct: 687 SNGPHGSVSGQSSGFGHKSGSGQ---SSGYSQHGSGSSHSSGYRKHGSRSGQS------- 736
Query: 577 TSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSR 636
R SSS LSS Y S G HG S S + SR R S
Sbjct: 737 ----------SRSEQHGSSSGLSSSYGQHGSGSHQSSG--HGRQGSGSGHSPSRVRHGSS 784
Query: 637 TPSPSYHSRSSS 648
+ S H + S
Sbjct: 785 SGHSSSHGQHGS 796
Score = 86.7 bits (213), Expect = 6e-17
Identities = 140/550 (25%), Positives = 183/550 (33%), Gaps = 71/550 (12%)
Query: 151 HRGYRTKHWSSSSASPPPKKKKKKKG----------GHRRSRKKRRLESECSCGSSSPLR 200
H R +H S S SP ++ G G RS R S G SS
Sbjct: 876 HASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGS--GSGQSSGFG 933
Query: 201 KKKKSVKKHRRDRSDSGSRRK---RRHRSRSSKCKRKEKNKEKKRPHT----------ES 247
K S + + SGS +H SRS + R E++ + +S
Sbjct: 934 HKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQS 993
Query: 248 PGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEG-------RKTGSQRSSG---- 296
G H SG S SPS H S S S P G ++GS SSG
Sbjct: 994 LGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHR 1053
Query: 297 -SRSPSPSGGSGWGSP--------QRNGGSGQRS--GAHGGRPG--SAHSPPDKPSSPSP 343
SRS SG GS Q SGQ S G HG G S+H SS S
Sbjct: 1054 ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSS 1113
Query: 344 RVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAP 403
+ + + +P G+ R +PS GR G +G + + S
Sbjct: 1114 GYGRQGSGSGQSP-GHGQRGSGSRQSPS-YGRHGSGSGRSSSSGQHGSGLGESSGFGHHE 1171
Query: 404 RRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPP 463
G+ GS S + S SG G GS +G HG +++
Sbjct: 1172 SSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSG 1231
Query: 464 RARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRS 523
R S S + GR G G SSS SSSR P +SRS HS
Sbjct: 1232 HGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRS------GHS---- 1281
Query: 524 PSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRP 583
+ + G G HS A + S + S + +S +
Sbjct: 1282 ----SVFGQHESGSG---HSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSS 1334
Query: 584 IPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYH 643
+R S SS SS + +SPS G HGS S S + S H
Sbjct: 1335 SYGHRGSGSSQSSGYGRHGA--GSGQSPSRGR-HGSGSGHSSSYGQHGSGSGWSSSSGRH 1391
Query: 644 SRSSSESGGF 653
S +S GF
Sbjct: 1392 GSGSGQSSGF 1401
Score = 86.3 bits (212), Expect = 8e-17
Identities = 138/569 (24%), Positives = 191/569 (33%), Gaps = 85/569 (14%)
Query: 157 KHWSSSSASPPPKKKKKKKGGHRRSR----------KKRRLESECSCGSSSPL-RKKKKS 205
+H S S SP P + + G + S R E G SS L ++ +S
Sbjct: 1938 QHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRS 1997
Query: 206 VKKHRRDRSDSGSRRKRRH------RSRSSKCKRKEKNKEKKRPHTESPGRRSH-----R 254
+ + S S H +SS C + + + H + S R
Sbjct: 1998 GQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGR 2057
Query: 255 HSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGS---- 310
SGS SP + S SR SP + G +G SSG P SG+G
Sbjct: 2058 QGSGSGQSPG----HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESS 2113
Query: 311 -------PQRNGGSGQRS--GAHGGRPG-SAHSPPDKPSSPSPRVRDKAAAAAPTPPARG 360
Q GSG S G HG R G S+ SS S + + + G
Sbjct: 2114 SGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHG 2173
Query: 361 KESPSPRSAPSSQGRGGRAAG--------GAGRRRRRRRRRRRSRSSASA-----PRRRG 407
++ +P S+GR G +G G+G R R SRS S+ G
Sbjct: 2174 RQGSGSGHSP-SRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSG 2232
Query: 408 RRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARP 467
GS S+ + S SG G G HG HG + + +
Sbjct: 2233 HSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQ 2292
Query: 468 ASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPK 527
S S + GR G G SSS WSSS S S + H S S
Sbjct: 2293 GSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHES-SSWQS 2351
Query: 528 KPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPY- 586
++ G G + E +R+ + SR + S S + S ++ + +
Sbjct: 2352 SGYTQHGSGSGHSSSYEQHGSRSGQSSRG----ERHGSSSGSSSSYGQHGSGSRQSLGHG 2407
Query: 587 -------YRPSPS----SSSSCLSSDYSTR------SHSRSP---SPGHSHG-----SYS 621
PSPS S S SS YS S SR P GHS G S S
Sbjct: 2408 QHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRS 2467
Query: 622 SRSHGTRSRTRSPSRTPSPSYHSRSSSES 650
+S G S + + H +S +S
Sbjct: 2468 GQSSGYGQHGSSSGHSSTHGQHGSTSGQS 2496
Score = 84.0 bits (206), Expect = 4e-16
Identities = 149/575 (25%), Positives = 192/575 (33%), Gaps = 87/575 (15%)
Query: 150 GHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKH 209
GH +H S S S + ++ G S + S SS R+ S
Sbjct: 2128 GHSSGYGQHGSRSGQS----SRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSP 2183
Query: 210 RRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRS--HRHSSGSSHSPSLSS 267
R R SGS H S R + P+ G S +H SGS HS + S
Sbjct: 2184 SRGRHGSGSGHSSSHGQHGSGSGRSSS----RGPYESRSGHSSVFGQHESGSGHSSAYSQ 2239
Query: 268 HYSDSR---------SPSRLSPKHRDEGRKTGS-----QRSSGSRSPSPSGGSGWGSPQ- 312
H S S S S S EG TG Q SGS S G G GS Q
Sbjct: 2240 HGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQS 2299
Query: 313 ----RNG-GSGQRS--GAHG---------GRPGSAHSPPD---KPSSPSPRVRDKAAAAA 353
R+G GSG S G HG GR GS S S + +
Sbjct: 2300 PSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGS 2359
Query: 354 PTPPARGKESPSPRSAPSSQG-RGGRAAG--------GAGRRRRRRRRRRRSRSSASAPR 404
+ + E RS SS+G R G ++G G+G R+ + S S S
Sbjct: 2360 GSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP 2419
Query: 405 RRGRR-----RPRPAPPRGSSRSLSRARSSSDSGSGR---------------GAPGPGPE 444
RGR + P GS S +R +SGSG G G
Sbjct: 2420 SRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSS 2479
Query: 445 PGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRG---------GPEGKSSSRSPGPH 495
G HG HG + + + ++S +HG+ G G +G S +SPG
Sbjct: 2480 SGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHG 2539
Query: 496 PRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSR 555
R S +SPS R S R S + S S E + S + +
Sbjct: 2540 QRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGH 2599
Query: 556 SYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPG- 614
S + R S R +S+ +Y S S +SPS G
Sbjct: 2600 SSGYGQHGSRSGQSSRGERHGSSSGSS--SHYGQHGSGSRQSSGHGRQGSGSGQSPSRGR 2657
Query: 615 HSHGSYSSRSHGTR--SRTRSPSRTPSPSYHSRSS 647
H G S SHG RS SR P S SS
Sbjct: 2658 HGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSS 2692
Score = 81.6 bits (200), Expect = 2e-15
Identities = 124/546 (22%), Positives = 163/546 (29%), Gaps = 82/546 (15%)
Query: 122 GAEPGLEYAPFDDDDG------PVDCDCPASCYRGHRGYRTKHWSSSSASPPPKKKKKKK 175
G+ Y+P+ G P + S GHR R+ S
Sbjct: 1487 GSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTH 1546
Query: 176 GGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKE 235
G H + + SCG + S +H S S ++ S S +
Sbjct: 1547 GQHGSTSGQ-----SSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQR 1601
Query: 236 KNKEKKRP----HTESPGRRSH--RHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKT 289
+ ++ P H GR S +H SG S H S S S S G +
Sbjct: 1602 GSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSS 1661
Query: 290 GSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGG--RPGSAHSPPDKPSSPSPRVRD 347
G + GSRS S G GS R S R G HG R S H S SP
Sbjct: 1662 GYGQH-GSRSGQSSRGERHGSSSR---SSSRYGQHGSGSRQSSGHGRQGSGSGQSP---- 1713
Query: 348 KAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRG 407
+RG+ S SS G+ G +G + R R S G
Sbjct: 1714 ----------SRGRHG-SGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSG 1762
Query: 408 RRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARP 467
GS S+ + S SG G G HG HG + + +
Sbjct: 1763 HSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQ 1822
Query: 468 ASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPK 527
S S + GR G G SSS WSSS S S + H S S
Sbjct: 1823 GSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQ-S 1881
Query: 528 KPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYY 587
++ G G + E +R+ + SR
Sbjct: 1882 SGYTQHGSGSGHSSSYEQHGSRSGQSSRG------------------------------- 1910
Query: 588 RPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSS 647
SSS SS Y H GS S HG S +PS H S
Sbjct: 1911 --EQHGSSSGSSSSYGQ----------HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS 1958
Query: 648 SESGGF 653
+S +
Sbjct: 1959 GQSSSY 1964
Score = 80.1 bits (196), Expect = 6e-15
Identities = 127/503 (25%), Positives = 170/503 (33%), Gaps = 62/503 (12%)
Query: 195 SSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKK-----RPHTESPG 249
S S LR ++ + + ++R+ S SS + + + +P TES
Sbjct: 97 SGSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESIS 156
Query: 250 RR-------SHRHSSGSSHSPSLSSHYSDSR---------SPSRLSPKHRDEGRKTGSQR 293
RR S +H+S S S S SDS S S SP + G +GS +
Sbjct: 157 RRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQHG--SGSGQ 214
Query: 294 SSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAA 353
SS + + G G Q SGQ SG GS HS S + + +
Sbjct: 215 SSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHS--------SGYGQHGSRSGQ 266
Query: 354 PTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRP 413
+ R + S S+ G G R + G GR+ R+ S S G
Sbjct: 267 SSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQ---SPSHVRHGSGSGHSSSHG 323
Query: 414 APPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPS 473
GSS S SR S SG G G G+ HG + + + STS
Sbjct: 324 QHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQ 383
Query: 474 PGAHGRRGGPEGKSSS----------------------RSPGPHPRSWSSSRSPSKSRSR 511
+ G+ G +SSS +SPG R S +SPS +
Sbjct: 384 ASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHG 443
Query: 512 SAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFM 571
+ R S S S E + HS S + R S
Sbjct: 444 TGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSR 503
Query: 572 EPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPG-HSHGSYSSRSHGTR-- 628
R+ +SA S S S S S S SPS G H GS S S+G
Sbjct: 504 GERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGY 563
Query: 629 SRTRSPSRTPSPSYHSRSSSESG 651
RS SR P Y S S SG
Sbjct: 564 GSGRSSSRGP---YESGSGHSSG 583
Score = 80.1 bits (196), Expect = 6e-15
Identities = 136/536 (25%), Positives = 172/536 (32%), Gaps = 67/536 (12%)
Query: 150 GHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKH 209
GH +H S S S + ++ G S S SS R+ S
Sbjct: 1188 GHSSGYGQHGSRSGQS----SRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSP 1243
Query: 210 RRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRS--HRHSSGSSHSPSLSS 267
R R SG H S R + P+ G S +H SGS HS + S
Sbjct: 1244 SRGRHGSGLGHSSSHGQHGSGSGRSSS----RGPYESRSGHSSVFGQHESGSGHSSAYSQ 1299
Query: 268 HYSDSR---------SPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSG 318
H S S S S S EG TG S G R S SG+G G
Sbjct: 1300 HGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQS 1359
Query: 319 QRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGR 378
G HG G + S S ++++ G+ S SS G
Sbjct: 1360 PSRGRHGSGSGHSSSYGQHGSGSG-----WSSSSGRHGSGSGQSSGFGHHESSSWQSSGC 1414
Query: 379 AAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGA 438
G+G + SRS S+ RG R SSS S S G
Sbjct: 1415 TQHGSGSGHSSSYEQHGSRSGQSS---RGERHG----------------SSSGSSSSYGQ 1455
Query: 439 PGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRS 498
G G G G G P R R S S ++ G G SSSR P S
Sbjct: 1456 HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSS 1515
Query: 499 WSSSRSPSKSRS-RSAEKRPHSPSRSPSPKKPLSRDKDGEG-----RARHSEAEATRARR 552
SS +SRS +S+ H S S G+ S ++ +
Sbjct: 1516 HSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQH 1575
Query: 553 RSRSYSPIRKRRRDSPSFMEP---RRITSARKRPIPYYRPSPSSSSSCLSSDYST----- 604
S S R+ S S P +R + +R+ P Y R S S S + +
Sbjct: 1576 GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSP-SYGRHGSGSGRSSSSGQHGSGLGES 1634
Query: 605 ------RSHSRSPSPGHSHGSYSSRSHG---TRSRTRSPSRTPSPSYHSRSSSESG 651
S S S HGS S S G SR+ SR SRSSS G
Sbjct: 1635 SGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYG 1690
Score = 79.7 bits (195), Expect = 8e-15
Identities = 123/516 (23%), Positives = 155/516 (30%), Gaps = 78/516 (15%)
Query: 150 GHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKH 209
GH +H S S S + ++ G RS + S SS R+ S +
Sbjct: 1658 GHSSGYGQHGSRSGQS----SRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSP 1713
Query: 210 RRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRS--HRHSSGSSHSPSLSS 267
R R SG H S R + P+ G S +H SGS HS + S
Sbjct: 1714 SRGRHGSGLGHSSSHGQHGSGSGRSSS----RGPYESRSGHSSVFGQHESGSGHSSAYSQ 1769
Query: 268 HYSDSR---------SPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSG 318
H S S S S S EG TG S G S S +G G
Sbjct: 1770 HGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQS 1829
Query: 319 QRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGR 378
G HG G + S S ++++ G+ S SS G
Sbjct: 1830 PSRGRHGSGSGHSSSYGQHGSGSG-----WSSSSGRHGSGSGQSSGFGHHESSSWQSSGY 1884
Query: 379 AAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGA 438
G+G + SRS S+ RG SSS S S G
Sbjct: 1885 TQHGSGSGHSSSYEQHGSRSGQSS--------------RGEQHG-----SSSGSSSSYGQ 1925
Query: 439 PGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRS 498
G G G G G P R R S S ++G G G SSSR GP+
Sbjct: 1926 HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSR--GPYESG 1983
Query: 499 WSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYS 558
S SRS + + S S HS +S S
Sbjct: 1984 SGHSSGLGHRESRSGQSSGYGQHGSSS---------------GHSSTHGQHGSASGQSSS 2028
Query: 559 PIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHG 618
+ S + S S SS Y + SPGH
Sbjct: 2029 CGQHGASSGQSSSHGQH-----------------GSGSSQSSGYGRQGSGSGQSPGHGQR 2071
Query: 619 SYSSRSHGTRSRTRSPS-RTPSPSYHSRSSSESGGF 653
SR + R S S R+ S H ES GF
Sbjct: 2072 GSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGF 2107
Score = 79.0 bits (193), Expect = 1e-14
Identities = 135/536 (25%), Positives = 188/536 (35%), Gaps = 54/536 (10%)
Query: 150 GHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKH 209
GH + +H S+S S + G S + S + G +S
Sbjct: 836 GHFSSQGRHGSTSGQSSS-SGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHG 894
Query: 210 RRDRSDSGSRRKRRH-----RSRSSKCKRKEKNKEKKRPHTESPGRRSH--RHSSGSSHS 262
+R S RH RS SS + H S G+ S +H SGS HS
Sbjct: 895 QRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHS 954
Query: 263 PSLSSHYSDSRSPSRLSPKHRDEGRKTGS--QRSSGSRSPSPSGGSGWGSPQRNGGSGQR 320
S H S S SR S +H + S Q SGSR G G GS Q S R
Sbjct: 955 SSYEQHGSRSGQSSR-SEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGR 1013
Query: 321 SGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAA 380
G+ G+ S++ P S S + + + +ES S +S S G+ G ++
Sbjct: 1014 HGSGSGQ-SSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQS--SGYGQHGSSS 1070
Query: 381 GGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPG 440
G + + +S S G+ SS + SS SG GR G
Sbjct: 1071 GHSSTHGQHGSTSGQSSSCGQHGASSGQ---------SSSHGQHGSGSSQSSGYGRQGSG 1121
Query: 441 PGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWS 500
G PG HG G +++ P R S S + G+ G G+SS G H S
Sbjct: 1122 SGQSPG----HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGF--GHHESSSG 1175
Query: 501 SSRSPSKSRSRSAEKRPHSPSRSPSPKKPL-SRDKDGEGRARHSEAEATRARRRS----- 554
S S S+ S S + S S + R G + H + +R+ S
Sbjct: 1176 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQ 1235
Query: 555 ---RSYSPIRKRRRD----SPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSH 607
+SP R R S S + + PY S S SS S H
Sbjct: 1236 GSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPY--ESRSGHSSVFGQHESGSGH 1293
Query: 608 SRSPS-----PGH-----SHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESGGF 653
S + S GH HGS S +S S ++ S + SS+S G+
Sbjct: 1294 SSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGY 1349
Score = 78.2 bits (191), Expect = 2e-14
Identities = 125/542 (23%), Positives = 165/542 (30%), Gaps = 67/542 (12%)
Query: 157 KHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRK--KKKSVKKHRRDRS 214
+H S S SP P + + G + S S P S HR RS
Sbjct: 1468 QHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRS 1527
Query: 215 DSGSRRKRR-----HRSRSSKCKRKEKNKEKKRPHTESPGRRSH--RHSSGSSHSPSLSS 267
S + H S + H S G+ S +H SGSS S
Sbjct: 1528 GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGR 1587
Query: 268 HYSDS-RSP--------SRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSG 318
S S +SP SR SP + G +G SSG SG+G + + G
Sbjct: 1588 QGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQS 1647
Query: 319 QRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGR 378
HG G + S R + ++ +R + S S GR G
Sbjct: 1648 SSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGS 1707
Query: 379 AAG---------------------GAGRRRRRRRRRRRSRSSASA-----PRRRGRRRPR 412
+G G+G R R SRS S+ G
Sbjct: 1708 GSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAY 1767
Query: 413 PAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSP 472
GS S+ + S SG G G HG HG + + + S S
Sbjct: 1768 SQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSG 1827
Query: 473 SPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSR 532
+ GR G G SSS WSSS S S + H S S ++
Sbjct: 1828 QSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHES-SSWQSSGYTQ 1886
Query: 533 DKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPS 592
G G + E +R+ + SR E +S Y S
Sbjct: 1887 HGSGSGHSSSYEQHGSRSGQSSRG---------------EQHGSSSGSSSS---YGQHGS 1928
Query: 593 SSSSCLSSDYSTRSHSRSPSPG---HSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSE 649
S L +SPSP H GS S S+G S + P Y S S
Sbjct: 1929 GSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGP-YESGSGHS 1987
Query: 650 SG 651
SG
Sbjct: 1988 SG 1989
Score = 66.6 bits (161), Expect = 7e-11
Identities = 95/403 (23%), Positives = 128/403 (31%), Gaps = 32/403 (7%)
Query: 122 GAEPGLEYAPFDDDDGPVDCDCPASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRS 181
G+ Y+P+ G P GH H S S + GH +
Sbjct: 2427 GSGQSSSYSPYGSGSGWSSSRGPYESGSGHSS-GLGHRESRSGQSSGYGQHGSSSGHSST 2485
Query: 182 RKKRRLES--ECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKE 239
+ S SCG + S +H S S ++ S S + +
Sbjct: 2486 HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2545
Query: 240 KKRP----HTESPGRRSH--RHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQR 293
++ P H GR S +H SG S H S S S S G +G +
Sbjct: 2546 RQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 2605
Query: 294 SSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGG--RPGSAHSPPDKPSSPSPRVRDKAAA 351
GSRS S G GS + GS G HG R S H S SP
Sbjct: 2606 H-GSRSGQSSRGERHGS---SSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSP-------- 2653
Query: 352 AAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRP 411
+RG+ S SS G+ G +G + R R S G
Sbjct: 2654 ------SRGRHG-SGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSA 2706
Query: 412 RPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTS 471
GS S+ + S SG G G +G G + + R + S
Sbjct: 2707 YSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGS 2766
Query: 472 PSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAE 514
+HGR G G+SSS G H S S+ S S +
Sbjct: 2767 GQSLSHGRHGSGSGQSSSY--GQHGSGSGQSSGYSQHGSGSGQ 2807
Score = 54.3 bits (129), Expect = 3e-07
Identities = 95/377 (25%), Positives = 125/377 (33%), Gaps = 41/377 (10%)
Query: 150 GHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPL---RKKKKSV 206
GH +H S+S S G H S + + GSS R+ S
Sbjct: 2481 GHSSTHGQHGSTSGQS-------SSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSG 2533
Query: 207 KKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSL- 265
+ + SGSR+ + S R + + ES G H SSG S S S
Sbjct: 2534 QSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQH 2593
Query: 266 ------SSHYSDSRSPSRLSPKHRDEGRKTGS-----QRSSGSRSPSPSGGSGWGSPQRN 314
SS Y S S S + G +GS Q SGSR S G G GS
Sbjct: 2594 GSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGS---- 2649
Query: 315 GGSGQRSGAHGGRPG--SAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSS 372
G G HG G S+H S S + + ES S S+ S
Sbjct: 2650 -GQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYS 2708
Query: 373 QGRGGR----AAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARS 428
Q G + G G + + SS G R GSS+S R
Sbjct: 2709 QHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGS------GSSQSSGYGRH 2762
Query: 429 SSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSS 488
+ SG G G +G HG + + ++ S S G +GG
Sbjct: 2763 GAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGG--SNHD 2820
Query: 489 SRSPGPHPRSWSSSRSP 505
S G + S+ SS SP
Sbjct: 2821 GGSSGSYFLSFPSSTSP 2837
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 92.0 bits (227), Expect = 1e-18
Identities = 110/433 (25%), Positives = 163/433 (37%), Gaps = 53/433 (12%)
Query: 162 SSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHR-RDR-----SD 215
++A+ PP +KK ++ R K S + P KKHR RDR +
Sbjct: 508 AAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQPAPPAPASPWDSKKHRSRDRKPGSHAS 567
Query: 216 SGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSP 275
S +RR+ R RSRS +R+ ++ +++R + R R S SP ++ S S
Sbjct: 568 SSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPPPATSSSSSSRR 627
Query: 276 SRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGS------PQRNGGSGQR-SGAHGGRP 328
R KHRD G ++ S SR SG + P + G R S G P
Sbjct: 628 ERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDRDSRRRGAVP 687
Query: 329 GSAHSPPDKPSSPSPRV-----RDKAAAAAPTP-PARGKESPSPRSAPSSQGRGGRAAGG 382
S D R DK+ P+P PA SP S+G G G
Sbjct: 688 PSIQDLTDHDLFAIKRTITVGRLDKSDPRGPSPAPA---SSPKREVLYDSEGLSGEERG- 743
Query: 383 AGRRRRRRRRRRRSRSSASAPRRRGRRRPR---------PAPPRGSSRSLSRARSSSDSG 433
G+ ++ RRR + SS+S+ R +G RR R RS +AR +S
Sbjct: 744 -GKSSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKESA 802
Query: 434 SGRGAPGPGPEPGSERGHGGHGKRAKERPPRARP----------ASTSPSPGAHGRRGGP 483
G P P P S G R + + +ST+P+ A G
Sbjct: 803 PSSGPP-PKPPVSSGSGSSSSSSSCSSRKVKLQSKVAVLIREGVSSTTPAKDAASAGLGS 861
Query: 484 EGKSSSRSPGPHPRSWSSSRSP-SKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARH 542
G SR SRSP K R+ + + S PKK + K G + +
Sbjct: 862 IGVKFSRD--------RESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKAKAGAKKTKG 913
Query: 543 SEAEATRARRRSR 555
++ + ++ R +
Sbjct: 914 TKGKTKPSKTRKK 926
Score = 89.4 bits (220), Expect = 1e-17
Identities = 123/448 (27%), Positives = 175/448 (39%), Gaps = 53/448 (11%)
Query: 244 HTESPGRRSHRHSSGSSHSPSLSSHYSDSR-SPSRLSPKHRDEGRKTGSQRS-SGSRSPS 301
H ES G + + G P+ + +DSR L K + R+ QRS S + +P+
Sbjct: 450 HAESDGEGALQVDLGE---PAPAPPAADSRWGGLDLRRKILTQRRERYRQRSPSPAPAPA 506
Query: 302 PSGGSGWGSPQRNGGSGQRSG-AHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARG 360
P+ +G + +++ +RSG A S+ + P P+ SP K + P +
Sbjct: 507 PAAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQPAPPAPASPWDSKKHRSRDRKPGSHA 566
Query: 361 KESPSPRSAPSSQGRG--------GRAAGGAGRRRRRRRRRRRSRS-------SASAPRR 405
S RS S+ R R GG+ R R R +RRRR RS S+S+ R
Sbjct: 567 SSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPPPATSSSSSSR 626
Query: 406 RGRRRPRPAPPRGSSRSLSRARSSSDSGSGRG---APGPGPEPGSERGHGGHGKRAKERP 462
R R R + GS + R+RS + SG G AP P P P G R +
Sbjct: 627 RERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDRDSRRRGAV 686
Query: 463 PRARPASTSPSPGAHGR--RGGPEGKSSSRSPGPHPRSW--------SSSRSPSKSRSRS 512
P + T A R G KS R P P P S S S + +S
Sbjct: 687 PPSIQDLTDHDLFAIKRTITVGRLDKSDPRGPSPAPASSPKREVLYDSEGLSGEERGGKS 746
Query: 513 AEK---RPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPS 569
++K R + S S S ++ SR K +G R + + R R R RS R + +PS
Sbjct: 747 SQKDRRRSGAASSSSSSREKGSRRKALDGGDR--DRDRDRDRDRDRSSKKARPPKESAPS 804
Query: 570 FMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSH--------SRSPSPGHSHGSYS 621
P K P+ S SSSSSC S +S S +P S
Sbjct: 805 SGPP------PKPPVSSGSGSSSSSSSCSSRKVKLQSKVAVLIREGVSSTTPAKDAASAG 858
Query: 622 SRSHGTRSRTRSPSRTPSPSYHSRSSSE 649
S G + SR+P R+ +E
Sbjct: 859 LGSIGVKFSRDRESRSPFLKPDERAPTE 886
Score = 64.7 bits (156), Expect = 3e-10
Identities = 92/420 (21%), Positives = 144/420 (34%), Gaps = 57/420 (13%)
Query: 160 SSSSASPPPKKKKKKKGGHRRSRKK-RRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGS 218
+SSSA + + + + RRSR RR S R++++S S S S
Sbjct: 566 ASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPPPATSSSSSS 625
Query: 219 RRKR-RHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSR 277
RR+R R + R +K+K + + R S + S S S DSR
Sbjct: 626 RRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDRDSRRRGA 685
Query: 278 LSPKHRD----------EGRKTGSQRSSGSRSPSPSGGS-----------GWGSPQRNGG 316
+ P +D G S R PSP+ S G +R G
Sbjct: 686 VPPSIQDLTDHDLFAIKRTITVGRLDKSDPRGPSPAPASSPKREVLYDSEGLSGEERGGK 745
Query: 317 SGQRSGAHGGRPGSAHSPPDKPS-------------SPSPRVRDKAAAAAPTPPARGKES 363
S Q+ G S+ S +K S R RD+++ A P S
Sbjct: 746 SSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKESAPSS 805
Query: 364 PSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSR-- 421
P P S G G ++ + R+ + +S + R G PA S+
Sbjct: 806 GPPPKPPVSSGSGSSSSSSS-----CSSRKVKLQSKVAVLIREGVSSTTPAKDAASAGLG 860
Query: 422 ----SLSRARSS----------SDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARP 467
SR R S + + + APG ++ K+ K + +P
Sbjct: 861 SIGVKFSRDRESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKAKAGAKKTKGTKGKTKP 920
Query: 468 ASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPK 527
+ T + G GG G+ S + S ++ ++ S S E+R +P PK
Sbjct: 921 SKTRKKVRSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAEETSWSGEERAAKVPSTPPPK 980
Score = 64.3 bits (155), Expect = 3e-10
Identities = 93/353 (26%), Positives = 130/353 (36%), Gaps = 49/353 (13%)
Query: 329 GSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRR 388
G P ++P R AA PTP A S +P + P Q RA G
Sbjct: 394 GEIVQPEEEPRLALSLFRPGGRAARPTPAA----SATPTAQPLPQPPAPRAPEGDDFLSL 449
Query: 389 RRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSR---------SLSRARSSSDSGSGRGAP 439
+ S + P PAPP SR L++ R S AP
Sbjct: 450 H------AESDGEGALQVDLGEPAPAPPAADSRWGGLDLRRKILTQRRERYRQRSPSPAP 503
Query: 440 GPGPEPGSERGHGGHGKRAKERPPRARPASTSPS------PGAHGRRGGPEGKSSSRSPG 493
P P + +R ++R A+ A++S S P + +S R PG
Sbjct: 504 APAPAAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQPAPPAPASPWDSKKHRSRDRKPG 563
Query: 494 PHPRSWSSSRSPSKSRSRSAEKRPHSPSRSP-----SPKKPLSRDKDGEGRARHSEAEAT 548
H +SS + +SRSRS + SRS ++ SR+K R S AT
Sbjct: 564 SH----ASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPPPAT 619
Query: 549 ---------RARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLS 599
R R + R +K+++ S S E R + K P P P PS S+SC
Sbjct: 620 SSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAP--APPPSGSTSCGD 677
Query: 600 SDYSTRSHSRSPSPGH--SHGSYSSRSHGTRSR-TRSPSRTPSPSYHSRSSSE 649
D S R + PS H ++ + T R +S R PSP+ S E
Sbjct: 678 RD-SRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDKSDPRGPSPAPASSPKRE 729
Score = 63.9 bits (154), Expect = 4e-10
Identities = 85/298 (28%), Positives = 108/298 (36%), Gaps = 36/298 (12%)
Query: 366 PRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSR 425
PR A S GGRAA R +SA+ + + P P P G
Sbjct: 403 PRLALSLFRPGGRAA------------RPTPAASATPTAQPLPQPPAPRAPEGDDFLSLH 450
Query: 426 ARSSSDSGS--GRGAPGPGPEPGSERGHGGHGKRAK---ERPPRARPASTSPSPG-AHGR 479
A S + G P P P P ++ GG R K +R R R S SP+P A
Sbjct: 451 AESDGEGALQVDLGEPAPAP-PAADSRWGGLDLRRKILTQRRERYRQRSPSPAPAPAPAA 509
Query: 480 RGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGR 539
GP + SR R S + S S + P +P+ KK SRD+
Sbjct: 510 AAGPPTRKKSR----RERKRSGEAKEAASSSSGTQPAPPAPASPWDSKKHRSRDRKPGSH 565
Query: 540 ARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYR------PSPSS 593
A S ARRRSRS S R RR S S + RR S R R R P +
Sbjct: 566 ASSS------ARRRSRSRSRSRSTRRRSRS-TDRRRGGSRRSRSREKRRRRRRSASPPPA 618
Query: 594 SSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESG 651
+SS SS G SRS G + + P+P+ S+ G
Sbjct: 619 TSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCG 676
Score = 39.7 bits (91), Expect = 0.009
Identities = 61/233 (26%), Positives = 84/233 (36%), Gaps = 22/233 (9%)
Query: 432 SGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRS 491
+ G P P PG G + +E P R A + PG R P ++ +
Sbjct: 373 TAGGAALPPPLLPPGDSEIEEGEIVQPEEEP---RLALSLFRPGGRAARPTPAASATPTA 429
Query: 492 PG----PHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEA 547
P PR+ S E P+P P + + G R
Sbjct: 430 QPLPQPPAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAPPAADSRWGGLDLRRKILTQ 489
Query: 548 TRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSS-------CLSS 600
R R R RS SP + + P R S R+R +SSSS +S
Sbjct: 490 RRERYRQRSPSPA-PAPAPAAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQPAPPAPAS 548
Query: 601 DYSTRSH-SRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESGG 652
+ ++ H SR PG SH S S+R R+RS SR+ S SRS+ G
Sbjct: 549 PWDSKKHRSRDRKPG-SHASSSARR-----RSRSRSRSRSTRRRSRSTDRRRG 595
Score = 39.7 bits (91), Expect = 0.009
Identities = 80/384 (20%), Positives = 121/384 (31%), Gaps = 63/384 (16%)
Query: 92 RQMLMEKEGVLTREDRPGGHIVAETPRLTEGA--------EPGLEYAPFDDDDGPVDCDC 143
R++L + EG L+ E+R G ++ R GA E G D D D D
Sbjct: 728 REVLYDSEG-LSGEERGGKS--SQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDR 784
Query: 144 PASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRR-----SRKKRRLESECSCGSSSP 198
R + R S+ S+ PPPK G S +K +L+S+ +
Sbjct: 785 DRDRDRSSKKARPPKESAPSSGPPPKPPVSSGSGSSSSSSSCSSRKVKLQSKVAVLIREG 844
Query: 199 LRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEK---NKEKKRPHTESPGRRSHRH 255
+ + G + R SRS K E+ K P + P + +
Sbjct: 845 VSSTTPAKDAASAGLGSIGVKFSRDRESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKA 904
Query: 256 SSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRS---SGSRSPSPSGGSGWGSPQ 312
+G+ + PS+ K R G GS S++ S S +G +
Sbjct: 905 KAGAKKTKGTKG----KTKPSKTRKKVRSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAE 960
Query: 313 RNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKES--------- 363
SG+ A PS+P P+ AAP PPA +S
Sbjct: 961 ETSWSGEERAA------------KVPSTPPPK-------AAPPPPALTPDSQTVDSSCKT 1001
Query: 364 PSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSL 423
P P GGA +PA +S +
Sbjct: 1002 PEVSFLPEEATEEAGVRGGAEEEEEEEEEEEEEEE---------EEEQQPATTTATSTAA 1052
Query: 424 SRARSSSDSGSGRGAPGPGPEPGS 447
+ ++ +GS G G P S
Sbjct: 1053 AAPSTAPSAGSTAGDSGAEDGPAS 1076
Score = 35.0 bits (79), Expect = 0.22
Identities = 36/155 (23%), Positives = 55/155 (35%), Gaps = 9/155 (5%)
Query: 403 PRRRGRRRPRPAPPRGSSRSLSRARSSS-DSGSGRGAPGPGPEPGSERGHGGHGKRAKER 461
PR R R + P+ +S + AR + +G G AP P P S +
Sbjct: 149 PRLRAWRTGKTVSPQSNSSRPTCARHLTLGTGDGGPAPPPAPSSASSSPSPSPSSSSPSP 208
Query: 462 PPRARPASTSPSPGAHGRRGGP-EGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSP 520
PP P + P P + SP P P P+ S P S
Sbjct: 209 PPPPPPPAPPAPPAPRFDIYDPFHPTDEAYSPPPAPEQKYDPFEPTGS-------NPSSS 261
Query: 521 SRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSR 555
+ +PSP++ +++ E E E ++ SR
Sbjct: 262 AGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISR 296
Score = 31.6 bits (70), Expect = 2.4
Identities = 14/34 (41%), Positives = 15/34 (44%), Gaps = 2/34 (5%)
Query: 324 HGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPP 357
HG +PG PP P P P DK P PP
Sbjct: 1280 HGRKPGDPPGPPRPPKEPGP--PDKGGPGLPLPP 1311
>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
Length = 819
Score = 91.7 bits (226), Expect = 2e-18
Identities = 117/570 (20%), Positives = 214/570 (37%), Gaps = 97/570 (17%)
Query: 153 GYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKK----KSVKK 208
G R KH P K ++GG ++ +K+RR + + G S + K + K +++
Sbjct: 220 GRRKKH---RRPKPAAGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRR 276
Query: 209 HRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESP-----GRRSHRHSSGSSHSP 263
++ + +G++R+ + + + K ++P G++ R ++ +
Sbjct: 277 QGQNAALAGAKRRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATKAA 336
Query: 264 SLSSHYSDSRSPS------RLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQ-RNGG 316
+ + + K R G+K Q++S + + S GG G + + G
Sbjct: 337 AAGTKRGGGGQQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRG 396
Query: 317 SGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRG 376
G++ KP +PR R + A AA P G + P R +++ RG
Sbjct: 397 DGRK----------------KPRWQNPRRRAQKAPAAK-PRGGGSKKPRRRGPKAAKSRG 439
Query: 377 GRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGR 436
G++ G G++ RRR ++ R +++ + RG ++ + S SG
Sbjct: 440 GKSRSGGGKKPRRRGQKARQKAAEAGAESRGDKKQGRQKASAAGTKSRGGGLKSHSGKNL 499
Query: 437 GAPGPGPEPGSERGHGGHGK-RAKERPPRARPASTSPSPGAHGRR--------------- 480
G E E+ K R +++P R +PA G +
Sbjct: 500 WRRGQKAEAAGEKATAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSH 559
Query: 481 GGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRA 540
GG K S G PR W + + +K+R +K+P + K SR DG +A
Sbjct: 560 GGGGNKQSRGGGGNKPRQWGQTAAAAKTRG-GGDKQPGWQKAAAGVTK--SRSGDGGKKA 616
Query: 541 RHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRP---------SP 591
+A T A+ R + P R+ ++D+ + E T A R +P S
Sbjct: 617 WRQKAAGTGAKSRKK---PWRRGQKDAAA-AEKAWATGATSRGSGGKQPRWQKPAAAGSE 672
Query: 592 SSSSSCLSSDYSTRSHSR--------------------------SPSPGHSHGSYSSRSH 625
SS+++ + + R R P G S G ++S
Sbjct: 673 SSAAAAVGQEAEARKKPRRRRAKSRGDGGQNAAVGINPWQRRGKKPRLGKSRGGGGAKSR 732
Query: 626 GT---RSRTRSPSRTPSPSYHSRSSSESGG 652
G+ +SR +++ S + S S GG
Sbjct: 733 GSGGAKSRGSGGAKSRSGKKAAASKSHGGG 762
Score = 65.5 bits (158), Expect = 2e-10
Identities = 91/404 (22%), Positives = 146/404 (36%), Gaps = 68/404 (16%)
Query: 172 KKKKGG----HRRSRKKRRLESEC---SCGSSSPLRKKKKSVKKHRRD---RSDSGSRRK 221
K + GG RR +K R+ +E S G R+K + R +S SG
Sbjct: 441 KSRSGGGKKPRRRGQKARQKAAEAGAESRGDKKQGRQKASAAGTKSRGGGLKSHSGKNLW 500
Query: 222 RRHRSRSSKCKRKE----KNKEKKRPHTESPGRRSHRHSSGSSHS--------PSLSSHY 269
RR + + ++ K++ +K+P + P + G S S +SH
Sbjct: 501 RRGQKAEAAGEKATAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHG 560
Query: 270 SDSRSPSR----LSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAH- 324
SR P+ + R G + P + + R+G G+++
Sbjct: 561 GGGNKQSRGGGGNKPRQWGQTAAAAKTRGGGDKQPGWQKAAAGVTKSRSGDGGKKAWRQK 620
Query: 325 -GGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPR-SAPSSQGRGGRAAGG 382
G + P + +KA A T +RG PR P++ G AA
Sbjct: 621 AAGTGAKSRKKPWRRGQKDAAAAEKAWATGAT--SRGSGGKQPRWQKPAAAGSESSAAAA 678
Query: 383 AGR----RRRRRRRRRRSRSSASA-------PRRRGRRRPRPAPPRGSSRSLSRARSSSD 431
G+ R++ RRRR +SR P +R ++PR RG + SR +
Sbjct: 679 VGQEAEARKKPRRRRAKSRGDGGQNAAVGINPWQRRGKKPRLGKSRGGGGAKSRGSGGAK 738
Query: 432 S-GSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSR 490
S GSG G + + + HGG G AK R R GG + +S +
Sbjct: 739 SRGSGGAKSRSGKKAAASKSHGGGG--AKRR-----------------RGGGAKSRSGEK 779
Query: 491 --SPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSR 532
+ G + + + P + +SR + KKPL R
Sbjct: 780 AVTAGGQKAAAAGGKKPPRVKSRGG----RGQKAAAGGKKPLRR 819
Score = 62.4 bits (150), Expect = 1e-09
Identities = 111/510 (21%), Positives = 188/510 (36%), Gaps = 89/510 (17%)
Query: 207 KKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLS 266
KK RR ++ +G ++ R + + KE ++ ++ G + G + +
Sbjct: 57 KKLRRQKAAAGGKKARLRGQKGAVA-----GKEARQHWQKAAGAGGAENRGGGEQKAAAA 111
Query: 267 SHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSG-QRSGAHG 325
++S K R G+K + +GS+ P + +N G+G Q++ A
Sbjct: 112 G----TKSLGGRGRKPRRRGQKAAA---TGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAA 164
Query: 326 GRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGR 385
G P K ++ + R + P RG +S R +GR A G+
Sbjct: 165 GVKSQGGEKPQKAAAAGAKSR-----SGKKPRRRGAKS---RGDEDKKGRQREAKSRFGK 216
Query: 386 RRRRRRR--RRRSRSSASAPRRRG--------RRRPRPAPPRGSSRSLSRARSSSD---- 431
R RR+ RR ++ A RRG RRR + A G SR + ++R D
Sbjct: 217 TRGGRRKKHRRPKPAAGGAKSRRGGGKKPQKQRRRGQKAATGGKSR-VGKSRGGGDKKLR 275
Query: 432 ---------SGSGRGAPGPGPEPGSERGHGGHGKRA----------KERPPRARPASTSP 472
RGA G +P + +G GG G ++ + PR R +
Sbjct: 276 RQGQNAALAGAKRRGAATAGEKPAA-KGRGGRGPKSLGGQNPRWGRGGKKPRRRGQKATK 334
Query: 473 SPGAHGRRG----------GPEGKSSSRSPGPHPRSWSSSRSPSKSRS-------RSAEK 515
+ A +RG G + + R G PR +S + +KSR R A++
Sbjct: 335 AAAAGTKRGGGGQQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKR 394
Query: 516 RPHSPS-------RSPSPKKPLSRDK-DGEGRARHSEAEATRAR-RRSRSYSPIRKRRRD 566
R R + K P ++ + G + R +A ++R +SRS + RRR
Sbjct: 395 RGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRG 454
Query: 567 SPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHS-----RSPSPGHSHGSYS 621
+ + A R +S++ S +SHS R + G +
Sbjct: 455 QKARQKAAE-AGAESRGDKKQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQKAEAAGEKA 513
Query: 622 SRSHGTRSRTRSPSRTPSPSYHSRSSSESG 651
+ + G +SR R R P+ S G
Sbjct: 514 TAA-GAKSRGRKQPRRQKPAVAGAKSRVGG 542
Score = 54.7 bits (130), Expect = 3e-07
Identities = 67/316 (21%), Positives = 113/316 (35%), Gaps = 22/316 (6%)
Query: 159 WSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPL-----RKKKKSVKKHRRDR 213
W + +K G R RK+ R + G+ S + R+++K+V
Sbjct: 500 WRRGQKAEAAGEKATAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSH 559
Query: 214 SDSGSRRKRRHRSRSSK------CKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSS 267
G+++ R + K + K+P + + SG +
Sbjct: 560 GGGGNKQSRGGGGNKPRQWGQTAAAAKTRGGGDKQPGWQKAAAGVTKSRSGDGGKKAWRQ 619
Query: 268 HYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSP--QRNGGSGQRSGAHG 325
+ + + SR P R G+K + + + S GSG P Q+ +G S A
Sbjct: 620 KAAGTGAKSRKKPWRR--GQKDAAAAEKAWATGATSRGSGGKQPRWQKPAAAGSESSAAA 677
Query: 326 --GRPGSAHSPPDKPSSPSPRVRDKAAAAAPTP-PARGKESPSPRSAPSSQGRGGRAAGG 382
G+ A P + + S + AA P RGK+ PR S+G GG + G
Sbjct: 678 AVGQEAEARKKPRRRRAKSRGDGGQNAAVGINPWQRRGKK---PRLG-KSRGGGGAKSRG 733
Query: 383 AGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPG 442
+G + R +SRS A + RG + +G + A G
Sbjct: 734 SGGAKSRGSGGAKSRSGKKAAASKSHGGGGAKRRRGGGAKSRSGEKAVTAGGQKAAAAGG 793
Query: 443 PEPGSERGHGGHGKRA 458
+P + GG G++A
Sbjct: 794 KKPPRVKSRGGRGQKA 809
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 91.3 bits (225), Expect = 3e-18
Identities = 121/455 (26%), Positives = 179/455 (39%), Gaps = 68/455 (14%)
Query: 169 KKKKKKKGGHRRSRKKRR----LESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRH 224
K + K++ HR +KK + + E + S S RKK KS K + + + +
Sbjct: 185 KSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSKSPTL 244
Query: 225 RSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRD 284
R RS + K ++ + E + R S + SRSP L K +D
Sbjct: 245 RRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKD 304
Query: 285 EGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPR 344
R++ S+ RS + SP ++ SG+ + + RPG SP + SP PR
Sbjct: 305 --RRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPG--RSPKRRSLSPKPR 360
Query: 345 VRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPR 404
+ + + + R K+S SP S S GR RA + R+RR RRR S+PR
Sbjct: 361 DKSRRSRSPLLNDRRSKQSKSP-SRTLSPGR--RAKSRSLERKRREPERRR----LSSPR 413
Query: 405 RRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPR 464
R PR S R RS S R +P R + R P
Sbjct: 414 TR---------PRDDILS-RRERSKDASPINRWSP----------------TRRRSRSP- 446
Query: 465 ARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSP 524
R S SP RS P RS S R RSRS +R SRS
Sbjct: 447 IRRRSRSP---------------LRRSRSPRRRSRSPRRRDRGRRSRSRLRR---RSRSR 488
Query: 525 SPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRK---RRRDSPSFMEPRRITSARK 581
++ SR K E + + S +E + + S S + D + +E RRI R+
Sbjct: 489 GGRRRRSRSKVKEDKFKGSLSEGMKVEQESSSDDNLEDFDVEEEDEEALIEQRRI--QRQ 546
Query: 582 RPIPYYRPSPSSSSSCLSSDYS---TRSHSRSPSP 613
+ Y+ S+ + S+ S + + +RSPSP
Sbjct: 547 AIVQKYKYLAEDSNMSVPSEPSSPQSSTRTRSPSP 581
Score = 79.7 bits (195), Expect = 8e-15
Identities = 82/298 (27%), Positives = 123/298 (41%), Gaps = 28/298 (9%)
Query: 155 RTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSS----SPLRKKKKSVKKHR 210
+++ + S SP +++ ++K G RS +++ E S SP+ + +S + +
Sbjct: 231 KSQDQARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGK 290
Query: 211 RDRSD---SGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSS 267
+ RS G + RR RS+ K KR E +KEKK + S S + + S P
Sbjct: 291 KSRSPVDLRGKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPG--- 347
Query: 268 HYSDSRSPSR--LSPKHRDEGRKTGS-----QRSSGSRSPSPSGGSGWGSPQRNGGSGQR 320
RSP R LSPK RD+ R++ S +RS S+SPS + G + R+ +R
Sbjct: 348 -----RSPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRR 402
Query: 321 SGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESP------SPRSAPSSQG 374
P D S R +D + +P R SP SP S
Sbjct: 403 EPERRRLSSPRTRPRDDILSRRERSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRSPR 462
Query: 375 RGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDS 432
R R+ R RR R R RR S RRR R + + +GS + S S
Sbjct: 463 RRSRSPRRRDRGRRSRSRLRRRSRSRGGRRRRSRSKVKEDKFKGSLSEGMKVEQESSS 520
Score = 78.2 bits (191), Expect = 2e-14
Identities = 122/494 (24%), Positives = 183/494 (37%), Gaps = 68/494 (13%)
Query: 170 KKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSS 229
+ KKKK HR KK + SE K K KKH+R S ++ ++ +
Sbjct: 42 RHKKKKHKHRSKHKKHKHSSE---EDKDKKHKHKHKHKKHKRKEIIDASDKEGMSPAKRT 98
Query: 230 KCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPS---LSSHYSDSRSPSRLSPKHRDEG 286
K ++ ++ + G S L + S S + K R+
Sbjct: 99 KLDDLALLEDLEKQRALIKAELDNELMEGKVQSGMGLILQGYESGSEEEGEIHEKARNGN 158
Query: 287 RKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVR 346
R S RSS ++ + + +R+ + H + + + R +
Sbjct: 159 R--SSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRHRSDKKKSKGGIEIVKEKTTRSK 216
Query: 347 DKAAAAAPTPPARGK------ESPSPRSAPSSQGRGGRAAGGAG------RRRRRRRRRR 394
K + +P R K +S SP SQ + G+A + + + R++
Sbjct: 217 SKERKKSKSPSKRSKSQDQARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKK 276
Query: 395 RSRSSASAPRRRGRRRPRPAPPRGSS---RSLSRARSSSDSGSGRGAPGPGPEPGSERGH 451
+ S R RG++ P RG S RS S+ R S S + + P P +
Sbjct: 277 SPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKSKRSETDK-EKKPIKSPSKDASS 335
Query: 452 GGHGKRAKERPPRA-RPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPS---- 506
G + RP R+ + S SP P RR SRSP + R S+SPS
Sbjct: 336 GKENRSPSRRPGRSPKRRSLSPKPRDKSRR--------SRSPLLNDRRSKQSKSPSRTLS 387
Query: 507 ---KSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARR----RSRSYSP 559
+++SRS E++ P R P +R +D R +A+ R R RS SP
Sbjct: 388 PGRRAKSRSLERKRREPERR-RLSSPRTRPRDDILSRRERSKDASPINRWSPTRRRSRSP 446
Query: 560 IRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGS 619
IR+R R SP RR S R+R S S D RS SR S G
Sbjct: 447 IRRRSR-SPL----RRSRSPRRR-----------SRSPRRRDRGRRSRSRLRRRSRSRG- 489
Query: 620 YSSRSHGTRSRTRS 633
G R R+RS
Sbjct: 490 ------GRRRRSRS 497
Score = 73.9 bits (180), Expect = 4e-13
Identities = 118/488 (24%), Positives = 182/488 (37%), Gaps = 41/488 (8%)
Query: 189 SECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRK-EKNKEKKRPHTES 247
SE S + + +S KH R + ++K +HRS+ K K E++K+KK H
Sbjct: 20 SEKSINEENGEVSEDQSQNKHSRHK-----KKKHKHRSKHKKHKHSSEEDKDKKHKHKHK 74
Query: 248 PGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSG 307
+ + +S +S L + ++ + G G
Sbjct: 75 HKKHKRKEIIDASDKEGMSPAKRTKLDDLALLEDLEKQRALIKAELDNELMEGKVQSGMG 134
Query: 308 WGSPQRNGGSGQRSGAHG-GRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSP 366
GS + H R G+ S + + D +R KE
Sbjct: 135 LILQGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRH 194
Query: 367 RSAPSSQGRGGR--AAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLS 424
RS + +GG R + + R++ +S S S + + R+ P R S +
Sbjct: 195 RS-DKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSKSPTLRRRSQEKIG 253
Query: 425 RARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPE 484
+ARS +D ++ + R+++R ++R + + RR +
Sbjct: 254 KARSPTDDKVK--IEDKSKSKDRKKSPIINESRSRDRGKKSR-SPVDLRGKSKDRRSRSK 310
Query: 485 GKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHS--PSRSPSPK--KPLSRDKDGEGRA 540
+ S RS + +SPSK S E R S P RSP + P RDK R+
Sbjct: 311 ERKSKRSETDKEKK--PIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKSRRSRS 368
Query: 541 -----RHSEAEATRAR-----RRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIP--YYR 588
R S+ + +R RR++S S RKRR E RR++S R RP R
Sbjct: 369 PLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREP-----ERRRLSSPRTRPRDDILSR 423
Query: 589 PSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTP----SPSYHS 644
S +S ++ TR SRSP S S RS R R+RSP R S S
Sbjct: 424 RERSKDASPINRWSPTRRRSRSPIRRRSR-SPLRRSRSPRRRSRSPRRRDRGRRSRSRLR 482
Query: 645 RSSSESGG 652
R S GG
Sbjct: 483 RRSRSRGG 490
>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
Length = 1512
Score = 90.9 bits (224), Expect = 3e-18
Identities = 117/381 (30%), Positives = 148/381 (38%), Gaps = 75/381 (19%)
Query: 334 PPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRR 393
PP P AAAAA + SP P RG R AGG R++RR
Sbjct: 53 PPPPPLLFLAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGG------RQKRR 106
Query: 394 RRSRSSASAPRRRGRRRPRPAPPRGSSRS-----------------------LSRARSSS 430
R R+ A +RR P+P G S L A +++
Sbjct: 107 RGPRAGQEAEKRRVFSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAAT 166
Query: 431 DSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAH-------GRRGGP 483
+ + G G G P S G G+ ++ RP R R +S+ S H G+RGG
Sbjct: 167 AATAAGGTGGSGGSPASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGS 226
Query: 484 EGKSSSRSPGPH--------PRSWSSSRSPSKSRSRSAEKRPHSP----------SRSPS 525
E S SRS H +S SSS S + +S SA S SR+ S
Sbjct: 227 EA-SKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKS 285
Query: 526 PKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRP-- 583
K+P S K+ R + E +A RR RS SP+ R DSP + +RK P
Sbjct: 286 SKEPPSAYKEPPKAYREDKTE-PKAYRRRRSLSPL-GGRDDSPVSHRASQSLRSRKSPSP 343
Query: 584 -----IPYYR---PSPSSSSSCLSSDYSTRSHSR-----SPSPGHSHGSYSSRSHGT--- 627
PY R SPS S S YS S SPSP S SRS +
Sbjct: 344 AGGGSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVL 403
Query: 628 RSRTRSPSRTPSPSYHSRSSS 648
R +S SR+P S HSRS S
Sbjct: 404 RRSGKSRSRSPYSSRHSRSRS 424
Score = 75.1 bits (183), Expect = 2e-13
Identities = 114/485 (23%), Positives = 180/485 (37%), Gaps = 71/485 (14%)
Query: 192 SCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRR 251
SC S P + K+ + RR +G R+KRR R+ + K + +P + G
Sbjct: 79 SCFSPGPPLEVKRLARGKRR----AGGRQKRRRGPRAGQEAEKRRVFSLPQPQQDGGGGA 134
Query: 252 SHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSP 311
SSG +P + Y D S S ++G G ++ + + + G GSP
Sbjct: 135 ----SSGGGVTPLV--EYEDVSSQS-------EQGLLLGGASAATAATAAGGTGGSGGSP 181
Query: 312 QRNGGSGQRSGAHGGRP---GSAHSPPDKPSSPSPRVRDKAAAAAPTPPAR------GKE 362
+ G+ +R RP + S K R RD + +R G+E
Sbjct: 182 ASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSGEE 241
Query: 363 SPSPRSAPSSQGRGGR------AAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPA-- 414
+ SS GGR + + R+ R + RSR+ +S + P A
Sbjct: 242 RAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYR 301
Query: 415 PPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSP 474
+ ++ R RS S G +P S R P +R SPSP
Sbjct: 302 EDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSPSP 361
Query: 475 GAHGRRGGPEGKSSSR-------SPGPH-PRSWSSSRSP--------SKSRSRSAEKRPH 518
+ RR P S SP P+ SW SRSP KSRSRS H
Sbjct: 362 --YSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSSRH 419
Query: 519 SPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITS 578
S SR SR + R+RHS + +S + + K ++ + E R
Sbjct: 420 SRSR--------SRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAA--EAARAAE 469
Query: 579 ARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSH--GSYSSRSHGTRSRTRSPSR 636
A K + ++ ++ ++ + S++ +P+ G++ S S +H +
Sbjct: 470 AAK-------AAEATKAAEAAAKAAKASNTSTPTKGNTETSASASQTNHVKDVKKIKIEH 522
Query: 637 TPSPS 641
PSPS
Sbjct: 523 APSPS 527
Score = 71.6 bits (174), Expect = 2e-12
Identities = 105/411 (25%), Positives = 149/411 (36%), Gaps = 77/411 (18%)
Query: 213 RSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDS 272
R GS R+ R RSS + KE+++E +R R R S +S S S SH +
Sbjct: 189 RRGEGSERRPRRDRRSSSGRSKERHREHRR-------RDGQRGGSEASKSRSRHSHSGEE 241
Query: 273 RSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAH 332
R+ E K+GS SSG R S S S S +++ + S AH R S+
Sbjct: 242 RA----------EVAKSGSSSSSGGRRKSASATSSSSSSRKD----RDSKAHRSRTKSSK 287
Query: 333 SPPDKPSSPSPRVRD-----KAAAAAPTPPARGKESPSPRSAPSSQGRGGR-----AAGG 382
PP P R+ KA + G SP S +SQ R A GG
Sbjct: 288 EPPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGG 347
Query: 383 AGRRRRR--------RRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGS 434
+ RR RRR S S S+ R G P P SS S R+RS
Sbjct: 348 SSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPY----SSSSWRRSRSPYSPVL 403
Query: 435 GRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGP 494
R P S R H R + R+R +S SPS
Sbjct: 404 RRSGKSRSRSPYSSR-HSRSRSRHRLSRSRSRHSSISPS--------------------- 441
Query: 495 HPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRS 554
+ + S +AE + +R+ + K E A + A +A + S
Sbjct: 442 ---------TLTLKSSLAAELNKNKKARAAEAARAAEAAKAAE--ATKAAEAAAKAAKAS 490
Query: 555 RSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTR 605
+ +P + S S + + +K I + PSPSS + + T+
Sbjct: 491 NTSTPTKGNTETSASASQTNHVKDVKKIKIE-HAPSPSSGGTLKNDKAKTK 540
Score = 52.0 bits (123), Expect = 2e-06
Identities = 78/339 (23%), Positives = 120/339 (35%), Gaps = 53/339 (15%)
Query: 149 RGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESE-------CSCGSSSPLRK 201
R R R+ S +++ ++GG S+ + R GSSS
Sbjct: 197 RPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSGEERAEVAKSGSSSSSGG 256
Query: 202 KKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSH 261
++KS S R + HRSR+ + +KE + E P +++R
Sbjct: 257 RRKSASATSSSSSSRKDRDSKAHRSRT------KSSKEPPSAYKEPP--KAYREDKTEPK 308
Query: 262 SPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRS 321
+ Y RS S L + SQ +SPSP+GG
Sbjct: 309 A------YRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGG---------------- 346
Query: 322 GAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAG 381
G P S P + SP R R + + + G SPSP S SS R R+
Sbjct: 347 ---GSSPYSRRLP--RSPSPYSRRRSPSYSRHSSYERGGDVSPSPYS--SSSWRRSRSPY 399
Query: 382 GAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLS------RARSSSDSGSG 435
RR + RSRS S+ R R R R + R S+S ++ +++
Sbjct: 400 SP---VLRRSGKSRSRSPYSSRHSRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKN 456
Query: 436 RGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSP 474
+ A +E +A E +A AS + +P
Sbjct: 457 KKARAAEAARAAEAAKAAEATKAAEAAAKAAKASNTSTP 495
Score = 48.1 bits (113), Expect = 2e-05
Identities = 92/381 (24%), Positives = 124/381 (32%), Gaps = 96/381 (25%)
Query: 366 PRSAPSSQGRGGRAAGGAGRRRRRRRRRR---RSRSSASAPRRRGRRRPRPAPP-----R 417
P S+ ++ G GG + + RR+RRR + P + + P PP
Sbjct: 2 PSSSDTALGGGGGLSWAEKKLEERRKRRRFLSPQQPPLLLPLLQPQLLQPPPPPPPLLFL 61
Query: 418 GSSRSLSRARSSSDSGSGRGAPGPGPE----PGSERGHGGHGKRAKERPPRA------RP 467
+ + + A +++ + S +PGP E +R GG KR R PRA R
Sbjct: 62 AAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKR--RRGPRAGQEAEKRR 119
Query: 468 ASTSPSPGAHGRRG-----------------------------------------GPEGK 486
+ P P G G G G
Sbjct: 120 VFSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGSGG 179
Query: 487 SSSRSPGPHPRSWSSSRSP----------SKSRSRSAEKRPHSPSRSPSPKKPLSRDKDG 536
S + S G R S R P SK R R +R S + K G
Sbjct: 180 SPASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSG 239
Query: 537 EGR---ARHSEAEATRARRRSRS-YSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPS 592
E R A+ + ++ RR+S S S R+D S R S+++ P Y P +
Sbjct: 240 EERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKA 299
Query: 593 SSSSCLSSDYSTRSHSRSPSPGHSHGSYSSR-SHGTRSR-----------------TRSP 634
R S SP G S R S RSR RSP
Sbjct: 300 YREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSP 359
Query: 635 ---SRTPSPSYHSRSSSESGG 652
SR SPSY SS E GG
Sbjct: 360 SPYSRRRSPSYSRHSSYERGG 380
>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
Length = 1452
Score = 90.9 bits (224), Expect = 3e-18
Identities = 117/381 (30%), Positives = 148/381 (38%), Gaps = 75/381 (19%)
Query: 334 PPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRR 393
PP P AAAAA + SP P RG R AGG R++RR
Sbjct: 53 PPPPPLLFLAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGG------RQKRR 106
Query: 394 RRSRSSASAPRRRGRRRPRPAPPRGSSRS-----------------------LSRARSSS 430
R R+ A +RR P+P G S L A +++
Sbjct: 107 RGPRAGQEAEKRRVFSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAAT 166
Query: 431 DSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAH-------GRRGGP 483
+ + G G G P S G G+ ++ RP R R +S+ S H G+RGG
Sbjct: 167 AATAAGGTGGSGGSPASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGS 226
Query: 484 EGKSSSRSPGPH--------PRSWSSSRSPSKSRSRSAEKRPHSP----------SRSPS 525
E S SRS H +S SSS S + +S SA S SR+ S
Sbjct: 227 EA-SKSRSRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKS 285
Query: 526 PKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRP-- 583
K+P S K+ R + E +A RR RS SP+ R DSP + +RK P
Sbjct: 286 SKEPPSAYKEPPKAYREDKTE-PKAYRRRRSLSPL-GGRDDSPVSHRASQSLRSRKSPSP 343
Query: 584 -----IPYYR---PSPSSSSSCLSSDYSTRSHSR-----SPSPGHSHGSYSSRSHGT--- 627
PY R SPS S S YS S SPSP S SRS +
Sbjct: 344 AGGGSSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVL 403
Query: 628 RSRTRSPSRTPSPSYHSRSSS 648
R +S SR+P S HSRS S
Sbjct: 404 RRSGKSRSRSPYSSRHSRSRS 424
Score = 75.1 bits (183), Expect = 2e-13
Identities = 114/485 (23%), Positives = 180/485 (37%), Gaps = 71/485 (14%)
Query: 192 SCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRR 251
SC S P + K+ + RR +G R+KRR R+ + K + +P + G
Sbjct: 79 SCFSPGPPLEVKRLARGKRR----AGGRQKRRRGPRAGQEAEKRRVFSLPQPQQDGGGGA 134
Query: 252 SHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSP 311
SSG +P + Y D S S ++G G ++ + + + G GSP
Sbjct: 135 ----SSGGGVTPLV--EYEDVSSQS-------EQGLLLGGASAATAATAAGGTGGSGGSP 181
Query: 312 QRNGGSGQRSGAHGGRP---GSAHSPPDKPSSPSPRVRDKAAAAAPTPPAR------GKE 362
+ G+ +R RP + S K R RD + +R G+E
Sbjct: 182 ASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSGEE 241
Query: 363 SPSPRSAPSSQGRGGR------AAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPA-- 414
+ SS GGR + + R+ R + RSR+ +S + P A
Sbjct: 242 RAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAYR 301
Query: 415 PPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSP 474
+ ++ R RS S G +P S R P +R SPSP
Sbjct: 302 EDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSPSP 361
Query: 475 GAHGRRGGPEGKSSSR-------SPGPH-PRSWSSSRSP--------SKSRSRSAEKRPH 518
+ RR P S SP P+ SW SRSP KSRSRS H
Sbjct: 362 --YSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSSRH 419
Query: 519 SPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITS 578
S SR SR + R+RHS + +S + + K ++ + E R
Sbjct: 420 SRSR--------SRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAA--EAARAAE 469
Query: 579 ARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSH--GSYSSRSHGTRSRTRSPSR 636
A K + ++ ++ ++ + S++ +P+ G++ S S +H +
Sbjct: 470 AAK-------AAEATKAAEAAAKAAKASNTSTPTKGNTETSASASQTNHVKDVKKIKIEH 522
Query: 637 TPSPS 641
PSPS
Sbjct: 523 APSPS 527
Score = 71.6 bits (174), Expect = 2e-12
Identities = 105/411 (25%), Positives = 149/411 (36%), Gaps = 77/411 (18%)
Query: 213 RSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDS 272
R GS R+ R RSS + KE+++E +R R R S +S S S SH +
Sbjct: 189 RRGEGSERRPRRDRRSSSGRSKERHREHRR-------RDGQRGGSEASKSRSRHSHSGEE 241
Query: 273 RSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAH 332
R+ E K+GS SSG R S S S S +++ + S AH R S+
Sbjct: 242 RA----------EVAKSGSSSSSGGRRKSASATSSSSSSRKD----RDSKAHRSRTKSSK 287
Query: 333 SPPDKPSSPSPRVRD-----KAAAAAPTPPARGKESPSPRSAPSSQGRGGR-----AAGG 382
PP P R+ KA + G SP S +SQ R A GG
Sbjct: 288 EPPSAYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGG 347
Query: 383 AGRRRRR--------RRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGS 434
+ RR RRR S S S+ R G P P SS S R+RS
Sbjct: 348 SSPYSRRLPRSPSPYSRRRSPSYSRHSSYERGGDVSPSPY----SSSSWRRSRSPYSPVL 403
Query: 435 GRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGP 494
R P S R H R + R+R +S SPS
Sbjct: 404 RRSGKSRSRSPYSSR-HSRSRSRHRLSRSRSRHSSISPS--------------------- 441
Query: 495 HPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRS 554
+ + S +AE + +R+ + K E A + A +A + S
Sbjct: 442 ---------TLTLKSSLAAELNKNKKARAAEAARAAEAAKAAE--ATKAAEAAAKAAKAS 490
Query: 555 RSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTR 605
+ +P + S S + + +K I + PSPSS + + T+
Sbjct: 491 NTSTPTKGNTETSASASQTNHVKDVKKIKIE-HAPSPSSGGTLKNDKAKTK 540
Score = 52.0 bits (123), Expect = 2e-06
Identities = 78/339 (23%), Positives = 120/339 (35%), Gaps = 53/339 (15%)
Query: 149 RGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESE-------CSCGSSSPLRK 201
R R R+ S +++ ++GG S+ + R GSSS
Sbjct: 197 RPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSGEERAEVAKSGSSSSSGG 256
Query: 202 KKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSH 261
++KS S R + HRSR+ + +KE + E P +++R
Sbjct: 257 RRKSASATSSSSSSRKDRDSKAHRSRT------KSSKEPPSAYKEPP--KAYREDKTEPK 308
Query: 262 SPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRS 321
+ Y RS S L + SQ +SPSP+GG
Sbjct: 309 A------YRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGG---------------- 346
Query: 322 GAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAG 381
G P S P + SP R R + + + G SPSP S SS R R+
Sbjct: 347 ---GSSPYSRRLP--RSPSPYSRRRSPSYSRHSSYERGGDVSPSPYS--SSSWRRSRSPY 399
Query: 382 GAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLS------RARSSSDSGSG 435
RR + RSRS S+ R R R R + R S+S ++ +++
Sbjct: 400 SP---VLRRSGKSRSRSPYSSRHSRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKN 456
Query: 436 RGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSP 474
+ A +E +A E +A AS + +P
Sbjct: 457 KKARAAEAARAAEAAKAAEATKAAEAAAKAAKASNTSTP 495
Score = 48.1 bits (113), Expect = 2e-05
Identities = 92/381 (24%), Positives = 124/381 (32%), Gaps = 96/381 (25%)
Query: 366 PRSAPSSQGRGGRAAGGAGRRRRRRRRRR---RSRSSASAPRRRGRRRPRPAPP-----R 417
P S+ ++ G GG + + RR+RRR + P + + P PP
Sbjct: 2 PSSSDTALGGGGGLSWAEKKLEERRKRRRFLSPQQPPLLLPLLQPQLLQPPPPPPPLLFL 61
Query: 418 GSSRSLSRARSSSDSGSGRGAPGPGPE----PGSERGHGGHGKRAKERPPRA------RP 467
+ + + A +++ + S +PGP E +R GG KR R PRA R
Sbjct: 62 AAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKR--RRGPRAGQEAEKRR 119
Query: 468 ASTSPSPGAHGRRG-----------------------------------------GPEGK 486
+ P P G G G G
Sbjct: 120 VFSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGSGG 179
Query: 487 SSSRSPGPHPRSWSSSRSP----------SKSRSRSAEKRPHSPSRSPSPKKPLSRDKDG 536
S + S G R S R P SK R R +R S + K G
Sbjct: 180 SPASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSG 239
Query: 537 EGR---ARHSEAEATRARRRSRS-YSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPS 592
E R A+ + ++ RR+S S S R+D S R S+++ P Y P +
Sbjct: 240 EERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKA 299
Query: 593 SSSSCLSSDYSTRSHSRSPSPGHSHGSYSSR-SHGTRSR-----------------TRSP 634
R S SP G S R S RSR RSP
Sbjct: 300 YREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSP 359
Query: 635 ---SRTPSPSYHSRSSSESGG 652
SR SPSY SS E GG
Sbjct: 360 SPYSRRRSPSYSRHSSYERGG 380
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 87.0 bits (214), Expect = 5e-17
Identities = 143/604 (23%), Positives = 216/604 (35%), Gaps = 79/604 (13%)
Query: 72 EMMEEQGYSEEEIRQKVGTFRQMLMEKEGVLTREDRPGGHIVAETPRLTEGAEPGLEYAP 131
E E +GYS ++ G +KE T R G + + RL E
Sbjct: 157 EKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKE-------- 208
Query: 132 FDDDDGPVDCDCPASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESEC 191
D+++G D + + G T+ W S GH + + E+
Sbjct: 209 -DNEEGVYDYE--------NTGRMTQKWIQS--------------GHIATYYTIQDEAYD 245
Query: 192 SCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRR 251
+ S L ++ K ++ R S S+ R +S+ +E K+R S R
Sbjct: 246 TTDS---LLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRD 302
Query: 252 SHRHSSGSS-HSPSLS-----SHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGG 305
S HS S HS S S S + SR SR P+ DE R + + SR
Sbjct: 303 SEGHSEDSERHSGSASRNHHGSAWEQSRDGSR-HPRSHDEDRASHGHSADSSRQSGTRHA 361
Query: 306 SGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARG----K 361
Q Q + G R GS H S S R +A++A RG +
Sbjct: 362 ETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQ 421
Query: 362 ESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSR 421
S S + +S + G AG R++ + R RS R GR GSS
Sbjct: 422 ASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSG----ERSGR--------SGSSL 469
Query: 422 SLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRG 481
DS GR G GS R P GR+G
Sbjct: 470 YQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQG 529
Query: 482 GPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGR-- 539
+S +RS S S + S+ RS S SRS S ++ + ++ G+G
Sbjct: 530 SHHEQSVNRSGHS-----GSHHSHTTSQGRSDASHGQSGSRSAS-RQTRNEEQSGDGTRH 583
Query: 540 --ARH----SEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSS 593
+RH S+A+++R + + S + R+ S + + + S S
Sbjct: 584 SGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASR 643
Query: 594 SSSCLSSDYSTRSHSRSP------SPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSS 647
+ S+ +R SR P GH H + SSR GTR T++ S + S H ++
Sbjct: 644 NHHG-SAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTR-HTQNSSSGQAASSHEQAR 701
Query: 648 SESG 651
S +G
Sbjct: 702 SSAG 705
Score = 83.2 bits (204), Expect = 7e-16
Identities = 127/518 (24%), Positives = 185/518 (35%), Gaps = 52/518 (10%)
Query: 150 GHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKH 209
GH G H +S S + + + R++R + + S S S +
Sbjct: 3458 GHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQ-SGDGSRHSWSHHHEASTQADSS 3516
Query: 210 RRDRS----DSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSS------GS 259
R +S +G R R S S+ + + E + S R +HR S+ GS
Sbjct: 3517 RHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASR-NHRGSAQEQSRDGS 3575
Query: 260 SHSPSLSSHYSD------SRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQR 313
H +SH+ D S SR S H E G SS ++ S +G Q+
Sbjct: 3576 RHP---TSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQ 3632
Query: 314 NGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAA--APTPPARGKESPSPRSAPS 371
+ S + SG G+ SA S + D + + T P
Sbjct: 3633 SADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSH 3692
Query: 372 SQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSD 431
+ GR+AG +GR + S SA GR P +GS +R SS
Sbjct: 3693 QESTRGRSAGRSGRSGSFLYQVSTHEQSESA---HGRAGPSTGGRQGSRHEQARD-SSRH 3748
Query: 432 SGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPS-PGAHGRRGGPEGKSSSR 490
S S G PGS RG G G ++ R+ + + S + GR G+S SR
Sbjct: 3749 SASQEGQDTIRGHPGSRRG-GRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSR 3807
Query: 491 SPGPHPRSWSSSRSPSK-------SRSRSAEKRPHSPS---------RSPSPKKPLSRDK 534
S R+ S S+ S A+ HS S RS +S+D
Sbjct: 3808 SASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDS 3867
Query: 535 DGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFM-EPRRITSARKRPIPYYRPSPSS 593
D E SE + A R S R++ RD R T++ + P S ++
Sbjct: 3868 DSEAYPEDSERRSESASRNHHGSS--REQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTA 3925
Query: 594 SS----SCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGT 627
S LS D + S +S HS SY +S GT
Sbjct: 3926 KEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGT 3963
Score = 82.8 bits (203), Expect = 9e-16
Identities = 124/530 (23%), Positives = 186/530 (35%), Gaps = 57/530 (10%)
Query: 149 RGHRGYRTKHWSSSSASPPPKKKKKKKG---------GHRRSRKKRRLESECSCGSSS-P 198
RGHRG S S + G H+ S + R E GSS
Sbjct: 412 RGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQ 471
Query: 199 LRKKKKSVKKHRRDRSDSGSRRKRRHRSR--SSKCKRKEKNKEKKRPHTESP--GRRSHR 254
+ ++ H R + +G R+ H SS+ ++ ++ R H S GR+
Sbjct: 472 VSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSH 531
Query: 255 HSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRN 314
H + S SH+S + S R H G ++ S+++ G R+
Sbjct: 532 HEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQS--------GDGTRH 583
Query: 315 GGSGQRSGAHGGRPGSAHSPPDKPSSPSPRV-RDKAAAAAPTPPARGKESPSPR-SAPSS 372
GS + A S HS + S PR R++ ++ + ++G S R S +S
Sbjct: 584 SGS-RHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSAS 642
Query: 373 QGRGGRAAGGAGRRRRRRRRRRRSRS----SASAPRRRGRRRPRPAPPRGSSRSLSRARS 428
+ G A + R R R+ SA + R+ G R + + ++ S +ARS
Sbjct: 643 RNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARS 702
Query: 429 SSDS--GSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGK 486
S+ GS S GHG ++ R S + H +
Sbjct: 703 SAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSV 762
Query: 487 SSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAE 546
S G H +S S +R RS E+ RS S +S K E + H
Sbjct: 763 SGHGQAGHHQQSHQES-----ARDRSGER----SRRSGSFLYQVSTHKQSE--SSHGWTG 811
Query: 547 ATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRS 606
+ R+ + R R S S I R P SS + +S
Sbjct: 812 PSTGVRQGSHHEQARDNSRHSASQDGQDTI-----------RGHPGSSRRGRQGSHHEQS 860
Query: 607 HSRSPSPG--HSHGSYSSRSHGTR--SRTRSPSRTPSPSYHSRSSSESGG 652
RS G HSH + RS +R S +RS SRT SR S G
Sbjct: 861 VDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSG 910
Score = 81.3 bits (199), Expect = 3e-15
Identities = 126/525 (24%), Positives = 193/525 (36%), Gaps = 64/525 (12%)
Query: 150 GHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRK-KRRLESECSCGSSSPLRKKKKSVKK 208
GH G H +S S + + R++RK K+ + GS +
Sbjct: 1189 GHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSR 1248
Query: 209 HRR--DRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSH-----------RH 255
H + SGSR R S S+ E++ + + S R H RH
Sbjct: 1249 HSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRH 1308
Query: 256 SSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNG 315
+ H +DS SR S H E G SS ++ S G Q++
Sbjct: 1309 PGFHQEDRASHGHSADS---SRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSA 1365
Query: 316 GSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAA----AAAPTPPARGKESPSPRS-AP 370
S + SG + SA S +V + + + A G+ P +S
Sbjct: 1366 DSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKE 1425
Query: 371 SSQGRGGRAAGGAGRRRRRRRRRRRSRSS--ASAPRRRGRRRPRPAPPRGSSRSLSRARS 428
S++G+ G ++G + + +S S+ +AP GR+ R R SSR S
Sbjct: 1426 SARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSR-----HS 1480
Query: 429 SSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSS 488
+S G + RGH G + ++ + S G H P+G+S
Sbjct: 1481 ASQDGQ-----------DTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSD 1529
Query: 489 SRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSR--SPSPKKPLSRDKD-GEGRARHSEA 545
+ PRS S +++ +S + HS SR PS + SR G+G + S+
Sbjct: 1530 ASHGQSGPRSASRQ---TRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKT 1586
Query: 546 EATRARRRSRSYSPIRKRRRDSPSFME--PRRITSARKRPIPYYRPSPSSSSSCLSSDYS 603
+RR+ S S + RDS E RR SA + R S +
Sbjct: 1587 ----SRRQGSSVS----QDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSR------N 1632
Query: 604 TRSHSRSPSPGHSHGSYSSRSHGTR-SRTRSPSRTPSPSYHSRSS 647
RSH + H H + SSR GTR + T S + S +RSS
Sbjct: 1633 PRSHQEDRA-SHGHSAESSRQSGTRHAETSSGGQAASSQEQARSS 1676
Score = 80.9 bits (198), Expect = 3e-15
Identities = 129/532 (24%), Positives = 198/532 (37%), Gaps = 72/532 (13%)
Query: 150 GHRGYRTKHWSSSSASPPPKKKKK-----KKGGHRRSRKKR-RLESECSCGSSSP----L 199
GHRG ++S + + G H++S K+ R +S S G S +
Sbjct: 1386 GHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQV 1445
Query: 200 RKKKKSVKKHRRDRSDSGSRRKRRHRS--RSSKCKRKEKNKEKKRPHTESP--GRRSHRH 255
++S H + +G R+ RH SS+ + ++ R H S GR+ H
Sbjct: 1446 SSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYH 1505
Query: 256 SSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQ------------RSSGSRSPSPS 303
S H+S + R H G ++ S+ R SGSR PS
Sbjct: 1506 EQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPS 1565
Query: 304 GGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPS---SPSPRVRDKAAAAAPTPPARG 360
+G S G G+ +G+ R + D+ S S R ++A+ AR
Sbjct: 1566 TRAG-SSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSARE 1624
Query: 361 KESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAP-PRGS 419
+ R+ S Q RA+ G R+ R + +S+ + + R +P R
Sbjct: 1625 QSRHGSRNPRSHQ--EDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHG 1682
Query: 420 SRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGR 479
SR A SS+DSG+GR G G G +A + + + T S AHG+
Sbjct: 1683 SRHQQSADSSTDSGTGRRQ--DSSVVGDSGNRGSSGSQASDSEGHSEESDTQ-SVSAHGQ 1739
Query: 480 RGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGR 539
GPH +S S +R +S E+ RS S +S + E
Sbjct: 1740 ------------AGPHQQSHQES-----TRGQSGER----SGRSGSFLYQVSTHEQSES- 1777
Query: 540 ARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLS 599
A +T R+RSR ++ RDS SA + R P SS
Sbjct: 1778 AHGRTGPSTGGRQRSR-----HEQARDSSRH-------SASQEGQDTIRGHPGSSRGGRQ 1825
Query: 600 SDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESG 651
+ +S S G H +S+ SR +S SR S S +R+ +SG
Sbjct: 1826 GSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSR--SVSRQTRNEKQSG 1875
Score = 80.5 bits (197), Expect = 5e-15
Identities = 126/526 (23%), Positives = 184/526 (34%), Gaps = 71/526 (13%)
Query: 161 SSSASPPPKKKKKKKGGHRRS---------RKKRRLESECSCGSSSPLRKKKKSVKKHRR 211
S S S + +K+ G R S R S+ G SS R + +
Sbjct: 1861 SRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQ 1920
Query: 212 DRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPG-----RRSHRHSSGSSHSPSLS 266
D G S S+ E+ R + PG R H HS+ SS
Sbjct: 1921 DSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTR 1980
Query: 267 SHYSDSRSPSRLSPKHR--DEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAH 324
S SR + S + G + GS S S G G G S R H
Sbjct: 1981 HTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQ----ASSAVRDSGH 2036
Query: 325 GGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRS-APSSQGRGGRAAGGA 383
G GS S + S S + A+GK P +S S++G+ G ++G +
Sbjct: 2037 RGYSGSQASDSEGHSEDSD---------TQSVSAQGKAGPHQQSHKESARGQSGESSGRS 2087
Query: 384 GRRRRRRRRRRRSRSS--ASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGP 441
G + +S S+ SAP GR+ + SSR S ++ D+ G P
Sbjct: 2088 GSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRH-SASQEGQDTIRGHPGPSR 2146
Query: 442 GPEPGSER-------GHGGH-----GKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSS 489
G GS + GH G + + R + S S S + + +G S
Sbjct: 2147 GGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHS 2206
Query: 490 RSPGPHPRSWS-SSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEAT 548
S SW+ SSR + +S+ R P S +S+D D EG + SE
Sbjct: 2207 GSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGS-----SVSQDSDSEGHSEDSE---- 2257
Query: 549 RARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHS 608
RRS S S R S E R + P ++ S SS S H+
Sbjct: 2258 ---RRSGSAS-----RNHHGSAQEQSR--DGSRHPRSHHEDRAGHGHSAESSRQSGTHHA 2307
Query: 609 RSPSPGHSHGSY------SSRSHGTRSRTRSPSRTPSPSYHSRSSS 648
+ S G + S+ + HG+ + + S S H ++SS
Sbjct: 2308 ENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASS 2353
Score = 79.0 bits (193), Expect = 1e-14
Identities = 118/512 (23%), Positives = 189/512 (36%), Gaps = 81/512 (15%)
Query: 161 SSSASPPPKKKKKKKGGHRRSRKKR-------------RLESECSCGSSSPLRKKKKSVK 207
S SAS +K K+ G R S + ++ E S GS + + +
Sbjct: 1213 SRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQ 1272
Query: 208 KHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKR-PHTESPGRRSHRHSSGSSHSPSLS 266
+R S R SR+ +E++++ R P R SH HS+ SS
Sbjct: 1273 DSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSG-- 1330
Query: 267 SHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGG 326
+H+++S S + H ++ R + +R S G R S R H G
Sbjct: 1331 THHTESSSHGQAVSSH-EQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRG 1389
Query: 327 RPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRS-APSSQGRGGRAAGGAGR 385
GS + + S S + A G+ P +S S++G+ G ++G +
Sbjct: 1390 SSGSQVTNSEGHSEDSD---------TQSVSAHGQAGPHQQSHKESARGQSGESSGRSRS 1440
Query: 386 RRRRRRRRRRSRSS--ASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGP 443
+ +S S+ +AP GR+ R R SSR S+S G
Sbjct: 1441 FLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSR-----HSASQDGQD-------- 1487
Query: 444 EPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSR 503
+ RGH G + ++ + S G H P+G+S + PRS S
Sbjct: 1488 ---TIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQ- 1543
Query: 504 SPSKSRSRSAEKRPHSPSR--SPSPKKPLSRDKD-GEGRARHSEAEATRARRRSRSYSPI 560
+++ +S + HS SR PS + SR G+G + S+ +RR+ S S
Sbjct: 1544 --TRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKT----SRRQGSSVS-- 1595
Query: 561 RKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSY 620
+ RDS E S R+ S+ ++R+H S HGS
Sbjct: 1596 --QDRDSEGHSED----SERR------------------SESASRNHYGSAREQSRHGSR 1631
Query: 621 SSRSHGTRSRTRSPSRTPSPSYHSRSSSESGG 652
+ RSH + S S +R + S G
Sbjct: 1632 NPRSHQEDRASHGHSAESSRQSGTRHAETSSG 1663
Score = 77.4 bits (189), Expect = 4e-14
Identities = 117/494 (23%), Positives = 179/494 (36%), Gaps = 50/494 (10%)
Query: 176 GGHRRSRKK--RRLESECSCGSSSPLRK---KKKSVKKHRRDRSDSGSRRKRRHRSRSSK 230
G H++S ++ R E S S S L + ++S H R +G R++ RH
Sbjct: 1741 GPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRH------ 1794
Query: 231 CKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHR----DEG 286
E+ ++ R G+ + R GSS SHY S S S H +
Sbjct: 1795 ----EQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQE 1850
Query: 287 RKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSA-HSPPDKPSSPSPRV 345
R S+ SGSRS S + S + SG R R S+ HS + S PR
Sbjct: 1851 RSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRT 1910
Query: 346 -RDKAAAAAPTPPARGKESPSPR-SAPSSQGRGGRA----AGGAGRRRRRRRRRRRSRSS 399
R++ ++ + ++G S R S +S+ G A G+ R S
Sbjct: 1911 SRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHS 1970
Query: 400 ASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDS--GSGRGAPGPGPEPGSERGHGGHGKR 457
A + R+ G R + ++ S +ARSS+ GS S GHG
Sbjct: 1971 ADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSA 2030
Query: 458 AKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRP 517
++ R S + H + S+ GPH +S S +R +S E
Sbjct: 2031 VRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKES-----ARGQSGE--- 2082
Query: 518 HSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRIT 577
S RS S +S + E + H ++ + R+ Y + R S S I
Sbjct: 2083 -SSGRSGSFLYQVSTHEQSE--STHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTI- 2138
Query: 578 SARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRT 637
R P S + +S RS G H +S+ SR +S SR+
Sbjct: 2139 ----------RGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRS 2188
Query: 638 PSPSYHSRSSSESG 651
S + + S G
Sbjct: 2189 ASRKTYDKEQSGDG 2202
Score = 75.1 bits (183), Expect = 2e-13
Identities = 119/522 (22%), Positives = 187/522 (35%), Gaps = 57/522 (10%)
Query: 156 TKHWSSSSASPPPKKKKKKKG------GHRRSRKKRRLESECSCGSSSPLRKKKKS---- 205
++HW SS + + ++ GH ++ ++ E + S + S
Sbjct: 3330 SRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQ 3389
Query: 206 VKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSL 265
V H + S G R R + S E+ ++ R G+ + R GSS
Sbjct: 3390 VSTHEQSESAHGRTRTSTGRRQGS---HHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQ 3446
Query: 266 SSHYSDSRSPSRLSPKHR----DEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRS 321
SHY S S S H +GR S+ SGSRS S + +++G + S
Sbjct: 3447 GSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQ----TRNDEQSGDGSRHS 3502
Query: 322 GAHGGR-----PGSAHSPPDKPSSPSPRV-RDKAAAAAPTPPARGKESPSPR-SAPSSQG 374
+H S HS + S PR R++ ++ + ++G S R S +S+
Sbjct: 3503 WSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRN 3562
Query: 375 RGGRAAGGAGRRRRRRRRRRRSRS----SASAPRRRGRRRPRPAPPRGSSRSLSRARSSS 430
G A + R R+ SA + R+ G + ++ S +ARSS+
Sbjct: 3563 HRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSA 3622
Query: 431 DSGSG-RGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSS 489
G S GHG ++ R S + H + S+
Sbjct: 3623 GERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAH 3682
Query: 490 RSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATR 549
GPH +S S +R RSA + RS S +S + E A +T
Sbjct: 3683 GQAGPHQQSHQES-----TRGRSAGR----SGRSGSFLYQVSTHEQSES-AHGRAGPSTG 3732
Query: 550 ARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSR 609
R+ SR ++ RDS SA + R P S Y +S R
Sbjct: 3733 GRQGSR-----HEQARDSSRH-------SASQEGQDTIRGHPGSRRGGRQGSYHEQSVDR 3780
Query: 610 SPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESG 651
S G H +S+ S +S SR S S +R+ +SG
Sbjct: 3781 SGHSGSHHSHTTSQGRSDASHGQSGSR--SASRETRNEEQSG 3820
Score = 74.7 bits (182), Expect = 2e-13
Identities = 134/564 (23%), Positives = 186/564 (32%), Gaps = 96/564 (17%)
Query: 150 GHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKH 209
GH G H +S S + G R + ++ R E + G+ + S +H
Sbjct: 540 GHSGSHHSHTTSQGRSDA----SHGQSGSRSASRQTRNEEQSGDGT-------RHSGSRH 588
Query: 210 RRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKK-RPHTESPGRRSHRHS-SGSSHSPSLSS 267
S + S R + S R +N+ ++S G SGS+ S
Sbjct: 589 HEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGS 648
Query: 268 HYSDSRSPSRLSPKHRDE----GRKTGSQRSSGSRSP--SPSGGSGWGSPQRNGGSGQRS 321
SR SR H ++ G S R SG+R S SG + Q +G+R
Sbjct: 649 AQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERH 708
Query: 322 GAHG---GRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGR 378
G+ S HS + S VRD + A E S S S G+
Sbjct: 709 GSRHQLQSADSSRHSGTGHGQASSA-VRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQ 767
Query: 379 AAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGA 438
A G ++ + R RS R RR GS S+S G
Sbjct: 768 A----GHHQQSHQESARDRSG-----ERSRRS-------GSFLYQVSTHKQSESSHGWTG 811
Query: 439 PGPGPEPGSE--------------------RGHGGHGKRAKERPPRARPASTSPSPGAH- 477
P G GS RGH G +R ++ + S G+H
Sbjct: 812 PSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHH 871
Query: 478 ------GRRGGPEGKSSSRSPGPHPRSWSSSRSPSK-SRSRSAEKRPHSPSRSPSPK--- 527
GR G+S SRS R+ SR S+ S SR E H+ S
Sbjct: 872 SHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQG 931
Query: 528 ------------KPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRR--RDSPSFMEP 573
+S+D D EG + SE + A R R + + R R S E
Sbjct: 932 QSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHED 991
Query: 574 RR-----ITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTR 628
R S+R+ P+ SS SS RS SPG HGS +S +
Sbjct: 992 RAGHGHSADSSRQSGTPH--AETSSGGQAASSHEQARS-----SPGERHGSRHQQSADSS 1044
Query: 629 SRTRSPSRTPSPSYHSRSSSESGG 652
+ P R S + S G
Sbjct: 1045 RHSGIPRRQASSAVRDSGHWGSSG 1068
Score = 74.3 bits (181), Expect = 3e-13
Identities = 123/539 (22%), Positives = 191/539 (35%), Gaps = 86/539 (15%)
Query: 150 GHRGYRTKHWSSSSASPPPKKKKK-----KKGGHRRSRKK--RRLESECSCGSSSPLRK- 201
GHRGY S + + + G H++S ++ R E S S S L +
Sbjct: 3007 GHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQV 3066
Query: 202 --KKKSVKKHR----RDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRH 255
++S H R GSR ++ S + ++ + P + GR+ + H
Sbjct: 3067 STHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHH 3126
Query: 256 SSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNG 315
S SH+S + S +GR S+ SGSRS S + + +
Sbjct: 3127 EHSVDSSGHSGSHHSHTTS----------QGRSDASRGQSGSRSASRTTRN-----EEQS 3171
Query: 316 GSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGR 375
G R S H+ + S + + + + ++S S + S+
Sbjct: 3172 GDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERW 3231
Query: 376 GGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRP--APPRGSSRSLSRARSS---- 429
G A+ R R S R G R PR G S R+R S
Sbjct: 3232 SGSAS-------------RNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRH 3278
Query: 430 SDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRAR----PASTSPSPGAHGRRGGPEG 485
+++ SG A + S G HG R ++ +R P + S R G G
Sbjct: 3279 AETSSGGQAASSHEQARSSPGE-RHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSG 3337
Query: 486 KSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDG--EGR---- 539
+S S G S S ++S S + PH S S +RD+ G GR
Sbjct: 3338 SQASDSEG------HSEESDTQSVSGHGQAGPHQQSHQES-----ARDRSGGRSGRSGSF 3386
Query: 540 ----ARHSEAEATRARRRS---RSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPS 592
+ H ++E+ R R+ R ++ RDS SA + R P
Sbjct: 3387 LYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRH-------SASQEGQDTIRGHPG 3439
Query: 593 SSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESG 651
SS + +S RS G H +S+ SR +S SR S S +R+ +SG
Sbjct: 3440 SSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSR--SASRQTRNDEQSG 3496
Score = 73.9 bits (180), Expect = 4e-13
Identities = 110/472 (23%), Positives = 160/472 (33%), Gaps = 68/472 (14%)
Query: 203 KKSVKKHRRDRSDSGSRRKRRHRSR--SSKCKRKEKNKEKKRPHTESP--GRRSHRHSSG 258
++S H R R+ +G R+ H SS+ ++ ++ R H S GR+ H
Sbjct: 1125 EQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQS 1184
Query: 259 SSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQ------------RSSGSRSPSPSGGS 306
S SH+S + S R H G ++ S+ R SGSR +
Sbjct: 1185 VDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHE---AA 1241
Query: 307 GWGSPQRNG------GSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARG 360
W R+ SG R+ H G S S ++ S S R+ + +A+
Sbjct: 1242 SWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERL---SGSASRNHHGSS 1298
Query: 361 KESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAP-PRGS 419
+E S + RA+ G R+ + SS+ + R +P R
Sbjct: 1299 REQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHG 1358
Query: 420 SRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGR 479
SR A SS SG G RG G E S + S AHG
Sbjct: 1359 SRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSE---DSDTQSVSAHG- 1414
Query: 480 RGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGR 539
+ GP +S H S S RSRS + S +S S + G
Sbjct: 1415 QAGPHQQS-------HKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQG 1467
Query: 540 ARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLS 599
+RH + AR SR SA + R P SS
Sbjct: 1468 SRHEQ-----ARNSSRH---------------------SASQDGQDTIRGHPGSSRGGRQ 1501
Query: 600 SDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESG 651
Y +S RS G+ H + + S +S R S S +R+ +SG
Sbjct: 1502 GSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPR--SASRQTRNEEQSG 1551
Score = 72.0 bits (175), Expect = 2e-12
Identities = 142/596 (23%), Positives = 205/596 (34%), Gaps = 101/596 (16%)
Query: 133 DDDDGPVDCDCPASCYRGHRGYRTK-HWSSSSASPPPKKKKKKKGGHRRSRKKRRLESEC 191
D + D D + G G+ + H S+ + ++ ++ S K+ S
Sbjct: 749 DSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHG 808
Query: 192 SCGSSSPLRK---KKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESP 248
G S+ +R+ +++ R S G R H S + ++ +++ S
Sbjct: 809 WTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSG 868
Query: 249 GRRSHRHSSGSSHSPSLSSHYSDSRSPSRLS---PKHRDEGRKTGSQ------------- 292
SH S G S + S S SRS SR + + RD R +GS+
Sbjct: 869 SHHSHTTSQGRSDA---SRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRH 925
Query: 293 ------RSSGSRSPSPSGGS---------------GW-GSPQRN-GGSGQRSGAHGGRPG 329
+S GSR+ G S W GS RN GS Q HG R
Sbjct: 926 SQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHP 985
Query: 330 SAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRR 389
+H D+A +R +S +P + SS GG+AA + R
Sbjct: 986 RSHH------------EDRAGHGHSADSSR--QSGTPHAETSS---GGQAASSHEQARSS 1028
Query: 390 RRRRRRSRSSASA--------PRRRGRRRPRPAPPRGSSRSLS------RARSSSDSGSG 435
R SR SA PRR+ R + GSS S + S + S SG
Sbjct: 1029 PGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSG 1088
Query: 436 RGAPGPGPEPGSERGHGGHGKRAKERPPRARPAST-SPSPGAHGRRGGPEGKSSSRSPGP 494
G GP + E G R+ ST S AHGR S+ R G
Sbjct: 1089 HGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGR----TRTSTGRRQGS 1144
Query: 495 HPRSWSSSRSPSKSRSRSAEKRPHSPSR---SPSPKKPLSRDKDGEGRARH----SEAEA 547
H S S S+ R H SR S D+ G + H S+ +
Sbjct: 1145 HHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRS 1204
Query: 548 TRARRRSRSYSPIRKRRRDSPSFMEPRR-----------ITSARKRPIPYYRPSPSSSSS 596
+ +S S S R+ R+D S R S+R + + S S +S
Sbjct: 1205 DASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSR 1264
Query: 597 CLSSDYSTRSHSRSPSPGHSHGSYS-SRSHGTRSRTRSPSRTPSPSYHSRSSSESG 651
S S S S S S S SR+H SR +S + P +H + G
Sbjct: 1265 HQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHG 1320
Score = 72.0 bits (175), Expect = 2e-12
Identities = 123/530 (23%), Positives = 172/530 (32%), Gaps = 62/530 (11%)
Query: 146 SCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKS 205
S R H G + S S P ++ + H S R SSS ++
Sbjct: 1289 SASRNHHG--SSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSS----HGQA 1342
Query: 206 VKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSL 265
V H + RS G R RH+ + + + G HR SSGS + S
Sbjct: 1343 VSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSG---HRGSSGSQVTNS- 1398
Query: 266 SSHYSDSRSPS-----RLSP---KHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGS 317
H DS + S + P H++ R + S SRS S Q
Sbjct: 1399 EGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSS---HEQSESTH 1455
Query: 318 GQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARG------KESPSPRSAPS 371
GQ + + GGR GS H S S + +RG E RS S
Sbjct: 1456 GQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHS 1515
Query: 372 S--------QGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSR-- 421
QGR + G +G R R+ R + S R G R P+ GSSR
Sbjct: 1516 GYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQ-SGDGSRHSGSRHHEPSTRAGSSRHS 1574
Query: 422 SLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRG 481
+ + S+ S R + SE GH +R E R S R G
Sbjct: 1575 QVGQGESAGSKTSRRQGSSVSQDRDSE-GHSEDSERRSESASRNHYGSAR----EQSRHG 1629
Query: 482 GPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRAR 541
+S H S SSR + ++ + S+ + P R ++
Sbjct: 1630 SRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSA 1689
Query: 542 HSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSD 601
S ++ RR+ S R S S + S S S S
Sbjct: 1690 DSSTDSGTGRRQDSSVVGDSGNRGSSGS------------------QASDSEGHSEESDT 1731
Query: 602 YSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESG 651
S +H ++ SH + G RS RS S S H +S S G
Sbjct: 1732 QSVSAHGQAGPHQQSHQESTRGQSGERS-GRSGSFLYQVSTHEQSESAHG 1780
Score = 69.7 bits (169), Expect = 8e-12
Identities = 122/530 (23%), Positives = 186/530 (35%), Gaps = 61/530 (11%)
Query: 146 SCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGH--RRSRKKRRLESECSCGSSSPLRKKK 203
S R H G + S +P ++ + GH SR+ +E S G
Sbjct: 1613 SASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGG-------- 1664
Query: 204 KSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSP 263
++ + RS G R RH+ + + +R + G +R SSGS S
Sbjct: 1665 QAASSQEQARSSPGERHGSRHQQSADS---STDSGTGRRQDSSVVGDSGNRGSSGSQASD 1721
Query: 264 SLS-SHYSDSRSPSRLSPKHRDEG-RKTGSQRSSGSRSPSPSGGSG------WGSPQRNG 315
S S SD++S S H G + Q S+ +S SG SG Q
Sbjct: 1722 SEGHSEESDTQSVS----AHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSES 1777
Query: 316 GSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGR 375
G+ + GGR S H + RD + + S S + +G
Sbjct: 1778 AHGRTGPSTGGRQRSRHE----------QARDSS-----------RHSASQEGQDTIRGH 1816
Query: 376 GGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSR-ARSSSDSGS 434
G + GG + S + + R + + SRS+SR R+ SG
Sbjct: 1817 PGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGD 1876
Query: 435 GRGAPGPGPEPGSERGHG------GHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSS 488
G G S R G G+ + R R + +S S + G E S
Sbjct: 1877 GSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSG 1936
Query: 489 SRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKD----GEGRARHSE 544
S S +W SR S+ E R + S ++ +R + G+ + H +
Sbjct: 1937 SASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQ 1996
Query: 545 AEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSA-RKRPIPYYRPSPSSSSSCLSSDYS 603
A ++ A R S+ ++ S + + +SA R Y S +S S S D
Sbjct: 1997 ARSS-AGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSD 2055
Query: 604 TRSHSRSPSPGHSHGSY--SSRSHGTRSRTRSPSRTPSPSYHSRSSSESG 651
T+S S G S+ S+R S RS S S H +S S G
Sbjct: 2056 TQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHG 2105
Score = 69.3 bits (168), Expect = 1e-11
Identities = 121/550 (22%), Positives = 177/550 (32%), Gaps = 93/550 (16%)
Query: 146 SCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGH----RRSRKKRRLESECSCGSSSPLRK 201
S R HRG + S S P+ + + GH RSR+ +E S G
Sbjct: 3234 SASRNHRG--SVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGG------ 3285
Query: 202 KKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSH 261
++ H + RS G R RH+ + + + + S R RH S
Sbjct: 3286 --QAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQ-----ASSAVRDSRHWGSSGS 3338
Query: 262 SPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSG---------WGSPQ 312
S S +S+ +S + + Q S+ RS SG SG S
Sbjct: 3339 QASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSES 3398
Query: 313 RNG----GSGQRSGAH--GGRPGSAHSPPDKPSS-----PSPRVRDKAAAAAPTPPARGK 361
+G +G+R G+H R S HS + P R + + R
Sbjct: 3399 AHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSG 3458
Query: 362 ESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSR 421
S S S +SQGR + G +G R R+ R +S G R S++
Sbjct: 3459 HSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSG------DGSRHSWSHHHEASTQ 3512
Query: 422 SLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRG 481
+ S S S G G P + R G + + + + + RG
Sbjct: 3513 ADSSRHSQSGQGQSAG-------PRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRG 3565
Query: 482 GPEGKSSSRSPGPHPRSWSSSR-----SPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDG 536
+ SR HP S R S SR +S + +R G
Sbjct: 3566 --SAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAG 3623
Query: 537 EGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSS 596
E H + A +R + RDS R +S S +S S
Sbjct: 3624 ERHGSHHQQSADSSRHSGIGHGQASSAVRDS-----GHRGSSG----------SQASDSE 3668
Query: 597 CLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRT--------------PSPSY 642
S D T+S S H +SH +R RS R+ S S
Sbjct: 3669 GHSEDSDTQSVS-----AHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESA 3723
Query: 643 HSRSSSESGG 652
H R+ +GG
Sbjct: 3724 HGRAGPSTGG 3733
Score = 68.6 bits (166), Expect = 2e-11
Identities = 116/524 (22%), Positives = 181/524 (34%), Gaps = 70/524 (13%)
Query: 150 GHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRL-ESECSCGSSSPLRKKKKSVKK 208
GH G H +S S + + + R +R + + + GS + +
Sbjct: 2810 GHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISR 2869
Query: 209 HRR--DRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSS-----GSSH 261
H + GSRR RR S S+ E + E + S R H + GS H
Sbjct: 2870 HSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRH 2929
Query: 262 SPSLSSHYSDSRSPSRLSPKHRDEGRK-----TGSQRSSGSRSPSPSGGSGWGSP-QRNG 315
SH D + R G + +G Q +S S G GS Q++
Sbjct: 2930 P---RSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSA 2986
Query: 316 GSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPP----ARGKESPSPRS-AP 370
S + SG G+ SA + D + + A G+ +S
Sbjct: 2987 DSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQE 3046
Query: 371 SSQGRGGRAAGGAGRRRRRRRRRRRSRSSA--SAPRRRGRRRPRPAPPRGSSRSLSRARS 428
S++GR G +G +G + +S SS + P RGR+ R + SSR S
Sbjct: 3047 SARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSR-----HS 3101
Query: 429 SSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSS 488
+S G + RGH G + ++ +S G+H +G+S
Sbjct: 3102 ASQYGQD-----------TIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSD 3150
Query: 489 SRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEAT 548
+ R S SRS S++ +R+ E+ S S S S D ++ + ++
Sbjct: 3151 AS------RGQSGSRSASRT-TRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSE 3203
Query: 549 RARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHS 608
+RR R S + + DS S S S S ++R+H
Sbjct: 3204 GSRRSRRQGSSVSQ---DSDS--------------------EGHSEDSERWSGSASRNHR 3240
Query: 609 RSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESGG 652
S HGS RSH S S +R + S G
Sbjct: 3241 GSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSG 3284
Score = 67.0 bits (162), Expect = 5e-11
Identities = 120/534 (22%), Positives = 188/534 (35%), Gaps = 73/534 (13%)
Query: 150 GHRGYRTKHWSSSSASPPPKKKKK-----KKGGHRRSRKK--RRLESECSCGSSSPLRK- 201
GHRGY S + + + G H++S ++ R E S S S L +
Sbjct: 2683 GHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQV 2742
Query: 202 --KKKSVKKHR----RDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRH 255
++S H R GSR ++ S + ++ + P + GR+ + H
Sbjct: 2743 STHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHH 2802
Query: 256 SSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNG 315
S SH+S + S +GR S+ SGSRS S + + +
Sbjct: 2803 EHSVDSSGHSGSHHSHTTS----------QGRSDASRGQSGSRSASRTTRN-----EEQS 2847
Query: 316 GSGQRSGAHGGRPGSAHSPPDK-------PSSPSPRVRDKAAAAAPTPPARGKESPSPR- 367
G G R S H+ + S S R R + ++ + + G S R
Sbjct: 2848 GDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERW 2907
Query: 368 SAPSSQGRGGRA----AGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSL 423
S +S+ G A G+ R + R SA + R+ G R + + ++ S
Sbjct: 2908 SGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSH 2967
Query: 424 SRARSSSDSGSG-RGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGG 482
+ARSS+ G S GHG ++ R S + H
Sbjct: 2968 EQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSD 3027
Query: 483 PEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPS---------RSPSPKKPLSRD 533
+ S+ G H +S S +R RS E HS S +S S
Sbjct: 3028 TQSVSAHGQAGSHQQSHQES-----ARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPS 3082
Query: 534 KDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSS 593
G +RH +A+ + +R + Y + R P S+R Y+
Sbjct: 3083 TRGRQGSRHEQAQDS-SRHSASQYG--QDTIRGHPG--------SSRGGRQGYHH----- 3126
Query: 594 SSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSR-TRSPSRTPSPSYHSRS 646
S SS +S HS + S G S S + SR TR+ ++ S HS S
Sbjct: 3127 EHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVS 3180
Score = 66.6 bits (161), Expect = 7e-11
Identities = 113/523 (21%), Positives = 186/523 (35%), Gaps = 52/523 (9%)
Query: 150 GHRGYRTKHWSSSSASPPPKKKKK-----KKGGHRRSRKKR-RLESECSCGSSSP----L 199
GHRG S S + + G H++S ++ R S G S +
Sbjct: 2359 GHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQV 2418
Query: 200 RKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKK----RPHTESPGRRSHRH 255
++S H R + +G R+ H+ + + + P + S GR+ +
Sbjct: 2419 STHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHY 2478
Query: 256 SSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNG 315
S SH+S + S R H G ++ S++ +R+ SG S R+
Sbjct: 2479 EQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQ---TRNDEQSGDGSRHSGSRHH 2535
Query: 316 GSGQRSGAHGGRPGSAHSPPDKPSSPSPRV-RDKAAAAAPTPPARGKESPSPR-SAPSSQ 373
+ R+ + G HS + S PR R+ ++ + ++G S R S +S+
Sbjct: 2536 EASSRADSSG------HSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASR 2589
Query: 374 GRGGRA----AGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSS 429
G A G+ R + R SA + R+ G R + + ++ S +ARSS
Sbjct: 2590 NHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSS 2649
Query: 430 SDSGSG-RGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSS 488
+ G S GHG ++ R S + H + S+
Sbjct: 2650 AGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSA 2709
Query: 489 SRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEAT 548
G H +S S +R RS E HS S +S + E + +T
Sbjct: 2710 HGQAGSHQQSHQES-----ARGRSGETSGHSGSF----LYQVSTHEQSES-SHGWTGPST 2759
Query: 549 RARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHS 608
R R+ SR ++ +DS SA + R P SS + S
Sbjct: 2760 RGRQGSR-----HEQAQDSSRH-------SASQDGQDTIRGHPGSSRGGRQGYHHEHSVD 2807
Query: 609 RSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESG 651
S G H +S+ SR +S SR+ S + + S G
Sbjct: 2808 SSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDG 2850
Score = 57.4 bits (137), Expect = 4e-08
Identities = 122/556 (21%), Positives = 181/556 (32%), Gaps = 81/556 (14%)
Query: 156 TKHWSSSSASPPPKKKKK-KKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRS 214
T+H SSS ++ + R +L+S S S + S + R
Sbjct: 1979 TRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRG 2038
Query: 215 DSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSG-------------SSH 261
SGS+ + + K PH +S + S R SG S+H
Sbjct: 2039 YSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSH-KESARGQSGESSGRSGSFLYQVSTH 2097
Query: 262 SPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRS 321
S S+H + S H D+ + + +S + G G R G ++S
Sbjct: 2098 EQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQS 2157
Query: 322 GAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAG 381
G GS H S + + R A+ G S S ++ Q G
Sbjct: 2158 VDRSGHSGSHH------SHTTSQGRSDASRG-----QSGSRSASRKTYDKEQSGDGSRHS 2206
Query: 382 GAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSL----------SRARSSSD 431
G+ S + G PR + PRGSS S S RS S
Sbjct: 2207 GSHHHEASSWADSSRHSLVGQGQSSG---PRTSRPRGSSVSQDSDSEGHSEDSERRSGSA 2263
Query: 432 SGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSS-- 489
S + G+ GS H ++R A +S G H G+++S
Sbjct: 2264 SRNHHGSAQEQSRDGSRHPRSHH----EDRAGHGHSAESSRQSGTHHAENSSGGQAASSH 2319
Query: 490 ---------RSPGPHPRSWSSSR------SPSKSRSRSAEKRPHSPSRSPSPKKPLSRDK 534
R H +S SSR + S R + R S S++ S + S D
Sbjct: 2320 EQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQA-SDSEGHSEDS 2378
Query: 535 DGEGRARHSEA--------EATRARRRSRSYSP----IRKRRRDSPSFMEPRRITSARKR 582
D + + H +A E+TR R RS + + R TS R
Sbjct: 2379 DTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGR 2438
Query: 583 PIPYYRPSPSSSSSCLSSDYSTRSHSR-SPSPGHSHGSY-------SSRSHGTRSRTRSP 634
+++ + SS S + H S G GS+ S S S T S
Sbjct: 2439 QGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQ 2498
Query: 635 SRTPSPSYHSRSSSES 650
R+ + HS S S S
Sbjct: 2499 GRSDASHGHSGSRSAS 2514
Score = 45.8 bits (107), Expect = 1e-04
Identities = 77/330 (23%), Positives = 115/330 (34%), Gaps = 37/330 (11%)
Query: 150 GHRGYRTKHWSSSSASPPPKKKKK-----KKGGHRRSRKKR-RLESECSCGSSSP----L 199
GHRG S S + + G H++S ++ R S G S +
Sbjct: 3655 GHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQV 3714
Query: 200 RKKKKSVKKHRRDRSDSGSRRKRRHRSR--SSKCKRKEKNKEKKRPHTES--PGRRSHRH 255
++S H R +G R+ RH SS+ ++ ++ R H S GR+ H
Sbjct: 3715 STHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYH 3774
Query: 256 SSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSG-GSGWGSPQRN 314
S SH+S + S R H G ++ S+ +R+ SG GS + +
Sbjct: 3775 EQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRE---TRNEEQSGDGSRHSGSRHH 3831
Query: 315 GGSGQRSGAHGGRPGSAHSPPDKPS--SPSPRVRDKAAAAAPTPPARGKESPSPRSAPSS 372
S Q + + G S + S S +D + A P R ES S SS
Sbjct: 3832 EASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSS 3891
Query: 373 --QGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSS 430
Q R G G+ R + S S+ A G SLS+ +
Sbjct: 3892 REQSRDGSRHPGSSHRDTASHVQSSPVQSDSS----------TAKEHGHFSSLSQDSAYH 3941
Query: 431 DSGSGRGAPGPG-----PEPGSERGHGGHG 455
RG+P G+ER G G
Sbjct: 3942 SGIQSRGSPHSSSSYHYQSEGTERQKGQSG 3971
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 86.7 bits (213), Expect = 6e-17
Identities = 125/462 (27%), Positives = 183/462 (39%), Gaps = 56/462 (12%)
Query: 199 LRKKKKSVK--KHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHS 256
LRK K+ + KH + + K + R S+ +R+E +++ R SP
Sbjct: 239 LRKDKEEAEAIKHAKALEEE----KAMYSGRRSRRQRREFREKRLRGRKISP-------- 286
Query: 257 SGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGG-------SGWG 309
PS + S + P + SP ++ S+ S SRSP+P S G
Sbjct: 287 ------PSYARRDSPTYDPYKRSPS------ESSSESRSRSRSPTPGREEKITFITSFGG 334
Query: 310 SPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSA 369
S + + + A G G +PP +P P+P R+ +A + + + S+
Sbjct: 335 SDEEAAAAAAAAAASGVTTGKPPAPP-QPGGPAPG-RNASARRRSSSSSSSSSASRTSSS 392
Query: 370 PSSQGRGGRAAGGAGRRRRRRRRRRRSRS-SASAPRRRGRRRPRPAPPRGSSRSLSRARS 428
SS R+ G G R R R RSRS S S R R R R R S
Sbjct: 393 RSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHR 452
Query: 429 SSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHG-RRGGPEGKS 487
S S + RG GP S R H G R R R +S S S + R +S
Sbjct: 453 YSRSPARRGGYGPRRRSRS-RSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRS 511
Query: 488 SSRSPGP---HPRSWSSSRSPSKSRSRSAEKRPH-SPSRSPSPKK--PLSRDKDGEGRAR 541
S SP P RS S S+SPS S +R RP SP+ KK P + + G + +
Sbjct: 512 RSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPK 571
Query: 542 HSEAEATRARRR---SRSYSPIRKRRRDSPSFMEPRR------ITSARKRPIPYYRPSPS 592
+ E + R + +R + +K ++ E R + + ++ R
Sbjct: 572 LTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERRE 631
Query: 593 SSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSP 634
YS +S RSPSP +S YSS +RSR+RSP
Sbjct: 632 KEREEWERQYSRQS--RSPSPRYSR-EYSSSRRRSRSRSRSP 670
Score = 85.5 bits (210), Expect = 1e-16
Identities = 101/296 (34%), Positives = 122/296 (41%), Gaps = 60/296 (20%)
Query: 383 AGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSR-ARSSSDSGSGRGAPGP 441
+GRR RR+RR R + R RGR+ P+ R S + RS S+S S +
Sbjct: 263 SGRRSRRQRREFREK------RLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSR 316
Query: 442 GPEPGSER------GHGGHGKRAKERPPRAR---------PASTSPSPGAHGRRGGPEGK 486
P PG E GG + A A PA P A GR +
Sbjct: 317 SPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRR 376
Query: 487 SSSRSPGPHPRSWSSSRSPSKSRSRS------------AEKRPHSPSRSPSPKKPLSRDK 534
SSS S SSSRS S+S SRS A R S SRS S + SR +
Sbjct: 377 SSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSR 436
Query: 535 DGEGRARHSEAEATRARRRSRS------YSPIRKRRRDSPSFMEPRRITSARKRPIPYYR 588
GR RHS + R SRS Y P R+ R S S RR R + ++
Sbjct: 437 S-RGR-RHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRR----GGRGLRHHS 490
Query: 589 PSPSSSSSCLSSDYS---TRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPS 641
S S SS LS S TRS S SPSP S RSR+RS S++PSPS
Sbjct: 491 SSRSRSSWSLSPSRSRSLTRSRSHSPSPSQS-----------RSRSRSRSQSPSPS 535
Score = 72.0 bits (175), Expect = 2e-12
Identities = 89/367 (24%), Positives = 136/367 (37%), Gaps = 57/367 (15%)
Query: 162 SSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRK 221
++ PP + R + +RR S S S+S + S + R R G R
Sbjct: 352 TTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRS 411
Query: 222 RRH-RSRS-------SKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSD-- 271
RH RSRS S+ +R +++ + R H+ R HR+ S SP+ Y
Sbjct: 412 GRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRY----SRSPARRGGYGPRR 467
Query: 272 -SRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGS 330
SRS S ++R GR G + S SRS S W S RS +H
Sbjct: 468 RSRSRSHSGDRYRRGGR--GLRHHSSSRS-----RSSWSLSPSRSRSLTRSRSH------ 514
Query: 331 AHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRR 390
PS R R ++ + +P+P ++ P ++P A G
Sbjct: 515 ------SPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASP--------AVG--------- 551
Query: 391 RRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERG 450
+ ++ +A + G +P+ P + +A + + A + ER
Sbjct: 552 --EKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQ 609
Query: 451 HGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGP-HPRSWSSSRSPSKSR 509
RA R R + R + SRSP P + R +SSSR S+SR
Sbjct: 610 EREDELRAMARKIRMKERERREKEREEWER---QYSRQSRSPSPRYSREYSSSRRRSRSR 666
Query: 510 SRSAEKR 516
SRS R
Sbjct: 667 SRSPHYR 673
Score = 71.6 bits (174), Expect = 2e-12
Identities = 112/460 (24%), Positives = 167/460 (36%), Gaps = 52/460 (11%)
Query: 169 KKKKKKKGGHRRSRKKRRLESECSCGS--SSPLRKKKKSVKKHRRDRSDSGSRRKRRHRS 226
+++K G R R++R + G S P ++ S RS S S + R RS
Sbjct: 256 EEEKAMYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRS 315
Query: 227 RSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEG 286
RS R+EK T + ++ + + +S + + P+ P G
Sbjct: 316 RSPTPGREEKI-------TFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPG 368
Query: 287 RKTGSQR--------SSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKP 338
R ++R SS SR+ S S S R GG RSG H + S
Sbjct: 369 RNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSR 428
Query: 339 SSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRS 398
S R R + + G R + S RGG RRR R RS
Sbjct: 429 SRRYSRSRSRGRRHSG-----GGSRDGHRYSRSPARRGGYGP--------RRRSRSRSH- 474
Query: 399 SASAPRRRGRRRPRPAPPRG-SSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKR 457
S RR GR + R SS SLS +RS S + S +P P R
Sbjct: 475 SGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSP 534
Query: 458 AKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRP 517
+ R RPA+ SP+ G ++ P + + P + + K R + A R
Sbjct: 535 SPAREKLTRPAA-SPAVGEKLKKTEPAAGKETGAAKPK----LTPQEKLKLRMQKALNRQ 589
Query: 518 HSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRIT 577
+ + +K + ++ + + R A A + R + R RR+ R+ +
Sbjct: 590 FKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKER-------ERREKEREEWERQYS 642
Query: 578 SARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSH 617
+ P P Y SSS RS SRS SP + H
Sbjct: 643 RQSRSPSPRYSREYSSS--------RRRSRSRSRSPHYRH 674
Score = 57.8 bits (138), Expect = 3e-08
Identities = 60/180 (33%), Positives = 72/180 (40%), Gaps = 20/180 (11%)
Query: 478 GRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGE 537
GR+ P + SP P S S S S+SRSRS RSP+P +
Sbjct: 281 GRKISPPSYARRDSPTYDPYKRSPSESSSESRSRS---------RSPTPGREEKITFITS 331
Query: 538 GRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSC 597
EA A A + + + P P R SAR+R S SSSSS
Sbjct: 332 FGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRS------SSSSSSSS 385
Query: 598 LSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPS-----YHSRSSSESGG 652
S S+RS SRS S G Y RSR+RS SR+ S S SR SGG
Sbjct: 386 ASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGG 445
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 83.6 bits (205), Expect = 5e-16
Identities = 118/544 (21%), Positives = 205/544 (37%), Gaps = 77/544 (14%)
Query: 151 HRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHR 210
+ YR + + +++++++ R R++R E E R+ ++ ++ R
Sbjct: 398 YHNYRERERERERENRQRERERERERDRERERRQRERERE---------REHERDKERQR 448
Query: 211 RDRSDSGSRRKRRHRSRSSKCKRKEKNKEKK----RPHTESPGRRS----HRHSSGSSHS 262
R R KR + R + + +EK +EK+ +P + P R + ++ +
Sbjct: 449 RKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQ 508
Query: 263 PSLSSHYSD----SRSPSR-----LSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQR 313
+ + D S+SP + +SP RKT S+ S S S S S S
Sbjct: 509 VKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRKT----SASSASASNSSRSSSRSSSY 564
Query: 314 NGGSGQRSGAHGGRPGSAHSPPDKPSSPS-PRVRDKAAAAAPTPPARGKESPSP-RSAPS 371
+G RS + S S + SS S R R ++ +++P+P +PSP R +
Sbjct: 565 SGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSP----SPTPSPHRPSIR 620
Query: 372 SQGRGGRAAGGAGRRRRRR-----RRRRRSRSSASAPR-------RRGRRRPRPAPPRGS 419
++G G AG + ++ + ++++A P R RR+ RPA
Sbjct: 621 TKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPA----- 675
Query: 420 SRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGR 479
R+ R R+ S SGSG G+ G S + A + S +
Sbjct: 676 -RTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYAD 734
Query: 480 RGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGR 539
P +SSRSP P +S + + +++ S ++ P KP + K +
Sbjct: 735 LASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQP 794
Query: 540 ARHSEA------EATRARRRSRSYSPIRK------RRRDSPSFMEPRRITSARKRPIPYY 587
+ +A + T + + + K R+R PS + R+ P P
Sbjct: 795 STPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKD-------RQSPPPAK 847
Query: 588 RPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSS 647
RP+ S S D + SP P G S R R S P S+ +
Sbjct: 848 RPNTSPDRG--SRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLS--PQSKSSSKVT 903
Query: 648 SESG 651
S G
Sbjct: 904 SVPG 907
Score = 79.7 bits (195), Expect = 8e-15
Identities = 123/485 (25%), Positives = 177/485 (36%), Gaps = 89/485 (18%)
Query: 162 SSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRK 221
S + PPKK+ G + KR E + P R+ K KK S S +RR+
Sbjct: 492 SRQAEPPKKEAATTG----PQVKRADEWK------DPWRRSKSPKKKLGVSVSPSRARRR 541
Query: 222 RRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPK 281
R+ + S+ + S R S SGSS S S SS YS S S S +
Sbjct: 542 RKTSASSASASNSSR----------SSSRSSSYSGSGSSRSRSRSSSYS---SYSSRSSR 588
Query: 282 HRD-EGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSS 340
H G ++ S+ S S SPSP+ S + G G G + +PP
Sbjct: 589 HSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPP----- 643
Query: 341 PSPRVRDKAAAAAPTP-------PARGKESPS---PRSAPSSQGRGGRAAGGAGRRRRRR 390
P+P K A P P AR KE P+ PR S G + +G R R
Sbjct: 644 PAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSR 703
Query: 391 RRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAP-----GPGPEP 445
S SS S+ SS S + + S D + +P P P
Sbjct: 704 SLSVSSVSSVSSAT--------------SSSSSAHSVDSEDMYADLASPVSSASSRSPAP 749
Query: 446 GSERGHGGHGKR--AKERPPRARPASTSPSPGAHGRRGGPEGKSSS---RSPGPHPRSWS 500
R G K+ + R R +ST P A GG + S ++P P+ +
Sbjct: 750 AQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGT 809
Query: 501 --------------SSRSPSKSRSRSAEKRPHSPSRSPSPKKPL------SRDKDGEGRA 540
++ S+ R ++K SP P K+P SRD+ GR
Sbjct: 810 FVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSP---PPAKRPNTSPDRGSRDRKSGGRL 866
Query: 541 RHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSS 600
+ E R + +P ++R+ SP ++TS P P +S+ S +S
Sbjct: 867 GSPKPERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSV---PGKASDPGAASTKSGKAS 923
Query: 601 DYSTR 605
S R
Sbjct: 924 TLSRR 928
Score = 74.7 bits (182), Expect = 2e-13
Identities = 112/496 (22%), Positives = 177/496 (35%), Gaps = 104/496 (20%)
Query: 175 KGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRK 234
+GG + + + E+E R++++ ++ R+R R + R + + +
Sbjct: 381 RGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERERRQREREREREH 440
Query: 235 EKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRS 294
E++KE++R E R+ R +HRD R+ ++
Sbjct: 441 ERDKERQRRKEEWERERAKRDEK---------------------DRQHRDRDREKEREKE 479
Query: 295 SGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAP 354
G P SPQ P S + P K + + + K A
Sbjct: 480 KGKPKPR--------SPQ---------------PPSRQAEPPKKEAATTGPQVKRADEWK 516
Query: 355 TPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPA 414
P R K SP+ + G + R RRRR+ S SSASA R R +
Sbjct: 517 DPWRRSK---SPK----------KKLGVSVSPSRARRRRKTSASSASA-SNSSRSSSRSS 562
Query: 415 PPRGSSRSLSRARSSS-DSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPS 473
GS S SR+RSSS S S R S R G R++ R + P S SP+
Sbjct: 563 SYSGSGSSRSRSRSSSYSSYSSR----------SSRHSSFSGSRSRSRSFSSSP-SPSPT 611
Query: 474 PGAH-------GRRGGPEGKSSSRS-----PGPHPRSWSSSRSPSKSRSRSAEKRPHSPS 521
P H G P GK+ +S P P P + + +P ++ + R
Sbjct: 612 PSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRK 671
Query: 522 RSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARK 581
P+ P R G G S + +R RS S S + ++SA
Sbjct: 672 ERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSS-------------VSSATS 718
Query: 582 RPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHS--HGSYSSRSHGTRSRTR------S 633
+ + L+S S+ S SRSP+P + S + G + R
Sbjct: 719 SSSSAHSVDSEDMYADLASPVSSAS-SRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQ 777
Query: 634 PSRTPSPSYHSRSSSE 649
P ++ P +SS +
Sbjct: 778 PPKSAKPPAGGKSSQQ 793
Score = 53.5 bits (127), Expect = 6e-07
Identities = 93/392 (23%), Positives = 135/392 (34%), Gaps = 38/392 (9%)
Query: 145 ASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKK-- 202
+S Y G R++ SSS +S + + RSR + S + SP R
Sbjct: 561 SSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIR 620
Query: 203 -------------KKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPG 249
+KSVKK + + + +K + + K+RP +P
Sbjct: 621 TKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERP-ARTPP 679
Query: 250 RRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWG 309
RR SGS S S S SRS LS S SS S +
Sbjct: 680 RRRTLSGSGSGSGSSYSGSSSRSRS---LSVSSVSSVSSATSSSSSAHSVDSEDMYADLA 736
Query: 310 SPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAA--AAAPTPPARGKES---P 364
SP + S + A R S + R RD + + PPA GK S
Sbjct: 737 SPVSSASSRSPAPAQ-TRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPS 795
Query: 365 SPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLS 424
+P+ AP Q + G + + ++ S R + R +PP + S
Sbjct: 796 TPQQAPPGQPQQGTF---VAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTS 852
Query: 425 RARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPE 484
R S D SG G G P+P +RG A P R SP + +
Sbjct: 853 PDRGSRDRKSG-GRLG-SPKPERQRGQNSKAPAA----PADRKRQLSPQSKSSSKVTSVP 906
Query: 485 GKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKR 516
GK+S P S S ++ + SR K+
Sbjct: 907 GKASD----PGAASTKSGKASTLSRREELLKQ 934
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 82.4 bits (202), Expect = 1e-15
Identities = 88/276 (31%), Positives = 116/276 (42%), Gaps = 37/276 (13%)
Query: 173 KKKGGHRRSRKKRRL---ESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSS 229
K K H +S+K + E E SS R K+ +H+ + S SR + R RS S
Sbjct: 1795 KVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKS 1854
Query: 230 KCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKT 289
K R + T S R R S S S S S S+ + SPKHR + R+
Sbjct: 1855 KSHRSQ---------TRSRSRSRRRRRSSRSRSKS-RGRRSVSKEKRKRSPKHRSKSRER 1904
Query: 290 GSQRSSG--------SRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSP 341
+RSS +RS +PS S +P R +RS + G R + SP + +P
Sbjct: 1905 KRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRR----RRSRSVGRRRSFSISPSRRSRTP 1960
Query: 342 SPRVRDKAAAAAPTPPARGKESPSPRS-APSSQGRGGRAAGGAGRRRRRRRRRRRSRSSA 400
S R R P+R +PS RS PS + R RRRR R R RS +
Sbjct: 1961 SRRSR---------TPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFS 2011
Query: 401 SAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGR 436
+P R RR R R SRS R + S S GR
Sbjct: 2012 ISPVR--LRRSRTPLRRRFSRSPIRRKRSRSSERGR 2045
Score = 70.5 bits (171), Expect = 5e-12
Identities = 82/261 (31%), Positives = 108/261 (41%), Gaps = 35/261 (13%)
Query: 336 DKPSSPSPRVRDKAAAAAPTPPA-RGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRR 394
+K S R R K + ++ R ES S SS+ + R+ + R RRRRR
Sbjct: 1815 EKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSS 1874
Query: 395 RSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGH 454
RSRS S RR + R P+ S+S R R S S R
Sbjct: 1875 RSRSK-SRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTV--------------- 1918
Query: 455 GKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSS-SRSPSKSRSRSA 513
RA+ R P R S +PS R G +S S SP R+ S SR+PS+ RSR+
Sbjct: 1919 --RARSRTPSRRSRSHTPSRRRRSRSVGRR-RSFSISPSRRSRTPSRRSRTPSR-RSRTP 1974
Query: 514 EKRPHSPSRSPSPKKPLSRDKDGEGRARH---------SEAEATRAR---RRSRSYSPIR 561
+R +PSR SR R+R S R+R RR S SPIR
Sbjct: 1975 SRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIR 2034
Query: 562 KRR-RDSPSFMEPRRITSARK 581
++R R S P+R+T K
Sbjct: 2035 RKRSRSSERGRSPKRLTDLDK 2055
Score = 68.2 bits (165), Expect = 2e-11
Identities = 82/296 (27%), Positives = 113/296 (38%), Gaps = 33/296 (11%)
Query: 313 RNGGSGQRSGAHGGRPGSAHSP-----PDKPSSPSPRVRDKAAAAAPTPPARGKESPSPR 367
R G G + GR SA SP P++ S S +D K S +
Sbjct: 1749 RAGIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEK---SKK 1805
Query: 368 SAPSSQGRGGRAAGGAGRRRRRRR-------RRRRSRSSASAPRRRGRRRPRPAPPRGSS 420
+ +G + + R R +R R+R S S + A +R + + + R S
Sbjct: 1806 NKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRS 1865
Query: 421 RSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRR 480
RS R RSS RG E + H +++ER R R +S R
Sbjct: 1866 RSRRRRRSSRSRSKSRGRRSVSKE--KRKRSPKHRSKSRER-KRKRSSSRDNRKTVRARS 1922
Query: 481 GGPEGKSSSRSPGPHPRSWSSSR------SPSKSRSRSAEKRPHSPSRSPSPKKPLSRDK 534
P +S S +P RS S R SPS+ RSR+ +R +PSR SR
Sbjct: 1923 RTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSR-RSRTPSRRSRTPSRRSRTPSRRSRTP 1981
Query: 535 DGEGR--ARHSEAEATR------ARRRSRSYSPIRKRRRDSPSFMEPRRITSARKR 582
R +R S + R RRRS S SP+R RR +P R RKR
Sbjct: 1982 SRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKR 2037
Score = 61.2 bits (147), Expect = 3e-09
Identities = 67/209 (32%), Positives = 86/209 (41%), Gaps = 20/209 (9%)
Query: 455 GKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSS-RSPSKSRSRSA 513
G++ K+R R S H R + S SRS S S S RS ++SRSRS
Sbjct: 1812 GEKEKKRDSSLRSRSKRSKSSEHKSR---KRTSESRSRARKRSSKSKSHRSQTRSRSRSR 1868
Query: 514 EKRPHSPSRSPS-----------PKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRK 562
+R S SRS S + P R K E + + S + R R+RS +P R+
Sbjct: 1869 RRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRR 1928
Query: 563 RRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSH-SRSPSPGHSHGSYS 621
R +PS R R+ + SPS S S T S SR+PS S
Sbjct: 1929 SRSHTPSRRRRSRSVGRRRS----FSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRR 1984
Query: 622 SRSHGTRSRTRSPSRTPSPSYHSRSSSES 650
SR+ RSRT S R RS S S
Sbjct: 1985 SRTPSRRSRTPSRRRRSRSVVRRRSFSIS 2013
Score = 60.5 bits (145), Expect = 5e-09
Identities = 77/271 (28%), Positives = 110/271 (40%), Gaps = 55/271 (20%)
Query: 155 RTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKK-KKSVKKHRRDR 213
R+K SS + + + +RS K + S+ S S R++ +S K R R
Sbjct: 1825 RSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRR 1884
Query: 214 SDSGSRRKR--RHRSRSSKCKRKEK----NKEKKRPHTESPGRRSHRHS-SGSSHSPSLS 266
S S +RKR +HRS+S + KRK N++ R + +P RRS H+ S S S+
Sbjct: 1885 SVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVG 1944
Query: 267 SHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGG 326
S S SPSR S +T S+R SR+PS +RS
Sbjct: 1945 RRRSFSISPSRRS--------RTPSRR---SRTPS-----------------RRS----- 1971
Query: 327 RPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRR 386
+P + +PS R R P+R +PS R S R + R
Sbjct: 1972 -----RTPSRRSRTPSRRSR---------TPSRRSRTPSRRRRSRSVVRRRSFSISPVRL 2017
Query: 387 RRRRRRRRRSRSSASAPRRRGRRRPRPAPPR 417
RR R RR S + R+R R R P+
Sbjct: 2018 RRSRTPLRRRFSRSPIRRKRSRSSERGRSPK 2048
Score = 57.8 bits (138), Expect = 3e-08
Identities = 83/313 (26%), Positives = 113/313 (36%), Gaps = 34/313 (10%)
Query: 236 KNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSS 295
+++ P S R+ SS + D+ S+ + K+RD+G K + SS
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKN-KNRDKGEKEKKRDSS 1821
Query: 296 GSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSP-----SPRVRDKAA 350
S S S +R S R+ + S S S S R R K+
Sbjct: 1822 LRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSR 1881
Query: 351 AAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGR-- 408
+ K SP RS + R R+R+R SR + R R R
Sbjct: 1882 GRRSVSKEKRKRSPKHRS----------------KSRERKRKRSSSRDNRKTVRARSRTP 1925
Query: 409 -RRPRPAPP--RGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRA 465
RR R P R SRS+ R RS S S S R R +R++ R+
Sbjct: 1926 SRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRS 1985
Query: 466 R-PASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSK---SRSRSAEKRPHSPS 521
R P+ S +P RR RS P SR+P + SRS KR S
Sbjct: 1986 RTPSRRSRTPS---RRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSE 2042
Query: 522 RSPSPKKPLSRDK 534
R SPK+ DK
Sbjct: 2043 RGRSPKRLTDLDK 2055
Score = 51.6 bits (122), Expect = 2e-06
Identities = 75/266 (28%), Positives = 106/266 (39%), Gaps = 46/266 (17%)
Query: 155 RTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHR---- 210
R++ SS S + + + + RR R+ R S+ S G S ++K+K KHR
Sbjct: 1844 RSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSK-SRGRRSVSKEKRKRSPKHRSKSR 1902
Query: 211 ---RDRSDSGSRRK----------RRHRSRSSKCKRKEKNKEKKRPHTESPGRRSH---- 253
R RS S RK RR RS + +R+ ++ ++R + SP RRS
Sbjct: 1903 ERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSR 1962
Query: 254 --RHSSGSSHSPSLSSHYSD--SRSPSRLS--PKHRDEGRKTGSQRSSG------SRSPS 301
R S S +PS S SR+PSR S P R R +RS RS +
Sbjct: 1963 RSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRT 2022
Query: 302 PSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAA----AAAPTPP 357
P SP R S RS G P + DK + AA A P PP
Sbjct: 2023 PLRRRFSRSPIRRKRS--RSSERGRSP-KRLTDLDKAQLLEIAKANAAAMCAKAGVPLPP 2079
Query: 358 ARGKESPSPRSAPSSQGRGGRAAGGA 383
+ P P+ + + + +GGA
Sbjct: 2080 -----NLKPAPPPTIEEKVAKKSGGA 2100
Score = 33.9 bits (76), Expect = 0.48
Identities = 62/249 (24%), Positives = 85/249 (34%), Gaps = 57/249 (22%)
Query: 413 PAPPRGSSRSLSRARSSSDSGSG-RGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTS 471
P P + S ++L+ S +S G + P P E + G + + E RP
Sbjct: 1682 PLPVKESDQTLAALLSPKESSGGEKEVPPPPKETLPDSGFSANIEDINEAD-LVRPLLPK 1740
Query: 472 PSPGAHGRRGGPEGKSSSRSPGPHPRSWS---SSRSPSKSRSRSAEKRPHS-----PSRS 523
R G EG + G + S SS S S S EK +
Sbjct: 1741 DMERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTH 1800
Query: 524 PSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRP 583
KK +RDK GE + + +R++R S RKR +S S ARKR
Sbjct: 1801 EKSKKNKNRDK-GEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRS--------RARKR- 1850
Query: 584 IPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYH 643
SS+S RS+TRS SR+
Sbjct: 1851 -------------------------------------SSKSKSHRSQTRSRSRSRRRRRS 1873
Query: 644 SRSSSESGG 652
SRS S+S G
Sbjct: 1874 SRSRSKSRG 1882
Score = 30.4 bits (67), Expect = 5.4
Identities = 14/60 (23%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
Query: 201 KKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKK-RPHTESPGRRSHRHSSGS 259
+K + V + +++ ++H+ +K K+K+K KEKK + E ++ H G+
Sbjct: 88 RKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGN 147
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 82.4 bits (202), Expect = 1e-15
Identities = 88/276 (31%), Positives = 116/276 (42%), Gaps = 37/276 (13%)
Query: 173 KKKGGHRRSRKKRRL---ESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSS 229
K K H +S+K + E E SS R K+ +H+ + S SR + R RS S
Sbjct: 1795 KVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKS 1854
Query: 230 KCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKT 289
K R + T S R R S S S S S S+ + SPKHR + R+
Sbjct: 1855 KSHRSQ---------TRSRSRSRRRRRSSRSRSKS-RGRRSVSKEKRKRSPKHRSKSRER 1904
Query: 290 GSQRSSG--------SRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSP 341
+RSS +RS +PS S +P R +RS + G R + SP + +P
Sbjct: 1905 KRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRR----RRSRSVGRRRSFSISPSRRSRTP 1960
Query: 342 SPRVRDKAAAAAPTPPARGKESPSPRS-APSSQGRGGRAAGGAGRRRRRRRRRRRSRSSA 400
S R R P+R +PS RS PS + R RRRR R R RS +
Sbjct: 1961 SRRSR---------TPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFS 2011
Query: 401 SAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGR 436
+P R RR R R SRS R + S S GR
Sbjct: 2012 ISPVR--LRRSRTPLRRRFSRSPIRRKRSRSSERGR 2045
Score = 70.5 bits (171), Expect = 5e-12
Identities = 82/261 (31%), Positives = 108/261 (41%), Gaps = 35/261 (13%)
Query: 336 DKPSSPSPRVRDKAAAAAPTPPA-RGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRR 394
+K S R R K + ++ R ES S SS+ + R+ + R RRRRR
Sbjct: 1815 EKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSS 1874
Query: 395 RSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGH 454
RSRS S RR + R P+ S+S R R S S R
Sbjct: 1875 RSRSK-SRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTV--------------- 1918
Query: 455 GKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSS-SRSPSKSRSRSA 513
RA+ R P R S +PS R G +S S SP R+ S SR+PS+ RSR+
Sbjct: 1919 --RARSRTPSRRSRSHTPSRRRRSRSVGRR-RSFSISPSRRSRTPSRRSRTPSR-RSRTP 1974
Query: 514 EKRPHSPSRSPSPKKPLSRDKDGEGRARH---------SEAEATRAR---RRSRSYSPIR 561
+R +PSR SR R+R S R+R RR S SPIR
Sbjct: 1975 SRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIR 2034
Query: 562 KRR-RDSPSFMEPRRITSARK 581
++R R S P+R+T K
Sbjct: 2035 RKRSRSSERGRSPKRLTDLDK 2055
Score = 68.2 bits (165), Expect = 2e-11
Identities = 82/296 (27%), Positives = 113/296 (38%), Gaps = 33/296 (11%)
Query: 313 RNGGSGQRSGAHGGRPGSAHSP-----PDKPSSPSPRVRDKAAAAAPTPPARGKESPSPR 367
R G G + GR SA SP P++ S S +D K S +
Sbjct: 1749 RAGIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEK---SKK 1805
Query: 368 SAPSSQGRGGRAAGGAGRRRRRRR-------RRRRSRSSASAPRRRGRRRPRPAPPRGSS 420
+ +G + + R R +R R+R S S + A +R + + + R S
Sbjct: 1806 NKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRS 1865
Query: 421 RSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRR 480
RS R RSS RG E + H +++ER R R +S R
Sbjct: 1866 RSRRRRRSSRSRSKSRGRRSVSKE--KRKRSPKHRSKSRER-KRKRSSSRDNRKTVRARS 1922
Query: 481 GGPEGKSSSRSPGPHPRSWSSSR------SPSKSRSRSAEKRPHSPSRSPSPKKPLSRDK 534
P +S S +P RS S R SPS+ RSR+ +R +PSR SR
Sbjct: 1923 RTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSR-RSRTPSRRSRTPSRRSRTPSRRSRTP 1981
Query: 535 DGEGR--ARHSEAEATR------ARRRSRSYSPIRKRRRDSPSFMEPRRITSARKR 582
R +R S + R RRRS S SP+R RR +P R RKR
Sbjct: 1982 SRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKR 2037
Score = 61.2 bits (147), Expect = 3e-09
Identities = 67/209 (32%), Positives = 86/209 (41%), Gaps = 20/209 (9%)
Query: 455 GKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSS-RSPSKSRSRSA 513
G++ K+R R S H R + S SRS S S S RS ++SRSRS
Sbjct: 1812 GEKEKKRDSSLRSRSKRSKSSEHKSR---KRTSESRSRARKRSSKSKSHRSQTRSRSRSR 1868
Query: 514 EKRPHSPSRSPS-----------PKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRK 562
+R S SRS S + P R K E + + S + R R+RS +P R+
Sbjct: 1869 RRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRR 1928
Query: 563 RRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSH-SRSPSPGHSHGSYS 621
R +PS R R+ + SPS S S T S SR+PS S
Sbjct: 1929 SRSHTPSRRRRSRSVGRRRS----FSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRR 1984
Query: 622 SRSHGTRSRTRSPSRTPSPSYHSRSSSES 650
SR+ RSRT S R RS S S
Sbjct: 1985 SRTPSRRSRTPSRRRRSRSVVRRRSFSIS 2013
Score = 60.5 bits (145), Expect = 5e-09
Identities = 77/271 (28%), Positives = 110/271 (40%), Gaps = 55/271 (20%)
Query: 155 RTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKK-KKSVKKHRRDR 213
R+K SS + + + +RS K + S+ S S R++ +S K R R
Sbjct: 1825 RSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRR 1884
Query: 214 SDSGSRRKR--RHRSRSSKCKRKEK----NKEKKRPHTESPGRRSHRHS-SGSSHSPSLS 266
S S +RKR +HRS+S + KRK N++ R + +P RRS H+ S S S+
Sbjct: 1885 SVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVG 1944
Query: 267 SHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGG 326
S S SPSR S +T S+R SR+PS +RS
Sbjct: 1945 RRRSFSISPSRRS--------RTPSRR---SRTPS-----------------RRS----- 1971
Query: 327 RPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRR 386
+P + +PS R R P+R +PS R S R + R
Sbjct: 1972 -----RTPSRRSRTPSRRSR---------TPSRRSRTPSRRRRSRSVVRRRSFSISPVRL 2017
Query: 387 RRRRRRRRRSRSSASAPRRRGRRRPRPAPPR 417
RR R RR S + R+R R R P+
Sbjct: 2018 RRSRTPLRRRFSRSPIRRKRSRSSERGRSPK 2048
Score = 57.8 bits (138), Expect = 3e-08
Identities = 83/313 (26%), Positives = 113/313 (36%), Gaps = 34/313 (10%)
Query: 236 KNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSS 295
+++ P S R+ SS + D+ S+ + K+RD+G K + SS
Sbjct: 1763 RDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKN-KNRDKGEKEKKRDSS 1821
Query: 296 GSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSP-----SPRVRDKAA 350
S S S +R S R+ + S S S S R R K+
Sbjct: 1822 LRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSR 1881
Query: 351 AAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGR-- 408
+ K SP RS + R R+R+R SR + R R R
Sbjct: 1882 GRRSVSKEKRKRSPKHRS----------------KSRERKRKRSSSRDNRKTVRARSRTP 1925
Query: 409 -RRPRPAPP--RGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRA 465
RR R P R SRS+ R RS S S S R R +R++ R+
Sbjct: 1926 SRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRS 1985
Query: 466 R-PASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSK---SRSRSAEKRPHSPS 521
R P+ S +P RR RS P SR+P + SRS KR S
Sbjct: 1986 RTPSRRSRTPS---RRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSE 2042
Query: 522 RSPSPKKPLSRDK 534
R SPK+ DK
Sbjct: 2043 RGRSPKRLTDLDK 2055
Score = 51.6 bits (122), Expect = 2e-06
Identities = 75/266 (28%), Positives = 106/266 (39%), Gaps = 46/266 (17%)
Query: 155 RTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHR---- 210
R++ SS S + + + + RR R+ R S+ S G S ++K+K KHR
Sbjct: 1844 RSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSK-SRGRRSVSKEKRKRSPKHRSKSR 1902
Query: 211 ---RDRSDSGSRRK----------RRHRSRSSKCKRKEKNKEKKRPHTESPGRRSH---- 253
R RS S RK RR RS + +R+ ++ ++R + SP RRS
Sbjct: 1903 ERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSR 1962
Query: 254 --RHSSGSSHSPSLSSHYSD--SRSPSRLS--PKHRDEGRKTGSQRSSG------SRSPS 301
R S S +PS S SR+PSR S P R R +RS RS +
Sbjct: 1963 RSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRT 2022
Query: 302 PSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAA----AAAPTPP 357
P SP R S RS G P + DK + AA A P PP
Sbjct: 2023 PLRRRFSRSPIRRKRS--RSSERGRSP-KRLTDLDKAQLLEIAKANAAAMCAKAGVPLPP 2079
Query: 358 ARGKESPSPRSAPSSQGRGGRAAGGA 383
+ P P+ + + + +GGA
Sbjct: 2080 -----NLKPAPPPTIEEKVAKKSGGA 2100
Score = 33.9 bits (76), Expect = 0.48
Identities = 62/249 (24%), Positives = 85/249 (34%), Gaps = 57/249 (22%)
Query: 413 PAPPRGSSRSLSRARSSSDSGSG-RGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTS 471
P P + S ++L+ S +S G + P P E + G + + E RP
Sbjct: 1682 PLPVKESDQTLAALLSPKESSGGEKEVPPPPKETLPDSGFSANIEDINEAD-LVRPLLPK 1740
Query: 472 PSPGAHGRRGGPEGKSSSRSPGPHPRSWS---SSRSPSKSRSRSAEKRPHS-----PSRS 523
R G EG + G + S SS S S S EK +
Sbjct: 1741 DMERLTSLRAGIEGPLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTH 1800
Query: 524 PSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRP 583
KK +RDK GE + + +R++R S RKR +S S ARKR
Sbjct: 1801 EKSKKNKNRDK-GEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRS--------RARKR- 1850
Query: 584 IPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYH 643
SS+S RS+TRS SR+
Sbjct: 1851 -------------------------------------SSKSKSHRSQTRSRSRSRRRRRS 1873
Query: 644 SRSSSESGG 652
SRS S+S G
Sbjct: 1874 SRSRSKSRG 1882
Score = 30.4 bits (67), Expect = 5.4
Identities = 14/60 (23%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
Query: 201 KKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKK-RPHTESPGRRSHRHSSGS 259
+K + V + +++ ++H+ +K K+K+K KEKK + E ++ H G+
Sbjct: 88 RKSRCVSVQTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGN 147
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 80.9 bits (198), Expect = 3e-15
Identities = 118/470 (25%), Positives = 165/470 (35%), Gaps = 89/470 (18%)
Query: 157 KHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDS 216
K S S KKK KK H+R K K+ + + +++S
Sbjct: 666 KERSGKSHRHKKKKKHKKSSKHKR---------------------KHKADTEEKSSKAES 704
Query: 217 GSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPS 276
G + K+R + + K K ++ P E PG S S +P
Sbjct: 705 GEKSKKRKKRKRKKNKSSAPADSERGPKPEPPG--------------------SGSPAPP 744
Query: 277 RLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPD 336
R + +D+ SQR S P+ G SG + GG G S HGGR P
Sbjct: 745 RRRRRAQDD-----SQRRS---LPAEEGSSG---KKDEGGGGSSSQDHGGRKHKGELP-- 791
Query: 337 KPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRS 396
PSS R K ++ + S RS PSS A ++ +
Sbjct: 792 -PSSCQRRAGTKRSSRS-----------SHRSQPSSGDEDSDDASSHRLHQKSPSQYSEE 839
Query: 397 RSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGK 456
+ R R R S RS R+ SSS S + S+ + +
Sbjct: 840 EEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSD 899
Query: 457 RAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKR 516
R++ R+ + S + R K S S S S+S S+SRS + E R
Sbjct: 900 RSRRHSKRSHDSDDSDYASSKHR-----SKRHKYSSSDDDYSLSCSQSRSRSRSHTRE-R 953
Query: 517 PHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRI 576
S RS S SR K R S + + +RSRSYS R R SPS +
Sbjct: 954 SRSRGRSRSSSCSRSRSK------RRSRSTTAHSWQRSRSYSRDRSRSTRSPS-----QR 1002
Query: 577 TSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHG 626
+ +RKR + P S D+ RS SP H S R G
Sbjct: 1003 SGSRKRSWGHESPEERHSG---RRDFIRSKIYRSQSP---HYFRSGRGEG 1046
Score = 79.3 bits (194), Expect = 1e-14
Identities = 128/513 (24%), Positives = 180/513 (35%), Gaps = 98/513 (19%)
Query: 166 PPPKKKKKKKGGHRRSRKKR-RLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRH 224
P K K+ GG + R R+++ S + S L K++ H + D+G
Sbjct: 608 PGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSGLNKQEPG-GSHGSETEDTG------- 659
Query: 225 RSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRD 284
RS SK +R K SHRH H S S+ KH+
Sbjct: 660 RSLPSKKERSGK---------------SHRHKKKKKHKKS-----------SKHKRKHKA 693
Query: 285 EGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPR 344
+ + S+ SG +S ++ + + +P D P P
Sbjct: 694 DTEEKSSKAESGEKS-------------------KKRKKRKRKKNKSSAPADSERGPKPE 734
Query: 345 VRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGR---AAGGAGRRRRRRRRRRRSRSSAS 401
+ A P R ++ RS P+ +G G+ GG+ + R+ + +S
Sbjct: 735 PPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSS 794
Query: 402 APRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGR---GAPGPGPEPGSERGHGGHGKRA 458
RR G +R + R S+ S S D+ S R +P E E G R+
Sbjct: 795 CQRRAGTKRSSRSSHR--SQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRS 852
Query: 459 KERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWS-SSRSPSKSRSRSAEKRP 517
+ R R + S + SS +S RS+S S S RSR KR
Sbjct: 853 RSRSGRRHSSHRS----SRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRS 908
Query: 518 H---------SPSRSPSPKKPLSRD------KDGEGRARHSEAEATRARRRSRSYSPIRK 562
H S RS K S D R+R E +R+R RSRS S R
Sbjct: 909 HDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRS 968
Query: 563 RRRDSPSFMEPRRITSAR--KRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSY 620
R + R T+A +R Y R S+ S S RS SR S GH S
Sbjct: 969 RSK------RRSRSTTAHSWQRSRSYSRDRSRSTRS-----PSQRSGSRKRSWGHE--SP 1015
Query: 621 SSRSHGTRSRTRSP-SRTPSPSYHSRSSSESGG 652
R G R RS R+ SP Y E G
Sbjct: 1016 EERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPG 1048
Score = 56.2 bits (134), Expect = 9e-08
Identities = 113/454 (24%), Positives = 146/454 (32%), Gaps = 89/454 (19%)
Query: 140 DCDCPASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGG--------HRRSRKKRRLESEC 191
D SCY R Y +S S K+ HR R K +
Sbjct: 875 DASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDD 934
Query: 192 SCGSSSPLRKKKKSVKKHR-----RDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTE 246
S S R + +S + R R RS S SR + + RSRS+ H+
Sbjct: 935 YSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTA------------HSW 982
Query: 247 SPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSP---S 303
R R S S+ SPS S S RS SP+ R GR+ RS RS SP
Sbjct: 983 QRSRSYSRDRSRSTRSPSQRSG-SRKRSWGHESPEERHSGRR-DFIRSKIYRSQSPHYFR 1040
Query: 304 GGSGWGSPQRNGGSGQRSGAHG------------GRPGSAHSPPDKPS---------SPS 342
G G G +++ G G S A G G G SP DK S S
Sbjct: 1041 SGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDC-SPEDKNSVTAKLLLEKIQS 1099
Query: 343 PRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGA----------GRRRRRRRR 392
+V K + + K P + P QG G + G+ R+
Sbjct: 1100 RKVERKPSVSEEVQATPNKAGPKLKDPP--QGYFGPKLPPSLGNKPVLPLIGKLPATRKP 1157
Query: 393 RRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHG 452
++ S + P GSS +L + S+ GP +P E
Sbjct: 1158 NKKCEESGLERGEEQEQSETEEGPPGSSDALFGHQFPSEE-----TTGPLLDPPPEESKS 1212
Query: 453 GHGKRAKERPPRARPASTSPSPG----AHGRRGGP------EGKSSSRSPGPHPRSWSSS 502
G P PA + PG +H P E SS PGP SS
Sbjct: 1213 GEATADHPVAPLGTPAHSDCYPGDPTISHNYLPDPSDGDTLESLDSSSQPGP----VESS 1268
Query: 503 RSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDG 536
P A H PS +P P DG
Sbjct: 1269 LLP------IAPDLEHFPSYAPPSGDPSIESTDG 1296
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 80.5 bits (197), Expect = 5e-15
Identities = 121/458 (26%), Positives = 179/458 (39%), Gaps = 95/458 (20%)
Query: 162 SSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRK 221
+S SPP K++ KK G + K+RR E + + +K+ K R++ RR+
Sbjct: 122 ASDSPPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRR 181
Query: 222 ------RRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHS-----------SGSSHSPS 264
+ + R++ +R+ + EK + E+ +RS + + +G+ H S
Sbjct: 182 LEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKKTWAEIRQQRWSWAGALHHSS 241
Query: 265 LSSHYSDSR-SPSRLS-PKHRDEGRKTGSQRSSGSRSPSPSGG-----SGWGSP------ 311
S SR S S ++ PKH D +SS + SPS S W S
Sbjct: 242 PGHKTSGSRCSVSAVNLPKHVDSIINKRLSKSSATLWNSPSRNRSLQLSAWESSIVDRLM 301
Query: 312 ----------------QRNG-----GSGQRSGAHGGRPGS--AHSP-PDK--PSSPSPRV 345
RNG G G GR G+ A P PD+ PS+ P V
Sbjct: 302 TPTLSFLARSRSAVTLPRNGRDQGRGCDPGRGPTWGRAGASLARGPQPDRTHPSAAVP-V 360
Query: 346 RDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRA---AGGAGRRRRRR------------ 390
++A+A+P P S R AP+ + RG R AGG+ RRR
Sbjct: 361 CPRSASASPLTPCSVTRSVH-RCAPAGE-RGERRKPNAGGSPAPVRRRPEASPVQKKEKK 418
Query: 391 ---RRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSL--------SRARSSSDSGSGRGAP 439
R + +S+ + R +R+ PA PR + S+AR SS S S
Sbjct: 419 DKERENEKEKSALARERSLKKRQSLPASPRARLSASTASELSPKSKARPSSPSTSWHRPA 478
Query: 440 GPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSW 499
P P PG G +PP P T+ SP RR E K S + GP +S
Sbjct: 479 SPCPSPGP-------GHTLPPKPPS--PRGTTASPKGRVRRK-EEAKESPSAAGPEDKSQ 528
Query: 500 SSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGE 537
S R+ ++ S + SP+ SP+P P E
Sbjct: 529 SKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAE 566
Score = 51.6 bits (122), Expect = 2e-06
Identities = 95/484 (19%), Positives = 157/484 (32%), Gaps = 78/484 (16%)
Query: 170 KKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSS 229
+++K G + +RR E+ SP++KK+K K+ ++ S R+R + R S
Sbjct: 390 ERRKPNAGGSPAPVRRRPEA-------SPVQKKEKKDKERENEKEKSALARERSLKKRQS 442
Query: 230 KCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPS-----RLSPKHRD 284
SP S SPS S H S PS L PK
Sbjct: 443 LPASPRARLSASTASELSP------KSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPS 496
Query: 285 EGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPR 344
T S + R P+ S +R+ A P SP+P
Sbjct: 497 PRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPA 556
Query: 345 VRDKAAAAAPTPP----ARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSA 400
K A TP +P+P PS G A R +RR+ R +
Sbjct: 557 PPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAREQRER 616
Query: 401 SAPRRR--GRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRA 458
RR R R + + + +RA +++ +R
Sbjct: 617 EEQERRLQAERDKRMREEQLAREAEARAEREAEA-----------------------RRR 653
Query: 459 KERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPH 518
+E+ R + + + + + + +RS ++ + E+ H
Sbjct: 654 EEQEAREK----------------AQAEQEEQERLQKQKEEAEARSREEAERQRLEREKH 697
Query: 519 SPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITS 578
+ ++ R ++ R R SE T+ ++ S K + S EP +
Sbjct: 698 FQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDS-------KEANANGSSPEPVKAVE 750
Query: 579 AR-----KRPIPYYRPSPSSSSSCLSSDYSTRS--HSRSPSPGHSHGSYSSRS-HGTRSR 630
AR K + P P L S S + P P H +S+ G +S
Sbjct: 751 ARSPGLQKEAVQKEEPIPQEPQWSLPSKELPASLVNGLQPLPAHQENGFSTNGPSGDKSL 810
Query: 631 TRSP 634
+R+P
Sbjct: 811 SRTP 814
Score = 45.1 bits (105), Expect = 2e-04
Identities = 53/190 (27%), Positives = 78/190 (41%), Gaps = 15/190 (7%)
Query: 464 RARPASTSPSPGAHGRRGGPEGKS-------SSRSPGPHP-RSWSSSRSPSKSRSRSAEK 515
R+R A T P G RG G+ +S + GP P R+ S+ P RS SA
Sbjct: 310 RSRSAVTLPRNGRDQGRGCDPGRGPTWGRAGASLARGPQPDRTHPSAAVPVCPRSASASP 369
Query: 516 -RPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPR 574
P S +RS P + GE R ++ RRR + +K ++D E
Sbjct: 370 LTPCSVTRSVHRCAPAG--ERGERRKPNAGGSPAPVRRRPEASPVQKKEKKDKERENEKE 427
Query: 575 RITSARKRPIPYYRPSPSSSSSCLS----SDYSTRSHSRSPSPGHSHGSYSSRSHGTRSR 630
+ AR+R + + P+S + LS S+ S +S +R SP S +S
Sbjct: 428 KSALARERSLKKRQSLPASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPG 487
Query: 631 TRSPSRTPSP 640
P + PSP
Sbjct: 488 HTLPPKPPSP 497
Score = 37.0 bits (84), Expect = 0.057
Identities = 58/254 (22%), Positives = 86/254 (33%), Gaps = 69/254 (27%)
Query: 317 SGQRSGAHGGRPGS--AHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQG 374
SG R+ G P + A +PP+ PR + + P PP +P P +
Sbjct: 3 SGPRAELGAGAPPAVVARTPPE------PRPSPEGDPSPPPPPMSALVPDTPPDTPPAM- 55
Query: 375 RGGRAAGGAGRRRRRRRRRRRSRSSASAPRR----RGRRRPRPAPPRGSSRSLSRARSSS 430
+ + SS P G+ PRPAPP+ S S S A+S
Sbjct: 56 -------------------KNATSSKQLPLEPESPSGQVGPRPAPPQEESPS-SEAKS-- 93
Query: 431 DSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSR 490
G P GP RPPR S+ PSP A P K +
Sbjct: 94 ---RGPTPPAMGPRDA--------------RPPR---RSSQPSPTAVPASDSPPTKQEVK 133
Query: 491 SPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRA 550
G R + A++R ++ + KK + +K+ + +A + R
Sbjct: 134 KAG--------------ERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERR 179
Query: 551 RRRSRSYSPIRKRR 564
RR +RR
Sbjct: 180 RRLEEQRLKAEQRR 193
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 77.8 bits (190), Expect = 3e-14
Identities = 119/513 (23%), Positives = 177/513 (34%), Gaps = 61/513 (11%)
Query: 168 PKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGS-------RR 220
PK K KK+ KKR S S SSS S + D SDS S +R
Sbjct: 179 PKSKVKKE------EKKRHKSSSSSSSSSSD--SDSSSDSQSSSDSSDSESATEEKSKKR 230
Query: 221 KRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSH-SPSLSSHYSDSRSPSRLS 279
K++HR S K K+++K ++K + S + + S P ++R R S
Sbjct: 231 KKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKS 290
Query: 280 PKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRS--GAHGGRPGSAHSPPDK 337
P DE + +R R +P P S QR GR P
Sbjct: 291 PPKADEKERKNRERER-ERECNP--------PNSQPASYQRRLLVTRSGRKIKGRGPRRY 341
Query: 338 PSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSR 397
+ R RD+ + P R + + R SS G R G + +RS
Sbjct: 342 RTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSS---GERWIKGDKSELNEIKENQRSP 398
Query: 398 SSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKR 457
+ R +P R + + + + + R + + +
Sbjct: 399 VRVKERKITDHRNVSESPNRKNEKE-KKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAK 457
Query: 458 AKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPG------PHPRSWSSSRSPSKSRSR 511
+K R + + H R E + SRS G S S+ + RSR
Sbjct: 458 SKSRSKSKEKSKSKERDSKHNRN--EEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSR 515
Query: 512 SAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFM 571
S EK S+S S++KD ++R E + T+ + S + R R RD +
Sbjct: 516 SKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRV 575
Query: 572 EPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRS----PSPGHSHG--------- 618
R R R Y+R +Y R SRS PG S
Sbjct: 576 RSRTHDRDRSRSKEYHR--------YREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRD 627
Query: 619 SYSSRSHGTRSRTRSPSRT-PSPSYHSRSSSES 650
S SS ++SR + R S S H + +SES
Sbjct: 628 SRSSEREESQSRNKDKYRNQESKSSHRKENSES 660
Score = 66.6 bits (161), Expect = 7e-11
Identities = 109/510 (21%), Positives = 180/510 (35%), Gaps = 48/510 (9%)
Query: 160 SSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSR 219
SS S S +K KK+K HR++ +K + E +KK+K KK S++ +
Sbjct: 216 SSDSESATEEKSKKRKKKHRKNSRKHKKE-----------KKKRKKSKKSASSESEAENL 264
Query: 220 RKR--------------RHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSL 265
+ +R K K KE+K E + +S +S+ L
Sbjct: 265 EAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRL 324
Query: 266 SSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHG 325
S + R ++R R R S +P + + SG+R
Sbjct: 325 LVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGER--WIK 382
Query: 326 GRPGSAHSPPDKPSSP----SPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAG 381
G + + SP ++ D + KE +S+ R R
Sbjct: 383 GDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNS 442
Query: 382 GAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSS-DSGSGRGAPG 440
+ + + ++R S S + + + + R + + R+RS D + +
Sbjct: 443 EKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEK 502
Query: 441 PGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHP-RSW 499
G ++ +++K+ ++ S S RR + + G H S
Sbjct: 503 QSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSK-EKDRRAQSRSRECDITKGKHSYNSR 561
Query: 500 SSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSP 559
+ RS S+ RSR R H RS S + R+++ R R E RSRS
Sbjct: 562 TRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRS-KD 620
Query: 560 IRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGS 619
R+RRRDS S R + +R + YR S SS ++ S R S H S
Sbjct: 621 RRRRRRDSRS--SEREESQSRNK--DKYRNQESKSS---HRKENSESEKRMYSKSRDHNS 673
Query: 620 YSSRSHGTRSRTRSPSRTPSPSYHSRSSSE 649
SR + R SP + SS+
Sbjct: 674 ------SNNSREKKADRDQSPFSKIKQSSQ 697
Score = 56.6 bits (135), Expect = 7e-08
Identities = 73/299 (24%), Positives = 109/299 (36%), Gaps = 45/299 (15%)
Query: 156 TKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSD 215
T H + S + +K+KK H+ + K+R + +S K K VKK + +S
Sbjct: 407 TDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRR-----NSEKDDKYKNKVKKRAKSKSR 461
Query: 216 SGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSP 275
S S+ K + + R SK R E+KR + S GR S S SRS
Sbjct: 462 SKSKEKSKSKERDSKHNR----NEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSK 517
Query: 276 SR---LSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAH 332
+ L K + ++ ++S S G N + +RS +
Sbjct: 518 EKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSR-------- 569
Query: 333 SPPDKPSSPSPRVRDKAAAAAPTPPARGKE-----SPSPRSAPSSQGRGGRAAGGAGRRR 387
D+ R D+ +R KE R S+ R R G R +
Sbjct: 570 ---DRSRRVRSRTHDR-------DRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSK 619
Query: 388 RRRRRRRRSRSS---ASAPRRRGRRR-------PRPAPPRGSSRSLSRARSSSDSGSGR 436
RRRRRR SRSS S R + + R R R S++R + S + R
Sbjct: 620 DRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSR 678
Score = 42.7 bits (99), Expect = 0.001
Identities = 30/130 (23%), Positives = 55/130 (42%), Gaps = 4/130 (3%)
Query: 154 YRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDR 213
YR + S S P + + K RR R R E E S + + ++S HR++
Sbjct: 598 YRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKEN 657
Query: 214 SDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSR 273
S+S R + R +S ++EKK +SP + + S + S+ + D +
Sbjct: 658 SESEKRMYSKSRDHNS----SNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEK 713
Query: 274 SPSRLSPKHR 283
S + +++
Sbjct: 714 IRSSVEKENQ 723
Score = 31.6 bits (70), Expect = 2.4
Identities = 27/118 (22%), Positives = 52/118 (44%), Gaps = 14/118 (11%)
Query: 161 SSSASPPPKKKKKKKGGHRR--SRKKRRLESECSCGSSSPLRKKKKS---------VKKH 209
S S + + ++ K HR+ S ++R+ S+ +SS ++KK+ +K+
Sbjct: 636 SQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQS 695
Query: 210 RRDRSDSGS--RRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRR-SHRHSSGSSHSPS 264
+D S + K + RSS K +K+K ++ H ++ H S G+ S
Sbjct: 696 SQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESSPGTDEDKS 753
>gi|239754474 PREDICTED: similar to mucin [Homo sapiens]
Length = 417
Score = 76.3 bits (186), Expect = 9e-14
Identities = 101/423 (23%), Positives = 148/423 (34%), Gaps = 83/423 (19%)
Query: 211 RDRSDSGSRRKRRHRSRSSKCKRKEKNKE---KKRPHTESPGRRSHRHSSGSSHSPSLSS 267
R + RK R S + EK K +++P + G R SGSS PS
Sbjct: 4 RQKEQDTRLRKLRESSEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSS--PSADQ 61
Query: 268 HYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGR 327
+ R + D+ R + + + S G +R Q +G G R
Sbjct: 62 QGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQR 121
Query: 328 PGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRR 387
GS SP + R++ AAAAP P +RG + + + R AGG G+RR
Sbjct: 122 RGSRSSP--SADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQR----RPAGGTGQRR 175
Query: 388 ----------RRRRRRRRSRSSASAPRRRG----RRRP-----RPAPPRG------SSRS 422
+ + R ++A AP RG +R+P RPA G SS S
Sbjct: 176 GSGSSPSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCRPAGGTGQRRGSRSSPS 235
Query: 423 LSRARSSSDSGSGRGAPGP----------GPEPGSERGHGGHGKRA-------------- 458
+ R+ AP P P+ R GG G+R
Sbjct: 236 ADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRRGSGYSPSADQQGAQ 295
Query: 459 -KERPPRARPASTSPS---------------PGAHGRRGGPEGKSSSRSPGPHPRSWSSS 502
+E A PA TS G G+R G SS+ G R ++
Sbjct: 296 DREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSGCSSSANQQGAQDREEEAA 355
Query: 503 RS--PSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPI 560
+ P+ S R+ +++P P R P+ R G A+ RA+ R
Sbjct: 356 AAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRR-----GSGSSPSADQQRAQDREEEVRKW 410
Query: 561 RKR 563
+KR
Sbjct: 411 KKR 413
Score = 65.5 bits (158), Expect = 2e-10
Identities = 91/381 (23%), Positives = 138/381 (36%), Gaps = 56/381 (14%)
Query: 122 GAEPGLEYAPFDDDDGPVDCDCPASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRS 181
G G +P D G D + A+ R + +A+ P GHR +
Sbjct: 48 GQRRGSGSSPSADQQGAQDREEEAAAAPAADQQRAQDREEEAAAAPVPTSS----GHR-T 102
Query: 182 RKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKK 241
K++RL+ +C + R+ +S + R+ +S+ R EK K ++
Sbjct: 103 EKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRK-RQ 161
Query: 242 RPHTESPGRRSHRHSSGSSHSPSLSSHYSDSR------SPSRLSPKHRDEGRK------- 288
+P G R SGSS PS + R +P+ S HR E RK
Sbjct: 162 QPQRRPAGGTGQRRGSGSS--PSADQQGAQDREEEAAAAPAPTSRGHRTEKRKPQQPQCR 219
Query: 289 ----TGSQRSSGSR-----------------SPSPSGGSGWGSPQRNGGSGQR--SGAHG 325
TG +R S S +P+P+ G + +R QR +G G
Sbjct: 220 PAGGTGQRRGSRSSPSADQQRAQDREEEAAAAPAPTS-RGHRTEKRKPQQPQRRPAGGTG 278
Query: 326 GRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGR 385
R GS +SP + R++ AAAAP P + G + + + AGG G+
Sbjct: 279 QRRGSGYSP--SADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQC----QPAGGTGQ 332
Query: 386 RRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEP 445
RR SSA+ + R A P +S + R A G G
Sbjct: 333 RRGSG-----CSSSANQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRR 387
Query: 446 GSERGHGGHGKRAKERPPRAR 466
GS +RA++R R
Sbjct: 388 GSGSSPSADQQRAQDREEEVR 408
Score = 56.2 bits (134), Expect = 9e-08
Identities = 90/394 (22%), Positives = 137/394 (34%), Gaps = 96/394 (24%)
Query: 37 EELRAAEPGLVKRAHREILDHERKRRVELKCMEL--------------QEMMEEQGYSEE 82
EE AA P HR E+++R++L+C + Q EE
Sbjct: 86 EEEAAAAPVPTSSGHRT----EKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDREEE 141
Query: 83 EIRQKVGTFRQMLMEKEGVLTREDRPGGHIVAETPRLTEGAEPGLEYAPFDDDDGPVDCD 142
V T R EK + RP G G G +P D G D +
Sbjct: 142 AAAAPVPTSRGHRTEKRKRQQPQRRPAGGT---------GQRRGSGSSPSADQQGAQDRE 192
Query: 143 CPASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKK 202
++A+P P + GHR ++K + + +C + R+
Sbjct: 193 -----------------EEAAAAPAPTSR-----GHRTEKRKPQ-QPQCRPAGGTGQRRG 229
Query: 203 KKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHS 262
+S + R+ + +S+ R EK K ++ + G R GS +S
Sbjct: 230 SRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGTGQRR---GSGYS 286
Query: 263 PSLSSHYSDSR------SPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGG 316
PS + R +P+ S HR E RK + Q GG
Sbjct: 287 PSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQC-----------------QPAGG 329
Query: 317 SGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRG 376
+GQR G+ + D R++ AAAAP P + G + + P R
Sbjct: 330 TGQRRGSGCSSSANQQGAQD---------REEEAAAAPVPTSSGHR--TEKRKPQQPQR- 377
Query: 377 GRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRR 410
R A G G +RR S SS SA ++R + R
Sbjct: 378 -RPAAGTG-------QRRGSGSSPSADQQRAQDR 403
Score = 30.0 bits (66), Expect = 7.0
Identities = 49/247 (19%), Positives = 85/247 (34%), Gaps = 47/247 (19%)
Query: 29 SGTWPRAE-------EELRAAEPGLVKRAHREILDHERKRRVELKCMEL----------- 70
SG+ P A+ EE AA P R HR E+++ + +C
Sbjct: 177 SGSSPSADQQGAQDREEEAAAAPAPTSRGHRT----EKRKPQQPQCRPAGGTGQRRGSRS 232
Query: 71 ---QEMMEEQGYSEEEIRQKVGTFRQMLMEKEGVLTREDRPGGHIVAETPRLTEGAEPGL 127
+ Q EE T R EK + RP G G G
Sbjct: 233 SPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPAGGT---------GQRRGS 283
Query: 128 EYAPFDDDDGPVDCD-----CPASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSR 182
Y+P D G D + PA GHR + K P +++ G S
Sbjct: 284 GYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQ-CQPAGGTGQRRGSGCSSSA 342
Query: 183 KKRRLESECSCGSSSPL-------RKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKE 235
++ + +++P+ +K+K + RR + +G RR + + + ++
Sbjct: 343 NQQGAQDREEEAAAAPVPTSSGHRTEKRKPQQPQRRPAAGTGQRRGSGSSPSADQQRAQD 402
Query: 236 KNKEKKR 242
+ +E ++
Sbjct: 403 REEEVRK 409
>gi|42821110 hypothetical protein LOC340602 [Homo sapiens]
Length = 503
Score = 76.3 bits (186), Expect = 9e-14
Identities = 104/391 (26%), Positives = 142/391 (36%), Gaps = 39/391 (9%)
Query: 267 SHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGG 326
S D RSP + EG GSQ + G + + + G S +R
Sbjct: 98 SDRQDCRSPHEVFGCVVPEG---GSQAAVGPQKATGHADEHLAQTKSPGNSRRRKQPCRN 154
Query: 327 RPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRR 386
+ A PP + P P + P G + S + P G A
Sbjct: 155 QAAPAQKPPGRRLFPEPLPPSSPGFRPSSYPCSGASTSSQATQP-----GPALLSHASEA 209
Query: 387 RRRRRRR-------RRSRSSASAPRRRG-RRRPRPAPPRGSSRSLSRARSSSDSGSGRGA 438
R R R R R+S P RG +P PA P ++ L AR S +S G
Sbjct: 210 RPATRSRITLVASALRRRASGPGPVIRGCTAQPGPAFPHRATH-LDPARLSPESAPGPAR 268
Query: 439 PGPGPEPGSER----GHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGP 494
G PG R G +R ++ P + P +PG+ RRG +PGP
Sbjct: 269 RGRASVPGPARRGCDSAPGPARRGRDSAPVSAPRGRDSAPGS-ARRG------RDSAPGP 321
Query: 495 HPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARR-- 552
R ++RS + RS S SRS + L + G A + + T + R
Sbjct: 322 ALRV-RTARSDAGHRSTSTTPGTGLRSRSTQQRSALLSRRSLSGSADENPSCGTGSERLA 380
Query: 553 ---RSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSR 609
RS S P R P + R S+ P ++ P P SS Y++ S S
Sbjct: 381 FQSRSGSPDPEVPSRASPPVWHAVRMRASSPSPPGRFFLPIPQQWDESSSSSYASNSSSP 440
Query: 610 SPSPGHSHGSYSSRSHGTRSRTRSPSRTPSP 640
S SPG S S S G RS + TPSP
Sbjct: 441 SRSPGLSPSSPSPEFLGLRSIS-----TPSP 466
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 71.6 bits (174), Expect = 2e-12
Identities = 74/292 (25%), Positives = 101/292 (34%), Gaps = 61/292 (20%)
Query: 260 SHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQ 319
S + SL+ S SPS +S K + G+Q R+P P G G P + G Q
Sbjct: 14 SSAQSLNEDVSQEESPSVISGKPEGRRPQGGNQPQ---RTPPPPGKPE-GRPPQGGNQSQ 69
Query: 320 RSGAHGGRP--------GSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGK-ESPSPRSAP 370
G+P + PP +P P + + PP GK E P P+
Sbjct: 70 GPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGN 129
Query: 371 SSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSS 430
SQG R G + S P R G+ P PP+G ++S
Sbjct: 130 QSQGPPPRPGKPEGPPPQG------GNQSQGPPPRPGK--PEGPPPQGGNQS-------- 173
Query: 431 DSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSR 490
GP P PG G G + PP P PG + GP + ++
Sbjct: 174 --------QGPPPHPGKPEGPPPQGGNQSQGPP--------PRPG---KPEGPPPQGGNQ 214
Query: 491 SPGPHPRSWSSSRSPSKSRSRSAEKRPH-------------SPSRSPSPKKP 529
S GP PR PS+ ++ PH P R P P +P
Sbjct: 215 SQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRP 266
Score = 64.3 bits (155), Expect = 3e-10
Identities = 69/278 (24%), Positives = 97/278 (34%), Gaps = 36/278 (12%)
Query: 262 SPSLSSHYSDSRSPSRLS-------PKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRN 314
SPS+ S + R P + P + EGR Q + S+ P P G G P +
Sbjct: 28 SPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPP--QGGNQSQGPPPRPGKPEGPPPQG 85
Query: 315 GGSGQ----RSGAHGGRP----GSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGK-ESPS 365
G Q R G G+P + PP +P P + PP GK E P
Sbjct: 86 GNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPP 145
Query: 366 PRSAPSSQG---RGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRR-----PRPA--- 414
P+ SQG R G+ G + + + P +G + PRP
Sbjct: 146 PQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPE 205
Query: 415 --PPRGSSRSLSRAR-----SSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARP 467
PP+G ++S S G GP P PG +G +RPP
Sbjct: 206 GPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGR 265
Query: 468 ASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSP 505
P PG + ++ P + P P P+ R P
Sbjct: 266 PQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPP 303
Score = 35.0 bits (79), Expect = 0.22
Identities = 24/80 (30%), Positives = 29/80 (36%), Gaps = 2/80 (2%)
Query: 291 SQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAA 350
SQ + + P P G G P + G QR G RP P P P P K
Sbjct: 230 SQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPG-RPQGPPPPGGNPQQPLPPPAGK-P 287
Query: 351 AAAPTPPARGKESPSPRSAP 370
P PP G+ P+ P
Sbjct: 288 QGPPPPPQGGRPHRPPQGQP 307
Score = 32.0 bits (71), Expect = 1.8
Identities = 27/104 (25%), Positives = 41/104 (39%), Gaps = 13/104 (12%)
Query: 422 SLSRARSSSDSGSGRGAPGP-GPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRR 480
+LS A+S ++ S +P +P R GG+ +P T P PG R
Sbjct: 12 ALSSAQSLNEDVSQEESPSVISGKPEGRRPQGGN-----------QPQRTPPPPGKPEGR 60
Query: 481 GGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSP 524
P+G + S+ P P P ++S+ RP P P
Sbjct: 61 P-PQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQP 103
>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
Length = 629
Score = 70.9 bits (172), Expect = 4e-12
Identities = 108/422 (25%), Positives = 147/422 (34%), Gaps = 103/422 (24%)
Query: 284 DEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGS-AHSPPDKPSSPS 342
++ TG S S SG SG S R G S R RP S + P P
Sbjct: 119 EDPSSTGGPDSPPSTFCGDSGFSGSSSYGRLGPSEPRGIYASERPKSLGDASPSAPEVVG 178
Query: 343 PRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRA----------------------- 379
R + +AP P A G P S+ + R G
Sbjct: 179 ARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPTD 238
Query: 380 ---AGGAGR----------RRRRRRRRRRSRSSASA----PRRRGRRRPRP---APPRGS 419
AGGAGR RRRRRR + R+S PRR+ R RP +P GS
Sbjct: 239 SPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGS 298
Query: 420 SR-----SLSR-----------ARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPP 463
+R SL R +R+ + S AP P P + + P
Sbjct: 299 ARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPS--------PPDSPA 350
Query: 464 RARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRS 523
R PGA G G+++ R P P R S +SP + R R+A +R
Sbjct: 351 EGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRR------- 403
Query: 524 PSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKR- 582
R + GR + RAR+ SRS S R S P + +A +
Sbjct: 404 -------GRMAEASGR-----RGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREE 451
Query: 583 ---PIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSP-SRTP 638
P P P+P+ ++ S RS + + + G R R R+P +R P
Sbjct: 452 PRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDA-----------ADGRRVRPRAPAARVP 500
Query: 639 SP 640
P
Sbjct: 501 GP 502
Score = 66.2 bits (160), Expect = 9e-11
Identities = 95/353 (26%), Positives = 124/353 (35%), Gaps = 71/353 (20%)
Query: 242 RPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPS 301
RP T+SP S L R SP D G + Q S R P
Sbjct: 234 RPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRR--QNSVRQRPPD 291
Query: 302 PSGGSGWGSPQRNGGSGQRSGAHGGRPGS----------------------AHSPPDKPS 339
S G P R S +R G H P + A SPPD P+
Sbjct: 292 ASPSPGSARPAREP-SLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPA 350
Query: 340 --------------SPSPRVRDKAAAAAPTPPARGK--ESPSPRSAPSSQGRGGRAAGGA 383
+ + + +AA P P RG+ E PR P + GR GR A +
Sbjct: 351 EGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEAS 410
Query: 384 GRR---RRRRRRRRRSRSS----ASA-----PRRRGRRRPRPAPPRGSSRSLSRARSSSD 431
GRR R R+ R +S +S ASA P+ R P PPR R + ++
Sbjct: 411 GRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAEREEPRPPR-PRRGPAPTLAAQA 469
Query: 432 SGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRR-----GGPEGK 486
+GS R ++ G+R + R P AR PSP A RR G + +
Sbjct: 470 AGSCRRWRSTAEIDAAD------GRRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSE 523
Query: 487 SSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPK-KPLSRDKDGEG 538
S+ GP R R P+ + S S SP S D DG G
Sbjct: 524 CSAGRLGPLGR-----RGPAGGVGGGYGESESSASEGESPAFSSASSDSDGSG 571
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 70.5 bits (171), Expect = 5e-12
Identities = 68/270 (25%), Positives = 96/270 (35%), Gaps = 54/270 (20%)
Query: 290 GSQRSSGSRSPS-------PSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPS 342
G +S SRSP P GG+ P G Q GG PP KP P
Sbjct: 166 GDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 225
Query: 343 PRVRDKAAAAAPTP------PARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRS 396
P+ +K+ +A P P +G P P + +G GG
Sbjct: 226 PQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG-------------- 271
Query: 397 RSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAP--------GPGPEPGSE 448
+ P G+ P+ PP+G S+S S S S G +G P GP P PG
Sbjct: 272 -NKPQGPPPPGK--PQGPPPQGGSKSRS---SRSPPGKPQGPPPQGGNQPQGPPPPPGKP 325
Query: 449 RGHGGHG-KRAKERPPRARPASTSPSPGAHGRRG--------GPEGKSSSRSPGPHPRSW 499
+G G + + PP +P P G+ R GP + + GP P +
Sbjct: 326 QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAG 385
Query: 500 SSSRSPSKSRSRSAEKRPHSPSRSPSPKKP 529
+ + P + +P P R P +P
Sbjct: 386 GNPQQPQAPPA----GQPQGPPRPPQGGRP 411
Score = 62.0 bits (149), Expect = 2e-09
Identities = 59/243 (24%), Positives = 83/243 (34%), Gaps = 33/243 (13%)
Query: 295 SGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAP 354
S SPS G+ G+P + G +P SPP KP P P+ ++ P
Sbjct: 24 SQEESPSLIAGNPQGAPPQGGN----------KPQGPPSPPGKPQGPPPQGGNQ--PQGP 71
Query: 355 TPPARGKESPSPRSAPSSQG--RGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPR 412
PP + P P+ QG G+ G + + R R P + G +
Sbjct: 72 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG 131
Query: 413 PAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERG--HGGHGKRAKERPPRARPAST 470
P PP G + G P P PG +G G K R P +P
Sbjct: 132 PPPPPG--------KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGP 183
Query: 471 SPS--------PGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSP-SKSRSRSAEKRPHSPS 521
P P G+ GP + ++ GP P P ++S+SA P P
Sbjct: 184 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQ 243
Query: 522 RSP 524
P
Sbjct: 244 GPP 246
Score = 52.0 bits (123), Expect = 2e-06
Identities = 54/220 (24%), Positives = 76/220 (34%), Gaps = 41/220 (18%)
Query: 271 DSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGS 330
D++S S SP + +G P P GG+ P G Q GG
Sbjct: 229 DNKSQSARSPPGKPQG-------------PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 275
Query: 331 AHSPPDKPSSPSPRVRDKAAAAAPT------PPARGKESPSPRSAPSSQGRGGRAAGGAG 384
PP KP P P+ K+ ++ PP +G P P + +G GG
Sbjct: 276 GPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG-- 333
Query: 385 RRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAP-GPGP 443
+ P G +P+ PP+G S+S S + S G +G P G
Sbjct: 334 -------------NKPQGPPPPG--KPQGPPPQGGSKSRS---ARSPPGKPQGPPQQEGN 375
Query: 444 EPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGP 483
P G + + PP +P P P GR P
Sbjct: 376 NPQGPPPPAGGNPQQPQAPPAGQPQG-PPRPPQGGRPSRP 414
Score = 37.4 bits (85), Expect = 0.044
Identities = 37/156 (23%), Positives = 55/156 (35%), Gaps = 37/156 (23%)
Query: 411 PRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKE--RPPRARPA 468
P+ APP+G ++ +G P P PG +G G + PP +P
Sbjct: 36 PQGAPPQGGNKP-------------QGPPSP---PGKPQGPPPQGGNQPQGPPPPPGKPQ 79
Query: 469 STSPSPGAHGRRGGPEGK--------SSSRSP--------GPHPRSWSSSRSPSKSRSRS 512
P G + P GK SRSP GP P+ + + P +
Sbjct: 80 GPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKP 139
Query: 513 AEKRP---HSPSRSPSPKKPLSRDKDGEGRARHSEA 545
P + P P P KP G+ ++R S +
Sbjct: 140 QGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRS 175
>gi|221139764 PHD and ring finger domains 1 [Homo sapiens]
Length = 1648
Score = 70.1 bits (170), Expect = 6e-12
Identities = 82/288 (28%), Positives = 113/288 (39%), Gaps = 44/288 (15%)
Query: 160 SSSSASPPPKKKKKKKGGHRRSRKKRRLES-ECSCGSSSPLRKKKKSVKKHRRDRSDSGS 218
+SSS S K+K+ H R+R R ES + S S+SP ++ RR RS + S
Sbjct: 995 TSSSRSRKKAKRKRVSREHGRTRSGTRSESRDRSSRSASP----SVGEERPRRQRSKAKS 1050
Query: 219 RRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSS--HYSDSRSPS 276
RR RS S + +++K K+K R H P S R S S SP SS HY S
Sbjct: 1051 RRSSSDRSSSRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYE-----S 1105
Query: 277 RLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPD 336
R K R R G R SP+ S +R H + +H PD
Sbjct: 1106 RKKKKRRSASRPRG-------RECSPT------------SSLERLCRHKHQRERSHERPD 1146
Query: 337 KPSSPS-PRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRR 395
+ S + PR R K + +P+ R +E PRS R R+
Sbjct: 1147 RKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREK----------WPQTRSHSPERKGA 1196
Query: 396 SRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGP 443
R ++ AP +G P R +L A S + + AP P
Sbjct: 1197 VREASPAPLAQGEPGREDLPTR--LPALGEAHVSPEVATADKAPLQAP 1242
Score = 69.3 bits (168), Expect = 1e-11
Identities = 80/298 (26%), Positives = 109/298 (36%), Gaps = 49/298 (16%)
Query: 335 PDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRR 394
P+ P SP PP+R + + S RS ++ + R + GR R R
Sbjct: 967 PEAPPSPDVLQAATHRVVELRPPSRSRSTSSSRSRKKAKRK--RVSREHGRTRSGTRSES 1024
Query: 395 RSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGH 454
R RSS SA G RPR + SR RSSSD S R
Sbjct: 1025 RDRSSRSASPSVGEERPRRQRSKAKSR-----RSSSDRSSSR------------------ 1061
Query: 455 GKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAE 514
+RAK + + + P H RR S SRS P S+ S K + RSA
Sbjct: 1062 -ERAKRKKAKDKSREHRRGPWGHSRR-----TSRSRSGSPGSSSYEHYESRKKKKRRSA- 1114
Query: 515 KRPHSPSRSPSP------KKPLSRDKDGEGRARHSEAEATRARRRSRSYSPI-------R 561
RP SP+ + R++ E R R RR+ RS SP
Sbjct: 1115 SRPRGRECSPTSSLERLCRHKHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEHRAREH 1174
Query: 562 KRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGS 619
+R R + + R + RK + P+P + D T R P+ G +H S
Sbjct: 1175 RRPRSREKWPQTRSHSPERKGAVREASPAPLAQGEPGREDLPT----RLPALGEAHVS 1228
Score = 62.0 bits (149), Expect = 2e-09
Identities = 116/486 (23%), Positives = 156/486 (32%), Gaps = 47/486 (9%)
Query: 149 RGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKK 208
R G R++ SS S P +++ R K RR S+ S RKK K +
Sbjct: 1015 RTRSGTRSESRDRSSRSASPSVGEERPRRQRSKAKSRRSSSDRSSSRERAKRKKAKDKSR 1074
Query: 209 HRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSH 268
R SRR R RS S E + +K+ S R R S +S L H
Sbjct: 1075 EHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKKKRRSASRPRGRECSPTSSLERLCRH 1134
Query: 269 YSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPS----------PSGGSGW-----GSPQR 313
R S P ++ +R SRSPS P W SP+R
Sbjct: 1135 -KHQRERSHERPDRKESVAWPRDRRKRRSRSPSSEHRAREHRRPRSREKWPQTRSHSPER 1193
Query: 314 NGGSGQRSGA--HGGRPGSAHSPPDKPS------SPSPRVRDKAAAAAPTPPARGKESPS 365
G + S A G PG P P+ SP DKA AP P
Sbjct: 1194 KGAVREASPAPLAQGEPGREDLPTRLPALGEAHVSPEVATADKAPLQAP-PVLEVAAECE 1252
Query: 366 PRSAPSSQGRGGRA--------AGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPR 417
P G A + + S+ S+P R +P PP
Sbjct: 1253 PDDLDLDYGDSVEAGHVFDDFSSDAVFIQLDDMSSPPSPESTDSSPERDFPLKP-ALPPA 1311
Query: 418 GSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGH----GGHGKRAKERPPRARPASTSPS 473
+ + + S P P PE G++ H K P PA S
Sbjct: 1312 SLAVAAIQREVSLMHDEDPSQPPPLPE-GTQEPHLLRPDAAEKAEAPSSPDVAPAGKEDS 1370
Query: 474 PGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRD 533
P A GR S P RS + + + + E +P+ +P+ PL R
Sbjct: 1371 PSASGRVQEAARPEEVVSQTPLLRSRALVKRVTWNLQ---ESESSAPAEDRAPRAPLHRP 1427
Query: 534 KDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSF--MEPRRITSARKRPIPYYRPSP 591
+ A E A R+ S P P F +P ++ S P P P
Sbjct: 1428 QKPREGAWDMEDVAPTGVRQVFSELPFPSHVLPEPGFPDTDPSQVYSPGLPPAP---AQP 1484
Query: 592 SSSSSC 597
SS C
Sbjct: 1485 SSIPPC 1490
Score = 58.5 bits (140), Expect = 2e-08
Identities = 119/472 (25%), Positives = 169/472 (35%), Gaps = 70/472 (14%)
Query: 206 VKKHRRDRSDSGSRRKRRH-RSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPS 264
+ K RRD D G RR +S + ++ R T PGR + S SS P
Sbjct: 681 IPKIRRD--DGGGRRDAAPAHGQSIEIPSACISRLTGREGTGQPGRGTRAESEASSRVP- 737
Query: 265 LSSHYSDSRSPSRLSPKHRDEGRKTGSQR-----SSGSRSP-SPSGGSGWGSP----QRN 314
R+ G TGS R S GS +P PS G G GS + N
Sbjct: 738 ------------------REPGVHTGSSRPPAPSSHGSLAPLGPSRGKGVGSTFESFRIN 779
Query: 315 GGSGQRSGAHGGRPGSAHS--PPD----KPSSPSPRVRDKAAAAA------PTPPARGKE 362
+ PG ++ P D + +PSP K P+ P G +
Sbjct: 780 IPGNMAHSSQLSSPGFCNTFRPVDDKEQRKENPSPLFSIKKTKQLRSEVYDPSDPT-GSD 838
Query: 363 SPSPRSAPSSQGRGGRAAG-----GAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPR 417
S +P S+P G G + + + + R +S + G P PP
Sbjct: 839 SSAPGSSPERSGPGLLPSEITRTISINSPKAQTVQAVRCVTSYTVESIFGTE---PEPPL 895
Query: 418 GSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAH 477
G S ++S+ R + + GA E +E G A+ R P +
Sbjct: 896 GPSSAMSKLRGAV---AAEGASDTEREEPTE----SQGLAARLRRPSPPEPWDEEDGASC 948
Query: 478 GRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGE 537
G E ++ + P + S + R E RP PSRS S SR K
Sbjct: 949 STFFGSEERTVTCVTVVEPEAPPSPDVLQAATHRVVELRP--PSRSRSTSSSRSRKK--- 1003
Query: 538 GRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSC 597
+ + E R R +RS S R R SPS E R R+R R S S SS
Sbjct: 1004 AKRKRVSREHGRTRSGTRSESRDRSSRSASPSVGEER---PRRQRSKAKSRRSSSDRSS- 1059
Query: 598 LSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSE 649
S + + R ++ S H G + +RSR+ SP + Y SR +
Sbjct: 1060 -SRERAKRKKAKDKSREHRRGPWGHSRRTSRSRSGSPGSSSYEHYESRKKKK 1110
Score = 33.1 bits (74), Expect = 0.83
Identities = 67/265 (25%), Positives = 84/265 (31%), Gaps = 45/265 (16%)
Query: 268 HYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGR 327
H S S R +P QR+SGS S G G P+ G G R
Sbjct: 525 HRDGSLSAKRAAP--------VSFQRNSGSLSRGEEGFKGCLQPRALPSGSPAQGPSGNR 576
Query: 328 P--------GSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKES---PSPRSAPSSQGRG 376
P G + +P +P VR AA AR + P R + S G
Sbjct: 577 PQSTGLSCQGRSRTPARTAGAP---VRLDLPAAPGAVQARNLSNGSVPGFRQSHSPWFNG 633
Query: 377 GR----AAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSR-ARSSSD 431
A + R + RS P +PAP R L R + D
Sbjct: 634 TNKHTLPLASAASKISSRDSKPPCRSVVPGPPL------KPAPRRTDISELPRIPKIRRD 687
Query: 432 SGSGR--GAPGPG-----PEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPE 484
G GR AP G P R G G R RA ++S P G G
Sbjct: 688 DGGGRRDAAPAHGQSIEIPSACISRLTGREGTGQPGRGTRAESEASSRVPREPGVHTG-- 745
Query: 485 GKSSSRSPGPHPRSWSSSRSPSKSR 509
SSR P P + PS+ +
Sbjct: 746 ---SSRPPAPSSHGSLAPLGPSRGK 767
>gi|167234419 thyroid hormone receptor associated protein 3 [Homo
sapiens]
Length = 955
Score = 70.1 bits (170), Expect = 6e-12
Identities = 94/377 (24%), Positives = 128/377 (33%), Gaps = 57/377 (15%)
Query: 202 KKKSVKKHRRDRSDSGSRR----KRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSS 257
K KS + R RS S SR K R RSRS RK + + R + SP R+
Sbjct: 6 KSKSGSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHP 65
Query: 258 GSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGS 317
+ H R P ++R G WG R G
Sbjct: 66 RVYQNRDFRGHNRGYRRPYYFRGRNR--------------------GFYPWGQYNRGGYG 105
Query: 318 GQRSG------AHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPS 371
RS A+ R G + S K SPSPR R + +S S RS S
Sbjct: 106 NYRSNWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHS--------RNSDKSSSDRSRRS 157
Query: 372 SQGRGGRAAGGAGRRRRRRRRRRRSRSSASAP-RRRGRRRPRPAPPRGSSRSLSRARSSS 430
S R +R+ + ++S S S P + G + A + S S+ +S
Sbjct: 158 SSSRSSSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKAS 217
Query: 431 DSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRAR-PASTSPSPGAHGRRGGPEGKSSS 489
+S P P+ G E PR R PA SP RR P S
Sbjct: 218 ESSK------PWPDATYGTGSASRASAVSELSPRERSPALKSPLQSVVVRRRSPR---PS 268
Query: 490 RSPGPHPRSWSSSRSPS--------KSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRAR 541
P P P S+S+ S +S + + S S SPS K P+ + G
Sbjct: 269 PVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKSPVGKSPPSTGSTY 328
Query: 542 HSEAEATRARRRSRSYS 558
S + A +Y+
Sbjct: 329 GSSQKEESAASGGAAYT 345
Score = 69.3 bits (168), Expect = 1e-11
Identities = 110/442 (24%), Positives = 163/442 (36%), Gaps = 73/442 (16%)
Query: 170 KKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHR-RDRSDSGSRRKR---RHR 225
K K K G R SR S S R + +S K R R RS S SR++R R R
Sbjct: 3 KTNKSKSGSRSSR------------SRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSR 50
Query: 226 SRS-SKCKRKEKNKEKKRPHTESPGR-------------------------------RSH 253
SRS S +E+N + + + G RS+
Sbjct: 51 SRSYSPAHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSN 110
Query: 254 RHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSR------SPSPSGGSG 307
+ ++SP S SRSP R SP R S +SS R S S S S
Sbjct: 111 WQNYRQAYSPRRGR--SRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSR 168
Query: 308 WGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSP- 366
S +R ++S + RP A + +++ + + + ES P
Sbjct: 169 VESSKRKSAKEKKSSSKDSRPSQAAG-----DNQGDEAKEQTFSGGTSQDTKASESSKPW 223
Query: 367 RSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRA 426
A G RA+ + R R +S + RRR PRP+P S LS
Sbjct: 224 PDATYGTGSASRASAVSELSPRERSPALKSPLQSVVVRRRS---PRPSPVPKPSPPLS-- 278
Query: 427 RSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGK 486
S+S GS + G G + G+ +G HG + P + P SP P G + +
Sbjct: 279 -STSQMGSTLPS-GAGYQSGTHQGQFDHGSGSLS-PSKKSPVGKSP-PSTGSTYGSSQKE 334
Query: 487 SSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRAR-HSEA 545
S+ S G +++ +K+ ++ K S G+G+ + S A
Sbjct: 335 ESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKIKEKGSFSDTGLGDGKMKSDSFA 394
Query: 546 EATRARRRSR-SYSPIRKRRRD 566
T + + R S SP R + RD
Sbjct: 395 PKTDSEKPFRGSQSPKRYKLRD 416
Score = 62.0 bits (149), Expect = 2e-09
Identities = 87/337 (25%), Positives = 125/337 (37%), Gaps = 49/337 (14%)
Query: 360 GKESPSPRSAPSSQGRG---GRAAGGAGRRRRRRRRRRRSRSSASAP-RRRGRRRPRPAP 415
G S RSA S+ R R+ + R R+RR RSRS + +P R R PR
Sbjct: 10 GSRSSRSRSASRSRSRSFSKSRSRSRSLSRSRKRRLSSRSRSRSYSPAHNRERNHPRVYQ 69
Query: 416 PRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGK--------RAKERPPRARP 467
R R +R GR G P + GG+G R P R R
Sbjct: 70 NR-DFRGHNRGYRRPYYFRGRNR---GFYPWGQYNRGGYGNYRSNWQNYRQAYSPRRGRS 125
Query: 468 ASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPS-----KSRSRSAEKRPHSPSR 522
S SP + R ++S +S R SSSRS S +S R + K S S+
Sbjct: 126 RSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSK 185
Query: 523 SPSPKKPLSRDKDGE--------GRARHSEAE-----------ATRARRRSRSYSPIRKR 563
P + ++ E G ++ ++A T + R+ + S + R
Sbjct: 186 DSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKPWPDATYGTGSASRASAVSELSPR 245
Query: 564 RRDSPSFMEPRRITSARK---RPIPYYRPSPSSSS-----SCLSSDYSTRSHSRSPSPGH 615
R SP+ P + R+ RP P +PSP SS S L S +S + H
Sbjct: 246 ER-SPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQGQFDH 304
Query: 616 SHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESGG 652
GS S ++ + + S S+ SGG
Sbjct: 305 GSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGG 341
Score = 50.8 bits (120), Expect = 4e-06
Identities = 60/176 (34%), Positives = 70/176 (39%), Gaps = 34/176 (19%)
Query: 501 SSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPI 560
S + SKS SRS+ R S SRS S K SR + S +R RSRSYSP
Sbjct: 2 SKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRS----LSRSRKRRLSSRSRSRSYSPA 57
Query: 561 RKRRRDSPSFMEPRRITS-ARKRPIPYYRPSPS------------------SSSSCLSSD 601
R R+ P + R R PYY + S+
Sbjct: 58 HNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRGGYGNYRSNWQNYRQA 117
Query: 602 YS-----TRSHS---RSPSP-GHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSS 648
YS +RS S RSPSP SH S +S RSR S SR S S HSR S
Sbjct: 118 YSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSR--SSSNHSRVES 171
Score = 50.4 bits (119), Expect = 5e-06
Identities = 73/311 (23%), Positives = 111/311 (35%), Gaps = 50/311 (16%)
Query: 150 GHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKR-RLESECSCGSSSP-LRKKKKSVK 207
G+ YR+ + A P + + + + RRS R R S S SSS R+ S
Sbjct: 103 GYGNYRSNWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSSRS 162
Query: 208 KHRRDRSDSGSRRKRRHRSRSSKCKRKEK----NKEKKRPHTESPGRRSHRHSSGSSHSP 263
R +S R+ + + SSK R + N+ + G S + S P
Sbjct: 163 SSNHSRVESSKRKSAKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDTKASESSKP 222
Query: 264 SLSSHY-----SDSRSPSRLSPKHRDEGRKTGSQ-----RSSGSRSPSPSGGSGWGSPQR 313
+ Y S + + S LSP+ R K+ Q R S SP P S +
Sbjct: 223 WPDATYGTGSASRASAVSELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQ 282
Query: 314 NG-----GSGQRSGAHGGR--PGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSP 366
G G+G +SG H G+ GS P K S +PP+ G
Sbjct: 283 MGSTLPSGAGYQSGTHQGQFDHGSGSLSPSKKS-----------PVGKSPPSTGS----- 326
Query: 367 RSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRA 426
+ SSQ A+GGA +R ++ ++ + + +
Sbjct: 327 -TYGSSQKEESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEK----------IKEK 375
Query: 427 RSSSDSGSGRG 437
S SD+G G G
Sbjct: 376 GSFSDTGLGDG 386
Score = 38.9 bits (89), Expect = 0.015
Identities = 36/155 (23%), Positives = 63/155 (40%), Gaps = 23/155 (14%)
Query: 169 KKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRS 228
++KK K+ +R + + ++S S S S R +K+ K H+ + R+ R RSRS
Sbjct: 723 RRKKHKERDLKRGKSRESVDSRDS--SHSRERSAEKTEKTHKGSKKQK-KHRRARDRSRS 779
Query: 229 SKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSR--LSPKHRDEG 286
S + + K +TE R ++ + SR ++ + P R G
Sbjct: 780 SSSSSQSSHSYKAEEYTEETEEREES-----------TTGFDKSRLGTKDFVGPSERGGG 828
Query: 287 RKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRS 321
R G+ + + G GWG +G + S
Sbjct: 829 RARGTFQFR-------ARGRGWGRGNYSGNNNNNS 856
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 68.9 bits (167), Expect = 1e-11
Identities = 105/458 (22%), Positives = 160/458 (34%), Gaps = 68/458 (14%)
Query: 170 KKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHR-RDRSDSGSRRKRRHRSRS 228
+++ ++ R R+KR+ E E + R++++ +HR RDR R + + R R
Sbjct: 54 RERNRQKERERRREKRQTERE-----TDRKRERRREKDRHRKRDRHRERQRDREKERERQ 108
Query: 229 SKCKR-----KEKNKEKKRP-HTESPGRRSH-RHSSGSSHSPSLSSHYSD---------- 271
+ +R KE+N++K+R TE G R R + G +
Sbjct: 109 TDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQ 168
Query: 272 -----SRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGG 326
+R R K+R E R+ QR +++ G R + +
Sbjct: 169 RQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERG-----RERERERETETETE 223
Query: 327 RPGSAHSPPDKPSSPSPRVRDKAA---AAAPTPPARGKESPSPRSAPSSQGRGGRAAGGA 383
R D+ + R R+K A A+ R KE R + R +
Sbjct: 224 RKRQTDRERDR-QRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQ 282
Query: 384 GRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGP 443
R+R+RR R + R+R R R R R R R R
Sbjct: 283 TDRKRQRRTERDRETERKRERQRERERER---ERNRKRERERER---------------- 323
Query: 444 EPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSR 503
E ER R KER R R T R+ G EG R R R
Sbjct: 324 ERERERQRETERDREKER-ERKRKRQTE-MDRERNRQTGREG----RRQAERERERERER 377
Query: 504 SPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGE-----GRARHSEAEATRARRRSRSYS 558
+R R +R R ++ +D+DG+ R R + E+ R R R R
Sbjct: 378 DRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRERE 437
Query: 559 PIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSS 596
+ R RD R+ RKR Y P P ++ S
Sbjct: 438 KQKGRERDRER-QTDRQAGRQRKRSTLYVNPPPRTARS 474
Score = 55.8 bits (133), Expect = 1e-07
Identities = 72/305 (23%), Positives = 111/305 (36%), Gaps = 39/305 (12%)
Query: 170 KKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSS 229
+ +++K R++ +KR+ +E + ++++ ++ R+R R + R R R
Sbjct: 272 RDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQR 331
Query: 230 KCKR-KEKNKEKKRP-----------HTESPGRRS-----------HRHSSGSSHSPSLS 266
+ +R +EK +E+KR T GRR R S+
Sbjct: 332 ETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERD 391
Query: 267 SHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGS-GWGSPQRNGGSGQRSGAHG 325
+ R + K RD R+T QR S G G ++ G R
Sbjct: 392 RDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTD 451
Query: 326 GRPGSAHSPPDKPSSPSPR-VRDKAAAAAPTPPARG---KESPSPRSAPSSQGRGGRAAG 381
+ G +P PR R + P P RG K SP A S++ GR A
Sbjct: 452 RQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAK 511
Query: 382 GAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGP 441
+ R R RRR R +G RP+ G+ LS+A S PGP
Sbjct: 512 AS---RGRVAGRRRWEPRLGEKRGQGGEGRRPSGGFGTENPLSQAPSV--------FPGP 560
Query: 442 GPEPG 446
PG
Sbjct: 561 RYTPG 565
Score = 48.5 bits (114), Expect = 2e-05
Identities = 68/346 (19%), Positives = 115/346 (33%), Gaps = 29/346 (8%)
Query: 155 RTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRS 214
R + + + + ++ +++ R++ ++R ++E S + K+ ++ RDR
Sbjct: 212 RERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDR- 270
Query: 215 DSGSRRKRRHRSRSSKCKRK---EKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSD 271
D R+K R R K +R+ ++ E+KR R R+
Sbjct: 271 DRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRK-RERERERERERER 329
Query: 272 SRSPSRLSPKHRDEGRKTGSQRS-SGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGS 330
R R K R+ RK ++ +R G + R A
Sbjct: 330 QRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERE 389
Query: 331 AHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRR 390
D+ + T R +E +GR G R R R+
Sbjct: 390 RDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQ 449
Query: 391 ------RRRRRS----------------RSSASAPRRRGRRRPRPAPPRGSSRSLSRARS 428
R+R+RS +S + P R R + P P+ +S R
Sbjct: 450 TDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRP 509
Query: 429 SSDS-GSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPS 473
+ S G G P G +RG GG G+R P S +PS
Sbjct: 510 AKASRGRVAGRRRWEPRLGEKRGQGGEGRRPSGGFGTENPLSQAPS 555
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 68.2 bits (165), Expect = 2e-11
Identities = 116/459 (25%), Positives = 156/459 (33%), Gaps = 90/459 (19%)
Query: 212 DRSDSGSR------RKRRHRSRSSKCK--RKEKNK--------EKKRPHTESPGRRSHRH 255
+RSD GS + RHR R + RKEK + E+++ TE + +
Sbjct: 399 ERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEF 458
Query: 256 SSGSSHSPSL------------SSHYSDSRSPSRLSPK-HRDEGRKTGSQRSSGSRSPSP 302
+S SL + + + S L PK E K G RS S S S
Sbjct: 459 IHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSS 518
Query: 303 SGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKE 362
S S S S S + G S+ S SSP R K + + +P + +
Sbjct: 519 SSNSRTSSTSSTVSSSSYSSSSGSSRTSSRS-----SSPK---RKKRHSRSRSPTIKARR 570
Query: 363 SPSPRSAPSSQGRGGRAAGGAGRRRRRRR----RRRRSRSSASAPRRRGRRRPRPAPPRG 418
S S + + RA RRR R R RR S S RRR R R R
Sbjct: 571 SRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNR 630
Query: 419 SSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHG 478
+SRS SR R D G + G+ H G K + + R+R
Sbjct: 631 ASRSRSRDRRKIDDQRGNLS-------GNSHKHKGEAKEQERKKERSRSID--------- 674
Query: 479 RRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEG 538
+ K R R +KR R K S+D +
Sbjct: 675 ---------------------KDRKKKDKEREREQDKRKEKQKREEKDFKFSSQD---DR 710
Query: 539 RARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCL 598
R E+E T +R S S IR R + T K+ SSS S
Sbjct: 711 LKRKRESERTFSRSGSISVKIIRHDSRQDSK----KSTTKDSKKHSGSDSSGRSSSESPG 766
Query: 599 SSDYST-----RSHSRSPSPGHSHGSYSSRSHGTRSRTR 632
SS S SRS G +SR H ++SR+R
Sbjct: 767 SSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
Score = 60.5 bits (145), Expect = 5e-09
Identities = 84/345 (24%), Positives = 128/345 (37%), Gaps = 32/345 (9%)
Query: 155 RTKHWSSSSASPPPKKKKKKKGGHRRS--------RKKRRLESECSCGSSSPLRKKKKSV 206
RT + ++S P + K+K+K G RS R S S SSS S
Sbjct: 484 RTPNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSS 543
Query: 207 KKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLS 266
+ R S +R R RS + K +R +R ES R S+ S+
Sbjct: 544 RTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIE 603
Query: 267 SHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGG 326
+RSPSR + R R + R+S SRS + + G SG
Sbjct: 604 RERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRD--------RRKIDDQRGNLSGNSHK 655
Query: 327 RPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRR 386
G A K +D+ R +E + + + + + R
Sbjct: 656 HKGEAKEQERKKERSRSIDKDR----KKKDKEREREQDKRKEKQKREEKDFKFSSQDDRL 711
Query: 387 RRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPG 446
+R+R R S S + R R + +++ S+ S SDS SGR + PG
Sbjct: 712 KRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKD-SKKHSGSDS-SGRSS---SESPG 766
Query: 447 SERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRS 491
S + K+AK +P +R S S + G++ + KS SRS
Sbjct: 767 SSK-----EKKAK-KPKHSRSRSVEKSQRS-GKKASRKHKSKSRS 804
Score = 55.1 bits (131), Expect = 2e-07
Identities = 60/184 (32%), Positives = 76/184 (41%), Gaps = 12/184 (6%)
Query: 456 KRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEK 515
K KE+ + R S S S G+ SS+ S + S SSR+ S+S S +K
Sbjct: 497 KEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKK 556
Query: 516 RPHSPSRSPSPKKPLSRDKDGEGRARHSEAEAT---RARRRSRSYSPIR-KRRRDSPSFM 571
R HS SRSP+ K SR + R + A R RRRS S R +RR SPS
Sbjct: 557 R-HSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPS-- 613
Query: 572 EPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRT 631
RR + +R R R S S S D R G+SH R +
Sbjct: 614 RERRRSRSRSRDRRTNRASRSR-----SRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKE 668
Query: 632 RSPS 635
RS S
Sbjct: 669 RSRS 672
Score = 50.8 bits (120), Expect = 4e-06
Identities = 69/272 (25%), Positives = 102/272 (37%), Gaps = 6/272 (2%)
Query: 385 RRRRRRRRRRRSRS-SASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGP 443
+ + + ++ RSRS S+S+ R SS S S + SS + S +P
Sbjct: 497 KEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKK 556
Query: 444 EPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSR 503
R +R++ R R S R ++S RS S R
Sbjct: 557 RHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRER 616
Query: 504 SPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEA---TRARRRSRSYSPI 560
S+SRSR S SRS +K + + G + + EA R + RSRS
Sbjct: 617 RRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKD 676
Query: 561 RKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSY 620
RK ++D E + +KR ++ S S S R+ SRS S +
Sbjct: 677 RK-KKDKEREREQDKRKEKQKREEKDFKFS-SQDDRLKRKRESERTFSRSGSISVKIIRH 734
Query: 621 SSRSHGTRSRTRSPSRTPSPSYHSRSSSESGG 652
SR +S T+ + RSSSES G
Sbjct: 735 DSRQDSKKSTTKDSKKHSGSDSSGRSSSESPG 766
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.124 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,339,481
Number of Sequences: 37866
Number of extensions: 2610988
Number of successful extensions: 57451
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 903
Number of HSP's successfully gapped in prelim test: 3108
Number of HSP's that attempted gapping in prelim test: 19696
Number of HSP's gapped (non-prelim): 20452
length of query: 653
length of database: 18,247,518
effective HSP length: 109
effective length of query: 544
effective length of database: 14,120,124
effective search space: 7681347456
effective search space used: 7681347456
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.