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Search of human proteins with 157502169
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157502169 astacin-like metalloendopeptidase [Homo sapiens]
(431 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157502169 astacin-like metalloendopeptidase [Homo sapiens] 881 0.0
gi|153070264 meprin A beta [Homo sapiens] 140 3e-33
gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom... 129 4e-30
gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom... 129 4e-30
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom... 129 4e-30
gi|6912724 tolloid-like 2 [Homo sapiens] 129 5e-30
gi|22547221 tolloid-like 1 [Homo sapiens] 126 3e-29
gi|153070262 meprin A alpha [Homo sapiens] 122 5e-28
gi|27502386 nuclear factor of activated T-cells, cytosolic compo... 44 4e-04
gi|19923350 nuclear factor of activated T-cells, cytosolic compo... 44 4e-04
gi|27502393 nuclear factor of activated T-cells, cytosolic compo... 44 4e-04
gi|27502391 nuclear factor of activated T-cells, cytosolic compo... 44 4e-04
gi|78499633 phospholipase C, eta 2 [Homo sapiens] 43 6e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni... 42 0.001
gi|19924099 synapsin I isoform Ia [Homo sapiens] 42 0.001
gi|19924097 synapsin I isoform Ib [Homo sapiens] 42 0.001
gi|116256363 transmembrane protease, serine 13 [Homo sapiens] 42 0.001
gi|38683860 insulin receptor substrate 2 [Homo sapiens] 41 0.002
gi|194578898 hypothetical protein LOC100170841 [Homo sapiens] 41 0.002
gi|223972704 hypothetical protein LOC284418 [Homo sapiens] 41 0.002
gi|157739864 ubiquitination factor E4B isoform 1 [Homo sapiens] 41 0.002
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] 40 0.003
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 40 0.004
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 40 0.004
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 39 0.007
gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 39 0.007
gi|22094987 raptor isoform 1 [Homo sapiens] 39 0.007
gi|251823858 raptor isoform 2 [Homo sapiens] 39 0.007
gi|115430223 galectin 3 [Homo sapiens] 39 0.007
gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo sapi... 39 0.007
>gi|157502169 astacin-like metalloendopeptidase [Homo sapiens]
Length = 431
Score = 881 bits (2276), Expect = 0.0
Identities = 431/431 (100%), Positives = 431/431 (100%)
Query: 1 MEGVGGLWPWVLGLLSLPGVILGAPLASSCAGACGTSFPDGLTPEGTQASGDKDIPAINQ 60
MEGVGGLWPWVLGLLSLPGVILGAPLASSCAGACGTSFPDGLTPEGTQASGDKDIPAINQ
Sbjct: 1 MEGVGGLWPWVLGLLSLPGVILGAPLASSCAGACGTSFPDGLTPEGTQASGDKDIPAINQ 60
Query: 61 GLILEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEPSRQVI 120
GLILEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEPSRQVI
Sbjct: 61 GLILEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEPSRQVI 120
Query: 121 LEALAEFERSTCIRFVTYQDQRDFISIIPMYGCFSSVGRSGGMQVVSLAPTCLQKGRGIV 180
LEALAEFERSTCIRFVTYQDQRDFISIIPMYGCFSSVGRSGGMQVVSLAPTCLQKGRGIV
Sbjct: 121 LEALAEFERSTCIRFVTYQDQRDFISIIPMYGCFSSVGRSGGMQVVSLAPTCLQKGRGIV 180
Query: 181 LHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSQSSNMLTPYDYSSVMHYGR 240
LHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSQSSNMLTPYDYSSVMHYGR
Sbjct: 181 LHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSQSSNMLTPYDYSSVMHYGR 240
Query: 241 LAFSRRGLPTITPLWAPSVHIGQRWNLSASDITRVLKLYGCSPSGPRPRGRGSHAHSTGR 300
LAFSRRGLPTITPLWAPSVHIGQRWNLSASDITRVLKLYGCSPSGPRPRGRGSHAHSTGR
Sbjct: 241 LAFSRRGLPTITPLWAPSVHIGQRWNLSASDITRVLKLYGCSPSGPRPRGRGSHAHSTGR 300
Query: 301 SPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLSAEASA 360
SPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLSAEASA
Sbjct: 301 SPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLSAEASA 360
Query: 361 RQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSSEAGIQPVPVQGSPALPGGCV 420
RQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSSEAGIQPVPVQGSPALPGGCV
Sbjct: 361 RQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSSEAGIQPVPVQGSPALPGGCV 420
Query: 421 PRNHFKGMSED 431
PRNHFKGMSED
Sbjct: 421 PRNHFKGMSED 431
>gi|153070264 meprin A beta [Homo sapiens]
Length = 701
Score = 140 bits (352), Expect = 3e-33
Identities = 94/251 (37%), Positives = 131/251 (52%), Gaps = 24/251 (9%)
Query: 43 TPEGTQASG--DKDIPAINQGLILEETPESSFLIEGDII--RPSPFRLLSATSNKWPMGG 98
TPE G D+DI IN+GL L+ L EGDI R + +WP
Sbjct: 23 TPENFDVDGGMDQDIFDINEGLGLD-------LFEGDIRLDRAQIRNSIIGEKYRWPH-- 73
Query: 99 SGVVEVPFLLSSKYDEPSRQVILEALAEFERSTCIRFVTYQDQRDFISIIPMYGCFSSVG 158
+P++L + ++ VIL A + TCI F + + ++IS+ GC+SSVG
Sbjct: 74 ----TIPYVLEDSLEMNAKGVILNAFERYRLKTCIDFKPWAGETNYISVFKGSGCWSSVG 129
Query: 159 -RSGGMQVVSLAPTCLQKGRGIVLHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEIN 217
R G Q +S+ C + V HE +H LGFWHE +R+DRD Y+R+ W+ IL G E N
Sbjct: 130 NRRVGKQELSIGANCDRIAT--VQHEFLHALGFWHEQSRSDRDDYVRIMWDRILSGREHN 187
Query: 218 F---IKSQSSNMLTPYDYSSVMHYGRLAFSRRGLPTI-TPLWAPSVHIGQRWNLSASDIT 273
F S ++ PYDY+SVMHY + AF PTI T + IGQR + S SD+
Sbjct: 188 FNTYSDDISDSLNVPYDYTSVMHYSKTAFQNGTEPTIVTRISDFEDVIGQRMDFSDSDLL 247
Query: 274 RVLKLYGCSPS 284
++ +LY CS S
Sbjct: 248 KLNQLYNCSSS 258
>gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo
sapiens]
Length = 730
Score = 129 bits (325), Expect = 4e-30
Identities = 84/229 (36%), Positives = 113/229 (49%), Gaps = 29/229 (12%)
Query: 94 WPMGGSGVVEVPFLLSSKYDEPSRQVILEALAEFERSTCIRFVTYQDQRDFISIIPM-YG 152
WP G +PF++ + R V +A+ +E+ TC+ F+ D+ +I G
Sbjct: 130 WPDG-----VIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCG 184
Query: 153 CFSSVGR-SGGMQVVSLAPTCLQKGRGIVLHELMHVLGFWHEHTRADRDRYIRVNWNEIL 211
C S VGR GG Q +S+ C + G IV+HEL HV+GFWHEHTR DRDR++ + I
Sbjct: 185 CCSYVGRRGGGPQAISIGKNCDKFG--IVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQ 242
Query: 212 PGFEINFIKSQSSNMLT---PYDYSSVMHYGRLAFSRR-GLPTITPLW---APSVHIGQR 264
PG E NF+K + + + YD+ S+MHY R FSR L TI P + IGQR
Sbjct: 243 PGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQR 302
Query: 265 WNLSASDITRVLKLYGCSPSGPR-------------PRGRGSHAHSTGR 300
LS DI + KLY C G P G +H H R
Sbjct: 303 TRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWR 351
>gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo
sapiens]
Length = 823
Score = 129 bits (325), Expect = 4e-30
Identities = 84/229 (36%), Positives = 113/229 (49%), Gaps = 29/229 (12%)
Query: 94 WPMGGSGVVEVPFLLSSKYDEPSRQVILEALAEFERSTCIRFVTYQDQRDFISIIPM-YG 152
WP G +PF++ + R V +A+ +E+ TC+ F+ D+ +I G
Sbjct: 130 WPDG-----VIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCG 184
Query: 153 CFSSVGR-SGGMQVVSLAPTCLQKGRGIVLHELMHVLGFWHEHTRADRDRYIRVNWNEIL 211
C S VGR GG Q +S+ C + G IV+HEL HV+GFWHEHTR DRDR++ + I
Sbjct: 185 CCSYVGRRGGGPQAISIGKNCDKFG--IVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQ 242
Query: 212 PGFEINFIKSQSSNMLT---PYDYSSVMHYGRLAFSRR-GLPTITPLW---APSVHIGQR 264
PG E NF+K + + + YD+ S+MHY R FSR L TI P + IGQR
Sbjct: 243 PGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQR 302
Query: 265 WNLSASDITRVLKLYGCSPSGPR-------------PRGRGSHAHSTGR 300
LS DI + KLY C G P G +H H R
Sbjct: 303 TRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWR 351
>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
sapiens]
Length = 986
Score = 129 bits (325), Expect = 4e-30
Identities = 84/229 (36%), Positives = 113/229 (49%), Gaps = 29/229 (12%)
Query: 94 WPMGGSGVVEVPFLLSSKYDEPSRQVILEALAEFERSTCIRFVTYQDQRDFISIIPM-YG 152
WP G +PF++ + R V +A+ +E+ TC+ F+ D+ +I G
Sbjct: 130 WPDG-----VIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCG 184
Query: 153 CFSSVGR-SGGMQVVSLAPTCLQKGRGIVLHELMHVLGFWHEHTRADRDRYIRVNWNEIL 211
C S VGR GG Q +S+ C + G IV+HEL HV+GFWHEHTR DRDR++ + I
Sbjct: 185 CCSYVGRRGGGPQAISIGKNCDKFG--IVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQ 242
Query: 212 PGFEINFIKSQSSNMLT---PYDYSSVMHYGRLAFSRR-GLPTITPLW---APSVHIGQR 264
PG E NF+K + + + YD+ S+MHY R FSR L TI P + IGQR
Sbjct: 243 PGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQR 302
Query: 265 WNLSASDITRVLKLYGCSPSGPR-------------PRGRGSHAHSTGR 300
LS DI + KLY C G P G +H H R
Sbjct: 303 TRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWR 351
>gi|6912724 tolloid-like 2 [Homo sapiens]
Length = 1015
Score = 129 bits (324), Expect = 5e-30
Identities = 80/207 (38%), Positives = 110/207 (53%), Gaps = 16/207 (7%)
Query: 88 SATSNKWPMGGSGVVEVPFLLSSKYDEPSRQVILEALAEFERSTCIRFVTYQDQRDFISI 147
S T WP G +P+++ + R + +A+ +E+ TC+ F+ D+ FI
Sbjct: 153 SRTERIWPGG-----VIPYVIGGNFTGSQRAIFKQAMRHWEKHTCVTFIERTDEESFIVF 207
Query: 148 -IPMYGCFSSVGR-SGGMQVVSLAPTCLQKGRGIVLHELMHVLGFWHEHTRADRDRYIRV 205
GC S VGR GG Q +S+ C + G IV HEL HV+GFWHEHTR DRD+++ +
Sbjct: 208 SYRTCGCCSYVGRRGGGPQAISIGKNCDKFG--IVAHELGHVVGFWHEHTRPDRDQHVTI 265
Query: 206 NWNEILPGFEINFIKSQS---SNMLTPYDYSSVMHYGRLAFSRR-GLPTITPLWAPS--- 258
I PG E NF+K ++ S++ YD+ S+MHY R FSR L TI P +
Sbjct: 266 IRENIQPGQEYNFLKMEAGEVSSLGETYDFDSIMHYARNTFSRGVFLDTILPRQDDNGVR 325
Query: 259 VHIGQRWNLSASDITRVLKLYGCSPSG 285
IGQR LS DI + KLY C G
Sbjct: 326 PTIGQRVRLSQGDIAQARKLYKCPACG 352
>gi|22547221 tolloid-like 1 [Homo sapiens]
Length = 1013
Score = 126 bits (317), Expect = 3e-29
Identities = 81/226 (35%), Positives = 114/226 (50%), Gaps = 16/226 (7%)
Query: 83 PFRLLSATSNKWPMGGSGVVEVPFLLSSKYDEPSRQVILEALAEFERSTCIRFVTYQDQR 142
P S T WP G +P+++ + R + +A+ +E+ TC+ F+ D+
Sbjct: 146 PRAATSRTERIWPGG-----VIPYVIGGNFTGSQRAMFKQAMRHWEKHTCVTFIERSDEE 200
Query: 143 DFISIIPM-YGCFSSVGRSG-GMQVVSLAPTCLQKGRGIVLHELMHVLGFWHEHTRADRD 200
+I GC S VGR G G Q +S+ C + G IV+HEL HV+GFWHEHTR DRD
Sbjct: 201 SYIVFTYRPCGCCSYVGRRGNGPQAISIGKNCDKFG--IVVHELGHVIGFWHEHTRPDRD 258
Query: 201 RYIRVNWNEILPGFEINFIK---SQSSNMLTPYDYSSVMHYGRLAFSR-RGLPTITPLWA 256
++ + I PG E NF+K + +++ YD+ S+MHY R FSR L TI P
Sbjct: 259 NHVTIIRENIQPGQEYNFLKMEPGEVNSLGERYDFDSIMHYARNTFSRGMFLDTILPSRD 318
Query: 257 PS---VHIGQRWNLSASDITRVLKLYGCSPSGPRPRGRGSHAHSTG 299
+ IGQR LS DI + KLY C G + + S G
Sbjct: 319 DNGIRPAIGQRTRLSKGDIAQARKLYRCPACGETLQESNGNLSSPG 364
>gi|153070262 meprin A alpha [Homo sapiens]
Length = 746
Score = 122 bits (307), Expect = 5e-28
Identities = 77/236 (32%), Positives = 121/236 (51%), Gaps = 22/236 (9%)
Query: 53 KDIPAINQGLILEETPESSFLIEGDIIRPSPFRLLSATSNKWPMGGSGVVEVPFLLSSKY 112
KDI IN L+ L +GDI+ L + +W +P++L+
Sbjct: 41 KDISEINLAAGLD-------LFQGDILLQKSRNGLRDPNTRWTF------PIPYILADNL 87
Query: 113 DEPSRQVILEALAEFERSTCIRFVTYQDQRDFISIIPMYGCFSSVGRSGGMQVVSLAPTC 172
++ IL A F +C+ F Y+ + +I GC+S VG Q +S+ C
Sbjct: 88 GLNAKGAILYAFEMFRLKSCVDFKPYEGESSYIIFQQFDGCWSEVGDQHVGQNISIGQGC 147
Query: 173 LQKGRGIVLHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSQSS---NMLTP 229
K I+ HE++H LGF+HE +R DRD Y+ + W++IL G++ NF S ++ TP
Sbjct: 148 AYKA--IIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDDSLITDLNTP 205
Query: 230 YDYSSVMHYGRLAFSRR-GLPTITPLWAPSVH--IGQRWNLSASDITRVLKLYGCS 282
YDY S+MHY +F++ +PTIT P + IGQR + SA D+ R+ ++Y C+
Sbjct: 206 YDYESLMHYQPFSFNKNASVPTITAK-IPEFNSIIGQRLDFSAIDLERLNRMYNCT 260
>gi|27502386 nuclear factor of activated T-cells, cytosolic
component 1 isoform C [Homo sapiens]
Length = 930
Score = 43.5 bits (101), Expect = 4e-04
Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 18/121 (14%)
Query: 297 STGRSPAPASLSLQRL-----------LEALSAESRSPDPSGSSAGGQPVPAGPGESPHG 345
S+ RSP+ A+LSL L +LS+ S + + S + A P SP
Sbjct: 134 SSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSP-- 191
Query: 346 WESPALKKLSAEASARQPQ-----TLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSS 400
W+SP + + + P+ TL SPR P E+SWL S++P P +
Sbjct: 192 WQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCN 251
Query: 401 E 401
+
Sbjct: 252 K 252
>gi|19923350 nuclear factor of activated T-cells, cytosolic
component 1 isoform B [Homo sapiens]
Length = 825
Score = 43.5 bits (101), Expect = 4e-04
Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 18/121 (14%)
Query: 297 STGRSPAPASLSLQRL-----------LEALSAESRSPDPSGSSAGGQPVPAGPGESPHG 345
S+ RSP+ A+LSL L +LS+ S + + S + A P SP
Sbjct: 147 SSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSP-- 204
Query: 346 WESPALKKLSAEASARQPQ-----TLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSS 400
W+SP + + + P+ TL SPR P E+SWL S++P P +
Sbjct: 205 WQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCN 264
Query: 401 E 401
+
Sbjct: 265 K 265
>gi|27502393 nuclear factor of activated T-cells, cytosolic
component 1 isoform A [Homo sapiens]
Length = 716
Score = 43.5 bits (101), Expect = 4e-04
Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 18/121 (14%)
Query: 297 STGRSPAPASLSLQRL-----------LEALSAESRSPDPSGSSAGGQPVPAGPGESPHG 345
S+ RSP+ A+LSL L +LS+ S + + S + A P SP
Sbjct: 147 SSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSP-- 204
Query: 346 WESPALKKLSAEASARQPQ-----TLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSS 400
W+SP + + + P+ TL SPR P E+SWL S++P P +
Sbjct: 205 WQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCN 264
Query: 401 E 401
+
Sbjct: 265 K 265
>gi|27502391 nuclear factor of activated T-cells, cytosolic
component 1 isoform E [Homo sapiens]
Length = 812
Score = 43.5 bits (101), Expect = 4e-04
Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 18/121 (14%)
Query: 297 STGRSPAPASLSLQRL-----------LEALSAESRSPDPSGSSAGGQPVPAGPGESPHG 345
S+ RSP+ A+LSL L +LS+ S + + S + A P SP
Sbjct: 134 SSKRSPSTATLSLPSLEAYRDPSCLSPASSLSSRSCNSEASSYESNYSYPYASPQTSP-- 191
Query: 346 WESPALKKLSAEASARQPQ-----TLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSS 400
W+SP + + + P+ TL SPR P E+SWL S++P P +
Sbjct: 192 WQSPCVSPKTTDPEEGFPRGLGACTLLGSPRHSPSTSPRASVTEESWLGARSSRPASPCN 251
Query: 401 E 401
+
Sbjct: 252 K 252
>gi|78499633 phospholipase C, eta 2 [Homo sapiens]
Length = 1416
Score = 42.7 bits (99), Expect = 6e-04
Identities = 47/172 (27%), Positives = 69/172 (40%), Gaps = 32/172 (18%)
Query: 266 NLSASDIT----RVLKLYGCSPSGPRPRGRGSHAHSTGRSPAPASLSLQRLLEALSAESR 321
+++ SDI+ + L L G GP+P SHA GR PA S+S + L SA ++
Sbjct: 878 HVAVSDISGKVKQALGLKGLFLRGPKPGSLDSHA--AGRPPARPSVSQRILRRTASAPTK 935
Query: 322 SPDP---------------SGSSAGGQPVPAGPGESPHGWESPALKKLSAEASARQPQTL 366
S P VP GPG +P E+PA ++ S R + L
Sbjct: 936 SQKPGRRGFPELVLGTRDTGSKGVADDVVPPGPGPAP---EAPA-QEGPGSGSPRDTRPL 991
Query: 367 ASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSSEAGIQPVPVQGSPALPGG 418
++ P +A+E + G VP+S + QG P P G
Sbjct: 992 STQRPLPPLCSLETIAEEPAPGPGPPPPAAVPTSSS-------QGRPPYPTG 1036
Score = 30.0 bits (66), Expect = 4.2
Identities = 22/70 (31%), Positives = 28/70 (40%), Gaps = 9/70 (12%)
Query: 280 GCSPSGPRPRGRGSHAHSTGRS-----PAPASLSLQRLLEALSAESRSPDPSG----SSA 330
G +P P G GS + R P P SL+ + E + P P+ SS
Sbjct: 969 GPAPEAPAQEGPGSGSPRDTRPLSTQRPLPPLCSLETIAEEPAPGPGPPPPAAVPTSSSQ 1028
Query: 331 GGQPVPAGPG 340
G P P GPG
Sbjct: 1029 GRPPYPTGPG 1038
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 42.0 bits (97), Expect = 0.001
Identities = 44/159 (27%), Positives = 60/159 (37%), Gaps = 21/159 (13%)
Query: 283 PSGPRPRGRGSHAHSTGRSP--APASLSLQRLLEALSAESRSPDPSGSSA------GGQP 334
P+ P P+G + T SP +PA+ + A + P P GS A G
Sbjct: 1000 PATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT-PPSPKGSPAATPLPKGAPT 1058
Query: 335 VPAGPGESPHGWES-PALKKLSAEASARQPQTLASSPRSRP-GAGAPGVAQEQSWLAGVS 392
PA SP G + P+LK +A P P GA P A S G++
Sbjct: 1059 TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLA 1118
Query: 393 TKP----------TVPSSEAGIQPVPVQGSPALPGGCVP 421
T P T PS + G+ P +G+P P P
Sbjct: 1119 TPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1157
Score = 38.1 bits (87), Expect = 0.016
Identities = 42/161 (26%), Positives = 60/161 (37%), Gaps = 20/161 (12%)
Query: 280 GCSPSGPRPRGRGSHAHSTGRSP--APASLSLQRLLEALSAESRSPDPSGSSA-----GG 332
G + P P+G + +T SP +PA+ L + A + P P G A G
Sbjct: 1021 GSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATL-PSPKGGPATPSLKGA 1079
Query: 333 QPVPAGPGESPHGWESPALKKLSAEASARQPQTLASSPRSRPGAGAPGV--AQEQSWLAG 390
PA SP G + K + A P + + P GAP A S G
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGG 1139
Query: 391 VSTKP----------TVPSSEAGIQPVPVQGSPALPGGCVP 421
++T P T PS + G+ P +G+P P P
Sbjct: 1140 LATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1180
Score = 35.4 bits (80), Expect = 0.10
Identities = 40/148 (27%), Positives = 53/148 (35%), Gaps = 14/148 (9%)
Query: 282 SPSG----PRPRGRGSHAHSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSA-----GG 332
SP G P P+G + +T SP + + + P P G A G
Sbjct: 1181 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA 1240
Query: 333 QPVPAGPGESPHGWESPALKKLSAEASARQPQTLASSPRSRPGAGA--PGVAQEQSWLAG 390
PA SP G + K + A P +L + P GA P V S G
Sbjct: 1241 PTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG 1300
Query: 391 VSTKPT--VPSSEAGIQPVPVQGSPALP 416
+T P P+ A P P +GSP P
Sbjct: 1301 PATSPPKGAPTPPAATPPSP-KGSPGTP 1327
Score = 33.1 bits (74), Expect = 0.50
Identities = 36/144 (25%), Positives = 52/144 (36%), Gaps = 10/144 (6%)
Query: 282 SPSG----PRPRGRGSHAHSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPA 337
SP G P P+G + +T SP + + + P P G A P P
Sbjct: 1135 SPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA--TPSPK 1192
Query: 338 GPGESPHGWESPALKKLSAEASARQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTV 397
G +P L+ + P T A++P S G G+A A + T
Sbjct: 1193 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG----GLATPSPKGAPTTPAATP 1248
Query: 398 PSSEAGIQPVPVQGSPALPGGCVP 421
PS + G P +G+P P P
Sbjct: 1249 PSPKGGPATPPPKGAPTPPAATPP 1272
Score = 30.4 bits (67), Expect = 3.2
Identities = 46/177 (25%), Positives = 63/177 (35%), Gaps = 18/177 (10%)
Query: 244 SRRGLPT---ITPLWAPSVHIGQRWNLSASDITRVLKLYGCSPSGPRPRGRGSHAHSTGR 300
S +G PT +TPL V + + + S + G P+ P P+ + T
Sbjct: 860 SPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEG--PATPAPK-QAPALSMTSS 916
Query: 301 SPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLSAEASA 360
SP A R A SP P G+ PA SP G + K + A
Sbjct: 917 SPKKA-----RATPAPKGIPASPSPKGAPTP----PAATPPSPKGGPATPSPKWAPTPPA 967
Query: 361 RQPQTLASSPR--SRPGAGAPGVAQEQSWLAGVST-KPTVPSSEAGIQPVPVQGSPA 414
P + P S GA P A S G +T P + + P +GSPA
Sbjct: 968 ATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA 1024
Score = 29.6 bits (65), Expect = 5.5
Identities = 42/184 (22%), Positives = 62/184 (33%), Gaps = 22/184 (11%)
Query: 247 GLPTITPLWAPSVHIGQRWNLSASDITRVLKLYGCSPSGPRPRGRGSHAHSTGR-SPAPA 305
GL T +P AP+ + T K +P+ P +G A + +P P
Sbjct: 1208 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPP 1267
Query: 306 SLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLSAEASARQPQT 365
+ + L L+ P+ + GP SP K + A P +
Sbjct: 1268 AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP--------PKGAPTPPAATPPS 1319
Query: 366 LASSPRSRPGAGAP-----------GVAQEQSWLAGVSTKPTVPSSEAGIQPVPVQGSPA 414
SP + P GAP G + PT PSS+ G P P +P+
Sbjct: 1320 PKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEG--PTPPAATPS 1377
Query: 415 LPGG 418
GG
Sbjct: 1378 HKGG 1381
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 41.6 bits (96), Expect = 0.001
Identities = 44/141 (31%), Positives = 57/141 (40%), Gaps = 22/141 (15%)
Query: 286 PRPRGRGSHAHSTGRSPAPASLSLQRLLEALSAESR-----SPDPSGSSAGGQPVPAGPG 340
P P+G+ H +G P S QRL SA + +P G +PV GPG
Sbjct: 485 PPPQGQ---QHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPG 541
Query: 341 ESPHGWESPALKKLSAEASARQP--QTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVP 398
+P PA +A Q QT S P +GAP Q++ G KP P
Sbjct: 542 -APPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQ---GPPQKPPGP 597
Query: 399 ------SSEAGIQPVPVQGSP 413
+S+AG PVP G P
Sbjct: 598 AGPTRQASQAG--PVPRTGPP 616
Score = 37.4 bits (85), Expect = 0.027
Identities = 50/169 (29%), Positives = 66/169 (39%), Gaps = 53/169 (31%)
Query: 290 GRGSHAHSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSA-------GGQPVPAGPGES 342
GRGSH ++P+P +L L R S P+G A GG P P GPG
Sbjct: 429 GRGSHG----QTPSPGALPLGR--------QTSQQPAGPPAQQRPPPQGGPPQP-GPGPQ 475
Query: 343 -----------PHGWE----------SPALKKLSAEASA-RQPQTLASSP------RSRP 374
P G + SP ++L + SA +QP + A+ P +SRP
Sbjct: 476 RQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRP 535
Query: 375 GAGAPGVAQEQSWLAGVSTKPTVPSSEAGIQ-----PVPVQGSPALPGG 418
AG PG A S + +A Q P P + S A PGG
Sbjct: 536 VAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGG 584
Score = 30.0 bits (66), Expect = 4.2
Identities = 16/47 (34%), Positives = 22/47 (46%)
Query: 286 PRPRGRGSHAHSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSAGG 332
P+P AHS G +P P + + +R A S + GSS GG
Sbjct: 28 PQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGG 74
>gi|19924097 synapsin I isoform Ib [Homo sapiens]
Length = 669
Score = 41.6 bits (96), Expect = 0.001
Identities = 44/141 (31%), Positives = 57/141 (40%), Gaps = 22/141 (15%)
Query: 286 PRPRGRGSHAHSTGRSPAPASLSLQRLLEALSAESR-----SPDPSGSSAGGQPVPAGPG 340
P P+G+ H +G P S QRL SA + +P G +PV GPG
Sbjct: 485 PPPQGQ---QHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPG 541
Query: 341 ESPHGWESPALKKLSAEASARQP--QTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVP 398
+P PA +A Q QT S P +GAP Q++ G KP P
Sbjct: 542 -APPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQ---GPPQKPPGP 597
Query: 399 ------SSEAGIQPVPVQGSP 413
+S+AG PVP G P
Sbjct: 598 AGPTRQASQAG--PVPRTGPP 616
Score = 37.4 bits (85), Expect = 0.027
Identities = 50/169 (29%), Positives = 66/169 (39%), Gaps = 53/169 (31%)
Query: 290 GRGSHAHSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSA-------GGQPVPAGPGES 342
GRGSH ++P+P +L L R S P+G A GG P P GPG
Sbjct: 429 GRGSHG----QTPSPGALPLGR--------QTSQQPAGPPAQQRPPPQGGPPQP-GPGPQ 475
Query: 343 -----------PHGWE----------SPALKKLSAEASA-RQPQTLASSP------RSRP 374
P G + SP ++L + SA +QP + A+ P +SRP
Sbjct: 476 RQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRP 535
Query: 375 GAGAPGVAQEQSWLAGVSTKPTVPSSEAGIQ-----PVPVQGSPALPGG 418
AG PG A S + +A Q P P + S A PGG
Sbjct: 536 VAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGG 584
Score = 30.0 bits (66), Expect = 4.2
Identities = 16/47 (34%), Positives = 22/47 (46%)
Query: 286 PRPRGRGSHAHSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSAGG 332
P+P AHS G +P P + + +R A S + GSS GG
Sbjct: 28 PQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGG 74
>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
Length = 567
Score = 41.6 bits (96), Expect = 0.001
Identities = 41/137 (29%), Positives = 58/137 (42%), Gaps = 28/137 (20%)
Query: 282 SPSGPRPRGRGSHAHSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGE 341
SP+G P GR S A ++ +PA R A ++ + +P S P A P +
Sbjct: 25 SPAGTPP-GRASPAQASPAQASPAGTPPGRASPAQASPAGTPPGRASPGRASPAQASPAQ 83
Query: 342 SPHGWESPALKKLSAEASARQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPT----V 397
+ SPAL LS +S R +SS RS A V+T PT V
Sbjct: 84 ASPARASPALASLSRSSSGR-----SSSARS----------------ASVTTSPTRVYLV 122
Query: 398 PSSEAGIQPVPVQGSPA 414
++ G VP++ SPA
Sbjct: 123 RATPVG--AVPIRSSPA 137
Score = 37.0 bits (84), Expect = 0.035
Identities = 27/87 (31%), Positives = 35/87 (40%), Gaps = 9/87 (10%)
Query: 329 SAGGQPVPAGPGESPHGWESPALKKLSAEASARQPQTLASSPRSRPGAGAPGVAQEQSWL 388
SAG P A P +P G SPA + + A P AS ++ P PG A
Sbjct: 16 SAGASPAQASPAGTPPGRASPAQASPAQASPAGTPPGRASPAQASPAGTPPGRA------ 69
Query: 389 AGVSTKPTVPSSEAGIQPVPVQGSPAL 415
S P+ + Q P + SPAL
Sbjct: 70 ---SPGRASPAQASPAQASPARASPAL 93
Score = 33.5 bits (75), Expect = 0.38
Identities = 37/130 (28%), Positives = 47/130 (36%), Gaps = 19/130 (14%)
Query: 297 STGRSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLSA 356
S G SPA AS + +P S A P A P +P G SPA +
Sbjct: 16 SAGASPAQAS------------PAGTPPGRASPAQASPAQASPAGTPPGRASPAQASPAG 63
Query: 357 EASARQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSSEA-----GIQPVPVQG 411
R AS ++ P +P A+ LA +S + SS A P V
Sbjct: 64 TPPGRASPGRASPAQASPAQASP--ARASPALASLSRSSSGRSSSARSASVTTSPTRVYL 121
Query: 412 SPALPGGCVP 421
A P G VP
Sbjct: 122 VRATPVGAVP 131
>gi|38683860 insulin receptor substrate 2 [Homo sapiens]
Length = 1338
Score = 41.2 bits (95), Expect = 0.002
Identities = 40/136 (29%), Positives = 55/136 (40%), Gaps = 11/136 (8%)
Query: 283 PSGPRPRGRGSHAHSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGES 342
PSG RP G GR+ P LSL+ L +L + P P + G+ + GE
Sbjct: 872 PSGGRPEG---FLGQRGRAVRPTRLSLEGL-PSLPSMHEYPLPPEPKSPGEYINIDFGE- 926
Query: 343 PHGWESPALKKLSAEASARQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSSEA 402
P SP L A A++ ASSP S G+G PG + + + +S + S
Sbjct: 927 PGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSS- 985
Query: 403 GIQPVPVQGSPALPGG 418
P P P G
Sbjct: 986 -----PKSPKPGAPSG 996
>gi|194578898 hypothetical protein LOC100170841 [Homo sapiens]
Length = 379
Score = 41.2 bits (95), Expect = 0.002
Identities = 32/103 (31%), Positives = 39/103 (37%), Gaps = 5/103 (4%)
Query: 280 GCSPSGPRPRGRGSHAHSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGP 339
G P+ P PR + S PAP L QR A + S P AG PAGP
Sbjct: 138 GRCPAPPHPRESTTSFASAPPRPAPG-LEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGP 196
Query: 340 GESPHGWESPALKKLSAEASARQPQTLASSPRSRPGAGAPGVA 382
G +P P L AE P +P + P +P A
Sbjct: 197 GTAPR----PFLPGQPAEVDGNPPPAAPEAPAASPSTASPAPA 235
>gi|223972704 hypothetical protein LOC284418 [Homo sapiens]
Length = 922
Score = 40.8 bits (94), Expect = 0.002
Identities = 31/120 (25%), Positives = 47/120 (39%), Gaps = 2/120 (1%)
Query: 297 STGRSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALKKLSA 356
++G +P P + L ++ P GS G P P ++P G +
Sbjct: 359 ASGLAPYPPAACLSTPYSSIPRGREKAGPMGSHQGPGPPPCQ--KAPSGLVTSCKAPFLV 416
Query: 357 EASARQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSSEAGIQPVPVQGSPALP 416
+ S + P ASS + PG P A S + PS +A P P Q +PA+P
Sbjct: 417 DQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIP 476
Score = 28.9 bits (63), Expect = 9.4
Identities = 34/132 (25%), Positives = 51/132 (38%), Gaps = 20/132 (15%)
Query: 303 APASLSLQRLLEALSAESRSPDPS--------GSSAGGQPVPAGPGESPHG-------WE 347
AP + + L A+ A S P P +SA + PA P S +
Sbjct: 412 APFLVDQSQKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQK 471
Query: 348 SPALKKLSAEASARQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTK---PTVPSSEAGI 404
+PA+ S +ASA +S P P +Q+ + + K PT P ++ +
Sbjct: 472 APAIPAPSRKASAASASPRKASAVPAPPQKTPPPSQKAPSVPTIPQKAVSPTAPKKKSLL 531
Query: 405 QPVPVQGSPALP 416
P P Q ALP
Sbjct: 532 LPAPSQ--KALP 541
>gi|157739864 ubiquitination factor E4B isoform 1 [Homo sapiens]
Length = 1302
Score = 40.8 bits (94), Expect = 0.002
Identities = 44/166 (26%), Positives = 64/166 (38%), Gaps = 5/166 (3%)
Query: 217 NFIKSQSSNMLTPYDYSSVMHYGRLAFSR--RGLPTITPLWAPSVHIGQRWNLSASDITR 274
N + + SN T + SV +G + S P TP + SV + S S
Sbjct: 242 NLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAAS 301
Query: 275 VLKLYGCSPSGPRPRGRGSHAHSTGRSPA--PASLSLQRLLEALSAESRSPDPSGSSAGG 332
L + +P P G+ A S SP P +++ +S S SP P ++
Sbjct: 302 QLAVPS-TPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSP 360
Query: 333 QPVPAGPGESPHGWESPALKKLSAEASARQPQTLASSPRSRPGAGA 378
Q VPA P L S A++R+P +L SP GA
Sbjct: 361 QAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPSLGASGGA 406
>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
Length = 1303
Score = 40.4 bits (93), Expect = 0.003
Identities = 38/132 (28%), Positives = 57/132 (43%), Gaps = 23/132 (17%)
Query: 296 HSTGRSPAPASL---SLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGESPHGWESPALK 352
++TG S AP S S R+ +A + R P+ S+A + GP E+P SP+
Sbjct: 1054 NATGSSAAPGSSDKPSDPRVRKA-PTDPRLQKPTDSTASSRAAKPGPAEAPSPTASPS-- 1110
Query: 353 KLSAEASARQPQTLASSPR--SRPGAGAPGVAQEQSWLAGVST----------KPTVPSS 400
A P T PR + G G G + S L+G+S K T P++
Sbjct: 1111 -----GDASPPATAPYDPRVLAAGGLGQGGGGGQSSVLSGISLYDPRTPNAGGKATEPAA 1165
Query: 401 EAGIQPVPVQGS 412
+ G QP +G+
Sbjct: 1166 DTGAQPKGAEGN 1177
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 40.0 bits (92), Expect = 0.004
Identities = 39/125 (31%), Positives = 51/125 (40%), Gaps = 19/125 (15%)
Query: 299 GRSPAPASLSLQRLLEALSAESRSPDPSGSSAGG--QPVPAGPGESPHGWESPALKKLSA 356
G PA A RLL +E SP+ + AGG +P+P P SP + S
Sbjct: 572 GEGPATAG---PRLLTFQGSEL-SPELQAAMAGGGPEPLPLPPARSP--------SQESI 619
Query: 357 EASARQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSSEAGIQPVPV-----QG 411
A +R P +P G P QE++ G P + SS G P P QG
Sbjct: 620 GARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQG 679
Query: 412 SPALP 416
SP+ P
Sbjct: 680 SPSSP 684
Score = 34.7 bits (78), Expect = 0.17
Identities = 49/180 (27%), Positives = 67/180 (37%), Gaps = 33/180 (18%)
Query: 239 GRLAFSRRGLPTITPLWAPSVHIGQRWNLSASDITRVLKLYGCSPSGPRPRGRGSHAHST 298
G L +R P P V G +NL+ SD + RP+ R
Sbjct: 874 GNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVK-----------RRPKCRE------ 916
Query: 299 GRSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAG-PGESPHGWESPALKKLSAE 357
R P LQ L A S +P P+ P+P+ PGESP P + S
Sbjct: 917 -REP------LQTALLAFGVASATPGPAA------PLPSPTPGESPPASSLPQPEPSSLP 963
Query: 358 ASARQPQTLASSPRSRPGA-GAPGVAQEQSWLAGVSTKPTVPSSEAGIQPVPVQGSPALP 416
A P LA SP +P PG E S + + + P++ A + VP G+ P
Sbjct: 964 AQG-VPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKP 1022
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 40.0 bits (92), Expect = 0.004
Identities = 39/125 (31%), Positives = 51/125 (40%), Gaps = 19/125 (15%)
Query: 299 GRSPAPASLSLQRLLEALSAESRSPDPSGSSAGG--QPVPAGPGESPHGWESPALKKLSA 356
G PA A RLL +E SP+ + AGG +P+P P SP + S
Sbjct: 654 GEGPATAG---PRLLTFQGSEL-SPELQAAMAGGGPEPLPLPPARSP--------SQESI 701
Query: 357 EASARQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSSEAGIQPVPV-----QG 411
A +R P +P G P QE++ G P + SS G P P QG
Sbjct: 702 GARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQG 761
Query: 412 SPALP 416
SP+ P
Sbjct: 762 SPSSP 766
Score = 34.7 bits (78), Expect = 0.17
Identities = 49/180 (27%), Positives = 67/180 (37%), Gaps = 33/180 (18%)
Query: 239 GRLAFSRRGLPTITPLWAPSVHIGQRWNLSASDITRVLKLYGCSPSGPRPRGRGSHAHST 298
G L +R P P V G +NL+ SD + RP+ R
Sbjct: 956 GNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVK-----------RRPKCRE------ 998
Query: 299 GRSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAG-PGESPHGWESPALKKLSAE 357
R P LQ L A S +P P+ P+P+ PGESP P + S
Sbjct: 999 -REP------LQTALLAFGVASATPGPAA------PLPSPTPGESPPASSLPQPEPSSLP 1045
Query: 358 ASARQPQTLASSPRSRPGA-GAPGVAQEQSWLAGVSTKPTVPSSEAGIQPVPVQGSPALP 416
A P LA SP +P PG E S + + + P++ A + VP G+ P
Sbjct: 1046 AQG-VPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGTAPKP 1104
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 39.3 bits (90), Expect = 0.007
Identities = 38/145 (26%), Positives = 53/145 (36%), Gaps = 27/145 (18%)
Query: 283 PSGPRPRGRGSHAHSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGES 342
P PRP + R P P+ +RSP P+ GG P PG +
Sbjct: 1147 PPPPRPVAPPTRPAPPQRPPPPSG-------------ARSPAPTRKEFGGIGAPPSPGVA 1193
Query: 343 PHGWESPALKKLSAEASARQPQTLASSPRSRPGAGAPGVAQEQSWLAGVST-KPTVPSSE 401
E+P + + R+ S P + G PG AG ST +PT+P
Sbjct: 1194 RREMEAP-----KSPGTTRKDNIGRSQPSPQAGLAGPGP-------AGYSTARPTIP-PR 1240
Query: 402 AGIQPVPVQGSPALPGGCVPRNHFK 426
AG+ P + A G P + K
Sbjct: 1241 AGVISAPQSHARASAGRLTPESQSK 1265
>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
Length = 1350
Score = 39.3 bits (90), Expect = 0.007
Identities = 38/145 (26%), Positives = 53/145 (36%), Gaps = 27/145 (18%)
Query: 283 PSGPRPRGRGSHAHSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVPAGPGES 342
P PRP + R P P+ +RSP P+ GG P PG +
Sbjct: 1147 PPPPRPVAPPTRPAPPQRPPPPSG-------------ARSPAPTRKEFGGIGAPPSPGVA 1193
Query: 343 PHGWESPALKKLSAEASARQPQTLASSPRSRPGAGAPGVAQEQSWLAGVST-KPTVPSSE 401
E+P + + R+ S P + G PG AG ST +PT+P
Sbjct: 1194 RREMEAP-----KSPGTTRKDNIGRSQPSPQAGLAGPGP-------AGYSTARPTIP-PR 1240
Query: 402 AGIQPVPVQGSPALPGGCVPRNHFK 426
AG+ P + A G P + K
Sbjct: 1241 AGVISAPQSHARASAGRLTPESQSK 1265
>gi|22094987 raptor isoform 1 [Homo sapiens]
Length = 1335
Score = 39.3 bits (90), Expect = 0.007
Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Query: 274 RVLKLYGCSPSGPR-PRGRGSHAHSTGRSPAPASLSLQRLLEALSAESRSPD-PSGSSAG 331
RVL + S P P +G H H G SP +S S L ++ + S D PSG
Sbjct: 849 RVLDTSSLTQSAPASPTNKGVHIHQAGGSPPASSTSSSSLTNDVAKQPVSRDLPSGRP-- 906
Query: 332 GQPVPAGPGESPHGWESPALKKL 354
G PAG +PH + P +K+
Sbjct: 907 GTTGPAGAQYTPHSHQFPRTRKM 929
>gi|251823858 raptor isoform 2 [Homo sapiens]
Length = 1177
Score = 39.3 bits (90), Expect = 0.007
Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Query: 274 RVLKLYGCSPSGPR-PRGRGSHAHSTGRSPAPASLSLQRLLEALSAESRSPD-PSGSSAG 331
RVL + S P P +G H H G SP +S S L ++ + S D PSG
Sbjct: 691 RVLDTSSLTQSAPASPTNKGVHIHQAGGSPPASSTSSSSLTNDVAKQPVSRDLPSGRP-- 748
Query: 332 GQPVPAGPGESPHGWESPALKKL 354
G PAG +PH + P +K+
Sbjct: 749 GTTGPAGAQYTPHSHQFPRTRKM 771
>gi|115430223 galectin 3 [Homo sapiens]
Length = 250
Score = 39.3 bits (90), Expect = 0.007
Identities = 41/125 (32%), Positives = 49/125 (39%), Gaps = 16/125 (12%)
Query: 312 LLEALSAESRSPDPSG--SSAGGQPVPAG--PGESPHGWESPALKKLSAEASARQPQTLA 367
L +ALS S +P+P G + G QP AG PG S G P A P
Sbjct: 7 LHDALSG-SGNPNPQGWPGAWGNQPAGAGGYPGASYPG-AYPGQAPPGAYPGQAPPGAYP 64
Query: 368 SSPRSRPGAGAPGVAQEQSWLAGVSTKPTVPSSEAGIQPVPVQGSPA----------LPG 417
+P + PGA APGV G PS+ G+PA LPG
Sbjct: 65 GAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPG 124
Query: 418 GCVPR 422
G VPR
Sbjct: 125 GVVPR 129
>gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo
sapiens]
Length = 678
Score = 39.3 bits (90), Expect = 0.007
Identities = 43/161 (26%), Positives = 60/161 (37%), Gaps = 42/161 (26%)
Query: 272 ITRVLKLYGCSPSGPRPRGRGSHAHSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSAG 331
++R+L+ + P+ PR RG A P PA P P+ S
Sbjct: 72 VSRLLERFD-PPAAPRRRGSPERARPPPPPPPPAP--------------PRPPPAAPSPP 116
Query: 332 GQPVPAGPGESPHGWESPALKKLSAEASARQPQTL--------------ASSPRSRPG-- 375
P P G G SP S L+K + + P+ L A PR+ P
Sbjct: 117 AAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANR 176
Query: 376 -AGA-PGVAQEQSWLAGVSTKPTVPSSEAGIQPVPVQGSPA 414
AG+ PG Q W KP V S + + P P G+P+
Sbjct: 177 LAGSPPGSGQ---W------KPKVESGDPSLHPPPSPGTPS 208
Score = 30.8 bits (68), Expect = 2.5
Identities = 35/140 (25%), Positives = 58/140 (41%), Gaps = 10/140 (7%)
Query: 277 KLYGCSPSGPRPRGRGSHAHSTGRSPAPASLSLQRLLEALSAESRSPDPSGSSAGGQPVP 336
K+ PS P G+ + + PA A+ S ++ + A ++ + S + +P P
Sbjct: 190 KVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFEI-------RPAP 242
Query: 337 AGPGESPHGWESPALKKLSAEASARQPQTLASSPRSRPGAGAPGVAQEQSWLAGVSTKPT 396
E+ + A S A++R + P+S+ P ++ L P
Sbjct: 243 KPVMETIPLGDLQARALASLRANSRN--SFMVIPKSKASGAPPPEGRQSVELPKGDLGPA 300
Query: 397 VPSSEAGIQPVP-VQGSPAL 415
PS E G QPVP G+PAL
Sbjct: 301 SPSQELGSQPVPGGDGAPAL 320
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,063,510
Number of Sequences: 37866
Number of extensions: 1154285
Number of successful extensions: 7107
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 602
Number of HSP's that attempted gapping in prelim test: 6177
Number of HSP's gapped (non-prelim): 1457
length of query: 431
length of database: 18,247,518
effective HSP length: 105
effective length of query: 326
effective length of database: 14,271,588
effective search space: 4652537688
effective search space used: 4652537688
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.