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Search of human proteins with 157426866
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157426866 zinc finger, FYVE domain containing 16 [Homo
sapiens]
(1539 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens] 3070 0.0
gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens] 3070 0.0
gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Hom... 714 0.0
gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Hom... 583 e-166
gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo... 135 2e-31
gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens] 86 4e-16
gi|217272865 myotubularin related protein 4 [Homo sapiens] 75 6e-13
gi|194018497 FYVE, RhoGEF and PH domain containing 5 [Homo sapiens] 75 6e-13
gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens] 75 6e-13
gi|4758528 hepatocyte growth factor-regulated tyrosine kinase su... 72 4e-12
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 71 7e-12
gi|198041928 FYVE, RhoGEF and PH domain containing 4 [Homo sapiens] 71 9e-12
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 70 1e-11
gi|13375827 phafin 2 [Homo sapiens] 70 2e-11
gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens] 67 1e-10
gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens] 67 1e-10
gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo sa... 67 1e-10
gi|24797153 faciogenital dysplasia protein [Homo sapiens] 67 1e-10
gi|189217917 FYVE, RhoGEF and PH domain containing 2 [Homo sapiens] 67 1e-10
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 65 5e-10
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 65 5e-10
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 65 5e-10
gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens] 65 7e-10
gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens] 65 7e-10
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 64 1e-09
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 62 4e-09
gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Ho... 62 4e-09
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho... 62 4e-09
gi|153791377 apoptosis-inducing protein D [Homo sapiens] 61 7e-09
gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens] 60 2e-08
>gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 3070 bits (7959), Expect = 0.0
Identities = 1539/1539 (100%), Positives = 1539/1539 (100%)
Query: 1 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 60
MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ
Sbjct: 1 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 60
Query: 61 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 120
ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG
Sbjct: 61 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 120
Query: 121 RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH 180
RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH
Sbjct: 121 RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH 180
Query: 181 DSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV 240
DSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV
Sbjct: 181 DSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV 240
Query: 241 DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS 300
DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS
Sbjct: 241 DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS 300
Query: 301 ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS 360
ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS
Sbjct: 301 ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS 360
Query: 361 SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS 420
SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS
Sbjct: 361 SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS 420
Query: 421 VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES 480
VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES
Sbjct: 421 VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES 480
Query: 481 QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ 540
QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ
Sbjct: 481 QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ 540
Query: 541 YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD 600
YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD
Sbjct: 541 YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD 600
Query: 601 KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR 660
KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR
Sbjct: 601 KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR 660
Query: 661 SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT 720
SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT
Sbjct: 661 SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT 720
Query: 721 ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC 780
ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC
Sbjct: 721 ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC 780
Query: 781 CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT 840
CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT
Sbjct: 781 CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT 840
Query: 841 SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS 900
SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS
Sbjct: 841 SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS 900
Query: 901 PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP 960
PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP
Sbjct: 901 PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP 960
Query: 961 TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED 1020
TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED
Sbjct: 961 TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED 1020
Query: 1021 SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDK 1080
SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDK
Sbjct: 1021 SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDK 1080
Query: 1081 YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT 1140
YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT
Sbjct: 1081 YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT 1140
Query: 1141 ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE 1200
ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE
Sbjct: 1141 ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE 1200
Query: 1201 YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR 1260
YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR
Sbjct: 1201 YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR 1260
Query: 1261 KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF 1320
KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF
Sbjct: 1261 KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF 1320
Query: 1321 VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE 1380
VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE
Sbjct: 1321 VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE 1380
Query: 1381 YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD 1440
YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD
Sbjct: 1381 YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD 1440
Query: 1441 LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP 1500
LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP
Sbjct: 1441 LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP 1500
Query: 1501 QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF 1539
QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF
Sbjct: 1501 QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF 1539
>gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 3070 bits (7959), Expect = 0.0
Identities = 1539/1539 (100%), Positives = 1539/1539 (100%)
Query: 1 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 60
MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ
Sbjct: 1 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 60
Query: 61 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 120
ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG
Sbjct: 61 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 120
Query: 121 RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH 180
RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH
Sbjct: 121 RCSKPICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDH 180
Query: 181 DSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV 240
DSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV
Sbjct: 181 DSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIV 240
Query: 241 DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS 300
DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS
Sbjct: 241 DFNMSSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTS 300
Query: 301 ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS 360
ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS
Sbjct: 301 ALTCSLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDS 360
Query: 361 SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS 420
SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS
Sbjct: 361 SSALHVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNS 420
Query: 421 VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES 480
VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES
Sbjct: 421 VVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVES 480
Query: 481 QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ 540
QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ
Sbjct: 481 QEGLSGTHVPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQ 540
Query: 541 YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD 600
YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD
Sbjct: 541 YLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVD 600
Query: 601 KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR 660
KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR
Sbjct: 601 KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTR 660
Query: 661 SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT 720
SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT
Sbjct: 661 SSKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVT 720
Query: 721 ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC 780
ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC
Sbjct: 721 ANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVC 780
Query: 781 CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT 840
CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT
Sbjct: 781 CNRKCKLQYLEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQT 840
Query: 841 SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS 900
SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS
Sbjct: 841 SSIPSPATLPVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFS 900
Query: 901 PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP 960
PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP
Sbjct: 901 PLSPDVPMTVNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLP 960
Query: 961 TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED 1020
TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED
Sbjct: 961 TSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYRLLCDINKYVCNKISLLPNDED 1020
Query: 1021 SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDK 1080
SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDK
Sbjct: 1021 SLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDK 1080
Query: 1081 YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT 1140
YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT
Sbjct: 1081 YWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFT 1140
Query: 1141 ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE 1200
ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE
Sbjct: 1141 ESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAE 1200
Query: 1201 YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR 1260
YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR
Sbjct: 1201 YKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPR 1260
Query: 1261 KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF 1320
KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF
Sbjct: 1261 KKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCIQNDGIYETQANSATGHPRKVTGASF 1320
Query: 1321 VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE 1380
VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE
Sbjct: 1321 VVFNGALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLRE 1380
Query: 1381 YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD 1440
YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD
Sbjct: 1381 YVDICWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQD 1440
Query: 1441 LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP 1500
LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP
Sbjct: 1441 LSILSTSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLP 1500
Query: 1501 QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF 1539
QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF
Sbjct: 1501 QHYLNDLDSALIPVIHGGTSNSSLPLEIELVFFIIEHLF 1539
>gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Homo
sapiens]
Length = 1425
Score = 714 bits (1842), Expect = 0.0
Identities = 538/1598 (33%), Positives = 799/1598 (50%), Gaps = 234/1598 (14%)
Query: 1 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 60
M++YF+A +LDK+LD+FEQN DE +VSS L ++ +L
Sbjct: 1 MENYFQAEAYNLDKVLDEFEQNEDE----------------TVSSTLLDTKWNKILDPP- 43
Query: 61 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 120
S S+ +S+NE + S +++ + L S T +E
Sbjct: 44 -------SHRLSFNPTLASVNESAV----SNESQPQLKVFSLAHSAPLTTEEE------D 86
Query: 121 RCSK-PICDLISDMGNL---VHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTP--- 173
C+ C+L ++ + +A ++ IK+ D + +A + +++ P
Sbjct: 87 HCANGQDCNLNPEIATMWIDENAVAEDQLIKRNYSWDDQCSAVEVGEKKCGNLACLPDEK 146
Query: 174 --CVSSTDHDSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKK 231
V + H+ D R QND+ + +D + +S + N +K
Sbjct: 147 NVLVVAVMHNCDK-RTLQNDLQDCNNYNSQSLMDAFSCSLDNENRQTDQFSFSINESTEK 205
Query: 232 IFNQLESIVDFNMSSALTRQSSKMFH-AKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAA 290
N + + N R + + + D L P LKD G + + ++ IT+
Sbjct: 206 DMNSEKQMDPLNRPKTEGRSVNHLCPTSSDSLASVCSP-SQLKDDGSIGRDPSMSAITSL 264
Query: 291 ---ECLKEEGKTSALTCSLPKN----EDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQ 343
+ +G +N EDL S+ R + FS + ++K+
Sbjct: 265 TVDSVISSQGTDGCPAVKKQENYIPDEDLTGKISSPRTDLGSPNSFSHMSEGILMKKEPA 324
Query: 344 EDSKSLDLKDNDVIQDSSSALHVSSK-DVPSSLSCLPASGSMCGSLIESKARGDFLPQHE 402
E+S + + S L + K D+P+ L+ ++ R D +E
Sbjct: 325 EESTTEE--------SLRSGLPLLLKPDMPNGSGRNNDCERCSDCLVPNEVRADENEGYE 376
Query: 403 HKDNIQDAVTIHEEIQNSVVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQT- 461
H++ + E N E F E+ + K + M D +++ ++
Sbjct: 377 HEETLGTT-----EFLNMT----EHFSESQDMTNWKLTKL------NEMNDSQVNEEKEK 421
Query: 462 ---VIRAESLDGGDTSSTVVESQEGLS--GTHVPESSDC-CEGFINTFSSNDMDGQDLDY 515
+ + E +G V + GL GT + ES +C I+T ++N + Y
Sbjct: 422 FLQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDSY 481
Query: 516 FNIDEGAKSGPLISDAELDAFLTEQYLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNIN 575
D G P ++ D+ +TE E+ + +SKS+ +
Sbjct: 482 GMQDPGVSFVPKTLPSKEDS-VTE-----------EKEIEESKSEC------------YS 517
Query: 576 NIYFNAEAGAIGESHGINIICETVD--KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQ 633
NIY E G+ ++ T D K+N + N S +P G + K
Sbjct: 518 NIY-EQRGNEATEGSGL-LLNSTGDLMKKNYLHNFCS-----QVPSVLGQSSPKV----- 565
Query: 634 LSVSDINSQSV--GGARPKQLFSLPSRT-RSSKDLNKPDVPDTIESEPSTADTVVPITCA 690
V+ + S SV GGARPKQ +L + + D + D P + + ++
Sbjct: 566 --VASLPSISVPFGGARPKQPSNLKLQIPKPLSDHLQNDFPANSGNNTKNKNDILGKAKL 623
Query: 691 IDSTADPQVSFN-SNYIDIESNSEGGSSFVT--------ANEDSVPENTCKEG------- 734
+++A S + N ++++N E S+ A P+N + G
Sbjct: 624 GENSATNVCSPSLGNISNVDTNGEHLESYEAEISTRPCLALAPDSPDNDLRAGQFGISAR 683
Query: 735 ---LVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLE 791
LG+ P WVPDS+APNCM C+ +FTFTKRRHHCRACGKVFC CC+ KCKL Y++
Sbjct: 684 KPFTTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMD 743
Query: 792 -KEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDE-CTTVQPPQENQTSSIPSPATL 849
KEARVCV+C+ + AQA+E MMS + + N+ E C+T+ P Q+ Q S
Sbjct: 744 RKEARVCVICHSVLMNAQAWENMMSASSQSPNPNNPAEYCSTIPPLQQAQASG------- 796
Query: 850 PVSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSEDFSPLSPDVPMT 909
AL P P V +
Sbjct: 797 ---ALSSP---------------------------------------------PPTVMVP 808
Query: 910 VNTVDHSHSTTVEKPNNETGDITRNEIIQSPISQVPSVEKLSMNTGNEGLPTSGSFTLDD 969
V + H V +P + + I+ P +V KL+MN TS + TL
Sbjct: 809 VGVLKHP-GAEVAQPREQRRVWFADGIL--PNGEVADAAKLTMNG------TSSAGTL-- 857
Query: 970 DVFAETEEPSSPTGVLVNSNLPIASISDYRL----LCDINKYVCNKISLLPNDEDSLPPL 1025
A + +P P + P+ + +D L + + V + ++L+P ED LPP+
Sbjct: 858 ---AVSHDPVKPV-----TTSPLPAETDICLFSGSITQVGSPVGSAMNLIP--EDGLPPI 907
Query: 1026 LVASGEKGSVPVVEEHPSHEQIILLLEGEGFHPVTFVLNANLLVNVKFIFYSSDKYWYFS 1085
L+++G KG VEE PS ++ LE G P+ FVLNANLL VK + Y + K W F+
Sbjct: 908 LISTGVKGDY-AVEEKPSQISVMQQLEDGGPDPLVFVLNANLLSMVKIVNYVNRKCWCFT 966
Query: 1086 TNGLHGLGQAEIIILLLCLPNEDTIPKDIFRLFITIYKDALKGKYIENLDNITFTESFLS 1145
T G+H +GQ+EI+ILL CLP+E +PKDIF F+ +Y+DAL G + NL + F++SFL
Sbjct: 967 TKGMHAVGQSEIVILLQCLPDEKCLPKDIFNHFVQLYRDALAGNVVSNLGHSFFSQSFLG 1026
Query: 1146 SKDHGGFLFITPTFQKLDDLSLPSNPFLCGILIQKLEIPWAKVFPMRLMLRLGAEYKAYP 1205
SK+HGGFL++T T+Q L DL LP+ P+L GILIQK E PWAKVFP+RLMLRLGAEY+ YP
Sbjct: 1027 SKEHGGFLYVTSTYQSLQDLVLPTPPYLFGILIQKWETPWAKVFPIRLMLRLGAEYRLYP 1086
Query: 1206 APLTSIRGRKPLFGEIGHTIMNLLVDLRNYQYTLHNIDQLLIHMEMGKSCIKIPRKKYSD 1265
PL S+R RKPLFGE GHTIMNLL D RNYQYTL + L++ ME+ K+ IKIP +Y++
Sbjct: 1087 CPLFSVRFRKPLFGETGHTIMNLLADFRNYQYTLPVVQGLVVDMEVRKTSIKIPSNRYNE 1146
Query: 1266 VMKVLNSSNEHVISIGASFSTEADSHLVCIQN-DGIYETQANSATGHPRKVTGASFVVFN 1324
+MK +N SNEHV++ GA F+ +ADSHLVC+QN DG Y+TQA S PRKVTGASF VF+
Sbjct: 1147 MMKAMNKSNEHVLAGGACFNEKADSHLVCVQNDDGNYQTQAISIHNQPRKVTGASFFVFS 1206
Query: 1325 GALKTSSGFLAKSSIVEDGLMVQITPETMNGLRLALREQKDFKITCGKVDAVDLREYVDI 1384
GALK+SSG+LAKSSIVEDG+MVQIT E M+ LR ALRE KDF ITCGK DA + +E++ I
Sbjct: 1207 GALKSSSGYLAKSSIVEDGVMVQITAENMDSLRQALREMKDFTITCGKADAEEPQEHIHI 1266
Query: 1385 CWVDAEEKGNKGVISSVDGISLQGFPSEKIKLEADFETDEKIVKCTEVFYFLKDQDLSIL 1444
WVD ++ +KGV+S +DG S++ + KI ++++ + K+++ TEVF+ D + L
Sbjct: 1267 QWVDDDKNVSKGVVSPIDGKSMETITNVKIFHGSEYKANGKVIRWTEVFFLENDDQHNCL 1326
Query: 1445 S---TSYQFAKEIAMACSAALCPHLKTLKSNGMNKIGLRVSIDTDMVEFQAGSEGQLLPQ 1501
S + + +A A ALCPHLK LK +GM K+GLRV++D+D V +QAGS GQ LP
Sbjct: 1327 SDPADHSRLTEHVAKAFCLALCPHLKLLKEDGMTKLGLRVTLDSDQVGYQAGSNGQPLPS 1386
Query: 1502 HYLNDLDSALIPVIHGGTSN-SSLPLEIELVFFIIEHL 1538
Y+NDLDSAL+PVIHGG S P+ +EL+F+I+E++
Sbjct: 1387 QYMNDLDSALVPVIHGGACQLSEGPVVMELIFYILENI 1424
>gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Homo
sapiens]
Length = 1366
Score = 583 bits (1504), Expect = e-166
Identities = 311/608 (51%), Positives = 419/608 (68%), Gaps = 28/608 (4%)
Query: 940 PISQVPSVEKLSMNTGNEGLPTSGSFTLDDDVFAETEEPSSPTGVLVNSNLPIASISDYR 999
P +V KL+MN TS + TL A + +P P + P+ + +D
Sbjct: 777 PNGEVADAAKLTMNG------TSSAGTL-----AVSHDPVKPV-----TTSPLPAETDIC 820
Query: 1000 L----LCDINKYVCNKISLLPNDEDSLPPLLVASGEKGSVPVVEEHPSHEQIILLLEGEG 1055
L + + V + ++L+P ED LPP+L+++G KG VEE PS ++ LE G
Sbjct: 821 LFSGSITQVGSPVGSAMNLIP--EDGLPPILISTGVKGDY-AVEEKPSQISVMQQLEDGG 877
Query: 1056 FHPVTFVLNANLLVNVKFIFYSSDKYWYFSTNGLHGLGQAEIIILLLCLPNEDTIPKDIF 1115
P+ FVLNANLL VK + Y + K W F+T G+H +GQ+EI+ILL CLP+E +PKDIF
Sbjct: 878 PDPLVFVLNANLLSMVKIVNYVNRKCWCFTTKGMHAVGQSEIVILLQCLPDEKCLPKDIF 937
Query: 1116 RLFITIYKDALKGKYIENLDNITFTESFLSSKDHGGFLFITPTFQKLDDLSLPSNPFLCG 1175
F+ +Y+DAL G + NL + F++SFL SK+HGGFL++T T+Q L DL LP+ P+L G
Sbjct: 938 NHFVQLYRDALAGNVVSNLGHSFFSQSFLGSKEHGGFLYVTSTYQSLQDLVLPTPPYLFG 997
Query: 1176 ILIQKLEIPWAKVFPMRLMLRLGAEYKAYPAPLTSIRGRKPLFGEIGHTIMNLLVDLRNY 1235
ILIQK E PWAKVFP+RLMLRLGAEY+ YP PL S+R RKPLFGE GHTIMNLL D RNY
Sbjct: 998 ILIQKWETPWAKVFPIRLMLRLGAEYRLYPCPLFSVRFRKPLFGETGHTIMNLLADFRNY 1057
Query: 1236 QYTLHNIDQLLIHMEMGKSCIKIPRKKYSDVMKVLNSSNEHVISIGASFSTEADSHLVCI 1295
QYTL + L++ ME+ K+ IKIP +Y+++MK +N SNEHV++ GA F+ +ADSHLVC+
Sbjct: 1058 QYTLPVVQGLVVDMEVRKTSIKIPSNRYNEMMKAMNKSNEHVLAGGACFNEKADSHLVCV 1117
Query: 1296 QN-DGIYETQANSATGHPRKVTGASFVVFNGALKTSSGFLAKSSIVEDGLMVQITPETMN 1354
QN DG Y+TQA S PRKVTGASF VF+GALK+SSG+LAKSSIVEDG+MVQIT E M+
Sbjct: 1118 QNDDGNYQTQAISIHNQPRKVTGASFFVFSGALKSSSGYLAKSSIVEDGVMVQITAENMD 1177
Query: 1355 GLRLALREQKDFKITCGKVDAVDLREYVDICWVDAEEKGNKGVISSVDGISLQGFPSEKI 1414
LR ALRE KDF ITCGK DA + +E++ I WVD ++ +KGV+S +DG S++ + KI
Sbjct: 1178 SLRQALREMKDFTITCGKADAEEPQEHIHIQWVDDDKNVSKGVVSPIDGKSMETITNVKI 1237
Query: 1415 KLEADFETDEKIVKCTEVFYFLKDQDLSILS---TSYQFAKEIAMACSAALCPHLKTLKS 1471
++++ + K+++ TEVF+ D + LS + + +A A ALCPHLK LK
Sbjct: 1238 FHGSEYKANGKVIRWTEVFFLENDDQHNCLSDPADHSRLTEHVAKAFCLALCPHLKLLKE 1297
Query: 1472 NGMNKIGLRVSIDTDMVEFQAGSEGQLLPQHYLNDLDSALIPVIHGGTSN-SSLPLEIEL 1530
+GM K+GLRV++D+D V +QAGS GQ LP Y+NDLDSAL+PVIHGG S P+ +EL
Sbjct: 1298 DGMTKLGLRVTLDSDQVGYQAGSNGQPLPSQYMNDLDSALVPVIHGGACQLSEGPVVMEL 1357
Query: 1531 VFFIIEHL 1538
+F+I+E++
Sbjct: 1358 IFYILENI 1365
Score = 155 bits (392), Expect = 3e-37
Identities = 232/960 (24%), Positives = 375/960 (39%), Gaps = 209/960 (21%)
Query: 1 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 60
M++YF+A +LDK+LD+FEQN DE +VSS L ++ +L
Sbjct: 1 MENYFQAEAYNLDKVLDEFEQNEDE----------------TVSSTLLDTKWNKILDPP- 43
Query: 61 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 120
S S+ +S+NE + S +++ + L S T +E
Sbjct: 44 -------SHRLSFNPTLASVNESAV----SNESQPQLKVFSLAHSAPLTTEEE------D 86
Query: 121 RCSK-PICDLISDMGNL---VHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTP--- 173
C+ C+L ++ + +A ++ IK+ D + +A + +++ P
Sbjct: 87 HCANGQDCNLNPEIATMWIDENAVAEDQLIKRNYSWDDQCSAVEVGEKKCGNLACLPDEK 146
Query: 174 --CVSSTDHDSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKK 231
V + H+ D R QND+ + +D + +S + N +K
Sbjct: 147 NVLVVAVMHNCDK-RTLQNDLQDCNNYNSQSLMDAFSCSLDNENRQTDQFSFSINESTEK 205
Query: 232 IFNQLESIVDFNMSSALTRQSSKMFH-AKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAA 290
N + + N R + + + D L P LKD G + + ++ IT+
Sbjct: 206 DMNSEKQMDPLNRPKTEGRSVNHLCPTSSDSLASVCSP-SQLKDDGSIGRDPSMSAITSL 264
Query: 291 ---ECLKEEGKTSALTCSLPKN----EDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQ 343
+ +G +N EDL S+ R + FS + ++K+
Sbjct: 265 TVDSVISSQGTDGCPAVKKQENYIPDEDLTGKISSPRTDLGSPNSFSHMSEGILMKKEPA 324
Query: 344 EDSKSLDLKDNDVIQDSSSALHVSSK-DVPSSLSCLPASGSMCGSLIESKARGDFLPQHE 402
E+S + + S L + K D+P+ L+ ++ R D +E
Sbjct: 325 EESTTEE--------SLRSGLPLLLKPDMPNGSGRNNDCERCSDCLVPNEVRADENEGYE 376
Query: 403 HKDNIQDAVTIHEEIQNSVVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQT- 461
H++ + E N E F E+ + K + M D +++ ++
Sbjct: 377 HEETLGTT-----EFLNMT----EHFSESQDMTNWKLTKL------NEMNDSQVNEEKEK 421
Query: 462 ---VIRAESLDGGDTSSTVVESQEGLS--GTHVPESSDC-CEGFINTFSSNDMDGQDLDY 515
+ + E +G V + GL GT + ES +C I+T ++N + Y
Sbjct: 422 FLQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDSY 481
Query: 516 FNIDEGAKSGPLISDAELDAFLTEQYLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNIN 575
D G P ++ D+ +TE E+ + +SKS+ +
Sbjct: 482 GMQDPGVSFVPKTLPSKEDS-VTE-----------EKEIEESKSEC------------YS 517
Query: 576 NIYFNAEAGAIGESHGINIICETVD--KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQ 633
NIY E G+ ++ T D K+N + N S +P G + K
Sbjct: 518 NIY-EQRGNEATEGSGL-LLNSTGDLMKKNYLHNFCS-----QVPSVLGQSSPKV----- 565
Query: 634 LSVSDINSQSV--GGARPKQLFSLPSRT-RSSKDLNKPDVPDTIESEPSTADTVVPITCA 690
V+ + S SV GGARPKQ +L + + D + D P + + ++
Sbjct: 566 --VASLPSISVPFGGARPKQPSNLKLQIPKPLSDHLQNDFPANSGNNTKNKNDILGKAKL 623
Query: 691 IDSTADPQVSFN-SNYIDIESNSEGGSSFVT--------ANEDSVPENTCKEG------- 734
+++A S + N ++++N E S+ A P+N + G
Sbjct: 624 GENSATNVCSPSLGNISNVDTNGEHLESYEAEISTRPCLALAPDSPDNDLRAGQFGISAR 683
Query: 735 ---LVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLE 791
LG+ P WVPDS+APNCM C+ +FTFTKRRHHCRACGKVFC CC+ KCKL Y++
Sbjct: 684 KPFTTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMD 743
Query: 792 -KEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQTSSIPSPATLP 850
KEARVCV+C HS QP
Sbjct: 744 RKEARVCVIC------------------------HSVLMNVAQP---------------- 763
Query: 851 VSALKQPGVEGLCSKEQKRVWFADGILPNGEVADTTKL------SSGSKRCSEDFSPLSP 904
+EQ+RVWFADGILPNGEVAD KL S+G+ S D P+ P
Sbjct: 764 --------------REQRRVWFADGILPNGEVADAAKLTMNGTSSAGTLAVSHD--PVKP 807
>gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo
sapiens]
Length = 762
Score = 135 bits (341), Expect = 2e-31
Identities = 202/854 (23%), Positives = 342/854 (40%), Gaps = 147/854 (17%)
Query: 1 MDSYFKAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQ 60
M++YF+A +LDK+LD+FEQN DE +VSS L ++ +L
Sbjct: 1 MENYFQAEAYNLDKVLDEFEQNEDE----------------TVSSTLLDTKWNKILDPP- 43
Query: 61 ECVNSCASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMG 120
S S+ +S+NE + S +++ + L S T +E
Sbjct: 44 -------SHRLSFNPTLASVNESAV----SNESQPQLKVFSLAHSAPLTTEEE------D 86
Query: 121 RCSK-PICDLISDMGNL---VHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTP--- 173
C+ C+L ++ + +A ++ IK+ D + +A + +++ P
Sbjct: 87 HCANGQDCNLNPEIATMWIDENAVAEDQLIKRNYSWDDQCSAVEVGEKKCGNLACLPDEK 146
Query: 174 --CVSSTDHDSDTVREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKK 231
V + H+ D R QND+ + +D + +S + N +K
Sbjct: 147 NVLVVAVMHNCDK-RTLQNDLQDCNNYNSQSLMDAFSCSLDNENRQTDQFSFSINESTEK 205
Query: 232 IFNQLESIVDFNMSSALTRQSSKMFH-AKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAA 290
N + + N R + + + D L P LKD G + + ++ IT+
Sbjct: 206 DMNSEKQMDPLNRPKTEGRSVNHLCPTSSDSLASVCSP-SQLKDDGSIGRDPSMSAITSL 264
Query: 291 ---ECLKEEGKTSALTCSLPKN----EDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQ 343
+ +G +N EDL S+ R + FS + ++K+
Sbjct: 265 TVDSVISSQGTDGCPAVKKQENYIPDEDLTGKISSPRTDLGSPNSFSHMSEGILMKKEPA 324
Query: 344 EDSKSLDLKDNDVIQDSSSALHVSSK-DVPSSLSCLPASGSMCGSLIESKARGDFLPQHE 402
E+S + + S L + K D+P+ L+ ++ R D +E
Sbjct: 325 EESTTEE--------SLRSGLPLLLKPDMPNGSGRNNDCERCSDCLVPNEVRADENEGYE 376
Query: 403 HKDNIQDAVTIHEEIQNSVVLGGEPFKENDLLKQEKCKSILLQSLIEGMEDRKIDPDQT- 461
H++ + E N E F E+ + K + M D +++ ++
Sbjct: 377 HEETLGTT-----EFLNMT----EHFSESQDMTNWKLTKL------NEMNDSQVNEEKEK 421
Query: 462 ---VIRAESLDGGDTSSTVVESQEGLS--GTHVPESSDC-CEGFINTFSSNDMDGQDLDY 515
+ + E +G V + GL GT + ES +C I+T ++N + Y
Sbjct: 422 FLQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDSY 481
Query: 516 FNIDEGAKSGPLISDAELDAFLTEQYLQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNIN 575
D G P ++ D+ +TE E+ + +SKS+ +
Sbjct: 482 GMQDPGVSFVPKTLPSKEDS-VTE-----------EKEIEESKSEC------------YS 517
Query: 576 NIYFNAEAGAIGESHGINIICETVD--KQNTIENGLSLGEKSTIPVQQGLPTSKSEITNQ 633
NIY E G+ ++ T D K+N + N S +P G + K
Sbjct: 518 NIY-EQRGNEATEGSGL-LLNSTGDLMKKNYLHNFCS-----QVPSVLGQSSPKV----- 565
Query: 634 LSVSDINSQSV--GGARPKQLFSLPSRT-RSSKDLNKPDVPDTIESEPSTADTVVPITCA 690
V+ + S SV GGARPKQ +L + + D + D P + + ++
Sbjct: 566 --VASLPSISVPFGGARPKQPSNLKLQIPKPLSDHLQNDFPANSGNNTKNKNDILGKAKL 623
Query: 691 IDSTADPQVSFN-SNYIDIESNSEGGSSFVT--------ANEDSVPENTCKEG------- 734
+++A S + N ++++N E S+ A P+N + G
Sbjct: 624 GENSATNVCSPSLGNISNVDTNGEHLESYEAEISTRPCLALAPDSPDNDLRAGQFGISAR 683
Query: 735 ---LVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLE 791
LG+ P WVPDS+APNCM C+ +FTFTKRRHHCRACGKVFC CC+ KCKL Y++
Sbjct: 684 KPFTTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMD 743
Query: 792 -KEARVCVVCYETI 804
KEARVCV+C+ +
Sbjct: 744 RKEARVCVICHSVL 757
>gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens]
Length = 1430
Score = 85.5 bits (210), Expect = 4e-16
Identities = 54/154 (35%), Positives = 74/154 (48%), Gaps = 8/154 (5%)
Query: 724 DSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNR 783
D +E LG K P W+PD+ A CM C +FT T RRHHCRACGK+ C C +
Sbjct: 1199 DEADSENKEEVSPLGSKAPIWIPDTRATMCMICTSEFTLTWRRHHCRACGKIVCQACSSN 1258
Query: 784 KCKLQYLEKE-ARVCVVCYETISKA--QAFERMMSPTGSNLKSNHSDECTTVQP-PQENQ 839
K L YL+ + ARVC C++ + K Q R+ SP N KS S + + P +
Sbjct: 1259 KYGLDYLKNQPARVCEHCFQELQKLDHQHSPRIGSP--GNHKSPSSALSSVLHSIPSGRK 1316
Query: 840 TSSIPSPATLPVSALKQPGVEGLC--SKEQKRVW 871
IP+ + + + G SK K+ W
Sbjct: 1317 QKKIPAALKEVSANTEDSSMSGYLYRSKGNKKPW 1350
>gi|217272865 myotubularin related protein 4 [Homo sapiens]
Length = 1195
Score = 74.7 bits (182), Expect = 6e-13
Identities = 42/123 (34%), Positives = 61/123 (49%), Gaps = 4/123 (3%)
Query: 695 ADPQVSFNSNYIDI-ESNSEGGSSFVTANEDSVPENTCKEGLVLGQKQPT-WVPDSEAPN 752
A+P + + ++ + ES+ F + + + E + + + T WVPD A +
Sbjct: 1060 AEPPMDYEDDFTCLKESDGSDTEDFGSDHSEDCLSEASWEPVDKKETEVTRWVPDHMASH 1119
Query: 753 CMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKL--QYLEKEARVCVVCYETISKAQAF 810
C NC +F KRRHHCR CG VFC CC+ K + Q L VC CYE I ++A
Sbjct: 1120 CYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLPIPDQQLYDPVLVCNSCYEHIQVSRAR 1179
Query: 811 ERM 813
E M
Sbjct: 1180 ELM 1182
>gi|194018497 FYVE, RhoGEF and PH domain containing 5 [Homo sapiens]
Length = 1462
Score = 74.7 bits (182), Expect = 6e-13
Identities = 50/154 (32%), Positives = 72/154 (46%), Gaps = 18/154 (11%)
Query: 734 GLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYL-EK 792
G+ LG++ PT VP + CMNC F+ T RRHHC ACGK+ C C K L+YL ++
Sbjct: 1229 GVSLGERPPTLVPVTHVMMCMNCGCDFSLTLRRHHCHACGKIVCRNCSRNKYPLKYLKDR 1288
Query: 793 EARVCVVCYETISK-AQAFERMM------------SPTGSNLKSNHSDECTTVQPPQENQ 839
A+VC C+ + K +A +M SP S S S ++ P +
Sbjct: 1289 MAKVCDGCFGELKKRGRAVPGLMRERPVSMSFPLSSPRFSG--SAFSSVFQSINPSTFKK 1346
Query: 840 TSSIPSPATLPVSALKQPGVEGLCS--KEQKRVW 871
+PS T ++ + + G S K KR W
Sbjct: 1347 QKKVPSALTEVAASGEGSAISGYLSRCKRGKRHW 1380
>gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens]
Length = 234
Score = 74.7 bits (182), Expect = 6e-13
Identities = 35/92 (38%), Positives = 51/92 (55%), Gaps = 4/92 (4%)
Query: 726 VPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKC 785
VPE+ G G ++P WVPD E CM C KF F R+HHCR CGK FC CC++K
Sbjct: 24 VPEHRAF-GSPFGLEEPQWVPDKECRRCMQCDAKFDFLTRKHHCRRCGKCFCDRCCSQKV 82
Query: 786 KLQYL--EKEARVCVVC-YETISKAQAFERMM 814
L+ + R C C ++ +A+ +++ +
Sbjct: 83 PLRRMCFVDPVRQCAECALVSLKEAEFYDKQL 114
>gi|4758528 hepatocyte growth factor-regulated tyrosine kinase
substrate [Homo sapiens]
Length = 777
Score = 72.0 bits (175), Expect = 4e-12
Identities = 42/126 (33%), Positives = 60/126 (47%), Gaps = 21/126 (16%)
Query: 727 PENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCK 786
PE + + ++ P WV +A C C+V+F R+HHCRACG++FCG C ++
Sbjct: 143 PEFKESDAMFAAERAPDWV---DAEECHRCRVQFGVMTRKHHCRACGQIFCGKCSSKYST 199
Query: 787 LQY--LEKEARVCVVCYETISKAQAFERMMSPTGSNLKSNHSDECTTVQPPQENQTSSIP 844
+ +EKE RVC CYE + N K+ TT PP E TS +
Sbjct: 200 IPKFGIEKEVRVCEPCYEQL---------------NRKAEGKATSTTELPP-EYLTSPLS 243
Query: 845 SPATLP 850
+ LP
Sbjct: 244 QQSQLP 249
>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
Length = 2098
Score = 71.2 bits (173), Expect = 7e-12
Identities = 35/100 (35%), Positives = 52/100 (52%), Gaps = 4/100 (4%)
Query: 744 WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKC--KLQYLEKEARVCVVCY 801
W+PDS+ C +C KFT +RRHHCR CG++FC CCN++ K + R C C
Sbjct: 155 WMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYTGDLRACTYC- 213
Query: 802 ETISKAQAFERMMSPTGSNLKSNHSDECT-TVQPPQENQT 840
I+ + A + G +L + C+ +V P E +T
Sbjct: 214 RKIALSYAHSTDSNSIGEDLNALSDSACSVSVLDPSEPRT 253
>gi|198041928 FYVE, RhoGEF and PH domain containing 4 [Homo sapiens]
Length = 766
Score = 70.9 bits (172), Expect = 9e-12
Identities = 33/71 (46%), Positives = 45/71 (63%), Gaps = 2/71 (2%)
Query: 737 LGQKQPTWVPDSEAPNCMNCQVKFT-FTKRRHHCRACGKVFCGVCCNRKCKLQY-LEKEA 794
LG++ P W+ D+E CM C+ F T+RRHHCRACG V C C + K +L+Y K +
Sbjct: 549 LGKRAPRWIRDNEVTMCMKCKEPFNALTRRRHHCRACGYVVCWKCSDYKAQLEYDGGKLS 608
Query: 795 RVCVVCYETIS 805
+VC CY+ IS
Sbjct: 609 KVCKDCYQIIS 619
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapiens]
Length = 1478
Score = 70.5 bits (171), Expect = 1e-11
Identities = 29/91 (31%), Positives = 51/91 (56%), Gaps = 5/91 (5%)
Query: 744 WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLEKEARVCVVCYET 803
W+ D+EA +C++C+ +F++ RRHHCR CG++FC CCN ++ K+ R C C++
Sbjct: 1170 WLGDTEANHCLDCKREFSWMVRRHHCRICGRIFCYYCCNNYVLSKHGGKKERCCRACFQK 1229
Query: 804 ISKAQAFERMMSPTGSNLKSNHSDECTTVQP 834
+S+ SP S ++ + + P
Sbjct: 1230 LSEGPG-----SPDSSGSGTSQGEPSPALSP 1255
>gi|13375827 phafin 2 [Homo sapiens]
Length = 249
Score = 69.7 bits (169), Expect = 2e-11
Identities = 33/64 (51%), Positives = 38/64 (59%), Gaps = 2/64 (3%)
Query: 744 WVPDSEAPNCMNCQ-VKFTFTKRRHHCRACGKVFCGVCCNRKCKL-QYLEKEARVCVVCY 801
WVPDSEA CM CQ KFT RRHHCR CG V CG C ++ L K R+C CY
Sbjct: 149 WVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSKPVRICDFCY 208
Query: 802 ETIS 805
+ +S
Sbjct: 209 DLLS 212
>gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]
Length = 1161
Score = 67.4 bits (163), Expect = 1e-10
Identities = 28/63 (44%), Positives = 37/63 (58%), Gaps = 2/63 (3%)
Query: 744 WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKL--QYLEKEARVCVVCY 801
W+PD A +C C F R+HHCR CG VFC CCN+K + Q L + +RVC CY
Sbjct: 1079 WLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCY 1138
Query: 802 ETI 804
++
Sbjct: 1139 SSL 1141
>gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]
Length = 1198
Score = 67.4 bits (163), Expect = 1e-10
Identities = 28/63 (44%), Positives = 37/63 (58%), Gaps = 2/63 (3%)
Query: 744 WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKL--QYLEKEARVCVVCY 801
W+PD A +C C F R+HHCR CG VFC CCN+K + Q L + +RVC CY
Sbjct: 1116 WLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQQLFEPSRVCKSCY 1175
Query: 802 ETI 804
++
Sbjct: 1176 SSL 1178
>gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo
sapiens]
Length = 641
Score = 67.4 bits (163), Expect = 1e-10
Identities = 30/79 (37%), Positives = 43/79 (54%), Gaps = 7/79 (8%)
Query: 723 EDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCN 782
ED N +GLV W+ D EA +C C+ +F+ +KR+HHCR CG++FC C +
Sbjct: 558 EDIKEANKALQGLV-------WLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSD 610
Query: 783 RKCKLQYLEKEARVCVVCY 801
+ L K RVC C+
Sbjct: 611 NELPLPSSPKPVRVCDSCH 629
>gi|24797153 faciogenital dysplasia protein [Homo sapiens]
Length = 961
Score = 67.0 bits (162), Expect = 1e-10
Identities = 34/82 (41%), Positives = 47/82 (57%), Gaps = 5/82 (6%)
Query: 722 NEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVKF-TFTKRRHHCRACGKVFCGVC 780
+ED+ P + + LG++ PT + + E CM CQ F + TKRRHHC+ACG V CG C
Sbjct: 708 DEDTPPNSP---NVDLGKRAPTPIREKEVTMCMRCQEPFNSITKRRHHCKACGHVVCGKC 764
Query: 781 CNRKCKLQY-LEKEARVCVVCY 801
+ +L Y + RVC CY
Sbjct: 765 SEFRARLVYDNNRSNRVCTDCY 786
>gi|189217917 FYVE, RhoGEF and PH domain containing 2 [Homo sapiens]
Length = 655
Score = 67.0 bits (162), Expect = 1e-10
Identities = 37/104 (35%), Positives = 52/104 (50%), Gaps = 3/104 (2%)
Query: 700 SFNSNYIDIESNSEGGSSFVTANEDSVPENTCKEGLVLGQKQPTWVPDSEAPNCMNCQVK 759
+F + IE +E + E + E + LG + P WV D CM CQ
Sbjct: 412 AFQAAIDQIEKRNETFKAAAQGPEGDIQEQELQSE-ELGLRAPQWVRDKMVTMCMRCQEP 470
Query: 760 FT-FTKRRHHCRACGKVFCGVCCNRKCKLQYLE-KEARVCVVCY 801
F T+RRHHCRACG V C C + + +L+Y + + RVC+ CY
Sbjct: 471 FNALTRRRHHCRACGYVVCARCSDYRAELKYDDNRPNRVCLHCY 514
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 65.1 bits (157), Expect = 5e-10
Identities = 24/62 (38%), Positives = 36/62 (58%)
Query: 740 KQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLEKEARVCVV 799
K W+ D EA +C C+ +F+ ++R+HHCR CG +FC C + + L K RVC
Sbjct: 527 KGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVCDS 586
Query: 800 CY 801
C+
Sbjct: 587 CH 588
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 65.1 bits (157), Expect = 5e-10
Identities = 24/62 (38%), Positives = 36/62 (58%)
Query: 740 KQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLEKEARVCVV 799
K W+ D EA +C C+ +F+ ++R+HHCR CG +FC C + + L K RVC
Sbjct: 527 KGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVCDS 586
Query: 800 CY 801
C+
Sbjct: 587 CH 588
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
sapiens]
Length = 708
Score = 65.1 bits (157), Expect = 5e-10
Identities = 24/62 (38%), Positives = 36/62 (58%)
Query: 740 KQPTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLEKEARVCVV 799
K W+ D EA +C C+ +F+ ++R+HHCR CG +FC C + + L K RVC
Sbjct: 635 KGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVCDS 694
Query: 800 CY 801
C+
Sbjct: 695 CH 696
>gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens]
Length = 887
Score = 64.7 bits (156), Expect = 7e-10
Identities = 28/62 (45%), Positives = 36/62 (58%), Gaps = 2/62 (3%)
Query: 742 PTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKL-QYLE-KEARVCVV 799
P WVPD C C+ FT +R+HHCR+CGK+FC C + L +Y + K RVC
Sbjct: 812 PEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTH 871
Query: 800 CY 801
CY
Sbjct: 872 CY 873
>gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens]
Length = 2539
Score = 64.7 bits (156), Expect = 7e-10
Identities = 45/154 (29%), Positives = 64/154 (41%), Gaps = 8/154 (5%)
Query: 681 ADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFV---TANEDSVPENTCKEGLVL 737
+D+V+ + + ADP+ S + + G S + + E S P + V
Sbjct: 1740 SDSVIHLQEIVHQAADPETLPRSPSAEFSPAAPPGISSIHSPSLRERSFPPTQPSQEFVP 1799
Query: 738 GQKQPT---WVPDSEAPNCMNC-QVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQ-YLEK 792
P WVPD CM C + FT RRHHCR CG++ C C +K ++ E
Sbjct: 1800 PATPPARHQWVPDETESICMVCCREHFTMFNRRHHCRRCGRLVCSSCSTKKMVVEGCREN 1859
Query: 793 EARVCVVCYETISKAQAFERMMSPTGSNLKSNHS 826
ARVC CY +K E P + N S
Sbjct: 1860 PARVCDQCYSYCNKDVPEEPSEKPEALDSSKNES 1893
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 63.9 bits (154), Expect = 1e-09
Identities = 25/61 (40%), Positives = 32/61 (52%)
Query: 744 WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLEKEARVCVVCYET 803
W D+E NCM C F+ T RRHHCR CG +FC C + +K RVC C+
Sbjct: 1349 WAEDNEVQNCMACGKGFSVTVRRHHCRQCGNIFCAECSAKNALTPSSKKPVRVCDACFND 1408
Query: 804 I 804
+
Sbjct: 1409 L 1409
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 62.0 bits (149), Expect = 4e-09
Identities = 128/718 (17%), Positives = 257/718 (35%), Gaps = 53/718 (7%)
Query: 10 SDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQECVNSCASS 69
SD D D + N + D ++ +S++ S SS+ + S +S +S SS
Sbjct: 634 SDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSS 693
Query: 70 ETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLSSVDGGTSDEIQPLYMGRCSKPICDL 129
++S + S ++ + + + N D SS +SD S D
Sbjct: 694 DSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD----------SSNSSDS 743
Query: 130 ISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDHDSDTVREQQ 189
SD + ++++S + D ++DS D S+ SD+ S++ SD+
Sbjct: 744 -SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSD 802
Query: 190 NDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIVDFNMSSALT 249
+ SS+ + D++ SDS N S + N D + +S+ +
Sbjct: 803 SSNSSDSSDSS-----------DSSDSDSSNSSDSSNSSDSSD----------SSNSSDS 841
Query: 250 RQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTSALTCSLPKN 309
SS D D + + + + + E +S + S +
Sbjct: 842 SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSS 901
Query: 310 EDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDSSSALHVSSK 369
+ + SNS D + D S D + S+ + S +D S S+ S
Sbjct: 902 DSDSSDSSNSSDSS----DSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSS 957
Query: 370 DVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNSVVLGGEPFK 429
+ S + +S S +S D + D+ + + + + +
Sbjct: 958 NSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSN 1017
Query: 430 ENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVESQEGLSGTHV 489
+D + S D D + ++S + D+S + +S + +
Sbjct: 1018 SSDSSNSSDSSNSSDSSDSSDSSDSS-DSSDSSDSSDSSNSSDSSDSS-DSSDSSDSSDS 1075
Query: 490 PESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQYLQTTNIKS 549
+SSD E ++ SSN D D + D S S D+ + +++
Sbjct: 1076 SDSSDSSESSDSSDSSNSSDSSD----SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1131
Query: 550 FEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVDKQNTIENGL 609
++ + S S + + D + ++ ++++ +S + + D ++ ++
Sbjct: 1132 SSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1191
Query: 610 SLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTRSSKDLNKPD 669
S + +S S ++ S S +S S + + + SS N D
Sbjct: 1192 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSD 1251
Query: 670 VPDTIESEPSTADTVVPITCAIDSTADPQVSF---NSNYIDIESNSEGGSSFVTANED 724
D+ +S ST+D+ + +D Q N+N D +S+SEG S + ++D
Sbjct: 1252 SSDSSDSSDSTSDS--------NDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
Score = 51.6 bits (122), Expect = 6e-06
Identities = 127/729 (17%), Positives = 252/729 (34%), Gaps = 29/729 (3%)
Query: 6 KAAVSDLDKLLDDFEQNPDEQDYLQDVQNAYDSNHCSVSSELASSQRTSLLPKDQECVNS 65
K+ SD D D + D D ++ DSN S S S S + NS
Sbjct: 546 KSDSSDSDS--SDSSNSSDSSD--SSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNS 601
Query: 66 CASSETSYGTNESSLNEKTLKGLTSIQNEKNVTGLDLLS-SVDGGTSDEIQPLYMGRCSK 124
SS++S ++ S ++ + S ++E + + D S S D +SD
Sbjct: 602 SDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDN-------- 653
Query: 125 PICDLISDMGNLVHATNSEEDIKKLLPDDFKSNADSLIGLDLSSVSDTPCVSSTDHDSDT 184
SD + +++NS + D S++DS D S SD+ S + SD+
Sbjct: 654 ------SDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDS 707
Query: 185 VREQQNDISSELQNREIGGIKELGIKVDTTLSDSYNYSGTENLKDKKIFNQLESIVDFNM 244
+D SS+ N + + SDS N S + + D + D +
Sbjct: 708 SDSDSSD-SSDSSN---SNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSN 763
Query: 245 SSALTRQSSKMFHAKDKLQHKSQPCGLLKDVGLVKEEVDVAVITAAECLKEEGKTSALTC 304
SS + S + S D D + + + + + +
Sbjct: 764 SSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823
Query: 305 SLPKNEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDSSSAL 364
S N + SNS D + + + + + S S D D+ DSS +
Sbjct: 824 SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS- 882
Query: 365 HVSSKDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNSVVLG 424
S + +S +S S +S D D+ + + + +
Sbjct: 883 -SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNS 941
Query: 425 GEPFKENDLL-KQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVESQEG 483
+ +D + S + + + D + ++S D D+S + +S +
Sbjct: 942 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDS-SDSSDS 1000
Query: 484 LSGTHVPESSDCCEGFINTFSSNDMDGQDL--DYFNIDEGAKSGPLISDAELDAFLTEQY 541
+ + +SSD + ++ SSN D + + D S S D+ +
Sbjct: 1001 SNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1060
Query: 542 LQTTNIKSFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVDK 601
+++ ++ + S S + D N ++ ++++ +S + ++ D
Sbjct: 1061 SDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1120
Query: 602 QNTIENGLSLGEKSTIPVQQGLPTSKSEITNQLSVSDINSQSVGGARPKQLFSLPSRTRS 661
N+ ++ S + +S S ++ S S +S S + + S
Sbjct: 1121 SNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1180
Query: 662 SKDLNKPDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVTA 721
S + D D+ +S S+ + + ++D S +S+ S+S S +
Sbjct: 1181 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDS 1240
Query: 722 NEDSVPENT 730
++ S N+
Sbjct: 1241 SDSSDSSNS 1249
Score = 43.1 bits (100), Expect = 0.002
Identities = 79/423 (18%), Positives = 155/423 (36%), Gaps = 19/423 (4%)
Query: 309 NEDLCLNDSNSRDENFKLPDFSFQEDKTVIKQSAQEDSKSLDLKDNDVIQDSSSALHVSS 368
N D N +N D+N K + D S + S S + D+ DS S+ SS
Sbjct: 523 NSDSNGNGNNGNDDNDKSDSGKGKSD-----SSDSDSSDSSNSSDSSDSSDSDSSDSNSS 577
Query: 369 KDVPSSLSCLPASGSMCGSLIESKARGDFLPQHEHKDNIQDAVTIHEEIQNSVVLGGEPF 428
D SS S +S S +S D + D+ + + + +S
Sbjct: 578 SDSDSSDS--DSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSS-------- 627
Query: 429 KENDLLKQEKCKSILLQSLIEGMEDRKIDPDQTVIRAESLDGGDTSSTVVESQEGLSGTH 488
K KS S D D + + S D D+S + +S ++
Sbjct: 628 KSESDSSDSDSKSDSSDSNSSDSSDNS-DSSDSSNSSNSSDSSDSSDS-SDSSSSSDSSN 685
Query: 489 VPESSDCCEGFINTFSSNDMDGQDLDYFNIDEGAKSGPLISDAELDAFLTEQYLQTTNIK 548
+SSD + ++ SS+ D D D + + + S SD+ + ++ +++
Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDS-SNSSDSS 744
Query: 549 SFEENVNDSKSQMNQIDMKGLDDGNINNIYFNAEAGAIGESHGINIICETVDKQNTIENG 608
++ N S S + D + ++ ++++ +S+ + ++ D N+ ++
Sbjct: 745 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS 804
Query: 609 LSLGEKSTIPVQQGLPTSKSEITNQLSVSD-INSQSVGGARPKQLFSLPSRTRSSKDLNK 667
S + ++ S+ +N SD NS + S + S N
Sbjct: 805 NSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNS 864
Query: 668 PDVPDTIESEPSTADTVVPITCAIDSTADPQVSFNSNYIDIESNSEGGSSFVTANEDSVP 727
D D+ +S S+ + + +++D S NS+ D +S S ++N
Sbjct: 865 SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSS 924
Query: 728 ENT 730
E++
Sbjct: 925 ESS 927
>gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Homo
sapiens]
Length = 281
Score = 62.0 bits (149), Expect = 4e-09
Identities = 26/70 (37%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
Query: 744 WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLE--KEARVCVVCY 801
WV D +C C V+F+ T+RRHHCR CG++FC C + +++ L+ RVC CY
Sbjct: 206 WVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 265
Query: 802 ETISKAQAFE 811
+ + E
Sbjct: 266 YNLQHERGSE 275
>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 3526
Score = 62.0 bits (149), Expect = 4e-09
Identities = 26/70 (37%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
Query: 744 WVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLE--KEARVCVVCY 801
WV D +C C V+F+ T+RRHHCR CG++FC C + +++ L+ RVC CY
Sbjct: 3451 WVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 3510
Query: 802 ETISKAQAFE 811
+ + E
Sbjct: 3511 YNLQHERGSE 3520
>gi|153791377 apoptosis-inducing protein D [Homo sapiens]
Length = 279
Score = 61.2 bits (147), Expect = 7e-09
Identities = 29/70 (41%), Positives = 37/70 (52%), Gaps = 2/70 (2%)
Query: 744 WVPDSEAPNCMNC-QVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLE-KEARVCVVCY 801
W+PD CM C Q +F+ RRHHCR CG V C C ++ L L K RVC +CY
Sbjct: 149 WIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFLLPRLSPKPVRVCSLCY 208
Query: 802 ETISKAQAFE 811
++ Q E
Sbjct: 209 RELAAQQRQE 218
>gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens]
Length = 1170
Score = 59.7 bits (143), Expect = 2e-08
Identities = 28/72 (38%), Positives = 37/72 (51%), Gaps = 11/72 (15%)
Query: 744 WVPDSEAPNCMNCQVKFTFTKRRHHCR---------ACGKVFCGVCCNRKCKL--QYLEK 792
W+PD A +C C F R+HHCR CG VFC CCN+K + Q L +
Sbjct: 1079 WLPDHLAAHCYACDSAFWLASRKHHCRDTDRVDQTWNCGNVFCSSCCNQKVPVPSQQLFE 1138
Query: 793 EARVCVVCYETI 804
+RVC CY ++
Sbjct: 1139 PSRVCKSCYSSL 1150
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,981,085
Number of Sequences: 37866
Number of extensions: 2717830
Number of successful extensions: 7761
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 7514
Number of HSP's gapped (non-prelim): 184
length of query: 1539
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1424
effective length of database: 13,892,928
effective search space: 19783529472
effective search space used: 19783529472
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.