BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|15718712 caspase 8 isoform E [Homo sapiens] (235 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|15718712 caspase 8 isoform E [Homo sapiens] 456 e-129 gi|122056476 caspase 8 isoform G precursor [Homo sapiens] 382 e-106 gi|15718706 caspase 8 isoform B precursor [Homo sapiens] 382 e-106 gi|122056474 caspase 8 isoform C precursor [Homo sapiens] 353 9e-98 gi|15718708 caspase 8 isoform C precursor [Homo sapiens] 353 9e-98 gi|15718704 caspase 8 isoform A precursor [Homo sapiens] 336 9e-93 gi|47078272 caspase 10 isoform d preproprotein [Homo sapiens] 88 7e-18 gi|47078269 caspase 10 isoform b preproprotein [Homo sapiens] 88 7e-18 gi|47078267 caspase 10 isoform a preproprotein [Homo sapiens] 88 7e-18 gi|187608585 CASP8 and FADD-like apoptosis regulator isoform 2 [... 72 4e-13 gi|187608577 CASP8 and FADD-like apoptosis regulator isoform 1 [... 72 4e-13 gi|187608571 CASP8 and FADD-like apoptosis regulator isoform 1 [... 72 4e-13 gi|4505229 Fas-associated via death domain [Homo sapiens] 49 3e-06 gi|58530842 desmoplakin isoform II [Homo sapiens] 42 5e-04 gi|4505705 phosphoprotein enriched in astrocytes 15 [Homo sapiens] 42 6e-04 gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 38 0.007 gi|30089960 CDC42-binding protein kinase alpha isoform A [Homo s... 36 0.025 gi|50980301 myosin phosphatase-Rho interacting protein isoform 2... 34 0.095 gi|50980307 myosin phosphatase-Rho interacting protein isoform 1... 34 0.095 gi|45439327 periplakin [Homo sapiens] 34 0.12 gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH po... 33 0.21 gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po... 33 0.21 gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo s... 33 0.21 gi|148596998 coiled-coil domain containing 122 [Homo sapiens] 33 0.21 gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 33 0.28 gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 33 0.28 gi|58530840 desmoplakin isoform I [Homo sapiens] 32 0.36 gi|52485606 formin-like 2 [Homo sapiens] 32 0.47 gi|150010604 kinesin family member 4B [Homo sapiens] 32 0.62 gi|89353287 death effector domain-containing protein [Homo sapiens] 32 0.62 >gi|15718712 caspase 8 isoform E [Homo sapiens] Length = 235 Score = 456 bits (1174), Expect = e-129 Identities = 235/235 (100%), Positives = 235/235 (100%) Query: 1 MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS 60 MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS Sbjct: 1 MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS 60 Query: 61 FLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSF 120 FLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSF Sbjct: 61 FLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSF 120 Query: 121 KFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEE 180 KFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEE Sbjct: 121 KFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEE 180 Query: 181 FSKERSSSLEGSPDEFSNDFGQSLPNEKQTSGILSDHQQSQFCKSTGESAQTSQH 235 FSKERSSSLEGSPDEFSNDFGQSLPNEKQTSGILSDHQQSQFCKSTGESAQTSQH Sbjct: 181 FSKERSSSLEGSPDEFSNDFGQSLPNEKQTSGILSDHQQSQFCKSTGESAQTSQH 235 >gi|122056476 caspase 8 isoform G precursor [Homo sapiens] Length = 538 Score = 382 bits (980), Expect = e-106 Identities = 198/198 (100%), Positives = 198/198 (100%) Query: 1 MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS 60 MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS Sbjct: 60 MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS 119 Query: 61 FLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSF 120 FLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSF Sbjct: 120 FLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSF 179 Query: 121 KFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEE 180 KFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEE Sbjct: 180 KFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEE 239 Query: 181 FSKERSSSLEGSPDEFSN 198 FSKERSSSLEGSPDEFSN Sbjct: 240 FSKERSSSLEGSPDEFSN 257 >gi|15718706 caspase 8 isoform B precursor [Homo sapiens] Length = 479 Score = 382 bits (980), Expect = e-106 Identities = 198/198 (100%), Positives = 198/198 (100%) Query: 1 MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS 60 MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS Sbjct: 1 MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS 60 Query: 61 FLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSF 120 FLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSF Sbjct: 61 FLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSF 120 Query: 121 KFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEE 180 KFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEE Sbjct: 121 KFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEE 180 Query: 181 FSKERSSSLEGSPDEFSN 198 FSKERSSSLEGSPDEFSN Sbjct: 181 FSKERSSSLEGSPDEFSN 198 >gi|122056474 caspase 8 isoform C precursor [Homo sapiens] Length = 464 Score = 353 bits (905), Expect = 9e-98 Identities = 183/183 (100%), Positives = 183/183 (100%) Query: 1 MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS 60 MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS Sbjct: 1 MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS 60 Query: 61 FLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSF 120 FLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSF Sbjct: 61 FLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSF 120 Query: 121 KFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEE 180 KFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEE Sbjct: 121 KFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEE 180 Query: 181 FSK 183 FSK Sbjct: 181 FSK 183 >gi|15718708 caspase 8 isoform C precursor [Homo sapiens] Length = 464 Score = 353 bits (905), Expect = 9e-98 Identities = 183/183 (100%), Positives = 183/183 (100%) Query: 1 MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS 60 MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS Sbjct: 1 MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS 60 Query: 61 FLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSF 120 FLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSF Sbjct: 61 FLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSF 120 Query: 121 KFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEE 180 KFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEE Sbjct: 121 KFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEE 180 Query: 181 FSK 183 FSK Sbjct: 181 FSK 183 >gi|15718704 caspase 8 isoform A precursor [Homo sapiens] Length = 496 Score = 336 bits (862), Expect = 9e-93 Identities = 183/215 (85%), Positives = 183/215 (85%), Gaps = 32/215 (14%) Query: 1 MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS 60 MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS Sbjct: 1 MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS 60 Query: 61 FLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAY------------------- 101 FLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAY Sbjct: 61 FLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRFHFCRMSWAEANSQCQTQ 120 Query: 102 -------------RVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEK 148 RVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEK Sbjct: 121 SVPFWRRVDHLLIRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEK 180 Query: 149 RVILGEGKLDILKRVCAQINKSLLKIINDYEEFSK 183 RVILGEGKLDILKRVCAQINKSLLKIINDYEEFSK Sbjct: 181 RVILGEGKLDILKRVCAQINKSLLKIINDYEEFSK 215 >gi|47078272 caspase 10 isoform d preproprotein [Homo sapiens] Length = 522 Score = 87.8 bits (216), Expect = 7e-18 Identities = 58/179 (32%), Positives = 94/179 (52%), Gaps = 7/179 (3%) Query: 1 MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS 60 + F L I L +D+ +LKFL + +P +K E A +F+ L + +L E + Sbjct: 18 VSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASDVFEHLLAEDLLSEEDPF 77 Query: 61 FLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSF 120 FL ELL+ I + LL +LN KEE+ER L P R ++S +R +LY++SE + L+ Sbjct: 78 FLAELLYIIRQKKLL-QHLNCTKEEVERLL--PTRQRVSLFRNLLYELSEGIDSENLKDM 134 Query: 121 KFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYE 179 FLL++ + K +M L +EK+ + E L L+ +C + LL+ I Y+ Sbjct: 135 IFLLKDSLPK----TEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPKLLRNIEKYK 189 >gi|47078269 caspase 10 isoform b preproprotein [Homo sapiens] Length = 521 Score = 87.8 bits (216), Expect = 7e-18 Identities = 58/179 (32%), Positives = 94/179 (52%), Gaps = 7/179 (3%) Query: 1 MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS 60 + F L I L +D+ +LKFL + +P +K E A +F+ L + +L E + Sbjct: 18 VSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASDVFEHLLAEDLLSEEDPF 77 Query: 61 FLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSF 120 FL ELL+ I + LL +LN KEE+ER L P R ++S +R +LY++SE + L+ Sbjct: 78 FLAELLYIIRQKKLL-QHLNCTKEEVERLL--PTRQRVSLFRNLLYELSEGIDSENLKDM 134 Query: 121 KFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYE 179 FLL++ + K +M L +EK+ + E L L+ +C + LL+ I Y+ Sbjct: 135 IFLLKDSLPK----TEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPKLLRNIEKYK 189 >gi|47078267 caspase 10 isoform a preproprotein [Homo sapiens] Length = 479 Score = 87.8 bits (216), Expect = 7e-18 Identities = 58/179 (32%), Positives = 94/179 (52%), Gaps = 7/179 (3%) Query: 1 MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS 60 + F L I L +D+ +LKFL + +P +K E A +F+ L + +L E + Sbjct: 18 VSFREKLLIIDSNLGVQDVENLKFLCIGLVPNKKLEKSSSASDVFEHLLAEDLLSEEDPF 77 Query: 61 FLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSF 120 FL ELL+ I + LL +LN KEE+ER L P R ++S +R +LY++SE + L+ Sbjct: 78 FLAELLYIIRQKKLL-QHLNCTKEEVERLL--PTRQRVSLFRNLLYELSEGIDSENLKDM 134 Query: 121 KFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYE 179 FLL++ + K +M L +EK+ + E L L+ +C + LL+ I Y+ Sbjct: 135 IFLLKDSLPK----TEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPKLLRNIEKYK 189 >gi|187608585 CASP8 and FADD-like apoptosis regulator isoform 2 [Homo sapiens] Length = 221 Score = 72.0 bits (175), Expect = 4e-13 Identities = 51/193 (26%), Positives = 103/193 (53%), Gaps = 15/193 (7%) Query: 7 LYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELL 66 ++ + E LD+++ L FL D ++D L + L+E+ L +L+ ELL Sbjct: 6 IHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDI---LRERGKLSVGDLA---ELL 59 Query: 67 FRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQE 126 +R+ R DLL L ++ +E L +S YRV++ +I E++ +S++ S FL+++ Sbjct: 60 YRVRRFDLLKRILKMDRKAVETHLLRNPHL-VSDYRVLMAEIGEDLDKSDVSSLIFLMKD 118 Query: 127 EISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKI-INDYEEFSKER 185 + + K+ + + LD+ +E+EK ++ +LD+L++ I++ LK I Y++ Sbjct: 119 YMGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQ----- 173 Query: 186 SSSLEGSPDEFSN 198 S++G+ + N Sbjct: 174 --SVQGAGTSYRN 184 Score = 45.8 bits (107), Expect = 3e-05 Identities = 32/122 (26%), Positives = 62/122 (50%), Gaps = 9/122 (7%) Query: 2 DFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSF 61 D+ + +IGE LD D++SL FL DY+ + K K L L L++ ++ L Sbjct: 92 DYRVLMAEIGEDLDKSDVSSLIFLMKDYMGRGKISKEKSFLDLVVELEKLNLVAPDQLDL 151 Query: 62 LKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFK 121 L++ L I+R+D L T+ ++ ++ +Q G ++YR +L ++ + +F+ Sbjct: 152 LEKCLKNIHRID-----LKTKIQKYKQSVQGAG----TSYRNVLQAAIQKSLKDPSNNFR 202 Query: 122 FL 123 + Sbjct: 203 MI 204 >gi|187608577 CASP8 and FADD-like apoptosis regulator isoform 1 [Homo sapiens] Length = 480 Score = 72.0 bits (175), Expect = 4e-13 Identities = 51/193 (26%), Positives = 103/193 (53%), Gaps = 15/193 (7%) Query: 7 LYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELL 66 ++ + E LD+++ L FL D ++D L + L+E+ L +L+ ELL Sbjct: 6 IHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDI---LRERGKLSVGDLA---ELL 59 Query: 67 FRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQE 126 +R+ R DLL L ++ +E L +S YRV++ +I E++ +S++ S FL+++ Sbjct: 60 YRVRRFDLLKRILKMDRKAVETHLLRNPHL-VSDYRVLMAEIGEDLDKSDVSSLIFLMKD 118 Query: 127 EISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKI-INDYEEFSKER 185 + + K+ + + LD+ +E+EK ++ +LD+L++ I++ LK I Y++ Sbjct: 119 YMGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQ----- 173 Query: 186 SSSLEGSPDEFSN 198 S++G+ + N Sbjct: 174 --SVQGAGTSYRN 184 Score = 45.1 bits (105), Expect = 5e-05 Identities = 32/120 (26%), Positives = 61/120 (50%), Gaps = 9/120 (7%) Query: 2 DFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSF 61 D+ + +IGE LD D++SL FL DY+ + K K L L L++ ++ L Sbjct: 92 DYRVLMAEIGEDLDKSDVSSLIFLMKDYMGRGKISKEKSFLDLVVELEKLNLVAPDQLDL 151 Query: 62 LKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFK 121 L++ L I+R+D L T+ ++ ++ +Q G ++YR +L ++ + +F+ Sbjct: 152 LEKCLKNIHRID-----LKTKIQKYKQSVQGAG----TSYRNVLQAAIQKSLKDPSNNFR 202 >gi|187608571 CASP8 and FADD-like apoptosis regulator isoform 1 [Homo sapiens] Length = 480 Score = 72.0 bits (175), Expect = 4e-13 Identities = 51/193 (26%), Positives = 103/193 (53%), Gaps = 15/193 (7%) Query: 7 LYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELL 66 ++ + E LD+++ L FL D ++D L + L+E+ L +L+ ELL Sbjct: 6 IHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDI---LRERGKLSVGDLA---ELL 59 Query: 67 FRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQE 126 +R+ R DLL L ++ +E L +S YRV++ +I E++ +S++ S FL+++ Sbjct: 60 YRVRRFDLLKRILKMDRKAVETHLLRNPHL-VSDYRVLMAEIGEDLDKSDVSSLIFLMKD 118 Query: 127 EISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKI-INDYEEFSKER 185 + + K+ + + LD+ +E+EK ++ +LD+L++ I++ LK I Y++ Sbjct: 119 YMGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQ----- 173 Query: 186 SSSLEGSPDEFSN 198 S++G+ + N Sbjct: 174 --SVQGAGTSYRN 184 Score = 45.1 bits (105), Expect = 5e-05 Identities = 32/120 (26%), Positives = 61/120 (50%), Gaps = 9/120 (7%) Query: 2 DFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSF 61 D+ + +IGE LD D++SL FL DY+ + K K L L L++ ++ L Sbjct: 92 DYRVLMAEIGEDLDKSDVSSLIFLMKDYMGRGKISKEKSFLDLVVELEKLNLVAPDQLDL 151 Query: 62 LKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFK 121 L++ L I+R+D L T+ ++ ++ +Q G ++YR +L ++ + +F+ Sbjct: 152 LEKCLKNIHRID-----LKTKIQKYKQSVQGAG----TSYRNVLQAAIQKSLKDPSNNFR 202 >gi|4505229 Fas-associated via death domain [Homo sapiens] Length = 208 Score = 49.3 bits (116), Expect = 3e-06 Identities = 27/69 (39%), Positives = 38/69 (55%) Query: 7 LYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELL 66 L+ + L S +L LKFL L + +RK E ++ L LF L E+ LE + L+ELL Sbjct: 8 LHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELLRELL 67 Query: 67 FRINRLDLL 75 + R DLL Sbjct: 68 ASLRRHDLL 76 Score = 42.7 bits (99), Expect = 3e-04 Identities = 24/80 (30%), Positives = 46/80 (57%), Gaps = 1/80 (1%) Query: 101 YRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDIL 160 + V+L+ +S +S SEL KFL + K KL+ + LD+F + ++ L G ++L Sbjct: 4 FLVLLHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELL 63 Query: 161 KRVCAQINK-SLLKIINDYE 179 + + A + + LL+ ++D+E Sbjct: 64 RELLASLRRHDLLRRVDDFE 83 >gi|58530842 desmoplakin isoform II [Homo sapiens] Length = 2272 Score = 42.0 bits (97), Expect = 5e-04 Identities = 41/159 (25%), Positives = 74/159 (46%), Gaps = 18/159 (11%) Query: 45 FQRLQEKRMLEESNLSF--------LKELLFRINRLDLLITYLNTRKEEMERELQTPGRA 96 + +LQ+ R E+ NL + +KE + I RL +L+ TRK E E EL Sbjct: 1139 YDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTRKREYENELAKASN- 1197 Query: 97 QISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILG--- 153 +I + Q+ +E S L K L Q++ +L+D++N +E E RV Sbjct: 1198 RIQESKNQCTQVVQE-RESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQRLEC 1256 Query: 154 -----EGKLDILKRVCAQINKSLLKIINDYEEFSKERSS 187 + L+ K ++ +++ KI ++ E+ +E++S Sbjct: 1257 EKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNS 1295 >gi|4505705 phosphoprotein enriched in astrocytes 15 [Homo sapiens] Length = 130 Score = 41.6 bits (96), Expect = 6e-04 Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 6/116 (5%) Query: 2 DFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSF 61 ++ L D+ + EDL LK + IP K E I F L+ L++ NLS+ Sbjct: 3 EYGTLLQDLTNNITLEDLEQLKSACKEDIPSEKSEEITTGSAWFSFLESHNKLDKDNLSY 62 Query: 62 LKELLFRINRLDLLITYLNTR------KEEMERELQTPGRAQISAYRVMLYQISEE 111 ++ + R DLL ++ R EE E + + Y+ ++ Q SEE Sbjct: 63 IEHIFEISRRPDLLTMVVDYRTRVLKISEEDELDTKLTRIPSAKKYKDIIRQPSEE 118 >gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] Length = 1979 Score = 38.1 bits (87), Expect = 0.007 Identities = 59/248 (23%), Positives = 98/248 (39%), Gaps = 32/248 (12%) Query: 4 SRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRL----QEKRMLEESNL 59 +RNL QL+ E L L Q+K I + +++ +E + + S+L Sbjct: 749 ARNLNTSALQLEHEHLIKLN--------QKKDMEIAELKKNIEQMDTDHKETKDVLSSSL 800 Query: 60 SFLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRS--EL 117 K+L IN+ ++ I L R +++ EL +Q +L Q EE RS + Sbjct: 801 EEQKQLTQLINKKEIFIEKLKERSSKLQEELDK--YSQALRKNEILRQTIEEKDRSLGSM 858 Query: 118 RSFKFLLQEEISKCKLDD-------DMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKS 170 + LQEE+ + + + D LD E+ V +L+ +K + K Sbjct: 859 KEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEV----SQLNTIKEHLEEEIKH 914 Query: 171 LLKIINDYEEFSKERSSSLEGSP---DEFSNDFGQSLPNEKQTSGILSDHQQSQFCKSTG 227 KII D + + SL+ DEF Q N T L ++ + + T Sbjct: 915 HQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQM--NATHTQLFLEKDEEIKSLQKTI 972 Query: 228 ESAQTSQH 235 E +T H Sbjct: 973 EQIKTQLH 980 Score = 28.5 bits (62), Expect = 5.2 Identities = 24/105 (22%), Positives = 44/105 (41%), Gaps = 10/105 (9%) Query: 82 RKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLD 141 R EE+E LQ G I +Y++ + + ++ + + E + K+ D Sbjct: 264 RIEELENLLQQGGSGVIETDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKD------ 317 Query: 142 IFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERS 186 + K++ E DIL+R Q+N +I+ + E E S Sbjct: 318 ----INKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLECS 358 >gi|30089960 CDC42-binding protein kinase alpha isoform A [Homo sapiens] Length = 1638 Score = 36.2 bits (82), Expect = 0.025 Identities = 49/213 (23%), Positives = 92/213 (43%), Gaps = 28/213 (13%) Query: 16 SEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLL 75 S+DL +K L + RKQ + ++ L Q+L+E + + L + +I + Sbjct: 484 SKDL-EIKNLKEEIEKLRKQ--VTESSHLEQQLEEANAVRQE----LDDAFRQIKAYEKQ 536 Query: 76 ITYLNTRKEEMER-ELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISK---- 130 I L +E++ + E+ T A ++ L + SE S+ + L Q++IS Sbjct: 537 IKTLQQEREDLNKLEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGV 596 Query: 131 CKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYE----------- 179 C ++ + + ++EK+ I E +L + + A K+L K ++D E Sbjct: 597 CSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIM 656 Query: 180 ----EFSKERSSSLEGSPDEFSNDFGQSLPNEK 208 + K R S + +EF ++F Q EK Sbjct: 657 ILKDKLEKTRRES-QSEREEFESEFKQQYEREK 688 >gi|50980301 myosin phosphatase-Rho interacting protein isoform 2 [Homo sapiens] Length = 1025 Score = 34.3 bits (77), Expect = 0.095 Identities = 31/101 (30%), Positives = 50/101 (49%), Gaps = 9/101 (8%) Query: 35 QEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMERELQTPG 94 Q+ I+D QR EK + EE + +E I+ ++ + N +EEMEREL+ Sbjct: 736 QKKIEDLQRQHQRELEK-LREEKDRLLAEETAATISAIEAM---KNAHREEMERELEKSQ 791 Query: 95 RAQISA----YRVMLYQISEEVSRSELRSFKFLLQEEISKC 131 R+QIS+ + Q EE+ +S R + L ++ KC Sbjct: 792 RSQISSVNSDVEALRRQYLEEL-QSVQRELEVLSEQYSQKC 831 >gi|50980307 myosin phosphatase-Rho interacting protein isoform 1 [Homo sapiens] Length = 1038 Score = 34.3 bits (77), Expect = 0.095 Identities = 31/101 (30%), Positives = 50/101 (49%), Gaps = 9/101 (8%) Query: 35 QEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMERELQTPG 94 Q+ I+D QR EK + EE + +E I+ ++ + N +EEMEREL+ Sbjct: 736 QKKIEDLQRQHQRELEK-LREEKDRLLAEETAATISAIEAM---KNAHREEMERELEKSQ 791 Query: 95 RAQISA----YRVMLYQISEEVSRSELRSFKFLLQEEISKC 131 R+QIS+ + Q EE+ +S R + L ++ KC Sbjct: 792 RSQISSVNSDVEALRRQYLEEL-QSVQRELEVLSEQYSQKC 831 >gi|45439327 periplakin [Homo sapiens] Length = 1756 Score = 33.9 bits (76), Expect = 0.12 Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 7/117 (5%) Query: 62 LKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVM-----LYQISEEVSRSE 116 + +L + RL T L + EE+ERE Q A+ R+ L Q E Sbjct: 1382 IDKLRAELRRLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKV 1441 Query: 117 LRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLK 173 + K +LQ++ + + + + L + E +R +L EG+L+ L+R A + K+ +K Sbjct: 1442 THTQKVVLQQDPQQAR-EHALLRLQLEEEQHRRQLL-EGELETLRRKLAALEKAEVK 1496 >gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH polyclonal antibodies [Homo sapiens] Length = 868 Score = 33.1 bits (74), Expect = 0.21 Identities = 57/238 (23%), Positives = 96/238 (40%), Gaps = 41/238 (17%) Query: 9 DIGEQLDSEDLASLKFL-SLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLF 67 +I QL E L K L SL + Q++++ ++ L Q+++EK + E Sbjct: 369 EIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQY-------- 420 Query: 68 RINRLDLLITY-LNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQE 126 R++ +T + + E EL+T G Q+SE + +L L+Q+ Sbjct: 421 ---RIEADVTKPIKPALKSAEVELKTGGNNS--------NQVSETDEKEDLLHENRLMQD 469 Query: 127 EISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERS 186 EI++ +L+ D +EK+ + +I+KR + K+L + E S Sbjct: 470 EIARLRLEKDTIKNQ---NLEKKYL---KDFEIVKRKHEDLQKALKRNEETLAETIACYS 523 Query: 187 SSLEGSPDEFS---------NDFGQSLPNEKQT-----SGILSDHQQSQFCKSTGESA 230 L DE + + GQ L E Q+ + L DH QS K E A Sbjct: 524 GQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELA 581 >gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH polyclonal antibodies [Homo sapiens] Length = 1430 Score = 33.1 bits (74), Expect = 0.21 Identities = 57/238 (23%), Positives = 96/238 (40%), Gaps = 41/238 (17%) Query: 9 DIGEQLDSEDLASLKFL-SLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLF 67 +I QL E L K L SL + Q++++ ++ L Q+++EK + E Sbjct: 931 EIKSQLKHETLELEKELCSLRFAIQQEKKKRRNVEELHQKVREKLRITEEQY-------- 982 Query: 68 RINRLDLLITY-LNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQE 126 R++ +T + + E EL+T G Q+SE + +L L+Q+ Sbjct: 983 ---RIEADVTKPIKPALKSAEVELKTGGNNS--------NQVSETDEKEDLLHENRLMQD 1031 Query: 127 EISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERS 186 EI++ +L+ D +EK+ + +I+KR + K+L + E S Sbjct: 1032 EIARLRLEKDTIKNQ---NLEKKYL---KDFEIVKRKHEDLQKALKRNEETLAETIACYS 1085 Query: 187 SSLEGSPDEFS---------NDFGQSLPNEKQT-----SGILSDHQQSQFCKSTGESA 230 L DE + + GQ L E Q+ + L DH QS K E A Sbjct: 1086 GQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHDQSHSSKRDQELA 1143 >gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo sapiens] Length = 1719 Score = 33.1 bits (74), Expect = 0.21 Identities = 34/147 (23%), Positives = 62/147 (42%), Gaps = 20/147 (13%) Query: 81 TRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISK----CKLDDD 136 T + + E E+ T A ++ L + SE S+ + L Q++IS C ++ Sbjct: 624 TERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEHQ 683 Query: 137 MNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYE---------------EF 181 + + ++EK+ I E +L + + A K+L K ++D E + Sbjct: 684 QEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILKDKL 743 Query: 182 SKERSSSLEGSPDEFSNDFGQSLPNEK 208 K R S + +EF ++F Q EK Sbjct: 744 EKTRRES-QSEREEFESEFKQQYEREK 769 >gi|148596998 coiled-coil domain containing 122 [Homo sapiens] Length = 273 Score = 33.1 bits (74), Expect = 0.21 Identities = 32/117 (27%), Positives = 59/117 (50%), Gaps = 19/117 (16%) Query: 56 ESNLSFLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRS 115 ES SF+ EL + + + L T KEE+ ++LQ PG +I+ Q+ E++ + Sbjct: 143 ESKWSFMTELHEKRD----FVKKLKTMKEELMQDLQNPGGNRIT-------QVQEDI--T 189 Query: 116 ELRSFKFLLQEEI--SKCKLDDDMNLLDIFIEMEKRVILGEGKLD-ILKRVCAQINK 169 L+ ++E I C L+++ + ++ K + + + D ILKR+ Q+NK Sbjct: 190 NLKDKIITVKESIIEKTCFLEEEKKTHE---KLRKEIEVQHKRYDAILKRLHCQVNK 243 >gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] Length = 1976 Score = 32.7 bits (73), Expect = 0.28 Identities = 52/221 (23%), Positives = 92/221 (41%), Gaps = 33/221 (14%) Query: 15 DSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKR-MLEE--SNLSFLKELLFRINR 71 D EDL S K D + + E K L Q+++E R LEE L ++ R+ Sbjct: 1512 DMEDLMSSK----DDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLE- 1566 Query: 72 LDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISE-EVSRSELRSFKFLLQEEISK 130 + K + ER+LQT R+++ Q+ E E + R + L SK Sbjct: 1567 -----VNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRAL--AVASK 1619 Query: 131 CKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLE 190 K++ D+ L E +++ + ++ K L K+ +++ +E + Sbjct: 1620 KKMEIDLKDL-------------EAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEA-R 1665 Query: 191 GSPDEFSNDFGQSLPNEKQTSGILSDHQQSQFCKSTGESAQ 231 S DE F QS +EK+ + ++ Q Q ++ E A+ Sbjct: 1666 ASRDEI---FAQSKESEKKLKSLEAEILQLQEELASSERAR 1703 Score = 31.6 bits (70), Expect = 0.62 Identities = 39/158 (24%), Positives = 71/158 (44%), Gaps = 21/158 (13%) Query: 6 NLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKEL 65 ++ D+ EQLD E+ A K + K + +++ ++L LE+ N F+KE Sbjct: 951 HIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILL---------LEDQNSKFIKEK 1001 Query: 66 LFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQ 125 +R+ + L +EE + L Q VM+ + E + + E K + Sbjct: 1002 KLMEDRIAECSSQL-AEEEEKAKNLAKIRNKQ----EVMISDLEERLKKEE----KTRQE 1052 Query: 126 EEISKCKLD-DDMNLLDIFIEMEKRVILGEGKLDILKR 162 E +K KLD + +L D E++ ++ E KL + K+ Sbjct: 1053 LEKAKRKLDGETTDLQDQIAELQAQI--DELKLQLAKK 1088 Score = 28.5 bits (62), Expect = 5.2 Identities = 26/98 (26%), Positives = 43/98 (43%), Gaps = 15/98 (15%) Query: 56 ESNLSFLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRS 115 ES L +ELL R L ++ + EE + LQ Q EE +R Sbjct: 1314 ESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQ-------------QEEEEEARK 1360 Query: 116 ELRSFKFLLQEEIS--KCKLDDDMNLLDIFIEMEKRVI 151 L LQ +++ K K+DDD+ ++ E +K+++ Sbjct: 1361 NLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLL 1398 >gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] Length = 2017 Score = 32.7 bits (73), Expect = 0.28 Identities = 30/120 (25%), Positives = 54/120 (45%), Gaps = 15/120 (12%) Query: 32 QRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMERELQ 91 +++QE AL Q+LQ++R L + L L+ L L K E+ER Sbjct: 1820 RQRQEGEAAALNTVQKLQDERRLLQERLGSLQRAL----------AQLEAEKREVER--- 1866 Query: 92 TPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVI 151 ++ RV L + ++V R +LRS + ++ K +LD + ++ + +R I Sbjct: 1867 --SALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQI 1924 Score = 28.9 bits (63), Expect = 4.0 Identities = 39/172 (22%), Positives = 73/172 (42%), Gaps = 12/172 (6%) Query: 28 DYIPQRKQEPIKDALMLFQRLQEK-RMLE--ESNLSFLKELLFRI----NRLDLLITYLN 80 D + + +++ ++D + + L+ R LE E S L + L + +R L L Sbjct: 641 DRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQ 700 Query: 81 TRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLL 140 K E+ L ++ M +EE S + S L E +++ KL D+N L Sbjct: 701 AEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKL--DLNRL 758 Query: 141 DIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGS 192 +E EK + G + + A+ + L+ + +E +++ LEGS Sbjct: 759 VAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQ---GLEGS 807 >gi|58530840 desmoplakin isoform I [Homo sapiens] Length = 2871 Score = 32.3 bits (72), Expect = 0.36 Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 20/106 (18%) Query: 45 FQRLQEKRMLEESNLSF--------LKELLFRINRLDLLITYLNTRKEEMEREL---QTP 93 + +LQ+ R E+ NL + +KE + I RL +L+ TRK E E EL + Sbjct: 1139 YDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTRKREYENELAKVRNH 1198 Query: 94 GRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNL 139 ++S R Y+ ++++ ++ EIS K DD NL Sbjct: 1199 YNEEMSNLR-NKYETEINITKTTIK--------EISMQKEDDSKNL 1235 >gi|52485606 formin-like 2 [Homo sapiens] Length = 1092 Score = 32.0 bits (71), Expect = 0.47 Identities = 34/143 (23%), Positives = 68/143 (47%), Gaps = 16/143 (11%) Query: 58 NLSFLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSEL 117 +++F L + +L L YL+ K +LQ QI AY ++ + + +E Sbjct: 333 DMNFRVHLQYEFTKLGL-DEYLDKLKHTESDKLQV----QIQAYLDNVFDVGALLEDAET 387 Query: 118 RSFKFLLQEEISKC------KLDDDMN-LLDIFIEMEKRVILGEGKLDILKRVCAQIN-- 168 ++ EE+ + KL D N + +E+EK+++ +LD+++ + N Sbjct: 388 KNAALERVEELEENISHLSEKLQDTENEAMSKIVELEKQLMQRNKELDVVREIYKDANTQ 447 Query: 169 -KSLLKIINDYEEFSKERSSSLE 190 +L K++ + EE + +R S+LE Sbjct: 448 VHTLRKMVKEKEE-AIQRQSTLE 469 >gi|150010604 kinesin family member 4B [Homo sapiens] Length = 1234 Score = 31.6 bits (70), Expect = 0.62 Identities = 33/115 (28%), Positives = 47/115 (40%), Gaps = 27/115 (23%) Query: 44 LFQRLQEKRMLEESNLSFLKELLFR-------------------INRLDLLITYLNTRKE 84 L Q K ++E +N LKE L R I L+L + L KE Sbjct: 517 LHQAQMSKEVVELNNALALKEALVRKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEKE 576 Query: 85 EMERELQTP----GRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDD 135 E+ RELQT +A++S +R L Q E ++ K L E+ KL + Sbjct: 577 ELVRELQTAKKNVNQAKLSEHRHKLLQELE----GQIADLKKKLNEQSKLLKLKE 627 >gi|89353287 death effector domain-containing protein [Homo sapiens] Length = 318 Score = 31.6 bits (70), Expect = 0.62 Identities = 20/66 (30%), Positives = 32/66 (48%) Query: 10 IGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRI 69 +G L D+ L FL +D I ++ I++ L+ + +ESN + +LL I Sbjct: 33 VGTHLTHRDVRVLSFLFVDVIDDHERGLIRNGRDFLLALERQGRCDESNFRQVLQLLRII 92 Query: 70 NRLDLL 75 R DLL Sbjct: 93 TRHDLL 98 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.134 0.357 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,882,914 Number of Sequences: 37866 Number of extensions: 330920 Number of successful extensions: 1307 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 21 Number of HSP's successfully gapped in prelim test: 57 Number of HSP's that attempted gapping in prelim test: 1234 Number of HSP's gapped (non-prelim): 105 length of query: 235 length of database: 18,247,518 effective HSP length: 99 effective length of query: 136 effective length of database: 14,498,784 effective search space: 1971834624 effective search space used: 1971834624 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.