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Search of human proteins with 156546910
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156546910 BRAF35/HDAC2 complex isoform b [Homo sapiens]
(634 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156546910 BRAF35/HDAC2 complex isoform b [Homo sapiens] 1261 0.0
gi|156546894 BRAF35/HDAC2 complex isoform a [Homo sapiens] 1211 0.0
gi|209529726 PHD finger protein 21B isoform 2 [Homo sapiens] 295 1e-79
gi|19923937 PHD finger protein 21B isoform 1 [Homo sapiens] 286 3e-77
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 78 3e-14
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa... 76 8e-14
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ... 76 1e-13
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ... 76 1e-13
gi|158420731 chromodomain helicase DNA binding protein 3 isoform... 76 1e-13
gi|74027251 tripartite motif-containing 33 protein isoform beta ... 72 2e-12
gi|74027249 tripartite motif-containing 33 protein isoform alpha... 72 2e-12
gi|38788260 bromodomain PHD finger transcription factor isoform ... 67 5e-11
gi|38788274 bromodomain PHD finger transcription factor isoform ... 67 5e-11
gi|4557291 autoimmune regulator isoform 1 [Homo sapiens] 66 9e-11
gi|4557293 autoimmune regulator isoform 2 [Homo sapiens] 66 9e-11
gi|209977097 tripartite motif-containing 66 [Homo sapiens] 66 9e-11
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 65 2e-10
gi|47419911 transcriptional intermediary factor 1 alpha isoform ... 64 4e-10
gi|47419909 transcriptional intermediary factor 1 alpha isoform ... 64 4e-10
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo... 62 2e-09
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 62 2e-09
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 62 2e-09
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 62 2e-09
gi|221139764 PHD and ring finger domains 1 [Homo sapiens] 60 8e-09
gi|116284392 mucin 2 precursor [Homo sapiens] 59 2e-08
gi|75677357 PHD finger protein 12 isoform 1 [Homo sapiens] 59 2e-08
gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo ... 59 2e-08
gi|30842829 PHD finger protein 12 isoform 2 [Homo sapiens] 59 2e-08
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 57 4e-08
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 57 4e-08
>gi|156546910 BRAF35/HDAC2 complex isoform b [Homo sapiens]
Length = 634
Score = 1261 bits (3263), Expect = 0.0
Identities = 634/634 (100%), Positives = 634/634 (100%)
Query: 1 MELQTLQEALKVEIQVHQKLVAQMKQDPQNADLKKQLHELQAKITALSEKQKRVVEQLRK 60
MELQTLQEALKVEIQVHQKLVAQMKQDPQNADLKKQLHELQAKITALSEKQKRVVEQLRK
Sbjct: 1 MELQTLQEALKVEIQVHQKLVAQMKQDPQNADLKKQLHELQAKITALSEKQKRVVEQLRK 60
Query: 61 NLIVKQEQPDKFQIQPLPQSENKLQTAQQQPLQQLQQQQQYHHHHAQQSAAASPNLTASQ 120
NLIVKQEQPDKFQIQPLPQSENKLQTAQQQPLQQLQQQQQYHHHHAQQSAAASPNLTASQ
Sbjct: 61 NLIVKQEQPDKFQIQPLPQSENKLQTAQQQPLQQLQQQQQYHHHHAQQSAAASPNLTASQ 120
Query: 121 KTVTTASMITTKTLPLVLKAATATMPASVVGQRPTIAMVTAINSQKAVLSTDVQNTPVNL 180
KTVTTASMITTKTLPLVLKAATATMPASVVGQRPTIAMVTAINSQKAVLSTDVQNTPVNL
Sbjct: 121 KTVTTASMITTKTLPLVLKAATATMPASVVGQRPTIAMVTAINSQKAVLSTDVQNTPVNL 180
Query: 181 QTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFIPPPRLTPRPNFLPQVRPKPV 240
QTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFIPPPRLTPRPNFLPQVRPKPV
Sbjct: 181 QTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFIPPPRLTPRPNFLPQVRPKPV 240
Query: 241 AQNNIPIAPAPPPMLAAPQLIQRPVMLTKFTPTTLPTSQNSIHPVRVVNGQTATIAKTFP 300
AQNNIPIAPAPPPMLAAPQLIQRPVMLTKFTPTTLPTSQNSIHPVRVVNGQTATIAKTFP
Sbjct: 241 AQNNIPIAPAPPPMLAAPQLIQRPVMLTKFTPTTLPTSQNSIHPVRVVNGQTATIAKTFP 300
Query: 301 MAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQTVKSHTETDEKQTESRTITPPAAPKPKR 360
MAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQTVKSHTETDEKQTESRTITPPAAPKPKR
Sbjct: 301 MAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQTVKSHTETDEKQTESRTITPPAAPKPKR 360
Query: 361 EENPQKLAFMVSLGLVTHDHLEEIQSKRQERKRRTTANPVYSGAVFEPERKKSAVTYLNS 420
EENPQKLAFMVSLGLVTHDHLEEIQSKRQERKRRTTANPVYSGAVFEPERKKSAVTYLNS
Sbjct: 361 EENPQKLAFMVSLGLVTHDHLEEIQSKRQERKRRTTANPVYSGAVFEPERKKSAVTYLNS 420
Query: 421 TMHPGTRKRANEEHWPKGDIHEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGM 480
TMHPGTRKRANEEHWPKGDIHEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGM
Sbjct: 421 TMHPGTRKRANEEHWPKGDIHEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGM 480
Query: 481 WICPRCQDQMLKKEEAIPWPGTLAIVHSYIAYKAAKEEEKQKLLKWSSDLKQEREQLEQK 540
WICPRCQDQMLKKEEAIPWPGTLAIVHSYIAYKAAKEEEKQKLLKWSSDLKQEREQLEQK
Sbjct: 481 WICPRCQDQMLKKEEAIPWPGTLAIVHSYIAYKAAKEEEKQKLLKWSSDLKQEREQLEQK 540
Query: 541 VKQLSNSISKCMEMKNTILARQKEMHSSLEKVKQLIRLIHGIDLSKPVDSEATVGAISNG 600
VKQLSNSISKCMEMKNTILARQKEMHSSLEKVKQLIRLIHGIDLSKPVDSEATVGAISNG
Sbjct: 541 VKQLSNSISKCMEMKNTILARQKEMHSSLEKVKQLIRLIHGIDLSKPVDSEATVGAISNG 600
Query: 601 PDCTPPANAATSTPAPSPSSQSCTANCNQGEETK 634
PDCTPPANAATSTPAPSPSSQSCTANCNQGEETK
Sbjct: 601 PDCTPPANAATSTPAPSPSSQSCTANCNQGEETK 634
>gi|156546894 BRAF35/HDAC2 complex isoform a [Homo sapiens]
Length = 680
Score = 1211 bits (3134), Expect = 0.0
Identities = 625/681 (91%), Positives = 626/681 (91%), Gaps = 48/681 (7%)
Query: 1 MELQTLQEALKVEIQVHQKLVAQMKQDPQNADLKKQLHELQAKITALSEKQKRVVEQLRK 60
MELQTLQEALKVEIQVHQKLVAQMKQDPQNADLKKQLHELQAKITALSEKQKRVVEQLRK
Sbjct: 1 MELQTLQEALKVEIQVHQKLVAQMKQDPQNADLKKQLHELQAKITALSEKQKRVVEQLRK 60
Query: 61 NLIVKQEQPDKFQIQPLPQSENKLQTAQQQPLQQLQQQQQYHHHHAQQSAAASPNLTASQ 120
NLIVKQEQPDKFQIQPLPQSENKLQTAQQQPLQQLQQQQQYHHHHAQQSAAASPNLTASQ
Sbjct: 61 NLIVKQEQPDKFQIQPLPQSENKLQTAQQQPLQQLQQQQQYHHHHAQQSAAASPNLTASQ 120
Query: 121 KTVTTASMITTKTLPLVLKAATATMPASVVGQRPTIAMVTAINSQKAVLSTDVQNTPVNL 180
KTVTTASMITTKTLPLVLKAATATMPASVVGQRPTIAMVTAINSQKAVLSTDVQNTPVNL
Sbjct: 121 KTVTTASMITTKTLPLVLKAATATMPASVVGQRPTIAMVTAINSQKAVLSTDVQNTPVNL 180
Query: 181 QTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFIPPPRLTPRPNFLPQVRPKPV 240
QTSSKVTGPGAEAVQIVAKNTVTL VQATPPQPIKVPQFIPPPRLTPRPNFLPQVRPKPV
Sbjct: 181 QTSSKVTGPGAEAVQIVAKNTVTL-VQATPPQPIKVPQFIPPPRLTPRPNFLPQVRPKPV 239
Query: 241 AQNNIPIAPAPPPMLAAPQLIQRPVMLTKFTPTTLPTSQNSIHPVRVVNGQTATIAKTFP 300
AQNNIPIAPAPPPMLAAPQLIQRPVMLTKFTPTTLPTSQNSIHPVRVVNGQTATIAKTFP
Sbjct: 240 AQNNIPIAPAPPPMLAAPQLIQRPVMLTKFTPTTLPTSQNSIHPVRVVNGQTATIAKTFP 299
Query: 301 MAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQTVKSHTETDEKQTESRTITPPAAPKPKR 360
MAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQTVKSHTETDEKQTESRTITPPAAPKPKR
Sbjct: 300 MAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQTVKSHTETDEKQTESRTITPPAAPKPKR 359
Query: 361 EENPQKLAFMVSLGLVTHDHLEEIQSKRQERKRRTTANPVYSGAVFEPERKKSAVTYLNS 420
EENPQKLAFMVSLGLVTHDHLEEIQSKRQERKRRTTANPVYSGAVFEPERKKSAVTYLNS
Sbjct: 360 EENPQKLAFMVSLGLVTHDHLEEIQSKRQERKRRTTANPVYSGAVFEPERKKSAVTYLNS 419
Query: 421 TMHPGTRKRANEEHW--------------------------------------------- 435
TMHPGTRKR +
Sbjct: 420 TMHPGTRKRGRPPKYNAVLGFGALTPTSPQSSHPDSPENEKTETTFTFPAPVQPVSLPSP 479
Query: 436 --PKGDIHEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQDQMLKK 493
GDIHEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQDQMLKK
Sbjct: 480 TSTDGDIHEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQDQMLKK 539
Query: 494 EEAIPWPGTLAIVHSYIAYKAAKEEEKQKLLKWSSDLKQEREQLEQKVKQLSNSISKCME 553
EEAIPWPGTLAIVHSYIAYKAAKEEEKQKLLKWSSDLKQEREQLEQKVKQLSNSISKCME
Sbjct: 540 EEAIPWPGTLAIVHSYIAYKAAKEEEKQKLLKWSSDLKQEREQLEQKVKQLSNSISKCME 599
Query: 554 MKNTILARQKEMHSSLEKVKQLIRLIHGIDLSKPVDSEATVGAISNGPDCTPPANAATST 613
MKNTILARQKEMHSSLEKVKQLIRLIHGIDLSKPVDSEATVGAISNGPDCTPPANAATST
Sbjct: 600 MKNTILARQKEMHSSLEKVKQLIRLIHGIDLSKPVDSEATVGAISNGPDCTPPANAATST 659
Query: 614 PAPSPSSQSCTANCNQGEETK 634
PAPSPSSQSCTANCNQGEETK
Sbjct: 660 PAPSPSSQSCTANCNQGEETK 680
>gi|209529726 PHD finger protein 21B isoform 2 [Homo sapiens]
Length = 489
Score = 295 bits (754), Expect = 1e-79
Identities = 171/445 (38%), Positives = 253/445 (56%), Gaps = 39/445 (8%)
Query: 213 PIKVPQFIPPPRLTPR-PNFLPQVRPKPVAQNNIPIAPAPPPMLAAPQLIQRPVMLTKFT 271
P+ PQ RL + LPQVRPK + +++P+AP P Q+ +++
Sbjct: 49 PVTGPQVSSLQRLAGQGAAVLPQVRPKTLIPDSLPVAPGRDRPPKQPPTFQKATVVSVKN 108
Query: 272 PT-TLPTSQNSIHPVRVVNGQTATIAKTFPMAQLTS-------IVIATPGTRLA-GPQT- 321
P+ LPT+ N++ V Q +A+ +A S I+ +P A P T
Sbjct: 109 PSPALPTANNTVSHVPAPGSQPQALAEPAALASPLSSAGVAYAIISTSPSNAAAMAPSTA 168
Query: 322 --------------------VQLSKPSLEKQ---TVKSHTETDEKQTESRTITPPAAPKP 358
V + +P ++ Q T +S T+E ++ +P
Sbjct: 169 VSVVSDSIKVQPLLISADNKVIIIQPQVQTQPESTAESRPPTEEPSQGAQATKKKKEDRP 228
Query: 359 KREENPQKLAFMVSLGLVTHDHLEEIQSKRQERKRRTTANPVYSGAVFEPERKKSAVTYL 418
+ENP+K+AFMV+LGLVT +HLEEIQSKRQERKRR+TANP YSG + E ERK+ A YL
Sbjct: 229 PTQENPEKIAFMVALGLVTTEHLEEIQSKRQERKRRSTANPAYSG-LLETERKRLASNYL 287
Query: 419 NSTMHPGTRKRANEEHWPKGDI-HEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIP 477
N+ + RANE+ K +I H++ C+ C++ L C TC YHL CL+PPLKT P
Sbjct: 288 NNPLF--LTARANEDPCWKNEITHDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAP 345
Query: 478 KGMWICPRCQDQMLKKEEAIPWPGTLAIVHSYIAYKAAKEEEKQKLLKWSSDLKQEREQL 537
KG+W+CPRCQ + LKK+E +PW G LAIVHSY+ +K KEEEKQKLL+ S+L+ E +QL
Sbjct: 346 KGVWVCPRCQQKALKKDEGVPWTGMLAIVHSYVTHKTVKEEEKQKLLQRGSELQNEHQQL 405
Query: 538 EQKVKQLSNSISKCMEMKNTILARQKEMHSSLEKVKQLIRLIHGIDLSKPVDSEATVGAI 597
E++ ++L++++ KC+E+K ++LARQ+ SSL++++ L+RLI G L + + + +
Sbjct: 406 EERDRRLASAVQKCLELKTSLLARQRGTQSSLDRLRALLRLIQGEQLLQVTMTTTSPAPL 465
Query: 598 SNGPDCTPPANAATSTPAPSPSSQS 622
GP T P+ AAT P +
Sbjct: 466 LAGP-WTKPSVAATHPTVQHPQGHN 489
Score = 47.4 bits (111), Expect = 4e-05
Identities = 54/208 (25%), Positives = 86/208 (41%), Gaps = 41/208 (19%)
Query: 1 MELQTLQEALKVEIQVHQKLVAQMKQDPQNADLKKQLHELQAKITALSEKQK-------- 52
MELQ+ EAL VE+ HQ N DLKKQLHE Q +I ALS+KQ
Sbjct: 1 MELQSRPEALAVELARHQ-----------NGDLKKQLHERQPRIAALSDKQALGTITAVP 49
Query: 53 ---RVVEQLRK-----NLIVKQEQPDKFQIQPLPQSENKLQTAQQQPLQQLQQQQQYHHH 104
V L++ ++ Q +P LP + + + +Q P Q +
Sbjct: 50 VTGPQVSSLQRLAGQGAAVLPQVRPKTLIPDSLPVAPGRDRPPKQPPTFQKATVVSVKN- 108
Query: 105 HAQQSAAASPNLTASQKTVTTASMITTKTLPLVLKAATATMPAS------VVGQRPTIAM 158
SP L + TV+ ++ L AA A+ +S ++ P+ A
Sbjct: 109 -------PSPALPTANNTVSHVPAPGSQPQALAEPAALASPLSSAGVAYAIISTSPSNAA 161
Query: 159 VTAINSQKAVLSTDVQNTPVNLQTSSKV 186
A ++ +V+S ++ P+ + +KV
Sbjct: 162 AMAPSTAVSVVSDSIKVQPLLISADNKV 189
>gi|19923937 PHD finger protein 21B isoform 1 [Homo sapiens]
Length = 531
Score = 286 bits (733), Expect = 3e-77
Identities = 207/645 (32%), Positives = 310/645 (48%), Gaps = 137/645 (21%)
Query: 1 MELQTLQEALKVEIQVHQKLVAQMKQDPQNADLKKQLHELQAK------------ITALS 48
MELQ+ EAL VE+ HQ N DLKKQLHE Q + ITA+
Sbjct: 1 MELQSRPEALAVELARHQ-----------NGDLKKQLHERQPRIAALSDKQALGTITAVP 49
Query: 49 EKQKRVVEQLRKN----LIVKQEQPDKFQIQPLPQSENKLQTAQQQPLQQLQQQQQYHHH 104
+V R ++ Q +P LP + + + +Q P Q +
Sbjct: 50 VTGPQVSSLQRLAGQGAAVLPQVRPKTLIPDSLPVAPGRDRPPKQPPTFQKATVVSVKN- 108
Query: 105 HAQQSAAASPNLTASQKTVTTASMITTKTLPLVLKAATATMPAS------VVGQRPTIAM 158
SP L + TV+ ++ L AA A+ +S ++ P+ A
Sbjct: 109 -------PSPALPTANNTVSHVPAPGSQPQALAEPAALASPLSSAGVAYAIISTSPSNAA 161
Query: 159 VTAINSQKAVLSTDVQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQ 218
A ++ +V+S ++ P+ + +K
Sbjct: 162 AMAPSTAVSVVSDSIKVQPLLISADNK--------------------------------- 188
Query: 219 FIPPPRLTPRPNFLPQVRPKPVAQNNIPIAPAPPPMLAAPQLIQRPVMLTKFTPTTLPTS 278
PPPRL P+ P P+ +++P+ P P P L+ P+
Sbjct: 189 --PPPRLLSSPH--PATHHCPLHPSSLPLTP-PSPSLS-------------------PSP 224
Query: 279 QNSIHPVRVVNGQTATIAKTFPMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQTVKSHT 338
+ I V ++ Q T P++ S+P E+ +
Sbjct: 225 LHGIFQVIIIQPQVQT-----------------------QPESTAESRPPTEEPS--QGA 259
Query: 339 ETDEKQTESRTITPPAAPKPKREENPQKLAFMVSLGLVTHDHLEEIQSKRQERKRRTTAN 398
+ +K+ E R P +ENP+K+AFMV+LGLVT +HLEEIQSKRQERKRR+TAN
Sbjct: 260 QATKKKKEDR---------PPTQENPEKIAFMVALGLVTTEHLEEIQSKRQERKRRSTAN 310
Query: 399 PVYSGAVFEPERKKSAVTYLNSTMHPGTRKRANEEHWPKGDI-HEDFCSVCRKSGQLLMC 457
P YSG + E ERK+ A YLN+ + RANE+ K +I H++ C+ C++ L C
Sbjct: 311 PAYSG-LLETERKRLASNYLNNPLF--LTARANEDPCWKNEITHDEHCAACKRGANLQPC 367
Query: 458 DTCSRVYHLDCLDPPLKTIPKGMWICPRCQDQMLKKEEAIPWPGTLAIVHSYIAYKAAKE 517
TC YHL CL+PPLKT PKG+W+CPRCQ + LKK+E +PW G LAIVHSY+ +K KE
Sbjct: 368 GTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALKKDEGVPWTGMLAIVHSYVTHKTVKE 427
Query: 518 EEKQKLLKWSSDLKQEREQLEQKVKQLSNSISKCMEMKNTILARQKEMHSSLEKVKQLIR 577
EEKQKLL+ S+L+ E +QLE++ ++L++++ KC+E+K ++LARQ+ SSL++++ L+R
Sbjct: 428 EEKQKLLQRGSELQNEHQQLEERDRRLASAVQKCLELKTSLLARQRGTQSSLDRLRALLR 487
Query: 578 LIHGIDLSKPVDSEATVGAISNGPDCTPPANAATSTPAPSPSSQS 622
LI G L + + + + GP T P+ AAT P +
Sbjct: 488 LIQGEQLLQVTMTTTSPAPLLAGP-WTKPSVAATHPTVQHPQGHN 531
>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
sapiens]
Length = 1954
Score = 77.8 bits (190), Expect = 3e-14
Identities = 46/178 (25%), Positives = 85/178 (47%), Gaps = 29/178 (16%)
Query: 346 ESRTITPPAAPKPKREENP---QKLAFMVSLGLVTHDHLEEIQSKRQERKRRTTANPVYS 402
E+ TI+PP A P + P +K G ++ + +++ K + TA +
Sbjct: 218 ETVTISPPLAVSPPQVPQPVPIRKAKTKEGKGPGVRKKIKGSKDGKKKGKGKKTAGLKFR 277
Query: 403 GAVFEPERKKSAVT---------YLNSTMHPGT-------------RKRANEEHWPKGD- 439
+RKK + + + ++++H + ++R ++ GD
Sbjct: 278 FGGISNKRKKGSSSEEDEREESDFDSASIHSASVRSECSAALGKKSKRRRKKKRIDDGDG 337
Query: 440 ---IHEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQDQMLKKE 494
H+D+C VC++ G++++CDTC R YHL CLDP L+ P+G W CP C+ + ++ E
Sbjct: 338 YETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELEKAPEGKWSCPHCEKEGIQWE 395
Score = 74.7 bits (182), Expect = 2e-13
Identities = 30/54 (55%), Positives = 35/54 (64%)
Query: 439 DIHEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQDQMLK 492
D H +FC VC+ G+LL CD C YHL CL+PPL IP G W+CPRC LK
Sbjct: 413 DDHMEFCRVCKDGGELLCCDACPSSYHLHCLNPPLPEIPNGEWLCPRCTCPPLK 466
>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
sapiens]
Length = 1912
Score = 76.3 bits (186), Expect = 8e-14
Identities = 30/54 (55%), Positives = 36/54 (66%)
Query: 439 DIHEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQDQMLK 492
D H +FC VC+ G+LL CDTC YH+ CL+PPL IP G W+CPRC LK
Sbjct: 446 DHHMEFCRVCKDGGELLCCDTCPSSYHIHCLNPPLPEIPNGEWLCPRCTCPALK 499
Score = 74.7 bits (182), Expect = 2e-13
Identities = 24/54 (44%), Positives = 40/54 (74%)
Query: 441 HEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQDQMLKKE 494
H+D+C VC++ G++++CDTC R YH+ CLDP ++ P+G W CP C+ + ++ E
Sbjct: 369 HQDYCEVCQQGGEIILCDTCPRAYHMVCLDPDMEKAPEGKWSCPHCEKEGIQWE 422
Score = 37.4 bits (85), Expect = 0.043
Identities = 35/127 (27%), Positives = 53/127 (41%), Gaps = 11/127 (8%)
Query: 139 KAATATMPASVVGQRPTIA---MVTAINSQKAVLSTDVQNTPVNLQTSSKVTGPGAEAVQ 195
KA + + + + P IA M+ + ++ ST N P + + V A AV
Sbjct: 179 KAFSQFVRPLIAAKNPKIAVSKMMMVLGAKWREFST---NNPFKGSSGASVAAAAAAAVA 235
Query: 196 IVAKNTVTLQVQATPPQPIKVPQFIPPPRLTPRPNFLPQVRPKPVAQNNIPIAPAPPPML 255
+V ++ VT A PP P++VP + PN R KP +P A P P
Sbjct: 236 VV-ESMVTATEVAPPPPPVEVPIRKAKTKEGKGPN----ARRKPKGSPRVPDAKKPKPKK 290
Query: 256 AAPQLIQ 262
AP I+
Sbjct: 291 VAPLKIK 297
>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
[Homo sapiens]
Length = 2000
Score = 75.9 bits (185), Expect = 1e-13
Identities = 34/95 (35%), Positives = 52/95 (54%), Gaps = 20/95 (21%)
Query: 441 HEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQDQMLKKEEAIPWP 500
H+D+C VC++ G++++CDTC R YHL CLDP L P+G W CP C+ +E + W
Sbjct: 378 HQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCE------KEGVQW- 430
Query: 501 GTLAIVHSYIAYKAAKEEEKQKLLKWSSDLKQERE 535
AKEEE++ + + ++E E
Sbjct: 431 -------------EAKEEEEEYEEEGEEEGEKEEE 452
Score = 73.9 bits (180), Expect = 4e-13
Identities = 72/276 (26%), Positives = 104/276 (37%), Gaps = 31/276 (11%)
Query: 246 PIAPAPPPMLAAP---QLIQRPVMLTKFTPTTLPTSQNSIHPVRVVNGQTATIAKTFPMA 302
PIAP+ PP L P + P+ K P + RV +G+ K MA
Sbjct: 233 PIAPSGPPALPPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKK--MA 290
Query: 303 QLTSIVIATPGTRLAGPQTVQLSKPSLEKQTVKSHTETDEKQTES-RTITPPAAPKPKRE 361
L + G R G V S E + +S ++ + S R P K KR
Sbjct: 291 PLKIKLGLLGGKRKKGGSYVFQSDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRG 350
Query: 362 ENPQKLAFMVSLGLVT-----------HDHLEEIQSKRQERKRRTTANPVYSGAVFEPER 410
+K ++ V H E+ + E T Y +PE
Sbjct: 351 RPGRKKKKVLGCPAVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPEL 410
Query: 411 KKS-----AVTYLNSTMHPGTRKRANEEHWPKG---------DIHEDFCSVCRKSGQLLM 456
++ + + K EE+ +G D H ++C VC+ G+LL
Sbjct: 411 DRAPEGKWSCPHCEKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLC 470
Query: 457 CDTCSRVYHLDCLDPPLKTIPKGMWICPRCQDQMLK 492
CD C YH+ CL+PPL IP G W+CPRC +LK
Sbjct: 471 CDACISSYHIHCLNPPLPDIPNGEWLCPRCTCPVLK 506
>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
[Homo sapiens]
Length = 1966
Score = 75.9 bits (185), Expect = 1e-13
Identities = 34/95 (35%), Positives = 52/95 (54%), Gaps = 20/95 (21%)
Query: 441 HEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQDQMLKKEEAIPWP 500
H+D+C VC++ G++++CDTC R YHL CLDP L P+G W CP C+ +E + W
Sbjct: 378 HQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCE------KEGVQW- 430
Query: 501 GTLAIVHSYIAYKAAKEEEKQKLLKWSSDLKQERE 535
AKEEE++ + + ++E E
Sbjct: 431 -------------EAKEEEEEYEEEGEEEGEKEEE 452
Score = 73.9 bits (180), Expect = 4e-13
Identities = 72/276 (26%), Positives = 104/276 (37%), Gaps = 31/276 (11%)
Query: 246 PIAPAPPPMLAAP---QLIQRPVMLTKFTPTTLPTSQNSIHPVRVVNGQTATIAKTFPMA 302
PIAP+ PP L P + P+ K P + RV +G+ K MA
Sbjct: 233 PIAPSGPPALPPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKK--MA 290
Query: 303 QLTSIVIATPGTRLAGPQTVQLSKPSLEKQTVKSHTETDEKQTES-RTITPPAAPKPKRE 361
L + G R G V S E + +S ++ + S R P K KR
Sbjct: 291 PLKIKLGLLGGKRKKGGSYVFQSDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRG 350
Query: 362 ENPQKLAFMVSLGLVT-----------HDHLEEIQSKRQERKRRTTANPVYSGAVFEPER 410
+K ++ V H E+ + E T Y +PE
Sbjct: 351 RPGRKKKKVLGCPAVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPEL 410
Query: 411 KKS-----AVTYLNSTMHPGTRKRANEEHWPKG---------DIHEDFCSVCRKSGQLLM 456
++ + + K EE+ +G D H ++C VC+ G+LL
Sbjct: 411 DRAPEGKWSCPHCEKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLC 470
Query: 457 CDTCSRVYHLDCLDPPLKTIPKGMWICPRCQDQMLK 492
CD C YH+ CL+PPL IP G W+CPRC +LK
Sbjct: 471 CDACISSYHIHCLNPPLPDIPNGEWLCPRCTCPVLK 506
>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
[Homo sapiens]
Length = 2059
Score = 75.9 bits (185), Expect = 1e-13
Identities = 34/95 (35%), Positives = 52/95 (54%), Gaps = 20/95 (21%)
Query: 441 HEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQDQMLKKEEAIPWP 500
H+D+C VC++ G++++CDTC R YHL CLDP L P+G W CP C+ +E + W
Sbjct: 437 HQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCE------KEGVQW- 489
Query: 501 GTLAIVHSYIAYKAAKEEEKQKLLKWSSDLKQERE 535
AKEEE++ + + ++E E
Sbjct: 490 -------------EAKEEEEEYEEEGEEEGEKEEE 511
Score = 73.9 bits (180), Expect = 4e-13
Identities = 72/276 (26%), Positives = 104/276 (37%), Gaps = 31/276 (11%)
Query: 246 PIAPAPPPMLAAP---QLIQRPVMLTKFTPTTLPTSQNSIHPVRVVNGQTATIAKTFPMA 302
PIAP+ PP L P + P+ K P + RV +G+ K MA
Sbjct: 292 PIAPSGPPALPPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKK--MA 349
Query: 303 QLTSIVIATPGTRLAGPQTVQLSKPSLEKQTVKSHTETDEKQTES-RTITPPAAPKPKRE 361
L + G R G V S E + +S ++ + S R P K KR
Sbjct: 350 PLKIKLGLLGGKRKKGGSYVFQSDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRG 409
Query: 362 ENPQKLAFMVSLGLVT-----------HDHLEEIQSKRQERKRRTTANPVYSGAVFEPER 410
+K ++ V H E+ + E T Y +PE
Sbjct: 410 RPGRKKKKVLGCPAVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPEL 469
Query: 411 KKS-----AVTYLNSTMHPGTRKRANEEHWPKG---------DIHEDFCSVCRKSGQLLM 456
++ + + K EE+ +G D H ++C VC+ G+LL
Sbjct: 470 DRAPEGKWSCPHCEKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRVCKDGGELLC 529
Query: 457 CDTCSRVYHLDCLDPPLKTIPKGMWICPRCQDQMLK 492
CD C YH+ CL+PPL IP G W+CPRC +LK
Sbjct: 530 CDACISSYHIHCLNPPLPDIPNGEWLCPRCTCPVLK 565
>gi|74027251 tripartite motif-containing 33 protein isoform beta
[Homo sapiens]
Length = 1110
Score = 71.6 bits (174), Expect = 2e-12
Identities = 99/453 (21%), Positives = 162/453 (35%), Gaps = 33/453 (7%)
Query: 61 NLIVKQEQPDKFQIQPLPQSENKLQTAQQQPLQQL--QQQQQYHHHHAQQSAAASPNLTA 118
N++V Q P I P N Q Q QQ+ Q+ QQ QQ A P T
Sbjct: 489 NVVVGQVPPGTNHISKTPGQINLAQLRLQHMQQQVYAQKHQQLQQMRMQQPPAPVPTTTT 548
Query: 119 S--QKTVTTASMITTKTLPLVLKAATATMPASVVGQRPTIAMVTAINSQKAV---LSTDV 173
+ Q A + + P ++ T G M A N+ + +
Sbjct: 549 TTQQHPRQAAPQMLQQQPPRLISVQTMQRGNMNCGAFQAHQMRLAQNAARIPGIPRHSGP 608
Query: 174 QNTPVNLQTSSKVTGPG-AEAVQIVAKNTVTLQVQATPPQPIKVPQFIPPPRLTPRPNFL 232
Q + + + + PG A +V+ + T+ P P T
Sbjct: 609 QYSMMQPHLQRQHSNPGHAGPFPVVSVHNTTIN----PTSPTTATMANANRGPTSPSVTA 664
Query: 233 PQVRPKPVAQNNIPIAPAPPPML-------AAPQLIQRPVMLTKFTPTTLPTSQNSIHPV 285
++ P N+P P PP+ + L+ R + + P T S P
Sbjct: 665 IELIPSVTNPENLPSLPDIPPIQLEDAGSSSLDNLLSRYISGSHLPPQPTSTMNPSPGPS 724
Query: 286 RVVNGQTATIAKTFPMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQTVKSHTETDEKQT 345
+ G + P+ ++ + G+ + +T + + S + VK E T
Sbjct: 725 ALSPGSSGLSNSHTPVRPPSTSSTGSRGSCGSSGRTAEKTSLSFKSDQVKVKQEPG---T 781
Query: 346 ESRTITPPAAPKPKREENPQKLAFMVSLG-------LVTHDHLEEIQSKRQERKRRTTAN 398
E + K ++ E+ ++ A M+S L T+ HLE +
Sbjct: 782 EDEICSFSGGVKQEKTEDGRRSACMLSSPESSLTPPLSTNLHLESELDALASLENHVKIE 841
Query: 399 PVYSGAVFEPERKKSAV---TYLNSTMHPGTRKRANEEHWPKGDIHEDFCSVCRKSGQLL 455
P + S V + + S MH R + + D +ED+C+VC+ G LL
Sbjct: 842 PADMNESCKQSGLSSLVNGKSPIRSLMHRSARIGGDGNN-KDDDPNEDWCAVCQNGGDLL 900
Query: 456 MCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQD 488
C+ C +V+HL C P L + P G WIC C+D
Sbjct: 901 CCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRD 933
>gi|74027249 tripartite motif-containing 33 protein isoform alpha
[Homo sapiens]
Length = 1127
Score = 71.6 bits (174), Expect = 2e-12
Identities = 99/453 (21%), Positives = 162/453 (35%), Gaps = 33/453 (7%)
Query: 61 NLIVKQEQPDKFQIQPLPQSENKLQTAQQQPLQQL--QQQQQYHHHHAQQSAAASPNLTA 118
N++V Q P I P N Q Q QQ+ Q+ QQ QQ A P T
Sbjct: 489 NVVVGQVPPGTNHISKTPGQINLAQLRLQHMQQQVYAQKHQQLQQMRMQQPPAPVPTTTT 548
Query: 119 S--QKTVTTASMITTKTLPLVLKAATATMPASVVGQRPTIAMVTAINSQKAV---LSTDV 173
+ Q A + + P ++ T G M A N+ + +
Sbjct: 549 TTQQHPRQAAPQMLQQQPPRLISVQTMQRGNMNCGAFQAHQMRLAQNAARIPGIPRHSGP 608
Query: 174 QNTPVNLQTSSKVTGPG-AEAVQIVAKNTVTLQVQATPPQPIKVPQFIPPPRLTPRPNFL 232
Q + + + + PG A +V+ + T+ P P T
Sbjct: 609 QYSMMQPHLQRQHSNPGHAGPFPVVSVHNTTIN----PTSPTTATMANANRGPTSPSVTA 664
Query: 233 PQVRPKPVAQNNIPIAPAPPPML-------AAPQLIQRPVMLTKFTPTTLPTSQNSIHPV 285
++ P N+P P PP+ + L+ R + + P T S P
Sbjct: 665 IELIPSVTNPENLPSLPDIPPIQLEDAGSSSLDNLLSRYISGSHLPPQPTSTMNPSPGPS 724
Query: 286 RVVNGQTATIAKTFPMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQTVKSHTETDEKQT 345
+ G + P+ ++ + G+ + +T + + S + VK E T
Sbjct: 725 ALSPGSSGLSNSHTPVRPPSTSSTGSRGSCGSSGRTAEKTSLSFKSDQVKVKQEPG---T 781
Query: 346 ESRTITPPAAPKPKREENPQKLAFMVSLG-------LVTHDHLEEIQSKRQERKRRTTAN 398
E + K ++ E+ ++ A M+S L T+ HLE +
Sbjct: 782 EDEICSFSGGVKQEKTEDGRRSACMLSSPESSLTPPLSTNLHLESELDALASLENHVKIE 841
Query: 399 PVYSGAVFEPERKKSAV---TYLNSTMHPGTRKRANEEHWPKGDIHEDFCSVCRKSGQLL 455
P + S V + + S MH R + + D +ED+C+VC+ G LL
Sbjct: 842 PADMNESCKQSGLSSLVNGKSPIRSLMHRSARIGGDGNN-KDDDPNEDWCAVCQNGGDLL 900
Query: 456 MCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQD 488
C+ C +V+HL C P L + P G WIC C+D
Sbjct: 901 CCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRD 933
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 67.0 bits (162), Expect = 5e-11
Identities = 30/62 (48%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
Query: 426 TRKRANEEHWPKGDI-HEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICP 484
T A EE +G I ++D C VC K G LL C+TCS VYHL+C+ PPL+ +P+ W C
Sbjct: 373 TTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCE 432
Query: 485 RC 486
C
Sbjct: 433 VC 434
Score = 41.2 bits (95), Expect = 0.003
Identities = 107/548 (19%), Positives = 192/548 (35%), Gaps = 83/548 (15%)
Query: 114 PNLTASQKTVTTASMITTKTLPLVLKAATATMPASVVGQR--PTIAMVTAINSQKAVLST 171
PN + S T + + +IT + + + S +G+ T MV + + V++
Sbjct: 2163 PNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQP-GAPQQVMTQ 2221
Query: 172 DVQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQAT---PPQPIKVPQFIPPPRLTPR 228
++ PV+ S+ T + + T T +Q++ PP+P + + +LT
Sbjct: 2222 IIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQL 2281
Query: 229 PN---------FLPQVRPKPVAQ-----NNIPIAPAPPPMLAAPQLIQRPVMLTKFTP-- 272
+ Q + + Q + + P P L + V FTP
Sbjct: 2282 TQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLA 2341
Query: 273 ---TTLPTSQNSIHPVRVVNGQTATIA----------KTFPMAQLTSIVIATPGTRLAGP 319
TT T+ ++ G+ KT P AQ +S+ G A P
Sbjct: 2342 TTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSV-----GPAEAQP 2396
Query: 320 QTVQLS---KPSLEKQT-----VKSHTETDEKQTESRTITPPAAPKPKREENPQKLAFMV 371
QT Q S +P + Q+ V++ E + T S + A P + PQ A
Sbjct: 2397 QTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQ 2456
Query: 372 SLGLVTHDHLEEIQSKRQERKRRTTANPVYSGAVFEPERKKSAVTYLNSTMHPGTRKRAN 431
V +QS Q R R +T + + G + + T + P T +
Sbjct: 2457 PQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQ----QSQVQTTTSQPIPIQPHTSLQIP 2512
Query: 432 EEHWPKGDIHEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQDQML 491
+ P+ V K ++ + + P + + M +C +Q++
Sbjct: 2513 SQGQPQSQPQ-----VVMKHNAVI-----EHLKQKKSMTPAEREENQRMIVC----NQVM 2558
Query: 492 KKEEAIPWPGTLAIVHSYIAYKAAKEEEKQKLLKWSSDLKQEREQLEQKVKQLSNSISKC 551
K YI K KEE KQ K + E+++ +Q +LS + K
Sbjct: 2559 K----------------YILDKIDKEE-KQAAKKRKREESVEQKRSKQNATKLSALLFKH 2601
Query: 552 MEMKNTILARQKEMHSSLEKVKQLIRLIHGIDLSKPVDSEATVGAISNGPDCTPPANAAT 611
E + +++ + +++ L + + K D A + C P A
Sbjct: 2602 KEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPP 2661
Query: 612 STPAPSPS 619
+ PAP PS
Sbjct: 2662 APPAPPPS 2669
Score = 39.3 bits (90), Expect = 0.011
Identities = 84/364 (23%), Positives = 133/364 (36%), Gaps = 83/364 (22%)
Query: 73 QIQPLPQSENKLQTAQQQPLQQLQQQQQYHHHHAQQSAAASPNLTASQKTVTTASMITTK 132
Q+Q +PQ T P QQL Q AA PN T + T
Sbjct: 2304 QLQLIPQGV----TVLPGPGQQLMQ-------------AAMPNGTVQRFLFT-------- 2338
Query: 133 TLPLVLKAATATMPASVVGQRPTIAMVTAINSQKAVLSTDVQNTPVNLQTSSKVTGPGAE 192
PL A TA+ + V T A T Q + +Q T P A+
Sbjct: 2339 --PLATTATTASTTTTTVS---TTAAGTGEQRQSKLSP--------QMQVHQDKTLPPAQ 2385
Query: 193 AVQIVAKNTVTLQVQATPPQPIKVPQFIPPPRLTPRPNFLPQVRPKPVAQNNIPIAPAPP 252
+ + Q Q P PQ P P P+V+ + +++P P
Sbjct: 2386 SSSV---GPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPT 2442
Query: 253 ------PMLAA---PQLI---QRPVMLTKFTPTTL-PTSQNSIHPVRVVNGQTATIAKTF 299
P +AA PQ Q PV + + T + P++ + + P + QT T ++
Sbjct: 2443 HAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTT-SQPI 2501
Query: 300 PMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQTVKSHTETDEKQTESRTITPPAAPKPK 359
P+ TS+ I + G +P + Q V H E + +++TP +
Sbjct: 2502 PIQPHTSLQIPSQG------------QPQSQPQVVMKHNAVIEHLKQKKSMTP-----AE 2544
Query: 360 REENPQKLAFMVSLGLVTHDHLEEI-QSKRQERKRRTTANPVYSGAVFEPERKKSAVTYL 418
REEN + M+ V L++I + ++Q K+R V E +R K T L
Sbjct: 2545 REENQR----MIVCNQVMKYILDKIDKEEKQAAKKRKREESV------EQKRSKQNATKL 2594
Query: 419 NSTM 422
++ +
Sbjct: 2595 SALL 2598
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 67.0 bits (162), Expect = 5e-11
Identities = 30/62 (48%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
Query: 426 TRKRANEEHWPKGDI-HEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICP 484
T A EE +G I ++D C VC K G LL C+TCS VYHL+C+ PPL+ +P+ W C
Sbjct: 373 TTNIAREELMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCE 432
Query: 485 RC 486
C
Sbjct: 433 VC 434
Score = 40.0 bits (92), Expect = 0.007
Identities = 83/382 (21%), Positives = 142/382 (37%), Gaps = 58/382 (15%)
Query: 66 QEQPDKFQIQPLPQSENKLQTAQQQPLQ---QLQQQQQYHHH--------HAQQSAAASP 114
+ QP Q PQ + + Q+ Q +Q ++Q Q H HAQ S
Sbjct: 2267 EAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVA 2326
Query: 115 NLTASQKTVTTASMITTKTLPLVLKAATATMPASVVGQRPTIAMVTAI-------NSQKA 167
+ Q V S + ++ P + +T GQ+ + T+ S +
Sbjct: 2327 AQSQPQSNVQGQSPVRVQS-PSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQI 2385
Query: 168 VLSTDVQNTP-VNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFIPPPRLT 226
Q+ P V T + +G V + + + LQ+Q PQ I VPQ L
Sbjct: 2386 PSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQ------LQ 2439
Query: 227 PRPNFLPQVRPKPVAQNNIPIAPAPPPMLAAPQLIQRPVMLTKFTPTTLPTSQNSIHPVR 286
+ L Q++ + VAQ + P + +Q P+ + + + QN
Sbjct: 2440 QQVQVLSQIQSQVVAQIQAQQSGVPQQI-----KLQLPIQIQQSSAVQTHQIQN------ 2488
Query: 287 VVNGQTATIAKTFPMAQL---TSIVIATPGTRLAGPQTVQLSKPS--LEKQTVKSHTETD 341
VV Q A++ + Q + T+Q S S ++KQ V H
Sbjct: 2489 VVTVQAASVQEQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVI 2548
Query: 342 EKQTESRTITPPAAPKPKREENPQKLAFMVSLGLVTHDHLEEI-QSKRQERKRRTTANPV 400
E + +++TP +REEN + M+ V L++I + ++Q K+R V
Sbjct: 2549 EHLKQKKSMTP-----AEREENQR----MIVCNQVMKYILDKIDKEEKQAAKKRKREESV 2599
Query: 401 YSGAVFEPERKKSAVTYLNSTM 422
E +R K T L++ +
Sbjct: 2600 ------EQKRSKQNATKLSALL 2615
Score = 37.7 bits (86), Expect = 0.033
Identities = 117/577 (20%), Positives = 208/577 (36%), Gaps = 98/577 (16%)
Query: 73 QIQPLPQSENKLQTAQQQPLQQLQQQQQYHHHHAQQSAAASPNLTASQKTVTTASMITTK 132
Q+Q +PQ T P QQL Q AA PN T + T
Sbjct: 2178 QLQLIPQGV----TVLPGPGQQLMQ-------------AAMPNGTVQRFLFT-------- 2212
Query: 133 TLPLVLKAATATMPASVVGQRPTIAMVTAINSQKAVLSTDVQNTPVNLQTSSKVTGPGAE 192
PL A TA+ + V T A T Q + +Q T P A+
Sbjct: 2213 --PLATTATTASTTTTTVS---TTAAGTGEQRQSKLSP--------QMQVHQDKTLPPAQ 2259
Query: 193 AVQIVAKNTVTLQVQATPPQPIKVPQFIPPPRLTPRPNFLPQVRPKPVAQNNIPIAPAPP 252
+ + Q Q P PQ P P P+V+ + +++P P
Sbjct: 2260 SSSV---GPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPT 2316
Query: 253 ------PMLAA---PQLI---QRPVMLTKFTPTTL-PTSQNSIHPVRVVNGQTATIAKTF 299
P +AA PQ Q PV + + T + P++ + + P + QT T ++
Sbjct: 2317 HAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTT-SQPI 2375
Query: 300 PMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQTVKSHTETDEKQTESRTITPPAAPKPK 359
P+ TS+ I + G + PQ ++ QT+ T + + SR P+P+
Sbjct: 2376 PIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVS----SPSRPQLQIQQPQPQ 2431
Query: 360 REENPQKLAFMVSLGLVTHDHLEEIQSKR----QERKRRTTANPVYSGAVFEPERKKSAV 415
PQ + L + + +IQ+++ Q+ K + S AV + + ++ V
Sbjct: 2432 VIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAV-QTHQIQNVV 2490
Query: 416 TYLNSTMHPGT------RKRANEEHWPKGDIHEDFCSVCRKSGQLLMCDTCSR----VYH 465
T +++ R + ++ + +I + +++ + + H
Sbjct: 2491 TVQAASVQEQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEH 2550
Query: 466 LD---CLDPPLKTIPKGMWICPRCQDQMLKKEEAIPWPGTLAIVHSYIAYKAAKEEEKQK 522
L + P + + M +C +Q++K YI K KEE KQ
Sbjct: 2551 LKQKKSMTPAEREENQRMIVC----NQVMK----------------YILDKIDKEE-KQA 2589
Query: 523 LLKWSSDLKQEREQLEQKVKQLSNSISKCMEMKNTILARQKEMHSSLEKVKQLIRLIHGI 582
K + E+++ +Q +LS + K E + +++ + +++ L +
Sbjct: 2590 AKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDL 2649
Query: 583 DLSKPVDSEATVGAISNGPDCTPPANAATSTPAPSPS 619
+ K D A + C P A + PAP PS
Sbjct: 2650 KIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPS 2686
Score = 35.4 bits (80), Expect = 0.16
Identities = 67/314 (21%), Positives = 122/314 (38%), Gaps = 82/314 (26%)
Query: 6 LQEALKVEIQVHQKLVAQMKQD----PQNADLKK----------QLHELQAKIT---ALS 48
LQ+ ++V Q+ ++VAQ++ PQ L+ Q H++Q +T A
Sbjct: 2438 LQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASV 2497
Query: 49 EKQKRVVEQLRKNLIVKQEQPDKFQIQPLPQSENKLQTAQQQPLQQLQQQQQYHHHHAQQ 108
++Q + V+QLR +Q K Q Q + E+ LQ + Q + +Q+Q H+ +
Sbjct: 2498 QEQLQRVQQLR------DQQQKKKQQQIEIKREHTLQASNQSEI--IQKQVVMKHNAVIE 2549
Query: 109 SAAASPNLTASQKTVTTASMITTKTLPLVL--------KAATATMPASVVGQRPTIAMVT 160
++T +++ ++ + + +L +AA V Q+ + T
Sbjct: 2550 HLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNAT 2609
Query: 161 AINS---------------QKAVLSTDVQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQ 205
+++ ++A+L D+Q + +Q K ++I + +
Sbjct: 2610 KLSALLFKHKEQLRAEILKKRALLDKDLQ---IEVQEELK------RDLKIKKEKDLMQL 2660
Query: 206 VQATPPQPIKVPQFIPPPRLTPRPNFLPQVRPKPVAQNNIPIAPAPPPMLAAPQLIQRPV 265
QAT P P +TP P P PAPPP P +Q
Sbjct: 2661 AQATAVA-------APCPPVTPAP----------------PAPPAPPPSPPPPPAVQHTG 2697
Query: 266 MLTKFTPTTLPTSQ 279
+L+ TPT SQ
Sbjct: 2698 LLS--TPTLPAASQ 2709
Score = 30.8 bits (68), Expect = 4.0
Identities = 33/129 (25%), Positives = 48/129 (37%), Gaps = 18/129 (13%)
Query: 12 VEIQVHQKLVAQMKQDPQNADLKKQLHELQAKITALSE----KQKRVVEQLRKNLIVKQE 67
+ IQ H L + PQ+ ++Q+ LS Q V R L ++Q
Sbjct: 2375 IPIQPHTSLQIPSQGQPQSQP------QVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQP 2428
Query: 68 QPDKFQIQPLPQSENKLQTAQQQPLQQLQQQQQYHHH--------HAQQSAAASPNLTAS 119
QP + L Q L Q Q + Q+Q QQ QQS+A + +
Sbjct: 2429 QPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQN 2488
Query: 120 QKTVTTASM 128
TV AS+
Sbjct: 2489 VVTVQAASV 2497
>gi|4557291 autoimmune regulator isoform 1 [Homo sapiens]
Length = 545
Score = 66.2 bits (160), Expect = 9e-11
Identities = 25/46 (54%), Positives = 31/46 (67%)
Query: 441 HEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRC 486
+ED C+VCR G+L+ CD C R +HL CL PPL+ IP G W C C
Sbjct: 295 NEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSC 340
>gi|4557293 autoimmune regulator isoform 2 [Homo sapiens]
Length = 348
Score = 66.2 bits (160), Expect = 9e-11
Identities = 25/46 (54%), Positives = 31/46 (67%)
Query: 441 HEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRC 486
+ED C+VCR G+L+ CD C R +HL CL PPL+ IP G W C C
Sbjct: 98 NEDECAVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSC 143
>gi|209977097 tripartite motif-containing 66 [Homo sapiens]
Length = 1216
Score = 66.2 bits (160), Expect = 9e-11
Identities = 45/143 (31%), Positives = 63/143 (44%), Gaps = 20/143 (13%)
Query: 357 KPKREENPQKLAFMVSLGLVTHDHLEEIQSKRQERKRRTTANPVYSGAVFEPERKKSAVT 416
K K ++N Q +F++ + T I+ Q+R T P G +K VT
Sbjct: 881 KLKPQKNDQDGSFLLIIECGTESSSMSIKVS-QDRLSEATQAPGLEG-------RKVTVT 932
Query: 417 YLNSTMHPGTRKRANEEH-----------WPKGDI-HEDFCSVCRKSGQLLMCDTCSRVY 464
L P + EEH P I +EDFC+VC G+LL CD C +V+
Sbjct: 933 SLAGQRPPEVEGTSPEEHRLIPRTPGAKKGPPAPIENEDFCAVCLNGGELLCCDRCPKVF 992
Query: 465 HLDCLDPPLKTIPKGMWICPRCQ 487
HL C P L + P G W+C C+
Sbjct: 993 HLSCHVPALLSFPGGEWVCTLCR 1015
Score = 30.0 bits (66), Expect = 6.8
Identities = 51/222 (22%), Positives = 87/222 (39%), Gaps = 33/222 (14%)
Query: 71 KFQIQPLPQSENKLQTAQQQPLQQLQQQQQYHHHHAQQSAAASPNLTASQKTVTTASMIT 130
KF+++ + + L AQQ LQ Q + H QQ+ N Q S
Sbjct: 511 KFELEEMQKDLELLLQAQQPSLQLSQTKSP---QHLQQTIVGQINYIVRQ-PAPVQSQSQ 566
Query: 131 TKTLPLVLKAATATMPASVVGQRPTIAMVTAINSQKAVLSTDVQNTPVNL--------QT 182
+TL AT PAS G +P + + N+ A+ + TP+++ +
Sbjct: 567 EETL-----QATDEPPAS-QGSKPALPLDK--NTAAALPQASGEETPLSVPPVDSTIQHS 618
Query: 183 SSKVTGPGAEAVQIVA-KNTVTLQVQATPPQPIKVPQFIPPPRLTPRPNFLPQVRPKPVA 241
S V + ++ I+ NT+ +++ +T + PQ LT PQ P
Sbjct: 619 SPNVVRKHSTSLSIMGFSNTLEMELSSTRLERPLEPQIQSVSNLTAG---APQAVPS--- 672
Query: 242 QNNIPIAPAPPPMLAAPQLIQRPVMLTKFTPTTLPTSQNSIH 283
+ APP M+++ +Q M T + L T + +H
Sbjct: 673 -----LLSAPPKMVSSLTSVQNQAM-PSLTTSHLQTVPSLVH 708
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 64.7 bits (156), Expect = 2e-10
Identities = 35/90 (38%), Positives = 48/90 (53%), Gaps = 7/90 (7%)
Query: 445 CSVCRKSGQ----LLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQDQMLKKEEAIPWP 500
CS CR G+ +L CD+C R +H++C DPPL +PKGMWIC C+ + KK +
Sbjct: 272 CSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPK--KKGRKLLHE 329
Query: 501 GTLAIVHSYI-AYKAAKEEEKQKLLKWSSD 529
I Y K + KQ+LL +SD
Sbjct: 330 KAAQIKRRYAKPIGRPKNKLKQRLLSVTSD 359
Score = 30.0 bits (66), Expect = 6.8
Identities = 42/207 (20%), Positives = 81/207 (39%), Gaps = 26/207 (12%)
Query: 118 ASQKTVTTASMITTKTLPLVLKAATATMPASV------------VGQRPTIAMVTAINSQ 165
+S + + SM T P+ L T A++ G P + ++
Sbjct: 1761 SSSQQLAQCSMAANFTPPMQLAEIPETSNANIGLYERMGQSDFGAGHYPQPSATFSLAKL 1820
Query: 166 KAVLSTDVQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQ----FIP 221
+ + +T + ++ +++ + + ++ NT +Q+ +P PQ P
Sbjct: 1821 QQLTNTLIDHSLPYSHSAAVTSYANSASLSTPLSNTGLVQLSQSPHSVPGGPQAQATMTP 1880
Query: 222 PPRLTPRP-NFLPQVRPKPVAQNNIPIAPAP--PPMLAAPQLIQRPVMLTKFTPTTLPTS 278
PP LTP P N P + + +A +NI I+ + +A+ I +P T
Sbjct: 1881 PPNLTPPPMNLPPPLLQRNMAASNIGISHSQRLQTQIASKGHISMRTKSASLSPAA-ATH 1939
Query: 279 QNSIHPVRVVNGQTATIAKTFPMAQLT 305
Q+ I+ G++ T+A P LT
Sbjct: 1940 QSQIY------GRSQTVAMQGPARTLT 1960
>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
[Homo sapiens]
Length = 1050
Score = 63.9 bits (154), Expect = 4e-10
Identities = 27/69 (39%), Positives = 40/69 (57%), Gaps = 7/69 (10%)
Query: 420 STMHPGTRKRANEEHWPKGDIHEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKG 479
S +H G ++ + D +ED+C+VC+ G+LL C+ C +V+HL C P L P G
Sbjct: 811 SPLHVGETRKED-------DPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSG 863
Query: 480 MWICPRCQD 488
WIC C+D
Sbjct: 864 EWICTFCRD 872
>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
[Homo sapiens]
Length = 1016
Score = 63.9 bits (154), Expect = 4e-10
Identities = 27/69 (39%), Positives = 40/69 (57%), Gaps = 7/69 (10%)
Query: 420 STMHPGTRKRANEEHWPKGDIHEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKG 479
S +H G ++ + D +ED+C+VC+ G+LL C+ C +V+HL C P L P G
Sbjct: 777 SPLHVGETRKED-------DPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSG 829
Query: 480 MWICPRCQD 488
WIC C+D
Sbjct: 830 EWICTFCRD 838
>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
sapiens]
Length = 1483
Score = 61.6 bits (148), Expect = 2e-09
Identities = 32/118 (27%), Positives = 58/118 (49%), Gaps = 12/118 (10%)
Query: 445 CSVCRKSGQ---LLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQDQMLKKEEAIPWPG 501
C VCRK G+ L++CD C++ +HL CL P L +P G W CP CQ ++
Sbjct: 1187 CKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPATARRNSR----- 1241
Query: 502 TLAIVHSYIAYKAAKEEEKQKLLKWSSDLKQEREQLEQKVKQLSNSISKCMEMKNTIL 559
+Y A+++ E + + + ++E E+ + +V L K + K++++
Sbjct: 1242 ----GRNYTEESASEDSEDDESDEEEEEEEEEEEEEDYEVAGLRLRPRKTIRGKHSVI 1295
Score = 30.8 bits (68), Expect = 4.0
Identities = 23/76 (30%), Positives = 42/76 (55%), Gaps = 7/76 (9%)
Query: 2 ELQTLQEALKVEIQVHQKLVAQMKQDPQNADLKKQLHELQAKITALSEKQKRVVEQLRKN 61
EL++L + + E+ H+K A M ++ + LKK+ EL+ K L EK K E+ K
Sbjct: 517 ELRSLVQK-RYELLEHKKRWASMSEEQRKEYLKKKREELKKK---LKEKAK---ERREKE 569
Query: 62 LIVKQEQPDKFQIQPL 77
++ + E+ +++ Q L
Sbjct: 570 MLERLEKQKRYEDQEL 585
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 61.6 bits (148), Expect = 2e-09
Identities = 24/47 (51%), Positives = 32/47 (68%), Gaps = 4/47 (8%)
Query: 445 CSVCRKSGQ----LLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQ 487
CS CR G+ +L CD+C R +H++C DPPL +PKGMWIC C+
Sbjct: 265 CSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRMPKGMWICQICR 311
Score = 36.2 bits (82), Expect = 0.095
Identities = 57/203 (28%), Positives = 81/203 (39%), Gaps = 30/203 (14%)
Query: 173 VQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFIPPPRLTPRPN-F 231
+Q + V + + P + V+ N Q Q PP P + PQ PPP+ P P
Sbjct: 1619 MQQSSVQPAANCSIKSPQSCVVERPPSN----QQQQPPPPPPQQPQ-PPPPQPQPAPQPP 1673
Query: 232 LPQVRPKPVAQNNIPIAPAPPPMLAAPQLIQRPVMLTKFTPTTL--------PTSQNSIH 283
PQ +P+ Q P PPP P L Q M FTP + T SI+
Sbjct: 1674 PPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQCS-MNNSFTPAPMIMEIPESGSTGNISIY 1732
Query: 284 ---PVRVVNGQTATIAKTFPMA---QLTSIVI---ATPGTR----LAGPQTVQLSKPSLE 330
P G + + TF +A QLT+ ++ A P + + +V LS L
Sbjct: 1733 ERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGL- 1791
Query: 331 KQTVKSHTETDEKQTESRTITPP 353
Q SH Q ++ T+TPP
Sbjct: 1792 AQLAPSHPLAGTPQAQA-TMTPP 1813
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 61.6 bits (148), Expect = 2e-09
Identities = 24/47 (51%), Positives = 32/47 (68%), Gaps = 4/47 (8%)
Query: 445 CSVCRKSGQ----LLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQ 487
CS CR G+ +L CD+C R +H++C DPPL +PKGMWIC C+
Sbjct: 265 CSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRMPKGMWICQICR 311
Score = 36.2 bits (82), Expect = 0.095
Identities = 57/203 (28%), Positives = 81/203 (39%), Gaps = 30/203 (14%)
Query: 173 VQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFIPPPRLTPRPN-F 231
+Q + V + + P + V+ N Q Q PP P + PQ PPP+ P P
Sbjct: 1619 MQQSSVQPAANCSIKSPQSCVVERPPSN----QQQQPPPPPPQQPQ-PPPPQPQPAPQPP 1673
Query: 232 LPQVRPKPVAQNNIPIAPAPPPMLAAPQLIQRPVMLTKFTPTTL--------PTSQNSIH 283
PQ +P+ Q P PPP P L Q M FTP + T SI+
Sbjct: 1674 PPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQCS-MNNSFTPAPMIMEIPESGSTGNISIY 1732
Query: 284 ---PVRVVNGQTATIAKTFPMA---QLTSIVI---ATPGTR----LAGPQTVQLSKPSLE 330
P G + + TF +A QLT+ ++ A P + + +V LS L
Sbjct: 1733 ERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGL- 1791
Query: 331 KQTVKSHTETDEKQTESRTITPP 353
Q SH Q ++ T+TPP
Sbjct: 1792 AQLAPSHPLAGTPQAQA-TMTPP 1813
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 61.6 bits (148), Expect = 2e-09
Identities = 24/47 (51%), Positives = 32/47 (68%), Gaps = 4/47 (8%)
Query: 445 CSVCRKSGQ----LLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQ 487
CS CR G+ +L CD+C R +H++C DPPL +PKGMWIC C+
Sbjct: 265 CSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRMPKGMWICQICR 311
Score = 36.2 bits (82), Expect = 0.095
Identities = 57/203 (28%), Positives = 81/203 (39%), Gaps = 30/203 (14%)
Query: 173 VQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFIPPPRLTPRPN-F 231
+Q + V + + P + V+ N Q Q PP P + PQ PPP+ P P
Sbjct: 1619 MQQSSVQPAANCSIKSPQSCVVERPPSN----QQQQPPPPPPQQPQ-PPPPQPQPAPQPP 1673
Query: 232 LPQVRPKPVAQNNIPIAPAPPPMLAAPQLIQRPVMLTKFTPTTL--------PTSQNSIH 283
PQ +P+ Q P PPP P L Q M FTP + T SI+
Sbjct: 1674 PPQQQPQQQPQPQPQQPPPPPPPQQQPPLSQCS-MNNSFTPAPMIMEIPESGSTGNISIY 1732
Query: 284 ---PVRVVNGQTATIAKTFPMA---QLTSIVI---ATPGTR----LAGPQTVQLSKPSLE 330
P G + + TF +A QLT+ ++ A P + + +V LS L
Sbjct: 1733 ERIPGDFGAGSYSQPSATFSLAKLQQLTNTIMDPHAMPYSHSPAVTSYATSVSLSNTGL- 1791
Query: 331 KQTVKSHTETDEKQTESRTITPP 353
Q SH Q ++ T+TPP
Sbjct: 1792 AQLAPSHPLAGTPQAQA-TMTPP 1813
>gi|221139764 PHD and ring finger domains 1 [Homo sapiens]
Length = 1648
Score = 59.7 bits (143), Expect = 8e-09
Identities = 23/46 (50%), Positives = 30/46 (65%), Gaps = 3/46 (6%)
Query: 444 FCSVCRKSGQ---LLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRC 486
FC VC +S + LL+CD C YH++CLDPPL+ +P W CP C
Sbjct: 185 FCEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPEC 230
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 58.5 bits (140), Expect = 2e-08
Identities = 62/260 (23%), Positives = 77/260 (29%), Gaps = 15/260 (5%)
Query: 114 PNLTASQKTVTTASMITTKT------LPLVLKAATATMPASVVGQRPTIAMVTAINSQKA 167
P T S T TT + T T P+ A+T T+P + PT T +
Sbjct: 1480 PTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTP 1539
Query: 168 VLSTDVQNTPVNLQTSSKVT---GPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFIPPPR 224
T TP T+ T P T T P P + PPP
Sbjct: 1540 SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPT 1599
Query: 225 LTPRPNFLPQVRPKPVAQ----NNIPIAPAPPPMLAAPQLIQRPVMLTKFTP--TTLPTS 278
TP P P P PI P P P T TP TT P+
Sbjct: 1600 TTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSP 1659
Query: 279 QNSIHPVRVVNGQTATIAKTFPMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQTVKSHT 338
+ P + T T P + +T+ T T S P T S T
Sbjct: 1660 PTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTT 1719
Query: 339 ETDEKQTESRTITPPAAPKP 358
T T +P P P
Sbjct: 1720 TPSPPPTTMTTPSPTTTPSP 1739
Score = 54.3 bits (129), Expect = 3e-07
Identities = 55/240 (22%), Positives = 74/240 (30%), Gaps = 15/240 (6%)
Query: 121 KTVTTASMITTKTLPLVLKAATATMPASVVGQRPTIAMVTA--INSQKAVLSTDVQNTPV 178
K +TT S TT P +T T+P + PT T + ++T P
Sbjct: 1394 KCITTPSPPTTTPSPP--PTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPT 1451
Query: 179 NLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFIPPPRLTPRPNFLPQVRPK 238
+ T + T T T P P PPP TP P + P
Sbjct: 1452 TTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP- 1510
Query: 239 PVAQNNIPIAPAPPPMLAAPQLIQRPVMLTKFTPTTLPTSQNSIHPVRVVNGQTATIAKT 298
P + +P P P P T P T S + P+ T T
Sbjct: 1511 PASTTTLPPTTTPSP----------PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT 1560
Query: 299 FPMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQTVKSHTETDEKQTESRTITPPAAPKP 358
P T+ P T + P T S P++ T T T + T P P P
Sbjct: 1561 TPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSP 1620
Score = 53.9 bits (128), Expect = 4e-07
Identities = 58/254 (22%), Positives = 81/254 (31%), Gaps = 24/254 (9%)
Query: 114 PNLTASQKTVTTASMITTKTLPLVLKAATATMPASVVGQRPTIAM---VTAINSQKAVLS 170
P T +TT + T P + T T P + PT T + +
Sbjct: 1433 PPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTT 1492
Query: 171 TDVQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFIPPPRLTPRPN 230
T T + T++ +T P + T TL TP P PPP TP P
Sbjct: 1493 TPPPTTTPSPPTTTPITPPAS---------TTTLPPTTTPSPPTTTTT-TPPPTTTPSPP 1542
Query: 231 FLPQVRPKPVAQNNIPIAPAPPPMLAAPQLIQRPVMLTKFTPTTLPTSQNSIHPVRVVNG 290
+ P P + +P P P P T PTT P+ + P
Sbjct: 1543 TTTPITP-PTSTTTLPPTTTPSPP---------PTTTTTPPPTTTPSPPTTTTPSPPTIT 1592
Query: 291 QTATIAKTFPMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQTVKSHTETDEKQTESRTI 350
T T P T+ P T + P T ++ P+ T+ T T + T
Sbjct: 1593 TTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPT-STTTLPPTTTPSPPPTTTTTP 1651
Query: 351 TPPAAPKPKREENP 364
P P P P
Sbjct: 1652 PPTTTPSPPTTTTP 1665
Score = 49.7 bits (117), Expect = 8e-06
Identities = 41/165 (24%), Positives = 53/165 (32%), Gaps = 7/165 (4%)
Query: 201 TVTLQVQATPPQPIKVPQFIPPPRLTPRPNFLPQVRPKPVAQNNIPIA-PAPPPMLAAPQ 259
T T T P P PPP TP P P P + P P+PP +P
Sbjct: 1428 TTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSP- 1486
Query: 260 LIQRPVMLTKFTPTTLPTSQNSIHPVRVVNGQTATIAKTFPMAQLTSIVIATPGTRLAGP 319
P T P T S + P+ T T P T+ P T + P
Sbjct: 1487 ----PTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPP 1542
Query: 320 QTVQLSKPSLEKQTVKSHTETDEKQTESRTITPPAAPKPKREENP 364
T ++ P+ T+ T T + T P P P P
Sbjct: 1543 TTTPITPPT-STTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTP 1586
Score = 47.0 bits (110), Expect = 5e-05
Identities = 64/261 (24%), Positives = 87/261 (33%), Gaps = 21/261 (8%)
Query: 113 SPNLTASQKTVTTASMITTKTLPLVLKAATAT------MPASVVGQRPTIAMVTAINSQK 166
+P T +Q TT TT P T T + V PT +
Sbjct: 4003 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4062
Query: 167 AVLSTDVQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFI---PPP 223
+T V TP T + T P + T T Q PI + P P
Sbjct: 4063 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTP 4121
Query: 224 RLTPRPNFLPQVRPKPVAQNNIPI---APAPPPMLAAPQLIQRPVMLTKFTPTTLP-TSQ 279
T P P V P P P+ + P TPTT P T+
Sbjct: 4122 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4181
Query: 280 NSIHPVRVVNG-QTA--TIAKTFPMAQLTSIVIATPGTRLAGPQTVQ-LSKPSLEKQTVK 335
++ P G QT T T P+A+LT+ + P + PQT + S P E T+
Sbjct: 4182 TTVTPTPTPTGTQTGPPTHTSTAPIAELTT---SNPPPESSTPQTSRSTSSPLTESTTLL 4238
Query: 336 SHTETDEKQTESRTITPPAAP 356
S + T + + P AP
Sbjct: 4239 STLPPAIEMTSTAPPSTPTAP 4259
Score = 44.7 bits (104), Expect = 3e-04
Identities = 57/246 (23%), Positives = 78/246 (31%), Gaps = 23/246 (9%)
Query: 122 TVTTASMITTKTLPLVLKAATATMPASVVGQRPTIAMVTAINSQKAVLSTDVQNTPVNLQ 181
T TT + T P+ P Q PT +T +T V TP
Sbjct: 1887 TTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITT--------TTTVTPTPTPTG 1938
Query: 182 TSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFI---PPPRLTPRPNFLPQVRPK 238
T + T P + T T Q PI + P P T P P
Sbjct: 1939 TQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 1997
Query: 239 PVAQNNIPI---APAPPPMLAAPQLIQRPVMLTKFTPTTLP-TSQNSIHPVRVVNG-QTA 293
V P P P+ + P TPTT P T+ ++ P G QT
Sbjct: 1998 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2057
Query: 294 TIAKTFPMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQT---VKSHTETDEKQTESRTI 350
T T P+ T++ T P T ++ + T + T T T + T+
Sbjct: 2058 T---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2114
Query: 351 TPPAAP 356
TP P
Sbjct: 2115 TPTPTP 2120
Score = 43.9 bits (102), Expect = 5e-04
Identities = 60/261 (22%), Positives = 82/261 (31%), Gaps = 21/261 (8%)
Query: 113 SPNLTASQKTVTTASMITTKTLPLVLKAATAT------MPASVVGQRPTIAMVTAINSQK 166
+P T +Q TT TT P T T + V PT +
Sbjct: 1910 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1969
Query: 167 AVLSTDVQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFI---PPP 223
+T V TP T + T P + T T Q PI + P P
Sbjct: 1970 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTP 2028
Query: 224 RLTPRPNFLPQVRPKPVAQNNIPI---APAPPPMLAAPQLIQRPVMLTKFTPTTLP-TSQ 279
T P P V P P P+ + P TPTT P T+
Sbjct: 2029 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2088
Query: 280 NSIHPVRVVNG-QTATIAKTFPMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQT---VK 335
++ P G QT T T P+ T++ T P T ++ + T
Sbjct: 2089 TTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2145
Query: 336 SHTETDEKQTESRTITPPAAP 356
+ T T T + T+TP P
Sbjct: 2146 TQTPTTTPITTTTTVTPTPTP 2166
Score = 43.9 bits (102), Expect = 5e-04
Identities = 60/261 (22%), Positives = 82/261 (31%), Gaps = 21/261 (8%)
Query: 113 SPNLTASQKTVTTASMITTKTLPLVLKAATAT------MPASVVGQRPTIAMVTAINSQK 166
+P T +Q TT TT P T T + V PT +
Sbjct: 2071 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2130
Query: 167 AVLSTDVQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFI---PPP 223
+T V TP T + T P + T T Q PI + P P
Sbjct: 2131 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTP 2189
Query: 224 RLTPRPNFLPQVRPKPVAQNNIPI---APAPPPMLAAPQLIQRPVMLTKFTPTTLP-TSQ 279
T P P V P P P+ + P TPTT P T+
Sbjct: 2190 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2249
Query: 280 NSIHPVRVVNG-QTATIAKTFPMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQT---VK 335
++ P G QT T T P+ T++ T P T ++ + T
Sbjct: 2250 TTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2306
Query: 336 SHTETDEKQTESRTITPPAAP 356
+ T T T + T+TP P
Sbjct: 2307 TQTPTTTPITTTTTVTPTPTP 2327
Score = 43.9 bits (102), Expect = 5e-04
Identities = 60/261 (22%), Positives = 82/261 (31%), Gaps = 21/261 (8%)
Query: 113 SPNLTASQKTVTTASMITTKTLPLVLKAATAT------MPASVVGQRPTIAMVTAINSQK 166
+P T +Q TT TT P T T + V PT +
Sbjct: 2232 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2291
Query: 167 AVLSTDVQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFI---PPP 223
+T V TP T + T P + T T Q PI + P P
Sbjct: 2292 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTP 2350
Query: 224 RLTPRPNFLPQVRPKPVAQNNIPI---APAPPPMLAAPQLIQRPVMLTKFTPTTLP-TSQ 279
T P P V P P P+ + P TPTT P T+
Sbjct: 2351 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2410
Query: 280 NSIHPVRVVNG-QTATIAKTFPMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQT---VK 335
++ P G QT T T P+ T++ T P T ++ + T
Sbjct: 2411 TTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2467
Query: 336 SHTETDEKQTESRTITPPAAP 356
+ T T T + T+TP P
Sbjct: 2468 TQTPTTTPITTTTTVTPTPTP 2488
Score = 43.9 bits (102), Expect = 5e-04
Identities = 60/261 (22%), Positives = 82/261 (31%), Gaps = 21/261 (8%)
Query: 113 SPNLTASQKTVTTASMITTKTLPLVLKAATAT------MPASVVGQRPTIAMVTAINSQK 166
+P T +Q TT TT P T T + V PT +
Sbjct: 2393 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2452
Query: 167 AVLSTDVQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFI---PPP 223
+T V TP T + T P + T T Q PI + P P
Sbjct: 2453 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTP 2511
Query: 224 RLTPRPNFLPQVRPKPVAQNNIPI---APAPPPMLAAPQLIQRPVMLTKFTPTTLP-TSQ 279
T P P V P P P+ + P TPTT P T+
Sbjct: 2512 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2571
Query: 280 NSIHPVRVVNG-QTATIAKTFPMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQT---VK 335
++ P G QT T T P+ T++ T P T ++ + T
Sbjct: 2572 TTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2628
Query: 336 SHTETDEKQTESRTITPPAAP 356
+ T T T + T+TP P
Sbjct: 2629 TQTPTTTPITTTTTVTPTPTP 2649
Score = 43.9 bits (102), Expect = 5e-04
Identities = 60/261 (22%), Positives = 82/261 (31%), Gaps = 21/261 (8%)
Query: 113 SPNLTASQKTVTTASMITTKTLPLVLKAATAT------MPASVVGQRPTIAMVTAINSQK 166
+P T +Q TT TT P T T + V PT +
Sbjct: 2554 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2613
Query: 167 AVLSTDVQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFI---PPP 223
+T V TP T + T P + T T Q PI + P P
Sbjct: 2614 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTP 2672
Query: 224 RLTPRPNFLPQVRPKPVAQNNIPI---APAPPPMLAAPQLIQRPVMLTKFTPTTLP-TSQ 279
T P P V P P P+ + P TPTT P T+
Sbjct: 2673 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2732
Query: 280 NSIHPVRVVNG-QTATIAKTFPMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQT---VK 335
++ P G QT T T P+ T++ T P T ++ + T
Sbjct: 2733 TTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2789
Query: 336 SHTETDEKQTESRTITPPAAP 356
+ T T T + T+TP P
Sbjct: 2790 TQTPTTTPITTTTTVTPTPTP 2810
Score = 43.9 bits (102), Expect = 5e-04
Identities = 60/261 (22%), Positives = 82/261 (31%), Gaps = 21/261 (8%)
Query: 113 SPNLTASQKTVTTASMITTKTLPLVLKAATAT------MPASVVGQRPTIAMVTAINSQK 166
+P T +Q TT TT P T T + V PT +
Sbjct: 2715 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2774
Query: 167 AVLSTDVQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFI---PPP 223
+T V TP T + T P + T T Q PI + P P
Sbjct: 2775 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTP 2833
Query: 224 RLTPRPNFLPQVRPKPVAQNNIPI---APAPPPMLAAPQLIQRPVMLTKFTPTTLP-TSQ 279
T P P V P P P+ + P TPTT P T+
Sbjct: 2834 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2893
Query: 280 NSIHPVRVVNG-QTATIAKTFPMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQT---VK 335
++ P G QT T T P+ T++ T P T ++ + T
Sbjct: 2894 TTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2950
Query: 336 SHTETDEKQTESRTITPPAAP 356
+ T T T + T+TP P
Sbjct: 2951 TQTPTTTPITTTTTVTPTPTP 2971
Score = 43.9 bits (102), Expect = 5e-04
Identities = 60/261 (22%), Positives = 82/261 (31%), Gaps = 21/261 (8%)
Query: 113 SPNLTASQKTVTTASMITTKTLPLVLKAATAT------MPASVVGQRPTIAMVTAINSQK 166
+P T +Q TT TT P T T + V PT +
Sbjct: 2876 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2935
Query: 167 AVLSTDVQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFI---PPP 223
+T V TP T + T P + T T Q PI + P P
Sbjct: 2936 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTP 2994
Query: 224 RLTPRPNFLPQVRPKPVAQNNIPI---APAPPPMLAAPQLIQRPVMLTKFTPTTLP-TSQ 279
T P P V P P P+ + P TPTT P T+
Sbjct: 2995 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3054
Query: 280 NSIHPVRVVNG-QTATIAKTFPMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQT---VK 335
++ P G QT T T P+ T++ T P T ++ + T
Sbjct: 3055 TTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3111
Query: 336 SHTETDEKQTESRTITPPAAP 356
+ T T T + T+TP P
Sbjct: 3112 TQTPTTTPITTTTTVTPTPTP 3132
Score = 43.9 bits (102), Expect = 5e-04
Identities = 60/261 (22%), Positives = 82/261 (31%), Gaps = 21/261 (8%)
Query: 113 SPNLTASQKTVTTASMITTKTLPLVLKAATAT------MPASVVGQRPTIAMVTAINSQK 166
+P T +Q TT TT P T T + V PT +
Sbjct: 3037 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3096
Query: 167 AVLSTDVQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFI---PPP 223
+T V TP T + T P + T T Q PI + P P
Sbjct: 3097 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTP 3155
Query: 224 RLTPRPNFLPQVRPKPVAQNNIPI---APAPPPMLAAPQLIQRPVMLTKFTPTTLP-TSQ 279
T P P V P P P+ + P TPTT P T+
Sbjct: 3156 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3215
Query: 280 NSIHPVRVVNG-QTATIAKTFPMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQT---VK 335
++ P G QT T T P+ T++ T P T ++ + T
Sbjct: 3216 TTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3272
Query: 336 SHTETDEKQTESRTITPPAAP 356
+ T T T + T+TP P
Sbjct: 3273 TQTPTTTPITTTTTVTPTPTP 3293
Score = 43.9 bits (102), Expect = 5e-04
Identities = 60/261 (22%), Positives = 82/261 (31%), Gaps = 21/261 (8%)
Query: 113 SPNLTASQKTVTTASMITTKTLPLVLKAATAT------MPASVVGQRPTIAMVTAINSQK 166
+P T +Q TT TT P T T + V PT +
Sbjct: 3198 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3257
Query: 167 AVLSTDVQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFI---PPP 223
+T V TP T + T P + T T Q PI + P P
Sbjct: 3258 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTP 3316
Query: 224 RLTPRPNFLPQVRPKPVAQNNIPI---APAPPPMLAAPQLIQRPVMLTKFTPTTLP-TSQ 279
T P P V P P P+ + P TPTT P T+
Sbjct: 3317 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3376
Query: 280 NSIHPVRVVNG-QTATIAKTFPMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQT---VK 335
++ P G QT T T P+ T++ T P T ++ + T
Sbjct: 3377 TTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3433
Query: 336 SHTETDEKQTESRTITPPAAP 356
+ T T T + T+TP P
Sbjct: 3434 TQTPTTTPITTTTTVTPTPTP 3454
Score = 43.9 bits (102), Expect = 5e-04
Identities = 60/261 (22%), Positives = 82/261 (31%), Gaps = 21/261 (8%)
Query: 113 SPNLTASQKTVTTASMITTKTLPLVLKAATAT------MPASVVGQRPTIAMVTAINSQK 166
+P T +Q TT TT P T T + V PT +
Sbjct: 3359 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3418
Query: 167 AVLSTDVQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFI---PPP 223
+T V TP T + T P + T T Q PI + P P
Sbjct: 3419 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTP 3477
Query: 224 RLTPRPNFLPQVRPKPVAQNNIPI---APAPPPMLAAPQLIQRPVMLTKFTPTTLP-TSQ 279
T P P V P P P+ + P TPTT P T+
Sbjct: 3478 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3537
Query: 280 NSIHPVRVVNG-QTATIAKTFPMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQT---VK 335
++ P G QT T T P+ T++ T P T ++ + T
Sbjct: 3538 TTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3594
Query: 336 SHTETDEKQTESRTITPPAAP 356
+ T T T + T+TP P
Sbjct: 3595 TQTPTTTPITTTTTVTPTPTP 3615
Score = 43.9 bits (102), Expect = 5e-04
Identities = 60/261 (22%), Positives = 82/261 (31%), Gaps = 21/261 (8%)
Query: 113 SPNLTASQKTVTTASMITTKTLPLVLKAATAT------MPASVVGQRPTIAMVTAINSQK 166
+P T +Q TT TT P T T + V PT +
Sbjct: 3520 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3579
Query: 167 AVLSTDVQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFI---PPP 223
+T V TP T + T P + T T Q PI + P P
Sbjct: 3580 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTP 3638
Query: 224 RLTPRPNFLPQVRPKPVAQNNIPI---APAPPPMLAAPQLIQRPVMLTKFTPTTLP-TSQ 279
T P P V P P P+ + P TPTT P T+
Sbjct: 3639 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3698
Query: 280 NSIHPVRVVNG-QTATIAKTFPMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQT---VK 335
++ P G QT T T P+ T++ T P T ++ + T
Sbjct: 3699 TTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3755
Query: 336 SHTETDEKQTESRTITPPAAP 356
+ T T T + T+TP P
Sbjct: 3756 TQTPTTTPITTTTTVTPTPTP 3776
Score = 43.9 bits (102), Expect = 5e-04
Identities = 60/261 (22%), Positives = 82/261 (31%), Gaps = 21/261 (8%)
Query: 113 SPNLTASQKTVTTASMITTKTLPLVLKAATAT------MPASVVGQRPTIAMVTAINSQK 166
+P T +Q TT TT P T T + V PT +
Sbjct: 3681 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3740
Query: 167 AVLSTDVQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFI---PPP 223
+T V TP T + T P + T T Q PI + P P
Sbjct: 3741 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTP 3799
Query: 224 RLTPRPNFLPQVRPKPVAQNNIPI---APAPPPMLAAPQLIQRPVMLTKFTPTTLP-TSQ 279
T P P V P P P+ + P TPTT P T+
Sbjct: 3800 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3859
Query: 280 NSIHPVRVVNG-QTATIAKTFPMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQT---VK 335
++ P G QT T T P+ T++ T P T ++ + T
Sbjct: 3860 TTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3916
Query: 336 SHTETDEKQTESRTITPPAAP 356
+ T T T + T+TP P
Sbjct: 3917 TQTPTTTPITTTTTVTPTPTP 3937
Score = 43.9 bits (102), Expect = 5e-04
Identities = 60/261 (22%), Positives = 82/261 (31%), Gaps = 21/261 (8%)
Query: 113 SPNLTASQKTVTTASMITTKTLPLVLKAATAT------MPASVVGQRPTIAMVTAINSQK 166
+P T +Q TT TT P T T + V PT +
Sbjct: 3842 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3901
Query: 167 AVLSTDVQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFI---PPP 223
+T V TP T + T P + T T Q PI + P P
Sbjct: 3902 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTP 3960
Query: 224 RLTPRPNFLPQVRPKPVAQNNIPI---APAPPPMLAAPQLIQRPVMLTKFTPTTLP-TSQ 279
T P P V P P P+ + P TPTT P T+
Sbjct: 3961 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4020
Query: 280 NSIHPVRVVNG-QTATIAKTFPMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQT---VK 335
++ P G QT T T P+ T++ T P T ++ + T
Sbjct: 4021 TTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4077
Query: 336 SHTETDEKQTESRTITPPAAP 356
+ T T T + T+TP P
Sbjct: 4078 TQTPTTTPITTTTTVTPTPTP 4098
Score = 39.3 bits (90), Expect = 0.011
Identities = 53/248 (21%), Positives = 76/248 (30%), Gaps = 10/248 (4%)
Query: 113 SPNLTASQKTVTTASMITTKTLPLVLKAATATMPASVVGQRPTIAMVTAINSQKAVLSTD 172
+P T +Q TT TT P T T + + T+ + +T
Sbjct: 4072 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4131
Query: 173 VQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFIPPPRLTPRPNFL 232
+ T T + I TVT T Q +TP P
Sbjct: 4132 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4191
Query: 233 PQVRPKPVAQNNIPIAPA----PPPMLAAPQLIQRPVMLTKFTPTTLPTSQNSIHPVRVV 288
P + PIA PPP + PQ + + T L T +I
Sbjct: 4192 GTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTA 4251
Query: 289 NGQTATIAKT----FPMAQLTSIVIATPGTRLAGPQTVQLSKPSLEKQTVKSHTETDEKQ 344
T T T ++ S + PGT G T S P+ TV++ T +
Sbjct: 4252 PPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPT--PSTVQTTTTSAWTP 4309
Query: 345 TESRTITP 352
T + TP
Sbjct: 4310 TPTPLSTP 4317
Score = 33.9 bits (76), Expect = 0.47
Identities = 39/167 (23%), Positives = 54/167 (32%), Gaps = 10/167 (5%)
Query: 113 SPNLTASQKTVTTASMITTKTLPLVLKAATATMPASVVGQRPTIAMVTA-INSQKAVLST 171
SP T T+ + + T P T T P + PT + I + T
Sbjct: 1619 SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPT 1678
Query: 172 DVQNTPVNLQTS---SKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFIPPPRLTPR 228
++P+ S + +T P T T T P P P P TP
Sbjct: 1679 TTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPS 1738
Query: 229 PNFLPQVRPKPVAQNNIPIAPAP-PPMLAAPQLIQRPVMLTKFTPTT 274
P P ++ P+ P PP + P P T TPTT
Sbjct: 1739 PPTTTMTTLPPTTTSS-PLTTTPLPPSITPPTF--SPFSTT--TPTT 1780
Score = 31.6 bits (70), Expect = 2.3
Identities = 35/146 (23%), Positives = 45/146 (30%), Gaps = 15/146 (10%)
Query: 114 PNLTASQKTVTTASM-ITTKTLPLVLKAATATMPASVVGQRPTIAMVTAINSQKAVLSTD 172
P T S T TT S ITT T P T + P + PT M T T
Sbjct: 1653 PTTTPSPPTTTTPSPPITTTTTPP--PTTTPSSPITTTPSPPTTTMTTPS-------PTT 1703
Query: 173 VQNTPVNLQTSSKVTGPGAEAVQIVAKNTVTLQVQATPPQPIKVPQFIPPPRLTPRPNFL 232
++P+ T+ P + T+T T P P PP T P
Sbjct: 1704 TPSSPITTTTT-----PSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTT 1758
Query: 233 PQVRPKPVAQNNIPIAPAPPPMLAAP 258
+ P P + P P
Sbjct: 1759 TPLPPSITPPTFSPFSTTTPTTPCVP 1784
>gi|75677357 PHD finger protein 12 isoform 1 [Homo sapiens]
Length = 1004
Score = 58.5 bits (140), Expect = 2e-08
Identities = 26/72 (36%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 426 TRKRANEEHWPKGDIHEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPL--KTIPKGMWIC 483
+RK E + D C C++ G LL CD C +HL C +PPL + +P G W+C
Sbjct: 40 SRKPEKEPRRSGRATNHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGEWMC 99
Query: 484 PRCQDQMLKKEE 495
RC + K+E+
Sbjct: 100 HRCTVRRKKREQ 111
Score = 52.4 bits (124), Expect = 1e-06
Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 18/83 (21%)
Query: 420 STMHPGTRKRANEEHWPKGDI----HE-----------DFCSVCRKS---GQLLMCDTCS 461
+T PG+ KR +E ++ HE C C +S L+ CD C
Sbjct: 234 TTALPGSSKRRRKEETTGKNVKKTQHELDHNGLVPLPVKVCFTCNRSCRVAPLIQCDYCP 293
Query: 462 RVYHLDCLDPPLKTIPKGMWICP 484
++H+DCL+PPL +P G W+CP
Sbjct: 294 LLFHMDCLEPPLTAMPLGRWMCP 316
>gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo
sapiens]
Length = 1135
Score = 58.5 bits (140), Expect = 2e-08
Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 7/102 (6%)
Query: 386 SKRQERKRRTTANPVYSGAVFEPERKKSAVTYLNSTMHPGTRKRANEEHWPKGDIHEDFC 445
S + ++R +P +S P+ ++ + + PG N+E + D +C
Sbjct: 32 SAERTAQKRKFPSPPHSSNGHSPQ--DTSTSPIKKKKKPGLLNSNNKEQDGRNDF---YC 86
Query: 446 SVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQ 487
VC + GQ+L C+ C RVYH CL L + P+G W CP C+
Sbjct: 87 WVCHREGQVLCCELCPRVYHAKCL--RLTSEPEGDWFCPECE 126
>gi|30842829 PHD finger protein 12 isoform 2 [Homo sapiens]
Length = 704
Score = 58.5 bits (140), Expect = 2e-08
Identities = 26/72 (36%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 426 TRKRANEEHWPKGDIHEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPL--KTIPKGMWIC 483
+RK E + D C C++ G LL CD C +HL C +PPL + +P G W+C
Sbjct: 40 SRKPEKEPRRSGRATNHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGEWMC 99
Query: 484 PRCQDQMLKKEE 495
RC + K+E+
Sbjct: 100 HRCTVRRKKREQ 111
Score = 52.4 bits (124), Expect = 1e-06
Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 18/83 (21%)
Query: 420 STMHPGTRKRANEEHWPKGDI----HE-----------DFCSVCRKS---GQLLMCDTCS 461
+T PG+ KR +E ++ HE C C +S L+ CD C
Sbjct: 234 TTALPGSSKRRRKEETTGKNVKKTQHELDHNGLVPLPVKVCFTCNRSCRVAPLIQCDYCP 293
Query: 462 RVYHLDCLDPPLKTIPKGMWICP 484
++H+DCL+PPL +P G W+CP
Sbjct: 294 LLFHMDCLEPPLTAMPLGRWMCP 316
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 57.4 bits (137), Expect = 4e-08
Identities = 24/45 (53%), Positives = 29/45 (64%), Gaps = 3/45 (6%)
Query: 445 CSVCRKS---GQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRC 486
C C K+ G+LL+CD C YH CLDPPL+T+PKG W C C
Sbjct: 1010 CEACGKATDPGRLLLCDDCDISYHTYCLDPPLQTVPKGGWKCKWC 1054
Score = 50.8 bits (120), Expect = 4e-06
Identities = 19/46 (41%), Positives = 29/46 (63%), Gaps = 3/46 (6%)
Query: 445 CSVCRKSGQ---LLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQ 487
C C++SG+ +L+CDTC + YH CL P +K++P W C C+
Sbjct: 391 CQNCKQSGEDSKMLVCDTCDKGYHTFCLQPVMKSVPTNGWKCKNCR 436
Score = 41.6 bits (96), Expect = 0.002
Identities = 18/46 (39%), Positives = 24/46 (52%), Gaps = 3/46 (6%)
Query: 445 CSVCRKSGQLL---MCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQ 487
C+VC G LL C TC + YH CLD + + + W CP C+
Sbjct: 344 CAVCDSPGDLLDQFFCTTCGQHYHGMCLDIAVTPLKRAGWQCPECK 389
Score = 31.2 bits (69), Expect = 3.0
Identities = 67/322 (20%), Positives = 118/322 (36%), Gaps = 44/322 (13%)
Query: 25 KQDPQNADLKKQLHELQAKITALSEKQKRVVEQLRKNLIVKQEQPDKFQIQPLPQSENKL 84
K N +K+Q + Q I S + + K + EQ KF+ Q +S+ +
Sbjct: 1708 KVQMSNDSMKRQ--QQQDSIDPSSRIDSELFKDPLKQRESEHEQEWKFRQQMRQKSKQQA 1765
Query: 85 QTAQQQPLQQLQQQQQYHHHHAQQSAAASPNLTASQKTVTTASMITTKTLPLVLKAATAT 144
+ Q L+Q++ +QQ QQ S +L + T +S I + P
Sbjct: 1766 KIEATQKLEQVKNEQQ----QQQQQQFGSQHLLVQSGSDTPSSGIQSPLTP--------- 1812
Query: 145 MPASVVGQRPTIAMVTAINSQKAVLSTDVQNTPVNLQTSSKVTGPGA-----EAVQIVAK 199
Q M A + K + + +TP + + P A +I +
Sbjct: 1813 -------QPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQ 1865
Query: 200 NTVTLQVQATPPQP-IKVP---QFIPPPRLTPRPNFLPQVRPKPVAQNNIPIAPAPPPML 255
++++ + PP P + P PP + P + RP PV + A P
Sbjct: 1866 DSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVEN 1925
Query: 256 AAP-QLIQRPVMLTKFTPTTLPTSQNSIHPVRVVNGQTATIAKTFPMAQLTSIVIATPGT 314
P + RP+ + + T+ N PVR + + T + T + T
Sbjct: 1926 CTPLSSVSRPLQMNE-------TTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTD-- 1976
Query: 315 RLAGPQTVQLSK-PSLEKQTVK 335
P+++ LS+ P + +QT K
Sbjct: 1977 --QFPKSLGLSRSPVVSEQTAK 1996
Score = 31.2 bits (69), Expect = 3.0
Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 9/121 (7%)
Query: 41 QAKITALSEKQKRVVEQLRKNLIVKQEQPDKFQIQPLPQSENKLQTAQQQPLQQLQQQQQ 100
Q+ +++S Q+ ++ Q +E+P + QPL LQ Q Q+ QQQ+Q
Sbjct: 3019 QSGTSSMSGPQQLMIPQTLAQQ--NRERPLLLEEQPL-----LLQDLLDQERQEQQQQRQ 3071
Query: 101 YHHHHAQQSAAASPNL--TASQKTVTTASMITTKTLPLVLKAATATMPASVVGQRPTIAM 158
Q+S PN+ A + A M+ K + V+ MP V+ + P +
Sbjct: 3072 MQAMIRQRSEPFFPNIDFDAITDPIMKAKMVALKGINKVMAQNNLGMPPMVMSRFPFMGQ 3131
Query: 159 V 159
V
Sbjct: 3132 V 3132
>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform b
[Homo sapiens]
Length = 1524
Score = 57.4 bits (137), Expect = 4e-08
Identities = 21/46 (45%), Positives = 30/46 (65%), Gaps = 3/46 (6%)
Query: 445 CSVCRKSGQ---LLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRCQ 487
C +CRK G +++CD C R +H C+ P LKT+P+G W CP C+
Sbjct: 1119 CKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECR 1164
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.125 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,293,012
Number of Sequences: 37866
Number of extensions: 1405587
Number of successful extensions: 15144
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 241
Number of HSP's successfully gapped in prelim test: 742
Number of HSP's that attempted gapping in prelim test: 9627
Number of HSP's gapped (non-prelim): 4370
length of query: 634
length of database: 18,247,518
effective HSP length: 108
effective length of query: 526
effective length of database: 14,157,990
effective search space: 7447102740
effective search space used: 7447102740
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.