Search of human proteins with 15618997

Search of human proteins with 15618997

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15618997 glutathione peroxidase 7 [Homo sapiens]
         (187 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|15618997 glutathione peroxidase 7 [Homo sapiens]                   382   e-107
gi|192455698 glutathione peroxidase 8 [Homo sapiens]                  206   1e-53
gi|90903240 glutathione peroxidase 4 isoform C precursor [Homo s...   116   1e-26
gi|75709200 glutathione peroxidase 4 isoform A precursor [Homo s...   116   1e-26
gi|90903238 glutathione peroxidase 4 isoform B precursor [Homo s...   108   4e-24
gi|41406084 glutathione peroxidase 1 isoform 1 [Homo sapiens]          99   2e-21
gi|4557629 glutathione peroxidase 5 isoform 1 precursor [Homo sa...    92   3e-19
gi|32967607 glutathione peroxidase 2 [Homo sapiens]                    86   1e-17
gi|6006001 glutathione peroxidase 3 precursor [Homo sapiens]           82   4e-16
gi|33186887 glutathione peroxidase 6 [Homo sapiens]                    72   2e-13
gi|41406082 glutathione peroxidase 1 isoform 2 [Homo sapiens]          64   8e-11
gi|6715602 glutathione peroxidase 5 isoform 2 precursor [Homo sa...    33   0.11 
gi|130980075 centromere protein J [Homo sapiens]                       30   1.2  
gi|7661824 cornichon homolog 4 [Homo sapiens]                          29   2.7  
gi|31083028 CCR4 carbon catabolite repression 4-like [Homo sapiens]    28   4.6  
gi|239752518 PREDICTED: similar to leucine rich repeat containin...    27   7.9  
gi|55743114 leucine rich repeat containing 49 [Homo sapiens]           27   7.9  

>gi|15618997 glutathione peroxidase 7 [Homo sapiens]
          Length = 187

 Score =  382 bits (982), Expect = e-107
 Identities = 187/187 (100%), Positives = 187/187 (100%)

Query: 1   MVAATVAAAWLLLWAAACAQQEQDFYDFKAVNIRGKLVSLEKYRGSVSLVVNVASECGFT 60
           MVAATVAAAWLLLWAAACAQQEQDFYDFKAVNIRGKLVSLEKYRGSVSLVVNVASECGFT
Sbjct: 1   MVAATVAAAWLLLWAAACAQQEQDFYDFKAVNIRGKLVSLEKYRGSVSLVVNVASECGFT 60

Query: 61  DQHYRALQQLQRDLGPHHFNVLAFPCNQFGQQEPDSNKEIESFARRTYSVSFPMFSKIAV 120
           DQHYRALQQLQRDLGPHHFNVLAFPCNQFGQQEPDSNKEIESFARRTYSVSFPMFSKIAV
Sbjct: 61  DQHYRALQQLQRDLGPHHFNVLAFPCNQFGQQEPDSNKEIESFARRTYSVSFPMFSKIAV 120

Query: 121 TGTGAHPAFKYLAQTSGKEPTWNFWKYLVAPDGKVVGAWDPTVSVEEVRPQITALVRKLI 180
           TGTGAHPAFKYLAQTSGKEPTWNFWKYLVAPDGKVVGAWDPTVSVEEVRPQITALVRKLI
Sbjct: 121 TGTGAHPAFKYLAQTSGKEPTWNFWKYLVAPDGKVVGAWDPTVSVEEVRPQITALVRKLI 180

Query: 181 LLKREDL 187
           LLKREDL
Sbjct: 181 LLKREDL 187


>gi|192455698 glutathione peroxidase 8 [Homo sapiens]
          Length = 209

 Score =  206 bits (523), Expect = 1e-53
 Identities = 92/163 (56%), Positives = 124/163 (76%)

Query: 25  FYDFKAVNIRGKLVSLEKYRGSVSLVVNVASECGFTDQHYRALQQLQRDLGPHHFNVLAF 84
           FY F+  + +G+ VSLEKY+G VSLVVNVAS+C  TD++Y  L++L ++ GP HF+VLAF
Sbjct: 47  FYAFEVKDAKGRTVSLEKYKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVLAF 106

Query: 85  PCNQFGQQEPDSNKEIESFARRTYSVSFPMFSKIAVTGTGAHPAFKYLAQTSGKEPTWNF 144
           PCNQFG+ EP  +KE+ESFAR+ Y V+FP+F KI + G+   PAF++L  +S KEP WNF
Sbjct: 107 PCNQFGESEPRPSKEVESFARKNYGVTFPIFHKIKILGSEGEPAFRFLVDSSKKEPRWNF 166

Query: 145 WKYLVAPDGKVVGAWDPTVSVEEVRPQITALVRKLILLKREDL 187
           WKYLV P+G+VV  W P   +E +RP I ALVR++I+ K+EDL
Sbjct: 167 WKYLVNPEGQVVKFWKPEEPIEVIRPDIAALVRQVIIKKKEDL 209


>gi|90903240 glutathione peroxidase 4 isoform C precursor [Homo
           sapiens]
          Length = 234

 Score =  116 bits (290), Expect = 1e-26
 Identities = 65/145 (44%), Positives = 88/145 (60%), Gaps = 7/145 (4%)

Query: 23  QDFYDFKAVNIRGKLVSLEKYRGSVSLVVNVASECGFTDQHYRALQQLQRDLGPHHFNVL 82
           +  ++F A +I G +V+L+KYRG V +V NVAS+ G T+ +Y  L  L          +L
Sbjct: 76  RSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRIL 135

Query: 83  AFPCNQFGQQEPDSNKEIESFARRTYSVSFPMFSKIAVTGTGAHPAFKYL-AQTSGK--- 138
           AFPCNQFG+QEP SN+EI+ FA   Y+V F MFSKI V G  AHP +K++  Q  GK   
Sbjct: 136 AFPCNQFGKQEPGSNEEIKEFA-AGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGIL 194

Query: 139 --EPTWNFWKYLVAPDGKVVGAWDP 161
                WNF K+L+  +G VV  + P
Sbjct: 195 GNAIKWNFTKFLIDKNGCVVKRYGP 219


>gi|75709200 glutathione peroxidase 4 isoform A precursor [Homo
           sapiens]
          Length = 197

 Score =  116 bits (290), Expect = 1e-26
 Identities = 65/145 (44%), Positives = 88/145 (60%), Gaps = 7/145 (4%)

Query: 23  QDFYDFKAVNIRGKLVSLEKYRGSVSLVVNVASECGFTDQHYRALQQLQRDLGPHHFNVL 82
           +  ++F A +I G +V+L+KYRG V +V NVAS+ G T+ +Y  L  L          +L
Sbjct: 39  RSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRIL 98

Query: 83  AFPCNQFGQQEPDSNKEIESFARRTYSVSFPMFSKIAVTGTGAHPAFKYL-AQTSGK--- 138
           AFPCNQFG+QEP SN+EI+ FA   Y+V F MFSKI V G  AHP +K++  Q  GK   
Sbjct: 99  AFPCNQFGKQEPGSNEEIKEFA-AGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGIL 157

Query: 139 --EPTWNFWKYLVAPDGKVVGAWDP 161
                WNF K+L+  +G VV  + P
Sbjct: 158 GNAIKWNFTKFLIDKNGCVVKRYGP 182


>gi|90903238 glutathione peroxidase 4 isoform B precursor [Homo
           sapiens]
          Length = 227

 Score =  108 bits (269), Expect = 4e-24
 Identities = 60/131 (45%), Positives = 80/131 (61%), Gaps = 7/131 (5%)

Query: 23  QDFYDFKAVNIRGKLVSLEKYRGSVSLVVNVASECGFTDQHYRALQQLQRDLGPHHFNVL 82
           +  ++F A +I G +V+L+KYRG V +V NVAS+ G T+ +Y  L  L          +L
Sbjct: 39  RSMHEFSAKDIDGHMVNLDKYRGFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRIL 98

Query: 83  AFPCNQFGQQEPDSNKEIESFARRTYSVSFPMFSKIAVTGTGAHPAFKYL-AQTSGK--- 138
           AFPCNQFG+QEP SN+EI+ FA   Y+V F MFSKI V G  AHP +K++  Q  GK   
Sbjct: 99  AFPCNQFGKQEPGSNEEIKEFA-AGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGIL 157

Query: 139 --EPTWNFWKY 147
                WNF K+
Sbjct: 158 GNAIKWNFTKF 168


>gi|41406084 glutathione peroxidase 1 isoform 1 [Homo sapiens]
          Length = 203

 Score = 99.0 bits (245), Expect = 2e-21
 Identities = 66/190 (34%), Positives = 87/190 (45%), Gaps = 29/190 (15%)

Query: 16  AACAQQEQDFYDFKAVNIRG-KLVSLEKYRGSVSLVVNVASECGFTDQHYRALQQLQRDL 74
           AA A   Q  Y F A  + G + VSL   RG V L+ NVAS  G T + Y  + +LQR L
Sbjct: 7   AAAAAAAQSVYAFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTVRDYTQMNELQRRL 66

Query: 75  GPHHFNVLAFPCNQFGQQEPDSNKEIESFARRT-----YSVSFPMFSKIAVTGTGAHPAF 129
           GP    VL FPCNQFG QE   N+EI +  +       +  +F +F K  V G GAHP F
Sbjct: 67  GPRGLVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGGFEPNFMLFEKCEVNGAGAHPLF 126

Query: 130 KYLAQ-----------------------TSGKEPTWNFWKYLVAPDGKVVGAWDPTVSVE 166
            +L +                           +  WNF K+LV PDG  +  +       
Sbjct: 127 AFLREALPAPSDDATALMTDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYSRRFQTI 186

Query: 167 EVRPQITALV 176
           ++ P I AL+
Sbjct: 187 DIEPDIEALL 196


>gi|4557629 glutathione peroxidase 5 isoform 1 precursor [Homo
           sapiens]
          Length = 221

 Score = 91.7 bits (226), Expect = 3e-19
 Identities = 63/187 (33%), Positives = 89/187 (47%), Gaps = 27/187 (14%)

Query: 18  CAQQEQD-FYDFKAVNI-RGKLVSLEKYRGSVSLVVNVASECGFTDQHYRALQQLQRDLG 75
           C + E+   YD++A+ + + + VS ++Y G   L VNVA+ CG T Q Y  L  LQ +L 
Sbjct: 32  CHKDEKGTIYDYEAIALNKNEYVSFKQYVGKHILFVNVATYCGLTAQ-YPELNALQEELK 90

Query: 76  PHHFNVLAFPCNQFGQQEPDSNKEIESFARRT-----YSVSFPMFSKIAVTGTGAHPAFK 130
           P+   VL FPCNQFG+QEP  NKEI    +       +  SF +F K  V G      F 
Sbjct: 91  PYGLVVLGFPCNQFGKQEPGDNKEILPGLKYVRPGGGFVPSFQLFEKGDVNGEKEQKVFS 150

Query: 131 YLAQT-------------------SGKEPTWNFWKYLVAPDGKVVGAWDPTVSVEEVRPQ 171
           +L  +                      +  WNF K+LV PDG  V  W    +V  V+  
Sbjct: 151 FLKHSCPHPSEILGTFKSISWDPVKVHDIRWNFEKFLVGPDGIPVMRWSHRATVSSVKTD 210

Query: 172 ITALVRK 178
           I A +++
Sbjct: 211 ILAYLKQ 217


>gi|32967607 glutathione peroxidase 2 [Homo sapiens]
          Length = 190

 Score = 86.3 bits (212), Expect = 1e-17
 Identities = 55/186 (29%), Positives = 80/186 (43%), Gaps = 29/186 (15%)

Query: 23  QDFYDFKAVNIRGKLVSLEKYRGSVSLVVNVASECGFTDQHYRALQQLQRDLGPHHFNVL 82
           + FYD  A+++ G+ V    +RG   L+ NVAS  G T + +  L +LQ    P    VL
Sbjct: 6   KSFYDLSAISLDGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRF-PRRLVVL 64

Query: 83  AFPCNQFGQQEPDSNKEIESFARRT-----YSVSFPMFSKIAVTGTGAHPAFKYL----- 132
            FPCNQFG QE   N+EI +  +       Y  +F +  K  V G   HP F YL     
Sbjct: 65  GFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLKDKLP 124

Query: 133 ------------------AQTSGKEPTWNFWKYLVAPDGKVVGAWDPTVSVEEVRPQITA 174
                             +     +  WNF K+L+ P+G+    +  T     + P I  
Sbjct: 125 YPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEPDIKR 184

Query: 175 LVRKLI 180
           L++  I
Sbjct: 185 LLKVAI 190


>gi|6006001 glutathione peroxidase 3 precursor [Homo sapiens]
          Length = 226

 Score = 81.6 bits (200), Expect = 4e-16
 Identities = 59/178 (33%), Positives = 83/178 (46%), Gaps = 26/178 (14%)

Query: 26  YDFKAVNIRGK-LVSLEKYRGSVSLVVNVASECGFTDQHYRALQQLQRDLGPHHFNVLAF 84
           Y++ A+ I G+  +  ++Y G   L VNVAS  G T Q Y  L  LQ +L P    +L F
Sbjct: 41  YEYGALTIDGEEYIPFKQYAGKYVLFVNVASYUGLTGQ-YIELNALQEELAPFGLVILGF 99

Query: 85  PCNQFGQQEPDSNKEIESFARRT-----YSVSFPMFSKIAVTGTGAHPAFKYLAQ----- 134
           PCNQFG+QEP  N EI    +       +  +F +F K  V G      + +L       
Sbjct: 100 PCNQFGKQEPGENSEILPTLKYVRPGGGFVPNFQLFEKGDVNGEKEQKFYTFLKNSCPPT 159

Query: 135 -----TSGK---EP------TWNFWKYLVAPDGKVVGAWDPTVSVEEVRPQITALVRK 178
                TS +   EP       WNF K+LV PDG  +  W    +V  V+  I + +R+
Sbjct: 160 SELLGTSDRLFWEPMKVHDIRWNFEKFLVGPDGIPIMRWHHRTTVSNVKMDILSYMRR 217


>gi|33186887 glutathione peroxidase 6 [Homo sapiens]
          Length = 221

 Score = 72.4 bits (176), Expect = 2e-13
 Identities = 56/178 (31%), Positives = 79/178 (44%), Gaps = 26/178 (14%)

Query: 26  YDFKAVNIRGK-LVSLEKYRGSVSLVVNVASECGFTDQHYRALQQLQRDLGPHHFNVLAF 84
           Y++ A+ + G+  +  +++ G   L VNVA+  G   Q Y  L  LQ +L      VLAF
Sbjct: 41  YEYGALTLNGEEYIQFKQFAGKHVLFVNVAAYUGLAAQ-YPELNALQEELKNFGVIVLAF 99

Query: 85  PCNQFGQQEPDSNKEIESFARRT-----YSVSFPMFSKIAVTGTGAHPAFKYLAQTSGK- 138
           PCNQFG+QEP +N EI    +       +  SF +F K  V G      F +L  +    
Sbjct: 100 PCNQFGKQEPGTNSEILLGLKYVCPGSGFVPSFQLFEKGDVNGEKEQKVFTFLKNSCPPT 159

Query: 139 ------------EP------TWNFWKYLVAPDGKVVGAWDPTVSVEEVRPQITALVRK 178
                       EP       WNF K+LV PDG  V  W     V  V+  I   +++
Sbjct: 160 SDLLGSSSQLFWEPMKVHDIRWNFEKFLVGPDGVPVMHWFHQAPVSTVKSDILEYLKQ 217


>gi|41406082 glutathione peroxidase 1 isoform 2 [Homo sapiens]
          Length = 98

 Score = 63.9 bits (154), Expect = 8e-11
 Identities = 38/78 (48%), Positives = 44/78 (56%), Gaps = 1/78 (1%)

Query: 16 AACAQQEQDFYDFKAVNIRG-KLVSLEKYRGSVSLVVNVASECGFTDQHYRALQQLQRDL 74
          AA A   Q  Y F A  + G + VSL   RG V L+ NVAS  G T + Y  + +LQR L
Sbjct: 7  AAAAAAAQSVYAFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTVRDYTQMNELQRRL 66

Query: 75 GPHHFNVLAFPCNQFGQQ 92
          GP    VL FPCNQFG Q
Sbjct: 67 GPRGLVVLGFPCNQFGHQ 84


>gi|6715602 glutathione peroxidase 5 isoform 2 precursor [Homo
          sapiens]
          Length = 100

 Score = 33.5 bits (75), Expect = 0.11
 Identities = 18/48 (37%), Positives = 30/48 (62%), Gaps = 2/48 (4%)

Query: 18 CAQQEQD-FYDFKAVNI-RGKLVSLEKYRGSVSLVVNVASECGFTDQH 63
          C + E+   YD++A+ + + + VS ++Y G   L VNVA+ CG T Q+
Sbjct: 32 CHKDEKGTIYDYEAIALNKNEYVSFKQYVGKHILFVNVATYCGLTAQY 79


>gi|130980075 centromere protein J [Homo sapiens]
          Length = 1338

 Score = 30.0 bits (66), Expect = 1.2
 Identities = 26/88 (29%), Positives = 36/88 (40%), Gaps = 12/88 (13%)

Query: 29   KAVNIRGKLVSLEKYRGSVSLVVNVASECGFTDQ---HYRALQQLQRDLGPHHFNVLAFP 85
            K V+  GK +++  + G V  V+         DQ   +Y A  Q      P    VL F 
Sbjct: 1179 KEVSADGKTITVTFFNGDVKQVM--------PDQRVIYYYAAAQTTHTTYPEGLEVLHFS 1230

Query: 86   CNQFGQQEPDSNKEIESFARRTYSVSFP 113
              Q  +  PD  KEI +F  +T    FP
Sbjct: 1231 SGQIEKHYPDGRKEI-TFPDQTVKNLFP 1257


>gi|7661824 cornichon homolog 4 [Homo sapiens]
          Length = 139

 Score = 28.9 bits (63), Expect = 2.7
 Identities = 10/22 (45%), Positives = 16/22 (72%), Gaps = 1/22 (4%)

Query: 141 TWNFWKYLVAPDGKVVGAWDPT 162
           TWN ++Y++ P G  +G +DPT
Sbjct: 79  TWNIYRYIMVPSGN-MGVFDPT 99


>gi|31083028 CCR4 carbon catabolite repression 4-like [Homo sapiens]
          Length = 431

 Score = 28.1 bits (61), Expect = 4.6
 Identities = 16/48 (33%), Positives = 23/48 (47%)

Query: 122 GTGAHPAFKYLAQTSGKEPTWNFWKYLVAPDGKVVGAWDPTVSVEEVR 169
           GTG    +  LA+T          +YLV+PD + +   DP   +EE R
Sbjct: 68  GTGTSRLYSALAKTLNSSAASQHPEYLVSPDPEHLEPIDPKELLEECR 115


>gi|239752518 PREDICTED: similar to leucine rich repeat containing
           50, partial [Homo sapiens]
          Length = 489

 Score = 27.3 bits (59), Expect = 7.9
 Identities = 13/63 (20%), Positives = 26/63 (41%)

Query: 78  HFNVLAFPCNQFGQQEPDSNKEIESFARRTYSVSFPMFSKIAVTGTGAHPAFKYLAQTSG 137
           HF++      +  Q +    + +        S   P +  I++ G      F+YL ++ G
Sbjct: 345 HFSMQKINGTEVTQNDMIMAERLFGILAHVASSELPQYRLISILGDARKKQFRYLLESKG 404

Query: 138 KEP 140
           K+P
Sbjct: 405 KKP 407


>gi|55743114 leucine rich repeat containing 49 [Homo sapiens]
          Length = 686

 Score = 27.3 bits (59), Expect = 7.9
 Identities = 13/63 (20%), Positives = 26/63 (41%)

Query: 78  HFNVLAFPCNQFGQQEPDSNKEIESFARRTYSVSFPMFSKIAVTGTGAHPAFKYLAQTSG 137
           HF++      +  Q +    + +        S   P +  I++ G      F+YL ++ G
Sbjct: 521 HFSMQKINGTEVTQNDMIMAERLFGILAHVASSELPQYRLISILGDARKKQFRYLLESKG 580

Query: 138 KEP 140
           K+P
Sbjct: 581 KKP 583


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.133    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,929,263
Number of Sequences: 37866
Number of extensions: 275985
Number of successful extensions: 555
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 524
Number of HSP's gapped (non-prelim): 18
length of query: 187
length of database: 18,247,518
effective HSP length: 96
effective length of query: 91
effective length of database: 14,612,382
effective search space: 1329726762
effective search space used: 1329726762
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.