Guide to the Human Genome
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Name: GPX4 Sequence: fasta or formatted (197aa) NCBI GI: 75709200
Description:

glutathione peroxidase 4 isoform A precursor

Referenced in:

Glutathione Pathways
Selenium Proteins

Other entries for this name:
alt prot [227aa] glutathione peroxidase 4 isoform B precursor
alt prot [234aa] glutathione peroxidase 4 isoform C precursor
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.1         16           2
 C cysteine            4.6          9           1
 D aspartate           5.6         11           2
 E glutamate           5.1         10           2
 F phenylalanine       5.1         10           1
 G glycine             8.6         17           1
 H histidine           2.5          5           1
 I isoleucine          5.1         10           1
 K lysine              8.6         17           1
 L leucine             9.1         18           2
 M methionine          3.6          7           1
 N asparagine          5.1         10           1
 P proline             4.6          9           1
 Q glutamine           2.5          5           1
 R arginine            4.6          9           1
 S serine              3.6          7           1
 T threonine           2.5          5           1
 U selenocysteine      0.5          1           1
 V valine              5.6         11           2
 W tryptophan          2.0          4           1
 Y tyrosine            3.0          6           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   glutathione peroxidase 4 isoform A precursor 
GPX4                  0.862   glutathione peroxidase 4 isoform C precursor 
GPX4                  0.844   glutathione peroxidase 4 isoform B precursor 
GPX7                  0.233   glutathione peroxidase 7 
GPX8                  0.212   glutathione peroxidase 8 
GPX1                  0.194   glutathione peroxidase 1 isoform 1 
GPX2                  0.171   glutathione peroxidase 2 
GPX3                  0.151   glutathione peroxidase 3 precursor 
GPX5                  0.128   glutathione peroxidase 5 isoform 1 precursor 
GPX6                  0.128   glutathione peroxidase 6 
GPX1                  0.095   glutathione peroxidase 1 isoform 2 
KLHDC3                0.008   kelch domain containing 3 
WDR61                 0.005   WD repeat domain 61 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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