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Search of human proteins with 156119627
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156119627 potassium inwardly-rectifying channel J13 [Homo
sapiens]
(360 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156119627 potassium inwardly-rectifying channel J13 [Homo sap... 730 0.0
gi|25121966 potassium inwardly-rectifying channel, subfamily J, ... 255 4e-68
gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapi... 237 1e-62
gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapi... 237 1e-62
gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapi... 237 1e-62
gi|24497471 potassium inwardly-rectifying channel J1 isoform b [... 219 4e-57
gi|24497467 potassium inwardly-rectifying channel J1 isoform b [... 219 4e-57
gi|4504837 potassium inwardly-rectifying channel J1 isoform a [H... 219 4e-57
gi|148539892 potassium inwardly-rectifying channel J1 isoform b ... 219 4e-57
gi|24497473 potassium inwardly-rectifying channel J1 isoform b [... 219 4e-57
gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens] 197 9e-51
gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens] 197 9e-51
gi|25777635 potassium inwardly-rectifying channel J14 [Homo sapi... 197 9e-51
gi|23110982 potassium inwardly-rectifying channel, subfamily J, ... 189 3e-48
gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis... 187 1e-47
gi|25121970 potassium inwardly-rectifying channel subfamily J9 [... 187 2e-47
gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens] 183 2e-46
gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens] 182 3e-46
gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens] 179 4e-45
gi|239757993 PREDICTED: similar to inward rectifying K+ channel ... 178 8e-45
gi|239757991 PREDICTED: similar to inward rectifying K+ channel ... 178 8e-45
gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo ... 178 8e-45
gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens] 176 4e-44
gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens] 176 4e-44
gi|62388888 potassium inwardly-rectifying channel J11 [Homo sapi... 161 1e-39
gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens] 160 2e-39
gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens] 156 2e-38
gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapi... 156 2e-38
gi|25777628 potassium inwardly-rectifying channel J16 [Homo sapi... 156 2e-38
gi|27886667 potassium voltage-gated channel, subfamily H, member... 34 0.18
>gi|156119627 potassium inwardly-rectifying channel J13 [Homo
sapiens]
Length = 360
Score = 730 bits (1885), Expect = 0.0
Identities = 360/360 (100%), Positives = 360/360 (100%)
Query: 1 MDSSNCKVIAPLLSQRYRRMVTKDGHSTLQMDGAQRGLAYLRDAWGILMDMRWRWMMLVF 60
MDSSNCKVIAPLLSQRYRRMVTKDGHSTLQMDGAQRGLAYLRDAWGILMDMRWRWMMLVF
Sbjct: 1 MDSSNCKVIAPLLSQRYRRMVTKDGHSTLQMDGAQRGLAYLRDAWGILMDMRWRWMMLVF 60
Query: 61 SASFVVHWLVFAVLWYVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTI 120
SASFVVHWLVFAVLWYVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTI
Sbjct: 61 SASFVVHWLVFAVLWYVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTI 120
Query: 121 GYGTMFPSGDCPSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAH 180
GYGTMFPSGDCPSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAH
Sbjct: 121 GYGTMFPSGDCPSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAH 180
Query: 181 MDGKPNLIFQVANTRPSPLTSVRVSAVLYQERENGKLYQTSVDFHLDGISSDECPFFIFP 240
MDGKPNLIFQVANTRPSPLTSVRVSAVLYQERENGKLYQTSVDFHLDGISSDECPFFIFP
Sbjct: 181 MDGKPNLIFQVANTRPSPLTSVRVSAVLYQERENGKLYQTSVDFHLDGISSDECPFFIFP 240
Query: 241 LTYYHSITPSSPLATLLQHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFA 300
LTYYHSITPSSPLATLLQHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFA
Sbjct: 241 LTYYHSITPSSPLATLLQHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFA 300
Query: 301 SLLTRGSKGEYQIKMENFDKTVPEFPTPLVSKSPNRTDLDIHINGQSIDNFQISETGLTE 360
SLLTRGSKGEYQIKMENFDKTVPEFPTPLVSKSPNRTDLDIHINGQSIDNFQISETGLTE
Sbjct: 301 SLLTRGSKGEYQIKMENFDKTVPEFPTPLVSKSPNRTDLDIHINGQSIDNFQISETGLTE 360
>gi|25121966 potassium inwardly-rectifying channel, subfamily J,
member 10 [Homo sapiens]
Length = 379
Score = 255 bits (652), Expect = 4e-68
Identities = 144/314 (45%), Positives = 195/314 (62%), Gaps = 12/314 (3%)
Query: 16 RYRRMVTKDGHSTLQMDG-AQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVL 74
R RR++TKDG S ++M+ A + YL+D W +DM+WR+ +L+FSA+F W +F V+
Sbjct: 26 RRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVV 85
Query: 75 WYVLAEMNGDL-ELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPS 133
WY++A +GDL ELD PP NHT CV + + T AF FSLE+Q TIGYG + S +CP
Sbjct: 86 WYLVAVAHGDLLELD---PPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPL 142
Query: 134 AIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVAN 193
AI LL Q++L +LE FITG F+AKIARPK RA +IRF+ AVVA +GKP L+ +VAN
Sbjct: 143 AIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVAN 202
Query: 194 TRPSPLTSVRVSAVLYQ-----ERENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHSIT 248
R S L +V+ L Q E EN +L Q +V F +D ++ + PF I PLT+YH +
Sbjct: 203 MRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVD--TASDSPFLILPLTFYHVVD 260
Query: 249 PSSPLATLLQHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSK 308
+SPL L FELV+ LS E T CQ RTSYLP EI+ + F ++ +
Sbjct: 261 ETSPLKDLPLRSGEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSAS 320
Query: 309 GEYQIKMENFDKTV 322
G+Y FD+ V
Sbjct: 321 GKYIADFSLFDQVV 334
>gi|21361127 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 237 bits (604), Expect = 1e-62
Identities = 135/326 (41%), Positives = 194/326 (59%), Gaps = 20/326 (6%)
Query: 19 RMVTKDGHSTLQMDGAQR-GLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYV 77
R+++K GHS +++D L YL+D W ++DM+WR+ + +F+A+FV+ W +F V++Y
Sbjct: 28 RVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYA 87
Query: 78 LAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIAL 137
+A ++GDLE P NHT C+ + S T AF FSLE+Q TIGYG + +CP AI L
Sbjct: 88 IAFIHGDLEPGE--PISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
Query: 138 LAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTRPS 197
L Q+++ ++E FITG F+AKIARPK RA +I+F+ AV+ +GK L+ QVAN R S
Sbjct: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
Query: 198 PLTSVRVSAVLYQ-----ERENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHSITPSSP 252
L ++S L Q E E L Q +V FH+D SS E PF I P+T+YH + +SP
Sbjct: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD--SSSESPFLILPMTFYHVLDETSP 263
Query: 253 LATLL-QHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGEY 311
L L Q+ FELVV L+A E T +CQ RTSY+P EI F +++ G+Y
Sbjct: 264 LRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKY 323
Query: 312 QIKMENFDKTVPEFPTPLVSKSPNRT 337
F++ + KSP+ T
Sbjct: 324 VADFSQFEQ---------IRKSPDCT 340
>gi|25777640 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 237 bits (604), Expect = 1e-62
Identities = 135/326 (41%), Positives = 194/326 (59%), Gaps = 20/326 (6%)
Query: 19 RMVTKDGHSTLQMDGAQR-GLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYV 77
R+++K GHS +++D L YL+D W ++DM+WR+ + +F+A+FV+ W +F V++Y
Sbjct: 28 RVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYA 87
Query: 78 LAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIAL 137
+A ++GDLE P NHT C+ + S T AF FSLE+Q TIGYG + +CP AI L
Sbjct: 88 IAFIHGDLEPGE--PISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
Query: 138 LAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTRPS 197
L Q+++ ++E FITG F+AKIARPK RA +I+F+ AV+ +GK L+ QVAN R S
Sbjct: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
Query: 198 PLTSVRVSAVLYQ-----ERENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHSITPSSP 252
L ++S L Q E E L Q +V FH+D SS E PF I P+T+YH + +SP
Sbjct: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD--SSSESPFLILPMTFYHVLDETSP 263
Query: 253 LATLL-QHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGEY 311
L L Q+ FELVV L+A E T +CQ RTSY+P EI F +++ G+Y
Sbjct: 264 LRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKY 323
Query: 312 QIKMENFDKTVPEFPTPLVSKSPNRT 337
F++ + KSP+ T
Sbjct: 324 VADFSQFEQ---------IRKSPDCT 340
>gi|25777638 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 237 bits (604), Expect = 1e-62
Identities = 135/326 (41%), Positives = 194/326 (59%), Gaps = 20/326 (6%)
Query: 19 RMVTKDGHSTLQMDGAQR-GLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYV 77
R+++K GHS +++D L YL+D W ++DM+WR+ + +F+A+FV+ W +F V++Y
Sbjct: 28 RVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYA 87
Query: 78 LAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIAL 137
+A ++GDLE P NHT C+ + S T AF FSLE+Q TIGYG + +CP AI L
Sbjct: 88 IAFIHGDLEPGE--PISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHAIFL 145
Query: 138 LAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTRPS 197
L Q+++ ++E FITG F+AKIARPK RA +I+F+ AV+ +GK L+ QVAN R S
Sbjct: 146 LVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANMRKS 205
Query: 198 PLTSVRVSAVLYQ-----ERENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHSITPSSP 252
L ++S L Q E E L Q +V FH+D SS E PF I P+T+YH + +SP
Sbjct: 206 LLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVD--SSSESPFLILPMTFYHVLDETSP 263
Query: 253 LATLL-QHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGEY 311
L L Q+ FELVV L+A E T +CQ RTSY+P EI F +++ G+Y
Sbjct: 264 LRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGKY 323
Query: 312 QIKMENFDKTVPEFPTPLVSKSPNRT 337
F++ + KSP+ T
Sbjct: 324 VADFSQFEQ---------IRKSPDCT 340
>gi|24497471 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 219 bits (557), Expect = 4e-57
Identities = 138/361 (38%), Positives = 203/361 (56%), Gaps = 23/361 (6%)
Query: 14 SQRYRRMVTKDGHSTLQMDG--AQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVF 71
S++ R+V+KDG ++ AQ + D W ++D++WR+ M +F +F+ W F
Sbjct: 17 SRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFF 76
Query: 72 AVLWYVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDC 131
+LWY +A ++ DL H P NHT CV+ I T+AF FSLETQ+TIGYG + C
Sbjct: 77 GLLWYAVAYIHKDLPEFH--PSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 134
Query: 132 PSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQV 191
+AI LL Q +LG+++ +F+ GA +AKI+RPK RA +I F+ AV++ GK L+ +V
Sbjct: 135 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 194
Query: 192 ANTRPSPLTSVRVSAVLYQ-----ERENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHS 246
AN R S L + L + E E L Q +++F +D + +E FFI PLT YH
Sbjct: 195 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVD--AGNENLFFISPLTIYHV 252
Query: 247 ITPSSPL-----ATLLQHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFAS 301
I +SP TLLQ + FELVVFL E T CQ RTSY+P E++ + FA
Sbjct: 253 IDHNSPFFHMAAETLLQQD----FELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAP 308
Query: 302 LLTRGSKGEYQIKMENFDKTVPEFPTPLVSKS-PNRTDLDIHI-NGQSIDNFQISETGLT 359
++++ +G+Y++ NF KTV E TP + N D+ + G NF +SE T
Sbjct: 309 IVSKTKEGKYRVDFHNFSKTV-EVETPHCAMCLYNEKDVRARMKRGYDNPNFILSEVNET 367
Query: 360 E 360
+
Sbjct: 368 D 368
>gi|24497467 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 219 bits (557), Expect = 4e-57
Identities = 138/361 (38%), Positives = 203/361 (56%), Gaps = 23/361 (6%)
Query: 14 SQRYRRMVTKDGHSTLQMDG--AQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVF 71
S++ R+V+KDG ++ AQ + D W ++D++WR+ M +F +F+ W F
Sbjct: 17 SRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFF 76
Query: 72 AVLWYVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDC 131
+LWY +A ++ DL H P NHT CV+ I T+AF FSLETQ+TIGYG + C
Sbjct: 77 GLLWYAVAYIHKDLPEFH--PSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 134
Query: 132 PSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQV 191
+AI LL Q +LG+++ +F+ GA +AKI+RPK RA +I F+ AV++ GK L+ +V
Sbjct: 135 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 194
Query: 192 ANTRPSPLTSVRVSAVLYQ-----ERENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHS 246
AN R S L + L + E E L Q +++F +D + +E FFI PLT YH
Sbjct: 195 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVD--AGNENLFFISPLTIYHV 252
Query: 247 ITPSSPL-----ATLLQHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFAS 301
I +SP TLLQ + FELVVFL E T CQ RTSY+P E++ + FA
Sbjct: 253 IDHNSPFFHMAAETLLQQD----FELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAP 308
Query: 302 LLTRGSKGEYQIKMENFDKTVPEFPTPLVSKS-PNRTDLDIHI-NGQSIDNFQISETGLT 359
++++ +G+Y++ NF KTV E TP + N D+ + G NF +SE T
Sbjct: 309 IVSKTKEGKYRVDFHNFSKTV-EVETPHCAMCLYNEKDVRARMKRGYDNPNFILSEVNET 367
Query: 360 E 360
+
Sbjct: 368 D 368
>gi|4504837 potassium inwardly-rectifying channel J1 isoform a [Homo
sapiens]
Length = 391
Score = 219 bits (557), Expect = 4e-57
Identities = 138/361 (38%), Positives = 203/361 (56%), Gaps = 23/361 (6%)
Query: 14 SQRYRRMVTKDGHSTLQMDG--AQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVF 71
S++ R+V+KDG ++ AQ + D W ++D++WR+ M +F +F+ W F
Sbjct: 36 SRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFF 95
Query: 72 AVLWYVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDC 131
+LWY +A ++ DL H P NHT CV+ I T+AF FSLETQ+TIGYG + C
Sbjct: 96 GLLWYAVAYIHKDLPEFH--PSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 153
Query: 132 PSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQV 191
+AI LL Q +LG+++ +F+ GA +AKI+RPK RA +I F+ AV++ GK L+ +V
Sbjct: 154 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 213
Query: 192 ANTRPSPLTSVRVSAVLYQ-----ERENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHS 246
AN R S L + L + E E L Q +++F +D + +E FFI PLT YH
Sbjct: 214 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVD--AGNENLFFISPLTIYHV 271
Query: 247 ITPSSPL-----ATLLQHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFAS 301
I +SP TLLQ + FELVVFL E T CQ RTSY+P E++ + FA
Sbjct: 272 IDHNSPFFHMAAETLLQQD----FELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAP 327
Query: 302 LLTRGSKGEYQIKMENFDKTVPEFPTPLVSKS-PNRTDLDIHI-NGQSIDNFQISETGLT 359
++++ +G+Y++ NF KTV E TP + N D+ + G NF +SE T
Sbjct: 328 IVSKTKEGKYRVDFHNFSKTV-EVETPHCAMCLYNEKDVRARMKRGYDNPNFILSEVNET 386
Query: 360 E 360
+
Sbjct: 387 D 387
>gi|148539892 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 219 bits (557), Expect = 4e-57
Identities = 138/361 (38%), Positives = 203/361 (56%), Gaps = 23/361 (6%)
Query: 14 SQRYRRMVTKDGHSTLQMDG--AQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVF 71
S++ R+V+KDG ++ AQ + D W ++D++WR+ M +F +F+ W F
Sbjct: 17 SRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFF 76
Query: 72 AVLWYVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDC 131
+LWY +A ++ DL H P NHT CV+ I T+AF FSLETQ+TIGYG + C
Sbjct: 77 GLLWYAVAYIHKDLPEFH--PSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 134
Query: 132 PSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQV 191
+AI LL Q +LG+++ +F+ GA +AKI+RPK RA +I F+ AV++ GK L+ +V
Sbjct: 135 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 194
Query: 192 ANTRPSPLTSVRVSAVLYQ-----ERENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHS 246
AN R S L + L + E E L Q +++F +D + +E FFI PLT YH
Sbjct: 195 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVD--AGNENLFFISPLTIYHV 252
Query: 247 ITPSSPL-----ATLLQHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFAS 301
I +SP TLLQ + FELVVFL E T CQ RTSY+P E++ + FA
Sbjct: 253 IDHNSPFFHMAAETLLQQD----FELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAP 308
Query: 302 LLTRGSKGEYQIKMENFDKTVPEFPTPLVSKS-PNRTDLDIHI-NGQSIDNFQISETGLT 359
++++ +G+Y++ NF KTV E TP + N D+ + G NF +SE T
Sbjct: 309 IVSKTKEGKYRVDFHNFSKTV-EVETPHCAMCLYNEKDVRARMKRGYDNPNFILSEVNET 367
Query: 360 E 360
+
Sbjct: 368 D 368
>gi|24497473 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 219 bits (557), Expect = 4e-57
Identities = 138/361 (38%), Positives = 203/361 (56%), Gaps = 23/361 (6%)
Query: 14 SQRYRRMVTKDGHSTLQMDG--AQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVF 71
S++ R+V+KDG ++ AQ + D W ++D++WR+ M +F +F+ W F
Sbjct: 17 SRQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFF 76
Query: 72 AVLWYVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDC 131
+LWY +A ++ DL H P NHT CV+ I T+AF FSLETQ+TIGYG + C
Sbjct: 77 GLLWYAVAYIHKDLPEFH--PSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQC 134
Query: 132 PSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQV 191
+AI LL Q +LG+++ +F+ GA +AKI+RPK RA +I F+ AV++ GK L+ +V
Sbjct: 135 ATAIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRV 194
Query: 192 ANTRPSPLTSVRVSAVLYQ-----ERENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHS 246
AN R S L + L + E E L Q +++F +D + +E FFI PLT YH
Sbjct: 195 ANLRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVD--AGNENLFFISPLTIYHV 252
Query: 247 ITPSSPL-----ATLLQHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFAS 301
I +SP TLLQ + FELVVFL E T CQ RTSY+P E++ + FA
Sbjct: 253 IDHNSPFFHMAAETLLQQD----FELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAP 308
Query: 302 LLTRGSKGEYQIKMENFDKTVPEFPTPLVSKS-PNRTDLDIHI-NGQSIDNFQISETGLT 359
++++ +G+Y++ NF KTV E TP + N D+ + G NF +SE T
Sbjct: 309 IVSKTKEGKYRVDFHNFSKTV-EVETPHCAMCLYNEKDVRARMKRGYDNPNFILSEVNET 367
Query: 360 E 360
+
Sbjct: 368 D 368
>gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens]
Length = 427
Score = 197 bits (502), Expect = 9e-51
Identities = 119/318 (37%), Positives = 181/318 (56%), Gaps = 11/318 (3%)
Query: 19 RMVTKDGHSTLQ-MDGAQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYV 77
R V KDGH +Q ++ ++G YL D + +D+RWRWM+++F +FV+ WL F ++++
Sbjct: 46 RFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWL 105
Query: 78 LAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIAL 137
+A ++GDL DA E CV + SFTAAF FS+ETQ TIGYG + +CP A+ +
Sbjct: 106 IALLHGDL----DASKEGKA-CVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFM 160
Query: 138 LAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTRPS 197
+ Q ++G +++AFI GA +AK+A+PK R ++ F+ AV+A DGK L+++V N R S
Sbjct: 161 VVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKS 220
Query: 198 PLTSVRVSAVLYQER---ENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHSITPSSPLA 254
L V A L + R E + +D ++ S + F + P+T H I SPL
Sbjct: 221 HLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLY 280
Query: 255 TLLQHE-NPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGEYQI 313
L + + + + FE+VV L M E T Q R+SYL +EI+ H + +L K Y++
Sbjct: 281 DLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFE-EKHYYKV 339
Query: 314 KMENFDKTVPEFPTPLVS 331
F KT TPL S
Sbjct: 340 DYSRFHKTYEVPNTPLCS 357
>gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens]
Length = 436
Score = 197 bits (502), Expect = 9e-51
Identities = 124/327 (37%), Positives = 185/327 (56%), Gaps = 17/327 (5%)
Query: 13 LSQRYRRMVTKDGHSTLQ-MDGAQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVF 71
+ +R R V KDGH ++ ++ +G YL D + +D+RWRWM L+FS SF+ WL+F
Sbjct: 45 VGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLF 104
Query: 72 AVLWYVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDC 131
+ ++++A ++GDL A P C ++ SF AAF F+LETQ +IGYG + +C
Sbjct: 105 GLAFWLIASLHGDL-----AAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEEC 159
Query: 132 PSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQV 191
P+A+A + +Q + G +L+AF+ GA +AK+A+PK R ++ F++ AVVA D + L+++V
Sbjct: 160 PAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRV 219
Query: 192 ANTRPSPLTSVRVSAVLYQER-----ENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHS 246
N R S L V A L Q R E L VD DG + F + P+T H
Sbjct: 220 GNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDG--GTDRIFLVSPITIVHE 277
Query: 247 ITPSSPLATLLQHE-NPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLL-T 304
I +SPL L + E + FELVV L M E T Q R+SYLP E++ H F +L
Sbjct: 278 IDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQ 337
Query: 305 RGSKGEYQIKMENFDKTVPEFPTPLVS 331
RGS +Y++ +F +T TP+ S
Sbjct: 338 RGS--QYEVDYRHFHRTYEVPGTPVCS 362
>gi|25777635 potassium inwardly-rectifying channel J14 [Homo
sapiens]
Length = 436
Score = 197 bits (502), Expect = 9e-51
Identities = 124/327 (37%), Positives = 185/327 (56%), Gaps = 17/327 (5%)
Query: 13 LSQRYRRMVTKDGHSTLQ-MDGAQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVF 71
+ +R R V KDGH ++ ++ +G YL D + +D+RWRWM L+FS SF+ WL+F
Sbjct: 45 VGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLF 104
Query: 72 AVLWYVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDC 131
+ ++++A ++GDL A P C ++ SF AAF F+LETQ +IGYG + +C
Sbjct: 105 GLAFWLIASLHGDL-----AAPPPPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEEC 159
Query: 132 PSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQV 191
P+A+A + +Q + G +L+AF+ GA +AK+A+PK R ++ F++ AVVA D + L+++V
Sbjct: 160 PAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRV 219
Query: 192 ANTRPSPLTSVRVSAVLYQER-----ENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHS 246
N R S L V A L Q R E L VD DG + F + P+T H
Sbjct: 220 GNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDG--GTDRIFLVSPITIVHE 277
Query: 247 ITPSSPLATLLQHE-NPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLL-T 304
I +SPL L + E + FELVV L M E T Q R+SYLP E++ H F +L
Sbjct: 278 IDSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQ 337
Query: 305 RGSKGEYQIKMENFDKTVPEFPTPLVS 331
RGS +Y++ +F +T TP+ S
Sbjct: 338 RGS--QYEVDYRHFHRTYEVPGTPVCS 362
>gi|23110982 potassium inwardly-rectifying channel, subfamily J,
member 12 [Homo sapiens]
Length = 433
Score = 189 bits (481), Expect = 3e-48
Identities = 117/320 (36%), Positives = 178/320 (55%), Gaps = 13/320 (4%)
Query: 19 RMVTKDGHSTLQMDGA-QRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYV 77
R V K+G ++ ++ YL D + +D+RWR+M+L+FS +F+ WL+F ++++V
Sbjct: 45 RFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGIIFWV 104
Query: 78 LAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIAL 137
+A +GDLE A T CV + F AAF FS+ETQ TIGYG + +CP A+ +
Sbjct: 105 IAVAHGDLE---PAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFM 161
Query: 138 LAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTRPS 197
+ Q ++G ++++F+ GA +AK+ARPK RA ++ F+ AVVA DGK L+++V N R S
Sbjct: 162 VVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKS 221
Query: 198 PLTSVRVSAVLYQER--ENGK---LYQTSVDFHLDGISSDECPFFIFPLTYYHSITPSSP 252
+ V A L + R E G+ L Q +D D + F + P+T H I +SP
Sbjct: 222 HIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFD--KGLDRIFLVSPITILHEIDEASP 279
Query: 253 LATLLQHE-NPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGEY 311
L + + + FE+VV L M E T Q R+SYL +EI+ H F +L K +Y
Sbjct: 280 LFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFE-EKNQY 338
Query: 312 QIKMENFDKTVPEFPTPLVS 331
+I +F KT TP S
Sbjct: 339 KIDYSHFHKTYEVPSTPRCS 358
>gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis
susceptibility ion channel [Homo sapiens]
Length = 433
Score = 187 bits (475), Expect = 1e-47
Identities = 119/322 (36%), Positives = 178/322 (55%), Gaps = 17/322 (5%)
Query: 19 RMVTKDGHSTLQMDGA-QRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYV 77
R V K+G + ++ YL D + +D+RWR+M+L+FS +F+ WL+F V+++V
Sbjct: 45 RFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWV 104
Query: 78 LAEMNGDLELDHDAPPENH--TICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAI 135
+A +GDLE P E H T CV + F AAF FS+ETQ TIGYG + +C A+
Sbjct: 105 IAVAHGDLE-----PAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAV 159
Query: 136 ALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTR 195
++ Q ++G ++++F+ GA +AK+ARPK RA ++ F+ AVVA DGK L+++V N R
Sbjct: 160 FMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLR 219
Query: 196 PSPLTSVRVSAVLYQER--ENGK---LYQTSVDFHLDGISSDECPFFIFPLTYYHSITPS 250
S + V A L + R E G+ L Q +D D + F + P+T H I +
Sbjct: 220 KSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFD--KGLDRIFLVSPITILHEIDEA 277
Query: 251 SPLATLLQHE-NPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKG 309
SPL + + + FE+VV L M E T Q R+SYL +EI+ H F +L K
Sbjct: 278 SPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFE-EKN 336
Query: 310 EYQIKMENFDKTVPEFPTPLVS 331
+Y+I +F KT TP S
Sbjct: 337 QYKIDYSHFHKTYEVPSTPRCS 358
>gi|25121970 potassium inwardly-rectifying channel subfamily J9
[Homo sapiens]
Length = 393
Score = 187 bits (474), Expect = 2e-47
Identities = 114/320 (35%), Positives = 168/320 (52%), Gaps = 13/320 (4%)
Query: 18 RRMVTKDGHSTLQMDGAQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYV 77
+R V KDG +Q + YL D + L+D++WR +L F ++ + WL F +W++
Sbjct: 22 QRYVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWL 81
Query: 78 LAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIAL 137
+A GDLE D T CV + F AAF FS+ET+ TIGYG + CP I L
Sbjct: 82 IAYGRGDLEHLEDTA---WTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEGIVL 138
Query: 138 LAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTRPS 197
L +Q +LG M+ AF+ G KI++P RA ++ F+ AVV+ DG+ L+F+V + R S
Sbjct: 139 LLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDLRSS 198
Query: 198 PLTSVRVSAVLYQERENGK-----LYQTSVDFHLDGISSDECPFFIFPLTYYHSITPSSP 252
+ + A L + R+ + L+QT + D + D+ F + PL H I +SP
Sbjct: 199 HIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFD--TGDDRLFLVSPLVISHEIDAASP 256
Query: 253 LATLLQHE-NPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGEY 311
+ FE+VV L M E TG CQ R+SYL E++ H F S+LT G Y
Sbjct: 257 FWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTL-EDGFY 315
Query: 312 QIKMENFDKTVPEFPTPLVS 331
++ +F +T E PTP S
Sbjct: 316 EVDYASFHETF-EVPTPSCS 334
>gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens]
Length = 423
Score = 183 bits (464), Expect = 2e-46
Identities = 108/321 (33%), Positives = 174/321 (54%), Gaps = 9/321 (2%)
Query: 15 QRYRRMVTKDGHSTLQMDGAQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVL 74
++ +R V KDG + + YL D + L+D++WR+ +L+F + V WL F ++
Sbjct: 51 RKIQRYVRKDGKCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMI 110
Query: 75 WYVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSA 134
W+++A + GD+ DH P + T CV + F +AF FS+ET+ TIGYG + CP
Sbjct: 111 WWLIAYIRGDM--DHIEDP-SWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEG 167
Query: 135 IALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANT 194
I LL IQ +LG ++ AF+ G KI++PK RA ++ F+ AV++ DGK L+F+V +
Sbjct: 168 IILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDL 227
Query: 195 RPSPLTSVRVSAVLYQERENGK---LYQTSVDFHLDGISSDECPFFIFPLTYYHSITPSS 251
R S + + A L + ++ + + D ++ + D+ F + PL H I S
Sbjct: 228 RNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQS 287
Query: 252 PLATLLQHENP-SHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGE 310
P + + + P E+VV L M E TG CQ R+SY+ SEI+ + F +LT G
Sbjct: 288 PFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTL-EDGF 346
Query: 311 YQIKMENFDKTVPEFPTPLVS 331
Y++ +F +T E TP +S
Sbjct: 347 YEVDYNSFHETY-ETSTPSLS 366
>gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens]
Length = 419
Score = 182 bits (463), Expect = 3e-46
Identities = 107/310 (34%), Positives = 168/310 (54%), Gaps = 12/310 (3%)
Query: 18 RRMVTKDGHSTLQMDGAQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYV 77
+R + K G + Q YL D + L+D++WR+ +LVF+ + V WL F +W++
Sbjct: 51 QRYMEKSGKCNVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWL 110
Query: 78 LAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAIAL 137
+A + GDL DH E CV+ ++ F +AF FS+ET+ TIGYG + CP I L
Sbjct: 111 IAYIRGDL--DHVGDQE-WIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIIL 167
Query: 138 LAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTRPS 197
L +Q +LG ++ AF+ G KI++PK RA ++ F++ AV++ D K L+F+V + R S
Sbjct: 168 LLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNS 227
Query: 198 PLTSVRVSAVLYQERENGK-----LYQTSVDFHLDGISSDECPFFIFPLTYYHSITPSSP 252
+ + A L + R+ + L QT ++ D + D+ F + PL H I SP
Sbjct: 228 HIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFD--TGDDRLFLVSPLIISHEINQKSP 285
Query: 253 LATLLQHE-NPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGEY 311
+ Q + + FE+VV L M E TG CQ R+SY+ +E++ H F +LT KG Y
Sbjct: 286 FWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTL-EKGFY 344
Query: 312 QIKMENFDKT 321
++ F T
Sbjct: 345 EVDYNTFHDT 354
>gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens]
Length = 501
Score = 179 bits (453), Expect = 4e-45
Identities = 105/319 (32%), Positives = 168/319 (52%), Gaps = 10/319 (3%)
Query: 15 QRYRRMVTKDGHSTLQMDG-AQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAV 73
++ +R V K+G +Q YL D + L+D++WRW + +F ++ V WL A
Sbjct: 41 KKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMAS 100
Query: 74 LWYVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPS 133
+W+V+A GDL H N+T CV + +F +AF F +ET+ TIGYG + + CP
Sbjct: 101 MWWVIAYTRGDLNKAHVG---NYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPE 157
Query: 134 AIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVAN 193
I L Q +LG +++AF+ G K+++PK RA ++ F++ AV++ DGK L+F+V N
Sbjct: 158 GIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGN 217
Query: 194 TRPSPLTSVRVSAVLYQERENGK---LYQTSVDFHLDGISSDECPFFIFPLTYYHSITPS 250
R S + S ++ L + R+ + L ++ + + + F + PLT H I
Sbjct: 218 LRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAK 277
Query: 251 SPLATLLQHE-NPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKG 309
SP L Q FE+VV L + E TG CQ RTSY E++ H F +++ +G
Sbjct: 278 SPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISL-EEG 336
Query: 310 EYQIKMENFDKTVPEFPTP 328
+++ F T E PTP
Sbjct: 337 FFKVDYSQFHATF-EVPTP 354
>gi|239757993 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 1 [Homo sapiens]
Length = 432
Score = 178 bits (451), Expect = 8e-45
Identities = 111/322 (34%), Positives = 173/322 (53%), Gaps = 14/322 (4%)
Query: 17 YRRMVTKDGHSTLQMDGA-QRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLW 75
+ R V K+G ++ ++ YL D + +D+RWR+M+L+FS +F+ WL+F V++
Sbjct: 43 HNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIF 102
Query: 76 YVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAI 135
+V+A +GDLE A T CV + F AAF FS++TQ TI YG + +CP A+
Sbjct: 103 WVIAVAHGDLE---PAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAV 159
Query: 136 ALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTR 195
++ Q ++G ++ +F+ GA +AK+ RPK RA ++ F+ AVVA DGK +++V N R
Sbjct: 160 FMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLR 219
Query: 196 PSPLTSVRVSAVLYQER-----ENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHSITPS 250
S + V A L + R E L Q +D D + F + P+T H I +
Sbjct: 220 KSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFD--KGLDHSFLVSPITILHEIDEA 277
Query: 251 SPLATLLQHE-NPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKG 309
SPL + + + FE+V+ L + E T Q R+SYL +EI+ H F +L K
Sbjct: 278 SPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVLF--EKN 335
Query: 310 EYQIKMENFDKTVPEFPTPLVS 331
+Y+I +F KT TP S
Sbjct: 336 QYKIDYLHFHKTYEVPSTPRCS 357
>gi|239757991 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 2 [Homo sapiens]
Length = 534
Score = 178 bits (451), Expect = 8e-45
Identities = 111/322 (34%), Positives = 173/322 (53%), Gaps = 14/322 (4%)
Query: 17 YRRMVTKDGHSTLQMDGA-QRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLW 75
+ R V K+G ++ ++ YL D + +D+RWR+M+L+FS +F+ WL+F V++
Sbjct: 145 HNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIF 204
Query: 76 YVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAI 135
+V+A +GDLE A T CV + F AAF FS++TQ TI YG + +CP A+
Sbjct: 205 WVIAVAHGDLE---PAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAV 261
Query: 136 ALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTR 195
++ Q ++G ++ +F+ GA +AK+ RPK RA ++ F+ AVVA DGK +++V N R
Sbjct: 262 FMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLR 321
Query: 196 PSPLTSVRVSAVLYQER-----ENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHSITPS 250
S + V A L + R E L Q +D D + F + P+T H I +
Sbjct: 322 KSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFD--KGLDHSFLVSPITILHEIDEA 379
Query: 251 SPLATLLQHE-NPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKG 309
SPL + + + FE+V+ L + E T Q R+SYL +EI+ H F +L K
Sbjct: 380 SPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVLF--EKN 437
Query: 310 EYQIKMENFDKTVPEFPTPLVS 331
+Y+I +F KT TP S
Sbjct: 438 QYKIDYLHFHKTYEVPSTPRCS 459
>gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo
sapiens]
Length = 432
Score = 178 bits (451), Expect = 8e-45
Identities = 111/322 (34%), Positives = 173/322 (53%), Gaps = 14/322 (4%)
Query: 17 YRRMVTKDGHSTLQMDGA-QRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLW 75
+ R V K+G ++ ++ YL D + +D+RWR+M+L+FS +F+ WL+F V++
Sbjct: 43 HNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIF 102
Query: 76 YVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAI 135
+V+A +GDLE A T CV + F AAF FS++TQ TI YG + +CP A+
Sbjct: 103 WVIAVAHGDLE---PAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAV 159
Query: 136 ALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTR 195
++ Q ++G ++ +F+ GA +AK+ RPK RA ++ F+ AVVA DGK +++V N R
Sbjct: 160 FMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLR 219
Query: 196 PSPLTSVRVSAVLYQER-----ENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHSITPS 250
S + V A L + R E L Q +D D + F + P+T H I +
Sbjct: 220 KSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFD--KGLDHSFLVSPITILHEIDEA 277
Query: 251 SPLATLLQHE-NPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKG 309
SPL + + + FE+V+ L + E T Q R+SYL +EI+ H F +L K
Sbjct: 278 SPLFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVLF--EKN 335
Query: 310 EYQIKMENFDKTVPEFPTPLVS 331
+Y+I +F KT TP S
Sbjct: 336 QYKIDYLHFHKTYEVPSTPRCS 357
>gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 176 bits (445), Expect = 4e-44
Identities = 114/337 (33%), Positives = 173/337 (51%), Gaps = 23/337 (6%)
Query: 15 QRYRRMVTKDGHSTLQMDG-AQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAV 73
+R R V K+G + + + Y+ D + +D RWR+M+++FSA+F+V WL F +
Sbjct: 16 KRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGL 75
Query: 74 LWYVLAEMNGDLELDHDAP-------------PENHTICVKYITSFTAAFSFSLETQLTI 120
L++ +A +GDLE P P C+ ++ F AF FS+ETQ TI
Sbjct: 76 LFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTTI 135
Query: 121 GYGTMFPSGDCPSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAH 180
GYG + +CP A+ + +Q ++G ++++F+ G +AK+ARPK RA ++ F+ AV++
Sbjct: 136 GYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISV 195
Query: 181 MDGKPNLIFQVANTRPSPLTSVRVSAVLY-----QERENGKLYQTSVDFHLDGISSDECP 235
DGK L+++V N R S + V A L QE E L Q ++ D I D
Sbjct: 196 RDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYD-IGLDRI- 253
Query: 236 FFIFPLTYYHSITPSSPLATLLQHENPSH-FELVVFLSAMQEGTGEICQRRTSYLPSEIM 294
F + P+ H I SPL + + E S FE+VV L M E T Q R+SYL SEI+
Sbjct: 254 FLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEIL 313
Query: 295 LHHCFASLLTRGSKGEYQIKMENFDKTVPEFPTPLVS 331
H F ++ K Y++ F KT TP S
Sbjct: 314 WGHRFEPVVFE-EKSHYKVDYSRFHKTYEVAGTPCCS 349
>gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 176 bits (445), Expect = 4e-44
Identities = 114/337 (33%), Positives = 173/337 (51%), Gaps = 23/337 (6%)
Query: 15 QRYRRMVTKDGHSTLQMDG-AQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAV 73
+R R V K+G + + + Y+ D + +D RWR+M+++FSA+F+V WL F +
Sbjct: 16 KRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLFFGL 75
Query: 74 LWYVLAEMNGDLELDHDAP-------------PENHTICVKYITSFTAAFSFSLETQLTI 120
L++ +A +GDLE P P C+ ++ F AF FS+ETQ TI
Sbjct: 76 LFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQTTI 135
Query: 121 GYGTMFPSGDCPSAIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAH 180
GYG + +CP A+ + +Q ++G ++++F+ G +AK+ARPK RA ++ F+ AV++
Sbjct: 136 GYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAVISV 195
Query: 181 MDGKPNLIFQVANTRPSPLTSVRVSAVLY-----QERENGKLYQTSVDFHLDGISSDECP 235
DGK L+++V N R S + V A L QE E L Q ++ D I D
Sbjct: 196 RDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYD-IGLDRI- 253
Query: 236 FFIFPLTYYHSITPSSPLATLLQHENPSH-FELVVFLSAMQEGTGEICQRRTSYLPSEIM 294
F + P+ H I SPL + + E S FE+VV L M E T Q R+SYL SEI+
Sbjct: 254 FLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEIL 313
Query: 295 LHHCFASLLTRGSKGEYQIKMENFDKTVPEFPTPLVS 331
H F ++ K Y++ F KT TP S
Sbjct: 314 WGHRFEPVVFE-EKSHYKVDYSRFHKTYEVAGTPCCS 349
>gi|62388888 potassium inwardly-rectifying channel J11 [Homo
sapiens]
Length = 390
Score = 161 bits (407), Expect = 1e-39
Identities = 107/323 (33%), Positives = 167/323 (51%), Gaps = 17/323 (5%)
Query: 15 QRYRRMVTKDGHSTLQMDGAQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVL 74
QR R V+K G+ + + +L+D + L+D++W +L+F+ SF+ WL+FA+
Sbjct: 30 QRRARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFAMA 89
Query: 75 WYVLAEMNGDLELDHDAPPENHTI-CVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPS 133
W+++A +GDL AP E CV I SF++AF FS+E Q+TIG+G + +CP
Sbjct: 90 WWLIAFAHGDL-----APSEGTAEPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPL 144
Query: 134 AIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVAN 193
AI +L +Q ++GLM+ A + G K A+ RA ++ F+ AV+A G+ + +V +
Sbjct: 145 AILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGD 204
Query: 194 TRPSPLTSVRVSAVLYQ-----ERENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHSIT 248
R S + S + + + E E L+Q VD ++ F + PL YH I
Sbjct: 205 LRKSMIISATIHMQVVRKTTSPEGEVVPLHQ--VDIPMENGVGGNSIFLVAPLIIYHVID 262
Query: 249 PSSPLATLLQHENPSH--FELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRG 306
+SPL L + H E++V L + E TG Q RTSYL EI+ F ++
Sbjct: 263 ANSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAE- 321
Query: 307 SKGEYQIKMENFDKTVPEFPTPL 329
G Y + F TV + PTPL
Sbjct: 322 EDGRYSVDYSKFGNTV-KVPTPL 343
>gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens]
Length = 424
Score = 160 bits (404), Expect = 2e-39
Identities = 101/316 (31%), Positives = 166/316 (52%), Gaps = 16/316 (5%)
Query: 19 RMVTKDGHSTLQMDGAQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLWYVL 78
R + K G L + +L+D + L+D++WR +++F+ SF+ WL+FA++W+++
Sbjct: 35 RFIAKSGACNLAHKNIREQGRFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLV 94
Query: 79 AEMNGDL-----ELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPS 133
A +GD+ + + T+CV + SFT+AF FS+E Q+TIG+G + +CP
Sbjct: 95 AFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPL 154
Query: 134 AIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVAN 193
AI +L +Q ++GL++ A + G K A+ RA ++ F+ AV+A +GK +F+V +
Sbjct: 155 AITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGD 214
Query: 194 TRPSPL--TSVRVSAVLYQERENGKLYQT-SVDFHLDGISSDECPFFIFPLTYYHSITPS 250
R S + SVR+ V G++ +D +D F + PL H I
Sbjct: 215 LRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHVIDKR 274
Query: 251 SPL----ATLLQHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRG 306
SPL AT L +++ E++V L + E TG Q RTSY+ EI H F S++T
Sbjct: 275 SPLYDISATDLANQD---LEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTE- 330
Query: 307 SKGEYQIKMENFDKTV 322
+G Y + F TV
Sbjct: 331 EEGVYSVDYSKFGNTV 346
>gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens]
Length = 418
Score = 156 bits (395), Expect = 2e-38
Identities = 105/331 (31%), Positives = 175/331 (52%), Gaps = 16/331 (4%)
Query: 18 RRMVTKDGHSTLQMDG--AQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLW 75
RR++ KDG + + G +Y+ D + L+D +WR M ++FS S+++ WL+F ++
Sbjct: 34 RRLLHKDGSCNVYFKHIFGEWG-SYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92
Query: 76 YVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAI 135
+++A +GDL D D P CV + SFT AF FSLETQ TIGYG + +C A+
Sbjct: 93 WLIAFHHGDLLNDPDITP-----CVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAV 147
Query: 136 ALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTR 195
++ +Q +L ++ FI GA +AK+A + RA +IRF+ A++ DGK L++++ + R
Sbjct: 148 LMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFR 207
Query: 196 PSPLT--SVRVSAVLYQERENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHSITPSSPL 253
P+ + +VR + Y E G++ D L ++ + P+T H I SPL
Sbjct: 208 PNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL----VNDQIILVTPVTIVHEIDHESPL 263
Query: 254 ATL-LQHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGEYQ 312
L + +FE++V + TG Q R+SY+P EI+ H F +L K Y+
Sbjct: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRK-YYK 322
Query: 313 IKMENFDKTVPEFPTPLVSKSPNRTDLDIHI 343
+ F+ +V + +K + D +HI
Sbjct: 323 VNCLQFEGSVEVYAPFCSAKQLDWKDQQLHI 353
>gi|25777630 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 156 bits (395), Expect = 2e-38
Identities = 105/331 (31%), Positives = 175/331 (52%), Gaps = 16/331 (4%)
Query: 18 RRMVTKDGHSTLQMDG--AQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLW 75
RR++ KDG + + G +Y+ D + L+D +WR M ++FS S+++ WL+F ++
Sbjct: 34 RRLLHKDGSCNVYFKHIFGEWG-SYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92
Query: 76 YVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAI 135
+++A +GDL D D P CV + SFT AF FSLETQ TIGYG + +C A+
Sbjct: 93 WLIAFHHGDLLNDPDITP-----CVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAV 147
Query: 136 ALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTR 195
++ +Q +L ++ FI GA +AK+A + RA +IRF+ A++ DGK L++++ + R
Sbjct: 148 LMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFR 207
Query: 196 PSPLT--SVRVSAVLYQERENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHSITPSSPL 253
P+ + +VR + Y E G++ D L ++ + P+T H I SPL
Sbjct: 208 PNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL----VNDQIILVTPVTIVHEIDHESPL 263
Query: 254 ATL-LQHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGEYQ 312
L + +FE++V + TG Q R+SY+P EI+ H F +L K Y+
Sbjct: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRK-YYK 322
Query: 313 IKMENFDKTVPEFPTPLVSKSPNRTDLDIHI 343
+ F+ +V + +K + D +HI
Sbjct: 323 VNCLQFEGSVEVYAPFCSAKQLDWKDQQLHI 353
>gi|25777628 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 156 bits (395), Expect = 2e-38
Identities = 105/331 (31%), Positives = 175/331 (52%), Gaps = 16/331 (4%)
Query: 18 RRMVTKDGHSTLQMDG--AQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVLW 75
RR++ KDG + + G +Y+ D + L+D +WR M ++FS S+++ WL+F ++
Sbjct: 34 RRLLHKDGSCNVYFKHIFGEWG-SYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92
Query: 76 YVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSAI 135
+++A +GDL D D P CV + SFT AF FSLETQ TIGYG + +C A+
Sbjct: 93 WLIAFHHGDLLNDPDITP-----CVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAV 147
Query: 136 ALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANTR 195
++ +Q +L ++ FI GA +AK+A + RA +IRF+ A++ DGK L++++ + R
Sbjct: 148 LMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFR 207
Query: 196 PSPLT--SVRVSAVLYQERENGKLYQTSVDFHLDGISSDECPFFIFPLTYYHSITPSSPL 253
P+ + +VR + Y E G++ D L ++ + P+T H I SPL
Sbjct: 208 PNHVVEGTVRAQLLRYTEDSEGRMTMAFKDLKL----VNDQIILVTPVTIVHEIDHESPL 263
Query: 254 ATL-LQHENPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGEYQ 312
L + +FE++V + TG Q R+SY+P EI+ H F +L K Y+
Sbjct: 264 YALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRK-YYK 322
Query: 313 IKMENFDKTVPEFPTPLVSKSPNRTDLDIHI 343
+ F+ +V + +K + D +HI
Sbjct: 323 VNCLQFEGSVEVYAPFCSAKQLDWKDQQLHI 353
>gi|27886667 potassium voltage-gated channel, subfamily H, member 8
[Homo sapiens]
Length = 1107
Score = 34.3 bits (77), Expect = 0.18
Identities = 31/126 (24%), Positives = 59/126 (46%), Gaps = 20/126 (15%)
Query: 57 MLVFSASFVVHWLVFAVLWYVLAEM----NGDLELD----HDAPPE-------NHTICVK 101
+L+ + + HW+ A +WYV+ +M N L+ + H+ N+T+
Sbjct: 358 LLMSMFALLAHWM--ACIWYVIGKMEREDNSLLKWEVGWLHELGKRLESPYYGNNTLGGP 415
Query: 102 YITS-FTAAFSFSLETQLTIGYGTMFPSGDCPSAIALLAIQMLLGLMLEAFITGAFVAKI 160
I S + AA F+L + ++G+G + + D ++ ML+G ++ A + G A I
Sbjct: 416 SIRSAYIAALYFTLSSLTSVGFGNVSANTDAEKIFSICT--MLIGALMHALVFGNVTAII 473
Query: 161 ARPKNR 166
R +R
Sbjct: 474 QRMYSR 479
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.136 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,183,763
Number of Sequences: 37866
Number of extensions: 561081
Number of successful extensions: 1262
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1154
Number of HSP's gapped (non-prelim): 44
length of query: 360
length of database: 18,247,518
effective HSP length: 103
effective length of query: 257
effective length of database: 14,347,320
effective search space: 3687261240
effective search space used: 3687261240
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.