Guide to the Human Genome
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Search of human proteins with 156105695

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156105695 PPAR-alpha interacting complex protein 285 isoform
2 [Homo sapiens]
         (2080 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156105695 PPAR-alpha interacting complex protein 285 isoform ...  4207   0.0  
gi|156105693 PPAR-alpha interacting complex protein 285 isoform ...  4195   0.0  
gi|54792138 helicase with zinc finger domain [Homo sapiens]           272   2e-72
gi|18375673 regulator of nonsense transcripts 1 [Homo sapiens]        184   8e-46
gi|14251207 MOV10-like 1 [Homo sapiens]                               131   8e-30
gi|219521928 DIS3 mitotic control homolog (S. cerevisiae)-like i...   130   2e-29
gi|19115966 DIS3 mitotic control homolog (S. cerevisiae)-like is...   130   2e-29
gi|190014625 DIS3 mitotic control isoform b [Homo sapiens]            119   4e-26
gi|190014623 DIS3 mitotic control isoform a [Homo sapiens]            119   4e-26
gi|194272168 Mov10, Moloney leukemia virus 10, homolog [Homo sap...   117   9e-26
gi|14211540 Mov10, Moloney leukemia virus 10, homolog [Homo sapi...   117   9e-26
gi|119392094 immunoglobulin mu binding protein 2 [Homo sapiens]       115   3e-25
gi|113722133 senataxin [Homo sapiens]                                 109   2e-23
gi|134288890 DIS3 mitotic control homolog (S. cerevisiae)-like 2...   102   4e-21
gi|122937299 DNA replication helicase 2 homolog [Homo sapiens]         90   2e-17
gi|28626521 zinc finger, NFX1-type containing 1 [Homo sapiens]         79   5e-14
gi|38788372 aquarius [Homo sapiens]                                    59   4e-08
gi|239757861 PREDICTED: similar to armadillo repeat containing, ...    37   0.15 
gi|27894378 chloride intracellular channel 6 [Homo sapiens]            37   0.20 
gi|194248057 growth associated protein 43 isoform 1 [Homo sapiens]     36   0.45 
gi|4503911 growth associated protein 43 isoform 2 [Homo sapiens]       36   0.45 
gi|19913396 smoothelin isoform b [Homo sapiens]                        35   0.77 
gi|19913394 smoothelin isoform c [Homo sapiens]                        35   0.77 
gi|19913398 smoothelin isoform a [Homo sapiens]                        35   0.77 
gi|115527120 nebulin [Homo sapiens]                                    34   1.3  
gi|30795231 brain abundant, membrane attached signal protein 1 [...    34   1.7  
gi|24308527 stereocilin [Homo sapiens]                                 34   1.7  
gi|169217788 PREDICTED: similar to putative DUX4 protein [Homo s...    33   2.2  
gi|7657455 pescadillo homolog 1, containing BRCT domain [Homo sa...    33   2.2  
gi|5031579 A-kinase anchor protein 8 [Homo sapiens]                    33   2.2  

>gi|156105695 PPAR-alpha interacting complex protein 285 isoform 2
            [Homo sapiens]
          Length = 2080

 Score = 4207 bits (10911), Expect = 0.0
 Identities = 2080/2080 (100%), Positives = 2080/2080 (100%)

Query: 1    MSSSPSRSAADIYIREYFHSHVSGGHPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQA 60
            MSSSPSRSAADIYIREYFHSHVSGGHPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQA
Sbjct: 1    MSSSPSRSAADIYIREYFHSHVSGGHPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQA 60

Query: 61   FRPPTRAELARHRVVVTTTSQARELRVPVGFFSHILIDEAAQMLECEALTPLAYASHGTR 120
            FRPPTRAELARHRVVVTTTSQARELRVPVGFFSHILIDEAAQMLECEALTPLAYASHGTR
Sbjct: 61   FRPPTRAELARHRVVVTTTSQARELRVPVGFFSHILIDEAAQMLECEALTPLAYASHGTR 120

Query: 121  LVLAGDHMQVTPRLFSVARARAAEHTLLHRLFLCYQQETHEVARQSRLVFHENYRCTDAI 180
            LVLAGDHMQVTPRLFSVARARAAEHTLLHRLFLCYQQETHEVARQSRLVFHENYRCTDAI
Sbjct: 121  LVLAGDHMQVTPRLFSVARARAAEHTLLHRLFLCYQQETHEVARQSRLVFHENYRCTDAI 180

Query: 181  VSFISRHFYVAKGNPIHARGKVPPHPRHYPLMFCHVAGSPDRDMSMASWLNLAEIAQVVE 240
            VSFISRHFYVAKGNPIHARGKVPPHPRHYPLMFCHVAGSPDRDMSMASWLNLAEIAQVVE
Sbjct: 181  VSFISRHFYVAKGNPIHARGKVPPHPRHYPLMFCHVAGSPDRDMSMASWLNLAEIAQVVE 240

Query: 241  KVQEAYNTWPSCWGGREQRCICVVSHGAQVSALRQELRRRDLGQVSVGSFEILPGRQFRV 300
            KVQEAYNTWPSCWGGREQRCICVVSHGAQVSALRQELRRRDLGQVSVGSFEILPGRQFRV
Sbjct: 241  KVQEAYNTWPSCWGGREQRCICVVSHGAQVSALRQELRRRDLGQVSVGSFEILPGRQFRV 300

Query: 301  VVLSTVHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWE 360
            VVLSTVHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWE
Sbjct: 301  VVLSTVHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWE 360

Query: 361  SFIRECVERHSVCPEGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQA 420
            SFIRECVERHSVCPEGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQA
Sbjct: 361  SFIRECVERHSVCPEGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQA 420

Query: 421  AVVTAMVKAEPGDEALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGV 480
            AVVTAMVKAEPGDEALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGV
Sbjct: 421  AVVTAMVKAEPGDEALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGV 480

Query: 481  ESTEAEDAEADFWPWDGELNADDAILRELLDESQKVMVTVGEDGLLDTVARPESLQQARL 540
            ESTEAEDAEADFWPWDGELNADDAILRELLDESQKVMVTVGEDGLLDTVARPESLQQARL
Sbjct: 481  ESTEAEDAEADFWPWDGELNADDAILRELLDESQKVMVTVGEDGLLDTVARPESLQQARL 540

Query: 541  YENLPPAALRKLLHAEPERYRHCSFVPETFERASAIPLDDASSGPIQVRGRLDCGMAFAG 600
            YENLPPAALRKLLHAEPERYRHCSFVPETFERASAIPLDDASSGPIQVRGRLDCGMAFAG
Sbjct: 541  YENLPPAALRKLLHAEPERYRHCSFVPETFERASAIPLDDASSGPIQVRGRLDCGMAFAG 600

Query: 601  DEVLVQLLSGDKAPEGRLRGRVLGVLKRKRHELAFVCRMDTWDPRIMVPINGSVTKIFVA 660
            DEVLVQLLSGDKAPEGRLRGRVLGVLKRKRHELAFVCRMDTWDPRIMVPINGSVTKIFVA
Sbjct: 601  DEVLVQLLSGDKAPEGRLRGRVLGVLKRKRHELAFVCRMDTWDPRIMVPINGSVTKIFVA 660

Query: 661  ELKDPSQVPIYSLRKGRLQRVGLERLTAEARHSRLFWVQIVLWRQGFYYPLGIVREVLPE 720
            ELKDPSQVPIYSLRKGRLQRVGLERLTAEARHSRLFWVQIVLWRQGFYYPLGIVREVLPE
Sbjct: 661  ELKDPSQVPIYSLRKGRLQRVGLERLTAEARHSRLFWVQIVLWRQGFYYPLGIVREVLPE 720

Query: 721  ASTWEQGLRILGLEYSLRVPPSDQATITKVLQKYHTELGRVAGRREDCRAFLTFTVDPQG 780
            ASTWEQGLRILGLEYSLRVPPSDQATITKVLQKYHTELGRVAGRREDCRAFLTFTVDPQG
Sbjct: 721  ASTWEQGLRILGLEYSLRVPPSDQATITKVLQKYHTELGRVAGRREDCRAFLTFTVDPQG 780

Query: 781  ACNLDDALSVRDLGPRCEVAVHITDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPA 840
            ACNLDDALSVRDLGPRCEVAVHITDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPA
Sbjct: 781  ACNLDDALSVRDLGPRCEVAVHITDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPA 840

Query: 841  SLCQDVLSLLPGRDRLAISLFLTMEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHP 900
            SLCQDVLSLLPGRDRLAISLFLTMEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHP
Sbjct: 841  SLCQDVLSLLPGRDRLAISLFLTMEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHP 900

Query: 901  GAGRELPARLDSVDACVVAACYFSRLLRRHRLRSDCFYEQPDEDGTLGFRAAHIMVKEYM 960
            GAGRELPARLDSVDACVVAACYFSRLLRRHRLRSDCFYEQPDEDGTLGFRAAHIMVKEYM
Sbjct: 901  GAGRELPARLDSVDACVVAACYFSRLLRRHRLRSDCFYEQPDEDGTLGFRAAHIMVKEYM 960

Query: 961  IQFNRLVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGG 1020
            IQFNRLVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGG
Sbjct: 961  IQFNRLVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGG 1020

Query: 1021 SPPDTRLHLLASLWKQVQFAARTQDYEQMVDLVTTDDMHPFLAPAGRDLRKALERSAFGR 1080
            SPPDTRLHLLASLWKQVQFAARTQDYEQMVDLVTTDDMHPFLAPAGRDLRKALERSAFGR
Sbjct: 1021 SPPDTRLHLLASLWKQVQFAARTQDYEQMVDLVTTDDMHPFLAPAGRDLRKALERSAFGR 1080

Query: 1081 CARGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARDIDGLCQA 1140
            CARGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARDIDGLCQA
Sbjct: 1081 CARGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARDIDGLCQA 1140

Query: 1141 FSLQHALAQSYQRRARSLHLAVQLKAQPLDKLGFVVDVEAGSRCFRLLFPSNRETLPDPC 1200
            FSLQHALAQSYQRRARSLHLAVQLKAQPLDKLGFVVDVEAGSRCFRLLFPSNRETLPDPC
Sbjct: 1141 FSLQHALAQSYQRRARSLHLAVQLKAQPLDKLGFVVDVEAGSRCFRLLFPSNRETLPDPC 1200

Query: 1201 PVPYGSLQLAEHPHALAGRPGLRLLWRRRVYSAQGSSPPLPLPGTVPDPHTLAVETALWK 1260
            PVPYGSLQLAEHPHALAGRPGLRLLWRRRVYSAQGSSPPLPLPGTVPDPHTLAVETALWK
Sbjct: 1201 PVPYGSLQLAEHPHALAGRPGLRLLWRRRVYSAQGSSPPLPLPGTVPDPHTLAVETALWK 1260

Query: 1261 QLLELVELQRWPEAAALIQEKGEASQRRELVQVQRSHCGHFLEVARELGSGDTLQVQLGT 1320
            QLLELVELQRWPEAAALIQEKGEASQRRELVQVQRSHCGHFLEVARELGSGDTLQVQLGT
Sbjct: 1261 QLLELVELQRWPEAAALIQEKGEASQRRELVQVQRSHCGHFLEVARELGSGDTLQVQLGT 1320

Query: 1321 SLQHGFLVPSPQLWTVAPGFSLCLEHVERPGDCFSGRVYRAPRDRYRDVDEYACVWEPFC 1380
            SLQHGFLVPSPQLWTVAPGFSLCLEHVERPGDCFSGRVYRAPRDRYRDVDEYACVWEPFC
Sbjct: 1321 SLQHGFLVPSPQLWTVAPGFSLCLEHVERPGDCFSGRVYRAPRDRYRDVDEYACVWEPFC 1380

Query: 1381 ALESATGAVAENDSVTLQHLSVSWEASRTPQGQLQGAFRLEAAFLEENCADINFSCCYLC 1440
            ALESATGAVAENDSVTLQHLSVSWEASRTPQGQLQGAFRLEAAFLEENCADINFSCCYLC
Sbjct: 1381 ALESATGAVAENDSVTLQHLSVSWEASRTPQGQLQGAFRLEAAFLEENCADINFSCCYLC 1440

Query: 1441 IRLEGLPAPTASPRPGPSSLGPGLNVDPGTYTWVAHGQTQDWDQERRADRQEAPRRVHLF 1500
            IRLEGLPAPTASPRPGPSSLGPGLNVDPGTYTWVAHGQTQDWDQERRADRQEAPRRVHLF
Sbjct: 1441 IRLEGLPAPTASPRPGPSSLGPGLNVDPGTYTWVAHGQTQDWDQERRADRQEAPRRVHLF 1500

Query: 1501 VHHMGMEKVPEEVLRPGTLFTVELLPKQLPDLRKEEAVRGLEEASPLVTSIALGRPVPQP 1560
            VHHMGMEKVPEEVLRPGTLFTVELLPKQLPDLRKEEAVRGLEEASPLVTSIALGRPVPQP
Sbjct: 1501 VHHMGMEKVPEEVLRPGTLFTVELLPKQLPDLRKEEAVRGLEEASPLVTSIALGRPVPQP 1560

Query: 1561 LCRVIPSRFLERQTYNIPGGRHKLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVF 1620
            LCRVIPSRFLERQTYNIPGGRHKLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVF
Sbjct: 1561 LCRVIPSRFLERQTYNIPGGRHKLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVF 1620

Query: 1621 WFHKSNQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQA 1680
            WFHKSNQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQA
Sbjct: 1621 WFHKSNQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQA 1680

Query: 1681 EASEFPVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGE 1740
            EASEFPVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGE
Sbjct: 1681 EASEFPVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGE 1740

Query: 1741 LFSREDLVWYKKVLWEARKFELDRHEVILCTCSCAASASLKILDVRQILVDEAGMATEPE 1800
            LFSREDLVWYKKVLWEARKFELDRHEVILCTCSCAASASLKILDVRQILVDEAGMATEPE
Sbjct: 1741 LFSREDLVWYKKVLWEARKFELDRHEVILCTCSCAASASLKILDVRQILVDEAGMATEPE 1800

Query: 1801 TLIPLVQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHEDAHMLDTQYRMHE 1860
            TLIPLVQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHEDAHMLDTQYRMHE
Sbjct: 1801 TLIPLVQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHEDAHMLDTQYRMHE 1860

Query: 1861 GICAFPSVAFYKSKLKTWQGLRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNEN 1920
            GICAFPSVAFYKSKLKTWQGLRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNEN
Sbjct: 1861 GICAFPSVAFYKSKLKTWQGLRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNEN 1920

Query: 1921 SKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKALRREGIAGVAVSSIT 1980
            SKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKALRREGIAGVAVSSIT
Sbjct: 1921 SKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKALRREGIAGVAVSSIT 1980

Query: 1981 KSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIG 2040
            KSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIG
Sbjct: 1981 KSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIG 2040

Query: 2041 DHLLLRCCPLWRSLLDFCEAQQTLVPAGQVRVCRRPTMPS 2080
            DHLLLRCCPLWRSLLDFCEAQQTLVPAGQVRVCRRPTMPS
Sbjct: 2041 DHLLLRCCPLWRSLLDFCEAQQTLVPAGQVRVCRRPTMPS 2080


>gi|156105693 PPAR-alpha interacting complex protein 285 isoform 1
            [Homo sapiens]
          Length = 2649

 Score = 4195 bits (10879), Expect = 0.0
 Identities = 2073/2075 (99%), Positives = 2074/2075 (99%)

Query: 6    SRSAADIYIREYFHSHVSGGHPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPT 65
            + SAADIYIREYFHSHVSGGHPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPT
Sbjct: 575  TNSAADIYIREYFHSHVSGGHPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPT 634

Query: 66   RAELARHRVVVTTTSQARELRVPVGFFSHILIDEAAQMLECEALTPLAYASHGTRLVLAG 125
            RAELARHRVVVTTTSQARELRVPVGFFSHILIDEAAQMLECEALTPLAYASHGTRLVLAG
Sbjct: 635  RAELARHRVVVTTTSQARELRVPVGFFSHILIDEAAQMLECEALTPLAYASHGTRLVLAG 694

Query: 126  DHMQVTPRLFSVARARAAEHTLLHRLFLCYQQETHEVARQSRLVFHENYRCTDAIVSFIS 185
            DHMQVTPRLFSVARARAAEHTLLHRLFLCYQQETHEVARQSRLVFHENYRCTDAIVSFIS
Sbjct: 695  DHMQVTPRLFSVARARAAEHTLLHRLFLCYQQETHEVARQSRLVFHENYRCTDAIVSFIS 754

Query: 186  RHFYVAKGNPIHARGKVPPHPRHYPLMFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEA 245
            RHFYVAKGNPIHARGKVPPHPRHYPLMFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEA
Sbjct: 755  RHFYVAKGNPIHARGKVPPHPRHYPLMFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEA 814

Query: 246  YNTWPSCWGGREQRCICVVSHGAQVSALRQELRRRDLGQVSVGSFEILPGRQFRVVVLST 305
            YNTWPSCWGGREQRCICVVSHGAQVSALRQELRRRDLGQVSVGSFEILPGRQFRVVVLST
Sbjct: 815  YNTWPSCWGGREQRCICVVSHGAQVSALRQELRRRDLGQVSVGSFEILPGRQFRVVVLST 874

Query: 306  VHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRE 365
            VHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRE
Sbjct: 875  VHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRE 934

Query: 366  CVERHSVCPEGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTA 425
            CVERHSVCPEGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTA
Sbjct: 935  CVERHSVCPEGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTA 994

Query: 426  MVKAEPGDEALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGVESTEA 485
            MVKAEPGDEALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGVESTEA
Sbjct: 995  MVKAEPGDEALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGVESTEA 1054

Query: 486  EDAEADFWPWDGELNADDAILRELLDESQKVMVTVGEDGLLDTVARPESLQQARLYENLP 545
            EDAEADFWPWDGELNADDAILRELLDESQKVMVTVGEDGLLDTVARPESLQQARLYENLP
Sbjct: 1055 EDAEADFWPWDGELNADDAILRELLDESQKVMVTVGEDGLLDTVARPESLQQARLYENLP 1114

Query: 546  PAALRKLLHAEPERYRHCSFVPETFERASAIPLDDASSGPIQVRGRLDCGMAFAGDEVLV 605
            PAALRKLLHAEPERYRHCSFVPETFERASAIPLDDASSGPIQVRGRLDCGMAFAGDEVLV
Sbjct: 1115 PAALRKLLHAEPERYRHCSFVPETFERASAIPLDDASSGPIQVRGRLDCGMAFAGDEVLV 1174

Query: 606  QLLSGDKAPEGRLRGRVLGVLKRKRHELAFVCRMDTWDPRIMVPINGSVTKIFVAELKDP 665
            QLLSGDKAPEGRLRGRVLGVLKRKRHELAFVCRMDTWDPRIMVPINGSVTKIFVAELKDP
Sbjct: 1175 QLLSGDKAPEGRLRGRVLGVLKRKRHELAFVCRMDTWDPRIMVPINGSVTKIFVAELKDP 1234

Query: 666  SQVPIYSLRKGRLQRVGLERLTAEARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWE 725
            SQVPIYSLRKGRLQRVGLERLTAEARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWE
Sbjct: 1235 SQVPIYSLRKGRLQRVGLERLTAEARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWE 1294

Query: 726  QGLRILGLEYSLRVPPSDQATITKVLQKYHTELGRVAGRREDCRAFLTFTVDPQGACNLD 785
            QGLRILGLEYSLRVPPSDQATITKVLQKYHTELGRVAGRREDCRAFLTFTVDPQGACNLD
Sbjct: 1295 QGLRILGLEYSLRVPPSDQATITKVLQKYHTELGRVAGRREDCRAFLTFTVDPQGACNLD 1354

Query: 786  DALSVRDLGPRCEVAVHITDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQD 845
            DALSVRDLGPRCEVAVHITDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQD
Sbjct: 1355 DALSVRDLGPRCEVAVHITDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQD 1414

Query: 846  VLSLLPGRDRLAISLFLTMEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRE 905
            VLSLLPGRDRLAISLFLTMEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRE
Sbjct: 1415 VLSLLPGRDRLAISLFLTMEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRE 1474

Query: 906  LPARLDSVDACVVAACYFSRLLRRHRLRSDCFYEQPDEDGTLGFRAAHIMVKEYMIQFNR 965
            LPARLDSVDACVVAACYFSRLLRRHRLRSDCFYEQPDEDGTLGFRAAHIMVKEYMIQFNR
Sbjct: 1475 LPARLDSVDACVVAACYFSRLLRRHRLRSDCFYEQPDEDGTLGFRAAHIMVKEYMIQFNR 1534

Query: 966  LVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDT 1025
            LVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDT
Sbjct: 1535 LVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDT 1594

Query: 1026 RLHLLASLWKQVQFAARTQDYEQMVDLVTTDDMHPFLAPAGRDLRKALERSAFGRCARGH 1085
            RLHLLASLWKQVQFAARTQDYEQMVDLVTTDDMHPFLAPAGRDLRKALERSAFGRCARGH
Sbjct: 1595 RLHLLASLWKQVQFAARTQDYEQMVDLVTTDDMHPFLAPAGRDLRKALERSAFGRCARGH 1654

Query: 1086 QQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARDIDGLCQAFSLQH 1145
            QQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARDIDGLCQAFSLQH
Sbjct: 1655 QQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARDIDGLCQAFSLQH 1714

Query: 1146 ALAQSYQRRARSLHLAVQLKAQPLDKLGFVVDVEAGSRCFRLLFPSNRETLPDPCPVPYG 1205
            ALAQSYQRRARSLHLAVQLKAQPLDKLGFVVDVEAGSRCFRLLFPSNRETLPDPCPVPYG
Sbjct: 1715 ALAQSYQRRARSLHLAVQLKAQPLDKLGFVVDVEAGSRCFRLLFPSNRETLPDPCPVPYG 1774

Query: 1206 SLQLAEHPHALAGRPGLRLLWRRRVYSAQGSSPPLPLPGTVPDPHTLAVETALWKQLLEL 1265
            SLQLAEHPHALAGRPGLRLLWRRRVYSAQGSSPPLPLPGTVPDPHTLAVETALWKQLLEL
Sbjct: 1775 SLQLAEHPHALAGRPGLRLLWRRRVYSAQGSSPPLPLPGTVPDPHTLAVETALWKQLLEL 1834

Query: 1266 VELQRWPEAAALIQEKGEASQRRELVQVQRSHCGHFLEVARELGSGDTLQVQLGTSLQHG 1325
            VELQRWPEAAALIQEKGEASQRRELVQVQRSHCGHFLEVARELGSGDTLQVQLGTSLQHG
Sbjct: 1835 VELQRWPEAAALIQEKGEASQRRELVQVQRSHCGHFLEVARELGSGDTLQVQLGTSLQHG 1894

Query: 1326 FLVPSPQLWTVAPGFSLCLEHVERPGDCFSGRVYRAPRDRYRDVDEYACVWEPFCALESA 1385
            FLVPSPQLWTVAPGFSLCLEHVERPGDCFSGRVYRAPRDRYRDVDEYACVWEPFCALESA
Sbjct: 1895 FLVPSPQLWTVAPGFSLCLEHVERPGDCFSGRVYRAPRDRYRDVDEYACVWEPFCALESA 1954

Query: 1386 TGAVAENDSVTLQHLSVSWEASRTPQGQLQGAFRLEAAFLEENCADINFSCCYLCIRLEG 1445
            TGAVAENDSVTLQHLSVSWEASRTPQGQLQGAFRLEAAFLEENCADINFSCCYLCIRLEG
Sbjct: 1955 TGAVAENDSVTLQHLSVSWEASRTPQGQLQGAFRLEAAFLEENCADINFSCCYLCIRLEG 2014

Query: 1446 LPAPTASPRPGPSSLGPGLNVDPGTYTWVAHGQTQDWDQERRADRQEAPRRVHLFVHHMG 1505
            LPAPTASPRPGPSSLGPGLNVDPGTYTWVAHGQTQDWDQERRADRQEAPRRVHLFVHHMG
Sbjct: 2015 LPAPTASPRPGPSSLGPGLNVDPGTYTWVAHGQTQDWDQERRADRQEAPRRVHLFVHHMG 2074

Query: 1506 MEKVPEEVLRPGTLFTVELLPKQLPDLRKEEAVRGLEEASPLVTSIALGRPVPQPLCRVI 1565
            MEKVPEEVLRPGTLFTVELLPKQLPDLRKEEAVRGLEEASPLVTSIALGRPVPQPLCRVI
Sbjct: 2075 MEKVPEEVLRPGTLFTVELLPKQLPDLRKEEAVRGLEEASPLVTSIALGRPVPQPLCRVI 2134

Query: 1566 PSRFLERQTYNIPGGRHKLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKS 1625
            PSRFLERQTYNIPGGRHKLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKS
Sbjct: 2135 PSRFLERQTYNIPGGRHKLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKS 2194

Query: 1626 NQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEF 1685
            NQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEF
Sbjct: 2195 NQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEF 2254

Query: 1686 PVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSRE 1745
            PVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSRE
Sbjct: 2255 PVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSRE 2314

Query: 1746 DLVWYKKVLWEARKFELDRHEVILCTCSCAASASLKILDVRQILVDEAGMATEPETLIPL 1805
            DLVWYKKVLWEARKFELDRHEVILCTCSCAASASLKILDVRQILVDEAGMATEPETLIPL
Sbjct: 2315 DLVWYKKVLWEARKFELDRHEVILCTCSCAASASLKILDVRQILVDEAGMATEPETLIPL 2374

Query: 1806 VQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHEDAHMLDTQYRMHEGICAF 1865
            VQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHEDAHMLDTQYRMHEGICAF
Sbjct: 2375 VQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHEDAHMLDTQYRMHEGICAF 2434

Query: 1866 PSVAFYKSKLKTWQGLRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANL 1925
            PSVAFYKSKLKTWQGLRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANL
Sbjct: 2435 PSVAFYKSKLKTWQGLRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANL 2494

Query: 1926 EEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKALRREGIAGVAVSSITKSQGS 1985
            EEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKALRREGIAGVAVSSITKSQGS
Sbjct: 2495 EEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKALRREGIAGVAVSSITKSQGS 2554

Query: 1986 EWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLL 2045
            EWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLL
Sbjct: 2555 EWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLL 2614

Query: 2046 RCCPLWRSLLDFCEAQQTLVPAGQVRVCRRPTMPS 2080
            RCCPLWRSLLDFCEAQQTLVPAGQVRVCRRPTMPS
Sbjct: 2615 RCCPLWRSLLDFCEAQQTLVPAGQVRVCRRPTMPS 2649


>gi|54792138 helicase with zinc finger domain [Homo sapiens]
          Length = 1942

 Score =  272 bits (696), Expect = 2e-72
 Identities = 160/398 (40%), Positives = 233/398 (58%), Gaps = 30/398 (7%)

Query: 6    SRSAADIYIREYFHSHVSGGHPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPT 65
            S SAAD+YI++Y H +V  G+P+A PLRV + +R +    PV  QYC ++     F+ P 
Sbjct: 699  SNSAADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQ 758

Query: 66   RAELARHRVVVTTTSQAR---ELRVPVGFFSHILIDEAAQMLECEALTPLAYASHGTRLV 122
            + ++ +HRVVV T + ++   +L +  GFF+HIL+DEAAQ +ECE + PLA A+  TR+V
Sbjct: 759  KEDILKHRVVVVTLNTSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALATQNTRIV 818

Query: 123  LAGDHMQVTPRLFS-VARARAAEHTLLHRLFLCYQQETHEVARQSRLVFHENYRCTDAIV 181
            LAGDHMQ++P ++S  AR R    +LL RL+  Y  E        R++  ENYR  +AI+
Sbjct: 819  LAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEF-----PCRILLCENYRSHEAII 873

Query: 182  SFISRHFYVAKGNPIHARGKVPPHPRHYPLMFCHVAGSPDRDMSMASWLNLAEIAQVVEK 241
            ++ S  FY  K   + A GK P H   YPL F    G   ++ +  ++ N AE+ +VVE+
Sbjct: 874  NYTSELFYEGK---LMASGKQPAHKDFYPLTFFTARGEDVQEKNSTAFYNNAEVFEVVER 930

Query: 242  VQEAYNTWPSCWGGREQRCICVVS-HGAQVSALRQELRRRDLGQVSVGSFEILPGRQFRV 300
            V+E    WP  WG  +   I VV+ +  QV  +R ELR++ L  V+V     + G+QFRV
Sbjct: 931  VEELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVNVERVLNVQGKQFRV 990

Query: 301  VVLSTV---HTCQSLLSP------------GALAPEFFTDARVLNTVLTRAQSQLVVVGD 345
            + LSTV   HTC+   +P              L   F ++ ++LNT +TRAQS + VVGD
Sbjct: 991  LFLSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSNYKLLNTAITRAQSLVAVVGD 1050

Query: 346  AVALCSFGACGKLWESFIRECVERHSVCPEGLSMEQVE 383
             +ALCS G C K WE FI  C E  S+   G++ EQ++
Sbjct: 1051 PIALCSIGRCRKFWERFIALCHENSSL--HGITFEQIK 1086



 Score =  113 bits (282), Expect = 2e-24
 Identities = 100/336 (29%), Positives = 149/336 (44%), Gaps = 45/336 (13%)

Query: 1758 RKFELDRHEVILCTCSCAASASLKILDVR-----QILVDEAGMATEPETLIPLVQFPQAE 1812
            +K ++ +H V++ T +   S  L  LD+       IL+DEA  A E ET++PL    Q  
Sbjct: 758  QKEDILKHRVVVVTLN--TSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLALATQNT 815

Query: 1813 KVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHED-------AHMLDTQYRMHEGICAF 1865
            ++VL GDH QL P V +E  +   L  SL +R +E          +L   YR HE I  +
Sbjct: 816  RIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEHYPAEFPCRILLCENYRSHEAIINY 875

Query: 1866 PSVAFYKSKLKTWQGLRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANL 1925
             S  FY+ KL          S    A K+  P+ F   +G +        E N  +  N 
Sbjct: 876  TSELFYEGKLMA--------SGKQPAHKDFYPLTFFTARGED------VQEKNSTAFYNN 921

Query: 1926 EEVAEVVRITKQL-----TLGRTVEPQDIAVLTPYNAQASEISKALRREGIAGVAVSSIT 1980
             EV EVV   ++L          ++   I V+TPY  Q   I   LR++ ++ V V  + 
Sbjct: 922  AEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVFRIRAELRKKRLSDVNVERVL 981

Query: 1981 KSQGSEWRYVLVSTVRTCAKSDLDQRPTK--------SWLKKFLGFVVDPNQVNVAVTRA 2032
              QG ++R + +STVRT       Q P K        S      GF+ +   +N A+TRA
Sbjct: 982  NVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYGFLSNYKLLNTAITRA 1041

Query: 2033 QEGLCLIGDHLLL----RCCPLWRSLLDFCEAQQTL 2064
            Q  + ++GD + L    RC   W   +  C    +L
Sbjct: 1042 QSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSL 1077


>gi|18375673 regulator of nonsense transcripts 1 [Homo sapiens]
          Length = 1118

 Score =  184 bits (467), Expect = 8e-46
 Identities = 157/514 (30%), Positives = 239/514 (46%), Gaps = 86/514 (16%)

Query: 1565 IPSRFLERQTYNIPGGRHKLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHK 1624
            +P RF  +       G   LN SQ  AV+  L++P ++IQGPPGTGKT+    IV+   +
Sbjct: 459  LPKRFTAQ-------GLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLAR 511

Query: 1625 SNQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASE 1684
                  Q  GP           +L C PSN +VD L   +  +  LK +R+ ++  EA +
Sbjct: 512  ------QGNGP-----------VLVCAPSNIAVDQLTEKI-HQTGLKVVRLCAKSREAID 553

Query: 1685 FPVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSR 1744
             PV                        + LH++IR   +    + K    + + GEL S 
Sbjct: 554  SPVS----------------------FLALHNQIRNMDSMPELQ-KLQQLKDETGELSSA 590

Query: 1745 EDLVWYKKVLWEARKFELDRHEVILCTCSCAASASLKILDVRQILVDEAGMATEPETLIP 1804
            ++   Y+ +   A +  L   +VI CTC  A    L  +  R IL+DE+  ATEPE ++P
Sbjct: 591  DEKR-YRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVP 649

Query: 1805 LVQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHE---DAHMLDTQYRMHEG 1861
            +V    A++++L+GDH QL PVV  ++    GL +SLFER          L  QYRMH  
Sbjct: 650  VVL--GAKQLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPA 707

Query: 1862 ICAFPSVAFYKSKLKTWQGLRRPPSVLGHAG----KESCPVIFGHVQGHERSLLVSTDEG 1917
            + AFPS  FY+  L+   G+     V         +   P+ F   QG E      T   
Sbjct: 708  LSAFPSNIFYEGSLQN--GVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTSYL 765

Query: 1918 NENSKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQAS------EISKALRREGI 1971
            N    AN+E++      TK L  G   +P  I ++TPY  Q S      + S +L  +  
Sbjct: 766  NRTEAANVEKIT-----TKLLKAG--AKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLY 818

Query: 1972 AGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTR 2031
              V ++S+   QG E  ++++S VR      +             GF+ DP ++NVA+TR
Sbjct: 819  QEVEIASVDAFQGREKDFIILSCVRANEHQGI-------------GFLNDPRRLNVALTR 865

Query: 2032 AQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLV 2065
            A+ G+ ++G+   L   PLW  LL++ + Q+ LV
Sbjct: 866  ARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLV 899



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 80/303 (26%), Positives = 120/303 (39%), Gaps = 38/303 (12%)

Query: 62  RPPTRAELARHRVVVTTTSQARELRVPVGFFSHILIDEAAQMLECEALTPLAYASHGTRL 121
           R   R  L    V+  T   A + R+    F  ILIDE+ Q  E E + P+   +   +L
Sbjct: 600 RTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPECMVPVVLGAK--QL 657

Query: 122 VLAGDHMQVTPRLFSVARARAA-EHTLLHRLFLCYQQETHEVARQSRLVFHENYRCTDAI 180
           +L GDH Q+ P +     A+A    +L  RL +          R  RL     YR   A+
Sbjct: 658 ILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVLG-------IRPIRL--QVQYRMHPAL 708

Query: 181 VSFISRHFYVAK-GNPIHARGKVP-------PHPRHYPLMFCHVAGSPDRDMSMASWLNL 232
            +F S  FY     N + A  +V        P P   P+ F    G  +   S  S+LN 
Sbjct: 709 SAFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPDK-PMFFYVTQGQEEIASSGTSYLNR 767

Query: 233 AEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGAQVSALRQ------ELRRRDLGQVS 286
            E A V +   +         G +  +   +  +  Q S L Q       L  +   +V 
Sbjct: 768 TEAANVEKITTKLLKA-----GAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVE 822

Query: 287 VGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQLVVVGDA 346
           + S +   GR+   ++LS V   +           F  D R LN  LTRA+  +++VG+ 
Sbjct: 823 IASVDAFQGREKDFIILSCVRANEHQ------GIGFLNDPRRLNVALTRARYGVIIVGNP 876

Query: 347 VAL 349
            AL
Sbjct: 877 KAL 879


>gi|14251207 MOV10-like 1 [Homo sapiens]
          Length = 1211

 Score =  131 bits (329), Expect = 8e-30
 Identities = 145/507 (28%), Positives = 215/507 (42%), Gaps = 120/507 (23%)

Query: 1584 LNPSQNVAVREALE---KPFT-VIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGE 1639
            LN +Q +AV+  L    +P   ++ GPPGTGKT+  +  V   H +              
Sbjct: 745  LNENQKLAVKRILSGDCRPLPYILFGPPGTGKTVTIIEAVLQVHFA-------------- 790

Query: 1640 KRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKS 1699
              L    IL C PSN + D++    LR  E K L+           P   V         
Sbjct: 791  --LPDSRILVCAPSNSAADLVC---LRLHESKVLQ-----------PATMV--------- 825

Query: 1700 PREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEARK 1759
                R N + R       +  A  PY  +                ED+       W+A +
Sbjct: 826  ----RVNATCR---FEEIVIDAVKPYCRD---------------GEDI-------WKASR 856

Query: 1760 FELDRHEVILCTCSCAA---SASLKILDVRQILVDEAGMATEPETLIPL-VQFPQAEKVV 1815
            F      +I+ TCS +       +++     + VDEAG A+EPE LIPL +    + ++V
Sbjct: 857  FR-----IIITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPLGLMSDISGQIV 911

Query: 1816 LLGDHKQLRPVVKNERLQNLGLDRSLFER------YHED--------AH------MLDTQ 1855
            L GD  QL PV+K+      GL+ S  ER      Y  D        AH       L   
Sbjct: 912  LAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAHNPLLVTKLVKN 971

Query: 1856 YRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLG--HAGKESCPVIFGHVQGHERSLLVS 1913
            YR HE +   PS  FY  +L+         S+LG     K+  P+IF  V+G E      
Sbjct: 972  YRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPKKGFPLIFHGVRGSEAR---- 1027

Query: 1914 TDEGNENSKANLEEVAEVVRITKQL--TLGRTVEPQDIAVLTPYNAQASEISKALRREGI 1971
              EG   S  N  E  +V+R    L  ++   V   DI V+TPY  Q  +I   LR   +
Sbjct: 1028 --EGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQVEKIRILLRNVDL 1085

Query: 1972 AGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTR 2031
              + V S+ + QG E+  +++STVR+      D R        FLGF+ +  + NVA+TR
Sbjct: 1086 MDIKVGSVEEFQGQEYLVIIISTVRSNEDRFEDDR-------YFLGFLSNSKRFNVAITR 1138

Query: 2032 AQEGLCLIGD-HLLLRCCPLWRSLLDF 2057
             +  L ++G+ H+L+R  P + +LL++
Sbjct: 1139 PKALLIVLGNPHVLVR-DPCFGALLEY 1164



 Score =  107 bits (267), Expect = 1e-22
 Identities = 118/409 (28%), Positives = 182/409 (44%), Gaps = 42/409 (10%)

Query: 4    SPSRSAADIYIREYFHSHVSGGHPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRP 63
            +PS SAAD+       S V      AT +RV  T R           YC   +D      
Sbjct: 800  APSNSAADLVCLRLHESKVL---QPATMVRVNATCRFEEIVIDAVKPYCRDGEDIW---- 852

Query: 64   PTRAELARHRVVVTTTSQAR---ELRVPVGFFSHILIDEAAQMLECEALTPLAYASH-GT 119
                + +R R+++TT S +    ++ V VG F+H+ +DEA Q  E E L PL   S    
Sbjct: 853  ----KASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPECLIPLGLMSDISG 908

Query: 120  RLVLAGDHMQVTPRLFS-VARARAAEHTLLHRLFL--CYQQE--------THEVARQSRL 168
            ++VLAGD MQ+ P + S +A A     + L RL     YQ++         H     ++L
Sbjct: 909  QIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQRDENAFGACGAHNPLLVTKL 968

Query: 169  VFHENYRCTDAIVSFISRHFYVAK----GNPIHARG-----KVPPHPRHYPLMFCHVAGS 219
            V  +NYR  +A++   SR FY  +     +P          K+P   + +PL+F  V GS
Sbjct: 969  V--KNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKLPK--KGFPLIFHGVRGS 1024

Query: 220  PDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGAQVSALRQELRR 279
              R+    SW N AE  QV+       ++  S     +   I    +  QV  +R  LR 
Sbjct: 1025 EAREGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVI--TPYRKQVEKIRILLRN 1082

Query: 280  RDLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQ 339
             DL  + VGS E   G+++ V+++STV + +           F ++++  N  +TR ++ 
Sbjct: 1083 VDLMDIKVGSVEEFQGQEYLVIIISTVRSNEDRFEDDRYFLGFLSNSKRFNVAITRPKAL 1142

Query: 340  LVVVGDAVALCSFGACGKLWESFIRECVERHSVCPEGL-SMEQVEQGVA 387
            L+V+G+   L      G L E  I   V      P  L S++   +GVA
Sbjct: 1143 LIVLGNPHVLVRDPCFGALLEYSITNGVYMGCDLPPALQSLQNCGEGVA 1191


>gi|219521928 DIS3 mitotic control homolog (S. cerevisiae)-like
            isoform 1 [Homo sapiens]
          Length = 1054

 Score =  130 bits (326), Expect = 2e-29
 Identities = 154/633 (24%), Positives = 264/633 (41%), Gaps = 98/633 (15%)

Query: 586  IQVRGRLDCGMAFAGDEVLVQLLSGDKAPEGRLRGRVLGVLKRKRHELAFVCRMDTWDPR 645
            I + G      +  GD V+V+LL     P+   +GR + + +    + A         P 
Sbjct: 277  ILIHGMKARNRSIHGDVVVVELL-----PKNEWKGRTVALCENDCDDKA-----SGESPS 326

Query: 646  IMVPINGSVTKIFVAELKD-----PSQVPIYSLRKG-----------RLQRVGLERLTAE 689
              +P  G V  I     +D     PS+  + S  K            R+ ++ +    AE
Sbjct: 327  EPMP-TGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAE 385

Query: 690  ARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRVPPSDQATITK 749
                    V+I  W     YP G    VL      E  +  + +E S+ V P  +A + +
Sbjct: 386  TLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCE 445

Query: 750  VLQKYHTELGRVAGRREDCR-----AFLTFTVDPQGACNLDDALSVRDLGP-RCEVAVHI 803
            +         +V+   E  R     + L F++DP+G  ++DD LSVR L     E+ VHI
Sbjct: 446  MPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHI 505

Query: 804  TDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAISLFLT 863
             DV  FV  +  +D+EAR +   +Y   R    MLP+ L  D+ SLL G DR A+S+   
Sbjct: 506  ADVTHFVAPNSYIDIEARTRATTYYLADRR-YDMLPSVLSADLCSLLGGVDRYAVSIMWE 564

Query: 864  MEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRELP--------ARLDSVDA 915
            ++KAS ++K + +  ++++S  +L YE A+E++  +     ++P        +R   ++ 
Sbjct: 565  LDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEE 624

Query: 916  CVVAACYFSRLLRRHRLRSD-C---------FYEQPDEDGTLGFRAAHIMVKEYMIQFNR 965
             V A    + + R  R + D C            Q D+   +     H ++ +  ++ + 
Sbjct: 625  LVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNI-----HDLIPKQPLEVHE 679

Query: 966  LVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDT 1025
             VAE ++       V    W+  P     +AL  +H                    PP  
Sbjct: 680  TVAECMI--LANHWVAKKIWESFPH----QALLRQH-------------------PPPHQ 714

Query: 1026 RLHL-LASLWKQVQFAARTQDYEQMVD-LVTTDDMH-PFLAPAGRDLRKALERSAF---- 1078
                 L    K   F   T+  + + D L   +D H P +    R +      +A     
Sbjct: 715  EFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFST 774

Query: 1079 GRCARGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHG------GSAYSAR 1132
            G CA   +++  HY L +D YT  TSPIRRY D+V+ R ++ A+         G+ +S +
Sbjct: 775  GSCA---EEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNK 831

Query: 1133 DIDGLCQAFSLQHALAQSYQRRARSLHLAVQLK 1165
            D++ LC+  + ++  AQ  Q+++  L   +  K
Sbjct: 832  DLEELCRHINNRNQAAQHSQKQSTELFQCMYFK 864


>gi|19115966 DIS3 mitotic control homolog (S. cerevisiae)-like isoform
            2 [Homo sapiens]
          Length = 971

 Score =  130 bits (326), Expect = 2e-29
 Identities = 154/633 (24%), Positives = 264/633 (41%), Gaps = 98/633 (15%)

Query: 586  IQVRGRLDCGMAFAGDEVLVQLLSGDKAPEGRLRGRVLGVLKRKRHELAFVCRMDTWDPR 645
            I + G      +  GD V+V+LL     P+   +GR + + +    + A         P 
Sbjct: 194  ILIHGMKARNRSIHGDVVVVELL-----PKNEWKGRTVALCENDCDDKA-----SGESPS 243

Query: 646  IMVPINGSVTKIFVAELKD-----PSQVPIYSLRKG-----------RLQRVGLERLTAE 689
              +P  G V  I     +D     PS+  + S  K            R+ ++ +    AE
Sbjct: 244  EPMP-TGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAE 302

Query: 690  ARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRVPPSDQATITK 749
                    V+I  W     YP G    VL      E  +  + +E S+ V P  +A + +
Sbjct: 303  TLQDFRVVVRIDSWESTSVYPNGHFVRVLGRIGDLEGEIATILVENSISVIPFSEAQMCE 362

Query: 750  VLQKYHTELGRVAGRREDCR-----AFLTFTVDPQGACNLDDALSVRDLGP-RCEVAVHI 803
            +         +V+   E  R     + L F++DP+G  ++DD LSVR L     E+ VHI
Sbjct: 363  MPVNTPESPWKVSPEEEQKRKDLRKSHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHI 422

Query: 804  TDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAISLFLT 863
             DV  FV  +  +D+EAR +   +Y   R    MLP+ L  D+ SLL G DR A+S+   
Sbjct: 423  ADVTHFVAPNSYIDIEARTRATTYYLADRR-YDMLPSVLSADLCSLLGGVDRYAVSIMWE 481

Query: 864  MEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRELP--------ARLDSVDA 915
            ++KAS ++K + +  ++++S  +L YE A+E++  +     ++P        +R   ++ 
Sbjct: 482  LDKASYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNLSVVDDIPEFKDLDEKSRQAKLEE 541

Query: 916  CVVAACYFSRLLRRHRLRSD-C---------FYEQPDEDGTLGFRAAHIMVKEYMIQFNR 965
             V A    + + R  R + D C            Q D+   +     H ++ +  ++ + 
Sbjct: 542  LVWAIGKLTDIARHVRAKRDGCGALELEGVEVCVQLDDKKNI-----HDLIPKQPLEVHE 596

Query: 966  LVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDT 1025
             VAE ++       V    W+  P     +AL  +H                    PP  
Sbjct: 597  TVAECMI--LANHWVAKKIWESFPH----QALLRQH-------------------PPPHQ 631

Query: 1026 RLHL-LASLWKQVQFAARTQDYEQMVD-LVTTDDMH-PFLAPAGRDLRKALERSAF---- 1078
                 L    K   F   T+  + + D L   +D H P +    R +      +A     
Sbjct: 632  EFFSELRECAKAKGFFIDTRSNKTLADSLDNANDPHDPIVNRLLRSMATQAMSNALYFST 691

Query: 1079 GRCARGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHG------GSAYSAR 1132
            G CA   +++  HY L +D YT  TSPIRRY D+V+ R ++ A+         G+ +S +
Sbjct: 692  GSCA---EEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKGNLFSNK 748

Query: 1133 DIDGLCQAFSLQHALAQSYQRRARSLHLAVQLK 1165
            D++ LC+  + ++  AQ  Q+++  L   +  K
Sbjct: 749  DLEELCRHINNRNQAAQHSQKQSTELFQCMYFK 781


>gi|190014625 DIS3 mitotic control isoform b [Homo sapiens]
          Length = 928

 Score =  119 bits (297), Expect = 4e-26
 Identities = 136/568 (23%), Positives = 224/568 (39%), Gaps = 87/568 (15%)

Query: 620  GRVLGVLKRKRHELAFVCRMDTWDPRIMVPINGSVTKIFVAELKDPSQVPIYSLRKGRLQ 679
            GRV+G++KR             W P       G ++K  + E    S+  +++    R+ 
Sbjct: 313  GRVVGIIKRN------------WRPYC-----GMLSKSDIKE----SRRHLFTPADKRIP 351

Query: 680  RVGLERLTAEARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRV 739
            R+ +E   A     R   V I  W +   YP G     L +    E    +L LE+ +  
Sbjct: 352  RIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPH 411

Query: 740  PPSDQATITKVLQKYHTELGRVAGRREDCRAFLTFTVDPQGACNLDDALSVRDL-GPRCE 798
             P  QA ++ + +   +   +    RED R     +VDP G  ++DDAL  R+L     E
Sbjct: 412  QPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLE 471

Query: 799  VAVHITDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAI 858
            V VHI DV+ F+     LD E+ R+G   Y   +  + M+P  L  ++ SL    DRLA 
Sbjct: 472  VGVHIADVSHFIRPGNALDQESARRGTTVYLCEKR-IDMVPELLSSNLCSLKCDVDRLAF 530

Query: 859  SLFLTMEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRELPARLDSVDACVV 918
            S    M   +  LK+ +F  SV+ S   L+Y EA+  I        +     D +   + 
Sbjct: 531  SCIWEMNHNAEILKT-KFTKSVINSKASLTYAEAQLRI--------DSANMNDDITTSLR 581

Query: 919  AACYFSRLLRRHRLRS--------------DCFYEQPDEDGTLGFRAAHIMVKEYMIQFN 964
                 +++L++ R+                D     P +  T   R  + MV+E+M+  N
Sbjct: 582  GLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFMLLAN 641

Query: 965  RLVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPD 1024
              VA                          K + E+  +   L  H          +PP 
Sbjct: 642  ISVA--------------------------KKIHEEFSEHALLRKH---------PAPPP 666

Query: 1025 TRLHLLASLWKQVQFAARTQDYEQMVDLV--TTDDMHPFLAPAGRDLRKALERSAFGRCA 1082
            +   +L    +      +T   + + + +        P+L    R L       A   C+
Sbjct: 667  SNYEILVKAARSRNLEIKTDTAKSLAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCS 726

Query: 1083 RGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARD---IDGLCQ 1139
             G      HY L    YT  TSPIRRY DV++ R + +A+G   +     D   +  +C+
Sbjct: 727  -GMDNDFHHYGLASPIYTHFTSPIRRYADVIVHRLLAVAIGADCTYPELTDKHKLADICK 785

Query: 1140 AFSLQHALAQSYQRRARSLHLAVQLKAQ 1167
              + +H +AQ  QR + + H  +  K++
Sbjct: 786  NLNFRHKMAQYAQRASVAFHTQLFFKSK 813


>gi|190014623 DIS3 mitotic control isoform a [Homo sapiens]
          Length = 958

 Score =  119 bits (297), Expect = 4e-26
 Identities = 136/568 (23%), Positives = 224/568 (39%), Gaps = 87/568 (15%)

Query: 620  GRVLGVLKRKRHELAFVCRMDTWDPRIMVPINGSVTKIFVAELKDPSQVPIYSLRKGRLQ 679
            GRV+G++KR             W P       G ++K  + E    S+  +++    R+ 
Sbjct: 343  GRVVGIIKRN------------WRPYC-----GMLSKSDIKE----SRRHLFTPADKRIP 381

Query: 680  RVGLERLTAEARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRV 739
            R+ +E   A     R   V I  W +   YP G     L +    E    +L LE+ +  
Sbjct: 382  RIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPH 441

Query: 740  PPSDQATITKVLQKYHTELGRVAGRREDCRAFLTFTVDPQGACNLDDALSVRDL-GPRCE 798
             P  QA ++ + +   +   +    RED R     +VDP G  ++DDAL  R+L     E
Sbjct: 442  QPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLE 501

Query: 799  VAVHITDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAI 858
            V VHI DV+ F+     LD E+ R+G   Y   +  + M+P  L  ++ SL    DRLA 
Sbjct: 502  VGVHIADVSHFIRPGNALDQESARRGTTVYLCEKR-IDMVPELLSSNLCSLKCDVDRLAF 560

Query: 859  SLFLTMEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRELPARLDSVDACVV 918
            S    M   +  LK+ +F  SV+ S   L+Y EA+  I        +     D +   + 
Sbjct: 561  SCIWEMNHNAEILKT-KFTKSVINSKASLTYAEAQLRI--------DSANMNDDITTSLR 611

Query: 919  AACYFSRLLRRHRLRS--------------DCFYEQPDEDGTLGFRAAHIMVKEYMIQFN 964
                 +++L++ R+                D     P +  T   R  + MV+E+M+  N
Sbjct: 612  GLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETNSMVEEFMLLAN 671

Query: 965  RLVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPD 1024
              VA                          K + E+  +   L  H          +PP 
Sbjct: 672  ISVA--------------------------KKIHEEFSEHALLRKH---------PAPPP 696

Query: 1025 TRLHLLASLWKQVQFAARTQDYEQMVDLV--TTDDMHPFLAPAGRDLRKALERSAFGRCA 1082
            +   +L    +      +T   + + + +        P+L    R L       A   C+
Sbjct: 697  SNYEILVKAARSRNLEIKTDTAKSLAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCS 756

Query: 1083 RGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARD---IDGLCQ 1139
             G      HY L    YT  TSPIRRY DV++ R + +A+G   +     D   +  +C+
Sbjct: 757  -GMDNDFHHYGLASPIYTHFTSPIRRYADVIVHRLLAVAIGADCTYPELTDKHKLADICK 815

Query: 1140 AFSLQHALAQSYQRRARSLHLAVQLKAQ 1167
              + +H +AQ  QR + + H  +  K++
Sbjct: 816  NLNFRHKMAQYAQRASVAFHTQLFFKSK 843


>gi|194272168 Mov10, Moloney leukemia virus 10, homolog [Homo sapiens]
          Length = 1003

 Score =  117 bits (294), Expect = 9e-26
 Identities = 140/524 (26%), Positives = 216/524 (41%), Gaps = 133/524 (25%)

Query: 1585 NPSQNVAVREALE-----KPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGE 1639
            NP Q  A+R  +       P+ +I GPPGTGKT+  +  +        +QV         
Sbjct: 500  NPEQLQAMRHIVTGTTRPAPY-IIFGPPGTGKTVTLVEAI--------KQVV-------- 542

Query: 1640 KRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKS 1699
            K L    IL C PSN   D+L   L  R+ L P  +Y   A + +           +R  
Sbjct: 543  KHLPKAHILACAPSNSGADLLCQRL--RVHL-PSSIYRLLAPSRD-----------IRMV 588

Query: 1700 PREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEARK 1759
            P + +P                           +   ++GE             ++ A+K
Sbjct: 589  PEDIKP-------------------------CCNWDAKKGEY------------VFPAKK 611

Query: 1760 FELDRHEVILCTCSCAA---SASLKILDVRQILVDEAGMATEPETLIPLVQFPQAEK--- 1813
             +L  + V++ T   A    SA   I     I +DEAG   EPE+L+ +    + ++   
Sbjct: 612  -KLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIAGLMEVKETGD 670

Query: 1814 ----VVLLGDHKQLRPVVKNERLQNLGLDRSLFER-------YHEDAHMLDTQ------- 1855
                +VL GD +QL PV+++   Q  GL  SL ER       Y +     D Q       
Sbjct: 671  PGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGYDPQFITKLLR 730

Query: 1856 -YRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAG--KESCPVIFGHVQGHERSLLV 1912
             YR H  I   P+  +Y+ +L+    +         AG  ++  P+IF  V G +     
Sbjct: 731  NYRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFHGVMGKDER--- 787

Query: 1913 STDEGNENSKANLEEVAEVVRITKQLTLGRT------VEPQDIAVLTPYNAQASEISKAL 1966
               EGN  S  N EE A V    K L    +      + P+ + V++PY  Q  +I   +
Sbjct: 788  ---EGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPYRKQVEKIRYCI 844

Query: 1967 RR--------EGIAGVAVSSITKSQGSEWRYVLVSTVRTC---AKSDLDQRPTKSWLKKF 2015
             +        + I  + V S+ + QG E   +L+STVR+     + DLD           
Sbjct: 845  TKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFN--------- 895

Query: 2016 LGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCE 2059
            LGF+ +P + NVAVTRA+  L ++G+ LLL   P W+  L+FC+
Sbjct: 896  LGFLKNPKRFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCK 939



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 106/414 (25%), Positives = 184/414 (44%), Gaps = 56/414 (13%)

Query: 1   MSSSPSRSAADIYIREYFHSHVSGGHPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQA 60
           ++ +PS S AD+  +          H  ++  R++   R +    P  ++ CC  D ++ 
Sbjct: 551 LACAPSNSGADLLCQRL------RVHLPSSIYRLLAPSRDIRMV-PEDIKPCCNWDAKKG 603

Query: 61  -FRPPTRAELARHRVVVTTTSQAREL---RVPVGFFSHILIDEAAQMLECEALTPLA--- 113
            +  P + +L  +RV++TT   A  L   + P+  F+HI IDEA   +E E+L  +A   
Sbjct: 604 EYVFPAKKKLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIAGLM 663

Query: 114 ----YASHGTRLVLAGDHMQVTPRLFS-VARARAAEHTLLHRLFL---CYQQETHEVARQ 165
                   G +LVLAGD  Q+ P L S + +     ++LL RL      Y++       Q
Sbjct: 664 EVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGYDPQ 723

Query: 166 SRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRH----------YPLMFCH 215
                  NYR    I+   ++ +Y  +   + A   V    R           +P++F  
Sbjct: 724 FITKLLRNYRSHPTILDIPNQLYYEGE---LQACADVVDRERFCRWAGLPRQGFPIIFHG 780

Query: 216 VAGSPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQ---RCICVVS-HGAQVS 271
           V G  +R+ +  S+ N  E A V   ++      PS   G+ +   R + V+S +  QV 
Sbjct: 781 VMGKDEREGNSPSFFNPEEAATVTSYLKLLLA--PSSKKGKARLSPRSVGVISPYRKQVE 838

Query: 272 ALR-------QELR-RRDLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGA-LAPEF 322
            +R       +ELR   D+  + VGS E   G++  V+++STV + QS +         F
Sbjct: 839 KIRYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGF 898

Query: 323 FTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVER--HSVCP 374
             + +  N  +TRA++ L++VG+ + L         W+ F+  C E   ++ CP
Sbjct: 899 LKNPKRFNVAVTRAKALLIIVGNPLLL----GHDPDWKVFLEFCKENGGYTGCP 948


>gi|14211540 Mov10, Moloney leukemia virus 10, homolog [Homo sapiens]
          Length = 1003

 Score =  117 bits (294), Expect = 9e-26
 Identities = 140/524 (26%), Positives = 216/524 (41%), Gaps = 133/524 (25%)

Query: 1585 NPSQNVAVREALE-----KPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGE 1639
            NP Q  A+R  +       P+ +I GPPGTGKT+  +  +        +QV         
Sbjct: 500  NPEQLQAMRHIVTGTTRPAPY-IIFGPPGTGKTVTLVEAI--------KQVV-------- 542

Query: 1640 KRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKS 1699
            K L    IL C PSN   D+L   L  R+ L P  +Y   A + +           +R  
Sbjct: 543  KHLPKAHILACAPSNSGADLLCQRL--RVHL-PSSIYRLLAPSRD-----------IRMV 588

Query: 1700 PREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEARK 1759
            P + +P                           +   ++GE             ++ A+K
Sbjct: 589  PEDIKP-------------------------CCNWDAKKGEY------------VFPAKK 611

Query: 1760 FELDRHEVILCTCSCAA---SASLKILDVRQILVDEAGMATEPETLIPLVQFPQAEK--- 1813
             +L  + V++ T   A    SA   I     I +DEAG   EPE+L+ +    + ++   
Sbjct: 612  -KLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIAGLMEVKETGD 670

Query: 1814 ----VVLLGDHKQLRPVVKNERLQNLGLDRSLFER-------YHEDAHMLDTQ------- 1855
                +VL GD +QL PV+++   Q  GL  SL ER       Y +     D Q       
Sbjct: 671  PGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGYDPQFITKLLR 730

Query: 1856 -YRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAG--KESCPVIFGHVQGHERSLLV 1912
             YR H  I   P+  +Y+ +L+    +         AG  ++  P+IF  V G +     
Sbjct: 731  NYRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFHGVMGKDER--- 787

Query: 1913 STDEGNENSKANLEEVAEVVRITKQLTLGRT------VEPQDIAVLTPYNAQASEISKAL 1966
               EGN  S  N EE A V    K L    +      + P+ + V++PY  Q  +I   +
Sbjct: 788  ---EGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPYRKQVEKIRYCI 844

Query: 1967 RR--------EGIAGVAVSSITKSQGSEWRYVLVSTVRTC---AKSDLDQRPTKSWLKKF 2015
             +        + I  + V S+ + QG E   +L+STVR+     + DLD           
Sbjct: 845  TKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFN--------- 895

Query: 2016 LGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCE 2059
            LGF+ +P + NVAVTRA+  L ++G+ LLL   P W+  L+FC+
Sbjct: 896  LGFLKNPKRFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCK 939



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 106/414 (25%), Positives = 184/414 (44%), Gaps = 56/414 (13%)

Query: 1   MSSSPSRSAADIYIREYFHSHVSGGHPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQA 60
           ++ +PS S AD+  +          H  ++  R++   R +    P  ++ CC  D ++ 
Sbjct: 551 LACAPSNSGADLLCQRL------RVHLPSSIYRLLAPSRDIRMV-PEDIKPCCNWDAKKG 603

Query: 61  -FRPPTRAELARHRVVVTTTSQAREL---RVPVGFFSHILIDEAAQMLECEALTPLA--- 113
            +  P + +L  +RV++TT   A  L   + P+  F+HI IDEA   +E E+L  +A   
Sbjct: 604 EYVFPAKKKLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIAGLM 663

Query: 114 ----YASHGTRLVLAGDHMQVTPRLFS-VARARAAEHTLLHRLFL---CYQQETHEVARQ 165
                   G +LVLAGD  Q+ P L S + +     ++LL RL      Y++       Q
Sbjct: 664 EVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGYDPQ 723

Query: 166 SRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRH----------YPLMFCH 215
                  NYR    I+   ++ +Y  +   + A   V    R           +P++F  
Sbjct: 724 FITKLLRNYRSHPTILDIPNQLYYEGE---LQACADVVDRERFCRWAGLPRQGFPIIFHG 780

Query: 216 VAGSPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQ---RCICVVS-HGAQVS 271
           V G  +R+ +  S+ N  E A V   ++      PS   G+ +   R + V+S +  QV 
Sbjct: 781 VMGKDEREGNSPSFFNPEEAATVTSYLKLLLA--PSSKKGKARLSPRSVGVISPYRKQVE 838

Query: 272 ALR-------QELR-RRDLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGA-LAPEF 322
            +R       +ELR   D+  + VGS E   G++  V+++STV + QS +         F
Sbjct: 839 KIRYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGF 898

Query: 323 FTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVER--HSVCP 374
             + +  N  +TRA++ L++VG+ + L         W+ F+  C E   ++ CP
Sbjct: 899 LKNPKRFNVAVTRAKALLIIVGNPLLL----GHDPDWKVFLEFCKENGGYTGCP 948


>gi|119392094 immunoglobulin mu binding protein 2 [Homo sapiens]
          Length = 993

 Score =  115 bits (289), Expect = 3e-25
 Identities = 146/547 (26%), Positives = 218/547 (39%), Gaps = 113/547 (20%)

Query: 1544 ASPLVTSIALGRPVPQPLCRVIPSRFLERQTYNIPGGRHKLNPSQNVAVREAL-EKPFTV 1602
            AS L+  +  GR  P P   + P  F              L+ SQ  AV  AL +K   +
Sbjct: 163  ASSLI-EVLFGRSAPSPASEIHPLTFFNTC----------LDTSQKEAVLFALSQKELAI 211

Query: 1603 IQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAG 1662
            I GPPGTGKT   + I+    K                   G  +L C PSN +VD L  
Sbjct: 212  IHGPPGTGKTTTVVEIILQAVKQ------------------GLKVLCCAPSNIAVDNL-- 251

Query: 1663 LLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAP 1722
              + R+ L   R+                         R G P + L SI  H       
Sbjct: 252  --VERLALCKQRIL------------------------RLGHPARLLESIQQHSLDAVLA 285

Query: 1723 NPYSSEIKAFDTRLQRGELFS--------------REDLVWYKKVLWEARKF----ELDR 1764
               S++I A D R    ++F               R ++   +K L E  +      L  
Sbjct: 286  RSDSAQIVA-DIRKDIDQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTS 344

Query: 1765 HEVILCT-CSCAASASLKILDVRQ---ILVDEAGMATEPETLIPLVQFPQAEKVVLLGDH 1820
              V+L T    +A   LK+L       +++DE   A E    IPL++   A K +L GDH
Sbjct: 345  ANVVLATNTGASADGPLKLLPESYFDVVVIDECAQALEASCWIPLLK---ARKCILAGDH 401

Query: 1821 KQLRPVVKNERLQNLGLDRSLFERYHED-----AHMLDTQYRMHEGICAFPSVAFYKSKL 1875
            KQL P   + +    GL  SL ER  E+        L  QYRMH+ I  + S   Y  +L
Sbjct: 402  KQLPPTTVSHKAALAGLSLSLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQL 461

Query: 1876 KTWQG-----LRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANLEEVAE 1930
                      LR  P V     +   P++     G     L   +E +E SK N  EV  
Sbjct: 462  TAHSSVARHLLRDLPGVAA-TEETGVPLLLVDTAG---CGLFELEEEDEQSKGNPGEV-R 516

Query: 1931 VVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKALRREGIAGVAVSSITKSQGSEWRYV 1990
            +V +  Q  +   V  +DIAV++PYN Q   + ++L       + + S+   QG E   V
Sbjct: 517  LVSLHIQALVDAGVPARDIAVVSPYNLQVDLLRQSLVHRH-PELEIKSVDGFQGREKEAV 575

Query: 1991 LVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPL 2050
            ++S VR+  K +             +GF+ +  ++NVAVTRA+  + +I D   +     
Sbjct: 576  ILSFVRSNRKGE-------------VGFLAEDRRINVAVTRARRHVAVICDSRTVNNHAF 622

Query: 2051 WRSLLDF 2057
             ++L+++
Sbjct: 623  LKTLVEY 629



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 100/416 (24%), Positives = 159/416 (38%), Gaps = 65/416 (15%)

Query: 87  VPVGFFSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFSVARARAA-EH 145
           +P  +F  ++IDE AQ LE     PL  A    + +LAGDH Q+ P   S   A A    
Sbjct: 364 LPESYFDVVVIDECAQALEASCWIPLLKAR---KCILAGDHKQLPPTTVSHKAALAGLSL 420

Query: 146 TLLHRLFLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPH 205
           +L+ RL         E   +        YR   AI+ + S   Y+ +   + A   V  H
Sbjct: 421 SLMERL-------AEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQ---LTAHSSVARH 470

Query: 206 ------------PRHYPLMFCHVAGS---PDRDMSMASWLNLAEIAQVVEKVQEAYNTWP 250
                           PL+    AG       +    S  N  E+  V   +Q   +   
Sbjct: 471 LLRDLPGVAATEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVD--- 527

Query: 251 SCWGGREQRCICVVS-HGAQVSALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTVHTC 309
               G   R I VVS +  QV  LRQ L  R   ++ + S +   GR+   V+LS V + 
Sbjct: 528 ---AGVPARDIAVVSPYNLQVDLLRQSLVHRH-PELEIKSVDGFQGREKEAVILSFVRSN 583

Query: 310 QSLLSPGALAPEFFTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVER 369
           +     G +   F  + R +N  +TRA+  + V+ D+  + +      L E F +    R
Sbjct: 584 RK----GEVG--FLAEDRRINVAVTRARRHVAVICDSRTVNNHAFLKTLVEYFTQHGEVR 637

Query: 370 HSVCPEGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKA 429
                   + E ++  V      P   +   + G+  AA +P G     +    T   + 
Sbjct: 638 -------TAFEYLDDIV------PENYSHENSQGSSHAATKPQGPATSTR----TGSQRQ 680

Query: 430 EPGDEALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGVESTEA 485
           E G EA +PA +       ++ A+ AP+  ++      G    G  +  GV+   A
Sbjct: 681 EGGQEAAAPARQGRKKPAGKSLASEAPSQPSLN-----GGSPEGVESQDGVDHFRA 731


>gi|113722133 senataxin [Homo sapiens]
          Length = 2677

 Score =  109 bits (273), Expect = 2e-23
 Identities = 135/530 (25%), Positives = 229/530 (43%), Gaps = 107/530 (20%)

Query: 1602 VIQGPPGTGK--TIVGLHIVFWFHKSNQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDV 1659
            +I GPPGTGK  TIVGL     +    + Q +         ++    +L C PSN +VD 
Sbjct: 1960 LIHGPPGTGKSKTIVGL----LYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDE 2015

Query: 1660 LAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKSPREGRPNQSLR---SITLHH 1716
            L    ++++ L+    + E+ +  + P+   G   L+R  P +   ++ L+      ++H
Sbjct: 2016 L----MKKIILE----FKEKCKDKKNPLGNCGDINLVRLGPEKSINSEVLKFSLDSQVNH 2067

Query: 1717 RIRQAPNPYSSEIKAFDTR-----------------------LQRGELFS--------RE 1745
            R+++      S ++A   R                       +QR EL          R+
Sbjct: 2068 RMKKE---LPSHVQAMHKRKEFLDYQLDELSRQRALCRGGREIQRQELDENISKVSKERQ 2124

Query: 1746 DLVW-YKKVLWEARKFE----LDRHEVILCTCSCAASASLKILDVRQ-------ILVDEA 1793
            +L    K+V    +K +    L+ H +I CT S +    L+     Q       ++VDEA
Sbjct: 2125 ELASKIKEVQGRPQKTQSIIILESH-IICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEA 2183

Query: 1794 GMATEPETLIPLVQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERY----HEDA 1849
            G + E ETL PL+   +  K++L+GD KQL P V + + Q  G D+S+  R+     E+ 
Sbjct: 2184 GQSCEIETLTPLIH--RCNKLILVGDPKQLPPTVISMKAQEYGYDQSMMARFCRLLEENV 2241

Query: 1850 H----------MLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAGKESCP-V 1898
                        L  QYRMH  IC FPS   Y   LKT    R+  ++   +     P +
Sbjct: 2242 EHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKT---NRQTEAIRCSSDWPFQPYL 2298

Query: 1899 IFGHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGR-TVEPQDIAVLTPYNA 1957
            +F    G ER         + +S  N++E+  V+ I K +   R  V  ++I ++T Y A
Sbjct: 2299 VFDVGDGSERR--------DNDSYINVQEIKLVMEIIKLIKDKRKDVSFRNIGIITHYKA 2350

Query: 1958 QASEISKALRRE--GIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKF 2015
            Q + I K L +E        V ++   QG +   V+V+ VR             + ++  
Sbjct: 2351 QKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRA------------NSIQGS 2398

Query: 2016 LGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLV 2065
            +GF+    ++NV +TRA+  L ++G    L     W  L+   + +  ++
Sbjct: 2399 IGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNQLIQDAQKRGAII 2448



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 71/290 (24%), Positives = 126/290 (43%), Gaps = 26/290 (8%)

Query: 92   FSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFSV-ARARAAEHTLLHR 150
            FS +++DEA Q  E E LTPL +  +  +L+L GD  Q+ P + S+ A+    + +++ R
Sbjct: 2175 FSCVIVDEAGQSCEIETLTPLIHRCN--KLILVGDPKQLPPTVISMKAQEYGYDQSMMAR 2232

Query: 151  LFLCYQQ--ETHEVARQSRLVFHENYRCTDAIVSFISRHFY---VAKGNPIHARGKVPPH 205
                 ++  E + ++R   L     YR    I  F S + Y   +       A       
Sbjct: 2233 FCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTNRQTEAIRCSSDW 2292

Query: 206  PRHYPLMFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVS 265
            P    L+F    GS  RD    S++N+ EI  V+E ++   +           R I +++
Sbjct: 2293 PFQPYLVFDVGDGSERRDND--SYINVQEIKLVMEIIKLIKDKRKDV----SFRNIGIIT 2346

Query: 266  H-GAQVSALRQELRRR--DLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEF 322
            H  AQ + ++++L +     G   V + +   GRQ   V+++ V       S G     F
Sbjct: 2347 HYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIG-----F 2401

Query: 323  FTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVERHSV 372
                + LN  +TRA+  L ++G    L       + W   I++  +R ++
Sbjct: 2402 LASLQRLNVTITRAKYSLFILGHLRTLME----NQHWNQLIQDAQKRGAI 2447


>gi|134288890 DIS3 mitotic control homolog (S. cerevisiae)-like 2
            [Homo sapiens]
          Length = 885

 Score =  102 bits (254), Expect = 4e-21
 Identities = 139/519 (26%), Positives = 215/519 (41%), Gaps = 76/519 (14%)

Query: 695  LFWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRVPPSDQATITKVLQKY 754
            LF  +IV W++   + LG + + L +A   E     +  EY +         +  + Q  
Sbjct: 300  LFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQGL 359

Query: 755  HTELG-RVAGRREDCRAFLTFTVDPQGACNLDDALSVRDLGP-RCEVAVHITDVASFVPR 812
               +      +R D R    FT+DP  A +LDDALS + L     +V VHI DV+ FVP 
Sbjct: 360  PWTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPE 419

Query: 813  DGVLDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAISLFLTMEKASGQLK 872
               LD  A  +  + Y   ++ VPMLP  LC+++ SL P  D+L  S+  T+    G++ 
Sbjct: 420  GSDLDKVAAERATSVYLV-QKVVPMLPRLLCEELCSLNPMSDKLTFSVIWTL-TPEGKIL 477

Query: 873  SLRFAPSVVQSDRQLSYEEAEEVIRQ--HPGAGRELPA-----RLDSVDACVVAACYFSR 925
               F  ++++S  +LSYE A+ +I         +ELP        + V   V+     ++
Sbjct: 478  DEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQAVLNLHGIAK 537

Query: 926  LLRRHR-----LRSDCFYEQPDEDGTLGF-RAAHIMVKEYMIQFNRLVAEFLVGSECTRT 979
             LR+ R     LR D        D   G  +  HI   EY  + N+LV EF++ +     
Sbjct: 538  QLRQQRFVDGALRLDQLKLAFTLDHETGLPQGCHIY--EYR-ESNKLVEEFMLLAN---- 590

Query: 980  VTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGGGGSPPDTRLHLLASLWKQVQF 1039
                            A+  K     P    L  H       PP TR+     L   V+F
Sbjct: 591  ---------------MAVAHKIHRAFPEQALLRRH------PPPQTRM-----LSDLVEF 624

Query: 1040 AARTQDYEQM---VDLVTTDDMHPFLAPAGRDLRKALERSAF--GRCARGHQQ------- 1087
                   +QM   VD  +   ++  L     D + +L R       C+R  Q        
Sbjct: 625  C------DQMGLPVDFSSAGALNKSLTQTFGDDKYSLARKEVLTNMCSRPMQMALYFCSG 678

Query: 1088 ------QGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARD-IDGLCQA 1140
                  Q  HY+L V  YT  TSPIRR+ DV++ R +  ALG+      A D +      
Sbjct: 679  LLQDPAQFRHYALNVPLYTHFTSPIRRFADVLVHRLLAAALGYRERLDMAPDTLQKQADH 738

Query: 1141 FSLQHALAQSYQRRARSLHLAVQLK-AQPLDKLGFVVDV 1178
             + +   ++  Q  + SL  AV +K + PL+    V+ +
Sbjct: 739  CNDRRMASKRVQELSTSLFFAVLVKESGPLESEAMVMGI 777


>gi|122937299 DNA replication helicase 2 homolog [Homo sapiens]
          Length = 1146

 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 93/348 (26%), Positives = 155/348 (44%), Gaps = 43/348 (12%)

Query: 1742 FSREDLVWYKKVLWEARKFELDRHEVILCTCSCAASA---SLKILDVRQILVDEAGMATE 1798
            F+ +++   K +   A   EL   ++I+ T     +    S KI D    +VDEA   ++
Sbjct: 798  FTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDF--CIVDEASQISQ 855

Query: 1799 PETLIPLVQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHEDAH---MLDTQ 1855
            P  L PL     + + VL+GDH+QL P+V N   + LG+  SLF+R  ++      L  Q
Sbjct: 856  PICLGPLFF---SRRFVLVGDHQQLPPLVLNREARALGMSESLFKRLEQNKSAVVQLTVQ 912

Query: 1856 YRMHEGICAFPSVAFYKSKLKTWQ--------GLRRPPSVL----GHAGKESCPVIFGHV 1903
            YRM+  I +  +   Y+ KL+            LR    V      +A     P + G  
Sbjct: 913  YRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLMGVF 972

Query: 1904 QGHERSLLVSTD------EGNENSKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNA 1957
            + +     ++TD      +  +   +N+ E   +V +T  + +     P DI ++ PY  
Sbjct: 973  EPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLT-SIFVKAGCSPSDIGIIAPYRQ 1031

Query: 1958 QASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLG 2017
            Q   I+  L R  I  V V+++ K QG +   VLVS VR+     + +   K W      
Sbjct: 1032 QLKIINDLLAR-SIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGEL-LKDW------ 1083

Query: 2018 FVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLV 2065
                  ++NVA+TRA+  L L+G    L C P    LL+   +++ ++
Sbjct: 1084 -----RRLNVAITRAKHKLILLGCVPSLNCYPPLEKLLNHLNSEKLII 1126



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 68/317 (21%), Positives = 127/317 (40%), Gaps = 44/317 (13%)

Query: 68   ELARHRVVVTTTSQARELRVPV---GFFSHILIDEAAQMLECEALTPLAYASHGTRLVLA 124
            EL   +++V TT     +  P+     F   ++DEA+Q+ +   L PL ++    R VL 
Sbjct: 817  ELYNSQLIVATTCMG--INHPIFSRKIFDFCIVDEASQISQPICLGPLFFSR---RFVLV 871

Query: 125  GDHMQVTPRLFS-VARARAAEHTLLHR----------LFLCYQQETHEVARQSRLVFHEN 173
            GDH Q+ P + +  ARA     +L  R          L + Y+  +  ++  ++L +   
Sbjct: 872  GDHQQLPPLVLNREARALGMSESLFKRLEQNKSAVVQLTVQYRMNSKIMSLSNKLTYEGK 931

Query: 174  YRC-----TDAIVSF-------ISRHFYVAKGNPIHARGKVPPHPRHYPLMFCHVAGSPD 221
              C      +A+++        +   FY    +     G   P   + P+ F +    P 
Sbjct: 932  LECGSDKVANAVINLRHFKDVKLELEFYADYSDNPWLMGVFEP---NNPVCFLNTDKVPA 988

Query: 222  RDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGAQVSALRQELRRRD 281
             +      +    ++ V E     + T      G     I +++   Q   +  +L  R 
Sbjct: 989  PEQ-----VEKGGVSNVTEAKLIVFLTSIFVKAGCSPSDIGIIAPYRQQLKIINDLLARS 1043

Query: 282  LGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQLV 341
            +G V V + +   GR   +V++S V +     +      E   D R LN  +TRA+ +L+
Sbjct: 1044 IGMVEVNTVDKYQGRDKSIVLVSFVRS-----NKDGTVGELLKDWRRLNVAITRAKHKLI 1098

Query: 342  VVGDAVALCSFGACGKL 358
            ++G   +L  +    KL
Sbjct: 1099 LLGCVPSLNCYPPLEKL 1115


>gi|28626521 zinc finger, NFX1-type containing 1 [Homo sapiens]
          Length = 1918

 Score = 79.0 bits (193), Expect = 5e-14
 Identities = 84/300 (28%), Positives = 135/300 (45%), Gaps = 37/300 (12%)

Query: 1780 LKILDVRQILVDEAGMATEPETLIPLVQFPQAEKVVLLGDHKQLRPVVKNERL-QNLGLD 1838
            L+ ++ R ++V+EA    E  T+  L +    + ++L+GDH+QLRP      L +N  L+
Sbjct: 995  LQKVEPRIVIVEEAAEVLEAHTIATLSK--ACQHLILIGDHQQLRPSANVYDLAKNFNLE 1052

Query: 1839 RSLFERYHE---DAHMLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAGKE- 1894
             SLFER  +       L+ Q+RM   I    +   Y       Q L   PSVL +   + 
Sbjct: 1053 VSLFERLVKVNIPFVRLNYQHRMCPEIARLLTPHIY-------QDLENHPSVLKYEKIKG 1105

Query: 1895 -SCPVIFGHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGRTVEPQDIAVLT 1953
             S  + F      E+ +     EG   S  N  E   VV + K   L +   P  I +LT
Sbjct: 1106 VSSNLFFVEHNFPEQEI----QEGK--SHQNQHEAHFVVELCKYF-LCQEYLPSQITILT 1158

Query: 1954 PYNAQASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLK 2013
             Y  Q   + K +  +  AGV V  + K QG E   +L+S VR+  +             
Sbjct: 1159 TYTGQLFCLRKLMPAKTFAGVRVHVVDKYQGEENDIILLSLVRSNQEGK----------- 1207

Query: 2014 KFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLVPAGQVRVC 2073
              +GF+   N++ VA++RA++G+  IG+  +L   PLW  ++        + P   +R+C
Sbjct: 1208 --VGFLQISNRICVALSRAKKGMYCIGNMQMLAKVPLWSKIIHTLRENNQIGP--MLRLC 1263



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 22/37 (59%), Positives = 27/37 (72%)

Query: 1583 KLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIV 1619
            KL+ SQ  A++ AL +   +IQGPPGTGKT VGL IV
Sbjct: 597  KLDDSQMEALQFALTRELAIIQGPPGTGKTYVGLKIV 633



 Score = 34.3 bits (77), Expect = 1.3
 Identities = 19/59 (32%), Positives = 34/59 (57%), Gaps = 4/59 (6%)

Query: 95   ILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTP--RLFSVARARAAEHTLLHRL 151
            ++++EAA++LE   +  L+ A     L+L GDH Q+ P   ++ +A+    E +L  RL
Sbjct: 1003 VIVEEAAEVLEAHTIATLSKACQ--HLILIGDHQQLRPSANVYDLAKNFNLEVSLFERL 1059


>gi|38788372 aquarius [Homo sapiens]
          Length = 1485

 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 79/304 (25%), Positives = 128/304 (42%), Gaps = 44/304 (14%)

Query: 1766 EVILCTCSCAASASLKILDVR----QILVDEAGMATEPETLIPLVQ------FPQAEKVV 1815
            ++I  TC+ AA     ++ +      IL++EA    E ET IPL+       F + ++ +
Sbjct: 1033 KIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFSRLKRWI 1092

Query: 1816 LLGDHKQLRPVVKNERLQNL-GLDRSLFERYHE---DAHMLDTQYRMHEGICAFPSVAFY 1871
            ++GDH QL PV+KN   Q    +++SLF R+         LD Q R    +C       Y
Sbjct: 1093 MIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLC-----NLY 1147

Query: 1872 KSKLKTWQGLRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANLEEVAEV 1931
              + K    L     +   +   +  +    +   E    V   E N     NL E   V
Sbjct: 1148 NWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVEDFQGVGESEPNPYFYQNLGEAEYV 1207

Query: 1932 VRITKQLTLGRTVEPQD-IAVLTPYNAQASEISKALRR----EGIAG--VAVSSITKSQG 1984
            V +   + L     P D I++LT YN Q   I   + R      + G    V+++ + QG
Sbjct: 1208 VALFMYMCL--LGYPADKISILTTYNGQKHLIRDIINRRCGNNPLIGRPNKVTTVDRFQG 1265

Query: 1985 SEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLL 2044
             +  Y+L+S VRT A                +G + D  ++ VA++RA+ GL +     L
Sbjct: 1266 QQNDYILLSLVRTRA----------------VGHLRDVRRLVVAMSRARLGLYIFARVSL 1309

Query: 2045 LRCC 2048
             + C
Sbjct: 1310 FQNC 1313



 Score = 34.7 bits (78), Expect = 1.0
 Identities = 16/43 (37%), Positives = 26/43 (60%)

Query: 1587 SQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQ 1629
            +Q  A+R  ++   T++ GPPGTGKT V + I+   + +  EQ
Sbjct: 805  TQIEAIRAGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNFPEQ 847


>gi|239757861 PREDICTED: similar to armadillo repeat containing,
            X-linked 4 [Homo sapiens]
          Length = 2382

 Score = 37.4 bits (85), Expect = 0.15
 Identities = 58/209 (27%), Positives = 83/209 (39%), Gaps = 26/209 (12%)

Query: 416  AEEQAAV---VTAMVKAEPGDEALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGACAA 472
            A E+A +   + A  KA  G    S     + +       A A AG   +     GA  A
Sbjct: 1865 AGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVGAEAGAGAEAGAGAEAGAGAGA-EA 1923

Query: 473  GAAAAAGVESTEAEDAEADFWPWDGELNADDAIL---RELLDESQKVMVTVGEDGLLDTV 529
            GA A AG  +    ++ A  W WDG+    ++ L    E   ES  +   VGED L    
Sbjct: 1924 GAEAGAGAGAGPGTESGAGVWSWDGDATTVESRLGAGEEAGVESWTLARNVGEDEL---- 1979

Query: 530  ARPESLQQARLYENLPPAALRKLLHAEPER---YRHCSFVPETFERASAIPLDDAS-SGP 585
            +R  S        ++   +LR L  AE E    +R  S    +FE  +    D+ S    
Sbjct: 1980 SRESS-------PDIEEISLRSLFWAESENSNTFRSKSGKDASFESGAG---DNTSIKDK 2029

Query: 586  IQVRGRLDCGMAF-AGDEVLVQLLSGDKA 613
             +  G +D G  F AG+E   +  S  KA
Sbjct: 2030 FEAAGGVDIGSWFCAGNENTSEDKSAPKA 2058


>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
          Length = 686

 Score = 37.0 bits (84), Expect = 0.20
 Identities = 45/149 (30%), Positives = 61/149 (40%), Gaps = 14/149 (9%)

Query: 351 SFGACGKLWESFIRECVERHSVCPEGLSMEQVEQGVAQRRRWPPRGTQAGA-AGNWEAAP 409
           S  A G++ +S   E     SV  EG   + VE G          G +AG  AG+   A 
Sbjct: 219 SVDAEGRVGDSVDAEGPAGDSVDAEGRVGDSVEAGDPAGD-----GVEAGVPAGDSVEAE 273

Query: 410 EPVGDLAEEQAAVVTAM-VKAEP---GDEALSPASRDITATTAQTEAAAAP---AGDAVK 462
            P GD  + +     A  V  EP   GD +LSP +  I     ++ A  +P   A DA +
Sbjct: 274 GPAGDSMDAEGPAGRARRVSGEPQQSGDGSLSPQAEAIEVAAGES-AGRSPGELAWDAAE 332

Query: 463 EDVVPGACAAGAAAAAGVESTEAEDAEAD 491
           E  VPG   +  AA     +   ED   D
Sbjct: 333 EAEVPGVKGSEEAAPGDARADAGEDRVGD 361



 Score = 31.6 bits (70), Expect = 8.5
 Identities = 36/113 (31%), Positives = 50/113 (44%), Gaps = 7/113 (6%)

Query: 384 QGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAE-EQAAVVTAMVKAEPGD--EALSPA- 439
           Q  A++R   P G+ +G AG+   A  P+GD  E E  A  +   +   GD  +A  PA 
Sbjct: 138 QEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVGDSVDAEGPAG 197

Query: 440 -SRDITATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGVESTEAEDAEAD 491
            S D          A  PAGD+V  +   G  +  A   AG +S +AE    D
Sbjct: 198 DSVDAEGPLGDNIQAEGPAGDSVDAEGRVGD-SVDAEGPAG-DSVDAEGRVGD 248


>gi|194248057 growth associated protein 43 isoform 1 [Homo sapiens]
          Length = 274

 Score = 35.8 bits (81), Expect = 0.45
 Identities = 31/118 (26%), Positives = 46/118 (38%), Gaps = 5/118 (4%)

Query: 374 PEGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPV----GDLAEEQAAV-VTAMVK 428
           P    +E+  +G       P  G++    G     P       GD A EQAA    A  +
Sbjct: 109 PVADGVEKKGEGTTTAEAAPATGSKPDEPGKAGETPSEEKKGEGDAATEQAAPQAPASSE 168

Query: 429 AEPGDEALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGVESTEAE 486
            + G      A++  T  +  ++A  APA +  K+  VP A  A AA     E   A+
Sbjct: 169 EKAGSAETESATKASTDNSPSSKAEDAPAKEEPKQADVPAAVTAAAATTPAAEDAAAK 226


>gi|4503911 growth associated protein 43 isoform 2 [Homo sapiens]
          Length = 238

 Score = 35.8 bits (81), Expect = 0.45
 Identities = 31/118 (26%), Positives = 46/118 (38%), Gaps = 5/118 (4%)

Query: 374 PEGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPV----GDLAEEQAAV-VTAMVK 428
           P    +E+  +G       P  G++    G     P       GD A EQAA    A  +
Sbjct: 73  PVADGVEKKGEGTTTAEAAPATGSKPDEPGKAGETPSEEKKGEGDAATEQAAPQAPASSE 132

Query: 429 AEPGDEALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGVESTEAE 486
            + G      A++  T  +  ++A  APA +  K+  VP A  A AA     E   A+
Sbjct: 133 EKAGSAETESATKASTDNSPSSKAEDAPAKEEPKQADVPAAVTAAAATTPAAEDAAAK 190


>gi|19913396 smoothelin isoform b [Homo sapiens]
          Length = 915

 Score = 35.0 bits (79), Expect = 0.77
 Identities = 28/95 (29%), Positives = 40/95 (42%), Gaps = 7/95 (7%)

Query: 375 EGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDE 434
           +GL+  ++EQ        P R  Q   A   +  P P G    +    VT +++A PG  
Sbjct: 146 KGLAAHRLEQCEV-----PEREEQEQQAEVSKPTPTPEG--TSQDVTTVTLLLRAPPGST 198

Query: 435 ALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGA 469
           + SPAS   + T A  E    PA        VPG+
Sbjct: 199 SSSPASPSSSPTPASPEPPLEPAEAQCLTAEVPGS 233


>gi|19913394 smoothelin isoform c [Homo sapiens]
          Length = 917

 Score = 35.0 bits (79), Expect = 0.77
 Identities = 28/95 (29%), Positives = 40/95 (42%), Gaps = 7/95 (7%)

Query: 375 EGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDE 434
           +GL+  ++EQ        P R  Q   A   +  P P G    +    VT +++A PG  
Sbjct: 146 KGLAAHRLEQCEV-----PEREEQEQQAEVSKPTPTPEG--TSQDVTTVTLLLRAPPGST 198

Query: 435 ALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGA 469
           + SPAS   + T A  E    PA        VPG+
Sbjct: 199 SSSPASPSSSPTPASPEPPLEPAEAQCLTAEVPGS 233


>gi|19913398 smoothelin isoform a [Homo sapiens]
          Length = 940

 Score = 35.0 bits (79), Expect = 0.77
 Identities = 28/95 (29%), Positives = 40/95 (42%), Gaps = 7/95 (7%)

Query: 375 EGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDE 434
           +GL+  ++EQ        P R  Q   A   +  P P G    +    VT +++A PG  
Sbjct: 146 KGLAAHRLEQCEV-----PEREEQEQQAEVSKPTPTPEG--TSQDVTTVTLLLRAPPGST 198

Query: 435 ALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGA 469
           + SPAS   + T A  E    PA        VPG+
Sbjct: 199 SSSPASPSSSPTPASPEPPLEPAEAQCLTAEVPGS 233


>gi|115527120 nebulin [Homo sapiens]
          Length = 6669

 Score = 34.3 bits (77), Expect = 1.3
 Identities = 27/104 (25%), Positives = 50/104 (48%), Gaps = 16/104 (15%)

Query: 1312 DTLQVQLGTSLQHGFLVPSPQLWTVAPGF----SLCLEHVERPGDCFSGRVYRAPRDRYR 1367
            D +Q +    LQ   +  S   W    G+    S+ +E V+R G+  S R YR P D+ +
Sbjct: 3611 DVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAGEILSDRKYRQPADQLK 3670

Query: 1368 DVDEYACVWEPFCALESATGAVAENDSVTL-QHL-SVSWEASRT 1409
                        C  ++    +A+N+++T+ +HL + +W+A +T
Sbjct: 3671 FT----------CITDTPEIVLAKNNALTMSKHLYTEAWDADKT 3704


>gi|30795231 brain abundant, membrane attached signal protein 1
           [Homo sapiens]
          Length = 227

 Score = 33.9 bits (76), Expect = 1.7
 Identities = 39/129 (30%), Positives = 55/129 (42%), Gaps = 13/129 (10%)

Query: 364 RECVERHSVCPEGLSMEQV-EQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAV 422
           +E  E+     EG + E+  E+  A  +   P+       G  EA  EP     +EQAA 
Sbjct: 52  KEGKEKPDQDAEGKAEEKEGEKDAAAAKEEAPKAEPEKTEGAAEAKAEPPKAPEQEQAA- 110

Query: 423 VTAMVKAEPGDEALSPASRDITATTAQTEAAAAPAG-DAVKEDVVPGACAAGAAAAAGVE 481
                   PG  A   A +   A  A  E+AA  AG +  KE+  P    A AA AA  +
Sbjct: 111 --------PGPAAGGEAPKAAEAAAAPAESAAPAAGEEPSKEEGEPKKTEAPAAPAA--Q 160

Query: 482 STEAEDAEA 490
            T+++ A A
Sbjct: 161 ETKSDGAPA 169



 Score = 33.5 bits (75), Expect = 2.2
 Identities = 29/105 (27%), Positives = 39/105 (37%), Gaps = 6/105 (5%)

Query: 384 QGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDEALSPASRDI 443
           +G A+ +  PP+     A    +AAP P     E   A   A   AE    A        
Sbjct: 91  EGAAEAKAEPPK-----APEQEQAAPGPAAG-GEAPKAAEAAAAPAESAAPAAGEEPSKE 144

Query: 444 TATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGVESTEAEDA 488
                +TEA AAPA    K D  P + +   ++ A   S E   A
Sbjct: 145 EGEPKKTEAPAAPAAQETKSDGAPASDSKPGSSEAAPSSKETPAA 189


>gi|24308527 stereocilin [Homo sapiens]
          Length = 1775

 Score = 33.9 bits (76), Expect = 1.7
 Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 21/103 (20%)

Query: 563  CSFVPETFERASAIPLDDASSGPIQVRGRLDCGMAFAGDEVLVQLLSGDKAPEGRLRGRV 622
            C   PE  E  S +PL D + GP++ RG L+C              +G  +PEGR+   +
Sbjct: 934  CFLSPE--ELQSLVPLSDPT-GPVE-RGLLECAA------------NGTLSPEGRVAYEL 977

Query: 623  LGVLKRKRHELAFVCRMDTWDPRIMVPINGSVTKIFVAELKDP 665
            LGVL+     +     +   + R+  P+   +   F+ EL +P
Sbjct: 978  LGVLRSSGGAV-----LSPRELRVWAPLFSQLGLRFLQELSEP 1015


>gi|169217788 PREDICTED: similar to putative DUX4 protein [Homo
            sapiens]
          Length = 422

 Score = 33.5 bits (75), Expect = 2.2
 Identities = 40/135 (29%), Positives = 55/135 (40%), Gaps = 28/135 (20%)

Query: 1441 IRLEGLPAPTASPRPGPSSL---GPGLNVDPGTY--TWVAHGQTQD-----WDQERRA-- 1488
            ++L+GLP P    +PGP+     G G+   P +    W   GQ        W+ +  A  
Sbjct: 272  LQLDGLPGPCTVGQPGPAQARPQGQGVLAIPASQGSPWWGWGQGPQVARAAWEPQAGAAP 331

Query: 1489 DRQEAPRRVHLFVHHMGMEKVPEEVLR-PG-------------TLFTVELLPKQLPDLRK 1534
             RQ AP     +   M    VP EVL+ PG              L + E L + LP L  
Sbjct: 332  PRQPAPPEASAWQGQMQGIPVPTEVLQEPGRSSALPSGLLLHELLVSQEFLQQGLPFLET 391

Query: 1535 EE--AVRGLEEASPL 1547
            E    +  LEEA+ L
Sbjct: 392  EAPGELEALEEAASL 406


>gi|7657455 pescadillo homolog 1, containing BRCT domain [Homo
           sapiens]
          Length = 588

 Score = 33.5 bits (75), Expect = 2.2
 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 1/69 (1%)

Query: 448 AQTEAAAAPAGDAV-KEDVVPGACAAGAAAAAGVESTEAEDAEADFWPWDGELNADDAIL 506
           AQ EA A     A+  E  +    A  A+ A  V     E+AE D +P DGE++A +   
Sbjct: 254 AQAEAKAGEGTYALDSESCMEKLAALSASLARVVVPATEEEAEVDEFPTDGEMSAQEEDR 313

Query: 507 RELLDESQK 515
           R+ L+  +K
Sbjct: 314 RKELEAQEK 322


>gi|5031579 A-kinase anchor protein 8 [Homo sapiens]
          Length = 692

 Score = 33.5 bits (75), Expect = 2.2
 Identities = 31/98 (31%), Positives = 42/98 (42%), Gaps = 10/98 (10%)

Query: 403 GNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDEAL------SPASRDITATTAQTEAAAAP 456
           G    APE  G+ AE++    TA   ++P  E L         + +     A++EAA A 
Sbjct: 591 GEGAPAPESSGEPAEDEGPTDTAEAGSDPQAEQLLEEQVPCGTAHEKGVPKARSEAAEAG 650

Query: 457 AG----DAVKEDVVPGACAAGAAAAAGVESTEAEDAEA 490
            G     A  E        A AAA A VE T+AE  +A
Sbjct: 651 NGAETMAAEAESAQTRVAPAPAAADAEVEQTDAESKDA 688


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,650,354
Number of Sequences: 37866
Number of extensions: 4312711
Number of successful extensions: 12259
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 12022
Number of HSP's gapped (non-prelim): 179
length of query: 2080
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1962
effective length of database: 13,779,330
effective search space: 27035045460
effective search space used: 27035045460
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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