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Search of human proteins with 153946387
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153946387 WAP four-disulfide core domain 8 precursor [Homo
sapiens]
(241 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153946389 WAP four-disulfide core domain 8 precursor [Homo sa... 551 e-157
gi|153946387 WAP four-disulfide core domain 8 precursor [Homo sa... 551 e-157
gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP... 89 3e-18
gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP... 89 3e-18
gi|32307109 WAP four-disulfide core domain 3 precursor [Homo sap... 72 6e-13
gi|21717822 WAP four-disulfide core domain 5 precursor [Homo sap... 63 2e-10
gi|28212222 WFIKKN2 protein [Homo sapiens] 61 1e-09
gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and n... 60 2e-09
gi|145309328 papilin [Homo sapiens] 59 4e-09
gi|5730091 tissue factor pathway inhibitor 2 [Homo sapiens] 57 1e-08
gi|4502067 alpha-1-microglobulin/bikunin preproprotein [Homo sap... 55 5e-08
gi|189571689 serine protease inhibitor, Kunitz type, 3 [Homo sap... 54 1e-07
gi|41406055 amyloid beta A4 protein isoform b precursor [Homo sa... 53 3e-07
gi|4502167 amyloid beta A4 protein isoform a precursor [Homo sap... 53 3e-07
gi|209915573 amyloid beta A4 protein isoform f precursor [Homo s... 53 3e-07
gi|74027265 serine peptidase inhibitor, Kunitz type 1 isoform 2 ... 52 6e-07
gi|4504329 serine peptidase inhibitor, Kunitz type 1 isoform 2 p... 52 6e-07
gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform ... 52 6e-07
gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1 ... 52 6e-07
gi|5454114 tissue factor pathway inhibitor isoform a precursor [... 51 8e-07
gi|10863909 serine protease inhibitor, Kunitz type, 2 [Homo sapi... 51 1e-06
gi|20069858 WAP four-disulfide core domain 12 precursor [Homo sa... 50 1e-06
gi|56699495 WAP four-disulfide core domain 2 precursor [Homo sap... 49 3e-06
gi|32313599 serine peptidase inhibitor, Kunitz type 1 isoform 1 ... 49 3e-06
gi|4507065 secretory leukocyte peptidase inhibitor precursor [Ho... 49 4e-06
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 49 4e-06
gi|154759255 collagen, type XXVIII precursor [Homo sapiens] 48 9e-06
gi|119395746 Kallmann syndrome 1 protein precursor [Homo sapiens] 46 3e-05
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s... 45 6e-05
gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s... 45 6e-05
>gi|153946389 WAP four-disulfide core domain 8 precursor [Homo
sapiens]
Length = 241
Score = 551 bits (1420), Expect = e-157
Identities = 241/241 (100%), Positives = 241/241 (100%)
Query: 1 MWTVRTEGGHFPLHSPTFSWRNVAFLLLLSLALEWTSAMLTKKIKHKPGLCPKERLTCTT 60
MWTVRTEGGHFPLHSPTFSWRNVAFLLLLSLALEWTSAMLTKKIKHKPGLCPKERLTCTT
Sbjct: 1 MWTVRTEGGHFPLHSPTFSWRNVAFLLLLSLALEWTSAMLTKKIKHKPGLCPKERLTCTT 60
Query: 61 ELPDSCNTDFDCKEYQKCCFFACQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRC 120
ELPDSCNTDFDCKEYQKCCFFACQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRC
Sbjct: 61 ELPDSCNTDFDCKEYQKCCFFACQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRC 120
Query: 121 TPFKYRGCEGNANNFLNEDACRTACMLIVKDGQCPLFPFTERKECPPSCHSDIDCPQTDK 180
TPFKYRGCEGNANNFLNEDACRTACMLIVKDGQCPLFPFTERKECPPSCHSDIDCPQTDK
Sbjct: 121 TPFKYRGCEGNANNFLNEDACRTACMLIVKDGQCPLFPFTERKECPPSCHSDIDCPQTDK 180
Query: 181 CCESRCGFVCARAWTVKKGFCPRKPLLCTKIDKPKCLQDEECPLVEKCCSHCGLKCMDPR 240
CCESRCGFVCARAWTVKKGFCPRKPLLCTKIDKPKCLQDEECPLVEKCCSHCGLKCMDPR
Sbjct: 181 CCESRCGFVCARAWTVKKGFCPRKPLLCTKIDKPKCLQDEECPLVEKCCSHCGLKCMDPR 240
Query: 241 R 241
R
Sbjct: 241 R 241
>gi|153946387 WAP four-disulfide core domain 8 precursor [Homo
sapiens]
Length = 241
Score = 551 bits (1420), Expect = e-157
Identities = 241/241 (100%), Positives = 241/241 (100%)
Query: 1 MWTVRTEGGHFPLHSPTFSWRNVAFLLLLSLALEWTSAMLTKKIKHKPGLCPKERLTCTT 60
MWTVRTEGGHFPLHSPTFSWRNVAFLLLLSLALEWTSAMLTKKIKHKPGLCPKERLTCTT
Sbjct: 1 MWTVRTEGGHFPLHSPTFSWRNVAFLLLLSLALEWTSAMLTKKIKHKPGLCPKERLTCTT 60
Query: 61 ELPDSCNTDFDCKEYQKCCFFACQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRC 120
ELPDSCNTDFDCKEYQKCCFFACQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRC
Sbjct: 61 ELPDSCNTDFDCKEYQKCCFFACQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRC 120
Query: 121 TPFKYRGCEGNANNFLNEDACRTACMLIVKDGQCPLFPFTERKECPPSCHSDIDCPQTDK 180
TPFKYRGCEGNANNFLNEDACRTACMLIVKDGQCPLFPFTERKECPPSCHSDIDCPQTDK
Sbjct: 121 TPFKYRGCEGNANNFLNEDACRTACMLIVKDGQCPLFPFTERKECPPSCHSDIDCPQTDK 180
Query: 181 CCESRCGFVCARAWTVKKGFCPRKPLLCTKIDKPKCLQDEECPLVEKCCSHCGLKCMDPR 240
CCESRCGFVCARAWTVKKGFCPRKPLLCTKIDKPKCLQDEECPLVEKCCSHCGLKCMDPR
Sbjct: 181 CCESRCGFVCARAWTVKKGFCPRKPLLCTKIDKPKCLQDEECPLVEKCCSHCGLKCMDPR 240
Query: 241 R 241
R
Sbjct: 241 R 241
>gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP
domains 1 isoform 2 [Homo sapiens]
Length = 117
Score = 89.4 bits (220), Expect = 3e-18
Identities = 39/97 (40%), Positives = 53/97 (54%)
Query: 49 GLCPKERLTCTTELPDSCNTDFDCKEYQKCCFFACQKKCMDPFQEPCMLPVRHGNCNHEA 108
G CPK R C + D C D C++ +KCC F+C KKC+D Q+ C +P G C
Sbjct: 15 GRCPKIREECEFQERDVCTKDRQCQDNKKCCVFSCGKKCLDLKQDVCEMPKETGPCLAYF 74
Query: 109 QRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTAC 145
W +D K+ C+ F Y GC+GN NNF ++ C C
Sbjct: 75 LHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 111
Score = 33.5 bits (75), Expect = 0.17
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 1/41 (2%)
Query: 199 GFCPRKPLLCTKIDKPKCLQDEECPLVEKCC-SHCGLKCMD 238
G CP+ C ++ C +D +C +KCC CG KC+D
Sbjct: 15 GRCPKIREECEFQERDVCTKDRQCQDNKKCCVFSCGKKCLD 55
Score = 30.8 bits (68), Expect = 1.1
Identities = 19/54 (35%), Positives = 22/54 (40%), Gaps = 12/54 (22%)
Query: 141 CRTACMLIVKDGQCPLFPFTERKECP----PSCHSDIDCPQTDKCCESRCGFVC 190
C+TA L G+CP R+EC C D C KCC CG C
Sbjct: 8 CKTALSL----GRCPKI----REECEFQERDVCTKDRQCQDNKKCCVFSCGKKC 53
>gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP
domains 1 isoform 1 precursor [Homo sapiens]
Length = 133
Score = 89.0 bits (219), Expect = 3e-18
Identities = 39/98 (39%), Positives = 53/98 (54%)
Query: 48 PGLCPKERLTCTTELPDSCNTDFDCKEYQKCCFFACQKKCMDPFQEPCMLPVRHGNCNHE 107
P CPK R C + D C D C++ +KCC F+C KKC+D Q+ C +P G C
Sbjct: 30 PRRCPKIREECEFQERDVCTKDRQCQDNKKCCVFSCGKKCLDLKQDVCEMPKETGPCLAY 89
Query: 108 AQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTAC 145
W +D K+ C+ F Y GC+GN NNF ++ C C
Sbjct: 90 FLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 127
Score = 32.3 bits (72), Expect = 0.38
Identities = 14/39 (35%), Positives = 21/39 (53%), Gaps = 1/39 (2%)
Query: 201 CPRKPLLCTKIDKPKCLQDEECPLVEKCC-SHCGLKCMD 238
CP+ C ++ C +D +C +KCC CG KC+D
Sbjct: 33 CPKIREECEFQERDVCTKDRQCQDNKKCCVFSCGKKCLD 71
>gi|32307109 WAP four-disulfide core domain 3 precursor [Homo
sapiens]
Length = 231
Score = 71.6 bits (174), Expect = 6e-13
Identities = 64/228 (28%), Positives = 84/228 (36%), Gaps = 41/228 (17%)
Query: 25 FLLLLSLALEWTSAMLTKKIKHKPGLCPKERLTCTTELPDSCNTDFDCKEYQKCCFFACQ 84
FLL LAL + +T K G CP + C + C D C QKCC C
Sbjct: 7 FLLKALLALGSLESWITAGEHAKEGECPPHKNPCK----ELCQGDELCPAEQKCCTTGCG 62
Query: 85 KKCMD---PFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDAC 141
+ C D + C +R +C + C K G C
Sbjct: 63 RICRDIPKGRKRDCPRVIRKQSCLKRC------ITDETCPGVKKCCTLG----------C 106
Query: 142 RTACMLIVKD-------GQCPLFPFTERKECPPSCHSDIDCPQTDKCCESRCGFVC-ARA 193
+C++ + G+CP P C C D CPQ KCC + CG C
Sbjct: 107 NKSCVVPISKQKLAEFGGECPADPLP----CEELCDGDASCPQGHKCCSTGCGRTCLGDI 162
Query: 194 WTVKKGFCPRKPL-LCTKIDKPKCLQDEECPLVEKCC-SHCGLKCMDP 239
+ G CP+ + LC C+ DE C EKCC S CG C+ P
Sbjct: 163 EGGRGGDCPKVLVGLCI----VGCVMDENCQAGEKCCKSGCGRFCVPP 206
Score = 27.7 bits (60), Expect = 9.3
Identities = 10/29 (34%), Positives = 15/29 (51%)
Query: 66 CNTDFDCKEYQKCCFFACQKKCMDPFQEP 94
C D +C+ +KCC C + C+ P P
Sbjct: 182 CVMDENCQAGEKCCKSGCGRFCVPPVLPP 210
>gi|21717822 WAP four-disulfide core domain 5 precursor [Homo
sapiens]
Length = 123
Score = 63.2 bits (152), Expect = 2e-10
Identities = 34/93 (36%), Positives = 39/93 (41%), Gaps = 1/93 (1%)
Query: 150 KDGQCPLFPFTERKECPPSCHSDIDCPQTDKCCESRCGFVCARAWTVKKGFCPRKPLLCT 209
K G CP P C D CP T KCC C C +VK G CP L C
Sbjct: 30 KSGGCPPDDGPCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSCPEDQLRCL 89
Query: 210 KIDKPKCLQDEECPLVEKCC-SHCGLKCMDPRR 241
C +D +C ++CC S CG C DP R
Sbjct: 90 SPMNHLCHKDSDCSGKKRCCHSACGRDCRDPAR 122
Score = 48.9 bits (115), Expect = 4e-06
Identities = 41/168 (24%), Positives = 56/168 (33%), Gaps = 59/168 (35%)
Query: 26 LLLLSLALEWTS---AMLTKKIKHKPGLCPKERLTCTTELPDSCNTDFDCKEYQKCCFFA 82
LLLL L S A+ +K K G CP + C +PD C D C +KCC+ A
Sbjct: 6 LLLLGALLAVGSQLPAVFGRKKGEKSGGCPPDDGPCLLSVPDQCVEDSQCPLTRKCCYRA 65
Query: 83 CQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACR 142
C ++C+ + V+ G+C + R C N+
Sbjct: 66 CFRQCVP------RVSVKLGSCPEDQLR-----------------CLSPMNHL------- 95
Query: 143 TACMLIVKDGQCPLFPFTERKECPPSCHSDIDCPQTDKCCESRCGFVC 190
CH D DC +CC S CG C
Sbjct: 96 --------------------------CHKDSDCSGKKRCCHSACGRDC 117
Score = 47.4 bits (111), Expect = 1e-05
Identities = 17/48 (35%), Positives = 28/48 (58%)
Query: 43 KIKHKPGLCPKERLTCTTELPDSCNTDFDCKEYQKCCFFACQKKCMDP 90
++ K G CP+++L C + + C+ D DC ++CC AC + C DP
Sbjct: 73 RVSVKLGSCPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRDP 120
>gi|28212222 WFIKKN2 protein [Homo sapiens]
Length = 576
Score = 60.8 bits (146), Expect = 1e-09
Identities = 26/64 (40%), Positives = 33/64 (51%)
Query: 82 ACQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDAC 141
AC CM C LP G C A RW ++ + +C F Y GCEGN NNF + +AC
Sbjct: 373 ACMLACMSGPLAACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREAC 432
Query: 142 RTAC 145
+C
Sbjct: 433 EESC 436
Score = 48.9 bits (115), Expect = 4e-06
Identities = 20/52 (38%), Positives = 26/52 (50%)
Query: 95 CMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACM 146
C+ P +C E RWHFD + C F + C N N+F +AC ACM
Sbjct: 328 CLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACM 379
Score = 37.4 bits (85), Expect = 0.012
Identities = 27/78 (34%), Positives = 35/78 (44%), Gaps = 15/78 (19%)
Query: 20 WRNVAFLLLLSLALEWTSAMLT-KKIKHK-PGLCPKE---------RLTCTTELPDSCNT 68
W VA LLLL L L L I++ G+CP + + TC E C T
Sbjct: 13 WEQVAALLLLLLLLGVPPRSLALPPIRYSHAGICPNDMNPNLWVDAQSTCRRE----CET 68
Query: 69 DFDCKEYQKCCFFACQKK 86
D +C+ Y+KCC C K
Sbjct: 69 DQECETYEKCCPNVCGTK 86
Score = 30.8 bits (68), Expect = 1.1
Identities = 25/77 (32%), Positives = 30/77 (38%), Gaps = 9/77 (11%)
Query: 165 CPPSCHSDIDCPQTDKCCESRCG---FVCARAWTVKKGFCPRKPLLCTKIDKPKCLQD-E 220
C C +D +C +KCC + CG V AR VK P D CLQ
Sbjct: 62 CRRECETDQECETYEKCCPNVCGTKSCVAARYMDVKGKKGPVGMPKEATCDHFMCLQQGS 121
Query: 221 ECPL-----VEKCCSHC 232
EC + V KC C
Sbjct: 122 ECDIWDGQPVCKCKDRC 138
>gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and
netrin domain containing 1 precursor [Homo sapiens]
Length = 548
Score = 60.1 bits (144), Expect = 2e-09
Identities = 26/64 (40%), Positives = 34/64 (53%)
Query: 82 ACQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDAC 141
ACQ+ C + C+LP G C RW + +C PF Y GCEGN NNF + ++C
Sbjct: 346 ACQQACARGPGDACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESC 405
Query: 142 RTAC 145
AC
Sbjct: 406 EDAC 409
Score = 38.9 bits (89), Expect = 0.004
Identities = 15/35 (42%), Positives = 20/35 (57%)
Query: 111 WHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTAC 145
WH+D + C F RGC+G A F +AC+ AC
Sbjct: 317 WHYDPQRGGCMTFPARGCDGAARGFETYEACQQAC 351
Score = 33.5 bits (75), Expect = 0.17
Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 14/68 (20%)
Query: 26 LLLLSLALEWTS-AMLTKKIKHKPGLCPKE---------RLTCTTELPDSCNTDFDCKEY 75
LL L L L TS A L + PG+CP + + TC E C+ D DC
Sbjct: 7 LLPLLLLLRLTSGAGLLPGLGSHPGVCPNQLSPNLWVDAQSTCERE----CSRDQDCAAA 62
Query: 76 QKCCFFAC 83
+KCC C
Sbjct: 63 EKCCINVC 70
Score = 29.3 bits (64), Expect = 3.2
Identities = 10/23 (43%), Positives = 12/23 (52%)
Query: 165 CPPSCHSDIDCPQTDKCCESRCG 187
C C D DC +KCC + CG
Sbjct: 49 CERECSRDQDCAAAEKCCINVCG 71
Score = 27.7 bits (60), Expect = 9.3
Identities = 10/21 (47%), Positives = 15/21 (71%), Gaps = 1/21 (4%)
Query: 215 KCLQDEECPLVEKCCSH-CGL 234
+C +D++C EKCC + CGL
Sbjct: 52 ECSRDQDCAAAEKCCINVCGL 72
>gi|145309328 papilin [Homo sapiens]
Length = 1251
Score = 58.9 bits (141), Expect = 4e-09
Identities = 24/51 (47%), Positives = 31/51 (60%)
Query: 95 CMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTAC 145
C+LP HG+C A RW+F +C F Y GC GNANNF +E C ++C
Sbjct: 727 CLLPSAHGSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSSC 777
>gi|5730091 tissue factor pathway inhibitor 2 [Homo sapiens]
Length = 235
Score = 57.0 bits (136), Expect = 1e-08
Identities = 26/58 (44%), Positives = 33/58 (56%)
Query: 93 EPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLIVK 150
E C+LP+ +G C R+++D C F Y GCEGNANNF +AC AC I K
Sbjct: 34 EICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEK 91
Score = 50.1 bits (118), Expect = 2e-06
Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Query: 79 CFFACQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNE 138
C C K + F C P G C+ R++F+ + C F Y GC GN NNF++
Sbjct: 145 CMGFCAPKKIPSF---CYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSR 201
Query: 139 DACRTACMLIVK 150
+ C+ AC +K
Sbjct: 202 EDCKRACAKALK 213
>gi|4502067 alpha-1-microglobulin/bikunin preproprotein [Homo
sapiens]
Length = 352
Score = 55.1 bits (131), Expect = 5e-08
Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Query: 81 FACQKKCMDPFQE--PCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNE 138
F +K+C+ + C LP+ G C Q W FD +C F Y GC+GN N F +E
Sbjct: 271 FVTEKECLQTCRTVAACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSE 330
Query: 139 DACRTAC 145
CR C
Sbjct: 331 KECREYC 337
Score = 46.6 bits (109), Expect = 2e-05
Identities = 25/72 (34%), Positives = 34/72 (47%), Gaps = 6/72 (8%)
Query: 92 QEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNE----DACRT--AC 145
++ C L G C R+ ++ + C F+Y GC GN NNF+ E CRT AC
Sbjct: 228 EDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVAAC 287
Query: 146 MLIVKDGQCPLF 157
L + G C F
Sbjct: 288 NLPIVRGPCRAF 299
>gi|189571689 serine protease inhibitor, Kunitz type, 3 [Homo
sapiens]
Length = 89
Score = 53.9 bits (128), Expect = 1e-07
Identities = 21/51 (41%), Positives = 27/51 (52%)
Query: 95 CMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTAC 145
C P+ G C RW F+F+ C F Y GC GN+NNFL ++ C C
Sbjct: 36 CAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFC 86
>gi|41406055 amyloid beta A4 protein isoform b precursor [Homo
sapiens]
Length = 751
Score = 52.8 bits (125), Expect = 3e-07
Identities = 22/54 (40%), Positives = 26/54 (48%)
Query: 92 QEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTAC 145
+E C G C RW+FD +C PF Y GC GN NNF E+ C C
Sbjct: 288 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
>gi|4502167 amyloid beta A4 protein isoform a precursor [Homo
sapiens]
Length = 770
Score = 52.8 bits (125), Expect = 3e-07
Identities = 22/54 (40%), Positives = 26/54 (48%)
Query: 92 QEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTAC 145
+E C G C RW+FD +C PF Y GC GN NNF E+ C C
Sbjct: 288 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
>gi|209915573 amyloid beta A4 protein isoform f precursor [Homo
sapiens]
Length = 714
Score = 52.8 bits (125), Expect = 3e-07
Identities = 22/54 (40%), Positives = 26/54 (48%)
Query: 92 QEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTAC 145
+E C G C RW+FD +C PF Y GC GN NNF E+ C C
Sbjct: 232 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 285
>gi|74027265 serine peptidase inhibitor, Kunitz type 1 isoform 2
precursor [Homo sapiens]
Length = 513
Score = 51.6 bits (122), Expect = 6e-07
Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 16/113 (14%)
Query: 92 QEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLI--- 148
++ C+ + G C RW++D C F Y GC GN NN+L E+ C AC +
Sbjct: 247 EDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGP 306
Query: 149 -------VKDGQCPLFPFTERKECPPSCHSD--IDCPQTDKCCESRCGFVCAR 192
V G C F C C D ++C T C ++ C +
Sbjct: 307 SMERRHPVCSGTCQPTQF----RCSNGCCIDSFLECDDTPNCPDASDEAACEK 355
Score = 45.1 bits (105), Expect = 6e-05
Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 18/111 (16%)
Query: 49 GLCPKERLTC--TTELPDSCNTDFDCKEY-------QKCCFFACQKKCMDPFQEPCMLPV 99
G C L C T PD+ + + C++Y Q+ F + + C+D LP
Sbjct: 329 GCCIDSFLECDDTPNCPDASD-EAACEKYTSGFDELQRIHFPSDKGHCVD-------LPD 380
Query: 100 RHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLIVK 150
G C RW+++ + C F Y GC GN NNF E C +C I K
Sbjct: 381 T-GLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGISK 430
>gi|4504329 serine peptidase inhibitor, Kunitz type 1 isoform 2
precursor [Homo sapiens]
Length = 513
Score = 51.6 bits (122), Expect = 6e-07
Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 16/113 (14%)
Query: 92 QEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLI--- 148
++ C+ + G C RW++D C F Y GC GN NN+L E+ C AC +
Sbjct: 247 EDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGP 306
Query: 149 -------VKDGQCPLFPFTERKECPPSCHSD--IDCPQTDKCCESRCGFVCAR 192
V G C F C C D ++C T C ++ C +
Sbjct: 307 SMERRHPVCSGTCQPTQF----RCSNGCCIDSFLECDDTPNCPDASDEAACEK 355
Score = 45.1 bits (105), Expect = 6e-05
Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 18/111 (16%)
Query: 49 GLCPKERLTC--TTELPDSCNTDFDCKEY-------QKCCFFACQKKCMDPFQEPCMLPV 99
G C L C T PD+ + + C++Y Q+ F + + C+D LP
Sbjct: 329 GCCIDSFLECDDTPNCPDASD-EAACEKYTSGFDELQRIHFPSDKGHCVD-------LPD 380
Query: 100 RHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLIVK 150
G C RW+++ + C F Y GC GN NNF E C +C I K
Sbjct: 381 T-GLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGISK 430
>gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform 2
[Homo sapiens]
Length = 751
Score = 51.6 bits (122), Expect = 6e-07
Identities = 22/61 (36%), Positives = 27/61 (44%)
Query: 95 CMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLIVKDGQC 154
C G C RW+FD +C F Y GC GN NNF +ED C C ++
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPPTPL 369
Query: 155 P 155
P
Sbjct: 370 P 370
>gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1
[Homo sapiens]
Length = 763
Score = 51.6 bits (122), Expect = 6e-07
Identities = 22/61 (36%), Positives = 27/61 (44%)
Query: 95 CMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLIVKDGQC 154
C G C RW+FD +C F Y GC GN NNF +ED C C ++
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPPTPL 369
Query: 155 P 155
P
Sbjct: 370 P 370
>gi|5454114 tissue factor pathway inhibitor isoform a precursor
[Homo sapiens]
Length = 304
Score = 51.2 bits (121), Expect = 8e-07
Identities = 20/51 (39%), Positives = 28/51 (54%)
Query: 95 CMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTAC 145
C+ P G C R++++ +C PFKY GC GN NNF ++ C AC
Sbjct: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRAC 267
Score = 43.1 bits (100), Expect = 2e-04
Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 3/80 (3%)
Query: 95 CMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLIVKDGQC 154
C G C +R+ F+ +C F Y GCEGN N F + + C+ C +D
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC---TRDNAN 110
Query: 155 PLFPFTERKECPPSCHSDID 174
+ T ++E P C + D
Sbjct: 111 RIIKTTLQQEKPDFCFLEED 130
Score = 41.6 bits (96), Expect = 6e-04
Identities = 18/51 (35%), Positives = 25/51 (49%)
Query: 95 CMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTAC 145
C L G C R+ ++ + +C FKY GC GN NNF + C+ C
Sbjct: 125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNIC 175
>gi|10863909 serine protease inhibitor, Kunitz type, 2 [Homo
sapiens]
Length = 252
Score = 50.8 bits (120), Expect = 1e-06
Identities = 22/66 (33%), Positives = 32/66 (48%)
Query: 91 FQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLIVK 150
++E C G C RW+FD + C F Y GC GN N++ +E+AC C +
Sbjct: 129 YEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQE 188
Query: 151 DGQCPL 156
+ PL
Sbjct: 189 NPPLPL 194
Score = 46.6 bits (109), Expect = 2e-05
Identities = 17/57 (29%), Positives = 30/57 (52%)
Query: 95 CMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLIVKD 151
C++ G C RW ++ + C F Y GC+GN+NN+L ++ C C + ++
Sbjct: 38 CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTEN 94
>gi|20069858 WAP four-disulfide core domain 12 precursor [Homo
sapiens]
Length = 111
Score = 50.4 bits (119), Expect = 1e-06
Identities = 23/70 (32%), Positives = 38/70 (54%), Gaps = 3/70 (4%)
Query: 27 LLLSLALEWTSAMLTKKIKH---KPGLCPKERLTCTTELPDSCNTDFDCKEYQKCCFFAC 83
L+L ++L + + + +K K G+CP + + C P C+TD DC +KCC+ C
Sbjct: 7 LVLMVSLVLVTLVAVEGVKEGIEKAGVCPADNVRCFKSDPPQCHTDQDCLGERKCCYLHC 66
Query: 84 QKKCMDPFQE 93
KC+ P +E
Sbjct: 67 GFKCVIPVKE 76
Score = 46.6 bits (109), Expect = 2e-05
Identities = 20/44 (45%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 197 KKGFCPRKPLLCTKIDKPKCLQDEECPLVEKCC-SHCGLKCMDP 239
K G CP + C K D P+C D++C KCC HCG KC+ P
Sbjct: 30 KAGVCPADNVRCFKSDPPQCHTDQDCLGERKCCYLHCGFKCVIP 73
Score = 43.5 bits (101), Expect = 2e-04
Identities = 20/43 (46%), Positives = 21/43 (48%)
Query: 148 IVKDGQCPLFPFTERKECPPSCHSDIDCPQTDKCCESRCGFVC 190
I K G CP K PP CH+D DC KCC CGF C
Sbjct: 28 IEKAGVCPADNVRCFKSDPPQCHTDQDCLGERKCCYLHCGFKC 70
>gi|56699495 WAP four-disulfide core domain 2 precursor [Homo
sapiens]
Length = 124
Score = 49.3 bits (116), Expect = 3e-06
Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
Query: 150 KDGQCPLFPFTERKECPPSCHSDIDCPQTDKCCESRCGFVCARAWTVKKGFCPRKPLLCT 209
K G CP + C C SD +C KCC + C C+ K+G CP+ +
Sbjct: 32 KTGVCP--ELQADQNCTQECVSDSECADNLKCCSAGCATFCSLP-NDKEGSCPQVNINFP 88
Query: 210 KID--KPKCLQDEECPLVEKCCSH-CG-LKCMDP 239
++ + +C D +CP KCC + CG + C+ P
Sbjct: 89 QLGLCRDQCQVDSQCPGQMKCCRNGCGKVSCVTP 122
Score = 36.2 bits (82), Expect = 0.026
Identities = 20/52 (38%), Positives = 23/52 (44%), Gaps = 3/52 (5%)
Query: 141 CRTACMLIV-KDGQCPL--FPFTERKECPPSCHSDIDCPQTDKCCESRCGFV 189
C T C L K+G CP F + C C D CP KCC + CG V
Sbjct: 66 CATFCSLPNDKEGSCPQVNINFPQLGLCRDQCQVDSQCPGQMKCCRNGCGKV 117
>gi|32313599 serine peptidase inhibitor, Kunitz type 1 isoform 1
precursor [Homo sapiens]
Length = 529
Score = 49.3 bits (116), Expect = 3e-06
Identities = 20/54 (37%), Positives = 28/54 (51%)
Query: 92 QEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTAC 145
++ C+ + G C RW++D C F Y GC GN NN+L E+ C AC
Sbjct: 247 EDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC 300
Score = 45.1 bits (105), Expect = 6e-05
Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 18/111 (16%)
Query: 49 GLCPKERLTC--TTELPDSCNTDFDCKEY-------QKCCFFACQKKCMDPFQEPCMLPV 99
G C L C T PD+ + + C++Y Q+ F + + C+D LP
Sbjct: 345 GCCIDSFLECDDTPNCPDASD-EAACEKYTSGFDELQRIHFPSDKGHCVD-------LPD 396
Query: 100 RHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLIVK 150
G C RW+++ + C F Y GC GN NNF E C +C I K
Sbjct: 397 T-GLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGISK 446
>gi|4507065 secretory leukocyte peptidase inhibitor precursor [Homo
sapiens]
Length = 132
Score = 48.9 bits (115), Expect = 4e-06
Identities = 27/81 (33%), Positives = 32/81 (39%), Gaps = 8/81 (9%)
Query: 167 PSCHSDIDCPQTDKCCESRCGFVC------ARAWTVKKGFCPRKPLLCTKIDKPK-CLQD 219
P C SD CP +CC CG C K G CP C ++ P C D
Sbjct: 49 PECQSDWQCPGKKRCCPDTCGIKCLDPVDTPNPTRRKPGKCPVTYGQCLMLNPPNFCEMD 108
Query: 220 EECPLVEKCC-SHCGLKCMDP 239
+C KCC CG C+ P
Sbjct: 109 GQCKRDLKCCMGMCGKSCVSP 129
Score = 47.8 bits (112), Expect = 9e-06
Identities = 20/45 (44%), Positives = 28/45 (62%), Gaps = 2/45 (4%)
Query: 197 KKGFCP-RKPLLCTKIDKPKCLQDEECPLVEKCC-SHCGLKCMDP 239
K G CP +K C + KP+C D +CP ++CC CG+KC+DP
Sbjct: 31 KAGVCPPKKSAQCLRYKKPECQSDWQCPGKKRCCPDTCGIKCLDP 75
Score = 45.4 bits (106), Expect = 4e-05
Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 8/88 (9%)
Query: 25 FLLLLSLALEWTSAMLTKKIKHKPGLCP-KERLTCTTELPDSCNTDFDCKEYQKCCFFAC 83
FL+LL+L A+ K G+CP K+ C C +D+ C ++CC C
Sbjct: 9 FLVLLALGTLAPWAVEGSGKSFKAGVCPPKKSAQCLRYKKPECQSDWQCPGKKRCCPDTC 68
Query: 84 QKKCMDPF-------QEPCMLPVRHGNC 104
KC+DP ++P PV +G C
Sbjct: 69 GIKCLDPVDTPNPTRRKPGKCPVTYGQC 96
Score = 39.3 bits (90), Expect = 0.003
Identities = 18/47 (38%), Positives = 21/47 (44%), Gaps = 1/47 (2%)
Query: 45 KHKPGLCPKERLTCTT-ELPDSCNTDFDCKEYQKCCFFACQKKCMDP 90
+ KPG CP C P+ C D CK KCC C K C+ P
Sbjct: 83 RRKPGKCPVTYGQCLMLNPPNFCEMDGQCKRDLKCCMGMCGKSCVSP 129
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 48.9 bits (115), Expect = 4e-06
Identities = 22/56 (39%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 93 EPCMLPVRHGNCNHEAQRWHFDF---KNYRCTPFKYRGCEGNANNFLNEDACRTAC 145
+PC LP+ G+C RW+ C PF Y GC GNAN F +AC C
Sbjct: 2874 DPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRC 2929
>gi|154759255 collagen, type XXVIII precursor [Homo sapiens]
Length = 1125
Score = 47.8 bits (112), Expect = 9e-06
Identities = 19/60 (31%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Query: 88 MDPFQEP-CMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACM 146
+D ++P C+ ++ GNC RW++D + C F + GC G+ N F +E C+ C+
Sbjct: 1064 VDGAEDPRCLEALKPGNCGEYVVRWYYDKQVNSCARFWFSGCNGSGNRFNSEKECQETCI 1123
>gi|119395746 Kallmann syndrome 1 protein precursor [Homo sapiens]
Length = 680
Score = 45.8 bits (107), Expect = 3e-05
Identities = 42/144 (29%), Positives = 58/144 (40%), Gaps = 29/144 (20%)
Query: 72 CKEYQKCCFFACQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGN 131
C+ +++C KC++P +E L R C + F K+Y C CE
Sbjct: 77 CQNHKQC------SKCLEPCKESGDL--RKHQCQSFCEPL-FPKKSYECLT----SCE-- 121
Query: 132 ANNFLNEDACRTACMLIVKDGQCPLFPFTE--RKECPPSCHSDIDCPQTDKCCESRCGFV 189
FL +L+VK G CP C SC D +C KCC + CG
Sbjct: 122 ---FLKY-------ILLVKQGDCPAPEKASGFAAACVESCEVDNECSGVKKCCSNGCGHT 171
Query: 190 CARAWTVKKG--FCPRKPLLCTKI 211
C T+ KG PRK L T++
Sbjct: 172 CQVPKTLYKGVPLKPRKELRFTEL 195
Score = 32.3 bits (72), Expect = 0.38
Identities = 23/68 (33%), Positives = 30/68 (44%), Gaps = 4/68 (5%)
Query: 176 PQTDKCCESRCGFVCARAWTVKKGFCP--RKPLLCTKIDKPKCLQDEECPLVEKCCSH-C 232
P+ C + C F+ VK+G CP K C D EC V+KCCS+ C
Sbjct: 110 PKKSYECLTSCEFL-KYILLVKQGDCPAPEKASGFAAACVESCEVDNECSGVKKCCSNGC 168
Query: 233 GLKCMDPR 240
G C P+
Sbjct: 169 GHTCQVPK 176
Score = 28.9 bits (63), Expect = 4.2
Identities = 10/27 (37%), Positives = 13/27 (48%)
Query: 64 DSCNTDFDCKEYQKCCFFACQKKCMDP 90
+SC D +C +KCC C C P
Sbjct: 149 ESCEVDNECSGVKKCCSNGCGHTCQVP 175
>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
sapiens]
Length = 2971
Score = 45.1 bits (105), Expect = 6e-05
Identities = 18/51 (35%), Positives = 23/51 (45%)
Query: 95 CMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTAC 145
C LP G C +W++D C F Y GC GN N F ++ C C
Sbjct: 2906 CKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 2956
>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
sapiens]
Length = 3177
Score = 45.1 bits (105), Expect = 6e-05
Identities = 18/51 (35%), Positives = 23/51 (45%)
Query: 95 CMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTAC 145
C LP G C +W++D C F Y GC GN N F ++ C C
Sbjct: 3112 CKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 3162
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.140 0.515
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,038,240
Number of Sequences: 37866
Number of extensions: 603379
Number of successful extensions: 1764
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 79
Number of HSP's that attempted gapping in prelim test: 1554
Number of HSP's gapped (non-prelim): 255
length of query: 241
length of database: 18,247,518
effective HSP length: 99
effective length of query: 142
effective length of database: 14,498,784
effective search space: 2058827328
effective search space used: 2058827328
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.