APP 28280

Name: APP	Sequence: fasta or formatted (770aa)		NCBI GI: 4502167
Description: amyloid beta A4 protein isoform a precursor		Referenced in: Ankyrin Family Additional Brain Proteins PDZ Domain
Other entries for this name: alt prot [639aa] amyloid beta A4 protein isoform e precursor alt prot [714aa] amyloid beta A4 protein isoform f precursor alt prot [751aa] amyloid beta A4 protein isoform b precursor alt prot [695aa] amyloid beta A4 protein isoform c precursor
Composition: Amino acid Percentage Count Longest homopolymer A alanine 8.2 63 2 C cysteine 2.3 18 2 D aspartate 6.5 50 3 E glutamate 11.9 92 4 F phenylalanine 2.7 21 2 G glycine 4.9 38 2 H histidine 3.2 25 2 I isoleucine 3.1 24 2 K lysine 5.3 41 3 L leucine 7.3 56 4 M methionine 3.1 24 1 N asparagine 4.0 31 2 P proline 4.5 35 2 Q glutamine 4.7 36 2 R arginine 4.8 37 3 S serine 4.5 35 1 T threonine 6.5 50 7 V valine 8.4 65 2 W tryptophan 1.2 9 2 Y tyrosine 2.6 20 1			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 amyloid beta A4 protein isoform a precursor APP 0.969 amyloid beta A4 protein isoform b precursor APP 0.901 amyloid beta A4 protein isoform f precursor APP 0.816 amyloid beta A4 protein isoform c precursor APP 0.717 amyloid beta A4 protein isoform e precursor APLP2 0.468 amyloid beta (A4) precursor-like protein 2 isoform ... APLP2 0.466 amyloid beta (A4) precursor-like protein 2 isoform 1 ... APLP2 0.399 amyloid beta (A4) precursor-like protein 2 isoform ... APLP2 0.232 amyloid beta (A4) precursor-like protein 2 isoform ... APLP1 0.150 amyloid precursor-like protein 1 isoform 1 precursor... APLP1 0.149 amyloid precursor-like protein 1 isoform 2 precursor ... SPINT2 0.030 serine protease inhibitor, Kunitz type, 2 COL6A3 0.027 alpha 3 type VI collagen isoform 5 precursor COL6A3 0.027 alpha 3 type VI collagen isoform 1 precursor COL6A3 0.027 alpha 3 type VI collagen isoform 4 precursor SPINT3 0.027 serine protease inhibitor, Kunitz type, 3 SPINT1 0.027 serine peptidase inhibitor, Kunitz type 1 isoform 2 ... SPINT1 0.027 serine peptidase inhibitor, Kunitz type 1 isoform 2 p... TFPI 0.026 tissue factor pathway inhibitor isoform b precursor ... TFPI 0.026 tissue factor pathway inhibitor isoform a precursor [... SPINT1 0.025 serine peptidase inhibitor, Kunitz type 1 isoform 1 ... COL28A1 0.025 collagen, type XXVIII precursor SPINLW1 0.024 serine peptidase inhibitor-like, with Kunitz and WAP... SPINLW1 0.024 serine peptidase inhibitor-like, with Kunitz and WAP... COL7A1 0.023 alpha 1 type VII collagen precursor AMBP 0.023 alpha-1-microglobulin/bikunin preproprotein TFPI2 0.022 tissue factor pathway inhibitor 2 WFIKKN2 0.022 WFIKKN2 protein PAPLN 0.021 papilin MYT1L 0.021 myelin transcription factor 1-like Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.