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Search of human proteins with 153267418
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153267418 EDAR-associated death domain isoform A [Homo
sapiens]
(215 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153267418 EDAR-associated death domain isoform A [Homo sapiens] 458 e-129
gi|18152769 EDAR-associated death domain isoform B [Homo sapiens] 417 e-117
gi|7019561 thyrotropin-releasing hormone degrading enzyme [Homo ... 34 0.082
gi|12383051 transmembrane protein with EGF-like and two follista... 32 0.53
gi|7706091 bifunctional apoptosis regulator [Homo sapiens] 31 0.70
gi|169173140 PREDICTED: hypothetical protein LOC100131112 [Homo ... 31 0.91
gi|74271832 G protein-coupled receptor 155 isoform 9 [Homo sapiens] 31 0.91
gi|74271834 G protein-coupled receptor 155 isoform 10 [Homo sapi... 31 0.91
gi|27734865 unc-5 homolog C-like [Homo sapiens] 30 2.0
gi|226497734 RNA binding motif protein 19 [Homo sapiens] 29 2.6
gi|226497654 RNA binding motif protein 19 [Homo sapiens] 29 2.6
gi|226497574 RNA binding motif protein 19 [Homo sapiens] 29 2.6
gi|126090892 aggrecan isoform 2 precursor [Homo sapiens] 29 2.6
gi|126090883 aggrecan isoform 1 precursor [Homo sapiens] 29 2.6
gi|14589860 aspartate beta-hydroxylase isoform c [Homo sapiens] 28 4.5
gi|14589864 aspartate beta-hydroxylase isoform b [Homo sapiens] 28 4.5
gi|14589866 aspartate beta-hydroxylase isoform a [Homo sapiens] 28 4.5
gi|157266273 RANBP2-like and GRIP domain containing 1 [Homo sapi... 28 5.9
gi|118200331 RANBP2-like and GRIP domain containing 2 [Homo sapi... 28 5.9
gi|150456444 hypothetical protein LOC57578 [Homo sapiens] 28 5.9
gi|119874201 furry-like [Homo sapiens] 28 7.7
gi|18375673 regulator of nonsense transcripts 1 [Homo sapiens] 28 7.7
gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens] 28 7.7
>gi|153267418 EDAR-associated death domain isoform A [Homo sapiens]
Length = 215
Score = 458 bits (1179), Expect = e-129
Identities = 215/215 (100%), Positives = 215/215 (100%)
Query: 1 MGLRTTKQMGRGTKAPGHQEDHMVKEPVEDTDPSTLSFNMSDKYPIQDTELPKAEECDTI 60
MGLRTTKQMGRGTKAPGHQEDHMVKEPVEDTDPSTLSFNMSDKYPIQDTELPKAEECDTI
Sbjct: 1 MGLRTTKQMGRGTKAPGHQEDHMVKEPVEDTDPSTLSFNMSDKYPIQDTELPKAEECDTI 60
Query: 61 TLNCPRNSDMKNQGEENGFPDSTGDPLPEISKDNSCKENCTCSSCLLRAPTISDLLNDQD 120
TLNCPRNSDMKNQGEENGFPDSTGDPLPEISKDNSCKENCTCSSCLLRAPTISDLLNDQD
Sbjct: 61 TLNCPRNSDMKNQGEENGFPDSTGDPLPEISKDNSCKENCTCSSCLLRAPTISDLLNDQD 120
Query: 121 LLDVIRIKLDPCHPTVKNWRNFASKWGMSYDELCFLEQRPQSPTLEFLLRNSQRTVGQLM 180
LLDVIRIKLDPCHPTVKNWRNFASKWGMSYDELCFLEQRPQSPTLEFLLRNSQRTVGQLM
Sbjct: 121 LLDVIRIKLDPCHPTVKNWRNFASKWGMSYDELCFLEQRPQSPTLEFLLRNSQRTVGQLM 180
Query: 181 ELCRLYHRADVEKVLRRWVDEEWPKRERGDPSRHF 215
ELCRLYHRADVEKVLRRWVDEEWPKRERGDPSRHF
Sbjct: 181 ELCRLYHRADVEKVLRRWVDEEWPKRERGDPSRHF 215
>gi|18152769 EDAR-associated death domain isoform B [Homo sapiens]
Length = 205
Score = 417 bits (1072), Expect = e-117
Identities = 195/195 (100%), Positives = 195/195 (100%)
Query: 21 DHMVKEPVEDTDPSTLSFNMSDKYPIQDTELPKAEECDTITLNCPRNSDMKNQGEENGFP 80
DHMVKEPVEDTDPSTLSFNMSDKYPIQDTELPKAEECDTITLNCPRNSDMKNQGEENGFP
Sbjct: 11 DHMVKEPVEDTDPSTLSFNMSDKYPIQDTELPKAEECDTITLNCPRNSDMKNQGEENGFP 70
Query: 81 DSTGDPLPEISKDNSCKENCTCSSCLLRAPTISDLLNDQDLLDVIRIKLDPCHPTVKNWR 140
DSTGDPLPEISKDNSCKENCTCSSCLLRAPTISDLLNDQDLLDVIRIKLDPCHPTVKNWR
Sbjct: 71 DSTGDPLPEISKDNSCKENCTCSSCLLRAPTISDLLNDQDLLDVIRIKLDPCHPTVKNWR 130
Query: 141 NFASKWGMSYDELCFLEQRPQSPTLEFLLRNSQRTVGQLMELCRLYHRADVEKVLRRWVD 200
NFASKWGMSYDELCFLEQRPQSPTLEFLLRNSQRTVGQLMELCRLYHRADVEKVLRRWVD
Sbjct: 131 NFASKWGMSYDELCFLEQRPQSPTLEFLLRNSQRTVGQLMELCRLYHRADVEKVLRRWVD 190
Query: 201 EEWPKRERGDPSRHF 215
EEWPKRERGDPSRHF
Sbjct: 191 EEWPKRERGDPSRHF 205
>gi|7019561 thyrotropin-releasing hormone degrading enzyme [Homo
sapiens]
Length = 1024
Score = 34.3 bits (77), Expect = 0.082
Identities = 27/91 (29%), Positives = 39/91 (42%), Gaps = 8/91 (8%)
Query: 95 SCKENCTCSSCLLRAPTISDLLNDQDLLDVIRIKLDPCHPTVKNWRNFASKW---GMSYD 151
+C ++ + LL S+++ DQD +DVI H W+ F KW Y
Sbjct: 893 TCSDDRNLLNRLLNLSLNSEVVLDQDAIDVIIHVARNPHGRDLAWKFFRDKWKILNTRYG 952
Query: 152 ELCFLEQRPQSPTLEFLLRNSQRTVGQLMEL 182
E F+ + S EFL T G+L EL
Sbjct: 953 EALFMNSKLISGVTEFL-----NTEGELKEL 978
>gi|12383051 transmembrane protein with EGF-like and two
follistatin-like domains 2 [Homo sapiens]
Length = 374
Score = 31.6 bits (70), Expect = 0.53
Identities = 29/106 (27%), Positives = 44/106 (41%), Gaps = 11/106 (10%)
Query: 56 ECDTITLNCPRNSDMKNQGEENGFPDS---TGDPLPEISKDNSCKENCTCSSCLLRAPTI 112
EC C + S++ E + D+ +GD + E S + S KE TC C A
Sbjct: 113 ECYLRQAACKQQSEILVVSEGSCATDAGSGSGDGVHEGSGETSQKETSTCDICQFGAEC- 171
Query: 113 SDLLNDQDLLDVIRIKLDPCHPTVKNWRNFASKWGMSYDELCFLEQ 158
D+D DV + C T N+ + G SYD C +++
Sbjct: 172 -----DEDAEDVWCVCNIDCSQT--NFNPLCASDGKSYDNACQIKE 210
>gi|7706091 bifunctional apoptosis regulator [Homo sapiens]
Length = 450
Score = 31.2 bits (69), Expect = 0.70
Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 5/104 (4%)
Query: 111 TISDLLNDQDLLDVIRIKLDPCHPTVKNWRNFASKWG-MSYD---ELCFLEQRPQSPTLE 166
TI L D D++ LD PT K WR F K+ + Y E + T
Sbjct: 301 TICPLQEDSSGEDIVTKLLDLKEPTWKQWREFLVKYSFLPYQLIAEFAWDWLEVHYWTSR 360
Query: 167 FLLRNSQ-RTVGQLMELCRLYHRADVEKVLRRWVDEEWPKRERG 209
FL+ N+ +V +L R++ R++++ V +R W +G
Sbjct: 361 FLIINAMLLSVLELFSFWRIWSRSELKTVPQRMWSHFWKVSTQG 404
>gi|169173140 PREDICTED: hypothetical protein LOC100131112 [Homo
sapiens]
Length = 160
Score = 30.8 bits (68), Expect = 0.91
Identities = 25/79 (31%), Positives = 33/79 (41%), Gaps = 7/79 (8%)
Query: 50 ELPKAEECDTITLNCPRNSDMKNQGEENGFPDSTGD-PLPEISKDNSCKENCTCSSCLLR 108
+LP E C I+ M+ E FP T D L EI K+ K + L
Sbjct: 54 QLPSNEGCKQISWQAVSRPQMEFYSEAQMFPYRTQDVSLKEIMKEEGIKWS------LWT 107
Query: 109 APTISDLLNDQDLLDVIRI 127
AP +S L N Q V+R+
Sbjct: 108 APGLSGLQNKQQDCSVVRV 126
>gi|74271832 G protein-coupled receptor 155 isoform 9 [Homo sapiens]
Length = 870
Score = 30.8 bits (68), Expect = 0.91
Identities = 21/78 (26%), Positives = 34/78 (43%), Gaps = 3/78 (3%)
Query: 32 DPSTLSFNMSDKYPIQDTELPKAEECDTITLNCPR-NSDMKNQGEENGFPDSTGDP-LPE 89
+P +F S P+ + EL + +T +C N ++ E ST +P +P
Sbjct: 564 EPGNTAFEESPA-PVNEPELFTSSIPETSCCSCSMGNGELHCPSIEPIANTSTSEPVIPS 622
Query: 90 ISKDNSCKENCTCSSCLL 107
K+N C C SC+L
Sbjct: 623 FEKNNHCVSRCNSQSCIL 640
>gi|74271834 G protein-coupled receptor 155 isoform 10 [Homo
sapiens]
Length = 870
Score = 30.8 bits (68), Expect = 0.91
Identities = 21/78 (26%), Positives = 34/78 (43%), Gaps = 3/78 (3%)
Query: 32 DPSTLSFNMSDKYPIQDTELPKAEECDTITLNCPR-NSDMKNQGEENGFPDSTGDP-LPE 89
+P +F S P+ + EL + +T +C N ++ E ST +P +P
Sbjct: 564 EPGNTAFEESPA-PVNEPELFTSSIPETSCCSCSMGNGELHCPSIEPIANTSTSEPVIPS 622
Query: 90 ISKDNSCKENCTCSSCLL 107
K+N C C SC+L
Sbjct: 623 FEKNNHCVSRCNSQSCIL 640
>gi|27734865 unc-5 homolog C-like [Homo sapiens]
Length = 518
Score = 29.6 bits (65), Expect = 2.0
Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 120 DLLDVIRIKLDPCHPTVKNWRNFASKWGMSYDELCFLE-QRPQSPTLEFLLRNSQRTVGQ 178
+L + +R+ L+P T +WR AS G+ ++ FL QR + + L ++ +
Sbjct: 411 ELFEQLRMLLEPNSITGNDWRGLASHLGLCGMKIRFLSCQRSPAAAILELFEEQNGSLQE 470
Query: 179 LMELCRLYHRADVEKVLRRWV 199
L L + R D ++ ++
Sbjct: 471 LHYLMTVMERLDCASAIQNYL 491
>gi|226497734 RNA binding motif protein 19 [Homo sapiens]
Length = 960
Score = 29.3 bits (64), Expect = 2.6
Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 3/91 (3%)
Query: 21 DHMVKEPVEDTDPSTLSFNMSDKYPIQDTELPKAEECDTITLNCPRNSDMKNQGEENGFP 80
D++ + V+ S+ S+ + E +AEE D+ + D K G+E G P
Sbjct: 209 DYLKSKMVKAGSSSSSEEEESEDEAVHCDEGSEAEEEDSSATPVLQERDSKGAGQEQGMP 268
Query: 81 DSTGDP---LPEISKDNSCKENCTCSSCLLR 108
P E K + KE TC + LR
Sbjct: 269 AGKKRPPEARAETEKPANQKEPTTCHTVKLR 299
>gi|226497654 RNA binding motif protein 19 [Homo sapiens]
Length = 960
Score = 29.3 bits (64), Expect = 2.6
Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 3/91 (3%)
Query: 21 DHMVKEPVEDTDPSTLSFNMSDKYPIQDTELPKAEECDTITLNCPRNSDMKNQGEENGFP 80
D++ + V+ S+ S+ + E +AEE D+ + D K G+E G P
Sbjct: 209 DYLKSKMVKAGSSSSSEEEESEDEAVHCDEGSEAEEEDSSATPVLQERDSKGAGQEQGMP 268
Query: 81 DSTGDP---LPEISKDNSCKENCTCSSCLLR 108
P E K + KE TC + LR
Sbjct: 269 AGKKRPPEARAETEKPANQKEPTTCHTVKLR 299
>gi|226497574 RNA binding motif protein 19 [Homo sapiens]
Length = 960
Score = 29.3 bits (64), Expect = 2.6
Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 3/91 (3%)
Query: 21 DHMVKEPVEDTDPSTLSFNMSDKYPIQDTELPKAEECDTITLNCPRNSDMKNQGEENGFP 80
D++ + V+ S+ S+ + E +AEE D+ + D K G+E G P
Sbjct: 209 DYLKSKMVKAGSSSSSEEEESEDEAVHCDEGSEAEEEDSSATPVLQERDSKGAGQEQGMP 268
Query: 81 DSTGDP---LPEISKDNSCKENCTCSSCLLR 108
P E K + KE TC + LR
Sbjct: 269 AGKKRPPEARAETEKPANQKEPTTCHTVKLR 299
>gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]
Length = 2416
Score = 29.3 bits (64), Expect = 2.6
Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 10/69 (14%)
Query: 27 PVEDTDPSTLSFNMSDKYPIQD---------TELPKA-EECDTITLNCPRNSDMKNQGEE 76
P E+ PS F + +P ++ +E P A EE T + P +++ + GEE
Sbjct: 801 PSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEE 860
Query: 77 NGFPDSTGD 85
+G PD +GD
Sbjct: 861 SGAPDVSGD 869
>gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]
Length = 2317
Score = 29.3 bits (64), Expect = 2.6
Identities = 21/69 (30%), Positives = 34/69 (49%), Gaps = 10/69 (14%)
Query: 27 PVEDTDPSTLSFNMSDKYPIQD---------TELPKA-EECDTITLNCPRNSDMKNQGEE 76
P E+ PS F + +P ++ +E P A EE T + P +++ + GEE
Sbjct: 801 PSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEE 860
Query: 77 NGFPDSTGD 85
+G PD +GD
Sbjct: 861 SGAPDVSGD 869
>gi|14589860 aspartate beta-hydroxylase isoform c [Homo sapiens]
Length = 313
Score = 28.5 bits (62), Expect = 4.5
Identities = 20/77 (25%), Positives = 38/77 (49%), Gaps = 9/77 (11%)
Query: 19 QEDHMVKEPVEDTDPSTLSFNMSDKYPIQDTELPKAEE------CDTITLNCPRNSDMKN 72
QED EP ++ D ++ ++ D++ + E+ E +T++ +C N DM+
Sbjct: 171 QEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDC--NQDMEE 228
Query: 73 QGEENGFPDSTGDPLPE 89
E PDS+ +P+ E
Sbjct: 229 MMSEQENPDSS-EPVVE 244
>gi|14589864 aspartate beta-hydroxylase isoform b [Homo sapiens]
Length = 299
Score = 28.5 bits (62), Expect = 4.5
Identities = 20/77 (25%), Positives = 38/77 (49%), Gaps = 9/77 (11%)
Query: 19 QEDHMVKEPVEDTDPSTLSFNMSDKYPIQDTELPKAEE------CDTITLNCPRNSDMKN 72
QED EP ++ D ++ ++ D++ + E+ E +T++ +C N DM+
Sbjct: 157 QEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDC--NQDMEE 214
Query: 73 QGEENGFPDSTGDPLPE 89
E PDS+ +P+ E
Sbjct: 215 MMSEQENPDSS-EPVVE 230
>gi|14589866 aspartate beta-hydroxylase isoform a [Homo sapiens]
Length = 758
Score = 28.5 bits (62), Expect = 4.5
Identities = 20/77 (25%), Positives = 38/77 (49%), Gaps = 9/77 (11%)
Query: 19 QEDHMVKEPVEDTDPSTLSFNMSDKYPIQDTELPKAEE------CDTITLNCPRNSDMKN 72
QED EP ++ D ++ ++ D++ + E+ E +T++ +C N DM+
Sbjct: 171 QEDGPTGEPQQEDDEFLMATDVDDRFETLEPEVSHEETEHSYHVEETVSQDC--NQDMEE 228
Query: 73 QGEENGFPDSTGDPLPE 89
E PDS+ +P+ E
Sbjct: 229 MMSEQENPDSS-EPVVE 244
>gi|157266273 RANBP2-like and GRIP domain containing 1 [Homo sapiens]
Length = 1756
Score = 28.1 bits (61), Expect = 5.9
Identities = 19/76 (25%), Positives = 35/76 (46%)
Query: 24 VKEPVEDTDPSTLSFNMSDKYPIQDTELPKAEECDTITLNCPRNSDMKNQGEENGFPDST 83
V++ + D ST FN S K + ++ P ++ SD+ + E +G
Sbjct: 1270 VRKNIFRFDESTTGFNFSFKSALSLSKSPAKLNQSGTSVGTDEESDVTQEEERDGQYFEP 1329
Query: 84 GDPLPEISKDNSCKEN 99
PLP++ + +S +EN
Sbjct: 1330 VVPLPDLVEVSSGEEN 1345
>gi|118200331 RANBP2-like and GRIP domain containing 2 [Homo
sapiens]
Length = 1013
Score = 28.1 bits (61), Expect = 5.9
Identities = 19/76 (25%), Positives = 35/76 (46%)
Query: 24 VKEPVEDTDPSTLSFNMSDKYPIQDTELPKAEECDTITLNCPRNSDMKNQGEENGFPDST 83
V++ + D ST FN S K + ++ P ++ SD+ + E +G
Sbjct: 527 VRKNIFRFDESTTGFNFSFKSALSLSKSPAKLNQSGTSVGTDEESDVTQEEERDGQYFEP 586
Query: 84 GDPLPEISKDNSCKEN 99
PLP++ + +S +EN
Sbjct: 587 VVPLPDLVEVSSGEEN 602
>gi|150456444 hypothetical protein LOC57578 [Homo sapiens]
Length = 2458
Score = 28.1 bits (61), Expect = 5.9
Identities = 13/30 (43%), Positives = 20/30 (66%)
Query: 160 PQSPTLEFLLRNSQRTVGQLMELCRLYHRA 189
P S L F+++N+ T+ L+ELC L +RA
Sbjct: 2042 PFSKLLSFVIQNAVFTLAYLVELCGLCYRA 2071
>gi|119874201 furry-like [Homo sapiens]
Length = 3013
Score = 27.7 bits (60), Expect = 7.7
Identities = 26/82 (31%), Positives = 31/82 (37%), Gaps = 22/82 (26%)
Query: 72 NQGEENGFPDSTG------DPLPEISKDNSCKENCTCSSCLLRAPTISDLLNDQD----- 120
NQGE FP + G D +PE S C + LL +DL+ D
Sbjct: 1562 NQGEPLPFPPAGGCWSPLVDYVPETSSPGLPLHRCNIAVILL-----TDLIIDHSVKVEW 1616
Query: 121 ------LLDVIRIKLDPCHPTV 136
LL I I D CHP V
Sbjct: 1617 GSYLHLLLHAIFIGFDHCHPEV 1638
>gi|18375673 regulator of nonsense transcripts 1 [Homo sapiens]
Length = 1118
Score = 27.7 bits (60), Expect = 7.7
Identities = 29/111 (26%), Positives = 49/111 (44%), Gaps = 14/111 (12%)
Query: 99 NCTCSSCLLRA--PTISDLLNDQDLLDVIRIKLDPC--HPTVKNWRNFASKWGMSYDELC 154
NC C + L P +D + V+ + PC ++K+ +S+W + C
Sbjct: 185 NCGCRNVFLLGFIPAKADSV-------VVLLCRQPCASQSSLKDINWDSSQWQPLIQDRC 237
Query: 155 FLEQRPQSPTLEFLLRNSQRTVGQLMELCRLYHR---ADVEKVLRRWVDEE 202
FL + P+ + LR Q T Q+ +L L+ A +E + + VDEE
Sbjct: 238 FLSWLVKIPSEQEQLRARQITAQQINKLEELWKENPSATLEDLEKPGVDEE 288
>gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]
Length = 4116
Score = 27.7 bits (60), Expect = 7.7
Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
Query: 160 PQSPTLEFLLRNSQRTVGQLMELCRLYHRADVEKVLRRWVDE 201
P F LR+ R + ++ LC H DVEK +R W+ E
Sbjct: 2266 PSKSHYVFNLRDFSRVIQGVL-LCPHTHLQDVEKCIRLWIHE 2306
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,783,127
Number of Sequences: 37866
Number of extensions: 461627
Number of successful extensions: 1237
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 1227
Number of HSP's gapped (non-prelim): 29
length of query: 215
length of database: 18,247,518
effective HSP length: 98
effective length of query: 117
effective length of database: 14,536,650
effective search space: 1700788050
effective search space used: 1700788050
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.