Search of human proteins with 15208656

Search of human proteins with 15208656

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15208656 platelet-derived growth factor alpha isoform 2
preproprotein [Homo sapiens]
         (196 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|15208656 platelet-derived growth factor alpha isoform 2 prepr...   398   e-111
gi|77695917 platelet-derived growth factor alpha isoform 1 prepr...   392   e-110
gi|4505681 platelet-derived growth factor beta isoform 1 preprop...   147   7e-36
gi|15451786 platelet-derived growth factor beta isoform 2 prepro...   139   2e-33
gi|4507887 vascular endothelial growth factor B [Homo sapiens]         50   1e-06
gi|4758378 vascular endothelial growth factor D preproprotein [H...    46   2e-05
gi|20149543 placental growth factor, vascular endothelial growth...    45   4e-05
gi|4885653 vascular endothelial growth factor C preproprotein [H...    43   2e-04
gi|9994187 platelet-derived growth factor C precursor [Homo sapi...    40   0.001
gi|76781485 vascular endothelial growth factor A isoform f precu...    39   0.003
gi|76781484 vascular endothelial growth factor A isoform e precu...    39   0.003
gi|76781483 vascular endothelial growth factor A isoform d precu...    39   0.003
gi|76781482 vascular endothelial growth factor A isoform c precu...    39   0.003
gi|76781481 vascular endothelial growth factor A isoform b precu...    39   0.003
gi|76781480 vascular endothelial growth factor A isoform a precu...    39   0.003
gi|76781487 vascular endothelial growth factor A isoform g precu...    39   0.003
gi|13376808 platelet derived growth factor D isoform 1 precursor...    36   0.024
gi|15451921 platelet derived growth factor D isoform 2 precursor...    36   0.024
gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]                31   0.77 
gi|67003568 skin-specific protein 32 [Homo sapiens]                    30   1.0  
gi|34147456 TBC domain-containing protein kinase-like [Homo sapi...    29   2.9  
gi|32967514 neurofibromin 2 isoform 7 [Homo sapiens]                   28   6.5  
gi|32967254 neurofibromin 2 isoform 2 [Homo sapiens]                   28   6.5  
gi|32967266 neurofibromin 2 isoform 2 [Homo sapiens]                   28   6.5  
gi|32967264 neurofibromin 2 isoform 7 [Homo sapiens]                   28   6.5  
gi|32967262 neurofibromin 2 isoform 6 [Homo sapiens]                   28   6.5  
gi|32967260 neurofibromin 2 isoform 5 [Homo sapiens]                   28   6.5  
gi|32451486 neurofibromin 2 isoform 2 [Homo sapiens]                   28   6.5  
gi|4557795 neurofibromin 2 isoform 1 [Homo sapiens]                    28   6.5  
gi|11321571 slit homolog 3 [Homo sapiens]                              28   6.5  

>gi|15208656 platelet-derived growth factor alpha isoform 2
           preproprotein [Homo sapiens]
          Length = 196

 Score =  398 bits (1023), Expect = e-111
 Identities = 196/196 (100%), Positives = 196/196 (100%)

Query: 1   MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLD 60
           MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLD
Sbjct: 1   MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLD 60

Query: 61  TSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIW 120
           TSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIW
Sbjct: 61  TSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIW 120

Query: 121 PPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACA 180
           PPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACA
Sbjct: 121 PPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACA 180

Query: 181 TTSLNPDYREEDTDVR 196
           TTSLNPDYREEDTDVR
Sbjct: 181 TTSLNPDYREEDTDVR 196


>gi|77695917 platelet-derived growth factor alpha isoform 1
           preproprotein [Homo sapiens]
          Length = 211

 Score =  392 bits (1008), Expect = e-110
 Identities = 193/193 (100%), Positives = 193/193 (100%)

Query: 1   MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLD 60
           MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLD
Sbjct: 1   MRTLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLD 60

Query: 61  TSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIW 120
           TSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIW
Sbjct: 61  TSLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIYEIPRSQVDPTSANFLIW 120

Query: 121 PPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACA 180
           PPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACA
Sbjct: 121 PPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACA 180

Query: 181 TTSLNPDYREEDT 193
           TTSLNPDYREEDT
Sbjct: 181 TTSLNPDYREEDT 193


>gi|4505681 platelet-derived growth factor beta isoform 1
           preproprotein [Homo sapiens]
          Length = 241

 Score =  147 bits (370), Expect = 7e-36
 Identities = 83/183 (45%), Positives = 108/183 (59%), Gaps = 11/183 (6%)

Query: 7   LLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLDTSLRAH 66
           L L  C YL  V AE   IP E+ E L+   I S  DLQRLL  D  G ED  +  L   
Sbjct: 7   LFLSLCCYLRLVSAEGDPIPEELYEMLSDHSIRSFDDLQRLLHGDP-GEEDGAELDLNMT 65

Query: 67  GVHATKHVPEKRPLPIRRKRSI------EEAVPAVCKTRTVIYEIPRSQVDPTSANFLIW 120
             H+   +        R +RS+      E A+ A CKTRT ++EI R  +D T+ANFL+W
Sbjct: 66  RSHSGGELESLA----RGRRSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTNANFLVW 121

Query: 121 PPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACA 180
           PPCVEV+RC+GCCN  +V+C+P++V  R V+V K+E VRKKP  K+  V LE+HL C C 
Sbjct: 122 PPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKCE 181

Query: 181 TTS 183
           T +
Sbjct: 182 TVA 184


>gi|15451786 platelet-derived growth factor beta isoform 2
           preproprotein [Homo sapiens]
          Length = 226

 Score =  139 bits (349), Expect = 2e-33
 Identities = 75/165 (45%), Positives = 100/165 (60%), Gaps = 11/165 (6%)

Query: 25  IPREVIERLARSQIHSIRDLQRLLEIDSVGSEDSLDTSLRAHGVHATKHVPEKRPLPIRR 84
           IP E+ E L+   I S  DLQRLL  D  G ED  +  L     H+   +        R 
Sbjct: 10  IPEELYEMLSDHSIRSFDDLQRLLHGDP-GEEDGAELDLNMTRSHSGGELESLA----RG 64

Query: 85  KRSI------EEAVPAVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSV 138
           +RS+      E A+ A CKTRT ++EI R  +D T+ANFL+WPPCVEV+RC+GCCN  +V
Sbjct: 65  RRSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTNANFLVWPPCVEVQRCSGCCNNRNV 124

Query: 139 KCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACATTS 183
           +C+P++V  R V+V K+E VRKKP  K+  V LE+HL C C T +
Sbjct: 125 QCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKCETVA 169


>gi|4507887 vascular endothelial growth factor B [Homo sapiens]
          Length = 207

 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 27/86 (31%), Positives = 45/86 (52%), Gaps = 6/86 (6%)

Query: 94  AVCKTRTVIYEIPRSQVDPTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVA 153
           A C+ R V+  +   ++  T A  L+ P CV V+RC GCC    ++C P+  H   +++ 
Sbjct: 45  ATCQPREVVVPLT-VELMGTVAKQLV-PSCVTVQRCGGCCPDDGLECVPTGQHQVRMQIL 102

Query: 154 KVEYVRKKPKLKEVQVRLEEHLECAC 179
            + Y    P  +  ++ LEEH +C C
Sbjct: 103 MIRY----PSSQLGEMSLEEHSQCEC 124


>gi|4758378 vascular endothelial growth factor D preproprotein [Homo
           sapiens]
          Length = 354

 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 3/76 (3%)

Query: 114 SANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEY-VRKKPKLKEVQVRLE 172
           S N    PPCV V RC GCCN  S+ C  +   + S ++ ++   +   P+L  V V++ 
Sbjct: 127 STNTFFKPPCVNVFRCGGCCNEESLICMNTSTSYISKQLFEISVPLTSVPEL--VPVKVA 184

Query: 173 EHLECACATTSLNPDY 188
            H  C C  T+    Y
Sbjct: 185 NHTGCKCLPTAPRHPY 200


>gi|20149543 placental growth factor, vascular endothelial growth
           factor-related protein [Homo sapiens]
          Length = 170

 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 18/68 (26%), Positives = 34/68 (50%), Gaps = 3/68 (4%)

Query: 112 PTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRL 171
           P+    +  P CV + RCTGCC   ++ C P    + ++++ K   +R   +   V++  
Sbjct: 66  PSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTMQLLK---IRSGDRPSYVELTF 122

Query: 172 EEHLECAC 179
            +H+ C C
Sbjct: 123 SQHVRCEC 130


>gi|4885653 vascular endothelial growth factor C preproprotein [Homo
           sapiens]
          Length = 419

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 20/66 (30%), Positives = 30/66 (45%), Gaps = 1/66 (1%)

Query: 114 SANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEE 173
           + N    PPCV V RC GCCN+  ++C  +   + S  + ++  V      K V +    
Sbjct: 147 ATNTFFKPPCVSVYRCGGCCNSEGLQCMNTSTSYLSKTLFEIT-VPLSQGPKPVTISFAN 205

Query: 174 HLECAC 179
           H  C C
Sbjct: 206 HTSCRC 211


>gi|9994187 platelet-derived growth factor C precursor [Homo
           sapiens]
          Length = 345

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 26/70 (37%), Positives = 35/70 (50%), Gaps = 9/70 (12%)

Query: 118 LIWPPCVEVKRCTG---CC--NTSSVKCQPSRV---HHRSVKVAKVEYVRKKPKLKEVQV 169
           + WP C+ VKRC G   CC  N +  +C PS+V   +H  +++     VR   K     V
Sbjct: 269 IFWPGCLLVKRCGGNCACCLHNCNECQCVPSKVTKKYHEVLQLRPKTGVRGLHK-SLTDV 327

Query: 170 RLEEHLECAC 179
            LE H EC C
Sbjct: 328 ALEHHEECDC 337


>gi|76781485 vascular endothelial growth factor A isoform f
           precursor [Homo sapiens]
          Length = 327

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 12/45 (26%), Positives = 26/45 (57%)

Query: 112 PTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVE 156
           P    ++  P CV + RC GCCN   ++C P+   + ++++ +++
Sbjct: 246 PDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIK 290


>gi|76781484 vascular endothelial growth factor A isoform e
           precursor [Homo sapiens]
          Length = 354

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 12/45 (26%), Positives = 26/45 (57%)

Query: 112 PTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVE 156
           P    ++  P CV + RC GCCN   ++C P+   + ++++ +++
Sbjct: 246 PDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIK 290


>gi|76781483 vascular endothelial growth factor A isoform d
           precursor [Homo sapiens]
          Length = 371

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 12/45 (26%), Positives = 26/45 (57%)

Query: 112 PTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVE 156
           P    ++  P CV + RC GCCN   ++C P+   + ++++ +++
Sbjct: 246 PDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIK 290


>gi|76781482 vascular endothelial growth factor A isoform c
           precursor [Homo sapiens]
          Length = 389

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 12/45 (26%), Positives = 26/45 (57%)

Query: 112 PTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVE 156
           P    ++  P CV + RC GCCN   ++C P+   + ++++ +++
Sbjct: 246 PDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIK 290


>gi|76781481 vascular endothelial growth factor A isoform b
           precursor [Homo sapiens]
          Length = 395

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 12/45 (26%), Positives = 26/45 (57%)

Query: 112 PTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVE 156
           P    ++  P CV + RC GCCN   ++C P+   + ++++ +++
Sbjct: 246 PDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIK 290


>gi|76781480 vascular endothelial growth factor A isoform a
           precursor [Homo sapiens]
          Length = 412

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 12/45 (26%), Positives = 26/45 (57%)

Query: 112 PTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVE 156
           P    ++  P CV + RC GCCN   ++C P+   + ++++ +++
Sbjct: 246 PDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIK 290


>gi|76781487 vascular endothelial growth factor A isoform g
           precursor [Homo sapiens]
          Length = 371

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 12/45 (26%), Positives = 26/45 (57%)

Query: 112 PTSANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVE 156
           P    ++  P CV + RC GCCN   ++C P+   + ++++ +++
Sbjct: 246 PDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIK 290


>gi|13376808 platelet derived growth factor D isoform 1 precursor
           [Homo sapiens]
          Length = 370

 Score = 35.8 bits (81), Expect = 0.024
 Identities = 22/82 (26%), Positives = 40/82 (48%), Gaps = 10/82 (12%)

Query: 115 ANFLIWPPCVEVKRCTGCC-----NTSSVKCQPSRVHHRSVKVAKVE--YVRKKPKLKE- 166
           AN + +P C+ V+RC G C     N  S  C   +   +  +V + E  +++++ + K  
Sbjct: 288 ANVVFFPRCLLVQRCGGNCGCGTVNWRSCTCNSGKTVKKYHEVLQFEPGHIKRRGRAKTM 347

Query: 167 --VQVRLEEHLECACATTSLNP 186
             V ++L+ H  C C  +S  P
Sbjct: 348 ALVDIQLDHHERCDCICSSRPP 369


>gi|15451921 platelet derived growth factor D isoform 2 precursor
           [Homo sapiens]
          Length = 364

 Score = 35.8 bits (81), Expect = 0.024
 Identities = 22/82 (26%), Positives = 40/82 (48%), Gaps = 10/82 (12%)

Query: 115 ANFLIWPPCVEVKRCTGCC-----NTSSVKCQPSRVHHRSVKVAKVE--YVRKKPKLKE- 166
           AN + +P C+ V+RC G C     N  S  C   +   +  +V + E  +++++ + K  
Sbjct: 282 ANVVFFPRCLLVQRCGGNCGCGTVNWRSCTCNSGKTVKKYHEVLQFEPGHIKRRGRAKTM 341

Query: 167 --VQVRLEEHLECACATTSLNP 186
             V ++L+ H  C C  +S  P
Sbjct: 342 ALVDIQLDHHERCDCICSSRPP 363


>gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]
          Length = 2303

 Score = 30.8 bits (68), Expect = 0.77
 Identities = 34/129 (26%), Positives = 53/129 (41%), Gaps = 13/129 (10%)

Query: 62   SLRAHGVHATKHVPEKRPLPIRRKRSIEEAVPAVCKTRTVIY---EIPRSQ----VDPTS 114
            S++  G   +   PEK     R  +     VPAV + RTVIY     PR+Q      P +
Sbjct: 1758 SVKTSGSPRSPAGPEKP----RGTQKTTPGVPAVLRGRTVIYVPSPAPRAQPKGTPGPRA 1813

Query: 115  ANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEH 174
                + PPC  + +        S   Q SR  HR  K +++  + + P+      RL + 
Sbjct: 1814 TPRKVAPPC--LAQPAAPAKVPSPGQQRSRSLHRPAKTSELATLSQPPRSATPPARLAKT 1871

Query: 175  LECACATTS 183
               + + TS
Sbjct: 1872 PSSSSSQTS 1880


>gi|67003568 skin-specific protein 32 [Homo sapiens]
          Length = 250

 Score = 30.4 bits (67), Expect = 1.0
 Identities = 20/76 (26%), Positives = 38/76 (50%), Gaps = 9/76 (11%)

Query: 93  PAVCKTRTVI-YEIP-RSQV-----DPTSANFLIWP-PCVEVKRCTGCCNTSSVKC-QPS 143
           PA C T+T + Y++P ++Q       P    ++ +P PC    +C   C T+ VKC  P 
Sbjct: 47  PAPCPTQTYVKYQVPCQTQTYVKCPAPCQRTYVKYPTPCQTYVKCPAPCQTTYVKCPTPC 106

Query: 144 RVHHRSVKVAKVEYVR 159
           + + +     ++ Y++
Sbjct: 107 QTYVKCPAPCQMTYIK 122


>gi|34147456 TBC domain-containing protein kinase-like [Homo
           sapiens]
          Length = 830

 Score = 28.9 bits (63), Expect = 2.9
 Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 2/72 (2%)

Query: 19  LAEEAEIPREVIERLARSQIHSIRDLQRLL-EIDSVGSEDSLDTSLRAHGVH-ATKHVPE 76
           L +  +I R   ERL     H  R L+ LL E   V     L   + A G+   T H+P 
Sbjct: 53  LCQYVDISRGKHERLVVVAEHCERSLEDLLRERKPVRYPSYLAPEVIAQGIFKTTDHMPS 112

Query: 77  KRPLPIRRKRSI 88
           K+PLP   K  +
Sbjct: 113 KKPLPSGPKSDV 124


>gi|32967514 neurofibromin 2 isoform 7 [Homo sapiens]
          Length = 507

 Score = 27.7 bits (60), Expect = 6.5
 Identities = 39/181 (21%), Positives = 78/181 (43%), Gaps = 8/181 (4%)

Query: 3   TLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDS---L 59
           T+A   L+     A +LAE+A+I  E  + LA+    + +++QR ++  ++ +E+    +
Sbjct: 285 TMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQR-IKATAIRTEEEKRLM 343

Query: 60  DTSLRAHGVHATKHVPE---KRPLPIRRKRSIEEAVPAVCKTRTVIYEI-PRSQVDPTSA 115
           +  +    V A K   E   +     + K+ ++EA  A  + +  + EI  +    P + 
Sbjct: 344 EQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNP 403

Query: 116 NFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHL 175
                PP +      G   +   K    +     ++  KVEY+ K   L+E    L+  +
Sbjct: 404 IPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEI 463

Query: 176 E 176
           E
Sbjct: 464 E 464


>gi|32967254 neurofibromin 2 isoform 2 [Homo sapiens]
          Length = 590

 Score = 27.7 bits (60), Expect = 6.5
 Identities = 39/181 (21%), Positives = 78/181 (43%), Gaps = 8/181 (4%)

Query: 3   TLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDS---L 59
           T+A   L+     A +LAE+A+I  E  + LA+    + +++QR ++  ++ +E+    +
Sbjct: 368 TMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQR-IKATAIRTEEEKRLM 426

Query: 60  DTSLRAHGVHATKHVPE---KRPLPIRRKRSIEEAVPAVCKTRTVIYEI-PRSQVDPTSA 115
           +  +    V A K   E   +     + K+ ++EA  A  + +  + EI  +    P + 
Sbjct: 427 EQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNP 486

Query: 116 NFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHL 175
                PP +      G   +   K    +     ++  KVEY+ K   L+E    L+  +
Sbjct: 487 IPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEI 546

Query: 176 E 176
           E
Sbjct: 547 E 547


>gi|32967266 neurofibromin 2 isoform 2 [Homo sapiens]
          Length = 590

 Score = 27.7 bits (60), Expect = 6.5
 Identities = 39/181 (21%), Positives = 78/181 (43%), Gaps = 8/181 (4%)

Query: 3   TLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDS---L 59
           T+A   L+     A +LAE+A+I  E  + LA+    + +++QR ++  ++ +E+    +
Sbjct: 368 TMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQR-IKATAIRTEEEKRLM 426

Query: 60  DTSLRAHGVHATKHVPE---KRPLPIRRKRSIEEAVPAVCKTRTVIYEI-PRSQVDPTSA 115
           +  +    V A K   E   +     + K+ ++EA  A  + +  + EI  +    P + 
Sbjct: 427 EQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNP 486

Query: 116 NFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHL 175
                PP +      G   +   K    +     ++  KVEY+ K   L+E    L+  +
Sbjct: 487 IPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEI 546

Query: 176 E 176
           E
Sbjct: 547 E 547


>gi|32967264 neurofibromin 2 isoform 7 [Homo sapiens]
          Length = 507

 Score = 27.7 bits (60), Expect = 6.5
 Identities = 39/181 (21%), Positives = 78/181 (43%), Gaps = 8/181 (4%)

Query: 3   TLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDS---L 59
           T+A   L+     A +LAE+A+I  E  + LA+    + +++QR ++  ++ +E+    +
Sbjct: 285 TMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQR-IKATAIRTEEEKRLM 343

Query: 60  DTSLRAHGVHATKHVPE---KRPLPIRRKRSIEEAVPAVCKTRTVIYEI-PRSQVDPTSA 115
           +  +    V A K   E   +     + K+ ++EA  A  + +  + EI  +    P + 
Sbjct: 344 EQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNP 403

Query: 116 NFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHL 175
                PP +      G   +   K    +     ++  KVEY+ K   L+E    L+  +
Sbjct: 404 IPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEI 463

Query: 176 E 176
           E
Sbjct: 464 E 464


>gi|32967262 neurofibromin 2 isoform 6 [Homo sapiens]
          Length = 549

 Score = 27.7 bits (60), Expect = 6.5
 Identities = 39/181 (21%), Positives = 78/181 (43%), Gaps = 8/181 (4%)

Query: 3   TLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDS---L 59
           T+A   L+     A +LAE+A+I  E  + LA+    + +++QR ++  ++ +E+    +
Sbjct: 327 TMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQR-IKATAIRTEEEKRLM 385

Query: 60  DTSLRAHGVHATKHVPE---KRPLPIRRKRSIEEAVPAVCKTRTVIYEI-PRSQVDPTSA 115
           +  +    V A K   E   +     + K+ ++EA  A  + +  + EI  +    P + 
Sbjct: 386 EQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNP 445

Query: 116 NFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHL 175
                PP +      G   +   K    +     ++  KVEY+ K   L+E    L+  +
Sbjct: 446 IPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEI 505

Query: 176 E 176
           E
Sbjct: 506 E 506


>gi|32967260 neurofibromin 2 isoform 5 [Homo sapiens]
          Length = 548

 Score = 27.7 bits (60), Expect = 6.5
 Identities = 39/181 (21%), Positives = 78/181 (43%), Gaps = 8/181 (4%)

Query: 3   TLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDS---L 59
           T+A   L+     A +LAE+A+I  E  + LA+    + +++QR ++  ++ +E+    +
Sbjct: 326 TMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQR-IKATAIRTEEEKRLM 384

Query: 60  DTSLRAHGVHATKHVPE---KRPLPIRRKRSIEEAVPAVCKTRTVIYEI-PRSQVDPTSA 115
           +  +    V A K   E   +     + K+ ++EA  A  + +  + EI  +    P + 
Sbjct: 385 EQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNP 444

Query: 116 NFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHL 175
                PP +      G   +   K    +     ++  KVEY+ K   L+E    L+  +
Sbjct: 445 IPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEI 504

Query: 176 E 176
           E
Sbjct: 505 E 505


>gi|32451486 neurofibromin 2 isoform 2 [Homo sapiens]
          Length = 590

 Score = 27.7 bits (60), Expect = 6.5
 Identities = 39/181 (21%), Positives = 78/181 (43%), Gaps = 8/181 (4%)

Query: 3   TLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDS---L 59
           T+A   L+     A +LAE+A+I  E  + LA+    + +++QR ++  ++ +E+    +
Sbjct: 368 TMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQR-IKATAIRTEEEKRLM 426

Query: 60  DTSLRAHGVHATKHVPE---KRPLPIRRKRSIEEAVPAVCKTRTVIYEI-PRSQVDPTSA 115
           +  +    V A K   E   +     + K+ ++EA  A  + +  + EI  +    P + 
Sbjct: 427 EQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNP 486

Query: 116 NFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHL 175
                PP +      G   +   K    +     ++  KVEY+ K   L+E    L+  +
Sbjct: 487 IPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEI 546

Query: 176 E 176
           E
Sbjct: 547 E 547


>gi|4557795 neurofibromin 2 isoform 1 [Homo sapiens]
          Length = 595

 Score = 27.7 bits (60), Expect = 6.5
 Identities = 39/181 (21%), Positives = 78/181 (43%), Gaps = 8/181 (4%)

Query: 3   TLACLLLLGCGYLAHVLAEEAEIPREVIERLARSQIHSIRDLQRLLEIDSVGSEDS---L 59
           T+A   L+     A +LAE+A+I  E  + LA+    + +++QR ++  ++ +E+    +
Sbjct: 368 TMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQR-IKATAIRTEEEKRLM 426

Query: 60  DTSLRAHGVHATKHVPE---KRPLPIRRKRSIEEAVPAVCKTRTVIYEI-PRSQVDPTSA 115
           +  +    V A K   E   +     + K+ ++EA  A  + +  + EI  +    P + 
Sbjct: 427 EQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNP 486

Query: 116 NFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHL 175
                PP +      G   +   K    +     ++  KVEY+ K   L+E    L+  +
Sbjct: 487 IPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEI 546

Query: 176 E 176
           E
Sbjct: 547 E 547


>gi|11321571 slit homolog 3 [Homo sapiens]
          Length = 1523

 Score = 27.7 bits (60), Expect = 6.5
 Identities = 18/60 (30%), Positives = 23/60 (38%), Gaps = 9/60 (15%)

Query: 124  VEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVRLEEHLECACATTS 183
            V +  C G C      CQP+R   R       +YV +          +E HLEC C   S
Sbjct: 1473 VPIMECRGGCGPQC--CQPTRSKRR-------KYVFQCTDGSSFVEEVERHLECGCLACS 1523


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.133    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,832,958
Number of Sequences: 37866
Number of extensions: 331366
Number of successful extensions: 920
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 900
Number of HSP's gapped (non-prelim): 37
length of query: 196
length of database: 18,247,518
effective HSP length: 97
effective length of query: 99
effective length of database: 14,574,516
effective search space: 1442877084
effective search space used: 1442877084
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.