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Search of human proteins with 148886661
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148886661 exportin 4 [Homo sapiens]
(1151 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148886661 exportin 4 [Homo sapiens] 2259 0.0
gi|154448896 exportin 7 isoform c [Homo sapiens] 115 2e-25
gi|154448892 exportin 7 isoform b [Homo sapiens] 115 2e-25
gi|154448894 exportin 7 isoform a [Homo sapiens] 112 2e-24
gi|12597633 RAN binding protein 17 [Homo sapiens] 73 1e-12
gi|21071052 helicase-like transcription factor [Homo sapiens] 37 0.11
gi|21071054 helicase-like transcription factor [Homo sapiens] 37 0.11
gi|82659109 retinoblastoma-associated factor 600 [Homo sapiens] 37 0.11
gi|126032350 protein kinase, DNA-activated, catalytic polypeptid... 36 0.18
gi|13654237 protein kinase, DNA-activated, catalytic polypeptide... 36 0.18
gi|113430845 PREDICTED: similar to protein kinase, DNA-activated... 36 0.18
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof... 36 0.18
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof... 36 0.18
gi|46049063 exportin 6 [Homo sapiens] 36 0.18
gi|224831257 importin 13 [Homo sapiens] 33 1.6
gi|145309324 FH2 domain containing 1 [Homo sapiens] 32 4.5
>gi|148886661 exportin 4 [Homo sapiens]
Length = 1151
Score = 2259 bits (5853), Expect = 0.0
Identities = 1151/1151 (100%), Positives = 1151/1151 (100%)
Query: 1 MMAAALGPPEVIAQLENAAKVLMAPPSMVNNEQRQHAEHIFLSFRKSKSPFAVCKHILET 60
MMAAALGPPEVIAQLENAAKVLMAPPSMVNNEQRQHAEHIFLSFRKSKSPFAVCKHILET
Sbjct: 1 MMAAALGPPEVIAQLENAAKVLMAPPSMVNNEQRQHAEHIFLSFRKSKSPFAVCKHILET 60
Query: 61 SKVDYVLFQAATAIMEAVVREWILLEKGSIESLRTFLLTYVLQRPNLQKYVREQILLAVA 120
SKVDYVLFQAATAIMEAVVREWILLEKGSIESLRTFLLTYVLQRPNLQKYVREQILLAVA
Sbjct: 61 SKVDYVLFQAATAIMEAVVREWILLEKGSIESLRTFLLTYVLQRPNLQKYVREQILLAVA 120
Query: 121 VIVKRGSLDKSIDCKSIFHEVSQLISSGNPTVQTLACSILTALLSEFSSSSKTSNIGLSM 180
VIVKRGSLDKSIDCKSIFHEVSQLISSGNPTVQTLACSILTALLSEFSSSSKTSNIGLSM
Sbjct: 121 VIVKRGSLDKSIDCKSIFHEVSQLISSGNPTVQTLACSILTALLSEFSSSSKTSNIGLSM 180
Query: 181 EFHGNCKRVFQEEDLRQIFMLTVEVLQEFSRRENLNAQMSSVFQRYLALANQVLSWNFLP 240
EFHGNCKRVFQEEDLRQIFMLTVEVLQEFSRRENLNAQMSSVFQRYLALANQVLSWNFLP
Sbjct: 181 EFHGNCKRVFQEEDLRQIFMLTVEVLQEFSRRENLNAQMSSVFQRYLALANQVLSWNFLP 240
Query: 241 PNLGRHYIAMFESSQNVLLKPTESWRETLLDSRVMELFFTVHRKIREDSDMAQDSLQCLA 300
PNLGRHYIAMFESSQNVLLKPTESWRETLLDSRVMELFFTVHRKIREDSDMAQDSLQCLA
Sbjct: 241 PNLGRHYIAMFESSQNVLLKPTESWRETLLDSRVMELFFTVHRKIREDSDMAQDSLQCLA 300
Query: 301 QLASLHGPIFPDEGSQVDYLAHFIEGLLNTINGIEIEDSEAVGISSIISNLITVFPRNVL 360
QLASLHGPIFPDEGSQVDYLAHFIEGLLNTINGIEIEDSEAVGISSIISNLITVFPRNVL
Sbjct: 301 QLASLHGPIFPDEGSQVDYLAHFIEGLLNTINGIEIEDSEAVGISSIISNLITVFPRNVL 360
Query: 361 TAIPSELFSSFVNCLTHLTCSFGRSAALEEVLDKDDMVYMEAYDKLLESWLTLVQDDKHF 420
TAIPSELFSSFVNCLTHLTCSFGRSAALEEVLDKDDMVYMEAYDKLLESWLTLVQDDKHF
Sbjct: 361 TAIPSELFSSFVNCLTHLTCSFGRSAALEEVLDKDDMVYMEAYDKLLESWLTLVQDDKHF 420
Query: 421 HKGFFTQHAVQVFNSYIQCHLAAPDGTRNLTANGVASREEEEISELQEDDRDQFSDQLAS 480
HKGFFTQHAVQVFNSYIQCHLAAPDGTRNLTANGVASREEEEISELQEDDRDQFSDQLAS
Sbjct: 421 HKGFFTQHAVQVFNSYIQCHLAAPDGTRNLTANGVASREEEEISELQEDDRDQFSDQLAS 480
Query: 481 VGMLGRIAAEHCIPLLTSLLEERVTRLHGQLQRHQQQLLASPGSSTVDNKMLDDLYEDIH 540
VGMLGRIAAEHCIPLLTSLLEERVTRLHGQLQRHQQQLLASPGSSTVDNKMLDDLYEDIH
Sbjct: 481 VGMLGRIAAEHCIPLLTSLLEERVTRLHGQLQRHQQQLLASPGSSTVDNKMLDDLYEDIH 540
Query: 541 WLILVTGYLLADDTQGETPLIPPEIMEYSIKHSSEVDINTTLQILGSPGEKASSIPGYNR 600
WLILVTGYLLADDTQGETPLIPPEIMEYSIKHSSEVDINTTLQILGSPGEKASSIPGYNR
Sbjct: 541 WLILVTGYLLADDTQGETPLIPPEIMEYSIKHSSEVDINTTLQILGSPGEKASSIPGYNR 600
Query: 601 TDSVIRLLSAILRVSEVESRAIRADLTHLLSPQMGKDIVWFLKRWAKTYLLVDEKLYDQI 660
TDSVIRLLSAILRVSEVESRAIRADLTHLLSPQMGKDIVWFLKRWAKTYLLVDEKLYDQI
Sbjct: 601 TDSVIRLLSAILRVSEVESRAIRADLTHLLSPQMGKDIVWFLKRWAKTYLLVDEKLYDQI 660
Query: 661 SLPFSTAFGADTEGSQWIIGYLLQKVISNLSVWSSEQDLANDTVQLLVTLVERRERANLV 720
SLPFSTAFGADTEGSQWIIGYLLQKVISNLSVWSSEQDLANDTVQLLVTLVERRERANLV
Sbjct: 661 SLPFSTAFGADTEGSQWIIGYLLQKVISNLSVWSSEQDLANDTVQLLVTLVERRERANLV 720
Query: 721 IQCENWWNLAKQFASRSPPLNFLSSPVQRTLMKALVLGGFAHMDTETKQQYWTEVLQPLQ 780
IQCENWWNLAKQFASRSPPLNFLSSPVQRTLMKALVLGGFAHMDTETKQQYWTEVLQPLQ
Sbjct: 721 IQCENWWNLAKQFASRSPPLNFLSSPVQRTLMKALVLGGFAHMDTETKQQYWTEVLQPLQ 780
Query: 781 QRFLRVINQENFQQMCQQEEVKQEITATLEALCGIAEATQIDNVAILFNFLMDFLTNCIG 840
QRFLRVINQENFQQMCQQEEVKQEITATLEALCGIAEATQIDNVAILFNFLMDFLTNCIG
Sbjct: 781 QRFLRVINQENFQQMCQQEEVKQEITATLEALCGIAEATQIDNVAILFNFLMDFLTNCIG 840
Query: 841 LMEVYKNTPETVNLIIEVFVEVAHKQICYLGESKAMNLYEACLTLLQVYSKNNLGRQRID 900
LMEVYKNTPETVNLIIEVFVEVAHKQICYLGESKAMNLYEACLTLLQVYSKNNLGRQRID
Sbjct: 841 LMEVYKNTPETVNLIIEVFVEVAHKQICYLGESKAMNLYEACLTLLQVYSKNNLGRQRID 900
Query: 901 VTAEEEQYQDLLLIMELLTNLLSKEFIDFSDTDEVFRGHEPGQAANRSVSAADVVLYGVN 960
VTAEEEQYQDLLLIMELLTNLLSKEFIDFSDTDEVFRGHEPGQAANRSVSAADVVLYGVN
Sbjct: 901 VTAEEEQYQDLLLIMELLTNLLSKEFIDFSDTDEVFRGHEPGQAANRSVSAADVVLYGVN 960
Query: 961 LILPLMSQDLLKFPTLCNQYYKLITFICEIFPEKIPQLPEDLFKSLMYSLELGMTSMSSE 1020
LILPLMSQDLLKFPTLCNQYYKLITFICEIFPEKIPQLPEDLFKSLMYSLELGMTSMSSE
Sbjct: 961 LILPLMSQDLLKFPTLCNQYYKLITFICEIFPEKIPQLPEDLFKSLMYSLELGMTSMSSE 1020
Query: 1021 VCQLCLEALTPLAEQCAKAQETDSPLFLATRHFLKLVFDMLVLQKHNTEMTTAAGEAFYT 1080
VCQLCLEALTPLAEQCAKAQETDSPLFLATRHFLKLVFDMLVLQKHNTEMTTAAGEAFYT
Sbjct: 1021 VCQLCLEALTPLAEQCAKAQETDSPLFLATRHFLKLVFDMLVLQKHNTEMTTAAGEAFYT 1080
Query: 1081 LVCLHQAEYSELVETLLSSQQDPVIYQRLADAFNKLTASSTPPTLDRKQKMAFLKSLEEF 1140
LVCLHQAEYSELVETLLSSQQDPVIYQRLADAFNKLTASSTPPTLDRKQKMAFLKSLEEF
Sbjct: 1081 LVCLHQAEYSELVETLLSSQQDPVIYQRLADAFNKLTASSTPPTLDRKQKMAFLKSLEEF 1140
Query: 1141 MANVGGLLCVK 1151
MANVGGLLCVK
Sbjct: 1141 MANVGGLLCVK 1151
>gi|154448896 exportin 7 isoform c [Homo sapiens]
Length = 1088
Score = 115 bits (288), Expect = 2e-25
Identities = 231/1182 (19%), Positives = 450/1182 (38%), Gaps = 169/1182 (14%)
Query: 12 IAQLENAAKVLMAPPSMVNNEQRQHAEHIFLSFRKSKSPFAVCKHILETSKVDYVLFQAA 71
+AQLEN K L + R AE + F S + C+ +LE Y AA
Sbjct: 9 LAQLENLCKQLY---ETTDTTTRLQAEKALVEFTNSPDCLSKCQLLLERGSSSYSQLLAA 65
Query: 72 TAIMEAVVREWILLEKGSIESLRTFLLTYVLQRPNLQKYVREQILLAVAVIVKRGSLDKS 131
T + + V R L +R ++L Y+ RP L +V + ++ A I K G D
Sbjct: 66 TCLTKLVSRTNNPLPLEQRIDIRNYVLNYLATRPKLATFVTQALIQLYARITKLGWFDCQ 125
Query: 132 IDCKSIFHEVSQLISSGNPTVQTLACSILTALLSEFSSSSKTSNIGLSMEFHGNCKRVFQ 191
D + ++ + +V+ C I +LS+ ++ ++ + H F+
Sbjct: 126 KDDYVFRNAITDVTRFLQDSVE--YCIIGVTILSQLTNEINQADTTHPLTKHRKIASSFR 183
Query: 192 EEDLRQIFMLTVEVLQEFSRRE-NLNAQ-MSSVFQRYLALANQVLSWNFLPPNLGRHYIA 249
+ L IF L+ +L++ S + NLN + + + L L + L+++F+ +
Sbjct: 184 DSSLFDIFTLSCNLLKQASGKNLNLNDESQHGLLMQLLKLTHNCLNFDFIGTSTD----- 238
Query: 250 MFESSQNV-LLKPTESWRETLLDSRVMELFFTVHRKIREDSDMAQDSLQCLAQLASLHGP 308
ESS ++ ++ SWR LDS ++LFF ++ I + L CL Q+AS+
Sbjct: 239 --ESSDDLCTVQIPTSWRSAFLDSSTLQLFFDLYHSI--PPSFSPLVLSCLVQIASVRRS 294
Query: 309 IFPDEGSQVDYLAHFIEGLLNTI-NGIEIEDSEAVGISSIISNLITVFPRNVLTAIPSEL 367
+F + + +L+H ++G+ + N + D P N
Sbjct: 295 LF-NNAERAKFLSHLVDGVKRILENPQSLSD-----------------PNN--------- 327
Query: 368 FSSFVNCLTHLTCSFGRSAALEEVLDKDDMVYMEAYDKL--LESWLTLVQDDKHFHKGFF 425
+ F L L ++ + L +V + +++ + A + L+ W + H+ +
Sbjct: 328 YHEFCRLLARLKSNY-QLGELVKVENYPEVIRLIANFTVTSLQHW-EFAPNSVHYLLSLW 385
Query: 426 TQHAVQV-FNSYIQCHLAAPDGTRNLTANGVASREEEEISELQEDDRDQFSD------QL 478
+ A V + + H+ T +T + SR E L++ D D QL
Sbjct: 386 QRLAASVPYVKATEPHM-LETYTPEVTKAYITSRLESVHIILRDGLEDPLEDTGLVQQQL 444
Query: 479 ASVGMLGRIAAEHCIPLLTSLLEERVTRLHGQLQRHQQQLLASPGSSTVDNKMLDDLYED 538
+ +GR E LL L + Q + Q+LL S +S +D + +
Sbjct: 445 DQLSTIGRCEYEKTCALLVQLFD--------QSAQSYQELLQSASASPMDIAVQEG---R 493
Query: 539 IHWLILVTGYLLADDTQGETPLIPPEIMEYSIKHSSEVDINTTLQILGSPGEKASSIPGY 598
+ WL+ + G ++ V +T + GE
Sbjct: 494 LTWLVYIIGAVI----------------------GGRVSFASTDEQDAMDGE-------- 523
Query: 599 NRTDSVIRLLSAILRVSEVESRAIRADLTHLLSPQMGKDIVWFLKRWAKTYLLVDEKLYD 658
L+ +L++ + + L M F K + + KLY
Sbjct: 524 --------LVCRVLQLMNLTDSRLAQAGNEKLELAMLSFFEQFRKIYIGDQVQKSSKLYR 575
Query: 659 QISLPFSTAFGADTEGSQWIIGYLLQKVISNLSVWSSEQDLANDTVQLLVTL------VE 712
++ S G + E ++ + K+I+NL W + + + T+QLL L V
Sbjct: 576 RL----SEVLGLNDE--TMVLSVFIGKIITNLKYWGRCEPITSKTLQLLNDLSIGYSSVR 629
Query: 713 RRERANLV-IQCENWWNLAKQFASRSPPLNFLSSPVQRTLMKALVLGGFAHMDTETKQQY 771
+ + + V N + F + N + T A LG +D +
Sbjct: 630 KLVKLSAVQFMLNNHTSEHFSFLGINNQSNLTDMRCRTTFYTA--LGRLLMVDLGEDEDQ 687
Query: 772 WTEVLQPLQQRFLRVINQENFQQMCQQEEVKQEITATLEALCGIAEATQI-DNVAILFNF 830
+ + + PL F + Q ++E K+ + + L GIA A + +LF +
Sbjct: 688 YEQFMLPLTAAF-EAVAQMFSTNSFNEQEAKRTLVGLVRDLRGIAFAFNAKTSFMMLFEW 746
Query: 831 LM-DFLTNCIGLMEVYKNTPETVNLIIEVFVEVAHKQICYL----GESKAMNLYEACLTL 885
+ ++ +E++ + P ++++ E+ H + L + L+ +
Sbjct: 747 IYPSYMPILQRAIELWYHDPACTTPVLKLMAELVHNRSQRLQFDVSSPNGILLFRETSKM 806
Query: 886 LQVYSKNNLGRQRIDVTAEEEQY----QDLLLIMELLTNLLSKEFIDFSDTDEVFRGHEP 941
+ +Y L + +++ Y + + + +L LS +++F VFR +
Sbjct: 807 ITMYGNRIL---TLGEVPKDQVYALKLKGISICFSMLKAALSGSYVNFG----VFRLYGD 859
Query: 942 GQAANRSVSAADVVLYGVNLILPLMSQDLLKFPTLCNQYYKLITFICEIFPEKIPQLPED 1001
N + + L+L + DLL +P L YY L+ + + I L
Sbjct: 860 DALDN-------ALQTFIKLLLSIPHSDLLDYPKLSQSYYSLLEVLTQDHMNFIASLEPH 912
Query: 1002 LFKSLMYSLELGMTSMSSEVCQLCLEAL----TPLAEQCAKA---------QETDSPLFL 1048
+ ++ S+ G+T++ + VC C L T L +Q +++ QE+D L +
Sbjct: 913 VIMYILSSISEGLTALDTMVCTGCCSCLDHIVTYLFKQLSRSTKKRTTPLNQESDRFLHI 972
Query: 1049 ATRH------FLKLVFDMLVLQKHNTEMTTAAGEAFYTLVCLHQAEYSELVETLLSSQQD 1102
+H L V ++++ + + + + L+ L++ +S+L ++++S Q
Sbjct: 973 MQQHPEMIQQMLSTVLNIIIFEDCRNQWSMS--RPLLGLILLNEKYFSDLRNSIVNS-QP 1029
Query: 1103 PVIYQRLADAFNKLTASSTPPTLDRKQKMAFLKSLEEFMANV 1144
P Q + F L L K + F ++L F V
Sbjct: 1030 PEKQQAMHLCFENL-MEGIERNLLTKNRDRFTQNLSAFRREV 1070
>gi|154448892 exportin 7 isoform b [Homo sapiens]
Length = 1087
Score = 115 bits (288), Expect = 2e-25
Identities = 231/1182 (19%), Positives = 450/1182 (38%), Gaps = 169/1182 (14%)
Query: 12 IAQLENAAKVLMAPPSMVNNEQRQHAEHIFLSFRKSKSPFAVCKHILETSKVDYVLFQAA 71
+AQLEN K L + R AE + F S + C+ +LE Y AA
Sbjct: 8 LAQLENLCKQLY---ETTDTTTRLQAEKALVEFTNSPDCLSKCQLLLERGSSSYSQLLAA 64
Query: 72 TAIMEAVVREWILLEKGSIESLRTFLLTYVLQRPNLQKYVREQILLAVAVIVKRGSLDKS 131
T + + V R L +R ++L Y+ RP L +V + ++ A I K G D
Sbjct: 65 TCLTKLVSRTNNPLPLEQRIDIRNYVLNYLATRPKLATFVTQALIQLYARITKLGWFDCQ 124
Query: 132 IDCKSIFHEVSQLISSGNPTVQTLACSILTALLSEFSSSSKTSNIGLSMEFHGNCKRVFQ 191
D + ++ + +V+ C I +LS+ ++ ++ + H F+
Sbjct: 125 KDDYVFRNAITDVTRFLQDSVE--YCIIGVTILSQLTNEINQADTTHPLTKHRKIASSFR 182
Query: 192 EEDLRQIFMLTVEVLQEFSRRE-NLNAQ-MSSVFQRYLALANQVLSWNFLPPNLGRHYIA 249
+ L IF L+ +L++ S + NLN + + + L L + L+++F+ +
Sbjct: 183 DSSLFDIFTLSCNLLKQASGKNLNLNDESQHGLLMQLLKLTHNCLNFDFIGTSTD----- 237
Query: 250 MFESSQNV-LLKPTESWRETLLDSRVMELFFTVHRKIREDSDMAQDSLQCLAQLASLHGP 308
ESS ++ ++ SWR LDS ++LFF ++ I + L CL Q+AS+
Sbjct: 238 --ESSDDLCTVQIPTSWRSAFLDSSTLQLFFDLYHSI--PPSFSPLVLSCLVQIASVRRS 293
Query: 309 IFPDEGSQVDYLAHFIEGLLNTI-NGIEIEDSEAVGISSIISNLITVFPRNVLTAIPSEL 367
+F + + +L+H ++G+ + N + D P N
Sbjct: 294 LF-NNAERAKFLSHLVDGVKRILENPQSLSD-----------------PNN--------- 326
Query: 368 FSSFVNCLTHLTCSFGRSAALEEVLDKDDMVYMEAYDKL--LESWLTLVQDDKHFHKGFF 425
+ F L L ++ + L +V + +++ + A + L+ W + H+ +
Sbjct: 327 YHEFCRLLARLKSNY-QLGELVKVENYPEVIRLIANFTVTSLQHW-EFAPNSVHYLLSLW 384
Query: 426 TQHAVQV-FNSYIQCHLAAPDGTRNLTANGVASREEEEISELQEDDRDQFSD------QL 478
+ A V + + H+ T +T + SR E L++ D D QL
Sbjct: 385 QRLAASVPYVKATEPHM-LETYTPEVTKAYITSRLESVHIILRDGLEDPLEDTGLVQQQL 443
Query: 479 ASVGMLGRIAAEHCIPLLTSLLEERVTRLHGQLQRHQQQLLASPGSSTVDNKMLDDLYED 538
+ +GR E LL L + Q + Q+LL S +S +D + +
Sbjct: 444 DQLSTIGRCEYEKTCALLVQLFD--------QSAQSYQELLQSASASPMDIAVQEG---R 492
Query: 539 IHWLILVTGYLLADDTQGETPLIPPEIMEYSIKHSSEVDINTTLQILGSPGEKASSIPGY 598
+ WL+ + G ++ V +T + GE
Sbjct: 493 LTWLVYIIGAVI----------------------GGRVSFASTDEQDAMDGE-------- 522
Query: 599 NRTDSVIRLLSAILRVSEVESRAIRADLTHLLSPQMGKDIVWFLKRWAKTYLLVDEKLYD 658
L+ +L++ + + L M F K + + KLY
Sbjct: 523 --------LVCRVLQLMNLTDSRLAQAGNEKLELAMLSFFEQFRKIYIGDQVQKSSKLYR 574
Query: 659 QISLPFSTAFGADTEGSQWIIGYLLQKVISNLSVWSSEQDLANDTVQLLVTL------VE 712
++ S G + E ++ + K+I+NL W + + + T+QLL L V
Sbjct: 575 RL----SEVLGLNDE--TMVLSVFIGKIITNLKYWGRCEPITSKTLQLLNDLSIGYSSVR 628
Query: 713 RRERANLV-IQCENWWNLAKQFASRSPPLNFLSSPVQRTLMKALVLGGFAHMDTETKQQY 771
+ + + V N + F + N + T A LG +D +
Sbjct: 629 KLVKLSAVQFMLNNHTSEHFSFLGINNQSNLTDMRCRTTFYTA--LGRLLMVDLGEDEDQ 686
Query: 772 WTEVLQPLQQRFLRVINQENFQQMCQQEEVKQEITATLEALCGIAEATQI-DNVAILFNF 830
+ + + PL F + Q ++E K+ + + L GIA A + +LF +
Sbjct: 687 YEQFMLPLTAAF-EAVAQMFSTNSFNEQEAKRTLVGLVRDLRGIAFAFNAKTSFMMLFEW 745
Query: 831 LM-DFLTNCIGLMEVYKNTPETVNLIIEVFVEVAHKQICYL----GESKAMNLYEACLTL 885
+ ++ +E++ + P ++++ E+ H + L + L+ +
Sbjct: 746 IYPSYMPILQRAIELWYHDPACTTPVLKLMAELVHNRSQRLQFDVSSPNGILLFRETSKM 805
Query: 886 LQVYSKNNLGRQRIDVTAEEEQY----QDLLLIMELLTNLLSKEFIDFSDTDEVFRGHEP 941
+ +Y L + +++ Y + + + +L LS +++F VFR +
Sbjct: 806 ITMYGNRIL---TLGEVPKDQVYALKLKGISICFSMLKAALSGSYVNFG----VFRLYGD 858
Query: 942 GQAANRSVSAADVVLYGVNLILPLMSQDLLKFPTLCNQYYKLITFICEIFPEKIPQLPED 1001
N + + L+L + DLL +P L YY L+ + + I L
Sbjct: 859 DALDN-------ALQTFIKLLLSIPHSDLLDYPKLSQSYYSLLEVLTQDHMNFIASLEPH 911
Query: 1002 LFKSLMYSLELGMTSMSSEVCQLCLEAL----TPLAEQCAKA---------QETDSPLFL 1048
+ ++ S+ G+T++ + VC C L T L +Q +++ QE+D L +
Sbjct: 912 VIMYILSSISEGLTALDTMVCTGCCSCLDHIVTYLFKQLSRSTKKRTTPLNQESDRFLHI 971
Query: 1049 ATRH------FLKLVFDMLVLQKHNTEMTTAAGEAFYTLVCLHQAEYSELVETLLSSQQD 1102
+H L V ++++ + + + + L+ L++ +S+L ++++S Q
Sbjct: 972 MQQHPEMIQQMLSTVLNIIIFEDCRNQWSMS--RPLLGLILLNEKYFSDLRNSIVNS-QP 1028
Query: 1103 PVIYQRLADAFNKLTASSTPPTLDRKQKMAFLKSLEEFMANV 1144
P Q + F L L K + F ++L F V
Sbjct: 1029 PEKQQAMHLCFENL-MEGIERNLLTKNRDRFTQNLSAFRREV 1069
>gi|154448894 exportin 7 isoform a [Homo sapiens]
Length = 1096
Score = 112 bits (281), Expect = 2e-24
Identities = 233/1189 (19%), Positives = 453/1189 (38%), Gaps = 174/1189 (14%)
Query: 12 IAQLENAAKVLMAPPSMVNNEQRQHAEHIFLSFRKSKSPFAVCKHILETSKVDYVLFQAA 71
+AQLEN K L + R AE + F S + C+ +LE Y AA
Sbjct: 8 LAQLENLCKQLY---ETTDTTTRLQAEKALVEFTNSPDCLSKCQLLLERGSSSYSQLLAA 64
Query: 72 TAIMEAVVREWILLEKGSIESLRTFLLTYVLQRPNLQKYVREQILLAVAVIVKRGSLDKS 131
T + + V R L +R ++L Y+ RP L +V + ++ A I K G D
Sbjct: 65 TCLTKLVSRTNNPLPLEQRIDIRNYVLNYLATRPKLATFVTQALIQLYARITKLGWFDCQ 124
Query: 132 IDCKSIFHEVSQLISSGNPTVQ--TLACSILTALLSEFSSSSKT-----SNIGLSMEFHG 184
D + ++ + +V+ + +IL+ L +E + S T ++ + H
Sbjct: 125 KDDYVFRNAITDVTRFLQDSVEYCIIGVTILSQLTNEINQVSATAFLIEADTTHPLTKHR 184
Query: 185 NCKRVFQEEDLRQIFMLTVEVLQEFSRRE-NLNAQ-MSSVFQRYLALANQVLSWNFLPPN 242
F++ L IF L+ +L++ S + NLN + + + L L + L+++F+ +
Sbjct: 185 KIASSFRDSSLFDIFTLSCNLLKQASGKNLNLNDESQHGLLMQLLKLTHNCLNFDFIGTS 244
Query: 243 LGRHYIAMFESSQNV-LLKPTESWRETLLDSRVMELFFTVHRKIREDSDMAQDSLQCLAQ 301
ESS ++ ++ SWR LDS ++LFF ++ I + L CL Q
Sbjct: 245 TD-------ESSDDLCTVQIPTSWRSAFLDSSTLQLFFDLYHSI--PPSFSPLVLSCLVQ 295
Query: 302 LASLHGPIFPDEGSQVDYLAHFIEGLLNTI-NGIEIEDSEAVGISSIISNLITVFPRNVL 360
+AS+ +F + + +L+H ++G+ + N + D P N
Sbjct: 296 IASVRRSLF-NNAERAKFLSHLVDGVKRILENPQSLSD-----------------PNN-- 335
Query: 361 TAIPSELFSSFVNCLTHLTCSFGRSAALEEVLDKDDMVYMEAYDKL--LESWLTLVQDDK 418
+ F L L ++ + L +V + +++ + A + L+ W +
Sbjct: 336 -------YHEFCRLLARLKSNY-QLGELVKVENYPEVIRLIANFTVTSLQHW-EFAPNSV 386
Query: 419 HFHKGFFTQHAVQV-FNSYIQCHLAAPDGTRNLTANGVASREEEEISELQEDDRDQFSD- 476
H+ + + A V + + H+ T +T + SR E L++ D D
Sbjct: 387 HYLLSLWQRLAASVPYVKATEPHM-LETYTPEVTKAYITSRLESVHIILRDGLEDPLEDT 445
Query: 477 -----QLASVGMLGRIAAEHCIPLLTSLLEERVTRLHGQLQRHQQQLLASPGSSTVDNKM 531
QL + +GR E LL L + Q + Q+LL S +S +D +
Sbjct: 446 GLVQQQLDQLSTIGRCEYEKTCALLVQLFD--------QSAQSYQELLQSASASPMDIAV 497
Query: 532 LDDLYEDIHWLILVTGYLLADDTQGETPLIPPEIMEYSIKHSSEVDINTTLQILGSPGEK 591
+ + WL+ + G ++ V +T + GE
Sbjct: 498 QEG---RLTWLVYIIGAVI----------------------GGRVSFASTDEQDAMDGE- 531
Query: 592 ASSIPGYNRTDSVIRLLSAILRVSEVESRAIRADLTHLLSPQMGKDIVWFLKRWAKTYLL 651
L+ +L++ + + L M F K + +
Sbjct: 532 ---------------LVCRVLQLMNLTDSRLAQAGNEKLELAMLSFFEQFRKIYIGDQVQ 576
Query: 652 VDEKLYDQISLPFSTAFGADTEGSQWIIGYLLQKVISNLSVWSSEQDLANDTVQLLVTL- 710
KLY ++ S G + E ++ + K+I+NL W + + + T+QLL L
Sbjct: 577 KSSKLYRRL----SEVLGLNDE--TMVLSVFIGKIITNLKYWGRCEPITSKTLQLLNDLS 630
Query: 711 -----VERRERANLV-IQCENWWNLAKQFASRSPPLNFLSSPVQRTLMKALVLGGFAHMD 764
V + + + V N + F + N + T A LG +D
Sbjct: 631 IGYSSVRKLVKLSAVQFMLNNHTSEHFSFLGINNQSNLTDMRCRTTFYTA--LGRLLMVD 688
Query: 765 TETKQQYWTEVLQPLQQRFLRVINQENFQQMCQQEEVKQEITATLEALCGIAEATQI-DN 823
+ + + + PL F + Q ++E K+ + + L GIA A +
Sbjct: 689 LGEDEDQYEQFMLPLTAAF-EAVAQMFSTNSFNEQEAKRTLVGLVRDLRGIAFAFNAKTS 747
Query: 824 VAILFNFLM-DFLTNCIGLMEVYKNTPETVNLIIEVFVEVAHKQICYL----GESKAMNL 878
+LF ++ ++ +E++ + P ++++ E+ H + L + L
Sbjct: 748 FMMLFEWIYPSYMPILQRAIELWYHDPACTTPVLKLMAELVHNRSQRLQFDVSSPNGILL 807
Query: 879 YEACLTLLQVYSKNNLGRQRIDVTAEEEQY----QDLLLIMELLTNLLSKEFIDFSDTDE 934
+ ++ +Y L + +++ Y + + + +L LS +++F
Sbjct: 808 FRETSKMITMYGNRIL---TLGEVPKDQVYALKLKGISICFSMLKAALSGSYVNFG---- 860
Query: 935 VFRGHEPGQAANRSVSAADVVLYGVNLILPLMSQDLLKFPTLCNQYYKLITFICEIFPEK 994
VFR + N + + L+L + DLL +P L YY L+ + +
Sbjct: 861 VFRLYGDDALDN-------ALQTFIKLLLSIPHSDLLDYPKLSQSYYSLLEVLTQDHMNF 913
Query: 995 IPQLPEDLFKSLMYSLELGMTSMSSEVCQLCLEAL----TPLAEQCAKA---------QE 1041
I L + ++ S+ G+T++ + VC C L T L +Q +++ QE
Sbjct: 914 IASLEPHVIMYILSSISEGLTALDTMVCTGCCSCLDHIVTYLFKQLSRSTKKRTTPLNQE 973
Query: 1042 TDSPLFLATRH------FLKLVFDMLVLQKHNTEMTTAAGEAFYTLVCLHQAEYSELVET 1095
+D L + +H L V ++++ + + + + L+ L++ +S+L +
Sbjct: 974 SDRFLHIMQQHPEMIQQMLSTVLNIIIFEDCRNQWSMS--RPLLGLILLNEKYFSDLRNS 1031
Query: 1096 LLSSQQDPVIYQRLADAFNKLTASSTPPTLDRKQKMAFLKSLEEFMANV 1144
+++S Q P Q + F L L K + F ++L F V
Sbjct: 1032 IVNS-QPPEKQQAMHLCFENL-MEGIERNLLTKNRDRFTQNLSAFRREV 1078
>gi|12597633 RAN binding protein 17 [Homo sapiens]
Length = 1088
Score = 73.2 bits (178), Expect = 1e-12
Identities = 71/299 (23%), Positives = 136/299 (45%), Gaps = 18/299 (6%)
Query: 33 QRQHAEHIFLSFRKSKSPFAVCKHILETSKVDYVLFQAATAIMEAVVREWILLEKGSIES 92
QR AE L S + C+ +LE Y AAT + + V R L + ++
Sbjct: 26 QRIEAEKALLELIDSPECLSKCQLLLEQGTTSYAQLLAATCLSKLVSRVSPLPVEQRMD- 84
Query: 93 LRTFLLTYVLQRPNLQKYVREQILLAVAVIVKRGSLDKSIDCKSIFHE-VSQLISSGNPT 151
+R ++L YV +P L +V + ++ +A I K G + D + +F E ++ + T
Sbjct: 85 IRNYILNYVASQPKLAPFVIQALIQVIAKITKLGWFEVQKD-QFVFREIIADVKKFLQGT 143
Query: 152 VQTLACSILTALLSEFSSSSKTSNIGLSMEFHGNCKRVFQEEDLRQIFMLTVEVLQE-FS 210
V+ C I +LSE + + H F++ L+ + +L +L+E F+
Sbjct: 144 VE--HCIIGVIILSELTQEMNLVDYSRPSAKHRKIATSFRDTSLKDVLVLACSLLKEVFA 201
Query: 211 RRENLNAQ-MSSVFQRYLALANQVLSWNFLPPNLGRHYIAMFESSQNV-LLKPTESWRET 268
+ NL Q ++ + L L L+++F+ + ES+ ++ ++ +WR
Sbjct: 202 KPLNLQDQCQQNLVMQVLKLVLNCLNFDFIGSSAD-------ESADDLCTVQIPTTWRTI 254
Query: 269 LLDSRVMELFFTVHRKIREDSDMAQDSLQCLAQLASLHGPIFPDEGSQVDYLAHFIEGL 327
L+ ++LFF ++ + ++Q +L CL Q AS +F + + YL + I+G+
Sbjct: 255 FLEPETLDLFFNLYHSL--PPLLSQLALSCLVQFASTRRSLF-NSPERAKYLGNLIKGV 310
Score = 52.4 bits (124), Expect = 2e-06
Identities = 111/551 (20%), Positives = 210/551 (38%), Gaps = 66/551 (11%)
Query: 638 IVWFLKRWAKTYLLVDEKLYDQISLPFSTAFGADTEGSQWIIGYLLQKVISNLSVWSSEQ 697
I+WFL ++ KTY+ + ++ S G + ++ + K+++NL W +
Sbjct: 549 ILWFLDQFRKTYVGDQLQRTSKVYARMSEVLGITDDNH--VLETFMTKIVTNLKYWGRYE 606
Query: 698 DLANDTVQLLVTLVERRERANLVIQCENWWNLAKQFASRSPPL-----NFLSSPVQRTLM 752
+ + T+Q L L +++ + + K S P N S +
Sbjct: 607 PVISRTLQFLNDLSVGYILLKKLVKIDAVKFMLKNHTSEHFPFLGISDNHSLSDFRCRTT 666
Query: 753 KALVLGGFAHMDTETKQQYWTEVLQPLQQRFLRVINQENFQQMCQQEEVKQEITATLEAL 812
L +D + + + PL F V+ + F +QE+VK+ + L
Sbjct: 667 FYTALTRLLMVDLGEDEDEFENFMLPLTVAFETVL--QIFNNNFKQEDVKRMLIGLARDL 724
Query: 813 CGIAEATQID-NVAILFNFLMD-FLTNCIGLMEVYKNTPETVNLIIEVFVEVAHKQ---- 866
GIA A + +LF+++ +L +E + P I+++ E+ +
Sbjct: 725 RGIAFALNTKTSYTMLFDWMYPTYLPLLQNAVERWYGEPTCTTPILKLMAELMQNRSQRL 784
Query: 867 ---------ICYLGESKAMNLYEACLTLLQVYSKNNLGRQRIDVTAEEEQYQDLLLIMEL 917
I E+ M C Q+ S +L + +I + + + +
Sbjct: 785 NFDVSSPNGILLFREASKM----VCTYGNQILSLGSLSKDQI----YPMKLKGISICYSA 836
Query: 918 LTNLLSKEFIDFSDTDEVFRGHEPGQAANRSVSAADVVLYGVNLILPLMSQDLLKFPTLC 977
L + L ++ F VF+ + N V+ V ++L + DLL++ L
Sbjct: 837 LKSALCGNYVSFG----VFKLYGDNHFDN-------VLQAFVKMLLSVSHSDLLQYRKLS 885
Query: 978 NQYYKLITFICEIFPEKIPQLPEDLFKSLMYSLELGMTSMSSEVCQLCLEALTPLAEQCA 1037
YY L+ + + I L + ++ S+ G+T++ + V C +L +
Sbjct: 886 QSYYPLLECLTQDHMSFIINLEPPVLMYVLTSISEGLTTLDTVVSSSCCTSLDYIVTYLF 945
Query: 1038 K--AQETDSPLFL--ATR------HFLKLVFDMLVLQKHNTEMTT----------AAGEA 1077
K A+E PL AT+ HF++ D+L Q + M T +
Sbjct: 946 KHIAKEGKKPLRCREATQAGQRLLHFMQQNPDVL-QQMMSVLMNTIVFEDCRNQWSVSRP 1004
Query: 1078 FYTLVCLHQAEYSELVETLLSSQQDPVIYQRLADAFNKLTASSTPPTLDRKQKMAFLKSL 1137
L+ L++ +SEL +L++SQ P + LA F L L K + F ++L
Sbjct: 1005 LLGLILLNEKYFSELRASLINSQPLPK-QEVLAQCFRNL-MEGVEQNLSVKNRDRFTQNL 1062
Query: 1138 EEFMANVGGLL 1148
F +V L
Sbjct: 1063 SVFRRDVAEAL 1073
>gi|21071052 helicase-like transcription factor [Homo sapiens]
Length = 1009
Score = 37.0 bits (84), Expect = 0.11
Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Query: 970 LLKFPTLCNQYYKLITFICEIFPEKIPQLPEDLFKSLMYSLELGMTSMSSEVCQLCLEAL 1029
LL+ +C Y L + P PE+L K L+ ++L ++S S E C +CL++L
Sbjct: 709 LLRLRQICCHTYLLTNAVSSNGPSG-NDTPEELRKKLIRKMKLILSSGSDEECAICLDSL 767
Query: 1030 T-PLAEQCA 1037
T P+ CA
Sbjct: 768 TVPVITHCA 776
>gi|21071054 helicase-like transcription factor [Homo sapiens]
Length = 1009
Score = 37.0 bits (84), Expect = 0.11
Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Query: 970 LLKFPTLCNQYYKLITFICEIFPEKIPQLPEDLFKSLMYSLELGMTSMSSEVCQLCLEAL 1029
LL+ +C Y L + P PE+L K L+ ++L ++S S E C +CL++L
Sbjct: 709 LLRLRQICCHTYLLTNAVSSNGPSG-NDTPEELRKKLIRKMKLILSSGSDEECAICLDSL 767
Query: 1030 T-PLAEQCA 1037
T P+ CA
Sbjct: 768 TVPVITHCA 776
>gi|82659109 retinoblastoma-associated factor 600 [Homo sapiens]
Length = 5183
Score = 37.0 bits (84), Expect = 0.11
Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 5/83 (6%)
Query: 190 FQEEDLRQIFMLTVEVLQEFSRRENLNAQMSSVFQRYLALANQVLSWNFLPPNLGRHYIA 249
F E R I L V+++QE S N++AQM V L LA +L +++L + +
Sbjct: 821 FTETGRRAILSLFVQIIQELS--VNMDAQMRFV---PLILARLLLIFDYLLHQYSKAPVY 875
Query: 250 MFESSQNVLLKPTESWRETLLDS 272
+FE Q+ LL P W DS
Sbjct: 876 LFEQVQHNLLSPPFGWASGSQDS 898
>gi|126032350 protein kinase, DNA-activated, catalytic polypeptide
isoform 2 [Homo sapiens]
Length = 4097
Score = 36.2 bits (82), Expect = 0.18
Identities = 44/179 (24%), Positives = 78/179 (43%), Gaps = 25/179 (13%)
Query: 975 TLCNQYYKLITFICEIFPEKIPQLPEDLFKSLMYSLELGMTSMSSE----VCQLCLEALT 1030
T+ + Y+L+ + E+ P ++ E+LF++ + L+ MTS E V CL+ L+
Sbjct: 169 TVLEKVYELLGLLGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLS 228
Query: 1031 PLAEQCAKAQETDSPLFLATRHF-LKLVFDMLVLQKHNTEMTTAAGEAFYTLVCLHQAEY 1089
L K+ E D +F LK + + L+++ A A L LH +++
Sbjct: 229 SLLCNFTKSMEEDPQTSREIFNFVLKAIRPQIDLKRY------AVPSAGLRLFALHASQF 282
Query: 1090 SELVETLLSSQQDPVIYQRLADAFNKLTASSTPPTLDRKQKMAFLKSLEEFMANVGGLL 1148
S LL + Y L + K A + + + K A L +LE F+ V ++
Sbjct: 283 S---TCLLDN------YVSLFEVLLKWCAHT-----NVELKKAALSALESFLKQVSNMV 327
>gi|13654237 protein kinase, DNA-activated, catalytic polypeptide
isoform 1 [Homo sapiens]
Length = 4128
Score = 36.2 bits (82), Expect = 0.18
Identities = 44/179 (24%), Positives = 78/179 (43%), Gaps = 25/179 (13%)
Query: 975 TLCNQYYKLITFICEIFPEKIPQLPEDLFKSLMYSLELGMTSMSSE----VCQLCLEALT 1030
T+ + Y+L+ + E+ P ++ E+LF++ + L+ MTS E V CL+ L+
Sbjct: 169 TVLEKVYELLGLLGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLS 228
Query: 1031 PLAEQCAKAQETDSPLFLATRHF-LKLVFDMLVLQKHNTEMTTAAGEAFYTLVCLHQAEY 1089
L K+ E D +F LK + + L+++ A A L LH +++
Sbjct: 229 SLLCNFTKSMEEDPQTSREIFNFVLKAIRPQIDLKRY------AVPSAGLRLFALHASQF 282
Query: 1090 SELVETLLSSQQDPVIYQRLADAFNKLTASSTPPTLDRKQKMAFLKSLEEFMANVGGLL 1148
S LL + Y L + K A + + + K A L +LE F+ V ++
Sbjct: 283 S---TCLLDN------YVSLFEVLLKWCAHT-----NVELKKAALSALESFLKQVSNMV 327
>gi|113430845 PREDICTED: similar to protein kinase, DNA-activated,
catalytic polypeptide [Homo sapiens]
Length = 4096
Score = 36.2 bits (82), Expect = 0.18
Identities = 44/179 (24%), Positives = 78/179 (43%), Gaps = 25/179 (13%)
Query: 975 TLCNQYYKLITFICEIFPEKIPQLPEDLFKSLMYSLELGMTSMSSE----VCQLCLEALT 1030
T+ + Y+L+ + E+ P ++ E+LF++ + L+ MTS E V CL+ L+
Sbjct: 169 TVLEKVYELLGLLGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLS 228
Query: 1031 PLAEQCAKAQETDSPLFLATRHF-LKLVFDMLVLQKHNTEMTTAAGEAFYTLVCLHQAEY 1089
L K+ E D +F LK + + L+++ A A L LH +++
Sbjct: 229 SLLCNFTKSMEEDPQTSREIFNFVLKAIRPQIDLKRY------AVPSAGLRLFALHASQF 282
Query: 1090 SELVETLLSSQQDPVIYQRLADAFNKLTASSTPPTLDRKQKMAFLKSLEEFMANVGGLL 1148
S LL + Y L + K A + + + K A L +LE F+ V ++
Sbjct: 283 S---TCLLDN------YVSLFEVLLKWCAHT-----NVELKKAALSALESFLKQVSNMV 327
>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
[Homo sapiens]
Length = 6907
Score = 36.2 bits (82), Expect = 0.18
Identities = 62/286 (21%), Positives = 116/286 (40%), Gaps = 48/286 (16%)
Query: 740 LNFLSSPVQRTLMKALVLGGFAHMDTETKQQYWTEVLQPLQQRFLRVINQENFQQMCQQE 799
LN L S VQ D Q++ ++ P QQ +QQ+ Q+
Sbjct: 3734 LNELDSEVQ----------DIVEQDPGQAQEWMDNLMIPFQQ----------YQQVSQRA 3773
Query: 800 EVK----QEITATLEALCGIAEATQ--IDNVAIL------FNFLMDFLTNCIGLMEVYKN 847
E + + T +E + ++T+ I+N + L ++ L + + ++
Sbjct: 3774 ECRTSQLNKATVKMEEYSDLLKSTEAWIENTSHLLANPADYDSLRTLSHHASTVQMALED 3833
Query: 848 TPETVNLIIEVFVEVAHKQICYLGESKAMNLYEAC--LTLLQ---VYSKNNLGRQRIDVT 902
+ + NL+ +F+++ I + + ++ E +T LQ + S + R DV
Sbjct: 3834 SEQKHNLLHSIFMDLEDLSIIFETDELTQSIQELSNQVTALQQKIMESLPQIQRMADDVV 3893
Query: 903 AEEEQYQDL-LLIMELLTNLLSKEFIDFSDTDEVFRGH---EPGQAANRSVSAADVVLYG 958
A E + + + + ++ T LLSKE DFS + + G E + +++ A++V Y
Sbjct: 3894 AIESEVKSMEKRVSKIKTILLSKEIFDFSPEEHLKHGEVILENIRPMKKTI--AEIVSYQ 3951
Query: 959 VNLILPLMSQDLLKFPTLCNQYYKLITFICEIFPEKIPQLPEDLFK 1004
V L LP L NQ + I + E + Q +L K
Sbjct: 3952 VELRLPQTGMKPLPVFQRTNQLLQDIKLL-----ENVTQEQNELLK 3992
>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
[Homo sapiens]
Length = 6885
Score = 36.2 bits (82), Expect = 0.18
Identities = 62/286 (21%), Positives = 116/286 (40%), Gaps = 48/286 (16%)
Query: 740 LNFLSSPVQRTLMKALVLGGFAHMDTETKQQYWTEVLQPLQQRFLRVINQENFQQMCQQE 799
LN L S VQ D Q++ ++ P QQ +QQ+ Q+
Sbjct: 3734 LNELDSEVQ----------DIVEQDPGQAQEWMDNLMIPFQQ----------YQQVSQRA 3773
Query: 800 EVK----QEITATLEALCGIAEATQ--IDNVAIL------FNFLMDFLTNCIGLMEVYKN 847
E + + T +E + ++T+ I+N + L ++ L + + ++
Sbjct: 3774 ECRTSQLNKATVKMEEYSDLLKSTEAWIENTSHLLANPADYDSLRTLSHHASTVQMALED 3833
Query: 848 TPETVNLIIEVFVEVAHKQICYLGESKAMNLYEAC--LTLLQ---VYSKNNLGRQRIDVT 902
+ + NL+ +F+++ I + + ++ E +T LQ + S + R DV
Sbjct: 3834 SEQKHNLLHSIFMDLEDLSIIFETDELTQSIQELSNQVTALQQKIMESLPQIQRMADDVV 3893
Query: 903 AEEEQYQDL-LLIMELLTNLLSKEFIDFSDTDEVFRGH---EPGQAANRSVSAADVVLYG 958
A E + + + + ++ T LLSKE DFS + + G E + +++ A++V Y
Sbjct: 3894 AIESEVKSMEKRVSKIKTILLSKEIFDFSPEEHLKHGEVILENIRPMKKTI--AEIVSYQ 3951
Query: 959 VNLILPLMSQDLLKFPTLCNQYYKLITFICEIFPEKIPQLPEDLFK 1004
V L LP L NQ + I + E + Q +L K
Sbjct: 3952 VELRLPQTGMKPLPVFQRTNQLLQDIKLL-----ENVTQEQNELLK 3992
>gi|46049063 exportin 6 [Homo sapiens]
Length = 1125
Score = 36.2 bits (82), Expect = 0.18
Identities = 26/118 (22%), Positives = 52/118 (44%), Gaps = 4/118 (3%)
Query: 31 NEQRQHAEHIFLSFRKSKSPFAVCKHILETSKVDYVLFQAATAIMEAVVREWILLEKGSI 90
NE+++ E + +F + + C + L +++ DYV+ + T + + W+ +
Sbjct: 25 NERKREIEELLNNFAQQIGAWRFCLYFLSSTRNDYVMMYSLTVFENLINKMWLGVPSQDK 84
Query: 91 ESLRTFLLTYVL-QRPNLQKYVREQILLAVAVIVKRGSLDKSIDCKSIFHEVSQLISS 147
+R+ L +L L ++R ++ VIV G D + F + QLI S
Sbjct: 85 MEIRSCLPKLLLAHHKTLPYFIRNKL---CKVIVDIGRQDWPMFYHDFFTNILQLIQS 139
>gi|224831257 importin 13 [Homo sapiens]
Length = 963
Score = 33.1 bits (74), Expect = 1.6
Identities = 44/227 (19%), Positives = 89/227 (39%), Gaps = 5/227 (2%)
Query: 3 AAALGPPEVIAQLENAAKVLMAPPSMVNNEQRQHAEHIFLSFRKSKSPFAVCKHILETSK 62
A A P + +EN K L N E + A+ + + S + +L+ K
Sbjct: 11 AGAGAAPALDFTVENVEKALHQLYYDPNIENKNLAQKWLMQAQVSPQAWHFSWQLLQPDK 70
Query: 63 VDYVLFQAATAIMEAVVREWILLEKGSIESLRTFLLTYVLQRPNLQKYVREQILLAVAVI 122
V + + A+A+ + R W + ESL+ L T + + + K V ++ +A+A +
Sbjct: 71 VPEIQYFGASALHIKISRYWSDIPTDQYESLKAQLFTQITRFASGSKIVLTRLCVALASL 130
Query: 123 VKRGSLDKSIDCKSIFHEVSQLISSGNPTVQTLACSILTALLSEFSSSSKTSNIGLSMEF 182
+ + C ++ V + +P C L LL+ +TS + ++
Sbjct: 131 A-LSMMPDAWPC-AVADMVRLFQAEDSPVDGQGRCLALLELLTVLPEEFQTSRL---PQY 185
Query: 183 HGNCKRVFQEEDLRQIFMLTVEVLQEFSRRENLNAQMSSVFQRYLAL 229
R + +F L ++LQ+ S + ++ F ++ L
Sbjct: 186 RKGLVRTSLAVECGAVFPLLEQLLQQPSSPSCVRQKVLKCFSSWVQL 232
>gi|145309324 FH2 domain containing 1 [Homo sapiens]
Length = 1143
Score = 31.6 bits (70), Expect = 4.5
Identities = 33/145 (22%), Positives = 58/145 (40%), Gaps = 22/145 (15%)
Query: 370 SFVNCLTHLTCSFGRSAALEEVLDKDDMVYMEAYDKL---------LESWLTLVQDDKHF 420
S N L F R+ +L+E + +D + + D L LE W +QD+ +
Sbjct: 369 SLENTEAELHLLFVRTKSLKENIQRDGELCQQMEDFLQFAIEKLRELECWKQELQDEAYT 428
Query: 421 HKGFFTQ--------HAVQVFNSYIQCHLAAPDGTRNLTANGVASREEEEISELQEDDRD 472
FF + Q+F + A + A +E ++ L+E ++
Sbjct: 429 LIDFFCEDKKTMKLDECFQIFRDFCTKFNKAVKDNHDREA-----QELRQLQRLKEQEQK 483
Query: 473 QFSDQLASVGMLGRIAAEHCIPLLT 497
Q S +G GR ++E+ + LLT
Sbjct: 484 QRSWATGELGAFGRSSSENDVELLT 508
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,782,930
Number of Sequences: 37866
Number of extensions: 1608451
Number of successful extensions: 4803
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 4752
Number of HSP's gapped (non-prelim): 45
length of query: 1151
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1038
effective length of database: 13,968,660
effective search space: 14499469080
effective search space used: 14499469080
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.