Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 148806902
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148806902 TBC1 domain family, member 12 [Homo sapiens]
(775 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148806902 TBC1 domain family, member 12 [Homo sapiens] 1573 0.0
gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens] 663 0.0
gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens] 663 0.0
gi|164565381 TBC1 domain family, member 14 isoform b [Homo sapiens] 618 e-177
gi|68299759 ecotropic viral integration site 5 [Homo sapiens] 122 1e-27
gi|229577000 ecotropic viral integration site 5-like isoform 1 [... 111 2e-24
gi|21687020 ecotropic viral integration site 5-like isoform 2 [H... 111 2e-24
gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens] 110 4e-24
gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens] 110 4e-24
gi|164519084 RAB GTPase activating protein 1 [Homo sapiens] 108 1e-23
gi|78217386 RAB GTPase activating protein 1-like isoform A [Homo... 100 4e-21
gi|13994322 TBC1 domain family, member 10A [Homo sapiens] 96 1e-19
gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member... 96 1e-19
gi|114688046 TBC1 domain family, member 4 [Homo sapiens] 92 2e-18
gi|38348348 TBC1 domain family, member 10C [Homo sapiens] 89 1e-17
gi|167614488 TBC1 domain family, member 10B [Homo sapiens] 88 3e-17
gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens] 81 3e-15
gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens] 81 3e-15
gi|38570101 TBC1 domain family, member 8B (with GRAM domain) iso... 77 6e-14
gi|29648315 small G protein signaling modulator 3 [Homo sapiens] 76 1e-13
gi|90577185 TBC1 domain family member 3C [Homo sapiens] 73 9e-13
gi|149999613 TBC1 domain family, member 3B [Homo sapiens] 72 3e-12
gi|226693407 TBC1 domain family, member 3H [Homo sapiens] 71 3e-12
gi|14149985 TBC1 domain family, member 3F [Homo sapiens] 71 3e-12
gi|157502205 TBC1 domain family, member 3G [Homo sapiens] 71 3e-12
gi|183583565 TBC1 domain family, member 3 [Homo sapiens] 71 4e-12
gi|183583567 TBC1 domain family, member 3E [Homo sapiens] 71 4e-12
gi|183583563 TBC1 domain family, member 3D [Homo sapiens] 71 4e-12
gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Ho... 69 1e-11
gi|222352143 TBC1 domain family, member 2 [Homo sapiens] 68 4e-11
>gi|148806902 TBC1 domain family, member 12 [Homo sapiens]
Length = 775
Score = 1573 bits (4074), Expect = 0.0
Identities = 775/775 (100%), Positives = 775/775 (100%)
Query: 1 MVGPEDAGACSGRNPKLLPVPAPDPVGQDRKVIRATGGFGGGVGAVEPPEEADEEEEADE 60
MVGPEDAGACSGRNPKLLPVPAPDPVGQDRKVIRATGGFGGGVGAVEPPEEADEEEEADE
Sbjct: 1 MVGPEDAGACSGRNPKLLPVPAPDPVGQDRKVIRATGGFGGGVGAVEPPEEADEEEEADE 60
Query: 61 EEETPPRQLLQRYLAAAGEQLEPGLCYCPLPAGQAGAPPPSAAPRSDACLLGSGSKHRGA 120
EEETPPRQLLQRYLAAAGEQLEPGLCYCPLPAGQAGAPPPSAAPRSDACLLGSGSKHRGA
Sbjct: 61 EEETPPRQLLQRYLAAAGEQLEPGLCYCPLPAGQAGAPPPSAAPRSDACLLGSGSKHRGA 120
Query: 121 EVADGRAPRHEGMTNGDSGFLPGRDCRDLEEARGLARAGGRESRRRRPYGRLRLEGPGDE 180
EVADGRAPRHEGMTNGDSGFLPGRDCRDLEEARGLARAGGRESRRRRPYGRLRLEGPGDE
Sbjct: 121 EVADGRAPRHEGMTNGDSGFLPGRDCRDLEEARGLARAGGRESRRRRPYGRLRLEGPGDE 180
Query: 181 DADGAGSPSDWASPLEDPLRSCCLVAADAQEPEGAGSDSGDSPASSCSSSEDSEQRGVGA 240
DADGAGSPSDWASPLEDPLRSCCLVAADAQEPEGAGSDSGDSPASSCSSSEDSEQRGVGA
Sbjct: 181 DADGAGSPSDWASPLEDPLRSCCLVAADAQEPEGAGSDSGDSPASSCSSSEDSEQRGVGA 240
Query: 241 GGPEEGAPPATSAERTNGGAEPRLGFSDIHFNSRNTFQVSRGQSARDHLPPAGPPVPLPA 300
GGPEEGAPPATSAERTNGGAEPRLGFSDIHFNSRNTFQVSRGQSARDHLPPAGPPVPLPA
Sbjct: 241 GGPEEGAPPATSAERTNGGAEPRLGFSDIHFNSRNTFQVSRGQSARDHLPPAGPPVPLPA 300
Query: 301 AEQGPAGASARARRSGGFADFFTRNLFPKRTKELKSVVHSAPGWKLFGKVPPRENLQKTS 360
AEQGPAGASARARRSGGFADFFTRNLFPKRTKELKSVVHSAPGWKLFGKVPPRENLQKTS
Sbjct: 301 AEQGPAGASARARRSGGFADFFTRNLFPKRTKELKSVVHSAPGWKLFGKVPPRENLQKTS 360
Query: 361 KIIQQEYEARTGRTCKPPPQSSRRKNFEFEPLSTTALILEDRPSNLPAKSVEEALRHRQE 420
KIIQQEYEARTGRTCKPPPQSSRRKNFEFEPLSTTALILEDRPSNLPAKSVEEALRHRQE
Sbjct: 361 KIIQQEYEARTGRTCKPPPQSSRRKNFEFEPLSTTALILEDRPSNLPAKSVEEALRHRQE 420
Query: 421 YDEMVAEAKKREIKEAHKRKRIMKERFKQEENIASAMVIWINEILPNWEVMRSTRRVREL 480
YDEMVAEAKKREIKEAHKRKRIMKERFKQEENIASAMVIWINEILPNWEVMRSTRRVREL
Sbjct: 421 YDEMVAEAKKREIKEAHKRKRIMKERFKQEENIASAMVIWINEILPNWEVMRSTRRVREL 480
Query: 481 WWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRAKERWKSFSETSSENDTEGVSVADR 540
WWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRAKERWKSFSETSSENDTEGVSVADR
Sbjct: 481 WWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRAKERWKSFSETSSENDTEGVSVADR 540
Query: 541 EASLELIKLDISRTFPSLYIFQKGGPYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLIL 600
EASLELIKLDISRTFPSLYIFQKGGPYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLIL
Sbjct: 541 EASLELIKLDISRTFPSLYIFQKGGPYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLIL 600
Query: 601 NLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLHFKSYSLTP 660
NLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLHFKSYSLTP
Sbjct: 601 NLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLHFKSYSLTP 660
Query: 661 DIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYEDILLQMDFIHIA 720
DIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYEDILLQMDFIHIA
Sbjct: 661 DIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYEDILLQMDFIHIA 720
Query: 721 QFLTKLPEDITSEKLFSCIAAIQMQNSTKKWTQVFASVMKDIKEGDKNSSPALKS 775
QFLTKLPEDITSEKLFSCIAAIQMQNSTKKWTQVFASVMKDIKEGDKNSSPALKS
Sbjct: 721 QFLTKLPEDITSEKLFSCIAAIQMQNSTKKWTQVFASVMKDIKEGDKNSSPALKS 775
>gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens]
Length = 693
Score = 663 bits (1710), Expect = 0.0
Identities = 325/462 (70%), Positives = 387/462 (83%), Gaps = 5/462 (1%)
Query: 316 GGFADFFTRNLFPKRTKELKSVVHSAPGWKLFGKVPPRENLQKTSKIIQQEYEARTGRTC 375
G F++FF RNL ++ + + H+ GWKLFGK P REN QK SK IQ+EYE + GR
Sbjct: 233 GPFSNFFARNLLARK-QSARLDKHNDLGWKLFGKAPLRENAQKDSKRIQKEYEDKAGRPS 291
Query: 376 KPP-PQSSRRKNFEFEPLSTTALILEDRPSNLPAKSVEEALRHRQEYDEMVAEAKKREIK 434
KPP P+ + RKN +FEPLSTTALILEDRP+NLPAK EEA +HRQ+Y+EMV +AKKRE+K
Sbjct: 292 KPPSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELK 351
Query: 435 EAHKRKRIMKERFKQEENIASAMVIWINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVW 494
EA +RK+ ++ER + EE+I +A++ W NEILPNWE M +R+VR+LWWQG+PPSVRGKVW
Sbjct: 352 EAQRRKKQLEERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQGIPPSVRGKVW 411
Query: 495 SLAVGNELNITPELYEIFLSRAKERWKSFSETSSE--NDTEGVSVADREASLELIKLDIS 552
SLA+GNELNIT EL++I L+RAKERW+S S SE N+ G S ADREASLELIKLDIS
Sbjct: 412 SLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDIS 471
Query: 553 RTFPSLYIFQKGGPYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFA 612
RTFP+L IFQ+GGPYHD+LHSILGAYTCYRPDVGYVQGMSFIAAVLILNL+ ADAFIAF+
Sbjct: 472 RTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFS 531
Query: 613 NLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLY 672
NLLNKPCQ+AFFRVDH +ML YFA FEVFFEENL KLF HFK +LTPDIYLIDWIFTLY
Sbjct: 532 NLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLY 591
Query: 673 SKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYEDILLQMDFIHIAQFLTKLPEDITS 732
SKSLPLDLACR+WDVFCRDGEEFLFRT LGIL+L+EDIL +MDFIH+AQFLT+LPED+ +
Sbjct: 592 SKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQFLTRLPEDLPA 651
Query: 733 EKLFSCIAAIQMQNSTKKWTQVFASVMKDIKEGDKNSSPALK 774
E+LF+ IA IQMQ+ KKW QV ++ KD +E +K SP+L+
Sbjct: 652 EELFASIATIQMQSRNKKWAQVLTALQKDSREMEK-GSPSLR 692
>gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens]
Length = 693
Score = 663 bits (1710), Expect = 0.0
Identities = 325/462 (70%), Positives = 387/462 (83%), Gaps = 5/462 (1%)
Query: 316 GGFADFFTRNLFPKRTKELKSVVHSAPGWKLFGKVPPRENLQKTSKIIQQEYEARTGRTC 375
G F++FF RNL ++ + + H+ GWKLFGK P REN QK SK IQ+EYE + GR
Sbjct: 233 GPFSNFFARNLLARK-QSARLDKHNDLGWKLFGKAPLRENAQKDSKRIQKEYEDKAGRPS 291
Query: 376 KPP-PQSSRRKNFEFEPLSTTALILEDRPSNLPAKSVEEALRHRQEYDEMVAEAKKREIK 434
KPP P+ + RKN +FEPLSTTALILEDRP+NLPAK EEA +HRQ+Y+EMV +AKKRE+K
Sbjct: 292 KPPSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVVQAKKRELK 351
Query: 435 EAHKRKRIMKERFKQEENIASAMVIWINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVW 494
EA +RK+ ++ER + EE+I +A++ W NEILPNWE M +R+VR+LWWQG+PPSVRGKVW
Sbjct: 352 EAQRRKKQLEERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQGIPPSVRGKVW 411
Query: 495 SLAVGNELNITPELYEIFLSRAKERWKSFSETSSE--NDTEGVSVADREASLELIKLDIS 552
SLA+GNELNIT EL++I L+RAKERW+S S SE N+ G S ADREASLELIKLDIS
Sbjct: 412 SLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREASLELIKLDIS 471
Query: 553 RTFPSLYIFQKGGPYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFA 612
RTFP+L IFQ+GGPYHD+LHSILGAYTCYRPDVGYVQGMSFIAAVLILNL+ ADAFIAF+
Sbjct: 472 RTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLDTADAFIAFS 531
Query: 613 NLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLY 672
NLLNKPCQ+AFFRVDH +ML YFA FEVFFEENL KLF HFK +LTPDIYLIDWIFTLY
Sbjct: 532 NLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYLIDWIFTLY 591
Query: 673 SKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYEDILLQMDFIHIAQFLTKLPEDITS 732
SKSLPLDLACR+WDVFCRDGEEFLFRT LGIL+L+EDIL +MDFIH+AQFLT+LPED+ +
Sbjct: 592 SKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQFLTRLPEDLPA 651
Query: 733 EKLFSCIAAIQMQNSTKKWTQVFASVMKDIKEGDKNSSPALK 774
E+LF+ IA IQMQ+ KKW QV ++ KD +E +K SP+L+
Sbjct: 652 EELFASIATIQMQSRNKKWAQVLTALQKDSREMEK-GSPSLR 692
>gi|164565381 TBC1 domain family, member 14 isoform b [Homo sapiens]
Length = 413
Score = 618 bits (1594), Expect = e-177
Identities = 300/412 (72%), Positives = 354/412 (85%), Gaps = 4/412 (0%)
Query: 366 EYEARTGRTCKPP-PQSSRRKNFEFEPLSTTALILEDRPSNLPAKSVEEALRHRQEYDEM 424
EYE + GR KPP P+ + RKN +FEPLSTTALILEDRP+NLPAK EEA +HRQ+Y+EM
Sbjct: 2 EYEDKAGRPSKPPSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEM 61
Query: 425 VAEAKKREIKEAHKRKRIMKERFKQEENIASAMVIWINEILPNWEVMRSTRRVRELWWQG 484
V +AKKRE+KEA +RK+ ++ER + EE+I +A++ W NEILPNWE M +R+VR+LWWQG
Sbjct: 62 VVQAKKRELKEAQRRKKQLEERCRVEESIGNAVLTWNNEILPNWETMWCSRKVRDLWWQG 121
Query: 485 LPPSVRGKVWSLAVGNELNITPELYEIFLSRAKERWKSFSETSSE--NDTEGVSVADREA 542
+PPSVRGKVWSLA+GNELNIT EL++I L+RAKERW+S S SE N+ G S ADREA
Sbjct: 122 IPPSVRGKVWSLAIGNELNITHELFDICLARAKERWRSLSTGGSEVENEDAGFSAADREA 181
Query: 543 SLELIKLDISRTFPSLYIFQKGGPYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLILNL 602
SLELIKLDISRTFP+L IFQ+GGPYHD+LHSILGAYTCYRPDVGYVQGMSFIAAVLILNL
Sbjct: 182 SLELIKLDISRTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQGMSFIAAVLILNL 241
Query: 603 EEADAFIAFANLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLHFKSYSLTPDI 662
+ ADAFIAF+NLLNKPCQ+AFFRVDH +ML YFA FEVFFEENL KLF HFK +LTPDI
Sbjct: 242 DTADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDI 301
Query: 663 YLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYEDILLQMDFIHIAQF 722
YLIDWIFTLYSKSLPLDLACR+WDVFCRDGEEFLFRT LGIL+L+EDIL +MDFIH+AQF
Sbjct: 302 YLIDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQF 361
Query: 723 LTKLPEDITSEKLFSCIAAIQMQNSTKKWTQVFASVMKDIKEGDKNSSPALK 774
LT+LPED+ +E+LF+ IA IQMQ+ KKW QV ++ KD +E +K SP+L+
Sbjct: 362 LTRLPEDLPAEELFASIATIQMQSRNKKWAQVLTALQKDSREMEK-GSPSLR 412
>gi|68299759 ecotropic viral integration site 5 [Homo sapiens]
Length = 810
Score = 122 bits (306), Expect = 1e-27
Identities = 100/386 (25%), Positives = 171/386 (44%), Gaps = 44/386 (11%)
Query: 379 PQSSRRKNFEFEPLSTTALILEDRPSNLPAKSVEEALRHRQEYDEMVAEAKKREIKEAHK 438
P +S LST AL PS L +E L + E + E + ++ +
Sbjct: 52 PSTSLHTTSSSTTLSTPALS-PSSPSQLSPDDLE--LLAKLEEQNRLLETDSKSLRSVNG 108
Query: 439 RKRIMKERFKQEENIASAM--------VIWINEILPNWEVMRSTR--RVRELWWQGLPPS 488
+R + +S + ++W I+ WE +R + +V+EL +G+P
Sbjct: 109 SRRNSGSSLVSSSSASSNLSHLEEDSWILW-GRIVNEWEDVRKKKEKQVKELVHKGIPHH 167
Query: 489 VRGKVWSLAVGNELNITPELYEIFLSRAKERWKSFSETSSENDTEGVSVADREASLELIK 548
R VW L + + Y L K LI+
Sbjct: 168 FRAIVWQLLCSAQSMPIKDQYSELLKMTSPCEK------------------------LIR 203
Query: 549 LDISRTFPSLYIF-QKGGPYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLEEADA 607
DI+RT+P F +K +VL +++ AY+ +VGY QG +FI +L++ + E +A
Sbjct: 204 RDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEA 263
Query: 608 FIAFANLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDW 667
F F L+ F+ + + FE +E+L +LF+HF+S S +Y W
Sbjct: 264 FCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQEHLPELFVHFQSQSFHTSMYASSW 323
Query: 668 IFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYEDILLQMDFIHIAQFLTK-L 726
T++ + PL +A R++D+F +G E +FR GL +L++ + L+Q+D + Q K +
Sbjct: 324 FLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQMNQAELMQLDMEGMLQHFQKVI 383
Query: 727 PE--DITSEKLFSCIAAIQMQNSTKK 750
P D +KL AA Q++ ++KK
Sbjct: 384 PHQFDGVPDKLIQ--AAYQVKYNSKK 407
>gi|229577000 ecotropic viral integration site 5-like isoform 1
[Homo sapiens]
Length = 805
Score = 111 bits (278), Expect = 2e-24
Identities = 95/387 (24%), Positives = 165/387 (42%), Gaps = 45/387 (11%)
Query: 368 EARTGRTCKPPPQSSRRKNFEFEPLSTTALILEDRPSNLPAKSVEEALRHRQEYDEMVAE 427
EA + TC P S E E L+ L ++R +KS+ R+ +
Sbjct: 14 EALSAPTCSPTSDSENLSPDELELLAK--LEEQNRLLEADSKSMRSMNGSRRNSGSSLVS 71
Query: 428 AKKREIKEAHKRKRIMKERFKQEENIASAMVIWINEILPNWEVMRSTRR--VRELWWQGL 485
+ +H + ++W I WE R + ++EL +G+
Sbjct: 72 SSSASSNLSHLEE--------------DTWILW-GRIANEWEEWRRRKEKLLKELIRKGI 116
Query: 486 PPSVRGKVWSLAVGNELNITPELYEIFLSRAKERWKSFSETSSENDTEGVSVADREASLE 545
P R VW L L K ++ + SS + +
Sbjct: 117 PHHFRAIVWQL-----------LCSATDMPVKNQYSELLKMSSPCE-------------K 152
Query: 546 LIKLDISRTFPSLYIFQ-KGGPYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLEE 604
LI+ DI+RT+P F+ + +VL +++ AY+ +VGY QG +FI +L++ + E
Sbjct: 153 LIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPE 212
Query: 605 ADAFIAFANLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLHFKSYSLTPDIYL 664
+AF F L+ + F+ + + FE +E L L HF+S S +Y
Sbjct: 213 EEAFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFRSQSFHTSMYA 272
Query: 665 IDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYEDILLQMDFIHIAQFLT 724
W TL+ + PL +A RV+D+F +G E +FR GL +L++ + L+Q+D ++Q+
Sbjct: 273 SSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQVNQAELMQLDMEGMSQYFQ 332
Query: 725 K-LPEDITSEKLFSCIAAIQMQNSTKK 750
+ +P S + A Q++ + KK
Sbjct: 333 RVIPHQFDSCPDKLVLKAYQVKYNPKK 359
>gi|21687020 ecotropic viral integration site 5-like isoform 2 [Homo
sapiens]
Length = 794
Score = 111 bits (278), Expect = 2e-24
Identities = 95/387 (24%), Positives = 165/387 (42%), Gaps = 45/387 (11%)
Query: 368 EARTGRTCKPPPQSSRRKNFEFEPLSTTALILEDRPSNLPAKSVEEALRHRQEYDEMVAE 427
EA + TC P S E E L+ L ++R +KS+ R+ +
Sbjct: 14 EALSAPTCSPTSDSENLSPDELELLAK--LEEQNRLLEADSKSMRSMNGSRRNSGSSLVS 71
Query: 428 AKKREIKEAHKRKRIMKERFKQEENIASAMVIWINEILPNWEVMRSTRR--VRELWWQGL 485
+ +H + ++W I WE R + ++EL +G+
Sbjct: 72 SSSASSNLSHLEE--------------DTWILW-GRIANEWEEWRRRKEKLLKELIRKGI 116
Query: 486 PPSVRGKVWSLAVGNELNITPELYEIFLSRAKERWKSFSETSSENDTEGVSVADREASLE 545
P R VW L L K ++ + SS + +
Sbjct: 117 PHHFRAIVWQL-----------LCSATDMPVKNQYSELLKMSSPCE-------------K 152
Query: 546 LIKLDISRTFPSLYIFQ-KGGPYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLEE 604
LI+ DI+RT+P F+ + +VL +++ AY+ +VGY QG +FI +L++ + E
Sbjct: 153 LIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPE 212
Query: 605 ADAFIAFANLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLHFKSYSLTPDIYL 664
+AF F L+ + F+ + + FE +E L L HF+S S +Y
Sbjct: 213 EEAFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFRSQSFHTSMYA 272
Query: 665 IDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYEDILLQMDFIHIAQFLT 724
W TL+ + PL +A RV+D+F +G E +FR GL +L++ + L+Q+D ++Q+
Sbjct: 273 SSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQVNQAELMQLDMEGMSQYFQ 332
Query: 725 K-LPEDITSEKLFSCIAAIQMQNSTKK 750
+ +P S + A Q++ + KK
Sbjct: 333 RVIPHQFDSCPDKLVLKAYQVKYNPKK 359
>gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens]
Length = 828
Score = 110 bits (276), Expect = 4e-24
Identities = 74/266 (27%), Positives = 123/266 (46%), Gaps = 23/266 (8%)
Query: 460 WINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRAKER 519
W+ ++L WE ++T + ++G+P +RG+VW+L + E+ E S+ K R
Sbjct: 77 WL-KMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLL--EIPKMKEETRDLYSKLKHR 133
Query: 520 WKSFSETSSENDTEGVSVADREASLELIKLDISRTFPSLYIFQ-KGGPYHDVLHSILGAY 578
+ S + I LD++RTF +F+ + G L +L AY
Sbjct: 134 ARGCSP-----------------DIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAY 176
Query: 579 TCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKP--CQLAFFRVDHSMMLKYFA 636
+ Y +VGY QGMS I A+L++ + E DAF A L + P FF +L++
Sbjct: 177 SIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQE 236
Query: 637 TFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFL 696
E + LSKL H S + Y + W F + P L R+WD++ +GE L
Sbjct: 237 HHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVL 296
Query: 697 FRTGLGILRLYEDILLQMDFIHIAQF 722
IL+L++ L+++ + +F
Sbjct: 297 TAMSYTILKLHKKHLMKLSMEELVEF 322
>gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens]
Length = 845
Score = 110 bits (276), Expect = 4e-24
Identities = 74/266 (27%), Positives = 123/266 (46%), Gaps = 23/266 (8%)
Query: 460 WINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRAKER 519
W+ ++L WE ++T + ++G+P +RG+VW+L + E+ E S+ K R
Sbjct: 94 WL-KMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLL--EIPKMKEETRDLYSKLKHR 150
Query: 520 WKSFSETSSENDTEGVSVADREASLELIKLDISRTFPSLYIFQ-KGGPYHDVLHSILGAY 578
+ S + I LD++RTF +F+ + G L +L AY
Sbjct: 151 ARGCSP-----------------DIRQIDLDVNRTFRDHIMFRDRYGVKQQSLFHVLAAY 193
Query: 579 TCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKP--CQLAFFRVDHSMMLKYFA 636
+ Y +VGY QGMS I A+L++ + E DAF A L + P FF +L++
Sbjct: 194 SIYNTEVGYCQGMSQITALLLMYMNEEDAFWALVKLFSGPKHAMHGFFVQGFPKLLRFQE 253
Query: 637 TFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFL 696
E + LSKL H S + Y + W F + P L R+WD++ +GE L
Sbjct: 254 HHEKILNKFLSKLKQHLDSQEIYTSFYTMKWFFQCFLDRTPFTLNLRIWDIYIFEGERVL 313
Query: 697 FRTGLGILRLYEDILLQMDFIHIAQF 722
IL+L++ L+++ + +F
Sbjct: 314 TAMSYTILKLHKKHLMKLSMEELVEF 339
>gi|164519084 RAB GTPase activating protein 1 [Homo sapiens]
Length = 1069
Score = 108 bits (271), Expect = 1e-23
Identities = 78/276 (28%), Positives = 124/276 (44%), Gaps = 27/276 (9%)
Query: 463 EILPNWEVMRSTR--RVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRAKERW 520
E+L W + + R ++ L G+P ++RG+VW L G N E++
Sbjct: 543 ELLSKWHLNLNVRPKQLSSLVRNGVPEALRGEVWQLLAGCHNN----------DHLVEKY 592
Query: 521 KSFSETSSENDTEGVSVADREASLELIKLDISRTFPSL-YIFQKGGPYHDVLHSILGAYT 579
+ S D+ I DI+RTFP+ Y GG D L+ I AY+
Sbjct: 593 RILITKESPQDSA-------------ITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYS 639
Query: 580 CYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYFATFE 639
Y ++GY QG SF+AAVL+L++ E AF ++ F+ + + F E
Sbjct: 640 VYDEEIGYCQGQSFLAAVLLLHMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLE 699
Query: 640 VFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRT 699
+E + L+ HF SL +Y W TL++ PL + + D+ +G +F
Sbjct: 700 RLMQEYIPDLYNHFLDISLEAHMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNV 759
Query: 700 GLGILRLYEDILLQMDFIHIAQFL-TKLPEDITSEK 734
LG+L+ +D LL DF +F +LP+ SE+
Sbjct: 760 ALGLLKTSKDDLLLTDFEGALKFFRVQLPKRYRSEE 795
>gi|78217386 RAB GTPase activating protein 1-like isoform A [Homo
sapiens]
Length = 815
Score = 100 bits (250), Expect = 4e-21
Identities = 75/276 (27%), Positives = 119/276 (43%), Gaps = 27/276 (9%)
Query: 463 EILPNWEVMRSTRR--VRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRAKERW 520
E+L W R + L G+P ++R +VW L G N + L R +
Sbjct: 515 ELLGKWHSNLGARPKGLSTLVKSGVPEALRAEVWQLLAGCHDN------QAMLDRYR--- 565
Query: 521 KSFSETSSENDTEGVSVADREASLELIKLDISRTFPSL-YIFQKGGPYHDVLHSILGAYT 579
+ + A +I DI RTFP+ Y GG + L+ I AY+
Sbjct: 566 --------------ILITKDSAQESVITRDIHRTFPAHDYFKDTGGDGQESLYKICKAYS 611
Query: 580 CYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYFATFE 639
Y D+GY QG SF+AAVL+L++ E AF ++ +R + + F E
Sbjct: 612 VYDEDIGYCQGQSFLAAVLLLHMPEEQAFCVLVKIMYDYGLRDLYRNNFEDLHCKFYQLE 671
Query: 640 VFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRT 699
+E L L HF +L +Y W TL++ PL + + D+ +G +F
Sbjct: 672 RLMQEQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLCMVFHIIDLLLCEGLNIIFHV 731
Query: 700 GLGILRLYEDILLQMDFIHIAQFL-TKLPEDITSEK 734
L +L+ ++ LLQ DF +F +LP+ +E+
Sbjct: 732 ALALLKTSKEDLLQADFEGALKFFRVQLPKRYRAEE 767
>gi|13994322 TBC1 domain family, member 10A [Homo sapiens]
Length = 508
Score = 96.3 bits (238), Expect = 1e-19
Identities = 65/258 (25%), Positives = 120/258 (46%), Gaps = 43/258 (16%)
Query: 460 WINEILPNWE--VMRSTRRVRELWWQGLPPSVRGKVWSLAVGNELNITP---ELYEIFLS 514
W+ ++L NW+ + + +++R +G+PPS+RG+ W G ++ + + E+ +S
Sbjct: 86 WL-DMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELDMS 144
Query: 515 RAKERWKSFSETSSENDTEGVSVADREASLELIKLDISRTFPSLYIF-QKGGPYHDVLHS 573
+W L++I+ D+ R FP +F +GG L
Sbjct: 145 PGDPKW-----------------------LDVIERDLHRQFPFHEMFVSRGGHGQQDLFR 181
Query: 574 ILGAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPC------QLAFFRVD 627
+L AYT YRP+ GY Q + IAAVL++++ AF + K +L ++D
Sbjct: 182 VLKAYTLYRPEEGYCQAQAPIAAVLLMHMPAEQAFWCLVQICEKYLPGYYSEKLEAIQLD 241
Query: 628 HSMMLKYFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDV 687
++ ++LS+ + P +Y+ +W +S++LP RVWD+
Sbjct: 242 GEILFSLLQKVSPVAHKHLSR-------QKIDPLLYMTEWFMCAFSRTLPWSSVLRVWDM 294
Query: 688 FCRDGEEFLFRTGLGILR 705
F +G + +FR GL +L+
Sbjct: 295 FFCEGVKIIFRVGLVLLK 312
>gi|50658061 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
[Homo sapiens]
Length = 1168
Score = 95.9 bits (237), Expect = 1e-19
Identities = 88/373 (23%), Positives = 151/373 (40%), Gaps = 42/373 (11%)
Query: 364 QQEYEARTGRTCKPPPQSSRRKNF----EFEPLSTTALILEDRPSNLPAKSVEEALRHRQ 419
+Q+ R K SSR +++ E P S + ED P P EE R +
Sbjct: 662 RQQIFLRVATPQKACDSSSRYEDYSELGELPPRSPLEPVCEDGPFGPPP---EEKKRTSR 718
Query: 420 EYDEMVAEAKKREIKEAHKRKRIMKERFKQEENIASAMVIWINEILPN-------WEVMR 472
E E+ +A ++I K K + + + + + + EI P WE M
Sbjct: 719 ELRELWQKAILQQILLLRMEKENQKLQASENDLLNKRLKLDYEEITPCLKEVTTVWEKML 778
Query: 473 ST----------RRVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRAKERWKS 522
ST ++ QG+P RG++W FL+
Sbjct: 779 STPGRSKIKFDMEKMHSAVGQGVPRHHRGEIWK----------------FLAEQFHLKHQ 822
Query: 523 FSETSSENDTEGVSVADREASLE-LIKLDISRTFPSL-YIFQKGGPYHDVLHSILGAYTC 580
F D + + S + I +D+ RTFP+ Y + G L++IL AY+
Sbjct: 823 FPSKQQPKDVPYKELLKQLTSQQHAILIDLGRTFPTHPYFSAQLGAGQLSLYNILKAYSL 882
Query: 581 YRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYFATFEV 640
+VGY QG+SF+A +L+L++ E +AF L+ +R D ++
Sbjct: 883 LDQEVGYCQGLSFVAGILLLHMSEEEAFKMLKFLMFDMGLRKQYRPDMIILQIQMYQLSR 942
Query: 641 FFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTG 700
+ L+ H + + + P +Y W T+++ PL RV+D+ G E +F+
Sbjct: 943 LLHDYHRDLYNHLEEHEIGPSLYAAPWFLTMFASQFPLGFVARVFDMIFLQGTEVIFKVA 1002
Query: 701 LGILRLYEDILLQ 713
L +L ++ ++LQ
Sbjct: 1003 LSLLGSHKPLILQ 1015
>gi|114688046 TBC1 domain family, member 4 [Homo sapiens]
Length = 1298
Score = 91.7 bits (226), Expect = 2e-18
Identities = 89/368 (24%), Positives = 155/368 (42%), Gaps = 29/368 (7%)
Query: 379 PQSSRRKNFEFEPLSTTALILEDRPSNLPAKSVEEALRH------RQEYDEMVAEAKKRE 432
P S E EPL L ED P + + + LR Q+ + E + ++
Sbjct: 804 PLSPLSPTMEEEPL-VVFLSGEDDPEKIEERKKSKELRSLWRKAIHQQILLLRMEKENQK 862
Query: 433 IKEAHKRKRIMKERFKQEENIA---SAMVIWINEILPNWEVMRSTRR-VRELWWQGLPPS 488
++ + + K + EE A ++ W ++L +R + L +G+P S
Sbjct: 863 LEASRDELQSRKVKLDYEEVGACQKEVLITWDKKLLNCRAKIRCDMEDIHTLLKEGVPKS 922
Query: 489 VRGKVWSLAVGNELNITPELYEIFLSRAKERWKSFSETSSENDTEGVSVADREASLELIK 548
RG++W L + L ++ + S+ E + A I
Sbjct: 923 RRGEIWQF-----LALQYRLRHRLPNKQQPPDISYKELLKQ----------LTAQQHAIL 967
Query: 549 LDISRTFPSL-YIFQKGGPYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLEEADA 607
+D+ RTFP+ Y + GP L ++L AY+ +VGY QG+SF+A VL+L++ E A
Sbjct: 968 VDLGRTFPTHPYFSVQLGPGQLSLFNLLKAYSLLDKEVGYCQGISFVAGVLLLHMSEEQA 1027
Query: 608 FIAFANLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDW 667
F L+ +R D + + L+ H + ++P +Y W
Sbjct: 1028 FEMLKFLMYDLGFRKQYRPDMMSLQIQMYQLSRLLHDYHRDLYNHLEENEISPSLYAAPW 1087
Query: 668 IFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYEDILLQMD-FIHIAQFL-TK 725
TL++ L RV+D+ G E +F+ L +L E ++++ + F +I +FL
Sbjct: 1088 FLTLFASQFSLGFVARVFDIIFLQGTEVIFKVALSLLSSQETLIMECESFENIVEFLKNT 1147
Query: 726 LPEDITSE 733
LP+ TSE
Sbjct: 1148 LPDMNTSE 1155
>gi|38348348 TBC1 domain family, member 10C [Homo sapiens]
Length = 446
Score = 89.4 bits (220), Expect = 1e-17
Identities = 68/255 (26%), Positives = 111/255 (43%), Gaps = 35/255 (13%)
Query: 460 WINEILPNWEVMRSTR--RVRELWWQGLPPSVRGKVWSLAVGNEL---NITPELYEIFLS 514
W+ E+ +WE S R +V+ +G+P ++R + W L G + N E+ +
Sbjct: 67 WV-EMTSHWEKTMSRRYKKVKMQCRKGIPSALRARCWPLLCGAHVCQKNSPGTYQELAEA 125
Query: 515 RAKERWKSFSETSSENDTEGVSVADREASLELIKLDISRTFP--SLYIFQKGGPYHDVLH 572
+W +E I D+ R FP +++ +G +L
Sbjct: 126 PGDPQW-----------------------METIGRDLHRQFPLHEMFVSPQGHGQQGLLQ 162
Query: 573 SILGAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMML 632
+L AYT YRP+ GY Q +AAVL+++L +AF + L + H +
Sbjct: 163 -VLKAYTLYRPEQGYCQAQGPVAAVLLMHLPPEEAFWCLVQICE--VYLPGYYGPHMEAV 219
Query: 633 KYFA-TFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRD 691
+ A F L + H + + P +YL +W L+++SLP RVWD F +
Sbjct: 220 RLDAEVFMALLRRLLPHVHKHLQQVGVGPLLYLPEWFLCLFARSLPFPTVLRVWDAFLSE 279
Query: 692 GEEFLFRTGLGILRL 706
G LFR GL ++RL
Sbjct: 280 GARVLFRVGLTLVRL 294
>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
Length = 808
Score = 87.8 bits (216), Expect = 3e-17
Identities = 70/252 (27%), Positives = 116/252 (46%), Gaps = 31/252 (12%)
Query: 460 WINEILPNWEVMRSTR--RVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRAK 517
W+ ++ NW+ S R +V+ +G+P S+R K W +LS +K
Sbjct: 335 WL-DMFSNWDKWLSRRFQKVKLRCRKGIPSSLRAKAWQ----------------YLSNSK 377
Query: 518 ERWKSFSETSSENDTEGVSVADREASLELIKLDISRTFPSLYIFQ-KGGPYHDVLHSILG 576
E E + E L++I+ D+ R FP +F +GG L+ IL
Sbjct: 378 E----LLEQNPGKFEELERAPGDPKWLDVIEKDLHRQFPFHEMFAARGGHGQQDLYRILK 433
Query: 577 AYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYFA 636
AYT YRPD GY Q + +AAVL++++ AF + +K + ++ L
Sbjct: 434 AYTIYRPDEGYCQAQAPVAAVLLMHMPAEQAFWCLVQICDKYLPGYYSAGLEAIQLDG-- 491
Query: 637 TFEVFFE--ENLSKL-FLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGE 693
E+FF S L H + + P +Y+ +W +++++LP RVWD+F +G
Sbjct: 492 --EIFFALLRRASPLAHRHLRRQRIDPVLYMTEWFMCIFARTLPWASVLRVWDMFFCEGV 549
Query: 694 EFLFRTGLGILR 705
+ +FR L +LR
Sbjct: 550 KIIFRVALVLLR 561
>gi|194018478 TBC1 domain family, member 2B isoform a [Homo sapiens]
Length = 963
Score = 81.3 bits (199), Expect = 3e-15
Identities = 77/317 (24%), Positives = 130/317 (41%), Gaps = 34/317 (10%)
Query: 420 EYD----EMVAEAKKREIKEAHKRKRIMKERFKQEENIASAMVIWINEILP--NWEVMRS 473
EYD V E + E A R +K + E S V W N N E+M S
Sbjct: 593 EYDIYGFRTVPEDDEEEKLVAKVRALDLKTLYLTENQEVSTGVKWENYFASTVNREMMCS 652
Query: 474 TRRVRELWWQGLPPSVRGKVWSLAVGNEL-----NITPELYEIFLSRAKERWKSFSETSS 528
++ L G+P R KVW V N P ++ L +A E+ S+
Sbjct: 653 PE-LKNLIRAGIPHEHRSKVWKWCVDRHTRKFKDNTEPGHFQTLLQKALEKQNPASKQ-- 709
Query: 529 ENDTEGVSVADREASLELIKLDISRTFPSLYIFQ-KGGPYHDVLHSILGAYTCYRPDVGY 587
I+LD+ RT P+ + L ++L A++ PD+GY
Sbjct: 710 ------------------IELDLLRTLPNNKHYSCPTSEGIQKLRNVLLAFSWRNPDIGY 751
Query: 588 VQGMSFIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLS 647
QG++ + AV +L LE+ DAF ++ ++ F E L
Sbjct: 752 CQGLNRLVAVALLYLEQEDAFWCLVTIVEVFMPRDYYTKTLLGSQVDQRVFRDLMSEKLP 811
Query: 648 KLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLY 707
+L HF+ Y + + +W ++ S+ D+ ++WD F +G + +FR L + +
Sbjct: 812 RLHGHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRFALALFKYK 871
Query: 708 EDILLQM-DFIHIAQFL 723
E+ +L++ D + I ++L
Sbjct: 872 EEEILKLQDSMSIFKYL 888
>gi|194018476 TBC1 domain family, member 2B isoform b [Homo sapiens]
Length = 914
Score = 81.3 bits (199), Expect = 3e-15
Identities = 77/317 (24%), Positives = 130/317 (41%), Gaps = 34/317 (10%)
Query: 420 EYD----EMVAEAKKREIKEAHKRKRIMKERFKQEENIASAMVIWINEILP--NWEVMRS 473
EYD V E + E A R +K + E S V W N N E+M S
Sbjct: 593 EYDIYGFRTVPEDDEEEKLVAKVRALDLKTLYLTENQEVSTGVKWENYFASTVNREMMCS 652
Query: 474 TRRVRELWWQGLPPSVRGKVWSLAVGNEL-----NITPELYEIFLSRAKERWKSFSETSS 528
++ L G+P R KVW V N P ++ L +A E+ S+
Sbjct: 653 PE-LKNLIRAGIPHEHRSKVWKWCVDRHTRKFKDNTEPGHFQTLLQKALEKQNPASKQ-- 709
Query: 529 ENDTEGVSVADREASLELIKLDISRTFPSLYIFQ-KGGPYHDVLHSILGAYTCYRPDVGY 587
I+LD+ RT P+ + L ++L A++ PD+GY
Sbjct: 710 ------------------IELDLLRTLPNNKHYSCPTSEGIQKLRNVLLAFSWRNPDIGY 751
Query: 588 VQGMSFIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLS 647
QG++ + AV +L LE+ DAF ++ ++ F E L
Sbjct: 752 CQGLNRLVAVALLYLEQEDAFWCLVTIVEVFMPRDYYTKTLLGSQVDQRVFRDLMSEKLP 811
Query: 648 KLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLY 707
+L HF+ Y + + +W ++ S+ D+ ++WD F +G + +FR L + +
Sbjct: 812 RLHGHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRFALALFKYK 871
Query: 708 EDILLQM-DFIHIAQFL 723
E+ +L++ D + I ++L
Sbjct: 872 EEEILKLQDSMSIFKYL 888
>gi|38570101 TBC1 domain family, member 8B (with GRAM domain)
isoform a [Homo sapiens]
Length = 1120
Score = 77.0 bits (188), Expect = 6e-14
Identities = 64/244 (26%), Positives = 106/244 (43%), Gaps = 25/244 (10%)
Query: 471 MRSTRRVRELWWQGLPPSVRGKVWSLAVG--NELNITPELYEIFLSRAKERWKSFSETSS 528
M T++ R+L +G+P ++RG++W L G N++ P+ Y + +
Sbjct: 474 MFRTKKTRDLVVRGIPETLRGELWMLFSGAVNDMATNPDYYTEVVEQ------------- 520
Query: 529 ENDTEGVSVADREASLELIKLDISRTFPSLYIFQKGGPYHDVLHSILGAYTCYRPDVGYV 588
S+ + E I+ D+ R+ P FQ L +L AY P +GY
Sbjct: 521 -------SLGTCNLATEEIERDLRRSLPEHPAFQSDTGI-SALRRVLTAYAYRNPKIGYC 572
Query: 589 QGMSFIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLSK 648
Q M+ + +VL+L +E +AF + + F R ++ A FE ++L +
Sbjct: 573 QAMNILTSVLLLYAKEEEAFWLLVAVCERMLPDYFNRRIIGALVDQ-AVFEELIRDHLPQ 631
Query: 649 LFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYE 708
L H + + L W TL+ LP++ A V D F DG + + + GL IL
Sbjct: 632 LTEHMTDMTFFSSVSL-SWFLTLFISVLPIESAVNVVDCFFYDGIKAILQLGLAILDYNL 690
Query: 709 DILL 712
D LL
Sbjct: 691 DKLL 694
>gi|29648315 small G protein signaling modulator 3 [Homo sapiens]
Length = 749
Score = 76.3 bits (186), Expect = 1e-13
Identities = 62/269 (23%), Positives = 112/269 (41%), Gaps = 20/269 (7%)
Query: 474 TRRVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRAKERWKSFSETSSENDTE 533
+ ++R L G+P +R ++W G L + + S+ E +
Sbjct: 104 SEKLRSLVLAGIPHGMRPQLWMRLSGA------------LQKKRNSELSYREIVKNSSN- 150
Query: 534 GVSVADREASLELIKLDISRTFPSLYIFQKGGPYH-DVLHSILGAYTCYRPDVGYVQGMS 592
D + + I+ D+ RT PS F G L +L A P++GY QG
Sbjct: 151 -----DETIAAKQIEKDLLRTMPSNACFASMGSIGVPRLRRVLRALAWLYPEIGYCQGTG 205
Query: 593 FIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLH 652
+AA L+L LEE DAF + ++ ++F + + L +L
Sbjct: 206 MVAACLLLFLEEEDAFWMMSAIIEDLLPASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKL 265
Query: 653 FKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYEDILL 712
+ + + + + W T ++ + + L R+WD+F +G LF+ LG+L L E+ L+
Sbjct: 266 LQEHDIELSLITLHWFLTAFASVVDIKLLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELI 325
Query: 713 QMD-FIHIAQFLTKLPEDITSEKLFSCIA 740
Q + I L+ +P + +L +A
Sbjct: 326 QSENSASIFNTLSDIPSQMEDAELLLGVA 354
>gi|90577185 TBC1 domain family member 3C [Homo sapiens]
Length = 549
Score = 73.2 bits (178), Expect = 9e-13
Identities = 66/243 (27%), Positives = 110/243 (45%), Gaps = 29/243 (11%)
Query: 460 WINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVG-NELNI-TPELYEIFLSRAK 517
W+ ++L +WE +S+R++ + ++G+P ++RG +WS+ + E+ + P Y+I K
Sbjct: 78 WV-DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIM----K 132
Query: 518 ERWKSFSETSSENDTEGVSVADREASLELIKLDISRTFPSLYIFQK--GGPYHDVLHSIL 575
E+ K SE ++ I DIS T F+ G ++LH +L
Sbjct: 133 EKGKRSSE-----------------HIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILL 175
Query: 576 GAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLL--NKPCQLAFFRVDHSMMLK 633
AY Y P+VGY + +S IAA+ +L L E DAF A LL + F + +
Sbjct: 176 -AYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQG 234
Query: 634 YFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGE 693
E + SK H L + + + + L L R+WDV+ +GE
Sbjct: 235 LQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGE 294
Query: 694 EFL 696
+ L
Sbjct: 295 QAL 297
>gi|149999613 TBC1 domain family, member 3B [Homo sapiens]
Length = 549
Score = 71.6 bits (174), Expect = 3e-12
Identities = 65/243 (26%), Positives = 109/243 (44%), Gaps = 29/243 (11%)
Query: 460 WINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVG-NELNI-TPELYEIFLSRAK 517
W+ ++L +WE +S+R++ + ++G+P ++RG +WS+ + E+ + P Y+I K
Sbjct: 78 WV-DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIM----K 132
Query: 518 ERWKSFSETSSENDTEGVSVADREASLELIKLDISRTFPSLYIFQK--GGPYHDVLHSIL 575
E+ K SE ++ I DIS T F+ G ++LH +L
Sbjct: 133 EKGKRSSE-----------------HIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILL 175
Query: 576 GAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLL--NKPCQLAFFRVDHSMMLK 633
AY Y P+VGY + +S IAA+ +L E DAF A LL + F + +
Sbjct: 176 -AYEEYNPEVGYCRDLSHIAALFLLYFPEEDAFWALVQLLASERHSLQGFHSPNGGTVQG 234
Query: 634 YFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGE 693
E + SK H L + + + + L L R+WDV+ +GE
Sbjct: 235 LQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGE 294
Query: 694 EFL 696
+ L
Sbjct: 295 QAL 297
>gi|226693407 TBC1 domain family, member 3H [Homo sapiens]
Length = 549
Score = 71.2 bits (173), Expect = 3e-12
Identities = 65/243 (26%), Positives = 109/243 (44%), Gaps = 29/243 (11%)
Query: 460 WINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVG-NELNI-TPELYEIFLSRAK 517
W+ ++L +WE +S+R++ + ++G+P ++RG +WS+ + E+ + P Y+I K
Sbjct: 78 WV-DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIM----K 132
Query: 518 ERWKSFSETSSENDTEGVSVADREASLELIKLDISRTFPSLYIFQK--GGPYHDVLHSIL 575
E+ K SE ++ I DIS T F+ G ++LH +L
Sbjct: 133 EKGKRSSE-----------------HIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILL 175
Query: 576 GAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLL--NKPCQLAFFRVDHSMMLK 633
AY Y P+VGY + +S IAA+ +L L E DAF A LL + F + +
Sbjct: 176 -AYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQG 234
Query: 634 YFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGE 693
E + K H L + + + + L L R+WDV+ +GE
Sbjct: 235 LQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGE 294
Query: 694 EFL 696
+ L
Sbjct: 295 QAL 297
>gi|14149985 TBC1 domain family, member 3F [Homo sapiens]
Length = 549
Score = 71.2 bits (173), Expect = 3e-12
Identities = 64/243 (26%), Positives = 109/243 (44%), Gaps = 29/243 (11%)
Query: 460 WINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVGNE-LNI-TPELYEIFLSRAK 517
W+ ++L +WE +S+R++ + ++G+P ++RG +WS+ + E + + P Y+I K
Sbjct: 78 WV-DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIM----K 132
Query: 518 ERWKSFSETSSENDTEGVSVADREASLELIKLDISRTFPSLYIFQK--GGPYHDVLHSIL 575
E+ K SE ++ I D+S T F+ G ++LH +L
Sbjct: 133 EKGKKSSE-----------------HIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILL 175
Query: 576 GAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLL--NKPCQLAFFRVDHSMMLK 633
AY Y P+VGY + +S IAA+ +L L E DAF A LL + F + +
Sbjct: 176 -AYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQG 234
Query: 634 YFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGE 693
E + K H L + + + + L L R+WDV+ +GE
Sbjct: 235 LQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGE 294
Query: 694 EFL 696
+ L
Sbjct: 295 QAL 297
>gi|157502205 TBC1 domain family, member 3G [Homo sapiens]
Length = 549
Score = 71.2 bits (173), Expect = 3e-12
Identities = 65/243 (26%), Positives = 109/243 (44%), Gaps = 29/243 (11%)
Query: 460 WINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVG-NELNI-TPELYEIFLSRAK 517
W+ ++L +WE +S+R++ + ++G+P ++RG +WS+ + E+ + P Y+I K
Sbjct: 78 WV-DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIM----K 132
Query: 518 ERWKSFSETSSENDTEGVSVADREASLELIKLDISRTFPSLYIFQK--GGPYHDVLHSIL 575
E+ K SE ++ I DIS T F+ G ++LH +L
Sbjct: 133 EKGKRSSE-----------------HIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILL 175
Query: 576 GAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLL--NKPCQLAFFRVDHSMMLK 633
AY Y P+VGY + +S IAA+ +L L E DAF A LL + F + +
Sbjct: 176 -AYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQG 234
Query: 634 YFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGE 693
E + K H L + + + + L L R+WDV+ +GE
Sbjct: 235 LQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGE 294
Query: 694 EFL 696
+ L
Sbjct: 295 QAL 297
>gi|183583565 TBC1 domain family, member 3 [Homo sapiens]
Length = 549
Score = 70.9 bits (172), Expect = 4e-12
Identities = 64/243 (26%), Positives = 109/243 (44%), Gaps = 29/243 (11%)
Query: 460 WINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVG-NELNI-TPELYEIFLSRAK 517
W+ ++L +WE +S+R++ + ++G+P ++RG +WS+ + E+ + P Y+I K
Sbjct: 78 WV-DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIM----K 132
Query: 518 ERWKSFSETSSENDTEGVSVADREASLELIKLDISRTFPSLYIFQK--GGPYHDVLHSIL 575
E+ K SE ++ I D+S T F+ G ++LH +L
Sbjct: 133 EKGKRSSE-----------------HIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILL 175
Query: 576 GAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLL--NKPCQLAFFRVDHSMMLK 633
AY Y P+VGY + +S IAA+ +L L E DAF A LL + F + +
Sbjct: 176 -AYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQG 234
Query: 634 YFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGE 693
E + K H L + + + + L L R+WDV+ +GE
Sbjct: 235 LQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGE 294
Query: 694 EFL 696
+ L
Sbjct: 295 QAL 297
>gi|183583567 TBC1 domain family, member 3E [Homo sapiens]
Length = 549
Score = 70.9 bits (172), Expect = 4e-12
Identities = 64/243 (26%), Positives = 109/243 (44%), Gaps = 29/243 (11%)
Query: 460 WINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVG-NELNI-TPELYEIFLSRAK 517
W+ ++L +WE +S+R++ + ++G+P ++RG +WS+ + E+ + P Y+I K
Sbjct: 78 WV-DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIM----K 132
Query: 518 ERWKSFSETSSENDTEGVSVADREASLELIKLDISRTFPSLYIFQK--GGPYHDVLHSIL 575
E+ K SE ++ I D+S T F+ G ++LH +L
Sbjct: 133 EKGKRSSE-----------------HIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILL 175
Query: 576 GAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLL--NKPCQLAFFRVDHSMMLK 633
AY Y P+VGY + +S IAA+ +L L E DAF A LL + F + +
Sbjct: 176 -AYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQG 234
Query: 634 YFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGE 693
E + K H L + + + + L L R+WDV+ +GE
Sbjct: 235 LQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGE 294
Query: 694 EFL 696
+ L
Sbjct: 295 QAL 297
>gi|183583563 TBC1 domain family, member 3D [Homo sapiens]
Length = 549
Score = 70.9 bits (172), Expect = 4e-12
Identities = 64/243 (26%), Positives = 109/243 (44%), Gaps = 29/243 (11%)
Query: 460 WINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVG-NELNI-TPELYEIFLSRAK 517
W+ ++L +WE +S+R++ + ++G+P ++RG +WS+ + E+ + P Y+I K
Sbjct: 78 WV-DMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIM----K 132
Query: 518 ERWKSFSETSSENDTEGVSVADREASLELIKLDISRTFPSLYIFQK--GGPYHDVLHSIL 575
E+ K SE ++ I D+S T F+ G ++LH +L
Sbjct: 133 EKGKRSSE-----------------HIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILL 175
Query: 576 GAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLL--NKPCQLAFFRVDHSMMLK 633
AY Y P+VGY + +S IAA+ +L L E DAF A LL + F + +
Sbjct: 176 -AYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQG 234
Query: 634 YFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGE 693
E + K H L + + + + L L R+WDV+ +GE
Sbjct: 235 LQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGE 294
Query: 694 EFL 696
+ L
Sbjct: 295 QAL 297
>gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Homo
sapiens]
Length = 1266
Score = 69.3 bits (168), Expect = 1e-11
Identities = 62/244 (25%), Positives = 103/244 (42%), Gaps = 25/244 (10%)
Query: 471 MRSTRRVRELWWQGLPPSVRGKVWSLAVG--NELNITPELYEIFLSRAKERWKSFSETSS 528
M T + REL +G+P S+RG++W L G NE P YE + ++ ++ +E
Sbjct: 502 MYRTEKTRELVLKGIPESMRGELWLLLSGAINEKATHPGYYEDLVEKSMGKYNLATEE-- 559
Query: 529 ENDTEGVSVADREASLELIKLDISRTFPSLYIFQKGGPYHDVLHSILGAYTCYRPDVGYV 588
I+ D+ R+ P FQ L +L AY P++GY
Sbjct: 560 ------------------IERDLHRSLPEHPAFQNEMGIA-ALRRVLTAYAFRNPNIGYC 600
Query: 589 QGMSFIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLSK 648
Q M+ + +VL+L +E +AF L + ++ L FE + + +
Sbjct: 601 QAMNIVTSVLLLYAKEEEAFWLLVALCERMLP-DYYNTRVVGALVDQGVFEELARDYVPQ 659
Query: 649 LFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYE 708
L+ + + I L W TL+ +P + A V D F +G + +F+ L +L
Sbjct: 660 LYDCMQDLGVISTISL-SWFLTLFLSVMPFESAVVVVDCFFYEGIKVIFQLALAVLDANV 718
Query: 709 DILL 712
D LL
Sbjct: 719 DKLL 722
>gi|222352143 TBC1 domain family, member 2 [Homo sapiens]
Length = 917
Score = 67.8 bits (164), Expect = 4e-11
Identities = 66/303 (21%), Positives = 123/303 (40%), Gaps = 34/303 (11%)
Query: 477 VRELWWQGLPPSVRGKVWSLAVGNELNI--TPELYEIFLSRAKERWKSFSETSSENDTEG 534
+++L G+P R +VW V + TP Y+ LSR + R
Sbjct: 618 LKQLLRAGVPREHRPRVWRWLVHLRVQHLHTPGCYQELLSRGQAR--------------- 662
Query: 535 VSVADREASLELIKLDISRTFPSLYIFQ-KGGPYHDVLHSILGAYTCYRPDVGYVQGMSF 593
+ I+LD++RTFP+ F + D L +L A++ P +GY QG++
Sbjct: 663 -----EHPAARQIELDLNRTFPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNR 717
Query: 594 IAAVLILNLEEAD-AFIAFANLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLH 652
+AA+ +L LEE + AF ++ ++ + + E L +L H
Sbjct: 718 LAAIALLVLEEEESAFWCLVAIVETIMPADYYCNTLTASQVDQRVLQDLLSEKLPRLMAH 777
Query: 653 FKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYEDILL 712
+ + + +W +++ SL ++ RVWD F +G ++ ++IL
Sbjct: 778 LGQHHVDLSLVTFNWFLVVFADSLISNILLRVWDAFLYEGTKY----------NEKEILR 827
Query: 713 QMDFIHIAQFLTKLPEDITSEKLFSCIAAIQMQNSTKKWTQVFASVMKDIKEGDKNSSPA 772
+ + I Q+L + I++ + IA M K + V ++ E +
Sbjct: 828 LQNGLEIYQYLRFFTKTISNSRKLMNIAFNDMNPFRMKQLRQLRMVHRERLEAELRELEQ 887
Query: 773 LKS 775
LK+
Sbjct: 888 LKA 890
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,530,514
Number of Sequences: 37866
Number of extensions: 2019574
Number of successful extensions: 17339
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 124
Number of HSP's successfully gapped in prelim test: 466
Number of HSP's that attempted gapping in prelim test: 15201
Number of HSP's gapped (non-prelim): 2136
length of query: 775
length of database: 18,247,518
effective HSP length: 110
effective length of query: 665
effective length of database: 14,082,258
effective search space: 9364701570
effective search space used: 9364701570
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.