BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|148792970 TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa [Homo sapiens] (862 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|148792970 TAF4b RNA polymerase II, TATA box binding protein (... 1650 0.0 gi|110832843 TBP-associated factor 4 [Homo sapiens] 352 8e-97 gi|91982772 mucin 17 [Homo sapiens] 82 2e-15 gi|116284392 mucin 2 precursor [Homo sapiens] 70 8e-12 gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 64 8e-10 gi|38788274 bromodomain PHD finger transcription factor isoform ... 64 8e-10 gi|167736355 mucin 4 isoform a [Homo sapiens] 63 1e-09 gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens] 63 1e-09 gi|98986457 host cell factor 1 [Homo sapiens] 62 2e-09 gi|38261962 activating transcription factor 7 interacting protei... 62 3e-09 gi|19923559 EMSY protein [Homo sapiens] 60 9e-09 gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 60 1e-08 gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] 59 1e-08 gi|161019170 mucin 5AC [Homo sapiens] 57 6e-08 gi|239757995 PREDICTED: similar to hCG1747327, partial [Homo sap... 57 6e-08 gi|239752523 PREDICTED: intestinal mucin-like, partial [Homo sap... 57 7e-08 gi|151301154 mucin 6, gastric [Homo sapiens] 56 1e-07 gi|219802034 nuclear factor related to kappaB binding protein is... 55 4e-07 gi|23346420 nuclear factor related to kappaB binding protein iso... 55 4e-07 gi|28329416 acute myelogenous leukemia 1 translocation 1 protein... 54 5e-07 gi|4757916 acute myelogenous leukemia 1 translocation 1 protein ... 54 5e-07 gi|163965366 nascent polypeptide-associated complex alpha subuni... 54 5e-07 gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 53 1e-06 gi|19111150 angiomotin isoform 2 [Homo sapiens] 53 1e-06 gi|166064029 angiomotin isoform 1 [Homo sapiens] 53 1e-06 gi|28329422 acute myelogenous leukemia 1 translocation 1 protein... 53 1e-06 gi|28329419 acute myelogenous leukemia 1 translocation 1 protein... 53 1e-06 gi|112421108 capicua homolog [Homo sapiens] 53 1e-06 gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 52 2e-06 gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens] 52 2e-06 >gi|148792970 TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa [Homo sapiens] Length = 862 Score = 1650 bits (4274), Expect = 0.0 Identities = 862/862 (100%), Positives = 862/862 (100%) Query: 1 MPAGLTEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQ 60 MPAGLTEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQ Sbjct: 1 MPAGLTEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQ 60 Query: 61 PLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIK 120 PLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIK Sbjct: 61 PLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIK 120 Query: 121 SNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKK 180 SNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKK Sbjct: 121 SNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKK 180 Query: 181 LAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLK 240 LAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLK Sbjct: 181 LAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLK 240 Query: 241 AENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEA 300 AENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEA Sbjct: 241 AENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEA 300 Query: 301 EEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTT 360 EEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTT Sbjct: 301 EEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTT 360 Query: 361 VTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAA 420 VTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAA Sbjct: 361 VTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAA 420 Query: 421 TGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAIC 480 TGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAIC Sbjct: 421 TGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAIC 480 Query: 481 LPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNE 540 LPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNE Sbjct: 481 LPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNE 540 Query: 541 KQVTTISHSSTLTIQKCGQKTMPVNTIIPTSQFPPASILKQITLPGNKILSLQASPTQKN 600 KQVTTISHSSTLTIQKCGQKTMPVNTIIPTSQFPPASILKQITLPGNKILSLQASPTQKN Sbjct: 541 KQVTTISHSSTLTIQKCGQKTMPVNTIIPTSQFPPASILKQITLPGNKILSLQASPTQKN 600 Query: 601 RIKENVTSCFRDEDDINDVTSMAGVNLNEENACILATNSELVGTLIQSCKDEPFLFIGAL 660 RIKENVTSCFRDEDDINDVTSMAGVNLNEENACILATNSELVGTLIQSCKDEPFLFIGAL Sbjct: 601 RIKENVTSCFRDEDDINDVTSMAGVNLNEENACILATNSELVGTLIQSCKDEPFLFIGAL 660 Query: 661 QKRILDIGKKHDITELNSDAVNLISQATQERLRGLLEKLTAIAQHRMTTYKASENYILCS 720 QKRILDIGKKHDITELNSDAVNLISQATQERLRGLLEKLTAIAQHRMTTYKASENYILCS Sbjct: 661 QKRILDIGKKHDITELNSDAVNLISQATQERLRGLLEKLTAIAQHRMTTYKASENYILCS 720 Query: 721 DTRSQLKFLEKLDQLEKQRKDLEEREMLLKAAKSRSNKEDPEQLRLKQKAKELQQLELAQ 780 DTRSQLKFLEKLDQLEKQRKDLEEREMLLKAAKSRSNKEDPEQLRLKQKAKELQQLELAQ Sbjct: 721 DTRSQLKFLEKLDQLEKQRKDLEEREMLLKAAKSRSNKEDPEQLRLKQKAKELQQLELAQ 780 Query: 781 IQHRDANLTALAAIGPRKKRPLESGIEGLKDNLLASGTSSLTATKQLHRPRITRICLRDL 840 IQHRDANLTALAAIGPRKKRPLESGIEGLKDNLLASGTSSLTATKQLHRPRITRICLRDL Sbjct: 781 IQHRDANLTALAAIGPRKKRPLESGIEGLKDNLLASGTSSLTATKQLHRPRITRICLRDL 840 Query: 841 IFCMEQEREMKYSRALYLALLK 862 IFCMEQEREMKYSRALYLALLK Sbjct: 841 IFCMEQEREMKYSRALYLALLK 862 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 352 bits (903), Expect = 8e-97 Identities = 310/931 (33%), Positives = 420/931 (45%), Gaps = 138/931 (14%) Query: 15 AAVSASGTVTMAPAGALPVRVESTPVALGAVTKAP--VSVCVEPTASQPLRSPVGTLVTK 72 AA A V PA LP+ P A G V + P V P + P SP Sbjct: 210 AAAPAVSLVNNGPAALLPL---PKPAAPGTVIQTPPFVGAAAPPAPAAP--SP------P 258 Query: 73 VAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLVSPQ 132 AP A P + P PAP +A + A PP ++G +P Sbjct: 259 AAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPA 318 Query: 133 QTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIG--TTVVT 190 A + ++ +P P V S + + + A + LA G +T + Sbjct: 319 -----AGGPAGVSGQPG-PGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAAS 372 Query: 191 TVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGA-SSTPSNEPNLKAENSAAVQI 249 V P+ ++ P +V PG P T L + GA + + S P ++ ++ Sbjct: 373 MVIGPTMQGALPSPAAVPPPAPGTP----TGLPKGAAGAVTQSLSRTPTA---TTSGIRA 425 Query: 250 NLSPTML--------ENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAE 301 L+PT+L +N +NF Q P V+ QLL + + Sbjct: 426 TLTPTVLAPRLPQPPQNPTNIQNF------------QLPPGMVLVRSENGQLL---MIPQ 470 Query: 302 EFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTV 361 + ++ + + PQ + P R P S +Q Q +IA T Sbjct: 471 QALAQMQAQAHAQPQTTMAP---------RPATPTSAPPVQISTVQAPGTPIIARQVTP- 520 Query: 362 TTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVG-AKAGVVTLHSVGPTAA 420 TT + ++ + AT R+ VQ L G A G T G Sbjct: 521 ------TTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQR 574 Query: 421 T--GGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTL-------------- 464 T G TT + +T + + T + L + TA + Sbjct: 575 TVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEA 634 Query: 465 -------------------------SLPAVTFGETSGAAICLPSVK---PVVSSAGTTSD 496 SLPA+ AA S + P S A T Sbjct: 635 EDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQPPPPTSQATTALT 694 Query: 497 KPVIGTPVQ---------IKLAQPGPVLS--QPA--GIPQAVQVKQLVVQQPSGGNE--- 540 V+ + VQ + A PVLS QP G+ + Q LV+QQP Sbjct: 695 AVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQGQPTPLVIQQPPKPGALIR 754 Query: 541 -KQVTTISHSSTLTIQKCGQKTMPVNTIIPTSQFPPASILKQITLPGNKILSL---QASP 596 QVT Q + + I + P ++K LPG K LS QA+ Sbjct: 755 PPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPLQPVPVVKPAVLPGTKALSAVSAQAAA 814 Query: 597 TQKNRIKENVTSCFRDEDDINDVTSMAGVNLNEENACILATNSELVGTLIQSCKDEPFLF 656 QKN++KE FRD+DDINDV SMAGVNL+EE+A ILATNSELVGTL +SCKDE FL Sbjct: 815 AQKNKLKEPGGGSFRDDDDINDVASMAGVNLSEESARILATNSELVGTLTRSCKDETFLL 874 Query: 657 IGALQKRILDIGKKHDITELNSDAVNLISQATQERLRGLLEKLTAIAQHRMTTYKASENY 716 LQ+RIL+IGKKH ITEL+ D V+ +S ATQ+RL+ L+EK++ AQ + +YK + Y Sbjct: 875 QAPLQRRILEIGKKHGITELHPDVVSYVSHATQQRLQNLVEKISETAQQKNFSYKDDDRY 934 Query: 717 ILCSDTRSQLKFLEKLDQLEKQRKDLEEREMLLKAAKSRSNKEDPEQLRLKQKAKELQQL 776 SD R+QLKF E+LDQ+EKQRKD +ERE+L++AAKSRS +EDPEQLRLKQKAKE+QQ Sbjct: 935 EQASDVRAQLKFFEQLDQIEKQRKDEQEREILMRAAKSRSRQEDPEQLRLKQKAKEMQQQ 994 Query: 777 ELAQIQHRDANLTALAAIGPRKKRPLE-----SGIEGLKDNLLASGTSSLTATKQLHRPR 831 ELAQ++ RDANLTALAAIGPRKKR ++ SG EG + G+S + +Q R R Sbjct: 995 ELAQMRQRDANLTALAAIGPRKKRKVDCPGPGSGAEGSGPGSVVPGSSGVGTPRQFTRQR 1054 Query: 832 ITRICLRDLIFCMEQEREMKYSRALYLALLK 862 ITR+ LRDLIFC+E ERE +S LY A LK Sbjct: 1055 ITRVNLRDLIFCLENERETSHSLLLYKAFLK 1085 Score = 200 bits (508), Expect = 5e-51 Identities = 176/546 (32%), Positives = 249/546 (45%), Gaps = 98/546 (17%) Query: 11 AAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTLV 70 A+ PA+ +AS + GALP P A G T P T S R+P T Sbjct: 363 ASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLS-RTPTAT-- 419 Query: 71 TKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLVS 130 T + P V + PRLP P N T IQ N QLPPG VL++S +G L+++ Sbjct: 420 TSGIRATLTPTVLA-PRLPQPP------QNPTNIQ---NFQLPPGMVLVRSENGQLLMIP 469 Query: 131 PQ-----QTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIG 185 Q Q A+ + + RPA P + V+I TV + +I + VTP + Q+ Sbjct: 470 QQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIAR-QVTPTTIIKQVS 528 Query: 186 TTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLKAENSA 245 T P + +S V +V G T + +++ + P +SA Sbjct: 529 QAQTTVQPSATLQRSPGVQPQLVL---GGAAQTASLGTATAVQTGTPQRTVPGATTTSSA 585 Query: 246 AVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTR 305 A + +ENVKKCKNFL+ LIKLA SG QS E NVK+LV+ LLD KIEAE+FT Sbjct: 586 ATET------MENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEAEDFTS 639 Query: 306 KLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSP 365 +LY EL SSPQP+LVPFLK+S+ ALRQL P+S +FIQQ QQ + TT T+ Sbjct: 640 RLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQPPPP---TSQATTALTAV 696 Query: 366 VVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAATGGTT 425 V++++V + + + V+ A P +S+ T T Sbjct: 697 VLSSSVQRTAGKTAATVTSALQPPVLSL---------------------------TQPTQ 729 Query: 426 AGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAICLPSVK 485 G G PLV QP KP + P VT +T A+ P Sbjct: 730 VGVGKQGQPTPLVIQ----------QPPKP-----GALIRPPQVTLTQTPMVALRQP--- 771 Query: 486 PVVSSAGTTSDKPVIGTPVQIKL--AQPGPVLSQPAGIP----------QAVQVKQLVVQ 533 ++ ++ TP QI+L QP PV+ +PA +P QA ++ ++ Sbjct: 772 ---------HNRIMLTTPQQIQLNPLQPVPVV-KPAVLPGTKALSAVSAQAAAAQKNKLK 821 Query: 534 QPSGGN 539 +P GG+ Sbjct: 822 EPGGGS 827 >gi|91982772 mucin 17 [Homo sapiens] Length = 4493 Score = 82.0 bits (201), Expect = 2e-15 Identities = 157/676 (23%), Positives = 263/676 (38%), Gaps = 116/676 (17%) Query: 6 TEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVS--VCVEPTASQPLR 63 T P P + ++ G+ + A ++V S+ T +S V + AS Sbjct: 199 TTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPT 258 Query: 64 SPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNS 123 + G ++ AP ++ R+P ++ V + +T PA +P T S+S Sbjct: 259 TAEGPSLSNSAPSGGSTPLT---RMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSS 315 Query: 124 GPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQ 183 + T T E ++ +TS PA T+P ++S++ +++TPV Sbjct: 316 PTTAEGTSIPTSTYTEGSTPLTSTPA----------STMPVATSEM-STLSITPVDT--- 361 Query: 184 IGTTVVTTVPKPSSVQSVAVPTSVVTVTPGK---PLNT--VTTLKPSSLGASSTPSNEPN 238 +T+VTT +PSS+ + A TS++T T + PL V+T+ +S AS+T + + Sbjct: 362 --STLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVD 419 Query: 239 LKAENSAAVQINLSPTMLENVKKCKNFLA--MLIKLACSGSQSPEMGQNVKKLVEQLLDA 296 K + A + + SPT E+ + + + S +P L +D+ Sbjct: 420 SKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDS 479 Query: 297 KIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIAT 356 K + T E SSP V + S S+ S+ V ++ Sbjct: 480 KTQVTTST-----EASSSPPTAEVNSMPTST--------PSEGSTPLTSMSVSTMPVASS 526 Query: 357 CTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAG-------PVGAKAGV 409 +T++T+PV T+T ++ SE S S +T P S+ T P G PV + V Sbjct: 527 EASTLSTTPVDTSTPVTTSSEAS---SSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVV 583 Query: 410 VTLHSVGPT--------------AATGGTTA-GTGL--------------LQTSKPLV-T 439 + S T A++ TTA GT + + S LV + Sbjct: 584 SSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVAS 643 Query: 440 SVANTVTTVSLQPEKPVVSGTAVT--------LSLPAVTFGETSGAAICLPSVKPVVSS- 490 S A+T++T + PV + T T S+P T+ E S +P +V+S Sbjct: 644 SEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASS 703 Query: 491 -AGTTSDKPV-IGTPVQIKL-AQPGPVLSQPAGIPQA-------------VQVKQLVVQQ 534 A T S PV TPV A P + A +P + V L + Sbjct: 704 EASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSE 763 Query: 535 PSGGNEKQVTTISHSSTLTIQKCGQKT-----MPVNTIIPTSQFPPASILKQITLPGNKI 589 S + + T +H +T T C T MP++T P+ P +L I + + Sbjct: 764 ASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPIST--PSEGSP---LLTSIPVSITPV 818 Query: 590 LSLQASPTQKNRIKEN 605 S +AS + N Sbjct: 819 TSPEASTLSTTPVDSN 834 Score = 76.3 bits (186), Expect = 1e-13 Identities = 143/635 (22%), Positives = 229/635 (36%), Gaps = 107/635 (16%) Query: 2 PAGLTEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCV----EPT 57 P + A + PP A S + + G P+ T+ PVS + E + Sbjct: 2309 PFTTSTEASSPPPTAEGTSMPTSTSSEGNTPL------------TRMPVSTTMVASFETS 2356 Query: 58 ASQPLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTV 117 + T VT + + P + +P P T+ P + + Sbjct: 2357 TLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSV---PVSTMPVVSSE 2413 Query: 118 LIKSNSGPLMLVSPQQTVTRAE---TTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVA 174 ++ P+ +P T T A TT+ TS P P + T + ++P S++ ++ A Sbjct: 2414 ASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEA 2473 Query: 175 ----VTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVV----TVTPGKPLNTVTTLKPSS 226 TPV + TT P++ + + VP S T+ P++T P + Sbjct: 2474 GTLSTTPVDTSTPM-TTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEA 2532 Query: 227 LGASSTP--SNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQ 284 S+TP SN P + + ++ + T + + + + S P Sbjct: 2533 STLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLR---SMPVSTKPLASS 2589 Query: 285 NVKKLVEQLLDAKIEAEEFTRKLYVELKSSP---QPHLVPFLKKSVVALRQLLPNSQSFI 341 L +D I T E SSP + +P S V+ S + I Sbjct: 2590 EASTLSTTPVDTSIPVTTST-----ETSSSPTTAKDTSMPISTPSEVS------TSLTSI 2638 Query: 342 QQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAG 401 +S TT V T +VTT+ +S S + G++ P + + PL Sbjct: 2639 LVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTT--AEGSSMPTSTPGERSTPLTN 2696 Query: 402 -------------------PVGAKAGVVTLH--SVGPTAATG----------GTTAGTGL 430 PV V T S PT A G G+T T + Sbjct: 2697 ILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSI 2756 Query: 431 LQTSKPLVTSVANTVTTVSLQPEKPVVSG--------TAVTLSLPAVTFGETSGAAICLP 482 L ++ P+ +S A+TV+T ++ PV + TA S+P T ETS +P Sbjct: 2757 LVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMP 2816 Query: 483 -SVKPVVSS-AGTTSDKPV-IGTPVQIKL-AQPGPVLSQPAGIP--QAVQVKQLVVQQPS 536 + PV SS AGT S PV TPV A P ++ +P A + L+ P Sbjct: 2817 VNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIP- 2875 Query: 537 GGNEKQVTTISHSSTLTIQKCGQKTMPVNTIIPTS 571 T ++ S T+ T PV+T IP + Sbjct: 2876 ----VSTTPVASSEASTL-----STTPVDTSIPVT 2901 Score = 76.3 bits (186), Expect = 1e-13 Identities = 145/688 (21%), Positives = 247/688 (35%), Gaps = 119/688 (17%) Query: 6 TEPAGAAPPAAVSA--SGTVTMAPAGALPVRVES---TPVALGAVTKAPVSVCVEPTASQ 60 T P P SA S + T A ++P+ TP+ +V+ PV+ T S+ Sbjct: 2950 TTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSR 3009 Query: 61 PLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVL-- 118 + T VT S+ P + G +P P T+ + +P + L Sbjct: 3010 T-PADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLST 3068 Query: 119 --IKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQT-VKICTVPNSSSQLIKKVAV 175 + SNS + + T AE TS S + + P T V + T P +SS I ++ Sbjct: 3069 TPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSA-ISTLST 3127 Query: 176 TPVKKLAQI--------------GTTVVTTVPKPSSVQSVAVPTSVVTVTPGK------- 214 TPV + GT++ T+ P S +P S + V + Sbjct: 3128 TPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSAT 3187 Query: 215 PLNTVTTLKPSSLGASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAML----- 269 P++T T + S+ SST + ++ + L+ + N + ++L Sbjct: 3188 PVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPV 3247 Query: 270 -----IKLACSGSQSPEMGQNVKKLVEQ-------LLDAKIEAEEFTRKLYVELKSSPQP 317 + + S SP + L + L ++P Sbjct: 3248 DSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPAD 3307 Query: 318 HLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDM---------VIATCTTTVTTSPVVT 368 P S + + + S + S+ + V+++ +T++T+PV T Sbjct: 3308 TSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDT 3367 Query: 369 TTVSSSQSEKSI---IVSGATAPRTVSVQTLNPLAG-------------------PVGAK 406 +T ++ +E S+ G + P + + PLA PV + Sbjct: 3368 STPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSN 3427 Query: 407 AGVVTL--HSVGPTAATG----------GTTAGTGLLQTSKPLVTSVANTVTTVSLQPEK 454 V T S PT A G G+T + + ++ P+ +S A+T++T + Sbjct: 3428 TLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTST 3487 Query: 455 PVVSG--------TAVTLSLPAVTFGETSGAAICLP-SVKPVVSS-AGTTSDKPVIGTPV 504 PV + TA S+P T GE S +P S PV SS A T S PV Sbjct: 3488 PVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTF 3547 Query: 505 QIKLAQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCG------ 558 SQ + P +QV + + PS G+ T + S+ +T + Sbjct: 3548 VTS-------SSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPS 3600 Query: 559 -QKTMPVNTIIPTSQFPPASILKQITLP 585 ++ PV T ++ P + ITLP Sbjct: 3601 VDRSTPVTTSTQSNSTPTPP--EVITLP 3626 Score = 73.9 bits (180), Expect = 6e-13 Identities = 143/602 (23%), Positives = 231/602 (38%), Gaps = 98/602 (16%) Query: 6 TEPAGAAPPAAVS--ASGTVTMAPAGALPVRVES---TPVALGAVTKAPV-SVCVEPTAS 59 T P + P S AS + T A ++P S TP+A V+ PV S V ++ Sbjct: 3362 TTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLST 3421 Query: 60 QPLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPP-GTVL 118 P+ S TLVT S+ P ++ G LP +TT + L + P T Sbjct: 3422 TPVDS--NTLVTTSTEASSSPTIAEGTSLPT----------STTSEGSTPLSIMPLSTTP 3469 Query: 119 IKSNSGPLMLVSPQQTVT---------RAETTSNITSRPAVPANPQTVKICTVPNSSSQL 169 + S+ + +P T T + TT+ +TS P A + + +P S++ + Sbjct: 3470 VASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPV 3529 Query: 170 IKKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGA 229 A T + T VT+ + SS + T++ TP + +++TT+ SS Sbjct: 3530 ASSEAST-LSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYV 3588 Query: 230 SSTPSNEPNLKAEN-----SAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQ 284 +S+ ++ P+ + + + + Q N +PT E +I L S Sbjct: 3589 TSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPE-----------VITLPMS--------- 3628 Query: 285 NVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQC 344 ++ L + T + P P + + V+ + P Sbjct: 3629 TPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEG------- 3681 Query: 345 VQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVG 404 T + +T +TT PV TT V+SS+ G+T T SV T P+ Sbjct: 3682 --TTMPIWTPSEGSTPLTTMPVSTTRVTSSE--------GSTL-STPSVVTSTPVTTSTE 3730 Query: 405 AKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTL 464 A + TL S TT + L T++ + T V+ PE S +V Sbjct: 3731 AISSSATLDS---------TTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYT 3781 Query: 465 SLPAVTFGETSGAAICLPSVKPVVSSAGTTSDK-----PVIGTPVQIKLAQPGPVLSQPA 519 S+ T E S + L + S TTS++ V+ +P+ + LS P Sbjct: 3782 SMSMTTASEGSSSPTTLEGTTTMPMS--TTSERSTLLTTVLISPISVMSPSEASTLSTPP 3839 Query: 520 G---IPQAVQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKTMPVNTIIPTSQFPPA 576 G P K P+ +VTTI S T + + T+ V+T +PTS FP A Sbjct: 3840 GDTSTPLLTSTKAGSFSIPA-----EVTTIRISIT-SERSTPLTTLLVSTTLPTS-FPGA 3892 Query: 577 SI 578 SI Sbjct: 3893 SI 3894 Score = 72.8 bits (177), Expect = 1e-12 Identities = 146/657 (22%), Positives = 242/657 (36%), Gaps = 112/657 (17%) Query: 6 TEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCV----EPTASQP 61 T ++PP + T P+ STP+ T+ PVS + E + Sbjct: 1016 TSTEASSPPPTAEGTSMPTSTPSEG------STPL-----TRMPVSTTMVASSETSTLST 1064 Query: 62 LRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKS 121 + T VT + S+ + G +P P T+ P + +L + Sbjct: 1065 TPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSV---PVSTRLVVSSEASTL 1121 Query: 122 NSGPLMLVSPQQTVTRAE---TTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVA---- 174 ++ P+ P T T A TT+ TS P P + T + ++P S++ ++ A Sbjct: 1122 STTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLS 1181 Query: 175 VTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLK----PSSLGAS 230 TPV Q+ T+ + P P+ A TS+ T TPG+ +T++ P + + Sbjct: 1182 TTPVDSKTQVATSTEASSPPPT-----AEVTSMPTSTPGERSTPLTSMPVRHTPVASSEA 1236 Query: 231 STPSNEP-NLKAENSAAVQINLSPTMLENVKKCKNF------LAMLIKLACSGSQSPEMG 283 ST S P + + + + + SPT E + L I ++ + SPE Sbjct: 1237 STLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEAS 1296 Query: 284 QNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQ-------------PHLVPFLKKSVVAL 330 + V+ E + E S P P + S +++ Sbjct: 1297 TLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISI 1356 Query: 331 RQLLPNSQSF-----IQQCVQQTSSDMVI------ATCTTTVTTSPVVTTTVSSSQ-SEK 378 P S + C T+S+ + TT +T+ PV TT V SS+ S Sbjct: 1357 LSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTL 1416 Query: 379 SIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLV 438 S + P T S + + P A+ G+ S+ + + G T + ++ P+ Sbjct: 1417 SATPVDTSTPGTTSAEATS---SPTTAE-GI----SIPTSTPSEGKTPLKSIPVSNTPVA 1468 Query: 439 TSVANTVTTVSLQPEKPVVSGTAVT--------LSLPAVTFGETSGAAICLP-------- 482 S A+T++T + PVV+ TAV+ S+ T E S A +P Sbjct: 1469 NSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVAS 1528 Query: 483 ------SVKPVVSSAGTT-----SDKPVI--GTPVQIKLAQPG--PVLSQPAGIPQAVQV 527 S P V+S T S P GT +Q G P+ S P V Sbjct: 1529 SEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSS 1588 Query: 528 KQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKTM-------PVNTIIPTSQFPPAS 577 + + ++ QVT + +S+ T + T+ P+ T IP S P AS Sbjct: 1589 EANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVAS 1645 Score = 72.4 bits (176), Expect = 2e-12 Identities = 148/671 (22%), Positives = 244/671 (36%), Gaps = 130/671 (19%) Query: 5 LTEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRS 64 LT P A SA T++ P STPV T+A S S P + Sbjct: 1692 LTSITVRTTPVASSAISTLSTTPVD------NSTPVTTS--TEARSSPTTSEGTSMPNST 1743 Query: 65 PV-GTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNS 123 P GT PVS P +SS + + P TT+ + ++ GT + Sbjct: 1744 PSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSI----- 1798 Query: 124 GPLMLVSPQQTVTRAETTSNITSRPA---VPANPQTVKICTVP-NSSSQLIKKVAVTPVK 179 T T +E + +TS P + AN + + T P +S+S ++ AV+ Sbjct: 1799 ---------PTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSP 1849 Query: 180 KLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNL 239 A+ GT++ T+ P S ++P S TV + NT++T + +STP Sbjct: 1850 TPAE-GTSIATSTPSEGSTALTSIPVSTTTVASSE-TNTLST----TPAVTSTPV----- 1898 Query: 240 KAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIE 299 + Q++ SPT + + + +P G+ + Sbjct: 1899 ----TTYAQVSSSPTTADG--------------SSMPTSTPREGRPPLTSIPVSTTTVAS 1940 Query: 300 AEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPN---SQSFIQQCVQQTSSDMVIAT 356 +E T + +P A +P S+ S+ +V+++ Sbjct: 1941 SEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSS 2000 Query: 357 CTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQT------LNPLAG--------- 401 +T++T+PV T+T +++ +E S S T S+QT PLAG Sbjct: 2001 EASTLSTTPVDTSTPATTSTEGS---SSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVV 2057 Query: 402 ----------PVGAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSV---------- 441 PV +K V +A G++ PL+TS+ Sbjct: 2058 SSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASP 2117 Query: 442 -ANTVTTVSLQPEKPVVSGTAVT--------LSLPAVTFGETSGAAICLPSVKPVVSSA- 491 A+T++T + PV++ T V+ S+ T+ + +P VV+S+ Sbjct: 2118 EASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSA 2177 Query: 492 -GTTSDKPV-IGTPVQIKL-AQPGPVLSQPAGIPQA-------------VQVKQLVVQQP 535 T S PV TPV A+ P S+ +P + V +V + Sbjct: 2178 ISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEA 2237 Query: 536 SGGNEKQVTTISHSSTLTIQKCGQKTMPVNTIIPTSQF-----PPASILKQITLPGN-KI 589 S + V T + +T T + T T IPTS P SI TL N ++ Sbjct: 2238 STLSATPVDTSTPVTTST-EATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEV 2296 Query: 590 LSLQASPTQKN 600 +L +P N Sbjct: 2297 STLSTTPVDSN 2307 Score = 71.6 bits (174), Expect = 3e-12 Identities = 136/622 (21%), Positives = 234/622 (37%), Gaps = 85/622 (13%) Query: 6 TEPAGAAPPAAVSASGTVTMA--PAGALPV------RVESTPVALGAVTKAPVSVCVEPT 57 T G + P + + GT +A P PV + +TPV PT Sbjct: 2439 TTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPT 2498 Query: 58 ASQPLRSPVGT------LVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQ 111 ++ + P+ T L+T + PVS P S + V +P T+ + ++ Sbjct: 2499 TAEDIVVPISTASEGSTLLTSI-PVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSAT 2557 Query: 112 LPPGTVLIKSN----SGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSS 167 GT + S S PL + + S +++ P + P T T SSS Sbjct: 2558 SAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTET---SSS 2614 Query: 168 QLIKKVAVTPVKKLAQIGTTV----VTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLK 223 K P+ +++ T++ V+T+P SS S T V T T +T T+ Sbjct: 2615 PTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTL-VTTSTGTSSS 2673 Query: 224 PSSLGASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMG 283 P++ SS P++ P ++ + I +S T+L N + A + S +P Sbjct: 2674 PTTAEGSSMPTSTPGERS--TPLTNILVSTTLLANSE------------ASTLSTTPVDT 2719 Query: 284 QNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQ 343 + + AE + ++ S+P P L +V+ + + S + Sbjct: 2720 STPVTTSAEASSSPTTAEGTSMRI-----STPSDGSTP-LTSILVSTLPVASSEASTVST 2773 Query: 344 CVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKS------------IIVSGATAPRTV 391 TS + +T ++ T+ VT+ +S+ SE S + S A T Sbjct: 2774 TAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTT 2833 Query: 392 SVQTLNPLAGPVGAKAGVVTLHS--VGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVS 449 V T P+ A + T V + A+ G+T T + ++ P+ +S A+T++T Sbjct: 2834 PVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTP 2893 Query: 450 LQPEKPVVSG--------TAVTLSLPAVTFGETSG--AAICLPSVKPVVSSAGTTSDKPV 499 + PV + TA S+P T E S +I + +V S A T S PV Sbjct: 2894 VDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPV 2953 Query: 500 -IGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCG 558 TPV ++ + P + + + P G + T ST+ + Sbjct: 2954 DTRTPVTTS--------AEASSSPTTAEGTSMPISTP--GERRTPLTSMSVSTMPVASSE 3003 Query: 559 QKTM---PVNTIIPTSQFPPAS 577 T+ P +T P + AS Sbjct: 3004 ASTLSRTPADTSTPVTTSTEAS 3025 Score = 71.2 bits (173), Expect = 4e-12 Identities = 139/677 (20%), Positives = 245/677 (36%), Gaps = 100/677 (14%) Query: 2 PAGLTEPAGAAPPAA---VSASG-TVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPT 57 P+ T P P + VS+ G T++ P + ST + A + P+ Sbjct: 2039 PSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPS 2098 Query: 58 ASQPLRSPVGTLVTKVAP-----VSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQ- 111 PL + + T VA +S P S+ P + + ++ + P T + Sbjct: 2099 EGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSD 2158 Query: 112 -------LPPGTVLIKSNSGPLMLVSPQQTVT-------------RAETTSNITSRPAVP 151 +P T ++ S++ + +P T T +E TS TS P+ Sbjct: 2159 RRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEG 2218 Query: 152 ANPQT-VKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVV-- 208 + P T + + T+P +S+ ++ TPV + T+ T P++ + ++PTS + Sbjct: 2219 STPFTSMPVSTMPVVTSEA-STLSATPVDTSTPVTTSTEAT-SSPTTAEGTSIPTSTLSE 2276 Query: 209 ------------TVTPGKPLNTVTTLK-------PSSLGASSTPSNEPNLKAENSAAVQI 249 T+ ++T++T +S ASS P S + + Sbjct: 2277 GTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEG 2336 Query: 250 NLSPTMLE-NVKKCKNFLAMLIKLACSGSQSP-----EMGQNVKKLVEQLLDAKIEAEEF 303 N T + + +F + + + +P + G + + + +E Sbjct: 2337 NTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGS 2396 Query: 304 TRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTT 363 T V + + P + S + P S + SS A T+ T+ Sbjct: 2397 TPLTSVPVSTMP-------VVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTS 2449 Query: 364 SPVVTTTVSSSQ--SEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHS--VGPTA 419 P TT +S S ++ S A T V T P+ A + T V + Sbjct: 2450 PPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPIST 2509 Query: 420 ATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVT--------LSLPAVTF 471 A+ G+T T + ++ P+ + A+T++T + PVV+ T ++ S+P T+ Sbjct: 2510 ASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTY 2569 Query: 472 GETSGAAICLP-SVKPVVSSAGTTSDKPVIGTPVQIKLA---QPGPV----LSQPAGIPQ 523 E S +P S KP+ SS +T + T + + + P S P P Sbjct: 2570 SEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPS 2629 Query: 524 AVQVKQ---LVVQQPSGGNEKQV--TTISHSSTLTIQKCGQKTMPV---NTIIPTS---- 571 V LV P +E TT + TL G + P + +PTS Sbjct: 2630 EVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGE 2689 Query: 572 -QFPPASILKQITLPGN 587 P +IL TL N Sbjct: 2690 RSTPLTNILVSTTLLAN 2706 Score = 66.6 bits (161), Expect = 9e-11 Identities = 128/611 (20%), Positives = 212/611 (34%), Gaps = 75/611 (12%) Query: 6 TEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSP 65 T G P ++ + T+ + A ++ + +TPV C PT S+ P Sbjct: 1331 TYSEGRTPLTSIPVNTTLVASSAISI---LSTTPVDNSTPVTTSTEACSSPTTSEGTSMP 1387 Query: 66 -----VGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIK 120 GT PVS P VSS + V P TT+ + ++ G + Sbjct: 1388 NSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISI-- 1445 Query: 121 SNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVP-NSSSQLIKKVAVTPVK 179 P S +T ++ SN AN + + T P +S+S ++ AV+ Sbjct: 1446 ----PTSTPSEGKTPLKSIPVSNTPV-----ANSEASTLSTTPVDSNSPVVTSTAVSSSP 1496 Query: 180 KLAQIGTTVVTTVPKPSSVQSVAVPTSVVTV----------TPGKPLNTVTTLKPSSLGA 229 A+ GT++ + P S ++P S TV TP VTT +S Sbjct: 1497 TPAE-GTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSP 1555 Query: 230 SSTPSNEPNLKAENSAAVQINLSP--TMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVK 287 ++ + + + P TML + I + S E + Sbjct: 1556 TTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTT 1615 Query: 288 KLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQ 347 + I L + S P P + S ++ + NS V Sbjct: 1616 AEGSSMT---ISTPSEGSPLLTSIPVSTTPVASP--EASTLSTTPVDSNSPVITSTEVSS 1670 Query: 348 T---SSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVG 404 + + + T T T +P+ + TV ++ S I + +T P V P+ Sbjct: 1671 SPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTP----VDNSTPVTTSTE 1726 Query: 405 AKAGVVTLH--SVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAV 462 A++ T S+ + + GTT T + ++ P+++S A+T++ + PV + T Sbjct: 1727 ARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEA 1786 Query: 463 T--------LSLPAVTFGETSGAAICLPSVKPVV--SSAGTTSDKPVIGTPVQIKLAQPG 512 T S+P T E P +V S A T S PV Sbjct: 1787 TSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSN---------S 1837 Query: 513 PVLSQPA--GIPQAVQVKQLVVQQPSGGNEK------QVTTISHSSTLTIQKCGQKT-MP 563 PV++ A P + + PS G+ TT++ S T T+ T P Sbjct: 1838 PVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTP 1897 Query: 564 VNTIIPTSQFP 574 V T S P Sbjct: 1898 VTTYAQVSSSP 1908 Score = 66.6 bits (161), Expect = 9e-11 Identities = 137/606 (22%), Positives = 224/606 (36%), Gaps = 74/606 (12%) Query: 1 MPAGLTEPAGAAPPAAVSASGTVTMAPAGALPVRVEST--PVALGAVTKAPVS---VCVE 55 +P +E + + A ++ T A + P E T P + + T P++ V Sbjct: 2761 LPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHT 2820 Query: 56 PTASQPLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPG 115 P AS + T V PV+ K SS P +V + + + + +P Sbjct: 2821 PVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTS---IPVS 2877 Query: 116 TVLIKSNSGPLMLVSPQQTV-------------TRAETTSNITSRPAVPANPQT-VKICT 161 T + S+ + +P T T AE TS S P+ + P T + + T Sbjct: 2878 TTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVST 2937 Query: 162 VPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTT 221 VP + S+ ++ TPV T VTT + SS + A TS+ TPG+ +T+ Sbjct: 2938 VPVAGSEA-STLSTTPVDT-----RTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTS 2991 Query: 222 LKPSSLG-ASSTPSNEPNLKAENSAAV----QINLSPTMLEN----VKKCKNFLAMLIKL 272 + S++ ASS S A+ S V + + SPT E + L + Sbjct: 2992 MSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSI 3051 Query: 273 ACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQ 332 S +P L +D+ T E+ SSP P + S Sbjct: 3052 PV--STTPVAIPEASTLSTTPVDSNSPVVTST-----EVSSSPTPAEGTSMPISTY---- 3100 Query: 333 LLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVS 392 S+ S+ V ++ +T++T+PV T+T ++ +E S T S Sbjct: 3101 ----SEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAH---SSPTTSEGTS 3153 Query: 393 VQTLNPLAGPVGAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQP 452 + T P G V+ V ++ +T + TS P+ TS T +T + Sbjct: 3154 MPTSTPSEGSTPLTYMPVSTMLV---VSSEDSTLSATPVDTSTPVTTSTEATSSTTA--- 3207 Query: 453 EKPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPV-IGTPVQIKL-AQ 510 GT++ S P+ G T ++ + + S A S PV TP+ A Sbjct: 3208 -----EGTSIPTSTPSE--GMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEAS 3260 Query: 511 PGPVLSQPAGIPQAVQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKT-MPVNTIIP 569 P ++ +P + + P TT++ S T T+ T PV T Sbjct: 3261 SSPPTAEGTSMPTSTPSEG---STPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQ 3317 Query: 570 TSQFPP 575 S PP Sbjct: 3318 ASSSPP 3323 Score = 66.2 bits (160), Expect = 1e-10 Identities = 136/637 (21%), Positives = 225/637 (35%), Gaps = 100/637 (15%) Query: 8 PAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVS--VCVEPTASQPLRSP 65 P + P S T + A + + +T PVS + AS +P Sbjct: 948 PVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTP 1007 Query: 66 V--GTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNS 123 V T +T S+PP + G +P P T ++P T ++ S+ Sbjct: 1008 VDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLT---------RMPVSTTMVASSE 1058 Query: 124 GPLMLVSPQQTVT---------RAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVA 174 + +P T T + TT++ TS P + + + +VP S+ ++ A Sbjct: 1059 TSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEA 1118 Query: 175 VTPVKKLAQIGTTV-VTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTP 233 T + T++ VTT + SS + A TS+ T P + + ++ S+ S+ Sbjct: 1119 ST--LSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSE 1176 Query: 234 SNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQL 293 +N LS T +++ + + + S P + Sbjct: 1177 AN--------------TLSTTPVDSKTQ--------VATSTEASSPPPTAEVTS------ 1208 Query: 294 LDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMV 353 + E T L S P H + VA + S S + T+S Sbjct: 1209 MPTSTPGERST-----PLTSMPVRH-------TPVASSEASTLSTSPVDTSTPVTTSAET 1256 Query: 354 IATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLH 413 ++ TT TS +TT S SI VS T + TL L PV K VVT + Sbjct: 1257 SSSPTTAEGTSLPTSTTSEGSTLLTSIPVS-TTLVTSPEASTL--LTTPVDTKGPVVTSN 1313 Query: 414 SV--GPTAATGGTTAGTGLLQTSKPLVTSVANTV----TTVSLQPEKPVVSGTAVTLSLP 467 V PT A G + + + PL + NT + +S+ PV + T VT S Sbjct: 1314 EVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTE 1373 Query: 468 AVTFGETSGAAICLPSVKPVVSSAGTT--SDKPVIGTPV-----------QIKLAQPGPV 514 A + T+ +P+ P S GTT + PV TPV + + PG Sbjct: 1374 ACS-SPTTSEGTSMPNSNP---SEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTT 1429 Query: 515 LSQPAGIPQAVQVKQLVVQQPSGGNEK-QVTTISHSSTLTIQKCGQKTMPV--------N 565 ++ P + + PS G + +S++ + T PV + Sbjct: 1430 SAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTS 1489 Query: 566 TIIPTSQFPPASILKQITLPGNKILSLQASPTQKNRI 602 T + +S P I+ P +L + P + Sbjct: 1490 TAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTV 1526 Score = 65.9 bits (159), Expect = 2e-10 Identities = 136/633 (21%), Positives = 228/633 (36%), Gaps = 111/633 (17%) Query: 6 TEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSP 65 T ++PP + T P STP+ V PV+ T S SP Sbjct: 1193 TSTEASSPPPTAEVTSMPTSTPGE------RSTPLTSMPVRHTPVASSEASTLST---SP 1243 Query: 66 VGTL--VTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNS 123 V T VT A S+ P + G LP +TT+ +P T L+ S Sbjct: 1244 VDTSTPVTTSAETSSSPTTAEGTSLPT---------STTSEGSTLLTSIPVSTTLVTSPE 1294 Query: 124 GPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNS---------SSQLIKKVA 174 +L +P T TSN S PA ++ T ++ L+ A Sbjct: 1295 ASTLLTTPVDTKGPV-VTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSA 1353 Query: 175 VTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPS-----SLGA 229 ++ + +T VTT + S + + TS+ P + +T++ S S A Sbjct: 1354 ISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEA 1413 Query: 230 SSTPSNEPNLKAENSAAVQINLSPTMLENV-------KKCKNFLAMLIKLACSGSQSPEM 282 S+ + + + + + SPT E + + K L + S +P Sbjct: 1414 STLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSI-----PVSNTPVA 1468 Query: 283 GQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQ 342 L +D+ T + SSP P + + +A+ S + Sbjct: 1469 NSEASTLSTTPVDSNSPVVTST-----AVSSSPTP-----AEGTSIAISTPSEGSTALTS 1518 Query: 343 QCVQQT---SSDMVIATCTTTVTTSPVVT--------TTVSSSQSEKSIIVSGATAPRTV 391 V T SS++ + T VT++PV T TT + + S G+T ++ Sbjct: 1519 IPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSL 1578 Query: 392 SVQTL-------NPLA-GPVGAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSV-- 441 V T+ N L+ P+ +K V + G++ PL+TS+ Sbjct: 1579 PVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPV 1638 Query: 442 ---------ANTVTTVSLQPEKPVVSGTAVT--------LSLPAVTF--GETSGAAICLP 482 A+T++T + PV++ T V+ S+P T+ G T +I + Sbjct: 1639 STTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVR 1698 Query: 483 SVKPVVSSAGTTSDKPV-IGTPVQIKL-AQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNE 540 + S+ T S PV TPV A+ P S+ +P + PS G Sbjct: 1699 TTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNST---------PSEGT- 1748 Query: 541 KQVTTISHSST--LTIQKCGQKTMPVNTIIPTS 571 +T+I S+T L+ + P++T P + Sbjct: 1749 TPLTSIPVSTTPVLSSEASTLSATPIDTSTPVT 1781 Score = 65.5 bits (158), Expect = 2e-10 Identities = 145/678 (21%), Positives = 247/678 (36%), Gaps = 130/678 (19%) Query: 2 PAGLTEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQP 61 P + A ++PP A S + G+ P+ S PV+ V + S A Sbjct: 3252 PLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLT--SMPVSTTTVASSETSTLSTTPAD-- 3307 Query: 62 LRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKS 121 T VT + S+ P ++ G +P P T + F T ++ S Sbjct: 3308 ----TSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTP-LTNMSFST-------TPVVSS 3355 Query: 122 NSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSS-SQLIKKVAVTPVKK 180 + L + T +T++ +T+ +P T + ++P SS S+ +A PV Sbjct: 3356 EASTL-------STTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVST 3408 Query: 181 LAQIGT-------------TVVTTVPKPSSVQSVAVPTSVVTVTPGK--------PLNTV 219 + + T+VTT + SS ++A TS+ T T + PL+T Sbjct: 3409 TPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTT 3468 Query: 220 TTLKPSSLGASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQS 279 + S+TP + +S N SPT E +M A GS + Sbjct: 3469 PVASSEASTLSTTPVDTSTPVTTSSPT---NSSPTTAE-------VTSMPTSTAGEGS-T 3517 Query: 280 PEMGQNVKKL------VEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQL 333 P V L +++ F + SS Q P V +R Sbjct: 3518 PLTNMPVSTTPVASSEASTLSTTPVDSNTF-------VTSSSQASSSP-ATLQVTTMRMS 3569 Query: 334 LPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSV 393 P+ S ++ TT + +S VT++ +S+ S S+ S T S Sbjct: 3570 TPSEGS---------------SSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSN 3614 Query: 394 QTLNP---LAGPVGAKAGVVTLHSVGPTAATGGT-----TAGTGLLQTSKPLVTSVANTV 445 T P + P+ + V T ++ P + T T TA T + TS P++TS V Sbjct: 3615 STPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITS--TQV 3672 Query: 446 TTVSLQPEKPVV------SGTAVTLSLPAVTFGETS--GAAICLPSV----------KPV 487 ++ + PE + G+ ++P T TS G+ + PSV + + Sbjct: 3673 SSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAI 3732 Query: 488 VSSAGTTSDKPVIGTPVQIK------LAQPGPVLSQP-AGIPQAVQVKQLVVQQPSGGNE 540 SSA S + P++I L PV P + P V + + Sbjct: 3733 SSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGS 3792 Query: 541 KQVTTISHSSTLTIQKCGQKTMPVNTII--PTSQFPPASILKQITLPGNKILSLQAS--- 595 TT+ ++T+ + +++ + T++ P S P+ T PG+ L S Sbjct: 3793 SSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKA 3852 Query: 596 -----PTQKNRIKENVTS 608 P + I+ ++TS Sbjct: 3853 GSFSIPAEVTTIRISITS 3870 Score = 63.2 bits (152), Expect = 1e-09 Identities = 127/547 (23%), Positives = 200/547 (36%), Gaps = 113/547 (20%) Query: 2 PAGLTEPAGAAPPAAVSASGTVTMAPAGALPVR---VESTPVA---LGAVTKAPVSVCVE 55 P + P ++P A S + A G+ P+ V +TPVA ++ PV Sbjct: 3488 PVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTF 3547 Query: 56 PTASQPLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPG 115 T+S S TL +S P + SS V + +T P+ + P Sbjct: 3548 VTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPV 3607 Query: 116 TVLIKSNSGPL---MLVSPQQTVTRAET--------TSNITSRPA-----VPANPQTVKI 159 T +SNS P ++ P T + T T+++T A +P + T I Sbjct: 3608 TTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVI 3667 Query: 160 CTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVP---------------KPSSVQSVAVP 204 + SSS + + P+ ++ G+T +TT+P PS V S V Sbjct: 3668 TSTQVSSSPVTPEGTTMPIWTPSE-GSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVT 3726 Query: 205 TSVVTVTPGKPLNTVTT-----LKPSSLGASSTPSNEPNLKAENSAAVQINLSPTMLENV 259 TS ++ L++ T ++ S+LG + S P + S+ I P++ Sbjct: 3727 TSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSI---PSV---- 3779 Query: 260 KKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHL 319 + +M + A GS SP E T + + S L Sbjct: 3780 -----YTSMSMTTASEGSSSPT------------------TLEGTTTMPMSTTSERSTLL 3816 Query: 320 VPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKS 379 L + + + P+ S + TS+ ++ +T + + VTT S SE+S Sbjct: 3817 TTVL---ISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERS 3873 Query: 380 IIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVT 439 T T+ V T TL PT+ G + A T L TS Sbjct: 3874 ------TPLTTLLVST---------------TL----PTSFPGASIASTPPLDTSTTFTP 3908 Query: 440 SVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGTT--SDK 497 S T + P PV A T+S+ +T G T G I +PS PV SS + Sbjct: 3909 S-----TDTASTPTIPV----ATTISVSVITEGSTPGTTIFIPST-PVTSSTADVFPATT 3958 Query: 498 PVIGTPV 504 + TPV Sbjct: 3959 GAVSTPV 3965 Score = 62.8 bits (151), Expect = 1e-09 Identities = 137/615 (22%), Positives = 217/615 (35%), Gaps = 110/615 (17%) Query: 6 TEPAGAAPPAAVS--ASGTVTMAPAGALPVRVES---TPVA-LGAVTKAPVSVCVEPTAS 59 T P + P S AS + T ++P S TP+ + T+ VS T++ Sbjct: 533 TTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTST 592 Query: 60 QPLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQI----VAVKAPNTTTIQFPANLQLPPG 115 P S T VT + S+ + G +P + + + +T ++ Sbjct: 593 TPADS--NTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLS 650 Query: 116 TVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAV 175 T + SN+ + T AE TS TS + P T +S ++ Sbjct: 651 TTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLST 710 Query: 176 TPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSL----GASS 231 TPV +T VTT + SS + A S+ T TP + +T++ S +S Sbjct: 711 TPVDT-----STPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEAS 765 Query: 232 TPSNEP-NLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQ---------SPE 281 T S P + + + + + SPT E +M I GS +P Sbjct: 766 TLSTTPLDTSTHITTSTEASCSPTTTEGT-------SMPISTPSEGSPLLTSIPVSITPV 818 Query: 282 MGQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFI 341 L +D+ T E+ SSP P A +P S Sbjct: 819 TSPEASTLSTTPVDSNSPVTTST-----EVSSSPTP-----------AEGTSMPTS---- 858 Query: 342 QQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAG 401 + T +T+ PV TT V++S I + +T P V T P+ Sbjct: 859 -----------TYSEGRTPLTSMPVSTTLVATSA-----ISTLSTTP----VDTSTPVTN 898 Query: 402 PVGAKAGVVTLHSVG-PTAATG-GTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSG 459 A++ T PT+ G G+T T + ++ P+V+S A T++ + PV + Sbjct: 899 STEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTS 958 Query: 460 TAVT--------LSLPAVTFGETSGAAICLPSVKPVV--SSAGTTSDKPV-IGTPVQIKL 508 T T S+P T E + P +V S A T S PV TP+ Sbjct: 959 TEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTST 1018 Query: 509 AQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNEK------QVTTISHSSTLTIQKCGQKTM 562 P P + + PS G+ T ++ S T T+ T Sbjct: 1019 EASSP--------PPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTL-----STT 1065 Query: 563 PVNTIIPTSQFPPAS 577 P +T P + + AS Sbjct: 1066 PADTSTPVTTYSQAS 1080 Score = 62.4 bits (150), Expect = 2e-09 Identities = 137/616 (22%), Positives = 227/616 (36%), Gaps = 84/616 (13%) Query: 6 TEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRS- 64 T P + P S + + + PA + + + A+T PVS AS + S Sbjct: 1477 TTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTT--VASSEINSL 1534 Query: 65 -----PVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLI 119 T VT + S+ P + G + P T+ LP T+L+ Sbjct: 1535 STTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTS---------LPVSTMLV 1585 Query: 120 KSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAV--TP 177 S+ + +P + T+ ++ +S + T+ + P+ S L+ + V TP Sbjct: 1586 VSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTI---STPSEGSPLLTSIPVSTTP 1642 Query: 178 VK--KLAQIGTT-------VVTTVP---KPSSVQSVAVPTSVVTVTPGK-PLNTVTT-LK 223 V + + + TT V+T+ P+ + ++PTS T T G+ PL ++T Sbjct: 1643 VASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTS--TYTEGRTPLTSITVRTT 1700 Query: 224 PSSLGASSTPSNEPNLKAENSAAV----QINLSPTMLENVKKCKNFLAMLIKLACS--GS 277 P + A ST S P +NS V + SPT E + + S S Sbjct: 1701 PVASSAISTLSTTP---VDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVS 1757 Query: 278 QSPEMGQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNS 337 +P + L +D T E SSP + S ++ + P + Sbjct: 1758 TTPVLSSEASTLSATPIDTSTPVTTST-----EATSSPTTAEGTSIPTSTLS-EGMTPLT 1811 Query: 338 QSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEK----SIIVS----GATAPR 389 + + + S ++T T + SPVVT+T SS SI S G+TA Sbjct: 1812 STPVSHTLVANSEASTLST-TPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALT 1870 Query: 390 TVSVQTL-------NPLAGPVGAKAGVVTLH---SVGPTAATGGTTAGTGLLQTSKPLVT 439 ++ V T N L+ + VT + S PT A G++ T + +P +T Sbjct: 1871 SIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTA-DGSSMPTSTPREGRPPLT 1929 Query: 440 SVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPV 499 S+ + TTV+ E +S T P T+ + S + + + A + P+ Sbjct: 1930 SIPVSTTTVA-SSEINTLSTTLADTRTPVTTYSQASSSPTTADGTS-MPTPAYSEGSTPL 1987 Query: 500 IGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQ 559 P+ L V+S A V S TT +S T + Sbjct: 1988 TSMPLSTTL-----VVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSER 2042 Query: 560 KT----MPVNTIIPTS 571 T MPV+T + S Sbjct: 2043 TTPLAGMPVSTTLVVS 2058 Score = 62.0 bits (149), Expect = 2e-09 Identities = 119/578 (20%), Positives = 208/578 (35%), Gaps = 68/578 (11%) Query: 15 AAVSASGT---VTMAPAGALPVR---VESTPVA---LGAVTKAPVSVCVEPTASQPLRSP 65 +A SA GT + G+ P+R V + P+A ++ PV + T S S Sbjct: 2555 SATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSS 2614 Query: 66 VGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQF-PANLQLPPGTVLIKSNSG 124 T P+S P +VS+ + V + +T+ P + + T S+S Sbjct: 2615 PTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSP 2674 Query: 125 PLMLVSPQQTVTRAETTS---NITSRPAVPANPQTVKICTVPNSSSQLIKKVA------- 174 S T T E ++ NI + AN + + T P +S + A Sbjct: 2675 TTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPT 2734 Query: 175 ---------VTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPS 225 TP + + +V+T+P SS S T+V T P +T + P+ Sbjct: 2735 TAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIP-VTTSTEASSSPT 2793 Query: 226 SLGASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNF---LAMLIKLACSGSQSPEM 282 + +S P++ P+ + ++ +N +P + + + S SP Sbjct: 2794 TAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTT 2853 Query: 283 GQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQ 342 + + ++ +E T + + ++P VA + S + + Sbjct: 2854 AEGI------VVPISTASEGSTLLTSIPVSTTP------------VASSEASTLSTTPVD 2895 Query: 343 QCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIV-------SGATAPRTVSVQT 395 + T+S ++ TT TS ++T S SI+V S A+ T V T Sbjct: 2896 TSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDT 2955 Query: 396 LNPLAGPVGAKAGVVTLHSVGPTAATGG--TTAGTGLLQTSKPLVTSVANTVTTVSLQPE 453 P+ A + T +T G T T + ++ P+ +S A+T++ Sbjct: 2956 RTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTS 3015 Query: 454 KPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGP 513 PV + T + S T E +G I PS + + PV TPV I A Sbjct: 3016 TPVTTSTEASSS---PTTAEGTGIPISTPS-----EGSTPLTSIPVSTTPVAIPEASTLS 3067 Query: 514 VLSQPAGIPQAVQVKQLVVQQPSGGNEKQVTTISHSST 551 + P + P+ G ++T S ST Sbjct: 3068 TTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGST 3105 Score = 60.1 bits (144), Expect = 9e-09 Identities = 143/679 (21%), Positives = 241/679 (35%), Gaps = 137/679 (20%) Query: 18 SASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVC--VEPTASQPLRSPV--GTLVTKV 73 S S T T + + E +P+ +T PVS+ P AS +PV + VT Sbjct: 785 SCSPTTTEGTSMPISTPSEGSPL----LTSIPVSITPVTSPEASTLSTTPVDSNSPVTTS 840 Query: 74 APVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLVSPQQ 133 VS+ P + G +P + P T+ +P T L+ +++ + +P Sbjct: 841 TEVSSSPTPAEGTSMPTSTYSEGRTPLTS---------MPVSTTLVATSAISTLSTTP-- 889 Query: 134 TVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVP 193 +T++ +T+ ++P T + ++P S+ TP+ + T VV++ Sbjct: 890 ----VDTSTPVTNSTEARSSPTTSEGTSMPTSTPG----EGSTPLTSMPDSTTPVVSSEA 941 Query: 194 KPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLKAENSAAVQINLSP 253 + S V T V T +T T P++ +S P++ P+ + +S Sbjct: 942 RTLSATPVDTSTPVTT-------STEATSSPTTAEGTSIPTSTPS--EGTTPLTSTPVSH 992 Query: 254 TMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRKLYVELKS 313 T++ N + A + S +P L EA S Sbjct: 993 TLVANSE------ASTLSTTPVDSNTP-------------LTTSTEA------------S 1021 Query: 314 SPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTT---T 370 SP P + P ++ S+ MV ++ T+T++T+P T+ T Sbjct: 1022 SPPPTAEGTSMPTSTPSEGSTPLTR-------MPVSTTMVASSETSTLSTTPADTSTPVT 1074 Query: 371 VSSSQSEKSIIVSGATAPRTVSVQTLNPLAG-------------------PVGAKAGVVT 411 S S S G + P + + PL PV V T Sbjct: 1075 TYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTT 1134 Query: 412 L--HSVGPTAATG----------GTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSG 459 S PT A G GTT + ++ +V+S ANT++T + + V + Sbjct: 1135 STEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATS 1194 Query: 460 --------TAVTLSLPAVTFGETSGAAICLP-SVKPVVSS-AGTTSDKPV-IGTPVQIK- 507 TA S+P T GE S +P PV SS A T S PV TPV Sbjct: 1195 TEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSA 1254 Query: 508 -----------LAQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNEKQVTTISHSSTLTIQK 556 + P S+ + + ++ V +V P + +T + Sbjct: 1255 ETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNE 1314 Query: 557 CGQKTMPV-NTIIPTSQF-----PPASILKQITLPGNKILSLQASPTQKNRIKENVTSCF 610 P T +PTS + P SI TL + +S+ ++ N ++ Sbjct: 1315 VSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEA 1374 Query: 611 RDEDDINDVTSMAGVNLNE 629 ++ TSM N +E Sbjct: 1375 CSSPTTSEGTSMPNSNPSE 1393 Score = 53.9 bits (128), Expect = 6e-07 Identities = 107/521 (20%), Positives = 196/521 (37%), Gaps = 61/521 (11%) Query: 5 LTEPAGAAPPAAVSASGT--VTMAPAGA---LPVRVESTPVALGAVTKAPVSVCVEPTAS 59 ++ P+ + P + T VT++ AG LPV + + V+ +PV+ + Sbjct: 3627 MSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVT---PEGTT 3683 Query: 60 QPLRSPV-GTLVTKVAPVSAPPKVSS-GPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTV 117 P+ +P G+ PVS SS G L P +V T+T ++ L T+ Sbjct: 3684 MPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTM 3743 Query: 118 LIK-----SNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQ--LI 170 + S G +LVS T T +S P++P+ ++ + T SS + Sbjct: 3744 SVSMPMEISTLGTTILVS-----TTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTL 3798 Query: 171 KKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGK---PLNTVTTLKPSSL 227 + P+ ++ T + T + P SV S + S ++ PG PL T T S+ Sbjct: 3799 EGTTTMPMSTTSERSTLLTTVLISPISVMSPS-EASTLSTPPGDTSTPLLTSTKAGSFSI 3857 Query: 228 GASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVK 287 A T ++ + +S T+ + + + + + S + Sbjct: 3858 PAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPT 3917 Query: 288 KLVEQLLDAKIEAEEFTRKLYVELKSSPQ--------PHLVPFLKKSVVALRQL-LPNSQ 338 V + + E T + + S+P P + V+ +L P++ Sbjct: 3918 IPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTS 3977 Query: 339 SFIQQCVQQTSSDMVIATCTT-------TVTTSPVVTTTVSSSQSEKSIIVSGATAPRTV 391 S T+ + TT T++T+P T S + + +S + P T Sbjct: 3978 SSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTS 4037 Query: 392 SVQTLNPLA-GPVGAKAGVVTLHSVGPT-----AATGGTT----------AGTGLLQTSK 435 + T P+ ++ +T H++ PT ++T TT A T + +K Sbjct: 4038 TSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTK 4097 Query: 436 PLV-TSVANTVTTVSLQPEKPVVSGTAVTLSLPAVT--FGE 473 P T+ TVTT ++ + S T ++P T FG+ Sbjct: 4098 PSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVPRTTTCFGD 4138 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 70.1 bits (170), Expect = 8e-12 Identities = 125/590 (21%), Positives = 190/590 (32%), Gaps = 77/590 (13%) Query: 12 APPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGT-LV 70 +PP + + T P+ P +P + T P + PT + P T Sbjct: 1563 SPPPTTTTTPPPTTTPSP--PTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSP 1620 Query: 71 TKVAPVSAPPKVSSGP--RLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLML 128 P++ P ++ P P+P P TT P P + + P Sbjct: 1621 PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTT 1680 Query: 129 VSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTV 188 S T T + T+ +T+ + T P+S++ TP + T Sbjct: 1681 PSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTT--------TPSPPPTTMTTPS 1732 Query: 189 VTTVPKPSSVQSVAVP----TSVVTVTPGKPLNTVTTLKPSSLGASSTP----------- 233 TT P P + +P +S +T TP P T T P S +TP Sbjct: 1733 PTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWL 1792 Query: 234 -SNEPNLKAENSAAVQIN--LSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLV 290 S +PN I P N+ C+ + + + ++GQ V V Sbjct: 1793 DSGKPNFHKPGGDTELIGDVCGPGWAANI-SCRATMYPDVPIG-------QLGQTVVCDV 1844 Query: 291 EQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSS 350 L K E + K V N + +Q C T Sbjct: 1845 SVGLICKNEDQ----------------------KPGGVIPMAFCLNYEINVQCCECVTQP 1882 Query: 351 DMVIATCT---TTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAK- 406 + T T T TT+P+ TTT + + + T P T + T+ P P G + Sbjct: 1883 TTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQT 1941 Query: 407 ---AGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVT 463 + T +V PT GT T T+ VT T T P+ + T VT Sbjct: 1942 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVT 2000 Query: 464 -LSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQ-PAGI 521 P T T+ +V P + GT + T P P +Q P Sbjct: 2001 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2060 Query: 522 PQAVQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKTMPVNTIIPTS 571 P P+G T I+ ++T+T P T PT+ Sbjct: 2061 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGTQTPTT 2105 Score = 69.3 bits (168), Expect = 1e-11 Identities = 132/633 (20%), Positives = 199/633 (31%), Gaps = 84/633 (13%) Query: 8 PAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVG 67 P G P + T T+ P TP T P++ T P +P G Sbjct: 3684 PTGTQTPTTTPITTTTTVTPT--------PTPTGTQTPTTTPITTTTTVT---PTPTPTG 3732 Query: 68 TLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQF---------PANLQLPPGTVL 118 T P++ V+ P P + P TT I P Q P T + Sbjct: 3733 TQTPTTTPITTTTTVT-----PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3787 Query: 119 IKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPV 178 + + + +P T T+ TT+ IT+ V P T + V TP Sbjct: 3788 TTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3844 Query: 179 KKLAQIGTTV-------VTTVPKPSSVQS-----VAVPTSVV-TVTP-GKPLNTVTTLKP 224 Q TT VT P P+ Q+ + T+V T TP G T T + Sbjct: 3845 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3904 Query: 225 SSLGASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQ 284 ++ + ++PT + + + + +P Q Sbjct: 3905 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3964 Query: 285 NVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQ----PHLVPFLKKSVVALRQLLPNSQSF 340 T V +P P P + V +Q+ Sbjct: 3965 TPT------------TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 4012 Query: 341 IQQCVQQTSS--DMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNP 398 + T++ T T T TT+P+ TTT + + + T P T + T+ P Sbjct: 4013 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTP 4071 Query: 399 LAGPVGAKAG----VVTLHSVGPTAATGGT--------TAGTGLLQTSKPLVTSVANT-- 444 P G + + T +V PT GT T T + T P T T Sbjct: 4072 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4131 Query: 445 VTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPV 504 +TT + P +GT + P T P+ P + TT+ P+ T Sbjct: 4132 ITTTTTVTPTPTPTGTQTPTTTPITT------TTTVTPTPTPTGTQTPTTT--PITTTTT 4183 Query: 505 QIKLAQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKTMPV 564 P + P + +L P + T+ S SS LT T+P Sbjct: 4184 VTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLP- 4242 Query: 565 NTIIPTSQFPPASILKQITLPGNKILSLQASPT 597 I TS PP++ T G LS S T Sbjct: 4243 PAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTT 4275 Score = 68.9 bits (167), Expect = 2e-11 Identities = 122/587 (20%), Positives = 187/587 (31%), Gaps = 72/587 (12%) Query: 8 PAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVG 67 P G P + T T+ P TP T P++ T P +P G Sbjct: 1913 PTGTQTPTTTPITTTTTVTPT--------PTPTGTQTPTTTPITTTTTVT---PTPTPTG 1961 Query: 68 TLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQF---------PANLQLPPGTVL 118 T P++ V+ P P + P TT I P Q P T + Sbjct: 1962 TQTPTTTPITTTTTVT-----PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2016 Query: 119 IKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPV 178 + + V+P T T +T + P T +++ + VTP Sbjct: 2017 TTTTT-----VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2071 Query: 179 KKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTP-GKPLNTVTTLKPS-SLGASSTPSNE 236 GT TT P ++ PT T TP P+ T TT+ P+ + + TP+ Sbjct: 2072 P--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2129 Query: 237 PNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDA 296 P + + + T + +G+Q+P Sbjct: 2130 P-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---------------- 2172 Query: 297 KIEAEEFTRKLYVELKSSP----QPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDM 352 T V +P P P + V +Q+ + T++ Sbjct: 2173 --TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2230 Query: 353 VIATCT--TTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAK---- 406 T T T TT+P+ TTT + + + T P T + T+ P P G + Sbjct: 2231 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTT 2289 Query: 407 AGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVT-LS 465 + T +V PT GT T T+ VT T T P+ + T VT Sbjct: 2290 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTP 2348 Query: 466 LPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQ-PAGIPQA 524 P T T+ +V P + GT + T P P +Q P P Sbjct: 2349 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2408 Query: 525 VQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKTMPVNTIIPTS 571 P+G T I+ ++T+T P T PT+ Sbjct: 2409 TTTTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGTQTPTT 2450 Score = 68.9 bits (167), Expect = 2e-11 Identities = 122/587 (20%), Positives = 187/587 (31%), Gaps = 72/587 (12%) Query: 8 PAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVG 67 P G P + T T+ P TP T P++ T P +P G Sbjct: 2235 PTGTQTPTTTPITTTTTVTPT--------PTPTGTQTPTTTPITTTTTVT---PTPTPTG 2283 Query: 68 TLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQF---------PANLQLPPGTVL 118 T P++ V+ P P + P TT I P Q P T + Sbjct: 2284 TQTPTTTPITTTTTVT-----PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2338 Query: 119 IKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPV 178 + + V+P T T +T + P T +++ + VTP Sbjct: 2339 TTTTT-----VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2393 Query: 179 KKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTP-GKPLNTVTTLKPS-SLGASSTPSNE 236 GT TT P ++ PT T TP P+ T TT+ P+ + + TP+ Sbjct: 2394 P--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2451 Query: 237 PNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDA 296 P + + + T + +G+Q+P Sbjct: 2452 P-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---------------- 2494 Query: 297 KIEAEEFTRKLYVELKSSP----QPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDM 352 T V +P P P + V +Q+ + T++ Sbjct: 2495 --TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2552 Query: 353 VIATCT--TTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAK---- 406 T T T TT+P+ TTT + + + T P T + T+ P P G + Sbjct: 2553 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTT 2611 Query: 407 AGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVT-LS 465 + T +V PT GT T T+ VT T T P+ + T VT Sbjct: 2612 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTP 2670 Query: 466 LPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQ-PAGIPQA 524 P T T+ +V P + GT + T P P +Q P P Sbjct: 2671 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2730 Query: 525 VQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKTMPVNTIIPTS 571 P+G T I+ ++T+T P T PT+ Sbjct: 2731 TTTTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGTQTPTT 2772 Score = 68.9 bits (167), Expect = 2e-11 Identities = 122/587 (20%), Positives = 187/587 (31%), Gaps = 72/587 (12%) Query: 8 PAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVG 67 P G P + T T+ P TP T P++ T P +P G Sbjct: 2557 PTGTQTPTTTPITTTTTVTPT--------PTPTGTQTPTTTPITTTTTVT---PTPTPTG 2605 Query: 68 TLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQF---------PANLQLPPGTVL 118 T P++ V+ P P + P TT I P Q P T + Sbjct: 2606 TQTPTTTPITTTTTVT-----PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2660 Query: 119 IKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPV 178 + + V+P T T +T + P T +++ + VTP Sbjct: 2661 TTTTT-----VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2715 Query: 179 KKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTP-GKPLNTVTTLKPS-SLGASSTPSNE 236 GT TT P ++ PT T TP P+ T TT+ P+ + + TP+ Sbjct: 2716 P--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2773 Query: 237 PNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDA 296 P + + + T + +G+Q+P Sbjct: 2774 P-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---------------- 2816 Query: 297 KIEAEEFTRKLYVELKSSP----QPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDM 352 T V +P P P + V +Q+ + T++ Sbjct: 2817 --TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2874 Query: 353 VIATCT--TTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAK---- 406 T T T TT+P+ TTT + + + T P T + T+ P P G + Sbjct: 2875 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTT 2933 Query: 407 AGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVT-LS 465 + T +V PT GT T T+ VT T T P+ + T VT Sbjct: 2934 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTP 2992 Query: 466 LPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQ-PAGIPQA 524 P T T+ +V P + GT + T P P +Q P P Sbjct: 2993 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3052 Query: 525 VQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKTMPVNTIIPTS 571 P+G T I+ ++T+T P T PT+ Sbjct: 3053 TTTTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGTQTPTT 3094 Score = 68.9 bits (167), Expect = 2e-11 Identities = 122/587 (20%), Positives = 187/587 (31%), Gaps = 72/587 (12%) Query: 8 PAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVG 67 P G P + T T+ P TP T P++ T P +P G Sbjct: 2879 PTGTQTPTTTPITTTTTVTPT--------PTPTGTQTPTTTPITTTTTVT---PTPTPTG 2927 Query: 68 TLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQF---------PANLQLPPGTVL 118 T P++ V+ P P + P TT I P Q P T + Sbjct: 2928 TQTPTTTPITTTTTVT-----PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2982 Query: 119 IKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPV 178 + + V+P T T +T + P T +++ + VTP Sbjct: 2983 TTTTT-----VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3037 Query: 179 KKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTP-GKPLNTVTTLKPS-SLGASSTPSNE 236 GT TT P ++ PT T TP P+ T TT+ P+ + + TP+ Sbjct: 3038 P--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3095 Query: 237 PNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDA 296 P + + + T + +G+Q+P Sbjct: 3096 P-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---------------- 3138 Query: 297 KIEAEEFTRKLYVELKSSP----QPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDM 352 T V +P P P + V +Q+ + T++ Sbjct: 3139 --TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3196 Query: 353 VIATCT--TTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAK---- 406 T T T TT+P+ TTT + + + T P T + T+ P P G + Sbjct: 3197 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTT 3255 Query: 407 AGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVT-LS 465 + T +V PT GT T T+ VT T T P+ + T VT Sbjct: 3256 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTP 3314 Query: 466 LPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQ-PAGIPQA 524 P T T+ +V P + GT + T P P +Q P P Sbjct: 3315 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3374 Query: 525 VQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKTMPVNTIIPTS 571 P+G T I+ ++T+T P T PT+ Sbjct: 3375 TTTTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGTQTPTT 3416 Score = 68.9 bits (167), Expect = 2e-11 Identities = 122/587 (20%), Positives = 187/587 (31%), Gaps = 72/587 (12%) Query: 8 PAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVG 67 P G P + T T+ P TP T P++ T P +P G Sbjct: 3201 PTGTQTPTTTPITTTTTVTPT--------PTPTGTQTPTTTPITTTTTVT---PTPTPTG 3249 Query: 68 TLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQF---------PANLQLPPGTVL 118 T P++ V+ P P + P TT I P Q P T + Sbjct: 3250 TQTPTTTPITTTTTVT-----PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3304 Query: 119 IKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPV 178 + + V+P T T +T + P T +++ + VTP Sbjct: 3305 TTTTT-----VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3359 Query: 179 KKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTP-GKPLNTVTTLKPS-SLGASSTPSNE 236 GT TT P ++ PT T TP P+ T TT+ P+ + + TP+ Sbjct: 3360 P--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3417 Query: 237 PNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDA 296 P + + + T + +G+Q+P Sbjct: 3418 P-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---------------- 3460 Query: 297 KIEAEEFTRKLYVELKSSP----QPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDM 352 T V +P P P + V +Q+ + T++ Sbjct: 3461 --TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3518 Query: 353 VIATCT--TTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAK---- 406 T T T TT+P+ TTT + + + T P T + T+ P P G + Sbjct: 3519 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTT 3577 Query: 407 AGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVT-LS 465 + T +V PT GT T T+ VT T T P+ + T VT Sbjct: 3578 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTP 3636 Query: 466 LPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQ-PAGIPQA 524 P T T+ +V P + GT + T P P +Q P P Sbjct: 3637 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3696 Query: 525 VQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKTMPVNTIIPTS 571 P+G T I+ ++T+T P T PT+ Sbjct: 3697 TTTTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGTQTPTT 3738 Score = 68.9 bits (167), Expect = 2e-11 Identities = 122/587 (20%), Positives = 187/587 (31%), Gaps = 72/587 (12%) Query: 8 PAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVG 67 P G P + T T+ P TP T P++ T P +P G Sbjct: 3523 PTGTQTPTTTPITTTTTVTPT--------PTPTGTQTPTTTPITTTTTVT---PTPTPTG 3571 Query: 68 TLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQF---------PANLQLPPGTVL 118 T P++ V+ P P + P TT I P Q P T + Sbjct: 3572 TQTPTTTPITTTTTVT-----PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3626 Query: 119 IKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPV 178 + + V+P T T +T + P T +++ + VTP Sbjct: 3627 TTTTT-----VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3681 Query: 179 KKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTP-GKPLNTVTTLKPS-SLGASSTPSNE 236 GT TT P ++ PT T TP P+ T TT+ P+ + + TP+ Sbjct: 3682 P--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3739 Query: 237 PNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDA 296 P + + + T + +G+Q+P Sbjct: 3740 P-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---------------- 3782 Query: 297 KIEAEEFTRKLYVELKSSP----QPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDM 352 T V +P P P + V +Q+ + T++ Sbjct: 3783 --TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3840 Query: 353 VIATCT--TTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAK---- 406 T T T TT+P+ TTT + + + T P T + T+ P P G + Sbjct: 3841 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTT 3899 Query: 407 AGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVT-LS 465 + T +V PT GT T T+ VT T T P+ + T VT Sbjct: 3900 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTPTP 3958 Query: 466 LPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQ-PAGIPQA 524 P T T+ +V P + GT + T P P +Q P P Sbjct: 3959 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4018 Query: 525 VQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKTMPVNTIIPTS 571 P+G T I+ ++T+T P T PT+ Sbjct: 4019 TTTTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGTQTPTT 4060 Score = 67.8 bits (164), Expect = 4e-11 Identities = 122/589 (20%), Positives = 187/589 (31%), Gaps = 72/589 (12%) Query: 6 TEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSP 65 T PP + T T+ P TP T P++ T P +P Sbjct: 1888 TTTENPTPPTTTPITTTTTVTPT--------PTPTGTQTPTTTPITTTTTVT---PTPTP 1936 Query: 66 VGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQF---------PANLQLPPGT 116 GT P++ V+ P P + P TT I P Q P T Sbjct: 1937 TGTQTPTTTPITTTTTVT-----PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 1991 Query: 117 VLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVT 176 + + + V+P T T +T + P T +++ + VT Sbjct: 1992 PITTTTT-----VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2046 Query: 177 PVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTP-GKPLNTVTTLKPS-SLGASSTPS 234 P GT TT P ++ PT T TP P+ T TT+ P+ + + TP+ Sbjct: 2047 PTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2104 Query: 235 NEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLL 294 P + + + T + +G+Q+P Sbjct: 2105 TTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-------------- 2149 Query: 295 DAKIEAEEFTRKLYVELKSSP----QPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSS 350 T V +P P P + V +Q+ + T++ Sbjct: 2150 ----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2205 Query: 351 DMVIATCT--TTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAK-- 406 T T T TT+P+ TTT + + + T P T + T+ P P G + Sbjct: 2206 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTP 2264 Query: 407 --AGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVT- 463 + T +V PT GT T T+ VT T T P+ + T VT Sbjct: 2265 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTPTTTPITTTTTVTP 2323 Query: 464 LSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQ-PAGIP 522 P T T+ +V P + GT + T P P +Q P P Sbjct: 2324 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2383 Query: 523 QAVQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKTMPVNTIIPTS 571 P+G T I+ ++T+T P T PT+ Sbjct: 2384 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-----PTPTPTGTQTPTT 2427 Score = 64.7 bits (156), Expect = 4e-10 Identities = 108/514 (21%), Positives = 167/514 (32%), Gaps = 87/514 (16%) Query: 8 PAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVG 67 P G P + T T+ P TP T P++ T P +P G Sbjct: 3845 PTGTQTPTTTPITTTTTVTPT--------PTPTGTQTPTTTPITTTTTVT---PTPTPTG 3893 Query: 68 TLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQF---------PANLQLPPGTVL 118 T P++ V+ P P + P TT I P Q P T + Sbjct: 3894 TQTPTTTPITTTTTVT-----PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3948 Query: 119 IKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPV 178 + + V+P T T +T + P T +++ + VTP Sbjct: 3949 TTTTT-----VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4003 Query: 179 KKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTP-GKPLNTVTTLKPS-SLGASSTPSNE 236 GT TT P ++ PT T TP P+ T TT+ P+ + + TP+ Sbjct: 4004 P--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4061 Query: 237 PNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDA 296 P + + +PT +G+Q+P Sbjct: 4062 P-----ITTTTTVTPTPTP-------------------TGTQTP---------------- 4081 Query: 297 KIEAEEFTRKLYVELKSSP----QPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDM 352 T V +P P P + V +Q+ + T++ Sbjct: 4082 --TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4139 Query: 353 VIATCTTT--VTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVV 410 T T T TT+P+ TTT + + + T P T + T+ P P G + G Sbjct: 4140 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTGPP 4198 Query: 411 TLHSVGPTA--ATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPA 468 T S P A T + QTS+ + + + T +S P ++ TA + A Sbjct: 4199 THTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTA 4258 Query: 469 VTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGT 502 T TSG P S GT + G+ Sbjct: 4259 PT--TTSGGHTLSPPPSTTTSPPGTPTRGTTTGS 4290 Score = 59.7 bits (143), Expect = 1e-08 Identities = 54/199 (27%), Positives = 73/199 (36%), Gaps = 15/199 (7%) Query: 49 PVSVCVE-PTASQPLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFP 107 P+ C+ P+ SP T T + P + P ++ P P TTT P Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPP 1450 Query: 108 ANLQLPPGTVLIK-----SNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTV 162 PP + + S P SP T TT+ T P +P T T Sbjct: 1451 TTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP 1510 Query: 163 PNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTV----TPGKPLNT 218 P S++ L TP T TT P P + + PTS T+ TP P T Sbjct: 1511 PASTTTL--PPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTT 1568 Query: 219 VTTLKPS---SLGASSTPS 234 TT P+ S ++TPS Sbjct: 1569 TTTPPPTTTPSPPTTTTPS 1587 Score = 59.3 bits (142), Expect = 1e-08 Identities = 62/250 (24%), Positives = 84/250 (33%), Gaps = 36/250 (14%) Query: 12 APPAAVSA--SGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTL 69 +PP + + T T P P +TP+ P S P + P SP T Sbjct: 1478 SPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT------PPASTTTLPPTTTP--SPPTTT 1529 Query: 70 VTKVAPVSAPPKVSSGPRLPA------PQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNS 123 T P + P ++ P P P P TTT P P T S Sbjct: 1530 TTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPP 1589 Query: 124 GPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQ 183 P T TT+ T P +P T T P S++ L TP Sbjct: 1590 TITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTL--PPTTTPSPPPTT 1647 Query: 184 IGTTVVTTVPKPSSVQS-------------VAVPTSVVTVTPGKPLNTVTTLKP-----S 225 T TT P P + + P+S +T TP P T+TT P S Sbjct: 1648 TTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSS 1707 Query: 226 SLGASSTPSN 235 + ++TPS+ Sbjct: 1708 PITTTTTPSS 1717 Score = 59.3 bits (142), Expect = 1e-08 Identities = 60/243 (24%), Positives = 85/243 (34%), Gaps = 20/243 (8%) Query: 6 TEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSP 65 T P P+ + + A LP +P T P + PT + P+ P Sbjct: 1492 TTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTT-PITPP 1550 Query: 66 VGTLVTKVAPV---SAPPKVSSGP---RLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLI 119 T T + P S PP ++ P P+P +P T T P P Sbjct: 1551 TST--TTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTT 1608 Query: 120 KSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVK 179 + P SP T TS T P +P T P +++ TP Sbjct: 1609 TTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP-SPPTTTTPSP 1667 Query: 180 KLAQIGTTVVTTVPKPSSVQSVAVPTSVV-----TVTPGKPLNTVTTLKPSSLGASSTPS 234 + T TT P + + PT+ + T TP P+ T TT PSS ++TPS Sbjct: 1668 PITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTT--PSS---TTTPS 1722 Query: 235 NEP 237 P Sbjct: 1723 PPP 1725 Score = 59.3 bits (142), Expect = 1e-08 Identities = 98/486 (20%), Positives = 148/486 (30%), Gaps = 64/486 (13%) Query: 8 PAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVG 67 P G P + T T+ P TP T P++ T P +P G Sbjct: 3868 PTGTQTPTTTPITTTTTVTPT--------PTPTGTQTPTTTPITTTTTVT---PTPTPTG 3916 Query: 68 TLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQF---------PANLQLPPGTVL 118 T P++ V+ P P + P TT I P Q P T + Sbjct: 3917 TQTPTTTPITTTTTVT-----PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3971 Query: 119 IKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPV 178 + + + +P T T+ TT+ IT+ V P T + V TP Sbjct: 3972 TTTTT---VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4028 Query: 179 KKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGK-PLNTVTTLKPSSLGASSTPSNEP 237 GT TT P ++ PT T TP P+ T TT+ P+ + Sbjct: 4029 PT----GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4084 Query: 238 NLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAK 297 + + + T + +G+Q+P Sbjct: 4085 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT---------------- 4128 Query: 298 IEAEEFTRKLYVELKSSPQ----PHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMV 353 T V +P P P + V +Q+ + T++ Sbjct: 4129 --TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4186 Query: 354 IATCTTTVT-------TSPVVTTTVSSSQSEKSIIVSG--ATAPRTVSVQTLNPLAGPVG 404 T T T T T+P+ T S+ E S + ++P T S L+ L + Sbjct: 4187 TPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIE 4246 Query: 405 AKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTL 464 + PT +GG T T+ P T T T S P V T + Sbjct: 4247 MTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSA 4306 Query: 465 SLPAVT 470 P T Sbjct: 4307 WTPTPT 4312 Score = 58.5 bits (140), Expect = 3e-08 Identities = 50/237 (21%), Positives = 77/237 (32%), Gaps = 10/237 (4%) Query: 6 TEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSP 65 T P P+ + + LP +P T P + PT + P Sbjct: 1531 TTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPT 1590 Query: 66 VGTLVTKVAPVSAPPKVSSGPRLPA-----PQIVAVKAPNTTTIQFPANLQLPPGTVLIK 120 + T +PP ++ P P + P +TT P PP T Sbjct: 1591 ITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTT-- 1648 Query: 121 SNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKK 180 + P SP T T + + T+ P + P +++ TP Sbjct: 1649 TTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSP 1708 Query: 181 LAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEP 237 + T TT P P + T T TP P T+TTL P++ + T + P Sbjct: 1709 ITTTTTPSSTTTPSPPPT---TMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLP 1762 Score = 53.5 bits (127), Expect = 8e-07 Identities = 58/230 (25%), Positives = 74/230 (32%), Gaps = 27/230 (11%) Query: 13 PPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTLVTK 72 P S T T P P S P+ T P + P S P T + Sbjct: 1418 PTTTPSPPTTTTTTPP---PTTTPSPPIT--TTTTPPPTTTPSPPISTTTTPPPTTTPSP 1472 Query: 73 VAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLVSPQ 132 +PP + P TTT P PP T I + L P Sbjct: 1473 PTTTPSPPTTTPSP-----------PTTTTTTPPPTTTPSPPTTTPITPPASTTTL--PP 1519 Query: 133 QTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTV 192 T TT+ T P +P T T P S++ L TP T TT Sbjct: 1520 TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTL--PPTTTPSPPPTTTTTPPPTTT 1577 Query: 193 PKPSSVQSVAVPTSVV-----TVTPGKPLNTVTTLKPSSLGASSTPSNEP 237 P P + + + PT T TP P T TT P++ S P+ P Sbjct: 1578 PSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTT--TPSPPTTTP 1625 Score = 36.6 bits (83), Expect = 0.10 Identities = 55/235 (23%), Positives = 73/235 (31%), Gaps = 20/235 (8%) Query: 358 TTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGP 417 TTT TT P TT + + + S T P T + P P T P Sbjct: 1527 TTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTT-----PSPPPTTTTTPPPTTTPSPP 1581 Query: 418 TAATGG-----TTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFG 472 T T TT S P T+ TT P ++ T +LP T Sbjct: 1582 TTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP 1641 Query: 473 ETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLVV 532 P S TT+ P I T P S P + + Sbjct: 1642 SPPPTTTTTPPPTTTPSPPTTTTPSPPITTTT---TPPPTTTPSSPITTTPSPPTTTMTT 1698 Query: 533 QQPSGGNEKQVTTISHSSTLTIQKCGQKTM--PVNTIIPTSQFPPASILKQITLP 585 P+ +TT + S+ T TM P T P+ PP + + TLP Sbjct: 1699 PSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPS---PPTTTM--TTLP 1748 Score = 30.4 bits (67), Expect = 7.4 Identities = 45/237 (18%), Positives = 68/237 (28%), Gaps = 12/237 (5%) Query: 341 IQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLA 400 + +C+ S + T TT+ TTT S + + T ++ T P Sbjct: 1392 MDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPT 1451 Query: 401 GPVGAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGT 460 T T + TT S P T+ TT P ++ Sbjct: 1452 TTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPP 1511 Query: 461 AVTLSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAG 520 A T +LP T P + TT+ P TP+ P + P Sbjct: 1512 ASTTTLPPTTTPS--------PPTTTTTTPPPTTTPSPPTTTPI----TPPTSTTTLPPT 1559 Query: 521 IPQAVQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKTMPVNTIIPTSQFPPAS 577 + P+ TT T+T T P T+ PP + Sbjct: 1560 TTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTT 1616 >gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] Length = 5765 Score = 63.5 bits (153), Expect = 8e-10 Identities = 117/593 (19%), Positives = 209/593 (35%), Gaps = 60/593 (10%) Query: 10 GAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTL 69 G P ++S + + G + E T A + + + P + + Sbjct: 4229 GHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSP 4288 Query: 70 VTKVAPVSAPPKVSSGPR----LPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGP 125 T S+ SS PR LP A K+ T+ P++ GT+ Sbjct: 4289 ATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTL-------- 4340 Query: 126 LMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIG 185 P+QT T T S I P+ + P+T TV + + + + T Sbjct: 4341 -----PEQTTTPVATMSTI--HPS--STPETTHTSTVLTTKATTTRATSSTSTPSSTPGT 4391 Query: 186 TTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLN----TVTTLKPSSLGASSTPSNEPNL-- 239 T ++T + ++ + PT+ + TPG T T +S G+++TPS+ P Sbjct: 4392 TWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTW 4451 Query: 240 ---KAENSAAVQINLSPTMLENVKKCKNFLAMLIKLAC-----SGSQSPEMGQNVKKLVE 291 + +A V + T + + + A S +P + Sbjct: 4452 ILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALP 4511 Query: 292 QLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSD 351 L + A T + + SS L ++ + + S + V +S Sbjct: 4512 AL---RSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVH--TST 4566 Query: 352 MVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVT 411 ++ AT TTT T V T + + + + + + T T + P + P A V Sbjct: 4567 VLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTAT-----PSSSPGTALTPPVW 4621 Query: 412 LHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTF 471 + + T TT+G+ + +S P T A +TT + V +G+ T S + Sbjct: 4622 ISTTTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTT----TTVATGSMATPS----SS 4673 Query: 472 GETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLV 531 +TSG L + +++ G+T++ TP + PVL+ A P A K Sbjct: 4674 TQTSGTPPSLTTTATTITATGSTTNPS--STPGTTPIT---PVLTSTATTPAATSSKATS 4728 Query: 532 VQQPSGGNEKQV--TTISHSSTLTIQKCGQKTMPVNTIIPTSQFPPASILKQI 582 P V +T + S+ + T+ +P P S + I Sbjct: 4729 SSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTI 4781 Score = 59.7 bits (143), Expect = 1e-08 Identities = 113/521 (21%), Positives = 182/521 (34%), Gaps = 78/521 (14%) Query: 5 LTEPAGAAP---PAAVSASGTVTMAPAGALPVRVESTPVAL-----------GAVTKAPV 50 LTEP+ A P +A+ + T A AG V +T + G T P Sbjct: 4453 LTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPA 4512 Query: 51 --SVCVEPTASQPLRSP---VGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQ 105 S PTA+ P +GT T+++ + P S P +T + Sbjct: 4513 LRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMS---TATPSSTPETVHTSTVLT 4569 Query: 106 FPANLQLPPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQ------TVKI 159 A G+V S++ + T T T+ +S P P T Sbjct: 4570 ATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPT 4629 Query: 160 CTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTV 219 T P +S + ++ A++ TT TTV + S+A P+S + P T Sbjct: 4630 TTTPTTSGSTVTPSSIPGTTHTARVLTTTTTTV----ATGSMATPSSSTQTSGTPPSLTT 4685 Query: 220 TTLKPSSLGASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQS 279 T ++ G+++ PS+ P +P + + S S Sbjct: 4686 TATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSS--------------KATSSSS 4731 Query: 280 PEMGQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQS 339 P + L K A FT P P + +V A ++ S Sbjct: 4732 PRTATTLPVLTSTA--TKSTATSFT----------PIPSSTLWTTWTVPAQTTTPMSTMS 4779 Query: 340 FIQ-QCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIV----SGATAPRTVSVQ 394 I +T+ + T T T+T + T T SS+ I+ + T T S Sbjct: 4780 TIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTA 4839 Query: 395 TLNPLAGPVGAKAGVVTLHSVG-PTA--ATGGTTAGTG----LLQTSKPLVTSVANTVTT 447 TL+ G T+ +V PT AT +T GT ++ T + T+ A+TV Sbjct: 4840 TLSSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATMPTATASTV-- 4897 Query: 448 VSLQPEKPVVSGTAVTLSLPA--VTFGETSGAAICLPSVKP 486 P V T LP+ TF ++ ++ L +++P Sbjct: 4898 ----PSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRP 4934 Score = 59.3 bits (142), Expect = 1e-08 Identities = 118/596 (19%), Positives = 198/596 (33%), Gaps = 83/596 (13%) Query: 11 AAPPAAVSASGTVTMAP--AGALPVRVESTPVALGAVTKAPV---SVCVEPTASQPLRSP 65 A P A S+ T + +P A LPV + ST A + P+ ++ T + +P Sbjct: 3032 ATTPTATSSKATSSSSPRTATTLPV-LTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTP 3090 Query: 66 VGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGP 125 + T+ T + P S P + ++ KA T + PGT I + Sbjct: 3091 MATMST-IHPSSTPETTHTST------VLTTKATTTRATSSMSTPSSTPGTTWILTE--- 3140 Query: 126 LMLVSPQQTVTRAETTSNITSRPAVPAN----------PQTVKICTVPNSSSQLIKKVAV 175 +T A TT+ T A P++ P T TVP S+ Sbjct: 3141 ---------LTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRA 3191 Query: 176 TP--VKKLAQIGTT--VVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSS----- 226 T +K L TT V+++ PSS A + T P T T PSS Sbjct: 3192 TAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTA 3251 Query: 227 ---LGASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMG 283 L ++TP+ + +S ++ S + + ++ + G+ Sbjct: 3252 WTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKV 3311 Query: 284 QNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQ 343 + T +++ ++P S+ Sbjct: 3312 PTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGT------------- 3358 Query: 344 CVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGP- 402 T + V+ T TTTV T + T + S+ S ++ T + T NP + P Sbjct: 3359 ----THTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPG 3414 Query: 403 VGAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAV 462 V+T + P A + T + L T P V + T SL P P TA Sbjct: 3415 TTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAW 3474 Query: 463 TLSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTP---VQIKLAQPGPVLSQPA 519 T + + + S P +++ T P + +P + + P P + P Sbjct: 3475 TSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPG 3534 Query: 520 GIPQAVQVKQLVVQQPSGGNEKQVT-TISHSSTLTIQKCGQKTMPVNTIIPTSQFP 574 G + T T S + T T+ + P+ T++ T P Sbjct: 3535 --------------HTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEP 3576 Score = 55.5 bits (132), Expect = 2e-07 Identities = 128/561 (22%), Positives = 185/561 (32%), Gaps = 73/561 (13%) Query: 2 PAGLTEPAGAAPPAAVSASGTVTMAP--AGALPVRVES-TPVALGAVTKAPVSVC-VEPT 57 P LT PA P A S+ T + +P A LPV + T +VT P S T Sbjct: 4282 PKVLTSPA--TTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGT 4339 Query: 58 ASQPLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTV 117 + +PV T+ T + P S P + ++ KA T + PGT Sbjct: 4340 LPEQTTTPVATMST-IHPSSTPETTHTST------VLTTKATTTRATSSTSTPSSTPGTT 4392 Query: 118 LIKSN----------SGPLMLVS--PQQT-----VTRAETTSNITSRPAVPAN------- 153 I + +GP S P T +T TT+ T A P++ Sbjct: 4393 WILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWI 4452 Query: 154 ---PQTVKICTVPNSSSQLIKKV---AVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSV 207 P T TVP S+ A TP TV ++ PSS A Sbjct: 4453 LTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPA 4512 Query: 208 VTVTPGKPLNT-VTTLKPSSLGASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFL 266 + T P T T + SSLG + T ++ + + +P E V Sbjct: 4513 LRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTP---ETVHTSTVLT 4569 Query: 267 AMLIKLACSG-----SQSPEMGQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVP 321 A +G S +P K T SSP L P Sbjct: 4570 ATATTTGATGSVATPSSTPGTAHTTK-----------VPTTTTTGFTATPSSSPGTALTP 4618 Query: 322 --FLKKSVVALRQLLPNSQSFI--QQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSE 377 ++ + S S + T + V+ T TTTV T + T + S+ S Sbjct: 4619 PVWISTTTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSG 4678 Query: 378 KSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAATG--GTTAGTGLLQTSK 435 ++ T + T NP + P V + AAT T++ + T+ Sbjct: 4679 TPPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTL 4738 Query: 436 PLVTSVANTVTTVSLQPEKPVVSGTA-VTLSLPAVTFGETSGAAICLPSVKPVVSSAGTT 494 P++TS A T S P+ S T T ++PA T S + S P + T Sbjct: 4739 PVLTSTATKSTATSF---TPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETTHTSTV 4795 Query: 495 SDKPVIGTPVQIKLAQPGPVL 515 T A P L Sbjct: 4796 LTTTATMTRATNSTATPSSTL 4816 Score = 53.9 bits (128), Expect = 6e-07 Identities = 112/513 (21%), Positives = 170/513 (33%), Gaps = 55/513 (10%) Query: 10 GAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTL 69 G P ++S + G + E T A T ++ + P + + Sbjct: 2972 GHCPSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTST 3031 Query: 70 VTKVAPVSAPPKVSSGPR----LPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGP 125 T S+ SS PR LP A K+ T+ P+ GT+ Sbjct: 3032 ATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTL-------- 3083 Query: 126 LMLVSPQQTVTRAETTSNI----TSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKL 181 P+QT T T S I T + T K T +SS L Sbjct: 3084 -----PEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWIL 3138 Query: 182 AQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLKA 241 ++ T TT + + P + +T TVT S+ ASST + LK Sbjct: 3139 TELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKV 3198 Query: 242 ENSAAVQINLSPTMLENVKKCKNFLAMLIKL-ACSGSQSPEMGQNVKKLVEQLLDAKIEA 300 S A +PT++ + + L A + + +V + L Sbjct: 3199 LTSTAT----TPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSL-----G 3249 Query: 301 EEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTT 360 +TR ++ P V +L + + + + T TT Sbjct: 3250 TAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTT 3309 Query: 361 ---VTTSPVVTTTVSSSQS---EKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHS 414 TT+ T T SSS + +S T P T T+ P + P G L + Sbjct: 3310 KVPTTTTTGFTATPSSSPGTALTPPVWISTTTTP-TTRGSTVTPSSIP-GTTHTATVLTT 3367 Query: 415 VGPTAATGGTTAGTGLLQTS--KPLVTSVANTVT----------TVSLQPEKPVVSGTAV 462 T ATG + QTS P +T+ A T+T T P PV++ TA Sbjct: 3368 TTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTAT 3427 Query: 463 TLSLPAVTFGE-TSGAAICLPSVKPVVSSAGTT 494 T PA T T +A+ PV ++ TT Sbjct: 3428 T---PAATSSTVTPSSALGTTHTPPVPNTTATT 3457 Score = 53.5 bits (127), Expect = 8e-07 Identities = 60/247 (24%), Positives = 93/247 (37%), Gaps = 27/247 (10%) Query: 6 TEPAGAAPPAAVSAS-GTVTMAPA----GALPVRVESTPVALGAV--TKAPVSVCVEPTA 58 T P + A S+S GT T PA P TP+ ++ T +S PTA Sbjct: 1947 TTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTA 2006 Query: 59 SQPLRSP--------VGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANL 110 + +P T++T A + + P K P TTT F A Sbjct: 2007 TMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATP 2066 Query: 111 QLPPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLI 170 PGT L P + +S T T T + + ++P T + T +++ + Sbjct: 2067 SSSPGTALT-----PPVWIS---TTTTPTTRGSTVTPSSIPGTTHTATVLTT--TTTTVA 2116 Query: 171 KKVAVTPVKKLAQIGT--TVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLG 228 TP GT ++ TT ++ S P+S TP P+ T T P++ Sbjct: 2117 TGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATS 2176 Query: 229 ASSTPSN 235 + TPS+ Sbjct: 2177 NTVTPSS 2183 Score = 51.6 bits (122), Expect = 3e-06 Identities = 61/255 (23%), Positives = 98/255 (38%), Gaps = 30/255 (11%) Query: 5 LTEPAGAAP---PAAVSASGTVTMAPAGALPVRVES--TPVAL----------GAVTKAP 49 LTEP+ A P +A+ + T A AG L V + TP + G T P Sbjct: 3167 LTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALP 3226 Query: 50 V--SVCVEPTASQPLRSP---VGTLVTKVAPVSAPPK-VSSGPRLPAPQIVAVKAPNTTT 103 S PTA+ P +GT T+++ + P +S+ P+ V TTT Sbjct: 3227 ALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTT 3286 Query: 104 IQFPANLQLPPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQT-VKICTV 162 G+V S++ + T T T+ +S P P + T Sbjct: 3287 ----TTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTT 3342 Query: 163 PNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTL 222 P + + ++ A + TT TTV + S+A P+S + P T T Sbjct: 3343 PTTRGSTVTPSSIPGTTHTATVLTTTTTTV----ATGSMATPSSSTQTSGTPPSLTTTAT 3398 Query: 223 KPSSLGASSTPSNEP 237 ++ G+++ PS+ P Sbjct: 3399 TITATGSTTNPSSTP 3413 Score = 51.6 bits (122), Expect = 3e-06 Identities = 53/227 (23%), Positives = 86/227 (37%), Gaps = 13/227 (5%) Query: 12 APPAAVSASGTVTMAPAGALPVR-VESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTLV 70 A PA S + T T A+P + +T L T ++ +S P + T++ Sbjct: 3781 ALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVL 3840 Query: 71 TKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLVS 130 T A + + P K P TTT F PGT P + +S Sbjct: 3841 TTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTART-----PPVWIS 3895 Query: 131 PQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGT--TV 188 T T + +T +S P P + T ++ + TP GT ++ Sbjct: 3896 TTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSM-----ATPSSSTQTSGTPPSL 3950 Query: 189 VTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSN 235 +TT ++ S P+S TP P+ T T P++ ++ TPS+ Sbjct: 3951 ITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSS 3997 Score = 50.8 bits (120), Expect = 5e-06 Identities = 53/232 (22%), Positives = 89/232 (38%), Gaps = 16/232 (6%) Query: 11 AAPPAAVSASGTV-TMAPAGALPVRVESTPVALGAVTKA---PVSVCVEPTASQPLRSPV 66 A PP ++ + T T+ + A P T AL A+ P + V P S S + Sbjct: 1936 APPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPS----SSL 1991 Query: 67 GTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPL 126 GT T+++ + P S P A +T + A G+V S++ Sbjct: 1992 GTTWTRLSQTTTPTATMS---TATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGT 2048 Query: 127 MLVSPQQTVTRAETTSNITSRPAVPANPQT-VKICTVPNSSSQLIKKVAVTPVKKLAQIG 185 + T T T+ +S P P + T P + + ++ A + Sbjct: 2049 AHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVL 2108 Query: 186 TTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEP 237 TT TTV + S+A P+S + P T T ++ G+++ PS+ P Sbjct: 2109 TTTTTTV----ATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTP 2156 Score = 50.1 bits (118), Expect = 9e-06 Identities = 60/247 (24%), Positives = 95/247 (38%), Gaps = 22/247 (8%) Query: 1 MPAGLTEPAG-----AAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVE 55 +P G T A A P + + T T+ + A P T AL A+ S Sbjct: 3736 VPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALR----STATT 3791 Query: 56 PTASQPLRSP---VGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQL 112 PTA+ P +GT T+++ + P S P A +T + A Sbjct: 3792 PTATSFTAIPSSSLGTTWTRLSQTTTPTATMS---TATPSSTPETAHTSTVLTTTATTTR 3848 Query: 113 PPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQT-VKICTVPNSSSQLIK 171 G+V S++ + T T T +S P P + T P +S + Sbjct: 3849 ATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVT 3908 Query: 172 KVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKP-SSLGAS 230 +V + TT TTV + S+A P+S T T G P + +TT ++ G++ Sbjct: 3909 PSSVPGTTHTPTVLTTTTTTV----ATGSMATPSSS-TQTSGTPPSLITTATTITATGST 3963 Query: 231 STPSNEP 237 + PS+ P Sbjct: 3964 TNPSSTP 3970 Score = 47.4 bits (111), Expect = 6e-05 Identities = 98/444 (22%), Positives = 145/444 (32%), Gaps = 74/444 (16%) Query: 99 PNTTTIQFPANLQLPPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPAN----- 153 P T++ P++ PGT I L T T E+T + + + P Sbjct: 2421 PATSSTAMPSST---PGTTWI--------LTELTTTATTTESTGSTATPSSTPGTTWILT 2469 Query: 154 -PQTVKICTVPNSSSQLIKKV---AVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVT 209 P T TVP S+ A TP TV ++ P S A + Sbjct: 2470 EPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALR 2529 Query: 210 VTPGKPLNTVTTLKPSS--------LGASSTPSNEPNLKAENSAAVQINLSPTMLENVKK 261 T P T T PSS L ++TP+ + +S ++ S T+L Sbjct: 2530 STATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTS-TVLTTTAT 2588 Query: 262 CKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLD---AKIEAEEFTRKLYVELKSSPQPH 318 + + S +P K L + R L V + ++ P Sbjct: 2589 TTGATGSV----ATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTP- 2643 Query: 319 LVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEK 378 + +P + T + V+ T TTTV T + T + S+ S Sbjct: 2644 ----TTRGSTVTPSSIPGT----------THTPTVLTTTTTTVATGSMATPSSSTQTSGT 2689 Query: 379 SIIVSGATAPRTVSVQTLNPLAGP-VGAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPL 437 ++ T + T NP + P V+T + P A + T + L T P Sbjct: 2690 PPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPP 2749 Query: 438 VTSVANTVTTVSLQPEKP---------VVSGTAVTLSL----------PAVTFGETSGAA 478 V + T SL P P SGT T + PA T G T + Sbjct: 2750 VPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHST 2809 Query: 479 ICLPSVKPVVSSAGTTSDKPVIGT 502 L S P S+ TT P GT Sbjct: 2810 PALSSPHP---SSRTTESPPSPGT 2830 Score = 46.6 bits (109), Expect = 1e-04 Identities = 99/468 (21%), Positives = 159/468 (33%), Gaps = 69/468 (14%) Query: 131 PQQTVTRAETTSNITSRPAVPAN-PQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVV 189 P + +T TT TS A ++ P+T V S++ + TP+ +GTT Sbjct: 3024 PPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFT-LGTT-- 3080 Query: 190 TTVPK----PSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPN---LKAE 242 T+P+ P + S P+S T + T + + STPS+ P + E Sbjct: 3081 GTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTE 3140 Query: 243 NSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEE 302 + A + +L + + + + + G + ++ Sbjct: 3141 LTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLT 3200 Query: 303 FTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVT 362 T + S P P ++ ALR +T TT Sbjct: 3201 STATTPTVISSRATPSSSPGTATALPALR-----------------------STATTPTA 3237 Query: 363 TSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAATG 422 TS VT SSS +S T P T ++ T P + P V + T ATG Sbjct: 3238 TS--VTAIPSSSLGTAWTRLSQTTTP-TATMSTATPSSTPETVHTSTVLTTTTTTTRATG 3294 Query: 423 GTTAGT---GLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAI 479 + G T+K T+ T S P GTA+T P V T+ Sbjct: 3295 SVATPSSTPGTAHTTKVPTTTTTGFTATPSSSP------GTALT---PPVWISTTTTPTT 3345 Query: 480 CLPSVKPVVSSAGTTSDKPVIGTPVQI----KLAQPGPVLSQPAGIPQAVQVKQLVVQQP 535 +V P S GTT V+ T +A P +Q +G P ++ Sbjct: 3346 RGSTVTPS-SIPGTTHTATVLTTTTTTVATGSMATPSSS-TQTSGTPPSLTTT------- 3396 Query: 536 SGGNEKQVTTISHSSTLTIQKCGQKTMPVNTIIPTSQFPPASILKQIT 583 TTI+ + + T T P+ ++ T+ PA+ +T Sbjct: 3397 -------ATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVT 3437 Score = 46.2 bits (108), Expect = 1e-04 Identities = 57/247 (23%), Positives = 94/247 (38%), Gaps = 22/247 (8%) Query: 1 MPAGLTEPAG-----AAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVE 55 +P G T A A P + + T T+ + A P T AL A+ S Sbjct: 2479 VPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALR----STATT 2534 Query: 56 PTASQPLRSP---VGTLVTKVAPVSAPPK-VSSGPRLPAPQIVAVKAPNTTTIQFPANLQ 111 PTA+ P +GT T+++ + P +S+ P+ V TTT A Sbjct: 2535 PTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTT----ATTT 2590 Query: 112 LPPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPAN-PQTVKICTVPNSSSQLI 170 G+V S++ + T T T+ +S P P + T P + + Sbjct: 2591 GATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTV 2650 Query: 171 KKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGAS 230 ++ + TT TTV + S+A P+S + P T T ++ G++ Sbjct: 2651 TPSSIPGTTHTPTVLTTTTTTV----ATGSMATPSSSTQTSGTPPSLTTTATTITATGST 2706 Query: 231 STPSNEP 237 + PS+ P Sbjct: 2707 TNPSSTP 2713 Score = 45.8 bits (107), Expect = 2e-04 Identities = 62/257 (24%), Positives = 93/257 (36%), Gaps = 17/257 (6%) Query: 12 APPAAVSASGTVTMAPAGALPVR-VESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTLV 70 A PA S + T T A+P + +T L T ++ +S P T++ Sbjct: 2524 ALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVL 2583 Query: 71 TKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLVS 130 T A + + P K TTT F A PGT + + P+ + + Sbjct: 2584 TTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGT----ARTLPVWIST 2639 Query: 131 PQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVT 190 TR T + +S P P + T ++ + + T TT T Sbjct: 2640 TTTPTTRGSTVTP-SSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTAT 2698 Query: 191 TVP------KPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSS-LGASSTPSNEPNLKAEN 243 T+ PSS V+T T P T +T+ PSS LG + TP PN A Sbjct: 2699 TITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPP-VPNTTATT 2757 Query: 244 SAAVQINLSPTMLENVK 260 +LSP+ V+ Sbjct: 2758 HGR---SLSPSSPHTVR 2771 Score = 45.4 bits (106), Expect = 2e-04 Identities = 136/626 (21%), Positives = 204/626 (32%), Gaps = 106/626 (16%) Query: 9 AGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGT 68 A PP + T T A + S+P G P S PT S+ L SP T Sbjct: 1610 ATTPPPTTELETATTTTTQALFSTPQPTSSP---GLTRAPPASTTAVPTLSEGLTSPRYT 1666 Query: 69 LVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLML 128 A + GP PA P T P LP T G L Sbjct: 1667 STLGTA-------TTGGPTTPAGSTEPT-VPGVATSTLPTRSALPGTT-------GSLGT 1711 Query: 129 VSPQQTVTRAETT-SNITSRP---AVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQI 184 P Q T A TT + +RP A A+ + + P +S+L A T + Sbjct: 1712 WRPSQPPTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETT 1771 Query: 185 GTTVVTTVPKPSSVQ-----------SVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTP 233 + + T + + V PTS V G + T ++ + G Sbjct: 1772 MSPLTNTTTSQGTTRCQPKCEWTEWFDVDFPTSGVA---GGDMETFENIRAAG-GKMCWA 1827 Query: 234 SNEPNLKAENSAAVQIN----LSPTMLENVKKCKN----------FLAMLIKLAC----- 274 +AEN V I+ + LE CKN F + L C Sbjct: 1828 PKSIECRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSH 1887 Query: 275 -------SGSQSPEMGQNVKKLVEQLLDAKIEAEEF--TRKLYVELKSSPQPHLVPFLKK 325 S + +P ++ + T L+++P P ++ Sbjct: 1888 CPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTAT 1947 Query: 326 S-VVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSG 384 + V + P+S T++ + T T T+ VT SSS +S Sbjct: 1948 TPTVTSSKATPSSSP-------GTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQ 2000 Query: 385 ATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAATGGTTAGT---GLLQTSKPLVTSV 441 T P T ++ T P + P A V + T ATG + G T+K T+ Sbjct: 2001 TTTP-TATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTT 2059 Query: 442 ANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIG 501 T S P GTA+T P V T+ +V P S GTT V+ Sbjct: 2060 TGFTATPSSSP------GTALT---PPVWISTTTTPTTRGSTVTPS-SIPGTTHTATVLT 2109 Query: 502 TPVQI----KLAQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKC 557 T +A P +Q +G P ++ TTI+ + + T Sbjct: 2110 TTTTTVATGSMATPSSS-TQTSGTPPSLTTT--------------ATTITATGSTTNPSS 2154 Query: 558 GQKTMPVNTIIPTSQFPPASILKQIT 583 T P+ ++ T+ PA+ +T Sbjct: 2155 TPGTTPIPPVLTTTATTPAATSNTVT 2180 Score = 45.4 bits (106), Expect = 2e-04 Identities = 124/583 (21%), Positives = 192/583 (32%), Gaps = 92/583 (15%) Query: 2 PAGLTEPAGAAPPAAVSASGTVTMAP--AGALPVRVESTPVALGAVTKAPVSVCVEPTAS 59 PAG TEP P A S T + P G+L S P L T A TAS Sbjct: 1680 PAGSTEP--TVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSRARPTGTAS 1737 Query: 60 QPLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAP--NTTTIQFPANLQ------ 111 + P L T +AP +S P+ +P NTTT Q Q Sbjct: 1738 TASKEP---LTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQPKCEWT 1794 Query: 112 -----------LPPGTVLIKSN---SGPLMLVSPQQTVTRAETTSNI------------- 144 + G + N +G M +P+ RAE + Sbjct: 1795 EWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQVLTCSL 1854 Query: 145 -----------TSRPAVPANPQTVKIC--------TVPNSSSQLIKKVAVTPVKKLAQIG 185 T R + N +C + P +SS L + Sbjct: 1855 ETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTTWILTKPT 1914 Query: 186 TTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPN------- 238 TT TT +S S A PTS + P + T T P+ + +TPS+ P Sbjct: 1915 TTATTT----ASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPA 1970 Query: 239 LKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKI 298 L++ + +++P ++ L+ + S + +L A Sbjct: 1971 LRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATA 2030 Query: 299 EAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCT 358 T + + H + +S S+ T Sbjct: 2031 TTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRG 2090 Query: 359 TTVTTS--PVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVG 416 +TVT S P T T + + + + +G+ A + S QT P T+ + G Sbjct: 2091 STVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGT---PPSLTTTATTITATG 2147 Query: 417 PT---AATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGE 473 T ++T GTT +L T+ + +NTVT S GT T +P T Sbjct: 2148 STTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSS-------ALGTTHTPPVPN-TMAT 2199 Query: 474 TSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLS 516 T G ++ PS V +A T++ ++GT + +P V S Sbjct: 2200 THGRSL-PPSSPHTVRTAWTSATSGILGT---THITEPSTVTS 2238 Score = 45.1 bits (105), Expect = 3e-04 Identities = 109/517 (21%), Positives = 172/517 (33%), Gaps = 77/517 (14%) Query: 3 AGLTEPAGA-APPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQP 61 A TE G+ A P++ + + P+ V V + A + T+A P S Sbjct: 3703 ATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGT---PHVSTT 3759 Query: 62 LRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKS 121 +P T +K P S+P ++ P L + A T F A I S Sbjct: 3760 ATTPTVTS-SKATPFSSPGTATALPALRST------ATTPTATSFTA----------IPS 3802 Query: 122 NSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKL 181 +S QT T T S T + P T + T ++++ VA TP Sbjct: 3803 SSLGTTWTRLSQTTTPTATMSTATPS-STPETAHTSTVLTTTATTTRATGSVA-TPS--- 3857 Query: 182 AQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLKA 241 + GT T VP ++ P+S P+ TT P++ G++ TPS+ P Sbjct: 3858 STPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPG--- 3914 Query: 242 ENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAE 301 +PT+L +A +P L+ Sbjct: 3915 -------TTHTPTVLTTT---------TTTVATGSMATPSSSTQTSGTPPSLIT------ 3952 Query: 302 EFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTV 361 T S+ P P +P + TSS + ++ T Sbjct: 3953 --TATTITATGSTTNPSSTPGTTP--------IPPVLTTTATTPAATSSTVTPSSALGTT 4002 Query: 362 TTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAAT 421 T PV TT ++ S ++P TV + +G +G T H P+ T Sbjct: 4003 HTPPVPNTTATTHGRSLS-----PSSPHTVRTAWTSATSGTLG------TTHITEPSTGT 4051 Query: 422 GGTTAG-TGLLQTSKPLVTSVANTVTTVSLQPEKPVVS--GTAVTLSLPAVTFGETSGAA 478 T A TG Q S P ++S + T P + T T A + + Sbjct: 4052 SHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTS 4111 Query: 479 ICLPS--VKPVVSSAGTTSDKPVIGTPVQIKLAQPGP 513 LPS +++ TT +P + + P P Sbjct: 4112 TLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMP 4148 Score = 44.7 bits (104), Expect = 4e-04 Identities = 95/449 (21%), Positives = 156/449 (34%), Gaps = 56/449 (12%) Query: 27 PAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTLVTKVAPVSAPPKV---- 82 PA + STP +TK P + ++ +P TL T + PPKV Sbjct: 1892 PATSSTATPSSTPGTTWILTK-PTTTATTTASTGSTATPTSTLRT-----APPPKVLTTT 1945 Query: 83 SSGPRLPAPQIVAVKAPNTTT----IQFPANLQLPPGTVLIKSNSGPLMLVSPQQTVTRA 138 ++ P + + + +P T T ++ A I S+S QT T Sbjct: 1946 ATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPT 2005 Query: 139 ETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSV 198 T S T + P T + T +++ VA TP + GT T VP ++ Sbjct: 2006 ATMSTATPS-STPETAHTSTVLTATATTTGATGSVA-TPS---STPGTAHTTKVPTTTTT 2060 Query: 199 QSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLKAENSAAVQINLSPTM--- 255 A P+S P+ TT P++ G++ TPS+ P ++A V + T+ Sbjct: 2061 GFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPG--TTHTATVLTTTTTTVATG 2118 Query: 256 --------LENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRKL 307 + + + +GS + + +L T Sbjct: 2119 SMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNT 2178 Query: 308 YVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVV 367 + H P +PN+ + SS + T T+ T+ + Sbjct: 2179 VTPSSALGTTHTPP------------VPNTMATTHGRSLPPSSPHTVRTAWTSATSGILG 2226 Query: 368 TTTVSSSQSEKSIIVSGATAPRTVSVQTLNP-LAGPVGAKAGVVTLHSVGPTAATGGTTA 426 TT + +E S + S A T + Q P L+ P + + S G T G TTA Sbjct: 2227 TTHI----TEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPG-TTTPGHTTA 2281 Query: 427 GTGLLQTSKPLVTSVANTVTTVSLQPEKP 455 TS+ T+ + T +L P P Sbjct: 2282 ------TSRTTATATPSKTRTSTLLPSSP 2304 Score = 42.0 bits (97), Expect = 0.002 Identities = 92/415 (22%), Positives = 132/415 (31%), Gaps = 56/415 (13%) Query: 114 PGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKV 173 P T S + P +T+ TT+ T+ A P T + T P +++ Sbjct: 1889 PSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATP-TSTLRTAP--PPKVLTTT 1945 Query: 174 AVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNT-VTTLKPSSLGASST 232 A TP TV ++ PSS A + T P T VT + SSLG + T Sbjct: 1946 ATTP---------TVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWT 1996 Query: 233 PSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGS-----QSPEMGQNVK 287 ++ + + +P E A +GS +P K Sbjct: 1997 RLSQTTTPTATMSTATPSSTP---ETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTK 2053 Query: 288 KLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQ 347 T SSP L P + S S Sbjct: 2054 VPTTT-----------TTGFTATPSSSPGTALTPPVWISTTTT-PTTRGSTVTPSSIPGT 2101 Query: 348 TSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGP-VGAK 406 T + V+ T TTTV T + T + S+ S ++ T + T NP + P Sbjct: 2102 THTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPI 2161 Query: 407 AGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKP----------- 455 V+T + P A + T + L T P V + T SL P P Sbjct: 2162 PPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSAT 2221 Query: 456 --------VVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGT 502 + + VT A T G T + L S P S+ TT P GT Sbjct: 2222 SGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHP---SSRTTESPPSPGT 2273 Score = 42.0 bits (97), Expect = 0.002 Identities = 131/642 (20%), Positives = 213/642 (33%), Gaps = 87/642 (13%) Query: 2 PAGLTEPAGAAPPAAVSASGTVTMAPAGALPVRVESTP-----VALGAVTKAPVSVCVEP 56 P+ T+ +G PP+ + + T+T + P T + A T A S V P Sbjct: 3380 PSSSTQTSGT-PPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTP 3438 Query: 57 ------TASQPLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVA---VKAPNTTTIQFP 107 T + P+ + T + P S+P V + I+ + P+T T P Sbjct: 3439 SSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTP 3498 Query: 108 ANLQLPPGTVLIKSNSGPLM---------LVSPQQTVTRAETTSNITSRPAVPANPQTVK 158 A T +S P + SP T + TSR A P + Sbjct: 3499 A------ATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTR 3552 Query: 159 ICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTP-GKPLN 217 T+ SS P+ TTVVTT +P S + S P G + Sbjct: 3553 TSTLLPSSP------TSAPI-------TTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFD 3599 Query: 218 TVTTLKPSS-------LGASSTPSNEPNLKA-ENSAAVQINLSPTML----ENVKKCKNF 265 T + ++ + LG +P + E V+ +L ++ E V K K Sbjct: 3600 TYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMC 3659 Query: 266 LAMLIKLAC------------SGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRKLYVELKS 313 I++ C S + +P ++ +L E Sbjct: 3660 FNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTA----TP 3715 Query: 314 SPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSS 373 S P L + +P + Q T+ ++T TT T + T SS Sbjct: 3716 SSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSS 3775 Query: 374 SQSEKSI--IVSGATAPRTVSVQTL-NPLAGPVGAKAGVVTLHSVGPTAATGGTTAGTGL 430 + ++ + S AT P S + + G + T + + AT +T T Sbjct: 3776 PGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETA- 3834 Query: 431 LQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVT---FGETSGAAICLPSVKPV 487 TS L T+ T T S+ GTA T +P T F T ++ PV Sbjct: 3835 -HTSTVLTTTATTTRATGSVATPSST-PGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPV 3892 Query: 488 ---VSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNEKQVT 544 ++ TTS V + V P + + + Q SG +T Sbjct: 3893 WISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLIT 3952 Query: 545 T---ISHSSTLTIQKCGQKTMPVNTIIPTSQFPPASILKQIT 583 T I+ + + T T P+ ++ T+ PA+ +T Sbjct: 3953 TATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVT 3994 Score = 40.8 bits (94), Expect = 0.005 Identities = 57/245 (23%), Positives = 88/245 (35%), Gaps = 37/245 (15%) Query: 348 TSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKA 407 T++ + T T T+ T SSS +S T P T ++ T P + P Sbjct: 2521 TATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTP-TATMSTATPSSTPETVHT 2579 Query: 408 GVVTLHSVGPTAATGGTTAGT---GLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTL 464 V + T ATG + G T+K L T+ T S P GTA TL Sbjct: 2580 STVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSP------GTARTL 2633 Query: 465 S--LPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQI----KLAQPGPVLSQP 518 + T T G+ + S+ GTT V+ T +A P +Q Sbjct: 2634 PVWISTTTTPTTRGSTVTPSSI------PGTTHTPTVLTTTTTTVATGSMATPSS-STQT 2686 Query: 519 AGIPQAVQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKTMPVNTIIPTSQFPPASI 578 +G P ++ TTI+ + + T T P+ ++ T+ PA+ Sbjct: 2687 SGTPPSLTT--------------TATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAAT 2732 Query: 579 LKQIT 583 +T Sbjct: 2733 SSTVT 2737 Score = 37.7 bits (86), Expect = 0.046 Identities = 45/220 (20%), Positives = 77/220 (35%), Gaps = 8/220 (3%) Query: 16 AVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTLVTKVAP 75 A + T ++A + P +T V T + P ++ L + T T Sbjct: 2587 ATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTR 2646 Query: 76 VSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLVSPQQTV 135 S S P ++ TTT ++ P + +++ P L + T+ Sbjct: 2647 GSTVTPSSIPGTTHTPTVLTT----TTTTVATGSMATPSSST--QTSGTPPSLTTTATTI 2700 Query: 136 TRAETTSNITSRPAV-PANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPK 194 T +T+N +S P P P T P ++S + + + T TT + Sbjct: 2701 TATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGR 2760 Query: 195 PSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPS 234 S S + T L T +PS+ G S TP+ Sbjct: 2761 SLSPSSPHTVRTAWTSATSGTLGTTHITEPST-GTSHTPA 2799 >gi|38788274 bromodomain PHD finger transcription factor isoform 1 [Homo sapiens] Length = 2920 Score = 63.5 bits (153), Expect = 8e-10 Identities = 164/748 (21%), Positives = 269/748 (35%), Gaps = 128/748 (17%) Query: 73 VAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIK--SNSGPLMLVS 130 VAP+S V++G ++ V +P T T Q N T + + SNSG +V Sbjct: 1951 VAPISG--SVTTGTKMVLT--TKVGSPATVTFQQNKNFHQTFATWVKQGQSNSG---VVQ 2003 Query: 131 PQQTVTRAETTSNITSRPAVPA-NPQTVKICTVPNSS--------SQLIKKVAVTPVKKL 181 QQ V +S TS+ + P+T + PN+S SQ+I + P Sbjct: 2004 VQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRP---- 2059 Query: 182 AQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTL-----KPSSLGASSTPSNE 236 G TV+ T P S A+ + V V PG P +T + +++ A +T S+ Sbjct: 2060 ---GMTVIRT-PLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSST 2115 Query: 237 PNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDA 296 P K+ SA N+ S SQ P Q KL L Sbjct: 2116 PGQKSLTSATSTSNIQS---------------------SASQPPRPQQGQVKLTMAQLTQ 2154 Query: 297 KIEAEEFTRKLYVELKSSPQPH-LVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIA 355 + + L V ++ Q + + + V L P Q T + Sbjct: 2155 LTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPG--PGQQLMQAAMPNGTVQRFLFT 2212 Query: 356 TCTTTVTTSPVVTTTVSSS------------------QSEKSI--IVSGATAPRTVSVQT 395 TT TT+ TTTVS++ +K++ S + P QT Sbjct: 2213 PLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQT 2272 Query: 396 LNPLAGP---VGAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQP 452 P A P ++ P T TT + + ++P + QP Sbjct: 2273 AQPSAQPQPQTQPQSPAQPEVQTQPEVQT-QTTVSSHVPSEAQPTHAQSSKPQVAAQSQP 2331 Query: 453 EKPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPG 512 + V + V + P+ T S + P + S TT+ +P+ P+Q + Sbjct: 2332 QSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQ---SQVQTTTSQPI---PIQPHTSLQI 2385 Query: 513 PVLSQPAGIPQAVQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKTMPVNTIIPTSQ 572 P QP PQ Q Q S G T+S S +Q Q+ P +P Q Sbjct: 2386 PSQGQPQSQPQV----QSSTQTLSSGQTLNQVTVSSPSRPQLQI--QQPQPQVIAVPQLQ 2439 Query: 573 FPPASILKQI-TLPGNKILSLQASPTQKNRIKENV---TSCFRDEDDINDVTSMAGVNLN 628 +L QI + +I + Q+ Q+ +++ + S I +V ++ ++ Sbjct: 2440 -QQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQ 2498 Query: 629 EENACILATNSELVGTLIQSCKDEPFLFIGALQKRILDIGKKHDITELNSDAVNLISQAT 688 E+ +Q +D+ +K+ I K + T S+ +I + Sbjct: 2499 EQL------------QRVQQLRDQ------QQKKKQQQIEIKREHTLQASNQSEIIQKQV 2540 Query: 689 QERLRGLLEKLTAIAQHRMTTYKASENYILCSDTRSQLKFLEKLDQLEKQRKDLEEREML 748 + ++E L + ++ I+C+ + L+K+D+ EKQ Sbjct: 2541 VMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYI--LDKIDKEEKQ---------- 2588 Query: 749 LKAAKSRSNKEDPEQLRLKQKAKELQQL 776 AAK R +E EQ R KQ A +L L Sbjct: 2589 --AAKKRKREESVEQKRSKQNATKLSAL 2614 Score = 38.9 bits (89), Expect = 0.021 Identities = 56/224 (25%), Positives = 92/224 (41%), Gaps = 44/224 (19%) Query: 353 VIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVV-- 410 VIAT TT+ T+S T+T+S +Q +SG+ T V T VG+ A V Sbjct: 1927 VIATSTTSPTSS--TTSTISPAQKVMVAPISGSVTTGTKMVLTTK-----VGSPATVTFQ 1979 Query: 411 ---TLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTV-----TTVSLQPE------KPV 456 H T G + +G++Q + ++ + ++ T S QP +P Sbjct: 1980 QNKNFHQTFATWVKQG-QSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPN 2038 Query: 457 VSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGT-----TSDKPVIGTPVQIKLAQP 511 SG+ T S V G P ++P ++ T T K +I TPV ++ P Sbjct: 2039 TSGSGGTTSNSQVITG---------PQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAP 2089 Query: 512 GPVLSQ---PAGIPQAVQVKQLVVQQPSGGNEKQVTTISHSSTL 552 V++Q + AV V P +K +T+ + +S + Sbjct: 2090 QQVMTQIIRGQPVSTAVSAPNTVSSTP---GQKSLTSATSTSNI 2130 Score = 34.3 bits (77), Expect = 0.51 Identities = 107/517 (20%), Positives = 183/517 (35%), Gaps = 103/517 (19%) Query: 62 LRSPVGTLVTKVAPVSAPPKVSSG-PRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIK 120 +R+P+ A + P V G P+ QI+ + P +T + P + PG Sbjct: 2064 IRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQ-PVSTAVSAPNTVSSTPG----- 2117 Query: 121 SNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKK 180 Q+++T A +TSNI S + P PQ ++ +QL + Sbjct: 2118 -----------QKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHG------ 2160 Query: 181 LAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPG---------KPLNTV-----TTLKPSS 226 G TVV ++ Q +P VTV PG P TV T L ++ Sbjct: 2161 -GNQGLTVVIQGQGQTTGQLQLIPQG-VTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTA 2218 Query: 227 LGASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNV 286 AS+T + A Q LSP M + K +QS +G Sbjct: 2219 TTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDK-----------TLPPAQSSSVG--- 2264 Query: 287 KKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQ 346 EA+ T + + PQP P QS Q VQ Sbjct: 2265 ----------PAEAQPQT----AQPSAQPQPQTQP----------------QSPAQPEVQ 2294 Query: 347 QTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAK 406 TTV++ + +QS K + + + V Q+ + P + Sbjct: 2295 TQPE----VQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTR 2350 Query: 407 AGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSL-QPE-KPVVSGTAVTL 464 T + P + T TS+P+ ++ S QP+ +P V + TL Sbjct: 2351 IRPSTPSQLSPGQQSQVQTT------TSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTL 2404 Query: 465 S----LPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAG 520 S L VT S + + +P V + + + + +Q ++ + +Q +G Sbjct: 2405 SSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVV--AQIQAQQSG 2462 Query: 521 IPQAVQVK-QLVVQQPSGGNEKQVTTISHSSTLTIQK 556 +PQ ++++ + +QQ S Q+ + ++Q+ Sbjct: 2463 VPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQE 2499 >gi|167736355 mucin 4 isoform a [Homo sapiens] Length = 5284 Score = 63.2 bits (152), Expect = 1e-09 Identities = 137/640 (21%), Positives = 229/640 (35%), Gaps = 50/640 (7%) Query: 10 GAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTL 69 G P V+ + + + A +LPV +++ V+ G T P+ V +AS +P+ Sbjct: 1116 GHTTPLPVTDTSSASTGHATSLPV-TDTSSVSTGHTT--PLHVTDASSASTGQATPL--- 1169 Query: 70 VTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLV 129 PV++ VS+G P P V +P++ + L + + ++ PL + Sbjct: 1170 -----PVTSLSSVSTGDTTPLP----VTSPSSASTGHATPLLVTDTSSASTGHATPLPVT 1220 Query: 130 SPQQTVTRAETTSNITSRPAVPANPQT-VKICTVPNSSSQLIKKVAVTPVKKLAQIGTTV 188 T T+ +T A T + + ++S+ + VT ++ G T Sbjct: 1221 DASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVST-GDTT 1279 Query: 189 VTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLKAENSAAVQ 248 V SS + V VT T L +SL ++ST P S+A Sbjct: 1280 PLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSAST 1339 Query: 249 INLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRKLY 308 + +P + + L + + S GQ V L + + + T Sbjct: 1340 GDTTPLPVTDASSVST--GHTTPLHVTDASSASTGQATPLPVTSL--SSVSTGDTTPLPV 1395 Query: 309 VELKSSPQPHLVPFL----KKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTS 364 S+ H P L + LP + + TS + I + +T T+ Sbjct: 1396 TSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTT 1455 Query: 365 PV-VTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAATGG 423 P+ VT T S+S + + ++ T +VS PL PV + + T H V P T Sbjct: 1456 PLPVTDTSSASTGQATSLL--VTDTSSVSTGDTTPL--PVTSTSSASTGH-VTPLHVTSP 1510 Query: 424 TTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETS-GAAICLP 482 ++A TG S A+T T+ L P + T T LP S G LP Sbjct: 1511 SSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLP 1570 Query: 483 SVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAV---QVKQLVVQQPSGGN 539 P +S G T+ PV T A G P P + L V S + Sbjct: 1571 VTSPSSASTGHTTPLPVTDT----SSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSAS 1626 Query: 540 EKQVTTI----------SHSSTLTIQKCGQKTMPVNTIIPTSQFPPASILKQITLPGNKI 589 T + H++ L + + T +P + AS LP + Sbjct: 1627 TGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVTGL 1686 Query: 590 LSLQASPTQKNRIKENVTSCFRDEDDINDVTSMAGVNLNE 629 S T + + + V+S + VTS++ V+ + Sbjct: 1687 SSATTDDTTRLPVTD-VSSASTGQATPLPVTSLSSVSTGD 1725 Score = 56.6 bits (135), Expect = 1e-07 Identities = 135/585 (23%), Positives = 209/585 (35%), Gaps = 81/585 (13%) Query: 10 GAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTL 69 G A P V++ + + A LPV +++ + G T PV+ S V T Sbjct: 2924 GHANPLHVTSPSSASTGHATPLPV-TDTSSASTGHATPLPVTSL----------SSVSTG 2972 Query: 70 VTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLV 129 T PV++P S+G P P A P T ++ PL + Sbjct: 2973 DTTPLPVTSPSSASTGHTTPLPVTDTSSASTGQATALPVTSTSSAST----GDTTPLPVT 3028 Query: 130 SPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVV 189 T T +TS +V T T P+S+S TP+ +V Sbjct: 3029 DTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSAS----TGHATPL---------LV 3075 Query: 190 TTVPKPSSVQSVAVP-TSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLKAENSAAVQ 248 T S+ Q+ +P TS+ +V+ G TT P + +S++ + +L ++++ Sbjct: 3076 TDASSASTGQATPLPVTSLSSVSTGD-----TTPLPVTSPSSASTGHATSLPVTDTSSAS 3130 Query: 249 INLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRKLY 308 T L + L + + S G LV + + + T L Sbjct: 3131 TG-DTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLVTE--TSSVSTGHATPLLV 3187 Query: 309 VELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTT---SP 365 + S+ H P L P+S S + V T T++V+T +P Sbjct: 3188 TDASSASTGHATP--------LHVTSPSSAS-------TGDTTPVPVTDTSSVSTGHATP 3232 Query: 366 VVTTTVSSSQ---------SEKSIIVSGATAP----RTVSVQTLNPLAGPVGAKAGVVTL 412 + T +SS+ ++ S +G P T SV T + + PV + + T Sbjct: 3233 LPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTMPLPVTSPSSASTG 3292 Query: 413 HSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFG 472 H+ P T ++A TG TS A+T T L + T T LP + Sbjct: 3293 HAT-PLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSASTGDTTPLPVTSPS 3351 Query: 473 ETS-GAAICLPSVKPVVSSAGTTSDKPVIG-TPVQIKLAQPGPVL---SQPAGIPQAVQV 527 S G L P +S G TS PV G + A P PV S G + V Sbjct: 3352 SASTGHTTPLHVTIPSSASTGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPV 3411 Query: 528 KQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKT-MPVNTIIPTS 571 L VT S +ST GQ T +PV ++ S Sbjct: 3412 TSLSSVSTGDTTPLPVTDASSAST------GQATPLPVTSLSSVS 3450 Score = 55.8 bits (133), Expect = 2e-07 Identities = 131/587 (22%), Positives = 209/587 (35%), Gaps = 49/587 (8%) Query: 2 PAGLTEPAGA----APPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPT 57 P +T P+ A A P V++ + + LPV S+ + G T PV+ Sbjct: 1504 PLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSS-ASTGDTTPLPVTDA---- 1558 Query: 58 ASQPLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTV 117 S V T T PV++P S+G P P A T P T Sbjct: 1559 ------SSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSAST- 1611 Query: 118 LIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTP 177 ++ PL + T T +T+ ++ T T P+S+S P Sbjct: 1612 ---GHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSAS--TGHATPLP 1666 Query: 178 VKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNT--VTTLKPSSLGASSTPSN 235 V + T T +P + T+ + VT +T T L +SL + ST Sbjct: 1667 VTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDT 1726 Query: 236 EPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLD 295 P S+A + SP ++ + A + + + S S + V L Sbjct: 1727 TPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDTSSVSTAHATPLP--VTGLSS 1784 Query: 296 AKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVAL----RQLLPNSQSFIQQCVQQTSSD 351 A ++ TR ++ S+ +P S + LP + + TS Sbjct: 1785 A--STDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDTTSLP 1842 Query: 352 MVIATCTTT--VTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGV 409 + I + ++ T+ PV + S+ S++V+ A++ T L P+ A G Sbjct: 1843 VTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTPL-PVTDTNSASTGD 1901 Query: 410 VTLHSVGPTAATGGTTAGTGLLQTSKPLVT-SVANTVTTVSLQPEKPVVSGTAVTLSLPA 468 T P T ++ TG TS P+ + S A+T T L P + + T LP Sbjct: 1902 TT-----PLHVTDASSVSTG-HATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPV 1955 Query: 469 VTFGET-SGAAICLPSVKPVVSSAGTTSDKPVI-GTPVQIKLAQPGPVL-SQPAGIPQAV 525 +G A LP S G + PV + V A P PV + QA Sbjct: 1956 TDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQAT 2015 Query: 526 QVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKT-MPVNTIIPTS 571 + + S G+ + SS T GQ T +PV ++ S Sbjct: 2016 PLPVTSLSSASTGDTTPLPVTDTSSAST----GQDTPLPVTSLSSVS 2058 Score = 54.7 bits (130), Expect = 4e-07 Identities = 141/644 (21%), Positives = 225/644 (34%), Gaps = 116/644 (18%) Query: 2 PAGLTEPAGAAP----PAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPT 57 P +T P+ A+ P V+ + +V+ A LPV S+ + G T+ PV+ + Sbjct: 3200 PLHVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSS-ASTGDTTRLPVTDISSAS 3258 Query: 58 ASQ--PL----RSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIV--------AVKAPNTTT 103 Q PL S V T T PV++P S+G P P A P T+T Sbjct: 3259 TGQATPLPVTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTST 3318 Query: 104 IQFPANLQLP-PGTVLIKSNSG---PLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKI 159 P P T +++G PL + SP T T ++T +P++ T Sbjct: 3319 SSASTGHTTPLPVTDTSSASTGDTTPLPVTSPSSASTGHTTPLHVT----IPSSASTGDT 3374 Query: 160 CTVP--NSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLN 217 T+P +SS PV + + T T +P S T+ + VT + Sbjct: 3375 STLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSAS 3434 Query: 218 T--VTTLKPSSLGASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACS 275 T T L +SL + ST P L + S+ + +P + + +L + Sbjct: 3435 TGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSAST--GDTTRLPVT 3492 Query: 276 GSQSPEMGQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPF------------- 322 + S GQ V L + + + T L + S H P Sbjct: 3493 DTSSASTGQATPLPVTSL--SSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDT 3550 Query: 323 -----------LKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTT----------- 360 L +P+S S +S ++T T Sbjct: 3551 TRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSAS 3610 Query: 361 ---VTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLN---------------PLAGP 402 VT PV +T+ +S+ ++V+ A++ T L P+ Sbjct: 3611 TGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDT 3670 Query: 403 VGAKAG------VVTLHSVG-----PTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQ 451 A G V +L SV P T ++A TG + PL ++ ++V+T Sbjct: 3671 SSASTGQATPLPVTSLSSVSTGDTTPLPVTDASSASTG---HATPLPVTIPSSVSTGDTM 3727 Query: 452 PEKPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGT-PVQIKLAQ 510 P PV S ++ ++G A LP +S G T+ PV T + A Sbjct: 3728 P-LPVTSPSSA-----------STGHATPLPVTGLSSASTGDTTPLPVTDTSSASTRHAT 3775 Query: 511 PGPVL-SQPAGIPQAVQVKQLVVQQPSGGNEKQVTTISHSSTLT 553 P PV + A ++ V S G+ + S SS T Sbjct: 3776 PLPVTDTSSASTDDTTRLPVTDVSSASTGHATPLPVTSTSSAST 3819 Score = 53.9 bits (128), Expect = 6e-07 Identities = 123/546 (22%), Positives = 192/546 (35%), Gaps = 62/546 (11%) Query: 2 PAGLTEPAGA----APPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPT 57 P +T P+ A A P V+ + + + A LPV +++ V+ T PV+ + Sbjct: 1728 PLPVTSPSSASTGHASPLLVTDASSASTGQATPLPV-TDTSSVSTAHATPLPVTGLSSAS 1786 Query: 58 ASQPLRSPVGTLVTKVA------PVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQ 111 R PV + + PV++P S+G P P A A T P + Sbjct: 1787 TDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDTTSLP--VT 1844 Query: 112 LPPGTVLIKSNSGPLMLVSPQQT-------VTRAE--TTSNITSRPAVPANPQTVKICT- 161 +P + S P+ S T VT A +T + T P N + T Sbjct: 1845 IPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTDTNSASTGDTTP 1904 Query: 162 --VPNSSSQLIKKVAVTPVKKL--AQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLN 217 V ++SS PV L A G T V PSS S VT P Sbjct: 1905 LHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTG 1964 Query: 218 TVTTLKPSSLGASSTPSNEPNLKAENSA-----AVQINLSPTMLENVKKCKNFLAMLIKL 272 T+L + + ST P + S+ A + ++ T + + + Sbjct: 1965 HATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSS 2024 Query: 273 ACSGSQSP---------EMGQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFL 323 A +G +P GQ+ V L + + + T S+ H P L Sbjct: 2025 ASTGDTTPLPVTDTSSASTGQDTPLPVTSL--SSVSTGDTTPLPVTSPSSASTGHATPLL 2082 Query: 324 KKSVVAL-----RQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEK 378 ++ LL S + T+ + A+ +T T+P+ T+ SS+ Sbjct: 2083 VTDASSVSTGHATSLLVTDASSV-STGHATALHVTDASSLSTGDTTPLPVTSPSSAS--- 2138 Query: 379 SIIVSGATAP----RTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAATGGTTAGTGLLQTS 434 +G T P T SV T + + PV + T H+ T ++A TG Sbjct: 2139 ----TGDTTPLPVTDTSSVSTGHATSLPVTDTSSASTGHATS-LPVTDTSSASTGHATPL 2193 Query: 435 KPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAV-TFGETSGAAICLPSVKPVVSSAGT 493 TS A+T L P + T + L T ++G A LP +S G Sbjct: 2194 PVTDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGD 2253 Query: 494 TSDKPV 499 T+ PV Sbjct: 2254 TTPLPV 2259 Score = 51.2 bits (121), Expect = 4e-06 Identities = 133/614 (21%), Positives = 211/614 (34%), Gaps = 75/614 (12%) Query: 9 AGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPV----SVCVEPTASQPLRS 64 +G P V+ + +V+ A +LPV +++ V+ G T PV SV PL S Sbjct: 2715 SGHTTPLPVTDASSVSTGHATSLPV-TDASSVSTGHATPLPVTDASSVSTGHATPLPLTS 2773 Query: 65 --PVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSN 122 V T T PV+ S+G P P T++ + P V S+ Sbjct: 2774 LSSVSTGDTTPLPVTDTSSASTGQATPLP---------VTSLSSVSTGDTTPLPVTDTSS 2824 Query: 123 SGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICT---VPNSSSQLIKKVAVTPVK 179 + S T T + +T + T P + + T V ++SS I PV Sbjct: 2825 ASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIGHATSLPVT 2884 Query: 180 KLAQIGTTVVTT--VPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEP 237 + I T T V PSS + VT T L +S ++ST P Sbjct: 2885 DTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLHVTSPSSASTGHATP 2944 Query: 238 NLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAK 297 + S+A + +P + ++ L + S G V A Sbjct: 2945 LPVTDTSSASTGHATPLPVTSLSSVST--GDTTPLPVTSPSSASTGHTTPLPVTDTSSA- 3001 Query: 298 IEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQL--LPNSQSFIQQCVQQTSSDMVIA 355 S+ Q +P S + LP + + Q T + Sbjct: 3002 ---------------STGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVTSL 3046 Query: 356 TCTTTVTTSPVVTTTVSSSQSEKS--IIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLH 413 + +T T+P+ T+ SS+ + + ++V+ A++ T L PV + + V T Sbjct: 3047 SSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPL-----PVTSLSSVSTGD 3101 Query: 414 SVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGE 473 + P T ++A TG + TS A+T T SL + T T SLP + Sbjct: 3102 TT-PLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVT---D 3157 Query: 474 TSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQ 533 TS SS G T+ V T + P+L A L V Sbjct: 3158 TSS------------SSTGDTTPLLVTETS-SVSTGHATPLLVTDASSASTGHATPLHVT 3204 Query: 534 QPSGGNEKQVTTISHSSTLTIQKCGQKTMPV----------NTIIPTSQFPPASILKQIT 583 PS + T + + T ++ +PV T +P + AS + Sbjct: 3205 SPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATP 3264 Query: 584 LPGNKILSLQASPT 597 LP S+ T Sbjct: 3265 LPVTNTSSVSTGDT 3278 Score = 43.9 bits (102), Expect = 6e-04 Identities = 109/527 (20%), Positives = 179/527 (33%), Gaps = 90/527 (17%) Query: 10 GAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTL 69 G A P V++ +V+ LPV +++ + G T PV++ S V T Sbjct: 3676 GQATPLPVTSLSSVSTGDTTPLPV-TDASSASTGHATPLPVTI----------PSSVSTG 3724 Query: 70 VTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLV 129 T PV++P S+G P P A T P T ++ PL + Sbjct: 3725 DTMPLPVTSPSSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSAST----RHATPLPV- 3779 Query: 130 SPQQTVTRAETTSNITSRPAVPANPQTVKICT---VPNSSSQLIKKVAVTPVKKLAQIGT 186 T T + +T + T P + + T V ++SS PV + + T Sbjct: 3780 ----TDTSSASTDDTTRLPVTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVST 3835 Query: 187 TVVTTVP---KPSSVQSVAVP-----TSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPN 238 T++P + S+ A P TS V+ PL +T S+ A+ P P+ Sbjct: 3836 GHATSLPVTSRSSASTGHATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSPS 3895 Query: 239 LKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKI 298 A A + ++ T A +G +P N L Sbjct: 3896 -SASTGHATPVPVTST----------------SSASTGDTTPLPVTNASSL--------- 3929 Query: 299 EAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCT 358 + L+V SS LP + + T + + Sbjct: 3930 -STGHATPLHVTSPSSASR-----------GDTSTLPVTDASSASTGHATPLPLTSLSSV 3977 Query: 359 TTVTTSPVVTTTVSSSQSEK---------SIIVSGATAPRTVSVQTL----NPLAGPVGA 405 +T T+P+ T SS+ + + S + +G T P V++ + + + PV Sbjct: 3978 STGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTD 4037 Query: 406 KAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLS 465 + V T H P T ++A TG TS A+T L + T Sbjct: 4038 ASSVSTGHGT-PLPVTSTSSASTGDTTPLPVTDTSSASTGHATPLPVTDTSSASTGHATP 4096 Query: 466 LPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPG 512 LP + S +V S++ +SD P +K+ PG Sbjct: 4097 LPVTSLSSVSTGHATPLAVSSATSASTVSSDSP-------LKMETPG 4136 Score = 43.5 bits (101), Expect = 8e-04 Identities = 114/533 (21%), Positives = 192/533 (36%), Gaps = 63/533 (11%) Query: 8 PAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVG 67 P G + P + SAS T A + + + T + G+ T + S + ++ P P Sbjct: 885 PTGQSSPTSPSASPQETAAISRM--AQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSI 942 Query: 68 TLVTKVAPVSAPPKVS---SGPRLPAPQI-----VAVKAPNTTTIQFPANLQLPPGTVLI 119 T +P + +S SG I + V ++ + L + + + Sbjct: 943 TSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYASSASTGHTTPLHVTDASSVS 1002 Query: 120 KSNSGPLMLVSPQQ-----------TVTRAETTSNITSRPAVPANPQTVKICT---VPNS 165 ++ PL + SP T T +E+T ++T P + + T V ++ Sbjct: 1003 TGHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLPVTDT 1062 Query: 166 SSQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTV-TTLKP 224 SS V PV L+ T T +P + + + + VT ++T TT P Sbjct: 1063 SSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLP 1122 Query: 225 SSLGASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQ 284 + +S++ + +L ++++V + T L L + S G Sbjct: 1123 VTDTSSASTGHATSLPVTDTSSVSTGHT-TPLHVTDASSASTGQATPLPVTSLSSVSTGD 1181 Query: 285 NVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQC 344 V A T L + S+ H P LP + + Sbjct: 1182 TTPLPVTSPSSAS--TGHATPLLVTDTSSASTGHATP------------LPVTDASSVST 1227 Query: 345 VQQTSSDMVIATCTTTVTTSPV-VTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPV 403 TS + I + +T T+P+ VT T S+S + + ++ T +VS PL PV Sbjct: 1228 DHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLL--VTDTSSVSTGDTTPL--PV 1283 Query: 404 GAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVT 463 + + T H V P T ++A TG S A+T T+ L P + T T Sbjct: 1284 TSTSSASTGH-VTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDT 1342 Query: 464 LSLP-----AVTFGET------------SGAAICLPSVKPVVSSAGTTSDKPV 499 LP +V+ G T +G A LP S G T+ PV Sbjct: 1343 TPLPVTDASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPV 1395 Score = 41.2 bits (95), Expect = 0.004 Identities = 103/485 (21%), Positives = 169/485 (34%), Gaps = 63/485 (12%) Query: 141 TSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQS 200 T ++ + + T +C+V N+S +K+ VT T+ +T+ P S Sbjct: 232 TGTVSQKTSPSGETATSSLCSVTNTSMMTSEKITVT---------TSTGSTLGNPGETSS 282 Query: 201 VAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLKAENSAAVQINLSPTMLENVK 260 V V S++ VT + T P +P+ +++ A N +E + Sbjct: 283 VPVTGSLMPVTSA----ALVTFDPE----GQSPATFSRTSTQDTTAFSKNHQTQSVETTR 334 Query: 261 KCK-NFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHL 319 + N L L + S S G N V Q + E T SSP Sbjct: 335 VSQINTLNTLTPVTTSTVLSSPSGFNPSGTVSQ---ETFPSGETT-------TSSPSSVS 384 Query: 320 VPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDM--VIATCTTTVTT---SPVVTTTVSSS 374 FL S V +P S+ ++TS + I+ T+ V+T S ++T +S S Sbjct: 385 NTFLVTSKVF---RMPTSRDSTLGNTEETSLSVSGTISAITSKVSTIWWSDTLSTALSPS 441 Query: 375 QSEKSIIVSGATAPRTVSVQTLNP---LAGPVGAKAGVVTLHSVGPTAATGGTTAGTGLL 431 I + T + T P + G + TLH ++ + T Sbjct: 442 SLPPKISTAFHTQQSEGAETTGRPHERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWS 501 Query: 432 QTSKP---------LVTSVANTVT--TVSLQPEKPVV---SGTAVTLSLPAVTFGETSGA 477 QT P LVT +T T T+ P K G T S + T +T+GA Sbjct: 502 QTELPSTSTGAATRLVTGNPSTGTAGTIPRVPSKVSAIGEPGEPTTYSSHSTTLPKTTGA 561 Query: 478 AICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQ-VKQLVVQQPS 536 + ++ P IK A + P+ P + Q + PS Sbjct: 562 GAQTQWTQETGTTGEALLSSPSYSVTQMIKTA------TSPSSSPMLDRHTSQQITTAPS 615 Query: 537 GGNEK-QVTTISHSSTLTIQKCGQKTMPVNT--IIPTSQFPPASILKQITLPGNKILSLQ 593 + T+ S + + + G P T T P + K +T PG+ + Sbjct: 616 TNHSTIHSTSTSPQESPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASG 675 Query: 594 ASPTQ 598 SP++ Sbjct: 676 HSPSE 680 Score = 40.0 bits (92), Expect = 0.009 Identities = 126/584 (21%), Positives = 194/584 (33%), Gaps = 73/584 (12%) Query: 2 PAGLTEPAGA----APPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPT 57 P +T P+ A A P V+ + + + A LPV S+ + G T PV+ + Sbjct: 2288 PLPVTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSS-ASTGDTTPLPVTSPSSAS 2346 Query: 58 ASQ--PLR----SPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQ 111 PL S V T T PV++ SSG P P A A T P Sbjct: 2347 TGHATPLHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPV--- 2403 Query: 112 LPPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICT---VPNSSSQ 168 T T + +T + T P + + T V N SS Sbjct: 2404 ----------------------TDTSSASTGHATHLPVTGLSSASTGDTTRLPVTNVSSA 2441 Query: 169 LIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNT--VTTLKPSS 226 PV + T T +P + T+ + VT ++T T L +S Sbjct: 2442 STGHATPLPVTSTSSASTGDTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTS 2501 Query: 227 LGASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNV 286 ++ST P + +A + +P + N A + + S S ++ Sbjct: 2502 PSSASTGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSL 2561 Query: 287 KKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQ 346 + D + L V SS + LP + ++ Q Sbjct: 2562 -----PVTDTSAASTGHATPLPVTSTSS-----------ASTGDTTPLPVTDTYSASTGQ 2605 Query: 347 QTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPL--AGPVG 404 T + + +T T+P+ T SS+ + + + T +VS PL P Sbjct: 2606 ATPLPVTDTSSASTGDTTPLPVTDTSSASTGHATPLP-VTNTSSVSTGHATPLHVTSPSS 2664 Query: 405 AKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVT--TVSLQPEKPVVSGTAV 462 A G T P T ++ TG TS P VT ++ T SL P + + Sbjct: 2665 ASTGHTT-----PLPVTDASSVSTG-HATSLP-VTDASSVFTGHATSLPVTIPSSASSGH 2717 Query: 463 TLSLPAVTFGETS-GAAICLPSVKPVVSSAGTTSDKPVI-GTPVQIKLAQPGPVLSQPAG 520 T LP S G A LP S G + PV + V A P P+ S + Sbjct: 2718 TTPLPVTDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSS- 2776 Query: 521 IPQAVQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKTMPV 564 L V S + Q T + +S ++ +PV Sbjct: 2777 -VSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPV 2819 Score = 38.1 bits (87), Expect = 0.035 Identities = 139/641 (21%), Positives = 225/641 (35%), Gaps = 92/641 (14%) Query: 6 TEPAG---AAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPL 62 T P+G + P++VS + VT + +P +ST LG + +SV +A Sbjct: 369 TFPSGETTTSSPSSVSNTFLVT-SKVFRMPTSRDST---LGNTEETSLSVSGTISAITSK 424 Query: 63 RSPV---GTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLI 119 S + TL T ++P S PPK+S+ + F + T L Sbjct: 425 VSTIWWSDTLSTALSPSSLPPKISTAFHTQQSEGAETTGRPHERSSFSPGVSQEIFT-LH 483 Query: 120 KSNSGPLMLVSPQQTV---TRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVT 176 ++ + P S T T +TS + V NP T T+P S KV+ Sbjct: 484 ETTTWPSSFSSKGHTTWSQTELPSTSTGAATRLVTGNPSTGTAGTIPRVPS----KVSAI 539 Query: 177 PVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNE 236 ++ TT+PK + + T T L++ + + +++PS+ Sbjct: 540 GEPGEPTTYSSHSTTLPKTTGAGAQTQWTQETGTTGEALLSSPSYSVTQMIKTATSPSSS 599 Query: 237 PNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDA 296 P L S QI +P+ + + + S +SP + Q Sbjct: 600 PMLDRHTSQ--QITTAPSTNHST---------IHSTSTSPQESPAVSQR----------G 638 Query: 297 KIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIAT 356 +A + T++ SP K+V S + V Q + + AT Sbjct: 639 HTQAPQTTQESQTTRSVSPMTD-----TKTVTTPGSSFTASGHSPSEIVPQDAPTISAAT 693 Query: 357 CTTT-------VTTSPVVTTTVSSSQSEKSIIVSGATA-PRTVSVQTLNPLAGPVGAKAG 408 T +P + S + ++ SG T+ +T ++ N + G G Sbjct: 694 TFAPAPTGDGHTTQAPTTALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVSTPGGPEG 753 Query: 409 VVTLHSVGPTAATGG---------TTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSG 459 T S + T +T +G QTS+P +S + T + + P SG Sbjct: 754 QWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEP-ASSGSRTTSAGTATPSSSGASG 812 Query: 460 TAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGT-------PVQIKLAQ-- 510 T + S T GET+ S P S T S ++ PV +A Sbjct: 813 TTPSGSEGISTSGETTRF-----SSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSI 867 Query: 511 -PG---PVLSQ------PAG--IPQAVQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCG 558 PG P LS+ P G P + S + Q T S S TI Sbjct: 868 VPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSD-TISLAS 926 Query: 559 QKTMPVNTIIPTSQFPPASILKQITLPGNKILSLQASPTQK 599 Q T +T+ PT PP+ +T P + +L S + K Sbjct: 927 QATDTFSTVPPT---PPSITSTGLTSPQTETHTLSPSGSGK 964 Score = 35.8 bits (81), Expect = 0.18 Identities = 73/318 (22%), Positives = 116/318 (36%), Gaps = 54/318 (16%) Query: 296 AKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIA 355 +K + + T+ + L SSP H V ++ + S + + TS Sbjct: 86 SKAQTDTLTQMMTSTLFSSPSVHNV----METAPPDEMTTSFPSSVTNTLMMTSK----- 136 Query: 356 TCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSV 415 T T+TTS T + + E S + ++ P T +V AG G S+ Sbjct: 137 --TITMTTS---TDSTLGNTEETSTAGTESSTPVTSAVSIT---AGQEGQSRTTSWRTSI 188 Query: 416 GPTAATGGTTAGTGLLQTSKPLVTSVAN--TVTTVSLQPEKPVVSGTAVTLSLPAVTFGE 473 T+A+ T QT++ TS T +T S P V+GT + P+ GE Sbjct: 189 QDTSASS-QNHWTRSTQTTRESQTSTLTHRTTSTPSFSPSVHNVTGTVSQKTSPS---GE 244 Query: 474 TSGAAICLPSVKPVVSSAG---TTSDKPVIGTPVQIKLAQPGPVLSQP-AGIPQAVQVKQ 529 T+ +++C + +++S TTS +G PG S P G V Sbjct: 245 TATSSLCSVTNTSMMTSEKITVTTSTGSTLG--------NPGETSSVPVTGSLMPVTSAA 296 Query: 530 LVVQQPSGGNEKQVTTISHSSTLTIQKCGQ----------KTMPVNTIIPT--------- 570 LV P G + + S T K Q + +NT+ P Sbjct: 297 LVTFDPEGQSPATFSRTSTQDTTAFSKNHQTQSVETTRVSQINTLNTLTPVTTSTVLSSP 356 Query: 571 SQFPPASILKQITLPGNK 588 S F P+ + Q T P + Sbjct: 357 SGFNPSGTVSQETFPSGE 374 Score = 30.4 bits (67), Expect = 7.4 Identities = 39/188 (20%), Positives = 65/188 (34%), Gaps = 20/188 (10%) Query: 10 GAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPV--- 66 G A P V++ +V+ LPV + S+ + G T PV+ + PV Sbjct: 3996 GQATPLPVTSLSSVSTGDTTPLPVTIPSS-ASSGHTTSLPVTDASSVSTGHGTPLPVTST 4054 Query: 67 ---GTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFP----ANLQLPPGTVLI 119 T T PV+ S+G P P A P +++ T L Sbjct: 4055 SSASTGDTTPLPVTDTSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGHATPLA 4114 Query: 120 KSNS---------GPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLI 170 S++ PL + +P T +T + + P I T+P+++ Sbjct: 4115 VSSATSASTVSSDSPLKMETPGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPSTAMHTR 4174 Query: 171 KKVAVTPV 178 A P+ Sbjct: 4175 STAAPIPI 4182 >gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens] Length = 1486 Score = 62.8 bits (151), Expect = 1e-09 Identities = 144/713 (20%), Positives = 254/713 (35%), Gaps = 95/713 (13%) Query: 8 PAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVG 67 P P++VSA+ T + E TP+ G++ T+ P+ + + Sbjct: 199 PIVTVTPSSVSATDTTFHTTISSTTRTTERTPLPTGSIHTT--------TSPTPVFTTLK 250 Query: 68 TLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIK------- 120 T VT +P+++ ++S + + A + T T+ P L VL Sbjct: 251 TAVTSTSPITS--SITSTNTVTSMTTTASQPTATNTLSSPTRTILSSTPVLSTETITSGI 308 Query: 121 SNSGPL--MLVSPQQTVTRAETTSNIT--SRPAVPANPQTVKIC--------------TV 162 +N+ PL ++ + T++R+ TS T + P T KI Sbjct: 309 TNTTPLSTLVTTLPTTISRSTPTSETTYPTSPTSTVTDSTTKIAYSTSMTGTLSTETSLP 368 Query: 163 PNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTL 222 P SSS + A TP+ L TT +++ PS S T TP + TT Sbjct: 369 PTSSSLPTTETATTPMTNLVTT-TTEISSHSTPSFSSSTIYSTVTSHSTPRFTSSITTTE 427 Query: 223 KPSSLGASSTP---SNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQS 279 PS STP S+ N K + + T E I + S S Sbjct: 428 TPSH----STPRFTSSFTNTKTTSHRSPSFTSLITTTETTSHSTPSFTSSITTTETTSHS 483 Query: 280 PEMGQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQS 339 ++ + FT + +S H S+ ++ S Sbjct: 484 ---ARSFTSSITTTETTSHNTRSFTSSITTTETNS---HSTTSFTSSITTTETTSHSTPS 537 Query: 340 FIQQCVQQT----SSDMVIATCTTTVTTSPV-------VTTTVSSSQSEKSIIVSGATAP 388 F S+ + + TTT TTS + +TTT ++S S S T Sbjct: 538 FSSSITTTETPLHSTPGLTSWVTTTKTTSHITPGLTSSITTTETTSHSTPG-FTSSITTT 596 Query: 389 RTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTV 448 T S T P + + + + S TA T T + + +S++ + T Sbjct: 597 ETTSEST------PSLSSSTIYSTVSTSTTAITSHFTTSETAVTPTPVTPSSLSTDIPTT 650 Query: 449 SLQPEKPVVSGTAVTLS----LPAV-----TFGETSGAAICLPSVKPVVSSAGTTSDKPV 499 SL+ P GT+ +L+ P++ T + PS++ +S+ + P Sbjct: 651 SLRTLTPSSVGTSTSLTTTTDFPSIPTDISTLPTRTHIISSSPSIQSTETSSLVGTTSPT 710 Query: 500 IGT-PVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNEKQVTTISHS-STLTIQKC 557 + T + +++ + P+ S I V + + Q P T S + +T+T Sbjct: 711 MSTVRMTLRITENTPISSFSTSI---VVIPETPTQTPPVLTSATGTQTSPAPTTVTFGST 767 Query: 558 GQKTMPVNTIIPTSQFPPASILKQITLPGNKILSLQASP------TQKNRIKENVTSCF- 610 T ++T+ P++ Q+ +P +LQ +P T E T F Sbjct: 768 DSSTSTLHTLTPSTALSTIVSTSQVPIPSTHSSTLQTTPSTPSLQTSLTSTSEFTTESFT 827 Query: 611 RDEDDINDV-TSMAGVNLNEENACILATN------SELVGTLIQSCKDEPFLF 656 R N + TS + + + I++++ + + T I S P++F Sbjct: 828 RGSTSTNAILTSFSTIIWSSTPTIIMSSSPSSASITPVFSTTIHSVPSSPYIF 880 Score = 40.8 bits (94), Expect = 0.005 Identities = 60/250 (24%), Positives = 90/250 (36%), Gaps = 39/250 (15%) Query: 344 CVQQTSSDMVIATCTTTVTTSPV--VTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAG 401 CV T + +T VT PV VT+T S + +EK ++ T + +T Sbjct: 145 CVTTTQVAFTSSYTSTPVTQKPVTTVTSTYSMTTTEKGTSAMTSSPSTTTARETPIVTVT 204 Query: 402 PVGAKAGVVTLHSV--GPTAATGGTTAGTGLLQTS---KPLVTSVANTVTTVSLQPEKPV 456 P A T H+ T T T TG + T+ P+ T++ VT+ S P+ Sbjct: 205 PSSVSATDTTFHTTISSTTRTTERTPLPTGSIHTTTSPTPVFTTLKTAVTSTS-----PI 259 Query: 457 VSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGTT--SDKPVIGTPVQIKLAQPGPV 514 S T ++ ++T P+ +SS T S PV+ T Sbjct: 260 TSSITSTNTVTSMT------TTASQPTATNTLSSPTRTILSSTPVLSTE----------- 302 Query: 515 LSQPAGIPQAVQVKQLVVQQP---SGGNEKQVTTISHSSTLTI----QKCGQKTMPVNTI 567 + +GI + LV P S TT S T T+ K T T+ Sbjct: 303 -TITSGITNTTPLSTLVTTLPTTISRSTPTSETTYPTSPTSTVTDSTTKIAYSTSMTGTL 361 Query: 568 IPTSQFPPAS 577 + PP S Sbjct: 362 STETSLPPTS 371 Score = 38.5 bits (88), Expect = 0.027 Identities = 60/286 (20%), Positives = 108/286 (37%), Gaps = 57/286 (19%) Query: 337 SQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTL 396 + ++ ++ +S M + TTT +P+VT T S S+ + T T+S T Sbjct: 171 TSTYSMTTTEKGTSAMTSSPSTTTARETPIVTVTPS------SVSATDTTFHTTISSTTR 224 Query: 397 NPLAGPVGAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVA---------NTVTT 447 P+ PT + TT+ T + T K VTS + NTVT+ Sbjct: 225 TTERTPL-------------PTGSIHTTTSPTPVFTTLKTAVTSTSPITSSITSTNTVTS 271 Query: 448 VSLQPEKPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKP----VIGTP 503 ++ +P + TLS P T ++ P + ++G T+ P V P Sbjct: 272 MTTTASQPTATN---TLSSPTRTILSST------PVLSTETITSGITNTTPLSTLVTTLP 322 Query: 504 VQIKLAQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKTM- 562 I + P + P P+ T I++S+++T + ++ Sbjct: 323 TTISRSTPTSETTYPT--------------SPTSTVTDSTTKIAYSTSMTGTLSTETSLP 368 Query: 563 PVNTIIPTSQFPPASILKQITLPGNKILSLQASPTQKNRIKENVTS 608 P ++ +PT++ + +T +I S + I VTS Sbjct: 369 PTSSSLPTTETATTPMTNLVTTT-TEISSHSTPSFSSSTIYSTVTS 413 Score = 36.2 bits (82), Expect = 0.13 Identities = 77/396 (19%), Positives = 137/396 (34%), Gaps = 39/396 (9%) Query: 94 VAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLM-----LVSPQQTVTRAETTSNITSRP 148 V+ T T +F ++ P TVL+ S + + +++ + TT+ + Sbjct: 96 VSSNTSTTPTSKFAFKVETTPPTVLVYSATTECVYPTSFIITISHPTSICVTTTQVAFTS 155 Query: 149 AVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVV 208 + + P T K T S+ ++T +K GT+ +T+ P ++ + T +V Sbjct: 156 SYTSTPVTQKPVTTVTST------YSMTTTEK----GTSAMTSSPSTTTARE----TPIV 201 Query: 209 TVTPGKPLNTVTTLKPSSLGASSTPSNEP-------NLKAENSAAVQINLSPTMLENVKK 261 TVTP T TT + + T P + + + T + Sbjct: 202 TVTPSSVSATDTTFHTTISSTTRTTERTPLPTGSIHTTTSPTPVFTTLKTAVTSTSPITS 261 Query: 262 CKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAK--IEAEEFTRKLYVELKSSPQPHL 319 + + + SQ P + +L + + E T + ++P L Sbjct: 262 SITSTNTVTSMTTTASQ-PTATNTLSSPTRTILSSTPVLSTETITSGI---TNTTPLSTL 317 Query: 320 VPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKS 379 V L ++ + P S++ T +D +T T + T T S Sbjct: 318 VTTLPTTI---SRSTPTSETTYPTSPTSTVTDSTTKIAYSTSMTGTLSTETSLPPTSSSL 374 Query: 380 IIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAATGGTTAGTGLLQT---SKP 436 AT P T V T ++ T++S + +T T+ +T S P Sbjct: 375 PTTETATTPMTNLVTTTTEISSHSTPSFSSSTIYSTVTSHSTPRFTSSITTTETPSHSTP 434 Query: 437 LVT-SVANTVTTVSLQPEKPVVSGTAVTLSLPAVTF 471 T S NT TT P + T T S +F Sbjct: 435 RFTSSFTNTKTTSHRSPSFTSLITTTETTSHSTPSF 470 >gi|98986457 host cell factor 1 [Homo sapiens] Length = 2035 Score = 62.0 bits (149), Expect = 2e-09 Identities = 137/616 (22%), Positives = 227/616 (36%), Gaps = 104/616 (16%) Query: 14 PAAVSASGTVTMAPA---GALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTLV 70 P A + + VTM PA G PV V S P + V S S P S + L Sbjct: 492 PQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQ-SAQGTVIGSSPQMSGMAALA 550 Query: 71 T------KVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSG 124 K+ P SAP +S + +AV P TTT+ PA +++ V++ + + Sbjct: 551 AAAAATQKIPPSSAPTVLSVPAGTTIVKTMAV-TPGTTTL--PATVKVASSPVMVSNPAT 607 Query: 125 PLMLVSPQQTVTRAETTSNITSRPAVPANPQ-TVKIC----------------------- 160 ++ + Q T + +N ++RP + + TV + Sbjct: 608 RMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSP 667 Query: 161 -TVPNSSS------QLIKKVAVTPVKKLA---QIGTTVVTTVPKPSSVQSVAVPTSVVTV 210 +VP S+ +++ V PV+ A Q T VT + + +VT Sbjct: 668 ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTS 727 Query: 211 TPGKPLNTVTT-------LKPSSLGASST------PSNEPNLKAENSAAVQINLSPTMLE 257 GKP +TT KP+ LG SS P +K +A+ T + Sbjct: 728 ADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVT 787 Query: 258 NVKKCKNFLAML-IKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRKL-YVELKSSP 315 + K+ + ++ K+ SG+ +P K++ + KI + + V LK +P Sbjct: 788 SSPGIKSPITIITTKVMTSGTGAP------AKIITAV--PKIATGHGQQGVTQVVLKGAP 839 Query: 316 QPHLVPFLKKSVVALRQLLPNSQSFIQQC-----VQQTSSDMVIATCTTTVTTSPVVTTT 370 + +R + P + S ++ V+ T+ + T T TV+TS Sbjct: 840 GQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGG 899 Query: 371 VSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAATGGTTAGTGL 430 S+S S + I + T T+S Q +NP A + A TL TAA G TT + Sbjct: 900 HSTSASLATPITTLGTI-ATLSSQVINPTA--ITVSAAQTTL-----TAAGGLTTPTITM 951 Query: 431 LQTSKPLVTSVANTVTTVSLQP--EKPVVSGTAVTLSLPAVTF-------GETSGAAICL 481 S+P ++ + V QP + PV + T P T G+ + L Sbjct: 952 QPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTL 1011 Query: 482 PSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNEK 541 P + T + T V++ G PQ QV Q V + Sbjct: 1012 VCSNPPCETHETGTTNTATTT-----------VVANLGGHPQPTQV-QFVCDRQEAAASL 1059 Query: 542 QVTTISHSSTLTIQKC 557 +T+ + ++ C Sbjct: 1060 VTSTVGQQNGSVVRVC 1075 Score = 52.0 bits (123), Expect = 2e-06 Identities = 119/547 (21%), Positives = 200/547 (36%), Gaps = 67/547 (12%) Query: 89 PAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRP 148 P P V + NT +++ + L++ + P T T N P Sbjct: 365 PPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDI----PATAATATSPTPNPV--P 418 Query: 149 AVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKPS-SVQSVAVPTSV 207 +VPANP + Q + +V +T + + A T T P+ S++VPT+ Sbjct: 419 SVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAA 478 Query: 208 VT-------------VTPGKPLNTVTTLKPSSLGASSTPSNEPNLKAENSAAVQI-NLSP 253 T T G PL T++P+S A P +L A V + Sbjct: 479 RTQGVPAVLKVTGPQATTGTPL---VTMRPAS-QAGKAPVTVTSLPAGVRMVVPTQSAQG 534 Query: 254 TMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEA-EEFTRKLYVELK 312 T++ + + A+ A + P V + K A T L +K Sbjct: 535 TVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVK 594 Query: 313 SSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTT---VTTSPVVTT 369 + P +V S A R L + Q + + AT T+T +T T Sbjct: 595 VASSPVMV-----SNPATRML--------KTAAAQVGTSVSSATNTSTRPIITVHKSGTV 641 Query: 370 TVSSSQSEKSIIVSGATAPRT-----VSVQTLNPLAGPVGAKAGVVTLHSVGPTAATGGT 424 TV+ + +V G T T +SV + L +G VV V +A TG Sbjct: 642 TVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQA 701 Query: 425 TAG--TGLLQTSKPL-VTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAICL 481 + G T ++QT PL ++ VT+ +P T + + A G T + + Sbjct: 702 STGPVTQIIQTKGPLPAGTILKLVTSADGKP-------TTIITTTQASGAG-TKPTILGI 753 Query: 482 PSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNEK 541 SV P + GTT+ I I A V S P + V+ +G K Sbjct: 754 SSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAK 813 Query: 542 QVTTISHSSTLTIQKCGQKTMPVNTIIPTSQFPPASILKQITLPGNKILSLQASPTQKNR 601 +T + +T GQ+ + ++ + P +IL+ + + G +++ +P + Sbjct: 814 IITAVPKIAT----GHGQQGV-TQVVLKGAPGQPGTILRTVPMGGVRLV----TPVTVSA 864 Query: 602 IKENVTS 608 +K VT+ Sbjct: 865 VKPAVTT 871 Score = 44.7 bits (104), Expect = 4e-04 Identities = 112/506 (22%), Positives = 169/506 (33%), Gaps = 70/506 (13%) Query: 13 PPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTL--V 70 P V SGTVT+A + V + K+P+SV L S +G + V Sbjct: 631 PIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISV----PGGSALISNLGKVMSV 686 Query: 71 TKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLVS 130 + PV P QI+ K P LP GT+L S Sbjct: 687 VQTKPVQTSAVTGQASTGPVTQIIQTKGP------------LPAGTILKLVTSAD----G 730 Query: 131 PQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVT 190 T+ S ++P + +V T ++ +IK + ++ + + Q G T VT Sbjct: 731 KPTTIITTTQASGAGTKPTI-LGISSVSPSTTKPGTTTIIKTIPMSAI--ITQAGATGVT 787 Query: 191 TVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLKAENSAAVQIN 250 + P S ++ + T V+T G P +T + + G + LK I Sbjct: 788 SSPGIKSPITI-ITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTI- 845 Query: 251 LSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRKLYVE 310 L + V+ +K A V LV + T + Sbjct: 846 LRTVPMGGVRLVTPVTVSAVKPA------------VTTLVVKGTTGVTTLGTVTGTVSTS 893 Query: 311 LKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTT 370 L + L + L + S I S+ T +TT P +T Sbjct: 894 LAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTT-PTITMQ 952 Query: 371 VSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAAT-------GG 423 S ++ ++I TAP V Q ++ L PV A T PTA G Sbjct: 953 PVSQPTQVTLI----TAPSGVEAQPVHDL--PVSILASPTTEQ---PTATVTIADSGQGD 1003 Query: 424 TTAGTGLLQTSKPLV----TSVANTVTTVSL-------QPEKP--VVSGTAVTLSLPAVT 470 GT L S P T NT TT + QP + V SL T Sbjct: 1004 VQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063 Query: 471 FGETSGAAICLPSVKPV-VSSAGTTS 495 G+ +G+ + + S P GTT+ Sbjct: 1064 VGQQNGSVVRVCSNPPCETHETGTTN 1089 Score = 40.0 bits (92), Expect = 0.009 Identities = 75/330 (22%), Positives = 116/330 (35%), Gaps = 58/330 (17%) Query: 308 YVELKSSPQPHLVPFLKKSVVALRQ---LLPNSQSFIQQCVQQTSSDMVIATCTTTVTTS 364 Y+E + P P V ++ + +L + + S++ Q Q A T+ T + Sbjct: 358 YLETEKPPPPARVQLVRANTNSLEVSWGAVATADSYLLQL--QKYDIPATAATATSPTPN 415 Query: 365 PVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPV--------------GAKAGVV 410 PV + + +S + A P T TL P A P G+ V Sbjct: 416 PVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVP 475 Query: 411 T----------LHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSL---------- 450 T L GP A TG L T +P + VT SL Sbjct: 476 TAARTQGVPAVLKVTGPQATTGTP------LVTMRPASQAGKAPVTVTSLPAGVRMVVPT 529 Query: 451 QPEKPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSS--AGTTSDKPVIGT------ 502 Q + V G++ +S A + PS P V S AGTT K + T Sbjct: 530 QSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTL 589 Query: 503 PVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQQPSGGN--EKQVTTISHSSTLTIQKCGQK 560 P +K+A ++S PA Q+ S N + + T+ S T+T+ Q+ Sbjct: 590 PATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTV---AQQ 646 Query: 561 TMPVNTIIPTSQFPPASILKQITLPGNKIL 590 V T++ + I++PG L Sbjct: 647 AQVVTTVVGGVTKTITLVKSPISVPGGSAL 676 Score = 37.7 bits (86), Expect = 0.046 Identities = 112/550 (20%), Positives = 189/550 (34%), Gaps = 63/550 (11%) Query: 40 VALGAVTKAPVSVCVEPTASQPLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAP 99 VA GA+ A S T S T++ AP SA P + GP + + P Sbjct: 1151 VATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLL--GPSM-------AREP 1201 Query: 100 NTTTIQFPANLQLPPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKI 159 + PA +QL P + ++ +S P + P + A +T+ +T P+ + Sbjct: 1202 GGRS---PAFVQLAPLSSKVRLSS-PSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV 1257 Query: 160 CTV-----PNSS------------SQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVA 202 C P+++ S + +V P + + GTT T S Q V Sbjct: 1258 CESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVC 1317 Query: 203 VPTSVVTVTPGKPLNTVTTLKPSSLG----ASSTPSNEP-NLKAENSAAVQINLSP-TML 256 T G T G P+ P S +++S +L Sbjct: 1318 SNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALL 1377 Query: 257 ENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQ 316 + + +++A + S +P+ G L A + E + Sbjct: 1378 PDATSSHRTVESGLEVAAAPSVTPQAGT--------ALLAPFPTQRVCSNPPCETHETGT 1429 Query: 317 PHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQS 376 H + ++ + + P + Q V+ T D V +T+S +TTTVSS+ + Sbjct: 1430 THTATTVTSNMSSNQDPPPAASD--QGEVESTQGDSV------NITSSSAITTTVSSTLT 1481 Query: 377 EKSIIVSGAT---APRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAATGGTTAGTGLLQT 433 V+ +T P + L GP L S TA G + QT Sbjct: 1482 RAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSAS-TALMGESAEVLSASQT 1540 Query: 434 SK-PLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAG 492 + P +++T S Q V + P T E + LP + AG Sbjct: 1541 PELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVD--QLSLPQELMAEAQAG 1598 Query: 493 TTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQ----AVQVKQLVVQQPSGGNEKQVTTISH 548 TT+ TP ++ + +Q A + A+Q QQ G + + T Sbjct: 1599 TTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEA 1658 Query: 549 SSTLTIQKCG 558 ++T+T + G Sbjct: 1659 AATVTQAELG 1668 Score = 33.5 bits (75), Expect = 0.87 Identities = 56/261 (21%), Positives = 85/261 (32%), Gaps = 39/261 (14%) Query: 4 GLTEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLR 63 GLT P P + T+ AP+G VE+ P V PVS+ PT QP Sbjct: 943 GLTTPTITMQPVSQPTQVTLITAPSG-----VEAQP-----VHDLPVSILASPTTEQP-- 990 Query: 64 SPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNS 123 + T+ P V+ P + NT T ANL P + Sbjct: 991 TATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQV---- 1046 Query: 124 GPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQ 183 Q R E +++ + N V++C+ P + + Sbjct: 1047 --------QFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETH--------------E 1084 Query: 184 IGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLKAEN 243 GTT T + NT TT SS+GA+ A Sbjct: 1085 TGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAM-SSVGANHQRDARRACAAGT 1143 Query: 244 SAAVQINLSPTMLENVKKCKN 264 A ++I+++ LE + K+ Sbjct: 1144 PAVIRISVATGALEAAQGSKS 1164 >gi|38261962 activating transcription factor 7 interacting protein [Homo sapiens] Length = 1270 Score = 61.6 bits (148), Expect = 3e-09 Identities = 107/445 (24%), Positives = 166/445 (37%), Gaps = 72/445 (16%) Query: 11 AAPPAAVSASGTVTMAPAGALPVRVES-----TPVALGAVTK-----APVSVCVEPTASQ 60 +APP+ + TV+ P V S TPV G++T AP + V T Sbjct: 708 SAPPSFQTPVNTVSSTNLVTPPAVVSSQPKLQTPVTSGSLTATSVLPAPNTATVVATTQV 767 Query: 61 PLRSPVGTLVTKVAPV--SAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVL 118 P +P T+ + PV P VSS P+L LQ PGT++ Sbjct: 768 PSGNPQPTISLQPLPVILHVPVAVSSQPQL---------------------LQSHPGTLV 806 Query: 119 IKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPV 178 SG + +S Q T + T N S P++P + + +VP+ S Q P Sbjct: 807 TNQPSGNVEFISVQSPPTVSGLTKNPVSLPSLPNPTKPNNVPSVPSPSIQR------NPT 860 Query: 179 KKLAQIGTTV-VTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKP-----------SS 226 A +GTT+ V VP S+ A TS+ TV P + T P +S Sbjct: 861 ASAAPLGTTLAVQAVPTAHSIVQ-ATRTSLPTVGPSGLYSPSTNRGPIQMKIPISAFSTS 919 Query: 227 LGASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAM----LIKLACSGSQSPEM 282 A + P ++ + + + ++S ++ +C +I L +S Sbjct: 920 SAAEQNSNTTPRIENQTNKTIDASVSKKAADSTSQCGKATGSDSSGVIDLTMDDEES-GA 978 Query: 283 GQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSP-QPHLVPFLKKSVVALRQLLPNSQSFI 341 Q+ KKL + ++ +R L + P QP VP S + LLP + + Sbjct: 979 SQDPKKLNHTPVSTMSSSQPVSRPLQPIQPAPPLQPSGVPTSGPSQTTI-HLLPTAPT-- 1035 Query: 342 QQCVQQTSSDMVIATCTTTVTTSP----VVTTTVSSSQSEKSIIVSGATAPRTVSVQTLN 397 V T + T V +P VV TT+ + ++ + + AP V N Sbjct: 1036 --TVNVTHRPVTQVTTRLPVPRAPANHQVVYTTLPAPPAQAPLRGTVMQAPAVRQVNPQN 1093 Query: 398 PLAGPVGAKAGVV-----TLHSVGP 417 + V V TL S GP Sbjct: 1094 SVTVRVPQTTTYVVNNGLTLGSTGP 1118 >gi|19923559 EMSY protein [Homo sapiens] Length = 1322 Score = 60.1 bits (144), Expect = 9e-09 Identities = 145/646 (22%), Positives = 238/646 (36%), Gaps = 117/646 (18%) Query: 22 TVTM-APAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPV--GTLVTKVAPVSA 78 TVT A A A S PV +K V T S P +PV G++ T +P A Sbjct: 113 TVTANAVANAAIQHNASLPVPAETGSKEVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPA 172 Query: 79 PPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLVSPQQTVTRA 138 P S+ LP+ V VK+ + + + + S+S P++L + V Sbjct: 173 SP-ASNVVVLPSGSTVYVKSVSCSDEDEKPRKRRRTNS----SSSSPVVLKEVPKAVVPV 227 Query: 139 ETTSNITSRPAVPANPQTVKIC-TVPNSSSQLIKKVAVTPVKKLAQIGTT------VVTT 191 T + V +P+ I ++ NS + V +T K Q T +VTT Sbjct: 228 SKTITVP----VSGSPKMSNIMQSIANSLPPHMSPVKITFTKPSTQTTNTTTQKVIIVTT 283 Query: 192 VPKPSSVQSVA------------VPTSVVTVTPGKPLNTVTTLK------PSSLGASSTP 233 P + V ++ VPTSV+ T KP +T + SS +SSTP Sbjct: 284 SPSSTFVPNILSKSHNYAAVTKLVPTSVIASTTQKPPVVITASQSSLVSNSSSGSSSSTP 343 Query: 234 SNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEM----------- 282 S PN A + ++ +P+++ + + IK+A + SP+ Sbjct: 344 SPIPNTVAVTAV---VSSTPSVVMST-VAQGVSTSAIKMASTRLPSPKSLVSAPTQILAQ 399 Query: 283 --GQNVKKLVEQLLDAKIEA-EEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQS 339 Q+ + +QL + + ++ + V + PQ +P K + ++Q +S Sbjct: 400 FPKQHQQSPKQQLYQVQQQTQQQVAQPSPVSHQQQPQQSPLPPGIKPTIQIKQ-----ES 454 Query: 340 FIQQCVQQTSSDMVIATCTT----TVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQT 395 ++ QQ ++ T T + SP++ + + + ++ + T + T Sbjct: 455 GVKIITQQVQPSKILPKPVTATLPTSSNSPIMVVSSNGAIMTTKLVTTPTGTQATYTRPT 514 Query: 396 LNPLAGPVGAKAGVVTL---------------------HSVGPTAATGGTTAGTGLLQTS 434 ++P G + A G T + +G TT T + TS Sbjct: 515 VSPSIGRMAATPGAATYVKTTSGSIITVVPKSLATLGGKIISSNIVSGTTTKITTIPMTS 574 Query: 435 KPLVTSVANTV---TTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVV--- 488 KP V V T TT+ P K VV+ + T L + +P+ Sbjct: 575 KPNVIVVQKTTGKGTTIQGLPGKNVVTTLLNAGGEKTIQTVPTGAKPAILTATRPITKMI 634 Query: 489 ----SSAGTTSDKPVIGTPVQIKLAQPG--PVLSQPAGIP-QAV----QVKQLV---VQQ 534 G+T P +I Q G VL +P + QA Q +QLV +QQ Sbjct: 635 VTQPKGIGSTVQPAAKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTETLQQ 694 Query: 535 PS------------GGNEKQVTTISHSSTLTIQKCGQKTMPVNTII 568 S G E Q T S SS+ + Q + PV +I Sbjct: 695 ASRVAEAGNSSIQEGKEEPQNYTDSSSSSTESSQSSQDSQPVVHVI 740 >gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] Length = 2639 Score = 59.7 bits (143), Expect = 1e-08 Identities = 103/467 (22%), Positives = 158/467 (33%), Gaps = 49/467 (10%) Query: 8 PAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVG 67 P G P + T T+ P P + TP T V+ PT +Q S Sbjct: 1351 PTGTQTPTTTPITTTTTVTPTPT-PTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTSTPI 1408 Query: 68 TLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLM 127 T T V P P +G + P + T T P Q P T + +++ + Sbjct: 1409 TTTTTVTPTPTP----TGTQTPTTTPITTTTTVTPT-PTPTGTQAPTPTAITTTST---V 1460 Query: 128 LVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTT 187 +P T T+ TT+ IT+ V P T ++ V TP Q T+ Sbjct: 1461 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTS 1520 Query: 188 VVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPS-SLGASSTPSNEPNLKAENSAA 246 T + ++V PT T TP P++T TT+ P+ + + TP+ P + Sbjct: 1521 --TPITTTTTVTPTPTPTGTQTPTP-TPISTTTTVTPTPTPTGTQTPTTTP---ITTTTT 1574 Query: 247 VQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRK 306 V +PT + +LI + + +P V + T Sbjct: 1575 VTPTPTPTGTQTP------TTVLITTTTTMTPTPTPTSTKSTTVTPI----------TTT 1618 Query: 307 LYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVT-TSP 365 V +P P ++P S + V T + +T T T T+P Sbjct: 1619 TTVTATPTPTGTQTP----------TMIPISTT---TTVTPTPTPTTGSTGPPTHTSTAP 1665 Query: 366 VVTTTVSSSQSEKSI--IVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAATGG 423 + T S+ E S ++P T S L+ L + + PT +GG Sbjct: 1666 IAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGG 1725 Query: 424 TTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVT 470 T T+ P T T T S P V T + P T Sbjct: 1726 HTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPT 1772 Score = 52.4 bits (124), Expect = 2e-06 Identities = 54/221 (24%), Positives = 77/221 (34%), Gaps = 11/221 (4%) Query: 356 TCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAG----VVT 411 T T T TT+P+ TTT + + + T P T + T+ P P G + + T Sbjct: 1352 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPTPTGTQTPTSTPITT 1410 Query: 412 LHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTF 471 +V PT GT T T+ VT T + P + T P T Sbjct: 1411 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQ 1470 Query: 472 GETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQ-PAGIPQAVQVKQL 530 T+ +V P + GT + P T P P +Q P P Sbjct: 1471 TPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVT 1530 Query: 531 VVQQPSGGNEKQVTTISHSSTLTIQKCGQKTMPVNTIIPTS 571 P+G T IS ++T+T P T PT+ Sbjct: 1531 PTPTPTGTQTPTPTPISTTTTVT-----PTPTPTGTQTPTT 1566 Score = 51.2 bits (121), Expect = 4e-06 Identities = 59/242 (24%), Positives = 84/242 (34%), Gaps = 13/242 (5%) Query: 336 NSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQT 395 N + +Q C T + T T T +P+ TTT + + S P T + T Sbjct: 1286 NYEINVQCCECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTT-T 1344 Query: 396 LNPLAGPVGAK----AGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQ 451 + P P G + + T +V PT GT T T+ VT T T Sbjct: 1345 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-TPTGTQTP 1403 Query: 452 PEKPVVSGTAVT-LSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQ 510 P+ + T VT P T T+ +V P + GT + P T Sbjct: 1404 TSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPT 1463 Query: 511 PGPVLSQ-PAGIPQAVQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKTMPVNTIIP 569 P P +Q P P P+G T I+ ++T+T P T P Sbjct: 1464 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVT-----PTPTPTGTQTP 1518 Query: 570 TS 571 TS Sbjct: 1519 TS 1520 Score = 50.1 bits (118), Expect = 9e-06 Identities = 100/475 (21%), Positives = 157/475 (33%), Gaps = 47/475 (9%) Query: 132 QQTVTRAETTSNITSRP---AVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTV 188 Q T TT N T P P T + + + VTP T Sbjct: 1299 QPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPT 1358 Query: 189 VTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPS-SLGASSTPSNEPNLKAENSAAV 247 T + ++V PT T T P+ T TT+ P+ + + TP++ P Sbjct: 1359 TTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTSTP-------ITT 1410 Query: 248 QINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRKL 307 ++PT + + + + +P Q T Sbjct: 1411 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPT--- 1467 Query: 308 YVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVT-TSPV 366 + P P + V +Q+ + T++ T T T T TS Sbjct: 1468 -----GTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTP 1522 Query: 367 VTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAK----AGVVTLHSVGPTAATG 422 +TTT + + + T + T+ P P G + + T +V PT Sbjct: 1523 ITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 1582 Query: 423 GTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAICLP 482 GT T +L T+ +T T T+ P+ + T VT + P T +T P Sbjct: 1583 GTQTPTTVLITTTTTMTPTP-TPTSTKSTTVTPITTTTTVT-ATPTPTGTQT-------P 1633 Query: 483 SVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNEKQ 542 ++ P +S+ T + P TP P + P + +L P + Sbjct: 1634 TMIP-ISTTTTVTPTP---TPTTGSTGPPTHTSTAP--------IAELTTSNPPPESSTP 1681 Query: 543 VTTISHSSTLTIQKCGQKTMPVNTIIPTSQFPPASILKQITLPGNKILSLQASPT 597 T+ S SS LT T+P I TS PP++ T G LS S T Sbjct: 1682 QTSRSTSSPLTESTTLLSTLP-PAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTT 1735 >gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] Length = 1711 Score = 59.3 bits (142), Expect = 1e-08 Identities = 64/246 (26%), Positives = 101/246 (41%), Gaps = 39/246 (15%) Query: 2 PAGLTEPAGAAPPAAVSASGTVTMAPAGALPVRVE---STPVALGAVTKAPVSVCVE--- 55 P PA + P +S S ++++ + +PV S PV L A AP+SV V Sbjct: 254 PVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPP 313 Query: 56 ---------PTASQPLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQF 106 P+A + +PV T V P S PP + P +P P P +T Sbjct: 314 LALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLI 373 Query: 107 PANLQLPPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSS 166 PA P P + +P T A T + I + +PA+ ++C P + Sbjct: 374 PAFAPTPVPA------PTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVC-FPAAQ 426 Query: 167 SQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSS 226 + ++KV ++ Q GT + + P V +P + G+PL+ T P++ Sbjct: 427 APAMQKVPLS-----FQPGTVLTPSQP------LVYIPPP----SCGQPLSVATL--PTT 469 Query: 227 LGASST 232 LG SST Sbjct: 470 LGVSST 475 Score = 43.9 bits (102), Expect = 6e-04 Identities = 113/483 (23%), Positives = 166/483 (34%), Gaps = 62/483 (12%) Query: 17 VSASGTVTMAPAGALPVRVEST-PVALGAVTKAPVSVCVEPTASQPLRSPVGTLVTKVAP 75 V T +A G V VE T P+ + P +C P A P P Sbjct: 168 VGEKNTFILATLGT-GVPVEGTLPLVTTNFSPLPAPIC--PPAPGSASVPHSVPDAFQVP 224 Query: 76 VSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLVSPQQTV 135 +S P V +P +V AP+ PA PP + S+S PL S +V Sbjct: 225 LSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPL---SVSASV 281 Query: 136 TRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKP 195 S S P VP + +VP S+ L A P T V+ VP P Sbjct: 282 LVPVPASAPPSGP-VPLSAPAPAPLSVPVSAPPLALIQAPVP----PSAPTLVLAPVPTP 336 Query: 196 SSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLKAENSAAVQINLSPTM 255 +P S P P + T PSS G STP+ P +PT Sbjct: 337 ---VLAPMPASTPPAAPAPPSVPMPTPTPSS-GPPSTPTLIP------------AFAPTP 380 Query: 256 LENVKKCKNFLAMLIKL-ACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRKLYVELKSS 314 + F + A + + P A I A ++ + Sbjct: 381 VPAPTPAPIFTPAPTPMPAATPAAIP-------------TSAPIPASFSLSRVCFPAAQA 427 Query: 315 PQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSS 374 P VP + L P C Q S +AT TT+ S +T V S Sbjct: 428 PAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLS----VATLPTTLGVSSTLTLPVLPS 483 Query: 375 QSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTL--HSVGPTAATGGTTAGTG--- 429 + + +P S +A P+ + + +V+L + + T+ +G TT Sbjct: 484 YLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDG 543 Query: 430 ----LLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAV---TLSLPAVTFGETSGAAICLP 482 L TS LVT+ A + T QP P SG++ +P+ T +T G ++ Sbjct: 544 VPGPLADTS--LVTASAKVLPTP--QPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFS 599 Query: 483 SVK 485 +K Sbjct: 600 PLK 602 >gi|161019170 mucin 5AC [Homo sapiens] Length = 6207 Score = 57.4 bits (137), Expect = 6e-08 Identities = 120/532 (22%), Positives = 179/532 (33%), Gaps = 77/532 (14%) Query: 2 PAGLTEPAGAAPPAAVSASGTVTMAP--AGALPVRVES-TPVALGAVTKAPVSVC-VEPT 57 P LT PA P A S+ T + +P A LPV + T +VT P S T Sbjct: 4752 PKVLTSPA--TTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGT 4809 Query: 58 ASQPLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTV 117 + +PV T+ T + P S P + ++ KA T + PGT Sbjct: 4810 LPEQTTTPVATMST-IHPSSTPETTHTST------VLTTKATTTRATSSTSTPSSTPGTT 4862 Query: 118 LIKSN----------SGPLMLVS--PQQT-----VTRAETTSNITSRPAVPAN------- 153 I + +GP S P T +T TT+ T A P++ Sbjct: 4863 WILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWI 4922 Query: 154 ---PQTVKICTVPNSSSQLIKKV---AVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSV 207 P T TVP S+ A TP TV ++ PSS A Sbjct: 4923 LTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPA 4982 Query: 208 VTVTPGKPLNT-VTTLKPSSLGASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFL 266 + T P T T + SSLG + T ++ + + +P E V Sbjct: 4983 LRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTP---ETVHTSTVLT 5039 Query: 267 AMLIKLACSG-----SQSPEMGQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVP 321 A +G S +P K T SSP L P Sbjct: 5040 ATATTTGATGSVATPSSTPGTAHTTK-----------VPTTTTTGFTATPSSSPGTALTP 5088 Query: 322 FLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSII 381 + + + +S +T+ + T T T+T + T T SS+ I+ Sbjct: 5089 PTTTPMSTMSTIHTSS-------TPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRIL 5141 Query: 382 ----VSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSV-GPTAATGGTTAGTGLLQTSKP 436 + T T S TL+ G T+ +V PT +T ++ G T K Sbjct: 5142 TELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKV 5201 Query: 437 LVTSVANTVTTVSLQPEKPVVSGTAVTLSLPA--VTFGETSGAAICLPSVKP 486 + T T S P V T LP+ TF ++ ++ L +++P Sbjct: 5202 VTTMATMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRP 5253 Score = 55.5 bits (132), Expect = 2e-07 Identities = 117/587 (19%), Positives = 200/587 (34%), Gaps = 68/587 (11%) Query: 10 GAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTL 69 G P ++S + + G + E T A + + + P + + Sbjct: 4699 GHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSP 4758 Query: 70 VTKVAPVSAPPKVSSGPR----LPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGP 125 T S+ SS PR LP A K+ T+ P++ GT+ Sbjct: 4759 ATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTL-------- 4810 Query: 126 LMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIG 185 P+QT T T S I P+ + P+T TV + + + + T Sbjct: 4811 -----PEQTTTPVATMSTI--HPS--STPETTHTSTVLTTKATTTRATSSTSTPSSTPGT 4861 Query: 186 TTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLN----TVTTLKPSSLGASSTPSNEPNL-- 239 T ++T + ++ + PT+ + TPG T T +S G+++TPS+ P Sbjct: 4862 TWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTW 4921 Query: 240 ---KAENSAAVQINLSPTMLENVKKCKNFLAMLIKLAC-----SGSQSPEMGQNVKKLVE 291 + +A V + T + + + A S +P + Sbjct: 4922 ILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALP 4981 Query: 292 QLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSD 351 L + A T + + SS L ++ + + S + V +S Sbjct: 4982 AL---RSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVH--TST 5036 Query: 352 MVIATCTTTVTTSPVVT----------------TTVSSSQSEKSIIVSGATAPRTVSVQT 395 ++ AT TTT T V T TT + + S + T P T + T Sbjct: 5037 VLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPTTTPMST 5096 Query: 396 LNPL---AGPVGAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQP 452 ++ + + P V + T AT T + L T++ ++T + T TT + Sbjct: 5097 MSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTR-ILTELTTTATTTA--- 5152 Query: 453 EKPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTP-VQIKLAQP 511 TA S P T+ T + I V P S+A +S TP V +A Sbjct: 5153 ---ATGSTATLSSTPGTTWILTEPSTIATVMV-PTGSTATASSTLGTAHTPKVVTTMATM 5208 Query: 512 GPVLSQPAGIPQAVQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCG 558 + V + PS V+T+S S T++ G Sbjct: 5209 PTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTG 5255 Score = 52.0 bits (123), Expect = 2e-06 Identities = 114/544 (20%), Positives = 177/544 (32%), Gaps = 73/544 (13%) Query: 10 GAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTL 69 G P ++S + G + E T A T ++ + P + + Sbjct: 3552 GHCPSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTST 3611 Query: 70 VTKVAPVSAPPKVSSGPR----LPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGP 125 T S+ SS PR LP A K+ T+ P+ GT+ Sbjct: 3612 ATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTL-------- 3663 Query: 126 LMLVSPQQTVTRAETTSNI----TSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKL 181 P+QT T T S I T + T K T +SS L Sbjct: 3664 -----PEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWIL 3718 Query: 182 AQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLKA 241 ++ T TT + + P + +T TVT S+ ASST + LK Sbjct: 3719 TELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKV 3778 Query: 242 ENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAE 301 S A +PT++ + + S SP + L + A Sbjct: 3779 LTSTAT----TPTVISS--------------RATPSSSPGTATALPAL-------RSTAT 3813 Query: 302 EFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTV 361 T + SS L + L Q + + T + +T TT Sbjct: 3814 TPTATSVTAIPSSS-------LGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTT 3866 Query: 362 TTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAAT 421 TT+ T +V++ S + T + T P + P G V + T Sbjct: 3867 TTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSP-----GTALTPPVWISTTT 3921 Query: 422 GGTTAGTGLLQTSKPLVTSVANTVTT---------VSLQPEKPVVSGTAVTLSLPAVTFG 472 TT G+ + +S P T A +TT ++ SGT T +P T Sbjct: 3922 TPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTT-A 3980 Query: 473 ETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQ-PAGIPQAVQVKQLV 531 T G ++ PS V +A T++ ++GT + +P V S PA Q Sbjct: 3981 TTHGRSL-PPSSPHTVRTAWTSATSGILGT---THITEPSTVTSHTPAATTSTTQHSTPA 4036 Query: 532 VQQP 535 + P Sbjct: 4037 LSSP 4040 Score = 50.1 bits (118), Expect = 9e-06 Identities = 123/589 (20%), Positives = 188/589 (31%), Gaps = 82/589 (13%) Query: 5 LTEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRS 64 LTE AA A + S + + G P P L + P + + T+S R Sbjct: 3576 LTEQTTAATTTATTGSTAIPSSTPGTAP-----PPKVLTSTATTPTATSSKATSSSSPR- 3629 Query: 65 PVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTV-LIKSNS 123 T T S K ++ P P TT P P T+ I +S Sbjct: 3630 ---TATTLPVLTSTATKSTATSFTPIPSFTL-----GTTGTLPEQTTTPMATMSTIHPSS 3681 Query: 124 GPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQ 183 P + T+A TT +S + P T I T +++ T Sbjct: 3682 TPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTP 3741 Query: 184 IGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLK--------PSSLGASSTPSN 235 GTT + T +PS+ +V VPT T T T TLK P+ + + +TPS+ Sbjct: 3742 -GTTWILT--EPSTTATVTVPTGS-TATASSTRATAGTLKVLTSTATTPTVISSRATPSS 3797 Query: 236 EPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLD 295 P A +PT I + G+ + Q Sbjct: 3798 SPGTATALPALRSTATTPTATS---------VTAIPSSSLGTAWTRLSQTTTPTATM--- 3845 Query: 296 AKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIA 355 S+ P P + L +++ ++ Sbjct: 3846 -----------------STATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHT 3888 Query: 356 TCTTTVTTSPVVTTTVSSSQSEKS--IIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLH 413 T T TT+ T SS + + + +S T P T T+ P + P G L Sbjct: 3889 TKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTP-TTRGSTVTPSSIP-GTTHTATVLT 3946 Query: 414 SVGPTAATGGTTAGTGLLQTSKPLVT-SVANTVTTV---SLQPEKPVVSGTAVTLSLPAV 469 + T ATG + QTS T V NT T SL P P TA T + + Sbjct: 3947 TTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGI 4006 Query: 470 TFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTP---VQIKLAQPGPVLSQPAGIPQAVQ 526 + S P +++ T P + +P + + P P + P Sbjct: 4007 LGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPG------- 4059 Query: 527 VKQLVVQQPSGGNEKQVT-TISHSSTLTIQKCGQKTMPVNTIIPTSQFP 574 G + T T S + T T+ + P+ T++ T P Sbjct: 4060 -------HTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEP 4101 Score = 49.3 bits (116), Expect = 2e-05 Identities = 64/264 (24%), Positives = 96/264 (36%), Gaps = 22/264 (8%) Query: 1 MPAGLTEPAG-----AAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVE 55 +P G T A A P + + T T+ + A P T AL A+ S Sbjct: 4261 VPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALR----STATT 4316 Query: 56 PTASQPLRSP---VGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQL 112 PTA+ P +GT T+++ + P S P A +T + A Sbjct: 4317 PTATSFTAIPSSSLGTTWTRLSQTTTPTATMS---TATPSSTPETAHTSTVLTTTATTTR 4373 Query: 113 PPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQT-VKICTVPNSSSQLIK 171 G+V S++ + T T T +S P P + T P +S + Sbjct: 4374 ATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVT 4433 Query: 172 KVAVTPVKKLAQIGTTVVTTVPKPS-SVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGAS 230 +V + TT TTV S + S + TS T TP P T TT G S Sbjct: 4434 PSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTH-----GRS 4488 Query: 231 STPSNEPNLKAENSAAVQINLSPT 254 +PS+ ++ ++A L T Sbjct: 4489 LSPSSPHTVRTAWTSATSGTLGTT 4512 Score = 48.1 bits (113), Expect = 3e-05 Identities = 57/227 (25%), Positives = 86/227 (37%), Gaps = 14/227 (6%) Query: 11 AAPPAAVSASGTV-TMAPAGALPVRVESTPVALGAVTKA---PVSVCVEPTASQPLRSPV 66 A PP ++ + T T+ + A P T AL A+ P + V P S S + Sbjct: 2626 APPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPS----SSL 2681 Query: 67 GTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPL 126 GT T+++ + P S P A +T + A G+V S++ Sbjct: 2682 GTTWTRLSQTTTPTATMS---TATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGT 2738 Query: 127 MLVSPQQTVTRAETTSNITSRPAVPANPQT-VKICTVPNSSSQLIKKVAVTPVKKLAQIG 185 + T T T+ +S P P + T P + + ++ A + Sbjct: 2739 AHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVL 2798 Query: 186 TTVVTTVPKPS-SVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASS 231 TT TTV S + S + TS T TP P NT+ T SL SS Sbjct: 2799 TTTTTTVATGSMATPSSSTQTSGTTHTPPVP-NTMATTHGRSLPPSS 2844 Score = 45.4 bits (106), Expect = 2e-04 Identities = 64/265 (24%), Positives = 99/265 (37%), Gaps = 24/265 (9%) Query: 1 MPAGLTEPAG-----AAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVE 55 +P G T A A P + + T T+ + A P T AL A+ S Sbjct: 3114 VPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALR----STATT 3169 Query: 56 PTASQPLRSP---VGTLVTKVAPVSAPPK-VSSGPRLPAPQIVAVKAPNTTTIQFPANLQ 111 PTA+ P +GT T+++ + P +S+ P+ V TTT A Sbjct: 3170 PTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTT----ATTT 3225 Query: 112 LPPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPAN-PQTVKICTVPNSSSQLI 170 G+V S++ + T T T+ +S P P + T P + + Sbjct: 3226 GATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTV 3285 Query: 171 KKVAVTPVKKLAQIGTTVVTTVPKPS-SVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGA 229 ++ + TT TTV S + S + TS T TP P T TT G Sbjct: 3286 TPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTH-----GR 3340 Query: 230 SSTPSNEPNLKAENSAAVQINLSPT 254 S +PS+ ++ ++A L T Sbjct: 3341 SLSPSSPHTVRTAWTSATSGTLGTT 3365 Score = 43.1 bits (100), Expect = 0.001 Identities = 54/219 (24%), Positives = 85/219 (38%), Gaps = 19/219 (8%) Query: 27 PAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTLVTKVAPVSAPPKV---- 82 PA + STP +TK P + ++ +P TL T + PPKV Sbjct: 2582 PATSSTATPSSTPGTTWILTK-PTTTATTTASTGSTATPTSTLRT-----APPPKVLTTT 2635 Query: 83 SSGPRLPAPQIVAVKAPNTTT----IQFPANLQLPPGTVLIKSNSGPLMLVSPQQTVTRA 138 ++ P + + + +P T T ++ A I S+S QT T Sbjct: 2636 ATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPT 2695 Query: 139 ETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSV 198 T S T + P T + T +++ VA TP + GT T VP ++ Sbjct: 2696 ATMSTATPS-STPETAHTSTVLTATATTTGATGSVA-TPS---STPGTAHTTKVPTTTTT 2750 Query: 199 QSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEP 237 A P+S P+ TT P++ G++ TPS+ P Sbjct: 2751 GFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIP 2789 Score = 41.6 bits (96), Expect = 0.003 Identities = 58/236 (24%), Positives = 90/236 (38%), Gaps = 26/236 (11%) Query: 3 AGLTEPAGA-APPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQP 61 A TE G+ A P++ + + P+ V V + A + T+A P S Sbjct: 4228 ATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGT---PHVSTT 4284 Query: 62 LRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKS 121 +P T +K P S+P ++ P L + A T F A I S Sbjct: 4285 ATTPTVTS-SKATPFSSPGTATALPALRST------ATTPTATSFTA----------IPS 4327 Query: 122 NSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKL 181 +S QT T T S T + P T + T ++++ VA TP Sbjct: 4328 SSLGTTWTRLSQTTTPTATMSTATPS-STPETAHTSTVLTTTATTTRATGSVA-TPS--- 4382 Query: 182 AQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEP 237 + GT T VP ++ P+S P+ TT P++ G++ TPS+ P Sbjct: 4383 STPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVP 4438 Score = 40.4 bits (93), Expect = 0.007 Identities = 121/541 (22%), Positives = 175/541 (32%), Gaps = 87/541 (16%) Query: 9 AGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGT 68 A PP + T T A + S+P G P S PT S+ L SP T Sbjct: 2300 ATTPPPTTELETATTTTTQALFSTPQPTSSP---GLTRAPPASTTAVPTLSEGLTSPRYT 2356 Query: 69 LVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLML 128 A + GP PA P T P LP +G L Sbjct: 2357 STLGTA-------TTGGPTTPAGS-TEPTVPGVATSTLPTRSALP-------GTTGSLGT 2401 Query: 129 VSPQQTVTRAETT-SNITSRP---AVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQI 184 P Q T A TT + +RP A A+ + + P +S+L A T + Sbjct: 2402 WRPSQPPTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETT 2461 Query: 185 GTTVVTTVPKPSSVQ-----------SVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTP 233 + + T + + V PTS V G + T ++ + G Sbjct: 2462 MSPLTNTTTSQGTTRCQPKCEWTEWFDVDFPTSGVA---GGDMETFENIRAAG-GKMCWA 2517 Query: 234 SNEPNLKAENSAAVQIN----LSPTMLENVKKCKN----------FLAMLIKLAC----- 274 +AEN V I+ + LE CKN F + L C Sbjct: 2518 PKSIECRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSH 2577 Query: 275 -------SGSQSPEMGQNVKKLVEQ--LLDAKIEAEEFTRKLYVELKSSPQPH-LVPFLK 324 S + +P ++ + + T L+++P P L Sbjct: 2578 CPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTAT 2637 Query: 325 KSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSG 384 V + P+S T++ + T T T+ VT SSS +S Sbjct: 2638 TPTVTSSKATPSSS-------PGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQ 2690 Query: 385 ATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAATGGT---TAGTGLLQTSKPLVTSV 441 T P T ++ T P + P A V + T ATG ++ G T+K T+ Sbjct: 2691 TTTP-TATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTT 2749 Query: 442 ANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIG 501 T S P GTA+T P V T+ +V P S GTT V+ Sbjct: 2750 TGFTATPSSSP------GTALT---PPVWISTTTTPTTRGSTVTP-SSIPGTTHTATVLT 2799 Query: 502 T 502 T Sbjct: 2800 T 2800 Score = 40.0 bits (92), Expect = 0.009 Identities = 117/564 (20%), Positives = 175/564 (31%), Gaps = 88/564 (15%) Query: 2 PAGLTEPAGAAPPAAVSASGTVTMAP--AGALPVRVESTPVALGAVTKAPVSVCVEPTAS 59 PAG TEP P A S T + P G+L S P L T A TAS Sbjct: 2370 PAGSTEP--TVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSRARPTGTAS 2427 Query: 60 QPLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAP--NTTTIQFPANLQ------ 111 + P L T +AP +S P+ +P NTTT Q Q Sbjct: 2428 TASKEP---LTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQPKCEWT 2484 Query: 112 -----------LPPGTVLIKSN---SGPLMLVSPQQTVTRAETTSNI------------- 144 + G + N +G M +P+ RAE + Sbjct: 2485 EWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQVLTCSL 2544 Query: 145 -----------TSRPAVPANPQTVKIC--------TVPNSSSQLIKKVAVTPVKKLAQIG 185 T R + N +C + P +SS L + Sbjct: 2545 ETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTTWILTKPT 2604 Query: 186 TTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPN------- 238 TT TT +S S A PTS + P + T T P+ + +TPS+ P Sbjct: 2605 TTATTT----ASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPA 2660 Query: 239 LKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKI 298 L++ + +++P ++ L+ + S + +L A Sbjct: 2661 LRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATA 2720 Query: 299 EAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCT 358 T + + H + +S T + T T Sbjct: 2721 TTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPG-----TALTPPVWISTTTT 2775 Query: 359 TTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPT 418 T S V +++ + +++ + T T S+ T P + T H+ P Sbjct: 2776 PTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMAT------PSSSTQTSGTTHT-PPV 2828 Query: 419 AATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAA 478 T TT G L S P A T T + + + VT A T G T + Sbjct: 2829 PNTMATTHGRS-LPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHST 2887 Query: 479 ICLPSVKPVVSSAGTTSDKPVIGT 502 L S P S+ TT P GT Sbjct: 2888 PALSSPHP---SSRTTESPPSPGT 2908 Score = 37.4 bits (85), Expect = 0.060 Identities = 46/180 (25%), Positives = 79/180 (43%), Gaps = 30/180 (16%) Query: 346 QQTSSDMVIATCTTTVT-----TSPVVTTTVSSSQSEKSIIVSGAT--------APRTVS 392 Q T+ ++T T + T TS V+TTT +++++ S+ +T P T + Sbjct: 4339 QTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTT 4398 Query: 393 VQ-TLNPLAGPVGAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKP-------LVTSVANT 444 T+ P + P A+ V + + T TT+G+ + +S P ++T+ T Sbjct: 4399 TGFTVTPSSSPGTARTPPVWI-----STTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTT 4453 Query: 445 VTTVSL--QPEKPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGT 502 V T S+ SGT T +P T T G ++ PS V +A T++ +GT Sbjct: 4454 VATGSMATPSSSTQTSGTTHTPPVPNTT-ATTHGRSLS-PSSPHTVRTAWTSATSGTLGT 4511 Score = 37.0 bits (84), Expect = 0.079 Identities = 56/236 (23%), Positives = 86/236 (36%), Gaps = 26/236 (11%) Query: 3 AGLTEPAGA-APPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQP 61 A TE G+ A P++ + + P+ V V + A + T+A P S Sbjct: 3081 ATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGT---PHVSTT 3137 Query: 62 LRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKS 121 +P T +K P S+P ++ P L + A T F A I S Sbjct: 3138 ATTPTVTS-SKATPFSSPGTATALPALRST------ATTPTATSFTA----------IPS 3180 Query: 122 NSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKL 181 +S QT T T S T + P+TV TV +++ Sbjct: 3181 SSLGTTWTRLSQTTTPTATMSTATPS----STPETVHTSTVLTTTATTTGATGSVATPSS 3236 Query: 182 AQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEP 237 GT T V ++ A P+S P+ TT P++ G++ TPS+ P Sbjct: 3237 TP-GTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIP 3291 Score = 37.0 bits (84), Expect = 0.079 Identities = 90/401 (22%), Positives = 134/401 (33%), Gaps = 89/401 (22%) Query: 148 PAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVP-------KPSSVQS 200 P+ PA T + P ++ ++ K+ T + T ++ P +PS+ + Sbjct: 4200 PSTPATSSTATPSSTPGTT-WILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTAT 4258 Query: 201 VAVPT------SVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLKAENSAAVQINLSPT 254 V VPT S T G P + T P+ + +TP + P A +PT Sbjct: 4259 VTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPT 4318 Query: 255 MLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRKLYVELKSS 314 +F A+ S +G +L + S+ Sbjct: 4319 -------ATSFTAI---------PSSSLGTTWTRLSQTTTPTAT-------------MST 4349 Query: 315 PQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSS 374 P P + L +++ ++ T T TT+ T SS Sbjct: 4350 ATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSP 4409 Query: 375 QSEKS--IIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTA-ATGGTTAGTGLL 431 + ++ + +S T P T S T+ P + P T H+ PT T TT TG + Sbjct: 4410 GTARTPPVWISTTTTP-TTSGSTVTPSSVPG-------TTHT--PTVLTTTTTTVATGSM 4459 Query: 432 QT-SKPLVTS-------VANTVTTV---SLQPEKP---------VVSGTAVTLSL----- 466 T S TS V NT T SL P P SGT T + Sbjct: 4460 ATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPST 4519 Query: 467 -----PAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGT 502 PA T G T + L S P S+ TT P GT Sbjct: 4520 GTSHTPAATTGTTQHSTPALSSPHP---SSRTTESPPSPGT 4557 Score = 35.8 bits (81), Expect = 0.18 Identities = 41/198 (20%), Positives = 77/198 (38%), Gaps = 12/198 (6%) Query: 43 GAVTKAPVSVCVEPTASQPLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTT 102 G P + +S P + + T +T A + ++ P + P+TT Sbjct: 3050 GHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTT 3109 Query: 103 TIQFPANLQLPPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVP-ANPQTVKICT 161 A + +P G+ S++ + V+ TT +TS A P ++P T Sbjct: 3110 -----ATVTVPTGSTATASST---QATAGTPHVSTTATTPTVTSSKATPFSSPGTATALP 3161 Query: 162 VPNSSSQLIKKVAVTPVKKLAQIGTTV--VTTVPKPSSVQSVAVPTSVVTVTPGKPLNTV 219 S++ + T + + +GTT ++ P++ S A P+S + T Sbjct: 3162 ALRSTATTPTATSFTAIPS-SSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTT 3220 Query: 220 TTLKPSSLGASSTPSNEP 237 T + G+ +TPS+ P Sbjct: 3221 TATTTGATGSVATPSSTP 3238 Score = 35.8 bits (81), Expect = 0.18 Identities = 42/160 (26%), Positives = 59/160 (36%), Gaps = 18/160 (11%) Query: 348 TSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKA 407 T++ + T T T+ T SSS +S T P T ++ T P + P Sbjct: 3156 TATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTP-TATMSTATPSSTPETVHT 3214 Query: 408 GVVTLHSVGPTAATGGTTAGT---GLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTL 464 V + T ATG + G T+K L T+ T S P GTA TL Sbjct: 3215 STVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSP------GTARTL 3268 Query: 465 S--LPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGT 502 + T T G+ + S+ GTT V+ T Sbjct: 3269 PVWISTTTTPTTRGSTVTPSSI------PGTTHTPTVLTT 3302 Score = 34.3 bits (77), Expect = 0.51 Identities = 48/178 (26%), Positives = 61/178 (34%), Gaps = 33/178 (18%) Query: 355 ATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGV----- 409 +T T TT + TTT + + S + T P +S T G + + Sbjct: 3236 STPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTH 3295 Query: 410 --VTLHSVGPTAATGGTTAGTGLLQTSKPLVT-SVANTVTTV---SLQPEKP-------- 455 L + T ATG + QTS T V NT T SL P P Sbjct: 3296 TPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWT 3355 Query: 456 -VVSGTAVTLSL----------PAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGT 502 SGT T + PA T G T + L S P S+ TT P GT Sbjct: 3356 SATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHP---SSRTTESPPSPGT 3410 Score = 33.5 bits (75), Expect = 0.87 Identities = 83/388 (21%), Positives = 126/388 (32%), Gaps = 71/388 (18%) Query: 99 PNTTTIQFPANLQLPPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPAN----- 153 P T++ P++ PGT I L T T E+T + + + P Sbjct: 3056 PATSSTAMPSST---PGTTWI--------LTELTTTATTTESTGSTATPSSTPGTTWILT 3104 Query: 154 -PQTVKICTVPNSSSQLIKKV---AVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVT 209 P T TVP S+ A TP TV ++ P S A + Sbjct: 3105 EPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALR 3164 Query: 210 VTPGKPLNTVTTLKPSS--------LGASSTPSNEPNLKAENSAAVQINLSPTMLENVKK 261 T P T T PSS L ++TP+ + +S ++ S T+L Sbjct: 3165 STATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTS-TVLTTTAT 3223 Query: 262 CKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLD---AKIEAEEFTRKLYVELKSSPQPH 318 + + S +P K L + R L V + ++ P Sbjct: 3224 TTGATGSV----ATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTP- 3278 Query: 319 LVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEK 378 + +P + T + V+ T TTTV T + T + S+ S Sbjct: 3279 ----TTRGSTVTPSSIPGT----------THTPTVLTTTTTTVATGSMATPSSSTQTSGT 3324 Query: 379 SII--VSGATA-----------PRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAATGGTT 425 + V TA P TV + +G +G T H P+ T T Sbjct: 3325 THTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLG------TTHITEPSTGTSHTP 3378 Query: 426 AG-TGLLQTSKPLVTSVANTVTTVSLQP 452 A TG Q S P ++S + T P Sbjct: 3379 AATTGTTQHSTPALSSPHPSSRTTESPP 3406 >gi|239757995 PREDICTED: similar to hCG1747327, partial [Homo sapiens] Length = 1064 Score = 57.4 bits (137), Expect = 6e-08 Identities = 118/577 (20%), Positives = 214/577 (37%), Gaps = 84/577 (14%) Query: 17 VSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTLVTKVAPV 76 V+ + + T P PV + + K ++ P+ + +P+ T VT + V Sbjct: 147 VTFTSSYTPTPVTQKPVTTVTRTYPMTTTEKGTSAMISSPSTTTARETPIVT-VTPSSSV 205 Query: 77 SAPPK-----VSSGPR------LPAPQIVAVKAPNT--TTIQFPANLQLPPGTVLIKSNS 123 SA +SS R LP I +P TT++ P + + +N+ Sbjct: 206 SATDTTFHTTISSTTRTTERTPLPTGSIHTTMSPTPVFTTLKTAVTSTSPITSTITSTNT 265 Query: 124 GPLMLVS---PQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKK 180 M + P T T + SNI S VP+ T T N S L+ + T + Sbjct: 266 VTSMTTTTSRPTATNTLSSLMSNILSSTPVPSTEMTTSHTTDTNPLSTLVTTLPTTITRS 325 Query: 181 LAQIGTTV-----------VTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGA 229 TT T + + + PT+ + T T T + P++ Sbjct: 326 TPTSETTYPASPTSTVTDSTTEITYSTVLTGTLSPTTTLPPTSSSQQTTETPMTPTTKLV 385 Query: 230 SST--PSNEPNLKAENSAAVQ-INLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNV 286 ++T +++ +L +SA ++ S T + ++ + + + PE+ Sbjct: 386 TTTTETTSQSSLNFSSSAIYSTVSTSTTAISSLPPTSGTMVTSTNIVPTADLKPEL---- 441 Query: 287 KKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQ 346 ++ ++ D +I+A+ +P+ PF + + ++ C Sbjct: 442 --ILLEVHDQRIQAK------------NPRYSQTPFTSSTAT-------SPETTTLTCTN 480 Query: 347 QTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAK 406 S++ + T T TT + T ++ + + SG T T+S T + L+ Sbjct: 481 DISTESL--TTAMTSTTPVISAITPKTTVTSMTTTASGPTTTNTLSSLTSSILSSTPAPN 538 Query: 407 AGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVA-NTVTTVSLQPEKPVVSGTAVTLS 465 V+T H+ TT L T+ P T++A +T T+ + P P +GT VT S Sbjct: 539 TEVITSHTT--------TTTPPSTLVTTLP--TAIARSTPTSETTYPISP--TGT-VTDS 585 Query: 466 LPAVTFGE----TSGAAICLPSVK---PVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQP 518 + +T+ T A LP P + +A T + +G + P + Sbjct: 586 MTEITYSTSMTGTWSTATTLPLTSCSLPTIETATTPTTN--LGNTTTETTSHSTPSFTSS 643 Query: 519 AGIPQAVQVKQLVVQQ--PSGGNEKQVTTISHSSTLT 553 A I V + + PS G TT++ SS T Sbjct: 644 A-IYSTVNISTTTISSFPPSSGTMVTFTTMNPSSLST 679 Score = 56.2 bits (134), Expect = 1e-07 Identities = 114/513 (22%), Positives = 200/513 (38%), Gaps = 66/513 (12%) Query: 12 APPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTLVT 71 AP V S T T P L V + P A+ T P S P SP GT+ Sbjct: 536 APNTEVITSHTTTTTPPSTL---VTTLPTAIARST--PTSETTYPI------SPTGTVTD 584 Query: 72 KVAPVSAPPKV----SSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLM 127 + ++ + S+ LP + + P T P L T S+S P Sbjct: 585 SMTEITYSTSMTGTWSTATTLP---LTSCSLPTIETATTPTT-NLGNTTTETTSHSTPSF 640 Query: 128 LVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQ--IG 185 S + TT+ I+S P P++ V T+ SS L ++ T +K + Q +G Sbjct: 641 TSSAIYSTVNISTTT-ISSFP--PSSGTMVTFTTMNPSS--LSTDISTTTLKNITQPSVG 695 Query: 186 TT-VVTTVPKPSSVQSVAVPTSVVT-VTPGKP----------LNTVTTLKPSSLGASSTP 233 +T +T +S +V+ +++ T VTP P ++T TT P+ ++ Sbjct: 696 STGFLTAATDLTSTFTVSSSSAMSTSVTPSAPSIQNKEISTLVSTTTTTSPTERMTLTST 755 Query: 234 SNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQL 293 N P ++ V + SP+M + + ++ S +P + + E Sbjct: 756 ENTPTSYILTTSPVTYSFSPSMSASSDWTTDTESI--------SSAPAITSTLHTTAEST 807 Query: 294 LDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMV 353 L A FT +E S+ + + ++ +F++ ++D+ Sbjct: 808 L-APTTTNSFTTSANMEPPSTA-------VATTGTGQSTFTSSTATFLETTTLTPTTDI- 858 Query: 354 IATCTTTVTTSPVVTTTVSSSQSEKSIIVSGAT-APRTVSVQTLNPLAGPVGAKAGVVTL 412 T + T + TT ++SS + ++ + S T A R + TL+ L + + V + Sbjct: 859 ---STESFMTPMISTTPITSSMTLRNTMTSMTTAASRPTTTNTLSSLTSSILSSTPVPST 915 Query: 413 HSVGPTAATGGTTAGTGLLQT-SKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTF 471 + T+ T TT+ + L+ T + TS + TT S P V T T ++T Sbjct: 916 EVI--TSQTTNTTSPSTLVTTLPTTITTSTPTSETTYSTSPTSTVTDSTTETTYSTSIT- 972 Query: 472 GETSGAAICLPSVKPVVSSAG--TTSDKPVIGT 502 T I LP+ + + G TS + ++ T Sbjct: 973 -GTLSTEISLPATTSSLITKGISMTSTRNLVTT 1004 Score = 50.1 bits (118), Expect = 9e-06 Identities = 65/279 (23%), Positives = 109/279 (39%), Gaps = 45/279 (16%) Query: 20 SGTVTMAPAGALPVR-VESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTLVTKVAPVSA 78 S T T +P + + E+TP + +T +PV+ P+ S T +S+ Sbjct: 739 STTTTTSPTERMTLTSTENTPTSY-ILTTSPVTYSFSPSMSAS-----SDWTTDTESISS 792 Query: 79 PPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLVSPQQTVTRA 138 P ++S A +A N+ T AN++ PP T + + +G S T T Sbjct: 793 APAITSTLHTTAESTLAPTTTNSFTTS--ANME-PPSTAVATTGTGQSTFTS--STATFL 847 Query: 139 ETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAV---------TPVKKLAQIGTTVV 189 ETT+ + + T I T P +SS ++ T L+ + ++++ Sbjct: 848 ETTTLTPTTDISTESFMTPMISTTPITSSMTLRNTMTSMTTAASRPTTTNTLSSLTSSIL 907 Query: 190 TTVPKPS--------------SVQSVAVPTSVVTVTP-------GKPLNTV---TTLKPS 225 ++ P PS S +PT++ T TP P +TV TT Sbjct: 908 SSTPVPSTEVITSQTTNTTSPSTLVTTLPTTITTSTPTSETTYSTSPTSTVTDSTTETTY 967 Query: 226 SLGASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKN 264 S + T S E +L A S+ + +S T N+ N Sbjct: 968 STSITGTLSTEISLPATTSSLITKGISMTSTRNLVTTTN 1006 Score = 46.2 bits (108), Expect = 1e-04 Identities = 69/294 (23%), Positives = 110/294 (37%), Gaps = 65/294 (22%) Query: 321 PFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSI 380 P +K V + + P + + ++ +S M+ + TTT +P+VT T SSS S Sbjct: 157 PVTQKPVTTVTRTYPMTTT------EKGTSAMISSPSTTTARETPIVTVTPSSSVS---- 206 Query: 381 IVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTS 440 + T T+S T P+ PT + T + T + T K VTS Sbjct: 207 -ATDTTFHTTISSTTRTTERTPL-------------PTGSIHTTMSPTPVFTTLKTAVTS 252 Query: 441 VANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKP-- 498 + +T++ V+ T S P T +S + L S PV S+ TTS Sbjct: 253 TSPITSTIT---STNTVTSMTTTTSRPTATNTLSSLMSNILSST-PVPSTEMTTSHTTDT 308 Query: 499 ------VIGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNEKQVTTISHSSTL 552 V P I + P + PA P+ T I++S+ L Sbjct: 309 NPLSTLVTTLPTTITRSTPTSETTYPA--------------SPTSTVTDSTTEITYSTVL 354 Query: 553 TIQKCGQKTMPVNTIIPTSQFPPASILKQIT----LPGNKILSLQASPTQKNRI 602 T T+ PT+ PP S +Q T P K+++ T ++ + Sbjct: 355 T-----------GTLSPTTTLPPTSSSQQTTETPMTPTTKLVTTTTETTSQSSL 397 Score = 45.8 bits (107), Expect = 2e-04 Identities = 99/467 (21%), Positives = 167/467 (35%), Gaps = 66/467 (14%) Query: 46 TKAPVSVCVEPT---ASQPLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTT 102 T P++ C PT A+ P + +G T+ S P SS I + +TT Sbjct: 603 TTLPLTSCSLPTIETATTPTTN-LGNTTTETTSHSTPSFTSSA-------IYSTVNISTT 654 Query: 103 TIQFPANLQLPP--GTVLIKSNSGPLMLVSPQQTVTRAETTS-NITSRPAVPANPQTVKI 159 TI PP GT++ + P L + T T T ++ S + A Sbjct: 655 TIS-----SFPPSSGTMVTFTTMNPSSLSTDISTTTLKNITQPSVGSTGFLTAATDLTST 709 Query: 160 CTVPNSSSQLIKKVAVTPV------KKLAQIGTTVVTTVP--KPSSVQSVAVPTSVVTVT 211 TV +SS+ +VTP K+++ + +T TT P + + + PTS + T Sbjct: 710 FTVSSSSAM---STSVTPSAPSIQNKEISTLVSTTTTTSPTERMTLTSTENTPTSYILTT 766 Query: 212 PGKPLNTVTTLKPSSLGASSTPS--NEPNLKAENSAAVQINLSPTMLENVKKCKNFLAML 269 + ++ SS + T S + P + + + L+PT + N Sbjct: 767 SPVTYSFSPSMSASSDWTTDTESISSAPAITSTLHTTAESTLAPTTTNSFTTSANMEPPS 826 Query: 270 IKLACSGSQSPEMGQNVKKLVEQLL---DAKIEAEEF------------------TRKLY 308 +A +G+ + +E I E F T Sbjct: 827 TAVATTGTGQSTFTSSTATFLETTTLTPTTDISTESFMTPMISTTPITSSMTLRNTMTSM 886 Query: 309 VELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTS-PVV 367 S P S + +P+++ Q TS ++ T TT+TTS P Sbjct: 887 TTAASRPTTTNTLSSLTSSILSSTPVPSTEVITSQTTNTTSPSTLVTTLPTTITTSTPTS 946 Query: 368 TTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAATGGTTAG 427 TT S+S + V+ +T T S L+ + A +L + G + + Sbjct: 947 ETTYSTSPTS---TVTDSTTETTYSTSITGTLSTEISLPATTSSLITKGISMTSTRNLVT 1003 Query: 428 TGLLQTSKPLVT-------SVANTVTTVSLQP--EKPVVSGTAVTLS 465 T TS T +++ + T +S P P+V+ T +T S Sbjct: 1004 TTNENTSHSTPTFTLTIHSTISTSTTAISSVPTTSGPIVTSTTMTPS 1050 Score = 41.6 bits (96), Expect = 0.003 Identities = 103/556 (18%), Positives = 191/556 (34%), Gaps = 73/556 (13%) Query: 93 IVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPA 152 +V+ T T +F ++ P TVL+ TT + + Sbjct: 91 LVSSNTSTTPTSKFAFKVETTPPTVLVY-----------------LATTECVYPTSFIIT 133 Query: 153 NPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQ-----------SV 201 IC +++Q+ + TP + TTV T P ++ + + Sbjct: 134 ISHPTSICV---TTTQVTFTSSYTPTPVTQKPVTTVTRTYPMTTTEKGTSAMISSPSTTT 190 Query: 202 AVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLKAENSAAVQINLSPTMLENVKK 261 A T +VTVTP ++ T +++ +++ + L + ++ +SPT + K Sbjct: 191 ARETPIVTVTPSSSVSATDTTFHTTISSTTRTTERTPLP---TGSIHTTMSPTPVFTTLK 247 Query: 262 CKNFLAMLIKLACSGSQS----------PEMGQNVKKLVEQLLDA-KIEAEEFTRKLYVE 310 I + + + P + L+ +L + + + E T + Sbjct: 248 TAVTSTSPITSTITSTNTVTSMTTTTSRPTATNTLSSLMSNILSSTPVPSTEMTTSHTTD 307 Query: 311 LKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTT 370 ++P LV L ++ + P S++ T +D +TV T + TT Sbjct: 308 --TNPLSTLVTTLPTTIT---RSTPTSETTYPASPTSTVTDSTTEITYSTVLTGTLSPTT 362 Query: 371 VSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAATGGTTAGTGL 430 S P T V T ++S T+ TTA + L Sbjct: 363 TLPPTSSSQQTTETPMTPTTKLVTTTTETTSQSSLNFSSSAIYSTVSTS----TTAISSL 418 Query: 431 LQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSS 490 TS +VTS N V T L+PE ++ + + +T P SS Sbjct: 419 PPTSGTMVTS-TNIVPTADLKPELILLEVHDQRIQAKNPRYSQT-----------PFTSS 466 Query: 491 AGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNEKQVT-TISHS 549 T+ + + I ++ + A+ K V + + T T+S Sbjct: 467 TATSPETTTLTCTNDISTESLTTAMTSTTPVISAITPKTTVTSMTTTASGPTTTNTLSSL 526 Query: 550 STLTIQKCGQKTMPVNTIIPTSQFPPASILKQITLPGNKILSLQASPTQKNRIKENVTSC 609 ++ + V T T+ PP++++ TLP +++PT + + T Sbjct: 527 TSSILSSTPAPNTEVITSHTTTTTPPSTLV--TTLP---TAIARSTPTSETTYPISPTGT 581 Query: 610 FRDE-DDINDVTSMAG 624 D +I TSM G Sbjct: 582 VTDSMTEITYSTSMTG 597 Score = 40.8 bits (94), Expect = 0.005 Identities = 49/221 (22%), Positives = 91/221 (41%), Gaps = 28/221 (12%) Query: 22 TVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTLVTKVAPVSAPPK 81 T T+ P + TP+ ++ P+ T+S LR+ + ++ T + + Sbjct: 849 TTTLTPTTDISTESFMTPM----ISTTPI------TSSMTLRNTMTSMTTAASRPTTTNT 898 Query: 82 VSS-------GPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLVSPQQT 134 +SS +P+ +++ + NTT+ P+ L T + S S T Sbjct: 899 LSSLTSSILSSTPVPSTEVITSQTTNTTS---PSTLVTTLPTTITTSTPTSETTYSTSPT 955 Query: 135 VTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIG------TTV 188 T ++T+ T ++ T +I +SS + K +++T + L +T Sbjct: 956 STVTDSTTETTYSTSITGTLST-EISLPATTSSLITKGISMTSTRNLVTTTNENTSHSTP 1014 Query: 189 VTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGA 229 T+ S++ + S V T G P+ T TT+ PSSL A Sbjct: 1015 TFTLTIHSTISTSTTAISSVPTTSG-PIVTSTTMTPSSLTA 1054 Score = 33.9 bits (76), Expect = 0.67 Identities = 37/162 (22%), Positives = 59/162 (36%), Gaps = 8/162 (4%) Query: 35 VESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIV 94 + STPV T+ S T+ L + + T +T P S +S Sbjct: 907 LSSTPVPS---TEVITSQTTNTTSPSTLVTTLPTTITTSTPTSETTYSTSPTSTVTDSTT 963 Query: 95 AVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANP 154 + T + LP T + + G M + T E TS+ T + + Sbjct: 964 ETTYSTSITGTLSTEISLPATTSSLITK-GISMTSTRNLVTTTNENTSHSTPTFTLTIHS 1022 Query: 155 ----QTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTV 192 T I +VP +S ++ +TP A I TT +TT+ Sbjct: 1023 TISTSTTAISSVPTTSGPIVTSTTMTPSSLTADIPTTTLTTI 1064 >gi|239752523 PREDICTED: intestinal mucin-like, partial [Homo sapiens] Length = 514 Score = 57.0 bits (136), Expect = 7e-08 Identities = 94/484 (19%), Positives = 187/484 (38%), Gaps = 68/484 (14%) Query: 15 AAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEP------------TASQPL 62 +A++ + TVT P ++ L ++T + +S + P T S PL Sbjct: 54 SAITPTNTVTSMTTMTSPPTTTNSNSTLSSLTSSILSSTLVPSTDMITSHTTNLTRSSPL 113 Query: 63 RSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSN 122 + + T +T+ P S ++ P P + +TT+I++ ++ GT+ ++++ Sbjct: 114 LATLPTTITRSTPTSE----TTYPTSPTSTVKG----STTSIRYSTSMT---GTLSMETS 162 Query: 123 SGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLA 182 P P TT+ +T+ + + P+ SS I TP Sbjct: 163 LPPTSSSLPTTETATTPTTNLVTTE---------ITSHSTPSFSSSTIHSTVSTP----- 208 Query: 183 QIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLKA- 241 TTV+++ P S ++ + +++ PL T TT+ S+G++ + +L + Sbjct: 209 ---TTVISSGPPTSGTIVTSITVTPSSLSTDIPLTTPTTITHHSVGSTESLLTATDLTST 265 Query: 242 ---ENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKI 298 +S+A+ + P+ +++ + + + A S P L LL Sbjct: 266 FTVSSSSAMSTSDIPSS-PSIQNTETSSLVSMTSATIPSVRPTFTSTHNTLTSSLLTTFP 324 Query: 299 EAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPN------SQSFIQQCVQQTSSDM 352 F+ + + + L S L + + SF ++ S Sbjct: 325 GTYSFSSSMSASSDGTTHTETITSLPASTSTLHTTAESTTAHTTTTSFTTSTTMESPSSS 384 Query: 353 VIATCT-------TTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGA 405 V T T +T T + T T ++ SE+++ + + P S T P Sbjct: 385 VATTSTGQTTFSSSTATFTETTTLTPTTDFSEETLTTAMTSTPPITSSIT------PTNT 438 Query: 406 KAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVS--GTAVT 463 + T+ S PTA ++ T +L +S P+ ++ T T ++ P +V+ T +T Sbjct: 439 VTSMTTMTS-WPTATNTLSSLTTNIL-SSTPVPSTERTTSHTTNINPVSTLVTTLPTTIT 496 Query: 464 LSLP 467 S P Sbjct: 497 RSTP 500 Score = 40.8 bits (94), Expect = 0.005 Identities = 94/478 (19%), Positives = 170/478 (35%), Gaps = 63/478 (13%) Query: 161 TVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVT 220 T +S++ + + +TP +++ +++T + + + S PT+ VT T Sbjct: 17 TFTSSTATFPETITLTPNTNMSR--ESLMTPMTSTTPITSAITPTNTVTSM------TTM 68 Query: 221 TLKPSSLGASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSP 280 T P++ ++ST S+ + ++ ++ + N+ + LA L + + Sbjct: 69 TSPPTTTNSNSTLSSLTSSILSSTLVPSTDMITSHTTNLTRSSPLLATLPTTITRSTPTS 128 Query: 281 EMGQNVK--KLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQ 338 E V+ + + T L +E P +P + + P + Sbjct: 129 ETTYPTSPTSTVKGSTTSIRYSTSMTGTLSMETSLPPTSSSLPTTETATT------PTTN 182 Query: 339 SFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNP 398 + ++ +T +TV+T TT +SS IV+ T + S+ T P Sbjct: 183 LVTTEITSHSTPSFSSSTIHSTVSTP---TTVISSGPPTSGTIVTSITVTPS-SLSTDIP 238 Query: 399 LAGPVGAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQ--PEKPV 456 L P +T HSVG T + T T S S ++ ++ S+Q + Sbjct: 239 LTTPT-----TITHHSVGSTESLLTATDLTSTFTVSSSSAMSTSDIPSSPSIQNTETSSL 293 Query: 457 VSGTAVTLSLPAVTFGE-----TSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQP 511 VS T+ T+ TF TS P SS +SD GT Sbjct: 294 VSMTSATIPSVRPTFTSTHNTLTSSLLTTFPGTYSFSSSMSASSD----GT------THT 343 Query: 512 GPVLSQPAGIPQAVQVKQLVVQQPSGGNEKQVTTI-SHSSTLTIQKCGQKTM-------- 562 + S PA + + + TT+ S SS++ GQ T Sbjct: 344 ETITSLPASTSTLHTTAESTTAHTTTTSFTTSTTMESPSSSVATTSTGQTTFSSSTATFT 403 Query: 563 PVNTIIPTSQFPPASILKQIT---------LPGNKILSLQAS---PTQKNRIKENVTS 608 T+ PT+ F ++ +T P N + S+ PT N + T+ Sbjct: 404 ETTTLTPTTDFSEETLTTAMTSTPPITSSITPTNTVTSMTTMTSWPTATNTLSSLTTN 461 >gi|151301154 mucin 6, gastric [Homo sapiens] Length = 2439 Score = 56.2 bits (134), Expect = 1e-07 Identities = 123/574 (21%), Positives = 191/574 (33%), Gaps = 112/574 (19%) Query: 13 PPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTLVTK 72 PP + A+G+ AP TP G +++P S T++ T + Sbjct: 1879 PPTTIKATGSTHTAPP--------MTPTTSGT-SQSPSSFSTAKTSTSLPYHTSSTHHPE 1929 Query: 73 VAPVSA----PPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLML 128 V P S P S+G R P + + T P PP S++GP+ Sbjct: 1930 VTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPT---PFTTHSPPTGSSPFSSTGPMTA 1986 Query: 129 VSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKK-------VAVTPVKKL 181 S Q T T P++PQT VP S+ L+ T + Sbjct: 1987 TSFQTTTTYP-----------TPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATS 2035 Query: 182 AQIGTTVVTTVPKPSSVQSV-----AVPTSVVTVTPGKPLNTVTTLKPSSL--------- 227 A I +T TVP P+++++ A P +V T + ++ +T SS Sbjct: 2036 ASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLP 2095 Query: 228 -GASSTPSNEP---NLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMG 283 +SS P + P L +SA ++ + + + + + + S SP+ Sbjct: 2096 QNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTS 2155 Query: 284 QNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLV--------------------PFL 323 + A + + + + L + P V P Sbjct: 2156 SPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHT 2215 Query: 324 KKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVS 383 S L LLP S + + IA +T TT+ T SSQS Sbjct: 2216 ISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQS------- 2268 Query: 384 GATAPRTVSVQTLNPLAGPVGAKAGV----------VTLHSVGPT------------AAT 421 T R+ S+ T P +G V +GV +T GPT A Sbjct: 2269 --TTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAH 2326 Query: 422 GGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAICL 481 G T A + P TS V +V Q E+ G + VT GA I Sbjct: 2327 GSTPASAPVSSLGTPTPTSPG--VCSVREQQEEITFKG-----CMANVTVTRCEGACISA 2379 Query: 482 PSVKPVVS--SAGTTSDKPVIGTPVQIKLAQPGP 513 S + A + +P+ Q++L P P Sbjct: 2380 ASFNIITQQVDARCSCCRPLHSYEQQLELPCPDP 2413 Score = 49.3 bits (116), Expect = 2e-05 Identities = 129/647 (19%), Positives = 231/647 (35%), Gaps = 43/647 (6%) Query: 17 VSASGTVTMAP---AGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTLVTKV 73 V+++ T ++ P + V T A + P + PT + P+ S T Sbjct: 1761 VTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSF 1820 Query: 74 APVSAPPKVSSGPRLPAPQIV-----AVKAPNTTTIQFPANLQLPPGTVLIKSNSG---- 124 + P S P P V ++ P+T T+ P + Q+ + +G Sbjct: 1821 QTTTTYP-TPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPP 1879 Query: 125 PLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICT-VP-NSSSQLIKKVAVTPVKKLA 182 P + + T T T + P++ T K T +P ++SS +V T + Sbjct: 1880 PTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNIT 1939 Query: 183 QIGTTVVTTVP--KPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLK 240 T+ T P +S S +PT T +P + ++ P + + T + P Sbjct: 1940 PKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPT-P 1998 Query: 241 AENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEA 300 + + ++ P V + ++I + S + V K Sbjct: 1999 SHPQTTLPTHVPPFSTSLVTPSTH--TVIITTHTQMATSASIHSTPTGTVPPPTTLKATG 2056 Query: 301 EEFTRK-LYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTT 359 T + V + Q H S +S S++ Q +SS + TT Sbjct: 2057 STHTAPPMTVTTSGTSQTHS----SFSTATASSSFISSSSWLPQ---NSSSRPPSSPITT 2109 Query: 360 TVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTA 419 + TT VS++ S +AP TVS + + P + V T S +A Sbjct: 2110 QLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSF-VSA 2168 Query: 420 ATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLP---AVTFGETSG 476 TT +G + T+ +V+ L P P S T + +LP + F ++ Sbjct: 2169 PVHSTTLSSGSHSSLSTHPTTA--SVSASPLFPSSPAAS-TTIRATLPHTISSPFTLSAL 2225 Query: 477 AAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQQPS 536 I +V P SS +S TP P S + ++ L + P+ Sbjct: 2226 LPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRST---SLTTRVPT 2282 Query: 537 GGNEKQVTTISHSSTLTIQKCGQKTMPVNTIIPTSQFPPASILKQITLPGNKILSLQASP 596 G + ++ T + + P T+ PT++F +S+ + P + +S +P Sbjct: 2283 SGFVSLTSGVTGIPTSPVTNLTTR-HPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTP 2341 Query: 597 TQKNRIKENVTSCFRDEDDINDVTSMAGVNLNE-ENACILATNSELV 642 T + V S +++I MA V + E ACI A + ++ Sbjct: 2342 TPTS---PGVCSVREQQEEITFKGCMANVTVTRCEGACISAASFNII 2385 Score = 46.6 bits (109), Expect = 1e-04 Identities = 106/506 (20%), Positives = 171/506 (33%), Gaps = 71/506 (14%) Query: 53 CVEPTASQPLRSP----VGTLVTKVAPVSAPPKV-----SSGPRLPAPQIVAVKAPNTTT 103 C+ PT QP +P G+ T+V P++ S+GP +P A T T Sbjct: 1196 CMPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGP---SPSSNHTPASPTQT 1252 Query: 104 IQFPANLQLPPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVP 163 PA L T P V+PQ T + T+ + S P TV Sbjct: 1253 PLLPATLTSSKPTASSGEPPRPTTAVTPQAT-SGLPPTATLRSTATKP---------TVT 1302 Query: 164 NSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKPS-SVQSVAVPTSVVTVTPGKPLNTVTTL 222 ++++ A AQ T T+P P+ S S +P S PG T Sbjct: 1303 QATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGP 1362 Query: 223 KPSSLGASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEM 282 +P+ + + +P +A T + + +GS P Sbjct: 1363 RPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTH---SPPTAGSPVPST 1419 Query: 283 GQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQ---PHLVPFLKKSVVALRQLLPNSQS 339 G + A F S P+ P VP S+V P++ + Sbjct: 1420 GP-------------VTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVT-----PSTHT 1461 Query: 340 FIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPL 399 I Q ++ + T T P TT ++ + + ++ T+ + + + + Sbjct: 1462 VITPTHAQMATSASNHSAPTG--TIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTN 1519 Query: 400 AGPVGAKAGVVTLH--SVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVV 457 P + + H V PT+ T T TS T VA+T + S +P P Sbjct: 1520 KTPTSLHSHTSSTHHPEVTPTSTTTITPN-----PTSTRTRTPVAHTNSATSSRPPPPFT 1574 Query: 458 SGTAVTLSLP--------------AVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTP 503 + + T S P T+ S LP+ P S++ T + TP Sbjct: 1575 THSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITP 1634 Query: 504 VQIKLAQPGPVLSQPAG-IPQAVQVK 528 ++A + S P G IP +K Sbjct: 1635 THAQMATSASIHSMPTGTIPPPTTLK 1660 Score = 41.6 bits (96), Expect = 0.003 Identities = 117/582 (20%), Positives = 182/582 (31%), Gaps = 93/582 (15%) Query: 4 GLTEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLR 63 GL G +P ++ + T P + + G + +V + T+ P Sbjct: 1231 GLLSSTGPSP-SSNHTPASPTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPT 1289 Query: 64 SPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTT-TIQFPANLQLPPGTVLIKSN 122 + + + TK A + ++ PA A TT T+ PA P L KS Sbjct: 1290 ATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSP--TLPKST 1347 Query: 123 SGPLMLVSPQQTV----TRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPV 178 + L + QT T A TT T +P P P + ++ + T Sbjct: 1348 NQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHT-- 1405 Query: 179 KKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPN 238 T + VP V + + + TP P T+ T P + TPS Sbjct: 1406 ---THSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPS---- 1458 Query: 239 LKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKI 298 ++PT + N A +G+ P Sbjct: 1459 --------THTVITPTHAQMATSASNHSAP------TGTIPPP----------------- 1487 Query: 299 EAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQL-----LPNSQSFIQQCVQQTSSDMV 353 LK++ H P + + Q + + + T V Sbjct: 1488 ----------TTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEV 1537 Query: 354 IATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTL--NPLA--GPVGAKAGV 409 T TTT+T +P T T + S S P T +P + GP+ A + Sbjct: 1538 TPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFK 1597 Query: 410 VTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTV---------TTVSLQ-------PE 453 T + PT + TT T + S LVT +TV T+ S+ P Sbjct: 1598 TT--TTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPP 1655 Query: 454 KPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAG----TTSDKPVIGTPVQIKLA 509 + T T + P +T TSG + L S+ +S T+S T Sbjct: 1656 PTTLKATGSTHTAPTMTL-TTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNI 1714 Query: 510 QPGPVLSQPAGIPQAVQVKQLVVQQPSGGNEKQVTTISHSST 551 P P G P Q S + + +T HS T Sbjct: 1715 TPNPT---STGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHT 1753 Score = 37.7 bits (86), Expect = 0.046 Identities = 121/585 (20%), Positives = 188/585 (32%), Gaps = 93/585 (15%) Query: 15 AAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTLVTKVA 74 A ++ S ++ P G +P +T A G+ AP SQ L S L T Sbjct: 1637 AQMATSASIHSMPTGTIPP--PTTLKATGSTHTAPTMTLTTSGTSQALSS----LNTAKT 1690 Query: 75 PVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLVSPQQT 134 S SS A T P + PP TV S S +T Sbjct: 1691 STSLHSHTSS-----THHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKT 1745 Query: 135 VTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGT-------- 186 T + ++ T P V + T T ++S+ VA T +++ T Sbjct: 1746 STSLHSHTSSTHHPEVTSTSTTS--ITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPP 1803 Query: 187 TVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNL---KAEN 243 T T + V + + T+ TP P T+ T PS + TPS + + Sbjct: 1804 TGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQM 1863 Query: 244 SAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEF 303 + + I+ PT IK S +P M + + + Sbjct: 1864 ATSASIHSMPTGTIPP-------PTTIKATGSTHTAPPMTPTTSGTSQS--PSSFSTAKT 1914 Query: 304 TRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTT 363 + L S+ P + P TS+ + T+T T Sbjct: 1915 STSLPYHTSSTHHPEVTP--------------------------TSTTNITPKHTSTGTR 1948 Query: 364 SPVVTTTVSSSQSEKSIIVS----------GATAPRT-VSVQTLNPLAGPVGAKAGVVTL 412 +PV TT +SS + + +T P T S QT P + TL Sbjct: 1949 TPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQ---TTL 2005 Query: 413 HSVGPTAATGGTTAGTG--LLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVT 470 + P +T T T ++ T + TS + T P + T T + P +T Sbjct: 2006 PTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMT 2065 Query: 471 FGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQVKQL 530 TSG + S +S+ S + P S+P P Q+ L Sbjct: 2066 V-TTSGTSQTHSSFSTATASSSFISSSSWL----------PQNSSSRPPSSPITTQLPHL 2114 Query: 531 VVQQPSGGNEKQVTTISHSSTLTIQKCGQKTMPVNTIIPTSQFPP 575 S TT SS+ + T V++ +P+S P Sbjct: 2115 -----SSATTPVSTTNQLSSSFSPSPSAPST--VSSYVPSSHSSP 2152 >gi|219802034 nuclear factor related to kappaB binding protein isoform 1 [Homo sapiens] Length = 1299 Score = 54.7 bits (130), Expect = 4e-07 Identities = 120/528 (22%), Positives = 196/528 (37%), Gaps = 78/528 (14%) Query: 49 PVSVCVEPTASQPLRSPVGTLVTKVAP--VSAPPKVSSGPRLPAPQIVAVKAPNTTTIQF 106 PV+ + P+ P + V K P VS P K SSG L + + P+ T+ Sbjct: 722 PVTPTTPALPAIPISPPPVSAVNKSGPSTVSEPAKSSSGVLL----VSSPTMPHLGTMLS 777 Query: 107 PANLQLPPGT---VLIKSNSG------------PLMLVSPQQTVTRAETTSNITSRPAVP 151 PA+ Q P + + S+SG P + PQQ+ A+T P +P Sbjct: 778 PASSQTAPSSQAAARVVSHSGSAGLSQVRVVAQPSLPAVPQQSGGPAQTL------PQMP 831 Query: 152 ANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVT 211 A PQ VP +++Q V P TV+ TVP V++ +V Sbjct: 832 AGPQI----RVPATATQ----TKVVP--------QTVMATVP----VKAQTTAATVQRPG 871 Query: 212 PGKPLNTVTTLKPSSLGASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIK 271 PG+ TVT+L ++ S ++ P A +++ + + T +N+ K L Sbjct: 872 PGQTGLTVTSLPATASPVSKPATSSPGTSAPSASTAAVIQNVTG-QNIIKQVAITGQLGV 930 Query: 272 LACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALR 331 +G+ P N + + +L ++ T + P ++ L KS V Sbjct: 931 KPQTGNSIPLTATNFRIQGKDVL--RLPPSSITTDAKGQTVLRITPDMMATLAKSQVTTV 988 Query: 332 QLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTV 391 +L +Q T + + T VT++PV + S ++ S + ++ P Sbjct: 989 KL---TQDLFGTGGNTTGKGI---SATLHVTSNPV---HAADSPAKASSASAPSSTPTGT 1039 Query: 392 SVQTLNPLAGPVGAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQ 451 +V + P P A + L + T +KP T V + + Sbjct: 1040 TVVKVTPDLKPTEASSSAFRLMPALGVSVADQKGKSTVASSEAKPAAT--IRIVQGLGVM 1097 Query: 452 PEKPVVSGTAVTLSLPAVTFGETSG----AAICLPSVKPVVSSAGTTSDKPVIGTPVQIK 507 P K + T T + + SG +A+ LPS+ VS + TP+ I Sbjct: 1098 PPKAGQTITVATHAKQGASVASGSGTVHTSAVSLPSMNAAVSKTVAVA-SGAASTPISIS 1156 Query: 508 LAQPG----PV------LSQPAGIPQAVQVKQLVVQQPSGGNEKQVTT 545 P PV SQ +P + V V+ QP G K V T Sbjct: 1157 TGAPTVRQVPVSTTVVSTSQAGKLPTRITVPLSVISQPMKG--KSVVT 1202 Score = 43.1 bits (100), Expect = 0.001 Identities = 53/205 (25%), Positives = 80/205 (39%), Gaps = 22/205 (10%) Query: 45 VTKAPVSVCVEP----TASQPLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPN 100 VT PV P +AS P +P GT V KV P P + SS P + A Sbjct: 1012 VTSNPVHAADSPAKASSASAPSSTPTGTTVVKVTPDLKPTEASSSAFRLMPALGVSVADQ 1071 Query: 101 TTTIQFPANLQLPPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKIC 160 ++ P T+ I G +M QT+T A S + T + Sbjct: 1072 KGKSTVASSEAKPAATIRIVQGLG-VMPPKAGQTITVATHAKQGASVASGSGTVHTSAV- 1129 Query: 161 TVPNSSSQLIKKVAV--------------TPVKKLAQIGTTVVTTVPKPSSVQSVAVPTS 206 ++P+ ++ + K VAV P + + TTVV+T + VP S Sbjct: 1130 SLPSMNAAVSKTVAVASGAASTPISISTGAPTVRQVPVSTTVVSTSQAGKLPTRITVPLS 1189 Query: 207 VVT-VTPGKPLNTVTTLKPSSLGAS 230 V++ GK + T +K +LGA+ Sbjct: 1190 VISQPMKGKSVVTAPIIK-GNLGAN 1213 Score = 32.0 bits (71), Expect = 2.5 Identities = 34/158 (21%), Positives = 56/158 (35%), Gaps = 18/158 (11%) Query: 449 SLQPEKPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKL 508 S P PV T T +LPA+ I P V V S +T +P Sbjct: 713 SSMPPTPVTPVTPTTPALPAI--------PISPPPVSAVNKSGPSTVSEPA--------K 756 Query: 509 AQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKTMPVNTII 568 + G +L +P + Q + ++ +SHS + + + P + Sbjct: 757 SSSGVLLVSSPTMPHLGTMLSPASSQTAPSSQAAARVVSHSGSAGLSQVRVVAQPSLPAV 816 Query: 569 PTSQFPPASILKQITLPGNKILSLQASPTQKNRIKENV 606 P PA L Q +P + + A+ TQ + + V Sbjct: 817 PQQSGGPAQTLPQ--MPAGPQIRVPATATQTKVVPQTV 852 >gi|23346420 nuclear factor related to kappaB binding protein isoform 2 [Homo sapiens] Length = 1324 Score = 54.7 bits (130), Expect = 4e-07 Identities = 120/528 (22%), Positives = 196/528 (37%), Gaps = 78/528 (14%) Query: 49 PVSVCVEPTASQPLRSPVGTLVTKVAP--VSAPPKVSSGPRLPAPQIVAVKAPNTTTIQF 106 PV+ + P+ P + V K P VS P K SSG L + + P+ T+ Sbjct: 747 PVTPTTPALPAIPISPPPVSAVNKSGPSTVSEPAKSSSGVLL----VSSPTMPHLGTMLS 802 Query: 107 PANLQLPPGT---VLIKSNSG------------PLMLVSPQQTVTRAETTSNITSRPAVP 151 PA+ Q P + + S+SG P + PQQ+ A+T P +P Sbjct: 803 PASSQTAPSSQAAARVVSHSGSAGLSQVRVVAQPSLPAVPQQSGGPAQTL------PQMP 856 Query: 152 ANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVT 211 A PQ VP +++Q V P TV+ TVP V++ +V Sbjct: 857 AGPQI----RVPATATQ----TKVVP--------QTVMATVP----VKAQTTAATVQRPG 896 Query: 212 PGKPLNTVTTLKPSSLGASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIK 271 PG+ TVT+L ++ S ++ P A +++ + + T +N+ K L Sbjct: 897 PGQTGLTVTSLPATASPVSKPATSSPGTSAPSASTAAVIQNVTG-QNIIKQVAITGQLGV 955 Query: 272 LACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALR 331 +G+ P N + + +L ++ T + P ++ L KS V Sbjct: 956 KPQTGNSIPLTATNFRIQGKDVL--RLPPSSITTDAKGQTVLRITPDMMATLAKSQVTTV 1013 Query: 332 QLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTV 391 +L +Q T + + T VT++PV + S ++ S + ++ P Sbjct: 1014 KL---TQDLFGTGGNTTGKGI---SATLHVTSNPV---HAADSPAKASSASAPSSTPTGT 1064 Query: 392 SVQTLNPLAGPVGAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQ 451 +V + P P A + L + T +KP T V + + Sbjct: 1065 TVVKVTPDLKPTEASSSAFRLMPALGVSVADQKGKSTVASSEAKPAAT--IRIVQGLGVM 1122 Query: 452 PEKPVVSGTAVTLSLPAVTFGETSG----AAICLPSVKPVVSSAGTTSDKPVIGTPVQIK 507 P K + T T + + SG +A+ LPS+ VS + TP+ I Sbjct: 1123 PPKAGQTITVATHAKQGASVASGSGTVHTSAVSLPSMNAAVSKTVAVA-SGAASTPISIS 1181 Query: 508 LAQPG----PV------LSQPAGIPQAVQVKQLVVQQPSGGNEKQVTT 545 P PV SQ +P + V V+ QP G K V T Sbjct: 1182 TGAPTVRQVPVSTTVVSTSQAGKLPTRITVPLSVISQPMKG--KSVVT 1227 Score = 43.1 bits (100), Expect = 0.001 Identities = 53/205 (25%), Positives = 80/205 (39%), Gaps = 22/205 (10%) Query: 45 VTKAPVSVCVEP----TASQPLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPN 100 VT PV P +AS P +P GT V KV P P + SS P + A Sbjct: 1037 VTSNPVHAADSPAKASSASAPSSTPTGTTVVKVTPDLKPTEASSSAFRLMPALGVSVADQ 1096 Query: 101 TTTIQFPANLQLPPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKIC 160 ++ P T+ I G +M QT+T A S + T + Sbjct: 1097 KGKSTVASSEAKPAATIRIVQGLG-VMPPKAGQTITVATHAKQGASVASGSGTVHTSAV- 1154 Query: 161 TVPNSSSQLIKKVAV--------------TPVKKLAQIGTTVVTTVPKPSSVQSVAVPTS 206 ++P+ ++ + K VAV P + + TTVV+T + VP S Sbjct: 1155 SLPSMNAAVSKTVAVASGAASTPISISTGAPTVRQVPVSTTVVSTSQAGKLPTRITVPLS 1214 Query: 207 VVT-VTPGKPLNTVTTLKPSSLGAS 230 V++ GK + T +K +LGA+ Sbjct: 1215 VISQPMKGKSVVTAPIIK-GNLGAN 1238 Score = 32.0 bits (71), Expect = 2.5 Identities = 34/158 (21%), Positives = 56/158 (35%), Gaps = 18/158 (11%) Query: 449 SLQPEKPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKL 508 S P PV T T +LPA+ I P V V S +T +P Sbjct: 738 SSMPPTPVTPVTPTTPALPAI--------PISPPPVSAVNKSGPSTVSEPA--------K 781 Query: 509 AQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKTMPVNTII 568 + G +L +P + Q + ++ +SHS + + + P + Sbjct: 782 SSSGVLLVSSPTMPHLGTMLSPASSQTAPSSQAAARVVSHSGSAGLSQVRVVAQPSLPAV 841 Query: 569 PTSQFPPASILKQITLPGNKILSLQASPTQKNRIKENV 606 P PA L Q +P + + A+ TQ + + V Sbjct: 842 PQQSGGPAQTLPQ--MPAGPQIRVPATATQTKVVPQTV 877 >gi|28329416 acute myelogenous leukemia 1 translocation 1 protein isoform MTG8b [Homo sapiens] Length = 604 Score = 54.3 bits (129), Expect = 5e-07 Identities = 58/217 (26%), Positives = 95/217 (43%), Gaps = 25/217 (11%) Query: 155 QTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGK 214 +T K T+P+S + + +TP T+P P + Q +S T Sbjct: 31 RTEKHSTMPDSPVDVKTQSRLTP------------PTMPPPPTTQGAPRTSSFTPTT--- 75 Query: 215 PLNTVTTLKPSSLGASSTP----SNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLI 270 L T+ P++L + +P SN P+ + +S A Q + K K FL L Sbjct: 76 -LTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQ 134 Query: 271 KLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVAL 330 + SPE+G+ V+ LV L+++ + EEF KL +P ++PFLK ++ L Sbjct: 135 QFG--NDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLL 192 Query: 331 -RQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPV 366 R+LL ++ Q Q + + + TTSPV Sbjct: 193 QRELLHCARLAKQNPAQYLAQHEQLLLDAS--TTSPV 227 >gi|4757916 acute myelogenous leukemia 1 translocation 1 protein isoform MTG8a [Homo sapiens] Length = 577 Score = 54.3 bits (129), Expect = 5e-07 Identities = 58/217 (26%), Positives = 95/217 (43%), Gaps = 25/217 (11%) Query: 155 QTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGK 214 +T K T+P+S + + +TP T+P P + Q +S T Sbjct: 4 RTEKHSTMPDSPVDVKTQSRLTP------------PTMPPPPTTQGAPRTSSFTPTT--- 48 Query: 215 PLNTVTTLKPSSLGASSTP----SNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLI 270 L T+ P++L + +P SN P+ + +S A Q + K K FL L Sbjct: 49 -LTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLANQQLPPACGARQLSKLKRFLTTLQ 107 Query: 271 KLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVAL 330 + SPE+G+ V+ LV L+++ + EEF KL +P ++PFLK ++ L Sbjct: 108 QFG--NDISPEIGERVRTLVLGLVNSTLTIEEFHSKLQEATNFPLRPFVIPFLKANLPLL 165 Query: 331 -RQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPV 366 R+LL ++ Q Q + + + TTSPV Sbjct: 166 QRELLHCARLAKQNPAQYLAQHEQLLLDAS--TTSPV 200 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 54.3 bits (129), Expect = 5e-07 Identities = 70/301 (23%), Positives = 107/301 (35%), Gaps = 42/301 (13%) Query: 2 PAGLTEPAGAAPPAAVSASGTV----TMAPAGALPVRVESTPVALGAVTKAPVSVCVEPT 57 P G P A PP+ + GT P P + TP L A T + P+ Sbjct: 1306 PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPT-LPATTPSSKGGPTTPS 1364 Query: 58 ASQPLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTV 117 + + P T K P PP GP +P+P K T+ P + + P T Sbjct: 1365 SKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSP-----KGDPTSPAVIPLSPKKAPATP 1419 Query: 118 LIKSNSGPLM---LVSPQQT---VTRAETTSNITSRPAVPAN--PQTVKICTVPN----- 164 + + + L P T + +A TS PA P++ T+ T P+ Sbjct: 1420 VTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPP 1479 Query: 165 -----SSSQLIKKVAVTPVKKLAQIGTTVVTTVPK-----PSSVQSVAVPTSVV------ 208 ++S KK TP A V+ + PK PSS + PT+ + Sbjct: 1480 APKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTP 1539 Query: 209 -TVTPGKPL--NTVTTLKPSSLGASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNF 265 T+ P + L +T P A TP P + A+ ++P+ + K Sbjct: 1540 ATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKEL 1599 Query: 266 L 266 L Sbjct: 1600 L 1600 Score = 51.2 bits (121), Expect = 4e-06 Identities = 144/614 (23%), Positives = 186/614 (30%), Gaps = 106/614 (17%) Query: 2 PAGLTEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVAL--GAVTKAPVSVCVEPTAS 59 P G A PP+ G T +P GA P +TP + G T +P P A+ Sbjct: 1168 PKGAPTTPAATPPSP--KGGLATPSPKGA-PTTPAATPPSPKGGLATPSPKGAPTTPAAT 1224 Query: 60 QPLRSPVGTLVTK------VAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLP 113 P SP G L T P + PP GP P P+ A P T L P Sbjct: 1225 PP--SPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPK-GAPTPPAATPPSLKGGLATP 1281 Query: 114 PGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKV 173 P K P ++ P + TS P P Sbjct: 1282 PH----KGAPNPAVVTPP--SPKGGPATSPPKGAPTPP---------------------- 1313 Query: 174 AVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVT--TLKPSSLGASS 231 A TP GT P P + VTP P T T PSS G + Sbjct: 1314 AATPPSPKGSPGTPPPKGAPTPPA------------VTPPSPKGTPTLPATTPSSKGGPT 1361 Query: 232 TPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPE-MGQNVKKLV 290 TPS++ PT K AM G P G V Sbjct: 1362 TPSSKE--------------GPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV 1407 Query: 291 EQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSS 350 L K A TR E ++P + + V+L++ S + Sbjct: 1408 IPLSPKKAPATPVTR----EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463 Query: 351 DMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVV 410 D + T P V++S S K P + TL P P K Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATSSSPK----KAPATPAPMGAPTL-PAVIPSSPKEVPA 1518 Query: 411 TLHS----VGPTAA-----TGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTA 461 T S + PTA T T A L V S T + E P + Sbjct: 1519 TPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKT-PAIPTPKEAPATPSSK 1577 Query: 462 VTLSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKP-VIGTPVQIKLAQP--GPVLSQP 518 S PAVT GA PS K ++ TS P TP + P GP P Sbjct: 1578 EASSPPAVTPSTYKGA----PSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAP 1633 Query: 519 AGIPQAVQVKQLVVQ----QPSGGNEKQVTTISHSSTLTIQKCGQKTMPVNTIIPTSQFP 574 G P + V ++ P+ K T+ +S K G + + P + Sbjct: 1634 KGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPEST 1693 Query: 575 PASILKQITLPGNK 588 P IT P K Sbjct: 1694 PI-----ITAPTRK 1702 Score = 49.3 bits (116), Expect = 2e-05 Identities = 64/251 (25%), Positives = 80/251 (31%), Gaps = 22/251 (8%) Query: 2 PAGLTEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTAS-- 59 P G P A PP+ T + A P +P A T P P A+ Sbjct: 982 PKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPP 1041 Query: 60 QPLRSPVGTLVTKVAPVSAP---PKVSSGPRLP----APQIVAVKAPNT---TTIQFPAN 109 P SP T + K AP + P GP P AP A P+ P Sbjct: 1042 SPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG 1101 Query: 110 LQLPPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQL 169 +PP G L +P + S A P T P ++ Sbjct: 1102 APMPPAATPPSPKGG---LATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1158 Query: 170 IKKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVT---VTPGKPLNTVTTLKPSS 226 K TP K A TT T P P + P T TP P + T PS Sbjct: 1159 PKGGLATPPPKGAP--TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT--PSP 1214 Query: 227 LGASSTPSNEP 237 GA +TP+ P Sbjct: 1215 KGAPTTPAATP 1225 Score = 47.8 bits (112), Expect = 4e-05 Identities = 125/588 (21%), Positives = 202/588 (34%), Gaps = 71/588 (12%) Query: 3 AGLTEPAGAAPPAAVSASGTVTMAPAG-ALPVRVESTPVALGAVTKAPVSVCVEPTASQP 61 A L +P PP A ++ A A P ST + P+ V P +S Sbjct: 36 AALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPST------IASTPLEVPF-PQSSSG 88 Query: 62 LRSPVGTLVTKVAPVSAP----PKVSSGPRLPAPQIVAVKAPNTTTIQFP-ANLQLPPGT 116 P+GT AP P P +S A ++A T + P A + L P + Sbjct: 89 TALPLGT--APEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHS 146 Query: 117 VLIKSNSGPLMLVSPQQTVTRAETTSNIT-SRPAVPANPQTVKICTVPNSSSQLIKKVAV 175 V S P +L SP +V AE+ S IT S P P+ P+T + VP+ V Sbjct: 147 VQKSSAFPPNLLTSPP-SVAVAESGSVITLSAPIAPSEPKT-NLNKVPSE---------V 195 Query: 176 TPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKP-------SSLG 228 P K +V+TVP ++ + V ++ P T+ P SS+ Sbjct: 196 VPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVL 255 Query: 229 ASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKK 288 S +LK S ++LS L V + + P+ ++ Sbjct: 256 ISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQK--------TAGPNTPPDFPISLGS 307 Query: 289 LVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQT 348 + L + + + + S P + S A P+ +S I + Sbjct: 308 HLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGA---SYPSQRSVIPPLPSRN 364 Query: 349 SSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQ-TLNPLAGPVGAKA 407 TV PVV +V S S I + V+ +L+P + + Sbjct: 365 E------VVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSS 418 Query: 408 GVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLP 467 T H + T L+ T+ + + T V+ P+ SG P Sbjct: 419 PNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSG-------P 471 Query: 468 AVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQV 527 TS AA+ + V P S + T ++I ++ P P +P +V V Sbjct: 472 ISNIEPTSPAALVMAPVAPKEPST-------QVATTLRIPVSPPLPDPEDLKNLPSSVLV 524 Query: 528 KQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKTMPVNTIIPTSQFPP 575 K P+ + + V + + + G T T++P Q P Sbjct: 525 K-----FPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAP 567 Score = 47.4 bits (111), Expect = 6e-05 Identities = 62/292 (21%), Positives = 96/292 (32%), Gaps = 58/292 (19%) Query: 1 MPAGLTEPAGAAPPAA--VSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTA 58 +PA +T P+ PPA V+ S + APA P+ + P + +P V P++ Sbjct: 1467 LPA-VTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAV---IPSSPKEVPATPSS 1522 Query: 59 SQPLRSPVGTLVTKVAPV---------------------------------------SAP 79 + +P TL++K P S+P Sbjct: 1523 RRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSP 1582 Query: 80 PKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLVSPQQTVTRAE 139 P V+ AP + P T P PP GP + Sbjct: 1583 PAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPV 1642 Query: 140 TTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQ 199 T S++ P PA+ TVP +S L K T +K+ V P P S Sbjct: 1643 TPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKE--------VLVAPAPESTP 1694 Query: 200 SVAVPT-----SVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLKAENSAA 246 + PT + + P+ + K S G ST + P L + ++ Sbjct: 1695 IITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSS 1746 Score = 44.7 bits (104), Expect = 4e-04 Identities = 127/569 (22%), Positives = 188/569 (33%), Gaps = 118/569 (20%) Query: 6 TEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSP 65 T P P ++A+ T T A + + S P++ +P ++ + P A + + Sbjct: 438 TTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPIS-NIEPTSPAALVMAPVAPKEPSTQ 496 Query: 66 VGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQ-FPANLQ---LPPGTVLIKS 121 V T T PVS PP P V VK P +Q PA+L+ P + + Sbjct: 497 VAT--TLRIPVS-PPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTT 553 Query: 122 NSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQT----------------VKICTVP-- 163 P +L Q + + + +S P +P +P+ T P Sbjct: 554 KKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLG 613 Query: 164 -NSSSQLIKKVAVT------PVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPL 216 NSS+ +IK + P+ K + I T V P S A P V T Sbjct: 614 VNSSASVIKTDSYAGPDSAGPLLKSSLI-TPTVAAFPLES-----ADPAGVAPTTAKGTS 667 Query: 217 NTVTTLKPSSLG-ASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACS 275 TT P G S P N P + + L PT EN C Sbjct: 668 TYTTTASPFLEGTVSLAPKNHP---VKEGTLTTLPLVPTASEN---------------CP 709 Query: 276 GSQSPEMGQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVP------FLKKSVVA 329 + SP+ L +L +I KS P P L P K ++ Sbjct: 710 VAPSPQ--NTCAPLATLVLAPEIP------------KSVPSPSLPPAGTPPGTKKVDGIS 755 Query: 330 LRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVT---TSPVVTTTVSSSQSEKSIIVSGAT 386 L S ++C + S A+ T+T SP S Q+++ G+ Sbjct: 756 HTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSA 815 Query: 387 APRTVSVQTLNPLAGPV-------------GAKAGVVTLHSVGPTAATGGTTAGTGLLQT 433 P T + L+ PV G+K T HS P + G T Sbjct: 816 GPDT-PIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSA----- 869 Query: 434 SKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGT 493 VT ++ T+ P K + + V L P G A P P +S + Sbjct: 870 ----VTPLSPKGVTL---PPKETPTPSVVNLPFP------KEGPATPAPKQAPALSMT-S 915 Query: 494 TSDKPVIGTPVQIKLAQPGPVLSQPAGIP 522 +S K TP + P P G P Sbjct: 916 SSPKKARATPAPKGI----PASPSPKGAP 940 Score = 41.6 bits (96), Expect = 0.003 Identities = 64/244 (26%), Positives = 79/244 (32%), Gaps = 54/244 (22%) Query: 2 PAGLTEPAGAAPPAAV-----SASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEP 56 P G+T P P +V G T AP A + + S+ T AP + P Sbjct: 875 PKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASP 934 Query: 57 TASQPLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGT 116 SP G P + PP GP P+P+ AP PP Sbjct: 935 -------SPKGA---PTPPAATPPSPKGGPATPSPK----WAPT------------PPAA 968 Query: 117 VLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVT 176 GP SP+ T T S PA P T P AVT Sbjct: 969 TPPSPKGGP-ATPSPKGAPTPPAATP--PSPKGGPATPSPKGAPTPP----------AVT 1015 Query: 177 PVKKLAQIGTTVVTTVPKPSSVQSVAVPTS------VVTVTPGKPLNTVTTLKPSSLGAS 230 P + G+ T PK +S A P S + G P TL PS G Sbjct: 1016 PP---SPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATL-PSPKGGP 1071 Query: 231 STPS 234 +TPS Sbjct: 1072 ATPS 1075 Score = 35.0 bits (79), Expect = 0.30 Identities = 40/156 (25%), Positives = 62/156 (39%), Gaps = 26/156 (16%) Query: 6 TEPAGAAPPAAVSASG--TVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLR 63 T P P+A + S T+APA LPV+ +S+ A G Sbjct: 1712 TSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKG---------------KDASH 1756 Query: 64 SPVGTLVTKVAPVSAPPKVSSGPR-LPAPQIVAVKAPNTTTIQFPANLQ----LPPGTVL 118 SP G L + S P ++ + LP P+ +V A + + P LPP Sbjct: 1757 SPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQF 1816 Query: 119 IKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANP 154 + S+ G L+L SP + + A+ + P +P P Sbjct: 1817 LPSSPG-LVLESPSKPLAPADEDELL---PLIPPEP 1848 >gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] Length = 3664 Score = 53.1 bits (126), Expect = 1e-06 Identities = 115/530 (21%), Positives = 191/530 (36%), Gaps = 82/530 (15%) Query: 49 PVSVCVEPTASQPLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPA 108 P V EP A + S + + PV+ P S P +P P + +V A A Sbjct: 2437 PAPVDEEPQARFRVHS-----IIESDPVTPP----SDPSIPIPTLPSVTA---------A 2478 Query: 109 NLQLPPGTVLIKSNSGPLMLVS--PQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSS 166 L P + I S P + +Q RA++T + PA P K V SS Sbjct: 2479 KLSPPVASGGIPHQSPPTKVTEWITRQEEPRAQSTPS-------PALPPDTKASDVDTSS 2531 Query: 167 SQLIKKVAVTP--VKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKP 224 S L +K+ + P V + T+V T + +P S V KPL T P Sbjct: 2532 STL-RKILMDPKYVSATSVTSTSVTTAIAEPVSAAPCLHEAPPPPVDSKKPLEEKTA--P 2588 Query: 225 SSLGASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQ 284 S ++E + A+ + ++P + + + M + + SQ + + Sbjct: 2589 PVTNNSEIQASEVLVAADKEKVAPV-IAPKITSVISR------MPVSIDLENSQKITLAK 2641 Query: 285 NVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQC 344 + + L+ A L LVP V AL+ + S + ++ Sbjct: 2642 PAPQTLTGLVSA--------------LTGLVNVSLVP-----VNALKGPVKGSVTTLKSL 2682 Query: 345 VQQTSSDMVIATCTTTVTTSPV--VTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGP 402 V + + + V T PV +TT V+++ + AP TV N A Sbjct: 2683 VSTPAGPVNVLKGPVNVLTGPVNVLTTPVNATVGTVN------AAPGTV-----NAAASA 2731 Query: 403 VGAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAV 462 V A A VT+ + TAA+GG TA TG + + ++ S G+ Sbjct: 2732 VNATASAVTVTAGAVTAASGGVTATTGTVTMAGAVIAPSTKCKQRASANENSRFHPGSMP 2791 Query: 463 TLSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIP 522 + G +G + ++S +G ++ P + K++Q P + Sbjct: 2792 VIDDRPADAGSGAGLRVNTSEGVVLLSYSGQKTEGP---QRISAKISQIPPASAMDIEFQ 2848 Query: 523 QAVQVKQL------VVQQPSGGNEKQV--TTISHSSTLTIQKCGQKTMPV 564 Q+V Q+ Q PS G + ++ STL + PV Sbjct: 2849 QSVSKSQVKPDSVTASQPPSKGPQAPAGYANVATHSTLVLTAQTYNASPV 2898 Score = 30.8 bits (68), Expect = 5.6 Identities = 98/445 (22%), Positives = 164/445 (36%), Gaps = 109/445 (24%) Query: 5 LTEPAGA------APPAAVSASGTVTMAPAGALPVRVESTPVALGAVTK----------- 47 LT P A A P V+A+ + A A A+ V + A G VT Sbjct: 2707 LTTPVNATVGTVNAAPGTVNAAASAVNATASAVTVTAGAVTAASGGVTATTGTVTMAGAV 2766 Query: 48 -APVSVCVE-PTASQPLRSPVGTL-VTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTI 104 AP + C + +A++ R G++ V P A +G R+ + V + + + Sbjct: 2767 IAPSTKCKQRASANENSRFHPGSMPVIDDRPADAGS--GAGLRVNTSEGVVLLSYSGQKT 2824 Query: 105 QFPANL-----QLPPGTVL-IKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQT-- 156 + P + Q+PP + + I+ +VT ++ S PA AN T Sbjct: 2825 EGPQRISAKISQIPPASAMDIEFQQSVSKSQVKPDSVTASQPPSKGPQAPAGYANVATHS 2884 Query: 157 --VKICTVPNSSSQLIKKVAVTP-VKKLAQIGTTVVTTVPKPSSV----QSVAVPTSVV- 208 V N+S + A P ++K I +V T V + +V Q + P +V Sbjct: 2885 TLVLTAQTYNASPVISSVKADRPSLEKPEPIHLSVSTPVTQGGTVKVLTQGINTPPVLVH 2944 Query: 209 --------TVTPGKPLNTVTTLK-------PSSLGASSTPSNEPNLKAENSAAVQINLSP 253 VT K L TLK P++LG++ TP + P L ++ P Sbjct: 2945 NQLVLTPSIVTTNKKLADPVTLKIETKVLQPANLGSTLTPHHPPALPSK---------LP 2995 Query: 254 TMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRKLYVELKS 313 T + +V SG P + V L AK++A Sbjct: 2996 TEVNHVP--------------SGPSIP-----ADRTVSHLAAAKLDAH------------ 3024 Query: 314 SPQPHLVPFLKKSVVALRQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPV-VTTTVS 372 SP+P P SF + +++ ++T T + + + V +S Sbjct: 3025 SPRPS---------------GPGPSSFPRASHPSSTASTALSTNATVMLAAGIPVPQFIS 3069 Query: 373 SSQSEKSIIVSGATAPRTVSVQTLN 397 S E+S+I+ + +TVS+ L+ Sbjct: 3070 SIHPEQSVIMPPHSITQTVSLSHLS 3094 >gi|19111150 angiomotin isoform 2 [Homo sapiens] Length = 675 Score = 53.1 bits (126), Expect = 1e-06 Identities = 46/168 (27%), Positives = 65/168 (38%), Gaps = 17/168 (10%) Query: 1 MPAGLTEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGA---VTKAPVSVCVEPT 57 +PA + A AA A +A+ T TM A + V + P A A T A + V P Sbjct: 474 VPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPA 533 Query: 58 ASQ--PLRSPVGTLVTKVAPVSAPPKVSSGPR----LPAPQIVAVKAPNTTTIQFPANLQ 111 A+ P + V + +A V P +PAP +V V AP PA Q Sbjct: 534 AAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQ 593 Query: 112 LPPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKI 159 P S P + +P T T A + + + PA P + I Sbjct: 594 AP--------TSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSI 633 Score = 30.4 bits (67), Expect = 7.4 Identities = 48/191 (25%), Positives = 64/191 (33%), Gaps = 32/191 (16%) Query: 362 TTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAAT 421 T SPV +T S K T R S QT G K V SV A Sbjct: 431 TPSPVPPSTPLLSAHSK-------TGSRDCSTQTER---GTESNKTAAVAPISVPAPVAA 480 Query: 422 GGTTAGTGLLQTSKPLVTSVANTVTT--VSLQPEKPVVSGTAVTLSLPAVTFGETSGAAI 479 T A +T+ A T+TT V+ P + + P+ + AA+ Sbjct: 481 AATAAA----------ITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAV 530 Query: 480 CLPSVKPV-----VSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQQ 534 + + V+SA + VQ+ A P PV PA P V V Q Sbjct: 531 SPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPV---PA--PALVPVPAPAAAQ 585 Query: 535 PSGGNEKQVTT 545 S + Q T Sbjct: 586 ASAPAQTQAPT 596 >gi|166064029 angiomotin isoform 1 [Homo sapiens] Length = 1084 Score = 53.1 bits (126), Expect = 1e-06 Identities = 46/168 (27%), Positives = 65/168 (38%), Gaps = 17/168 (10%) Query: 1 MPAGLTEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGA---VTKAPVSVCVEPT 57 +PA + A AA A +A+ T TM A + V + P A A T A + V P Sbjct: 883 VPAPVAAAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAVSPA 942 Query: 58 ASQ--PLRSPVGTLVTKVAPVSAPPKVSSGPR----LPAPQIVAVKAPNTTTIQFPANLQ 111 A+ P + V + +A V P +PAP +V V AP PA Q Sbjct: 943 AAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPVPAPALVPVPAPAAAQASAPAQTQ 1002 Query: 112 LPPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKI 159 P S P + +P T T A + + + PA P + I Sbjct: 1003 AP--------TSAPAVAPTPAPTPTPAVAQAEVPASPATGPGPHRLSI 1042 Score = 30.4 bits (67), Expect = 7.4 Identities = 48/191 (25%), Positives = 64/191 (33%), Gaps = 32/191 (16%) Query: 362 TTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAAT 421 T SPV +T S K T R S QT G K V SV A Sbjct: 840 TPSPVPPSTPLLSAHSK-------TGSRDCSTQTER---GTESNKTAAVAPISVPAPVAA 889 Query: 422 GGTTAGTGLLQTSKPLVTSVANTVTT--VSLQPEKPVVSGTAVTLSLPAVTFGETSGAAI 479 T A +T+ A T+TT V+ P + + P+ + AA+ Sbjct: 890 AATAAA----------ITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPATAAATAAAV 939 Query: 480 CLPSVKPV-----VSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQQ 534 + + V+SA + VQ+ A P PV PA P V V Q Sbjct: 940 SPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAPAAPAPV---PA--PALVPVPAPAAAQ 994 Query: 535 PSGGNEKQVTT 545 S + Q T Sbjct: 995 ASAPAQTQAPT 1005 >gi|28329422 acute myelogenous leukemia 1 translocation 1 protein isoform MTG8c [Homo sapiens] Length = 567 Score = 52.8 bits (125), Expect = 1e-06 Identities = 51/181 (28%), Positives = 82/181 (45%), Gaps = 13/181 (7%) Query: 191 TVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTP----SNEPNLKAENSAA 246 T+P P + Q +S T L T+ P++L + +P SN P+ + +S A Sbjct: 18 TMPPPPTTQGAPRTSSFTPTT----LTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLA 73 Query: 247 VQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRK 306 Q + K K FL L + SPE+G+ V+ LV L+++ + EEF K Sbjct: 74 NQQLPPACGARQLSKLKRFLTTLQQFG--NDISPEIGERVRTLVLGLVNSTLTIEEFHSK 131 Query: 307 LYVELKSSPQPHLVPFLKKSVVAL-RQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSP 365 L +P ++PFLK ++ L R+LL ++ Q Q + + + TTSP Sbjct: 132 LQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDAS--TTSP 189 Query: 366 V 366 V Sbjct: 190 V 190 >gi|28329419 acute myelogenous leukemia 1 translocation 1 protein isoform MTG8c [Homo sapiens] Length = 567 Score = 52.8 bits (125), Expect = 1e-06 Identities = 51/181 (28%), Positives = 82/181 (45%), Gaps = 13/181 (7%) Query: 191 TVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTP----SNEPNLKAENSAA 246 T+P P + Q +S T L T+ P++L + +P SN P+ + +S A Sbjct: 18 TMPPPPTTQGAPRTSSFTPTT----LTNGTSHSPTALNGAPSPPNGFSNGPSSSSSSSLA 73 Query: 247 VQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFTRK 306 Q + K K FL L + SPE+G+ V+ LV L+++ + EEF K Sbjct: 74 NQQLPPACGARQLSKLKRFLTTLQQFG--NDISPEIGERVRTLVLGLVNSTLTIEEFHSK 131 Query: 307 LYVELKSSPQPHLVPFLKKSVVAL-RQLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSP 365 L +P ++PFLK ++ L R+LL ++ Q Q + + + TTSP Sbjct: 132 LQEATNFPLRPFVIPFLKANLPLLQRELLHCARLAKQNPAQYLAQHEQLLLDAS--TTSP 189 Query: 366 V 366 V Sbjct: 190 V 190 >gi|112421108 capicua homolog [Homo sapiens] Length = 1608 Score = 52.8 bits (125), Expect = 1e-06 Identities = 64/251 (25%), Positives = 97/251 (38%), Gaps = 27/251 (10%) Query: 14 PAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTL---- 69 PA A GT AP+G P + G T V PT P+ V + Sbjct: 840 PAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPK 899 Query: 70 VTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTT----IQFPANLQLPPGTVLIKSNSGP 125 V+PV APP S LP +V + AP+ + P L PP +V +++ + P Sbjct: 900 AQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQP 959 Query: 126 LMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIG 185 P + + + S P +P T+ P S Q + + T + + G Sbjct: 960 -----PSKIIQLTPVPVSTPSGLVPPLSPATL---PGPTSQPQKVLLPSSTRITYVQSAG 1011 Query: 186 TTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLKAENS- 244 + P+S Q+ TVT P ++V L +SLG S +P L A + Sbjct: 1012 GHALPLGTSPASSQA-------GTVTSYGPTSSV-ALGFTSLGPSGPAFVQPLLSAGQAP 1063 Query: 245 --AAVQINLSP 253 A Q+ +SP Sbjct: 1064 LLAPGQVGVSP 1074 Score = 34.3 bits (77), Expect = 0.51 Identities = 134/614 (21%), Positives = 208/614 (33%), Gaps = 104/614 (16%) Query: 4 GLTEPAG----AAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTAS 59 G EP G AAPP SG + LP E V AP + Sbjct: 607 GGLEPPGPSVIAAPP-----SGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPA 661 Query: 60 QPLRSPVGTLVTKVA-PVSAPPKVSSGPRLPAPQIVAVKAPNTTT---IQFPANLQLPPG 115 PL P T+VT V PVS+ P + P A +PN T + ++P G Sbjct: 662 APLSRPAATMVTNVVRPVSSTPVPIASKPFPTSG-RAEASPNDTAGARTEMGTGSRVPGG 720 Query: 116 TVLIKSNSGPLMLVSPQQTVTRAETTSNITSRP---AVPANPQTVKICTVPNSSSQLIKK 172 + L G ++ S +++ ++ + P V P TV V Sbjct: 721 SPL-----GVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAP 775 Query: 173 VAVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTVTTLK------PSS 226 AV + + A G T + S + VP ++ +T ++ P Sbjct: 776 PAVQFIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQ 835 Query: 227 LGASSTPSNEPNLKA------ENSAAVQINLSPTMLENVKKCKNFLAM--LIKLACSGSQ 278 L + P+ P KA + +++ L P N K + L S Sbjct: 836 LQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSA 895 Query: 279 SPEMGQNVKKL-------VEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALR 331 P Q+V + QLL K+ + V + QP + SV Sbjct: 896 PPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQN 955 Query: 332 QLLPNSQSFIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTV 391 P S + +Q T + ++T + V T +SQ +K ++ S + R Sbjct: 956 GAQPPS-----KIIQLT--PVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPS---STRIT 1005 Query: 392 SVQTLNPLAGPVG-----AKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVT 446 VQ+ A P+G ++AG VT + + A G T+ G +PL++ Sbjct: 1006 YVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLS------- 1058 Query: 447 TVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQI 506 +G A P + G+ + + P + P ++ G PVI Sbjct: 1059 -----------AGQA-----PLLAPGQVGVSPVPSPQLPPACAAPG----GPVI---TAF 1095 Query: 507 KLAQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNEKQVTTISHSST---LTIQKCGQKTMP 563 P P S P + QPS V T++ S+T TI G Sbjct: 1096 YSGSPAPTSSAP-------------LAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPA 1142 Query: 564 VNTIIPTSQFPPAS 577 T PTS FP A+ Sbjct: 1143 TATPAPTSPFPSAT 1156 Score = 31.6 bits (70), Expect = 3.3 Identities = 49/238 (20%), Positives = 80/238 (33%), Gaps = 20/238 (8%) Query: 360 TVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLN--PLAGPVGAKAGVVTLHSVGP 417 T T V+ T + V A P+ SV + P G G V + P Sbjct: 870 TSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAP 929 Query: 418 TAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGA 477 + + G AG L S P V N QP ++ T V +S P+ S A Sbjct: 930 SMSVRGGGAGQPLPLVSPPFSVPVQN-----GAQPPSKIIQLTPVPVSTPSGLVPPLSPA 984 Query: 478 AICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGI-PQAVQVKQLVVQQPS 536 + P+ +P K ++ + +I Q + P G P + Q + P+ Sbjct: 985 TLPGPTSQP---------QKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPT 1035 Query: 537 GGNEKQVTTISHSSTLTIQ---KCGQKTMPVNTIIPTSQFPPASILKQITLPGNKILS 591 T++ S +Q GQ + + S P + PG +++ Sbjct: 1036 SSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVIT 1093 Score = 31.2 bits (69), Expect = 4.3 Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 6/88 (6%) Query: 8 PAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTASQPLRSPVG 67 P+ PPA + G V A P S P+A ++AP S+ T + P Sbjct: 1076 PSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLA--QPSQAPPSLVY--TVATSTTPPAA 1131 Query: 68 TLVTKVAPVSAPPKVSSGPRLPAPQIVA 95 T++ K P AP + P P P A Sbjct: 1132 TILPKGPP--APATATPAPTSPFPSATA 1157 >gi|146219843 Snf2-related CBP activator protein [Homo sapiens] Length = 3230 Score = 52.4 bits (124), Expect = 2e-06 Identities = 95/472 (20%), Positives = 170/472 (36%), Gaps = 51/472 (10%) Query: 2 PAGLTEPAGAAPPAAVSASGTVTMAPAGALPVRVEST-PVALGAVTKAPVSVCVEPTASQ 60 PA P + P A S TV++ + +LP+ V +T P A P+S + +AS Sbjct: 1410 PASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASG 1469 Query: 61 PLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPGTVLIK 120 P L+T V P AP P P P +A + + L P + Sbjct: 1470 P------ALLTSVTPPLAPVV----PAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQ 1519 Query: 121 SNSGPLMLVSPQQTVTRAETTSNITSRPA-VPANPQTVKICTVPN---------SSSQLI 170 + PL+L V +T P VPA+ + PN + + Sbjct: 1520 TPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSA 1579 Query: 171 KKVAVTPVKKLAQIGTTVVTTVPKPS-------SVQSVAVPTSVVTVTPGKPLNTVTTLK 223 + TP+ +A T ++ P P + A P + TP + +T Sbjct: 1580 SQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPG 1639 Query: 224 PSSLGASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMG 283 S AS P+ P L ++ + P+ L + + LA + + +P +G Sbjct: 1640 TSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQT-------LALAPALAPTLG 1692 Query: 284 QNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQQ 343 + L + T+ L + +P LVP +++ L P Q Sbjct: 1693 GSSPSQTLSLGTGNPQGPFPTQTLSL----TPASSLVPTPAQTL----SLAPGPPLGPTQ 1744 Query: 344 CVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPV 403 + + + + V +P T T++ + S S++ AP +V TL+P P Sbjct: 1745 TLSLAPAPPLAP--ASPVGPAPAHTLTLAPASSSASLL-----APASVQTLTLSPAPVPT 1797 Query: 404 GAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKP 455 A TL ++ P + + + L+ ++ V+ + + ++P Sbjct: 1798 LGPAAAQTL-ALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEP 1848 Score = 49.3 bits (116), Expect = 2e-05 Identities = 95/416 (22%), Positives = 152/416 (36%), Gaps = 34/416 (8%) Query: 2 PAGLTEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCV---EPTA 58 PA LT P +A G ++AP+GA P ++ + LG T +S P Sbjct: 1470 PALLTSVTPPLAPVVPAAPGPPSLAPSGASP---SASALTLGLATAPSLSSSQTPGHPLL 1526 Query: 59 SQPLRSPVGTLVTKVAPVSAPPKV---------SSGPRLPAPQIVAVKAPNTTTIQFPAN 109 P S V L + VAP +P V S P PAP ++ AP ++ Q A Sbjct: 1527 LAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPN-PAPAQASLLAPASSASQALAT 1585 Query: 110 LQLP---PGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPA-NPQTVKICTVPNS 165 P P T ++ + P + P + +S+ VP P + ++ ++ Sbjct: 1586 PLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASA 1645 Query: 166 SSQLIKKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAV-PTSVVTVTPGKPLNTVT--TL 222 S + P + V + +P P+S Q++A+ P T+ P T++ T Sbjct: 1646 SPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTG 1705 Query: 223 KPSSLGASSTPSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEM 282 P + T S P + A ++L+P + + LA LA + P Sbjct: 1706 NPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLS-LAPAPPLAPASPVGPAP 1764 Query: 283 GQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQSFIQ 342 + L A A L SP P VP L + L P S Q Sbjct: 1765 AHTL-----TLAPASSSASLLAPASVQTLTLSPAP--VPTLGPAAAQTLALAPAS---TQ 1814 Query: 343 QCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSVQTLNP 398 Q SS +V A+ + + V VS + + + SG +P + + P Sbjct: 1815 SPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGP 1870 Score = 48.9 bits (115), Expect = 2e-05 Identities = 135/600 (22%), Positives = 214/600 (35%), Gaps = 110/600 (18%) Query: 8 PAGAAPPAAVSASGTVTMAPAGALPVRVEST-------PVALGAVTKAPVSVCVEPTASQ 60 P + PA ++ T+T G LP T P + + K S E +AS Sbjct: 1333 PPSSGLPAVLNPRPTLT---PGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASA 1389 Query: 61 PLRSPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANLQLPPG--TVL 118 P +P+ T+ + + S+ P +S P +P P + +P ++T+ P + LP T L Sbjct: 1390 PGAAPL-TISSPLHVPSSLPGPASSP-MPIPNSSPLASPVSSTVSVPLSSSLPISVPTTL 1447 Query: 119 IKSNSGPLMLVSPQQTVTRAETTSNITS-----RPAVPANPQTVKICTVPNSSSQLIKKV 173 S PL + A + +TS P VPA P + S S Sbjct: 1448 PAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPS------ 1501 Query: 174 AVTPVKKLAQIGTTVVTTVPKPSSVQSVAVPTSVVTVTPGKPLNTV-TTLKPSSLGASST 232 A T + T P SS Q TPG PL T+ L ++ Sbjct: 1502 --------ASALTLGLATAPSLSSSQ-----------TPGHPLLLAPTSSHVPGLNSTVA 1542 Query: 233 PSNEPNLKAENSAAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQ 292 P+ P L ++ A +P A LA + S S + + + Sbjct: 1543 PACSPVLVPASALASPFPSAPNPAP---------AQASLLAPASSASQALATPLAPMAAP 1593 Query: 293 LLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQ--SFIQQCVQQTSS 350 I A L +P P P L S + + P+S + + + Sbjct: 1594 --QTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAP 1651 Query: 351 DMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAP--------RTVSVQTLNPLAGP 402 V+A +T V + + S S +++ ++ A AP +T+S+ T NP GP Sbjct: 1652 TPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNP-QGP 1710 Query: 403 VGAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPL-VTSVANTVTTVSLQPEKPVVSGTA 461 + TL S+ P ++ T A T L PL T + L P PV A Sbjct: 1711 FPTQ----TL-SLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPA 1765 Query: 462 VTLSL-PAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQPAG 520 TL+L PA +S A++ P+ VQ P PV + Sbjct: 1766 HTLTLAPA-----SSSASLLAPA-------------------SVQTLTLSPAPVPTLGPA 1801 Query: 521 IPQAVQVKQLVVQQPSGGNEKQVTTISHSSTLTIQKCGQKTMPVNTI--IPTSQFPPASI 578 Q + + Q P+ S +S+L + G +PV + +P S+ P ++ Sbjct: 1802 AAQTLALAPASTQSPA----------SQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTL 1851 Score = 42.4 bits (98), Expect = 0.002 Identities = 50/226 (22%), Positives = 86/226 (38%), Gaps = 31/226 (13%) Query: 37 STPVALGAVTKAPVSVCVEPTASQPLR-SPVGTLVTKVAPVSAPPKVSSGPRLPAPQIVA 95 S P A+ A+ PVS V +A P+ PV L + P PP S P P Sbjct: 2449 SAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPP--CSSPACTPPPACT 2506 Query: 96 VKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVP---- 151 +T PP + + S PL+L P ++ + T + RP Sbjct: 2507 PPPAHTP----------PPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQ 2556 Query: 152 --ANPQTVKICTVPNSSSQLIKKVAVTPVKKLAQIGTTVVTTVPK-----PS----SVQS 200 A+P+++++ +V +S + +++ P K L + ++ K PS ++++ Sbjct: 2557 ALASPESLELASVASSET---SSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEA 2613 Query: 201 VAVPTSVVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLKAENSAA 246 ++P P T T+ P S L+ SAA Sbjct: 2614 GSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAA 2659 Score = 40.0 bits (92), Expect = 0.009 Identities = 53/197 (26%), Positives = 76/197 (38%), Gaps = 18/197 (9%) Query: 57 TASQPLRSPVGTLVTKVAP------VSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFPANL 110 T + P SP V + AP SAP + + +P V + APN TI L Sbjct: 2423 TTTPPRCSPARERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHIL 2482 Query: 111 QLPPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRPAVPANPQTVKICTVPNSSSQLI 170 PP I S P P T A T + P++P + +VP S+S Sbjct: 2483 PSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTN 2542 Query: 171 KKVAVTPVKKLAQIGTTVVTTVPKPSSVQSVAV---PTSVVTVTPGKPLNTVTT--LKPS 225 + + P +L + P S++ +V TS +++ P K L V L S Sbjct: 2543 LPLGLRPEAELC------AQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVS 2596 Query: 226 SLGASSTPSNEPNLKAE 242 S TPS P+L E Sbjct: 2597 EKNLSLTPS-APSLTLE 2612 Score = 38.9 bits (89), Expect = 0.021 Identities = 124/661 (18%), Positives = 219/661 (33%), Gaps = 127/661 (19%) Query: 1 MPAGLTEPAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSV----CVEP 56 +P L P G + + T+++ P PVR+ P + P++V P Sbjct: 1082 LPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPP 1141 Query: 57 TASQPLRSPVGTLVTKV--APVSAPPKVSSGP----RLPAPQIVAV-------------- 96 A+ + T T AP AP ++ P RLP+ ++V++ Sbjct: 1142 AAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANA 1201 Query: 97 KAPNTTTIQFPAN-LQLPPGTVLIKSNSGPLMLVSPQQTVTRAETTSNITSRP------- 148 T Q N L L V + P L + A ++ S+P Sbjct: 1202 GGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQ 1261 Query: 149 AVPANPQTVKICTVPNSSSQ--------------------LIKKVAVTP--VKKLAQIGT 186 AV P + +P+S+ ++ V V++ + G Sbjct: 1262 AVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGL 1321 Query: 187 TVV---TTVPKPSSVQSVAVPTSVVTVTPGK-----------PLNTVTTLKPSSLGASST 232 T V P+P S AV T+TPG+ P+ T T ++P L + Sbjct: 1322 TPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRP-LLKLVHS 1380 Query: 233 PSNEPNLKAENSAAVQIN-------------LSPTMLENVKKCKNFLAMLIKLACSGSQS 279 PS E + A +A + I+ SP + N + ++ + + S S Sbjct: 1381 PSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLP 1440 Query: 280 PEMGQNVKKLVEQLLDAKIEAEEFTRKLYVELKSSPQPHLVPFLKKSVVALRQLLPNSQS 339 + + L I A L +S P L P + + P S Sbjct: 1441 ISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAA--------PGPPS 1492 Query: 340 FIQQCVQQTSSDMVIATCTTTVTTSPVVTTTVSSSQSEKSIIVSGATAPRTVSV-QTLNP 398 ++S + + T ++SSSQ+ ++ T+ + T+ P Sbjct: 1493 LAPSGASPSASALTLGLAT---------APSLSSSQTPGHPLLLAPTSSHVPGLNSTVAP 1543 Query: 399 LAGPVGAKAGVV-----TLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPE 453 PV A + + + P A+ A + + PL A ++ P Sbjct: 1544 ACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPA 1603 Query: 454 KPVV-----------------SGTAVTLSLPAVTFGETSGAAICLPSVKPVVSSAGTTSD 496 P+ S T V + P+ T G + +A +P+ PV++ + T + Sbjct: 1604 PPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTM 1663 Query: 497 KPV-----IGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQQPSGGNEKQVTTISHSST 551 P + +P + P L+ G Q L P G Q +++ +S+ Sbjct: 1664 LPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASS 1723 Query: 552 L 552 L Sbjct: 1724 L 1724 >gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens] Length = 2382 Score = 52.0 bits (123), Expect = 2e-06 Identities = 114/475 (24%), Positives = 177/475 (37%), Gaps = 70/475 (14%) Query: 75 PVSAPPKVS-SGPRLPA--PQIVAVKAPNTTTIQFPANLQLPPGTVLIKSNSGPLMLVSP 131 P +APP S +GP P P + ++ TT T + + S P +S Sbjct: 1319 PNTAPPNFSHTGPTFPVVPPFLSSIAGVPTTAA----------ATAPVPATSSPPNDIS- 1367 Query: 132 QQTVTRAETTSNITSRPAVPANPQTVKICT---VPNSSSQLIKKVAVTPVKKLAQIGTTV 188 TS I S VP + T V S I V+ +PV T+ Sbjct: 1368 ---------TSVIQSEVTVPTEEGIAGVATSTGVVTSGGLPIPPVSESPVLSSVVSSITI 1418 Query: 189 VTTVPKPSSVQSVAVPTS----VVTVTPGKPLNTVTTLKPSSLGASSTPSNEPNLKAENS 244 V ++ S+ VPTS VV+ T P TV+ S+ G+++TP +P Sbjct: 1419 PAVVSISTTSPSLQVPTSTSEIVVSSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQ 1478 Query: 245 AAVQINLSPTMLENVKKCKNFLAMLIKLACSGSQSPEMGQNVKKLVEQLLDAKIEAEEFT 304 AA + T L +V +F + +L+ S S + +V + T Sbjct: 1479 AAGSTTVGAT-LTSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSST 1537 Query: 305 RKLYVELK-----SSP---------QPH-LVPFLKKSVVALRQLLPNSQSFIQQCVQQTS 349 L L SSP QP L P + SV+A +LP Q TS Sbjct: 1538 TGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILP-------QAAGPTS 1590 Query: 350 SDMV-----IATCTTTVTTSPVVTTTVSSSQSEKSIIVSGA-TAPRTVSVQTLNPLAGPV 403 + ++ I V P V T+ SQ + +++ + T V T G Sbjct: 1591 TPLLPQVPSIPPLVQPVANVPAVQQTLIHSQPQPALLPNQPHTHCPEVDSDTQPKAPGID 1650 Query: 404 GAKAGVVTLHSVGPTAATGGTTAGTGLLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVT 463 K L S+ ++ G + L+TS + ++V + T ++ P K + S T+ Sbjct: 1651 DIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTC 1710 Query: 464 LSLPAVTFGETSGAAICLPSVKPVVSSAGTTSDKPVIGTPVQIKLAQPGPVLSQP 518 L + G + LP V PVV+ ++ PV T +K PG S+P Sbjct: 1711 LPPTNLPLG-----TVALP-VTPVVTPGQVST--PVSTTTSGVK---PGTAPSKP 1754 Score = 39.3 bits (90), Expect = 0.016 Identities = 41/142 (28%), Positives = 62/142 (43%), Gaps = 12/142 (8%) Query: 8 PAGAAPPAAVSASGTVTMAPAGALPVRVESTPVALGAVTKAPVSVCVEPTAS--QPLRSP 65 P A P+ + S T T P LP+ + PV VT VS V T S +P +P Sbjct: 1693 PTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVT-PVVTPGQVSTPVSTTTSGVKPGTAP 1751 Query: 66 VGTLVTKVAPVSAPPKVSSGPRLPAPQIVAVKAPNTTTIQFP-----ANLQ--LPPGTVL 118 +TK + ++ +G LP+ Q+ P+ T Q P A L+ L P + Sbjct: 1752 SKPPLTKAPVLPVGTELPAG-TLPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSPEMIT 1810 Query: 119 IKSNSGPLMLVSPQQTVTRAET 140 + S GP+ + +P +T A T Sbjct: 1811 VTSAVGPVSMAAP-TAITEAGT 1831 Score = 35.0 bits (79), Expect = 0.30 Identities = 25/87 (28%), Positives = 36/87 (41%), Gaps = 9/87 (10%) Query: 35 VESTPVALGAVTKAPVSVCVEPTASQPLRSPVGTLVTKVAPVSAPPKVSSGPRLPA---- 90 + +T VA + + S C+ PT P+GT+ V PV P +VS+ Sbjct: 1692 IPTTAVAPSKLLTSTTSTCLPPT-----NLPLGTVALPVTPVVTPGQVSTPVSTTTSGVK 1746 Query: 91 PQIVAVKAPNTTTIQFPANLQLPPGTV 117 P K P T P +LP GT+ Sbjct: 1747 PGTAPSKPPLTKAPVLPVGTELPAGTL 1773 Score = 30.8 bits (68), Expect = 5.6 Identities = 48/207 (23%), Positives = 72/207 (34%), Gaps = 25/207 (12%) Query: 370 TVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAATGGTTAGTG 429 TV S Q S ++ +TVS + + A G G + + Sbjct: 654 TVDSGQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIP----------------ST 697 Query: 430 LLQTSKPLVTSVANTVTTVSLQPEKPVVSGTAVTLSLPAVTFGETSGAAICLPSVKPVVS 489 + S+P ++V Q + S T V+ S P + G P + V Sbjct: 698 VQAQSQPHGVYPPSSVAQGQSQGQPSSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQY 757 Query: 490 SAGTTSDKPVIGTPVQIKLAQPGPVLSQPAGIPQAVQVKQLVVQQ--PSGGNEKQVTTIS 547 S TS T + AQP P +PQ KQL V Q P+ E Q+ + Sbjct: 758 SLSQTS------TSSEATTAQPVSQPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVAT 811 Query: 548 HSSTLTIQKCGQKTMPVNTIIPTSQFP 574 S + + G +PV +PT P Sbjct: 812 QPSVVPVHS-GAHFLPVGQPLPTPLLP 837 Score = 30.0 bits (66), Expect = 9.6 Identities = 42/160 (26%), Positives = 70/160 (43%), Gaps = 18/160 (11%) Query: 368 TTTVSSSQSEKSIIVSGATAPRTVSVQTLNPLAGPVGAKAGVVTLHSVGPTAATGGTTAG 427 +TTV ++ + S S + +S+Q + + P A+ VV+ HS+ T+ + +T G Sbjct: 1482 STTVGATLTSVSTTTSFPSTASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHS--STTG 1539 Query: 428 TGLLQTSKPLVTSVANTVTTVSLQPE--KPVV--SGTAVTLSLPAVTFGETSGAAICLPS 483 ++ +S V++ QP P+V S A T LP ++ +PS Sbjct: 1540 LAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIPSVIASTPILPQAAGPTSTPLLPQVPS 1599 Query: 484 VKPVVSSAGTTSDKPVIGTP-VQIKLAQPGPVLSQPAGIP 522 + P+V +PV P VQ L P QPA +P Sbjct: 1600 IPPLV--------QPVANVPAVQQTLIHSQP---QPALLP 1628 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.126 0.343 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 32,207,991 Number of Sequences: 37866 Number of extensions: 1572039 Number of successful extensions: 11963 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 86 Number of HSP's successfully gapped in prelim test: 540 Number of HSP's that attempted gapping in prelim test: 7480 Number of HSP's gapped (non-prelim): 2556 length of query: 862 length of database: 18,247,518 effective HSP length: 111 effective length of query: 751 effective length of database: 14,044,392 effective search space: 10547338392 effective search space used: 10547338392 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.