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Search of human proteins with 148728188
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148728188 integrin, alpha E precursor [Homo sapiens]
(1179 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148728188 integrin, alpha E precursor [Homo sapiens] 2354 0.0
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] 417 e-116
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 416 e-116
gi|62548866 integrin, alpha D precursor [Homo sapiens] 405 e-113
gi|34452173 integrin alpha X precursor [Homo sapiens] 384 e-106
gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] 340 6e-93
gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] 318 1e-86
gi|52485853 integrin, alpha 11 precursor [Homo sapiens] 313 8e-85
gi|38569398 integrin, alpha 10 precursor [Homo sapiens] 310 7e-84
gi|116295258 integrin alpha 2 precursor [Homo sapiens] 300 7e-81
gi|31657142 integrin, alpha 1 precursor [Homo sapiens] 292 1e-78
gi|52485941 integrin, alpha 9 precursor [Homo sapiens] 207 4e-53
gi|67191027 integrin alpha 4 precursor [Homo sapiens] 187 4e-47
gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] 170 6e-42
gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] 170 6e-42
gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] 159 1e-38
gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] 159 1e-38
gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] 150 9e-36
gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [... 148 3e-35
gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [... 148 3e-35
gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] 146 1e-34
gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] 145 3e-34
gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] 145 3e-34
gi|56237029 integrin alpha 5 precursor [Homo sapiens] 144 4e-34
gi|49170034 integrin, alpha 8 [Homo sapiens] 142 2e-33
gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] 130 1e-29
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 95 4e-19
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 94 6e-19
gi|112734845 collagen, type XX, alpha 1 [Homo sapiens] 85 5e-16
gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens] 83 1e-15
>gi|148728188 integrin, alpha E precursor [Homo sapiens]
Length = 1179
Score = 2354 bits (6100), Expect = 0.0
Identities = 1179/1179 (100%), Positives = 1179/1179 (100%)
Query: 1 MWLFHTLLCIASLALLAAFNVDVARPWLTPKGGAPFVLSSLLHQDPSTNQTWLLVTSPRT 60
MWLFHTLLCIASLALLAAFNVDVARPWLTPKGGAPFVLSSLLHQDPSTNQTWLLVTSPRT
Sbjct: 1 MWLFHTLLCIASLALLAAFNVDVARPWLTPKGGAPFVLSSLLHQDPSTNQTWLLVTSPRT 60
Query: 61 KRTPGPLHRCSLVQDEILCHPVEHVPIPKGRHRGVTVVRSHHGVLICIQVLVRRPHSLSS 120
KRTPGPLHRCSLVQDEILCHPVEHVPIPKGRHRGVTVVRSHHGVLICIQVLVRRPHSLSS
Sbjct: 61 KRTPGPLHRCSLVQDEILCHPVEHVPIPKGRHRGVTVVRSHHGVLICIQVLVRRPHSLSS 120
Query: 121 ELTGTCSLLGPDLRPQAQANFFDLENLLDPDARVDTGDCYSNKEGGGEDDVNTARQRRAL 180
ELTGTCSLLGPDLRPQAQANFFDLENLLDPDARVDTGDCYSNKEGGGEDDVNTARQRRAL
Sbjct: 121 ELTGTCSLLGPDLRPQAQANFFDLENLLDPDARVDTGDCYSNKEGGGEDDVNTARQRRAL 180
Query: 181 EKEEEEDKEEEEDEEEEEAGTEIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECN 240
EKEEEEDKEEEEDEEEEEAGTEIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECN
Sbjct: 181 EKEEEEDKEEEEDEEEEEAGTEIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECN 240
Query: 241 FALVQYGGVIQTEFDLRDSQDVMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSR 300
FALVQYGGVIQTEFDLRDSQDVMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSR
Sbjct: 241 FALVQYGGVIQTEFDLRDSQDVMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSR 300
Query: 301 RKASKVMVVLTDGGIFEDPLNLTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASD 360
RKASKVMVVLTDGGIFEDPLNLTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASD
Sbjct: 301 RKASKVMVVLTDGGIFEDPLNLTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASD 360
Query: 361 PDETHAFKVTNYMALDGLLSKLRYNIISMEGTVGDALHYQLAQIGFSAQILDERQVLLGA 420
PDETHAFKVTNYMALDGLLSKLRYNIISMEGTVGDALHYQLAQIGFSAQILDERQVLLGA
Sbjct: 361 PDETHAFKVTNYMALDGLLSKLRYNIISMEGTVGDALHYQLAQIGFSAQILDERQVLLGA 420
Query: 421 VGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAEAAQYSYLGYAVAVLHKTCSLSYIAGA 480
VGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAEAAQYSYLGYAVAVLHKTCSLSYIAGA
Sbjct: 421 VGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAEAAQYSYLGYAVAVLHKTCSLSYIAGA 480
Query: 481 PRYKHHGAVFELQKEGREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYH 540
PRYKHHGAVFELQKEGREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYH
Sbjct: 481 PRYKHHGAVFELQKEGREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYH 540
Query: 541 VHGEEGRVYVYRLSEQDGSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAP 600
VHGEEGRVYVYRLSEQDGSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAP
Sbjct: 541 VHGEEGRVYVYRLSEQDGSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAP 600
Query: 601 LEGFGADDGASFGSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMAGGFDISGDGL 660
LEGFGADDGASFGSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMAGGFDISGDGL
Sbjct: 601 LEGFGADDGASFGSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMAGGFDISGDGL 660
Query: 661 ADITVGTLGQAVVFRSRPVVRLKVSMAFTPSALPIGFNGVVNVRLCFEISSVTTASESGL 720
ADITVGTLGQAVVFRSRPVVRLKVSMAFTPSALPIGFNGVVNVRLCFEISSVTTASESGL
Sbjct: 661 ADITVGTLGQAVVFRSRPVVRLKVSMAFTPSALPIGFNGVVNVRLCFEISSVTTASESGL 720
Query: 721 REALLNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQLCEDLLLMPTEGELCEEDCF 780
REALLNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQLCEDLLLMPTEGELCEEDCF
Sbjct: 721 REALLNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQLCEDLLLMPTEGELCEEDCF 780
Query: 781 SNASVKVSYQLQTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLATTVS 840
SNASVKVSYQLQTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLATTVS
Sbjct: 781 SNASVKVSYQLQTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLATTVS 840
Query: 841 QQELVVGLTKELTLNINLTNSGEDSYMTSMALNYPRNLQLKRMQKPPSPNIQCDDPQPVA 900
QQELVVGLTKELTLNINLTNSGEDSYMTSMALNYPRNLQLKRMQKPPSPNIQCDDPQPVA
Sbjct: 841 QQELVVGLTKELTLNINLTNSGEDSYMTSMALNYPRNLQLKRMQKPPSPNIQCDDPQPVA 900
Query: 901 SVLIMNCRIGHPVLKRSSAHVSVVWQLEENAFPNRTADITVTVTNSNERRSLANETHTLQ 960
SVLIMNCRIGHPVLKRSSAHVSVVWQLEENAFPNRTADITVTVTNSNERRSLANETHTLQ
Sbjct: 901 SVLIMNCRIGHPVLKRSSAHVSVVWQLEENAFPNRTADITVTVTNSNERRSLANETHTLQ 960
Query: 961 FRHGFVAVLSKPSIMYVNTGQGLSHHKEFLFHVHGENLFGAEYQLQICVPTKLRGLQVVA 1020
FRHGFVAVLSKPSIMYVNTGQGLSHHKEFLFHVHGENLFGAEYQLQICVPTKLRGLQVVA
Sbjct: 961 FRHGFVAVLSKPSIMYVNTGQGLSHHKEFLFHVHGENLFGAEYQLQICVPTKLRGLQVVA 1020
Query: 1021 VKKLTRTQASTVCTWSQERACAYSSVQHVEEWHSVSCVIASDKENVTVAAEISWDHSEEL 1080
VKKLTRTQASTVCTWSQERACAYSSVQHVEEWHSVSCVIASDKENVTVAAEISWDHSEEL
Sbjct: 1021 VKKLTRTQASTVCTWSQERACAYSSVQHVEEWHSVSCVIASDKENVTVAAEISWDHSEEL 1080
Query: 1081 LKDVTELQILGEISFNKSLYEGLNAENHRTKITVVFLKDEKYHSLPIIIKGSVGGLLVLI 1140
LKDVTELQILGEISFNKSLYEGLNAENHRTKITVVFLKDEKYHSLPIIIKGSVGGLLVLI
Sbjct: 1081 LKDVTELQILGEISFNKSLYEGLNAENHRTKITVVFLKDEKYHSLPIIIKGSVGGLLVLI 1140
Query: 1141 VILVILFKCGFFKRKYQQLNLESIRKAQLKSENLLEEEN 1179
VILVILFKCGFFKRKYQQLNLESIRKAQLKSENLLEEEN
Sbjct: 1141 VILVILFKCGFFKRKYQQLNLESIRKAQLKSENLLEEEN 1179
>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
Length = 1152
Score = 417 bits (1073), Expect = e-116
Identities = 305/1013 (30%), Positives = 504/1013 (49%), Gaps = 69/1013 (6%)
Query: 201 TEIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQ 260
++IA ++DGSGSI P DF+R K+F+S +M K + F+L+QY + F ++ Q
Sbjct: 149 SDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQL--KKSKTLFSLMQYSEEFRIHFTFKEFQ 206
Query: 261 DVMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPL 320
+ + V+ ITQ+ T TA+ ++ V+ +F ++G+R+ A K++VV+TDG F DPL
Sbjct: 207 NNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPL 266
Query: 321 NLTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASDPDETHAFKVTNYMALDGLLS 380
VI +GV R+ IGVG+ F+S ++ +ELN IAS P H F+V N+ AL + +
Sbjct: 267 GYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNFEALKTIQN 326
Query: 381 KLRYNIISMEGT---VGDALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALLYDTRS 437
+LR I ++EGT + ++++Q GFSA I LL VG++DW+GG LY T
Sbjct: 327 QLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGP-LLSTVGSYDWAGGVFLY-TSK 384
Query: 438 RRGRFLNQTAAAAADAEAAQYSYLGYAVAVLHKTCSLSYIAGAPRYKHHGAVFELQKEGR 497
+ F+N T + +A YLGYA A++ + S + GAPRY+H G V ++
Sbjct: 385 EKSTFINMTRVDSDMNDA----YLGYAAAIILRNRVQSLVLGAPRYQHIGLVAMFRQNTG 440
Query: 498 EASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEGRVYVYRLSEQD 557
++G Q+G+YFG+ LC VD+D +GSTD +L+ AP Y+ G+V V L
Sbjct: 441 MWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGR 500
Query: 558 GSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYI 617
+ +L G G RFG A+ +GD++ DKLTDVAIGAP G +D G+VY+
Sbjct: 501 ARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP----GEEDNR--GAVYL 554
Query: 618 YNG-HWDGLSASPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLGQAVVFRS 676
++G G+S S SQRI S ++P LQYFG S++GG D++ DGL D+TVG G ++ RS
Sbjct: 555 FHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRS 614
Query: 677 RPVVRLKVSMAFTPSALP----------IGFNGVVNVRLCFEI-SSVTTASESGLREALL 725
+PV+R+K M F P + + VR+C + S G ++++
Sbjct: 615 QPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVV 674
Query: 726 NFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQLCEDL-LLMPTEGELCEEDCFSNAS 784
+ L +D G+ R ++ ++ + +Q CE L L +P C ED S
Sbjct: 675 TYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPN----CIEDPVSPIV 730
Query: 785 VKVSYQL-QTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLA-TTVSQQ 842
+++++ L TP + +P+L + P+EK C N C +L + + +S
Sbjct: 731 LRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLD 790
Query: 843 ELVVGLTKELTLNINLTNSGEDSYMTSMALNYPRNLQ------LKRMQKPPSPNIQCDDP 896
LVVG +E + + + N GEDSY T + +P +L L+ + S + C+
Sbjct: 791 CLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESA 850
Query: 897 QPV---ASVLIMNCRIGHPVL-KRSSAHVSVVWQLEENAFPNRTADITVTVTNSNE--RR 950
++ +C I HP+ + S ++ + ++ A + VT+ N R
Sbjct: 851 SSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRT 910
Query: 951 SLANETHTLQFRHGFVAVLSK--PSIMYVN--TGQGLSHHKEFLFHVHGENLFGAEYQLQ 1006
+ L ++ V++ S Y+N + S + + V L
Sbjct: 911 NKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPISLV 970
Query: 1007 ICVPTKLRGLQVVAVKKLTRTQASTVCTWSQERACAYSS-VQHVEEWHSVSCVIA----- 1060
VP +L + ++T ++ + ++ER ++S + + + V+C IA
Sbjct: 971 FLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNCSIAVCQRI 1030
Query: 1061 ---------SDKENVTVAAEISWDHSEELLKDVTELQILGEISFNKSLYEGLNAENH--R 1109
++ N T+ +S+D + + + EI FN S++ L + R
Sbjct: 1031 QCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLPGQGAFVR 1090
Query: 1110 TKITVVFLKDEKYHSLPIIIKGSVGGLLVLIVILVILFKCGFFKRKYQQLNLE 1162
++ E + LP+I+ SVGGLL+L +I L+K GFFKR+Y+ + E
Sbjct: 1091 SQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDMMSE 1143
>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
Length = 1153
Score = 416 bits (1068), Expect = e-116
Identities = 306/1014 (30%), Positives = 505/1014 (49%), Gaps = 70/1014 (6%)
Query: 201 TEIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQ 260
++IA ++DGSGSI P DF+R K+F+S +M K + F+L+QY + F ++ Q
Sbjct: 149 SDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQL--KKSKTLFSLMQYSEEFRIHFTFKEFQ 206
Query: 261 DVMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPL 320
+ + V+ ITQ+ T TA+ ++ V+ +F ++G+R+ A K++VV+TDG F DPL
Sbjct: 207 NNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPL 266
Query: 321 NLTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASDPDETHAFKVTNYMALDGLLS 380
VI +GV R+ IGVG+ F+S ++ +ELN IAS P H F+V N+ AL + +
Sbjct: 267 GYEDVIPEADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNFEALKTIQN 326
Query: 381 KLRYNIISMEGT---VGDALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALLYDTRS 437
+LR I ++EGT + ++++Q GFSA I LL VG++DW+GG LY T
Sbjct: 327 QLREKIFAIEGTQTGSSSSFEHEMSQEGFSAAITSNGP-LLSTVGSYDWAGGVFLY-TSK 384
Query: 438 RRGRFLNQTAAAAADAEAAQYSYLGYAVAVLHKTCSLSYIAGAPRYKHHGAVFELQKEGR 497
+ F+N T + +A YLGYA A++ + S + GAPRY+H G V ++
Sbjct: 385 EKSTFINMTRVDSDMNDA----YLGYAAAIILRNRVQSLVLGAPRYQHIGLVAMFRQNTG 440
Query: 498 EASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEGRVYVYRLSE-Q 556
++G Q+G+YFG+ LC VD+D +GSTD +L+ AP Y+ G+V V L Q
Sbjct: 441 MWESNANVKGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGQ 500
Query: 557 DGSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVY 616
+ +L G G RFG A+ +GD++ DKLTDVAIGAP G +D G+VY
Sbjct: 501 RARWQCDAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAP----GEEDNR--GAVY 554
Query: 617 IYNG-HWDGLSASPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLGQAVVFR 675
+++G G+S S SQRI S ++P LQYFG S++GG D++ DGL D+TVG G ++ R
Sbjct: 555 LFHGTSGSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLR 614
Query: 676 SRPVVRLKVSMAFTPSALP----------IGFNGVVNVRLCFEI-SSVTTASESGLREAL 724
S+PV+R+K M F P + + VR+C + S G +++
Sbjct: 615 SQPVLRVKAIMEFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSV 674
Query: 725 LNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQLCEDL-LLMPTEGELCEEDCFSNA 783
+ + L +D G+ R ++ ++ + +Q CE L L +P C ED S
Sbjct: 675 VTYDLALDSGRPHSRAVFNETKNSTRRQTQVLGLTQTCETLKLQLPN----CIEDPVSPI 730
Query: 784 SVKVSYQL-QTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLA-TTVSQ 841
+++++ L TP + +P+L + P+EK C N C +L + + +S
Sbjct: 731 VLRLNFSLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSL 790
Query: 842 QELVVGLTKELTLNINLTNSGEDSYMTSMALNYPRNLQ------LKRMQKPPSPNIQCDD 895
LVVG +E + + + N GEDSY T + +P +L L+ + S + C+
Sbjct: 791 DCLVVGGPREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACES 850
Query: 896 PQPV---ASVLIMNCRIGHPVL-KRSSAHVSVVWQLEENAFPNRTADITVTVTNSNE--R 949
++ +C I HP+ + S ++ + ++ A + VT+ N R
Sbjct: 851 ASSTEVSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPR 910
Query: 950 RSLANETHTLQFRHGFVAVLSK--PSIMYVN--TGQGLSHHKEFLFHVHGENLFGAEYQL 1005
+ L ++ V++ S Y+N + S + + V L
Sbjct: 911 TNKTEFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPISL 970
Query: 1006 QICVPTKLRGLQVVAVKKLTRTQASTVCTWSQERACAYSS-VQHVEEWHSVSCVIA---- 1060
VP +L + ++T ++ + ++ER ++S + + + V+C IA
Sbjct: 971 VFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKERLPSHSDFLAELRKAPVVNCSIAVCQR 1030
Query: 1061 ----------SDKENVTVAAEISWDHSEELLKDVTELQILGEISFNKSLYEGLNAENH-- 1108
++ N T+ +S+D + + + EI FN S++ L +
Sbjct: 1031 IQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLPGQGAFV 1090
Query: 1109 RTKITVVFLKDEKYHSLPIIIKGSVGGLLVLIVILVILFKCGFFKRKYQQLNLE 1162
R++ E + LP+I+ SVGGLL+L +I L+K GFFKR+Y+ + E
Sbjct: 1091 RSQTETKVEPFEVPNPLPLIVGSSVGGLLLLALITAALYKLGFFKRQYKDMMSE 1144
>gi|62548866 integrin, alpha D precursor [Homo sapiens]
Length = 1161
Score = 405 bits (1042), Expect = e-113
Identities = 299/1011 (29%), Positives = 502/1011 (49%), Gaps = 78/1011 (7%)
Query: 202 EIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQD 261
+I ++DGSGSID DF + K F+ +M F + + FAL+QY +++ F +
Sbjct: 150 DIVFLIDGSGSIDQNDFNQMKGFVQAVMGQF--EGTDTLFALMQYSNLLKIHFTFTQFRT 207
Query: 262 VMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPLN 321
+ + V I Q+ +T TA+ + V+ +F +G+R+ A K+++V+TDG ++DPL
Sbjct: 208 SPSQQSLVDPIVQLKGLTFTATGILTVVTQLFHHKNGARKSAKKILIVITDGQKYKDPLE 267
Query: 322 LTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASDPDETHAFKVTNYMALDGLLSK 381
+ VI + G+ R+AIGVG F+ +ELN I+S P + H FKV N+ AL + +
Sbjct: 268 YSDVIPQAEKAGIIRYAIGVGHAFQGPTARQELNTISSAPPQDHVFKVDNFAALGSIQKQ 327
Query: 382 LRYNIISMEGT---VGDALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALLYDTRSR 438
L+ I ++EGT + ++++Q GFS + + + LGAVG+F WSGGA LY +
Sbjct: 328 LQEKIYAVEGTQSRASSSFQHEMSQEGFSTALTMDG-LFLGAVGSFSWSGGAFLYPP-NM 385
Query: 439 RGRFLNQTAAAAADAEAAQYSYLGYAVAVLHKTCSLSYIAGAPRYKHHGAVFELQKEGRE 498
F+N + + SYLGY+ + + + GAPRY+H G + R+
Sbjct: 386 SPTFINMSQENVDMRD----SYLGYSTELALWKGVQNLVLGAPRYQHTGKAVIFTQVSRQ 441
Query: 499 ASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEGRVYVYRLSEQDG 558
+ G Q+GSYFG+ LC VD+D DGSTD +L+ AP Y+ G+V V L
Sbjct: 442 WRKKAEVTGTQIGSYFGASLCSVDVDSDGSTDLILIGAPHYYEQTRGGQVSVCPLPRGRV 501
Query: 559 SFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIY 618
+ +L G G RFG A+ +GD+++DKL DVAIGAP + + G+VY++
Sbjct: 502 QWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAP------GEQENRGAVYLF 555
Query: 619 NGHWD-GLSASPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLGQAVVFRSR 677
+G + G+S S SQRI +S ++P LQYFG +++GG D++ DGL D+ VG GQ ++ RS
Sbjct: 556 HGASESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDLAVGARGQVLLLRSL 615
Query: 678 PVVRLKVSMAFT---------------PSALPIGFNGVVNVRLCFEISSVTTASESGLRE 722
PV+++ V+M F+ PSAL G + +C I ++ + G +
Sbjct: 616 PVLKVGVAMRFSPVEVAKAVYRCWEEKPSALEAG-----DATVCLTIQK-SSLDQLGDIQ 669
Query: 723 ALLNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQLCEDL-LLMPTEGELCEEDCFS 781
+ + F L +D G+ R ++ ++ R+ CE L LL+P C ED S
Sbjct: 670 SSVRFDLALDPGRLTSRAIFNETKNPTLTRRKTLGLGIHCETLKLLLPD----CVEDVVS 725
Query: 782 NASVKVSYQL-QTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLATTVS 840
+ +++ L + P + +P+L ++ LP+EK C C +L + + S
Sbjct: 726 PIILHLNFSLVREPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTLSFS 785
Query: 841 -QQELVVGLTKELTLNINLTNSGEDSYMTSMALNYPRNLQLKRM---QKPPSPN---IQC 893
Q L VG + EL + + + N+GEDSY T ++L YP L +R+ QK P + + C
Sbjct: 786 GLQTLTVGSSLELNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLAC 845
Query: 894 DD-PQPVASVLIMNCRIGHPVLKRSSAHVSVV-WQLEENAFPNRTADITVTVTNSNERRS 951
+ P + C + HP+ S +V + + A + + ++ N + S
Sbjct: 846 ETVPTEDEGLRSSRCSVNHPIFHEGSNGTFIVTFDVSYKATLGDRMLMRASASSENNKAS 905
Query: 952 LANETHTLQF--RHGFVAVLSK--PSIMYVN---TGQGLSHHKEFLFHVHGENLFGAEYQ 1004
+ T L+ ++ ++S+ S Y N + + E + V+ +
Sbjct: 906 SSKATFQLELPVKYAVYTMISRQEESTKYFNFATSDEKKMKEAEHRYRVNNLSQRDLAIS 965
Query: 1005 LQICVPTKLRGLQVVAVKKLTRTQASTVCTWSQERACAYSSVQHVEEWHSVSCVIA---- 1060
+ VP L G+ V V +Q S C ++ + + + C IA
Sbjct: 966 INFWVPVLLNGVAVWDVVMEAPSQ-SLPCVSERKPPQHSDFLTQISRSPMLDCSIADCLQ 1024
Query: 1061 ----------SDKENVTVAAEISWDHSEELLKDVTELQILGEISFNKSLYEGLNAEN--H 1108
++ + T+ +S+ E L+ + + EI+F+ S+Y L +
Sbjct: 1025 FRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAEITFDTSVYSQLPGQEAFM 1084
Query: 1109 RTKITVVFLKDEKYHSLPIIIKGSVGGLLVLIVILVILFKCGFFKRKYQQL 1159
R ++ +V +DE Y+++PII+ SVG LL+L +I L+K GFFKR Y+++
Sbjct: 1085 RAQMEMVLEEDEVYNAIPIIMGSSVGALLLLALITATLYKLGFFKRHYKEM 1135
Score = 34.7 bits (78), Expect = 0.55
Identities = 42/170 (24%), Positives = 68/170 (40%), Gaps = 22/170 (12%)
Query: 4 FHTLLCIASLALLAAFNVDVARPWLTPKGGAPFVLSSLLHQDPSTNQTWLLVTSPR---T 60
F T+L ++ LA FN+DV P + + F S + + L+V +P
Sbjct: 3 FGTVLLLSVLASYHGFNLDVEEPTIFQEDAGGFGQSVV-----QFGGSRLVVGAPLEVVA 57
Query: 61 KRTPGPLHRCSLVQDEILCHPVE-HV-PIPKGRHRGVTVVRSHHGV-LICIQVLVRRPHS 117
G L+ C+ +C P+ H+ P G+T+ S +G L+ + R
Sbjct: 58 ANQTGRLYDCAAATG--MCQPIPLHIRPEAVNMSLGLTLAASTNGSRLLACGPTLHRVCG 115
Query: 118 LSSELTGTCSLLG---------PDLRPQAQANFFDLENLLDPDARVDTGD 158
+S G+C LLG PD P+ D+ L+D +D D
Sbjct: 116 ENSYSKGSCLLLGSRWEIIQTVPDATPECPHQEMDIVFLIDGSGSIDQND 165
>gi|34452173 integrin alpha X precursor [Homo sapiens]
Length = 1163
Score = 384 bits (985), Expect = e-106
Identities = 300/1026 (29%), Positives = 509/1026 (49%), Gaps = 78/1026 (7%)
Query: 202 EIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQD 261
+I ++DGSGSI +F +F+ ++ F + F+L+Q+ QT F + +
Sbjct: 151 DIVFLIDGSGSISSRNFATMMNFVRAVISQFQRPSTQ--FSLMQFSNKFQTHFTFEEFRR 208
Query: 262 VMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPLN 321
L+ + ++ Q+ T TA+A+Q+V+ +F +S+G+RR A+K+++V+TDG D L+
Sbjct: 209 SSNPLSLLASVHQLQGFTYTATAIQNVVHRLFHASYGARRDAAKILIVITDGKKEGDSLD 268
Query: 322 LTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASDPDETHAFKVTNYMALDGLLSK 381
VI G+ R+AIGVG F++ + +ELN IAS P + H FKV ++ AL + ++
Sbjct: 269 YKDVIPMADAAGIIRYAIGVGLAFQNRNSWKELNDIASKPSQEHIFKVEDFDALKDIQNQ 328
Query: 382 LRYNIISMEG---TVGDALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALLYDTRSR 438
L+ I ++EG T + ++AQ GFSA + V LGAVG+F WSGGA LY +
Sbjct: 329 LKEKIFAIEGTETTSSSSFELEMAQEGFSAVFTPDGPV-LGAVGSFTWSGGAFLYPP-NM 386
Query: 439 RGRFLNQTAAAAADAEAAQYSYLGYAVAVLHKTCSLSYIAGAPRYKHHGAVFELQKEGRE 498
F+N + + + SYLGY+ + S + GAPRY+H G + R+
Sbjct: 387 SPTFINM----SQENVDMRDSYLGYSTELALWKGVQSLVLGAPRYQHTGKAVIFTQVSRQ 442
Query: 499 ASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEGRVYVYRLSEQDG 558
+ G Q+GSYFG+ LC VD+D DGSTD +L+ AP Y+ G+V V L
Sbjct: 443 WRMKAEVTGTQIGSYFGASLCSVDVDSDGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGWR 502
Query: 559 SFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIY 618
+ +L G G RFG A+ +GD++ DKLTDV IGAP G ++ G+VY++
Sbjct: 503 RWWCDAVLYGEQGHPWGRFGAALTVLGDVNGDKLTDVVIGAP----GEEENR--GAVYLF 556
Query: 619 NG-HWDGLSASPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLGQAVVFRSR 677
+G +S S SQRI S ++ LQYFG +++GG D++ DGL D+ VG GQ ++ R+R
Sbjct: 557 HGVLGPSISPSHSQRIAGSQLSSRLQYFGQALSGGQDLTQDGLVDLAVGARGQVLLLRTR 616
Query: 678 PVVRLKVSMAFTPSALP----------IGFNGVVNVRLCFEISSVTTASESGLREALLNF 727
PV+ + VSM F P+ +P + +V +C I + + G R+ +
Sbjct: 617 PVLWVGVSMQFIPAEIPRSAFECREQVVSEQTLVQSNICLYIDK-RSKNLLGSRDLQSSV 675
Query: 728 TLD--VDVGKQRRRLQCSDVRS-CLGCLREWSSGSQLCEDL-LLMPTEGELCEEDCFSNA 783
TLD +D G+ R + ++ L +R + CE+ LL+P+ C ED +
Sbjct: 676 TLDLALDPGRLSPRATFQETKNRSLSRVRVLGLKAH-CENFNLLLPS----CVEDSVTPI 730
Query: 784 SVKVSYQL-QTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLATTV-SQ 841
++++++ L P + +P+L + + LP+EK C C L ++ +
Sbjct: 731 TLRLNFTLVGKPLLAFRNLRPMLAADAQRYFTASLPFEKNCGADHICQDNLGISFSFPGL 790
Query: 842 QELVVGLTKELTLNINLTNSGEDSYMTSMALNYPRNLQLK------RMQKPPSPNIQCDD 895
+ L+VG EL + + N GEDSY T++ ++P L + + + S ++ CD
Sbjct: 791 KSLLVGSNLELNAEVMVWNDGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDS 850
Query: 896 PQPVAS--VLIMNCRIGHPVLKRSSAHVS--VVWQLEENAFPNRTADITVTVTNSNERRS 951
PV S +CRI H ++ R A ++ + + A +T V++ N
Sbjct: 851 -APVGSQGTWSTSCRINH-LIFRGGAQITFLATFDVSPKAVLGDRLLLTANVSSENNTPR 908
Query: 952 LANETHTLQF--RHGFVAVLS--KPSIMYVNTGQGLSHHKEFLFHVHGENLFGAE---YQ 1004
+ T L+ ++ V+S + Y+N + H + N G
Sbjct: 909 TSKTTFQLELPVKYAVYTVVSSHEQFTKYLNFSESEEKESHVAMHRYQVNNLGQRDLPVS 968
Query: 1005 LQICVPTKLRGLQVVAVKKLTRTQ-ASTVCTWSQERACAYSSVQHVEEWHSVSCVIA--- 1060
+ VP +L V +++ Q S C+ + A + H+++ + C IA
Sbjct: 969 INFWVPVELNQEAVWMDVEVSHPQNPSLRCSSEKIAPPASDFLAHIQKNPVLDCSIAGCL 1028
Query: 1061 -----------SDKENVTVAAEISWDHSEELLKDVTELQILGEISFNKSLYEGLNAEN-- 1107
++ + T+ +S+ ++L+ + + EI+F+ S+Y L +
Sbjct: 1029 RFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKKVSVVSVAEITFDTSVYSQLPGQEAF 1088
Query: 1108 HRTKITVVFLKDEKYHSLPIIIKGSVGGLLVLIVILVILFKCGFFKRKYQQLNLESIRKA 1167
R + T V K + ++ P+I+ S+GGLL+L +I +L+K GFFKR+Y+++ E+
Sbjct: 1089 MRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLALITAVLYKVGFFKRQYKEMMEEA--NG 1146
Query: 1168 QLKSEN 1173
Q+ EN
Sbjct: 1147 QIAPEN 1152
>gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]
Length = 1170
Score = 340 bits (871), Expect = 6e-93
Identities = 292/1024 (28%), Positives = 477/1024 (46%), Gaps = 115/1024 (11%)
Query: 198 EAGTEIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLR 257
+ ++ + DGS S+ P +FQ+ DF+ ++M+ ++ FA VQ+ +TEFD
Sbjct: 152 KGNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLSNTSYQ--FAAVQFSTSYKTEFDFS 209
Query: 258 DSQDVMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFE 317
D A ++++ + +T T A+ +V +F G+R A+KV++++TDG
Sbjct: 210 DYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDATKVLIIITDG---- 265
Query: 318 DPLNLTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASDPDETHAFKVTNYMALDG 377
T N + + R+ IG+G+ F++ + L+ AS P + + L
Sbjct: 266 ---EATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKFASKPASEFVKILDTFEKLKD 322
Query: 378 LLSKLRYNIISMEGTVGDAL---HYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALLYD 434
L ++L+ I +EGT L + +L+ G SA L ++GAVGA DW+GG L
Sbjct: 323 LFTELQKKIYVIEGTSKQDLTSFNMELSSSGISAD-LSRGHAVVGAVGAKDWAGGFLDLK 381
Query: 435 TRSRRGRFLNQTAAAAADAEAAQYSYLGYAVAVLHKTCSLSYIA-GAPRYKHHGAV--FE 491
+ F+ + YLGY V L S +A GAPRY+H G V F+
Sbjct: 382 ADLQDDTFIGNEPLTPE----VRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRVLLFQ 437
Query: 492 LQKEGREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEGRVYVY 551
+ G S + + G Q+GSYFG ELC VD+D DG T+ LL+ AP ++ GRV++Y
Sbjct: 438 EPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGGRVFIY 497
Query: 552 RLSEQDGSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGAS 611
+ + F L G PG+ RFG A+ A+ D++ D L DVA+GAPLE GA
Sbjct: 498 QRRQL--GFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQGA----- 550
Query: 612 FGSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLGQA 671
VYI+NG GLS PSQRI + V G+Q+FG S+ G D+ GDGLAD+ VG Q
Sbjct: 551 ---VYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQM 607
Query: 672 VVFRSRPVVRLKVSMAFTPSALPI-----------GFNGVVNVRLCFEISSVTTASESGL 720
+V SRPVV + M+F+P+ +P+ VN+ +CF+I S+ + G
Sbjct: 608 IVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQ-GR 666
Query: 721 REALLNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQLCEDLLLMPTEGELCEEDCF 780
A L +TL +D + RRR R L + S C D +C +D
Sbjct: 667 LVANLTYTLQLDGHRTRRRGLFPGGRHELR-RNIAVTTSMSCTDFSF---HFPVCVQDLI 722
Query: 781 SNASVKVSYQLQTPEG-------QTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAEL 833
S +V +++ L EG Q PIL R + +++P+EK C C A L
Sbjct: 723 SPINVSLNFSLWEEEGTPRDQRAQGKDIPPIL-RPSLHSETWEIPFEKNCGEDKKCEANL 781
Query: 834 QLA-TTVSQQELVVGLTKELTLNINLTNSGEDSYMTSMALNYPRNLQLKR--MQKPPSP- 889
+++ + + L + L++ ++L+N ED+Y + L++P L ++ M KP S
Sbjct: 782 RVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQI 841
Query: 890 NIQCDDPQPVASVL--IMNCRIGHPVLKRSSAHVSVVWQLEENAFPNR----TADITVTV 943
+ C++ + +L ++C + P+ K A SV Q+ N N + ++ V
Sbjct: 842 PVSCEELPEESRLLSRALSCNVSSPIFK---AGHSVALQMMFNTLVNSSWGDSVELHANV 898
Query: 944 TNSNERRSLANETHT-----LQFRHGFVAVLSKPSIMYVN-TGQGLSHHKEFLFHVHGEN 997
T +NE L + + + + + S +YV+ T +G H+ + H++
Sbjct: 899 TCNNEDSDLLEDNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQ--VKHMYQVR 956
Query: 998 LFGAEYQLQICVPTKLRGLQVVAVKKLTRTQASTVCTWSQER----ACAYSSVQHVEEWH 1053
+ + + I PT L+ V ++ WS + C Y ++ + +
Sbjct: 957 IQPSIHDHNI--PT----LEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAA 1010
Query: 1054 SVSCVIASDKENVTVAAEISWDHSEELLKDVTELQILGE--------------ISFNKSL 1099
A + V EI L++ + L+++GE ISFN S
Sbjct: 1011 EPCLPGALFRCPVVFRQEI-------LVQVIGTLELVGEIEASSMFSLCSSLSISFNSSK 1063
Query: 1100 YEGLNAENHR-----TKITVVFLKDEKYHSLPIIIKGSVGGLLVLIVILVILFKCGFFKR 1154
+ L N K+ VV+ K Y + + +GGLL+L++I ++L+K GFFKR
Sbjct: 1064 HFHLYGSNASLAQVVMKVDVVYEKQMLY----LYVLSGIGGLLLLLLIFIVLYKVGFFKR 1119
Query: 1155 KYQQ 1158
++
Sbjct: 1120 NLKE 1123
>gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]
Length = 1086
Score = 318 bits (816), Expect = 1e-86
Identities = 279/979 (28%), Positives = 453/979 (46%), Gaps = 110/979 (11%)
Query: 241 FALVQYGGVIQTEFDLRDSQDVMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSR 300
FA VQ+ +TEFD D A ++++ + +T T A+ +V +F G+R
Sbjct: 110 FAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGAR 169
Query: 301 RKASKVMVVLTDGGIFEDPLNLTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASD 360
A+KV++++TDG T N + + R+ IG+G+ F++ + L+ AS
Sbjct: 170 PDATKVLIIITDG-------EATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKFASK 222
Query: 361 PDETHAFKVTNYMALDGLLSKLRYNIISMEGTVGDAL---HYQLAQIGFSAQILDERQVL 417
P + + L L ++L+ I +EGT L + +L+ G SA L +
Sbjct: 223 PASEFVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISAD-LSRGHAV 281
Query: 418 LGAVGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAEAAQYSYLGYAVAVLHKTCSLSYI 477
+GAVGA DW+GG L + F+ + YLGY V L S +
Sbjct: 282 VGAVGAKDWAGGFLDLKADLQDDTFIGNEPLTPE----VRAGYLGYTVTWLPSRQKTSLL 337
Query: 478 A-GAPRYKHHGAV--FELQKEGREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLV 534
A GAPRY+H G V F+ + G S + + G Q+GSYFG ELC VD+D DG T+ LL+
Sbjct: 338 ASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLI 397
Query: 535 AAPFYHVHGEEGRVYVYRLSEQDGSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTD 594
AP ++ GRV++Y+ + F L G PG+ RFG A+ A+ D++ D L D
Sbjct: 398 GAPLFYGEQRGGRVFIYQRRQL--GFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVD 455
Query: 595 VAIGAPLEGFGADDGASFGSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMAGGFD 654
VA+GAPLE GA VYI+NG GLS PSQRI + V G+Q+FG S+ G D
Sbjct: 456 VAVGAPLEEQGA--------VYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKD 507
Query: 655 ISGDGLADITVGTLGQAVVFRSRPVVRLKVSMAFTPSALPI-----------GFNGVVNV 703
+ GDGLAD+ VG Q +V SRPVV + M+F+P+ +P+ VN+
Sbjct: 508 LEGDGLADVAVGAESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNI 567
Query: 704 RLCFEISSVTTASESGLREALLNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQLCE 763
+CF+I S+ + G A L +TL +D + RRR R L + S C
Sbjct: 568 TICFQIKSLIPQFQ-GRLVANLTYTLQLDGHRTRRRGLFPGGRHELR-RNIAVTTSMSCT 625
Query: 764 DLLLMPTEGELCEEDCFSNASVKVSYQLQTPEG-----QTDHPQPILDRYTEPFAIFQLP 818
D +C +D S +V +++ L EG + P + R + +++P
Sbjct: 626 DFSF---HFPVCVQDLISPINVSLNFSLWEEEGTPRDQRAGKDIPPILRPSLHSETWEIP 682
Query: 819 YEKACKNKLFCVAELQLA-TTVSQQELVVGLTKELTLNINLTNSGEDSYMTSMALNYPRN 877
+EK C C A L+++ + + L + L++ ++L+N ED+Y + L++P
Sbjct: 683 FEKNCGEDKKCEANLRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPG 742
Query: 878 LQLKR--MQKPPSP-NIQCDDPQPVASVL--IMNCRIGHPVLKRSSAHVSVVWQLEENAF 932
L ++ M KP S + C++ + +L ++C + P+ K A SV Q+ N
Sbjct: 743 LSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSSPIFK---AGHSVALQMMFNTL 799
Query: 933 PNR----TADITVTVTNSNERRSLANETHT-----LQFRHGFVAVLSKPSIMYVN-TGQG 982
N + ++ VT +NE L + + + + + S +YV+ T +G
Sbjct: 800 VNSSWGDSVELHANVTCNNEDSDLLEDNSATTIIPILYPINILIQDQEDSTLYVSFTPKG 859
Query: 983 LSHHKEFLFHVHGENLFGAEYQLQICVPTKLRGLQVVAVKKLTRTQASTVCTWSQER--- 1039
H+ + H++ + + + I PT L+ V ++ WS +
Sbjct: 860 PKIHQ--VKHMYQVRIQPSIHDHNI--PT----LEAVVGVPQPPSEGPITHQWSVQMEPP 911
Query: 1040 -ACAYSSVQHVEEWHSVSCVIASDKENVTVAAEISWDHSEELLKDVTELQILGE------ 1092
C Y ++ + + A + V EI L++ + L+++GE
Sbjct: 912 VPCHYEDLERLPDAAEPCLPGALFRCPVVFRQEI-------LVQVIGTLELVGEIEASSM 964
Query: 1093 --------ISFNKSLYEGLNAENHR-----TKITVVFLKDEKYHSLPIIIKGSVGGLLVL 1139
ISFN S + L N K+ VV+ K Y + + +GGLL+L
Sbjct: 965 FSLCSSLSISFNSSKHFHLYGSNASLAQVVMKVDVVYEKQMLY----LYVLSGIGGLLLL 1020
Query: 1140 IVILVILFKCGFFKRKYQQ 1158
++I ++L+K GFFKR ++
Sbjct: 1021 LLIFIVLYKVGFFKRNLKE 1039
>gi|52485853 integrin, alpha 11 precursor [Homo sapiens]
Length = 1188
Score = 313 bits (801), Expect = 8e-85
Identities = 293/1036 (28%), Positives = 469/1036 (45%), Gaps = 113/1036 (10%)
Query: 202 EIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQD 261
+I I+LDGS SI P + + F+ N+++ FY + +VQYG + EF L D +
Sbjct: 164 DIVIVLDGSNSIYP--WVEVQHFLINILKKFYIGPGQIQVGVVQYGEDVVHEFHLNDYRS 221
Query: 262 VMASLARVQNITQVGSV-TKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPL 320
V + +I Q G T+TA ++ F G R+ A KVM+V+TDG + P
Sbjct: 222 VKDVVEAASHIEQRGGTETRTAFGIEFARSEAF--QKGGRKGAKKVMIVITDGESHDSP- 278
Query: 321 NLTTVINSPKMQGVERFAIGV-----GEEFKSARTARELNLIASDPDETHAFKVTNYMAL 375
+L VI + V R+A+ V E+ IASDPD+ H F VT+ AL
Sbjct: 279 DLEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFLNEIKYIASDPDDKHFFNVTDEAAL 338
Query: 376 DGLLSKLRYNIISMEGTVGDALHY--QLAQIGFSAQILDERQVLLGAVGAFDWSGGALLY 433
++ L I S+EGT + + +++Q GFS+ ++++ VLLGAVGA+DW+ GA+L
Sbjct: 339 KDIVDALGDRIFSLEGTNKNETSFGLEMSQTGFSSHVVED-GVLLGAVGAYDWN-GAVLK 396
Query: 434 DTRSRRGRFLNQTAAAAADAEAAQY-SYLGYAV-AVLHKTCSLSYIAGAPRYKHHGAVFE 491
+T + + L ++ E + +YLGY V +V+ Y+AGAPR+ H G V
Sbjct: 397 ETSAGKVIPLRESYLKEFPEELKNHGAYLGYTVTSVVSSRQGRVYVAGAPRFNHTGKVIL 456
Query: 492 L-QKEGREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHG-EEGRVY 549
R + + G+Q+GSYFGSE+ VDID DG TD LLV AP Y G E G+VY
Sbjct: 457 FTMHNNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGVTDVLLVGAPMYFNEGRERGKVY 516
Query: 550 VYRLSEQDGSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDG 609
VY L + F L + NARFG ++A++ DL+QD DV +GAPLE A
Sbjct: 517 VYEL--RQNLFVYNGTLKDSHSYQNARFGSSIASVRDLNQDSYNDVVVGAPLEDNHA--- 571
Query: 610 ASFGSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLG 669
G++YI++G + +P QRI AS +A GLQYFG S+ G D++ DGL D+ VG LG
Sbjct: 572 ---GAIYIFHGFRGSILKTPKQRITASELATGLQYFGCSIHGQLDLNEDGLIDLAVGALG 628
Query: 670 QAVVFRSRPVVRLKVSMAFTPSALPIGFNG---------VVNVRLCFEISSVTTASESGL 720
AV+ SRPVV++ S+ F PS + I + LCF + ++
Sbjct: 629 NAVILWSRPVVQINASLHFEPSKINIFHRDCKRSGRDATCLAAFLCFTPIFLAPHFQTTT 688
Query: 721 REALLNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQLCEDLLLMPTEGELCEEDCF 780
N T+D R L R + SSG +LCE + L D
Sbjct: 689 VGIRYNATMDERRYTPRAHLDEGGDRFTNRAVL-LSSGQELCERI----NFHVLDTADYV 743
Query: 781 SNASVKVSYQLQTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQL----- 835
+ V Y L+ P DH P+LD +P+ C CV +L L
Sbjct: 744 KPVTFSVEYSLEDP----DH-GPMLDDGWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSD 798
Query: 836 --------------------ATTVSQQE---LVVGLTKELTLNINLTNSGEDSYMTSMAL 872
A T+S ++ + + + L N GE++Y T + +
Sbjct: 799 LPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNI 858
Query: 873 NYPRNLQLKRM-QKPPSP-NIQCDDPQPVASVLIMNCRIGHPVLK-RSSAHVSVVWQLEE 929
+ NLQ + QK S +I+C + + + C + +P + ++ + ++ +
Sbjct: 859 SQSANLQFASLIQKEDSDGSIECVNEERRLQKQV--CNVSYPFFRAKAKVAFRLDFEFSK 916
Query: 930 NAFPNRTADITVTVTNSNERRS------------LANETHTLQFRHGFVAVLSKPSIMYV 977
+ F + ++SNER S L E L R ++ +
Sbjct: 917 SIFLHHLEIELAAGSDSNERDSTKEDNVAPLRFHLKYEADVLFTRSSSLSHYEVKPNSSL 976
Query: 978 NTGQGLSHHKEFLFHVHGENLFGAE-YQLQICVPTKLR-GLQVVAVKKLTRTQASTVCT- 1034
G+ +F + LF ++I +P R G +++ ++ +A+T C
Sbjct: 977 ERYDGIGPPFSCIFRIQNLGLFPIHGMMMKITIPIATRSGNRLLKLRDFLTDEANTSCNI 1036
Query: 1035 WSQERACAYSSVQHVEEWHSVSCVIASDKENVTVAAEISWDHSEEL---------LKDVT 1085
W + Y E+ + S+ + V++ I ++E+ L+ +
Sbjct: 1037 WG--NSTEYRPTPVEEDLRRAPQLNHSNSDVVSINCNIRLVPNQEINFHLLGNLWLRSLK 1094
Query: 1086 ELQILG-EISFNKSLYEGLNA------ENHRTKITVVFLKDEKYH-SLPIIIKGSVGGLL 1137
L+ +I N +L ++ E+ +I K E + + II+ ++GGLL
Sbjct: 1095 ALKYKSMKIMVNAALQRQFHSPFIFREEDPSRQIVFEISKQEDWQVPIWIIVGSTLGGLL 1154
Query: 1138 VLIVILVILFKCGFFK 1153
+L ++++ L+K GFF+
Sbjct: 1155 LLALLVLALWKLGFFR 1170
>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
Length = 1167
Score = 310 bits (793), Expect = 7e-84
Identities = 249/761 (32%), Positives = 381/761 (50%), Gaps = 64/761 (8%)
Query: 202 EIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQD 261
++ I+LDGS SI P + + F+ ++ + + LVQYG E+ L D +
Sbjct: 167 DVVIVLDGSNSIYP--WSEVQTFLRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRT 224
Query: 262 VMASLARVQNITQ-VGSVTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPL 320
+ +N+++ G TKTA A+ F+ SHG R +A++++VV+TDG D
Sbjct: 225 KEEVVRAAKNLSRREGRETKTAQAIMVACTEGFSQSHGGRPEAARLLVVVTDGES-HDGE 283
Query: 321 NLTTVINSPKMQGVERFAIGV-GEEFKSARTA----RELNLIASDPDETHAFKVTNYMAL 375
L + + + V R+ I V G + R RE+ IASDPDE F VT+ AL
Sbjct: 284 ELPAALKACEAGRVTRYGIAVLGHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEAAL 343
Query: 376 DGLLSKLRYNIISMEGTVGD---ALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALL 432
++ L I +EG+ + + +++QIGFS L + +L G VGA+DW G L
Sbjct: 344 TDIVDALGDRIFGLEGSHAENESSFGLEMSQIGFSTHRLKDG-ILFGMVGAYDWGGSVLW 402
Query: 433 YDTRSRRGRFLNQTAAAAADAEAAQY--SYLGYAVA-VLHKTCSLSYIAGAPRYKHHGAV 489
+ R F + A A Q +YLGY+V+ +L + +++GAPR++H G V
Sbjct: 403 LEGGHRL--FPPRMALEDEFPPALQNHAAYLGYSVSSMLLRGGRRLFLSGAPRFRHRGKV 460
Query: 490 --FELQKEGREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFY--HVHGEE 545
F+L+K+G L+GEQ+GSYFGSELCP+D D DG+TD LLVAAP + + E
Sbjct: 461 IAFQLKKDGA-VRVAQSLQGEQIGSYFGSELCPLDTDRDGTTDVLLVAAPMFLGPQNKET 519
Query: 546 GRVYVYRLSEQDGSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFG 605
GRVYVY + +Q +L L P +ARFGFAM A+ DL+QD DVA+GAPLE
Sbjct: 520 GRVYVYLVGQQS-LLTLQGTLQPEPP-QDARFGFAMGALPDLNQDGFADVAVGAPLE--- 574
Query: 606 ADDGASFGSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITV 665
DG G++Y+Y+G G+ P+QRI A+++ L YFG S+ G D+ GD L D+ V
Sbjct: 575 --DGHQ-GALYLYHGTQSGVRPHPAQRIAAASMPHALSYFGRSVDGRLDLDGDDLVDVAV 631
Query: 666 GTLGQAVVFRSRPVVRLKVSMAFTPSALPI--------GFNGV-VNVRLCFEISSVTTAS 716
G G A++ SRP+V L S+ TP A+ + G V + LCF+++S T
Sbjct: 632 GAQGAAILLSSRPIVHLTPSLEVTPQAISVVQRDCRRRGQEAVCLTAALCFQVTSRTPGR 691
Query: 717 ESGLREALLNFTLDVDVGKQRRRLQCSDVRSCLGCLR-EWSSGSQLCEDLLLMPTEGELC 775
+ + FT +D R L R S G+ CE L L
Sbjct: 692 WD--HQFYMRFTASLDEWTAGARAAFDGSGQRLSPRRLRLSVGNVTCEQLHF----HVLD 745
Query: 776 EEDCFSNASVKVSYQLQTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQL 835
D ++ V++ L T P P+L+ + +P+ K C CV +L L
Sbjct: 746 TSDYLRPVALTVTFALD----NTTKPGPVLNEGSPTSIQKLVPFSKDCGPDNECVTDLVL 801
Query: 836 ATTVSQQE------LVVGLTKELTLNINLTNSGEDSYMTSMALNYPRNLQLKRM--QKPP 887
+ + +V G +++ ++ L N E++Y TS++L + RNL L + Q+
Sbjct: 802 QVNMDIRGSRKAPFVVRGGRRKVLVSTTLENRKENAYNTSLSLIFSRNLHLASLTPQRES 861
Query: 888 SPNIQCDDPQPVASVLIMNCRIGHPVLKRSSAHVSVVWQLE 928
++C P A + C +GHPV ++ A V+ + + E
Sbjct: 862 PIKVECAAPSAHARL----CSVGHPVF-QTGAKVTFLLEFE 897
Score = 30.8 bits (68), Expect = 8.0
Identities = 15/32 (46%), Positives = 22/32 (68%)
Query: 1124 SLPIIIKGSVGGLLVLIVILVILFKCGFFKRK 1155
SL I+I +GGLL+L +++ L+K GFF K
Sbjct: 1122 SLWILIGSVLGGLLLLALLVFCLWKLGFFAHK 1153
>gi|116295258 integrin alpha 2 precursor [Homo sapiens]
Length = 1181
Score = 300 bits (767), Expect = 7e-81
Identities = 224/739 (30%), Positives = 352/739 (47%), Gaps = 51/739 (6%)
Query: 202 EIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQD 261
++ ++ D S SI P D K+F+ ++ + L+QY + F+L +
Sbjct: 174 DVVVVCDESNSIYPWD--AVKNFLEKFVQGLDIGPTKTQVGLIQYANNPRVVFNLNTYKT 231
Query: 262 VMASLARVQNITQVGS-VTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPL 320
+ +Q G +T T A+Q+ ++++ G RR A+KVMVV+TDG + +
Sbjct: 232 KEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGRRSATKVMVVVTDGESHDGSM 291
Query: 321 NLTTVINSPKMQGVERFAIGV-----GEEFKSARTARELNLIASDPDETHAFKVTNYMAL 375
L VI+ + RF I V + +E+ IAS P E + F V++ AL
Sbjct: 292 -LKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKEIKAIASIPTERYFFNVSDEAAL 350
Query: 376 DGLLSKLRYNIISMEGTV--GDALHYQLAQIGFSAQILDERQVL-LGAVGAFDWSGGALL 432
L I S+EGTV GD +++Q+GFSA + +L LGAVGAF WSG +
Sbjct: 351 LEKAGTLGEQIFSIEGTVQGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTIV- 409
Query: 433 YDTRSRRGRFLNQTAAAAADAEAAQYS-YLGYAVAVLHKTCSLSYIAGAPRYKHHGAVFE 491
++ G + A + +S YLGY+VA + S ++AGAPR + G +
Sbjct: 410 --QKTSHGHLIFPKQAFDQILQDRNHSSYLGYSVAAISTGESTHFVAGAPRANYTGQIVL 467
Query: 492 LQ-KEGREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFY--HVHGEEGRV 548
E + + G+Q+GSYFGS LC VD+D D TD LLV AP Y + EEGRV
Sbjct: 468 YSVNENGNITVIQAHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRV 527
Query: 549 YVYRLSEQDGSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADD 608
Y++ + E G + L G G N RFG A+AA+ D++ D DV +G+PLE
Sbjct: 528 YLFTIKE--GILGQHQFLEGPEGIENTRFGSAIAALSDINMDGFNDVIVGSPLE------ 579
Query: 609 GASFGSVYIYNGHWDGLSASPSQRIRASTVA--PGLQYFGMSMAGGFDISGDGLADITVG 666
+ G+VYIYNGH + SQ+I S A LQYFG S+ G D++GD + D+++G
Sbjct: 580 NQNSGAVYIYNGHQGTIRTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIG 639
Query: 667 TLGQAVVFRSRPVVRLKVSMAFTPSALP-IGFNGVVNVRLCFEISSVTTASESGLREALL 725
GQ V S+ + + + +FTP + + N + ++LCF T + + +
Sbjct: 640 AFGQVVQLWSQSIADVAIEASFTPEKITLVNKNAQIILKLCFSAKFRPTKQNNQV-AIVY 698
Query: 726 NFTLDVDVGKQRRRLQCSDVRSCLGCLRE--WSSGSQLCEDLLLMPTEGELCEEDCFSNA 783
N TLD D R + + CL++ + +Q C + ++ E D ++
Sbjct: 699 NITLDADGFSSRVTSRGLFKENNERCLQKNMVVNQAQSCPEHIIYIQE----PSDVVNSL 754
Query: 784 SVKVSYQLQTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAEL-----QLATT 838
++V L+ P P L+ Y+E +F +P+ K C C+++L Q+
Sbjct: 755 DLRVDISLENP-----GTSPALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAA 809
Query: 839 VSQQELVVGLTKELTLNINLTNSGEDSYMTSMALNYPRNLQLKRMQKP-PSPNIQCDDPQ 897
Q +V K LT ++ L N E +Y T + +++ NL P + C Q
Sbjct: 810 QEQPFIVSNQNKRLTFSVTLKNKRESAYNTGIVVDFSENLFFASFSLPVDGTEVTC---Q 866
Query: 898 PVASVLIMNCRIGHPVLKR 916
AS + C +G+P LKR
Sbjct: 867 VAASQKSVACDVGYPALKR 885
Score = 43.5 bits (101), Expect = 0.001
Identities = 21/68 (30%), Positives = 43/68 (63%), Gaps = 5/68 (7%)
Query: 1094 SFNKSLYEGLNAENHRTKITVVFLKDEKYHSLP--IIIKGSVGGLLVLIVILVILFKCGF 1151
++N +Y E++ I ++ +K ++ +P +II + G+L+L+ ++ IL+K GF
Sbjct: 1102 TYNPEIYV---IEDNTVTIPLMIMKPDEKAEVPTGVIIGSIIAGILLLLALVAILWKLGF 1158
Query: 1152 FKRKYQQL 1159
FKRKY+++
Sbjct: 1159 FKRKYEKM 1166
>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
Length = 1179
Score = 292 bits (748), Expect = 1e-78
Identities = 276/1040 (26%), Positives = 465/1040 (44%), Gaps = 127/1040 (12%)
Query: 202 EIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQD 261
+I I+LDGS SI P D A F+++++ + +VQYG + EF+L
Sbjct: 172 DIVIVLDGSNSIYPWDSVTA--FLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSS 229
Query: 262 VMASLARVQNITQVGS-VTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPL 320
L + I Q G T TA + FT + G+RR KVMV++TDG D
Sbjct: 230 TEEVLVAAKKIVQRGGRQTMTALGIDTARKEAFTEARGARRGVKKVMVIVTDGE-SHDNH 288
Query: 321 NLTTVINSPKMQGVERFAIGVGEEF-----KSARTARELNLIASDPDETHAFKVTNYMAL 375
L VI + + ++RF+I + + + + E+ IAS+P E H F V++ +AL
Sbjct: 289 RLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELAL 348
Query: 376 DGLLSKLRYNIISMEGTVGD---ALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALL 432
++ L I ++E T + +++Q GFSA + V+LGAVGA+DW+G ++
Sbjct: 349 VTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAH-YSQDWVMLGAVGAYDWNGTVVM 407
Query: 433 YDTRS---RRGRFLNQTAAAAADAEAAQYSYLGYAV-AVLHKTCSLSYIAGAPRYKHHGA 488
R N + + A SYLGY V + + + YIAG PRY H G
Sbjct: 408 QKASQIIIPRNTTFNVESTKKNEPLA---SYLGYTVNSATASSGDVLYIAGQPRYNHTGQ 464
Query: 489 VFELQKEGREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFY--HVHGEEG 546
V + E L L GEQ+GSYFGS L DID D +TD LLV AP Y E+G
Sbjct: 465 VIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQG 524
Query: 547 RVYVYRLSEQ--DGSFSLARILS------GHPGFT--------NARFGFAMAAMGDLSQD 590
+VYVY L++ + SL I H T ARFG A+AA+ DL+ D
Sbjct: 525 KVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLD 584
Query: 591 KLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMA 650
D+ IGAPLE D G G+VYIY+G + +QRI + L++FG S+
Sbjct: 585 GFNDIVIGAPLED---DHG---GAVYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIH 638
Query: 651 GGFDISGDGLADITVGTLGQAVVFRSRPVVRLKVSMAFTPSALPIGFNG---------VV 701
G D++GDGL D+T+G LG A +F SR V +KV+M F P+ + I +
Sbjct: 639 GEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCI 698
Query: 702 NVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQL 761
N +CF++ + E + EA L + + +D +Q R S + R+ +
Sbjct: 699 NATVCFDVK--LKSKEDTIYEADLQYRVTLDSLRQISRSFFSGTQE-----RKVQRNITV 751
Query: 762 CEDLLLMPTEGELCEEDCFSNASVKVSYQLQTPEGQTDHPQPILDRYTEPFAIFQLPYEK 821
+ + L + D + + + + L PE P+LD +P+ K
Sbjct: 752 RKSECTKHSFYMLDKHDFQDSVRITLDFNLTDPEN-----GPVLDDSLPNSVHEYIPFAK 806
Query: 822 ACKNKLFCVAELQLATTVSQQELVVGLTKELTLNINLT--NSGEDSYMTSMALNYPRNLQ 879
C NK C+++L L ++++L++ ++ N++LT N+ + +Y T ++Y NL
Sbjct: 807 DCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLV 866
Query: 880 LKRMQKPPSPNIQCDDPQPVASVLIMNCRIGHPVLKRSSAHVSVVWQLEENAFPNRTADI 939
++ IQ D + ++ C++G+P L+R + ++ I
Sbjct: 867 FSGIEA-----IQKDSCESNHNI---TCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTI 918
Query: 940 TVTVTNSNER------RSLANETHTLQFRHGF----------VAVLSKPSI-MYVNTGQG 982
++ T+ +E ++ N + +++ G +++ + ++ +N+ +
Sbjct: 919 YLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAANETVPEVINSTED 978
Query: 983 LSHHKEFLFHVHGENLFG-AEYQLQICVPTKL-RGLQVVAVKKLTRTQASTVCTWSQERA 1040
+ + + + F E +L I P G V+ L+ ++ + E
Sbjct: 979 IGNEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDP 1038
Query: 1041 CAY-------SSVQHVEEWHSVSCVIASDKENVTVAAEISWDHSEELLKDVTELQILGEI 1093
+ +S H++ + C N A I+ + + + V IL +
Sbjct: 1039 FSINSGKKMTTSTDHLKRGTILDC-------NTCKFATITCNLTSSDISQVNVSLILWKP 1091
Query: 1094 SFNKSLYEGLN-----------------AENHRTKITVVFLKDEKYHSLP--IIIKGSVG 1134
+F KS + LN + N + ++ + KD +P +I+ +
Sbjct: 1092 TFIKSYFSSLNLTIRGELRSENASLVLSSSNQKRELAIQISKDGLPGRVPLWVILLSAFA 1151
Query: 1135 GLLVLIVILVILFKCGFFKR 1154
GLL+L+++++ L+K GFFKR
Sbjct: 1152 GLLLLMLLILALWKIGFFKR 1171
>gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
Length = 1035
Score = 207 bits (528), Expect = 4e-53
Identities = 232/862 (26%), Positives = 379/862 (43%), Gaps = 156/862 (18%)
Query: 408 AQILDERQVLLGAVGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAEAAQYSYLGYAVAV 467
A E V++GA G+F W+G + + LN +Y+YLGYAV
Sbjct: 199 AGFFTEELVVMGAPGSFYWAGTIKVLNLTDNTYLKLNDEVIMNR-----RYTYLGYAVTA 253
Query: 468 LHKT--CSLSYIAGAPRYKHHGAVFELQKEGREASFLPVLE--GEQMGSYFGSELCPVDI 523
H + ++ + GAP+ K G V+ + + R + + + + G++MGSYFGS LC VD+
Sbjct: 254 GHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDL 313
Query: 524 DMDGSTDFLLVAAPFYHVHGEEGRVYVYRLSEQDGSFSLARILSGHPGFTNARFGFAMAA 583
+ DG +D LLV AP + +EG+V VY ++ +G+ L+G G NA FG ++A+
Sbjct: 314 NGDGLSD-LLVGAPMFSEIRDEGQVTVY-INRGNGALEEQLALTGD-GAYNAHFGESIAS 370
Query: 584 MGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSASPSQRIRASTVAPGLQ 643
+ DL D DVAIGAP E DD A G+VYIY+G G+ S ++ + P L+
Sbjct: 371 LDDLDNDGFPDVAIGAPKE----DDFA--GAVYIYHGDAGGIVPQYSMKLSGQKINPVLR 424
Query: 644 YFGMSMAGGFDISGDGLADITVGTL--GQAVVFRSRPVVRLKVSMAFTPSALPI------ 695
FG S++GG D+ G+G D+TVG V+ R+RPV+ + VS+ F P ++ I
Sbjct: 425 MFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDVSI-FLPGSINITAPQCH 483
Query: 696 -GFNGV--VNVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRRLQCSDVRSCLGCL 752
G V +NV CF E G LN+ L DV K+ + LG
Sbjct: 484 DGQQPVNCLNVTTCFSFHGKHVPGEIG-----LNYVLMADVAKKEKGQMPRVYFVLLG-- 536
Query: 753 REWSSGSQLCEDLLLMPTEGELCE----------EDCFSNASVKVSYQLQ---TPEGQTD 799
+ Q+ E L L E E C +D S + +Y L T E + +
Sbjct: 537 ---ETMGQVTEKLQLTYME-ETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEERE 592
Query: 800 HP--QPILDRYTEPFAIF---QLPYEKACKNKLFCVAELQLATTV---SQQE----LVVG 847
P P+L R+ + I Q +E+ C+++ C A+LQL + S E L +G
Sbjct: 593 LPPLTPVL-RWKKGQKIAQKNQTVFERNCRSE-DCAADLQLQGKLLLSSMDEKTLYLALG 650
Query: 848 LTKELTLNINLTNSGEDSYMTSMALNYPRNLQLKRMQKPPSPNIQCDDPQPVASVLIMNC 907
K ++LNI+++N G+D+Y +++ N R L M + I C+ + + C
Sbjct: 651 AVKNISLNISISNLGDDAYDANVSFNVSRELFFINMWQKEEMGISCE----LLESDFLKC 706
Query: 908 RIGHPVLK-RSSAHVSVVWQLEENAFPNRTADITVTVTNSNERRSLANETHTLQFRHGFV 966
+G P ++ +S SV++ + VT + N RS + +TL
Sbjct: 707 SVGFPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTL------- 759
Query: 967 AVLSKPSIMYVNTG-QGLSHHKEFLFHVHGENLFGAEY----QLQICVPTKLRGLQVVAV 1021
VL P + V+T G+ F V+GE++ A + L+ LQV
Sbjct: 760 -VLMVPLMHEVDTSITGIMSPTSF---VYGESVDAANFIQLDDLECHFQPINITLQVYNT 815
Query: 1022 KKLTRTQASTVCTWSQERACAYSSVQHVEEW-------------HSVSCVIASDKENV-- 1066
T +S ++ + + + HV+E + C+I ++EN+
Sbjct: 816 GPSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQEQENIFH 875
Query: 1067 -------------------------------TVAAEISWD-------HSEELLKD---VT 1085
+A E S ++E L KD V
Sbjct: 876 TIFAFFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVI 935
Query: 1086 ELQILGEISFNKSLYEGLNAENHRTKITVVFLKDEKYHSLP--------IIIKGSVGGLL 1137
+ ++ + +L A + ++TVVF E H+L II + G+L
Sbjct: 936 QFMSRAKVKVDPALRVVEIAHGNPEEVTVVF---EALHNLEPRGYVVGWIIAISLLVGIL 992
Query: 1138 VLIVILVILFKCGFFKRKYQQL 1159
+ +++ V+L+K GFF+R+Y+++
Sbjct: 993 IFLLLAVLLWKMGFFRRRYKEI 1014
>gi|67191027 integrin alpha 4 precursor [Homo sapiens]
Length = 1032
Score = 187 bits (476), Expect = 4e-47
Identities = 213/846 (25%), Positives = 369/846 (43%), Gaps = 132/846 (15%)
Query: 416 VLLGAVGAFDWSGGALLYD-TRSRRGRFLNQTAAAAADAEAAQYSYLGYAVAVLH--KTC 472
+++GA G+ W+G +Y+ T ++ FL++ + SYLGY+V H
Sbjct: 211 IVMGAPGSSYWTGSLFVYNITTNKYKAFLDK------QNQVKFGSYLGYSVGAGHFRSQH 264
Query: 473 SLSYIAGAPRYKHHGAVFELQKEGREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFL 532
+ + GAP+++ G + + +E + L ++G+++GSYFG+ +C VD++ DG +D L
Sbjct: 265 TTEVVGGAPQHEQIGKAYIFSIDEKELNILHEMKGKKLGSYFGASVCAVDLNADGFSD-L 323
Query: 533 LVAAPFYHVHGEEGRVYVYRLSEQDGSF--SLARILSGHPGFTNARFGFAMAAMGDLSQD 590
LV AP EEGRV+VY ++ G+ ++ L G + ARFG ++ +GD+ D
Sbjct: 324 LVGAPMQSTIREEGRVFVY-INSGSGAVMNAMETNLVGSDKYA-ARFGESIVNLGDIDND 381
Query: 591 KLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMA 650
DVAIGAP E DD G++YIYNG DG+S++ SQRI ++ L FG S++
Sbjct: 382 GFEDVAIGAPQE----DDLQ--GAIYIYNGRADGISSTFSQRIEGLQISKSLSMFGQSIS 435
Query: 651 GGFDISGDGLADITVGTL--GQAVVFRSRPVVRLKVSMAFTPSALPIGFNGV-------- 700
G D +G D+ VG AV+ R+RPVV + S++ S F+ V
Sbjct: 436 GQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLSHPESVNRTKFDCVENGWPSVC 495
Query: 701 VNVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQ 760
+++ LCF S G N +LDV+ R S R S+G+
Sbjct: 496 IDLTLCF---SYKGKEVPGYIVLFYNMSLDVN------RKAESPPRFYFS-----SNGTS 541
Query: 761 --LCEDLLLMPTEGELCEEDCFSNASVK-VSYQLQTPEGQTDHPQPILDRYTEPF----A 813
+ + + E F V+ + +Q P I R TE F
Sbjct: 542 DVITGSIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQP 601
Query: 814 IFQLPYEKACKNKLF----------CVAELQLATTV-------SQQELVVGLTKELTLNI 856
I Q EK K C A+LQ++ + ++ L VG K L LN+
Sbjct: 602 ILQQKKEKDIMKKTINFARFCAHENCSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNV 661
Query: 857 NLTNSGEDSYMTSMALNYPRNLQLKRMQKPPSPNIQCDDPQPVASVLIMNCRIGHPVLKR 916
+L N+G+D+Y T++ + P L ++ + I C+ + V+ ++C IG+ +
Sbjct: 662 SLFNAGDDAYETTLHVKLPVGLYFIKILELEEKQINCEVTDN-SGVVQLDCSIGYIYVDH 720
Query: 917 SSAHVSVVWQLEENAFPNRTADITVTV----TNSNERRSLANETHTLQFR---------H 963
S + + + L+ ++ D+++TV N E +L + T+ H
Sbjct: 721 LS-RIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVH 779
Query: 964 GFVAVLSKPSIMYVNTGQG-----LSHHKEFLFHV-HGENLFGAEYQLQICVPTKLRGLQ 1017
GFV + S +Y + + + FHV + N ++I VP Q
Sbjct: 780 GFV---NPTSFVYGSNDENEPETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSF-SPQ 835
Query: 1018 VVAVKKLTRTQAST----------VCTWSQERACAYSSVQHVEEWHSVS----------- 1056
+ + Q +T VC Q+++ A +++ + + S +
Sbjct: 836 TDKLFNILDVQTTTGECHFENYQRVCALEQQKS-AMQTLKGIVRFLSKTDKRLLYCIKAD 894
Query: 1057 -------CVIASDKENVTVAAEISWDHSEELLK-DVT-----ELQILGEISFNKSLYEGL 1103
C + + I + +L+ D T E++ G N + E L
Sbjct: 895 PHCLNFLCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGFPEPNPRVIE-L 953
Query: 1104 NAENHRTKITVVFLKDEK---YHSLPIIIKGSVGGLLVLIVILVILFKCGFFKRKYQQLN 1160
N + + + + L ++ Y ++ II + GL+VL++I +++K GFFKR+Y+ +
Sbjct: 954 NKDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSIL 1013
Query: 1161 LESIRK 1166
E R+
Sbjct: 1014 QEENRR 1019
>gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
Length = 1051
Score = 170 bits (431), Expect = 6e-42
Identities = 162/593 (27%), Positives = 276/593 (46%), Gaps = 70/593 (11%)
Query: 395 DALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAE 454
D L + Q+G S + V GA GA++W G + + + + + + D E
Sbjct: 190 DYLETGMCQLGTSGGFT-QNTVYFGAPGAYNWKGNSYMIQRKE-----WDLSEYSYKDPE 243
Query: 455 AAQYSYLGYAVAV----LHKTCSLSYIAGAPRYKHHGAVFELQKE-GREASFLPVLEGEQ 509
Y+GY + V LH +++ + GAPR++H GAVF L +E G + VLEG Q
Sbjct: 244 DQGNLYIGYTMQVGSFILHPK-NITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQ 302
Query: 510 MGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEE--GRVYVYRLSEQDGSFSLARILS 567
+G+YFGS + D++ DG D LLV AP+Y EE G +YV+ +++ SF L
Sbjct: 303 VGAYFGSAIALADLNNDGWQD-LLVGAPYYFERKEEVGGAIYVF-MNQAGTSFPAHPSLL 360
Query: 568 GHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSA 627
H G + + FG ++A++GD++QD D+A+GAP EG G VYIY+ GL
Sbjct: 361 LH-GPSGSAFGLSVASIGDINQDGFQDIAVGAPFEG--------LGKVYIYHSSSKGLLR 411
Query: 628 SPSQRIRASTVA-PGLQYFGMSMAGGFDISGDGLADITVGTLGQAVV-FRSRPVVRL-KV 684
P Q I + PGL FG S++G D+ + D+ VG+L +V R+RPV+ +
Sbjct: 412 QPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHK 471
Query: 685 SMAFTPSALPIGF---NGVVNVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRRLQ 741
++ P+ L V V LCF + + + + R L +TL+ D ++ RL+
Sbjct: 472 TLVPRPAVLDPALCTATSCVQVELCFAYNQ-SAGNPNYRRNITLAYTLEADRDRRPPRLR 530
Query: 742 CSDVRSCLGCLREWSSGSQLCEDLLLMPTEGELCEEDCFSNASVKVSYQLQTPEGQTDHP 801
+ S + +S C+ L L+ + D + ++Y L P D P
Sbjct: 531 FAGSESAV-FHGFFSMPEMRCQKLELLLMDN---LRDKLRPIIISMNYSL--PLRMPDRP 584
Query: 802 Q---------PILDRYTEPFAIFQLPYEKACKNKLFCVAELQL-ATTVSQQELVVGL--- 848
+ PIL++ ++ ++K C C + LQ+ A VS+Q+ +
Sbjct: 585 RLGLRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQY 644
Query: 849 ---TKELTLNINLTN------SGEDSYMTSMALNYPRNLQLKRMQKPPSPNIQCDDPQPV 899
++L L+IN+TN SGED++ + L P L L ++ P + C + +
Sbjct: 645 SRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPPGA----CQANETI 700
Query: 900 ASVLIMNCRIGHPVLKRSSAHVSVVWQLEENAFPNRTADITVTVTNSNERRSL 952
C +G+P + + + +++ R + + ++ S+ + +L
Sbjct: 701 F------CELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQDNL 747
Score = 42.7 bits (99), Expect = 0.002
Identities = 36/116 (31%), Positives = 61/116 (52%), Gaps = 9/116 (7%)
Query: 1065 NVTVAAEISWDHSEELLKDVTELQILGEIS-FNKSLYEGLNAENHRTKITVVFLKDEKYH 1123
NVTV A + E +D +++ G + F ++ +N EN T +V + E
Sbjct: 926 NVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVD-IDSELVE 984
Query: 1124 SLP------IIIKGSVGGLLVLIVILVILFKCGFFKRKYQQLNLESIR-KAQLKSE 1172
LP +++ GLL+L +I+++L+KCGFFKR + E+ R KA++KS+
Sbjct: 985 ELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRARTRALYEAKRQKAEMKSQ 1040
>gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]
Length = 1066
Score = 170 bits (431), Expect = 6e-42
Identities = 162/593 (27%), Positives = 276/593 (46%), Gaps = 70/593 (11%)
Query: 395 DALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAE 454
D L + Q+G S + V GA GA++W G + + + + + + D E
Sbjct: 190 DYLETGMCQLGTSGGFT-QNTVYFGAPGAYNWKGNSYMIQRKE-----WDLSEYSYKDPE 243
Query: 455 AAQYSYLGYAVAV----LHKTCSLSYIAGAPRYKHHGAVFELQKE-GREASFLPVLEGEQ 509
Y+GY + V LH +++ + GAPR++H GAVF L +E G + VLEG Q
Sbjct: 244 DQGNLYIGYTMQVGSFILHPK-NITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQ 302
Query: 510 MGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEE--GRVYVYRLSEQDGSFSLARILS 567
+G+YFGS + D++ DG D LLV AP+Y EE G +YV+ +++ SF L
Sbjct: 303 VGAYFGSAIALADLNNDGWQD-LLVGAPYYFERKEEVGGAIYVF-MNQAGTSFPAHPSLL 360
Query: 568 GHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSA 627
H G + + FG ++A++GD++QD D+A+GAP EG G VYIY+ GL
Sbjct: 361 LH-GPSGSAFGLSVASIGDINQDGFQDIAVGAPFEG--------LGKVYIYHSSSKGLLR 411
Query: 628 SPSQRIRASTVA-PGLQYFGMSMAGGFDISGDGLADITVGTLGQAVV-FRSRPVVRL-KV 684
P Q I + PGL FG S++G D+ + D+ VG+L +V R+RPV+ +
Sbjct: 412 QPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHK 471
Query: 685 SMAFTPSALPIGF---NGVVNVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRRLQ 741
++ P+ L V V LCF + + + + R L +TL+ D ++ RL+
Sbjct: 472 TLVPRPAVLDPALCTATSCVQVELCFAYNQ-SAGNPNYRRNITLAYTLEADRDRRPPRLR 530
Query: 742 CSDVRSCLGCLREWSSGSQLCEDLLLMPTEGELCEEDCFSNASVKVSYQLQTPEGQTDHP 801
+ S + +S C+ L L+ + D + ++Y L P D P
Sbjct: 531 FAGSESAV-FHGFFSMPEMRCQKLELLLMDN---LRDKLRPIIISMNYSL--PLRMPDRP 584
Query: 802 Q---------PILDRYTEPFAIFQLPYEKACKNKLFCVAELQL-ATTVSQQELVVGL--- 848
+ PIL++ ++ ++K C C + LQ+ A VS+Q+ +
Sbjct: 585 RLGLRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQY 644
Query: 849 ---TKELTLNINLTN------SGEDSYMTSMALNYPRNLQLKRMQKPPSPNIQCDDPQPV 899
++L L+IN+TN SGED++ + L P L L ++ P + C + +
Sbjct: 645 SRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPPGA----CQANETI 700
Query: 900 ASVLIMNCRIGHPVLKRSSAHVSVVWQLEENAFPNRTADITVTVTNSNERRSL 952
C +G+P + + + +++ R + + ++ S+ + +L
Sbjct: 701 F------CELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQDNL 747
Score = 36.6 bits (83), Expect = 0.14
Identities = 31/103 (30%), Positives = 53/103 (51%), Gaps = 9/103 (8%)
Query: 1065 NVTVAAEISWDHSEELLKDVTELQILGEIS-FNKSLYEGLNAENHRTKITVVFLKDEKYH 1123
NVTV A + E +D +++ G + F ++ +N EN T +V + E
Sbjct: 926 NVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVD-IDSELVE 984
Query: 1124 SLP------IIIKGSVGGLLVLIVILVILFKCGFFKR-KYQQL 1159
LP +++ GLL+L +I+++L+KC FFKR +Y Q+
Sbjct: 985 ELPAEIELWLVLVAVGAGLLLLGLIILLLWKCDFFKRTRYYQI 1027
>gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]
Length = 1002
Score = 159 bits (402), Expect = 1e-38
Identities = 148/517 (28%), Positives = 226/517 (43%), Gaps = 52/517 (10%)
Query: 395 DALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALL---------YDTRSRRGRFLNQ 445
DA Q GFS +VLLG G+F W G + YD ++ NQ
Sbjct: 132 DADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQ 191
Query: 446 TAAAAADAEAAQYSYLGYAVAV--LHKTCSLSYIAGAPRYKHHGAVFELQKEGREASFLP 503
A A A SYLGY+VAV + +++G PR + + +G+ S L
Sbjct: 192 LATRTAQA-IFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIY-DGKNMSSLY 249
Query: 504 VLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEGRVYVY-----RLSEQDG 558
GEQM +YFG + DI+ D D + + AP + G +G++ L G
Sbjct: 250 NFTGEQMAAYFGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVSLQRASG 308
Query: 559 SFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIY 618
F + L+G F ARFG A+A +GDL QD D+AI AP +G +D G VYI+
Sbjct: 309 DFQTTK-LNGFEVF--ARFGSAIAPLGDLDQDGFNDIAIAAP---YGGED--KKGIVYIF 360
Query: 619 NGHWDGLSASPSQRIRASTVAPGL-QYFGMSMAGGFDISGDGLADITVGTLG--QAVVFR 675
NG GL+A PSQ + A + FG SM G DI +G D+ VG G +A+++R
Sbjct: 361 NGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYR 420
Query: 676 SRPVVRLKVSMAFTPSAL-----PIGFNGVVNVRLCFEISSVTTASESGLREALLNFTLD 730
+RPV+ + + PS L G CF + A G+ LNF ++
Sbjct: 421 ARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVE 480
Query: 731 VDVGKQRRRLQCSDVRSCLGCLREWSS----------GSQLCEDLL-LMPTEGELCEEDC 779
+ + K +++ +R L S G CE+L+ + E E D
Sbjct: 481 LLLDKLKQK---GAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEF--RDK 535
Query: 780 FSNASVKVSYQLQ-TPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLATT 838
+ ++ + Y+L T QPIL+++T Q C C +L+++
Sbjct: 536 LTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD 595
Query: 839 VSQQELVVGLTKELTLNINLTNSGEDSYMTSMALNYP 875
Q+++ +G LTL + N GE +Y + ++ P
Sbjct: 596 SDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIP 632
Score = 31.2 bits (69), Expect = 6.1
Identities = 12/28 (42%), Positives = 21/28 (75%)
Query: 1127 IIIKGSVGGLLVLIVILVILFKCGFFKR 1154
+II + GLL+L V++ ++++ GFFKR
Sbjct: 950 VIILAVLAGLLLLAVLVFVMYRMGFFKR 977
>gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]
Length = 1048
Score = 159 bits (402), Expect = 1e-38
Identities = 148/517 (28%), Positives = 226/517 (43%), Gaps = 52/517 (10%)
Query: 395 DALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALL---------YDTRSRRGRFLNQ 445
DA Q GFS +VLLG G+F W G + YD ++ NQ
Sbjct: 178 DADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVYSIKYNNQ 237
Query: 446 TAAAAADAEAAQYSYLGYAVAV--LHKTCSLSYIAGAPRYKHHGAVFELQKEGREASFLP 503
A A A SYLGY+VAV + +++G PR + + +G+ S L
Sbjct: 238 LATRTAQA-IFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIY-DGKNMSSLY 295
Query: 504 VLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEGRVYVY-----RLSEQDG 558
GEQM +YFG + DI+ D D + + AP + G +G++ L G
Sbjct: 296 NFTGEQMAAYFGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQEVGQVSVSLQRASG 354
Query: 559 SFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIY 618
F + L+G F ARFG A+A +GDL QD D+AI AP +G +D G VYI+
Sbjct: 355 DFQTTK-LNGFEVF--ARFGSAIAPLGDLDQDGFNDIAIAAP---YGGED--KKGIVYIF 406
Query: 619 NGHWDGLSASPSQRIRASTVAPGL-QYFGMSMAGGFDISGDGLADITVGTLG--QAVVFR 675
NG GL+A PSQ + A + FG SM G DI +G D+ VG G +A+++R
Sbjct: 407 NGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYR 466
Query: 676 SRPVVRLKVSMAFTPSAL-----PIGFNGVVNVRLCFEISSVTTASESGLREALLNFTLD 730
+RPV+ + + PS L G CF + A G+ LNF ++
Sbjct: 467 ARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVE 526
Query: 731 VDVGKQRRRLQCSDVRSCLGCLREWSS----------GSQLCEDLL-LMPTEGELCEEDC 779
+ + K +++ +R L S G CE+L+ + E E D
Sbjct: 527 LLLDKLKQK---GAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEF--RDK 581
Query: 780 FSNASVKVSYQLQ-TPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLATT 838
+ ++ + Y+L T QPIL+++T Q C C +L+++
Sbjct: 582 LTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVD 641
Query: 839 VSQQELVVGLTKELTLNINLTNSGEDSYMTSMALNYP 875
Q+++ +G LTL + N GE +Y + ++ P
Sbjct: 642 SDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIP 678
Score = 31.2 bits (69), Expect = 6.1
Identities = 12/28 (42%), Positives = 21/28 (75%)
Query: 1127 IIIKGSVGGLLVLIVILVILFKCGFFKR 1154
+II + GLL+L V++ ++++ GFFKR
Sbjct: 996 VIILAVLAGLLLLAVLVFVMYRMGFFKR 1023
>gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]
Length = 1137
Score = 150 bits (378), Expect = 9e-36
Identities = 137/463 (29%), Positives = 216/463 (46%), Gaps = 60/463 (12%)
Query: 412 DERQVLLGAVGAFDWSGGALLYDTRSRRGRFLNQTAAAAAD------AEAAQYSYLGYAV 465
D +L GA G ++W G + + S L AD + A SYLG+++
Sbjct: 208 DSHYLLFGAPGTYNWKGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSI 267
Query: 466 AV---LHKTCSLSYIAGAPRYKHHGAVFELQKEGREASFLPV-LEGEQMGSYFGSELCPV 521
L + LS++AGAPR H GAV L+K+ V L GE++ S FG L
Sbjct: 268 DSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVA 327
Query: 522 DIDMDGSTDFLLVAAPFYHVHGEE--GRVYVYRLSEQDGSFSLARILSGHPGFTNARFGF 579
D++ DG D L+V AP++ EE G VYVY + L G P ++ FG
Sbjct: 328 DLNSDGWPD-LIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSP---DSMFGI 383
Query: 580 AMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSASPSQRIRASTVA 639
++A +GDL+QD D+A+GAP +G G V+IY+G G+ A PSQ + V
Sbjct: 384 SLAVLGDLNQDGFPDIAVGAPFDG--------DGKVFIYHGSSLGVVAKPSQVLEGEAV- 434
Query: 640 PGLQYFGMSMAGGFDISGDGLADITVGTLGQ-AVVFRSRPVVRLKVSMAFTPSALPI--- 695
G++ FG S++G D+ G+ D+ VG+L AV+FR+RP++ + ++ P ++ +
Sbjct: 435 -GIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQP 493
Query: 696 ----GFNGVVNVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRRLQCSDVRSCLGC 751
G + V++R+CF +V ++ L++ LD D + R R Q V
Sbjct: 494 NCAGGHSVCVDLRVCFSYIAVPSSYSP---TVALDYVLDADTDR-RLRGQVPRVTFLSRN 549
Query: 752 LRE---WSSGS--------QLCEDLLLMPTEGELCEEDCFSNASVKVSYQLQTPEGQTDH 800
L E +SG+ ++C D + E +D V +SY LQTP +
Sbjct: 550 LEEPKHQASGTVWLKHQHDRVCGDAMFQLQEN---VKDKLRAIVVTLSYSLQTPRLRRQA 606
Query: 801 P-------QPILDRYTEPFAIFQLPY-EKACKNKLFCVAELQL 835
P PIL+ + ++ + ++ C C + LQL
Sbjct: 607 PGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQL 649
Score = 33.5 bits (75), Expect = 1.2
Identities = 30/92 (32%), Positives = 43/92 (46%), Gaps = 11/92 (11%)
Query: 2 WLFHTLLCIASLALLAAFNVDVARPWLTPKG--GAPFVLSSLLHQDPSTN-QTWLLVTSP 58
+LF +LL + AFN+DV L +G G+ F S LH+ Q+WLLV +P
Sbjct: 17 YLFGSLLVELLFSRAVAFNLDVMGA-LRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAP 75
Query: 59 RTKRTPGP-------LHRCSLVQDEILCHPVE 83
+ PG L C L +E C+ V+
Sbjct: 76 QALALPGQQANRTGGLFACPLSLEETDCYRVD 107
Score = 32.0 bits (71), Expect = 3.6
Identities = 13/28 (46%), Positives = 22/28 (78%)
Query: 1127 IIIKGSVGGLLVLIVILVILFKCGFFKR 1154
+I+ + GLLVL +++++L+K GFFKR
Sbjct: 1040 VILLAVLAGLLVLALLVLLLWKMGFFKR 1067
>gi|119395740 integrin alpha chain, alpha 6 isoform a precursor
[Homo sapiens]
Length = 1091
Score = 148 bits (374), Expect = 3e-35
Identities = 147/617 (23%), Positives = 273/617 (44%), Gaps = 107/617 (17%)
Query: 412 DERQVLLGAVGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAEAA-------------QY 458
D ++ GA G ++W G + + F + E
Sbjct: 199 DFHYIVFGAPGTYNWKG---IVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPAN 255
Query: 459 SYLGYAV----AVLHKTCSLSYIAGAPRYKHHGAVFELQKEGREASFLP--VLEGEQMGS 512
SYLG+++ ++ K +++++GAPR H GAV L+++ + A LP + +GE + S
Sbjct: 256 SYLGFSLDSGKGIVSKD-EITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLAS 314
Query: 513 YFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEG-RVYVYRLSEQDGSFSLARILSGHPG 571
FG ++ VD++ DG D ++ A ++ GE G VYVY Q G ++ + + + G
Sbjct: 315 SFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYM--NQQGRWNNVKPIRLN-G 371
Query: 572 FTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSASPSQ 631
++ FG A+ +GD++QD D+A+GAP + G V+IY+G +G++ P+Q
Sbjct: 372 TKDSMFGIAVKNIGDINQDGYPDIAVGAPYD--------DLGKVFIYHGSANGINTKPTQ 423
Query: 632 RIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLGQAV-VFRSRPVVRLKVSMAFTP 690
++ ++P YFG S+AG D+ + D+ VG+L +V +FRSRPV+ ++ ++ TP
Sbjct: 424 VLKG--ISP---YFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTP 478
Query: 691 SALPI-------GFNGV-VNVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRRLQC 742
+ + + +G+ + V+ CFE TA+ +G + ++ ++ K+RR+
Sbjct: 479 NRIDLRQKTACGAPSGICLQVKSCFEY----TANPAGYNPS-ISIVGTLEAEKERRKSGL 533
Query: 743 SDVRSCLGCLREWSSGSQLCEDLLLMPTEGELCEE----------DCFSNASVKVSYQLQ 792
S R S + ++L L + ++C E D + S ++Q
Sbjct: 534 SSRVQ----FRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQ 589
Query: 793 TPEGQ---TDHPQ--PILDRYTEPFAIFQLPY-------EKACKNKL-----FCVAE--- 832
P + P+ PIL+ A + + + C + L FC E
Sbjct: 590 EPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQ 649
Query: 833 ---LQLATTVSQQELVVGLTKELTLNINLTNS----------GEDSYMTSMALNYPRNL- 878
L ELV+ K++ L I +TNS G+D++ + +P L
Sbjct: 650 DKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLT 709
Query: 879 --QLKRMQKPPSPNIQCDDPQPVASVLIMNCRIGHPVLKRSSAHVSVVWQLEENAFPNRT 936
+ ++ P + C Q + +C +G+P + S+ +V E F
Sbjct: 710 YSAYRELRAFPEKQLSCVANQNGSQA---DCELGNPFKRNSNVTFYLVLSTTEVTFDTPD 766
Query: 937 ADITVTVTNSNERRSLA 953
DI + + ++ + +LA
Sbjct: 767 LDINLKLETTSNQDNLA 783
Score = 37.0 bits (84), Expect = 0.11
Identities = 21/77 (27%), Positives = 40/77 (51%), Gaps = 5/77 (6%)
Query: 1101 EGLNAENHRTKITVVFLKDE---KYHSLP--IIIKGSVGGLLVLIVILVILFKCGFFKRK 1155
E + N T++ V + +Y +P II+ + G+L+L +++ IL+KCGFFKR
Sbjct: 986 ENIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRS 1045
Query: 1156 YQQLNLESIRKAQLKSE 1172
++ +++ E
Sbjct: 1046 RYDDSVPRYHAVRIRKE 1062
>gi|119395742 integrin alpha chain, alpha 6 isoform b precursor
[Homo sapiens]
Length = 1073
Score = 148 bits (374), Expect = 3e-35
Identities = 147/617 (23%), Positives = 273/617 (44%), Gaps = 107/617 (17%)
Query: 412 DERQVLLGAVGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAEAA-------------QY 458
D ++ GA G ++W G + + F + E
Sbjct: 199 DFHYIVFGAPGTYNWKG---IVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESLVPVPAN 255
Query: 459 SYLGYAV----AVLHKTCSLSYIAGAPRYKHHGAVFELQKEGREASFLP--VLEGEQMGS 512
SYLG+++ ++ K +++++GAPR H GAV L+++ + A LP + +GE + S
Sbjct: 256 SYLGFSLDSGKGIVSKD-EITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDGEGLAS 314
Query: 513 YFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEG-RVYVYRLSEQDGSFSLARILSGHPG 571
FG ++ VD++ DG D ++ A ++ GE G VYVY Q G ++ + + + G
Sbjct: 315 SFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYM--NQQGRWNNVKPIRLN-G 371
Query: 572 FTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSASPSQ 631
++ FG A+ +GD++QD D+A+GAP + G V+IY+G +G++ P+Q
Sbjct: 372 TKDSMFGIAVKNIGDINQDGYPDIAVGAPYD--------DLGKVFIYHGSANGINTKPTQ 423
Query: 632 RIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLGQAV-VFRSRPVVRLKVSMAFTP 690
++ ++P YFG S+AG D+ + D+ VG+L +V +FRSRPV+ ++ ++ TP
Sbjct: 424 VLKG--ISP---YFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTP 478
Query: 691 SALPI-------GFNGV-VNVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRRLQC 742
+ + + +G+ + V+ CFE TA+ +G + ++ ++ K+RR+
Sbjct: 479 NRIDLRQKTACGAPSGICLQVKSCFEY----TANPAGYNPS-ISIVGTLEAEKERRKSGL 533
Query: 743 SDVRSCLGCLREWSSGSQLCEDLLLMPTEGELCEE----------DCFSNASVKVSYQLQ 792
S R S + ++L L + ++C E D + S ++Q
Sbjct: 534 SSRVQ----FRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQ 589
Query: 793 TPEGQ---TDHPQ--PILDRYTEPFAIFQLPY-------EKACKNKL-----FCVAE--- 832
P + P+ PIL+ A + + + C + L FC E
Sbjct: 590 EPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKLEYKFCTREGNQ 649
Query: 833 ---LQLATTVSQQELVVGLTKELTLNINLTNS----------GEDSYMTSMALNYPRNL- 878
L ELV+ K++ L I +TNS G+D++ + +P L
Sbjct: 650 DKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLT 709
Query: 879 --QLKRMQKPPSPNIQCDDPQPVASVLIMNCRIGHPVLKRSSAHVSVVWQLEENAFPNRT 936
+ ++ P + C Q + +C +G+P + S+ +V E F
Sbjct: 710 YSAYRELRAFPEKQLSCVANQNGSQA---DCELGNPFKRNSNVTFYLVLSTTEVTFDTPD 766
Query: 937 ADITVTVTNSNERRSLA 953
DI + + ++ + +LA
Sbjct: 767 LDINLKLETTSNQDNLA 783
Score = 38.1 bits (87), Expect = 0.050
Identities = 22/77 (28%), Positives = 42/77 (54%), Gaps = 5/77 (6%)
Query: 1101 EGLNAENHRTKITVVFLKDE---KYHSLP--IIIKGSVGGLLVLIVILVILFKCGFFKRK 1155
E + N T++ V + +Y +P II+ + G+L+L +++ IL+KCGFFKR
Sbjct: 986 ENIRLPNAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRN 1045
Query: 1156 YQQLNLESIRKAQLKSE 1172
+ + KA++ ++
Sbjct: 1046 KKDHYDATYHKAEIHAQ 1062
>gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]
Length = 1012
Score = 146 bits (369), Expect = 1e-34
Identities = 134/470 (28%), Positives = 209/470 (44%), Gaps = 43/470 (9%)
Query: 433 YDTRSRRGRFLNQTAAAAADAEAAQYSYLGYAVAV--LHKTCSLSYIAGAPRYKHHGAVF 490
YD ++ NQ A A A SYLGY+VAV + +++G PR +
Sbjct: 189 YDPNVYSIKYNNQLATRTAQA-IFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMV 247
Query: 491 ELQKEGREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEGRVYV 550
+ +G+ S L GEQM +YFG + DI+ D D + + AP + G +G++
Sbjct: 248 YIY-DGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYAD-VFIGAPLFMDRGSDGKLQE 305
Query: 551 Y-----RLSEQDGSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFG 605
L G F + L+G F ARFG A+A +GDL QD D+AI AP +G
Sbjct: 306 VGQVSVSLQRASGDFQTTK-LNGFEVF--ARFGSAIAPLGDLDQDGFNDIAIAAP---YG 359
Query: 606 ADDGASFGSVYIYNGHWDGLSASPSQRIRASTVAPGL-QYFGMSMAGGFDISGDGLADIT 664
+D G VYI+NG GL+A PSQ + A + FG SM G DI +G D+
Sbjct: 360 GED--KKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLI 417
Query: 665 VGTLG--QAVVFRSRPVVRLKVSMAFTPSAL-----PIGFNGVVNVRLCFEISSVTTASE 717
VG G +A+++R+RPV+ + + PS L G CF + A
Sbjct: 418 VGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADG 477
Query: 718 SGLREALLNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSS----------GSQLCEDLL- 766
G+ LNF +++ + K +++ +R L S G CE+L+
Sbjct: 478 KGVLPRKLNFQVELLLDKLKQK---GAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIA 534
Query: 767 LMPTEGELCEEDCFSNASVKVSYQLQ-TPEGQTDHPQPILDRYTEPFAIFQLPYEKACKN 825
+ E E D + ++ + Y+L T QPIL+++T Q C
Sbjct: 535 YLRDESEF--RDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGE 592
Query: 826 KLFCVAELQLATTVSQQELVVGLTKELTLNINLTNSGEDSYMTSMALNYP 875
C +L+++ Q+++ +G LTL + N GE +Y + ++ P
Sbjct: 593 DNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIP 642
Score = 31.2 bits (69), Expect = 6.1
Identities = 12/28 (42%), Positives = 21/28 (75%)
Query: 1127 IIIKGSVGGLLVLIVILVILFKCGFFKR 1154
+II + GLL+L V++ ++++ GFFKR
Sbjct: 960 VIILAVLAGLLLLAVLVFVMYRMGFFKR 987
>gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]
Length = 1044
Score = 145 bits (365), Expect = 3e-34
Identities = 137/475 (28%), Positives = 215/475 (45%), Gaps = 80/475 (16%)
Query: 412 DERQVLLGAVGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAEAAQY------------- 458
D +L GA G ++W G A R Q +A A + Y
Sbjct: 111 DSHYLLFGAPGTYNWKGTA--------RVELCAQGSADLAHLDDGPYEAGGEKEQDPRLI 162
Query: 459 -----SYLGYAVAV---LHKTCSLSYIAGAPRYKHHGAVFELQKEGREASFLPV-LEGEQ 509
SY G+++ L + LS++AGAPR H GAV L+K+ V L GE+
Sbjct: 163 PVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGER 222
Query: 510 MGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEE--GRVYVYRLSEQDGSFSLARILS 567
+ S FG L D++ DG D L+V AP++ EE G VYVY + L
Sbjct: 223 LTSGFGYSLAVADLNSDGWPD-LIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLC 281
Query: 568 GHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSA 627
G P ++ FG ++A +GDL+QD D+A+GAP +G G V+IY+G G+ A
Sbjct: 282 GSP---DSMFGISLAVLGDLNQDGFPDIAVGAPFDG--------DGKVFIYHGSSLGVVA 330
Query: 628 SPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLGQ-AVVFRSRPVVRLKVSM 686
PSQ + V G++ FG S++G D+ G+ D+ VG+L AV+FR+RP++ + +
Sbjct: 331 KPSQVLEGEAV--GIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEV 388
Query: 687 AFTPSALPI-------GFNGVVNVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRR 739
+ P ++ + G + V++R+CF +V ++ L++ LD D + R R
Sbjct: 389 SIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSP---TVALDYVLDADTDR-RLR 444
Query: 740 LQCSDVRSCLGCLRE---WSSGS--------QLCEDLLLMPTEGELCEEDCFSNASVKVS 788
Q V L E +SG+ ++C D + E +D V +S
Sbjct: 445 GQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQEN---VKDKLRAIVVTLS 501
Query: 789 YQLQTPEGQTDHP-------QPILDRYTEPFAIFQLPY-EKACKNKLFCVAELQL 835
Y LQTP + P PIL+ + ++ + ++ C C + LQL
Sbjct: 502 YSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQL 556
Score = 32.0 bits (71), Expect = 3.6
Identities = 13/28 (46%), Positives = 22/28 (78%)
Query: 1127 IIIKGSVGGLLVLIVILVILFKCGFFKR 1154
+I+ + GLLVL +++++L+K GFFKR
Sbjct: 947 VILLAVLAGLLVLALLVLLLWKMGFFKR 974
>gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]
Length = 1141
Score = 145 bits (365), Expect = 3e-34
Identities = 137/475 (28%), Positives = 215/475 (45%), Gaps = 80/475 (16%)
Query: 412 DERQVLLGAVGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAEAAQY------------- 458
D +L GA G ++W G A R Q +A A + Y
Sbjct: 208 DSHYLLFGAPGTYNWKGTA--------RVELCAQGSADLAHLDDGPYEAGGEKEQDPRLI 259
Query: 459 -----SYLGYAVAV---LHKTCSLSYIAGAPRYKHHGAVFELQKEGREASFLPV-LEGEQ 509
SY G+++ L + LS++AGAPR H GAV L+K+ V L GE+
Sbjct: 260 PVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGER 319
Query: 510 MGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEE--GRVYVYRLSEQDGSFSLARILS 567
+ S FG L D++ DG D L+V AP++ EE G VYVY + L
Sbjct: 320 LTSGFGYSLAVADLNSDGWPD-LIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLC 378
Query: 568 GHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSA 627
G P ++ FG ++A +GDL+QD D+A+GAP +G G V+IY+G G+ A
Sbjct: 379 GSP---DSMFGISLAVLGDLNQDGFPDIAVGAPFDG--------DGKVFIYHGSSLGVVA 427
Query: 628 SPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLGQ-AVVFRSRPVVRLKVSM 686
PSQ + V G++ FG S++G D+ G+ D+ VG+L AV+FR+RP++ + +
Sbjct: 428 KPSQVLEGEAV--GIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEV 485
Query: 687 AFTPSALPI-------GFNGVVNVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRR 739
+ P ++ + G + V++R+CF +V ++ L++ LD D + R R
Sbjct: 486 SIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSP---TVALDYVLDADTDR-RLR 541
Query: 740 LQCSDVRSCLGCLRE---WSSGS--------QLCEDLLLMPTEGELCEEDCFSNASVKVS 788
Q V L E +SG+ ++C D + E +D V +S
Sbjct: 542 GQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQEN---VKDKLRAIVVTLS 598
Query: 789 YQLQTPEGQTDHP-------QPILDRYTEPFAIFQLPY-EKACKNKLFCVAELQL 835
Y LQTP + P PIL+ + ++ + ++ C C + LQL
Sbjct: 599 YSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQL 653
Score = 33.5 bits (75), Expect = 1.2
Identities = 30/92 (32%), Positives = 43/92 (46%), Gaps = 11/92 (11%)
Query: 2 WLFHTLLCIASLALLAAFNVDVARPWLTPKG--GAPFVLSSLLHQDPSTN-QTWLLVTSP 58
+LF +LL + AFN+DV L +G G+ F S LH+ Q+WLLV +P
Sbjct: 17 YLFGSLLVELLFSRAVAFNLDVMGA-LRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAP 75
Query: 59 RTKRTPGP-------LHRCSLVQDEILCHPVE 83
+ PG L C L +E C+ V+
Sbjct: 76 QALALPGQQANRTGGLFACPLSLEETDCYRVD 107
Score = 32.0 bits (71), Expect = 3.6
Identities = 13/28 (46%), Positives = 22/28 (78%)
Query: 1127 IIIKGSVGGLLVLIVILVILFKCGFFKR 1154
+I+ + GLLVL +++++L+K GFFKR
Sbjct: 1044 VILLAVLAGLLVLALLVLLLWKMGFFKR 1071
>gi|56237029 integrin alpha 5 precursor [Homo sapiens]
Length = 1049
Score = 144 bits (364), Expect = 4e-34
Identities = 216/873 (24%), Positives = 353/873 (40%), Gaps = 141/873 (16%)
Query: 403 QIGFSAQILDERQVLLGAVGAFDWSGGALL-------------YDTRSRRGRFLNQTAAA 449
Q GFSA+ +V+LG G++ W G L Y +G+ + A++
Sbjct: 206 QGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQIAESYYPEYLINLVQGQLQTRQASS 265
Query: 450 AADAEAAQYSYLGYAVAV--LHKTCSLSYIAGAPRYK-HHGAVFELQKEGREASFLPVLE 506
D SYLGY+VAV + ++AG P+ +G V L G + L
Sbjct: 266 IYDD-----SYLGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYVTILN--GSDIRSLYNFS 318
Query: 507 GEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHG------EEGRVYVYRLSEQDGSF 560
GEQM SYFG + D++ DG D LLV AP E GRVYVY
Sbjct: 319 GEQMASYFGYAVAATDVNGDGLDD-LLVGAPLLMDRTPDGRPQEVGRVYVYLQHPAGIEP 377
Query: 561 SLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIYNG 620
+ L+GH F RFG ++ +GDL QD DVAIGAP FG + G V+++ G
Sbjct: 378 TPTLTLTGHDEF--GRFGSSLTPLGDLDQDGYNDVAIGAP---FGGE--TQQGVVFVFPG 430
Query: 621 HWDGLSASPSQRIR---ASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLG--QAVVFR 675
GL + PSQ ++ A++ P +FG ++ GG D+ G+G D+ VG+ G +AVV+R
Sbjct: 431 GPGGLGSKPSQVLQPLWAASHTP--DFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYR 488
Query: 676 SRPVVRLKVSMA-----FTPSALPIGFNGVVNVRLCFEISSVTTASESGLREALLNFTLD 730
RP+V S+ F P G N C +S AS + ++ + FT++
Sbjct: 489 GRPIVSASASLTIFPAMFNPEERSCSLEG--NPVACINLSFCLNASGKHVADS-IGFTVE 545
Query: 731 VDVGKQRRRLQCSDVRSCLGCLREWSSGSQLCEDLLLMPTEGELCEE------------D 778
+ + Q+++ VR L S + L + LL+ E C E D
Sbjct: 546 LQLDWQKQK---GGVRRALFLA---SRQATLTQTLLIQNGAREDCREMKIYLRNESEFRD 599
Query: 779 CFSNASVKVSYQLQTPEGQTDHP--QPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLA 836
S + +++ L P+ D +P L ++ + C CV +LQL
Sbjct: 600 KLSPIHIALNFSLD-PQAPVDSHGLRPALHYQSKSRIEDKAQILLDCGEDNICVPDLQLE 658
Query: 837 TTVSQQELVVGLTKELTLNINLTNSGE-DSYMTSMALNYPRNLQLKRMQKPPS--PNIQC 893
Q + +G L L + N GE +Y + + P + + + P ++ C
Sbjct: 659 VFGEQNHVYLGDKNALNLTFHAQNVGEGGAYEAELRVTAPPEAEYSGLVRHPGNFSSLSC 718
Query: 894 DDPQPVASVLIMNCRIGHPVLKRSSAHVSVVWQLEENAFPNRTADITVTVTNSNERRSLA 953
D S L++ C +G+P+ +S + + + +T + + N S
Sbjct: 719 DYFAVNQSRLLV-CDLGNPMKAGASLWGGLRFTVPHLRDTKKTIQFDFQILSKNLNNS-- 775
Query: 954 NETHTLQFRHGFVAV-------LSKPSIMYV---------------NTGQGLSHHKEFLF 991
++ + FR A +SKP + + G + H E +
Sbjct: 776 -QSDVVSFRLSVEAQAQVTLNGVSKPEAVLFPVSDWHPRDQPQKEEDLGPAVHHVYELIN 834
Query: 992 HVHGENLFGAEYQLQICVPTKLRGLQVVAVKKLTRTQASTVCTWSQE--RACAYSSVQHV 1049
G L++ P L G Q++ V ++T +T + + S+ H
Sbjct: 835 QGPSSISQGV---LELSCPQALEGQQLLYVTRVTGLNCTTNHPINPKGLELDPEGSLHHQ 891
Query: 1050 EEWHSVSCVIAS---------DKENVTVAAEISWDHSEELLKDVTELQILGEISFNK--- 1097
++ + S AS + E + E+ H +E ++ + +
Sbjct: 892 QKREAPSRSSASSGPQILKCPEAECFRLRCELGPLHQQESQSLQLHFRVWAKTFLQREHQ 951
Query: 1098 -------SLYEGLN----------AENHRTKITVV-FLKDEKYHSLP--IIIKGSVGGLL 1137
++Y+ L + R T V + K E + +P III + GLL
Sbjct: 952 PFSLQCEAVYKALKMPYRILPRQLPQKERQVATAVQWTKAEGSYGVPLWIIILAILFGLL 1011
Query: 1138 VLIVILVILFKCGFFKRKYQQLNLESIRKAQLK 1170
+L +++ IL+K GFFKR ++ KAQLK
Sbjct: 1012 LLGLLIYILYKLGFFKRSLPYGT--AMEKAQLK 1042
>gi|49170034 integrin, alpha 8 [Homo sapiens]
Length = 1063
Score = 142 bits (357), Expect = 2e-33
Identities = 157/634 (24%), Positives = 268/634 (42%), Gaps = 73/634 (11%)
Query: 403 QIGFSAQILDERQVLLGAVGAFDWSGGALLYDT-------------RSRRGRFLNQTAAA 449
Q GFS +++G G+F W G + R G + A A
Sbjct: 201 QAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLAGEKQTEVAPA 260
Query: 450 AADAEAAQYSYLGYAVAVLHKT--CSLSYIAGAPRYKHHGAVFELQKEGREASFLPVLEG 507
+ D SYLGY+VA T +AG PR + + + +F+ G
Sbjct: 261 SYDD-----SYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSIINS-TDMTFIQNFTG 314
Query: 508 EQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHG------EEGRVYVYRLSEQDGSFS 561
EQM SYFG + D++ DG D +LV AP + E G++Y+Y L F
Sbjct: 315 EQMASYFGYTVVVSDVNSDGLDD-VLVGAPLFMEREFESNPREVGQIYLY-LQVSSLLFR 372
Query: 562 LARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIYNGH 621
+IL+G F RFG AMA +GDL+QD D+AIG P G G V IYNG+
Sbjct: 373 DPQILTGTETF--GRFGSAMAHLGDLNQDGYNDIAIGVPFAG-----KDQRGKVLIYNGN 425
Query: 622 WDGLSASPSQRIR---ASTVAPGLQYFGMSMAGGFDISGDGLADITVGTL--GQAVVFRS 676
DGL+ PSQ ++ AS P FG ++ G DI + D+ VG G+ V+R+
Sbjct: 426 KDGLNTKPSQVLQGVWASHAVP--SGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRA 483
Query: 677 RPVVRLKVSMAFTPSALPIGFNGVVNV------RLCFEIS-SVTTASESGLREALLNFTL 729
RPVV + + P + + N V CF + + +S +L +
Sbjct: 484 RPVVTVDAQLLLHPMIINLE-NKTCQVPDSMTSAACFSLRVCASVTGQSIANTIVLMAEV 542
Query: 730 DVDVGKQRRRLQCSDVRSCLGCLREW-----SSGSQLCEDLLLMPTEGELCEEDCFSNAS 784
+D KQ+ ++ + R + S C+D ++ E D S +
Sbjct: 543 QLDSLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVY-LRDETEFRDKLSPIN 601
Query: 785 VKVSYQL-QTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLATTVSQQE 843
+ ++Y L ++ + +PIL+ Y E Q C CV +L+L+ + +
Sbjct: 602 ISLNYSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNLCVPDLKLSARPDKHQ 661
Query: 844 LVVGLTKELTLNINLTNSGEDSYMTSMALNYPRN---LQLKRMQKPPSPNIQCDDPQPVA 900
+++G L L IN N GE +Y + + P + ++R K P + C+
Sbjct: 662 VIIGDENHLMLIINARNEGEGAYEAELFVMIPEEADYVGIERNNKGFRP-LSCEYKMENV 720
Query: 901 SVLIMNCRIGHPVLKRSSAHVSVVWQLEENAFPNRTADITVTVTNSNERRSLANETHTLQ 960
+ +++ C +G+P++ ++ + + + + N + + + + +SN+ +N
Sbjct: 721 TRMVV-CDLGNPMVSGTNYSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSN------ 773
Query: 961 FRHGFVAVLSKPSIMYVNTGQGLSHHKEFLFHVH 994
FV++ + + +G+SH + + +H
Sbjct: 774 ----FVSLQINITAVAQVEIRGVSHPPQIVLPIH 803
Score = 33.5 bits (75), Expect = 1.2
Identities = 18/46 (39%), Positives = 28/46 (60%), Gaps = 2/46 (4%)
Query: 1111 KITVVFLKDEKYHSLP--IIIKGSVGGLLVLIVILVILFKCGFFKR 1154
K +V++ S+P +II + GLLVL ++ + L+KCGFF R
Sbjct: 996 KTSVIWATPNVSFSIPLWVIILAILLGLLVLAILTLALWKCGFFDR 1041
>gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]
Length = 1039
Score = 130 bits (326), Expect = 1e-29
Identities = 155/577 (26%), Positives = 249/577 (43%), Gaps = 82/577 (14%)
Query: 403 QIGFSAQILDERQVLLGAVGAFDWSG----------------GALLYDTRSRRGRFLNQT 446
+ GFS+ + +++LGA G + + G G LL+ S+ F
Sbjct: 199 EAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSF---- 254
Query: 447 AAAAADAEAAQY--SYLGYAVAVLHKTCSLS---YIAGAPRYKHHGAVFELQKEGREASF 501
D+ +Y Y GY+VAV L+ Y+ GAP + E+ +
Sbjct: 255 -----DSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQR-- 307
Query: 502 LPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVH------GEEGRVYVY---R 552
L L GEQM SYFG + D++ DG D LLV AP Y E GRVY++ R
Sbjct: 308 LHRLRGEQMASYFGHSVAVTDVNGDGRHD-LLVGAPLYMESRADRKLAEVGRVYLFLQPR 366
Query: 553 LSEQDGSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASF 612
G+ SL +L+G + RFG A+A +GDL +D D+A+ AP +G G
Sbjct: 367 GPHALGAPSL--LLTGTQLY--GRFGSAIAPLGDLDRDGYNDIAVAAP---YGGPSGR-- 417
Query: 613 GSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLG--Q 670
G V ++ G +GL + PSQ + + P FG S+ G DI +G D+ VG G Q
Sbjct: 418 GQVLVFLGQSEGLRSRPSQVL--DSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQ 475
Query: 671 AVVFRSRPVVRLKVSMAFTPSALPIGFNGVV----NVRLCFEISSVTTASESGLREAL-L 725
V+R++PVV+ V + S P + V+ CF I A+ + + L L
Sbjct: 476 VAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSL 535
Query: 726 NFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQLCEDL------LLMPTEGELCEEDC 779
N L +D K R+ + + L +G+ L DL + T L +E
Sbjct: 536 NAELQLDRQKPRQGRR-------VLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEAD 588
Query: 780 FSN--ASVKVSYQLQTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLAT 837
F + + + +S + P + P + + + Q C CV +LQL
Sbjct: 589 FRDKLSPIVLSLNVSLPPTEAG-MAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTA 647
Query: 838 TVSQQELVVGLTKELTLNINLTNSGEDSYMTSMALNYPRNLQLKRMQKPPS--PNIQCDD 895
+V+ L+VG L L ++ N GE +Y +A++ P+ R + C+
Sbjct: 648 SVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQ 707
Query: 896 PQPVASVLIMNCRIGHPVLKRSSAHVSV---VWQLEE 929
+ + +++ C +G+P+ K + +++ V LEE
Sbjct: 708 KKENETRVVL-CELGNPMKKNAQIGIAMLVSVGNLEE 743
Score = 33.5 bits (75), Expect = 1.2
Identities = 16/54 (29%), Positives = 33/54 (61%), Gaps = 2/54 (3%)
Query: 1103 LNAENHRTKITVVFLKDEKYHSLPI--IIKGSVGGLLVLIVILVILFKCGFFKR 1154
L+ ++ L+ + ++PI ++ G +GGLL+L ++++ ++K GFFKR
Sbjct: 973 LSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKR 1026
>gi|93141049 collagen, type XII, alpha 1 short isoform precursor
[Homo sapiens]
Length = 1899
Score = 94.7 bits (234), Expect = 4e-19
Identities = 67/207 (32%), Positives = 104/207 (50%), Gaps = 8/207 (3%)
Query: 189 EEEEDEEEEEAGTEIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGG 248
E E E A +I +++DGS SI +F+ + FIS ++ F AL QY G
Sbjct: 22 EAEGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSG 81
Query: 249 VIQTEFDLRDSQDVMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSRRKASKVMV 308
+TE+ L +D + L V N+ G T T A+ + F + G R +A K+ V
Sbjct: 82 DPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGV 141
Query: 309 VLTDGGIFEDPLNLTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASDPDETHAFK 368
++TDG +D + K +GVE FAIG+ K+A EL +IA+DPD+THA+
Sbjct: 142 LITDGKSQDD---VEAPSKKLKDEGVELFAIGI----KNADEV-ELKMIATDPDDTHAYN 193
Query: 369 VTNYMALDGLLSKLRYNIISMEGTVGD 395
V ++ +L ++ L N+ + GD
Sbjct: 194 VADFESLSRIVDDLTINLCNSVKGPGD 220
Score = 75.1 bits (183), Expect = 4e-13
Identities = 56/191 (29%), Positives = 87/191 (45%), Gaps = 13/191 (6%)
Query: 199 AGTEIAIILDGSGSIDPPDFQRAKDFISNMMRNFYE-KCFECNFALVQYGGVIQTEFDLR 257
A +I + D S SI +F + FI N + F E + VQY +++EF L
Sbjct: 1156 AKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLN 1215
Query: 258 DSQDVMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFE 317
D +L +QNI G T+T A+ + + + T G R+ KV+VV+TDG +
Sbjct: 1216 TYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQD 1275
Query: 318 DPLNLTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASDPDETHAFKVTNYMALDG 377
+ VI + G F +GV + EL IAS P E H F V ++ + +
Sbjct: 1276 EVKKAALVI---QQSGFSVFVVGVADV-----DYNELANIASKPSERHVFIVDDFESFE- 1326
Query: 378 LLSKLRYNIIS 388
K+ N+I+
Sbjct: 1327 ---KIEDNLIT 1334
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
sapiens]
Length = 3063
Score = 94.4 bits (233), Expect = 6e-19
Identities = 64/197 (32%), Positives = 101/197 (51%), Gaps = 8/197 (4%)
Query: 199 AGTEIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRD 258
A +I +++DGS SI +F+ + FIS ++ F AL QY G +TE+ L
Sbjct: 1196 AEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNA 1255
Query: 259 SQDVMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFED 318
+D + L V N+ G T T A+ + F + G R +A K+ V++TDG +D
Sbjct: 1256 HRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDD 1315
Query: 319 PLNLTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASDPDETHAFKVTNYMALDGL 378
+ K +GVE FAIG+ K+A EL +IA+DPD+THA+ V ++ +L +
Sbjct: 1316 ---VEAPSKKLKDEGVELFAIGI----KNADEV-ELKMIATDPDDTHAYNVADFESLSRI 1367
Query: 379 LSKLRYNIISMEGTVGD 395
+ L N+ + GD
Sbjct: 1368 VDDLTINLCNSVKGPGD 1384
Score = 85.1 bits (209), Expect = 4e-16
Identities = 65/217 (29%), Positives = 103/217 (47%), Gaps = 14/217 (6%)
Query: 173 TARQRRALEKEEEEDKEEEEDEEEEEAGTEIAIILDGSGSIDPPDFQRAKDFISNMMRNF 232
T+ + ++ ++ + K + E + +I ++DGS SI +F + + F+ ++++F
Sbjct: 411 TSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSF 470
Query: 233 YEKCFECNFALVQYGGVIQTEFDLRDSQDVMASLARVQNITQVGSVTKTASAMQHVLDSI 292
+LVQY TEF L+ V + + G T T AM +V + I
Sbjct: 471 EISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKI 530
Query: 293 FTSSHGSRRKASKVMVVLTDG---GIFEDPLNLTTVINSPKMQGVERFAIGVGEEFKSAR 349
F S GSR KVM+++TDG F DP + NS VE FA+GV + +S
Sbjct: 531 FVPSKGSRSNVPKVMILITDGKSSDAFRDP--AIKLRNS----DVEIFAVGVKDAVRS-- 582
Query: 350 TARELNLIASDPDETHAFKVTNYMALDGLLSKLRYNI 386
EL IAS P ETH F V ++ A + +L +I
Sbjct: 583 ---ELEAIASPPAETHVFTVEDFDAFQRISFELTQSI 616
Score = 79.3 bits (194), Expect = 2e-14
Identities = 60/222 (27%), Positives = 107/222 (48%), Gaps = 11/222 (4%)
Query: 167 GEDDVNTARQRRALEKEEEEDKEEEEDEEEEEAGTEIAIILDGSGSIDPPDFQRAKDFIS 226
G+ + T + +EK+ + E + A T++ ++DGS S+ +F+ DFI+
Sbjct: 108 GQLTIQTGSSTKPVEKKPGKT---EIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIA 164
Query: 227 NMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQDVMASLARVQNITQVGSVTKTASAMQ 286
++ F + +VQY +TEF+L LA ++ I G T T A+
Sbjct: 165 ALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAID 224
Query: 287 HVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPLNLTTVINSPKMQGVERFAIGVGEEFK 346
+++ + FT S G+R KV +++TDG +D + + + GVE F++G+
Sbjct: 225 YLVKNTFTESAGARVGFPKVAIIITDGK-SQDEVEIPA--RELRNVGVEVFSLGI----- 276
Query: 347 SARTARELNLIASDPDETHAFKVTNYMALDGLLSKLRYNIIS 388
A A+EL IAS P H F V N+ A+ + +++ + S
Sbjct: 277 KAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCS 318
Score = 75.1 bits (183), Expect = 4e-13
Identities = 56/191 (29%), Positives = 87/191 (45%), Gaps = 13/191 (6%)
Query: 199 AGTEIAIILDGSGSIDPPDFQRAKDFISNMMRNFYE-KCFECNFALVQYGGVIQTEFDLR 257
A +I + D S SI +F + FI N + F E + VQY +++EF L
Sbjct: 2320 AKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLN 2379
Query: 258 DSQDVMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFE 317
D +L +QNI G T+T A+ + + + T G R+ KV+VV+TDG +
Sbjct: 2380 TYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQD 2439
Query: 318 DPLNLTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASDPDETHAFKVTNYMALDG 377
+ VI + G F +GV + EL IAS P E H F V ++ + +
Sbjct: 2440 EVKKAALVI---QQSGFSVFVVGVADV-----DYNELANIASKPSERHVFIVDDFESFE- 2490
Query: 378 LLSKLRYNIIS 388
K+ N+I+
Sbjct: 2491 ---KIEDNLIT 2498
>gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]
Length = 1284
Score = 84.7 bits (208), Expect = 5e-16
Identities = 64/184 (34%), Positives = 96/184 (52%), Gaps = 11/184 (5%)
Query: 202 EIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQD 261
++ ++DGS SI FQ+ KDF+++++ F + L QY G QTE+DL
Sbjct: 179 DMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSLST 238
Query: 262 VMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPLN 321
LA V+ + G T T A+ HVL + G R +A+KV++++TDG +D
Sbjct: 239 KEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGKSQDDVHT 298
Query: 322 LTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASDPDETHAFKVTNYM---ALDGL 378
V+ K GV FA+GV K+A A EL L+AS P + V +++ AL GL
Sbjct: 299 AARVL---KDLGVNVFAVGV----KNADEA-ELRLLASPPRDITVHSVLDFLQLGALAGL 350
Query: 379 LSKL 382
LS+L
Sbjct: 351 LSRL 354
>gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens]
Length = 496
Score = 83.2 bits (204), Expect = 1e-15
Identities = 57/188 (30%), Positives = 94/188 (50%), Gaps = 8/188 (4%)
Query: 199 AGTEIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRD 258
+ T++ ++DGS S+ P +F+ K FIS ++ LVQY ++ EF L
Sbjct: 272 SATDLVFLIDGSKSVRPENFELVKKFISQIVDTLDVSDKLAQVGLVQYSSSVRQEFPLGR 331
Query: 259 SQDVMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFED 318
A V+N++ + T T +A+++++D+ FT S G+R A KV +V TDG +D
Sbjct: 332 FHTKKDIKAAVRNMSYMEKGTMTGAALKYLIDNSFTVSSGARPGAQKVGIVFTDGR-SQD 390
Query: 319 PLNLTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASDPDETHAFKVTNYMALDGL 378
+N K G + FA+GVG + EL IAS+P H F ++ ++ +
Sbjct: 391 YIN--DAAKKAKDLGFKMFAVGVGNAVED-----ELREIASEPVAEHYFYTADFKTINQI 443
Query: 379 LSKLRYNI 386
KL+ I
Sbjct: 444 GKKLQKKI 451
Score = 79.3 bits (194), Expect = 2e-14
Identities = 54/186 (29%), Positives = 90/186 (48%), Gaps = 11/186 (5%)
Query: 201 TEIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQ 260
T++ ++D S S+ P +F++ K F+S ++ + +V Y ++ EF LR
Sbjct: 40 TDLVFVVDSSRSVRPVEFEKVKVFLSQVIESLDVGPNATRVGMVNYASTVKQEFSLRAHV 99
Query: 261 DVMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSRRKA---SKVMVVLTDGGIFE 317
A L V+ I + + T T A+Q + F + G R ++ SKV++V+TDG
Sbjct: 100 SKAALLQAVRRIQPLSTGTMTGLAIQFAITKAFGDAEGGRSRSPDISKVVIVVTDG---R 156
Query: 318 DPLNLTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASDPDETHAFKVTNYMALDG 377
++ V + GVE FAIGVG K+ L IAS+P + H V +Y ++
Sbjct: 157 PQDSVQDVSARARASGVELFAIGVGSVDKAT-----LRQIASEPQDEHVDYVESYSVIEK 211
Query: 378 LLSKLR 383
L K +
Sbjct: 212 LSRKFQ 217
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,605,817
Number of Sequences: 37866
Number of extensions: 2118866
Number of successful extensions: 23897
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 296
Number of HSP's successfully gapped in prelim test: 90
Number of HSP's that attempted gapping in prelim test: 15857
Number of HSP's gapped (non-prelim): 4013
length of query: 1179
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1066
effective length of database: 13,968,660
effective search space: 14890591560
effective search space used: 14890591560
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.