Guide to the Human Genome
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Search of human proteins with 148664244

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148664244 cytoskeleton associated protein 2 isoform 1 [Homo
sapiens]
         (682 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148664244 cytoskeleton associated protein 2 isoform 1 [Homo s...  1344   0.0  
gi|148664201 cytoskeleton associated protein 2 isoform 2 [Homo s...  1339   0.0  
gi|167466272 cytoskeleton associated protein 2-like [Homo sapiens]    148   2e-35
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]                    44   6e-04
gi|87299628 biorientation of chromosomes in cell division 1-like...    43   0.001
gi|37595553 ring finger protein 111 [Homo sapiens]                     42   0.002
gi|114431248 hypothetical protein LOC205717 [Homo sapiens]             42   0.002
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             41   0.004
gi|62241003 cardiomyopathy associated 5 [Homo sapiens]                 41   0.004
gi|34452686 ring finger protein, LIM domain interacting [Homo sa...    40   0.005
gi|34452684 ring finger protein, LIM domain interacting [Homo sa...    40   0.005
gi|83367077 mucin 16 [Homo sapiens]                                    40   0.005
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    40   0.007
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    40   0.007
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]                         40   0.009
gi|24431975 hypothetical protein LOC26148 [Homo sapiens]               40   0.009
gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]                       39   0.012
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]                       39   0.012
gi|45269141 multimerin 1 [Homo sapiens]                                39   0.016
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         39   0.016
gi|30795204 histone deacetylase 9 isoform 5 [Homo sapiens]             38   0.027
gi|18379328 WW domain-containing adapter with a coiled-coil regi...    38   0.035
gi|18379332 WW domain-containing adapter with a coiled-coil regi...    38   0.035
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]        38   0.035
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit...    37   0.060
gi|11225260 DNA topoisomerase I [Homo sapiens]                         37   0.079
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]     37   0.079
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ...    37   0.079
gi|150456436 hypothetical protein LOC55719 isoform 1 [Homo sapiens]    37   0.079
gi|209915547 hypothetical protein LOC55719 isoform 2 [Homo sapiens]    37   0.079

>gi|148664244 cytoskeleton associated protein 2 isoform 1 [Homo
           sapiens]
          Length = 682

 Score = 1344 bits (3478), Expect = 0.0
 Identities = 682/682 (100%), Positives = 682/682 (100%)

Query: 1   MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSRDQRVVTS 60
           MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSRDQRVVTS
Sbjct: 1   MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSRDQRVVTS 60

Query: 61  EDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKP 120
           EDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKP
Sbjct: 61  EDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKP 120

Query: 121 KDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRG 180
           KDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRG
Sbjct: 121 KDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRG 180

Query: 181 QIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTK 240
           QIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTK
Sbjct: 181 QIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTK 240

Query: 241 FVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVK 300
           FVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVK
Sbjct: 241 FVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVK 300

Query: 301 TSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPK 360
           TSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPK
Sbjct: 301 TSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPK 360

Query: 361 ETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFTE 420
           ETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFTE
Sbjct: 361 ETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFTE 420

Query: 421 KVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENII 480
           KVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENII
Sbjct: 421 KVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENII 480

Query: 481 AIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGVD 540
           AIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGVD
Sbjct: 481 AIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGVD 540

Query: 541 VDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYLQ 600
           VDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYLQ
Sbjct: 541 VDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYLQ 600

Query: 601 SVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGRE 660
           SVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGRE
Sbjct: 601 SVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGRE 660

Query: 661 TDAFVCRPNAALCRVYYEADTT 682
           TDAFVCRPNAALCRVYYEADTT
Sbjct: 661 TDAFVCRPNAALCRVYYEADTT 682


>gi|148664201 cytoskeleton associated protein 2 isoform 2 [Homo
           sapiens]
          Length = 683

 Score = 1339 bits (3466), Expect = 0.0
 Identities = 682/683 (99%), Positives = 682/683 (99%), Gaps = 1/683 (0%)

Query: 1   MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSS-RDQRVVT 59
           MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSS RDQRVVT
Sbjct: 1   MSTPAVPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSSRDQRVVT 60

Query: 60  SEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHK 119
           SEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHK
Sbjct: 61  SEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHK 120

Query: 120 PKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYR 179
           PKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYR
Sbjct: 121 PKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYR 180

Query: 180 GQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATT 239
           GQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATT
Sbjct: 181 GQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATT 240

Query: 240 KFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSV 299
           KFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSV
Sbjct: 241 KFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSV 300

Query: 300 KTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQP 359
           KTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQP
Sbjct: 301 KTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQP 360

Query: 360 KETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFT 419
           KETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFT
Sbjct: 361 KETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFT 420

Query: 420 EKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENI 479
           EKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENI
Sbjct: 421 EKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENI 480

Query: 480 IAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGV 539
           IAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGV
Sbjct: 481 IAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGV 540

Query: 540 DVDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYL 599
           DVDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYL
Sbjct: 541 DVDPEKLEMESKLHRNLLFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYL 600

Query: 600 QSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGR 659
           QSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGR
Sbjct: 601 QSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCVSSLEQLTELGR 660

Query: 660 ETDAFVCRPNAALCRVYYEADTT 682
           ETDAFVCRPNAALCRVYYEADTT
Sbjct: 661 ETDAFVCRPNAALCRVYYEADTT 683


>gi|167466272 cytoskeleton associated protein 2-like [Homo sapiens]
          Length = 745

 Score =  148 bits (373), Expect = 2e-35
 Identities = 130/504 (25%), Positives = 226/504 (44%), Gaps = 72/504 (14%)

Query: 185 SKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVST 244
           SK+ S +KP+ VK+       +     P  TK +    +   VK  +     +       
Sbjct: 287 SKVQSSKKPV-VKNIKDIKVNRSQYERPNETKIRSYPVTEQRVKHTKPRTYPS------- 338

Query: 245 TSQNTQLVRPPIRSHHSNTRDTVKQG---ISRTSANVTIRKGPHEKELL---QSKTALSS 298
                 L++    + H N +   K     I +TS  +   K   ++  L   +  +A+ S
Sbjct: 339 ------LLQGEYNNRHPNIKQDQKSSQVCIPQTSCVLQKSKAISQRPNLTVGRFNSAIPS 392

Query: 299 VKTSSSQGIIRNKTLSRSIASEVIARPASLSN----DKLMEKSEPVDQRRHTAGKAIVDS 354
             +    G   NK  +     +     + L      +  + K+ P  Q   T       +
Sbjct: 393 TPSIRPNGTSGNKHNNNGFQQKAQTLDSKLKKAVPQNHFLNKTAPKTQADVTTVNGTQTN 452

Query: 355 RSAQPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDE 414
            + + K T+E+R+ +L EW+  KG+  KRPP  + T+ +   +      SFW ++ +E+E
Sbjct: 453 PNIKKKATAEDRRKQLEEWQKSKGKTYKRPPMELKTKRKVIKEMNI---SFWKSIEKEEE 509

Query: 415 QRL----FTEKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIE 470
           ++      + K+NNT +ECLNLI  G P  +IL    +++ +IP+A+K  K+WIC A + 
Sbjct: 510 EKKAQLELSSKINNTLTECLNLIEGGVPSNEIL----NILSSIPEAEKFAKFWICKAKLL 565

Query: 471 PITSPIENIIAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVK 530
                 + +I +YE+AI  GA PI+E+R  +++IL   ++    +         S   V 
Sbjct: 566 ASKGTFD-VIGLYEEAIKNGATPIQELRKVVLNILQDSNRTTEGI--------TSDSLVA 616

Query: 531 EVSIEDTGVDVDPEKLEMESKLHRNLLFQDC--EKEQDNKTKDPTHDVKTPNTETRTSCL 588
           E SI  T V+   +K+E           + C   KE++  T  P    +    E      
Sbjct: 617 ETSI--TSVEELAKKMES---------VKSCLSPKEREQVTATP----RIAKAEQHNYPG 661

Query: 589 IKYNVSTTPYLQSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCV 648
           IK  +   P +  + +           +++KF+TPVRRS R++   S+ P+ML++H   V
Sbjct: 662 IKLQIGPIPRINGMPE----------VQDMKFITPVRRSSRIERAVSRYPEMLQEHDLVV 711

Query: 649 SSLEQLTELGRETDAFVCRPNAAL 672
           +SL++L E+  ET  F+ R N AL
Sbjct: 712 ASLDELLEV-EETKCFIFRRNEAL 734


>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
          Length = 1163

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 42/164 (25%), Positives = 72/164 (43%), Gaps = 14/164 (8%)

Query: 59  TSEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTH 118
           T E Q Q   KV     +    E+  R +ESK      K+    KPS+   +S       
Sbjct: 749 TREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQ--SAA 806

Query: 119 KPKDSNQTPHLLLTEDDPQSQH----MTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPV 174
           K KD   +P   +   DP+++H     T+SQ+  LK++S   + T+   K  ++  K+  
Sbjct: 807 KEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQ-- 864

Query: 175 LGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQ 218
                 +  + K +S  K ++ K  SS++    SA    ++KP+
Sbjct: 865 ------KKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPR 902



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 52/252 (20%), Positives = 99/252 (39%), Gaps = 27/252 (10%)

Query: 12  LPPSQRAQSAFKEQRRQKLK------EHLLRRKTLFAYKQENEMLSSRDQRVVTSEDQVQ 65
           LPPS +    + E  R  +K      E    R+ +F+  +E E+LS   +     +D+  
Sbjct: 659 LPPSSQTPK-YPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSE----PDDRYP 713

Query: 66  EGTKV-LKLKTKMADKENMK-RPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDS 123
              K+ L L T++  K   +  P + +   V  KH    +       S      HK +D 
Sbjct: 714 LIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDD 773

Query: 124 NQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIV 183
           N+          P+++          KN++  K  +  +  + +   +K +L S  G  V
Sbjct: 774 NRASE----SKKPKTED---------KNSAGHKPSSNRESSKQSAAKEKDLLPSPAGP-V 819

Query: 184 QSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVS 243
            SK        + +  S +++ K S+   K T     N+SS + +       ++++K V 
Sbjct: 820 PSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVK 879

Query: 244 TTSQNTQLVRPP 255
             + ++    PP
Sbjct: 880 EKAPSSSSNCPP 891


>gi|87299628 biorientation of chromosomes in cell division 1-like
           [Homo sapiens]
          Length = 3051

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 81/422 (19%), Positives = 155/422 (36%), Gaps = 68/422 (16%)

Query: 24  EQRRQKLKEHLLRRKTL---FAYKQENEMLSSRDQRVVTSEDQVQEGTKVLKLKTKMADK 80
           E +  ++KE L  RK L    A  ++ +  S   +     + Q +E +K     ++  +K
Sbjct: 550 EPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEK 609

Query: 81  ENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTE------- 133
           E +    E K+   V     P KP+  L+ S  V+D +K +   +  H   T        
Sbjct: 610 EKISSSKELKH---VHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTPVIMEG 666

Query: 134 ---------------------DDPQSQHMTLSQAFHLKNNSK---------KKQMTTEKQ 163
                                ++PQ Q  TL    HLK +           KK++ + K+
Sbjct: 667 VQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKE 726

Query: 164 KQD----ANMPKKPVLGSYRGQIV-----QSKINSFRKPLQVKD--ESSAATKKLSATIP 212
           K +     +  K  V   Y+G  +     +++++S  K L+V++  +  +   KLS+   
Sbjct: 727 KPEREKTPSEDKLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLSSDDK 786

Query: 213 KATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGIS 272
              K +  N   ++V           ++++  T +N +      +    +   T  +  S
Sbjct: 787 TERKSKHRNERKLSVLGKDGK---PVSEYIIKTDENVRKENNK-KERRLSAEKTKAEHKS 842

Query: 273 RTSANVTIRKG-----PHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPAS 327
           R S++  I+K       H   L +   + S  K       + +      +  +   R  S
Sbjct: 843 RRSSDSKIQKDSLGSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKS 902

Query: 328 LSNDKLMEKSEPVDQRR-----HTAGKAIVDSRSAQPKETSEERKARLSEWKAGKGRVLK 382
           L  +KL+ KS+   Q +      T  +     ++  PK   E+        K  K +V  
Sbjct: 903 LLEEKLVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVED 962

Query: 383 RP 384
           +P
Sbjct: 963 KP 964


>gi|37595553 ring finger protein 111 [Homo sapiens]
          Length = 986

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 54/301 (17%), Positives = 111/301 (36%), Gaps = 23/301 (7%)

Query: 11  QLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSRDQRVVTSEDQVQEG--- 67
           +LP  +R       QR QK KE +L ++      ++ E+L+ R   ++ S     E    
Sbjct: 209 RLPCRKRFVKNNSSQRTQKQKERILMQR------KKREVLARRKYALLPSSSSSSENDLS 262

Query: 68  TKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTP 127
           ++     +   +++     +E+  N        P  PS  +    VVI+           
Sbjct: 263 SESSSSSSTEGEEDLFVSASENHQNN-------PAVPSGSIDEDVVVIEASSTPQVTANE 315

Query: 128 HLLLTEDDPQSQHMTLSQAFHLKNN-SKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSK 186
            + +T  D + + +T+ +++  ++     +   ++     A+ P++P   S    ++Q  
Sbjct: 316 EINVTSTDSEVEIVTVGESYRSRSTLGHSRSHWSQGSSSHASRPQEPRNRSRISTVIQPL 375

Query: 187 INSFRK--PLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVST 244
             +  +   L V ++        SA +        +N S+ +     S   +A T    +
Sbjct: 376 RQNAAEVVDLTVDEDEPTVVPTTSARMESQATSASINNSNPSTSEQASDTASAVTSSQPS 435

Query: 245 TSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSS 304
           T   T        + +S T  ++     RT+++     GP     L S     S    SS
Sbjct: 436 TVSETSAT----LTSNSTTGTSIGDDSRRTTSSAVTETGPPAMPRLPSCCPQHSPCGGSS 491

Query: 305 Q 305
           Q
Sbjct: 492 Q 492


>gi|114431248 hypothetical protein LOC205717 [Homo sapiens]
          Length = 2245

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 67/303 (22%), Positives = 111/303 (36%), Gaps = 34/303 (11%)

Query: 93  TVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNN 152
           T  GKH + + P     +++    T     SNQ P  +       +    +S +      
Sbjct: 627 TFGGKHLVHILPRPSSLSASNSTQTFSVTMSNQQPQTISLNGQLFALQPVMSSSGTTNQT 686

Query: 153 SKKKQMTTEKQKQDANMPKKP--VLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSAT 210
             +    T  +  + N+       L S    I Q    S  + L +   +++ T   S T
Sbjct: 687 PMQIIQPTTSEDPNTNVALNTFGALASLNQSISQMAGQSCVQ-LSISQPANSQTAANSQT 745

Query: 211 IPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSN-------- 262
              A       T++  V ++ S+ + +T   VST+S NT    P ++S   N        
Sbjct: 746 TT-ANCVSLTTTAAPPVTTDSSATLASTYNLVSTSSMNTVACLPNMKSKRLNKKPGGRKH 804

Query: 263 ------------TRDTVKQGISRTSANVTIRKGPHEKELLQSKTA-LSSVKTSSSQGIIR 309
                        RD  K     T  +    + P    LL+S  A L SV  S +  +  
Sbjct: 805 LAANKSACPLNSVRDVSKLDCPNTEGSA---EPPCNDGLLESFPAVLPSVSVSQANSVSV 861

Query: 310 NKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTA---GKAIVDSRSAQP---KETS 363
           + + S  + S     P S+S  K  EKS P  Q   T+     A   S+ + P   +ETS
Sbjct: 862 SASHSLGVLSSESLIPESVSKSKSAEKSSPPSQESVTSEHFAMAAAKSKDSTPNLQQETS 921

Query: 364 EER 366
           +++
Sbjct: 922 QDK 924


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 109/579 (18%), Positives = 233/579 (40%), Gaps = 68/579 (11%)

Query: 8    QDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEM-----LSSRDQRVVTSED 62
            Q  QL    + QS   +Q ++ L + +  +K      Q+  +     ++  + ++  S++
Sbjct: 576  QVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKE 635

Query: 63   QVQEGTKVLKLKTKM---ADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHK 119
            +V +    +K KT++   A+     + A+ +N+    ++ +  K   EL   T  +D   
Sbjct: 636  KVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDK-QQELNKITTQLDQVT 694

Query: 120  PKDSNQTPHLLLTED---DPQSQHMTLSQ-------------AFHLKNNSKKKQMTTEKQ 163
             K  ++  H    E    + + ++++L Q             A  L+  + K+Q   + Q
Sbjct: 695  AKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQ 754

Query: 164  KQ---DANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDES--SAATKKLSATIPKATKPQ 218
            +Q   + ++  +    S + ++ +  ++S R  LQ K E+  S   K       K    Q
Sbjct: 755  QQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQ 814

Query: 219  PVNTSSVTVKSNRS--SNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSA 276
               T S   K      +N   TT    T  Q  ++ +  + +  S    TVK  +S+ S 
Sbjct: 815  DFETLSQETKIQHEELNNRIQTTV---TELQKVKMEKEALMTELS----TVKDKLSKVSD 867

Query: 277  NVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEK 336
            ++   K   EKE  + K A+  ++ +  +   + +    +   E      SL  +K  E 
Sbjct: 868  SLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEK--EA 925

Query: 337  SEPVDQRRHTAGKAIVDSRSAQPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAG 396
            S  +    ++  + ++ +++   +   EE++ +      G    LK+       Q E A 
Sbjct: 926  SHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQ------GNINELKQSSEQKKKQIE-AL 978

Query: 397  QNEKPVGSFWTTMAEEDEQRLFTEKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDA 456
            Q E  +     T  E   Q+  T+      +E          KE I V  N+  K+    
Sbjct: 979  QGELKIAVLQKTELENKLQQQLTQAAQELAAE----------KEKISVLQNNYEKSQETF 1028

Query: 457  KKLVKYWI-----CLALIEPITSPIENIIAIYEKAILAGAQPIEEMRHTIVDILTMKS-- 509
            K+L   +       LA  + + S +E  +++ ++ +++    I      I ++ T K+  
Sbjct: 1029 KQLQSDFYGRESELLATRQDLKS-VEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATL 1087

Query: 510  -QEKANLGENMEKSCASKEEV-KEVSIEDTGVDVDPEKL 546
             Q+ A   + +++ C + +++ KE S+++  +  +  KL
Sbjct: 1088 EQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKL 1126


>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
          Length = 4069

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 76/393 (19%), Positives = 158/393 (40%), Gaps = 45/393 (11%)

Query: 14   PSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSRDQRVVTSEDQVQEGTKVLKL 73
            P + ++ +  +    +LK+ +    +L   ++E ++   R       +D ++  +  L  
Sbjct: 2413 PVEESKGSLIDFSEDRLKKEMQNPTSLKISEEETKL---RSVSPTEKKDNLENRSYTLAE 2469

Query: 74   KTKMADKENMKRPAESKNNTVVGKHCIPL-KPSNELTNS---TVVIDTHKPKDSNQTPHL 129
            K  +A+K+N   P E +++  +GK  I L   S EL  S    +    ++ +D N+ P +
Sbjct: 2470 KKVLAEKQNSVAPLELRDSNEIGKTQITLGSRSTELKESKADAMPQHFYQNEDYNERPKI 2529

Query: 130  LLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSKINS 189
            ++  +  + +    +Q + L    K+++          +M ++  + S    + +++  S
Sbjct: 2530 IVGSEKEKGEEKE-NQVYVLSEGKKQQEHQPYSVNVAESMSRESDI-SLGHSLGETQSFS 2587

Query: 190  FRKPLQVKDESSAATKKLSATIPKA----TKPQPVNTSSVTVKSNRSSNMTATT-----K 240
              K   V ++S A   +    I +A    T+P P+  S V V+  ++    A +     +
Sbjct: 2588 LVKATSVTEKSEAMLAEAHPEIREAKAVGTQPHPLEESKVLVEKTKTFLPVALSCRDEIE 2647

Query: 241  FVSTTSQNTQLVRPPIRS--HHSN------------------TRDTVKQGISRTSANVTI 280
              S + +   ++    R    HS                   T++TVKQG    +     
Sbjct: 2648 NHSLSQEGNLVLEKSSRDMPDHSEEKEQFRESELSKGGSVDITKETVKQGFQEKAVGTQP 2707

Query: 281  RKGPHEKELLQ-SKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEP 339
            R     K L++ +KT L  V +   +  I N +LS+   + V+ + +    D   EK + 
Sbjct: 2708 RPLEESKVLVEKTKTFLPVVLSCHDE--IENHSLSQE-GNLVLEKSSRDMPDHSEEKEQF 2764

Query: 340  VDQRRHTAGKAIVDSRSAQ---PKETSEERKAR 369
             +      G   +   S +   P + SE   AR
Sbjct: 2765 KESELWKGGSVDITKESMKEGFPSKESERTLAR 2797



 Score = 33.9 bits (76), Expect = 0.51
 Identities = 40/183 (21%), Positives = 72/183 (39%), Gaps = 10/183 (5%)

Query: 36   RRKTLFAYKQENEMLSSRDQRVVTSEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVV 95
            ++  LF+   ++E L S  ++ + S  +V E    L L      K+       S+N +  
Sbjct: 1494 KQDLLFSTVCDSERLVSSQKKSLMSTSEVLEPEHELPLSLWGEIKKKETELPSSQNVSPA 1553

Query: 96   GKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKK 155
             KH IP     E  +S+  ++      S   P LLL  DD     + +S        S+K
Sbjct: 1554 SKHIIPKGKDEETASSSPELEN---LASGLAPTLLLLSDDKNKPAVEVSSTAQGDFPSEK 1610

Query: 156  K-----QMTTEKQKQDANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSAT 210
            +     +++ E +K+D   P +P+     G    S +      +  K   S  T+   + 
Sbjct: 1611 QDVALAELSLEPEKKD--KPHQPLELPNAGSEFSSDLGRQSGSIGTKQAKSPITETEDSV 1668

Query: 211  IPK 213
            + K
Sbjct: 1669 LEK 1671



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 55/287 (19%), Positives = 101/287 (35%), Gaps = 22/287 (7%)

Query: 8    QDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSRDQRVVTSEDQVQEG 67
            +DL LPPS       + +         +    + A KQ+ +     +   +       E 
Sbjct: 1076 EDLSLPPSTDKSEKAEIKPEIPTTSTSVSEYLILAQKQKTQAYLEPESEDLIPSHLTSEV 1135

Query: 68   TKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTP 127
             K  +  +          PA+S   ++V +   P  P + L +S   I     K+   T 
Sbjct: 1136 EKGEREASSSVAAIPAALPAQS---SIVKEETKPASPHSVLPDSVPAIK----KEQEPTA 1188

Query: 128  HLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQK---QDANMPKKPVLGSYRGQIVQ 184
             L L   D Q     + +   + ++ +     ++ QK   Q  N+P+  +  S    +V 
Sbjct: 1189 ALTLKAADEQMALSKVRKEEIVPDSQEATAHVSQDQKMEPQPPNVPESEMKYSVLPDMVD 1248

Query: 185  SKINSFRKPLQVKDESSAATKKLSATIPKATKPQ----------PVNTSSVTVKSNRSSN 234
                  +  L +   S    +KLS   P+  KP           P   S+V ++    S 
Sbjct: 1249 EPKKGVKPKLVLNVTSELEQRKLSKNEPEVIKPYSPLKETSLSGPEALSAVKMEMKHDSK 1308

Query: 235  MTATTKFVSTTSQNT--QLVRPPIRSHHSNTRDTVKQGISRTSANVT 279
            +T T   + + S     Q+   P     S   + +K+ I  +S+  T
Sbjct: 1309 ITTTPIVLHSASSGVEKQVEHGPPALAFSALSEEIKKEIEPSSSTTT 1355


>gi|34452686 ring finger protein, LIM domain interacting [Homo
           sapiens]
          Length = 624

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 47/206 (22%), Positives = 84/206 (40%), Gaps = 10/206 (4%)

Query: 165 QDANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSA-TIPKATKPQPVNTS 223
           Q++    +P      G+ V++  NS R+    + ES++A    S     +A    P    
Sbjct: 150 QNSENENEPSARRSSGENVEN--NSQRQVENPRSESTSARPSRSERNSTEALTEVPPTRG 207

Query: 224 SVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVK-------QGISRTSA 276
               +S    +     +   + S    +   P RSHHS +  T +       +G SRT  
Sbjct: 208 QRRARSRSPDHRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRH 267

Query: 277 NVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEK 336
           +VT+R+     ELL      +S   ++SQG   + T +   ++    RP ++  D  + +
Sbjct: 268 HVTLRQQISGPELLSRGLFAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRR 327

Query: 337 SEPVDQRRHTAGKAIVDSRSAQPKET 362
             P + R+  +  +   SRS  P  T
Sbjct: 328 VRPGEYRQRDSIASRTRSRSQTPNNT 353


>gi|34452684 ring finger protein, LIM domain interacting [Homo
           sapiens]
          Length = 624

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 47/206 (22%), Positives = 84/206 (40%), Gaps = 10/206 (4%)

Query: 165 QDANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSA-TIPKATKPQPVNTS 223
           Q++    +P      G+ V++  NS R+    + ES++A    S     +A    P    
Sbjct: 150 QNSENENEPSARRSSGENVEN--NSQRQVENPRSESTSARPSRSERNSTEALTEVPPTRG 207

Query: 224 SVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVK-------QGISRTSA 276
               +S    +     +   + S    +   P RSHHS +  T +       +G SRT  
Sbjct: 208 QRRARSRSPDHRRTRARAERSRSPLHPMSEIPRRSHHSISSQTFEHPLVNETEGSSRTRH 267

Query: 277 NVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEK 336
           +VT+R+     ELL      +S   ++SQG   + T +   ++    RP ++  D  + +
Sbjct: 268 HVTLRQQISGPELLSRGLFAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRR 327

Query: 337 SEPVDQRRHTAGKAIVDSRSAQPKET 362
             P + R+  +  +   SRS  P  T
Sbjct: 328 VRPGEYRQRDSIASRTRSRSQTPNNT 353


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 51/201 (25%), Positives = 88/201 (43%), Gaps = 37/201 (18%)

Query: 181  QIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTK 240
            +I +  + S   P Q       +T+ +S     +T P    ++ +T+ ++ +S + ATT+
Sbjct: 7862 EISKEDVTSIPGPAQSTISPDISTRTVSWF---STSPVMTESAEITMNTH-TSPLGATTQ 7917

Query: 241  FVST--TSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHE---------KEL 289
              ST  TS  T L           T  T+ QG S +  +  +R+GP +         ++ 
Sbjct: 7918 GTSTLDTSSTTSLTM---------THSTISQGFSHSQMSTLMRRGPEDVSWMSPPLLEKT 7968

Query: 290  LQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSN------DKLMEKSEPVDQR 343
              S + +SS  T+S   +  + TL  SI+S  +   + L++      D L + SEPV   
Sbjct: 7969 RPSFSLMSSPATTSPSPV--SSTLPESISSSPLPVTSLLTSGLAKTTDMLHKSSEPV--- 8023

Query: 344  RHTAGKAIVDSRSAQPKETSE 364
              T   A + S S +   TSE
Sbjct: 8024 --TNSPANLSSTSVEILATSE 8042



 Score = 37.0 bits (84), Expect = 0.060
 Identities = 44/183 (24%), Positives = 73/183 (39%), Gaps = 20/183 (10%)

Query: 217  PQPVNTSSVTVKSNRSSNMT---ATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISR 273
            P  V   SVT K+  S  +T     T  +++T   +   R   +S  S T   ++  IS 
Sbjct: 9238 PSSVLADSVTTKATSSMGITYPTGDTNVLTSTPAFSDTSRIQTKSKLSLTPGLMETSISE 9297

Query: 274  TSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKL 333
             +++ T           +  T LSSV T ++  + R + +S S  S      +++S+D  
Sbjct: 9298 ETSSAT-----------EKSTVLSSVPTGATTEVSRTEAISSSRTSIPGPAQSTMSSDTS 9346

Query: 334  MEK----SEPVDQRRHT--AGKAIVDSRSAQPKETSEERKARLSEWKAGKGRVLKRPPNS 387
            ME     S P+ ++  T  A         A  + T     +  + W        +R P S
Sbjct: 9347 METITRISTPLTRKESTDMAITPKTGPSGATSQGTFTLDSSSTASWPGTHSATTQRFPQS 9406

Query: 388  VVT 390
            VVT
Sbjct: 9407 VVT 9409



 Score = 33.1 bits (74), Expect = 0.87
 Identities = 47/205 (22%), Positives = 87/205 (42%), Gaps = 15/205 (7%)

Query: 126 TPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKK--PVLGSYRGQIV 183
           +P   L  ++  + H T  +      N+    + T    +++ M     P LG      +
Sbjct: 408 SPSTTLVSEETNTHHSTSGKETEGTLNTSMTPLETSAPGEESEMTATLVPTLGF---TTL 464

Query: 184 QSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVS 243
            SKI   R P QV   SS  T++L  T   + + Q  +T++        +  ++T+K  S
Sbjct: 465 DSKI---RSPSQVS--SSHPTRELRTTGSTSGR-QSSSTAAHGSSDILRATTSSTSKASS 518

Query: 244 TTSQNT-QLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTS 302
            TS++T Q    P  +    T  ++K      S +V     P    +    +  +++KTS
Sbjct: 519 WTSESTAQQFSEPQHTQWVETSPSMKTERPPASTSVA---APITTSVPSVVSGFTTLKTS 575

Query: 303 SSQGIIRNKTLSRSIASEVIARPAS 327
           S++GI   +T + ++  E  A P +
Sbjct: 576 STKGIWLEETSADTLIGESTAGPTT 600



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 41/178 (23%), Positives = 76/178 (42%), Gaps = 18/178 (10%)

Query: 198  DESSAATKKLSA---TIPK---ATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQL 251
            +E+S+ +  +S+   T P    +T PQ + +S + V +  +S +  TT  + TTS  +  
Sbjct: 5330 EETSSVSSLMSSPAMTSPSPVSSTSPQSIPSSPLPVTALPTSVLVTTTDVLGTTSPESVT 5389

Query: 252  VRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNK 311
              PP  S  ++ R    +  + T A +      H      + TA+++V TS S    ++ 
Sbjct: 5390 SSPPNLSSITHERPATYKDTAHTEAAM------HH----STNTAVTNVGTSGSGHKSQSS 5439

Query: 312  TLSRSIASEV--IARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEERK 367
             L+ S  S+   +    S   D  +  S P   + +        S S + +E+S   K
Sbjct: 5440 VLADSETSKATPLMSTTSTLGDTSVSTSTPNISQTNQIQTEPTASLSPRLRESSTSEK 5497



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 46/196 (23%), Positives = 74/196 (37%), Gaps = 31/196 (15%)

Query: 123  SNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQI 182
            S  TP++  T         +LS      + S+K   TTE     + +P   +  + R +I
Sbjct: 5465 STSTPNISQTNQIQTEPTASLSPRLRESSTSEKTSSTTETNTAFSYVPTGAITQASRTEI 5524

Query: 183  VQSK--INSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTK 240
              S+  I+   +P    D S+    +L  +        P+ T        +S+ MT TT+
Sbjct: 5525 SSSRTSISDLDRPTIAPDISTGMITRLFTS--------PIMT--------KSAEMTVTTQ 5568

Query: 241  FVSTTSQNTQLVRPPIRS---HHSNTRDTVKQGI---------SRTSANVTIRKGPHEKE 288
              +T    +Q + P   S       T  TV QG          SRT  +V+    P  +E
Sbjct: 5569 -TTTPGATSQGILPWDTSTTLFQGGTHSTVSQGFPHSEITTLRSRTPGDVSWMTTPPVEE 5627

Query: 289  LLQSKTALSSVKTSSS 304
                 + +S   TS S
Sbjct: 5628 TSSGFSLMSPSMTSPS 5643



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 58/284 (20%), Positives = 108/284 (38%), Gaps = 36/284 (12%)

Query: 50   LSSRDQRVVTSEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELT 109
            L S   ++ T+ + +++  K+    T +A        +E ++ + V  +  P K ++ + 
Sbjct: 6566 LGSTSHKIPTTSEDIKDTEKMYP-STNIAVTNVGTTTSEKESYSSVPAYSEPPKVTSPMV 6624

Query: 110  NS----TVVIDTHKPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQ--MTTEKQ 163
             S      ++ T  P  S       +T  + +S   T S A  LK  S  +   ++TEK 
Sbjct: 6625 TSFNIRDTIVSTSMPGSSE------ITRIEMES---TFSLAHGLKGTSTSQDPIVSTEKS 6675

Query: 164  KQDANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTS 223
                 +       S R ++  S+  S   P    D S+ +    +  IP           
Sbjct: 6676 AVLHKLTTGATETS-RTEVASSRRTSIPGP----DHSTESPDISTEVIPSLP-------- 6722

Query: 224  SVTVKSNRSSNMTATTKF---VSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTI 280
             +++    SSNMT  T+    + +TSQ T  +  P  S  + T     Q    +     +
Sbjct: 6723 -ISLGITESSNMTIITRTGPPLGSTSQGTFTLDTPTTSSRAGTHSMATQEFPHSEMTTVM 6781

Query: 281  RKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIAR 324
             K P   E+L      S  KTS S  ++ +  ++    S  + +
Sbjct: 6782 NKDP---EILSWTIPPSIEKTSFSSSLMPSPAMTSPPVSSTLPK 6822



 Score = 31.2 bits (69), Expect = 3.3
 Identities = 69/329 (20%), Positives = 125/329 (37%), Gaps = 38/329 (11%)

Query: 47   NEMLSSRDQRVVTSEDQVQEGTKVLKLKTKMADKE-NMKRPAESKNNTVVGKHCIPLKPS 105
            +E L++      T    V E T    ++T  A +E     P  S+   V+     P+  S
Sbjct: 9497 DESLAASKATTETEAIHVFENTAASHVETTSATEELYSSSPGFSEPTKVIS----PVVTS 9552

Query: 106  NELTNSTVVIDTHKPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQ 165
            + + ++  ++ T  P  S       +T  + +S   +L+        S+    +TE    
Sbjct: 9553 SSIRDN--MVSTTMPGSSG------ITRIEIESMS-SLTPGLRETRTSQDITSSTETSTV 9603

Query: 166  DANMPKKPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSV 225
               MP        R +++ S   S   P Q     S  +  +S  +       P+ T S 
Sbjct: 9604 LYKMPSGATPEVSRTEVMPSSRTSIPGPAQ-----STMSLDISDEVVTRLSTSPIMTESA 9658

Query: 226  TVKSNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPH 285
             +       +T  T +   TSQ T L      +  S T  T+ QG+S +     + +GP 
Sbjct: 9659 EI------TITTQTGYSLATSQVT-LPLGTSMTFLSGTHSTMSQGLSHSEMTNLMSRGPE 9711

Query: 286  E--------KELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKS 337
                      E  +S ++L+S+  ++S   + +  L  S +S +     SL    L++ +
Sbjct: 9712 SLSWTSPRFVETTRSSSSLTSLPLTTSLSPVSSTLLDSSPSSPLPV--TSLILPGLVKTT 9769

Query: 338  EPVD--QRRHTAGKAIVDSRSAQPKETSE 364
            E +D      T+    + S S +   TSE
Sbjct: 9770 EVLDTSSEPKTSSSPNLSSTSVEIPATSE 9798



 Score = 31.2 bits (69), Expect = 3.3
 Identities = 38/158 (24%), Positives = 60/158 (37%), Gaps = 19/158 (12%)

Query: 181   QIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNR---SSNMTA 237
             +I  S    +R    +  ESS    +L       T  QP  TSS  +   R   S  +  
Sbjct: 10350 EITSSSATPYRVDTSLGTESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGT 10409

Query: 238   TTKFVSTTSQNTQLVRP----------PIRSHHSNTRDTVKQGISRTSANVTIRKGPHEK 287
              T      S +T+L R           P  + H  T   VK    +TS +    KG H  
Sbjct: 10410 VTSAYQVPSLSTRLTRTDGIMEHITKIPNEAAHRGTIRPVKG--PQTSTSPASPKGLHTG 10467

Query: 288   ELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARP 325
                + +T  +++KT+++      KT SR+  +  +  P
Sbjct: 10468 GTKRMETTTTALKTTTT----ALKTTSRATLTTSVYTP 10501


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 70/334 (20%), Positives = 130/334 (38%), Gaps = 42/334 (12%)

Query: 53  RDQRVVTSEDQVQEGTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNST 112
           + Q V +SED   E           + +E  K P ++    VV K      P+ +   S+
Sbjct: 315 KQQPVESSEDSSDESDS--------SSEEEKKPPTKA----VVSKATTKPPPAKKAAESS 362

Query: 113 VVIDTHKPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQK-QDANMPK 171
                    DS+ +       D  +        A   KN+S K  +TT+    + A  PK
Sbjct: 363 --------SDSSDS-------DSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPK 407

Query: 172 KPVLGSYRGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNR 231
           +PV G  +  ++  K +S     +        TKK+ AT    TKP+    +++++ + +
Sbjct: 408 QPVGGGQK--LLTRKADSSSSEEESSSSEEEKTKKMVAT----TKPKATAKAALSLPAKQ 461

Query: 232 SSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQ 291
           +   +  +   S +S + +      +S        V  G +  S   + +KG  E     
Sbjct: 462 APQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGG-AAPSKPASAKKGKAE----S 516

Query: 292 SKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPA-SLSNDKLMEKSEPVDQRRHTAGKA 350
           S ++ S   +   +  ++ K   R  A +     A +  N K  + SE  ++ +  A  A
Sbjct: 517 SNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKA--A 574

Query: 351 IVDSRSAQPKETSEERKARLSEWKAGKGRVLKRP 384
           +V S+S   K+  +   A+ +E    K   L+ P
Sbjct: 575 VVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTP 608


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 40.0 bits (92), Expect = 0.007
 Identities = 77/405 (19%), Positives = 149/405 (36%), Gaps = 47/405 (11%)

Query: 10  LQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSRDQRVVT---SEDQVQE 66
           LQ PP   A       R Q    HL   KT   + ++ E   S+D++  T    + + + 
Sbjct: 85  LQWPPIYTAA------REQTPFRHLYTSKT---HLKKAEYKKSKDEKGGTPLKKDSKKKG 135

Query: 67  GTKVLKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQT 126
           G+     ++K   +E  KR  E+           PLK S+E   S     + +    +Q 
Sbjct: 136 GSYATNPESKQIVEEKTKRQNEADKT--------PLKSSHENEQSKKSKSSSETNPESQN 187

Query: 127 PHLLLT------EDDPQSQHMTLSQAFHLKNNSKK--KQMTTEKQKQDANMPKKPVLGSY 178
              +        + D ++   T ++  H KNN KK  K+  T          +  +   +
Sbjct: 188 SKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDF 247

Query: 179 RGQIVQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTAT 238
              + QS   S      +++ S   +K  S    K TK           K N   +  A 
Sbjct: 248 LMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKD--------TKKNAKKSSDAE 299

Query: 239 TKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSS 298
           ++      ++++ V+  ++      +D  K+ + + + +     G  + E   +K     
Sbjct: 300 SEDSKDAKKDSKKVKKNVK------KDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKK 353

Query: 299 VKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAI--VDSRS 356
           +K    +     K    S  +E      + ++ + ++K+   D ++  A K     DS S
Sbjct: 354 LKKDDKKK--DTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSES 411

Query: 357 A-QPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEK 400
             + KE+ ++ K    + K    + +K    S     EP G ++K
Sbjct: 412 ELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKK 456


>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
          Length = 4377

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 67/309 (21%), Positives = 113/309 (36%), Gaps = 40/309 (12%)

Query: 75   TKMADKENMKRPAESKNNTVVGKHCIPLKP--------SNELTN----STVVIDTHKPKD 122
            T   +K+N  + +  K   V+  HC+  K         + EL      S + I    PKD
Sbjct: 3815 TCTTEKDNPVKVSSGKKTGVLQGHCVRDKQKVLGEQQKTKELIGIRQKSKLPIKATSPKD 3874

Query: 123  SNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQI 182
            +    H+  T+     Q         +  + K K +TT       +  + PV  ++R  I
Sbjct: 3875 TFPPNHMSNTKASKMKQ---------VSQSEKTKALTTSSCVDVKS--RIPVKNTHRDNI 3923

Query: 183  VQSKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFV 242
            +     + RK    + +      K      K     PV   S  V +  ++  T TT   
Sbjct: 3924 I-----AVRKACATQKQGQPEKGKAKQLPSKL----PVKVRSTCVTTTTTTATTTTTTTT 3974

Query: 243  STTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTS 302
            +TT+  T  VR               +GIS  +  +  R    EK++   ++ LS  + S
Sbjct: 3975 TTTTSCTVKVRKSQLKEVCKHSIEYFKGISGETLKLVDRLSEEEKKM---QSELSDEEES 4031

Query: 303  SSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKET 362
            +S    RN +LS +      +     + DK  E + P+  +   AG     SR   P+  
Sbjct: 4032 TS----RNTSLSETSRGGQPSVTTKSARDKKTE-AAPLKSKSEKAGSEKRSSRRTGPQSP 4086

Query: 363  SEERKARLS 371
             E    R++
Sbjct: 4087 CERTDIRMA 4095


>gi|24431975 hypothetical protein LOC26148 [Homo sapiens]
          Length = 1247

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 41/183 (22%), Positives = 73/183 (39%), Gaps = 17/183 (9%)

Query: 192  KPLQVKDESSAATKKLSATIPKA---TKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQN 248
            KP   +       K++S  +PKA   +K +    SS     N+   + A+ +  +  +  
Sbjct: 1061 KPKSTEGMKGRKGKQVSEILPKAEVQSKRKRTEGSSPPDSKNKGPTVKASKEKHADGATK 1120

Query: 249  TQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGII 308
            T   + P        RD   Q   +TS           K  +  K+A  S   S  +   
Sbjct: 1121 TPAAKRPA------ARDRSSQPPKKTSLK-------ENKVKIPKKSAGKSCPPSRKEKEN 1167

Query: 309  RNKTLSRSIASEVIARPASLSN-DKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEERK 367
             NK  S+SIASE + +PA      +   + +    R+ ++GK      +  P+ ++ +RK
Sbjct: 1168 TNKRPSQSIASETLTKPAKQKGAGESSSRPQKATNRKQSSGKTRARPSTKTPESSAAQRK 1227

Query: 368  ARL 370
             +L
Sbjct: 1228 RKL 1230


>gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]
          Length = 558

 Score = 39.3 bits (90), Expect = 0.012
 Identities = 64/367 (17%), Positives = 142/367 (38%), Gaps = 28/367 (7%)

Query: 16  QRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSRDQRVVTSEDQVQEGTKVLKLKT 75
           +R + A +E+ RQK +E  L + T          +   + +  T+  QV EG        
Sbjct: 34  ERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQV-EGDDEAAFLE 92

Query: 76  KMADKENMKRPA-------ESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPH 128
           ++A +E  ++         + + +  +    + L PS  + N T   +T + ++ +++  
Sbjct: 93  RLARREERRQKRLQEALERQKEFDPTITDASLSL-PSRRMQNDTAENETTEKEEKSESRQ 151

Query: 129 LLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSKIN 188
                ++ ++   +  Q    ++  + K+   EK++++   PK+  +G  +G+   +K+ 
Sbjct: 152 ERYEIEETETVTKSY-QKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQ 210

Query: 189 SFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQN 248
           + R+ LQ    +    +     I K  +P          K    S M     F    SQN
Sbjct: 211 AKREKLQEDKPTFKKEEIKDEKIKKDKEP----------KEEVKSFMDRKKGFTEVKSQN 260

Query: 249 TQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKEL---LQSKTALSSVKTSSSQ 305
            + +   ++    +T +T  +   R S +    +G  + E    L+          S   
Sbjct: 261 GEFMTHKLK----HTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEF 316

Query: 306 GIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEE 365
             ++ K    ++  E + +       K++E+ E   ++     K   +    + KE  E 
Sbjct: 317 EKLKQKQQEAALELEELKKKRE-ERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIER 375

Query: 366 RKARLSE 372
           R+A  +E
Sbjct: 376 RRAEAAE 382


>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
          Length = 564

 Score = 39.3 bits (90), Expect = 0.012
 Identities = 64/367 (17%), Positives = 142/367 (38%), Gaps = 28/367 (7%)

Query: 16  QRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSSRDQRVVTSEDQVQEGTKVLKLKT 75
           +R + A +E+ RQK +E  L + T          +   + +  T+  QV EG        
Sbjct: 40  ERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQV-EGDDEAAFLE 98

Query: 76  KMADKENMKRPA-------ESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPH 128
           ++A +E  ++         + + +  +    + L PS  + N T   +T + ++ +++  
Sbjct: 99  RLARREERRQKRLQEALERQKEFDPTITDASLSL-PSRRMQNDTAENETTEKEEKSESRQ 157

Query: 129 LLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSKIN 188
                ++ ++   +  Q    ++  + K+   EK++++   PK+  +G  +G+   +K+ 
Sbjct: 158 ERYEIEETETVTKSY-QKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQ 216

Query: 189 SFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQN 248
           + R+ LQ    +    +     I K  +P          K    S M     F    SQN
Sbjct: 217 AKREKLQEDKPTFKKEEIKDEKIKKDKEP----------KEEVKSFMDRKKGFTEVKSQN 266

Query: 249 TQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKEL---LQSKTALSSVKTSSSQ 305
            + +   ++    +T +T  +   R S +    +G  + E    L+          S   
Sbjct: 267 GEFMTHKLK----HTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEF 322

Query: 306 GIIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEE 365
             ++ K    ++  E + +       K++E+ E   ++     K   +    + KE  E 
Sbjct: 323 EKLKQKQQEAALELEELKKKRE-ERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIER 381

Query: 366 RKARLSE 372
           R+A  +E
Sbjct: 382 RRAEAAE 388


>gi|45269141 multimerin 1 [Homo sapiens]
          Length = 1228

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 40/189 (21%), Positives = 84/189 (44%), Gaps = 17/189 (8%)

Query: 412 EDEQRLFTEKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEP 471
           ED+ R F   +    S+ +N++     +E   +  ND+ + +    K V      +L E 
Sbjct: 365 EDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVS-----SLSED 419

Query: 472 ITSPIENIIAIYEKAILAGAQP----IEEMRHTIVDILTMKSQEKANLGENMEKSCASKE 527
           + S  + I  + E  +   AQ     ++E R T+ DI+ +++    N+ + M  +C  ++
Sbjct: 420 LESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRN-HIVNVRQEMTLTC--EK 476

Query: 528 EVKEVSIEDTGVDVDPEKLEMESKLHRNLLFQDCEK-----EQDNKTKDPTHDVKTPNTE 582
            +KE+ ++ T ++   E+    S L+   L +   K     EQ   T+  +     P  E
Sbjct: 477 PIKELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAE 536

Query: 583 TRTSCLIKY 591
           + ++ + +Y
Sbjct: 537 SVSNNVTEY 545


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 79/389 (20%), Positives = 150/389 (38%), Gaps = 52/389 (13%)

Query: 14  PSQRAQSAFKEQRRQKLKEHLLRRKTLF---AYKQENEMLSSRDQRVVTSEDQVQEGTKV 70
           P +R+    +E++R   +    R K+     A +++ +     +  V   E  VQE T  
Sbjct: 182 PRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATST 241

Query: 71  LKLKTKMADKENMKRPAES--KNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPH 128
             +  K+   E +  P E   + N+   K     +P +            + K  ++T  
Sbjct: 242 SDI-LKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSR----------SRSKSRSRTRS 290

Query: 129 LLLTEDDPQSQHMTLSQAFHLKNN-SKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSKI 187
              +   P+ +H + S+++  +   S +++ +  ++     MP  P     R  + + + 
Sbjct: 291 RSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRR- 349

Query: 188 NSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQ 247
              R    +   SS+++   S + PK  KP P  TSS   K+ R S   +  +      +
Sbjct: 350 ---RSSASLSGSSSSSSSSRSRSPPK--KP-PKRTSSPPRKTRRLSPSASPPR---RRHR 400

Query: 248 NTQLVRPPIRSHHSNT--------RDTVKQGISRTSANVTIRKG------------PHEK 287
            +    PP ++ HS T        +  V     RTS  VT  KG            P + 
Sbjct: 401 PSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKV 460

Query: 288 ELLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKS-----EPVDQ 342
           EL +S+        ++     R +   ++  S   +  +S S D+  ++S     E   +
Sbjct: 461 ELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRR 520

Query: 343 RRHTAGKAIVDSRSAQPKETSEERKARLS 371
           RRH+  ++   S   + KETS   + R S
Sbjct: 521 RRHSPSRSASPSPRKRQKETSPRGRRRRS 549


>gi|30795204 histone deacetylase 9 isoform 5 [Homo sapiens]
          Length = 1069

 Score = 38.1 bits (87), Expect = 0.027
 Identities = 67/351 (19%), Positives = 133/351 (37%), Gaps = 36/351 (10%)

Query: 6   VPQDLQLPPSQRAQSAFKEQRRQKLKEHLLRRKTLFAYKQENEMLSS----RDQRVVTSE 61
           + + L +   Q+       Q + +L+EH+  ++ L A KQ+ E+L        QR     
Sbjct: 59  IQKQLLIAEFQKQHENLTRQHQAQLQEHIKLQQELLAIKQQQELLEKEQKLEQQRQEQEV 118

Query: 62  DQVQEGTKVLKLKTKMADKENMKRPAESKNNT---VVGKHCIPLKPSNELTNSTVVIDTH 118
           ++ +   ++  L+ K   +E      E K      ++ K      P+N   +S   +  H
Sbjct: 119 ERHRREQQLPPLRGKDRGRERAVASTEVKQKLQEFLLSKSATKDTPTNGKNHS---VSRH 175

Query: 119 KPKDSNQTPHLLLTEDDP------QSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKK 172
                    H  L +  P       S   TL  A   K++   ++  +E   +  +  K+
Sbjct: 176 PKLWYTAAHHTSLDQSSPPLSGTSPSYKYTLPGAQDAKDDFPLRKTASEPNLKVRSRLKQ 235

Query: 173 PVLGSYRGQIVQSK----INSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVK 228
            V       +++ K    + SF+K +    ESS     +S++ P +    P N  + +V 
Sbjct: 236 KVAERRSSPLLRRKDGNVVTSFKKRMFEVTESS-----VSSSSPGSGPSSPNNGPTGSVT 290

Query: 229 SNRSSNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKE 288
            N +S +  T       SQ   L+       H ++ + +    S +  N+T+   P    
Sbjct: 291 ENETSVLPPTPHAEQMVSQQRILI-------HEDSMNLLSLYTSPSLPNITLGL-PAVPS 342

Query: 289 LLQSKTALSSVKTSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEP 339
            L +  +L   +   +Q + +   L       +   PAS S+  +  + +P
Sbjct: 343 QLNASNSLKEKQKCETQTLRQGVPLPGQYGGSI---PASSSHPHVTLEGKP 390


>gi|18379328 WW domain-containing adapter with a coiled-coil region
           isoform 1 [Homo sapiens]
          Length = 647

 Score = 37.7 bits (86), Expect = 0.035
 Identities = 38/134 (28%), Positives = 57/134 (42%), Gaps = 10/134 (7%)

Query: 204 TKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVR-----PPIRS 258
           T  +S     +T+ QP N S +++ S+ SS  +  +  +ST   NT  ++     PP+ S
Sbjct: 417 TSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSS 476

Query: 259 HHSNTRDTVKQG---ISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSR 315
               +   VKQG    S T   VT  K    + +       SS + S S G   N T + 
Sbjct: 477 QPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPG--PNHTSNS 534

Query: 316 SIASEVIARPASLS 329
           S AS     P + S
Sbjct: 535 SNASNATVVPQNSS 548


>gi|18379332 WW domain-containing adapter with a coiled-coil region
           isoform 3 [Homo sapiens]
          Length = 544

 Score = 37.7 bits (86), Expect = 0.035
 Identities = 38/134 (28%), Positives = 57/134 (42%), Gaps = 10/134 (7%)

Query: 204 TKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVR-----PPIRS 258
           T  +S     +T+ QP N S +++ S+ SS  +  +  +ST   NT  ++     PP+ S
Sbjct: 314 TSLISQAAQLSTQAQPSNQSPMSLTSDASSPRSYVSPRISTPQTNTVPIKPLISTPPVSS 373

Query: 259 HHSNTRDTVKQG---ISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSR 315
               +   VKQG    S T   VT  K    + +       SS + S S G   N T + 
Sbjct: 374 QPKVSTPVVKQGPVSQSATQQPVTADKQQGHEPVSPRSLQRSSSQRSPSPG--PNHTSNS 431

Query: 316 SIASEVIARPASLS 329
           S AS     P + S
Sbjct: 432 SNASNATVVPQNSS 445


>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
          Length = 1564

 Score = 37.7 bits (86), Expect = 0.035
 Identities = 75/371 (20%), Positives = 135/371 (36%), Gaps = 41/371 (11%)

Query: 16   QRAQSAFKEQRRQKLKEHLLR-----RKTLFAYKQENEMLSSRDQRVVTSEDQVQEGTKV 70
            QR Q+   E  R + ++ +       R+T      EN+  +   ++ +  + +   G + 
Sbjct: 920  QREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIER 979

Query: 71   LKLKTKMADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLL 130
              ++T   D +    P + +    + K     K  +++++      + K K   +TP + 
Sbjct: 980  GNIETTSEDGQVFS-PKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKK-KRGPRTPPIT 1037

Query: 131  LTEDDPQSQHMTLSQAFHLKN----NSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSK 186
              E+        L +  + KN    +S+KK+ T      D ++P +  +         + 
Sbjct: 1038 TKEE--------LVEMCNGKNGILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTATATT 1089

Query: 187  INSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTS 246
              S   PL             +AT   AT      T++    S  +S +T +T    T +
Sbjct: 1090 PGSTPSPLSSLLPPPPPVATATATTVPATLAA---TTAAAATSFSTSAITISTSATPTNT 1146

Query: 247  QNTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQG 306
             N         SH    R  V++     + +VTI    H K + Q        K SSS G
Sbjct: 1147 TNNTFANED--SHRKCHRTRVEKV---ETPHVTIEDAQHRKPMDQ--------KRSSSLG 1193

Query: 307  IIRNKTLSRSIASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEER 366
                   +RS  S    R  S SND      +    R+        D    +  E + ER
Sbjct: 1194 S------NRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGER 1247

Query: 367  KARLSEWKAGK 377
            K+R+ + K G+
Sbjct: 1248 KSRIDQLKRGE 1258


>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical
            region 1 [Homo sapiens]
          Length = 1400

 Score = 37.0 bits (84), Expect = 0.060
 Identities = 28/117 (23%), Positives = 50/117 (42%), Gaps = 9/117 (7%)

Query: 197  KDESSAATKKLSATIPK--------ATKPQPVNTSSVTVKSNRSSNMTAT-TKFVSTTSQ 247
            K  +   T  +SAT+PK        +T     NT+S T+ +   +  T+T T   +T   
Sbjct: 1121 KTPTDTTTASVSATVPKNNTLSVITSTPSTAPNTASKTMTTASKTTTTSTITSLPTTVFT 1180

Query: 248  NTQLVRPPIRSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSS 304
             T  +        ++T D+    IS  ++  T+   P       ++T  +SV T++S
Sbjct: 1181 TTSKITAGSEIPTASTTDSATTAISTKASGTTVESAPSTAPPTPAETTTASVPTTTS 1237


>gi|11225260 DNA topoisomerase I [Homo sapiens]
          Length = 765

 Score = 36.6 bits (83), Expect = 0.079
 Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 1/81 (1%)

Query: 119 KPKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSY 178
           K KD  ++ H      D + +H    +  H K+ S +K     K +      ++ V  S 
Sbjct: 40  KEKDREKSKHSNSEHKDSEKKHKEKEKTKH-KDGSSEKHKDKHKDRDKEKRKEEKVRASG 98

Query: 179 RGQIVQSKINSFRKPLQVKDE 199
             +I + K N F  P Q+KDE
Sbjct: 99  DAKIKKEKENGFSSPPQIKDE 119


>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
          Length = 3664

 Score = 36.6 bits (83), Expect = 0.079
 Identities = 105/575 (18%), Positives = 217/575 (37%), Gaps = 72/575 (12%)

Query: 79   DKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTEDDPQS 138
            D+++ +RP E   + V  +   P  P    + +  +     P DS +   L     D   
Sbjct: 714  DRDHERRPIERSQSPVHLRR--PQSPGASPSQAERL-----PSDSER--RLYSRSSDRSG 764

Query: 139  QHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSKINSFRKPLQVKD 198
               +LS   + K +  + +  T+ +K D      P       + V+ +    RK    KD
Sbjct: 765  SCSSLSPPRYEKLDKSRLERYTKNEKTDKERTFDP-------ERVERERRLIRKEKVEKD 817

Query: 199  ESSAATKKLSATIP--KATKPQPVNTSSVTVKSNRSSNMTATTKFVSTTSQNTQLVRPPI 256
            ++    +K     P  ++++    N    + +  RS N  +  K         +L   P 
Sbjct: 818  KTDKQKRKGKVHSPSSQSSETDQENEREQSPEKPRSCNKLSREKADKEGIAKNRLELMPC 877

Query: 257  RSHHSNTRDTVKQGISRTSANVTIRKGPHEKELLQSKTALSSVKTSSSQGIIRNKTLSRS 316
                  TR   K+G       V   K   + + ++S      ++ S ++    + +   S
Sbjct: 878  VVL---TRVKEKEGKVIDHTPVEKLKAKLDNDTVKSSALDQKLQVSQTEPAKSDLSKLES 934

Query: 317  IASEVIARPASLSNDKLMEKSEPVDQRRHTAGKAIVDSRSAQPKETSEERKARLSEWKAG 376
            +  +V       S+ +++EK   +  R+H   +   D  SA   E  E RK R ++    
Sbjct: 935  VRMKVPKEKGLSSHVEVVEKEGRLKARKHLKPEQPADGVSAVDLEKLEARKRRFAD---- 990

Query: 377  KGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDEQRLFTEKVNNTFSECLNLINEG 436
                     N    + +P  +   P         E ++ R+ ++K  +  S  + L+ EG
Sbjct: 991  --------SNLKAEKQKPEVKKSSP---------EMEDARVLSKKQPDVSSREVILLREG 1033

Query: 437  CPKEDILVTLNDLIKNIPDAKKLVKYWICLALIEPITSPIENIIAIYEKAILAGAQPIEE 496
              + +      +++K   ++KK     I L  +  + SP ++   +   ++ +G++P  +
Sbjct: 1034 --EAERKPVRKEILKR--ESKK-----IKLDRLNTVASP-KDCQELASISVGSGSRPSSD 1083

Query: 497  MRHTIVDILTMKSQEKANLGENMEKSCASKEEVKEVSIEDTGVDVDPEKLEMESKLHRNL 556
            ++  + +   +  +   N     +K   SK ++K++ + D   D  PE+      + +N 
Sbjct: 1084 LQARLGE---LAGESVENQEVQSKKPIPSKPQLKQLQVLD---DQGPER----EDVRKNY 1133

Query: 557  LFQDCEKEQDNKTKDPTHDVKTPNTETRTSCLIKYNVSTTPYLQSVKKKVQFDGTNSAFK 616
                 E  +    ++ +H V   NTE +    I +  S    ++  ++K Q +      K
Sbjct: 1134 CSLRDETPERKSGQEKSHSV---NTEEKIGIDIDHTQSYRKQMEQSRRKQQME--MEIAK 1188

Query: 617  ELKFLTPVR-----RSRRLQEKTSKLPDMLKDHYP 646
              KF +P +       R L  +  K P  + D  P
Sbjct: 1189 SEKFGSPKKDVDEYERRSLVHEVGKPPQDVTDDSP 1223


>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
           homolog 2 [Homo sapiens]
          Length = 1210

 Score = 36.6 bits (83), Expect = 0.079
 Identities = 66/300 (22%), Positives = 115/300 (38%), Gaps = 32/300 (10%)

Query: 120 PKDSNQTPHLLLTEDDPQSQHMTLSQAFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYR 179
           PK S++ P        P++ H            S  +Q   ++Q      PKKPV  S R
Sbjct: 564 PKSSSKAPRA-----PPEAPHPGKRSC----QKSPAQQEPPQRQTVGTKQPKKPVKASAR 614

Query: 180 G---QIVQSKINSFRKPLQVKDESSAATKKLSAT-IPKA---TKPQPVNTSSVTVKSNRS 232
                 +Q +      P   +D++S    K+     P+A    +P+P    S   K ++S
Sbjct: 615 AGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKS 674

Query: 233 SNMTATTKFVSTTSQNTQLVRPPIRSHHSNTRDTVKQGI------SRTSA---NVTIRKG 283
           S + A +K +S        V      H +    T  QG       SRTS     V +++ 
Sbjct: 675 S-LPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQED 733

Query: 284 PHEKEL---LQSKTALSSVK-TSSSQGIIRNKTLSRSIASEVIARPASLSNDKLMEKSEP 339
             +  L   L+    LS ++ T   Q ++   TL   + S +   P   S  +  E  +P
Sbjct: 734 SRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITL--DLLSRIPQPPGKGSRQRKAEDKQP 791

Query: 340 VDQRRHTAGKAIVDSRSAQPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNE 399
              ++H++ K   DS S   K+   E +      K    + +K   +S  + H+ + + +
Sbjct: 792 PAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTK 851


>gi|150456436 hypothetical protein LOC55719 isoform 1 [Homo sapiens]
          Length = 1173

 Score = 36.6 bits (83), Expect = 0.079
 Identities = 50/227 (22%), Positives = 95/227 (41%), Gaps = 30/227 (13%)

Query: 19  QSAFKEQRRQKLKEHLLR--RKTLFAYKQENEMLSSRDQRVVTSEDQVQEGTKVLKLKTK 76
           Q+ F E+R++   +  L+  R+++    +E+ +    D        Q ++  K + LKT 
Sbjct: 329 QNKFPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPD-----GPHQKEKFIKHIALKTP 383

Query: 77  ---MADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTE 133
              +  ++  K P++  + +  G     L PSN   +       H  ++S+Q       E
Sbjct: 384 GDVLRLEDISKEPSDETDGSSAG-----LAPSNSGNSGH-----HSTRNSDQIQVAGTKE 433

Query: 134 DDPQSQHMTLSQ-------AFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSK 186
              Q  H+ LSQ       A +L+ N      T EK+ +   + + P  GS    +V   
Sbjct: 434 TKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVPSAGS---SLVPLN 490

Query: 187 INSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSS 233
             +   P+  KD+  +++K+ S    ++TK +     +    SN SS
Sbjct: 491 AKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSS 537


>gi|209915547 hypothetical protein LOC55719 isoform 2 [Homo sapiens]
          Length = 1186

 Score = 36.6 bits (83), Expect = 0.079
 Identities = 50/227 (22%), Positives = 95/227 (41%), Gaps = 30/227 (13%)

Query: 19  QSAFKEQRRQKLKEHLLR--RKTLFAYKQENEMLSSRDQRVVTSEDQVQEGTKVLKLKTK 76
           Q+ F E+R++   +  L+  R+++    +E+ +    D        Q ++  K + LKT 
Sbjct: 329 QNKFPEKRKRNSVDSDLKSTRESMIPKARESFLEKRPD-----GPHQKEKFIKHIALKTP 383

Query: 77  ---MADKENMKRPAESKNNTVVGKHCIPLKPSNELTNSTVVIDTHKPKDSNQTPHLLLTE 133
              +  ++  K P++  + +  G     L PSN   +       H  ++S+Q       E
Sbjct: 384 GDVLRLEDISKEPSDETDGSSAG-----LAPSNSGNSGH-----HSTRNSDQIQVAGTKE 433

Query: 134 DDPQSQHMTLSQ-------AFHLKNNSKKKQMTTEKQKQDANMPKKPVLGSYRGQIVQSK 186
              Q  H+ LSQ       A +L+ N      T EK+ +   + + P  GS    +V   
Sbjct: 434 TKMQKPHLPLSQEKSAIKKASNLQKNKTASSTTKEKETKLPLLSRVPSAGS---SLVPLN 490

Query: 187 INSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSS 233
             +   P+  KD+  +++K+ S    ++TK +     +    SN SS
Sbjct: 491 AKNCALPVSKKDKERSSSKECSGHSTESTKHKEHKAKTNKADSNVSS 537


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.124    0.341 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,077,034
Number of Sequences: 37866
Number of extensions: 1123247
Number of successful extensions: 4593
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 212
Number of HSP's that attempted gapping in prelim test: 4310
Number of HSP's gapped (non-prelim): 498
length of query: 682
length of database: 18,247,518
effective HSP length: 109
effective length of query: 573
effective length of database: 14,120,124
effective search space: 8090831052
effective search space used: 8090831052
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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