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Search of human proteins with 148664213
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148664213 leucine rich repeat containing 43 isoform 1 [Homo
sapiens]
(656 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148664213 leucine rich repeat containing 43 isoform 1 [Homo s... 1298 0.0
gi|148664188 leucine rich repeat containing 43 isoform 2 [Homo s... 932 0.0
gi|55743114 leucine rich repeat containing 49 [Homo sapiens] 50 5e-06
gi|66472382 nischarin [Homo sapiens] 50 9e-06
gi|157674358 leucine rich repeat containing 50 [Homo sapiens] 47 7e-05
gi|226342935 podocan-like 1 isoform 3 [Homo sapiens] 46 9e-05
gi|226342933 podocan-like 1 isoform 2 [Homo sapiens] 46 9e-05
gi|226342931 podocan-like 1 isoform 1 [Homo sapiens] 46 9e-05
gi|153791330 leucine rich repeat neuronal 1 [Homo sapiens] 46 9e-05
gi|31621309 leucine rich repeat containing 6 [Homo sapiens] 46 1e-04
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof... 45 2e-04
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof... 45 2e-04
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 45 2e-04
gi|239752518 PREDICTED: similar to leucine rich repeat containin... 44 5e-04
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 44 5e-04
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 44 5e-04
gi|4758460 glycoprotein V (platelet) [Homo sapiens] 43 8e-04
gi|122937309 leucine rich repeat containing 4B [Homo sapiens] 43 8e-04
gi|41350214 asporin [Homo sapiens] 43 0.001
gi|95113664 leucine rich repeat containing 1 [Homo sapiens] 43 0.001
gi|157694513 leucine-rich repeat-containing G protein-coupled re... 42 0.001
gi|191252816 extracellular leucine-rich repeat and fibronectin t... 42 0.002
gi|110825984 malignant fibrous histiocytoma amplified sequence 1... 42 0.002
gi|21389431 leucine rich repeat containing 39 [Homo sapiens] 42 0.002
gi|21389483 leucine-rich repeats and guanylate kinase domain con... 42 0.002
gi|239754500 PREDICTED: Leucine-rich repeat-containing protein E... 41 0.003
gi|239749060 PREDICTED: Leucine-rich repeat-containing protein E... 41 0.003
gi|239743086 PREDICTED: Leucine-rich repeat-containing protein E... 41 0.003
gi|239508737 PREDICTED: Leucine-rich repeat-containing protein E... 41 0.003
gi|61742786 leucine rich repeat and death domain containing prot... 41 0.004
>gi|148664213 leucine rich repeat containing 43 isoform 1 [Homo
sapiens]
Length = 656
Score = 1298 bits (3360), Expect = 0.0
Identities = 656/656 (100%), Positives = 656/656 (100%)
Query: 1 MEASYESESESESEAGPGTQRPGTGTVSAAVREHLRKLCLREFPCGAGSWNKSRFLPQTW 60
MEASYESESESESEAGPGTQRPGTGTVSAAVREHLRKLCLREFPCGAGSWNKSRFLPQTW
Sbjct: 1 MEASYESESESESEAGPGTQRPGTGTVSAAVREHLRKLCLREFPCGAGSWNKSRFLPQTW 60
Query: 61 RTWRELVPREEDVVSPGEETVEALLGLVRSRHSPWALLNNSNAEDSFLRELAIRNPLTIT 120
RTWRELVPREEDVVSPGEETVEALLGLVRSRHSPWALLNNSNAEDSFLRELAIRNPLTIT
Sbjct: 61 RTWRELVPREEDVVSPGEETVEALLGLVRSRHSPWALLNNSNAEDSFLRELAIRNPLTIT 120
Query: 121 DTFFYSYFRSLRVIDKKVTLVDKDLLKFLKLEELVLSANRIKEVDATNLPPTLKVLELYG 180
DTFFYSYFRSLRVIDKKVTLVDKDLLKFLKLEELVLSANRIKEVDATNLPPTLKVLELYG
Sbjct: 121 DTFFYSYFRSLRVIDKKVTLVDKDLLKFLKLEELVLSANRIKEVDATNLPPTLKVLELYG 180
Query: 181 NEISSMECLCAHPPAGLQHLGLGHNKLLGPLESLYVTANHWPNLVSLDLGFNDLTDLQSM 240
NEISSMECLCAHPPAGLQHLGLGHNKLLGPLESLYVTANHWPNLVSLDLGFNDLTDLQSM
Sbjct: 181 NEISSMECLCAHPPAGLQHLGLGHNKLLGPLESLYVTANHWPNLVSLDLGFNDLTDLQSM 240
Query: 241 VTSLRTLRHLRLLVLQGNPLALVPYYRGLTIDSLAQLCVLDDITVSPNEKHLFRGLSLNG 300
VTSLRTLRHLRLLVLQGNPLALVPYYRGLTIDSLAQLCVLDDITVSPNEKHLFRGLSLNG
Sbjct: 241 VTSLRTLRHLRLLVLQGNPLALVPYYRGLTIDSLAQLCVLDDITVSPNEKHLFRGLSLNG 300
Query: 301 DLLAQEAQFVVTIGNIRGVLDTSVLDPEPRPEGPFITYNYYVTYDFVKDEEGEMNESAGV 360
DLLAQEAQFVVTIGNIRGVLDTSVLDPEPRPEGPFITYNYYVTYDFVKDEEGEMNESAGV
Sbjct: 301 DLLAQEAQFVVTIGNIRGVLDTSVLDPEPRPEGPFITYNYYVTYDFVKDEEGEMNESAGV 360
Query: 361 LAEIVKPSPSLELLVEESPEEVVEDVIEDIVEEVTEEVEGSLESEVEESGESELSVISGP 420
LAEIVKPSPSLELLVEESPEEVVEDVIEDIVEEVTEEVEGSLESEVEESGESELSVISGP
Sbjct: 361 LAEIVKPSPSLELLVEESPEEVVEDVIEDIVEEVTEEVEGSLESEVEESGESELSVISGP 420
Query: 421 STILQMPRASAEELAKLRLRIDPRLCPSPGTVLFSTAHKPWAEVIPCSYEMQHSLRDLVP 480
STILQMPRASAEELAKLRLRIDPRLCPSPGTVLFSTAHKPWAEVIPCSYEMQHSLRDLVP
Sbjct: 421 STILQMPRASAEELAKLRLRIDPRLCPSPGTVLFSTAHKPWAEVIPCSYEMQHSLRDLVP 480
Query: 481 LKAFLLAGTTVTIVEEKILSWPVVLPAVDSPLSAKKGKGEKDKKGKEKDRTGKGEKEPAK 540
LKAFLLAGTTVTIVEEKILSWPVVLPAVDSPLSAKKGKGEKDKKGKEKDRTGKGEKEPAK
Sbjct: 481 LKAFLLAGTTVTIVEEKILSWPVVLPAVDSPLSAKKGKGEKDKKGKEKDRTGKGEKEPAK 540
Query: 541 EWKVLKKKKEPPKELRQDPPILQVLGRGLVILEPLLAGEPLVSTVCNFGVVRTLTSDRLT 600
EWKVLKKKKEPPKELRQDPPILQVLGRGLVILEPLLAGEPLVSTVCNFGVVRTLTSDRLT
Sbjct: 541 EWKVLKKKKEPPKELRQDPPILQVLGRGLVILEPLLAGEPLVSTVCNFGVVRTLTSDRLT 600
Query: 601 LARDSKKIKKVAKKEKPKAVIPIYEGDYHPEPLTVEVQIQLNQCRSAEEALRMFAV 656
LARDSKKIKKVAKKEKPKAVIPIYEGDYHPEPLTVEVQIQLNQCRSAEEALRMFAV
Sbjct: 601 LARDSKKIKKVAKKEKPKAVIPIYEGDYHPEPLTVEVQIQLNQCRSAEEALRMFAV 656
>gi|148664188 leucine rich repeat containing 43 isoform 2 [Homo
sapiens]
Length = 471
Score = 932 bits (2410), Expect = 0.0
Identities = 471/471 (100%), Positives = 471/471 (100%)
Query: 186 MECLCAHPPAGLQHLGLGHNKLLGPLESLYVTANHWPNLVSLDLGFNDLTDLQSMVTSLR 245
MECLCAHPPAGLQHLGLGHNKLLGPLESLYVTANHWPNLVSLDLGFNDLTDLQSMVTSLR
Sbjct: 1 MECLCAHPPAGLQHLGLGHNKLLGPLESLYVTANHWPNLVSLDLGFNDLTDLQSMVTSLR 60
Query: 246 TLRHLRLLVLQGNPLALVPYYRGLTIDSLAQLCVLDDITVSPNEKHLFRGLSLNGDLLAQ 305
TLRHLRLLVLQGNPLALVPYYRGLTIDSLAQLCVLDDITVSPNEKHLFRGLSLNGDLLAQ
Sbjct: 61 TLRHLRLLVLQGNPLALVPYYRGLTIDSLAQLCVLDDITVSPNEKHLFRGLSLNGDLLAQ 120
Query: 306 EAQFVVTIGNIRGVLDTSVLDPEPRPEGPFITYNYYVTYDFVKDEEGEMNESAGVLAEIV 365
EAQFVVTIGNIRGVLDTSVLDPEPRPEGPFITYNYYVTYDFVKDEEGEMNESAGVLAEIV
Sbjct: 121 EAQFVVTIGNIRGVLDTSVLDPEPRPEGPFITYNYYVTYDFVKDEEGEMNESAGVLAEIV 180
Query: 366 KPSPSLELLVEESPEEVVEDVIEDIVEEVTEEVEGSLESEVEESGESELSVISGPSTILQ 425
KPSPSLELLVEESPEEVVEDVIEDIVEEVTEEVEGSLESEVEESGESELSVISGPSTILQ
Sbjct: 181 KPSPSLELLVEESPEEVVEDVIEDIVEEVTEEVEGSLESEVEESGESELSVISGPSTILQ 240
Query: 426 MPRASAEELAKLRLRIDPRLCPSPGTVLFSTAHKPWAEVIPCSYEMQHSLRDLVPLKAFL 485
MPRASAEELAKLRLRIDPRLCPSPGTVLFSTAHKPWAEVIPCSYEMQHSLRDLVPLKAFL
Sbjct: 241 MPRASAEELAKLRLRIDPRLCPSPGTVLFSTAHKPWAEVIPCSYEMQHSLRDLVPLKAFL 300
Query: 486 LAGTTVTIVEEKILSWPVVLPAVDSPLSAKKGKGEKDKKGKEKDRTGKGEKEPAKEWKVL 545
LAGTTVTIVEEKILSWPVVLPAVDSPLSAKKGKGEKDKKGKEKDRTGKGEKEPAKEWKVL
Sbjct: 301 LAGTTVTIVEEKILSWPVVLPAVDSPLSAKKGKGEKDKKGKEKDRTGKGEKEPAKEWKVL 360
Query: 546 KKKKEPPKELRQDPPILQVLGRGLVILEPLLAGEPLVSTVCNFGVVRTLTSDRLTLARDS 605
KKKKEPPKELRQDPPILQVLGRGLVILEPLLAGEPLVSTVCNFGVVRTLTSDRLTLARDS
Sbjct: 361 KKKKEPPKELRQDPPILQVLGRGLVILEPLLAGEPLVSTVCNFGVVRTLTSDRLTLARDS 420
Query: 606 KKIKKVAKKEKPKAVIPIYEGDYHPEPLTVEVQIQLNQCRSAEEALRMFAV 656
KKIKKVAKKEKPKAVIPIYEGDYHPEPLTVEVQIQLNQCRSAEEALRMFAV
Sbjct: 421 KKIKKVAKKEKPKAVIPIYEGDYHPEPLTVEVQIQLNQCRSAEEALRMFAV 471
>gi|55743114 leucine rich repeat containing 49 [Homo sapiens]
Length = 686
Score = 50.4 bits (119), Expect = 5e-06
Identities = 45/157 (28%), Positives = 73/157 (46%), Gaps = 16/157 (10%)
Query: 151 LEELVLSANRIKEVDATNLPPTLKVLELYGNEISSME---CLCAHPPAGLQHLGLGHNKL 207
L L+L NRIK++ +L VL+L+GN+I+ +E LC L L H
Sbjct: 158 LRVLLLGKNRIKKISNLENLKSLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDN 217
Query: 208 LGPLESL--------YVT----ANHWPNLVSLDLGFNDLTDLQSMVTSLRTLRHLRLLVL 255
L L+SL +T ++ P L L L FN+++ S V+ L L +
Sbjct: 218 LNGLDSLTELNLRHNQITFVRDVDNLPCLQHLFLSFNNISSFDS-VSCLADSSSLSDITF 276
Query: 256 QGNPLALVPYYRGLTIDSLAQLCVLDDITVSPNEKHL 292
GNP+A +Y+ + ++ QL LD ++ E+ +
Sbjct: 277 DGNPIAQESWYKHTVLQNMMQLRQLDMKRITEEERRM 313
>gi|66472382 nischarin [Homo sapiens]
Length = 1504
Score = 49.7 bits (117), Expect = 9e-06
Identities = 79/316 (25%), Positives = 134/316 (42%), Gaps = 35/316 (11%)
Query: 130 SLRVIDKKVTLVDKDLLKFLKLEELVLSANRIKEVDATNLPPTLKVLELYGNEISSMECL 189
+L + ++ +D+ + K+E L LS N + VD L L+L N++SS+E L
Sbjct: 291 TLDLSHNSISEIDESVKLIPKIEFLDLSHNGLLVVDNLQHLYNLVHLDLSYNKLSSLEGL 350
Query: 190 CAHPPAG-LQHLGLGHNKL--LGPLESLYVTANHWPNLVSLDLGFNDLTDLQSM--VTSL 244
H G ++ L L N L L L LY +LV+LDL N + ++ + + SL
Sbjct: 351 --HTKLGNIKTLNLAGNLLESLSGLHKLY-------SLVNLDLRDNRIEQMEEVRSIGSL 401
Query: 245 RTLRHLRLLVLQGNPLALVPYYRGLTI----DSLAQLCVLDDITVSPNEKHLFRGLSLNG 300
L H+ LL NPL+++P YR + + +++C+ D +T EK L L
Sbjct: 402 PCLEHVSLL---NNPLSIIPDYRTKVLAQFGERASEVCLDDTVT---TEKELDTVEVLKA 455
Query: 301 DLLAQEAQFVVTIGNIRGVLDTSVLDP---EPRPEGPFITYNYYVTYDFVKDEEGEMNES 357
A+E + ++ +G D+ + P P + + +G M
Sbjct: 456 IQKAKEVKSKLSNPEKKGGEDSRLSAAPCIRPSSSPPTVAPASASLPQPILSNQGIMFVQ 515
Query: 358 AGVLAEIVKPSPSLELLVEESP-EEVVEDVIEDI-----VEEVTEEVEGSLESEVEESGE 411
LA + + S L E P + D +E I + +V G++ E E
Sbjct: 516 EEALASSLSSTDS--LTPEHQPIAQGCSDSLESIPAGQAASDDLRDVPGAVGGASPEHAE 573
Query: 412 SELSVISGPSTILQMP 427
E+ V+ G I+ +P
Sbjct: 574 PEVQVVPGSGQIIFLP 589
Score = 35.8 bits (81), Expect = 0.13
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 6/80 (7%)
Query: 173 LKVLELYGNEISSMECLCAHPPAGLQHLGLGHNKLLGPLESLYVTANHWPNLVSLDLGFN 232
L L+L N IS ++ P ++ L L HN LL + H NLV LDL +N
Sbjct: 289 LTTLDLSHNSISEIDESVKLIPK-IEFLDLSHNGLL-----VVDNLQHLYNLVHLDLSYN 342
Query: 233 DLTDLQSMVTSLRTLRHLRL 252
L+ L+ + T L ++ L L
Sbjct: 343 KLSSLEGLHTKLGNIKTLNL 362
>gi|157674358 leucine rich repeat containing 50 [Homo sapiens]
Length = 725
Score = 46.6 bits (109), Expect = 7e-05
Identities = 46/163 (28%), Positives = 72/163 (44%), Gaps = 30/163 (18%)
Query: 131 LRVIDKKVTLVDK--DLLKFLKLEELVLSANRIKEVDATNLPPTLKVLELYGNEISSMEC 188
LR + ++ L+ K +L KL+ L LS N IK ++ + P L L++ N + ++E
Sbjct: 153 LRCLFLQMNLLRKIENLEPLQKLDALNLSNNYIKTIENLSCLPVLNTLQMAHNHLETVE- 211
Query: 189 LCAHPPAGLQHLGLGHNKLLGPLESLYVTANHWPNLVSLDLGFNDLTDLQSMVTSLRTLR 248
+QHL L LDL N L+D +++ L ++
Sbjct: 212 -------DIQHL------------------QECLRLCVLDLSHNKLSD-PEILSILESMP 245
Query: 249 HLRLLVLQGNP-LALVPYYRGLTIDSLAQLCVLDDITVSPNEK 290
LR+L L GNP + +P YR L L LDD V P ++
Sbjct: 246 DLRVLNLMGNPVIRQIPNYRRTVTVRLKHLTYLDDRPVFPKDR 288
>gi|226342935 podocan-like 1 isoform 3 [Homo sapiens]
Length = 421
Score = 46.2 bits (108), Expect = 9e-05
Identities = 49/162 (30%), Positives = 63/162 (38%), Gaps = 45/162 (27%)
Query: 147 KFLKLEELVLSANRIKEVDATNLPPTLKVLELYGNEISSMECLCAHPPAGLQHLGLGHNK 206
K LE L LS N++ V A LP TL +L L N I +E H GL++L L HN+
Sbjct: 173 KLHSLEYLDLSHNQLTTVPA-GLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQ 231
Query: 207 L---------LGPLESLY------------------------VTANH-----------WP 222
L L PL L+ + NH P
Sbjct: 232 LGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATP 291
Query: 223 NLVSLDLGFNDLTDLQSMVTSLRTLRHLRLLVLQGNPLALVP 264
L L+L +N L + + R LR LR L L GN L +P
Sbjct: 292 GLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLP 333
>gi|226342933 podocan-like 1 isoform 2 [Homo sapiens]
Length = 510
Score = 46.2 bits (108), Expect = 9e-05
Identities = 49/162 (30%), Positives = 63/162 (38%), Gaps = 45/162 (27%)
Query: 147 KFLKLEELVLSANRIKEVDATNLPPTLKVLELYGNEISSMECLCAHPPAGLQHLGLGHNK 206
K LE L LS N++ V A LP TL +L L N I +E H GL++L L HN+
Sbjct: 262 KLHSLEYLDLSHNQLTTVPA-GLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQ 320
Query: 207 L---------LGPLESLY------------------------VTANH-----------WP 222
L L PL L+ + NH P
Sbjct: 321 LGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATP 380
Query: 223 NLVSLDLGFNDLTDLQSMVTSLRTLRHLRLLVLQGNPLALVP 264
L L+L +N L + + R LR LR L L GN L +P
Sbjct: 381 GLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLP 422
Score = 31.2 bits (69), Expect = 3.2
Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 4/98 (4%)
Query: 154 LVLSANRIKEVDATNLPPTLKVLELYGNEISSMECLCAHPPAGLQHLGLGHNKLL-GPLE 212
L LS N++ + + LPP+L+ L L N IS + L+ L L HN+L L+
Sbjct: 198 LSLSNNQLSYLPPS-LPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLD 256
Query: 213 SLYVTANHWPNLVSLDLGFNDLTDLQSMVTSLRTLRHL 250
+ + H +L LDL N LT + + + + HL
Sbjct: 257 ATTFSKLH--SLEYLDLSHNQLTTVPAGLPRTLAILHL 292
>gi|226342931 podocan-like 1 isoform 1 [Homo sapiens]
Length = 512
Score = 46.2 bits (108), Expect = 9e-05
Identities = 49/162 (30%), Positives = 63/162 (38%), Gaps = 45/162 (27%)
Query: 147 KFLKLEELVLSANRIKEVDATNLPPTLKVLELYGNEISSMECLCAHPPAGLQHLGLGHNK 206
K LE L LS N++ V A LP TL +L L N I +E H GL++L L HN+
Sbjct: 264 KLHSLEYLDLSHNQLTTVPA-GLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQ 322
Query: 207 L---------LGPLESLY------------------------VTANH-----------WP 222
L L PL L+ + NH P
Sbjct: 323 LGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATP 382
Query: 223 NLVSLDLGFNDLTDLQSMVTSLRTLRHLRLLVLQGNPLALVP 264
L L+L +N L + + R LR LR L L GN L +P
Sbjct: 383 GLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLP 424
Score = 31.2 bits (69), Expect = 3.2
Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 4/98 (4%)
Query: 154 LVLSANRIKEVDATNLPPTLKVLELYGNEISSMECLCAHPPAGLQHLGLGHNKLL-GPLE 212
L LS N++ + + LPP+L+ L L N IS + L+ L L HN+L L+
Sbjct: 200 LSLSNNQLSYLPPS-LPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLD 258
Query: 213 SLYVTANHWPNLVSLDLGFNDLTDLQSMVTSLRTLRHL 250
+ + H +L LDL N LT + + + + HL
Sbjct: 259 ATTFSKLH--SLEYLDLSHNQLTTVPAGLPRTLAILHL 294
>gi|153791330 leucine rich repeat neuronal 1 [Homo sapiens]
Length = 716
Score = 46.2 bits (108), Expect = 9e-05
Identities = 50/163 (30%), Positives = 71/163 (43%), Gaps = 27/163 (16%)
Query: 144 DLLKFLKLEELVLSANR---IKEVDATNLPPTLKVLELYGNEISSMECLCAHPPAGLQHL 200
+L + L EL S N IKEV NL L L L N+I+ M C + LQ L
Sbjct: 90 ELQQLFNLTELDFSQNNFTNIKEVGLANLTQ-LTTLHLEENQITEMTDYCLQDLSNLQEL 148
Query: 201 GLGHNKL----------LGPLESLYVTAN-------HW----PNLVSLDLGFNDLTDLQS 239
+ HN++ L L L++ +N W PNL L +G N + +
Sbjct: 149 YINHNQISTISAHAFAGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILD 208
Query: 240 MVTSLRTLRHLRLLVLQGNPLALVPYYRGLTIDSLAQLCVLDD 282
M + + L +LR LVL G L +P + +DSL L D+
Sbjct: 209 M--NFKPLANLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDN 249
>gi|31621309 leucine rich repeat containing 6 [Homo sapiens]
Length = 466
Score = 45.8 bits (107), Expect = 1e-04
Identities = 42/141 (29%), Positives = 65/141 (46%), Gaps = 9/141 (6%)
Query: 151 LEELVLSANRIKEVDATNL-PPTLKVLELYGNEISSMECLCAHPPAGLQHLGLGHNKLLG 209
LEEL L I+ ++ + LK+L L N I +E + +L L + + +
Sbjct: 23 LEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIGKIENVSKLKKLEYLNLALNNIEKIE 82
Query: 210 PLESLYVTANHWPNLVSLDLGFNDLTDLQSMVTSLRTLRHLRLLVLQGNPLALVPYYRGL 269
LE L LDL N + +L S + +L+ HL+ L L GNP A +YR
Sbjct: 83 NLEGC-------EELAKLDLTVNFIGELSS-IKNLQHNIHLKELFLMGNPCASFDHYREF 134
Query: 270 TIDSLAQLCVLDDITVSPNEK 290
+ +L QL LD + P+E+
Sbjct: 135 VVATLPQLKWLDGKEIEPSER 155
>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform 1
[Homo sapiens]
Length = 1722
Score = 45.1 bits (105), Expect = 2e-04
Identities = 38/140 (27%), Positives = 64/140 (45%), Gaps = 5/140 (3%)
Query: 151 LEELVLSANRIKEVDATNLPPTLKVLELYGNEISSMECLCAHPPAGLQHLGLGHNKLLGP 210
L+ L L N + E+ + L+ L L N IS++E ++ LQ++ + N L
Sbjct: 1015 LQILKLQGNYLSELPSLENLVLLRELHLDDNSISTVEAFSSYWLPLLQNITISQNSL--- 1071
Query: 211 LESLYVTANHWPNLVSLDLGFNDLTDLQSMVTSLRTLRHLRLLVLQGNPLALVPYYRGLT 270
+ V H+ +L LD+ N L+DL+S + L L L GNPL +R
Sbjct: 1072 --TKIVPLFHFVSLEKLDVSHNCLSDLKSAIKWFDACYSLHELSLTGNPLLQETNWRDSL 1129
Query: 271 IDSLAQLCVLDDITVSPNEK 290
+ L L +L+ ++ N +
Sbjct: 1130 LKVLPALRILNGNILNSNSE 1149
>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform 2
[Homo sapiens]
Length = 1336
Score = 45.1 bits (105), Expect = 2e-04
Identities = 38/140 (27%), Positives = 64/140 (45%), Gaps = 5/140 (3%)
Query: 151 LEELVLSANRIKEVDATNLPPTLKVLELYGNEISSMECLCAHPPAGLQHLGLGHNKLLGP 210
L+ L L N + E+ + L+ L L N IS++E ++ LQ++ + N L
Sbjct: 1015 LQILKLQGNYLSELPSLENLVLLRELHLDDNSISTVEAFSSYWLPLLQNITISQNSL--- 1071
Query: 211 LESLYVTANHWPNLVSLDLGFNDLTDLQSMVTSLRTLRHLRLLVLQGNPLALVPYYRGLT 270
+ V H+ +L LD+ N L+DL+S + L L L GNPL +R
Sbjct: 1072 --TKIVPLFHFVSLEKLDVSHNCLSDLKSAIKWFDACYSLHELSLTGNPLLQETNWRDSL 1129
Query: 271 IDSLAQLCVLDDITVSPNEK 290
+ L L +L+ ++ N +
Sbjct: 1130 LKVLPALRILNGNILNSNSE 1149
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 45.1 bits (105), Expect = 2e-04
Identities = 45/149 (30%), Positives = 75/149 (50%), Gaps = 8/149 (5%)
Query: 143 KDLLKFLKLEELVLSANRIKEVDATNLPPTLKVLELYGNEISSMECLCAHPPAGLQHLGL 202
++L K +KLE L LS N I +++ + L+ L L N+IS +E + LQ L L
Sbjct: 119 ENLEKCVKLEVLNLSYNLIGKIEKLDKLLKLRELNLSYNKISKIEGI--ENMCNLQKLNL 176
Query: 203 GHNKLLGPLESLYV-TANHWPNLVSLDLGFNDLTDLQSMVTSLRTLRHLRLLVLQGNPLA 261
N+ +E + V +L L+L N ++ LQ ++ L+ L+ L L+L NP+
Sbjct: 177 AGNE----IEHIPVWLGKKLKSLRVLNLKGNKISSLQD-ISKLKPLQDLISLILVENPVV 231
Query: 262 LVPYYRGLTIDSLAQLCVLDDITVSPNEK 290
+P+Y TI L L L+ V+ ++
Sbjct: 232 TLPHYLQFTIFHLRSLESLEGQPVTTQDR 260
>gi|239752518 PREDICTED: similar to leucine rich repeat containing
50, partial [Homo sapiens]
Length = 489
Score = 43.9 bits (102), Expect = 5e-04
Identities = 38/142 (26%), Positives = 68/142 (47%), Gaps = 8/142 (5%)
Query: 151 LEELVLSANRIKEVDATNLPPTLKVLELYGNEISSMECLCAHPPAGLQHLGLGHNKLLGP 210
L+ L L N+I +++ N L+VL L N +S ++ L + L L L HN++
Sbjct: 5 LDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNL--NGLDSLTELNLRHNQI--- 59
Query: 211 LESLYVTANHWPNLVSLDLGFNDLTDLQSMVTSLRTLRHLRLLVLQGNPLALVPYYRGLT 270
+ ++ P L L L FN+++ S V+ L L + GNP+A +Y+
Sbjct: 60 --TFVRDVDNLPCLQHLFLSFNNISSFDS-VSCLADSSSLSDITFDGNPIAQESWYKHTV 116
Query: 271 IDSLAQLCVLDDITVSPNEKHL 292
+ ++ QL LD ++ E+ +
Sbjct: 117 LQNMMQLRQLDMKRITEEERRM 138
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 43.9 bits (102), Expect = 5e-04
Identities = 60/219 (27%), Positives = 92/219 (42%), Gaps = 49/219 (22%)
Query: 350 EEGEMNES-AGVLAEIVKPSPSLELLVEESPEEVV--EDVIEDIVEEVTEEVEGSL-ESE 405
EEGE E AE + E VEE EEV E+++ D E E+ + + +S
Sbjct: 562 EEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSP 621
Query: 406 VEESGESELSVISGPSTILQMPRASAEELAKLRLRIDPRLCPSPGTVLFSTAHKPWAEVI 465
VEE G+S + P++ EE K P P + + P +
Sbjct: 622 VEEKGKSPV------------PKSPVEEKGK---------SPVPKSPVEEKGKSP----V 656
Query: 466 PCSYEMQHSLRDLVPLKAFLLAGTTVTIVEEKILSWPVVLPAVDSPLSAKKGKGEKDKKG 525
P S P++ + + + VEEK S P SP+ K K E K G
Sbjct: 657 PKS-----------PVEEKGKSPVSKSPVEEKAKS-----PVPKSPVEEAKSKAEVGK-G 699
Query: 526 KEKDRTGKGEKEPAKEWKVLKKKKEP---PKELRQDPPI 561
++K+ K KE KE KV KK+++P P++ + + P+
Sbjct: 700 EQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPV 738
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 43.9 bits (102), Expect = 5e-04
Identities = 60/219 (27%), Positives = 92/219 (42%), Gaps = 49/219 (22%)
Query: 350 EEGEMNES-AGVLAEIVKPSPSLELLVEESPEEVV--EDVIEDIVEEVTEEVEGSL-ESE 405
EEGE E AE + E VEE EEV E+++ D E E+ + + +S
Sbjct: 186 EEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSP 245
Query: 406 VEESGESELSVISGPSTILQMPRASAEELAKLRLRIDPRLCPSPGTVLFSTAHKPWAEVI 465
VEE G+S + P++ EE K P P + + P +
Sbjct: 246 VEEKGKSPV------------PKSPVEEKGK---------SPVPKSPVEEKGKSP----V 280
Query: 466 PCSYEMQHSLRDLVPLKAFLLAGTTVTIVEEKILSWPVVLPAVDSPLSAKKGKGEKDKKG 525
P S P++ + + + VEEK S P SP+ K K E K G
Sbjct: 281 PKS-----------PVEEKGKSPVSKSPVEEKAKS-----PVPKSPVEEAKSKAEVGK-G 323
Query: 526 KEKDRTGKGEKEPAKEWKVLKKKKEP---PKELRQDPPI 561
++K+ K KE KE KV KK+++P P++ + + P+
Sbjct: 324 EQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPV 362
>gi|4758460 glycoprotein V (platelet) [Homo sapiens]
Length = 560
Score = 43.1 bits (100), Expect = 8e-04
Identities = 53/177 (29%), Positives = 78/177 (44%), Gaps = 34/177 (19%)
Query: 112 AIRNPLTITDTFFYSYFRSLRVIDKKVTLVDKDLLKFLKLEELVLSANRIKEVDA---TN 168
A+ + + + + F + +LR ID+ + K + L+EL L+ N++ + A TN
Sbjct: 116 ALLDKMVLLEQLFLDH-NALRGIDQNM------FQKLVNLQELALNQNQLDFLPASLFTN 168
Query: 169 LPPTLKVLELYGNEISSMECLCAHPPAGLQHLGLGHNKL----------LGPLESLYVTA 218
L LK+L+L GN ++ + A L+ L L N+L LG L L
Sbjct: 169 LE-NLKLLDLSGNNLTHLPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHR 227
Query: 219 NH-----------WPNLVSLDLGFNDLTDLQSMVTSLRTLRHLRLLVLQGNPLALVP 264
NH PNL SL L N L L S + +L LL L NPLA +P
Sbjct: 228 NHIRSIAPGAFDRLPNLSSLTLSRNHLAFLPSAL--FLHSHNLTLLTLFENPLAELP 282
Score = 32.3 bits (72), Expect = 1.4
Identities = 34/116 (29%), Positives = 51/116 (43%), Gaps = 7/116 (6%)
Query: 151 LEELVLSANRIKEVDATNLPPT--LKVLELYGNEISSMECLCAHPPAGLQHLGLGHNKLL 208
L+ L++S + I V LK L L N+I+ + L+ L L HN L
Sbjct: 76 LQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQLFLDHNALR 135
Query: 209 GPLESLYVTANHWPNLVSLDLGFNDLTDLQSMVTSLRTLRHLRLLVLQGNPLALVP 264
G ++++ NL L L N L L + + L +L+LL L GN L +P
Sbjct: 136 GIDQNMF---QKLVNLQELALNQNQLDFLPASL--FTNLENLKLLDLSGNNLTHLP 186
>gi|122937309 leucine rich repeat containing 4B [Homo sapiens]
Length = 713
Score = 43.1 bits (100), Expect = 8e-04
Identities = 51/169 (30%), Positives = 79/169 (46%), Gaps = 31/169 (18%)
Query: 129 RSLRVIDKKVTLVDKDLLKFLK-LEELVLSANRIK--EVDATNLPPTLKVLELYGNEISS 185
R L + + + ++ D K L+ LE L LS N ++ EV A N P+L LEL+ N +++
Sbjct: 89 RYLNLQENGIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTT 148
Query: 186 MECLCAHPPAGLQHLGLGHNKLLGPLESLYVTA-NHWPNLVSLDLG------------FN 232
+ + L+ L L +N P+ES+ A N P+L LDLG F
Sbjct: 149 VPTQAFEYLSKLRELWLRNN----PIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFE 204
Query: 233 DLTDLQSM---------VTSLRTLRHLRLLVLQGNPLALV--PYYRGLT 270
L +L+ + + +L L L L L GN L L+ ++GLT
Sbjct: 205 GLVNLRYLNLGMCNLKDIPNLTALVRLEELELSGNRLDLIRPGSFQGLT 253
>gi|41350214 asporin [Homo sapiens]
Length = 380
Score = 42.7 bits (99), Expect = 0.001
Identities = 49/162 (30%), Positives = 71/162 (43%), Gaps = 39/162 (24%)
Query: 131 LRVIDKKVTLVDKDLLKFLK-LEELVLSAN--------------------RIKEVDATN- 168
LR+ + KV + KD K + L L +SAN RI E T+
Sbjct: 176 LRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVTVFHIRIAEAKLTSV 235
Query: 169 ---LPPTLKVLELYGNEISSMECLCAHPPAGLQHLGLGHNKLL----GPLESLYVTANHW 221
LPPTL L L N+IS++E LQ LGLG+NK+ G L ++
Sbjct: 236 PKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANI------- 288
Query: 222 PNLVSLDLGFNDLTDLQSMVTSLRTLRHLRLLVLQGNPLALV 263
P + + L N L + S L L++L+++ L N +A V
Sbjct: 289 PRVREIHLENNKLKKIPS---GLPELKYLQIIFLHSNSIARV 327
>gi|95113664 leucine rich repeat containing 1 [Homo sapiens]
Length = 524
Score = 42.7 bits (99), Expect = 0.001
Identities = 48/173 (27%), Positives = 79/173 (45%), Gaps = 28/173 (16%)
Query: 129 RSLRVIDKKVTLVDKDLLKFLKLEELVLSANRIKEV-DATNLPPTLKVLELYGN------ 181
R L + D ++ + ++ F++L EL +S N I E+ ++ + L+V + GN
Sbjct: 62 RKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIPEIPESISFCKALQVADFSGNPLTRLP 121
Query: 182 ----EISSMECLCAHPPAGLQHL--GLGHNKLLGPLESLYVTANHWPN-------LVSLD 228
E+ ++ CL + LQ L +G+ L LE + P+ L LD
Sbjct: 122 ESFPELQNLTCLSVND-ISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELD 180
Query: 229 LGFNDLTDLQSMVTSLRTLRHLRLLVLQGNPLALVPYYRGLTIDSLAQLCVLD 281
LG N++ +L S+ L HL+ L L GN L+ +P I +L L LD
Sbjct: 181 LGNNEIYNLPE---SIGALLHLKDLWLDGNQLSELPQ----EIGNLKNLLCLD 226
Score = 35.8 bits (81), Expect = 0.13
Identities = 63/232 (27%), Positives = 104/232 (44%), Gaps = 60/232 (25%)
Query: 129 RSLRVIDKK---VTLVDKDLLKFLK-LEELVLSANRIKEV------------------DA 166
R + IDK+ + V +++ ++ + LEEL+L AN+++E+ +
Sbjct: 12 RHVESIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEI 71
Query: 167 TNLPP------TLKVLELYGNEISSMECLCAHPPAGLQHLGLGHNKLLGPLESLYVTANH 220
LPP L L++ NEI + + A LQ N L ES
Sbjct: 72 QRLPPEIANFMQLVELDVSRNEIPEIPESISFCKA-LQVADFSGNPLTRLPES------- 123
Query: 221 WPNLVSLD-LGFNDLTDLQSMVTSLRTLRHLRLLVLQGNPLALVPYYRGLTIDSLAQLCV 279
+P L +L L ND++ LQS+ ++ L +L L L+ N L +P DSL QL
Sbjct: 124 FPELQNLTCLSVNDIS-LQSLPENIGNLYNLASLELRENLLTYLP-------DSLTQLRR 175
Query: 280 LDDITVSPNE-----------KHLFRGLSLNGDLLAQEAQFVVTIGNIRGVL 320
L+++ + NE HL + L L+G+ L++ Q IGN++ +L
Sbjct: 176 LEELDLGNNEIYNLPESIGALLHL-KDLWLDGNQLSELPQ---EIGNLKNLL 223
>gi|157694513 leucine-rich repeat-containing G protein-coupled
receptor 4 [Homo sapiens]
Length = 951
Score = 42.4 bits (98), Expect = 0.001
Identities = 41/142 (28%), Positives = 69/142 (48%), Gaps = 9/142 (6%)
Query: 126 SYFRSLRVIDKKVTLVDKDLLKFL-KLEELVLSANRIKEVDATNLP--PTLKVLELYGNE 182
S +SLR+ +T V +D + L +L L L N + EV L PTL+ L L N+
Sbjct: 129 SALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNK 188
Query: 183 ISSMECLCAHPPAGLQHLGLGHNKLLGPLESLYVTANHWPNLVSLDLGFNDLTDLQSMVT 242
ISS+ + L L L +NK+ + + + NL +LDL +N+L + +
Sbjct: 189 ISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCF---DGLDNLETLDLNYNNLGEFPQAIK 245
Query: 243 SLRTLRHLRLLVLQGNPLALVP 264
+L +L+ L N ++++P
Sbjct: 246 ALPSLKELG---FHSNSISVIP 264
>gi|191252816 extracellular leucine-rich repeat and fibronectin type
III domain containing 1 [Homo sapiens]
Length = 828
Score = 42.0 bits (97), Expect = 0.002
Identities = 43/130 (33%), Positives = 57/130 (43%), Gaps = 25/130 (19%)
Query: 153 ELVLSANRIKEVDATNLPP--TLKVLELYGNEISSMECLCAHPPAGLQHLGLGHNKL--- 207
+L L+ NRI+ V +L L L L NEI +E LQ L LG+N+L
Sbjct: 64 DLRLNENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNL 123
Query: 208 -------LGPLESLYVTAN---------HW--PNLVSLDLGFNDLTDLQSMVTSLRTLRH 249
LG LE LY+ AN W PN+V++DL N + L S + L
Sbjct: 124 TEGMLRGLGKLEYLYLQANLIEVVMASSFWECPNIVNIDLSMNRIQQLNS--GTFAGLAK 181
Query: 250 LRLLVLQGNP 259
L + L NP
Sbjct: 182 LSVCELYSNP 191
>gi|110825984 malignant fibrous histiocytoma amplified sequence 1
[Homo sapiens]
Length = 1052
Score = 42.0 bits (97), Expect = 0.002
Identities = 50/184 (27%), Positives = 80/184 (43%), Gaps = 43/184 (23%)
Query: 126 SYFRSLRVIDKKVTLVDKDLLKFLKLEELVLSANRIKEV-DATNLPPTLKVLELYGNEIS 184
S R+L V ++T + LL+ + LEEL +S+NR++ + + + LK+L L G E+
Sbjct: 181 SRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRALKILWLSGAELG 240
Query: 185 SMEC-LCAHPPAGLQHLGLGHNKL--------------------------------LGPL 211
++ C A L+ L L +N L L L
Sbjct: 241 TLPAGFC--ELASLESLMLDNNGLQALPAQFSCLQRLKMLNLSSNLFEEFPAALLPLAGL 298
Query: 212 ESLYVTANHWPNLVSLDLGFNDLTDL-------QSMVTSLRTLRHLRLLVLQGNPLALVP 264
E LY++ N ++ SL G L L + + S+ L L LVLQGN +A++P
Sbjct: 299 EELYLSRNQLTSVPSLISGLGRLLTLWLDNNRIRYLPDSIVELTGLEELVLQGNQIAVLP 358
Query: 265 YYRG 268
+ G
Sbjct: 359 DHFG 362
Score = 35.4 bits (80), Expect = 0.17
Identities = 44/148 (29%), Positives = 59/148 (39%), Gaps = 19/148 (12%)
Query: 151 LEELVLSANRIKEVD--ATNLPPTLKVLELYGNEISSMECLCAHPPAGLQHLGLGHNKLL 208
L LVL NR + L L L++ N ++++ L+ L L HN+L
Sbjct: 89 LRVLVLRRNRFARLPPAVAELGHHLTELDVSHNRLTALGAEVVSALRELRKLNLSHNQLP 148
Query: 209 GPLESLYVTANHWPNLVSLDLGFNDLTDLQSMVTSLRTLRHLRLLVLQGNPLALVPYYRG 268
L A+ L LD+ FN L L SL L LR L + N L P
Sbjct: 149 ALPAQLGALAH----LEELDVSFNRLAHLPD---SLSCLSRLRTLDVDHNQLTAFP---- 197
Query: 269 LTIDSLAQLCVLDDITVSPNEKHLFRGL 296
L QL L+++ VS N RGL
Sbjct: 198 ---RQLLQLVALEELDVSSNR---LRGL 219
>gi|21389431 leucine rich repeat containing 39 [Homo sapiens]
Length = 335
Score = 41.6 bits (96), Expect = 0.002
Identities = 51/206 (24%), Positives = 90/206 (43%), Gaps = 36/206 (17%)
Query: 87 LVRSRHSPWALLNNSNAEDSFLRELAIRNPLTITDTFFYSYFRSLRVID---KKVTLVDK 143
+++ W L +S + + L+E + + F F++L V+D ++ +
Sbjct: 64 ILKIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFIGRFQNLIVLDLSRNTISEIPP 123
Query: 144 DLLKFLKLEELVLSANRIKEV-------------------DATNLPPTLK------VLEL 178
+ +L+EL+LS N+IK V D +LP L L+L
Sbjct: 124 GIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQELSNLLKLTHLDL 183
Query: 179 YGNEISSMECLCAHPPAGLQHLGLGHNKLLGPLESLYVTANHWPNLVSLDLGFNDLTDLQ 238
N+ +++ + PA L+ L +G NK LE L T NL +L L N++T L
Sbjct: 184 SMNDFTTIPLAVLNMPA-LEWLDMGSNK----LEQLPDTIERMQNLHTLWLQRNEITCLP 238
Query: 239 SMVTSLRTLRHLRLLVLQGNPLALVP 264
+++ +++L LVL N L +P
Sbjct: 239 QTISN---MKNLGTLVLSNNKLQDIP 261
>gi|21389483 leucine-rich repeats and guanylate kinase domain
containing [Homo sapiens]
Length = 825
Score = 41.6 bits (96), Expect = 0.002
Identities = 73/307 (23%), Positives = 123/307 (40%), Gaps = 42/307 (13%)
Query: 18 GTQRPGTGTVSAAVREHLRKLCLREFPCGAGSWNKSRFLPQTWRTWRELVPREEDVVSPG 77
G R TG S R + FP G + S ++L+ R +++ S G
Sbjct: 19 GLGRSRTGARSLQFRAEKERQPCWSFPMGQKTKGSSNIASSY--LLQQLMHRYQELDSDG 76
Query: 78 EETV-EALLGLVRSRHSPWALLNNSNAEDSFLRELAIRNPL-------TITDTFFYSYFR 129
+E E G S S +LN D LRE A+ L + T+ +
Sbjct: 77 DEDQGEGEAGSEESSESE--MLNLEEEFDGVLREEAVAKALHHLGRSGSGTEQVY----- 129
Query: 130 SLRVIDKKVTLVDKDLL-KFLKLEELVLSANRIKEVDATNLPPTLKVLELYGNEISSMEC 188
L + L+D +L ++ L++L LSAN+I+++ + P L LEL ++ +
Sbjct: 130 -LNLTLSGCNLIDVSILCGYVHLQKLDLSANKIEDLSCVSCMPYL--LELNASQNNLTTF 186
Query: 189 LCAHPPAGLQHLGLGHNKL--------LGPLESLYVTANHWPNLVSLDLGFN--DLTDLQ 238
PP L+ HN++ L L + N + L++ N L+
Sbjct: 187 FNFKPPKNLKKADFSHNQISEICDLSAYHALTKLILDGNEIEEISGLEMCNNLIHLSLAN 246
Query: 239 SMVTSLRTLRHL--RLLVLQGNPLALVPYYRGLTIDSLAQLCVLDDITVSPNEKHLFRGL 296
+ +T++ L L ++L L N + + I L L L ++ +S N+ +GL
Sbjct: 247 NKITTINGLNKLPIKILCLSNNQIEM--------ITGLEDLKALQNLDLSHNQISSLQGL 298
Query: 297 SLNGDLL 303
N DLL
Sbjct: 299 E-NHDLL 304
Score = 38.1 bits (87), Expect = 0.026
Identities = 44/166 (26%), Positives = 69/166 (41%), Gaps = 25/166 (15%)
Query: 144 DLLKFLKLEELVLSANRIKEVDATNLPPTLKVLELYGNEISSMECLCAHP---------- 193
DL + L +L+L N I+E+ + L L L N+I+++ L P
Sbjct: 210 DLSAYHALTKLILDGNEIEEISGLEMCNNLIHLSLANNKITTINGLNKLPIKILCLSNNQ 269
Query: 194 ---------PAGLQHLGLGHNKLLGPLESLYVTANHWPNLVSLDLGFNDLTDLQSMVTSL 244
LQ+L L HN+ + SL NH L ++L N + +L+ + +
Sbjct: 270 IEMITGLEDLKALQNLDLSHNQ----ISSLQGLENH-DLLEVINLEDNKIAELRE-IEYI 323
Query: 245 RTLRHLRLLVLQGNPLALVPYYRGLTIDSLAQLCVLDDITVSPNEK 290
+ L LR+L L NP+ Y I L +L LD + EK
Sbjct: 324 KNLPILRVLNLLENPIQEKSEYWFFVIFMLLRLTELDQKKIKVEEK 369
>gi|239754500 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 41.2 bits (95), Expect = 0.003
Identities = 41/138 (29%), Positives = 67/138 (48%), Gaps = 7/138 (5%)
Query: 153 ELVLSANRIKEVDATNLPPTLKVLELYGNEISSMECLCAHPPAGLQHLGLGHNKLLGPLE 212
EL LS + EV + LK L L+ N++ + L + L L L +N + +E
Sbjct: 98 ELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRN--YCLTELYLNNNAIF-EIE 154
Query: 213 SLYVTANHWPNLVSLDLGFNDLTDLQSMVTSLRTLRHLRLLVLQGNPLALVPYYRGLTID 272
L+ + P+L L L N+LT++ + V L+ + +L++L L NPL YR I
Sbjct: 155 GLH----YLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYIIY 210
Query: 273 SLAQLCVLDDITVSPNEK 290
L + +LD V+ E+
Sbjct: 211 HLPGVELLDRNQVTEKER 228
Score = 33.5 bits (75), Expect = 0.64
Identities = 50/202 (24%), Positives = 83/202 (41%), Gaps = 17/202 (8%)
Query: 44 PCGAGSWNKSRFLPQTWRTWRELVPREEDVVSPGEETVEALLGLVRSRHSPWALLNNSNA 103
PC SW+ + +P+T R WR L E + VE L + R
Sbjct: 46 PCVLMSWDPNP-VPRTLRCWR-LRRASETALQSSRRAVEDQLKICGHRRDA--------- 94
Query: 104 EDSFLRELAIRNPLTITDTFFYSYFRSLRVIDKKVTLVDKDLLKFLKLEELVLSANRIKE 163
D F L+ + + D + + L + K+ + L + L EL L+ N I E
Sbjct: 95 -DVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITF-LTRNYCLTELYLNNNAIFE 152
Query: 164 VDATNLPPTLKVLELYGNEISSMECLCAHPPA--GLQHLGLGHNKLLG-PLESLYVTANH 220
++ + P+L +L L+ NE+++++ L+ L L N L L LY+ H
Sbjct: 153 IEGLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYI-IYH 211
Query: 221 WPNLVSLDLGFNDLTDLQSMVT 242
P + LD + +SM+T
Sbjct: 212 LPGVELLDRNQVTEKERRSMIT 233
>gi|239749060 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 41.2 bits (95), Expect = 0.003
Identities = 41/138 (29%), Positives = 67/138 (48%), Gaps = 7/138 (5%)
Query: 153 ELVLSANRIKEVDATNLPPTLKVLELYGNEISSMECLCAHPPAGLQHLGLGHNKLLGPLE 212
EL LS + EV + LK L L+ N++ + L + L L L +N + +E
Sbjct: 98 ELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRN--YCLTELYLNNNAIF-EIE 154
Query: 213 SLYVTANHWPNLVSLDLGFNDLTDLQSMVTSLRTLRHLRLLVLQGNPLALVPYYRGLTID 272
L+ + P+L L L N+LT++ + V L+ + +L++L L NPL YR I
Sbjct: 155 GLH----YLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYIIY 210
Query: 273 SLAQLCVLDDITVSPNEK 290
L + +LD V+ E+
Sbjct: 211 HLPGVELLDRNQVTEKER 228
Score = 33.5 bits (75), Expect = 0.64
Identities = 50/202 (24%), Positives = 83/202 (41%), Gaps = 17/202 (8%)
Query: 44 PCGAGSWNKSRFLPQTWRTWRELVPREEDVVSPGEETVEALLGLVRSRHSPWALLNNSNA 103
PC SW+ + +P+T R WR L E + VE L + R
Sbjct: 46 PCVLMSWDPNP-VPRTLRCWR-LRRASETALQSSRRAVEDQLKICGHRRDA--------- 94
Query: 104 EDSFLRELAIRNPLTITDTFFYSYFRSLRVIDKKVTLVDKDLLKFLKLEELVLSANRIKE 163
D F L+ + + D + + L + K+ + L + L EL L+ N I E
Sbjct: 95 -DVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITF-LTRNYCLTELYLNNNAIFE 152
Query: 164 VDATNLPPTLKVLELYGNEISSMECLCAHPPA--GLQHLGLGHNKLLG-PLESLYVTANH 220
++ + P+L +L L+ NE+++++ L+ L L N L L LY+ H
Sbjct: 153 IEGLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYI-IYH 211
Query: 221 WPNLVSLDLGFNDLTDLQSMVT 242
P + LD + +SM+T
Sbjct: 212 LPGVELLDRNQVTEKERRSMIT 233
>gi|239743086 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 41.2 bits (95), Expect = 0.003
Identities = 41/138 (29%), Positives = 67/138 (48%), Gaps = 7/138 (5%)
Query: 153 ELVLSANRIKEVDATNLPPTLKVLELYGNEISSMECLCAHPPAGLQHLGLGHNKLLGPLE 212
EL LS + EV + LK L L+ N++ + L + L L L +N + +E
Sbjct: 98 ELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRN--YCLTELYLNNNAIF-EIE 154
Query: 213 SLYVTANHWPNLVSLDLGFNDLTDLQSMVTSLRTLRHLRLLVLQGNPLALVPYYRGLTID 272
L+ + P+L L L N+LT++ + V L+ + +L++L L NPL YR I
Sbjct: 155 GLH----YLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYIIY 210
Query: 273 SLAQLCVLDDITVSPNEK 290
L + +LD V+ E+
Sbjct: 211 HLPGVELLDRNQVTEKER 228
Score = 33.5 bits (75), Expect = 0.64
Identities = 50/202 (24%), Positives = 83/202 (41%), Gaps = 17/202 (8%)
Query: 44 PCGAGSWNKSRFLPQTWRTWRELVPREEDVVSPGEETVEALLGLVRSRHSPWALLNNSNA 103
PC SW+ + +P+T R WR L E + VE L + R
Sbjct: 46 PCVLMSWDPNP-VPRTLRCWR-LRRASETALQSSRRAVEDQLKICGHRRDA--------- 94
Query: 104 EDSFLRELAIRNPLTITDTFFYSYFRSLRVIDKKVTLVDKDLLKFLKLEELVLSANRIKE 163
D F L+ + + D + + L + K+ + L + L EL L+ N I E
Sbjct: 95 -DVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITF-LTRNYCLTELYLNNNAIFE 152
Query: 164 VDATNLPPTLKVLELYGNEISSMECLCAHPPA--GLQHLGLGHNKLLG-PLESLYVTANH 220
++ + P+L +L L+ NE+++++ L+ L L N L L LY+ H
Sbjct: 153 IEGLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYI-IYH 211
Query: 221 WPNLVSLDLGFNDLTDLQSMVT 242
P + LD + +SM+T
Sbjct: 212 LPGVELLDRNQVTEKERRSMIT 233
>gi|239508737 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 41.2 bits (95), Expect = 0.003
Identities = 41/138 (29%), Positives = 67/138 (48%), Gaps = 7/138 (5%)
Query: 153 ELVLSANRIKEVDATNLPPTLKVLELYGNEISSMECLCAHPPAGLQHLGLGHNKLLGPLE 212
EL LS + EV + LK L L+ N++ + L + L L L +N + +E
Sbjct: 98 ELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRN--YCLTELYLNNNAIF-EIE 154
Query: 213 SLYVTANHWPNLVSLDLGFNDLTDLQSMVTSLRTLRHLRLLVLQGNPLALVPYYRGLTID 272
L+ + P+L L L N+LT++ + V L+ + +L++L L NPL YR I
Sbjct: 155 GLH----YLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYIIY 210
Query: 273 SLAQLCVLDDITVSPNEK 290
L + +LD V+ E+
Sbjct: 211 HLPGVELLDRNQVTEKER 228
Score = 33.5 bits (75), Expect = 0.64
Identities = 50/202 (24%), Positives = 83/202 (41%), Gaps = 17/202 (8%)
Query: 44 PCGAGSWNKSRFLPQTWRTWRELVPREEDVVSPGEETVEALLGLVRSRHSPWALLNNSNA 103
PC SW+ + +P+T R WR L E + VE L + R
Sbjct: 46 PCVLMSWDPNP-VPRTLRCWR-LRRASETALQSSRRAVEDQLKICGHRRDA--------- 94
Query: 104 EDSFLRELAIRNPLTITDTFFYSYFRSLRVIDKKVTLVDKDLLKFLKLEELVLSANRIKE 163
D F L+ + + D + + L + K+ + L + L EL L+ N I E
Sbjct: 95 -DVFELFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITF-LTRNYCLTELYLNNNAIFE 152
Query: 164 VDATNLPPTLKVLELYGNEISSMECLCAHPPA--GLQHLGLGHNKLLG-PLESLYVTANH 220
++ + P+L +L L+ NE+++++ L+ L L N L L LY+ H
Sbjct: 153 IEGLHYLPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYI-IYH 211
Query: 221 WPNLVSLDLGFNDLTDLQSMVT 242
P + LD + +SM+T
Sbjct: 212 LPGVELLDRNQVTEKERRSMIT 233
>gi|61742786 leucine rich repeat and death domain containing protein
isoform 3 [Homo sapiens]
Length = 893
Score = 40.8 bits (94), Expect = 0.004
Identities = 44/126 (34%), Positives = 60/126 (47%), Gaps = 19/126 (15%)
Query: 145 LLKFLKLEELVLSANRIKEV-DATNLPPTLKVLELYGNEISSMECLCAHPPA-----GLQ 198
+L+ L L+LS N + E+ +A P L L + N + ++ PPA LQ
Sbjct: 144 VLQMRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTL------PPALGALSTLQ 197
Query: 199 HLGLGHNKLLGPLESLYVTANHWPNLVSLDLGFNDLTDLQSMVTSLRTLRHLRLLVLQGN 258
L L N L ++L +L+ L+L N L QS+ SL LR LRLLVL N
Sbjct: 198 RLDLSQNLL----DTLPPEIGGLGSLLELNLASNRL---QSLPASLAGLRSLRLLVLHSN 250
Query: 259 PLALVP 264
LA VP
Sbjct: 251 LLASVP 256
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,880,554
Number of Sequences: 37866
Number of extensions: 1299732
Number of successful extensions: 5655
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 198
Number of HSP's that attempted gapping in prelim test: 5072
Number of HSP's gapped (non-prelim): 686
length of query: 656
length of database: 18,247,518
effective HSP length: 109
effective length of query: 547
effective length of database: 14,120,124
effective search space: 7723707828
effective search space used: 7723707828
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.