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Search of human proteins with 148539600
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148539600 ubiquitin specific protease 53 [Homo sapiens]
(1073 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148539600 ubiquitin specific protease 53 [Homo sapiens] 2210 0.0
gi|124001558 ubiquitin specific peptidase 54 [Homo sapiens] 521 e-147
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 49 3e-05
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 43 0.001
gi|60097902 filaggrin [Homo sapiens] 43 0.002
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] 42 0.004
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 41 0.005
gi|217330641 IWS1 homolog [Homo sapiens] 41 0.007
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 39 0.026
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 39 0.026
gi|148746183 ubiquitin specific protease 35 [Homo sapiens] 39 0.034
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 38 0.045
gi|28559039 mediator complex subunit 1 [Homo sapiens] 38 0.059
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 37 0.077
gi|161169017 neuron navigator 2 isoform 4 [Homo sapiens] 37 0.077
gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens] 37 0.077
gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens] 37 0.077
gi|239746654 PREDICTED: ubiquitin specific protease 41 [Homo sap... 37 0.100
gi|32313610 ubiquitin specific protease 18 [Homo sapiens] 37 0.100
gi|50962882 G patch domain containing 8 [Homo sapiens] 37 0.13
gi|239757637 PREDICTED: ubiquitin specific peptidase 41 [Homo sa... 36 0.17
gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens] 36 0.17
gi|87299628 biorientation of chromosomes in cell division 1-like... 36 0.17
gi|33620755 YEATS domain containing 2 [Homo sapiens] 36 0.17
gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens] 35 0.29
gi|169215723 PREDICTED: ubiquitin specific peptidase 41 [Homo sa... 35 0.29
gi|221316624 dystonin isoform 4 [Homo sapiens] 35 0.29
gi|221316622 dystonin isoform 3 [Homo sapiens] 35 0.29
gi|221316618 dystonin isoform 2 [Homo sapiens] 35 0.29
gi|34577047 dystonin isoform 1 [Homo sapiens] 35 0.29
>gi|148539600 ubiquitin specific protease 53 [Homo sapiens]
Length = 1073
Score = 2210 bits (5727), Expect = 0.0
Identities = 1073/1073 (100%), Positives = 1073/1073 (100%)
Query: 1 MAWVKFLRKPGGNLGKVYQPGSMLSLAPTKGLLNEPGQNSCFLNSAVQVLWQLDIFRRSL 60
MAWVKFLRKPGGNLGKVYQPGSMLSLAPTKGLLNEPGQNSCFLNSAVQVLWQLDIFRRSL
Sbjct: 1 MAWVKFLRKPGGNLGKVYQPGSMLSLAPTKGLLNEPGQNSCFLNSAVQVLWQLDIFRRSL 60
Query: 61 RVLTGHVCQGDACIFCALKTIFAQFQHSREKALPSDNIRHALAESFKDEQRFQLGLMDDA 120
RVLTGHVCQGDACIFCALKTIFAQFQHSREKALPSDNIRHALAESFKDEQRFQLGLMDDA
Sbjct: 61 RVLTGHVCQGDACIFCALKTIFAQFQHSREKALPSDNIRHALAESFKDEQRFQLGLMDDA 120
Query: 121 AECFENMLERIHFHIVPSRDADMCTSKSCITHQKFAMTLYEQCVCRSCGASSDPLPFTEF 180
AECFENMLERIHFHIVPSRDADMCTSKSCITHQKFAMTLYEQCVCRSCGASSDPLPFTEF
Sbjct: 121 AECFENMLERIHFHIVPSRDADMCTSKSCITHQKFAMTLYEQCVCRSCGASSDPLPFTEF 180
Query: 181 VRYISTTALCNEVERMLERHERFKPEMFAELLQAANTTDDYRKCPSNCGQKIKIRRVLMN 240
VRYISTTALCNEVERMLERHERFKPEMFAELLQAANTTDDYRKCPSNCGQKIKIRRVLMN
Sbjct: 181 VRYISTTALCNEVERMLERHERFKPEMFAELLQAANTTDDYRKCPSNCGQKIKIRRVLMN 240
Query: 241 CPEIVTIGLVWDSEHSDLTEAVVRNLATHLYLPGLFYRVTDENAKNSELNLVGMICYTSQ 300
CPEIVTIGLVWDSEHSDLTEAVVRNLATHLYLPGLFYRVTDENAKNSELNLVGMICYTSQ
Sbjct: 241 CPEIVTIGLVWDSEHSDLTEAVVRNLATHLYLPGLFYRVTDENAKNSELNLVGMICYTSQ 300
Query: 301 HYCAFAFHTKSSKWVFFDDANVKEIGTRWKDVVSKCIRCHFQPLLLFYANPDGTAVSTED 360
HYCAFAFHTKSSKWVFFDDANVKEIGTRWKDVVSKCIRCHFQPLLLFYANPDGTAVSTED
Sbjct: 301 HYCAFAFHTKSSKWVFFDDANVKEIGTRWKDVVSKCIRCHFQPLLLFYANPDGTAVSTED 360
Query: 361 ALRQVISWSHYKSVAENMGCEKPVIHKSDNLKENGFGDQAKQRENQKFPTDNISSSNRSH 420
ALRQVISWSHYKSVAENMGCEKPVIHKSDNLKENGFGDQAKQRENQKFPTDNISSSNRSH
Sbjct: 361 ALRQVISWSHYKSVAENMGCEKPVIHKSDNLKENGFGDQAKQRENQKFPTDNISSSNRSH 420
Query: 421 SHTGVGKGPAKLSHIDQREKIKDISRECALKAIEQKNLLSSQRKDLEKGQRKDLGRHRDL 480
SHTGVGKGPAKLSHIDQREKIKDISRECALKAIEQKNLLSSQRKDLEKGQRKDLGRHRDL
Sbjct: 421 SHTGVGKGPAKLSHIDQREKIKDISRECALKAIEQKNLLSSQRKDLEKGQRKDLGRHRDL 480
Query: 481 VDEDLSHFQSGSPPAPNGFKQHGNPHLYHSQGKGSYKHDRVVPQSRASAQIISSSKSQIL 540
VDEDLSHFQSGSPPAPNGFKQHGNPHLYHSQGKGSYKHDRVVPQSRASAQIISSSKSQIL
Sbjct: 481 VDEDLSHFQSGSPPAPNGFKQHGNPHLYHSQGKGSYKHDRVVPQSRASAQIISSSKSQIL 540
Query: 541 APGEKITGKVKSDNGTGYDTDSSQDSRDRGNSCDSSSKSRNRGWKPMRETLNVDSIFSES 600
APGEKITGKVKSDNGTGYDTDSSQDSRDRGNSCDSSSKSRNRGWKPMRETLNVDSIFSES
Sbjct: 541 APGEKITGKVKSDNGTGYDTDSSQDSRDRGNSCDSSSKSRNRGWKPMRETLNVDSIFSES 600
Query: 601 EKRQHSPRHKPNISNKPKSSKDPSFSNWPKENPKQKGLMTIYEDEMKQEIGSRSSLESNG 660
EKRQHSPRHKPNISNKPKSSKDPSFSNWPKENPKQKGLMTIYEDEMKQEIGSRSSLESNG
Sbjct: 601 EKRQHSPRHKPNISNKPKSSKDPSFSNWPKENPKQKGLMTIYEDEMKQEIGSRSSLESNG 660
Query: 661 KGAEKNKGLVEGKVHGDNWQMQRTESGYESSDHISNGSTNLDSPVIDGNGTVMDISGVKE 720
KGAEKNKGLVEGKVHGDNWQMQRTESGYESSDHISNGSTNLDSPVIDGNGTVMDISGVKE
Sbjct: 661 KGAEKNKGLVEGKVHGDNWQMQRTESGYESSDHISNGSTNLDSPVIDGNGTVMDISGVKE 720
Query: 721 TVCFSDQITTSNLNKERGDCTSLQSQHHLEGFRKELRNLEAGYKSHEFHPESHLQIKNHL 780
TVCFSDQITTSNLNKERGDCTSLQSQHHLEGFRKELRNLEAGYKSHEFHPESHLQIKNHL
Sbjct: 721 TVCFSDQITTSNLNKERGDCTSLQSQHHLEGFRKELRNLEAGYKSHEFHPESHLQIKNHL 780
Query: 781 IKRSHVHEDNGKLFPSSSLQIPKDHNAREHIHQSDEQKLEKPNECKFSEWLNIENSERTG 840
IKRSHVHEDNGKLFPSSSLQIPKDHNAREHIHQSDEQKLEKPNECKFSEWLNIENSERTG
Sbjct: 781 IKRSHVHEDNGKLFPSSSLQIPKDHNAREHIHQSDEQKLEKPNECKFSEWLNIENSERTG 840
Query: 841 LPFHVDNSASGKRVNSNEPSSLWSSHLRTVGLKPETAPLIQQQNIMDQCYFENSLSTECI 900
LPFHVDNSASGKRVNSNEPSSLWSSHLRTVGLKPETAPLIQQQNIMDQCYFENSLSTECI
Sbjct: 841 LPFHVDNSASGKRVNSNEPSSLWSSHLRTVGLKPETAPLIQQQNIMDQCYFENSLSTECI 900
Query: 901 IRSASRSDGCQMPKLFCQNLPPPLPPKKYAITSVPQSEKSESTPDVKLTEVFKATSHLPK 960
IRSASRSDGCQMPKLFCQNLPPPLPPKKYAITSVPQSEKSESTPDVKLTEVFKATSHLPK
Sbjct: 901 IRSASRSDGCQMPKLFCQNLPPPLPPKKYAITSVPQSEKSESTPDVKLTEVFKATSHLPK 960
Query: 961 HSLSTASEPSLEVSTHMNDERHKETFQVRECFGNTPNCPSSSSTNDFQANSGAIDAFCQP 1020
HSLSTASEPSLEVSTHMNDERHKETFQVRECFGNTPNCPSSSSTNDFQANSGAIDAFCQP
Sbjct: 961 HSLSTASEPSLEVSTHMNDERHKETFQVRECFGNTPNCPSSSSTNDFQANSGAIDAFCQP 1020
Query: 1021 ELDSISTCPNETVSLTTYFSVDSCMTDTYRLKYHQRPKLSFPESSGFCNNSLS 1073
ELDSISTCPNETVSLTTYFSVDSCMTDTYRLKYHQRPKLSFPESSGFCNNSLS
Sbjct: 1021 ELDSISTCPNETVSLTTYFSVDSCMTDTYRLKYHQRPKLSFPESSGFCNNSLS 1073
>gi|124001558 ubiquitin specific peptidase 54 [Homo sapiens]
Length = 1684
Score = 521 bits (1343), Expect = e-147
Identities = 313/743 (42%), Positives = 415/743 (55%), Gaps = 80/743 (10%)
Query: 1 MAWVKFLRKPG-GNLGKVYQPGSMLSLAPTKGLLNEPGQNSCFLNSAVQVLWQLDIFRRS 59
M+W + G G++ ++ P S S+AP+KGL NEPGQNSCFLNSA+QVLW LDIFRRS
Sbjct: 1 MSWKRNYFSGGRGSVQGMFAPRSSTSIAPSKGLSNEPGQNSCFLNSALQVLWHLDIFRRS 60
Query: 60 LRVLTGHVCQGDACIFCALKTIFAQFQHSREKALPSDNIRHALAESFKDEQRFQLGLMDD 119
R LT H C GD+CIFCALK IF QFQ S EK LPSD +R ALA++F+DEQRFQLG+MDD
Sbjct: 61 FRQLTTHKCMGDSCIFCALKGIFNQFQCSSEKVLPSDTLRSALAKTFQDEQRFQLGIMDD 120
Query: 120 AAECFENMLERIHFHIVPSRDADMCTSKSCITHQKFAMTLYEQCVCRSCGASSDPLPFTE 179
AAECFEN+L RIHFHI D+CT++ CI+HQKFAMTL+EQCVC SCGA+SDPLPF +
Sbjct: 121 AAECFENLLMRIHFHIADETKEDICTAQHCISHQKFAMTLFEQCVCTSCGATSDPLPFIQ 180
Query: 180 FVRYISTTALCNEVERMLERHERFKPEMFAELLQAANTTDDYRKCPSNCGQKIKIRRVLM 239
V YISTT+LCN+ MLER E+ P MF ELLQ A+T D R CPSNCG++I+IRRVLM
Sbjct: 181 MVHYISTTSLCNQAICMLERREKPSPSMFGELLQNASTMGDLRNCPSNCGERIRIRRVLM 240
Query: 240 NCPEIVTIGLVWDSEHSDLTEAVVRNLATHLYLPGLFYRVTDENAKNSELNLVGMICYTS 299
N P+I+TIGLVWDS+HSDL E V+ +L T L L LF+RVTD+ AK SEL LVGMICY
Sbjct: 241 NAPQIITIGLVWDSDHSDLAEDVIHSLGTCLKLGDLFFRVTDDRAKQSELYLVGMICYYG 300
Query: 300 QHYCAFAFHTKSSKWVFFDDANVKEIGTRWKDVVSKCIRCHFQPLLLFYANPDGTAVSTE 359
+HY F F TK KW++FDDA+VKEIG +WKDVV+KCI+ H+QPLLL YA+P GT VST+
Sbjct: 301 KHYSTFFFQTKIRKWMYFDDAHVKEIGPKWKDVVTKCIKGHYQPLLLLYADPQGTPVSTQ 360
Query: 360 DALRQVISWSHYKSVAENMGCEKPVIHKSDNLKENGFGDQAKQRENQKFPTDNISSSNRS 419
D Q S+ ++ ++ + SD ++ + + + + SS ++
Sbjct: 361 DLPPQAEFQSYSRTCYDSEDSGREPSISSDTRTDSSTESYPYKHSHHESVVSHFSSDSQG 420
Query: 420 HSHTGVGKGPAKLSHIDQREKIKDISRECALKAIEQKNLLSSQRKDLEKGQRKDLGRHRD 479
V S R+ EC K +K L +++ + +RK
Sbjct: 421 TVIYNVENDSMSQS---SRDTGHLTDSECNQKHTSKKGSLIERKRSSGRVRRK------- 470
Query: 480 LVDEDLSHFQSGSPPAPNGFKQHGNPHLYHSQGKGSYKHDRVVPQSRASAQIISSSKSQI 539
G P +G YHS+G+ + Q+ +A SSS +++
Sbjct: 471 -----------GDEPQASG---------YHSEGETLKE-----KQAPRNASKPSSSTNRL 505
Query: 540 LAPGEKITGKVKSDNGTGYDTDSSQDSRDRG---------------------NSCDSSSK 578
E ++ + + T+ R RG S S SK
Sbjct: 506 RDFKETVSNMIHNRPSLASQTNVGSHCRGRGGDQPDKKPPRTLPLHSRDWEIESTSSESK 565
Query: 579 SRNRG-----WKPMRETLNVDSIFSESEKRQHSPRHKPNISNKPKSSKDPSFSNWPKENP 633
S + W+P RE+LN+DSIFS+ +KR+H + S+D + P E
Sbjct: 566 SSSSSKYRPTWRPKRESLNIDSIFSK-DKRKHC-----GYTQLSPFSEDSAKEFIPDEPS 619
Query: 634 KQKGLMTIYEDEMKQEIGSRSSLESNGKGAEKNKGLVEGKVHGDNWQMQRTESGYESSDH 693
K + G S A L+E +QR ESGYESS+
Sbjct: 620 K--------PPSYDIKFGGPSPQYKRWGPARPGSHLLEQHPR----LIQRMESGYESSER 667
Query: 694 ISNGSTNLDSPVIDGNGTVMDIS 716
S+ +LD+ + + + D S
Sbjct: 668 NSSSPVSLDAALPESSNVYRDPS 690
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 48.9 bits (115), Expect = 3e-05
Identities = 95/478 (19%), Positives = 160/478 (33%), Gaps = 14/478 (2%)
Query: 386 HKSDNLKENGFGDQAKQRENQKFPTDNISSSNRSHSHTGVGKGPAKLSHIDQREKIKDIS 445
+ SD K+NG G +K E+ +D+ S +N S S+ G G D+ + K S
Sbjct: 493 YNSDESKDNGNGSDSKGAEDDD--SDSTSDTNNSDSN---GNGNNGNDDNDKSDSGKGKS 547
Query: 446 RECALKAIEQKNLLSSQRKDLEKGQRKDLGRHRDLVDEDLSHFQSGSPPAPNGFKQHGNP 505
+ + N SS D D D D S + + +
Sbjct: 548 DSSDSDSSDSSN--SSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSS 605
Query: 506 HLYHSQGKGSYKHDRVVPQSRASAQIISSSKSQILAPGEKITGKVKSDNGTGYDTDSSQD 565
S S D +S +S SS S + SDN D+ +S +
Sbjct: 606 DSSDSSDS-SDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSN 664
Query: 566 SRDRGNSCDSSSKSRNRGWKPMRETLNVDSIFSESEKRQHSPRHKPNISNKPKSSKDPSF 625
S D +S DSS S + ++ + + SE S + S+ SS S
Sbjct: 665 SSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNS- 723
Query: 626 SNWPKENPKQKGLMTIYEDEMKQEIGSRSSLESNGKGAEKNKGLVEGKVHGDNWQMQRTE 685
S+ N + D S SS S+ + + + D+ +
Sbjct: 724 SDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 783
Query: 686 SGYESSDHI-SNGSTNLDSPVIDGNGTVMDISGVKETVCFSDQITTSNLNKERGDCTSLQ 744
+SS+ S+ S+N + + S ++ SD +S+ + S
Sbjct: 784 DSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSD 843
Query: 745 SQHHLEGFRKELRNLEAGYKSHEFHPESHLQIKNHLIKRSHVHEDNGKLFPSSSLQIPKD 804
S +G + N S + S + S +E + SS D
Sbjct: 844 SSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNS-SDSSDSSNSSD 902
Query: 805 HNAREHIHQSDEQKLEKPNECKFSEWLN-IENSERTGLPFHVDNSASGKRVNSNEPSS 861
++ + + SD + N SE N +NS + D+S S NS++ S+
Sbjct: 903 SDSSDSSNSSDSS--DSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSN 958
Score = 40.8 bits (94), Expect = 0.007
Identities = 65/347 (18%), Positives = 112/347 (32%), Gaps = 7/347 (2%)
Query: 388 SDNLKENGFGDQAKQRENQKFPTDNISSSNRSHSHTGVGKGPAKLSHIDQREKIKDISRE 447
S N ++ + N +D+ SS+ S S + + + S S +
Sbjct: 820 SSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSS-NRSDSSNSSDSSDSSDSSNSSD 878
Query: 448 CALKAIEQKNLLSSQRKDLEKGQRKDLGRHRDLVDEDLSHFQSGSPPAPNGFKQHGNPHL 507
+ + ++ SS D D + D S S S + N +
Sbjct: 879 SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938
Query: 508 YHSQGKGSYKHDRVVPQSRASAQIISSSKSQILAPGEKITGKVKSDNGTGYDTDSSQDSR 567
+S S S+ +SS S + SD+ D+ S DS
Sbjct: 939 SNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSS 998
Query: 568 DRGNSCDSSSKSRNRGWKPMRETLNVDSIFSESEKRQHSPRHKPNISNKPKSSKDPSFSN 627
D NS DSS S + ++ N + S+ S + S+ S D S S+
Sbjct: 999 DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1058
Query: 628 WPKENPKQKGLMTIYEDEMKQEIGSRSSLESNGKGAEKNKGLVEGKVHGDNWQMQRTESG 687
++ D S SS S+ + + + D+ +
Sbjct: 1059 DSSDSSDSSD----SSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1114
Query: 688 YESSD--HISNGSTNLDSPVIDGNGTVMDISGVKETVCFSDQITTSN 732
+SSD + S+ S + DS + D S E+ SD +S+
Sbjct: 1115 SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSD 1161
Score = 38.5 bits (88), Expect = 0.034
Identities = 75/375 (20%), Positives = 120/375 (32%), Gaps = 23/375 (6%)
Query: 388 SDNLKENGFGDQAKQRENQKFPTDNISSSNRSHSHTGVGKGPAKLSHIDQREKIKDISRE 447
SDN + + + ++ + SSS+ S++ + S+ + D S
Sbjct: 651 SDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDS 710
Query: 448 CALKAIEQKNLLSSQRKDLEKGQRKDLGRHRDLVDED---LSHFQSGSPPAPNGFKQHGN 504
+ + + N SS D D D S S S + N +
Sbjct: 711 DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS 770
Query: 505 PHLYHSQGKGSYKHDRVVPQSRASAQIISSSKSQILAPGEKITGKVKSDNGTGYDTDSSQ 564
S + S S+ +SS S + + SD+ D+ +S
Sbjct: 771 SDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSS 830
Query: 565 DSRDRGN------SCDSS----SKSRNRGWKPMRETLNVDSIFSESEKRQHSPRHKPNIS 614
DS D N S DSS S S NR ++ N S+ S + S
Sbjct: 831 DSSDSSNSSDSSDSSDSSDGSDSDSSNRS-----DSSNSSDSSDSSDSSNSSDSSDSSDS 885
Query: 615 NKPKSSKDPSFSNWPKENPKQKGLMTIYEDEMKQEIGSRSSLESNGKGAEKNKGLVEGKV 674
N+ +S D S S+ ++ + D S SS SN +
Sbjct: 886 NESSNSSDSSDSSNSSDSDSSDSSNS--SDSSDSSNSSDSSESSNSSDNSNSSDSSNSSD 943
Query: 675 HGDNWQMQRTESGYESSDHISNGSTNLDSPVIDG--NGTVMDISGVKETVCFSDQITTSN 732
D+ + SSD SN S + DS D + D S ++ SD +SN
Sbjct: 944 SSDSSDSSNSSDSSNSSDS-SNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSN 1002
Query: 733 LNKERGDCTSLQSQH 747
+ S S +
Sbjct: 1003 SSDSSDSSDSSDSSN 1017
Score = 35.8 bits (81), Expect = 0.22
Identities = 43/221 (19%), Positives = 76/221 (34%), Gaps = 9/221 (4%)
Query: 533 SSSKSQILAPGEKITGKVKSDNGTGYDTDSSQDSRDRGNSCDSSSKSRNRGWKPMRETLN 592
SS S+ + SD+ D+ S DS D +S DSS+ S + ++ +
Sbjct: 1078 SSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1137
Query: 593 VDSIFSESEKRQHSPRHKPNISNKPKSSKDPSFSNWPKENPKQKGLMTIYEDEMKQEIGS 652
+ S+ + S + S+ S D S S+ ++ D S
Sbjct: 1138 SSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS-------SDSSDSSDSS 1190
Query: 653 RSSLESNGKGAEKNKGLVEGKVHGDNWQMQRTESGYESSD--HISNGSTNLDSPVIDGNG 710
SS S+ + + + D+ + +SSD S+ S + DS +
Sbjct: 1191 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSS 1250
Query: 711 TVMDISGVKETVCFSDQITTSNLNKERGDCTSLQSQHHLEG 751
D S ++ S+ + S G+ S EG
Sbjct: 1251 DSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEG 1291
Score = 35.4 bits (80), Expect = 0.29
Identities = 42/214 (19%), Positives = 73/214 (34%), Gaps = 14/214 (6%)
Query: 533 SSSKSQILAPGEKITGKVKSDNGTGYDTDSSQDSRDRGNSCDSSSKSRNRGWKPMRETLN 592
SS S + SD+ D+ S DS D +S DSS S + ++ +
Sbjct: 1075 SSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1134
Query: 593 VDSIFSESEKRQHSPRHKPNISNKPKSSKDPSFSNWPKENPKQKGLMTIYEDEMKQEIGS 652
+ S+ S + S+ S D S S+ ++ D S
Sbjct: 1135 SSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDS----------SDSSNSSDSS 1184
Query: 653 RSSLESNGKGAEKNKGLVEGKVHGDNWQMQRTESGYESSDHISNGSTNLDSPVIDGNGTV 712
SS S+ + + + D+ + +SSD + +N S D +
Sbjct: 1185 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSS--- 1241
Query: 713 MDISGVKETVCFSDQITTSNLNKERGDCTSLQSQ 746
D S + SD +S+ + D + QS+
Sbjct: 1242 -DSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSK 1274
Score = 33.1 bits (74), Expect = 1.4
Identities = 31/148 (20%), Positives = 55/148 (37%), Gaps = 6/148 (4%)
Query: 525 SRASAQIISSSKSQILAPGEKITGKVKSDNGTGYDTDSSQDSRDRGNSCDSSSKSRNRGW 584
S +S SS S + SD+ D+ S DS D +S DSS S +
Sbjct: 1148 SESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1207
Query: 585 KPMRETLNVDSIFSESEKRQHSPRHKPNISNKPKSSKDPSFSNWPKENPKQKGLMTIYED 644
++ + S+ S ++ + S+ S D S S+ ++ + D
Sbjct: 1208 SDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSND 1267
Query: 645 EMKQEIGS------RSSLESNGKGAEKN 666
E + S S +S+ +G++ N
Sbjct: 1268 ESDSQSKSGNGNNNGSDSDSDSEGSDSN 1295
Score = 33.1 bits (74), Expect = 1.4
Identities = 39/170 (22%), Positives = 59/170 (34%), Gaps = 18/170 (10%)
Query: 533 SSSKSQILAPGEKITGKVKSDNGTGYDTDSSQDSRDRGNSCDSSSKSRNRGWKPMRETLN 592
SS S + SD+ D+ +S DS D +S DSS S + ++ +
Sbjct: 1150 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1209
Query: 593 VDSIFSESEKRQHSPRHKPNISNKPKSSKDPSFSNWPKENPKQKGLMTIYEDEMKQEIGS 652
S+ S + SN+ S D S S+ D S
Sbjct: 1210 SSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSS----------------DSSNSSDSS 1253
Query: 653 RSSLESNGKGAEKNKGLVEGKVHGDNWQMQRTESGYESSDHISNGSTNLD 702
SS S+ ++ + K N ++S E SD SN ST+ D
Sbjct: 1254 DSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSD--SNHSTSDD 1301
Score = 30.4 bits (67), Expect = 9.4
Identities = 28/142 (19%), Positives = 47/142 (33%)
Query: 525 SRASAQIISSSKSQILAPGEKITGKVKSDNGTGYDTDSSQDSRDRGNSCDSSSKSRNRGW 584
S +S SS S + SD+ ++ S DS D +S DSS S +
Sbjct: 1145 SDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1204
Query: 585 KPMRETLNVDSIFSESEKRQHSPRHKPNISNKPKSSKDPSFSNWPKENPKQKGLMTIYED 644
++ + S+ S N S+ S D S S+ ++ D
Sbjct: 1205 SDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSD 1264
Query: 645 EMKQEIGSRSSLESNGKGAEKN 666
+ S N G++ +
Sbjct: 1265 SNDESDSQSKSGNGNNNGSDSD 1286
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 43.1 bits (100), Expect = 0.001
Identities = 37/156 (23%), Positives = 59/156 (37%), Gaps = 15/156 (9%)
Query: 493 PPAPNGFKQHGNPHLYHSQGKGSYKHDRVVPQSRASAQIISSSKSQILAPGEKITGKVKS 552
P P + NP+ + + GS++ + P A + S +S L G ++
Sbjct: 80 PTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGH---SSQRT 136
Query: 553 DNGTGYDTDSSQDSRDRGNSCDSSSKSRNRGWKPMRETLN---------VDSIFSESEKR 603
G+ T+SS DR + +S S SR +G + + S + S R
Sbjct: 137 SAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSR 196
Query: 604 QHSPRHKPNISNKPKSSKDPSFSNW--PKENPKQKG 637
H H + KS +DP +NW P P G
Sbjct: 197 SHGNDHHSKEHQRSKSPRDPD-ANWDSPSRVPFSSG 231
Score = 33.5 bits (75), Expect = 1.1
Identities = 34/134 (25%), Positives = 52/134 (38%), Gaps = 9/134 (6%)
Query: 494 PAPNGFKQHGNPHLYHSQGKGSYKHDRVVPQSRASAQIISSSKSQILAPGEKITGKVKSD 553
P+ G+K+ G QG G+ D P+ +SA SK+ I E G+ KS
Sbjct: 497 PSSQGYKKEGR-----EQGTGNSYTDTSGPKETSSATPGRDSKT-IQKGSESGRGRQKSP 550
Query: 554 NGTGYDTDSSQDSRDRGNSCDSSSKSRNRGWKPMRETLNVD---SIFSESEKRQHSPRHK 610
+ T + + + ++ RG + VD S+ S K K
Sbjct: 551 AQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRK 610
Query: 611 PNISNKPKSSKDPS 624
PNI + KSS P+
Sbjct: 611 PNIKKESKSSPRPT 624
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 42.7 bits (99), Expect = 0.002
Identities = 92/494 (18%), Positives = 175/494 (35%), Gaps = 60/494 (12%)
Query: 393 ENGFGDQAKQRENQKFPTDNISSSNRSHSHTGVGKGPAKLSHIDQREKIKDISRECALKA 452
++G ++Q N++ D S H G ++ S + Q E + +
Sbjct: 1534 QSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSS 1593
Query: 453 IEQKNLLSSQRKDLEKGQRKDLGRHRDLVDEDLSHFQSGSPPAPNGFKQHGNPHLYHSQG 512
+ Q +D E+ H E H HG H S
Sbjct: 1594 VSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHG--HSAESSR 1651
Query: 513 KGSYKHDRVVPQSRASAQIISSSKSQILAPGEKITGKVK------SDNGTGYDTDSS--Q 564
+ +H ++ + Q SS + +PGE+ + + +D+GTG DSS
Sbjct: 1652 QSGTRH----AETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVG 1707
Query: 565 DSRDRGNSCDSSSKSRNRGWKPMRETLNVDSIFSESEKRQHSPRHKPNISNK--PKSSKD 622
DS +RG+S +S S E + S+ + + H H+ + + +S +
Sbjct: 1708 DSGNRGSSGSQASDSEGHS-----EESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRS 1762
Query: 623 PSFSNWPKENPKQKGLMTIYEDEMKQEIGSRSSLESNGKGAEKNKGLVEGKVHGDNWQMQ 682
SF L + E + R+ + G+ +++ + H + + Q
Sbjct: 1763 GSF------------LYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQ 1810
Query: 683 RTESGYESSDHISNGSTNLDSPVIDGNG---------TVMDISGVKETVCFSDQITTSNL 733
T G+ S ++ + V D +G T + S V S ++
Sbjct: 1811 DTIRGHPGSSRGGRQGSHYEQSV-DSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTR 1869
Query: 734 N-KERGDCTSLQ-SQHHLEGFRKE-LRNLEAGYKSHEFHPESHLQIKNHLIKRSHVHEDN 790
N K+ GD + S+HH R + R+ + G S Q S V +D+
Sbjct: 1870 NEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQ-------GSSVSQDS 1922
Query: 791 GKLFPSSSLQIPKDHNAREHIHQSDEQKLE------KPNECKFSEWLNIENSERTGLPFH 844
S + +R H+ + EQ + +E + + ++S ++G H
Sbjct: 1923 DSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTR-H 1981
Query: 845 VDNSASGKRVNSNE 858
++S+ G+ +S+E
Sbjct: 1982 TESSSRGQAASSHE 1995
Score = 33.9 bits (76), Expect = 0.85
Identities = 54/263 (20%), Positives = 91/263 (34%), Gaps = 28/263 (10%)
Query: 468 KGQRKDLGRH--RDLVDEDLSHFQSGSPPAPNGFKQHGNPHLYHSQ-----GKGSYKHDR 520
+G R + R+ R +D G P + G +Q YH Q G Y H
Sbjct: 1466 QGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGS----YHEQSVDRSGHSGYHHSH 1521
Query: 521 VVPQSRASAQIISSSKSQILAPGEKITGKVKSDNGTGYDTDSSQDSRDRGNSCDSS--SK 578
PQ R+ A S +S + + + +S +G+ + + R S S +
Sbjct: 1522 TTPQGRSDA---SHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQ 1578
Query: 579 SRNRGWKPMRETLNVDSIFSESEKRQHSPRHKPNISNKPKSSKDPSFSNWPKENPKQKGL 638
+ G K R + S +SE + +++ S NP+
Sbjct: 1579 GESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSH-- 1636
Query: 639 MTIYEDEMKQEIGSRSSLESNGKGAEKNKGLVEGKVHGDNWQMQRTESGYESSDHISNGS 698
ED + SS +S + AE + G G+ Q + + S H +
Sbjct: 1637 ---QEDRASHGHSAESSRQSGTRHAETSSG---GQAASSQEQARSSPGERHGSRHQQSAD 1690
Query: 699 TNLDSPVIDGNGTVMDISGVKET 721
++ DS G G D S V ++
Sbjct: 1691 SSTDS----GTGRRQDSSVVGDS 1709
Score = 32.0 bits (71), Expect = 3.2
Identities = 75/349 (21%), Positives = 128/349 (36%), Gaps = 71/349 (20%)
Query: 397 GDQAKQRENQKFPTDNISSSNRSHSHTGVGKGPAKLSHIDQREKIKDISRECALKAIEQK 456
G+++++ + + S SH TG G + SH E+ +D SR A + + +
Sbjct: 784 GERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSH---HEQARDNSRHSASQ--DGQ 838
Query: 457 NLLSSQRKDLEKGQRKDLGRHRDLVDE-----------------DLSHFQSGSPPAP--- 496
+ + +G++ H VD D S QSGS A
Sbjct: 839 DTIRGHPGSSRRGRQGS--HHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTT 896
Query: 497 -------NGFKQHGNPH---------LYHSQ-GKGSYKHDRVVPQSRASAQIISSSK--- 536
+G + G+ H HSQ G+G + R + +S S S+
Sbjct: 897 RNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHS 956
Query: 537 ------SQILAPGEKITGKVKSDNGTGYDTDSSQDSRDRGNSCDSSSKSRNRGWKPMRET 590
S + + + + +S +G+ + +D G+S DSS +S P ET
Sbjct: 957 EDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGT----PHAET 1012
Query: 591 LNVDSIFSESEKRQHSP--RHKPNISNKPKSSKDPSFSNWPKENPKQKGLMTIYEDEMKQ 648
+ S E+ + SP RH SS+ P+++ + +
Sbjct: 1013 SSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGI-------PRRQASSAVRDSGHWG 1065
Query: 649 EIGSRSSLESNGKGAEKNKGLVEGKVHGDNWQMQRTESGYESSDHISNG 697
GS++S +S G E + V G HG + Q +S ES+ S G
Sbjct: 1066 SSGSQAS-DSEGHSEESDTQSVSG--HGQDGPHQ--QSHQESARDWSGG 1109
>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
Length = 320
Score = 41.6 bits (96), Expect = 0.004
Identities = 57/263 (21%), Positives = 96/263 (36%), Gaps = 38/263 (14%)
Query: 380 CEKPVIHKSDNLKENGFGDQAKQRENQKFPTDNISSSN------RSHSHTGVGKGPAKLS 433
C P K + + G+G +REN ++ S + + G GPA +
Sbjct: 88 CNTPKYAKLE--ERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASI- 144
Query: 434 HIDQREKIKDISRECALKAIEQKNLLSSQRKDLEKGQRKDLGRHRDLVDEDLSHFQSGSP 493
LK +E K + + E + L D D DLS + +
Sbjct: 145 ----------------LKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDAS 188
Query: 494 PAPNGFKQHGNPHLYHSQGKGSYKHDRVVPQSRASAQIISSSKSQILAPGEKITGKVKSD 553
+ K+ N S+ K H R SR+S+ S S+S + + S
Sbjct: 189 EEEDSNKKKSNRR---SRSKSRSSHSR--SSSRSSSPSSSRSRS-------RSRSRSSSS 236
Query: 554 NGTGYDTDSSQDSRDRGNSCDSSSKSRNRGWKPMRETLNVDSIFSESEKRQHSPRHKPNI 613
+ + + S + SR RG+ SSS+S P + + + S E +++ R +
Sbjct: 237 SQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSG 296
Query: 614 SNKPKSSKDPS-FSNWPKENPKQ 635
K + ++ S S EN KQ
Sbjct: 297 DRKKRRTRSRSPESQVIGENTKQ 319
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 41.2 bits (95), Expect = 0.005
Identities = 52/251 (20%), Positives = 91/251 (36%), Gaps = 37/251 (14%)
Query: 380 CEKPVIHKSDNLKENGFGDQAKQRENQKFPTDNISSSN------RSHSHTGVGKGPAKLS 433
C P K + + G+G +REN ++ S + + G GPA +
Sbjct: 88 CNTPKYAKLE--ERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASI- 144
Query: 434 HIDQREKIKDISRECALKAIEQKNLLSSQRKDLEKGQRKDLGRHRDLVDEDLSHFQSGSP 493
LK +E K + + E + L D D DLS + +
Sbjct: 145 ----------------LKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDAS 188
Query: 494 PAPNGFKQHGNPHLYHSQGKGSYKHDRVVPQSRASAQIISSSKSQILAPGEKITGKVKSD 553
+ K+ N S+ K H R SR+S+ S S+S + + S
Sbjct: 189 EEEDSNKKKSNRR---SRSKSRSSHSR--SSSRSSSPSSSRSRS-------RSRSRSSSS 236
Query: 554 NGTGYDTDSSQDSRDRGNSCDSSSKSRNRGWKPMRETLNVDSIFSESEKRQHSPRHKPNI 613
+ + + S + SR RG+ SSS+S P + + + S E +++ R +
Sbjct: 237 SQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSG 296
Query: 614 SNKPKSSKDPS 624
K + ++ S
Sbjct: 297 DRKKRRTRSRS 307
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 40.8 bits (94), Expect = 0.007
Identities = 109/522 (20%), Positives = 187/522 (35%), Gaps = 69/522 (13%)
Query: 350 NPDGTAVSTEDALRQVISWSHYKSVAENMGCEKPVIHKSDNLKENGFGDQAKQRENQKFP 409
N + + +E+ RQ S S + AE P S+N N G ++ E +K P
Sbjct: 76 NLNASDSESEELHRQKDSDSESEERAE------PPASDSENEDVNQHGSDSESEETRKLP 129
Query: 410 TDNISSSNRSHSHTG------VGKGPAKLSHIDQREK--IKDISRECALKA----IEQKN 457
+ + + H VGK PA S I++ +K D E ALK E +
Sbjct: 130 GSDSENEELLNGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESEE 189
Query: 458 LLSSQRKDLEKGQ----RKDLGRHRDLVDEDLSHFQSGSPP----APNGFKQHGNPHLYH 509
Q D E + R +L +S +S PP + + ++ P +
Sbjct: 190 PPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISD 249
Query: 510 SQGKGSYKH------DRVVPQSRAS--------AQIISSSKSQILAPGEKITGKVKSDNG 555
S+ + +H + +P+ R S S S+++ L P +++
Sbjct: 250 SESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEEL-PKPRVSDSESEGPQ 308
Query: 556 TGYDTDSSQDSRDRGNSCDSSSKSRNRGWKPMRETLNVDSIFSES---EKRQHSPRHKPN 612
G +DS + R S +R K + DS S+S K+ HS +
Sbjct: 309 KGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEE 368
Query: 613 ISNKPKSSKDPSFSNWPKENPKQKGLMTIYEDEMKQEIGSRSSL------ESNGKGAEKN 666
K K D +E ++ + + E +++ ++ S +S+
Sbjct: 369 EHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDK 428
Query: 667 KGLVEGKVHGDNWQMQRTESGYESSDHISNGSTNLDSPVIDGN---GTVMDI---SGVKE 720
G E + D+ E+G E SD + S GN + DI SG +E
Sbjct: 429 SGKREKTIASDS----EEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEE 484
Query: 721 TVCFSDQITTSNLNKERGDCTSLQSQHHLEGFRKELRNLEAGYKSHEFHPESHLQIKNHL 780
F+ +L +E+G+ T ++ + R + S +F E LQ K +
Sbjct: 485 EEEFTG-FNQEDLEEEKGE-TQVKEAEDSDSDDNIKRGKHMDFLS-DF--EMMLQRKKSM 539
Query: 781 IKRSHVHEDNGKLFPSS----SLQIPKDHNAREHIHQSDEQK 818
+ + D G + S I K + A E Q + QK
Sbjct: 540 SGKRRRNRDGGTFISDADDVVSAMIVKMNEAAEEDRQLNNQK 581
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 38.9 bits (89), Expect = 0.026
Identities = 69/330 (20%), Positives = 117/330 (35%), Gaps = 55/330 (16%)
Query: 415 SSNRSHSHTGVGKGPAKLSHIDQREKIKDISRECALKAIEQKNLLSSQRKDLEKGQRKDL 474
SS++S T + P+ + R +++ +R + + + + +S+ D+ QR+
Sbjct: 60 SSSKSTKSTSTKRAPS--NRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGT 117
Query: 475 GRHRDLVDEDLSHFQSGSPP---APNGFKQHG-NPHLYH------SQGKGS----YKHDR 520
S SP P + HG P + SQ KGS Y R
Sbjct: 118 HSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPR 177
Query: 521 VVPQSRASAQIISSSKSQILAPGEKITGK----------VKSDNGTGYDTDSSQDSRDRG 570
+ R+ +Q + SK PG G+ K TG + D+
Sbjct: 178 TSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPS 237
Query: 571 NSCDSSS------KSRNRGWKPMRETLNVDSIFS-------ESEKRQHSPRHKPNISNKP 617
+S S SR + + P + V S +S + SPR + S K
Sbjct: 238 SSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKR 297
Query: 618 KSSKDPSFSNWPKENPK-----QKGLMTIYEDEMKQEIGSRSSLESNGKGAEKNKGLVEG 672
S+ S S W + + + +KG+++ ++G S S+ KG +N+
Sbjct: 298 THSRVRSHS-WKRNHSRARSRTRKGILS--------QMGRHSQSRSHSKGKSQNQSRTPR 348
Query: 673 KVHGDNWQMQRTESGYESSDHISNGSTNLD 702
+ NW R S S H + S D
Sbjct: 349 RGRSHNW--SRNPSKERSHSHSRSSSKERD 376
Score = 34.3 bits (77), Expect = 0.65
Identities = 71/303 (23%), Positives = 120/303 (39%), Gaps = 33/303 (10%)
Query: 367 SWSHYKSVAENMGCEKPVIHKSDNLKENG---FGDQAKQRENQKFPTDNISSSNRSHSHT 423
S SH +S ++ E+ S KE+G G KQR++ + + N + +RS S
Sbjct: 364 SHSHSRSSSK----ERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPN-KARDRSRS-- 416
Query: 424 GVGKGPAKL---SHIDQREKIKDISRECALKAIEQKNLLSSQRKDLEKGQRKDLGRHRDL 480
+ P K S K +D SR + ++ S K + + + + RD
Sbjct: 417 ---RSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARD- 472
Query: 481 VDEDLSHFQSGSPPAPNGFKQHGNPHLYHSQGKG-SYKHDRVVPQSRASAQIISSSKSQI 539
+S SP Q G+P + S +R QSR+S++ +S+
Sbjct: 473 ------RSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRS 526
Query: 540 LAPGEKITGKVKSDNGTGYDTDSSQDSRDRGN-SCDSSSKSRNRG-WKPMRETLNVDSIF 597
+ E+ + +S N + S S +R + S SK R+R W+ +
Sbjct: 527 PSK-ERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSR 585
Query: 598 SESEKRQHSPRHKPN----ISNKPKSSKDPSFSNWPKENPKQKGLMTIYEDEMKQEIGSR 653
S SE+R HS PN S SSK+ + S P ++G + K+ S+
Sbjct: 586 SSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSR--SRTPSKEGNHSQSRTSSKESDPSQ 643
Query: 654 SSL 656
S++
Sbjct: 644 STV 646
Score = 31.6 bits (70), Expect = 4.2
Identities = 49/220 (22%), Positives = 86/220 (39%), Gaps = 18/220 (8%)
Query: 486 SHFQSGSPPAPNGFKQHGNPHLYHSQGKG-SYKHDRVVPQSRASAQIISS----SKSQIL 540
SH QS SP + G+ HS+ + S+K + +SR I+S S+S+
Sbjct: 280 SHSQSRSPRR----SRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSH 335
Query: 541 APGEKITGKVKSDNGTGYDTDSSQDSRDRGNSCD-SSSKSRN-RGWKPMRETLNVDSIFS 598
+ G+ G ++ S S++R +S SSSK R+ RG R+ S
Sbjct: 336 SKGKSQNQSRTPRRGRSHNW-SRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGS 394
Query: 599 ESEKRQHSPRHKPN------ISNKPKSSKDPSFSNWPKENPKQKGLMTIYEDEMKQEIGS 652
+++R HS PN S P ++D S S P + + Y+ + S
Sbjct: 395 PNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRS 454
Query: 653 RSSLESNGKGAEKNKGLVEGKVHGDNWQMQRTESGYESSD 692
+ + + NK + + + ++ G S +
Sbjct: 455 PNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKE 494
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 38.9 bits (89), Expect = 0.026
Identities = 105/498 (21%), Positives = 178/498 (35%), Gaps = 95/498 (19%)
Query: 402 QRENQKFPTDNISSSNRSHSHTGVGKGPAKLSHIDQREKIKDISRECALKAIEQKNLLS- 460
QR ++ TD+ S+N S K KLS + R I + + + QK S
Sbjct: 2375 QRNDRDQHTDSTQSANSSPDEDTEVK-TLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSC 2433
Query: 461 --------SQRKDLEKGQ---RKDLGRHRDLVDEDLSHFQSGSPPAPN---------GFK 500
S + LE GQ ++ + +DE L+ G P N G
Sbjct: 2434 KETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLS 2493
Query: 501 QHGNPHLYHSQGKGSYKHDRVVPQSRASAQIISSSKSQILAPGEKITGKVKSDNGTGYDT 560
G P Q +GS K + P+ R ++ K + + +S N +
Sbjct: 2494 MPGVPKAPPMQVEGSAK-ELQAPRKRTVKVTLTPLKME---------NESQSKNALKESS 2543
Query: 561 DSSQDSRDRGNSCDSSSKSRNRGWKPMRETL--NVDSIFSESEKRQHSPRHKPNIS--NK 616
+S + + + S S N G P+ + N S+S Q+ P N+ +
Sbjct: 2544 PASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLPDG 2603
Query: 617 PKSSKDPSFSN-WPKENPKQK-----GLMTIYEDEMKQEIGSRSSLE------SNGKGAE 664
PK +D SF +P+ + + + GL +Y G RS E S+ G +
Sbjct: 2604 PKPQEDGSFKRRYPRRSARARSNMFFGLTPLY--------GVRSYGEEDIPFYSSSTGKK 2655
Query: 665 KNKGLVEGKVHGDNWQMQRTESGYESSDHISNGSTNLDSPVIDGNGTVMDISGVKETVCF 724
+ K EG+V G + +SD N VI G
Sbjct: 2656 RGKRSAEGQVDGAD--------DLSTSDEDDLYYYNFTRTVISSGG-------------- 2693
Query: 725 SDQITTSNLNKERGDCTSLQSQHHLEGFRKELRNLEAGYKSHEFHPESHLQIKNHLIKRS 784
+++ + NL +E C L L+G + ES + K S
Sbjct: 2694 EERLASHNLFREEEQC-DLPKISQLDGV--------------DDGTESDTSVTATTRKSS 2738
Query: 785 HVHEDNGKLFPSSSLQI--PKDHNAREHIHQSDEQKLEKPNECKFSEWLNIENSERTGLP 842
+ + NGK + +L+I P+D +EH+ +S +P ++ + L
Sbjct: 2739 QIPKRNGKENGTENLKIDRPEDAGEKEHVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLE 2798
Query: 843 FHVDNSASGKRVNSNEPS 860
+ + S +RV+++ PS
Sbjct: 2799 AQLSSLESSRRVHTSTPS 2816
>gi|148746183 ubiquitin specific protease 35 [Homo sapiens]
Length = 1018
Score = 38.5 bits (88), Expect = 0.034
Identities = 25/94 (26%), Positives = 45/94 (47%), Gaps = 8/94 (8%)
Query: 39 NSCFLNSAVQVLWQLDIFRRSLRVLTGHVCQGDACIFCALKTIFAQFQHSREKALPSDNI 98
N+C++NS +Q L+ FR + LT + Q + L+ +F +HS+ A+ +N
Sbjct: 448 NTCYVNSILQALFMASDFRHCVLRLTENNSQP---LMTKLQWLFGFLEHSQRPAISPENF 504
Query: 99 RHALAESFKDEQRFQLGLMDDAAECFENMLERIH 132
A + F G D +E + +L+R+H
Sbjct: 505 LSASWTPW-----FSPGTQQDCSEYLKYLLDRLH 533
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 38.1 bits (87), Expect = 0.045
Identities = 43/162 (26%), Positives = 74/162 (45%), Gaps = 10/162 (6%)
Query: 510 SQGKGSYKHDRVVPQSRASAQIISSSKSQILAPGEKITGKVKSDNGTGYDTDSSQ--DSR 567
S+ +G ++ +SR+S+ SSS S + G + S + + S+ SR
Sbjct: 560 SRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSR 619
Query: 568 DRGNSCDSSS--KSRNRGWKPMRETLNVDSIFSESEKRQHSPRHKPNISNKPKSSKDPSF 625
D +S SSS +SR+RG R+ + S+ + ++R S + + S+K SS+D
Sbjct: 620 DSSSSTSSSSESRSRSRGRGHNRDRKHRRSV--DRKRRDTSGLERSHKSSKGGSSRDTKG 677
Query: 626 SNWPKENPKQKGLMTIYEDEMKQEIGSRSSLESNGKGAEKNK 667
S +N + +I E + SRS E + K K+K
Sbjct: 678 SK--DKNSRSDRKRSISESSRSGKRSSRS--ERDRKSDRKDK 715
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 37.7 bits (86), Expect = 0.059
Identities = 107/504 (21%), Positives = 170/504 (33%), Gaps = 77/504 (15%)
Query: 397 GDQAKQRENQKFPTDNISSSNRSHSHTGVGKGPAKLSHI---DQREKIKDISRECALKAI 453
GD K++ ++ N +SN + S G+ P K S D + K K R+ A
Sbjct: 961 GDLGKEKTQKRVKEGN-GTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEG 1019
Query: 454 EQKNLLSSQRK---DLEKGQRKDLGRHRDLVDEDLSHFQSGSPPA-------------PN 497
+ + SS R G K G S +S +PP P
Sbjct: 1020 KSPSHSSSNRPFTPPTSTGGSKSPG----------SAGRSQTPPGVATPPIPKITIQIPK 1069
Query: 498 GFKQHGNPHLYHSQGKGSYKHDRVVPQSRASAQIISSSKSQILAPGEKITGKVKSDNGTG 557
G G P HSQ Y V S + + SS S A +GK+KS G
Sbjct: 1070 GTVMVGKPSS-HSQ----YTSSGSVSSSGSKSHHSHSSSSSSSA---STSGKMKSSKSEG 1121
Query: 558 YDTDSSQDSRDRGNSCDSSSKSRN---RGWKPMRETLNVDSIFSESEKRQHSPRHKPNIS 614
+ S SS+S+N G KP + + S S + P+ KP+
Sbjct: 1122 SSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSL 1181
Query: 615 NKPKSSK---DPSFSNWPKENPKQKGLMTIYEDEMKQEIGSRSSLESNGKGAEKNKGLVE 671
P SK PS S P + K MK G+ S K K +
Sbjct: 1182 MNPSLSKPNISPSHSRPPGGSDK-------LASPMKPVPGTPPS--------SKAKSPIS 1226
Query: 672 GKVHGDNWQMQRTESGYESSDHI-SNGSTNLDSPVIDGNGTVMDISGVKETVCFSDQITT 730
G + + SG +SS + S+GS + +P + T ++
Sbjct: 1227 SGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTA----------------SS 1270
Query: 731 SNLNKERGDCTSLQSQHHLEGFRKELRNLEAGYKSHEFHPESHLQIKNHLIKRSHVHEDN 790
S+ + +S Q+QH + RN + + H + + +
Sbjct: 1271 SSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTA-VIDKLKHGVVTSGPGGEDPLDGQM 1329
Query: 791 GKLFPSSSLQIPKDHNAREHIHQSDEQKLEKPNECKFSEWLNIENSERTGLPFHVDNSAS 850
G SSS + HN Q +K +K + ++++S++T +V ++
Sbjct: 1330 GVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGV 1389
Query: 851 GKRVNSNEPSSLWSSHLRTVGLKP 874
K + S S + KP
Sbjct: 1390 AKIIISKHDGGSPSIKAKVTLQKP 1413
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 37.4 bits (85), Expect = 0.077
Identities = 41/174 (23%), Positives = 73/174 (41%), Gaps = 9/174 (5%)
Query: 514 GSYKHDRVVPQSRASAQIISSSKSQILAPGEKITGKVKSDNGTGYDTDSSQDSRDRGNSC 573
GS K +SR+ + S SKS+ + + K KS + S + SR R +S
Sbjct: 209 GSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRS------PSKEKSRSRSHSA 262
Query: 574 DSS-SKSRNRGWKPMRETLNVDSIFSESEKRQHSPRHKPNISNKPKSSKDPSFSNWPKEN 632
S SKS+++ + ++ NV S S R H + K ++ + ++ + +
Sbjct: 263 GKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR-HKSKSKSRSRSQERRVEEEKRGSVSRGR 321
Query: 633 PKQKGLMTIYEDEMKQEIGSRSSLESNGKGAEKNKGLVEGKVHGDNWQMQRTES 686
++K L + + GSRS S K +K KG + + R++S
Sbjct: 322 SQEKSLRQS-RSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKS 374
Score = 36.6 bits (83), Expect = 0.13
Identities = 61/301 (20%), Positives = 110/301 (36%), Gaps = 33/301 (10%)
Query: 382 KPVIHKSDNLKENG-----FGDQAKQRENQKFPTDNISSSNRSHS-HTGVGK---GPAKL 432
K + K D + NG D+ R + + S +RS S H+ + G +K
Sbjct: 154 KRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKS 213
Query: 433 SHIDQREKIKDISRECALKAIEQKNLLSSQRKDLEKGQRKDLGRHRDLVDEDLSHFQSGS 492
SH R + + SR + K+ + S +K+ + K+ R R SH S
Sbjct: 214 SHSKSRSRSRSGSRSRS-KSRSRSQSRSRSKKEKSRSPSKEKSRSR-------SHSAGKS 265
Query: 493 PPAPNGFKQHGNPHLYHSQGKGSYKHDRVVPQSRASAQIISSSKSQILAPGEKITGKVKS 552
K + ++ G P+SR+ ++ S SKS+ + ++ + +
Sbjct: 266 RSKS---KDQAEEKIQNNDNVGK-------PKSRSPSRHKSKSKSRSRSQERRVEEEKRG 315
Query: 553 DNGTGYDTDSS-QDSRDRGNSCDSSSKSRNRGWKPMRETLNVDSIFSESEKRQHSPRHKP 611
G + S + SR R S S+SR+R ++ E + + R K
Sbjct: 316 SVSRGRSQEKSLRQSRSRSRS-KGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKS 374
Query: 612 NISNKPKSSKDPSFSNWPK----ENPKQKGLMTIYEDEMKQEIGSRSSLESNGKGAEKNK 667
S K S +D + K + + + ++E S + G+G +N
Sbjct: 375 ERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENA 434
Query: 668 G 668
G
Sbjct: 435 G 435
Score = 31.6 bits (70), Expect = 4.2
Identities = 52/269 (19%), Positives = 101/269 (37%), Gaps = 23/269 (8%)
Query: 367 SWSHYKSVAENMGCEKPVIHKSDNLKENGFGDQAKQRENQKFPTDNISSSNRSHSHT-GV 425
S S +S ++ P KS + + ++K ++ + N + + S +
Sbjct: 234 SRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR 293
Query: 426 GKGPAKLSHIDQREKIKDISRECALKAIEQ-KNLLSSQRKDLEKGQRKDLGRHRDLVDE- 483
K +K Q ++++ R + Q K+L S+ + KG + R R +
Sbjct: 294 HKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDK 353
Query: 484 --------DLSHFQSGSPPAPNGFKQHGNPHLYHS-QGKGSYKHDRVVPQSRASAQIISS 534
+ S +S S ++ G+ + K K D QSR+ ++ +S
Sbjct: 354 RKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSK 413
Query: 535 SKSQILAPGEKITGKVKSDN-GTGYDTDSSQDSRDRGN-SCDSSSKSRNRGWKPMRETLN 592
+ + + G+ +S+N GT +T S S + + S S+SR++ R
Sbjct: 414 EREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTR---- 469
Query: 593 VDSIFSESEKRQHSPRHKPNISNKPKSSK 621
S S+ R S P+ S S+
Sbjct: 470 -----SRSKSRSRSASRSPSRSRSRSHSR 493
>gi|161169017 neuron navigator 2 isoform 4 [Homo sapiens]
Length = 1493
Score = 37.4 bits (85), Expect = 0.077
Identities = 57/278 (20%), Positives = 105/278 (37%), Gaps = 34/278 (12%)
Query: 390 NLKENGFGDQAKQRENQKFPTDNISSSNRSHSHTGVGKGPAKLSHIDQREKIKDISRECA 449
N K NG A R ++ +D++SS N + SH+ VG S+I+ K K
Sbjct: 788 NCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVG------SNIESDSKKK------- 834
Query: 450 LKAIEQKNLLSSQRKDL--EKGQRKDLGRHRDLVDEDLSHFQSGSPPAPNGFKQHGNPHL 507
++KN L S K +K K H D+ + S S SP P+ P L
Sbjct: 835 ----KRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPS-SPKLPHNGSTGSTPLL 889
Query: 508 YHSQGKGSYKHDRVVPQSRASAQIISSSKSQILAPGEKITGKVKSDNGTGYDTDSSQDSR 567
+ S+ + + + A+ + ++++ K+T + + D +++
Sbjct: 890 -----RNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAM 944
Query: 568 DRGNSCDSSSKSRNRGWKPMRETLNVD------SIFSESEKRQHSPRHKPNISNKPKSS- 620
+R S K+ N K + SI + + +H N++
Sbjct: 945 NRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDM 1004
Query: 621 --KDPSFSNWPKENPKQKGLMTIYEDEMKQEIGSRSSL 656
D + KE + ++ +++EMK + SR L
Sbjct: 1005 LLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHL 1042
>gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens]
Length = 2365
Score = 37.4 bits (85), Expect = 0.077
Identities = 57/278 (20%), Positives = 105/278 (37%), Gaps = 34/278 (12%)
Query: 390 NLKENGFGDQAKQRENQKFPTDNISSSNRSHSHTGVGKGPAKLSHIDQREKIKDISRECA 449
N K NG A R ++ +D++SS N + SH+ VG S+I+ K K
Sbjct: 1660 NCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVG------SNIESDSKKK------- 1706
Query: 450 LKAIEQKNLLSSQRKDL--EKGQRKDLGRHRDLVDEDLSHFQSGSPPAPNGFKQHGNPHL 507
++KN L S K +K K H D+ + S S SP P+ P L
Sbjct: 1707 ----KRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPS-SPKLPHNGSTGSTPLL 1761
Query: 508 YHSQGKGSYKHDRVVPQSRASAQIISSSKSQILAPGEKITGKVKSDNGTGYDTDSSQDSR 567
+ S+ + + + A+ + ++++ K+T + + D +++
Sbjct: 1762 -----RNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAM 1816
Query: 568 DRGNSCDSSSKSRNRGWKPMRETLNVD------SIFSESEKRQHSPRHKPNISNKPKSS- 620
+R S K+ N K + SI + + +H N++
Sbjct: 1817 NRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDM 1876
Query: 621 --KDPSFSNWPKENPKQKGLMTIYEDEMKQEIGSRSSL 656
D + KE + ++ +++EMK + SR L
Sbjct: 1877 LLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHL 1914
>gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens]
Length = 2429
Score = 37.4 bits (85), Expect = 0.077
Identities = 57/278 (20%), Positives = 105/278 (37%), Gaps = 34/278 (12%)
Query: 390 NLKENGFGDQAKQRENQKFPTDNISSSNRSHSHTGVGKGPAKLSHIDQREKIKDISRECA 449
N K NG A R ++ +D++SS N + SH+ VG S+I+ K K
Sbjct: 1724 NCKGNGTAQSADLRIRRQHSSDSVSSINSATSHSSVG------SNIESDSKKK------- 1770
Query: 450 LKAIEQKNLLSSQRKDL--EKGQRKDLGRHRDLVDEDLSHFQSGSPPAPNGFKQHGNPHL 507
++KN L S K +K K H D+ + S S SP P+ P L
Sbjct: 1771 ----KRKNWLRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPS-SPKLPHNGSTGSTPLL 1825
Query: 508 YHSQGKGSYKHDRVVPQSRASAQIISSSKSQILAPGEKITGKVKSDNGTGYDTDSSQDSR 567
+ S+ + + + A+ + ++++ K+T + + D +++
Sbjct: 1826 -----RNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAM 1880
Query: 568 DRGNSCDSSSKSRNRGWKPMRETLNVD------SIFSESEKRQHSPRHKPNISNKPKSS- 620
+R S K+ N K + SI + + +H N++
Sbjct: 1881 NRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSISASPRQSMGLSQHSLNLTESTSLDM 1940
Query: 621 --KDPSFSNWPKENPKQKGLMTIYEDEMKQEIGSRSSL 656
D + KE + ++ +++EMK + SR L
Sbjct: 1941 LLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHL 1978
>gi|239746654 PREDICTED: ubiquitin specific protease 41 [Homo
sapiens]
Length = 347
Score = 37.0 bits (84), Expect = 0.100
Identities = 29/118 (24%), Positives = 52/118 (44%), Gaps = 14/118 (11%)
Query: 227 NCGQKIKIRRVLM--NCPEIVTIGLVWDSEHSDLTEAVV------RNLATHLYLPGLFYR 278
NCG+K + ++VL + P+ +TI L+ S + T + ++L LP
Sbjct: 221 NCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILPMKRES 280
Query: 279 VTDENAKNSELNLVGMICYT----SQHYCAFAFHTKSSKWVFFDDANVKEIGTRWKDV 332
E + L +I + S HYC + + KW F+D+N+ + W+D+
Sbjct: 281 CDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVS--WEDI 336
>gi|32313610 ubiquitin specific protease 18 [Homo sapiens]
Length = 372
Score = 37.0 bits (84), Expect = 0.100
Identities = 29/118 (24%), Positives = 52/118 (44%), Gaps = 14/118 (11%)
Query: 227 NCGQKIKIRRVLM--NCPEIVTIGLVWDSEHSDLTEAVV------RNLATHLYLPGLFYR 278
NCG+K + ++VL + P+ +TI L+ S + T + ++L LP
Sbjct: 232 NCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILPMKRES 291
Query: 279 VTDENAKNSELNLVGMICYT----SQHYCAFAFHTKSSKWVFFDDANVKEIGTRWKDV 332
E + L +I + S HYC + + KW F+D+N+ + W+D+
Sbjct: 292 CDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLVS--WEDI 347
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 36.6 bits (83), Expect = 0.13
Identities = 66/313 (21%), Positives = 105/313 (33%), Gaps = 50/313 (15%)
Query: 369 SHYKSVAENMGCEKPVIHKSDNLKENGFGDQA--KQRENQKFPTDNISSSNRSHSHTGVG 426
SH + V+E CE S++ KE A + +E K PT T +
Sbjct: 497 SHSQKVSETQMCE------SNSSKETSLATPAGKESQEGPKHPTGPFFPVLSKDESTAL- 549
Query: 427 KGPAKLSHIDQREKIKDISRECALKAIEQKNLLSSQRKDLEKGQRKDLGRHRDLVDEDLS 486
+ P++L + E IS C + K LS + KG K +D+
Sbjct: 550 QWPSELLIFTKAEP--SISYSCNPLYFDFK--LSRNKDARTKGTEKP----KDIGSSSKD 601
Query: 487 HFQSGSPPAPNGFKQHGNPHLYHSQGKGSYKHDRVVPQSRASAQIISSSKSQILAPGEKI 546
H Q P PN K+ G + S G + A G
Sbjct: 602 HLQGLDPGEPNKSKEVGGEKIVRSSG----------------------GRMDAPASGSAC 639
Query: 547 TGKVKSDNGTGYDTDSSQDSRDRGNSCDSSSKSRNRGWKPM---------RETLNVDSIF 597
+G K + G + +++ R + + S KS K + + +
Sbjct: 640 SGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKS 699
Query: 598 SESEKRQHSPRHKPNISNKPKSSKDPSFSNWPKENPKQKGLMTIYEDEMK-QEIGSRSSL 656
S++E + S + K K KSS PK P G + Q+ R SL
Sbjct: 700 SKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSL 759
Query: 657 ES-NGKGAEKNKG 668
+ G +K++G
Sbjct: 760 PAEEGSSGKKDEG 772
Score = 30.8 bits (68), Expect = 7.2
Identities = 73/361 (20%), Positives = 137/361 (37%), Gaps = 45/361 (12%)
Query: 367 SWSHYKSVAENMGCEKPVIHKSDNLKENGFGDQAKQRENQKFPTDN---ISSSNRSHSHT 423
S+S + + C SD+ + + D++++ + +D+ SS +RS H
Sbjct: 869 SYSSSSDASSDQSCYSRQRSYSDD-SYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHK 927
Query: 424 -GVGKGPAKLSHIDQREKIKDISRECALKAIEQKNLLSSQRKDLEKGQRKDLGRHRDLVD 482
LS R + + +RE + ++ SS + K + + H
Sbjct: 928 YSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRS--SSCSRSRSKRRSRSTTAHSWQRS 985
Query: 483 EDLSHFQSGSPPAPN---GFKQ----HGNPHLYHSQGKGSYKHDRVVPQSRASAQIISSS 535
S +S S +P+ G ++ H +P HS G+ + ++ S S
Sbjct: 986 RSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHS-GRRDFIRSKIYRSQ--SPHYFRSG 1042
Query: 536 KSQILAPGEKITGKVKSDNGTGYDTDSSQDSRDRGNSCDSSSKSRNRGWKPMRETLNVDS 595
+ + PG+K G+ TG + +S RG+ D S + +N + L ++
Sbjct: 1043 RGE--GPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDKN----SVTAKLLLEK 1096
Query: 596 IFSESEKRQHSPRHKPNISNKPKSSKDPSFSNWPKENPKQKG-LMTIYEDEMKQEIGSRS 654
I S +R KP++S + +++ + K PK K + ++ +G++
Sbjct: 1097 IQSRKVER------KPSVSEEVQATPN-------KAGPKLKDPPQGYFGPKLPPSLGNKP 1143
Query: 655 SLESNGK---GAEKNKGLVE-GKVHGDNWQMQRTESGYESSDHISNG----STNLDSPVI 706
L GK + NK E G G+ + TE G S G S P++
Sbjct: 1144 VLPLIGKLPATRKPNKKCEESGLERGEEQEQSETEEGPPGSSDALFGHQFPSEETTGPLL 1203
Query: 707 D 707
D
Sbjct: 1204 D 1204
>gi|239757637 PREDICTED: ubiquitin specific peptidase 41 [Homo
sapiens]
Length = 344
Score = 36.2 bits (82), Expect = 0.17
Identities = 29/118 (24%), Positives = 51/118 (43%), Gaps = 14/118 (11%)
Query: 227 NCGQKIKIRRVLM--NCPEIVTIGLVWDSEHSDLTEAVV------RNLATHLYLPGLFYR 278
NCG+K + ++VL + P+ +TI L+ S + T + ++L LP
Sbjct: 198 NCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILPMKRES 257
Query: 279 VTDENAKNSELNLVGMICYT----SQHYCAFAFHTKSSKWVFFDDANVKEIGTRWKDV 332
E + L +I + S HYC + KW F+D+N+ + W+D+
Sbjct: 258 CDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRSAVDGKWFCFNDSNICLVS--WEDI 313
>gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens]
Length = 525
Score = 36.2 bits (82), Expect = 0.17
Identities = 40/156 (25%), Positives = 62/156 (39%), Gaps = 15/156 (9%)
Query: 30 KGLLNEPGQNSCFLNSAVQVLWQLDIFRRSLRVLTGHVCQ---GDACIFCALKTIFAQFQ 86
+GL+N N+CF+N VQ L + R + H C+ +C+ C + ++F +F
Sbjct: 176 RGLINLG--NTCFMNCIVQALTHTPLL-RDFFLSDRHRCEMQSPSSCLVCEMSSLFQEFY 232
Query: 87 HSREKALPSDNIRHALAESFKDEQRFQLGL-MDDAAECFENMLERIHFHIV---PSRDAD 142
S +I + L R G DA E L+ +H H + A+
Sbjct: 233 SGHR----SPHIPYKLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDNGKKAN 288
Query: 143 MCTSKSCITHQKFAMTLYEQCVCRSC-GASSDPLPF 177
+CI Q F L C+ C G S+ PF
Sbjct: 289 NPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPF 324
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 36.2 bits (82), Expect = 0.17
Identities = 38/149 (25%), Positives = 60/149 (40%), Gaps = 19/149 (12%)
Query: 513 KGSYKHDRVVPQSRASAQIISSSKSQILAPGEKITGKV---KSDNGTGYDTDSSQDSRDR 569
K YK D+ +R ++ KS+ L K K KSD+ G + DSS + + R
Sbjct: 998 KEKYKSDKDSTSTRLERKLSDGHKSRSLKHSSKDIKKKDENKSDDKDGKEVDSSHE-KAR 1056
Query: 570 GNSCDSSSKSRNRGWKPMRETLNVDSIFSESEKRQHSPRHKPNISNKPKSSKDPSFSNWP 629
GNS K R + R +L+ E + + N + P S
Sbjct: 1057 GNSSLMEKKLSRRLCENRRGSLS-------QEMAKGEEKLAANTLSTPSGSS-------- 1101
Query: 630 KENPKQKGLMTIYEDEMKQEIGSRSSLES 658
+ PK+ G MT+ ++ EI S +E+
Sbjct: 1102 LQRPKKSGDMTLIPEQEPMEIDSEPGVEN 1130
>gi|33620755 YEATS domain containing 2 [Homo sapiens]
Length = 1422
Score = 36.2 bits (82), Expect = 0.17
Identities = 31/121 (25%), Positives = 49/121 (40%), Gaps = 9/121 (7%)
Query: 883 QNIMDQCYFENSLSTECIIRSASRSDGCQMPKLFCQNLPPPLPPKKYAITSVPQSEKSES 942
+ ++D +SL +CI +S SD P +P P+ S P + E
Sbjct: 322 ETVVDVELHRHSLGEDCIYPQSSESDISDAPPSLPLTIPAPVK------ASSPIKQSHEP 375
Query: 943 TPDVKLTEVFKATSHLPKHSLSTASEPSLEVSTHMNDERHKETFQVRECFGNTPNCPSSS 1002
PD + + F A++ +H+ A SLE + K TF GN+ P +S
Sbjct: 376 VPDTSVEKGFPASTEAERHTPFYALPSSLERTPTKMTTSQKVTFC---SHGNSAFQPIAS 432
Query: 1003 S 1003
S
Sbjct: 433 S 433
>gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens]
Length = 438
Score = 35.4 bits (80), Expect = 0.29
Identities = 36/146 (24%), Positives = 58/146 (39%), Gaps = 14/146 (9%)
Query: 30 KGLLNEPGQNSCFLNSAVQVLWQLDIFRRSLRVLTGHVCQ---GDACIFCALKTIFAQFQ 86
+GL+N N+CF+N VQ L I R + H C+ + C+ C + ++F +
Sbjct: 78 RGLINLG--NTCFMNCIVQALTHTPIL-RDFFLSDRHRCEMPSPELCLVCEMSSLFRELY 134
Query: 87 HSREKALPSDNIRHALAESFKDEQRFQLGL-MDDAAECFENMLERIHFHIV---PSRDAD 142
PS ++ + L R G DA E L+ +H H + A+
Sbjct: 135 SGN----PSPHVPYKLLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRHCKGDDVGKAAN 190
Query: 143 MCTSKSCITHQKFAMTLYEQCVCRSC 168
+CI Q F L C++C
Sbjct: 191 NPNHCNCIIDQIFTGGLQSDVTCQAC 216
>gi|169215723 PREDICTED: ubiquitin specific peptidase 41 [Homo
sapiens]
Length = 346
Score = 35.4 bits (80), Expect = 0.29
Identities = 28/123 (22%), Positives = 54/123 (43%), Gaps = 16/123 (13%)
Query: 227 NCGQKIKIRRVLM--NCPEIVTIGLVWDSEHSDLTEAVV------RNLATHLYLPGLFYR 278
NCG+K + ++VL + P+ +TI L+ S + T + ++L LP
Sbjct: 221 NCGKKTRGKQVLKLTHLPQTLTIHLMRFSIRNSQTRKICHSLYFPQSLDFSQILPMKRES 280
Query: 279 VTDENAKNSELNLVGMICYT----SQHYCAFAFHTKSSKWVFFDDANVKEIGTRWKDVVS 334
E + L +I + S HYC + + KW F+D+N+ + ++++
Sbjct: 281 CDAEEQSGGQYELFAVIAHVGMADSGHYCVYIRNAVDGKWFCFNDSNICLV----RNIIH 336
Query: 335 KCI 337
C+
Sbjct: 337 NCL 339
>gi|221316624 dystonin isoform 4 [Homo sapiens]
Length = 5526
Score = 35.4 bits (80), Expect = 0.29
Identities = 30/134 (22%), Positives = 59/134 (44%), Gaps = 28/134 (20%)
Query: 436 DQREKIKDISR--ECALKAIEQKNLLSSQRKDLEKGQRKDLGRHRDLVDEDLSHFQSGSP 493
++ EK+ + + E K + LS+ KD E+ K H+ +++++ +HFQ G
Sbjct: 1704 EETEKVAAVKQLEESKTKIENLLDWLSNVDKDSERAGTK----HKQVIEQNGTHFQEGDG 1759
Query: 494 PAPNGFKQHGNPHLYHSQGKGSY----------------KHDRVVPQSRA------SAQI 531
+ G + N +L + G +H++++ Q +A SAQ+
Sbjct: 1760 KSAIGEEDEVNGNLLETDVDGQVGTTQENLNQQYQKVKAQHEKIISQHQAVIIATQSAQV 1819
Query: 532 ISSSKSQILAPGEK 545
+ + Q L+P EK
Sbjct: 1820 LLEKQGQYLSPEEK 1833
>gi|221316622 dystonin isoform 3 [Homo sapiens]
Length = 5537
Score = 35.4 bits (80), Expect = 0.29
Identities = 30/134 (22%), Positives = 59/134 (44%), Gaps = 28/134 (20%)
Query: 436 DQREKIKDISR--ECALKAIEQKNLLSSQRKDLEKGQRKDLGRHRDLVDEDLSHFQSGSP 493
++ EK+ + + E K + LS+ KD E+ K H+ +++++ +HFQ G
Sbjct: 1715 EETEKVAAVKQLEESKTKIENLLDWLSNVDKDSERAGTK----HKQVIEQNGTHFQEGDG 1770
Query: 494 PAPNGFKQHGNPHLYHSQGKGSY----------------KHDRVVPQSRA------SAQI 531
+ G + N +L + G +H++++ Q +A SAQ+
Sbjct: 1771 KSAIGEEDEVNGNLLETDVDGQVGTTQENLNQQYQKVKAQHEKIISQHQAVIIATQSAQV 1830
Query: 532 ISSSKSQILAPGEK 545
+ + Q L+P EK
Sbjct: 1831 LLEKQGQYLSPEEK 1844
>gi|221316618 dystonin isoform 2 [Homo sapiens]
Length = 5675
Score = 35.4 bits (80), Expect = 0.29
Identities = 30/134 (22%), Positives = 59/134 (44%), Gaps = 28/134 (20%)
Query: 436 DQREKIKDISR--ECALKAIEQKNLLSSQRKDLEKGQRKDLGRHRDLVDEDLSHFQSGSP 493
++ EK+ + + E K + LS+ KD E+ K H+ +++++ +HFQ G
Sbjct: 1853 EETEKVAAVKQLEESKTKIENLLDWLSNVDKDSERAGTK----HKQVIEQNGTHFQEGDG 1908
Query: 494 PAPNGFKQHGNPHLYHSQGKGSY----------------KHDRVVPQSRA------SAQI 531
+ G + N +L + G +H++++ Q +A SAQ+
Sbjct: 1909 KSAIGEEDEVNGNLLETDVDGQVGTTQENLNQQYQKVKAQHEKIISQHQAVIIATQSAQV 1968
Query: 532 ISSSKSQILAPGEK 545
+ + Q L+P EK
Sbjct: 1969 LLEKQGQYLSPEEK 1982
>gi|34577047 dystonin isoform 1 [Homo sapiens]
Length = 5497
Score = 35.4 bits (80), Expect = 0.29
Identities = 30/134 (22%), Positives = 59/134 (44%), Gaps = 28/134 (20%)
Query: 436 DQREKIKDISR--ECALKAIEQKNLLSSQRKDLEKGQRKDLGRHRDLVDEDLSHFQSGSP 493
++ EK+ + + E K + LS+ KD E+ K H+ +++++ +HFQ G
Sbjct: 1675 EETEKVAAVKQLEESKTKIENLLDWLSNVDKDSERAGTK----HKQVIEQNGTHFQEGDG 1730
Query: 494 PAPNGFKQHGNPHLYHSQGKGSY----------------KHDRVVPQSRA------SAQI 531
+ G + N +L + G +H++++ Q +A SAQ+
Sbjct: 1731 KSAIGEEDEVNGNLLETDVDGQVGTTQENLNQQYQKVKAQHEKIISQHQAVIIATQSAQV 1790
Query: 532 ISSSKSQILAPGEK 545
+ + Q L+P EK
Sbjct: 1791 LLEKQGQYLSPEEK 1804
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,362,002
Number of Sequences: 37866
Number of extensions: 2119237
Number of successful extensions: 7330
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 142
Number of HSP's that attempted gapping in prelim test: 7008
Number of HSP's gapped (non-prelim): 347
length of query: 1073
length of database: 18,247,518
effective HSP length: 113
effective length of query: 960
effective length of database: 13,968,660
effective search space: 13409913600
effective search space used: 13409913600
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.