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Search of human proteins with 14589942
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens]
(1037 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens] 2056 0.0
gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens] 2037 0.0
gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens] 2029 0.0
gi|14589918 protocadherin 11 X-linked isoform b precursor [Homo ... 1971 0.0
gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo s... 1961 0.0
gi|14589922 protocadherin 11 X-linked isoform d [Homo sapiens] 1961 0.0
gi|14589920 protocadherin 11 X-linked isoform c [Homo sapiens] 1961 0.0
gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens] 1176 0.0
gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens] 1176 0.0
gi|27754773 protocadherin 1 isoform 2 precursor [Homo sapiens] 654 0.0
gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens] 654 0.0
gi|190194360 protocadherin 20 [Homo sapiens] 623 e-178
gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens] 607 e-173
gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens] 607 e-173
gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens] 583 e-166
gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precur... 365 e-100
gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precur... 365 e-100
gi|14589929 protocadherin 18 precursor [Homo sapiens] 360 4e-99
gi|157426847 protocadherin 19 isoform a [Homo sapiens] 355 1e-97
gi|157426845 protocadherin 19 isoform b [Homo sapiens] 355 1e-97
gi|94538350 protocadherin 17 precursor [Homo sapiens] 355 2e-97
gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precurs... 352 8e-97
gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precur... 352 8e-97
gi|14270490 protocadherin gamma subfamily B, 1 isoform 2 precurs... 349 9e-96
gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precurs... 349 9e-96
gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens] 348 2e-95
gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens] 348 2e-95
gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precurs... 346 6e-95
gi|14196477 protocadherin gamma subfamily A, 7 isoform 2 precurs... 346 6e-95
gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precur... 345 1e-94
>gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens]
Length = 1037
Score = 2056 bits (5328), Expect = 0.0
Identities = 1037/1037 (100%), Positives = 1037/1037 (100%)
Query: 1 MTVGFNSDISSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVL 60
MTVGFNSDISSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVL
Sbjct: 1 MTVGFNSDISSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVL 60
Query: 61 IGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAG 120
IGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAG
Sbjct: 61 IGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAG 120
Query: 121 IPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYT 180
IPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYT
Sbjct: 121 IPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYT 180
Query: 181 LPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKV 240
LPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKV
Sbjct: 181 LPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKV 240
Query: 241 KVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIG 300
KVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIG
Sbjct: 241 KVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIG 300
Query: 301 ENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARA 360
ENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARA
Sbjct: 301 ENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARA 360
Query: 361 MVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCF 420
MVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCF
Sbjct: 361 MVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCF 420
Query: 421 TDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDE 480
TDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDE
Sbjct: 421 TDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDE 480
Query: 481 NDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRT 540
NDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRT
Sbjct: 481 NDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRT 540
Query: 541 GMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYV 600
GMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYV
Sbjct: 541 GMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYV 600
Query: 601 PENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESY 660
PENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESY
Sbjct: 601 PENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESY 660
Query: 661 TFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVI 720
TFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVI
Sbjct: 661 TFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVI 720
Query: 721 AVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP 780
AVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP
Sbjct: 721 AVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQP 780
Query: 781 DSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVA 840
DSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVA
Sbjct: 781 DSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVA 840
Query: 841 GTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPK 900
GTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPK
Sbjct: 841 GTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPK 900
Query: 901 NLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHY 960
NLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHY
Sbjct: 901 NLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHY 960
Query: 961 KSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVT 1020
KSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVT
Sbjct: 961 KSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVT 1020
Query: 1021 TFEVPVSVHTRPTDSRT 1037
TFEVPVSVHTRPTDSRT
Sbjct: 1021 TFEVPVSVHTRPTDSRT 1037
>gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens]
Length = 1048
Score = 2037 bits (5278), Expect = 0.0
Identities = 1027/1027 (100%), Positives = 1027/1027 (100%)
Query: 11 SVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNL 70
SVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNL
Sbjct: 22 SVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNL 81
Query: 71 SLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYE 130
SLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYE
Sbjct: 82 SLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYE 141
Query: 131 VEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVG 190
VEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVG
Sbjct: 142 VEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVG 201
Query: 191 INGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQR 250
INGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQR
Sbjct: 202 INGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQR 261
Query: 251 SSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFS 310
SSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFS
Sbjct: 262 SSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFS 321
Query: 311 NLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVN 370
NLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVN
Sbjct: 322 NLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVN 381
Query: 371 DNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 430
DNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR
Sbjct: 382 DNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 441
Query: 431 PVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQS 490
PVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQS
Sbjct: 442 PVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQS 501
Query: 491 FVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLD 550
FVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLD
Sbjct: 502 FVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLD 561
Query: 551 REKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTV 610
REKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTV
Sbjct: 562 REKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTV 621
Query: 611 GLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG 670
GLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG
Sbjct: 622 GLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG 681
Query: 671 RVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNA 730
RVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNA
Sbjct: 682 RVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNA 741
Query: 731 EVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVN 790
EVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVN
Sbjct: 742 EVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVN 801
Query: 791 LFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIF 850
LFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIF
Sbjct: 802 LFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIF 861
Query: 851 ITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIE 910
ITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIE
Sbjct: 862 ITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIE 921
Query: 911 ETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQ 970
ETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQ
Sbjct: 922 ETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQ 981
Query: 971 IQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHT 1030
IQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHT
Sbjct: 982 IQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHT 1041
Query: 1031 RPTDSRT 1037
RPTDSRT
Sbjct: 1042 RPTDSRT 1048
>gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens]
Length = 1340
Score = 2029 bits (5258), Expect = 0.0
Identities = 1023/1026 (99%), Positives = 1024/1026 (99%)
Query: 11 SVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNL 70
SVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNL
Sbjct: 22 SVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNL 81
Query: 71 SLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYE 130
SLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYE
Sbjct: 82 SLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYE 141
Query: 131 VEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVG 190
VEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVG
Sbjct: 142 VEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVG 201
Query: 191 INGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQR 250
INGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQR
Sbjct: 202 INGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQR 261
Query: 251 SSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFS 310
SSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFS
Sbjct: 262 SSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFS 321
Query: 311 NLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVN 370
NLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVN
Sbjct: 322 NLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVN 381
Query: 371 DNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 430
DNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR
Sbjct: 382 DNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 441
Query: 431 PVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQS 490
PVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQS
Sbjct: 442 PVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQS 501
Query: 491 FVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLD 550
FVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLD
Sbjct: 502 FVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLD 561
Query: 551 REKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTV 610
REKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTV
Sbjct: 562 REKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTV 621
Query: 611 GLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG 670
GLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG
Sbjct: 622 GLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG 681
Query: 671 RVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNA 730
RVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNA
Sbjct: 682 RVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNA 741
Query: 731 EVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVN 790
EVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVN
Sbjct: 742 EVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVN 801
Query: 791 LFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIF 850
LFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIF
Sbjct: 802 LFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIF 861
Query: 851 ITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIE 910
ITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIE
Sbjct: 862 ITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIE 921
Query: 911 ETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQ 970
ETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQ
Sbjct: 922 ETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQ 981
Query: 971 IQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHT 1030
IQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHT
Sbjct: 982 IQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHT 1041
Query: 1031 RPTDSR 1036
RP+ R
Sbjct: 1042 RPSQRR 1047
>gi|14589918 protocadherin 11 X-linked isoform b precursor [Homo
sapiens]
Length = 1025
Score = 1971 bits (5106), Expect = 0.0
Identities = 997/1014 (98%), Positives = 1000/1014 (98%)
Query: 24 LLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQ 83
LLSGTYIFAVLL CVVFHSGAQEKNYTIREE+PENVLIG+LLKDLNLSLIPNKSLTT MQ
Sbjct: 3 LLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQ 62
Query: 84 FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 143
FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL
Sbjct: 63 FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 122
Query: 144 VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 203
VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ
Sbjct: 123 VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 182
Query: 204 NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 263
NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT
Sbjct: 183 NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 242
Query: 264 NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 323
NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL
Sbjct: 243 NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 302
Query: 324 NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 383
NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN
Sbjct: 303 NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 362
Query: 384 PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAA 443
PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLE AA
Sbjct: 363 PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAA 422
Query: 444 YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 503
YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG
Sbjct: 423 YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 482
Query: 504 IQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILA 563
IQL KVSA DADSGPNA+INYLLGPDAPPEFSLD RTGMLTVVKKLDREKEDKYLFTILA
Sbjct: 483 IQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILA 542
Query: 564 KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDN 623
KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEY FYVPENLPRHGTVGLITVTDPDYGDN
Sbjct: 543 KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDN 602
Query: 624 SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 683
SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN
Sbjct: 603 SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 662
Query: 684 VVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 743
VVDVNDNKPVFIVPP N SYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD
Sbjct: 663 VVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 722
Query: 744 LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 803
LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI
Sbjct: 723 LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 782
Query: 804 NELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 863
NELVRKS EAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL
Sbjct: 783 NELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 842
Query: 864 KAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNR 923
KAAQKN QNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLN VTIEETKADDVDSDGNR
Sbjct: 843 KAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNR 902
Query: 924 VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNLKHHI 983
VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLN KHHI
Sbjct: 903 VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHI 962
Query: 984 IQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPTDSRT 1037
IQELPLDNTFVACDSIS CSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPTDSRT
Sbjct: 963 IQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPTDSRT 1016
>gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo
sapiens]
Length = 1021
Score = 1961 bits (5081), Expect = 0.0
Identities = 992/1009 (98%), Positives = 995/1009 (98%)
Query: 24 LLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQ 83
LLSGTYIFAVLL CVVFHSGAQEKNYTIREE+PENVLIG+LLKDLNLSLIPNKSLTT MQ
Sbjct: 3 LLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQ 62
Query: 84 FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 143
FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL
Sbjct: 63 FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 122
Query: 144 VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 203
VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ
Sbjct: 123 VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 182
Query: 204 NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 263
NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT
Sbjct: 183 NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 242
Query: 264 NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 323
NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL
Sbjct: 243 NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 302
Query: 324 NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 383
NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN
Sbjct: 303 NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 362
Query: 384 PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAA 443
PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLE AA
Sbjct: 363 PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAA 422
Query: 444 YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 503
YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG
Sbjct: 423 YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 482
Query: 504 IQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILA 563
IQL KVSA DADSGPNA+INYLLGPDAPPEFSLD RTGMLTVVKKLDREKEDKYLFTILA
Sbjct: 483 IQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILA 542
Query: 564 KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDN 623
KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEY FYVPENLPRHGTVGLITVTDPDYGDN
Sbjct: 543 KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDN 602
Query: 624 SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 683
SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN
Sbjct: 603 SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 662
Query: 684 VVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 743
VVDVNDNKPVFIVPP N SYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD
Sbjct: 663 VVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 722
Query: 744 LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 803
LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI
Sbjct: 723 LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 782
Query: 804 NELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 863
NELVRKS EAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL
Sbjct: 783 NELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 842
Query: 864 KAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNR 923
KAAQKN QNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLN VTIEETKADDVDSDGNR
Sbjct: 843 KAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNR 902
Query: 924 VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNLKHHI 983
VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLN KHHI
Sbjct: 903 VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHI 962
Query: 984 IQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP 1032
IQELPLDNTFVACDSIS CSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP
Sbjct: 963 IQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP 1011
>gi|14589922 protocadherin 11 X-linked isoform d [Homo sapiens]
Length = 1337
Score = 1961 bits (5081), Expect = 0.0
Identities = 992/1009 (98%), Positives = 995/1009 (98%)
Query: 24 LLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQ 83
LLSGTYIFAVLL CVVFHSGAQEKNYTIREE+PENVLIG+LLKDLNLSLIPNKSLTT MQ
Sbjct: 3 LLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQ 62
Query: 84 FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 143
FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL
Sbjct: 63 FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 122
Query: 144 VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 203
VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ
Sbjct: 123 VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 182
Query: 204 NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 263
NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT
Sbjct: 183 NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 242
Query: 264 NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 323
NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL
Sbjct: 243 NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 302
Query: 324 NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 383
NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN
Sbjct: 303 NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 362
Query: 384 PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAA 443
PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLE AA
Sbjct: 363 PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAA 422
Query: 444 YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 503
YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG
Sbjct: 423 YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 482
Query: 504 IQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILA 563
IQL KVSA DADSGPNA+INYLLGPDAPPEFSLD RTGMLTVVKKLDREKEDKYLFTILA
Sbjct: 483 IQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILA 542
Query: 564 KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDN 623
KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEY FYVPENLPRHGTVGLITVTDPDYGDN
Sbjct: 543 KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDN 602
Query: 624 SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 683
SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN
Sbjct: 603 SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 662
Query: 684 VVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 743
VVDVNDNKPVFIVPP N SYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD
Sbjct: 663 VVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 722
Query: 744 LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 803
LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI
Sbjct: 723 LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 782
Query: 804 NELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 863
NELVRKS EAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL
Sbjct: 783 NELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 842
Query: 864 KAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNR 923
KAAQKN QNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLN VTIEETKADDVDSDGNR
Sbjct: 843 KAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNR 902
Query: 924 VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNLKHHI 983
VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLN KHHI
Sbjct: 903 VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHI 962
Query: 984 IQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP 1032
IQELPLDNTFVACDSIS CSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP
Sbjct: 963 IQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP 1011
>gi|14589920 protocadherin 11 X-linked isoform c [Homo sapiens]
Length = 1347
Score = 1961 bits (5081), Expect = 0.0
Identities = 992/1009 (98%), Positives = 995/1009 (98%)
Query: 24 LLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQ 83
LLSGTYIFAVLL CVVFHSGAQEKNYTIREE+PENVLIG+LLKDLNLSLIPNKSLTT MQ
Sbjct: 3 LLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQ 62
Query: 84 FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 143
FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL
Sbjct: 63 FKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRL 122
Query: 144 VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 203
VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ
Sbjct: 123 VKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQ 182
Query: 204 NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 263
NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT
Sbjct: 183 NIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDT 242
Query: 264 NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 323
NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL
Sbjct: 243 NDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHL 302
Query: 324 NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 383
NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN
Sbjct: 303 NATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVN 362
Query: 384 PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAA 443
PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLE AA
Sbjct: 363 PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAA 422
Query: 444 YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 503
YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG
Sbjct: 423 YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 482
Query: 504 IQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILA 563
IQL KVSA DADSGPNA+INYLLGPDAPPEFSLD RTGMLTVVKKLDREKEDKYLFTILA
Sbjct: 483 IQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILA 542
Query: 564 KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDN 623
KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEY FYVPENLPRHGTVGLITVTDPDYGDN
Sbjct: 543 KDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDN 602
Query: 624 SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 683
SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN
Sbjct: 603 SAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTIN 662
Query: 684 VVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 743
VVDVNDNKPVFIVPP N SYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD
Sbjct: 663 VVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRD 722
Query: 744 LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 803
LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI
Sbjct: 723 LFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 782
Query: 804 NELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 863
NELVRKS EAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL
Sbjct: 783 NELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHL 842
Query: 864 KAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNR 923
KAAQKN QNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLN VTIEETKADDVDSDGNR
Sbjct: 843 KAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGNR 902
Query: 924 VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNLKHHI 983
VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLN KHHI
Sbjct: 903 VTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNSKHHI 962
Query: 984 IQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP 1032
IQELPLDNTFVACDSIS CSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP
Sbjct: 963 IQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRP 1011
>gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens]
Length = 1203
Score = 1176 bits (3043), Expect = 0.0
Identities = 588/1017 (57%), Positives = 778/1017 (76%), Gaps = 16/1017 (1%)
Query: 29 YIFAVLLVCVVFHSG-AQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTT-TMQFKL 86
Y+ A L+ C+ S AQE YTIREE+PENV IGN+ KDLN+S I + T+ ++ ++L
Sbjct: 7 YLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRL 66
Query: 87 VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIP--RDEHCFYEVEVAILPDEIFRLV 144
V K GD PL+++ TGEIFTT RIDREKLCAG + CF+E+EV ILP++ FRL+
Sbjct: 67 VSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLI 126
Query: 145 KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQN 204
KI+ +++D NDNAP+FP+ VINISIPEN+ INS++ +P+A DPD G NGVQ+YEL+ Q+
Sbjct: 127 KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQS 186
Query: 205 IFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTN 264
+FGLD++ETPEG+K PQLIVQ+ LDRE+KDTYVMK+KVEDGG PQ+SSTAILQV+V+D N
Sbjct: 187 VFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVN 246
Query: 265 DNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLN 324
DN PVFKE ++EV IPENAPVGTSV QLHATDADIG NA+I + F V+ +RLF LN
Sbjct: 247 DNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALN 306
Query: 325 ATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNP 384
TTGLIT++ LDREET HK+ VLASDG PARA V +NVTDVNDN P+ID+RYI++P
Sbjct: 307 NTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISP 366
Query: 385 VNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAY 444
+N TV LSE P+NTKIALITV+DKD D NG+V CF + E+PF L+ V+ NQ+LLE ++
Sbjct: 367 INGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSL 426
Query: 445 LDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGI 504
LDYE TKE++ K++A+D+GKP LNQ+A++ +K++DENDN P+F Q + +S+ ENN G+
Sbjct: 427 LDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGL 486
Query: 505 QLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAK 564
L +SATD DSG NA+I Y LGP+A F LDR+TG+LT + DRE++++++FT+ A+
Sbjct: 487 YLTTISATDEDSGKNADIVYQLGPNA-SFFDLDRKTGVLTASRVFDREEQERFIFTVTAR 545
Query: 565 DNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNS 624
DNG PPL S V V+++D+NDNSP FTHN ++F+V ENLP++ TVG+ITVTD D G+N
Sbjct: 546 DNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENK 605
Query: 625 AVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINV 684
AVTLSIL++ND+F +D +GVI+ N+SFDRE+Q SYTF VKA DGG+ RSS+AKVTINV
Sbjct: 606 AVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINV 665
Query: 685 VDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL 744
+DVNDN PV I PP N S++LV S PG+VV +V AVD DTGMNAE++Y+IV GN + L
Sbjct: 666 MDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGL 725
Query: 745 FAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLIN 804
F ID TGNITL EK TD+GLHR++V +DLG P SL ++V+V L+VN++ NA+ I
Sbjct: 726 FRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNASYIY 785
Query: 805 ELVRKSIEAPVTPNTEIADVSSP--TSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPH 862
+L+R+++E P+ N I D S P DY+ I++A +AG + V+VVIF+T +VRCR A
Sbjct: 786 DLIRRTMETPLDRN--IGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRHASR 843
Query: 863 LKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGN 922
KAAQ++ Q +EW +PN EN+Q KKKK+KK+ SPK+ LLN VTIEE+K DD +
Sbjct: 844 FKAAQRSKQGAEWMSPNQENKQ---NKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 900
Query: 923 RVTLDLPIDLEEQTMGKYNW-VTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNL-K 980
T+ LP +LEEQ++G+++W PTTFKP+SPDLA+HYKSASPQPAF ++P+TP+++ K
Sbjct: 901 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 960
Query: 981 HHIIQELPLDNTFV-ACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPTDSR 1036
HH+IQELPLDNTFV CD++S SS+SSD +S S+C F+ +HTR + R
Sbjct: 961 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECS-SQGGFKTKGPLHTRQSQRR 1016
>gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens]
Length = 1237
Score = 1176 bits (3043), Expect = 0.0
Identities = 588/1018 (57%), Positives = 779/1018 (76%), Gaps = 16/1018 (1%)
Query: 29 YIFAVLLVCVVFHSG-AQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTT-TMQFKL 86
Y+ A L+ C+ S AQE YTIREE+PENV IGN+ KDLN+S I + T+ ++ ++L
Sbjct: 7 YLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRL 66
Query: 87 VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIP--RDEHCFYEVEVAILPDEIFRLV 144
V K GD PL+++ TGEIFTT RIDREKLCAG + CF+E+EV ILP++ FRL+
Sbjct: 67 VSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLI 126
Query: 145 KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQN 204
KI+ +++D NDNAP+FP+ VINISIPEN+ INS++ +P+A DPD G NGVQ+YEL+ Q+
Sbjct: 127 KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQS 186
Query: 205 IFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTN 264
+FGLD++ETPEG+K PQLIVQ+ LDRE+KDTYVMK+KVEDGG PQ+SSTAILQV+V+D N
Sbjct: 187 VFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVN 246
Query: 265 DNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLN 324
DN PVFKE ++EV IPENAPVGTSV QLHATDADIG NA+I + F V+ +RLF LN
Sbjct: 247 DNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALN 306
Query: 325 ATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNP 384
TTGLIT++ LDREET HK+ VLASDG PARA V +NVTDVNDN P+ID+RYI++P
Sbjct: 307 NTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISP 366
Query: 385 VNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAY 444
+N TV LSE P+NTKIALITV+DKD D NG+V CF + E+PF L+ V+ NQ+LLE ++
Sbjct: 367 INGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSL 426
Query: 445 LDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGI 504
LDYE TKE++ K++A+D+GKP LNQ+A++ +K++DENDN P+F Q + +S+ ENN G+
Sbjct: 427 LDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGL 486
Query: 505 QLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAK 564
L +SATD DSG NA+I Y LGP+A F LDR+TG+LT + DRE++++++FT+ A+
Sbjct: 487 YLTTISATDEDSGKNADIVYQLGPNA-SFFDLDRKTGVLTASRVFDREEQERFIFTVTAR 545
Query: 565 DNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNS 624
DNG PPL S V V+++D+NDNSP FTHN ++F+V ENLP++ TVG+ITVTD D G+N
Sbjct: 546 DNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENK 605
Query: 625 AVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINV 684
AVTLSIL++ND+F +D +GVI+ N+SFDRE+Q SYTF VKA DGG+ RSS+AKVTINV
Sbjct: 606 AVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINV 665
Query: 685 VDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL 744
+DVNDN PV I PP N S++LV S PG+VV +V AVD DTGMNAE++Y+IV GN + L
Sbjct: 666 MDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGL 725
Query: 745 FAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLIN 804
F ID TGNITL EK TD+GLHR++V +DLG P SL ++V+V L+VN++ NA+ I
Sbjct: 726 FRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNASYIY 785
Query: 805 ELVRKSIEAPVTPNTEIADVSSP--TSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPH 862
+L+R+++E P+ N I D S P DY+ I++A +AG + V+VVIF+T +VRCR A
Sbjct: 786 DLIRRTMETPLDRN--IGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRHASR 843
Query: 863 LKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGN 922
KAAQ++ Q +EW +PN EN+Q KKKK+KK+ SPK+ LLN VTIEE+K DD +
Sbjct: 844 FKAAQRSKQGAEWMSPNQENKQ---NKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 900
Query: 923 RVTLDLPIDLEEQTMGKYNW-VTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNL-K 980
T+ LP +LEEQ++G+++W PTTFKP+SPDLA+HYKSASPQPAF ++P+TP+++ K
Sbjct: 901 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 960
Query: 981 HHIIQELPLDNTFV-ACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPTDSRT 1037
HH+IQELPLDNTFV CD++S SS+SSD +S S+C F+ +HTR +S +
Sbjct: 961 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECS-SQGGFKTKGPLHTRQCNSHS 1017
>gi|27754773 protocadherin 1 isoform 2 precursor [Homo sapiens]
Length = 1237
Score = 654 bits (1687), Expect = 0.0
Identities = 399/1012 (39%), Positives = 571/1012 (56%), Gaps = 51/1012 (5%)
Query: 24 LLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQ 83
LL + + A+LL+ A Y + EE P N LIG+L D + +
Sbjct: 37 LLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGH-------- 88
Query: 84 FKLVYKTG-DVPLIRIEEDTGEIFTTGARIDREKL--CAGIPRDEHCFYEVEVAI---LP 137
+YK P +R++ TG+IFTT IDRE L C + C E EV+I +
Sbjct: 89 ---LYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQ 145
Query: 138 DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNY 197
+ RL++ + ++DINDN P F + VI ++IPEN+ I S + +P A D D G NGV +Y
Sbjct: 146 NGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASY 205
Query: 198 ELI---KSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTA 254
EL ++Q +FGL V E E +K PQLIV LDRE D+Y + +KV+DGG P R+S+A
Sbjct: 206 ELQAGPEAQELFGLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSA 264
Query: 255 ILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVS 314
+L+V+V DTNDN P F+ E + EN+P+G SV Q+ A D+D G NA+I ++F
Sbjct: 265 LLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ-AP 323
Query: 315 NIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDN 372
+ RRL L+ TGLIT++ P+DRE+ + VLA D G P ARA V+V V D+NDN
Sbjct: 324 EVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDN 383
Query: 373 VPSIDIRYI--VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 430
P+I+IR I V + +SE++ T +AL+ V+D+D N VTC ++PF+LR
Sbjct: 384 APTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLR 443
Query: 431 PVFSN------QFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNA 484
++ L+ LDYE K+Y I+++A D+G PPL+ + L ++V D NDNA
Sbjct: 444 QASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNA 503
Query: 485 PVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPE--FSLDRRTGM 542
PVFTQS V+ PENN PG + +++A+DADSG NAE+ Y L P+ + F++ TG
Sbjct: 504 PVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGE 563
Query: 543 LTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPE 602
+ V LDRE+ + Y ++A D G P L TV V+++D NDN P F + Y F V E
Sbjct: 564 IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVME 623
Query: 603 NLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTF 662
N+P VG++TV D D G+N+ V LS+ +N DF I + TG I ++SFDRE+Q +YTF
Sbjct: 624 NMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTF 683
Query: 663 YVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAV 722
+KA DGG RS+ VTINV+D NDN P +I P N S++L+ P T G V QV A
Sbjct: 684 QLKAVDGGVPPRSAYVGVTINVLDENDNAP-YITAPSNTSHKLLTPQTRLGETVSQVAAE 742
Query: 723 DNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDS 782
D D+G+NAE+ YSI GGN LF I +G ITL ++ + GLHR++VK +D G+P
Sbjct: 743 DFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPR 802
Query: 783 LFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGT 842
+ +V+L+VNE++ N TL+ L+ S++ P+ + + IL VAG
Sbjct: 803 -YGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGV 861
Query: 843 ITVVVVIFITAVVR-CRQAPHLKAAQK-NMQNSEWATPNPENRQMIMMKKKKKKKKHSPK 900
+ V ++I + +VR CRQ Q + + P P + K K KK K SPK
Sbjct: 862 VAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSK-SPK 920
Query: 901 NLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHY 960
V +E D D + L +L G + P + P SPDL RHY
Sbjct: 921 ----PVKPVE-------DEDEAGLQKSLKFNLMSDAPGDSPRIHLPLNYPPGSPDLGRHY 969
Query: 961 KSASPQPAFQIQPETP-LNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYS 1011
+S SP P+ Q+QP++P + KH ++Q+LP NTFV ++ S YS
Sbjct: 970 RSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDYS 1021
>gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens]
Length = 1060
Score = 654 bits (1687), Expect = 0.0
Identities = 399/1012 (39%), Positives = 571/1012 (56%), Gaps = 51/1012 (5%)
Query: 24 LLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQ 83
LL + + A+LL+ A Y + EE P N LIG+L D + +
Sbjct: 37 LLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGH-------- 88
Query: 84 FKLVYKTG-DVPLIRIEEDTGEIFTTGARIDREKL--CAGIPRDEHCFYEVEVAI---LP 137
+YK P +R++ TG+IFTT IDRE L C + C E EV+I +
Sbjct: 89 ---LYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQ 145
Query: 138 DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNY 197
+ RL++ + ++DINDN P F + VI ++IPEN+ I S + +P A D D G NGV +Y
Sbjct: 146 NGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASY 205
Query: 198 ELI---KSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTA 254
EL ++Q +FGL V E E +K PQLIV LDRE D+Y + +KV+DGG P R+S+A
Sbjct: 206 ELQAGPEAQELFGLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSA 264
Query: 255 ILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVS 314
+L+V+V DTNDN P F+ E + EN+P+G SV Q+ A D+D G NA+I ++F
Sbjct: 265 LLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ-AP 323
Query: 315 NIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDN 372
+ RRL L+ TGLIT++ P+DRE+ + VLA D G P ARA V+V V D+NDN
Sbjct: 324 EVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDN 383
Query: 373 VPSIDIRYI--VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 430
P+I+IR I V + +SE++ T +AL+ V+D+D N VTC ++PF+LR
Sbjct: 384 APTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLR 443
Query: 431 PVFSN------QFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNA 484
++ L+ LDYE K+Y I+++A D+G PPL+ + L ++V D NDNA
Sbjct: 444 QASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNA 503
Query: 485 PVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPE--FSLDRRTGM 542
PVFTQS V+ PENN PG + +++A+DADSG NAE+ Y L P+ + F++ TG
Sbjct: 504 PVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGE 563
Query: 543 LTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPE 602
+ V LDRE+ + Y ++A D G P L TV V+++D NDN P F + Y F V E
Sbjct: 564 IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVME 623
Query: 603 NLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTF 662
N+P VG++TV D D G+N+ V LS+ +N DF I + TG I ++SFDRE+Q +YTF
Sbjct: 624 NMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTF 683
Query: 663 YVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAV 722
+KA DGG RS+ VTINV+D NDN P +I P N S++L+ P T G V QV A
Sbjct: 684 QLKAVDGGVPPRSAYVGVTINVLDENDNAP-YITAPSNTSHKLLTPQTRLGETVSQVAAE 742
Query: 723 DNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDS 782
D D+G+NAE+ YSI GGN LF I +G ITL ++ + GLHR++VK +D G+P
Sbjct: 743 DFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPR 802
Query: 783 LFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGT 842
+ +V+L+VNE++ N TL+ L+ S++ P+ + + IL VAG
Sbjct: 803 -YGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGV 861
Query: 843 ITVVVVIFITAVVR-CRQAPHLKAAQK-NMQNSEWATPNPENRQMIMMKKKKKKKKHSPK 900
+ V ++I + +VR CRQ Q + + P P + K K KK K SPK
Sbjct: 862 VAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSK-SPK 920
Query: 901 NLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHY 960
V +E D D + L +L G + P + P SPDL RHY
Sbjct: 921 ----PVKPVE-------DEDEAGLQKSLKFNLMSDAPGDSPRIHLPLNYPPGSPDLGRHY 969
Query: 961 KSASPQPAFQIQPETP-LNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYS 1011
+S SP P+ Q+QP++P + KH ++Q+LP NTFV ++ S YS
Sbjct: 970 RSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDYS 1021
>gi|190194360 protocadherin 20 [Homo sapiens]
Length = 951
Score = 623 bits (1606), Expect = e-178
Identities = 345/820 (42%), Positives = 503/820 (61%), Gaps = 43/820 (5%)
Query: 29 YIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVY 88
++F C+ +S A E Y++ E +P VLIG+L +DL L +P + Q +L
Sbjct: 50 FLFVGPFSCLGSYSRATELLYSLNEGLPAGVLIGSLAEDLRL--LPRSAGRPDPQSQLPE 107
Query: 89 KTG---DVPL-------------IRIEEDTGEIFTTGARIDREKLC-------------- 118
+TG + PL + ++ +GE+ T+ IDRE LC
Sbjct: 108 RTGAEWNPPLSFSLASRGLSGQYVTLDNRSGELHTSAQEIDREALCVEGGGGTAWSGSVS 167
Query: 119 -AGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINS 177
+ P D C ++V +LP E FR VK++ I DINDNAP FP + I++ +PEN+ +N+
Sbjct: 168 ISSSPSDS-CLLLLDVLVLPQEYFRFVKVKIAIRDINDNAPQFPVSQISVWVPENAPVNT 226
Query: 178 KYTLP-AAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTY 236
+ + AVDPDVGINGVQ Y L+ +F LDV E G++ P LIV LDRE +D Y
Sbjct: 227 RLAIEHPAVDPDVGINGVQTYRLLDYHGMFTLDVEENENGERTPYLIVMGALDRETQDQY 286
Query: 237 VMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATD 296
V + EDGG P +A L + ++D NDN P+F +++I V++ NA VGT + + A D
Sbjct: 287 VSIIIAEDGGSPPLLGSATLTIGISDINDNCPLFTDSQINVTVYGNATVGTPIAAVQAVD 346
Query: 297 ADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLM 356
D+G NA+I +S+S V ++ LFHL+ TG+I + + +HKL +LA+ G +
Sbjct: 347 KDLGTNAQITYSYSQKVPQASKDLFHLDENTGVIKLFSKIGGSVLESHKLTILANGPGCI 406
Query: 357 PARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGR 416
PA LV++ V P I RYI N ++ V L E P+NT IA T+ D + + +
Sbjct: 407 PAVITALVSIIKVIFRPPEIVPRYIANEIDGVVYLKELEPVNTPIAFFTIRDPEGKY--K 464
Query: 417 VTCFTDHEIPFRLRPV--FSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLF 474
V C+ D E PFRL P ++N++LLE +DYE + Y + ++A ++ + ++
Sbjct: 465 VNCYLDGEGPFRLSPYKPYNNEYLLETTKPMDYELQQFYEVAVVAWNS--EGFHVKRVIK 522
Query: 475 IKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEF 534
+++ D+NDNAP+F Q + ++I ENNSP L K+ ATDADS +++Y LGPDAP F
Sbjct: 523 VQLLDDNDNAPIFLQPLIELTIEENNSPNAFLTKLYATDADSEERGQVSYFLGPDAPSYF 582
Query: 535 SLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHN 594
SLD TG+LTV +LDRE+++KY +T+ A D G PP S TV ++++D+NDNSP F +
Sbjct: 583 SLDSVTGILTVSTQLDREEKEKYRYTVRAVDCGKPPRESVATVALTVLDKNDNSPRFINK 642
Query: 595 EYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDR 654
++ F+VPEN P +G +G+I+VTD D G N V LS+++++D F ID+ G++R +S DR
Sbjct: 643 DFSFFVPENFPGYGEIGVISVTDADAGRNGWVALSVVNQSDIFVIDTGKGMLRAKVSLDR 702
Query: 655 EKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGT 714
E+Q SYT +V+A DGG + SS+AK+TI ++D+NDN P+ + P N SY LVLPST PG+
Sbjct: 703 EQQSSYTLWVEAVDGGEPALSSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGS 762
Query: 715 VVFQVIAVDNDTGMNAEVRYSIVG--GNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLV 772
V +V AVD DTGMNA + YSI+G G + F ID +TGNITL E TD GLHR+LV
Sbjct: 763 PVTEVYAVDKDTGMNAVIAYSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLV 822
Query: 773 KANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIE 812
K +D G P+ L S V+VNLFVN++V+N + I L+RK E
Sbjct: 823 KVSDHGYPEPLHSTVMVNLFVNDTVSNESYIESLLRKEPE 862
>gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens]
Length = 1072
Score = 607 bits (1564), Expect = e-173
Identities = 383/1033 (37%), Positives = 571/1033 (55%), Gaps = 95/1033 (9%)
Query: 49 YTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTT 108
Y + EE P +V IGN+ DL + +T + + ++G ++I+ TGE+ T+
Sbjct: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87
Query: 109 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 164
RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V
Sbjct: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147
Query: 165 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELI----------KSQNIFGLDVIETP 214
+ +++ EN + + Y LP A D D G NG++ YEL+ +S+ D P
Sbjct: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207
Query: 215 EG-------------------------------DKMPQLIVQKELDREEKDTYVMK---- 239
G + +L V D E++ ++K
Sbjct: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALD 267
Query: 240 ----------VKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 289
++V DGG P RSS AIL+V +TD NDN P F+++ E + EN+ GT +
Sbjct: 268 REQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI 327
Query: 290 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 349
QL A D D+G N +I + F ++ RRL L+ T+G +++ +DREE + V+
Sbjct: 328 LQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVLHRIDREEVNQLRFTVM 386
Query: 350 ASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV-LSENIPLNTKIALIT 405
A D G P +A V++N+ D NDNVPSI+IR I P+ D V ++E++ ++T IAL+
Sbjct: 387 ARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 446
Query: 406 VTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLENAAYLDYESTKEYAIKLL 458
V+D+D NG VTC ++PF+L+P + + L + LDYE+T+E+ + ++
Sbjct: 447 VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 506
Query: 459 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGP 518
A D+G P L+ + L +KV D NDN P+F QS V V PENN PG ++ V ATDADSG
Sbjct: 507 AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 566
Query: 519 NAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVF 578
NAEI Y L F++D +G + V LDRE+ D+Y F + AKD G+P L + TV
Sbjct: 567 NAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626
Query: 579 VSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFT 638
V + D+NDN P F + + FYV ENL + VG++TV D D G N+ ++L I + N+ F+
Sbjct: 627 VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFS 686
Query: 639 IDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP 698
I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++ V+D NDN P + P
Sbjct: 687 IENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-VTLP 745
Query: 699 YNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLME 758
N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN LF ID +G ++L+
Sbjct: 746 KNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVG 805
Query: 759 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPN 818
K GLHR++V+ ND GQP S + +V++FVNESV+NAT I+ + +S+ P+T +
Sbjct: 806 KLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQD 864
Query: 819 TEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAPHLKAAQKNMQNSEWAT 877
+ + I++ VAG +TV+++I I + R CR + ++ T
Sbjct: 865 IAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFT 924
Query: 878 PNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTM 937
P ++ K KK KK P L ++VT+E +K + D L + +M
Sbjct: 925 PQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSM 977
Query: 938 GKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNLKHHIIQELPLDNTFV-A 995
G+Y V P SPDLARHYKS+SP P Q+ P++P KH +Q+LP NTFV A
Sbjct: 978 GRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033
Query: 996 CDSISNCSSSSSD 1008
D+IS S S+
Sbjct: 1034 GDNISIGSDHCSE 1046
>gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens]
Length = 1069
Score = 607 bits (1564), Expect = e-173
Identities = 383/1033 (37%), Positives = 571/1033 (55%), Gaps = 95/1033 (9%)
Query: 49 YTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTT 108
Y + EE P +V IGN+ DL + +T + + ++G ++I+ TGE+ T+
Sbjct: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87
Query: 109 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 164
RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V
Sbjct: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147
Query: 165 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELI----------KSQNIFGLDVIETP 214
+ +++ EN + + Y LP A D D G NG++ YEL+ +S+ D P
Sbjct: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207
Query: 215 EG-------------------------------DKMPQLIVQKELDREEKDTYVMK---- 239
G + +L V D E++ ++K
Sbjct: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALD 267
Query: 240 ----------VKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV 289
++V DGG P RSS AIL+V +TD NDN P F+++ E + EN+ GT +
Sbjct: 268 REQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI 327
Query: 290 TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL 349
QL A D D+G N +I + F ++ RRL L+ T+G +++ +DREE + V+
Sbjct: 328 LQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVLHRIDREEVNQLRFTVM 386
Query: 350 ASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV-LSENIPLNTKIALIT 405
A D G P +A V++N+ D NDNVPSI+IR I P+ D V ++E++ ++T IAL+
Sbjct: 387 ARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQ 446
Query: 406 VTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLENAAYLDYESTKEYAIKLL 458
V+D+D NG VTC ++PF+L+P + + L + LDYE+T+E+ + ++
Sbjct: 447 VSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIV 506
Query: 459 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGP 518
A D+G P L+ + L +KV D NDN P+F QS V V PENN PG ++ V ATDADSG
Sbjct: 507 AVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGK 566
Query: 519 NAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVF 578
NAEI Y L F++D +G + V LDRE+ D+Y F + AKD G+P L + TV
Sbjct: 567 NAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVI 626
Query: 579 VSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFT 638
V + D+NDN P F + + FYV ENL + VG++TV D D G N+ ++L I + N+ F+
Sbjct: 627 VQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFS 686
Query: 639 IDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPP 698
I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++ V+D NDN P + P
Sbjct: 687 IENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPT-VTLP 745
Query: 699 YNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLME 758
N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN LF ID +G ++L+
Sbjct: 746 KNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVG 805
Query: 759 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPN 818
K GLHR++V+ ND GQP S + +V++FVNESV+NAT I+ + +S+ P+T +
Sbjct: 806 KLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQD 864
Query: 819 TEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAPHLKAAQKNMQNSEWAT 877
+ + I++ VAG +TV+++I I + R CR + ++ T
Sbjct: 865 IAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFT 924
Query: 878 PNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTM 937
P ++ K KK KK P L ++VT+E +K + D L + +M
Sbjct: 925 PQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSM 977
Query: 938 GKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNLKHHIIQELPLDNTFV-A 995
G+Y V P SPDLARHYKS+SP P Q+ P++P KH +Q+LP NTFV A
Sbjct: 978 GRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033
Query: 996 CDSISNCSSSSSD 1008
D+IS S S+
Sbjct: 1034 GDNISIGSDHCSE 1046
>gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens]
Length = 1200
Score = 583 bits (1504), Expect = e-166
Identities = 377/1016 (37%), Positives = 561/1016 (55%), Gaps = 55/1016 (5%)
Query: 49 YTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTT 108
Y + EE P +V IGN+ DL + +T + + ++G ++I+ TGE+ T+
Sbjct: 36 YRLAEEGPADVRIGNVASDLGI-------VTGSGEVTFSLESGS-EYLKIDNLTGELSTS 87
Query: 109 GARIDREKL--CAGIPRDEHCFYEVEVAIL-PDEIF-RLVKIRFLIEDINDNAPLFPATV 164
RIDREKL C I + CF + EV+++ P + + L + + ++ DINDN P FP+ V
Sbjct: 88 ERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPV 147
Query: 165 INISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK----------SQNIFGLDVIETP 214
+ +++ EN + + Y LP A D D G NG++ YEL++ S+ D P
Sbjct: 148 LTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYP 207
Query: 215 EGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP-VFKET 273
G + D GG RSS LQV+ T + P + +
Sbjct: 208 GGGGNGASGGGSGGSKRRLDASEGGGGTNPGG---RSSVFELQVADTPDGEKQPQLIVKG 264
Query: 274 EIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK 333
E + EN+ GT + QL A D D+G N +I + F ++ RRL L+ T+G +++
Sbjct: 265 VYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESV-RRLLRLDETSGWLSVL 323
Query: 334 EPLDREETPNHKLLVLASDGGLMPA--RAMVLVNVTDVNDNVPSIDIRYIVN-PVNDTVV 390
+DREE + V+A D G P +A V++N+ D NDNVPSI+IR I P+ D V
Sbjct: 324 HRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVA 383
Query: 391 -LSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQ-------FLLENA 442
++E++ ++T IAL+ V+D+D NG VTC ++PF+L+P + + L +
Sbjct: 384 NVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTS 443
Query: 443 AYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSP 502
LDYE+T+E+ + ++A D+G P L+ + L +KV D NDN P+F QS V V PENN P
Sbjct: 444 TPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIP 503
Query: 503 GIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTIL 562
G ++ V ATDADSG NAEI Y L F++D +G + V LDRE+ D+Y F +
Sbjct: 504 GERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVN 563
Query: 563 AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGD 622
AKD G+P L + TV V + D+NDN P F + + FYV ENL + VG++TV D D G
Sbjct: 564 AKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGR 623
Query: 623 NSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTI 682
N+ ++L I + N+ F+I++ TG I +SFDRE Q +YTF VKA DGG RS++A V++
Sbjct: 624 NAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSL 683
Query: 683 NVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTR 742
V+D NDN P + P N SY L+ PS+N TVV V+A D+D G+NA++ YSIVGGN
Sbjct: 684 FVMDENDNAPT-VTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPF 742
Query: 743 DLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATL 802
LF ID +G ++L+ K GLHR++V+ ND GQP S + +V++FVNESV+NAT
Sbjct: 743 KLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVFVNESVSNATA 801
Query: 803 INELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR-CRQAP 861
I+ + +S+ P+T + + + I++ VAG +TV+++I I + R CR
Sbjct: 802 IDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKN 861
Query: 862 HLKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDG 921
+ ++ TP ++ K KK KK P L ++VT+E +K + D
Sbjct: 862 KNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQP--LYSSIVTVEASKPNGQRYDS 919
Query: 922 NRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHYKSASPQPAFQIQPETP-LNLK 980
L + +MG+Y V P SPDLARHYKS+SP P Q+ P++P K
Sbjct: 920 VNEKLS-----DSPSMGRYRSVNG----GPGSPDLARHYKSSSPLPTVQLHPQSPTAGKK 970
Query: 981 HHIIQELPLDNTFV-ACDSISNCSSSSSDPYSVSDCGYPVTTF-EVPVSVHTRPTD 1034
H +Q+LP NTFV A D+IS S S+ ++ Y F V SV ++P D
Sbjct: 971 HQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQTNNKYSKQPFRRVTFSVVSQPQD 1026
>gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precursor
[Homo sapiens]
Length = 936
Score = 365 bits (937), Expect = e-100
Identities = 235/681 (34%), Positives = 356/681 (52%), Gaps = 54/681 (7%)
Query: 33 VLLVCVVF----HSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVY 88
++L+C+ F +GA++ +Y+I EE+ + +GN+ KDL L+ P + ++ +
Sbjct: 17 LVLLCLFFGIPWEAGARQISYSIPEELEKGSFVGNISKDLGLA--PRELAERGVR---IV 71
Query: 89 KTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRF 148
G L + +G + T G RIDRE+LCA R C V IL ++ +L I
Sbjct: 72 SRGRTQLFSLNPRSGSLITAG-RIDREELCAQSAR---CV--VSFNILVEDRVKLFGIEI 125
Query: 149 LIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGL 208
+ DINDNAP F A +++ I EN A ++ LP A+DPDVG+N +Q+Y+L +++ F L
Sbjct: 126 EVTDINDNAPKFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKH-FSL 184
Query: 209 DVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP 268
V G K P+L+++ LDREE+ + + + DGG P RS T ++ V+V D NDN P
Sbjct: 185 RVQSRANGVKYPELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAP 244
Query: 269 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 328
VF E VS+PEN PVGT + + ATD D G N ++ +SF L + F LN TG
Sbjct: 245 VFTLPEYRVSVPENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLLK-FQLNKYTG 303
Query: 329 LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT 388
I I E LD EET +++ + A DGG A A VL+ V DVNDN P + I + +PV
Sbjct: 304 EIKISENLDYEETGFYEIEIQAEDGGAYLATAKVLITVEDVNDNSPELTITSLFSPV--- 360
Query: 389 VVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYE 448
+E+ PL T +AL+ V D D++ NG+VTC +PF+L + + L LD E
Sbjct: 361 ---TEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDRE 417
Query: 449 STKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMK 508
Y I + A D G PPL+ A ++V D NDN P F+Q IPENN+ G +
Sbjct: 418 QVSSYNITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFS 477
Query: 509 VSATDADSGPNAEINYLLGPDA------PPEFSLDRRTGMLTVVKKLDREKEDKYLFTIL 562
V+A D DS NA+I Y L D S++ TG+L ++ D E+ + +
Sbjct: 478 VTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVT 537
Query: 563 AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGL---------- 612
A D+G PPL+SNV++ + ++DQNDN+P + LP G+ G+
Sbjct: 538 ASDSGDPPLSSNVSLSLFVLDQNDNAPEILY--------PALPTDGSTGVELAPRSAEPG 589
Query: 613 -----ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVK 665
+ D D G N+ ++ +L ++ F + TG +R + + V
Sbjct: 590 YLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVA 649
Query: 666 AEDGGRVSRSSSAKVTINVVD 686
+D G+ S++ +T+ V D
Sbjct: 650 VQDHGQPPLSATVTLTVAVAD 670
Score = 242 bits (618), Expect = 1e-63
Identities = 197/670 (29%), Positives = 312/670 (46%), Gaps = 71/670 (10%)
Query: 222 LIVQKELDREE------KDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEI 275
LI +DREE + + VED R +++ VTD NDN P F+ +
Sbjct: 88 LITAGRIDREELCAQSARCVVSFNILVED-----RVKLFGIEIEVTDINDNAPKFQAENL 142
Query: 276 EVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEP 335
+V I EN G A D D+G N+ + S + F L + +K P
Sbjct: 143 DVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLS------PNKHFSLRVQSRANGVKYP 196
Query: 336 -------LDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 386
LDREE H L++ ASDGG L +V V V D NDN P +
Sbjct: 197 ELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEY----- 251
Query: 387 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIP------FRLRPVFSNQFLLE 440
V + EN+P+ T++ +T TD+D NG VT ++ ++P F+L + E
Sbjct: 252 -RVSVPENLPVGTQLLTVTATDRDEGANGEVT-YSFRKLPDTQLLKFQLNKYTGEIKISE 309
Query: 441 NAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENN 500
N LDYE T Y I++ A D G +A + I V+D NDN+P T + + + E++
Sbjct: 310 N---LDYEETGFYEIEIQAEDGGA--YLATAKVLITVEDVNDNSPELTITSLFSPVTEDS 364
Query: 501 SPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGM---LTVVKKLDREKEDKY 557
G + ++ D DS N ++ + P F L++ L + + LDRE+ Y
Sbjct: 365 PLGTVVALLNVHDLDSEQNGQVTCSILAYLP--FKLEKSIDSYYRLVIHRALDREQVSSY 422
Query: 558 LFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTD 617
T+ A D G PPL++ + + D NDN P F+ Y Y+PEN R ++ +T D
Sbjct: 423 NITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALD 482
Query: 618 PDYGDNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG 670
PD +N+ + S+ ++ + +I+S TGV+ SFD E+ V A D G
Sbjct: 483 PDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSG 542
Query: 671 RVSRSSSAKVTINVVDVNDNKPVFIVPPY----NYSYELVLPSTNPGTVVFQVIAVDNDT 726
SS+ +++ V+D NDN P + P + EL S PG +V +V+AVD D+
Sbjct: 543 DPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDS 602
Query: 727 GMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSV 786
G NA + Y ++ + LFA+ + TG + D ++V D GQP L +
Sbjct: 603 GQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQP-PLSAT 661
Query: 787 VIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVV 846
V + + V +S+ ++ +L S E+P N+E +D++ Y+ + VAAV+
Sbjct: 662 VTLTVAVADSIPQ--VLADL--GSFESPA--NSETSDLTL----YLVVAVAAVSCVFLAF 711
Query: 847 VVIFITAVVR 856
V++ + +R
Sbjct: 712 VIVLLAHRLR 721
Score = 108 bits (270), Expect = 3e-23
Identities = 93/306 (30%), Positives = 137/306 (44%), Gaps = 30/306 (9%)
Query: 534 FSLDRRTGMLTVVKKLDREK------EDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDN 587
FSL+ R+G L ++DRE+ F IL +D + + + D NDN
Sbjct: 79 FSLNPRSGSLITAGRIDREELCAQSARCVVSFNILVEDR-----VKLFGIEIEVTDINDN 133
Query: 588 SPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQT---G 644
+P F + EN+ L DPD G NS + L N F++ Q+ G
Sbjct: 134 APKFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQ-LSPNKHFSLRVQSRANG 192
Query: 645 VIRPNI----SFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYN 700
V P + S DRE++ + + A DGG RS + V++ V D NDN PVF +P Y
Sbjct: 193 VKYPELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYR 252
Query: 701 YSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL--FAIDQETGNITLME 758
S LP GT + V A D D G N EV YS L F +++ TG I + E
Sbjct: 253 VSVPENLP---VGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLLKFQLNKYTGEIKISE 309
Query: 759 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPN 818
D + G + + ++A D G + V+I VN++ EL S+ +PVT +
Sbjct: 310 NLDYEETGFYEIEIQAEDGGAYLATAKVLITVEDVNDNSP------ELTITSLFSPVTED 363
Query: 819 TEIADV 824
+ + V
Sbjct: 364 SPLGTV 369
>gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precursor
[Homo sapiens]
Length = 850
Score = 365 bits (937), Expect = e-100
Identities = 235/681 (34%), Positives = 356/681 (52%), Gaps = 54/681 (7%)
Query: 33 VLLVCVVF----HSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVY 88
++L+C+ F +GA++ +Y+I EE+ + +GN+ KDL L+ P + ++ +
Sbjct: 17 LVLLCLFFGIPWEAGARQISYSIPEELEKGSFVGNISKDLGLA--PRELAERGVR---IV 71
Query: 89 KTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRF 148
G L + +G + T G RIDRE+LCA R C V IL ++ +L I
Sbjct: 72 SRGRTQLFSLNPRSGSLITAG-RIDREELCAQSAR---CV--VSFNILVEDRVKLFGIEI 125
Query: 149 LIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGL 208
+ DINDNAP F A +++ I EN A ++ LP A+DPDVG+N +Q+Y+L +++ F L
Sbjct: 126 EVTDINDNAPKFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKH-FSL 184
Query: 209 DVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP 268
V G K P+L+++ LDREE+ + + + DGG P RS T ++ V+V D NDN P
Sbjct: 185 RVQSRANGVKYPELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAP 244
Query: 269 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 328
VF E VS+PEN PVGT + + ATD D G N ++ +SF L + F LN TG
Sbjct: 245 VFTLPEYRVSVPENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLLK-FQLNKYTG 303
Query: 329 LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT 388
I I E LD EET +++ + A DGG A A VL+ V DVNDN P + I + +PV
Sbjct: 304 EIKISENLDYEETGFYEIEIQAEDGGAYLATAKVLITVEDVNDNSPELTITSLFSPV--- 360
Query: 389 VVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYE 448
+E+ PL T +AL+ V D D++ NG+VTC +PF+L + + L LD E
Sbjct: 361 ---TEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDRE 417
Query: 449 STKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMK 508
Y I + A D G PPL+ A ++V D NDN P F+Q IPENN+ G +
Sbjct: 418 QVSSYNITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFS 477
Query: 509 VSATDADSGPNAEINYLLGPDA------PPEFSLDRRTGMLTVVKKLDREKEDKYLFTIL 562
V+A D DS NA+I Y L D S++ TG+L ++ D E+ + +
Sbjct: 478 VTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVT 537
Query: 563 AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGL---------- 612
A D+G PPL+SNV++ + ++DQNDN+P + LP G+ G+
Sbjct: 538 ASDSGDPPLSSNVSLSLFVLDQNDNAPEILY--------PALPTDGSTGVELAPRSAEPG 589
Query: 613 -----ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVK 665
+ D D G N+ ++ +L ++ F + TG +R + + V
Sbjct: 590 YLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVA 649
Query: 666 AEDGGRVSRSSSAKVTINVVD 686
+D G+ S++ +T+ V D
Sbjct: 650 VQDHGQPPLSATVTLTVAVAD 670
Score = 242 bits (618), Expect = 1e-63
Identities = 197/670 (29%), Positives = 312/670 (46%), Gaps = 71/670 (10%)
Query: 222 LIVQKELDREE------KDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEI 275
LI +DREE + + VED R +++ VTD NDN P F+ +
Sbjct: 88 LITAGRIDREELCAQSARCVVSFNILVED-----RVKLFGIEIEVTDINDNAPKFQAENL 142
Query: 276 EVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEP 335
+V I EN G A D D+G N+ + S + F L + +K P
Sbjct: 143 DVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLS------PNKHFSLRVQSRANGVKYP 196
Query: 336 -------LDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 386
LDREE H L++ ASDGG L +V V V D NDN P +
Sbjct: 197 ELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEY----- 251
Query: 387 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIP------FRLRPVFSNQFLLE 440
V + EN+P+ T++ +T TD+D NG VT ++ ++P F+L + E
Sbjct: 252 -RVSVPENLPVGTQLLTVTATDRDEGANGEVT-YSFRKLPDTQLLKFQLNKYTGEIKISE 309
Query: 441 NAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENN 500
N LDYE T Y I++ A D G +A + I V+D NDN+P T + + + E++
Sbjct: 310 N---LDYEETGFYEIEIQAEDGGA--YLATAKVLITVEDVNDNSPELTITSLFSPVTEDS 364
Query: 501 SPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGM---LTVVKKLDREKEDKY 557
G + ++ D DS N ++ + P F L++ L + + LDRE+ Y
Sbjct: 365 PLGTVVALLNVHDLDSEQNGQVTCSILAYLP--FKLEKSIDSYYRLVIHRALDREQVSSY 422
Query: 558 LFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTD 617
T+ A D G PPL++ + + D NDN P F+ Y Y+PEN R ++ +T D
Sbjct: 423 NITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALD 482
Query: 618 PDYGDNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG 670
PD +N+ + S+ ++ + +I+S TGV+ SFD E+ V A D G
Sbjct: 483 PDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSG 542
Query: 671 RVSRSSSAKVTINVVDVNDNKPVFIVPPY----NYSYELVLPSTNPGTVVFQVIAVDNDT 726
SS+ +++ V+D NDN P + P + EL S PG +V +V+AVD D+
Sbjct: 543 DPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDS 602
Query: 727 GMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSV 786
G NA + Y ++ + LFA+ + TG + D ++V D GQP L +
Sbjct: 603 GQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQP-PLSAT 661
Query: 787 VIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVV 846
V + + V +S+ ++ +L S E+P N+E +D++ Y+ + VAAV+
Sbjct: 662 VTLTVAVADSIPQ--VLADL--GSFESPA--NSETSDLTL----YLVVAVAAVSCVFLAF 711
Query: 847 VVIFITAVVR 856
V++ + +R
Sbjct: 712 VIVLLAHRLR 721
Score = 108 bits (270), Expect = 3e-23
Identities = 93/306 (30%), Positives = 137/306 (44%), Gaps = 30/306 (9%)
Query: 534 FSLDRRTGMLTVVKKLDREK------EDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDN 587
FSL+ R+G L ++DRE+ F IL +D + + + D NDN
Sbjct: 79 FSLNPRSGSLITAGRIDREELCAQSARCVVSFNILVEDR-----VKLFGIEIEVTDINDN 133
Query: 588 SPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQT---G 644
+P F + EN+ L DPD G NS + L N F++ Q+ G
Sbjct: 134 APKFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQ-LSPNKHFSLRVQSRANG 192
Query: 645 VIRPNI----SFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYN 700
V P + S DRE++ + + A DGG RS + V++ V D NDN PVF +P Y
Sbjct: 193 VKYPELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYR 252
Query: 701 YSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL--FAIDQETGNITLME 758
S LP GT + V A D D G N EV YS L F +++ TG I + E
Sbjct: 253 VSVPENLP---VGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLLKFQLNKYTGEIKISE 309
Query: 759 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPN 818
D + G + + ++A D G + V+I VN++ EL S+ +PVT +
Sbjct: 310 NLDYEETGFYEIEIQAEDGGAYLATAKVLITVEDVNDNSP------ELTITSLFSPVTED 363
Query: 819 TEIADV 824
+ + V
Sbjct: 364 SPLGTV 369
>gi|14589929 protocadherin 18 precursor [Homo sapiens]
Length = 1135
Score = 360 bits (924), Expect = 4e-99
Identities = 226/660 (34%), Positives = 360/660 (54%), Gaps = 27/660 (4%)
Query: 29 YIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLN--LSLIPNKSLTTTMQFKL 86
++FA+L+V + Y I EE +I L +D+ L +PN S T++F+
Sbjct: 12 FVFALLIVSFNHDVLGKNLKYRIYEEQRVGSVIARLSEDVADVLLKLPNPS---TVRFRA 68
Query: 87 VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKI 146
+ + G+ PL+ + ED GEI + GA IDRE+LC ++ +C E +V LP E +L I
Sbjct: 69 MQR-GNSPLLVVNEDNGEI-SIGATIDREQLCQ---KNLNCSIEFDVITLPTEHLQLFHI 123
Query: 147 RFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIF 206
+ DINDN+P F ++I I I E++A+ ++ L +A DPDVG N + Y L + + F
Sbjct: 124 EVEVLDINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSL-SANDFF 182
Query: 207 GLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDN 266
++V +G K +LIV +ELDRE K +Y +++ D G PQRS ++IL++S++D+NDN
Sbjct: 183 NIEVRTRTDGAKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDN 242
Query: 267 HPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNAT 326
P F++ + + EN+PVGT + L+ATD D G N KI +SFS+ VS F +++
Sbjct: 243 SPAFEQQSYIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSE 302
Query: 327 TGLITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNP 384
G +T+ + +D E T ++++ V A D G +PA +++ V DVNDN P I+I +
Sbjct: 303 RGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPG 362
Query: 385 VNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAY 444
+ + E P++T +AL+ V DKD+ NG + C F+L+ + N +L+ A
Sbjct: 363 KEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNAT 422
Query: 445 LDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGI 504
LD E EY++ ++A D G P L+ +++ D NDN P F +S I ENNSPG
Sbjct: 423 LDREKRSEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGA 482
Query: 505 QLMKVSATDADSGPNAEINY------LLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYL 558
+ V+ATD D G N ++ Y +LG ++D G + ++ D E+ +
Sbjct: 483 YITTVTATDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQIT 542
Query: 559 FTILAKDNGVP-PLTSNVTVFVSIIDQNDNSPV-----FTHNEYKFYVPENLPRHGTVGL 612
F + A+D G P L SN TV ++IID+NDN PV +N + +P+ V
Sbjct: 543 FVVEARDGGSPKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESGFHVTR 602
Query: 613 ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG 670
I D D G N+ ++ +I+ N++ F ID ++ I N+S D + V +D G
Sbjct: 603 IRAIDRDSGVNAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKG 662
Score = 234 bits (596), Expect = 4e-61
Identities = 188/628 (29%), Positives = 288/628 (45%), Gaps = 48/628 (7%)
Query: 256 LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFS-NLVS 314
++V V D NDN P F + I + I E+A VGT + A D D+GEN+ +S S N
Sbjct: 123 IEVEVLDINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFF 182
Query: 315 NIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARA---MVLVNVTDVND 371
NI R A + + LDRE +++L + ASD G+ P R+ ++ ++++D ND
Sbjct: 183 NIEVRTRTDGAKYAELIVVRELDRELKSSYELQLTASDMGV-PQRSGSSILKISISDSND 241
Query: 372 NVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVT-CFTDHEIPFRLR 430
N P+ + + + + L EN P+ T + + TD D NG++ F+ H P +
Sbjct: 242 NSPAFEQQSYI------IQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIME 295
Query: 431 P--VFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFT 488
+ S + L +DYE TK Y I + A D G + + IKV D NDN P
Sbjct: 296 TFKIDSERGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEIN 355
Query: 489 QSFVTVS------IPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGM 542
+ ++ I E + + V D DSG N EI L +
Sbjct: 356 INLMSPGKEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNY 415
Query: 543 LTVVKK-LDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVP 601
L + LDREK +Y T++A+D G P L++ V I D NDN P F + Y+F +
Sbjct: 416 LILTNATLDREKRSEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVIS 475
Query: 602 ENLPRHGTVGLITVTDPDYGDNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDR 654
EN + +T TDPD G+N VT +IL+ TID G I FD
Sbjct: 476 ENNSPGAYITTVTATDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDH 535
Query: 655 EKQESYTFYVKAEDGGRVSRS-SSAKVTINVVDVNDNKPVFIVPPY-NYSYELVLPS-TN 711
E+ TF V+A DGG + S+ V + ++D NDN PV I P N + E+ +P
Sbjct: 536 EEVSQITFVVEARDGGSPKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAE 595
Query: 712 PGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVL 771
G V ++ A+D D+G+NAE+ +IV GN ++F ID + +I D +
Sbjct: 596 SGFHVTRIRAIDRDSGVNAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELS 655
Query: 772 VKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDY 831
V D G P L + V++ + E + T +T + VS + D
Sbjct: 656 VIIQDKGNP-QLHTKVLLKCMIFEYAESVT----------------STAMTSVSQASLDV 698
Query: 832 VKILVAAVAGTITVVVVIFITAVVRCRQ 859
I++ ++ V++VI + RC +
Sbjct: 699 SMIIIISLGAICAVLLVIMVLFATRCNR 726
Score = 177 bits (450), Expect = 4e-44
Identities = 157/567 (27%), Positives = 238/567 (41%), Gaps = 48/567 (8%)
Query: 320 LFHLNATTGLITIKEPLDREETPNHKL-LVLASDGGLMPARAMVL----VNVTDVNDNVP 374
L +N G I+I +DRE+ L + D +P + L V V D+NDN P
Sbjct: 76 LLVVNEDNGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSP 135
Query: 375 SIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTD----HEIPFRLR 430
I + +SE+ + T+I L + D D N T I R R
Sbjct: 136 QFSRSLI------PIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTR 189
Query: 431 PVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQS 490
+ L LD E Y ++L A+D G P + S++L I + D NDN+P F Q
Sbjct: 190 TDGAKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQ 249
Query: 491 FVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPE----FSLDRRTGMLTVV 546
+ + EN+ G L+ ++ATD D G N +I Y P+ F +D G LT+
Sbjct: 250 SYIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKIDSERGHLTLF 309
Query: 547 KKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHN------EYKFYV 600
K++D E Y + A+D G + ++ + + ++D NDN P N E Y+
Sbjct: 310 KQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYI 369
Query: 601 PENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDS---QTGVIRPNISFDREKQ 657
E P V L+ V D D G N + L + F + +I N + DREK+
Sbjct: 370 FEGDPIDTFVALVRVQDKDSGLNGEIVCK-LHGHGHFKLQKTYENNYLILTNATLDREKR 428
Query: 658 ESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTN-PGTVV 716
Y+ V AED G S S+ T+ + D+NDN P F YE V+ N PG +
Sbjct: 429 SEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHF----QRSRYEFVISENNSPGAYI 484
Query: 717 FQVIAVDNDTGMNAEVRYS-----IVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVL 771
V A D D G N +V Y+ I+G + ID G I + D ++ +
Sbjct: 485 TTVTATDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQITFV 544
Query: 772 VKANDLGQPDSLFS-VVIVNLFVNESVTNATLINELVRKSIEAPVTPN--------TEIA 822
V+A D G P L S +V ++E+ +I +R + P T I
Sbjct: 545 VEARDGGSPKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESGFHVTRIR 604
Query: 823 DVSSPTSDYVKILVAAVAGTITVVVVI 849
+ + ++ A VAG + +I
Sbjct: 605 AIDRDSGVNAELSCAIVAGNEENIFII 631
>gi|157426847 protocadherin 19 isoform a [Homo sapiens]
Length = 1101
Score = 355 bits (911), Expect = 1e-97
Identities = 235/669 (35%), Positives = 362/669 (54%), Gaps = 36/669 (5%)
Query: 33 VLLVCVVFHSGAQEKN--YTIREEIPENVLIGNLLKDLN---LSLIPNKSLTTTMQFKLV 87
+LL+ +++ A N Y++ EE +I N+ KD +L P ++ F++V
Sbjct: 9 LLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASA----FRVV 64
Query: 88 YKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIR 147
+ L+ I +G + T +IDR+ LC P+ C +EV EI ++K+
Sbjct: 65 SNSAP-HLVDINPSSG-LLVTKQKIDRDLLCRQSPK---CIISLEVMSSSMEIC-VIKVE 118
Query: 148 FLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFG 207
I+D+NDNAP FPA I + I E ++ ++ L +A DPD G GVQ YEL ++ +FG
Sbjct: 119 --IKDLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNE-LFG 175
Query: 208 LDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNH 267
L++ +G + +L+V+K LDRE + Y ++ DGG P R T L + VTD+NDN+
Sbjct: 176 LEIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNN 235
Query: 268 PVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATT 327
PVF E+ VS+PEN+P T V +L+A+D D G N ++ +SF V++ R LF ++ +
Sbjct: 236 PVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHS 295
Query: 328 GLITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPV 385
GL+T+ LD EE ++L V A D G +PA V V+V D NDN P I+ +++
Sbjct: 296 GLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVIN---LLSVN 352
Query: 386 NDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYL 445
++ V +SE+ P IAL+ V+D+D+ NGRV C +PFRL+ S +L + L
Sbjct: 353 SELVEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGR-L 411
Query: 446 DYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQ 505
D E +Y + + A D G P L + + + DENDN P F++ + V + ENN+PG
Sbjct: 412 DREQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAY 471
Query: 506 LMKVSATDADSGPNAEINYLLGP----DAP--PEFSLDRRTGMLTVVKKLDREKEDKYLF 559
L+ VSA D D G N ++Y + P D P S++ +G + ++ + E+ + F
Sbjct: 472 LLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEF 531
Query: 560 TILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFT-----HNEYKFYVPENLPRHGTVGLIT 614
+LAKD G+P L SN TV V I+D NDN+PV T + + Y+P N V ++
Sbjct: 532 KVLAKDGGLPSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVK 591
Query: 615 VTDPDYGDNSAVTLSILD-ENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVS 673
D D G+N VT + + + F ID G +R +F + SY V A D G+ S
Sbjct: 592 AEDYDEGENGRVTYDMTEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTS 651
Query: 674 RSSSAKVTI 682
S+SA V I
Sbjct: 652 LSASALVLI 660
Score = 216 bits (551), Expect = 7e-56
Identities = 198/740 (26%), Positives = 320/740 (43%), Gaps = 70/740 (9%)
Query: 222 LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPE 281
L+ ++++DR+ K + +++V + D NDN P F +IE+ I E
Sbjct: 81 LVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLNDNAPSFPAAQIELEISE 140
Query: 282 NAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATT-------GLITIKE 334
A GT + A D D G + + LF L T + +++
Sbjct: 141 AASPGTRIPLDSAYDPDSGSFGVQTYELT------PNELFGLEIKTRGDGSRFAELVVEK 194
Query: 335 PLDREETPNHKLLVLASDGGLMPARAMV--LVNVTDVNDNVPSIDIRYIVNPVNDTVVLS 392
LDRE ++ + A DGG P V + VTD NDN P + + V +
Sbjct: 195 SLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNP------VFSESTYAVSVP 248
Query: 393 ENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLENAAYLDYES 449
EN P NT + + +D D NG+V + R R +F + L+ LDYE
Sbjct: 249 ENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEE 308
Query: 450 TKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVT---VSIPENNSPGIQL 506
Y + + A D G + + + V D NDN PV V V + E+ PG +
Sbjct: 309 GHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYVI 368
Query: 507 MKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDN 566
V +D DSG N + L + P + V +LDRE+ D+Y TI A+D
Sbjct: 369 ALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYNLTIQARDG 428
Query: 567 GVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAV 626
GVP L S + V I D+NDN P F+ Y+ V EN + ++ DPD G N +V
Sbjct: 429 GVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSV 488
Query: 627 TLSILDEN-------DDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAK 679
+ I+ +I+ +G I SF+ E+ +++ F V A+DGG S S+A
Sbjct: 489 SYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQSNAT 548
Query: 680 VTINVVDVNDNKPVFIVPP-YNYSYELVLP-STNPGTVVFQVIAVDNDTGMNAEVRYSIV 737
V + ++DVNDN PV PP N + E+ +P ++ G +V V A D D G N V Y +
Sbjct: 549 VRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRVTYDMT 608
Query: 738 GGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 797
G+ R F IDQ G + + + ++V A+D G+ SL + +V ++++ ++
Sbjct: 609 EGD-RGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGK-TSLSASALVLIYLSPAL 666
Query: 798 TNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRC 857
A S + + I + A+ ++ V I ++C
Sbjct: 667 D-----------------------AQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKC 703
Query: 858 RQAPHLKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDV 917
++ + + N + +E++ + KK KKKK S ++ L +EET +V
Sbjct: 704 KR-DNKEIRTYNCRIAEYSYGH--------QKKSSKKKKISKNDIRLVPRDVEETDKMNV 754
Query: 918 DSDGNRVTLDLPIDLEEQTM 937
S + + D +QT+
Sbjct: 755 VSCSSLTSSLNYFDYHQQTL 774
>gi|157426845 protocadherin 19 isoform b [Homo sapiens]
Length = 1100
Score = 355 bits (911), Expect = 1e-97
Identities = 235/669 (35%), Positives = 362/669 (54%), Gaps = 36/669 (5%)
Query: 33 VLLVCVVFHSGAQEKN--YTIREEIPENVLIGNLLKDLN---LSLIPNKSLTTTMQFKLV 87
+LL+ +++ A N Y++ EE +I N+ KD +L P ++ F++V
Sbjct: 9 LLLLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAREAGFALDPRQASA----FRVV 64
Query: 88 YKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIR 147
+ L+ I +G + T +IDR+ LC P+ C +EV EI ++K+
Sbjct: 65 SNSAP-HLVDINPSSG-LLVTKQKIDRDLLCRQSPK---CIISLEVMSSSMEIC-VIKVE 118
Query: 148 FLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFG 207
I+D+NDNAP FPA I + I E ++ ++ L +A DPD G GVQ YEL ++ +FG
Sbjct: 119 --IKDLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNE-LFG 175
Query: 208 LDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNH 267
L++ +G + +L+V+K LDRE + Y ++ DGG P R T L + VTD+NDN+
Sbjct: 176 LEIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNN 235
Query: 268 PVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATT 327
PVF E+ VS+PEN+P T V +L+A+D D G N ++ +SF V++ R LF ++ +
Sbjct: 236 PVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHS 295
Query: 328 GLITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPV 385
GL+T+ LD EE ++L V A D G +PA V V+V D NDN P I+ +++
Sbjct: 296 GLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVIN---LLSVN 352
Query: 386 NDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYL 445
++ V +SE+ P IAL+ V+D+D+ NGRV C +PFRL+ S +L + L
Sbjct: 353 SELVEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGR-L 411
Query: 446 DYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQ 505
D E +Y + + A D G P L + + + DENDN P F++ + V + ENN+PG
Sbjct: 412 DREQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAY 471
Query: 506 LMKVSATDADSGPNAEINYLLGP----DAP--PEFSLDRRTGMLTVVKKLDREKEDKYLF 559
L+ VSA D D G N ++Y + P D P S++ +G + ++ + E+ + F
Sbjct: 472 LLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEF 531
Query: 560 TILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFT-----HNEYKFYVPENLPRHGTVGLIT 614
+LAKD G+P L SN TV V I+D NDN+PV T + + Y+P N V ++
Sbjct: 532 KVLAKDGGLPSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVK 591
Query: 615 VTDPDYGDNSAVTLSILD-ENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVS 673
D D G+N VT + + + F ID G +R +F + SY V A D G+ S
Sbjct: 592 AEDYDEGENGRVTYDMTEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTS 651
Query: 674 RSSSAKVTI 682
S+SA V I
Sbjct: 652 LSASALVLI 660
Score = 216 bits (551), Expect = 7e-56
Identities = 198/740 (26%), Positives = 320/740 (43%), Gaps = 70/740 (9%)
Query: 222 LIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPE 281
L+ ++++DR+ K + +++V + D NDN P F +IE+ I E
Sbjct: 81 LVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLNDNAPSFPAAQIELEISE 140
Query: 282 NAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATT-------GLITIKE 334
A GT + A D D G + + LF L T + +++
Sbjct: 141 AASPGTRIPLDSAYDPDSGSFGVQTYELT------PNELFGLEIKTRGDGSRFAELVVEK 194
Query: 335 PLDREETPNHKLLVLASDGGLMPARAMV--LVNVTDVNDNVPSIDIRYIVNPVNDTVVLS 392
LDRE ++ + A DGG P V + VTD NDN P + + V +
Sbjct: 195 SLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNP------VFSESTYAVSVP 248
Query: 393 ENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLENAAYLDYES 449
EN P NT + + +D D NG+V + R R +F + L+ LDYE
Sbjct: 249 ENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYEE 308
Query: 450 TKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVT---VSIPENNSPGIQL 506
Y + + A D G + + + V D NDN PV V V + E+ PG +
Sbjct: 309 GHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYVI 368
Query: 507 MKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDN 566
V +D DSG N + L + P + V +LDRE+ D+Y TI A+D
Sbjct: 369 ALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRLDREQHDQYNLTIQARDG 428
Query: 567 GVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAV 626
GVP L S + V I D+NDN P F+ Y+ V EN + ++ DPD G N +V
Sbjct: 429 GVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSV 488
Query: 627 TLSILDEN-------DDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAK 679
+ I+ +I+ +G I SF+ E+ +++ F V A+DGG S S+A
Sbjct: 489 SYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQSNAT 548
Query: 680 VTINVVDVNDNKPVFIVPP-YNYSYELVLP-STNPGTVVFQVIAVDNDTGMNAEVRYSIV 737
V + ++DVNDN PV PP N + E+ +P ++ G +V V A D D G N V Y +
Sbjct: 549 VRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRVTYDMT 608
Query: 738 GGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 797
G+ R F IDQ G + + + ++V A+D G+ SL + +V ++++ ++
Sbjct: 609 EGD-RGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGK-TSLSASALVLIYLSPAL 666
Query: 798 TNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRC 857
A S + + I + A+ ++ V I ++C
Sbjct: 667 D-----------------------AQESMGSVNLSLIFIIALGSIAGILFVTMIFVAIKC 703
Query: 858 RQAPHLKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDV 917
++ + + N + +E++ + KK KKKK S ++ L +EET +V
Sbjct: 704 KR-DNKEIRTYNCRIAEYSYGH--------QKKSSKKKKISKNDIRLVPRDVEETDKMNV 754
Query: 918 DSDGNRVTLDLPIDLEEQTM 937
S + + D +QT+
Sbjct: 755 VSCSSLTSSLNYFDYHQQTL 774
>gi|94538350 protocadherin 17 precursor [Homo sapiens]
Length = 1159
Score = 355 bits (910), Expect = 2e-97
Identities = 241/699 (34%), Positives = 366/699 (52%), Gaps = 51/699 (7%)
Query: 48 NYTIREEIPENVLIGNLLKDLNLS--LIPNK----SLTTTMQFKLVYKTGDVPLIRIEED 101
NY++ EE +IGN+ +D L L P + + + ++++ + L+ ++ D
Sbjct: 22 NYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENSAP-HLLDVDAD 80
Query: 102 TGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFP 161
+G ++T RIDRE LC + C +EV EI ++K+ I+DINDNAP F
Sbjct: 81 SGLLYTK-QRIDRESLCR---HNAKCQLSLEVFANDKEIC-MIKVE--IQDINDNAPSFS 133
Query: 162 ATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQN-IFGLDVIETPEGDKMP 220
+ I + I EN+A +++ L +A DPD G NG++ Y L + + +FGLDV +G K P
Sbjct: 134 SDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDGTKFP 193
Query: 221 QLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIP 280
+L++QK LDRE+++ + + + DGG P RS+T + V V D+NDN PVF+ V +P
Sbjct: 194 ELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYLVELP 253
Query: 281 ENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREE 340
ENAP+GT V L+ATDAD G N ++ +SFS+ V + R LF ++ TGLI +K LD EE
Sbjct: 254 ENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGNLDYEE 313
Query: 341 TPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLN 398
++ V A D G +PA V V + D NDN PSI + LSE P
Sbjct: 314 NGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQG-----ALSEAAPPG 368
Query: 399 TKIALITVTDKDADHNGRVTCFT---------------DHEIPFRLRPVFSNQFLLENAA 443
T IAL+ VTD+D+ NG++ C +PF+L + N + +
Sbjct: 369 TVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDR 428
Query: 444 YLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPG 503
LD E+ EY + ++A D G PPLN + IK+ DENDN P FT+ + + ENN PG
Sbjct: 429 PLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPG 488
Query: 504 IQLMKVSATDADSGPNAEINYLLGPDAPPEFSL------DRRTGMLTVVKKLDREKEDKY 557
L V A D D G N ++Y + P + S+ + G + ++ + E+ +
Sbjct: 489 EYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAF 548
Query: 558 LFTILAKDNGVPP-LTSNVTVFVSIIDQNDNSPVFT-----HNEYKFYVPENLPRHGTVG 611
F +LAKD+G P L SN TV V+++D NDN+PV ++ + VP N V
Sbjct: 549 EFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQVPRNAGLGYLVS 608
Query: 612 LITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDG 669
+ D D+G++ +T I+D NDD F ID +G IR F + VK D
Sbjct: 609 TVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTDH 668
Query: 670 GRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLP 708
G+ + S+ AK+ I V + + V V + +++ LP
Sbjct: 669 GKPTLSAVAKLIIRSVSGSLPEGVPRVNGEQHHWDMSLP 707
Score = 253 bits (646), Expect = 7e-67
Identities = 234/816 (28%), Positives = 362/816 (44%), Gaps = 101/816 (12%)
Query: 157 APLFPATVINISIPENSAINS-----------KYTLPAAVDPDVGINGVQNYELIKSQNI 205
AP +N S+PE + + LP A G + +Y ++++
Sbjct: 13 APALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENSAP 72
Query: 206 FGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTND 265
LDV + G L ++ +DRE + K ++ F +++V + D ND
Sbjct: 73 HLLDV-DADSG----LLYTKQRIDRESLCRHNAKCQLSLEVFANDKEICMIKVEIQDIND 127
Query: 266 NHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNA 325
N P F +IE+ I ENA GT A D D GEN + L++ LF L+
Sbjct: 128 NAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTY----LLTRDDHGLFGLDV 183
Query: 326 TTG-------LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVT--DVNDNVPSI 376
+ + I++ LDRE+ +H L++ A DGG P A V +NV D NDN P
Sbjct: 184 KSRGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVF 243
Query: 377 DI-RYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS- 434
+ Y+V L EN PL T + + TD D NG V +P R+R +FS
Sbjct: 244 EAPSYLVE-------LPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSI 296
Query: 435 --NQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFV 492
L+ LDYE I + A D G P+ + +K+ D NDNAP FV
Sbjct: 297 DPKTGLIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSI--GFV 354
Query: 493 TV---SIPENNSPGIQLMKVSATDADSGPNAEINY-------------LLGPDAPPEFSL 536
+V ++ E PG + V TD DSG N ++ L GP F L
Sbjct: 355 SVRQGALSEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKL 414
Query: 537 DRR-TGMLTVV--KKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTH 593
+ TVV + LDRE +D+Y TI+A+D G PPL S + + I+D+NDN P FT
Sbjct: 415 EENYDNFYTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTK 474
Query: 594 NEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDD-------FTIDSQTGVI 646
Y V EN +G + DPD G N V+ SIL + +++ G I
Sbjct: 475 GLYVLQVHENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAI 534
Query: 647 RPNISFDREKQESYTFYVKAEDGGRVSR-SSSAKVTINVVDVNDNKPVFIVPPY-NYSYE 704
SF+ E+ +++ F V A+D G + S+A V + V+DVNDN PV ++P N + E
Sbjct: 535 YALRSFNFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAE 594
Query: 705 LVLP-STNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKC--D 761
L +P + G +V V A+D+D G + + Y IV GN LF ID +G I + D
Sbjct: 595 LQVPRNAGLGYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWED 654
Query: 762 VTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEI 821
VT + ++VK D G+P + + +L+ +S+ +
Sbjct: 655 VTP--VVELVVKVTDHGKP------------------TLSAVAKLIIRSVSGSLPEGVPR 694
Query: 822 ADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPE 881
+ D L+ ++ +++ IT V+C++ + + N + +E++ P
Sbjct: 695 VNGEQHHWDMSLPLIVTLSTISIILLAAMITIAVKCKR-ENKEIRTYNCRIAEYSHPQ-- 751
Query: 882 NRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDV 917
+ K KKKK + +++L +EE A +V
Sbjct: 752 -----LGGGKGKKKKINKNDIMLVQSEVEERNAMNV 782
>gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 352 bits (904), Expect = 8e-97
Identities = 219/676 (32%), Positives = 352/676 (52%), Gaps = 50/676 (7%)
Query: 34 LLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDV 93
+L+ ++ +G + Y++ EE+ + +G++ +DL L P + ++ + G
Sbjct: 18 ILLGTLWETGCTQIRYSVPEELEKGSRVGDISRDLGLE--PRELAERGVR---IIPRGRT 72
Query: 94 PLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDI 153
L + +G + T G RIDRE+LC G + ++ + IL ++ ++ + + DI
Sbjct: 73 QLFALNPRSGSLVTAG-RIDREELCMGAIK-----CQLNLDILMEDKVKIYGVEVEVRDI 126
Query: 154 NDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIET 213
NDNAP F + + I I EN+A ++ LP A DPD+G N +Q+YEL + + F L V
Sbjct: 127 NDNAPYFRESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTH-FSLIVQNG 185
Query: 214 PEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKET 273
+G K P+L++++ LDREEK + + + DGG P R+ TA ++V V D NDN P F +
Sbjct: 186 ADGSKYPELVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQP 245
Query: 274 EIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK 333
E S+PEN +GT + ++ATD D G NA++ +SF V + A ++F L+ +G I+
Sbjct: 246 EYRASVPENLALGTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNSGTISTI 304
Query: 334 EPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSE 393
LD EE+ +++ V A D ARA VL+ V DVNDN P + + + + V E
Sbjct: 305 GELDHEESGFYQMEVQAMDNAGYSARAKVLITVLDVNDNAPEVVLTSLASSV------PE 358
Query: 394 NIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEY 453
N P T IAL+ V D+D++ NG+V CF +PF+L + N + L LD E Y
Sbjct: 359 NSPRGTLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSY 418
Query: 454 AIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATD 513
I + A D G PPL+ + + V D NDN PVF Q+ + IPENN G+ L+ V+A D
Sbjct: 419 NITVTATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHD 478
Query: 514 ADSGPNAEINYLL------GPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNG 567
D NA+I Y L G S++ TG+L + D E+ ++A+DNG
Sbjct: 479 PDCEENAQITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNG 538
Query: 568 VPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGL--------------- 612
PPL+SNV++ + ++DQNDN+P + LP G+ G+
Sbjct: 539 HPPLSSNVSLSLFVLDQNDNAPEILY--------PALPTDGSTGVELAPRSAEPGYLVTK 590
Query: 613 ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG 670
+ D D G N+ ++ +L ++ F++ TG +R + + V +D G
Sbjct: 591 VVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHG 650
Query: 671 RVSRSSSAKVTINVVD 686
+ S++ +T+ V D
Sbjct: 651 QPPLSATVTLTVAVAD 666
Score = 247 bits (631), Expect = 4e-65
Identities = 196/659 (29%), Positives = 311/659 (47%), Gaps = 49/659 (7%)
Query: 222 LIVQKELDREEKDTYVMKVKVE-DGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIP 280
L+ +DREE +K ++ D + ++V V D NDN P F+E+E+E+ I
Sbjct: 84 LVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNAPYFRESELEIKIS 143
Query: 281 ENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGL----ITIKEPL 336
ENA HA D DIG+N+ + S N L N G + +K L
Sbjct: 144 ENAATEMRFPLPHAWDPDIGKNSLQSYELS---PNTHFSLIVQNGADGSKYPELVLKRAL 200
Query: 337 DREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSEN 394
DREE H L++ ASDGG + A + V V D NDN P+ P V EN
Sbjct: 201 DREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAF-----AQPEYRASV-PEN 254
Query: 395 IPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLENAAYLDYESTK 451
+ L T++ ++ TD D N V ++ + + VF N + LD+E +
Sbjct: 255 LALGTQLLVVNATDPDEGVNAEVR-YSFRYVDDKAAQVFKLDCNSGTISTIGELDHEESG 313
Query: 452 EYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSA 511
Y +++ A D + A + I V D NDNAP + + S+PEN+ G + ++
Sbjct: 314 FYQMEVQAMD--NAGYSARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRGTLIALLNV 371
Query: 512 TDADSGPNAEINYLLGPDAPPEFSLDRRTG---MLTVVKKLDREKEDKYLFTILAKDNGV 568
D DS N ++ + + P F L++ G L LDRE+ Y T+ A D G
Sbjct: 372 NDQDSEENGQVICFIQGNLP--FKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGT 429
Query: 569 PPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTL 628
PPL++ + +++ D NDN PVF Y Y+PEN PR ++ +T DPD +N+ +T
Sbjct: 430 PPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQITY 489
Query: 629 SILDE-------NDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 681
S+ + + +I+S TGV+ SFD E+ V A D G SS+ ++
Sbjct: 490 SLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNVSLS 549
Query: 682 INVVDVNDNKPVFIVPPY----NYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIV 737
+ V+D NDN P + P + EL S PG +V +V+AVD D+G NA + Y ++
Sbjct: 550 LFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLL 609
Query: 738 GGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 797
+ LF++ TG + D ++V D GQP L + V + + V +S+
Sbjct: 610 KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQP-PLSATVTLTVAVADSI 668
Query: 798 TNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR 856
++ +L S+E+P N+E +D++ Y+ + VAAV+ V++ + +R
Sbjct: 669 PQ--VLADL--GSLESPA--NSETSDLTL----YLVVAVAAVSCVFLAFVILLLALRLR 717
>gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 352 bits (904), Expect = 8e-97
Identities = 219/676 (32%), Positives = 352/676 (52%), Gaps = 50/676 (7%)
Query: 34 LLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDV 93
+L+ ++ +G + Y++ EE+ + +G++ +DL L P + ++ + G
Sbjct: 18 ILLGTLWETGCTQIRYSVPEELEKGSRVGDISRDLGLE--PRELAERGVR---IIPRGRT 72
Query: 94 PLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDI 153
L + +G + T G RIDRE+LC G + ++ + IL ++ ++ + + DI
Sbjct: 73 QLFALNPRSGSLVTAG-RIDREELCMGAIK-----CQLNLDILMEDKVKIYGVEVEVRDI 126
Query: 154 NDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIET 213
NDNAP F + + I I EN+A ++ LP A DPD+G N +Q+YEL + + F L V
Sbjct: 127 NDNAPYFRESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTH-FSLIVQNG 185
Query: 214 PEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKET 273
+G K P+L++++ LDREEK + + + DGG P R+ TA ++V V D NDN P F +
Sbjct: 186 ADGSKYPELVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQP 245
Query: 274 EIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIK 333
E S+PEN +GT + ++ATD D G NA++ +SF V + A ++F L+ +G I+
Sbjct: 246 EYRASVPENLALGTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNSGTISTI 304
Query: 334 EPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSE 393
LD EE+ +++ V A D ARA VL+ V DVNDN P + + + + V E
Sbjct: 305 GELDHEESGFYQMEVQAMDNAGYSARAKVLITVLDVNDNAPEVVLTSLASSV------PE 358
Query: 394 NIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEY 453
N P T IAL+ V D+D++ NG+V CF +PF+L + N + L LD E Y
Sbjct: 359 NSPRGTLIALLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSY 418
Query: 454 AIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATD 513
I + A D G PPL+ + + V D NDN PVF Q+ + IPENN G+ L+ V+A D
Sbjct: 419 NITVTATDRGTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHD 478
Query: 514 ADSGPNAEINYLL------GPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNG 567
D NA+I Y L G S++ TG+L + D E+ ++A+DNG
Sbjct: 479 PDCEENAQITYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNG 538
Query: 568 VPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGL--------------- 612
PPL+SNV++ + ++DQNDN+P + LP G+ G+
Sbjct: 539 HPPLSSNVSLSLFVLDQNDNAPEILY--------PALPTDGSTGVELAPRSAEPGYLVTK 590
Query: 613 ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG 670
+ D D G N+ ++ +L ++ F++ TG +R + + V +D G
Sbjct: 591 VVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHG 650
Query: 671 RVSRSSSAKVTINVVD 686
+ S++ +T+ V D
Sbjct: 651 QPPLSATVTLTVAVAD 666
Score = 247 bits (631), Expect = 4e-65
Identities = 196/659 (29%), Positives = 311/659 (47%), Gaps = 49/659 (7%)
Query: 222 LIVQKELDREEKDTYVMKVKVE-DGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIP 280
L+ +DREE +K ++ D + ++V V D NDN P F+E+E+E+ I
Sbjct: 84 LVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNAPYFRESELEIKIS 143
Query: 281 ENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGL----ITIKEPL 336
ENA HA D DIG+N+ + S N L N G + +K L
Sbjct: 144 ENAATEMRFPLPHAWDPDIGKNSLQSYELS---PNTHFSLIVQNGADGSKYPELVLKRAL 200
Query: 337 DREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSEN 394
DREE H L++ ASDGG + A + V V D NDN P+ P V EN
Sbjct: 201 DREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAF-----AQPEYRASV-PEN 254
Query: 395 IPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLENAAYLDYESTK 451
+ L T++ ++ TD D N V ++ + + VF N + LD+E +
Sbjct: 255 LALGTQLLVVNATDPDEGVNAEVR-YSFRYVDDKAAQVFKLDCNSGTISTIGELDHEESG 313
Query: 452 EYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSA 511
Y +++ A D + A + I V D NDNAP + + S+PEN+ G + ++
Sbjct: 314 FYQMEVQAMD--NAGYSARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRGTLIALLNV 371
Query: 512 TDADSGPNAEINYLLGPDAPPEFSLDRRTG---MLTVVKKLDREKEDKYLFTILAKDNGV 568
D DS N ++ + + P F L++ G L LDRE+ Y T+ A D G
Sbjct: 372 NDQDSEENGQVICFIQGNLP--FKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGT 429
Query: 569 PPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTL 628
PPL++ + +++ D NDN PVF Y Y+PEN PR ++ +T DPD +N+ +T
Sbjct: 430 PPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQITY 489
Query: 629 SILDE-------NDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVT 681
S+ + + +I+S TGV+ SFD E+ V A D G SS+ ++
Sbjct: 490 SLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNVSLS 549
Query: 682 INVVDVNDNKPVFIVPPY----NYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIV 737
+ V+D NDN P + P + EL S PG +V +V+AVD D+G NA + Y ++
Sbjct: 550 LFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLL 609
Query: 738 GGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 797
+ LF++ TG + D ++V D GQP L + V + + V +S+
Sbjct: 610 KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQP-PLSATVTLTVAVADSI 668
Query: 798 TNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVVR 856
++ +L S+E+P N+E +D++ Y+ + VAAV+ V++ + +R
Sbjct: 669 PQ--VLADL--GSLESPA--NSETSDLTL----YLVVAVAAVSCVFLAFVILLLALRLR 717
>gi|14270490 protocadherin gamma subfamily B, 1 isoform 2 precursor
[Homo sapiens]
Length = 810
Score = 349 bits (895), Expect = 9e-96
Identities = 231/664 (34%), Positives = 346/664 (52%), Gaps = 50/664 (7%)
Query: 44 AQEKNYTIREEIPENVLIGNLLKDLNLSL--IPNKSLTTTMQFKLVYKTGDVPLIRIEED 101
+Q+ YTI EE+ +G L KDL LS+ +P + L + + + +
Sbjct: 28 SQQIRYTIPEELANGSRVGKLAKDLGLSVRELPTRKLRVSAE----------DYFNVSLE 77
Query: 102 TGEIFTTGARIDREKLCAGIPRDEHCFYEVE-VAILPDEIFRLVKIRFLIEDINDNAPLF 160
+G++ G RIDREK+C R C E E VA P +F +V + I+DINDNAP F
Sbjct: 78 SGDLLVNG-RIDREKICG---RKLECALEFETVAENPMNVFHVVVV---IQDINDNAPRF 130
Query: 161 PATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMP 220
A I++ I E++ K++L +A D DV N ++ Y + +Q F L E+P+G K P
Sbjct: 131 VAKGIDLEICESALPGVKFSLDSAQDADVEGNSLKLYTINPNQ-YFSLSTKESPDGSKYP 189
Query: 221 QLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIP 280
L+++K LDRE + ++ + + DGG P S T + + VTD NDN PVF + VS+
Sbjct: 190 VLLLEKPLDREHQSSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAPVFSQEVYRVSLQ 249
Query: 281 ENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREE 340
EN P GTSV ++ ATD D G NA+I ++F N S I+ LF+LN TG IT LD EE
Sbjct: 250 ENVPWGTSVLRVMATDQDEGINAEITYAFLN--SPISTSLFNLNPNTGDITTNGTLDFEE 307
Query: 341 TPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTK 400
T + L V A DGG+ A V + + D NDN P + N + E+ L T
Sbjct: 308 TSRYVLSVEAKDGGVHTAHCNVQIEIVDENDNAPEVTFMSFSNQI------PEDSDLGTV 361
Query: 401 IALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAA 460
IALI V DKD+ NG VTC+T E+PF+L N + L A L+ E T +Y + ++A
Sbjct: 362 IALIKVRDKDSGQNGMVTCYTQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIAT 421
Query: 461 DAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNA 520
D GKP L+ + + + D NDNAPVF Q+ V + ENN PG + +VSA+D D GPN
Sbjct: 422 DKGKPALSSRTSITLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNG 481
Query: 521 EINY-LLGPDAPPE-----FSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSN 574
++Y +L D P S+ ++G++ + D E+ + T+ A+D G P L++N
Sbjct: 482 RVSYSILASDLEPRELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSAN 541
Query: 575 VTVFVSIIDQNDNSPVFTHNEYKFYVPEN------LPRHGTVGL----ITVTDPDYGDNS 624
V++ V + D NDN+P Y P+ +PR G + D D G N+
Sbjct: 542 VSLRVLVGDLNDNAPRVL---YPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNA 598
Query: 625 AVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTI 682
++ +L ++ F++ +TG +R + V DGG+ S++A + +
Sbjct: 599 WLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHL 658
Query: 683 NVVD 686
D
Sbjct: 659 IFAD 662
Score = 234 bits (596), Expect = 4e-61
Identities = 188/709 (26%), Positives = 328/709 (46%), Gaps = 53/709 (7%)
Query: 165 INISIPENSAINSKYTLPAAVDPDVGINGVQNYEL-IKSQNIFGLDVIETPEGDKMPQLI 223
I +IPE A S+ A D + + + +L + +++ F + + GD L+
Sbjct: 31 IRYTIPEELANGSRVG-KLAKDLGLSVRELPTRKLRVSAEDYFNVSL---ESGD----LL 82
Query: 224 VQKELDREEKDTYVMKVKVEDGGFPQRSSTAI-LQVSVTDTNDNHPVFKETEIEVSIPEN 282
V +DRE+ ++ +E + + V + D NDN P F I++ I E+
Sbjct: 83 VNGRIDREKICGRKLECALEFETVAENPMNVFHVVVVIQDINDNAPRFVAKGIDLEICES 142
Query: 283 APVGTSVTQLHATDADI-GENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREET 341
A G + A DAD+ G + K++ N +++ + + ++ +++PLDRE
Sbjct: 143 ALPGVKFSLDSAQDADVEGNSLKLYTINPNQYFSLSTKESPDGSKYPVLLLEKPLDREHQ 202
Query: 342 PNHKLLVLASDGGLMPARAM--VLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNT 399
+H+L++ A DGG P + + VTD NDN P + + V L EN+P T
Sbjct: 203 SSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAP------VFSQEVYRVSLQENVPWGT 256
Query: 400 KIALITVTDKDADHNGRVT-CFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLL 458
+ + TD+D N +T F + I L + N + LD+E T Y + +
Sbjct: 257 SVLRVMATDQDEGINAEITYAFLNSPISTSLFNLNPNTGDITTNGTLDFEETSRYVLSVE 316
Query: 459 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGP 518
A D G + + I++ DENDNAP T + IPE++ G + + D DSG
Sbjct: 317 AKDGGVHTAHCNVQ--IEIVDENDNAPEVTFMSFSNQIPEDSDLGTVIALIKVRDKDSGQ 374
Query: 519 NAEINYLLGPDAPPEF-SLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTV 577
N + + P + S + L + L+RE+ Y TI+A D G P L+S ++
Sbjct: 375 NGMVTCYTQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIATDKGKPALSSRTSI 434
Query: 578 FVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDD- 636
+ I D NDN+PVF Y +V EN P ++ ++ +DPD G N V+ SIL + +
Sbjct: 435 TLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNGRVSYSILASDLEP 494
Query: 637 ------FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDN 690
++ Q+GV+ +FD E+ ++ ++A D G + S++ + + V D+NDN
Sbjct: 495 RELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGDLNDN 554
Query: 691 KPVFIVPPYNYS----YELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFA 746
P + P +++V + PG +V +V+AVD D+G NA + Y ++ + LF+
Sbjct: 555 APRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFS 614
Query: 747 IDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINEL 806
+ TG + D R+LV D GQP + + +F +
Sbjct: 615 LGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFAD------------ 662
Query: 807 VRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVV 855
S++ + ++ + S P ++ LV A+A ++ V+F+ AV+
Sbjct: 663 ---SLQEVLPDLSDRPEPSDPQTELQFYLVVALA----LISVLFLLAVI 704
>gi|11128037 protocadherin gamma subfamily B, 1 isoform 1 precursor
[Homo sapiens]
Length = 927
Score = 349 bits (895), Expect = 9e-96
Identities = 231/664 (34%), Positives = 346/664 (52%), Gaps = 50/664 (7%)
Query: 44 AQEKNYTIREEIPENVLIGNLLKDLNLSL--IPNKSLTTTMQFKLVYKTGDVPLIRIEED 101
+Q+ YTI EE+ +G L KDL LS+ +P + L + + + +
Sbjct: 28 SQQIRYTIPEELANGSRVGKLAKDLGLSVRELPTRKLRVSAE----------DYFNVSLE 77
Query: 102 TGEIFTTGARIDREKLCAGIPRDEHCFYEVE-VAILPDEIFRLVKIRFLIEDINDNAPLF 160
+G++ G RIDREK+C R C E E VA P +F +V + I+DINDNAP F
Sbjct: 78 SGDLLVNG-RIDREKICG---RKLECALEFETVAENPMNVFHVVVV---IQDINDNAPRF 130
Query: 161 PATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMP 220
A I++ I E++ K++L +A D DV N ++ Y + +Q F L E+P+G K P
Sbjct: 131 VAKGIDLEICESALPGVKFSLDSAQDADVEGNSLKLYTINPNQ-YFSLSTKESPDGSKYP 189
Query: 221 QLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIP 280
L+++K LDRE + ++ + + DGG P S T + + VTD NDN PVF + VS+
Sbjct: 190 VLLLEKPLDREHQSSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAPVFSQEVYRVSLQ 249
Query: 281 ENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREE 340
EN P GTSV ++ ATD D G NA+I ++F N S I+ LF+LN TG IT LD EE
Sbjct: 250 ENVPWGTSVLRVMATDQDEGINAEITYAFLN--SPISTSLFNLNPNTGDITTNGTLDFEE 307
Query: 341 TPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTK 400
T + L V A DGG+ A V + + D NDN P + N + E+ L T
Sbjct: 308 TSRYVLSVEAKDGGVHTAHCNVQIEIVDENDNAPEVTFMSFSNQI------PEDSDLGTV 361
Query: 401 IALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAA 460
IALI V DKD+ NG VTC+T E+PF+L N + L A L+ E T +Y + ++A
Sbjct: 362 IALIKVRDKDSGQNGMVTCYTQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIAT 421
Query: 461 DAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNA 520
D GKP L+ + + + D NDNAPVF Q+ V + ENN PG + +VSA+D D GPN
Sbjct: 422 DKGKPALSSRTSITLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNG 481
Query: 521 EINY-LLGPDAPPE-----FSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSN 574
++Y +L D P S+ ++G++ + D E+ + T+ A+D G P L++N
Sbjct: 482 RVSYSILASDLEPRELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSAN 541
Query: 575 VTVFVSIIDQNDNSPVFTHNEYKFYVPEN------LPRHGTVGL----ITVTDPDYGDNS 624
V++ V + D NDN+P Y P+ +PR G + D D G N+
Sbjct: 542 VSLRVLVGDLNDNAPRVL---YPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNA 598
Query: 625 AVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTI 682
++ +L ++ F++ +TG +R + V DGG+ S++A + +
Sbjct: 599 WLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHL 658
Query: 683 NVVD 686
D
Sbjct: 659 IFAD 662
Score = 234 bits (596), Expect = 4e-61
Identities = 188/709 (26%), Positives = 328/709 (46%), Gaps = 53/709 (7%)
Query: 165 INISIPENSAINSKYTLPAAVDPDVGINGVQNYEL-IKSQNIFGLDVIETPEGDKMPQLI 223
I +IPE A S+ A D + + + +L + +++ F + + GD L+
Sbjct: 31 IRYTIPEELANGSRVG-KLAKDLGLSVRELPTRKLRVSAEDYFNVSL---ESGD----LL 82
Query: 224 VQKELDREEKDTYVMKVKVEDGGFPQRSSTAI-LQVSVTDTNDNHPVFKETEIEVSIPEN 282
V +DRE+ ++ +E + + V + D NDN P F I++ I E+
Sbjct: 83 VNGRIDREKICGRKLECALEFETVAENPMNVFHVVVVIQDINDNAPRFVAKGIDLEICES 142
Query: 283 APVGTSVTQLHATDADI-GENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREET 341
A G + A DAD+ G + K++ N +++ + + ++ +++PLDRE
Sbjct: 143 ALPGVKFSLDSAQDADVEGNSLKLYTINPNQYFSLSTKESPDGSKYPVLLLEKPLDREHQ 202
Query: 342 PNHKLLVLASDGGLMPARAM--VLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNT 399
+H+L++ A DGG P + + VTD NDN P + + V L EN+P T
Sbjct: 203 SSHRLILTAMDGGDPPLSGTTHIWIRVTDANDNAP------VFSQEVYRVSLQENVPWGT 256
Query: 400 KIALITVTDKDADHNGRVT-CFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLL 458
+ + TD+D N +T F + I L + N + LD+E T Y + +
Sbjct: 257 SVLRVMATDQDEGINAEITYAFLNSPISTSLFNLNPNTGDITTNGTLDFEETSRYVLSVE 316
Query: 459 AADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGP 518
A D G + + I++ DENDNAP T + IPE++ G + + D DSG
Sbjct: 317 AKDGGVHTAHCNVQ--IEIVDENDNAPEVTFMSFSNQIPEDSDLGTVIALIKVRDKDSGQ 374
Query: 519 NAEINYLLGPDAPPEF-SLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTV 577
N + + P + S + L + L+RE+ Y TI+A D G P L+S ++
Sbjct: 375 NGMVTCYTQEEVPFKLESTSKNYYKLVIAGALNREQTADYNVTIIATDKGKPALSSRTSI 434
Query: 578 FVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDD- 636
+ I D NDN+PVF Y +V EN P ++ ++ +DPD G N V+ SIL + +
Sbjct: 435 TLHISDINDNAPVFHQASYVVHVSENNPPGASIAQVSASDPDLGPNGRVSYSILASDLEP 494
Query: 637 ------FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDN 690
++ Q+GV+ +FD E+ ++ ++A D G + S++ + + V D+NDN
Sbjct: 495 RELLSYVSVSPQSGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVGDLNDN 554
Query: 691 KPVFIVPPYNYS----YELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFA 746
P + P +++V + PG +V +V+AVD D+G NA + Y ++ + LF+
Sbjct: 555 APRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFS 614
Query: 747 IDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINEL 806
+ TG + D R+LV D GQP + + +F +
Sbjct: 615 LGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLIFAD------------ 662
Query: 807 VRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVVIFITAVV 855
S++ + ++ + S P ++ LV A+A ++ V+F+ AV+
Sbjct: 663 ---SLQEVLPDLSDRPEPSDPQTELQFYLVVALA----LISVLFLLAVI 704
>gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]
Length = 1040
Score = 348 bits (892), Expect = 2e-95
Identities = 226/678 (33%), Positives = 352/678 (51%), Gaps = 57/678 (8%)
Query: 48 NYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFT 107
+YT++EE +GN+ +DL L + + + F+ V P + + +TG ++
Sbjct: 21 HYTVQEEQEHGTFVGNIAEDLGLDI----TKLSARGFQTV-PNSRTPYLDLNLETGVLYV 75
Query: 108 TGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINI 167
+IDRE++C P C +EV + + L ++ + DINDN P FP + +
Sbjct: 76 N-EKIDREQICKQSPS---CVLHLEVFL--ENPLELFQVEIEVLDINDNPPSFPEPDLTV 129
Query: 168 SIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKE 227
I E++ +++ L +A DPDVG N +++YE I + F LDV +G++ +L+++K
Sbjct: 130 EISESATPGTRFPLESAFDPDVGTNSLRDYE-ITPNSYFSLDVQTQGDGNRFAELVLEKP 188
Query: 228 LDREEKDTYVMKVKVEDGGF-------------------PQRSSTAILQVSVTDTNDNHP 268
LDRE++ + + DGG QR+ TA+L + V D+NDN P
Sbjct: 189 LDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVP 248
Query: 269 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 328
F + VS+PEN+P GT V QL+ATD D G+N ++ +SFS+ +S AR LF L+ TG
Sbjct: 249 AFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTG 308
Query: 329 LITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 386
+ + LD EE+P +++ V A D G +PA VLV V D NDN P I + V
Sbjct: 309 RLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAV- 367
Query: 387 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLD 446
SE T +AL +VTD+D++ NG+V C ++PFRL+ F N + + A LD
Sbjct: 368 -----SEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLD 422
Query: 447 YESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQL 506
E+ Y + ++A D G+P L+ S + ++V D NDNAP F+Q V + ENN PG +
Sbjct: 423 REAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYI 482
Query: 507 MKVSATDADSGPNAEINY------LLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFT 560
VSATD D G NA++ Y + G S++ G L ++ D E+ + F
Sbjct: 483 YAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQ 542
Query: 561 ILAKDNGVP-PLTSNVTVFVSIIDQNDNSPVFT---HNEYKFYVPENLPRHGTVGL---- 612
+ A+D G P L N TV + I+DQNDN+P E LPR G
Sbjct: 543 VEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTR 602
Query: 613 ITVTDPDYGDNSAVTLSIL--DENDDFTIDSQTGVIRP--NISFDREKQESYTFYVKAED 668
+ D D G+N+ +T SI+ +E + F +D +TG +R + R+ Q Y ++ D
Sbjct: 603 VAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRD 662
Query: 669 GGRVSRSSSAKVTINVVD 686
G+ SS+A + + +VD
Sbjct: 663 HGQPPLSSTATLVVQLVD 680
Score = 233 bits (593), Expect = 9e-61
Identities = 178/588 (30%), Positives = 272/588 (46%), Gaps = 58/588 (9%)
Query: 256 LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSN 315
+++ V D NDN P F E ++ V I E+A GT A D D+G N+ + +
Sbjct: 108 VEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEIT----- 162
Query: 316 IARRLFHLNATT-------GLITIKEPLDREETPNHKLLVLASDGG-------------- 354
F L+ T + +++PLDRE+ H+ ++ A DGG
Sbjct: 163 -PNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGG 221
Query: 355 --LMPAR-----AMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVT 407
L P + A++ + V D NDNVP+ D PV TV L EN P T + + T
Sbjct: 222 AGLPPQQQRTGTALLTIRVLDSNDNVPAFD-----QPVY-TVSLPENSPPGTLVIQLNAT 275
Query: 408 DKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLENAAYLDYESTKEYAIKLLAADAGK 464
D D NG V I R R +F LE + LDYE + Y + + A D G
Sbjct: 276 DPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGP 335
Query: 465 PPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINY 524
+ + ++V D NDNAP + S V ++ E +PG + S TD DS N ++
Sbjct: 336 NAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQC 395
Query: 525 LLGPDAPPEFSLDRRTGMLTVVKK-LDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIID 583
L D P + V + LDRE D Y T++A+D G P L+++ ++ V + D
Sbjct: 396 ELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSD 455
Query: 584 QNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDD------- 636
NDN+P F+ Y YV EN + ++ TD D G N+ + SIL+
Sbjct: 456 VNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTY 515
Query: 637 FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSR-SSSAKVTINVVDVNDNKPVFI 695
+I+S+ G + SFD E+ + ++F V+A D G + +A V I +VD NDN P +
Sbjct: 516 VSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIV 575
Query: 696 VPPYNYS----YELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQET 751
P + E++ S PG ++ +V AVD D G NA + YSIV GN +LF +D T
Sbjct: 576 APLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRT 635
Query: 752 GNITLMEKCDV--TDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 797
G + + + ++++ D GQP + +V V+ +V
Sbjct: 636 GELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAV 683
Score = 190 bits (482), Expect = 7e-48
Identities = 178/583 (30%), Positives = 256/583 (43%), Gaps = 78/583 (13%)
Query: 273 TEIEVSIPENAPVGTSVTQLHATDADIG-ENAKIHFSFSNLVSNIARRLFHLNATTGLIT 331
+++ ++ E GT V + D+G + K+ V N LN TG++
Sbjct: 18 SQLHYTVQEEQEHGTFVGNIAE---DLGLDITKLSARGFQTVPNSRTPYLDLNLETGVLY 74
Query: 332 IKEPLDREE----TPN---HKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNP 384
+ E +DRE+ +P+ H + L + L V + V D+NDN PS P
Sbjct: 75 VNEKIDREQICKQSPSCVLHLEVFLENPLELF----QVEIEVLDINDNPPSF-------P 123
Query: 385 VND-TVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS--------- 434
D TV +SE+ T+ L + D D N D+EI FS
Sbjct: 124 EPDLTVEISESATPGTRFPLESAFDPDVGTNS----LRDYEIT--PNSYFSLDVQTQGDG 177
Query: 435 NQF---LLENAAYLDYESTKEYAIKLLAAD----------------AGKPPLNQ---SAM 472
N+F +LE LD E + L A D AG PP Q +A+
Sbjct: 178 NRFAELVLEKP--LDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTAL 235
Query: 473 LFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYL----LGP 528
L I+V D NDN P F Q TVS+PEN+ PG +++++ATD D G N E+ Y + P
Sbjct: 236 LTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISP 295
Query: 529 DAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNS 588
A F L RTG L V +LD E+ Y + AKD G + ++ V V ++D NDN+
Sbjct: 296 RARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNA 355
Query: 589 PVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTG---V 645
P + + K V E V L +VTD D +N V +L + F + S
Sbjct: 356 PEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVP-FRLKSSFKNYYT 414
Query: 646 IRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYEL 705
I DRE +SYT V A D G + S+S + + V DVNDN P F P Y+
Sbjct: 415 IVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDV---Y 471
Query: 706 VLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIV-----GGNTRDLFAIDQETGNITLMEKC 760
V + PG ++ V A D D G NA++ YSI+ G + +I+ E G + +
Sbjct: 472 VTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSF 531
Query: 761 DVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 803
D L V+A D G P +L VN+ + + NA I
Sbjct: 532 DYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAI 574
>gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]
Length = 896
Score = 348 bits (892), Expect = 2e-95
Identities = 226/678 (33%), Positives = 352/678 (51%), Gaps = 57/678 (8%)
Query: 48 NYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFT 107
+YT++EE +GN+ +DL L + + + F+ V P + + +TG ++
Sbjct: 21 HYTVQEEQEHGTFVGNIAEDLGLDI----TKLSARGFQTV-PNSRTPYLDLNLETGVLYV 75
Query: 108 TGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINI 167
+IDRE++C P C +EV + + L ++ + DINDN P FP + +
Sbjct: 76 N-EKIDREQICKQSPS---CVLHLEVFL--ENPLELFQVEIEVLDINDNPPSFPEPDLTV 129
Query: 168 SIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKE 227
I E++ +++ L +A DPDVG N +++YE I + F LDV +G++ +L+++K
Sbjct: 130 EISESATPGTRFPLESAFDPDVGTNSLRDYE-ITPNSYFSLDVQTQGDGNRFAELVLEKP 188
Query: 228 LDREEKDTYVMKVKVEDGGF-------------------PQRSSTAILQVSVTDTNDNHP 268
LDRE++ + + DGG QR+ TA+L + V D+NDN P
Sbjct: 189 LDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVP 248
Query: 269 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 328
F + VS+PEN+P GT V QL+ATD D G+N ++ +SFS+ +S AR LF L+ TG
Sbjct: 249 AFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTG 308
Query: 329 LITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVN 386
+ + LD EE+P +++ V A D G +PA VLV V D NDN P I + V
Sbjct: 309 RLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAV- 367
Query: 387 DTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLD 446
SE T +AL +VTD+D++ NG+V C ++PFRL+ F N + + A LD
Sbjct: 368 -----SEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSFKNYYTIVTEAPLD 422
Query: 447 YESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQL 506
E+ Y + ++A D G+P L+ S + ++V D NDNAP F+Q V + ENN PG +
Sbjct: 423 REAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYI 482
Query: 507 MKVSATDADSGPNAEINY------LLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFT 560
VSATD D G NA++ Y + G S++ G L ++ D E+ + F
Sbjct: 483 YAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQ 542
Query: 561 ILAKDNGVP-PLTSNVTVFVSIIDQNDNSPVFT---HNEYKFYVPENLPRHGTVGL---- 612
+ A+D G P L N TV + I+DQNDN+P E LPR G
Sbjct: 543 VEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTR 602
Query: 613 ITVTDPDYGDNSAVTLSIL--DENDDFTIDSQTGVIRP--NISFDREKQESYTFYVKAED 668
+ D D G+N+ +T SI+ +E + F +D +TG +R + R+ Q Y ++ D
Sbjct: 603 VAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRD 662
Query: 669 GGRVSRSSSAKVTINVVD 686
G+ SS+A + + +VD
Sbjct: 663 HGQPPLSSTATLVVQLVD 680
Score = 233 bits (593), Expect = 9e-61
Identities = 178/588 (30%), Positives = 272/588 (46%), Gaps = 58/588 (9%)
Query: 256 LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSN 315
+++ V D NDN P F E ++ V I E+A GT A D D+G N+ + +
Sbjct: 108 VEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEIT----- 162
Query: 316 IARRLFHLNATT-------GLITIKEPLDREETPNHKLLVLASDGG-------------- 354
F L+ T + +++PLDRE+ H+ ++ A DGG
Sbjct: 163 -PNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGG 221
Query: 355 --LMPAR-----AMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVT 407
L P + A++ + V D NDNVP+ D PV TV L EN P T + + T
Sbjct: 222 AGLPPQQQRTGTALLTIRVLDSNDNVPAFD-----QPVY-TVSLPENSPPGTLVIQLNAT 275
Query: 408 DKDADHNGRVTCFTDHEIPFRLRPVFS---NQFLLENAAYLDYESTKEYAIKLLAADAGK 464
D D NG V I R R +F LE + LDYE + Y + + A D G
Sbjct: 276 DPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGP 335
Query: 465 PPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINY 524
+ + ++V D NDNAP + S V ++ E +PG + S TD DS N ++
Sbjct: 336 NAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQC 395
Query: 525 LLGPDAPPEFSLDRRTGMLTVVKK-LDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIID 583
L D P + V + LDRE D Y T++A+D G P L+++ ++ V + D
Sbjct: 396 ELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSD 455
Query: 584 QNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDD------- 636
NDN+P F+ Y YV EN + ++ TD D G N+ + SIL+
Sbjct: 456 VNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTY 515
Query: 637 FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSR-SSSAKVTINVVDVNDNKPVFI 695
+I+S+ G + SFD E+ + ++F V+A D G + +A V I +VD NDN P +
Sbjct: 516 VSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIV 575
Query: 696 VPPYNYS----YELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQET 751
P + E++ S PG ++ +V AVD D G NA + YSIV GN +LF +D T
Sbjct: 576 APLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRT 635
Query: 752 GNITLMEKCDV--TDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESV 797
G + + + ++++ D GQP + +V V+ +V
Sbjct: 636 GELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAV 683
Score = 190 bits (482), Expect = 7e-48
Identities = 178/583 (30%), Positives = 256/583 (43%), Gaps = 78/583 (13%)
Query: 273 TEIEVSIPENAPVGTSVTQLHATDADIG-ENAKIHFSFSNLVSNIARRLFHLNATTGLIT 331
+++ ++ E GT V + D+G + K+ V N LN TG++
Sbjct: 18 SQLHYTVQEEQEHGTFVGNIAE---DLGLDITKLSARGFQTVPNSRTPYLDLNLETGVLY 74
Query: 332 IKEPLDREE----TPN---HKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNP 384
+ E +DRE+ +P+ H + L + L V + V D+NDN PS P
Sbjct: 75 VNEKIDREQICKQSPSCVLHLEVFLENPLELF----QVEIEVLDINDNPPSF-------P 123
Query: 385 VND-TVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFS--------- 434
D TV +SE+ T+ L + D D N D+EI FS
Sbjct: 124 EPDLTVEISESATPGTRFPLESAFDPDVGTNS----LRDYEIT--PNSYFSLDVQTQGDG 177
Query: 435 NQF---LLENAAYLDYESTKEYAIKLLAAD----------------AGKPPLNQ---SAM 472
N+F +LE LD E + L A D AG PP Q +A+
Sbjct: 178 NRFAELVLEKP--LDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTAL 235
Query: 473 LFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYL----LGP 528
L I+V D NDN P F Q TVS+PEN+ PG +++++ATD D G N E+ Y + P
Sbjct: 236 LTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISP 295
Query: 529 DAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNS 588
A F L RTG L V +LD E+ Y + AKD G + ++ V V ++D NDN+
Sbjct: 296 RARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNA 355
Query: 589 PVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTG---V 645
P + + K V E V L +VTD D +N V +L + F + S
Sbjct: 356 PEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVP-FRLKSSFKNYYT 414
Query: 646 IRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYEL 705
I DRE +SYT V A D G + S+S + + V DVNDN P F P Y+
Sbjct: 415 IVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDV---Y 471
Query: 706 VLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIV-----GGNTRDLFAIDQETGNITLMEKC 760
V + PG ++ V A D D G NA++ YSI+ G + +I+ E G + +
Sbjct: 472 VTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSF 531
Query: 761 DVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI 803
D L V+A D G P +L VN+ + + NA I
Sbjct: 532 DYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAI 574
>gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 346 bits (888), Expect = 6e-95
Identities = 231/691 (33%), Positives = 352/691 (50%), Gaps = 62/691 (8%)
Query: 49 YTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTT 108
Y++ EE + +G++ KDL L P + ++ + G L + + +G + T
Sbjct: 33 YSVSEETDKGSFVGDIAKDLGLE--PRELAERGVR---IISRGRTQLFALNQRSGSLVTA 87
Query: 109 GARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINIS 168
G RIDRE++CA R C V IL ++ L I I DINDN P F IN+
Sbjct: 88 G-RIDREEICAQSAR---CL--VNFNILMEDKMNLYPIDVEIIDINDNVPRFLTEEINVK 141
Query: 169 IPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKEL 228
I EN+A ++ L A DPDVG N +Q+Y+L +++ F L V + K P+L++++ L
Sbjct: 142 IMENTAPGVRFPLSEAGDPDVGTNSLQSYQLSPNRH-FSLAVQSGDDETKYPELVLERVL 200
Query: 229 DREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTS 288
DREE+ + + + DGG P RSSTA +QV+V D ND+ PVF + +V++PEN PVGT
Sbjct: 201 DREEERVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLPQYQVTVPENVPVGTR 260
Query: 289 VTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLV 348
+ +HA D D G N ++ +SF + + + +FHLN+ TG I+ E LD EET +++ V
Sbjct: 261 LLTVHAIDLDEGVNGEVTYSFRKITPKLPK-MFHLNSLTGEISTLEGLDYEETAFYEMEV 319
Query: 349 LASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTD 408
A DG +A VL+ V DVNDN P + + + + + E+ PL T IAL + D
Sbjct: 320 QAQDGPGSLTKAKVLITVLDVNDNAPEVTMTSLSSSI------PEDTPLGTVIALFYLQD 373
Query: 409 KDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLN 468
+D+ NG VTC +PF+L N + L LD E+ Y I L A D G PPL+
Sbjct: 374 RDSGKNGEVTCTIPENLPFKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGTPPLS 433
Query: 469 QSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGP 528
+ +F++V D NDN P F S +V I ENN G + V+A D DS NA+I Y L
Sbjct: 434 RETHIFMQVADTNDNPPTFPHSSYSVYIAENNPRGASIFLVTAQDHDSEDNAQITYSLAE 493
Query: 529 D----APPE--FSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSII 582
D AP S++ TG+L ++ D E+ + + A D+G PPL+SN+++ + ++
Sbjct: 494 DTIQGAPVSSYVSINSDTGVLYALQSFDYEQLRELQLRVTAHDSGDPPLSSNMSLSLFVL 553
Query: 583 DQNDNSPVFTHNEYKFYVPENLPRHGTVGL---------------ITVTDPDYGDNSAVT 627
DQNDN P + LP G+ G+ + D D G N+ ++
Sbjct: 554 DQNDNPPEILY--------PALPTDGSTGMELAPRSAEPGYLVTKVVAVDKDSGQNAWLS 605
Query: 628 LSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVV 685
+L ++ F + TG +R + + V +D G+ S++ +T+ V
Sbjct: 606 YLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVA 665
Query: 686 DVNDNKPVFIVP---------PYNYSYELVL 707
D+ P + PYNY L L
Sbjct: 666 ---DSIPEVLADLGSLEPSDGPYNYDLTLYL 693
Score = 246 bits (628), Expect = 8e-65
Identities = 184/567 (32%), Positives = 267/567 (47%), Gaps = 42/567 (7%)
Query: 256 LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSN 315
+ V + D NDN P F EI V I EN G A D D+G N+ + S
Sbjct: 119 IDVEIIDINDNVPRFLTEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQLS----- 173
Query: 316 IARRLFHLNATTGLITIKEP-------LDREETPNHKLLVLASDGGLMP--ARAMVLVNV 366
R F L +G K P LDREE H L++ ASDGG P + A + V V
Sbjct: 174 -PNRHFSLAVQSGDDETKYPELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTV 232
Query: 367 TDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIP 426
DVND+ P + V + EN+P+ T++ + D D NG VT ++ +I
Sbjct: 233 VDVNDHTPVFSLPQY------QVTVPENVPVGTRLLTVHAIDLDEGVNGEVT-YSFRKIT 285
Query: 427 FRLRPVFSNQFL---LENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDN 483
+L +F L + LDYE T Y +++ A D P A + I V D NDN
Sbjct: 286 PKLPKMFHLNSLTGEISTLEGLDYEETAFYEMEVQAQDG--PGSLTKAKVLITVLDVNDN 343
Query: 484 APVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAP--PEFSLDRRTG 541
AP T + ++ SIPE+ G + D DSG N E+ + + P E S+D
Sbjct: 344 APEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYR 403
Query: 542 MLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVP 601
++T K LDRE Y T+ A D G PPL+ +F+ + D NDN P F H+ Y Y+
Sbjct: 404 LVTT-KNLDRETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIA 462
Query: 602 ENLPRHGTVGLITVTDPDYGDNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDR 654
EN PR ++ L+T D D DN+ +T S+ ++ + +I+S TGV+ SFD
Sbjct: 463 ENNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYALQSFDY 522
Query: 655 EKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPY----NYSYELVLPST 710
E+ V A D G SS+ +++ V+D NDN P + P + EL S
Sbjct: 523 EQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYPALPTDGSTGMELAPRSA 582
Query: 711 NPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRV 770
PG +V +V+AVD D+G NA + Y ++ + LFA+ TG + D +
Sbjct: 583 EPGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSL 642
Query: 771 LVKANDLGQPDSLFSVVIVNLFVNESV 797
+V D GQP L + V + + V +S+
Sbjct: 643 VVAVQDHGQP-PLSATVTLTVAVADSI 668
>gi|14196477 protocadherin gamma subfamily A, 7 isoform 2 precursor
[Homo sapiens]
Length = 817
Score = 346 bits (888), Expect = 6e-95
Identities = 231/691 (33%), Positives = 352/691 (50%), Gaps = 62/691 (8%)
Query: 49 YTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTT 108
Y++ EE + +G++ KDL L P + ++ + G L + + +G + T
Sbjct: 33 YSVSEETDKGSFVGDIAKDLGLE--PRELAERGVR---IISRGRTQLFALNQRSGSLVTA 87
Query: 109 GARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINIS 168
G RIDRE++CA R C V IL ++ L I I DINDN P F IN+
Sbjct: 88 G-RIDREEICAQSAR---CL--VNFNILMEDKMNLYPIDVEIIDINDNVPRFLTEEINVK 141
Query: 169 IPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKEL 228
I EN+A ++ L A DPDVG N +Q+Y+L +++ F L V + K P+L++++ L
Sbjct: 142 IMENTAPGVRFPLSEAGDPDVGTNSLQSYQLSPNRH-FSLAVQSGDDETKYPELVLERVL 200
Query: 229 DREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTS 288
DREE+ + + + DGG P RSSTA +QV+V D ND+ PVF + +V++PEN PVGT
Sbjct: 201 DREEERVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLPQYQVTVPENVPVGTR 260
Query: 289 VTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLV 348
+ +HA D D G N ++ +SF + + + +FHLN+ TG I+ E LD EET +++ V
Sbjct: 261 LLTVHAIDLDEGVNGEVTYSFRKITPKLPK-MFHLNSLTGEISTLEGLDYEETAFYEMEV 319
Query: 349 LASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTD 408
A DG +A VL+ V DVNDN P + + + + + E+ PL T IAL + D
Sbjct: 320 QAQDGPGSLTKAKVLITVLDVNDNAPEVTMTSLSSSI------PEDTPLGTVIALFYLQD 373
Query: 409 KDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLN 468
+D+ NG VTC +PF+L N + L LD E+ Y I L A D G PPL+
Sbjct: 374 RDSGKNGEVTCTIPENLPFKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGTPPLS 433
Query: 469 QSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGP 528
+ +F++V D NDN P F S +V I ENN G + V+A D DS NA+I Y L
Sbjct: 434 RETHIFMQVADTNDNPPTFPHSSYSVYIAENNPRGASIFLVTAQDHDSEDNAQITYSLAE 493
Query: 529 D----APPE--FSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSII 582
D AP S++ TG+L ++ D E+ + + A D+G PPL+SN+++ + ++
Sbjct: 494 DTIQGAPVSSYVSINSDTGVLYALQSFDYEQLRELQLRVTAHDSGDPPLSSNMSLSLFVL 553
Query: 583 DQNDNSPVFTHNEYKFYVPENLPRHGTVGL---------------ITVTDPDYGDNSAVT 627
DQNDN P + LP G+ G+ + D D G N+ ++
Sbjct: 554 DQNDNPPEILY--------PALPTDGSTGMELAPRSAEPGYLVTKVVAVDKDSGQNAWLS 605
Query: 628 LSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVV 685
+L ++ F + TG +R + + V +D G+ S++ +T+ V
Sbjct: 606 YLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVA 665
Query: 686 DVNDNKPVFIVP---------PYNYSYELVL 707
D+ P + PYNY L L
Sbjct: 666 ---DSIPEVLADLGSLEPSDGPYNYDLTLYL 693
Score = 246 bits (628), Expect = 8e-65
Identities = 184/567 (32%), Positives = 267/567 (47%), Gaps = 42/567 (7%)
Query: 256 LQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSN 315
+ V + D NDN P F EI V I EN G A D D+G N+ + S
Sbjct: 119 IDVEIIDINDNVPRFLTEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQLS----- 173
Query: 316 IARRLFHLNATTGLITIKEP-------LDREETPNHKLLVLASDGGLMP--ARAMVLVNV 366
R F L +G K P LDREE H L++ ASDGG P + A + V V
Sbjct: 174 -PNRHFSLAVQSGDDETKYPELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTV 232
Query: 367 TDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIP 426
DVND+ P + V + EN+P+ T++ + D D NG VT ++ +I
Sbjct: 233 VDVNDHTPVFSLPQY------QVTVPENVPVGTRLLTVHAIDLDEGVNGEVT-YSFRKIT 285
Query: 427 FRLRPVFSNQFL---LENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDN 483
+L +F L + LDYE T Y +++ A D P A + I V D NDN
Sbjct: 286 PKLPKMFHLNSLTGEISTLEGLDYEETAFYEMEVQAQDG--PGSLTKAKVLITVLDVNDN 343
Query: 484 APVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAP--PEFSLDRRTG 541
AP T + ++ SIPE+ G + D DSG N E+ + + P E S+D
Sbjct: 344 APEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYR 403
Query: 542 MLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVP 601
++T K LDRE Y T+ A D G PPL+ +F+ + D NDN P F H+ Y Y+
Sbjct: 404 LVTT-KNLDRETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIA 462
Query: 602 ENLPRHGTVGLITVTDPDYGDNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDR 654
EN PR ++ L+T D D DN+ +T S+ ++ + +I+S TGV+ SFD
Sbjct: 463 ENNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYALQSFDY 522
Query: 655 EKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPY----NYSYELVLPST 710
E+ V A D G SS+ +++ V+D NDN P + P + EL S
Sbjct: 523 EQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYPALPTDGSTGMELAPRSA 582
Query: 711 NPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRV 770
PG +V +V+AVD D+G NA + Y ++ + LFA+ TG + D +
Sbjct: 583 EPGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSL 642
Query: 771 LVKANDLGQPDSLFSVVIVNLFVNESV 797
+V D GQP L + V + + V +S+
Sbjct: 643 VVAVQDHGQP-PLSATVTLTVAVADSI 668
>gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precursor
[Homo sapiens]
Length = 837
Score = 345 bits (885), Expect = 1e-94
Identities = 214/681 (31%), Positives = 351/681 (51%), Gaps = 54/681 (7%)
Query: 33 VLLVCVVFHS----GAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVY 88
+LL+C+ + A++ Y++ EE + +GN+ KDL L P + ++ +
Sbjct: 14 LLLLCIFLGTLRGFRARQIRYSVPEETEKGSFVGNISKDLGLE--PRELAKRGVR---IV 68
Query: 89 KTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRF 148
G L + +G + T G RIDRE+LC + CF +E +L ++ ++ +
Sbjct: 69 SRGKTQLFAVNPRSGSLITAG-RIDREELCETV---SSCFLNME--LLVEDTLKIYGVEV 122
Query: 149 LIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGL 208
I DINDNAP F + I + E++ +++ LP A DPDVG+N +Q+Y+L N F L
Sbjct: 123 EIIDINDNAPSFQEDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQL-SPNNYFSL 181
Query: 209 DVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHP 268
+ +G K P+L+++ LDRE++ +++ + DGG P R ++V V D ND+ P
Sbjct: 182 QLRGRTDGAKNPELVLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIP 241
Query: 269 VFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG 328
+F ++ VS+PEN GT V ++ATD D G N ++ +SF N+ S A +F L++ TG
Sbjct: 242 MFTQSVYRVSVPENISSGTRVLMVNATDPDEGINGEVMYSFRNMESK-ASEIFQLDSQTG 300
Query: 329 LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT 388
+ ++ LD E+ +++ + DGG + +L+ V DVNDN P I I +N +
Sbjct: 301 EVQVRGSLDFEKYRFYEMEIQGQDGGGLFTTTTMLITVVDVNDNAPEITITSSINSI--- 357
Query: 389 VVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYE 448
EN P T IAL+ V D+D+ NG+V+CF + +PF+L + N + L + LD E
Sbjct: 358 ---LENSPPGTVIALLNVQDQDSGENGQVSCFIPNHLPFKLEKTYGNYYKLITSRVLDRE 414
Query: 449 STKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMK 508
+ Y I L A D G PPL+ +++ V D+NDN PVF S + IPENN G +
Sbjct: 415 LVQSYNITLTATDQGSPPLSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFS 474
Query: 509 VSATDADSGPNAEINYLLGPDA------PPEFSLDRRTGMLTVVKKLDREKEDKYLFTIL 562
V+A D DS NA + Y L D S++ TG+L ++ D E+ ++
Sbjct: 475 VTALDPDSKQNALVTYSLTDDTVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVI 534
Query: 563 AKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGL---------- 612
A+D+G PPL+SNV++ + ++DQNDN+P + LP G+ G+
Sbjct: 535 ARDSGDPPLSSNVSLSLFVLDQNDNAPEILY--------PALPTDGSTGVELAPRSAEPG 586
Query: 613 -----ITVTDPDYGDNSAVTLSILDENDD--FTIDSQTGVIRPNISFDREKQESYTFYVK 665
+ D D G N+ ++ +L ++ F + TG +R + + V
Sbjct: 587 YLVTKVVAVDKDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVA 646
Query: 666 AEDGGRVSRSSSAKVTINVVD 686
+D G+ S++ +T+ V D
Sbjct: 647 VQDHGQPPLSATVTLTVAVAD 667
Score = 251 bits (642), Expect = 2e-66
Identities = 211/725 (29%), Positives = 334/725 (46%), Gaps = 71/725 (9%)
Query: 160 FPATVINISIPENSAINSKYTLPAAVDPDVGIN-------GVQNYELIKSQNIFGLDVIE 212
F A I S+PE + K + + D+G+ GV+ K+Q +F ++
Sbjct: 27 FRARQIRYSVPEET---EKGSFVGNISKDLGLEPRELAKRGVRIVSRGKTQ-LFAVN--- 79
Query: 213 TPEGDKMPQLIVQKELDREEKDTYV------MKVKVEDGGFPQRSSTAILQVSVTDTNDN 266
+ LI +DREE V M++ VED ++V + D NDN
Sbjct: 80 ----PRSGSLITAGRIDREELCETVSSCFLNMELLVED-----TLKIYGVEVEIIDINDN 130
Query: 267 HPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFS-NLVSNIARRLFHLNA 325
P F+E E+E+ + E+A G +A D D+G N+ + S N ++ R A
Sbjct: 131 APSFQEDEVEIKVSEHAIPGARFALPNARDPDVGVNSLQSYQLSPNNYFSLQLRGRTDGA 190
Query: 326 TTGLITIKEPLDREETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVN 383
+ ++ LDRE+ H LL+ A DGG + + V V DVND++P
Sbjct: 191 KNPELVLEGSLDREKEAAHLLLLTALDGGDPIRKGAVPIRVVVLDVNDHIPMFTQSVY-- 248
Query: 384 PVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVF---SNQFLLE 440
V + ENI T++ ++ TD D NG V ++ + + +F S ++
Sbjct: 249 ----RVSVPENISSGTRVLMVNATDPDEGINGEVM-YSFRNMESKASEIFQLDSQTGEVQ 303
Query: 441 NAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENN 500
LD+E + Y +++ D G L + + I V D NDNAP T + SI EN+
Sbjct: 304 VRGSLDFEKYRFYEMEIQGQDGGG--LFTTTTMLITVVDVNDNAPEITITSSINSILENS 361
Query: 501 SPGIQLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTG---MLTVVKKLDREKEDKY 557
PG + ++ D DSG N +++ + P F L++ G L + LDRE Y
Sbjct: 362 PPGTVIALLNVQDQDSGENGQVSCFIPNHLP--FKLEKTYGNYYKLITSRVLDRELVQSY 419
Query: 558 LFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTD 617
T+ A D G PPL++ V++++ D NDN PVF H+ Y Y+PEN PR ++ +T D
Sbjct: 420 NITLTATDQGSPPLSAETHVWLNVADDNDNPPVFPHSSYSAYIPENNPRGASIFSVTALD 479
Query: 618 PDYGDNSAVTLSILDE-------NDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG 670
PD N+ VT S+ D+ + +I+S TGV+ SFD E+ V A D G
Sbjct: 480 PDSKQNALVTYSLTDDTVQGVPLSSYVSINSNTGVLYALQSFDYEQFRDLELRVIARDSG 539
Query: 671 RVSRSSSAKVTINVVDVNDNKPVFIVPPY----NYSYELVLPSTNPGTVVFQVIAVDNDT 726
SS+ +++ V+D NDN P + P + EL S PG +V +V+AVD D+
Sbjct: 540 DPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDS 599
Query: 727 GMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSV 786
G NA + Y ++ + LFA+ + TG + D ++V D GQP +V
Sbjct: 600 GQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATV 659
Query: 787 VIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVV 846
+ +V A I E++ N+E +D+S Y+ + VAAV+ V
Sbjct: 660 TL-------TVAVADSIPEVLADLGSLESLANSETSDLSL----YLVVAVAAVSCIFLVF 708
Query: 847 VVIFI 851
V++ +
Sbjct: 709 VIVLL 713
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,738,830
Number of Sequences: 37866
Number of extensions: 1790393
Number of successful extensions: 14090
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 190
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 4655
Number of HSP's gapped (non-prelim): 949
length of query: 1037
length of database: 18,247,518
effective HSP length: 112
effective length of query: 925
effective length of database: 14,006,526
effective search space: 12956036550
effective search space used: 12956036550
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.