Guide to the Human Genome
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Name: F12 Sequence: fasta or formatted (615aa) NCBI GI: 145275213
Description:

coagulation factor XII precursor

Referenced in:

Coagulation
Fibronectin Family

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.6         53           2
 C cysteine            6.5         40           1
 D aspartate           3.6         22           1
 E glutamate           5.2         32           2
 F phenylalanine       2.6         16           2
 G glycine             8.0         49           2
 H histidine           4.4         27           1
 I isoleucine          1.5          9           2
 K lysine              3.1         19           2
 L leucine             9.9         61           4
 M methionine          0.8          5           1
 N asparagine          2.1         13           1
 P proline             9.1         56           2
 Q glutamine           6.0         37           1
 R arginine            6.5         40           2
 S serine              6.2         38           2
 T threonine           5.7         35           2
 V valine              5.0         31           2
 W tryptophan          2.1         13           1
 Y tyrosine            3.1         19           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   coagulation factor XII precursor 
HGFAC                 0.332   HGF activator preproprotein 
PLAT                  0.190   plasminogen activator, tissue isoform 1 preproprotein...
PLAU                  0.175   plasminogen activator, urokinase isoform 2 
PLAU                  0.175   plasminogen activator, urokinase isoform 1 preproprot...
HABP2                 0.171   hyaluronan binding protein 2 preproprotein 
PLG                   0.145   plasminogen 
LPA                   0.133   lipoprotein Lp(a) precursor 
PLAT                  0.123   plasminogen activator, tissue isoform 3 preproprotei...
TMPRSS3               0.116   transmembrane protease, serine 3 isoform 1 
PRSS33                0.106   protease, serine, 33 
HPN                   0.106   hepsin 
HPN                   0.106   hepsin 
PRSS36                0.105   protease, serine, 36 
TMPRSS11D             0.105   transmembrane protease, serine 11D 
TMPRSS11A             0.105   transmembrane protease, serine 11A isoform 2 
TMPRSS11A             0.105   transmembrane protease, serine 11A isoform 1 
TMPRSS5               0.104   transmembrane protease, serine 5 
TMPRSS11B             0.103   transmembrane protease, serine 11B 
ACR                   0.100   acrosin precursor 
TMPRSS9               0.100   transmembrane protease, serine 9 
PRSS8                 0.099   prostasin preproprotein 
F11                   0.099   coagulation factor XI precursor 
TMPRSS13              0.099   transmembrane protease, serine 13 
OVCH2                 0.099   ovochymase 2 
TMPRSS12              0.097   transmembrane protease, serine 12 
PRSS1                 0.097   protease, serine, 1 preproprotein 
ST14                  0.096   matriptase 
KLKB1                 0.095   plasma kallikrein B1 precursor 
TMPRSS6               0.095   transmembrane protease, serine 6 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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