BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapiens] (798 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi... 1566 0.0 gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] 1561 0.0 gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi... 1276 0.0 gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] 1276 0.0 gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi... 1275 0.0 gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] 1272 0.0 gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens] 1261 0.0 gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapi... 1259 0.0 gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapi... 1237 0.0 gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] 1236 0.0 gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap... 1230 0.0 gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapi... 1229 0.0 gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi... 1228 0.0 gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] 1228 0.0 gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapi... 1212 0.0 gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapi... 1210 0.0 gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] 1210 0.0 gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] 1209 0.0 gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi... 1206 0.0 gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] 1206 0.0 gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sap... 1201 0.0 gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapi... 1201 0.0 gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sap... 1184 0.0 gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapi... 1184 0.0 gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sap... 1180 0.0 gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapi... 1180 0.0 gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapi... 793 0.0 gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapi... 786 0.0 gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sap... 785 0.0 gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precurs... 607 e-173 >gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapiens] Length = 798 Score = 1566 bits (4054), Expect = 0.0 Identities = 798/798 (100%), Positives = 798/798 (100%) Query: 1 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD Sbjct: 61 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL Sbjct: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180 Query: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP Sbjct: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240 Query: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG Sbjct: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300 Query: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR Sbjct: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360 Query: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA Sbjct: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSR 780 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSR Sbjct: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSR 780 Query: 781 DREDQLQTTEESFAKVSV 798 DREDQLQTTEESFAKVSV Sbjct: 781 DREDQLQTTEESFAKVSV 798 >gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] Length = 947 Score = 1561 bits (4042), Expect = 0.0 Identities = 795/795 (100%), Positives = 795/795 (100%) Query: 1 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD Sbjct: 61 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL Sbjct: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180 Query: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP Sbjct: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240 Query: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG Sbjct: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300 Query: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR Sbjct: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360 Query: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA Sbjct: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSR 780 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSR Sbjct: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSR 780 Query: 781 DREDQLQTTEESFAK 795 DREDQLQTTEESFAK Sbjct: 781 DREDQLQTTEESFAK 795 >gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapiens] Length = 789 Score = 1276 bits (3303), Expect = 0.0 Identities = 654/775 (84%), Positives = 695/775 (89%) Query: 12 RRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGR 71 R LLL +++LAAWEAG GQLHYSV EEAKHG FVGRIAQDLGLELAELVPRLFR K R Sbjct: 12 RHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFR 71 Query: 72 GGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP 131 G LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIV+RPLQVFHVDVEV+DINDNPP Sbjct: 72 GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPP 131 Query: 132 VFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKG 191 VFPATQ+NL IAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYF L+ P ++ VK Sbjct: 132 VFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191 Query: 192 LGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRL 251 LGL+LRK LDREE PE+ L+LTATDGGKPELTGTVQLLITVLD NDNAP FDRT+Y V+L Sbjct: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251 Query: 252 LENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFE 311 ENV GTLVI NASDLDEGLNGDI+YSFS+D+SP++KSKFH+DP++G I V G++DFE Sbjct: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311 Query: 312 ESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIAL 371 ES++++I VE +DKG PL+GHC V+VEV D NDN P L SLSLPI EDA GTVI L Sbjct: 312 ESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITL 371 Query: 372 ISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431 ISV D+D GVNG VTCSLT VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG Sbjct: 372 ISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431 Query: 432 SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVS 491 SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NALVS Sbjct: 432 SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVS 491 Query: 492 YSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTL 551 YSLVE RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLGSNVTL Sbjct: 492 YSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551 Query: 552 QVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYEL 611 QVFVLDENDNAPALLAPR GGTGGAV ELVP SVG GHVVAKVRAVDADSGYNAWLSYEL Sbjct: 552 QVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYEL 611 Query: 612 QPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVE 671 QP GA IPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEP+LTATATVLVSLVE Sbjct: 612 QPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVE 671 Query: 672 SGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGA 731 SGQAPKASSRA +G GP+ LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA +EGA Sbjct: 672 SGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEGA 731 Query: 732 CAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQL 786 C+ KPTLVCSSAVGSWS+SQQRR RVCSGEGPPKTDLMAFSPSLP D + Sbjct: 732 CSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNV 786 >gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] Length = 937 Score = 1276 bits (3302), Expect = 0.0 Identities = 654/773 (84%), Positives = 694/773 (89%) Query: 12 RRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGR 71 R LLL +++LAAWEAG GQLHYSV EEAKHG FVGRIAQDLGLELAELVPRLFR K R Sbjct: 12 RHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFR 71 Query: 72 GGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP 131 G LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIV+RPLQVFHVDVEV+DINDNPP Sbjct: 72 GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPP 131 Query: 132 VFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKG 191 VFPATQ+NL IAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYF L+ P ++ VK Sbjct: 132 VFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191 Query: 192 LGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRL 251 LGL+LRK LDREE PE+ L+LTATDGGKPELTGTVQLLITVLD NDNAP FDRT+Y V+L Sbjct: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251 Query: 252 LENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFE 311 ENV GTLVI NASDLDEGLNGDI+YSFS+D+SP++KSKFH+DP++G I V G++DFE Sbjct: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311 Query: 312 ESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIAL 371 ES++++I VE +DKG PL+GHC V+VEV D NDN P L SLSLPI EDA GTVI L Sbjct: 312 ESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITL 371 Query: 372 ISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431 ISV D+D GVNG VTCSLT VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG Sbjct: 372 ISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431 Query: 432 SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVS 491 SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NALVS Sbjct: 432 SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVS 491 Query: 492 YSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTL 551 YSLVE RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLGSNVTL Sbjct: 492 YSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551 Query: 552 QVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYEL 611 QVFVLDENDNAPALLAPR GGTGGAV ELVP SVG GHVVAKVRAVDADSGYNAWLSYEL Sbjct: 552 QVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYEL 611 Query: 612 QPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVE 671 QP GA IPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEP+LTATATVLVSLVE Sbjct: 612 QPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVE 671 Query: 672 SGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGA 731 SGQAPKASSRA +G GP+ LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA +EGA Sbjct: 672 SGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEGA 731 Query: 732 CAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDRED 784 C+ KPTLVCSSAVGSWS+SQQRR RVCSGEGPPKTDLMAFSPSLP D Sbjct: 732 CSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD 784 >gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapiens] Length = 824 Score = 1275 bits (3299), Expect = 0.0 Identities = 657/800 (82%), Positives = 707/800 (88%), Gaps = 3/800 (0%) Query: 1 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 M FSW ++ LLL LLLLAA E G+GQLHYSVSEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASK G LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180 VEV+DINDN PVFP KNL I+ESR SRF LEGASDADIG N+LLTY L EYF+L Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 Query: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240 + +DE +K LGL+L+K+L+RE+ P+ +L++TA DGGKPELTGT QL ITVLD NDNAP Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 Query: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300 AF+RTIYKVRLLEN PNGTLV+ +NA+DLDEG+N DI YSF+ D+S ++ SKFH+DP+ G Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 Query: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360 QI VKG IDFEESKSYEI VE DKG P+S HC V++E+ D NDNVP+L +SLSLP+ Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 Query: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 ED+PL TVIALISVSD+D GVNG VTCSLT HVPFKLVSTFKNYYSLVLDS LDRESVSA Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR GG GGAVSELVP SVG GHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDE DAPRHRLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 Query: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASS+A GA GP+AALVDVNVYLI+AICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPD-- 778 LRCSA PTEG C PGKPTLVCSSAVGSWSYSQQR+ RVCSGEG PKTDLMAFSPSLP Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 Query: 779 -SRDREDQLQTTEESFAKVS 797 SRDRE++ + AKVS Sbjct: 781 ISRDREEKQDVDVDLSAKVS 800 >gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1272 bits (3291), Expect = 0.0 Identities = 655/798 (82%), Positives = 705/798 (88%), Gaps = 3/798 (0%) Query: 1 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 M FSW ++ LLL LLLLAA E G+GQLHYSVSEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASK G LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180 VEV+DINDN PVFP KNL I+ESR SRF LEGASDADIG N+LLTY L EYF+L Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 Query: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240 + +DE +K LGL+L+K+L+RE+ P+ +L++TA DGGKPELTGT QL ITVLD NDNAP Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 Query: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300 AF+RTIYKVRLLEN PNGTLV+ +NA+DLDEG+N DI YSF+ D+S ++ SKFH+DP+ G Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 Query: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360 QI VKG IDFEESKSYEI VE DKG P+S HC V++E+ D NDNVP+L +SLSLP+ Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 Query: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 ED+PL TVIALISVSD+D GVNG VTCSLT HVPFKLVSTFKNYYSLVLDS LDRESVSA Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR GG GGAVSELVP SVG GHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDE DAPRHRLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 Query: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASS+A GA GP+AALVDVNVYLI+AICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPD-- 778 LRCSA PTEG C PGKPTLVCSSAVGSWSYSQQR+ RVCSGEG PKTDLMAFSPSLP Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 Query: 779 -SRDREDQLQTTEESFAK 795 SRDRE++ + AK Sbjct: 781 ISRDREEKQDVDVDLSAK 798 >gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens] Length = 842 Score = 1261 bits (3262), Expect = 0.0 Identities = 651/799 (81%), Positives = 701/799 (87%), Gaps = 3/799 (0%) Query: 1 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 M +S E + LLL LL+LA W G+GQLHYSV EEA+HGTFVGRIAQDLGLELAELV Sbjct: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120 PRLF++ SKGRG LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVD Sbjct: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180 VEV+DINDNPPVFPATQKNL IAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYF L Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 Query: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240 + P ++ VK LGL+LRK LDREE PE+ L+LTATDGGKPELTGTVQLLITVLD NDNAP Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 Query: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300 FDRT+Y V+L ENV GTLVI NASDLDEGLNGDI+YSFS+D+SP++KSKFH+DP++G Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 Query: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360 I V G++DFEES++++I VE +DKG PL+GHC ++VEV D NDN P L K+LS+P++ Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 Query: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 EDA LGTVIALISV D D NG VTCSLT HVPFKLVST+KNYYSLVLD ALDRESVSA Sbjct: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540 DADAQENALVSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDA Sbjct: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR GT GAVSE+V SVG G VV KVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQP T A IPFRVGLYTGEISTTRALDETDAPR RLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPK+SSRA VGA GP+ LVDVNVYLIIAICAVSSLLVLTLLLYT Sbjct: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 Query: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSL---P 777 LRCSA+PTEG CAPGKPTLVCSSAVGSWSYSQQRR RVCSGEG KTDLMAFSP L Sbjct: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 Query: 778 DSRDREDQLQTTEESFAKV 796 S +R + + +S KV Sbjct: 781 GSTERTGEPSASSDSTGKV 799 >gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1259 bits (3258), Expect = 0.0 Identities = 650/798 (81%), Positives = 700/798 (87%), Gaps = 3/798 (0%) Query: 1 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 M +S E + LLL LL+LA W G+GQLHYSV EEA+HGTFVGRIAQDLGLELAELV Sbjct: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120 PRLF++ SKGRG LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVD Sbjct: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180 VEV+DINDNPPVFPATQKNL IAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYF L Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 Query: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240 + P ++ VK LGL+LRK LDREE PE+ L+LTATDGGKPELTGTVQLLITVLD NDNAP Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 Query: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300 FDRT+Y V+L ENV GTLVI NASDLDEGLNGDI+YSFS+D+SP++KSKFH+DP++G Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 Query: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360 I V G++DFEES++++I VE +DKG PL+GHC ++VEV D NDN P L K+LS+P++ Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 Query: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 EDA LGTVIALISV D D NG VTCSLT HVPFKLVST+KNYYSLVLD ALDRESVSA Sbjct: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540 DADAQENALVSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDA Sbjct: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR GT GAVSE+V SVG G VV KVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQP T A IPFRVGLYTGEISTTRALDETDAPR RLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPK+SSRA VGA GP+ LVDVNVYLIIAICAVSSLLVLTLLLYT Sbjct: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 Query: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSL---P 777 LRCSA+PTEG CAPGKPTLVCSSAVGSWSYSQQRR RVCSGEG KTDLMAFSP L Sbjct: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 Query: 778 DSRDREDQLQTTEESFAK 795 S +R + + +S K Sbjct: 781 GSTERTGEPSASSDSTGK 798 >gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapiens] Length = 824 Score = 1237 bits (3201), Expect = 0.0 Identities = 633/785 (80%), Positives = 688/785 (87%), Gaps = 1/785 (0%) Query: 15 LLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGGL 74 LL LLLLAAWE G+GQL YSV EEAKHGTFVGRIAQDLGLEL ELVPRLFRVASK G L Sbjct: 15 LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74 Query: 75 LEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVFP 134 LEVNLQNGILFVNSRIDREELC RSAECSIH+EVIVDRPLQVFHV+VEV+DINDNPP+FP Sbjct: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134 Query: 135 ATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLGL 194 T K + ESR LDSRFPLEGASDADIG NALL+Y+LS +E+F L+ +DEL + L L Sbjct: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194 Query: 195 ILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLEN 254 +L KSLDREE E+ L+L ATDGGKPELTGTVQ+LI VLD NDN P F +++YKV+LLEN Sbjct: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254 Query: 255 VPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEESK 314 NGTLV+KLNASD DEG N +IVYS +D+S +++KF IDPI+G+I KG +D+EE+K Sbjct: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314 Query: 315 SYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALISV 374 SYEI V DKG +SGHC++ +++ D NDN P++ SLSLPI E+A LGTVIALI+V Sbjct: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374 Query: 375 SDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 SD+D G NG VTCSLT HVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS Sbjct: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 Query: 435 LWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494 LWAT SVS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL Sbjct: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494 Query: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQVF 554 VERRVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQV+ARDAGVPPLGSNVTLQVF Sbjct: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554 Query: 555 VLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQPG 614 VLDENDNAPALLAPRAG GAVSELVPWSVG GHVVAKVRAVDADSGYNAWLSYELQ G Sbjct: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614 Query: 615 TGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 TG ARIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEPALTATATVLVSLVESGQ Sbjct: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 Query: 675 APKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACAP 734 APKASSRA VGA G +A LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS PTEGA AP Sbjct: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734 Query: 735 GKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQLQTTEESF- 793 GKPTLVCSSAVGSWSYSQQRR RVCSGE PPKTDLMAFSPSL D ++ Q +E + Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEEKQLSESEYV 794 Query: 794 AKVSV 798 KVS+ Sbjct: 795 GKVSL 799 >gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] Length = 948 Score = 1236 bits (3199), Expect = 0.0 Identities = 630/779 (80%), Positives = 684/779 (87%) Query: 15 LLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGGL 74 LL LLLLAAWE G+GQL YSV EEAKHGTFVGRIAQDLGLEL ELVPRLFRVASK G L Sbjct: 15 LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74 Query: 75 LEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVFP 134 LEVNLQNGILFVNSRIDREELC RSAECSIH+EVIVDRPLQVFHV+VEV+DINDNPP+FP Sbjct: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134 Query: 135 ATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLGL 194 T K + ESR LDSRFPLEGASDADIG NALL+Y+LS +E+F L+ +DEL + L L Sbjct: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194 Query: 195 ILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLEN 254 +L KSLDREE E+ L+L ATDGGKPELTGTVQ+LI VLD NDN P F +++YKV+LLEN Sbjct: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254 Query: 255 VPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEESK 314 NGTLV+KLNASD DEG N +IVYS +D+S +++KF IDPI+G+I KG +D+EE+K Sbjct: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314 Query: 315 SYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALISV 374 SYEI V DKG +SGHC++ +++ D NDN P++ SLSLPI E+A LGTVIALI+V Sbjct: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374 Query: 375 SDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 SD+D G NG VTCSLT HVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS Sbjct: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 Query: 435 LWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494 LWAT SVS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL Sbjct: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494 Query: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQVF 554 VERRVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQV+ARDAGVPPLGSNVTLQVF Sbjct: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554 Query: 555 VLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQPG 614 VLDENDNAPALLAPRAG GAVSELVPWSVG GHVVAKVRAVDADSGYNAWLSYELQ G Sbjct: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614 Query: 615 TGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 TG ARIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEPALTATATVLVSLVESGQ Sbjct: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 Query: 675 APKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACAP 734 APKASSRA VGA G +A LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS PTEGA AP Sbjct: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734 Query: 735 GKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQLQTTEESF 793 GKPTLVCSSAVGSWSYSQQRR RVCSGE PPKTDLMAFSPSL D ++ Q +E + Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEEKQLSESEY 793 >gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sapiens] Length = 807 Score = 1230 bits (3182), Expect = 0.0 Identities = 633/798 (79%), Positives = 687/798 (86%), Gaps = 3/798 (0%) Query: 4 SWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRL 63 SW G R+LLL LL+LAAWE G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRL Sbjct: 4 SWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRL 63 Query: 64 FRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEV 123 FRVASK G LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHV+V+V Sbjct: 64 FRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKV 123 Query: 124 RDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKP 183 RDINDNPP+FP ++K + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF+L+ Sbjct: 124 RDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQ 183 Query: 184 PDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFD 243 E + L L+LRK+LDREE E L+LTA+DGGKPELTGTVQLLIT+LD NDNAP F Sbjct: 184 NSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFY 243 Query: 244 RTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQII 303 +++YKV +LEN NGTLVIKLNA+D D+G NGDIVYSF + P V F I+P G+I Sbjct: 244 QSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIR 303 Query: 304 VKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDA 363 KG +DFEE K YEI VE +DKG +P++GHC ++VEV D NDN P++ SLSLPIRED Sbjct: 304 TKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDT 363 Query: 364 PLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYEL 423 +IALISVSD+D G NG VTC+LT HVPFKLVST+KNYYSLVLDSALDRESVSAYEL Sbjct: 364 QPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYEL 423 Query: 424 VVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDAD 483 VVTARDGGSPSLWATASVSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DAD Sbjct: 424 VVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDAD 483 Query: 484 AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVP 543 AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARD+GVP Sbjct: 484 AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVP 543 Query: 544 PLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGY 603 PLGSNVTLQVFVLDENDNAPALL P AG GG VSEL+P SVG GHVVAKVRAVDADSGY Sbjct: 544 PLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGY 603 Query: 604 NAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATA 663 NAWLSYELQ GARIPFRVGLYTGEISTTR LDE DAP HRLLVLVKDHGEPALTATA Sbjct: 604 NAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATA 663 Query: 664 TVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 723 TVL+SLVESGQAP+ASSRA GAVGP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRC Sbjct: 664 TVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 723 Query: 724 SALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLP---DSR 780 SA PTEGACAPGKPTLVCSSA GSWSYSQQRRPRVCSGEGP KTDLMAFSPSLP S Sbjct: 724 SAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSA 783 Query: 781 DREDQLQTTEESFAKVSV 798 + Q + E +VS+ Sbjct: 784 EGTGQREEDSECLKEVSL 801 >gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1229 bits (3180), Expect = 0.0 Identities = 628/774 (81%), Positives = 678/774 (87%) Query: 4 SWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRL 63 SW G R+LLL LL+LAAWE G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRL Sbjct: 4 SWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRL 63 Query: 64 FRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEV 123 FRVASK G LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHV+V+V Sbjct: 64 FRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKV 123 Query: 124 RDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKP 183 RDINDNPP+FP ++K + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF+L+ Sbjct: 124 RDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQ 183 Query: 184 PDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFD 243 E + L L+LRK+LDREE E L+LTA+DGGKPELTGTVQLLIT+LD NDNAP F Sbjct: 184 NSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFY 243 Query: 244 RTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQII 303 +++YKV +LEN NGTLVIKLNA+D D+G NGDIVYSF + P V F I+P G+I Sbjct: 244 QSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIR 303 Query: 304 VKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDA 363 KG +DFEE K YEI VE +DKG +P++GHC ++VEV D NDN P++ SLSLPIRED Sbjct: 304 TKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDT 363 Query: 364 PLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYEL 423 +IALISVSD+D G NG VTC+LT HVPFKLVST+KNYYSLVLDSALDRESVSAYEL Sbjct: 364 QPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYEL 423 Query: 424 VVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDAD 483 VVTARDGGSPSLWATASVSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DAD Sbjct: 424 VVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDAD 483 Query: 484 AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVP 543 AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARD+GVP Sbjct: 484 AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVP 543 Query: 544 PLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGY 603 PLGSNVTLQVFVLDENDNAPALL P AG GG VSEL+P SVG GHVVAKVRAVDADSGY Sbjct: 544 PLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGY 603 Query: 604 NAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATA 663 NAWLSYELQ GARIPFRVGLYTGEISTTR LDE DAP HRLLVLVKDHGEPALTATA Sbjct: 604 NAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATA 663 Query: 664 TVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 723 TVL+SLVESGQAP+ASSRA GAVGP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRC Sbjct: 664 TVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 723 Query: 724 SALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLP 777 SA PTEGACAPGKPTLVCSSA GSWSYSQQRRPRVCSGEGP KTDLMAFSPSLP Sbjct: 724 SAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLP 777 >gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapiens] Length = 816 Score = 1228 bits (3178), Expect = 0.0 Identities = 631/779 (81%), Positives = 678/779 (87%) Query: 8 GQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 G RLLLL LLLA W+AG+GQLHYS+ EEAKHGTFVGRIAQDLGLELAELVPRLFRVA Sbjct: 7 GSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 66 Query: 68 SKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127 SKGRG LLEVNLQNGILFVNSRIDREELCRR AECSIHLEVIVDRPLQVFHV+V V+DIN Sbjct: 67 SKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDIN 126 Query: 128 DNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDE 187 DNPP F ++ L I ESR DSRFPLEGASD DIG NA L YRL+PNEYF L+ ++E Sbjct: 127 DNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEE 186 Query: 188 LVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIY 247 L L+LRKSLDREE E L++ ATDGGKPELTGTVQLLI VLDANDNAP FD++IY Sbjct: 187 ETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIY 246 Query: 248 KVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGY 307 VRLLEN P+GTLVIKLNASD DEG+N +IVY FSN + +VKSKF I+ TG+I V G Sbjct: 247 NVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGE 306 Query: 308 IDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGT 367 +D+E+ SYEI ++ +DK PLSGHC+V+V++ D NDN P++ +L LP++EDAPL T Sbjct: 307 LDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLST 366 Query: 368 VIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427 VIALISVSD+D G NG VTCSL HVPFKLVSTFKNYYSLVLDSALDRESVS YELVVTA Sbjct: 367 VIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTA 426 Query: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQEN 487 RDGGSPSLWATASVSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQEN Sbjct: 427 RDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQEN 486 Query: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGS 547 ALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQV+ARDAGVPPLGS Sbjct: 487 ALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGS 546 Query: 548 NVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWL 607 NVTLQVFVLDENDNAPALL PR GGTGGAVSELVP SVG GHVVAKVRAVD DSGYNAWL Sbjct: 547 NVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWL 606 Query: 608 SYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLV 667 SYELQP G ARIPFRVGLYTGEISTTR+LDET+APRHRLLVLVKDHGEP LTATATVLV Sbjct: 607 SYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLV 666 Query: 668 SLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALP 727 SLVESGQAPKASSRA GAVGP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA P Sbjct: 667 SLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQP 726 Query: 728 TEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQL 786 TE C GKPTL+CSSAVGSWSYSQQRR RVCSGE PPKTDLMAFSPSLP D + Sbjct: 727 TEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTDNV 785 >gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] Length = 936 Score = 1228 bits (3177), Expect = 0.0 Identities = 631/777 (81%), Positives = 677/777 (87%) Query: 8 GQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 G RLLLL LLLA W+AG+GQLHYS+ EEAKHGTFVGRIAQDLGLELAELVPRLFRVA Sbjct: 7 GSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 66 Query: 68 SKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127 SKGRG LLEVNLQNGILFVNSRIDREELCRR AECSIHLEVIVDRPLQVFHV+V V+DIN Sbjct: 67 SKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDIN 126 Query: 128 DNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDE 187 DNPP F ++ L I ESR DSRFPLEGASD DIG NA L YRL+PNEYF L+ ++E Sbjct: 127 DNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEE 186 Query: 188 LVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIY 247 L L+LRKSLDREE E L++ ATDGGKPELTGTVQLLI VLDANDNAP FD++IY Sbjct: 187 ETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIY 246 Query: 248 KVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGY 307 VRLLEN P+GTLVIKLNASD DEG+N +IVY FSN + +VKSKF I+ TG+I V G Sbjct: 247 NVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGE 306 Query: 308 IDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGT 367 +D+E+ SYEI ++ +DK PLSGHC+V+V++ D NDN P++ +L LP++EDAPL T Sbjct: 307 LDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLST 366 Query: 368 VIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427 VIALISVSD+D G NG VTCSL HVPFKLVSTFKNYYSLVLDSALDRESVS YELVVTA Sbjct: 367 VIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTA 426 Query: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQEN 487 RDGGSPSLWATASVSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQEN Sbjct: 427 RDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQEN 486 Query: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGS 547 ALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQV+ARDAGVPPLGS Sbjct: 487 ALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGS 546 Query: 548 NVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWL 607 NVTLQVFVLDENDNAPALL PR GGTGGAVSELVP SVG GHVVAKVRAVD DSGYNAWL Sbjct: 547 NVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWL 606 Query: 608 SYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLV 667 SYELQP G ARIPFRVGLYTGEISTTR+LDET+APRHRLLVLVKDHGEP LTATATVLV Sbjct: 607 SYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLV 666 Query: 668 SLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALP 727 SLVESGQAPKASSRA GAVGP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA P Sbjct: 667 SLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQP 726 Query: 728 TEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDRED 784 TE C GKPTL+CSSAVGSWSYSQQRR RVCSGE PPKTDLMAFSPSLP D Sbjct: 727 TEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTD 783 >gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapiens] Length = 803 Score = 1212 bits (3135), Expect = 0.0 Identities = 623/787 (79%), Positives = 680/787 (86%), Gaps = 3/787 (0%) Query: 14 LLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGG 73 LLL LLLLAAW+ G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK R Sbjct: 14 LLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDRED 73 Query: 74 LLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVF 133 LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP+F Sbjct: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLF 133 Query: 134 PATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLG 193 P ++ + I ESR DS FPLEGASDAD+G N++LTY+LS +EYF L+ + + K +G Sbjct: 134 PVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIG 193 Query: 194 LILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLE 253 L+L+KSLDREEAP L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y+VR+ E Sbjct: 194 LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFE 253 Query: 254 NVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEES 313 N NGT VI+LNASD DEG NG I YSF++ ++ V F ID TG+I+++G +DFE+ Sbjct: 254 NADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQE 313 Query: 314 KSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALIS 373 Y+I+++ DKG P++GHC V+V + D NDNVP++ SLSLP+REDA GTVIALIS Sbjct: 314 NLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALIS 373 Query: 374 VSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433 V+D D G NG V CSLT HVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP Sbjct: 374 VNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433 Query: 434 SLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 493 SLWATAS+SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENALVSYS Sbjct: 434 SLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493 Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQV 553 LVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLGSNVTLQV Sbjct: 494 LVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553 Query: 554 FVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQP 613 FVLDENDNAPALLAPR GGTGGAVSELVP S+G G VVAKVRAVDADSGYNAWLSYELQP Sbjct: 554 FVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQP 613 Query: 614 GTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESG 673 AR PFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEPALTATATVLVSLVESG Sbjct: 614 PASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESG 673 Query: 674 QAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACA 733 QAPKASSRA VGA GP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PTEGAC Sbjct: 674 QAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACT 733 Query: 734 PGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSL---PDSRDREDQLQTTE 790 KPTLVCSSAVGSWSYSQQRR RVCSGEGPPK DLMAFSPSL P + + E Sbjct: 734 ADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDLNE 793 Query: 791 ESFAKVS 797 + AKVS Sbjct: 794 DHDAKVS 800 >gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapiens] Length = 807 Score = 1210 bits (3130), Expect = 0.0 Identities = 623/790 (78%), Positives = 681/790 (86%) Query: 1 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 M FS G +R LLL LLLLAAWE G+GQLHYS+ EEAKHGTFVGR+AQDLGLELAELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 61 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASK LLEVNLQNGILFVNSRIDREELC+ SAECSIHLE+I DRPLQVFHV+ Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180 V+V+DINDNPPVF ++ + I ESR L+SRFP+EGA+DADIG NALLTY LSP++YFSL Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240 + DEL K L L LRK LDREE PE+ L+LTATDGGKPEL GTV+LLITVLD NDNAP Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300 FD+ +Y+V LLE NGTLV LNASD DEG+NG++V+SF + IS +++ KF +D +G Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360 +I + +D+EE+KSYEI V+ +DKG P+S HC+V+V+V D NDN P+L SL LPIR Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 EDAPL TVIALI+VSD+D G NG VTCSL HVPFKLVSTFKNYYSLVLDSALDRES+S Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540 DADAQENALVSYSLVERRVGERALS+YVSVHAESGKVYALQPLDHEELELLQFQV+ARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLAPR GGT GAVSELVP VG GHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQP GGARIPFRVGLYTGEISTTR LDE D R+RLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSRA VG GP+AALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSR 780 LRCS PTEGA PGKPTLVCSSA+GSWS SQQRR RVCS EGPPKTDLMAFSP L S Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780 Query: 781 DREDQLQTTE 790 + ++ + E Sbjct: 781 NTSERNEQPE 790 >gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1210 bits (3130), Expect = 0.0 Identities = 623/790 (78%), Positives = 681/790 (86%) Query: 1 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 M FS G +R LLL LLLLAAWE G+GQLHYS+ EEAKHGTFVGR+AQDLGLELAELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 61 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASK LLEVNLQNGILFVNSRIDREELC+ SAECSIHLE+I DRPLQVFHV+ Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180 V+V+DINDNPPVF ++ + I ESR L+SRFP+EGA+DADIG NALLTY LSP++YFSL Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240 + DEL K L L LRK LDREE PE+ L+LTATDGGKPEL GTV+LLITVLD NDNAP Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300 FD+ +Y+V LLE NGTLV LNASD DEG+NG++V+SF + IS +++ KF +D +G Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360 +I + +D+EE+KSYEI V+ +DKG P+S HC+V+V+V D NDN P+L SL LPIR Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 EDAPL TVIALI+VSD+D G NG VTCSL HVPFKLVSTFKNYYSLVLDSALDRES+S Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540 DADAQENALVSYSLVERRVGERALS+YVSVHAESGKVYALQPLDHEELELLQFQV+ARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLAPR GGT GAVSELVP VG GHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQP GGARIPFRVGLYTGEISTTR LDE D R+RLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSRA VG GP+AALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSR 780 LRCS PTEGA PGKPTLVCSSA+GSWS SQQRR RVCS EGPPKTDLMAFSP L S Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780 Query: 781 DREDQLQTTE 790 + ++ + E Sbjct: 781 NTSERNEQPE 790 >gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1209 bits (3128), Expect = 0.0 Identities = 617/763 (80%), Positives = 671/763 (87%) Query: 14 LLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGG 73 LLL LLLLAAW+ G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK R Sbjct: 14 LLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDRED 73 Query: 74 LLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVF 133 LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP+F Sbjct: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLF 133 Query: 134 PATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLG 193 P ++ + I ESR DS FPLEGASDAD+G N++LTY+LS +EYF L+ + + K +G Sbjct: 134 PVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIG 193 Query: 194 LILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLE 253 L+L+KSLDREEAP L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y+VR+ E Sbjct: 194 LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFE 253 Query: 254 NVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEES 313 N NGT VI+LNASD DEG NG I YSF++ ++ V F ID TG+I+++G +DFE+ Sbjct: 254 NADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQE 313 Query: 314 KSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALIS 373 Y+I+++ DKG P++GHC V+V + D NDNVP++ SLSLP+REDA GTVIALIS Sbjct: 314 NLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALIS 373 Query: 374 VSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433 V+D D G NG V CSLT HVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP Sbjct: 374 VNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433 Query: 434 SLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 493 SLWATAS+SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENALVSYS Sbjct: 434 SLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493 Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQV 553 LVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLGSNVTLQV Sbjct: 494 LVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553 Query: 554 FVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQP 613 FVLDENDNAPALLAPR GGTGGAVSELVP S+G G VVAKVRAVDADSGYNAWLSYELQP Sbjct: 554 FVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQP 613 Query: 614 GTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESG 673 AR PFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEPALTATATVLVSLVESG Sbjct: 614 PASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESG 673 Query: 674 QAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACA 733 QAPKASSRA VGA GP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PTEGAC Sbjct: 674 QAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACT 733 Query: 734 PGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSL 776 KPTLVCSSAVGSWSYSQQRR RVCSGEGPPK DLMAFSPSL Sbjct: 734 ADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSL 776 >gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapiens] Length = 814 Score = 1206 bits (3121), Expect = 0.0 Identities = 614/777 (79%), Positives = 671/777 (86%) Query: 1 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 M++ W S RLLLLLLLLAAW+ G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASK LLEV+LQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVD Sbjct: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180 VEV+D+NDNPPVF + L ++ESR DSRFPLEGASDAD+G N++LTYRLS ++YF L Sbjct: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 Query: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240 + ++ K + L+LRKSLDRE+AP L LTATDGGKPELTGTVQLL+TVLD NDNAP Sbjct: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300 F+++ Y+VR+ EN NGT VIKLNASD DEG NG I YSF++ + V F ID TG Sbjct: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 Query: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360 +I+++G +DFE+ Y+I+++ DKG P++GHC V+V + D NDNVP++ SLSLP+R Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 EDA GTVIALISV+D D G NG VTCSL HVPFKLVSTFKNYYSLVLDSALDRE VSA Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWATAS+SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540 DADAQENALVSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQV+ARDA Sbjct: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR GGTGGA S+LVP SVG GHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQP RIPFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSR G +GP+AALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLP 777 LRCSALPTEG C GKPTLVCSSAVGSWSYSQQ+ RVCSGEGPPKTDLMAFSP LP Sbjct: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLP 777 >gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1206 bits (3121), Expect = 0.0 Identities = 614/777 (79%), Positives = 671/777 (86%) Query: 1 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 M++ W S RLLLLLLLLAAW+ G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASK LLEV+LQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVD Sbjct: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180 VEV+D+NDNPPVF + L ++ESR DSRFPLEGASDAD+G N++LTYRLS ++YF L Sbjct: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 Query: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240 + ++ K + L+LRKSLDRE+AP L LTATDGGKPELTGTVQLL+TVLD NDNAP Sbjct: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300 F+++ Y+VR+ EN NGT VIKLNASD DEG NG I YSF++ + V F ID TG Sbjct: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 Query: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360 +I+++G +DFE+ Y+I+++ DKG P++GHC V+V + D NDNVP++ SLSLP+R Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 EDA GTVIALISV+D D G NG VTCSL HVPFKLVSTFKNYYSLVLDSALDRE VSA Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWATAS+SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540 DADAQENALVSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQV+ARDA Sbjct: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR GGTGGA S+LVP SVG GHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQP RIPFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSR G +GP+AALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLP 777 LRCSALPTEG C GKPTLVCSSAVGSWSYSQQ+ RVCSGEGPPKTDLMAFSP LP Sbjct: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLP 777 >gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sapiens] Length = 810 Score = 1201 bits (3107), Expect = 0.0 Identities = 620/783 (79%), Positives = 678/783 (86%), Gaps = 1/783 (0%) Query: 8 GQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 G + RL L LLLL WE G+GQLHYSVSEEAKHGTFVGRIAQDLGLELAELV RLFRVA Sbjct: 8 GLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVA 67 Query: 68 SKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127 SK G LLEVNLQNGILFVNSRIDREELC +SAECSIHLEVIVDRPLQVFHV+VEV+DIN Sbjct: 68 SKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDIN 127 Query: 128 DNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDE 187 DNPPVF ++ L IAES+ DSRFPLEGASDADI ENALLTYRLS NEYFSL+ P + + Sbjct: 128 DNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGK 187 Query: 188 LVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIY 247 +K L LIL+KSLDRE+ PE+ L+LTATDGGKPELTGTV+LL+ VLD NDN P FD++ Y Sbjct: 188 QIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEY 247 Query: 248 KVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGY 307 KV L+EN TLV+KLNA+D DEG+NG++ YS + I PN + F +D G++ V G Sbjct: 248 KVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGT 306 Query: 308 IDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGT 367 +D+EE+K Y+I V+ DKG P++GHC V VE+ D NDN P++ SLSLP+REDA T Sbjct: 307 LDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPST 366 Query: 368 VIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427 VIALISVSD+D GVNG VTCSLT HVPFKLVSTFKNYYSLVLDSALDRE+V AYELVVTA Sbjct: 367 VIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTA 426 Query: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQEN 487 RDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQEN Sbjct: 427 RDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQEN 486 Query: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGS 547 ALVSYSLVERR+G+RALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPL S Sbjct: 487 ALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSS 546 Query: 548 NVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWL 607 NVTLQVFVLDENDNAPALLA +AG GGAV++LVP SVG GHVVAKVRAVDADSGYNAWL Sbjct: 547 NVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWL 606 Query: 608 SYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLV 667 SYELQP GG+RIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEPALTATATVLV Sbjct: 607 SYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLV 666 Query: 668 SLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALP 727 SLVESGQAPKASSR L GA P+AALVDVNVYLIIAIC VSSLLVLTLLLYTAL SA P Sbjct: 667 SLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATP 726 Query: 728 TEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQLQ 787 TEGACAPGKPTLVCS AVGSWSYSQQRR RVCS EGPPKTDLMAFSPSLP ++E++ + Sbjct: 727 TEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEEGE 786 Query: 788 TTE 790 E Sbjct: 787 RQE 789 >gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapiens] Length = 949 Score = 1201 bits (3107), Expect = 0.0 Identities = 620/783 (79%), Positives = 678/783 (86%), Gaps = 1/783 (0%) Query: 8 GQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 G + RL L LLLL WE G+GQLHYSVSEEAKHGTFVGRIAQDLGLELAELV RLFRVA Sbjct: 8 GLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVA 67 Query: 68 SKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127 SK G LLEVNLQNGILFVNSRIDREELC +SAECSIHLEVIVDRPLQVFHV+VEV+DIN Sbjct: 68 SKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDIN 127 Query: 128 DNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDE 187 DNPPVF ++ L IAES+ DSRFPLEGASDADI ENALLTYRLS NEYFSL+ P + + Sbjct: 128 DNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGK 187 Query: 188 LVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIY 247 +K L LIL+KSLDRE+ PE+ L+LTATDGGKPELTGTV+LL+ VLD NDN P FD++ Y Sbjct: 188 QIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEY 247 Query: 248 KVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGY 307 KV L+EN TLV+KLNA+D DEG+NG++ YS + I PN + F +D G++ V G Sbjct: 248 KVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGT 306 Query: 308 IDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGT 367 +D+EE+K Y+I V+ DKG P++GHC V VE+ D NDN P++ SLSLP+REDA T Sbjct: 307 LDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPST 366 Query: 368 VIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427 VIALISVSD+D GVNG VTCSLT HVPFKLVSTFKNYYSLVLDSALDRE+V AYELVVTA Sbjct: 367 VIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTA 426 Query: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQEN 487 RDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQEN Sbjct: 427 RDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQEN 486 Query: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGS 547 ALVSYSLVERR+G+RALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPL S Sbjct: 487 ALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSS 546 Query: 548 NVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWL 607 NVTLQVFVLDENDNAPALLA +AG GGAV++LVP SVG GHVVAKVRAVDADSGYNAWL Sbjct: 547 NVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWL 606 Query: 608 SYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLV 667 SYELQP GG+RIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEPALTATATVLV Sbjct: 607 SYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLV 666 Query: 668 SLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALP 727 SLVESGQAPKASSR L GA P+AALVDVNVYLIIAIC VSSLLVLTLLLYTAL SA P Sbjct: 667 SLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATP 726 Query: 728 TEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQLQ 787 TEGACAPGKPTLVCS AVGSWSYSQQRR RVCS EGPPKTDLMAFSPSLP ++E++ + Sbjct: 727 TEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEEGE 786 Query: 788 TTE 790 E Sbjct: 787 RQE 789 >gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sapiens] Length = 844 Score = 1184 bits (3064), Expect = 0.0 Identities = 620/776 (79%), Positives = 668/776 (86%), Gaps = 5/776 (0%) Query: 14 LLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGG 73 LLL LLLLAAWE G+GQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVASK G Sbjct: 13 LLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRHGD 72 Query: 74 LLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVF 133 LLEVNLQNGILFVNSRIDREELC RS ECSIHLEVIVDRPLQVFHVDVEV+DINDNPP F Sbjct: 73 LLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPPRF 132 Query: 134 PATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLG 193 T++ LSI ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF L+ + K Sbjct: 133 SVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKFPV 192 Query: 194 LILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLE 253 L+LRK LDREE P++ L+LTATDGGKPE TG+V LLI VLDANDNAP FDR +Y+V++ E Sbjct: 193 LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKMYE 252 Query: 254 NVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEES 313 N N TLVI+LNASD DEG+N +++YSFS+ + P ++ KF I+ TG+I V IDFE+S Sbjct: 253 NQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFEDS 312 Query: 314 KSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALIS 373 +YEI V+ DKG P+ GHC V+VE+ D NDN P++ SLSLP++EDA +GTVIALIS Sbjct: 313 NTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIALIS 372 Query: 374 VSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433 VSD D G NG VTCSLT HVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARDGGSP Sbjct: 373 VSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGGSP 432 Query: 434 SLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 493 LWATASVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS Sbjct: 433 PLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 492 Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQV 553 LVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARD GVPPLGSN+TLQV Sbjct: 493 LVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNLTLQV 552 Query: 554 FVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQP 613 FVLDENDNAPALLA AG GGAVSELV SV GHVVAKVRAVDADSGYNAWLSYELQ Sbjct: 553 FVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSYELQS 612 Query: 614 GTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESG 673 GARIPFRVGLYTGEISTTRALDETD+PR RLLVLVKDHGEP+LTATATVLVSLVE Sbjct: 613 AAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSLVEGS 672 Query: 674 QAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACA 733 QAPKASSRA VG V P+ ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PTEGAC Sbjct: 673 QAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTEGACG 731 Query: 734 PGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPD----SRDREDQ 785 P KPTLVCSSAVGSWSYSQQRR RVCSGEG PK DLMAFSPSLP D EDQ Sbjct: 732 PVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGEDQ 787 >gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapiens] Length = 948 Score = 1184 bits (3064), Expect = 0.0 Identities = 620/776 (79%), Positives = 668/776 (86%), Gaps = 5/776 (0%) Query: 14 LLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGG 73 LLL LLLLAAWE G+GQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVASK G Sbjct: 13 LLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRHGD 72 Query: 74 LLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVF 133 LLEVNLQNGILFVNSRIDREELC RS ECSIHLEVIVDRPLQVFHVDVEV+DINDNPP F Sbjct: 73 LLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPPRF 132 Query: 134 PATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLG 193 T++ LSI ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF L+ + K Sbjct: 133 SVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKFPV 192 Query: 194 LILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLE 253 L+LRK LDREE P++ L+LTATDGGKPE TG+V LLI VLDANDNAP FDR +Y+V++ E Sbjct: 193 LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKMYE 252 Query: 254 NVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEES 313 N N TLVI+LNASD DEG+N +++YSFS+ + P ++ KF I+ TG+I V IDFE+S Sbjct: 253 NQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFEDS 312 Query: 314 KSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALIS 373 +YEI V+ DKG P+ GHC V+VE+ D NDN P++ SLSLP++EDA +GTVIALIS Sbjct: 313 NTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIALIS 372 Query: 374 VSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433 VSD D G NG VTCSLT HVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARDGGSP Sbjct: 373 VSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGGSP 432 Query: 434 SLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 493 LWATASVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS Sbjct: 433 PLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 492 Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQV 553 LVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARD GVPPLGSN+TLQV Sbjct: 493 LVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNLTLQV 552 Query: 554 FVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQP 613 FVLDENDNAPALLA AG GGAVSELV SV GHVVAKVRAVDADSGYNAWLSYELQ Sbjct: 553 FVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSYELQS 612 Query: 614 GTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESG 673 GARIPFRVGLYTGEISTTRALDETD+PR RLLVLVKDHGEP+LTATATVLVSLVE Sbjct: 613 AAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSLVEGS 672 Query: 674 QAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACA 733 QAPKASSRA VG V P+ ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PTEGAC Sbjct: 673 QAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTEGACG 731 Query: 734 PGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPD----SRDREDQ 785 P KPTLVCSSAVGSWSYSQQRR RVCSGEG PK DLMAFSPSLP D EDQ Sbjct: 732 PVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGEDQ 787 >gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sapiens] Length = 792 Score = 1180 bits (3053), Expect = 0.0 Identities = 617/775 (79%), Positives = 665/775 (85%), Gaps = 2/775 (0%) Query: 8 GQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 G S+RLLL LLLLAAWE G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVA Sbjct: 8 GPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 Query: 68 SKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127 SK G LLEVNLQNGILFVNSRIDRE+LC RSAECSIHLEVIVDRPLQVFHVDVEV+DIN Sbjct: 68 SKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127 Query: 128 DNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLE-KPPDD 186 DNPPVF ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L+ K D Sbjct: 128 DNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKD 187 Query: 187 ELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTI 246 + + L+LRK LDRE+ P++ L+L DGGKPELTG+VQ+ ITVLD NDN PAFD+ Sbjct: 188 KSILP-ELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPS 246 Query: 247 YKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKG 306 YKV L ENV N T VI+LNASD DEGLNG+I Y + + K F I+P TG+I + G Sbjct: 247 YKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYG 306 Query: 307 YIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLG 366 +DFEE+ +YEI V IDKG ++GH V+VEV D NDNVP++ SLSLP++EDA +G Sbjct: 307 ELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVG 366 Query: 367 TVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVT 426 TVIALISVSD+D G NG V CSLT HVPFKLVST+KNYYSLVLDSALDRESVSAYELVVT Sbjct: 367 TVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426 Query: 427 ARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQE 486 ARDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ+ Sbjct: 427 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQK 486 Query: 487 NALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLG 546 NALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLG Sbjct: 487 NALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLG 546 Query: 547 SNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAW 606 SNVTLQVFVLDENDNAPALLA AG GGAVSELVP SVG GHVVAKVRAVDADSGYNAW Sbjct: 547 SNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAW 606 Query: 607 LSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVL 666 LSYELQP GA IPF VGLYTGEISTTR LDE DAPRHRLLVLVKDHGEPALT+TATVL Sbjct: 607 LSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVL 666 Query: 667 VSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAL 726 VSLVE+GQAPK SSRA VGAV P+AALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSA Sbjct: 667 VSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAP 726 Query: 727 PTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRD 781 PT CAPGKPTLVCSSAVGSWSYSQQRR RVCS E PPKTDLMAFSPSL SR+ Sbjct: 727 PTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSRE 781 >gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapiens] Length = 941 Score = 1180 bits (3053), Expect = 0.0 Identities = 617/775 (79%), Positives = 665/775 (85%), Gaps = 2/775 (0%) Query: 8 GQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 G S+RLLL LLLLAAWE G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVA Sbjct: 8 GPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 Query: 68 SKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127 SK G LLEVNLQNGILFVNSRIDRE+LC RSAECSIHLEVIVDRPLQVFHVDVEV+DIN Sbjct: 68 SKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127 Query: 128 DNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLE-KPPDD 186 DNPPVF ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L+ K D Sbjct: 128 DNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKD 187 Query: 187 ELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTI 246 + + L+LRK LDRE+ P++ L+L DGGKPELTG+VQ+ ITVLD NDN PAFD+ Sbjct: 188 KSILP-ELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPS 246 Query: 247 YKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKG 306 YKV L ENV N T VI+LNASD DEGLNG+I Y + + K F I+P TG+I + G Sbjct: 247 YKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYG 306 Query: 307 YIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLG 366 +DFEE+ +YEI V IDKG ++GH V+VEV D NDNVP++ SLSLP++EDA +G Sbjct: 307 ELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVG 366 Query: 367 TVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVT 426 TVIALISVSD+D G NG V CSLT HVPFKLVST+KNYYSLVLDSALDRESVSAYELVVT Sbjct: 367 TVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426 Query: 427 ARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQE 486 ARDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ+ Sbjct: 427 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQK 486 Query: 487 NALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLG 546 NALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLG Sbjct: 487 NALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLG 546 Query: 547 SNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAW 606 SNVTLQVFVLDENDNAPALLA AG GGAVSELVP SVG GHVVAKVRAVDADSGYNAW Sbjct: 547 SNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAW 606 Query: 607 LSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVL 666 LSYELQP GA IPF VGLYTGEISTTR LDE DAPRHRLLVLVKDHGEPALT+TATVL Sbjct: 607 LSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVL 666 Query: 667 VSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAL 726 VSLVE+GQAPK SSRA VGAV P+AALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSA Sbjct: 667 VSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAP 726 Query: 727 PTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRD 781 PT CAPGKPTLVCSSAVGSWSYSQQRR RVCS E PPKTDLMAFSPSL SR+ Sbjct: 727 PTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSRE 781 >gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapiens] Length = 686 Score = 793 bits (2049), Expect = 0.0 Identities = 405/534 (75%), Positives = 455/534 (85%) Query: 1 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 M FS G +R LLL LLLLAAWE G+GQLHYS+ EEAKHGTFVGR+AQDLGLELAELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 61 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASK LLEVNLQNGILFVNSRIDREELC+ SAECSIHLE+I DRPLQVFHV+ Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180 V+V+DINDNPPVF ++ + I ESR L+SRFP+EGA+DADIG NALLTY LSP++YFSL Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240 + DEL K L L LRK LDREE PE+ L+LTATDGGKPEL GTV+LLITVLD NDNAP Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300 FD+ +Y+V LLE NGTLV LNASD DEG+NG++V+SF + IS +++ KF +D +G Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360 +I + +D+EE+KSYEI V+ +DKG P+S HC+V+V+V D NDN P+L SL LPIR Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 EDAPL TVIALI+VSD+D G NG VTCSL HVPFKLVSTFKNYYSLVLDSALDRES+S Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534 DADAQENALVSYSLVERRVGERALS+YVSVHAESGKVYALQPLDHEELELLQFQ Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQ 534 Score = 145 bits (366), Expect = 1e-34 Identities = 130/405 (32%), Positives = 185/405 (45%), Gaps = 45/405 (11%) Query: 289 VKSKFHIDPI-----TGQIIVKGYIDFEE----SKSYEIIVEGIDKGQLPLSGHCRVIVE 339 V SK H D + G + V ID EE S I +E I L + V V+ Sbjct: 66 VASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVF---HVEVK 122 Query: 340 VEDNNDNVPDLEFKSLSLPIREDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVS 399 V+D NDN P + + I E L + + +D D+G N L+T +L+ F L Sbjct: 123 VKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDV 182 Query: 400 TFKNYYS----LVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAF 455 + S L L LDRE L++TA DGG P L T + + V DVNDNAP F Sbjct: 183 EASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLF 242 Query: 456 AQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL---VERRVGERALSSYVSVHA 512 Q Y V + E G + T++A DAD N V +S + R + E+ V + Sbjct: 243 DQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEK-----FKVDS 297 Query: 513 ESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGG 572 SG++ + LD+EE + + QV A D G PP+ ++ + V VLD NDNAP L Sbjct: 298 SSGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPEL------- 350 Query: 573 TGGAVSEL---VPWSVGVGHVVAKVRAVDADSGYNAWLSYELQPGTGGARIPFR-VGLYT 628 AV+ L + + V+A + D DSG N ++ L P +PF+ V + Sbjct: 351 ---AVTSLYLPIREDAPLSTVIALITVSDRDSGANGQVTCSLMP-----HVPFKLVSTFK 402 Query: 629 GEISTT--RALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVE 671 S ALD + L+V +D G P+L ATA V V + + Sbjct: 403 NYYSLVLDSALDRESLSVYELVVTARDGGSPSLWATARVSVEVAD 447 Score = 138 bits (348), Expect = 2e-32 Identities = 133/467 (28%), Positives = 203/467 (43%), Gaps = 21/467 (4%) Query: 230 ITVLDANDNAPAFDRTIYKVRLLEN-VPNGTLVIKLNASDLDEGLNGDIVYSFSND--IS 286 + V D NDN P F + + E+ + N I+ A+D D G N + Y+ S S Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIE-GAADADIGANALLTYTLSPSDYFS 179 Query: 287 PNVKSKFHIDPITGQIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDN 346 +V++ + + ++ Y+D EE+ +++ D G+ L G +++ V D NDN Sbjct: 180 LDVEASDELSKSLW-LELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDN 238 Query: 347 VPDLEFKSLSLPIREDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYS 406 P + + + E GT++ ++ SD D GVNG V S S + + FK S Sbjct: 239 APLFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSS 298 Query: 407 ---LVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVF 463 + L LD E +YE+ V A D GSP + V V+V DVNDNAP A + Sbjct: 299 SGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLP 358 Query: 464 VKENNPPGCHIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPL 523 ++E+ P I ++ D D+ N V+ SL+ V + +S++ + ++ + L Sbjct: 359 IREDAPLSTVIALITVSDRDSGANGQVTCSLMPH-VPFKLVSTFKNYYS----LVLDSAL 413 Query: 524 DHEELELLQFQVTARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPW 583 D E L + + VTARD G P L + + V V D NDNAPA P + V Sbjct: 414 DRESLSVYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPE-------YTVFVKE 466 Query: 584 SVGVGHVVAKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAP 643 + G + V A DAD+ NA +SY L G R E AL D Sbjct: 467 NNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHE 526 Query: 644 RHRLLVLVKDHGEPALTATATVLVSLVESGQAPKASSRALVGAVGPD 690 LL P +A++ + S +A G GPD Sbjct: 527 ELELLQFQPRQPNPDWRYSASLRAGMHSSVHLEEAGI-LRAGPGGPD 572 >gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapiens] Length = 686 Score = 786 bits (2029), Expect = 0.0 Identities = 398/521 (76%), Positives = 448/521 (85%) Query: 14 LLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGG 73 LLL LLLLAAW+ G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK R Sbjct: 14 LLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDRED 73 Query: 74 LLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVF 133 LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP+F Sbjct: 74 LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLF 133 Query: 134 PATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLG 193 P ++ + I ESR DS FPLEGASDAD+G N++LTY+LS +EYF L+ + + K +G Sbjct: 134 PVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIG 193 Query: 194 LILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLE 253 L+L+KSLDREEAP L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y+VR+ E Sbjct: 194 LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFE 253 Query: 254 NVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEES 313 N NGT VI+LNASD DEG NG I YSF++ ++ V F ID TG+I+++G +DFE+ Sbjct: 254 NADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQE 313 Query: 314 KSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALIS 373 Y+I+++ DKG P++GHC V+V + D NDNVP++ SLSLP+REDA GTVIALIS Sbjct: 314 NLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALIS 373 Query: 374 VSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433 V+D D G NG V CSLT HVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP Sbjct: 374 VNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433 Query: 434 SLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 493 SLWATAS+SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENALVSYS Sbjct: 434 SLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493 Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534 LVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQ Sbjct: 494 LVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534 Score = 156 bits (394), Expect = 8e-38 Identities = 133/430 (30%), Positives = 196/430 (45%), Gaps = 30/430 (6%) Query: 253 ENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEE 312 E +GT V ++ A DL L ++V S + + ++ G + V ID EE Sbjct: 37 EEAKHGTFVGRI-AQDLGLEL-AELVPRLFRMASKDREDLLEVNLQNGILFVNSRIDREE 94 Query: 313 ----SKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTV 368 S I +E I L + V VEV D NDN P + + I E +V Sbjct: 95 LCGRSAECSIHLEVIVDRPLQVF---HVDVEVRDINDNPPLFPVEEQRVLIYESRLPDSV 151 Query: 369 IALISVSDKDMGVNGLVTCSLTSHVPF----KLVSTFKNYYSLVLDSALDRESVSAYELV 424 L SD D+G N ++T L+S F K+ S L+L +LDRE A+ L Sbjct: 152 FPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIGLLLKKSLDREEAPAHNLF 211 Query: 425 VTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADA 484 +TA DGG P L T + V V DVNDNAP F Q EY V + EN G + ++A D D Sbjct: 212 LTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDE 271 Query: 485 QENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPP 544 N +SYS + + + S+ +G++ LD E+ L + + A D G PP Sbjct: 272 GANGAISYSF--NSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPP 329 Query: 545 LGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYN 604 + + T+ V +LD+NDN P + ++S V G V+A + D DSG N Sbjct: 330 MAGHCTVLVRILDKNDNVPEIALT-------SLSLPVREDAQFGTVIALISVNDLDSGAN 382 Query: 605 AWLSYELQPGTGGARIPFR-VGLYTGEISTT--RALDETDAPRHRLLVLVKDHGEPALTA 661 ++ L P +PF+ V + S ALD + L+V +D G P+L A Sbjct: 383 GQVNCSLTP-----HVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWA 437 Query: 662 TATVLVSLVE 671 TA++ V + + Sbjct: 438 TASLSVEVAD 447 Score = 151 bits (381), Expect = 3e-36 Identities = 118/395 (29%), Positives = 189/395 (47%), Gaps = 18/395 (4%) Query: 230 ITVLDANDNAPAFDRTIYKVRLLEN-VPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPN 288 + V D NDN P F +V + E+ +P+ ++ ASD D G N + Y S+ Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLE-GASDADVGSNSILTYKLSSSEYFG 179 Query: 289 VKSKFHIDPITG-QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNV 347 + K + D +++K +D EE+ ++ + + D G+ L+G +++V V D NDN Sbjct: 180 LDVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNA 239 Query: 348 PDLEFKSLSLPIREDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTF---KNY 404 P E + I E+A GT + ++ SD+D G NG ++ S S V ++ F +N Sbjct: 240 PTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNT 299 Query: 405 YSLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFV 464 +V+ LD E + Y++++ A D G P + +V V + D NDN P A ++ V Sbjct: 300 GEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPV 359 Query: 465 KENNPPGCHIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLD 524 +E+ G I +S D D+ N V+ SL V + +S++ + ++ + LD Sbjct: 360 REDAQFGTVIALISVNDLDSGANGQVNCSLTPH-VPFKLVSTFKNYYS----LVLDSALD 414 Query: 525 HEELELLQFQVTARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWS 584 E + + VTARD G P L + +L V V D NDNAPA P + V + Sbjct: 415 RESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPE-------YTVFVKEN 467 Query: 585 VGVGHVVAKVRAVDADSGYNAWLSYELQPGTGGAR 619 G + V A DAD+ NA +SY L G R Sbjct: 468 NPPGCHIFTVSARDADAQENALVSYSLVERRVGER 502 >gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sapiens] Length = 685 Score = 785 bits (2028), Expect = 0.0 Identities = 404/521 (77%), Positives = 447/521 (85%) Query: 14 LLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGG 73 LLL LLLLAAWE G+GQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVASK G Sbjct: 13 LLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRHGD 72 Query: 74 LLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVF 133 LLEVNLQNGILFVNSRIDREELC RS ECSIHLEVIVDRPLQVFHVDVEV+DINDNPP F Sbjct: 73 LLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPPRF 132 Query: 134 PATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLG 193 T++ LSI ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF L+ + K Sbjct: 133 SVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKFPV 192 Query: 194 LILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLE 253 L+LRK LDREE P++ L+LTATDGGKPE TG+V LLI VLDANDNAP FDR +Y+V++ E Sbjct: 193 LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKMYE 252 Query: 254 NVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEES 313 N N TLVI+LNASD DEG+N +++YSFS+ + P ++ KF I+ TG+I V IDFE+S Sbjct: 253 NQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFEDS 312 Query: 314 KSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALIS 373 +YEI V+ DKG P+ GHC V+VE+ D NDN P++ SLSLP++EDA +GTVIALIS Sbjct: 313 NTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIALIS 372 Query: 374 VSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433 VSD D G NG VTCSLT HVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARDGGSP Sbjct: 373 VSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGGSP 432 Query: 434 SLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 493 LWATASVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS Sbjct: 433 PLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 492 Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534 LVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQ Sbjct: 493 LVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533 Score = 138 bits (348), Expect = 2e-32 Identities = 108/343 (31%), Positives = 159/343 (46%), Gaps = 21/343 (6%) Query: 336 VIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPF 395 V VEV+D NDN P L I E L + L SD D+G N L+T L+ + F Sbjct: 118 VDVEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYF 177 Query: 396 KLVSTFKN----YYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDN 451 L K + LVL LDRE +L++TA DGG P + S+ + V D NDN Sbjct: 178 VLDIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDN 237 Query: 452 APAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVH 511 AP F +P Y V + EN + ++A D+D N + YS + + ++ Sbjct: 238 APIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSS--LVPPTIRRKFWIN 295 Query: 512 AESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAG 571 +G++ +D E+ + V D G PP+ + T+ V +LDENDN+P ++ Sbjct: 296 ERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVT--- 352 Query: 572 GTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQPGTGGARIPFR-VGLYTGE 630 ++S V VG V+A + D DSG N ++ L P +PF+ V Y Sbjct: 353 ----SLSLPVKEDAQVGTVIALISVSDHDSGANGQVTCSLTP-----HVPFKLVSTYKNY 403 Query: 631 ISTT--RALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVE 671 S ALD + L+V +D G P L ATA+V V + + Sbjct: 404 YSLVLDSALDRERVSAYELVVTARDGGSPPLWATASVSVEVAD 446 Score = 134 bits (336), Expect = 4e-31 Identities = 111/392 (28%), Positives = 182/392 (46%), Gaps = 28/392 (7%) Query: 230 ITVLDANDNAPAFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSND----- 284 + V D NDN P F T K+ + E+ + ASD D G N + Y S + Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVL 179 Query: 285 --ISPNVKSKFHIDPITGQIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVED 342 I+ K KF + ++++ +D EE+ ++++ D G+ +G +++ V D Sbjct: 180 DIINKKDKDKFPV------LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLD 233 Query: 343 NNDNVPDLEFKSLSLPIREDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTF- 401 NDN P + + + E+ T++ ++ SD D G+N + S +S VP + F Sbjct: 234 ANDNAPIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFW 293 Query: 402 --KNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPE 459 + + ++ A+D E + YE+ V D G+P + +V VE+ D NDN+P Sbjct: 294 INERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTS 353 Query: 460 YTVFVKENNPPGCHIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYA 519 ++ VKE+ G I +S D D+ N V+ SL V + +S+Y + ++ + Sbjct: 354 LSLPVKEDAQVGTVIALISVSDHDSGANGQVTCSLTPH-VPFKLVSTYKNYYS----LVL 408 Query: 520 LQPLDHEELELLQFQVTARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSE 579 LD E + + VTARD G PPL + ++ V V D NDNAPA + Sbjct: 409 DSALDRERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAF-------AQSEYTV 461 Query: 580 LVPWSVGVGHVVAKVRAVDADSGYNAWLSYEL 611 V + G + V A DAD+ NA +SY L Sbjct: 462 FVKENNPPGCHIFTVSAWDADAQENALVSYSL 493 Score = 95.5 bits (236), Expect = 2e-19 Identities = 89/274 (32%), Positives = 124/274 (45%), Gaps = 23/274 (8%) Query: 441 VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSLVERRVG 500 V VEV D+NDN P F+ E + + E+ A DAD ENAL++Y L Sbjct: 118 VDVEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYF 177 Query: 501 ERALSSYVSVHAESGKVYALQPL-DHEELELLQFQVTARDAGVPPLGSNVTLQVFVLDEN 559 L + V L+ L D EE L+ +TA D G P +V+L + VLD N Sbjct: 178 --VLDIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDAN 235 Query: 560 DNAPALLAPRAGGTGGAVSELVPWSVGVGH-VVAKVRAVDADSGYNAWLSYE---LQPGT 615 DNAP P V E+ + V +V ++ A D+D G N + Y L P T Sbjct: 236 DNAPIFDRP--------VYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPT 287 Query: 616 GGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLV-ESGQ 674 R F + TGEI A+D D+ + + V V D G P + TVLV L+ E+ Sbjct: 288 --IRRKFWINERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDN 345 Query: 675 APKASSRALVGAVGPDAALVDVNVYLIIAICAVS 708 +P+ +L V DA V +IA+ +VS Sbjct: 346 SPEVIVTSLSLPVKEDA-----QVGTVIALISVS 374 >gi|14277677 protocadherin gamma subfamily C, 3 isoform 2 precursor [Homo sapiens] Length = 863 Score = 607 bits (1565), Expect = e-173 Identities = 314/713 (44%), Positives = 460/713 (64%), Gaps = 9/713 (1%) Query: 4 SWGSGQESR-RLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPR 62 +W SG S R++ +LLLL A + +HY + EE + G VG + +LGL+L L R Sbjct: 5 AWRSGLVSTGRVVGVLLLLGALNKASTVIHYEIPEEREKGFAVGNVVANLGLDLGSLSAR 64 Query: 63 LFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVE 122 FRV S EVN + G +FVN R+DREELC C++ LE++V+ PL++F V+V Sbjct: 65 RFRVVSGASRRFFEVNRETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSVEVV 124 Query: 123 VRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEK 182 ++DINDN P FP + L I+E+ +RFPLE A D D+G N+L TY LS NEYF+L Sbjct: 125 IQDINDNNPAFPTQEMKLEISEAVAPGTRFPLESAHDPDVGSNSLQTYELSRNEYFALRV 184 Query: 183 PPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAF 242 ++ K L+L ++LDRE P + LVLTA DGG P L+ ++ + I VLDANDNAP F Sbjct: 185 QTREDSTKYAELVLERALDREREPSLQLVLTALDGGTPALSASLPIHIKVLDANDNAPVF 244 Query: 243 DRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQI 302 ++++Y+ R+LE+ P+GT V+++ A+DLDEG NG+I+YSF + V+ F +D +TG + Sbjct: 245 NQSLYRARVLEDAPSGTRVVQVLATDLDEGPNGEIIYSFGSHNRAGVRQLFALDLVTGML 304 Query: 303 IVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIRED 362 +KG +DFE++K +EI ++ DKG P HC+V+VEV D NDN P++ S+ P+ ED Sbjct: 305 TIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPED 364 Query: 363 APLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYE 422 APLGTVIAL+SV+D D G NGLVTC + +PF L S+ KNY++L + LDRE+V Y Sbjct: 365 APLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSADLDRETVPEYN 424 Query: 423 LVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDA 482 L +TARD G+PSL A V V+V+D+NDN P +Q Y V+++ENN PG I +S WD Sbjct: 425 LSITARDAGTPSLSALTIVRVQVSDINDNPPQSSQSSYDVYIEENNLPGAPILNLSVWDP 484 Query: 483 DAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGV 542 DA +NA +S+ L+E+ + Y +++ ++G V +L PLD+E+ + D G Sbjct: 485 DAPQNARLSFFLLEQGAETGLVGRYFTINRDNGIVSSLVPLDYEDRREFELTAHISDGGT 544 Query: 543 PPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSG 602 P L +N+++ +FV D NDNAP +L PR GG+ E++P GH+V++V DAD+G Sbjct: 545 PVLATNISVNIFVTDRNDNAPQVLYPRPGGSS---VEMLPRGTSAGHLVSRVVGWDADAG 601 Query: 603 YNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTAT 662 +NAWLSY L + F +GL+TG+IST R + +TD+PR L VL+KD+GEP+L+ T Sbjct: 602 HNAWLSYSLLGSPNQSL--FAIGLHTGQISTARPVQDTDSPRQTLTVLIKDNGEPSLSTT 659 Query: 663 ATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTL 715 AT+ VS+ E +P+A + G+ P ++ YL++++ VS V+T+ Sbjct: 660 ATLTVSVTE--DSPEARAEFPSGS-APREQKKNLTFYLLLSLILVSVGFVVTV 709 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.134 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,256,175 Number of Sequences: 37866 Number of extensions: 1458375 Number of successful extensions: 10157 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 188 Number of HSP's successfully gapped in prelim test: 20 Number of HSP's that attempted gapping in prelim test: 3166 Number of HSP's gapped (non-prelim): 676 length of query: 798 length of database: 18,247,518 effective HSP length: 110 effective length of query: 688 effective length of database: 14,082,258 effective search space: 9688593504 effective search space used: 9688593504 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.