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Search of human proteins with 98986459
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|98986459 jumonji domain containing 2A [Homo sapiens]
(1064 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|98986459 jumonji domain containing 2A [Homo sapiens] 2186 0.0
gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens] 1180 0.0
gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens] 1140 0.0
gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens] 867 0.0
gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens] 867 0.0
gi|45504380 jumonji domain containing 2B [Homo sapiens] 608 e-173
gi|39653317 jumonji domain containing 2D [Homo sapiens] 518 e-146
gi|169203160 PREDICTED: hypothetical protein [Homo sapiens] 502 e-142
gi|169203656 PREDICTED: hypothetical protein [Homo sapiens] 502 e-142
gi|169202387 PREDICTED: hypothetical protein [Homo sapiens] 502 e-142
gi|239744460 PREDICTED: hypothetical protein [Homo sapiens] 498 e-140
gi|239755681 PREDICTED: hypothetical protein [Homo sapiens] 498 e-140
gi|239750150 PREDICTED: hypothetical protein [Homo sapiens] 498 e-140
gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo sa... 144 4e-34
gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo sa... 144 4e-34
gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens] 137 4e-32
gi|169218173 PREDICTED: similar to Jumonji, AT rich interactive ... 137 4e-32
gi|226442963 jumonji, AT rich interactive domain 1C isoform 2 [H... 137 5e-32
gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [H... 137 5e-32
gi|226442991 jumonji, AT rich interactive domain 1D isoform 1 [H... 137 5e-32
gi|226443002 jumonji, AT rich interactive domain 1D isoform 3 [H... 136 9e-32
gi|33356560 jumonji, AT rich interactive domain 1D isoform 2 [Ho... 136 9e-32
gi|11321642 bromodomain containing protein 1 [Homo sapiens] 122 2e-27
gi|51173722 bromodomain and PHD finger-containing protein 1 isof... 121 4e-27
gi|51173720 bromodomain and PHD finger-containing protein 1 isof... 121 4e-27
gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapi... 108 3e-23
gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithora... 101 4e-21
gi|40556370 PHD finger protein 15 [Homo sapiens] 100 7e-21
gi|57546899 myeloid/lymphoid or mixed-lineage leukemia transloca... 100 1e-20
gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocat... 100 1e-20
>gi|98986459 jumonji domain containing 2A [Homo sapiens]
Length = 1064
Score = 2186 bits (5664), Expect = 0.0
Identities = 1064/1064 (100%), Positives = 1064/1064 (100%)
Query: 1 MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYD 60
MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYD
Sbjct: 1 MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYD 60
Query: 61 DIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERK 120
DIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERK
Sbjct: 61 DIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERK 120
Query: 121 YWKNLTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGM 180
YWKNLTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGM
Sbjct: 121 YWKNLTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGM 180
Query: 181 WKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRH 240
WKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRH
Sbjct: 181 WKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRH 240
Query: 241 KMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYG 300
KMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYG
Sbjct: 241 KMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYG 300
Query: 301 KQAVLCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLPTPEAAEFLKESELP 360
KQAVLCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLPTPEAAEFLKESELP
Sbjct: 301 KQAVLCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLPTPEAAEFLKESELP 360
Query: 361 PRAGNEEECPEEDMEGVEDGEEGDLKTSLAKHRIGTKRHRVCLEIPQEVSQSELFPKEDL 420
PRAGNEEECPEEDMEGVEDGEEGDLKTSLAKHRIGTKRHRVCLEIPQEVSQSELFPKEDL
Sbjct: 361 PRAGNEEECPEEDMEGVEDGEEGDLKTSLAKHRIGTKRHRVCLEIPQEVSQSELFPKEDL 420
Query: 421 SSEQYEMTECPAALAPVRPTHSSVRQVEDGLTFPDYSDSTEVKFEELKNVKLEEEDEEEE 480
SSEQYEMTECPAALAPVRPTHSSVRQVEDGLTFPDYSDSTEVKFEELKNVKLEEEDEEEE
Sbjct: 421 SSEQYEMTECPAALAPVRPTHSSVRQVEDGLTFPDYSDSTEVKFEELKNVKLEEEDEEEE 480
Query: 481 QAAAALDLSVNPASVGGRLVFSGSKKKSSSSLGSGSSRDSISSDSETSEPLSCRAQGQTG 540
QAAAALDLSVNPASVGGRLVFSGSKKKSSSSLGSGSSRDSISSDSETSEPLSCRAQGQTG
Sbjct: 481 QAAAALDLSVNPASVGGRLVFSGSKKKSSSSLGSGSSRDSISSDSETSEPLSCRAQGQTG 540
Query: 541 VLTVHSYAKGDGRVTVGEPCTRKKGSAARSFSERELAEVADEYMFSLEENKKSKGRRQPL 600
VLTVHSYAKGDGRVTVGEPCTRKKGSAARSFSERELAEVADEYMFSLEENKKSKGRRQPL
Sbjct: 541 VLTVHSYAKGDGRVTVGEPCTRKKGSAARSFSERELAEVADEYMFSLEENKKSKGRRQPL 600
Query: 601 SKLPRHHPLVLQECVSDDETSEQLTPEEEAEETEAWAKPLSQLWQNRPPNFEAEKEFNET 660
SKLPRHHPLVLQECVSDDETSEQLTPEEEAEETEAWAKPLSQLWQNRPPNFEAEKEFNET
Sbjct: 601 SKLPRHHPLVLQECVSDDETSEQLTPEEEAEETEAWAKPLSQLWQNRPPNFEAEKEFNET 660
Query: 661 MAQQAPHCAVCMIFQTYHQVEFGGFNQNCGNASDLAPQKQRTKPLIPEMCFTSTGCSTDI 720
MAQQAPHCAVCMIFQTYHQVEFGGFNQNCGNASDLAPQKQRTKPLIPEMCFTSTGCSTDI
Sbjct: 661 MAQQAPHCAVCMIFQTYHQVEFGGFNQNCGNASDLAPQKQRTKPLIPEMCFTSTGCSTDI 720
Query: 721 NLSTPYLEEDGTSILVSCKKCSVRVHASCYGVPPAKASEDWMCSRCSANALEEDCCLCSL 780
NLSTPYLEEDGTSILVSCKKCSVRVHASCYGVPPAKASEDWMCSRCSANALEEDCCLCSL
Sbjct: 721 NLSTPYLEEDGTSILVSCKKCSVRVHASCYGVPPAKASEDWMCSRCSANALEEDCCLCSL 780
Query: 781 RGGALQRANDDRWVHVSCAVAILEARFVNIAERSPVDVSKIPLPRFKLKCIFCKKRRKRT 840
RGGALQRANDDRWVHVSCAVAILEARFVNIAERSPVDVSKIPLPRFKLKCIFCKKRRKRT
Sbjct: 781 RGGALQRANDDRWVHVSCAVAILEARFVNIAERSPVDVSKIPLPRFKLKCIFCKKRRKRT 840
Query: 841 AGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHKIPNLERAKGALQSIT 900
AGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHKIPNLERAKGALQSIT
Sbjct: 841 AGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHKIPNLERAKGALQSIT 900
Query: 901 AGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGSFSDNLYPEDIVSQDCLQFGPPAEG 960
AGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGSFSDNLYPEDIVSQDCLQFGPPAEG
Sbjct: 901 AGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGSFSDNLYPEDIVSQDCLQFGPPAEG 960
Query: 961 EVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQLVVKRDDVYTLDEELPKRVKSRLSV 1020
EVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQLVVKRDDVYTLDEELPKRVKSRLSV
Sbjct: 961 EVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQLVVKRDDVYTLDEELPKRVKSRLSV 1020
Query: 1021 ASDMRFNEIFTEKEVKQEKKRQRVINSRYREDYIEPALYRAIME 1064
ASDMRFNEIFTEKEVKQEKKRQRVINSRYREDYIEPALYRAIME
Sbjct: 1021 ASDMRFNEIFTEKEVKQEKKRQRVINSRYREDYIEPALYRAIME 1064
>gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens]
Length = 1056
Score = 1180 bits (3053), Expect = 0.0
Identities = 596/1092 (54%), Positives = 758/1092 (69%), Gaps = 77/1092 (7%)
Query: 1 MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYD 60
+A LNPS +IMTF P+MEEFR F++Y+AY+ES+GAHRAGLAKV+PPKEWKPR YD
Sbjct: 3 VAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYD 62
Query: 61 DIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERK 120
DID+L+IPAPIQQ+VTGQSGLFTQYNIQKKAMTV+EFR++ANS KYCTPRY ++E+LERK
Sbjct: 63 DIDNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLERK 122
Query: 121 YWKNLTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGM 180
YWKNLTF PIYGAD+NG++Y++ VDEWNI RL T+LD+VE+E GI+IEGVNTPYLYFGM
Sbjct: 123 YWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGM 182
Query: 181 WKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRH 240
WKT+FAWHTEDMDLYSINYLHFGEPKSWY++PPEHGKRLERLA+GFFP S+Q C+AFLRH
Sbjct: 183 WKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRH 242
Query: 241 KMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYG 300
KMTLISP +LKKYGIPFDK+TQEAGEFMITFPYGYHAGFNHGFNCAESTNFAT RWI+YG
Sbjct: 243 KMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYG 302
Query: 301 KQAVLCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLP----TPEAAEFLKE 356
K A LC+CRKDMVKISMD+FVRKFQP+RY+LWK GKD IDHT P TPE +L+
Sbjct: 303 KVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWLQR 362
Query: 357 SELPPRAGNEEECPEEDMEGVEDGEEGDLKTSLAKHRIGTKRHRVCLEIPQEVSQSELFP 416
+A +C + + EE E+ EV +E+ P
Sbjct: 363 RRKVRKASRSFQCARSTSKRPKADEEE--------------------EVSDEVDGAEV-P 401
Query: 417 KEDLSSEQYEMTECPAALAPVRPTHSSVR--------QVEDGLTFPDYSDSTEVKFEELK 468
D ++ +++E A +R T +S QVE L SD ++
Sbjct: 402 NPDSVTDDLKVSEKSEAAVKLRNTEASSEEESSASRMQVEQNL-----SDHIKLSGNSCL 456
Query: 469 NVKLEEEDEEEEQAAAALDLSVNPASVGGRLVFSGSKKKSSSSLGSGSSRDSISSDSETS 528
+ + E+ + E+ A A SV S S+ S L SG + S SE S
Sbjct: 457 STSVTEDIKTEDDKAYAY-RSVPSIS---------SEADDSIPLSSGYEKPEKSDPSELS 506
Query: 529 ---EPLSCRAQGQT-GVLT------VHSYAKGDGRVTVGEPCTRKKGSAARSFSERELAE 578
P SC + ++ GVLT V S+ G + GE G SF +AE
Sbjct: 507 WPKSPESCSSVAESNGVLTEGEESDVESHGNG---LEPGEIPAVPSGE-RNSFKVPSIAE 562
Query: 579 VADEYMFSLEENKKSKGRRQPLSKLPRHHP--LVLQECVSDDETSEQLTPEEEAEETEAW 636
ENK SK R PLS+ P P LV Q+ SD+E E L+ EEE EETE+W
Sbjct: 563 ---------GENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEVLSIEEEVEETESW 613
Query: 637 AKPLSQLWQNRPPNFEAEKEFNETMAQQAPHCAVCMIFQTYHQVEFGGFNQNC---GNAS 693
AKPL LWQ + PNF AE+E+N T+A+ PHCA+C + YH+ + +
Sbjct: 614 AKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDSSNEENDARWETKLD 673
Query: 694 DLAPQKQRTKPLIPEMCFTSTGCSTDINLSTPYLEEDGTSILVSCKKCSVRVHASCYGVP 753
++ + +TKPLIPEMCF + + + + +LEEDGTS+L+SC KC VRVHASCYG+P
Sbjct: 674 EVVTSEGKTKPLIPEMCFIYSEENIEYSPPNAFLEEDGTSLLISCAKCCVRVHASCYGIP 733
Query: 754 PAKASEDWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAER 813
+ + W+C+RC NA +CCLC+LRGGAL++ +++W HV CAVA+ E RF N+ ER
Sbjct: 734 SHEICDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVRFTNVPER 793
Query: 814 SPVDVSKIPLPRFKLKCIFCKKRRKRTAGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDW 873
+ +DV +IPL R KLKCIFC+ R KR +G C+QCS+GRCP +FHV+CA AAGV+M+PDDW
Sbjct: 794 TQIDVGRIPLQRLKLKCIFCRHRVKRVSGACIQCSYGRCPASFHVTCAHAAGVLMEPDDW 853
Query: 874 PFVVFITCFRHKIPNLERAKGALQSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFD 933
P+VV ITCFRHK+ ++K + I+ GQ VI+KH+N R+Y C V+ +T++TFYEV FD
Sbjct: 854 PYVVNITCFRHKVNPNVKSKACEKVISVGQTVITKHRNTRYYSCRVMAVTSQTFYEVMFD 913
Query: 934 DGSFSDNLYPEDIVSQDCLQFGPPAEGEVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDG 993
DGSFS + +PEDIVS+DCL+ GPPAEGEVVQV+W DG++YGAK+ S+ MYQVEFEDG
Sbjct: 914 DGSFSRDTFPEDIVSRDCLKLGPPAEGEVVQVKWPDGKLYGAKYFGSNIAHMYQVEFEDG 973
Query: 994 SQLVVKRDDVYTLDEELPKRVKSRLSVASDMRFNEIFTEKEVKQ-EKKRQRVINSRYRED 1052
SQ+ +KR+D+YTLDEELPKRVK+R S ASDMRF + F ++ Q E+KRQRV++SR++ +
Sbjct: 974 SQIAMKREDIYTLDEELPKRVKARFSTASDMRFEDTFYGADIIQGERKRQRVLSSRFKNE 1033
Query: 1053 YIEPALYRAIME 1064
Y+ +YR ++
Sbjct: 1034 YVADPVYRTFLK 1045
>gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens]
Length = 1047
Score = 1140 bits (2949), Expect = 0.0
Identities = 576/1044 (55%), Positives = 725/1044 (69%), Gaps = 76/1044 (7%)
Query: 1 MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYD 60
+A LNPS +IMTF P+MEEFR F++Y+AY+ES+GAHRAGLAKV+PPKEWKPR YD
Sbjct: 3 VAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYD 62
Query: 61 DIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERK 120
DID+L+IPAPIQQ+VTGQSGLFTQYNIQKKAMTV+EFR++ANS KYCTPRY ++E+LERK
Sbjct: 63 DIDNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLERK 122
Query: 121 YWKNLTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGM 180
YWKNLTF PIYGAD+NG++Y++ VDEWNI RL T+LD+VE+E GI+IEGVNTPYLYFGM
Sbjct: 123 YWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGM 182
Query: 181 WKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRH 240
WKT+FAWHTEDMDLYSINYLHFGEPKSWY++PPEHGKRLERLA+GFFP S+Q C+AFLRH
Sbjct: 183 WKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRH 242
Query: 241 KMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYG 300
KMTLISP +LKKYGIPFDK+TQEAGEFMITFPYGYHAGFNHGFNCAESTNFAT RWI+YG
Sbjct: 243 KMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYG 302
Query: 301 KQAVLCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLP----TPEAAEFLKE 356
K A LC+CRKDMVKISMD+FVRKFQP+RY+LWK GKD IDHT P TPE +L+
Sbjct: 303 KVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWLQR 362
Query: 357 SELPPRAGNEEECPEEDMEGVEDGEEGDLKTSLAKHRIGTKRHRVCLEIPQEVSQSELFP 416
+A +C + + EE E+ EV +E+ P
Sbjct: 363 RRKVRKASRSFQCARSTSKRPKADEEE--------------------EVSDEVDGAEV-P 401
Query: 417 KEDLSSEQYEMTECPAALAPVRPTHSSVR--------QVEDGLTFPDYSDSTEVKFEELK 468
D ++ +++E A +R T +S QVE L SD ++
Sbjct: 402 NPDSVTDDLKVSEKSEAAVKLRNTEASSEEESSASRMQVEQNL-----SDHIKLSGNSCL 456
Query: 469 NVKLEEEDEEEEQAAAALDLSVNPASVGGRLVFSGSKKKSSSSLGSGSSRDSISSDSETS 528
+ + E+ + E+ A A SV S S+ S L SG + S SE S
Sbjct: 457 STSVTEDIKTEDDKAYAY-RSVPSIS---------SEADDSIPLSSGYEKPEKSDPSELS 506
Query: 529 ---EPLSCRAQGQT-GVLT------VHSYAKGDGRVTVGEPCTRKKGSAARSFSERELAE 578
P SC + ++ GVLT V S+ G + GE G SF +AE
Sbjct: 507 WPKSPESCSSVAESNGVLTEGEESDVESHGNG---LEPGEIPAVPSGE-RNSFKVPSIAE 562
Query: 579 VADEYMFSLEENKKSKGRRQPLSKLPRHHP--LVLQECVSDDETSEQLTPEEEAEETEAW 636
ENK SK R PLS+ P P LV Q+ SD+E E L+ EEE EETE+W
Sbjct: 563 ---------GENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEVLSIEEEVEETESW 613
Query: 637 AKPLSQLWQNRPPNFEAEKEFNETMAQQAPHCAVCMIFQTYHQVEFGGFNQNC---GNAS 693
AKPL LWQ + PNF AE+E+N T+A+ PHCA+C + YH+ + +
Sbjct: 614 AKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDSSNEENDARWETKLD 673
Query: 694 DLAPQKQRTKPLIPEMCFTSTGCSTDINLSTPYLEEDGTSILVSCKKCSVRVHASCYGVP 753
++ + +TKPLIPEMCF + + + + +LEEDGTS+L+SC KC VRVHASCYG+P
Sbjct: 674 EVVTSEGKTKPLIPEMCFIYSEENIEYSPPNAFLEEDGTSLLISCAKCCVRVHASCYGIP 733
Query: 754 PAKASEDWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAER 813
+ + W+C+RC NA +CCLC+LRGGAL++ +++W HV CAVA+ E RF N+ ER
Sbjct: 734 SHEICDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVRFTNVPER 793
Query: 814 SPVDVSKIPLPRFKLKCIFCKKRRKRTAGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDW 873
+ +DV +IPL R KLKCIFC+ R KR +G C+QCS+GRCP +FHV+CA AAGV+M+PDDW
Sbjct: 794 TQIDVGRIPLQRLKLKCIFCRHRVKRVSGACIQCSYGRCPASFHVTCAHAAGVLMEPDDW 853
Query: 874 PFVVFITCFRHKIPNLERAKGALQSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFD 933
P+VV ITCFRHK+ ++K + I+ GQ VI+KH+N R+Y C V+ +T++TFYEV FD
Sbjct: 854 PYVVNITCFRHKVNPNVKSKACEKVISVGQTVITKHRNTRYYSCRVMAVTSQTFYEVMFD 913
Query: 934 DGSFSDNLYPEDIVSQDCLQFGPPAEGEVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDG 993
DGSFS + +PEDIVS+DCL+ GPPAEGEVVQV+W DG++YGAK+ S+ MYQVEFEDG
Sbjct: 914 DGSFSRDTFPEDIVSRDCLKLGPPAEGEVVQVKWPDGKLYGAKYFGSNIAHMYQVEFEDG 973
Query: 994 SQLVVKRDDVYTLDEELPKRVKSR 1017
SQ+ +KR+D+YTLDEELPKRVK+R
Sbjct: 974 SQIAMKREDIYTLDEELPKRVKAR 997
>gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens]
Length = 813
Score = 867 bits (2239), Expect = 0.0
Identities = 454/855 (53%), Positives = 568/855 (66%), Gaps = 76/855 (8%)
Query: 1 MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYD 60
+A LNPS +IMTF P+MEEFR F++Y+AY+ES+GAHRAGLAKV+PPKEWKPR YD
Sbjct: 3 VAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYD 62
Query: 61 DIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERK 120
DID+L+IPAPIQQ+VTGQSGLFTQYNIQKKAMTV+EFR++ANS KYCTPRY ++E+LERK
Sbjct: 63 DIDNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLERK 122
Query: 121 YWKNLTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGM 180
YWKNLTF PIYGAD+NG++Y++ VDEWNI RL T+LD+VE+E GI+IEGVNTPYLYFGM
Sbjct: 123 YWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGM 182
Query: 181 WKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRH 240
WKT+FAWHTEDMDLYSINYLHFGEPKSWY++PPEHGKRLERLA+GFFP S+Q C+AFLRH
Sbjct: 183 WKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRH 242
Query: 241 KMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYG 300
KMTLISP +LKKYGIPFDK+TQEAGEFMITFPYGYHAGFNHGFNCAESTNFAT RWI+YG
Sbjct: 243 KMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYG 302
Query: 301 KQAVLCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLP----TPEAAEFLKE 356
K A LC+CRKDMVKISMD+FVRKFQP+RY+LWK GKD IDHT P TPE +L+
Sbjct: 303 KVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWLQR 362
Query: 357 SELPPRAGNEEECPEEDMEGVEDGEEGDLKTSLAKHRIGTKRHRVCLEIPQEVSQSELFP 416
+A +C + + EE E+ EV +E+ P
Sbjct: 363 RRKVRKASRSFQCARSTSKRPKADEEE--------------------EVSDEVDGAEV-P 401
Query: 417 KEDLSSEQYEMTECPAALAPVRPTHSSVR--------QVEDGLTFPDYSDSTEVKFEELK 468
D ++ +++E A +R T +S QVE L SD ++
Sbjct: 402 NPDSVTDDLKVSEKSEAAVKLRNTEASSEEESSASRMQVEQNL-----SDHIKLSGNSCL 456
Query: 469 NVKLEEEDEEEEQAAAALDLSVNPASVGGRLVFSGSKKKSSSSLGSGSSRDSISSDSETS 528
+ + E+ + E+ A A SV S S+ S L SG + S SE S
Sbjct: 457 STSVTEDIKTEDDKAYAY-RSVPSIS---------SEADDSIPLSSGYEKPEKSDPSELS 506
Query: 529 ---EPLSCRAQGQT-GVLT------VHSYAKGDGRVTVGEPCTRKKGSAARSFSERELAE 578
P SC + ++ GVLT V S+ G + GE G SF +AE
Sbjct: 507 WPKSPESCSSVAESNGVLTEGEESDVESHGNG---LEPGEIPAVPSGE-RNSFKVPSIAE 562
Query: 579 VADEYMFSLEENKKSKGRRQPLSKLPRHHP--LVLQECVSDDETSEQLTPEEEAEETEAW 636
ENK SK R PLS+ P P LV Q+ SD+E E L+ EEE EETE+W
Sbjct: 563 ---------GENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEVLSIEEEVEETESW 613
Query: 637 AKPLSQLWQNRPPNFEAEKEFNETMAQQAPHCAVCMIFQTYHQVEFGGFNQNC---GNAS 693
AKPL LWQ + PNF AE+E+N T+A+ PHCA+C + YH+ + +
Sbjct: 614 AKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDSSNEENDARWETKLD 673
Query: 694 DLAPQKQRTKPLIPEMCFTSTGCSTDINLSTPYLEEDGTSILVSCKKCSVRVHASCYGVP 753
++ + +TKPLIPEMCF + + + + +LEEDGTS+L+SC KC VRVHASCYG+P
Sbjct: 674 EVVTSEGKTKPLIPEMCFIYSEENIEYSPPNAFLEEDGTSLLISCAKCCVRVHASCYGIP 733
Query: 754 PAKASEDWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAER 813
+ + W+C+RC NA +CCLC+LRGGAL++ +++W HV CAVA+ E RF N+ ER
Sbjct: 734 SHEICDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVRFTNVPER 793
Query: 814 SPVDVSKIPLPRFKL 828
+ +DV +IPL R KL
Sbjct: 794 TQIDVGRIPLQRLKL 808
>gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens]
Length = 835
Score = 867 bits (2239), Expect = 0.0
Identities = 454/855 (53%), Positives = 568/855 (66%), Gaps = 76/855 (8%)
Query: 1 MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYD 60
+A LNPS +IMTF P+MEEFR F++Y+AY+ES+GAHRAGLAKV+PPKEWKPR YD
Sbjct: 25 VAEVESPLNPSCKIMTFRPSMEEFREFNKYLAYMESKGAHRAGLAKVIPPKEWKPRQCYD 84
Query: 61 DIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERK 120
DID+L+IPAPIQQ+VTGQSGLFTQYNIQKKAMTV+EFR++ANS KYCTPRY ++E+LERK
Sbjct: 85 DIDNLLIPAPIQQMVTGQSGLFTQYNIQKKAMTVKEFRQLANSGKYCTPRYLDYEDLERK 144
Query: 121 YWKNLTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGM 180
YWKNLTF PIYGAD+NG++Y++ VDEWNI RL T+LD+VE+E GI+IEGVNTPYLYFGM
Sbjct: 145 YWKNLTFVAPIYGADINGSIYDEGVDEWNIARLNTVLDVVEEECGISIEGVNTPYLYFGM 204
Query: 181 WKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRH 240
WKT+FAWHTEDMDLYSINYLHFGEPKSWY++PPEHGKRLERLA+GFFP S+Q C+AFLRH
Sbjct: 205 WKTTFAWHTEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAQGFFPSSSQGCDAFLRH 264
Query: 241 KMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYG 300
KMTLISP +LKKYGIPFDK+TQEAGEFMITFPYGYHAGFNHGFNCAESTNFAT RWI+YG
Sbjct: 265 KMTLISPSVLKKYGIPFDKITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATVRWIDYG 324
Query: 301 KQAVLCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLP----TPEAAEFLKE 356
K A LC+CRKDMVKISMD+FVRKFQP+RY+LWK GKD IDHT P TPE +L+
Sbjct: 325 KVAKLCTCRKDMVKISMDIFVRKFQPDRYQLWKQGKDIYTIDHTKPTPASTPEVKAWLQR 384
Query: 357 SELPPRAGNEEECPEEDMEGVEDGEEGDLKTSLAKHRIGTKRHRVCLEIPQEVSQSELFP 416
+A +C + + EE E+ EV +E+ P
Sbjct: 385 RRKVRKASRSFQCARSTSKRPKADEEE--------------------EVSDEVDGAEV-P 423
Query: 417 KEDLSSEQYEMTECPAALAPVRPTHSSVR--------QVEDGLTFPDYSDSTEVKFEELK 468
D ++ +++E A +R T +S QVE L SD ++
Sbjct: 424 NPDSVTDDLKVSEKSEAAVKLRNTEASSEEESSASRMQVEQNL-----SDHIKLSGNSCL 478
Query: 469 NVKLEEEDEEEEQAAAALDLSVNPASVGGRLVFSGSKKKSSSSLGSGSSRDSISSDSETS 528
+ + E+ + E+ A A SV S S+ S L SG + S SE S
Sbjct: 479 STSVTEDIKTEDDKAYAY-RSVPSIS---------SEADDSIPLSSGYEKPEKSDPSELS 528
Query: 529 ---EPLSCRAQGQT-GVLT------VHSYAKGDGRVTVGEPCTRKKGSAARSFSERELAE 578
P SC + ++ GVLT V S+ G + GE G SF +AE
Sbjct: 529 WPKSPESCSSVAESNGVLTEGEESDVESHGNG---LEPGEIPAVPSGE-RNSFKVPSIAE 584
Query: 579 VADEYMFSLEENKKSKGRRQPLSKLPRHHP--LVLQECVSDDETSEQLTPEEEAEETEAW 636
ENK SK R PLS+ P P LV Q+ SD+E E L+ EEE EETE+W
Sbjct: 585 ---------GENKTSKSWRHPLSRPPARSPMTLVKQQAPSDEELPEVLSIEEEVEETESW 635
Query: 637 AKPLSQLWQNRPPNFEAEKEFNETMAQQAPHCAVCMIFQTYHQVEFGGFNQNC---GNAS 693
AKPL LWQ + PNF AE+E+N T+A+ PHCA+C + YH+ + +
Sbjct: 636 AKPLIHLWQTKSPNFAAEQEYNATVARMKPHCAICTLLMPYHKPDSSNEENDARWETKLD 695
Query: 694 DLAPQKQRTKPLIPEMCFTSTGCSTDINLSTPYLEEDGTSILVSCKKCSVRVHASCYGVP 753
++ + +TKPLIPEMCF + + + + +LEEDGTS+L+SC KC VRVHASCYG+P
Sbjct: 696 EVVTSEGKTKPLIPEMCFIYSEENIEYSPPNAFLEEDGTSLLISCAKCCVRVHASCYGIP 755
Query: 754 PAKASEDWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAER 813
+ + W+C+RC NA +CCLC+LRGGAL++ +++W HV CAVA+ E RF N+ ER
Sbjct: 756 SHEICDGWLCARCKRNAWTAECCLCNLRGGALKQTKNNKWAHVMCAVAVPEVRFTNVPER 815
Query: 814 SPVDVSKIPLPRFKL 828
+ +DV +IPL R KL
Sbjct: 816 TQIDVGRIPLQRLKL 830
>gi|45504380 jumonji domain containing 2B [Homo sapiens]
Length = 1096
Score = 608 bits (1567), Expect = e-173
Identities = 274/339 (80%), Positives = 313/339 (92%)
Query: 9 NPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIP 68
NPS +IMTF PTMEEF++F++Y+AYIESQGAHRAGLAK++PPKEWKPR +YDDIDD+VIP
Sbjct: 10 NPSCKIMTFRPTMEEFKDFNKYVAYIESQGAHRAGLAKIIPPKEWKPRQTYDDIDDVVIP 69
Query: 69 APIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFN 128
APIQQ+VTGQSGLFTQYNIQKKAMTV E+R++ANS+KYCTPR+ +F++LERKYWKNLTF
Sbjct: 70 APIQQVVTGQSGLFTQYNIQKKAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFV 129
Query: 129 PPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWH 188
PIYGAD++G+LY+ V +WNIG LRTILD+VE+E G IEGVNTPYLYFGMWKT+FAWH
Sbjct: 130 SPIYGADISGSLYDDDVAQWNIGSLRTILDMVERECGTIIEGVNTPYLYFGMWKTTFAWH 189
Query: 189 TEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPL 248
TEDMDLYSINYLHFGEPKSWY++PPEHGKRLERLA GFFPGS+Q C+AFLRHKMTLISP+
Sbjct: 190 TEDMDLYSINYLHFGEPKSWYAIPPEHGKRLERLAIGFFPGSSQGCDAFLRHKMTLISPI 249
Query: 249 MLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSC 308
+LKKYGIPF ++TQEAGEFMITFPYGYHAGFNHGFNCAESTNFAT RWI+YGK A C+C
Sbjct: 250 ILKKYGIPFSRITQEAGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGKVATQCTC 309
Query: 309 RKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLPT 347
RKDMVKISMDVFVR QPERY+LWK GKD TV+DHT PT
Sbjct: 310 RKDMVKISMDVFVRILQPERYELWKQGKDLTVLDHTRPT 348
Score = 486 bits (1252), Expect = e-137
Identities = 237/488 (48%), Positives = 332/488 (68%), Gaps = 12/488 (2%)
Query: 585 FSLEENKKSKGRRQPLSKLPRHHPL-VLQECVSDDETSEQLTPEEEAEETEAWAKPLSQL 643
FS + + K RR PL + P PL V+++ S DE + + EE+ + +A LS
Sbjct: 600 FSKLKMEIKKSRRHPLGRPPTRSPLSVVKQEASSDEEASPFSGEEDVSDPDALRPLLSLQ 659
Query: 644 WQNRPPNFEAEKEFNETMAQQAPHCAVCMIF-------QTYHQVEFGGFNQNCGNASDLA 696
W+NR +F+AE++FN A+ P+CA+C +F QT + + C A+ +
Sbjct: 660 WKNRAASFQAERKFNAAAARTEPYCAICTLFYPYCQALQTEKEAPIASLGEGCP-ATLPS 718
Query: 697 PQKQRTKPLIPEMCFTSTGCSTDINLSTPYLEEDGTSILVSCKKCSVRVHASCYGVPPAK 756
+Q+T+PLIPEMCFTS G +T+ + Y+ +DGTS L++C KC ++VHASCYG+ P
Sbjct: 719 KSRQKTRPLIPEMCFTSGGENTEPLPANSYIGDDGTSPLIACGKCCLQVHASCYGIRPEL 778
Query: 757 ASEDWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAERSPV 816
+E W CSRC+A+A +CCLC+LRGGALQ D RW+HV CA+A+ EARF+N+ ER PV
Sbjct: 779 VNEGWTCSRCAAHAWTAECCLCNLRGGALQMTTDRRWIHVICAIAVPEARFLNVIERHPV 838
Query: 817 DVSKIPLPRFKLKCIFCKKRRKRTAGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDWPFV 876
D+S IP R+KLKC++C+KR K+ +G C+QCS+ C T+FHV+CA AAGV+M+PDDWP+V
Sbjct: 839 DISAIPEQRWKLKCVYCRKRMKKVSGACIQCSYEHCSTSFHVTCAHAAGVLMEPDDWPYV 898
Query: 877 VFITCFRHKIPNLERAKGALQSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGS 936
V ITC +HK A L++++ GQ VI+K++NG +Y+C V+ ++T YEVNFDDGS
Sbjct: 899 VSITCLKHKSGG--HAVQLLRAVSLGQVVITKNRNGLYYRCRVIGAASQTCYEVNFDDGS 956
Query: 937 FSDNLYPEDIVSQDCLQFGPPAEGEVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQL 996
+SDNLYPE I S+DC+Q GPP+EGE+V++RWTDG +Y AKF++S +YQVEFEDGSQL
Sbjct: 957 YSDNLYPESITSRDCVQLGPPSEGELVELRWTDGNLYKAKFISSVTSHIYQVEFEDGSQL 1016
Query: 997 VVKRDDVYTLDEELPKRVKSRLSVASDMRFNEIFTEKEVKQEKKRQRVINSRYREDYIEP 1056
VKR D++TL+EELPKRV+SRLS+++ F+ +E K KR RV ED
Sbjct: 1017 TVKRGDIFTLEEELPKRVRSRLSLSTGAPQEPAFSGEEAK-AAKRPRVGTPLATEDSGRS 1075
Query: 1057 ALYRAIME 1064
Y A +E
Sbjct: 1076 QDYVAFVE 1083
>gi|39653317 jumonji domain containing 2D [Homo sapiens]
Length = 523
Score = 518 bits (1333), Expect = e-146
Identities = 234/358 (65%), Positives = 291/358 (81%), Gaps = 3/358 (0%)
Query: 9 NPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIP 68
NP+ IM F+PT EEF +F +YIAY+ESQGAHRAGLAK++PPKEWK R +YD+I +++I
Sbjct: 13 NPNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKARETYDNISEILIA 72
Query: 69 APIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFN 128
P+QQ+ +G++G+FTQY+ +KKAMTV E+R +ANS KY TP + FE+LERKYWKN +N
Sbjct: 73 TPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFEDLERKYWKNRIYN 132
Query: 129 PPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWH 188
PIYGAD++G+L++++ +WN+G L TI DL+EKE G+ IEGVNTPYLYFGMWKT+FAWH
Sbjct: 133 SPIYGADISGSLFDENTKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYFGMWKTTFAWH 192
Query: 189 TEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPL 248
TEDMDLYSINYLH GEPK+WY VPPEHG+RLERLA+ FPGS++ C AFLRHK+ LISP
Sbjct: 193 TEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFLRHKVALISPT 252
Query: 249 MLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSC 308
+LK+ GIPF+++TQEAGEFM+TFPYGYHAGFNHGFNCAE+ NFAT RWI+YGK A CSC
Sbjct: 253 VLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSC 312
Query: 309 RKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLPTPEAAEFL---KESELPPRA 363
+ V SMD FVR QPERY LWK G+D V+DH P A++ L KE +LP RA
Sbjct: 313 GEARVTFSMDAFVRILQPERYDLWKRGQDRAVVDHMEPRVPASQELSTQKEVQLPRRA 370
>gi|169203160 PREDICTED: hypothetical protein [Homo sapiens]
Length = 638
Score = 502 bits (1292), Expect = e-142
Identities = 227/342 (66%), Positives = 279/342 (81%)
Query: 5 SETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDD 64
S N S IMTFYPTMEEF +F+ Y+AY+ESQGAHRAGLAKV+PPKEWK R YDDI+D
Sbjct: 6 SSPQNTSHTIMTFYPTMEEFADFNTYVAYMESQGAHRAGLAKVIPPKEWKARQMYDDIED 65
Query: 65 LVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKN 124
++I P+QQ+ +GQ G+FTQY+ +KKAM V ++R +ANS KY TP + F +LE++YWK+
Sbjct: 66 ILIATPLQQVTSGQGGVFTQYHKKKKAMRVGQYRHLANSKKYQTPPHQNFADLEQRYWKS 125
Query: 125 LTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTS 184
NPPIYGAD++G+L+E+ +WN+G L TILDL+E+E G+ IEGVNTPYLYFGMWKT+
Sbjct: 126 HPGNPPIYGADISGSLFEESTKQWNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTT 185
Query: 185 FAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTL 244
FAWHTEDMDLYSINYLHFGEPK+WY VPPEHG+RLE LA+ FPG+++ CE FLRHK+ L
Sbjct: 186 FAWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQRLECLARELFPGNSRGCEGFLRHKVAL 245
Query: 245 ISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAV 304
ISP +LKK GIPF+++TQEAGEFM+TFPYGYHAGFNHGFNCAE+ NFAT RWI+YGK A
Sbjct: 246 ISPTVLKKNGIPFNRMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKVAS 305
Query: 305 LCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLP 346
CSC + V SMD FVR QPE Y+LWK +D TV+D+ P
Sbjct: 306 QCSCGEARVTFSMDAFVRILQPESYELWKHRQDLTVVDYMEP 347
>gi|169203656 PREDICTED: hypothetical protein [Homo sapiens]
Length = 638
Score = 502 bits (1292), Expect = e-142
Identities = 227/342 (66%), Positives = 279/342 (81%)
Query: 5 SETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDD 64
S N S IMTFYPTMEEF +F+ Y+AY+ESQGAHRAGLAKV+PPKEWK R YDDI+D
Sbjct: 6 SSPQNTSHTIMTFYPTMEEFADFNTYVAYMESQGAHRAGLAKVIPPKEWKARQMYDDIED 65
Query: 65 LVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKN 124
++I P+QQ+ +GQ G+FTQY+ +KKAM V ++R +ANS KY TP + F +LE++YWK+
Sbjct: 66 ILIATPLQQVTSGQGGVFTQYHKKKKAMRVGQYRHLANSKKYQTPPHQNFADLEQRYWKS 125
Query: 125 LTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTS 184
NPPIYGAD++G+L+E+ +WN+G L TILDL+E+E G+ IEGVNTPYLYFGMWKT+
Sbjct: 126 HPGNPPIYGADISGSLFEESTKQWNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTT 185
Query: 185 FAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTL 244
FAWHTEDMDLYSINYLHFGEPK+WY VPPEHG+RLE LA+ FPG+++ CE FLRHK+ L
Sbjct: 186 FAWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQRLECLARELFPGNSRGCEGFLRHKVAL 245
Query: 245 ISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAV 304
ISP +LKK GIPF+++TQEAGEFM+TFPYGYHAGFNHGFNCAE+ NFAT RWI+YGK A
Sbjct: 246 ISPTVLKKNGIPFNRMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKVAS 305
Query: 305 LCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLP 346
CSC + V SMD FVR QPE Y+LWK +D TV+D+ P
Sbjct: 306 QCSCGEARVTFSMDAFVRILQPESYELWKHRQDLTVVDYMEP 347
>gi|169202387 PREDICTED: hypothetical protein [Homo sapiens]
Length = 638
Score = 502 bits (1292), Expect = e-142
Identities = 227/342 (66%), Positives = 279/342 (81%)
Query: 5 SETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDD 64
S N S IMTFYPTMEEF +F+ Y+AY+ESQGAHRAGLAKV+PPKEWK R YDDI+D
Sbjct: 6 SSPQNTSHTIMTFYPTMEEFADFNTYVAYMESQGAHRAGLAKVIPPKEWKARQMYDDIED 65
Query: 65 LVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKN 124
++I P+QQ+ +GQ G+FTQY+ +KKAM V ++R +ANS KY TP + F +LE++YWK+
Sbjct: 66 ILIATPLQQVTSGQGGVFTQYHKKKKAMRVGQYRHLANSKKYQTPPHQNFADLEQRYWKS 125
Query: 125 LTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTS 184
NPPIYGAD++G+L+E+ +WN+G L TILDL+E+E G+ IEGVNTPYLYFGMWKT+
Sbjct: 126 HPGNPPIYGADISGSLFEESTKQWNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTT 185
Query: 185 FAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTL 244
FAWHTEDMDLYSINYLHFGEPK+WY VPPEHG+RLE LA+ FPG+++ CE FLRHK+ L
Sbjct: 186 FAWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQRLECLARELFPGNSRGCEGFLRHKVAL 245
Query: 245 ISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAV 304
ISP +LKK GIPF+++TQEAGEFM+TFPYGYHAGFNHGFNCAE+ NFAT RWI+YGK A
Sbjct: 246 ISPTVLKKNGIPFNRMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKVAS 305
Query: 305 LCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLP 346
CSC + V SMD FVR QPE Y+LWK +D TV+D+ P
Sbjct: 306 QCSCGEARVTFSMDAFVRILQPESYELWKHRQDLTVVDYMEP 347
>gi|239744460 PREDICTED: hypothetical protein [Homo sapiens]
Length = 506
Score = 498 bits (1282), Expect = e-140
Identities = 224/342 (65%), Positives = 278/342 (81%)
Query: 5 SETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDD 64
S N S IMTFYPTMEEF +F+ Y+AY+ESQGAH+AGLAKV+PPKEWK R YDDI+D
Sbjct: 6 SSPQNTSHTIMTFYPTMEEFADFNTYVAYMESQGAHQAGLAKVIPPKEWKARQMYDDIED 65
Query: 65 LVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKN 124
++I P+QQ+ +GQ G+FTQY+ +KKAM V ++R++ANS KY TP + F +LE++YWK+
Sbjct: 66 ILIATPLQQVTSGQGGVFTQYHKKKKAMRVGQYRRLANSKKYQTPPHQNFADLEQRYWKS 125
Query: 125 LTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTS 184
NPPIYGAD++G+L+E+ +WN+G L TILDL+E+E G+ IEGVNTPYLYFGMWKT+
Sbjct: 126 HPGNPPIYGADISGSLFEESTKQWNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTT 185
Query: 185 FAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTL 244
FAWHTEDMDLYSINYLHFGEPK+WY VPPEHG+ LERLA+ FP ++ CEAFLRHK+ L
Sbjct: 186 FAWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQHLERLARELFPDISRGCEAFLRHKVAL 245
Query: 245 ISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAV 304
ISP +LK+ GIPF+ +TQEAGEFM+TFPYGYHAGFNHGFNCAE+ NFAT RWI+YGK A
Sbjct: 246 ISPTVLKENGIPFNCMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMAS 305
Query: 305 LCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLP 346
CSC + V SMD FVR QPE Y+LWK +D +++HT P
Sbjct: 306 QCSCGESTVTFSMDPFVRIVQPESYELWKHRQDLAIVEHTEP 347
>gi|239755681 PREDICTED: hypothetical protein [Homo sapiens]
Length = 506
Score = 498 bits (1281), Expect = e-140
Identities = 224/342 (65%), Positives = 278/342 (81%)
Query: 5 SETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDD 64
S N S IMTFYPTMEEF +F+ Y+AY+ESQGAH+AGLAKV+PPKEWK R YDDI+D
Sbjct: 6 SSPQNTSHTIMTFYPTMEEFADFNTYVAYMESQGAHQAGLAKVIPPKEWKARQMYDDIED 65
Query: 65 LVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKN 124
++I P+QQ+ +GQ G+FTQY+ +KKAM V ++R++ANS KY TP + F +LE++YWK+
Sbjct: 66 ILIATPLQQVTSGQGGVFTQYHKKKKAMRVGQYRRLANSKKYQTPPHRNFADLEQRYWKS 125
Query: 125 LTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTS 184
NPPIYGAD++G+L+E+ +WN+G L TILDL+E+E G+ IEGVNTPYLYFGMWKT+
Sbjct: 126 HPGNPPIYGADISGSLFEESTKQWNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTT 185
Query: 185 FAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTL 244
FAWHTEDMDLYSINYLHFGEPK+WY VPPEHG+ LERLA+ FP ++ CEAFLRHK+ L
Sbjct: 186 FAWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQHLERLARELFPDISRGCEAFLRHKVAL 245
Query: 245 ISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAV 304
ISP +LK+ GIPF+ +TQEAGEFM+TFPYGYHAGFNHGFNCAE+ NFAT RWI+YGK A
Sbjct: 246 ISPTVLKENGIPFNCMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMAS 305
Query: 305 LCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLP 346
CSC + V SMD FVR QPE Y+LWK +D +++HT P
Sbjct: 306 QCSCGESTVTFSMDPFVRIVQPESYELWKHRQDLAIVEHTEP 347
>gi|239750150 PREDICTED: hypothetical protein [Homo sapiens]
Length = 506
Score = 498 bits (1281), Expect = e-140
Identities = 224/342 (65%), Positives = 278/342 (81%)
Query: 5 SETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDD 64
S N S IMTFYPTMEEF +F+ Y+AY+ESQGAH+AGLAKV+PPKEWK R YDDI+D
Sbjct: 6 SSPQNTSHTIMTFYPTMEEFADFNTYVAYMESQGAHQAGLAKVIPPKEWKARQMYDDIED 65
Query: 65 LVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKN 124
++I P+QQ+ +GQ G+FTQY+ +KKAM V ++R++ANS KY TP + F +LE++YWK+
Sbjct: 66 ILIATPLQQVTSGQGGVFTQYHKKKKAMRVGQYRRLANSKKYQTPPHRNFADLEQRYWKS 125
Query: 125 LTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTS 184
NPPIYGAD++G+L+E+ +WN+G L TILDL+E+E G+ IEGVNTPYLYFGMWKT+
Sbjct: 126 HPGNPPIYGADISGSLFEESTKQWNLGHLGTILDLLEQECGVVIEGVNTPYLYFGMWKTT 185
Query: 185 FAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTL 244
FAWHTEDMDLYSINYLHFGEPK+WY VPPEHG+ LERLA+ FP ++ CEAFLRHK+ L
Sbjct: 186 FAWHTEDMDLYSINYLHFGEPKTWYVVPPEHGQHLERLARELFPDISRGCEAFLRHKVAL 245
Query: 245 ISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAV 304
ISP +LK+ GIPF+ +TQEAGEFM+TFPYGYHAGFNHGFNCAE+ NFAT RWI+YGK A
Sbjct: 246 ISPTVLKENGIPFNCMTQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMAS 305
Query: 305 LCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLP 346
CSC + V SMD FVR QPE Y+LWK +D +++HT P
Sbjct: 306 QCSCGESTVTFSMDPFVRIVQPESYELWKHRQDLAIVEHTEP 347
>gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo
sapiens]
Length = 1690
Score = 144 bits (363), Expect = 4e-34
Identities = 65/157 (41%), Positives = 95/157 (60%)
Query: 148 WNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKS 207
WN+ + + V + I G+ P+LY GM +SF WH ED YSINYLH+GEPK+
Sbjct: 443 WNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKT 502
Query: 208 WYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEF 267
WY VP ++LE + + P +S L +T+++P +L ++G+P + Q AGEF
Sbjct: 503 WYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEF 562
Query: 268 MITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAV 304
++TFP YH+GFN G+N AE+ NF T W+ G+Q V
Sbjct: 563 VVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCV 599
Score = 33.5 bits (75), Expect = 1.1
Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 1/46 (2%)
Query: 10 PSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKP 55
P F P+ EEF + +I I A + G+ K+ PPK+W+P
Sbjct: 15 PPPECPVFEPSWEEFTDPLSFIGRIRPL-AEKTGICKIRPPKDWQP 59
>gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo
sapiens]
Length = 1641
Score = 144 bits (363), Expect = 4e-34
Identities = 65/157 (41%), Positives = 95/157 (60%)
Query: 148 WNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKS 207
WN+ + + V + I G+ P+LY GM +SF WH ED YSINYLH+GEPK+
Sbjct: 443 WNLNNMPVLEQSVLAHINVDISGMKVPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKT 502
Query: 208 WYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEF 267
WY VP ++LE + + P +S L +T+++P +L ++G+P + Q AGEF
Sbjct: 503 WYGVPSHAAEQLEEVMRELAPELFESQPDLLHQLVTIMNPNVLMEHGVPVYRTNQCAGEF 562
Query: 268 MITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAV 304
++TFP YH+GFN G+N AE+ NF T W+ G+Q V
Sbjct: 563 VVTFPRAYHSGFNQGYNFAEAVNFCTADWLPIGRQCV 599
Score = 33.5 bits (75), Expect = 1.1
Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 1/46 (2%)
Query: 10 PSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKP 55
P F P+ EEF + +I I A + G+ K+ PPK+W+P
Sbjct: 15 PPPECPVFEPSWEEFTDPLSFIGRIRPL-AEKTGICKIRPPKDWQP 59
>gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens]
Length = 1544
Score = 137 bits (346), Expect = 4e-32
Identities = 85/238 (35%), Positives = 125/238 (52%), Gaps = 26/238 (10%)
Query: 93 TVREFRKIAN---SDKYCTPRYSEFEEL-ERKYWKNL-TFNPPI---YGADVNGTLY--- 141
T+R F ++A+ SD + P + EL E+++W+ + T + YGAD+ +
Sbjct: 378 TLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSG 437
Query: 142 --------------EKHVDE-WNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFA 186
E+++D WN+ + + V I G+ P+LY GM +SF
Sbjct: 438 FPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFC 497
Query: 187 WHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLIS 246
WH ED YSINYLH+GEPK+WY VP ++LE + K P S L +T+++
Sbjct: 498 WHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMN 557
Query: 247 PLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAV 304
P L + +P + Q AGEF+ITFP YH+GFN GFN AE+ NF T W+ G+Q V
Sbjct: 558 PNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGRQCV 615
Score = 33.1 bits (74), Expect = 1.4
Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 2/65 (3%)
Query: 10 PSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIPA 69
P F P+ EEF + +I I A + G+ KV PP +W+P + D+D L
Sbjct: 28 PPPECPVFEPSWEEFADPFAFIHKIRPI-AEQTGICKVRPPPDWQPPFAC-DVDKLHFTP 85
Query: 70 PIQQL 74
IQ+L
Sbjct: 86 RIQRL 90
>gi|169218173 PREDICTED: similar to Jumonji, AT rich interactive
domain 1B (RBP2-like), partial [Homo sapiens]
Length = 977
Score = 137 bits (346), Expect = 4e-32
Identities = 85/238 (35%), Positives = 125/238 (52%), Gaps = 26/238 (10%)
Query: 93 TVREFRKIAN---SDKYCTPRYSEFEEL-ERKYWKNL-TFNPPI---YGADVNGTLY--- 141
T+R F ++A+ SD + P + EL E+++W+ + T + YGAD+ +
Sbjct: 378 TLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSG 437
Query: 142 --------------EKHVDE-WNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFA 186
E+++D WN+ + + V I G+ P+LY GM +SF
Sbjct: 438 FPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFC 497
Query: 187 WHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLIS 246
WH ED YSINYLH+GEPK+WY VP ++LE + K P S L +T+++
Sbjct: 498 WHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMN 557
Query: 247 PLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAV 304
P L + +P + Q AGEF+ITFP YH+GFN GFN AE+ NF T W+ G+Q V
Sbjct: 558 PNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGRQCV 615
Score = 33.1 bits (74), Expect = 1.4
Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 2/65 (3%)
Query: 10 PSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIPA 69
P F P+ EEF + +I I A + G+ KV PP +W+P + D+D L
Sbjct: 28 PPPECPVFEPSWEEFADPFAFIHKIRPI-AEQTGICKVRPPPDWQPPFAC-DVDKLHFTP 85
Query: 70 PIQQL 74
IQ+L
Sbjct: 86 RIQRL 90
>gi|226442963 jumonji, AT rich interactive domain 1C isoform 2 [Homo
sapiens]
Length = 1379
Score = 137 bits (345), Expect = 5e-32
Identities = 66/157 (42%), Positives = 90/157 (57%)
Query: 148 WNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKS 207
WN+ + + V I G+ P+LY GM ++F WH ED YSINYLH+GEPK+
Sbjct: 407 WNLNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKT 466
Query: 208 WYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEF 267
WY VP + LE + K P S L +TL++P L +G+P + Q AGEF
Sbjct: 467 WYGVPSLAAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEF 526
Query: 268 MITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAV 304
+ITFP YH+GFN G+N AE+ NF T W+ G+Q +
Sbjct: 527 VITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCI 563
>gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [Homo
sapiens]
Length = 1560
Score = 137 bits (345), Expect = 5e-32
Identities = 66/157 (42%), Positives = 90/157 (57%)
Query: 148 WNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKS 207
WN+ + + V I G+ P+LY GM ++F WH ED YSINYLH+GEPK+
Sbjct: 474 WNLNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKT 533
Query: 208 WYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEF 267
WY VP + LE + K P S L +TL++P L +G+P + Q AGEF
Sbjct: 534 WYGVPSLAAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEF 593
Query: 268 MITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAV 304
+ITFP YH+GFN G+N AE+ NF T W+ G+Q +
Sbjct: 594 VITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCI 630
Score = 36.2 bits (82), Expect = 0.17
Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 2/74 (2%)
Query: 1 MASESETLNPSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYD 60
M S+ P F P+ EFR+ YIA I A ++G+ K+ PP +W+P +
Sbjct: 1 MEPGSDDFLPPPECPVFEPSWAEFRDPLGYIAKIRPI-AEKSGICKIRPPADWQPPFAV- 58
Query: 61 DIDDLVIPAPIQQL 74
++D+ IQ+L
Sbjct: 59 EVDNFRFTPRIQRL 72
>gi|226442991 jumonji, AT rich interactive domain 1D isoform 1 [Homo
sapiens]
Length = 1570
Score = 137 bits (345), Expect = 5e-32
Identities = 68/165 (41%), Positives = 92/165 (55%)
Query: 140 LYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINY 199
L E WN+ + + V I G+ P+LY GM ++F WH ED YSINY
Sbjct: 487 LQEYATSGWNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINY 546
Query: 200 LHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDK 259
LH+GEPK+WY VP + LE + K P S L +TL++P L +G+P +
Sbjct: 547 LHWGEPKTWYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVR 606
Query: 260 VTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAV 304
Q AGEF+ITFP YH+GFN G+N AE+ NF T W+ G+Q +
Sbjct: 607 TNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCI 651
Score = 33.1 bits (74), Expect = 1.4
Identities = 19/65 (29%), Positives = 34/65 (52%), Gaps = 2/65 (3%)
Query: 10 PSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIPA 69
P F P+ EF++ YIA I A ++G+ K+ PP +W+P + ++D+
Sbjct: 10 PPPECPVFEPSWAEFQDPLGYIAKIRPI-AEKSGICKIRPPADWQPPFAV-EVDNFRFTP 67
Query: 70 PIQQL 74
+Q+L
Sbjct: 68 RVQRL 72
>gi|226443002 jumonji, AT rich interactive domain 1D isoform 3 [Homo
sapiens]
Length = 1482
Score = 136 bits (343), Expect = 9e-32
Identities = 66/157 (42%), Positives = 90/157 (57%)
Query: 148 WNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKS 207
WN+ + + V I G+ P+LY GM ++F WH ED YSINYLH+GEPK+
Sbjct: 407 WNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKT 466
Query: 208 WYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEF 267
WY VP + LE + K P S L +TL++P L +G+P + Q AGEF
Sbjct: 467 WYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEF 526
Query: 268 MITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAV 304
+ITFP YH+GFN G+N AE+ NF T W+ G+Q +
Sbjct: 527 VITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCI 563
Score = 33.1 bits (74), Expect = 1.4
Identities = 19/65 (29%), Positives = 34/65 (52%), Gaps = 2/65 (3%)
Query: 10 PSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIPA 69
P F P+ EF++ YIA I A ++G+ K+ PP +W+P + ++D+
Sbjct: 10 PPPECPVFEPSWAEFQDPLGYIAKIRPI-AEKSGICKIRPPADWQPPFAV-EVDNFRFTP 67
Query: 70 PIQQL 74
+Q+L
Sbjct: 68 RVQRL 72
>gi|33356560 jumonji, AT rich interactive domain 1D isoform 2 [Homo
sapiens]
Length = 1539
Score = 136 bits (343), Expect = 9e-32
Identities = 66/157 (42%), Positives = 90/157 (57%)
Query: 148 WNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKS 207
WN+ + + V I G+ P+LY GM ++F WH ED YSINYLH+GEPK+
Sbjct: 464 WNLNVMPVLDQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHWSYSINYLHWGEPKT 523
Query: 208 WYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEF 267
WY VP + LE + K P S L +TL++P L +G+P + Q AGEF
Sbjct: 524 WYGVPSLAAEHLEEVMKMLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVVRTNQCAGEF 583
Query: 268 MITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAV 304
+ITFP YH+GFN G+N AE+ NF T W+ G+Q +
Sbjct: 584 VITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCI 620
Score = 33.1 bits (74), Expect = 1.4
Identities = 19/65 (29%), Positives = 34/65 (52%), Gaps = 2/65 (3%)
Query: 10 PSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIPA 69
P F P+ EF++ YIA I A ++G+ K+ PP +W+P + ++D+
Sbjct: 10 PPPECPVFEPSWAEFQDPLGYIAKIRPI-AEKSGICKIRPPADWQPPFAV-EVDNFRFTP 67
Query: 70 PIQQL 74
+Q+L
Sbjct: 68 RVQRL 72
>gi|11321642 bromodomain containing protein 1 [Homo sapiens]
Length = 1058
Score = 122 bits (305), Expect = 2e-27
Identities = 60/144 (41%), Positives = 83/144 (57%), Gaps = 6/144 (4%)
Query: 728 EEDGTSILVSCKKCSVRVHASCYGVPPAKASEDWMCSRC-SANALEEDCCLCSLRGGALQ 786
E +++++ C C++ VH CYGVP + W+C C + A DC LC +GGA +
Sbjct: 224 ECQNSNVILFCDMCNLAVHQECYGVPYIPEGQ-WLCRHCLQSRARPADCVLCPNKGGAFK 282
Query: 787 RANDDRWVHVSCAVAILEARFVNIAERSPVD-VSKIPLPRFKLKCIFCKKRRKRTAGCCV 845
+ +DDRW HV CA+ I E F N P+D V IP R+KL C CK ++ G C+
Sbjct: 283 KTDDDRWGHVVCALWIPEVGFANTVFIEPIDGVRNIPPARWKLTCYLCK---QKGVGACI 339
Query: 846 QCSHGRCPTAFHVSCAQAAGVMMQ 869
QC C TAFHV+CAQ AG+ M+
Sbjct: 340 QCHKANCYTAFHVTCAQKAGLYMK 363
>gi|51173722 bromodomain and PHD finger-containing protein 1 isoform
2 [Homo sapiens]
Length = 1214
Score = 121 bits (303), Expect = 4e-27
Identities = 59/144 (40%), Positives = 84/144 (58%), Gaps = 6/144 (4%)
Query: 728 EEDGTSILVSCKKCSVRVHASCYGVPPAKASEDWMCSRC-SANALEEDCCLCSLRGGALQ 786
E +++++ C C++ VH CYGVP + W+C RC + + DC LC +GGA +
Sbjct: 283 ECQNSNVILFCDMCNLAVHQECYGVPYIPEGQ-WLCRRCLQSPSRAVDCALCPNKGGAFK 341
Query: 787 RANDDRWVHVSCAVAILEARFVNIAERSPVD-VSKIPLPRFKLKCIFCKKRRKRTAGCCV 845
+ +D RW HV CA+ I E F N P+D + IP R+KL C CK +R +G C+
Sbjct: 342 QTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICK---QRGSGACI 398
Query: 846 QCSHGRCPTAFHVSCAQAAGVMMQ 869
QC C TAFHV+CAQ AG+ M+
Sbjct: 399 QCHKANCYTAFHVTCAQQAGLYMK 422
>gi|51173720 bromodomain and PHD finger-containing protein 1 isoform
1 [Homo sapiens]
Length = 1220
Score = 121 bits (303), Expect = 4e-27
Identities = 59/144 (40%), Positives = 84/144 (58%), Gaps = 6/144 (4%)
Query: 728 EEDGTSILVSCKKCSVRVHASCYGVPPAKASEDWMCSRC-SANALEEDCCLCSLRGGALQ 786
E +++++ C C++ VH CYGVP + W+C RC + + DC LC +GGA +
Sbjct: 283 ECQNSNVILFCDMCNLAVHQECYGVPYIPEGQ-WLCRRCLQSPSRAVDCALCPNKGGAFK 341
Query: 787 RANDDRWVHVSCAVAILEARFVNIAERSPVD-VSKIPLPRFKLKCIFCKKRRKRTAGCCV 845
+ +D RW HV CA+ I E F N P+D + IP R+KL C CK +R +G C+
Sbjct: 342 QTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICK---QRGSGACI 398
Query: 846 QCSHGRCPTAFHVSCAQAAGVMMQ 869
QC C TAFHV+CAQ AG+ M+
Sbjct: 399 QCHKANCYTAFHVTCAQQAGLYMK 422
>gi|148727368 bromodomain and PHD finger containing, 3 [Homo
sapiens]
Length = 1205
Score = 108 bits (269), Expect = 3e-23
Identities = 53/140 (37%), Positives = 79/140 (56%), Gaps = 6/140 (4%)
Query: 732 TSILVSCKKCSVRVHASCYGVPPAKASEDWMCSRC-SANALEEDCCLCSLRGGALQRAND 790
+++++ C C++ VH CYGVP + W+C C + + DC LC +GGA ++ +D
Sbjct: 226 SNVILFCDICNLAVHQECYGVPYIPEGQ-WLCRCCLQSPSRPVDCILCPNKGGAFKQTSD 284
Query: 791 DRWVHVSCAVAILEARFVNIAERSPVD-VSKIPLPRFKLKCIFCKKRRKRTAGCCVQCSH 849
W HV CA+ I E F N P++ + IP R+KL C CK ++ G +QC
Sbjct: 285 GHWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKLTCYICK---QKGLGAAIQCHK 341
Query: 850 GRCPTAFHVSCAQAAGVMMQ 869
C TAFHV+CAQ AG+ M+
Sbjct: 342 VNCYTAFHVTCAQRAGLFMK 361
>gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 6 [Homo sapiens]
Length = 1093
Score = 101 bits (251), Expect = 4e-21
Identities = 48/136 (35%), Positives = 72/136 (52%), Gaps = 6/136 (4%)
Query: 741 CSVRVHASCYGVPPAKASEDWMCSRCSAN--ALEEDCCLCSLRGGALQRANDDRWVHVSC 798
CSV VH +CYG+ W C +C + A C LC + GAL+R ++ W HV C
Sbjct: 30 CSVAVHQACYGIVQVPTGP-WFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVC 88
Query: 799 AVAILEARFVNIAERSPVDVSKIPLPRFKLKCIFCK---KRRKRTAGCCVQCSHGRCPTA 855
A+ I E +F N+ P+ + +P RF C C+ + K +G C+ C+ C A
Sbjct: 89 ALYIPEVQFANVLTMEPIVLQYVPHDRFNKTCYICEEQGRESKAASGACMTCNRHGCRQA 148
Query: 856 FHVSCAQAAGVMMQPD 871
FHV+CAQ AG++ + +
Sbjct: 149 FHVTCAQMAGLLCEEE 164
>gi|40556370 PHD finger protein 15 [Homo sapiens]
Length = 790
Score = 100 bits (249), Expect = 7e-21
Identities = 58/143 (40%), Positives = 77/143 (53%), Gaps = 9/143 (6%)
Query: 729 EDGTSILVSCKKCSVRVHASCYGVPPAKASEDWMCSRCSANALEEDCCLCSLRGGALQRA 788
EDG +V C KC+V VH +CYG+ W+C C A ++ C LC RGGAL+
Sbjct: 211 EDGNE-MVFCDKCNVCVHQACYGILKVPTGS-WLCRTC-ALGVQPKCLLCPKRGGALKPT 267
Query: 789 NDD-RWVHVSCAVAILEARFVNIAERSPVD-VSKIPLPRFKLKCIFCKKRRKRTAGCCVQ 846
+WVHVSCA+ I E + P+ +S IP R+ L C CK+ G C+Q
Sbjct: 268 RSGTKWVHVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLCKE----CTGTCIQ 323
Query: 847 CSHGRCPTAFHVSCAQAAGVMMQ 869
CS C TAFHV+CA G+ M+
Sbjct: 324 CSMPSCVTAFHVTCAFDHGLEMR 346
>gi|57546899 myeloid/lymphoid or mixed-lineage leukemia translocated
to, 10 isoform b [Homo sapiens]
Length = 1011
Score = 99.8 bits (247), Expect = 1e-20
Identities = 47/136 (34%), Positives = 71/136 (52%), Gaps = 6/136 (4%)
Query: 741 CSVRVHASCYGVPPAKASEDWMCSRCSAN--ALEEDCCLCSLRGGALQRANDDRWVHVSC 798
CSV VH +CYG+ W C +C + A C LC + GAL+R ++ W HV C
Sbjct: 47 CSVAVHQACYGIVQVPTGP-WFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVC 105
Query: 799 AVAILEARFVNIAERSPVDVSKIPLPRFKLKCIFCK---KRRKRTAGCCVQCSHGRCPTA 855
A+ I E +F N++ P+ + +P R+ C C + K G C+ C+ C A
Sbjct: 106 ALYIPEVQFANVSTMEPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQA 165
Query: 856 FHVSCAQAAGVMMQPD 871
FHV+CAQ AG++ + +
Sbjct: 166 FHVTCAQFAGLLCEEE 181
>gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocated
to, 10 isoform a [Homo sapiens]
Length = 1027
Score = 99.8 bits (247), Expect = 1e-20
Identities = 47/136 (34%), Positives = 71/136 (52%), Gaps = 6/136 (4%)
Query: 741 CSVRVHASCYGVPPAKASEDWMCSRCSAN--ALEEDCCLCSLRGGALQRANDDRWVHVSC 798
CSV VH +CYG+ W C +C + A C LC + GAL+R ++ W HV C
Sbjct: 47 CSVAVHQACYGIVQVPTGP-WFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVC 105
Query: 799 AVAILEARFVNIAERSPVDVSKIPLPRFKLKCIFCK---KRRKRTAGCCVQCSHGRCPTA 855
A+ I E +F N++ P+ + +P R+ C C + K G C+ C+ C A
Sbjct: 106 ALYIPEVQFANVSTMEPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQA 165
Query: 856 FHVSCAQAAGVMMQPD 871
FHV+CAQ AG++ + +
Sbjct: 166 FHVTCAQFAGLLCEEE 181
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,556,377
Number of Sequences: 37866
Number of extensions: 2184098
Number of successful extensions: 9710
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 137
Number of HSP's that attempted gapping in prelim test: 9028
Number of HSP's gapped (non-prelim): 641
length of query: 1064
length of database: 18,247,518
effective HSP length: 113
effective length of query: 951
effective length of database: 13,968,660
effective search space: 13284195660
effective search space used: 13284195660
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.