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Search of human proteins with 95147555
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|95147555 microtubule-associated protein 1A [Homo sapiens]
(2803 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 5663 0.0
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 681 0.0
gi|50428935 BPY2 interacting protein 1 [Homo sapiens] 293 2e-78
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 144 1e-33
gi|110349719 titin isoform N2-A [Homo sapiens] 140 2e-32
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 138 9e-32
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 136 3e-31
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 133 2e-30
gi|163965366 nascent polypeptide-associated complex alpha subuni... 130 1e-29
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 130 2e-29
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 126 3e-28
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 126 3e-28
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 120 2e-26
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 120 2e-26
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 117 1e-25
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 108 7e-23
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 105 6e-22
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 103 2e-21
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 103 2e-21
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 103 2e-21
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 103 2e-21
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 94 1e-18
gi|188536004 zinc finger protein 469 [Homo sapiens] 94 1e-18
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 94 2e-18
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 92 5e-18
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 92 5e-18
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 92 5e-18
gi|221219020 NYD-SP11 protein [Homo sapiens] 92 9e-18
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 92 9e-18
gi|150170670 piccolo isoform 2 [Homo sapiens] 90 4e-17
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 5663 bits (14691), Expect = 0.0
Identities = 2803/2803 (100%), Positives = 2803/2803 (100%)
Query: 1 MDGVAEFSEYVSETVDVPSPFDLLEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNI 60
MDGVAEFSEYVSETVDVPSPFDLLEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNI
Sbjct: 1 MDGVAEFSEYVSETVDVPSPFDLLEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNI 60
Query: 61 LVDGGSDRKSCFWKLVRHLDRIDSVLLTHIGADNLPGINGLLQRKVAELEEEQSQGSSSY 120
LVDGGSDRKSCFWKLVRHLDRIDSVLLTHIGADNLPGINGLLQRKVAELEEEQSQGSSSY
Sbjct: 61 LVDGGSDRKSCFWKLVRHLDRIDSVLLTHIGADNLPGINGLLQRKVAELEEEQSQGSSSY 120
Query: 121 SDWVKNLISPELGVVFFNVPEKLRLPDASRKAKRSIEEACLTLQHLNRLGIQAEPLYRVV 180
SDWVKNLISPELGVVFFNVPEKLRLPDASRKAKRSIEEACLTLQHLNRLGIQAEPLYRVV
Sbjct: 121 SDWVKNLISPELGVVFFNVPEKLRLPDASRKAKRSIEEACLTLQHLNRLGIQAEPLYRVV 180
Query: 181 SNTIEPLTLFHKMGVGRLDMYVLNPVKDSKEMQFLMQKWAGNSKAKTGIVLPNGKEAEIS 240
SNTIEPLTLFHKMGVGRLDMYVLNPVKDSKEMQFLMQKWAGNSKAKTGIVLPNGKEAEIS
Sbjct: 181 SNTIEPLTLFHKMGVGRLDMYVLNPVKDSKEMQFLMQKWAGNSKAKTGIVLPNGKEAEIS 240
Query: 241 VPYLTSITALVVWLPANPTEKIVRVLFPGNAPQNKILEGLEKLRHLDFLRYPVATQKDLA 300
VPYLTSITALVVWLPANPTEKIVRVLFPGNAPQNKILEGLEKLRHLDFLRYPVATQKDLA
Sbjct: 241 VPYLTSITALVVWLPANPTEKIVRVLFPGNAPQNKILEGLEKLRHLDFLRYPVATQKDLA 300
Query: 301 SGAVPTNLKPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTE 360
SGAVPTNLKPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTE
Sbjct: 301 SGAVPTNLKPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTE 360
Query: 361 KKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEK 420
KKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEK
Sbjct: 361 KKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEK 420
Query: 421 KEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKV 480
KEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKV
Sbjct: 421 KEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKV 480
Query: 481 PGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKR 540
PGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKR
Sbjct: 481 PGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKR 540
Query: 541 EERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVP 600
EERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVP
Sbjct: 541 EERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVP 600
Query: 601 EEQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIEKAELEE 660
EEQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIEKAELEE
Sbjct: 601 EEQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIEKAELEE 660
Query: 661 MEEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFGGRELGLQGKAPEKETSLFLS 720
MEEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFGGRELGLQGKAPEKETSLFLS
Sbjct: 661 MEEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFGGRELGLQGKAPEKETSLFLS 720
Query: 721 SLTTPAGATEHVSYIQDETIPGYSETEQTISDEEIHDEPEERPAPPRFHTSTYDLPGPEG 780
SLTTPAGATEHVSYIQDETIPGYSETEQTISDEEIHDEPEERPAPPRFHTSTYDLPGPEG
Sbjct: 721 SLTTPAGATEHVSYIQDETIPGYSETEQTISDEEIHDEPEERPAPPRFHTSTYDLPGPEG 780
Query: 781 AGPFEASQPADSAVPATSGKVYGTPETELTYPTNIVAAPLAEEEHVSSATSITECDKLSS 840
AGPFEASQPADSAVPATSGKVYGTPETELTYPTNIVAAPLAEEEHVSSATSITECDKLSS
Sbjct: 781 AGPFEASQPADSAVPATSGKVYGTPETELTYPTNIVAAPLAEEEHVSSATSITECDKLSS 840
Query: 841 FATSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEATQGLDYVPSAGTISPTSS 900
FATSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEATQGLDYVPSAGTISPTSS
Sbjct: 841 FATSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEATQGLDYVPSAGTISPTSS 900
Query: 901 LEEDKGFKSPPCEDFSVTGESEKRGEIIGKGLSGERAVEEEEEETANVEMSEKLCSQYGT 960
LEEDKGFKSPPCEDFSVTGESEKRGEIIGKGLSGERAVEEEEEETANVEMSEKLCSQYGT
Sbjct: 901 LEEDKGFKSPPCEDFSVTGESEKRGEIIGKGLSGERAVEEEEEETANVEMSEKLCSQYGT 960
Query: 961 PVFSAPGHALHPGEPALGEAEERCLSPDDSTVKMASPPPSGPPSATHTPFHQSPVEEKSE 1020
PVFSAPGHALHPGEPALGEAEERCLSPDDSTVKMASPPPSGPPSATHTPFHQSPVEEKSE
Sbjct: 961 PVFSAPGHALHPGEPALGEAEERCLSPDDSTVKMASPPPSGPPSATHTPFHQSPVEEKSE 1020
Query: 1021 PQDFQEADSWGDTKRTPGVGKEDAAEETVKPGPEEGTLEKEEKVPPPRSPQAQEAPVNID 1080
PQDFQEADSWGDTKRTPGVGKEDAAEETVKPGPEEGTLEKEEKVPPPRSPQAQEAPVNID
Sbjct: 1021 PQDFQEADSWGDTKRTPGVGKEDAAEETVKPGPEEGTLEKEEKVPPPRSPQAQEAPVNID 1080
Query: 1081 EGLTGCTIQLLPAQDKAIVFEIMEAGEPTGPILGAEALPGGLRTLPQEPGKPQKDEVLRY 1140
EGLTGCTIQLLPAQDKAIVFEIMEAGEPTGPILGAEALPGGLRTLPQEPGKPQKDEVLRY
Sbjct: 1081 EGLTGCTIQLLPAQDKAIVFEIMEAGEPTGPILGAEALPGGLRTLPQEPGKPQKDEVLRY 1140
Query: 1141 PDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRWPEVSPEDTQSLSLS 1200
PDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRWPEVSPEDTQSLSLS
Sbjct: 1141 PDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRWPEVSPEDTQSLSLS 1200
Query: 1201 EESPSKETSLDVSSKQLSPESLGTLQFGELNLGKEEMGHLMQAEDTSHHTAPMSVPEPHA 1260
EESPSKETSLDVSSKQLSPESLGTLQFGELNLGKEEMGHLMQAEDTSHHTAPMSVPEPHA
Sbjct: 1201 EESPSKETSLDVSSKQLSPESLGTLQFGELNLGKEEMGHLMQAEDTSHHTAPMSVPEPHA 1260
Query: 1261 ATASPPTDGTTRYSAQTDITDDSLDRKSPASSFSHSTPSGNGKYLPGAITSPDEHILTPD 1320
ATASPPTDGTTRYSAQTDITDDSLDRKSPASSFSHSTPSGNGKYLPGAITSPDEHILTPD
Sbjct: 1261 ATASPPTDGTTRYSAQTDITDDSLDRKSPASSFSHSTPSGNGKYLPGAITSPDEHILTPD 1320
Query: 1321 SSFSKSPESLPGPALEDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVV 1380
SSFSKSPESLPGPALEDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVV
Sbjct: 1321 SSFSKSPESLPGPALEDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVV 1380
Query: 1381 EPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKD 1440
EPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKD
Sbjct: 1381 EPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKD 1440
Query: 1441 KALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALD 1500
KALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALD
Sbjct: 1441 KALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALD 1500
Query: 1501 QKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQ 1560
QKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQ
Sbjct: 1501 QKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQ 1560
Query: 1561 KDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKA 1620
KDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKA
Sbjct: 1561 KDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKA 1620
Query: 1621 LGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDN 1680
LGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDN
Sbjct: 1621 LGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDN 1680
Query: 1681 RYWRGREDVALEQDTYWRELSCERKVWFPHELDGQGARPHYTEERESTFLDEGPDDEQEV 1740
RYWRGREDVALEQDTYWRELSCERKVWFPHELDGQGARPHYTEERESTFLDEGPDDEQEV
Sbjct: 1681 RYWRGREDVALEQDTYWRELSCERKVWFPHELDGQGARPHYTEERESTFLDEGPDDEQEV 1740
Query: 1741 PLREHATRSPWASDFKDFQESSPQKGLEVERWLAESPVGLPPEEEDKLTRSPFEIISPPA 1800
PLREHATRSPWASDFKDFQESSPQKGLEVERWLAESPVGLPPEEEDKLTRSPFEIISPPA
Sbjct: 1741 PLREHATRSPWASDFKDFQESSPQKGLEVERWLAESPVGLPPEEEDKLTRSPFEIISPPA 1800
Query: 1801 SPPEMVGQRVPSAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSPA 1860
SPPEMVGQRVPSAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSPA
Sbjct: 1801 SPPEMVGQRVPSAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSPA 1860
Query: 1861 PGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGEREEEG 1920
PGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGEREEEG
Sbjct: 1861 PGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGEREEEG 1920
Query: 1921 RAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQYADIYEQMMLTGLG 1980
RAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQYADIYEQMMLTGLG
Sbjct: 1921 RAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQYADIYEQMMLTGLG 1980
Query: 1981 PACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDTPTFSYAALAG 2040
PACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDTPTFSYAALAG
Sbjct: 1981 PACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDTPTFSYAALAG 2040
Query: 2041 PTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSPSPKESGRSH 2100
PTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSPSPKESGRSH
Sbjct: 2041 PTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSPSPKESGRSH 2100
Query: 2101 WDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPS 2160
WDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPS
Sbjct: 2101 WDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPS 2160
Query: 2161 LDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEV 2220
LDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEV
Sbjct: 2161 LDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEV 2220
Query: 2221 TKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFSPSLE 2280
TKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFSPSLE
Sbjct: 2221 TKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFSPSLE 2280
Query: 2281 AAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLECS 2340
AAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLECS
Sbjct: 2281 AAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLECS 2340
Query: 2341 EAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAACPAWERGAWPEGAERS 2400
EAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAACPAWERGAWPEGAERS
Sbjct: 2341 EAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAACPAWERGAWPEGAERS 2400
Query: 2401 SRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPPLPPS 2460
SRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPPLPPS
Sbjct: 2401 SRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPPLPPS 2460
Query: 2461 IDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPPTSASDSGSSQSDSDVPPETE 2520
IDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPPTSASDSGSSQSDSDVPPETE
Sbjct: 2461 IDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPPTSASDSGSSQSDSDVPPETE 2520
Query: 2521 ECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRPDVCMA 2580
ECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRPDVCMA
Sbjct: 2521 ECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRPDVCMA 2580
Query: 2581 DPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASPARRLDLRGKRSPTPGKGPADRA 2640
DPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASPARRLDLRGKRSPTPGKGPADRA
Sbjct: 2581 DPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASPARRLDLRGKRSPTPGKGPADRA 2640
Query: 2641 SRAPPRPRSTTSQVTPAEEKDGHSPMSKGLVNGLKAGPMALSSKGSSGAPVYVDLAYIPN 2700
SRAPPRPRSTTSQVTPAEEKDGHSPMSKGLVNGLKAGPMALSSKGSSGAPVYVDLAYIPN
Sbjct: 2641 SRAPPRPRSTTSQVTPAEEKDGHSPMSKGLVNGLKAGPMALSSKGSSGAPVYVDLAYIPN 2700
Query: 2701 HCSGKTADLDFFRRVRASYYVVSGNDPANGEPSRAVLDALLEGKAQWGENLQVTLIPTHD 2760
HCSGKTADLDFFRRVRASYYVVSGNDPANGEPSRAVLDALLEGKAQWGENLQVTLIPTHD
Sbjct: 2701 HCSGKTADLDFFRRVRASYYVVSGNDPANGEPSRAVLDALLEGKAQWGENLQVTLIPTHD 2760
Query: 2761 TEVTREWYQQTHEQQQQLNVLVLASSSTVVMQDESFPACKIEF 2803
TEVTREWYQQTHEQQQQLNVLVLASSSTVVMQDESFPACKIEF
Sbjct: 2761 TEVTREWYQQTHEQQQQLNVLVLASSSTVVMQDESFPACKIEF 2803
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 681 bits (1757), Expect = 0.0
Identities = 683/2325 (29%), Positives = 1000/2325 (43%), Gaps = 497/2325 (21%)
Query: 1 MDGVAEFSEYVSETVDVPSPFDLLEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNI 60
M+G++EF+EY+SE+V+VPSPFD+LEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFN+
Sbjct: 223 MEGLSEFTEYLSESVEVPSPFDILEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNM 282
Query: 61 LVDGGSDRKSCFWKLVRHLDRIDSVLLTHIGADNLPGINGLLQRKVAELEEEQSQGSSSY 120
L++GGS+RKSCFWKL+RHLDR+DS+LLTHIG DNLPGIN +LQRK+AELEEEQSQGS++
Sbjct: 283 LINGGSERKSCFWKLIRHLDRVDSILLTHIGDDNLPGINSMLQRKIAELEEEQSQGSTTN 342
Query: 121 SDWVKNLISPELGVVFFNVPEKLRLPDASRKAKRSIEEACLTLQHLNRLGIQAEPLYRVV 180
SDW+KNLISP+LGVVF NVPE L+ P+ + K KRSIEEAC TLQ+LN+L ++ EPL+R V
Sbjct: 343 SDWMKNLISPDLGVVFLNVPENLKNPEPNIKMKRSIEEACFTLQYLNKLSMKPEPLFRSV 402
Query: 181 SNTIEPLTLFHKMGVGRLDMYVLNPVKDSKEMQFLMQKWAGNSKAKTGIVLPNGKEAEIS 240
NTI+P+ LF KMGVG+L+MYVLNPVK SKEMQ+ MQ+W G +K K +LPNG+E ++
Sbjct: 403 GNTIDPVILFQKMGVGKLEMYVLNPVKSSKEMQYFMQQWTGTNKDKAEFILPNGQEVDLP 462
Query: 241 VPYLTSITALVVWLPANPTEKIVRVLFPGNAPQNKILEGLEKLRHLDFLRYPVATQKDLA 300
+ YLTS+++L+VW PANP EKI+RVLFPGN+ Q ILEGLEKL+HLDFL+ P+ATQKDL
Sbjct: 463 ISYLTSVSSLIVWHPANPAEKIIRVLFPGNSTQYNILEGLEKLKHLDFLKQPLATQKDL- 521
Query: 301 SGAVPTN-LKPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKT 359
+G VPT +K +K+KQRADS+ESLK K SK + R+E EE + + ++ K
Sbjct: 522 TGQVPTPVVKQTKLKQRADSRESLKPAAKPLPSK-SVRKESKEETPEVTKVNHVEKPPKV 580
Query: 360 EKKAK---------ESSEKP----PEKPAK--PERVKTESSEAL------KAEKRKLI-- 396
E K K ++ KP E P+K P VK E +E KA K K +
Sbjct: 581 ESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKK 640
Query: 397 ----------------KDKVGKKHLKEKISKLEE-KKDKEKKEIKKE---------RKEL 430
K +V KK K I K E+ KK++ KKE+KKE +KE+
Sbjct: 641 ETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEV 700
Query: 431 KKDEGRKEEKKDAKKEEKR------KDTKPELKKISKPDLKPFTP--EVRK-TLYKAKVP 481
KK+ KE KK+ KKEEK+ K+ K E+KK+ K K TP E +K K KVP
Sbjct: 701 KKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVP 760
Query: 482 -------------------GRVKIDRSRAIRGEKELSS--EPQTPPAQKGTVPLPTISGH 520
G++K+ + E ++ T A + I
Sbjct: 761 KKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIGPA 820
Query: 521 REL-----VLSSPEDLTQDFEEMKREE---------RALLAEQRDTGLGDKPF------- 559
+EL ++SSPEDLT+DFEE+K EE + L E + +P
Sbjct: 821 KELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIKPQLELIEDEEKLKETEPVEAYVIQK 880
Query: 560 -------PLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPE--------EQG 604
P ++ +EG +T +G P EE EK+ V ++ + E+
Sbjct: 881 EREVTKGPAESPDEGITTTEGEGECEQTP----EELEPVEKQGVDDIEKFEDEGAGFEES 936
Query: 605 SKDRGLDSGAETEEEKDTWEEKKQR------EAERLPDRTEAREESEPEVKE-------- 650
S+ + AETEE ++ E+ ++ + D A+ E++ ++E
Sbjct: 937 SETGDYEEKAETEEAEEPEEDGEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVASG 996
Query: 651 ---------DVIEKAELEEMEEVHPSDEEEEDATKAEGFYQKHMQEP--LKVTPRSREAF 699
+ IEK E E+ EE +++ EDA + E +K E + V ++ EA
Sbjct: 997 DDRAEEDMDEAIEKGEAEQSEEEADEEDKAEDAREEEYEPEKMEAEDYVMAVVDKAAEA- 1055
Query: 700 GGRELGLQGKAPEKETSLFLSSLTTPAGA----TEHVSYIQDETIPGYSETEQTISDEE- 754
GG E E FL++ T GA E S I DET+PG SE+E T SDEE
Sbjct: 1056 GGAE----------EQYGFLTTPTKQLGAQSPGREPASSIHDETLPGGSESEATASDEEN 1105
Query: 755 IHDEPEERPAPPRFHTSTYDLPGPEGAGPFEASQPADSAVPATSGKVYGTPETELTYPTN 814
D+PEE A + ST ++ +S+P TP E++ P +
Sbjct: 1106 REDQPEEFTATSGYTQSTIEI----------SSEP--------------TPMDEMSTPRD 1141
Query: 815 IVAAPLAEEEHVSSATSITECDKLSSFATSVAEDQSVASLTAPQTEETGKSSLLLDTVTS 874
+++ EE S + K S S S A T G S
Sbjct: 1142 VMSDETNNEETESPSQEFVNITKYESSLYS-----QEYSKPADVTPLNGFSE-------- 1188
Query: 875 IPSSRTEATQGLDYVPSAGTISPTSSLEEDKGFKSPPCEDFSVTGESEKRGEIIGKGLSG 934
S+T+AT G DY SA TISP SS+EEDK +S + + SE + L
Sbjct: 1189 --GSKTDATDGKDYNASASTISPPSSMEEDKFSRSALRDAYC----SEVKASTT---LDI 1239
Query: 935 ERAVEEEEEETANVEMSEKLCSQYGTPVFSAP------GHALHPGE----------PALG 978
+ ++ E + S L +P+ P +L P E P
Sbjct: 1240 KDSISAVSSEKVSPSKSPSLSPSPPSPLEKTPLGERSVNFSLTPNEIKVSAEAEVAPVSP 1299
Query: 979 E-----AEERCLSPDDSTVKMASPPPSGPPSATHTPFHQSPVEEKSE------------- 1020
E EE C SP+D T+++ SP S SA HTP++QSP +EKS
Sbjct: 1300 EVTQEVVEEHCASPEDKTLEVVSPSQSVTGSAGHTPYYQSPTDEKSSHLPTEVIEKPPAV 1359
Query: 1021 PQDFQEADSWGDTKRT-------PGVGKEDAAEETVKP--GP----EEGTLEKEEKVPPP 1067
P F+ +D+ + +R P E E+ + P P E E
Sbjct: 1360 PVSFEFSDAKDENERASVSPMDEPVPDSESPIEKVLSPLRSPPLIGSESAYESFLSADDK 1419
Query: 1068 RSPQAQEAPVNIDEGLTGCTIQLLPAQD--KAIVFEIMEAGEPT--GPI---LGAEALPG 1120
S + E+P G G Q+ P + +++ + G+ T PI G E
Sbjct: 1420 ASGRGAESPFEEKSGKQGSPDQVSPVSEMTSTSLYQDKQEGKSTDFAPIKEDFGQEKKTD 1479
Query: 1121 GLRTLPQEPG-----------KPQKDEVLRY----------------PDRSLSPED---- 1149
+ + +P P + +V ++ D+S +P D
Sbjct: 1480 DVEAMSSQPALALDERKLGDVSPTQIDVSQFGSFKEDTKMSISEGTVSDKSATPVDEGVA 1539
Query: 1150 --------------AESLSVLSVPSPDTANQEPTPKSPCGL------------------- 1176
S++ S P P T + P+ + G
Sbjct: 1540 EDTYSHMEGVASVSTASVATSSFPEPTTDDVSPSLHAEVGSPHSTEVDDSLSVSVVQTPT 1599
Query: 1177 ----TEQYLHKDRW--------PEVSPEDTQSLSLSEESPSKETSLDVSSKQLSPESLGT 1224
TE K+ P+ SP+ +S + ++ S+++S+ + Q SPE
Sbjct: 1600 TFQETEMSPSKEECPRPMSISPPDFSPKTAKSRTPVQDHRSEQSSMSIEFGQESPEQSLA 1659
Query: 1225 LQFGELNLGKEEMG----HLMQAEDTSHHTAPMSVPEPHAATASPPTDGTTRYSAQTDIT 1280
+ F + +G H+ + T +P + + + PP + + Y+ D++
Sbjct: 1660 MDFSRQSPDHPTVGAGVLHITENGPTEVDYSPSDMQDSSLSHKIPPMEEPS-YTQDNDLS 1718
Query: 1281 DDSLDRKSPASSFSHSTPSGNGKYLPGAITSP-DEHILTP-----DSSFSKSPESLPGPA 1334
+ + S ++PS + + P I SP E L+ D S S S +
Sbjct: 1719 E------LISVSQVEASPSTSSAHTPSQIASPLQEDTLSDVAPPRDMSLYASLTSEKVQS 1772
Query: 1335 LEDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLE-HKEVVEPKDTAIYQKDEA 1393
LE + + + L R S P D K+KT H P D A +
Sbjct: 1773 LEGEKLSPKSDISPLTPRESSPLYSPTFSDSTSAVKEKTATCHSSSSPPIDAASAEPYGF 1832
Query: 1394 LHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEK 1453
Q AL RDL LE+ P D + PEE
Sbjct: 1833 RASVLFDTMQHHLAL---NRDL--STPGLEKDSGGKTPGD---------FSYAYQKPEET 1878
Query: 1454 DKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPED 1513
++ +++D E +K D +++ E+ K P D + K PED
Sbjct: 1879 TRSPDEEDYDYESYEKTTRTSDVGGYYYEKI-ERTTKSP--SDSGYSYETIGKTTKTPED 1935
Query: 1514 TVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALE 1573
+ +E+T + PE+ + + +SEK E ++ +K E + + +
Sbjct: 1936 --GDYSYEIIEKTTRTPEEGGYSYD----ISEKTTSPPEVSGYSY-EKTERSRRLLDDIS 1988
Query: 1574 ENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRA 1633
+ E D + ++ EK+ + E EG +
Sbjct: 1989 NGYDDSEDGGHTLGDPS-----YSYETTEKITSFPE-------------------SEGYS 2024
Query: 1634 REQEEKYWRGQDVVQEWQET------SPTREEPAGEQKELAPAWEDTSPEQDNRYWRGRE 1687
E K R D ET +P + E +L E SP + R+
Sbjct: 2025 YETSTKTTRTPDTSTYCYETAEKITRTPQASTYSYETSDLCYTAEKKSPSE------ARQ 2078
Query: 1688 DVALEQDTYWRELSCERKVWFPH-ELDGQGARPHYTEERESTFLDEGPDDEQEVPLREHA 1746
DV L SCE K P EL P+ E F E P +E E PL +
Sbjct: 2079 DVDL-----CLVSSCEYK--HPKTELSPSFINPNPLE----WFASEEPTEESEKPLTQSG 2127
Query: 1747 TRSPWASDFKDFQESSPQKGLEVERWLAESPVGLPPEEEDKLTRSPFEIISPPASPPEMV 1806
P P G + R E +PP V
Sbjct: 2128 GAPP------------PPGGKQQGRQCDE-------------------------TPPTSV 2150
Query: 1807 GQRVPSAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSPAPGPPTP 1866
+ PS + P P+ + P + + S D +P D+ + + P P P
Sbjct: 2151 SESAPSQTDSDVP-PETEECPSITADANIDS--EDESETIPTDKTVTYKHMDPPPAP--- 2204
Query: 1867 APESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGERE--EEGRAEA 1924
+ +P+P + D A+++ + L KD ++ ++ + ++ +
Sbjct: 2205 -VQDRSPSPRHPDVSMVDPEALAIEQNLGK-------ALKKDLKEKTKTKKPGTKTKSSS 2256
Query: 1925 PDKSSHSSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQYADIYEQMMLTGLGPACP 1984
P K S P A+ E ++ R +P E S + A A P
Sbjct: 2257 PVKKSDGKSKPLAASPKPAGLKESSDKVSRVASPKKKE-SVEKA-------------AKP 2302
Query: 1985 TREPPLGAAGDWPPCLSTKEAA-AGRNTSAEKELSSPISPKSLQS 2028
T P + AA TK AA A + SA+ + P + K+ +S
Sbjct: 2303 TTTPEVKAARGEEKDKETKNAANASASKSAKTATAGPGTTKTTKS 2347
Score = 322 bits (824), Expect = 4e-87
Identities = 201/409 (49%), Positives = 248/409 (60%), Gaps = 43/409 (10%)
Query: 2423 PSSASPEVEAGPQGCATEPRPHRGELSPSFLNP-PLPPSIDDRDLSTEEVRLVGRGGRRR 2481
PS A +V+ P + ELSPSF+NP PL + E L GG
Sbjct: 2073 PSEARQDVDLCLVSSCEYKHP-KTELSPSFINPNPLEWFASEEPTEESEKPLTQSGGAPP 2131
Query: 2482 VGGPGTTGGPCPVTDETPPTSASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLP 2541
G G C DETPPTS S+S SQ+DSDVPPETEECPSITA+A +DS+++ + +P
Sbjct: 2132 PPGGKQQGRQC---DETPPTSVSESAPSQTDSDVPPETEECPSITADANIDSEDESETIP 2188
Query: 2542 VDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKV 2601
DK V+ H DPPP P D PSP PDV M DPE L+ E + L K+ +
Sbjct: 2189 TDKT--VTYKHM-----DPPPAPVQDRSPSPRHPDVSMVDPEALAIEQNLGKAL--KKDL 2239
Query: 2602 QGRVGRRAPG-KAKPASPARRLDLRGK---RSPTPG--KGPADRASR-APPRPR------ 2648
+ + + PG K K +SP ++ D + K SP P K +D+ SR A P+ +
Sbjct: 2240 KEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAGLKESSDKVSRVASPKKKESVEKA 2299
Query: 2649 ---STTSQVTPA--EEKD------GHSPMSKGLVNGLKAGPMALSSKGSS----GAPVYV 2693
+TT +V A EEKD ++ SK AGP + SS G PVY+
Sbjct: 2300 AKPTTTPEVKAARGEEKDKETKNAANASASKSAKTAT-AGPGTTKTTKSSAVPPGLPVYL 2358
Query: 2694 DLAYIPNHCSGKTADLDFFRRVRASYYVVSGNDPANGEPSRAVLDALLEGKAQWGENLQV 2753
DL YIPNH + K D++FF+RVR+SYYVVSGNDPA EPSRAVLDALLEGKAQWG N+QV
Sbjct: 2359 DLCYIPNHSNSKNVDVEFFKRVRSSYYVVSGNDPAAEEPSRAVLDALLEGKAQWGSNMQV 2418
Query: 2754 TLIPTHDTEVTREWYQQTHEQQQQLNVLVLASSSTVVMQDESFPACKIE 2802
TLIPTHD+EV REWYQ+THE+QQ LN++VLASSSTVVMQDESFPACKIE
Sbjct: 2419 TLIPTHDSEVMREWYQETHEKQQDLNIMVLASSSTVVMQDESFPACKIE 2467
Score = 67.0 bits (162), Expect = 2e-10
Identities = 282/1270 (22%), Positives = 467/1270 (36%), Gaps = 279/1270 (21%)
Query: 1336 EDIAIKWEDKVPGLKDRTSEQKKEPEP-KDEVLQQ----------KDKTLEHKEVVEPKD 1384
+D IK E K P + ++ K+EP P K EV ++ K+KT++ + V+P+D
Sbjct: 590 KDKPIKTETK-PSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPED 648
Query: 1385 TAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALE-----QKDKALEPKD------ 1433
+K+E K E K++DK +K ++++ E +K++ EPK
Sbjct: 649 ----KKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKET 704
Query: 1434 --KDLEEKDKALEQKDKIPEEKD---------KALEQKDTALEQ--KDKALEPKDKDLEQ 1480
K+++++ K E+K+ EEK+ K ++ T L + K AL+PK E+
Sbjct: 705 PPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEE 764
Query: 1481 ---KDRVLEQKEKIPEEKDKALDQKVRSVEHKAPE----------DTVAEMKDRDLEQTD 1527
KD V K P+EK K KV E KA E T A M +
Sbjct: 765 SVKKDSVAAGK---PKEKGKI---KVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIG 818
Query: 1528 KAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQE 1587
A E + ++ +S +D L + + L ++ + ++I+ + E + E
Sbjct: 819 PAKE----LEAERSLMSSPED--LTKDFEELKAEEVDVTKDIK--------PQLELIEDE 864
Query: 1588 DKTRKPKMLE----EKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRG 1643
+K ++ + +E +K E K E + + T+ G E +E E EK +G
Sbjct: 865 EKLKETEPVEAYVIQKEREVTKGPAESPDEGITTTEGEGECEQTPEE---LEPVEK--QG 919
Query: 1644 QDVVQEWQETSPTREEPA--GEQKELAPAWEDTSPEQDNRYWRGREDVALEQDTYWRELS 1701
D ++++++ EE + G+ +E A E PE+D G E V + +
Sbjct: 920 VDDIEKFEDEGAGFEESSETGDYEEKAETEEAEEPEED-----GEEHVCVS--------A 966
Query: 1702 CERKVWFPHELDGQGARPHYTEERESTFL--DEGPDDEQEVPLREHATRSPWASDFKDFQ 1759
+ E A + E+RES D +D E + A +S +D +D
Sbjct: 967 SKHSPTEDEESAKAEADAYIREKRESVASGDDRAEEDMDEAIEKGEAEQSEEEADEEDKA 1026
Query: 1760 ESSPQKGLEVERWLAESPVGLPPEEEDKLTRSPFEIISPPASPPEMVGQRVPSAPGQE-- 1817
E + ++ E E+ AE V + ++ E +P + +G + +PG+E
Sbjct: 1027 EDAREEEYEPEKMEAEDYV-MAVVDKAAEAGGAEEQYGFLTTPTKQLGAQ---SPGREPA 1082
Query: 1818 SPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSPAPG----------PPTPA 1867
S I D L ++E T ++R P + G PTP
Sbjct: 1083 SSIHDETLPGGSESEATASD---------EENREDQPEEFTATSGYTQSTIEISSEPTPM 1133
Query: 1868 PESHTPAPFSWGTAEYDSVVAAVQE--GAAELEGGPYSPLGKDYRKAEGEREEEGRAEAP 1925
E TP + + QE + E YS ++Y K G +E
Sbjct: 1134 DEMSTPRDVMSDETNNEETESPSQEFVNITKYESSLYS---QEYSKPADVTPLNGFSEGS 1190
Query: 1926 DKSSHSSKVPEASKSHATTEPEQTEPEQREPTPYPDE-----RSFQYADIYEQMMLTGLG 1980
+ K AS S + P E ++ + D ++ DI + +
Sbjct: 1191 KTDATDGKDYNASAS-TISPPSSMEEDKFSRSALRDAYCSEVKASTTLDIKDSISAVSSE 1249
Query: 1981 PACPTREPPLGAAGDWPPCLSTKEAAAGRN-----------TSAEKELSSPISP------ 2023
P++ P L + PP K R+ SAE E+ +P+SP
Sbjct: 1250 KVSPSKSPSLSPS---PPSPLEKTPLGERSVNFSLTPNEIKVSAEAEV-APVSPEVTQEV 1305
Query: 2024 ----------KSLQSDTPTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGP 2073
K+L+ +P+ S AG T + P+ E S P ++ K P
Sbjct: 1306 VEEHCASPEDKTLEVVSPSQSVTGSAGHTPYYQ---SPTDEKSSHLP-----TEVIEKPP 1357
Query: 2074 SPPLNGNILSCSP--DRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPHPI 2131
+ P++ +R S SP ++P +++SP
Sbjct: 1358 AVPVSFEFSDAKDENERASVSP---------------------MDEPVPDSESPIEKVLS 1396
Query: 2132 PMGSPTLWPETEAHVSPPLDSHLGPARPSLDFPASAFGF-------SSLQPAPPQLPSPA 2184
P+ SP L A+ +S L S D AS G S Q +P Q+ +
Sbjct: 1397 PLRSPPLIGSESAY-----ESFL-----SADDKASGRGAESPFEEKSGKQGSPDQVSPVS 1446
Query: 2185 EPRSAPCGSLAFSGDRALALAP-----GPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSP 2239
E S G ++ AP G +T E + A +LD SP+
Sbjct: 1447 EMTSTSLYQDKQEG-KSTDFAPIKEDFGQEKKTDDVEAMSSQPALALDERKLGDVSPTQI 1505
Query: 2240 GAPLLSNLPRPASPALSEGS-SSEATTPVISSVAERFSPSLEAAEQESGELDPGMEPAAH 2298
+ ++SEG+ S ++ TPV VAE +E A+
Sbjct: 1506 DVSQFGSFKEDTKMSISEGTVSDKSATPVDEGVAEDTYSHMEGV-------------ASV 1552
Query: 2299 SLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLE----CSEAATEKPSPFQ--- 2351
S + S P + D+ +PSL ++G P E S + + P+ FQ
Sbjct: 1553 STASVATSSFPEPTTDDV----SPSLHAEVGS---PHSTEVDDSLSVSVVQTPTTFQETE 1605
Query: 2352 -VPS-EDCAANGPTETSPNPPGPAPAKAENEEAAACPAWERGAW-----PEGAERSSRPD 2404
PS E+C P S +PP +P A++ E+ + E E+S D
Sbjct: 1606 MSPSKEEC----PRPMSISPPDFSPKTAKSRTPVQDHRSEQSSMSIEFGQESPEQSLAMD 1661
Query: 2405 -TLLSPEQPVCPAG----GSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPPL-- 2457
+ SP+ P AG GP EV+ P H+ PP+
Sbjct: 1662 FSRQSPDHPTVGAGVLHITENGP-----TEVDYSPSDMQDSSLSHK--------IPPMEE 1708
Query: 2458 PPSIDDRDLS 2467
P D DLS
Sbjct: 1709 PSYTQDNDLS 1718
Score = 34.3 bits (77), Expect = 1.8
Identities = 34/137 (24%), Positives = 48/137 (35%), Gaps = 14/137 (10%)
Query: 340 VVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDK 399
+V+ A L K L K + K K ++KP K VK K++
Sbjct: 2219 MVDPEALAIEQNLGKALKK-DLKEKTKTKKPGTKTKSSSPVKKSDG---KSKPLAASPKP 2274
Query: 400 VGKKHLKEKISKLEEKKDKEK----------KEIKKERKELKKDEGRKEEKKDAKKEEKR 449
G K +K+S++ K KE E+K R E K E + A K K
Sbjct: 2275 AGLKESSDKVSRVASPKKKESVEKAAKPTTTPEVKAARGEEKDKETKNAANASASKSAKT 2334
Query: 450 KDTKPELKKISKPDLKP 466
P K +K P
Sbjct: 2335 ATAGPGTTKTTKSSAVP 2351
>gi|50428935 BPY2 interacting protein 1 [Homo sapiens]
Length = 1059
Score = 293 bits (750), Expect = 2e-78
Identities = 182/392 (46%), Positives = 230/392 (58%), Gaps = 55/392 (14%)
Query: 2 DGVAEFSEYVSETVDVPSPFDLLEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNIL 61
+G+ EF EYV+E+++ PSPF+LLEPPTSGGFL+L +PCCYIFPGG GD+A FAVNGF +L
Sbjct: 205 EGLCEFLEYVAESLEPPSPFELLEPPTSGGFLRLGRPCCYIFPGGLGDAAFFAVNGFTVL 264
Query: 62 VDGGSDRKSCFWKLVRHLDRIDSVLLTHIGADNLPGINGLLQRKVAELEEEQSQGSSSYS 121
V+GGS+ KS FWKLVRHLDR+D+VL+TH GAD+LPG+N LL+RK+AE E + G S+
Sbjct: 265 VNGGSNPKSSFWKLVRHLDRVDAVLVTHPGADSLPGLNSLLRRKLAE-RSEVAAGGGSWD 323
Query: 122 DWVKNLISPELGVVFFNVPEKLRLPDASRKAKRSIEEACLTLQHLNRLGIQAEPLYRVVS 181
D ++ LISP LGVVFFN E A+ + R +EA L L L +LGI PL R
Sbjct: 324 DRLRRLISPNLGVVFFNACE------AASRLARGEDEAELALSLLAQLGITPLPLSR-GP 376
Query: 182 NTIEPLTLFHKMGVGRLDMYVLNPVKDSKEMQFLMQKWAGNSKAKTGIVLPNGKEAEISV 241
+P LF KMGVGRLDMYVL+P E
Sbjct: 377 VPAKPTVLFEKMGVGRLDMYVLHPPSAGAERT---------------------------- 408
Query: 242 PYLTSITALVVWLPANPTEKIVRVLFPGNAPQNKILEGLEKLRHLDFLRYPVATQKDLAS 301
L S+ AL+VW PA P EK+VRVLFPG P +L+GL +L+HL FLR PV T +DL
Sbjct: 409 --LASVCALLVWHPAGPGEKVVRVLFPGCTPPACLLDGLVRLQHLRFLREPVVTPQDLEG 466
Query: 302 GAVPTNLKPSKIKQRADSKESL-KATTKTAVSKLAKREEVVEEGAKEARSELAKELA--K 358
RA+SKES+ + LA +E AR E A+ A K
Sbjct: 467 PG------------RAESKESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRK 514
Query: 359 TEKKAKESSEKPPEKPAKPERVKTESSEALKA 390
TEK+AK E +K KP +T+ E +A
Sbjct: 515 TEKEAKTPREL--KKDPKPSVSRTQPREVRRA 544
Score = 196 bits (498), Expect = 3e-49
Identities = 194/602 (32%), Positives = 259/602 (43%), Gaps = 140/602 (23%)
Query: 2234 PSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFS-PSLEAAEQESGELDPG 2292
PS S G P ++N PR + P+L G +S + S ++ + PSLE +GE
Sbjct: 566 PSTSHSGFPPVANGPR-SPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKAL 624
Query: 2293 MEPAAHSLWDLTPLSPAP-----PASLDLALAPAPSLPGDMGDGILPCHLECSEAATEKP 2347
P A S P +P+P PA L+ +P G+ G
Sbjct: 625 ELPLAASSIP-RPRTPSPESHRSPAEGSERLSLSPLRGGEAG------------------ 665
Query: 2348 SPFQVPSEDCAANGPTETSPNPPGP--APAKAENEEAAACPAWERGAWPEGAERSSRPDT 2405
P PT T+P+ P +P E +E+ + +
Sbjct: 666 -----PDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSF----------------EQ 704
Query: 2406 LLSPEQPVCPAGGS---GGPPS--SASP-EVEAGPQGCATEPRP--HRGELSPSFLNPPL 2457
+L P P AG S GP + SASP +V+ C P HR + P P
Sbjct: 705 VLPPSAPTSEAGLSLPLRGPRARRSASPHDVDL----CLVSPCEFEHRKAV-PMAPAPAS 759
Query: 2458 PPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPPTSASDSGSSQSDSDVPP 2517
P S +D ++E R GG G +ETPPTS S+S + SDSD P
Sbjct: 760 PGSSNDSSARSQE----------RAGGLGA--------EETPPTSVSESLPTLSDSDPVP 801
Query: 2518 ETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRPDV 2577
A A DSDED + V P HDP P P P P P +
Sbjct: 802 --------LAPGAADSDEDTEGFGV-------------PRHDPLPDPLKVPPPLPDPSSI 840
Query: 2578 CMADPEGLSSESGR-VERLREKEKVQGRVGRRAPG-KAKPASPARRLDLRGKRSPTPGKG 2635
CM DPE L ++ R E + K R RA KA P + A+ T G
Sbjct: 841 CMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAK----------TKGLA 890
Query: 2636 PADRASRAPPRPRSTTSQVTPAEEKDGHSPMSKGLVNGLKAGPMALSSKGSSGA------ 2689
DRASR P S S+ + EK G +P+S+ K+ +++G SG+
Sbjct: 891 GGDRASR----PLSARSEPS---EKGGRAPLSR------KSSTPKTATRGPSGSASSRPG 937
Query: 2690 --------PVYVDLAYIPNHCSGKTADLDFFRRVRASYYVVSGNDPANGEPSRAVLDALL 2741
PVY+DLAY+P+ S D +FF+RVRA YV+SG D E RAVLDALL
Sbjct: 938 VSATPPKSPVYLDLAYLPSGSSAHLVDEEFFQRVRALCYVISGQDQRKEEGMRAVLDALL 997
Query: 2742 EGKAQWGENLQVTLIPTHDTEVTREWYQQTHEQQQQLNVLVLASSSTVVMQDESFPACKI 2801
K W +LQVTLIPT D+ WY +TH + Q L + VL S+S V MQD++FPACK+
Sbjct: 998 ASKQHWDRDLQVTLIPTFDSVAMHTWYAETHARHQALGITVLGSNSMVSMQDDAFPACKV 1057
Query: 2802 EF 2803
EF
Sbjct: 1058 EF 1059
Score = 50.8 bits (120), Expect = 2e-05
Identities = 123/497 (24%), Positives = 173/497 (34%), Gaps = 103/497 (20%)
Query: 1916 REEEGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQYADIYEQMM 1975
R+E RAEAP K+ +K P K +T+P + + A +
Sbjct: 503 RKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVR----------RAASSVPNLK 552
Query: 1976 LTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDTPTFSY 2035
T A R+ P + +PP + P SP SL+ +
Sbjct: 553 KTNAQAAPKPRKAPSTSHSGFPPV-----------------ANGPRSPPSLRCGEASPPS 595
Query: 2036 AALAGP----TVPPRPEPGP-------SMEPSLTPPAVP-PRAPILSKGPSPPLNGNILS 2083
AA P P E GP ++E L ++P PR P SP LS
Sbjct: 596 AACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLS 655
Query: 2084 CSPDRRSPSPKESGRSHWDDSTSDSEL--EKGAREQPE-KEAQSPSPPHPIPMGSPTLWP 2140
SP R + ++ + + + L E G+ E E+ S S +P +PT
Sbjct: 656 LSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPT--- 712
Query: 2141 ETEAHVSPPLDSHLGP-ARPS-----LDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSL 2194
+EA +S PL GP AR S +D + + A P P+PA P S+ S
Sbjct: 713 -SEAGLSLPL---RGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSN-DSS 767
Query: 2195 AFSGDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQL----PSPSSPGA--------- 2241
A S +RA L E T S+ SLP L P P +PGA
Sbjct: 768 ARSQERAGGLG------------AEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEG 815
Query: 2242 ---PLLSNLPRP--ASPALSEGSSSEATTPVISSVAERFSP-SLEAAEQESGELDPGMEP 2295
P LP P P L + SS P E P + E S P P
Sbjct: 816 FGVPRHDPLPDPLKVPPPLPDPSSICMVDP------EMLPPKTARQTENVSRTRKPLARP 869
Query: 2296 AAHSLWDLTPLSPAPPASLDLALAPAPSLP-GDMGDGILPCHLECSEAATEKPSPFQVPS 2354
+ + A P + +A A L GD L E SE P + +
Sbjct: 870 NSRA---------AAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSST 920
Query: 2355 EDCAANGPTETSPNPPG 2371
A GP+ ++ + PG
Sbjct: 921 PKTATRGPSGSASSRPG 937
Score = 42.7 bits (99), Expect = 0.005
Identities = 103/476 (21%), Positives = 164/476 (34%), Gaps = 89/476 (18%)
Query: 1719 PHYTEERESTFLDEGPDDEQEVPLREHATRSPWASDFKDFQESSPQKGLEVERWLAESPV 1778
P TE+ T + D + V + AS + ++++ Q + + + S
Sbjct: 512 PRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHS 571
Query: 1779 GLPPEEEDKLTRSPFEIISPPASPPEM-VGQRVPSAPGQESPIPDPKLMPHMKNEPTTPS 1837
G PP + + P SPP + G+ P + SP P ++
Sbjct: 572 GFPP------------VANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLE------- 612
Query: 1838 WLADIPPWVPKDRPLPPAPLSPAPGPPTPAPESH-TPAPFSWGTAEYDSVVAAVQEGAAE 1896
L IP K LP A S P P TP+PESH +PA + + +
Sbjct: 613 -LGPIPAGEEKALELPLAA-SSIPRPRTPSPESHRSPAE------------GSERLSLSP 658
Query: 1897 LEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEA---------SKSHATTE-- 1945
L GG P AE S HS++V E+ S T+E
Sbjct: 659 LRGGEAGPDASPTVTTPTVTTPSLPAEV--GSPHSTEVDESLSVSFEQVLPPSAPTSEAG 716
Query: 1946 ---PEQTEPEQREPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLST 2002
P + +R +P+ + +E + PA P +
Sbjct: 717 LSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPA------PASPGSSNDSSARS 770
Query: 2003 KEAAAGRN------TSAEKELSS-------PISPKSLQSDTPTFSYAA-----LAGPTVP 2044
+E A G TS + L + P++P + SD T + L P
Sbjct: 771 QERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKV 830
Query: 2045 PRPEPGPS----MEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSP--SPKESGR 2098
P P P PS ++P + PP + +S+ P N + +P + +P + K G
Sbjct: 831 PPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAP-KATPVAAAKTKGL 889
Query: 2099 SHWDD-----STSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHVSPP 2149
+ D S EKG R +++ +P P GS + P A +PP
Sbjct: 890 AGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVSA--TPP 943
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 144 bits (363), Expect = 1e-33
Identities = 121/499 (24%), Positives = 248/499 (49%), Gaps = 49/499 (9%)
Query: 1343 EDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVK 1402
E+K+ + R EQ+KE +++ L+++ K E +E ++ ++ +++++E + + E +
Sbjct: 275 EEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMW 334
Query: 1403 QQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDK-------------I 1449
+Q++ L ++ + + +++ + +++ + +D+ L EK++ + +++K I
Sbjct: 335 RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERI 394
Query: 1450 PEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQ-KVRSVEH 1508
E + K E+++T EQ++K + ++ EQ+++ +Q +++PE+K+K +Q K++ E
Sbjct: 395 REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQ-QRLPEQKEKLWEQEKMQEQEE 453
Query: 1509 KAPEDTVAEMKDRDLEQ---TDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEAL 1565
K E E K RD E+ +K ++ + +EQ+D++ E++++ +Q+ Q++
Sbjct: 454 KIWEQ---EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMW 510
Query: 1566 EQNIQALEENHQTQEQESL-VQEDKTRKPKMLEEKSPEKVKAMEEKL---EALLEKTKAL 1621
EQ+ + E+ + +EQ+ + QE+K R+ K +E+ +K EEK+ E + E+ K +
Sbjct: 511 EQDERLREKEERMREQKKMWQQEEKMREEKKTQEQE-KKTWDQEEKMREEERMREREKKM 569
Query: 1622 GLEESLV---------QEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWE 1672
EE ++ QE + REQEEK W ++ +QE +E +EE EQ+E E
Sbjct: 570 REEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE-----E 624
Query: 1673 DTSPEQDNRYWRGREDVALEQDTYWRE---LSCERKVWFPHELDGQGARPHYTEERESTF 1729
D EQ+ W E + +++ W + + + + E QG E+ E
Sbjct: 625 DKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQ 684
Query: 1730 LDEGPDDEQEVPLREHATRSPWASDFKDFQESSPQKGLEVERWLAESPVGLPPEEEDKLT 1789
E EQE +R + W + K + + G E R E + ++E
Sbjct: 685 GQEEKMREQEEKMRGQEEKM-WGQEEKMWGQEEKMWGQEEMR---EKEERIRDQKEKMQE 740
Query: 1790 RSP--FEIISPPASPPEMV 1806
R P E S P PP V
Sbjct: 741 RLPEHEERCSEPCLPPSKV 759
Score = 134 bits (337), Expect = 1e-30
Identities = 100/411 (24%), Positives = 213/411 (51%), Gaps = 27/411 (6%)
Query: 1355 EQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRD 1414
+++K ++ + +Q+ K E +E + ++ + ++++ L + + +++Q K EQ+ +
Sbjct: 253 QEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQM 312
Query: 1415 LEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPK 1474
EQ++ EQ++K E ++K ++++ EQ+ ++ E++ K +Q++ EQ D+ L K
Sbjct: 313 QEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ-DERLREK 371
Query: 1475 DKDLEQKDRVLEQKEKIPEE--------KDKALDQKVRSVEHK--APEDTVAEMKDRDLE 1524
++ + +++++ EQ+EK+ EE K + ++ +R E K E+ + E ++++ +
Sbjct: 372 EERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQ 431
Query: 1525 QTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESL 1584
Q + PEQK + EQ +K+ E++++ EQ+ Q++ ++ +E + QE +
Sbjct: 432 Q-QRLPEQKEKLWEQ-EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 489
Query: 1585 VQEDKTRKPKM----LEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKY 1640
QE+K R + EE+ E+ + + EK E + E+ K EE + +E + +EQE+K
Sbjct: 490 EQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKT 549
Query: 1641 W------RGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQD 1694
W R ++ ++E ++ EE EQ+E E+ EQ+ + W E + +++
Sbjct: 550 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609
Query: 1695 TYWRELSCERKVWFPHELDGQGARPHYTEERESTFLD-EGPDDEQEVPLRE 1744
W + E K+W E D + E+E + E EQE +RE
Sbjct: 610 KMWEQ---EEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMRE 657
Score = 131 bits (329), Expect = 1e-29
Identities = 92/324 (28%), Positives = 181/324 (55%), Gaps = 34/324 (10%)
Query: 1340 IKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNE 1399
I+ ++++ G + + Q+K E +D++ +Q++K + ++ + ++ ++++DE L K E
Sbjct: 462 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEE 521
Query: 1400 AVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQ 1459
+++Q K +Q+ + E+K T EQ+ K + ++K + E+++ E++ K+ EE++ EQ
Sbjct: 522 RMREQKKMWQQEEKMREEKKTQ-EQEKKTWDQEEK-MREEERMREREKKMREEEEMMREQ 579
Query: 1460 KDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMK 1519
++ EQ++K E ++K EQ++++ EQ+EK+ E+++K +Q+ ED + E +
Sbjct: 580 EEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE--------EEDKMQEQE 631
Query: 1520 DRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQ 1579
+ EQ +K EQ+ + EQ++K+ E++++ EQ+ GQ+++ EQ EE Q Q
Sbjct: 632 EMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQ-----EEKMQGQ 686
Query: 1580 EQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEK 1639
E++ QE+K R + EK+ EEK+ ++ K G EE +E R R+Q+EK
Sbjct: 687 EEKMREQEEKMRGQE-------EKMWGQEEKMWG--QEEKMWGQEEMREKEERIRDQKEK 737
Query: 1640 YWRGQDVVQEWQETSPTREEPAGE 1663
QE P EE E
Sbjct: 738 ----------MQERLPEHEERCSE 751
Score = 129 bits (323), Expect = 5e-29
Identities = 98/358 (27%), Positives = 194/358 (54%), Gaps = 26/358 (7%)
Query: 1336 EDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALH 1395
E+ + E+K+ ++ EQ+++ + + +QK+K E +E ++ ++ I++++E +
Sbjct: 405 EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE-QEKMQEQEEKIWEQEEKIR 463
Query: 1396 VKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDK 1455
+ E Q+ K Q+ + EQ+D EQ++K + + K +++++ EQ +++ E++++
Sbjct: 464 DQEEMWGQEKKMWRQE-KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEER 522
Query: 1456 ALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKI-PEEKDKALDQKVRSVEH--KAPE 1512
EQK + Q+++ + + K EQ+ + +Q+EK+ EE+ + ++K+R E + E
Sbjct: 523 MREQK--KMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 580
Query: 1513 DTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQAL 1572
+ + E +++ EQ +K EQ+ + QEQ++K+ E+ E+K W ++D+ EQ
Sbjct: 581 EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ-----EEKMWEQEEEDKMQEQEEMMW 635
Query: 1573 EENHQTQEQESLV--QEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESL-VQ 1629
E+ + QEQE + QE+K R+ + + EK++ EEK+ EK + G EE + Q
Sbjct: 636 EQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQ--GQEEKMREQ 693
Query: 1630 EGRAREQEEKYWR------GQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNR 1681
E + R QEEK W GQ+ QE +EE +QKE ++ PE + R
Sbjct: 694 EEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKE---KMQERLPEHEER 748
Score = 127 bits (319), Expect = 2e-28
Identities = 105/445 (23%), Positives = 217/445 (48%), Gaps = 38/445 (8%)
Query: 1355 EQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRD 1414
E K++ E +L Q +E+ ++ Q+ + + + +Q+++ EQ+G+
Sbjct: 212 ELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKM 271
Query: 1415 LEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPK 1474
EQ++ + +++K L ++K+L E++K L ++ K+ E++++ EQ++ EQ++K E +
Sbjct: 272 REQEE-KMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQE 330
Query: 1475 DKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKH 1534
+K Q++R+ EQ++++ E++ K DQ+ R E +D K+ + + +K EQ+
Sbjct: 331 EKMWRQEERLWEQEKQMREQEQKMRDQEERMWE----QDERLREKEERMREQEKMWEQEE 386
Query: 1535 QAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPK 1594
+ QE+ +++ E++ + E+ E+ ++ EE Q QE+ QE+K + +
Sbjct: 387 KMQEE-ERIREREKKMREE------------EETMREQEEKMQKQEENMWEQEEKEWQQQ 433
Query: 1595 MLEEK-----SPEKVKAMEEKL----EALLEKTKALGLEESLVQEGRAREQEEKYWRGQD 1645
L E+ EK++ EEK+ E + ++ + G E+ + ++ + REQE++ W ++
Sbjct: 434 RLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEE 493
Query: 1646 VVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQDTYWRELSCERK 1705
+++ ++ +EE EQ E E+ EQ + W+ E + E+ T + E+K
Sbjct: 494 KMRDQEQKMWDQEERMWEQDERLREKEERMREQ-KKMWQQEEKMREEKKTQEQ----EKK 548
Query: 1706 VWFPHELDGQGAR-----PHYTEERESTFLDEGPDDEQEVPLREHATRSPWASDFKDFQE 1760
W E + R EE E E EQE +RE + W + K ++
Sbjct: 549 TWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM-WEQEEKMQEQ 607
Query: 1761 SSPQKGLEVERWLAESPVGLPPEEE 1785
E + W E + +EE
Sbjct: 608 EEKMWEQEEKMWEQEEEDKMQEQEE 632
Score = 102 bits (254), Expect = 5e-21
Identities = 84/321 (26%), Positives = 163/321 (50%), Gaps = 30/321 (9%)
Query: 1396 VKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDK 1455
+ NE +K+++ L++K R E + + ++ K L+ K E+ K L + + +++
Sbjct: 180 ITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRK----LERAKFLLPQVQTNTLQEE 235
Query: 1456 ALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTV 1515
Q++ EQ+ K + ++K Q++R+ EQ+ K+ E+++K Q+ R E ++
Sbjct: 236 MWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLRE----QEKE 291
Query: 1516 AEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEEN 1575
++++L + K EQ+ Q QEQ++K+ E++++ EQ E+ + EE
Sbjct: 292 LREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQ------------EEKMWRQEER 339
Query: 1576 HQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRARE 1635
QE++ QE K R EE+ E+ + + EK E + E+ K EE + +E R RE
Sbjct: 340 LWEQEKQMREQEQKMRDQ---EERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRE 396
Query: 1636 QEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTS-PEQDNRYWRGREDVALEQD 1694
+E+K ++ ++E +E +EE EQ+E W+ PEQ + W +E + +++
Sbjct: 397 REKKMREEEETMREQEEKMQKQEENMWEQEE--KEWQQQRLPEQKEKLWE-QEKMQEQEE 453
Query: 1695 TYWRELSCERKVWFPHELDGQ 1715
W + E K+ E+ GQ
Sbjct: 454 KIWEQ---EEKIRDQEEMWGQ 471
Score = 70.9 bits (172), Expect = 2e-11
Identities = 79/406 (19%), Positives = 194/406 (47%), Gaps = 20/406 (4%)
Query: 304 VPTN-LKPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKK 362
V TN L+ +Q + +E K K K+ ++EE + E + R E +++ + EK+
Sbjct: 227 VQTNTLQEEMWRQEEELREQEKKIRKQE-EKMWRQEERLREQEGKMR-EQEEKMRRQEKR 284
Query: 363 AKESSE--KPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEK 420
+E + + EK + ++ E E ++ ++ K+ + + + +EK+ + EE+ +++
Sbjct: 285 LREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 344
Query: 421 KEIKKERKELKKDEGR--KEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKA 478
K+++++ ++++ E R +++++ +KEE+ ++ + ++ K + E K + +
Sbjct: 345 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREE 404
Query: 479 KVPGRVKIDRSRA----IRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQD 534
+ R + ++ + + ++E + Q P QK + +E + E+ +D
Sbjct: 405 EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD 464
Query: 535 FEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKE 594
EEM +E+ + +++ + ++ + EE + Q+E + +++E
Sbjct: 465 QEEMWGQEKKMWRQEK---MREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEE 521
Query: 595 LVPEVPEEQGSKDRGLDSGAETEEEKDTW-EEKKQREAERLPDRTEAREESEPEVKEDVI 653
+ E + +++ + E+EK TW +E+K RE ER+ +R + E E ++E
Sbjct: 522 RMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE--- 578
Query: 654 EKAELEEMEEVHPSDEEE--EDATKAEGFYQKHMQEPLKVTPRSRE 697
++ +++E EE EE+ E K + +K ++ K+ + E
Sbjct: 579 QEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEE 624
Score = 63.9 bits (154), Expect = 2e-09
Identities = 89/442 (20%), Positives = 190/442 (42%), Gaps = 21/442 (4%)
Query: 333 KLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEK--PPEKPAKPERVKTESSEALKA 390
KL ++EE ++E +E E +++ + E+K E+ EK + + K E
Sbjct: 304 KLREQEEQMQE-QEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMW 362
Query: 391 EKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKR- 449
E+ + +++K + +EK+ + EEK +E++ ++E+K +++E +E+++ +K+E+
Sbjct: 363 EQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 422
Query: 450 -KDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVKI-DRSRAIRGEKELSSEPQTPPA 507
+ + E ++ P+ K E K + + KI ++ IR ++E+ + +
Sbjct: 423 WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE-----KIWEQEEKIRDQEEMWGQEKKMWR 477
Query: 508 QKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPF---PLDTA 564
Q+ +E + E D EE E+ L E+ + K
Sbjct: 478 QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMR 537
Query: 565 EEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAET--EEEKDT 622
EE + T + +EE + + ++ + E E ++ + E E+E+
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM 597
Query: 623 WE--EKKQREAERLPDRTEAREESEPEVKEDVIEKAELEEMEEVHPSDEEEEDATKAEGF 680
WE EK Q + E++ ++ E E E E K E+ E+ E++ +E+ + +
Sbjct: 598 WEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMRE 657
Query: 681 YQKHMQEPLKVTPRSREAFGGRELGLQGKAPE-KETSLFLSSLTTPAGATEHVSYIQDET 739
++ M+E + E +E +QG+ + +E + E + Q+E
Sbjct: 658 QEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEK 717
Query: 740 IPGYSETEQTISDEEIHDEPEE 761
+ G E + +E I D+ E+
Sbjct: 718 MWGQEEMRE--KEERIRDQKEK 737
Score = 61.6 bits (148), Expect = 1e-08
Identities = 84/382 (21%), Positives = 171/382 (44%), Gaps = 50/382 (13%)
Query: 312 KIKQRADSKESLKATTKTAVSKLAKREEVV----EEGAKEARSELAKELAKTEKKAKESS 367
+I++R + T + K+ K+EE + E+ ++ R KE ++K +E
Sbjct: 393 RIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQE 452
Query: 368 EK---PPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKK-DKEKKEI 423
EK EK E + + + + EK + +D++ ++ +EK+ E+K D+E++
Sbjct: 453 EKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ--EEKMRDQEQKMWDQEERMW 510
Query: 424 KKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGR 483
+++ + +K+E +E+KK ++EEK + E KK + + K + E K + R
Sbjct: 511 EQDERLREKEERMREQKKMWQQEEKMR----EEKKTQEQEKKTWDQEE-----KMREEER 561
Query: 484 VKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREER 543
++ +R + +R E+E+ E + +K + E + E + + E+M +E
Sbjct: 562 MR-EREKKMREEEEMMREQE----EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 616
Query: 544 ALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQ 603
+ ++ + + ++ + EE + + ++E M+E+E E EQ
Sbjct: 617 KMWEQEEEDKMQEQEEMMWEQEEKMQEQEEK--------MWEQEEKMREQE---EKMREQ 665
Query: 604 GSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAR----------EESEPEVKEDVI 653
K +G + +EEK +E+K RE E E + +E + +E++
Sbjct: 666 EEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMR 725
Query: 654 EKAEL-----EEMEEVHPSDEE 670
EK E E+M+E P EE
Sbjct: 726 EKEERIRDQKEKMQERLPEHEE 747
Score = 60.8 bits (146), Expect = 2e-08
Identities = 84/461 (18%), Positives = 210/461 (45%), Gaps = 25/461 (5%)
Query: 309 KPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSE-LAKELAKTEKKAKESS 367
K ++++++ ES K+ + V +L ++ E + + ++ L +E+ + E++ +E
Sbjct: 188 KNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQE 247
Query: 368 EKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKER 427
+K ++ K R E L+ ++ K+ +++ K +EK + +EK+ +E+++ +E+
Sbjct: 248 KKIRKQEEKMWR----QEERLREQEGKM-REQEEKMRRQEKRLREQEKELREQEKELREQ 302
Query: 428 KELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPD-LKPFTPEVRKTLYKAKVPGRVKI 486
K+L++ E + +E+++ E++ K + E K + + L ++R+ K +
Sbjct: 303 KKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMW 362
Query: 487 DRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALL 546
++ +R ++E E + Q+ + RE + E+ ++ EE +++ +
Sbjct: 363 EQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 422
Query: 547 AEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSK 606
EQ + + P + E+ +Q QEE + +++E + + E G +
Sbjct: 423 WEQEEKEWQQQRLP-EQKEKLWEQEKMQ---------EQEEKIWEQEEKIRDQEEMWGQE 472
Query: 607 DRGLDSGAETEEEKDTWE-EKKQREAER----LPDRTEAREESEPEVKEDVIEKAELEEM 661
+ E+E WE E+K R+ E+ +R ++E E +E + E+ ++ +
Sbjct: 473 KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQ 532
Query: 662 EEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFGGRELGLQGKAPEKETSLFLSS 721
EE +++ ++ K ++ M+E ++ R ++ E+ + + +E +
Sbjct: 533 EEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMRE 592
Query: 722 LTTPAGATEHVSYIQDETIPGYSETEQTISDEEIHDEPEER 762
E Q+E + E E+ + ++E D+ +E+
Sbjct: 593 QEEKMWEQEEKMQEQEEKM---WEQEEKMWEQEEEDKMQEQ 630
Score = 59.7 bits (143), Expect = 4e-08
Identities = 72/341 (21%), Positives = 153/341 (44%), Gaps = 40/341 (11%)
Query: 336 KREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKL 395
K + +EE KE R L+ EL + +E +K E K ++E SE
Sbjct: 156 KADRYIEELTKE-RDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEI-------- 206
Query: 396 IKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPE 455
++ K LK K+ + + + + +E +++E R++EKK K+EEK +
Sbjct: 207 ---QLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEER 263
Query: 456 LKKISKPDLKPFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLP 515
L++ + ++ ++R+ + + + ++ + +R +K+L + + Q+
Sbjct: 264 LRE-QEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQE------ 316
Query: 516 TISGHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQG 575
E + E + + E+M R+E L +++ + ++ + EE +
Sbjct: 317 ------EKMWEQEEKMREQEEKMWRQEERLWEQEKQ--MREQEQKMRDQEERMWEQDER- 367
Query: 576 TPPSVPGLGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTW---EEKKQREAE 632
L ++E M+E+E + E E+ ++R + + EE++T EEK Q++ E
Sbjct: 368 -------LREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 420
Query: 633 RL--PDRTEAREESEPEVKEDVIEKAELEEMEEVHPSDEEE 671
+ + E +++ PE KE + E+ +++E EE EE+
Sbjct: 421 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 461
Score = 43.9 bits (102), Expect = 0.002
Identities = 37/202 (18%), Positives = 95/202 (47%), Gaps = 9/202 (4%)
Query: 312 KIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEK-- 369
++++R + + K+ ++EE + E +E E +++ + E+K E EK
Sbjct: 561 RMREREKKMREEEEMMREQEEKMQEQEEKMRE-QEEKMWEQEEKMQEQEEKMWEQEEKMW 619
Query: 370 ---PPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKE 426
+K + E + E E ++ ++ K+ + + + +EK+ + EEK ++++++++
Sbjct: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQ 679
Query: 427 RKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVKI 486
++++ E + E+++ + ++ K E K + + E+R+ K + K
Sbjct: 680 EEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMRE---KEERIRDQKE 736
Query: 487 DRSRAIRGEKELSSEPQTPPAQ 508
+ +E SEP PP++
Sbjct: 737 KMQERLPEHEERCSEPCLPPSK 758
Score = 43.5 bits (101), Expect = 0.003
Identities = 28/157 (17%), Positives = 81/157 (51%), Gaps = 6/157 (3%)
Query: 309 KPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEG-----AKEARSELAKELAKTEKKA 363
+ K++++ D + + K+ +EE + E KE R K++ + E+K
Sbjct: 477 RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKM 536
Query: 364 KESSE-KPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKE 422
+E + + EK + K E ++ ++K+ +++ + +EK+ + EEK +++++
Sbjct: 537 REEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK 596
Query: 423 IKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKI 459
+ ++ +++++ E + E+++ E++ +D E +++
Sbjct: 597 MWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEM 633
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 140 bits (352), Expect = 2e-32
Identities = 432/2089 (20%), Positives = 728/2089 (34%), Gaps = 372/2089 (17%)
Query: 336 KREEVVEEGAKE-ARSELAKELAKTEKKAKESSE------KPPEK--PAKPERVKTESSE 386
+REE +EG +E + +E+ + +K+ E S K PEK P P+ +K E
Sbjct: 9128 EREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIE 9187
Query: 387 ALKAEKRKLIKDKVGKKHLKEKISKLEEKK------DKEKKEIKKERKELKKDEGRKEEK 440
++ R++ ++KV + E K+ +K +E E+K KK +E+
Sbjct: 9188 KIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKM 9247
Query: 441 KDAKK-EEKRKDTKPELKK-----------ISK--------PDL--KPFTPEVRKTLYKA 478
A EE+ T PE++K ISK P+L KP EV
Sbjct: 9248 FFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPK 9307
Query: 479 KV-PGRVKI----------DRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSS 527
KV P K+ ++ +KE ++ P+ P K VP I +
Sbjct: 9308 KVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEA 9367
Query: 528 PEDLTQDFEE-MKREERALLAEQRDTGLGD--------------KPFPLDTAEEGPPSTA 572
P + ++ + EE+ + QR+ KP P EE PP
Sbjct: 9368 PPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKE-EEVPP--- 9423
Query: 573 IQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWEEKKQREAE 632
PP VP L ++ V +EK VP ++ R S EEK E+K A
Sbjct: 9424 ----PPKVPALPKKP-VPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFA- 9477
Query: 633 RLPDRTEARE------------ESEPEVKEDVIEKAELEEMEEVHPSD----EEEEDATK 676
+P R E E E V V + E EE EE ++ EE E+
Sbjct: 9478 -VPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVV 9536
Query: 677 AEGFY---QKHMQEPLKVTPRSREAFGGRELGLQGKAPEKETSLFLSSLTTPAGATEHVS 733
E + ++ EP +VT R +++ L+ K P K PA E
Sbjct: 9537 EEKLHIISKRVEAEPAEVTERQE-----KKIVLKPKIPAKIEE------PPPAKVPEAPK 9585
Query: 734 YIQDET-IPGYSETEQTISDEEIHDEPE----ERPAPPRFHTSTYDLPGPEGAGPFEASQ 788
I E +P ++ + ++ +EP+ E+ PP+ LP + +Q
Sbjct: 9586 KIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQ 9645
Query: 789 PADSAVPATS------GKVYGTPETELTYPTNIVAAPLAEEEHVSSATSITECDKLSSFA 842
V T +V P+ + + P EEE + K++ F
Sbjct: 9646 EEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPA---------KVTEFR 9696
Query: 843 TSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEATQGLDYVPSAGTISPTSSLE 902
V +++ V S+ AP+ E + + E + A ++ E
Sbjct: 9697 KRVVKEEKV-SIEAPKREPQPIKEVTI---------MEEKERAYTLEEEAVSVQREEEYE 9746
Query: 903 EDKGFKSPPCEDFSVTGESEKRGEIIGKGLSGERAVEEEEEETANVEMSEKLCSQYGTPV 962
E + + E++ T E ++ E ER E EE + EK P
Sbjct: 9747 EYEEYDYKEFEEYEPTEEYDQYEEY------EEREYERYEEHEEYITEPEKPIPVKPVPE 9800
Query: 963 FSAPGHALHPGEPALGEAEERCLSPDDSTVKMASPPPSGPPSATHTPFHQSPVEEKSEPQ 1022
P P L +A P K+ PPP P EP+
Sbjct: 9801 EPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVP----------------EEPK 9844
Query: 1023 D-FQEADSWGDTKRTPGVGKEDAAEETVKP----GPEEGTLEKEEKVPPPRSPQA----Q 1073
F+E TKR E AA+ +KP E+ + ++E PP R P+ +
Sbjct: 9845 KVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELE 9904
Query: 1074 EAPVNIDEGLTGCTIQLLPAQDKAIVFEIME--AGEPTGPILGAEALPGGLRTLPQEPGK 1131
V +E + + L +++ + E E E P++ + + +P+E
Sbjct: 9905 PEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKP 9964
Query: 1132 ---PQKDEV--LRYPDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRW 1186
P+K E + P+ PE+ + + P A PK P + + +
Sbjct: 9965 VPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKK 10024
Query: 1187 PEVSPEDTQSLSLSEESPSKETSLDVSSKQLSPESLGTLQFGELNLGKEEMGHLMQAEDT 1246
E P + + P K+ + K +P + E+ + E+
Sbjct: 10025 VEAPPAKVPEVP-KKPVPEKKVPVPAPKKVEAPPAK-----------VPEVPKKLIPEEK 10072
Query: 1247 SHHTAPMSVPEPHAATASPPTDGTTRYSAQTDITDDSLDRKSPASSFSHSTPSGNGKYLP 1306
P P A PP R + +L ++ P
Sbjct: 10073 K------PTPVPKKVEAPPPKVPKKREPVPVPV---ALPQEEEVLFEEEIVPEEEVLPEE 10123
Query: 1307 GAITSPDEHILTPDSSFSKSPESLPGPALEDIAIKWEDKVPGLKDRTSEQKKEPEPKDEV 1366
+ +E +L + E +P P E++ + E+ VP ++ E++ PE K +V
Sbjct: 10124 EEVLPEEEEVLPEEEEVLPEEEEIP-PEEEEVPPE-EEYVPEEEEFVPEEEVLPEVKPKV 10181
Query: 1367 LQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALE--- 1423
E K+ V K I +K+EA K V + K +E+K L +++ L
Sbjct: 10182 -PVPAPVPEIKKKVTEKKVVIPKKEEAPPAK---VPEVPKKVEEKRIILPKEEEVLPVEV 10237
Query: 1424 QKDKALEP-KDKDLEEKDKALEQKD-----KIPEEKDKALEQKDTALEQKDKALEPKDKD 1477
++ EP ++++ E+ ++E+ + ++PE KA+ + T + +K +A K
Sbjct: 10238 TEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAK--- 10294
Query: 1478 LEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQ 1537
++ E+K +P +K +A KV V K PE V K + P +
Sbjct: 10295 --VSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVP-----PAKGRTVL 10347
Query: 1538 EQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQED--------- 1588
E+K V+ +++ ++++ + E +E ++ + E + E E +E
Sbjct: 10348 EEKVSVAFRQEVVVKERL-----ELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFI 10402
Query: 1589 KTRKPKMLEEKSPEKVKAMEEKLEA----LLEKTKALGLEESLVQEGRAREQEEKYWRGQ 1644
K + ++ EE EKV + E EA + EK KA + E EK +
Sbjct: 10403 KLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKA---------PPKGPEISEKIIPPK 10453
Query: 1645 DVVQEWQETSPTREEPAG--EQKELAPAWEDTSPEQDNRYWRGREDVALEQDTYWRELSC 1702
+ + P +E PA E + E ++ R + L +E+
Sbjct: 10454 ---KPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPP----KEVVP 10506
Query: 1703 ERKVWFPHELDGQGARPHYTEERESTFLDEG----PDDEQEVPLREHATRSPWASDFKDF 1758
E+KV P + P E + ++ P + EVP + A K
Sbjct: 10507 EKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKV 10566
Query: 1759 QESSPQKGLEVERWLAESPVGLPPEEED-------------KLTRSPFEIIS------PP 1799
E+ P K + E+P + PE++ K+ +P E++ PP
Sbjct: 10567 PEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPP 10626
Query: 1800 ASPPEMVGQRVPSAPGQESPIPDPKLMPHMKNEPTTP---------SWLADIPPWVPKDR 1850
PE+ +VP P + +P+ K+ + +P +P + PP +
Sbjct: 10627 PKKPEVPPTKVPEVP--KVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEE 10684
Query: 1851 PLPPAPLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPL--GKD 1908
P P AP P P PE PA + + + V E E+ PL K
Sbjct: 10685 PEPAAPPQVTVPPKKPVPEKKAPAVVA---KKPELPPVKVPEVPKEVVPEKKVPLVVPKK 10741
Query: 1909 YRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQYA 1968
+ E + P+K K PE + P++ E++ P P+
Sbjct: 10742 PEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPP 10801
Query: 1969 DIYEQMM-LTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQ 2027
++YE+ + P E P+ A + P E+ P P+ +
Sbjct: 10802 EVYEEPEEIAPEEEIAPEEEKPVPVAEEEEP-----------------EVPPPAVPEEPK 10844
Query: 2028 SDTPTFSYAALAGPTVPPRPEPGPSM---EPSLTP-PAVPPRAPILS------------- 2070
P + P PP EP P +P L P P PP AP
Sbjct: 10845 KIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIP 10904
Query: 2071 --KGPSPPLNGNILSCSP--------------DRRSPSPKESGRSHWDDSTSDSELEKGA 2114
K P P + +P R P PKE + L+
Sbjct: 10905 KKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKE-----------EVVLKSVL 10953
Query: 2115 REQPEKEAQS--------------PSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPS 2160
R++PE+E P PP P P+ + T+ P + + +P+
Sbjct: 10954 RKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPA 11013
Query: 2161 LDFPASAFGFSSLQPAPPQLPSPAEPRSAPCG---SLAFSGDRALALAP 2206
+ PA P P EP P ++ G +A A AP
Sbjct: 11014 IPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAP 11062
Score = 134 bits (337), Expect = 1e-30
Identities = 456/2256 (20%), Positives = 788/2256 (34%), Gaps = 301/2256 (13%)
Query: 305 PTNLKPSKIKQRAD---SKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEK 361
PT L P+K + D E +K T T ++ K +E V E + E + E+
Sbjct: 9016 PTTLIPAKAPEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFIESFEE 9075
Query: 362 KAKESSEKPPEKPAKPERVKT--ESSEALKAEKRKLIKDK------VGKKHLKEKISKLE 413
E +P +P + + E E +K E +K + ++ G+++ + + E
Sbjct: 9076 PYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDE 9135
Query: 414 EKKDKEKKEIKKERKELKKD--EGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEV 471
+++ E+ ++E +++K+ E E K AK EK+ P++ K KP ++
Sbjct: 9136 GEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIK------KPVIEKI 9189
Query: 472 RKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGH-RELVLS---- 526
KT + + +V++ + + +K + +P P Q+ + + + H +++V+S
Sbjct: 9190 EKTSRRME-EEKVQVTKVPEV-SKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKM 9247
Query: 527 -----SPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVP 581
+ E+++ E+++E + E+ + + P E P A + P VP
Sbjct: 9248 FFASHTEEEVSVTVPEVQKE--IVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAP-VP 9304
Query: 582 GLGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAR 641
+ E + VP+ P + K + K KK E++P A+
Sbjct: 9305 IPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPV-AK 9363
Query: 642 EESEPEVKEDVIEKAELEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFGG 701
++ P K ++K + E + + EE +K + E K PR E
Sbjct: 9364 KKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEE---- 9419
Query: 702 RELGLQGKAPEKETSLFLSSLTTPAGATEHVSYIQDETIPGYSETEQTISDEE--IHDEP 759
+ P K +L + A V + P +++T+ +E+ + +E
Sbjct: 9420 -----EVPPPPKVPALPKKPVPEEKVAVP-VPVAKKAPPPRAEVSKKTVVEEKRFVAEEK 9473
Query: 760 EERPAPPRFHTSTYDLPGPEGAGPFEASQPADSAVPATSGKVYGTPETELTYPTNIVAAP 819
P R + +++ E E + S VY E E +
Sbjct: 9474 LSFAVPQRVEVTRHEVSAEEEWSYSEEEE-------GVSISVYREEEREEEEEAEVTEYE 9526
Query: 820 LAE--EEHVSSATSITECDKLSSFATSVAEDQSVASLTAP----QTEETGKSSLLLDTVT 873
+ E EE+V ++ + V E Q + P + EE + +
Sbjct: 9527 VMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKK 9586
Query: 874 SIPSSRTEATQGLDYVPSAGTISPTSSLEEDKGFKSPPCEDFSVTGESEKRGEIIGKGLS 933
+P + A VP + P EE K P + V + K E + ++
Sbjct: 9587 IVPEKKVPAP-----VPKKEKVPPPKVPEEPK----KPVPEKKVPPKVIKMEEPLPAKVT 9637
Query: 934 GERAVEEEEEETANVEMSEKLCSQYGTPVFSAPGHALHPGEPALGEAEERCLSPDDSTVK 993
ER ++ +EE V +++K AP A P EP EE+ L
Sbjct: 9638 -ERHMQITQEEKVLVAVTKK----------EAPPKARVPEEPKRAVPEEKVLK------- 9679
Query: 994 MASPPPSGPPSATHTPFHQSPVEE--------KSEPQDFQEADSWGDTKRTPGVGKEDAA 1045
P P A T F + V+E K EPQ +E + +R + +E +
Sbjct: 9680 -LKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVS 9738
Query: 1046 ---EETVKPGPEEGTLEKEEKVPPPRSPQAQEAPVNIDEGLTGCTIQLLPAQDKAIVFEI 1102
EE + E E EE P Q +E E + + V +
Sbjct: 9739 VQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPV 9798
Query: 1103 MEAGEPTGPILGAEALPGGLRTLPQEPGKPQKDEVLRYPDRSLSPEDAESLSVLSVPSPD 1162
E PT P P K K V PE+ + VP P
Sbjct: 9799 PEEPVPTKP--------------KAPPAKVLKKAV---------PEEK-----VPVPIPK 9830
Query: 1163 TANQEPTPKSPCGLTEQYLHKDRWPEVSPEDTQSLSLSEESPSK------ETSLDVSSKQ 1216
+ P PK P + + K R E Q + + P K E + V K+
Sbjct: 9831 KL-KPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKE 9889
Query: 1217 LS-----PESLGTLQFGELNLGKEEMGH----LMQAEDTSHHTAPMSVPEPHAATASPPT 1267
++ PE L+ E+ +E + H L++ E+ H + E P
Sbjct: 9890 VAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIP-- 9947
Query: 1268 DGTTRYSAQTDITDDSLDRKSPASSFSHSTPSGNGKYLPGAIT-----SPDEH--ILTPD 1320
+ + RK P P K P A P+E +L P
Sbjct: 9948 -----------VKVPEVPRK-PVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPK 9995
Query: 1321 SSF---SKSPESLPGPALED-IAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLE- 1375
+K PE P E+ + + KV + E K+P P+ +V K +E
Sbjct: 9996 KEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEA 10055
Query: 1376 -HKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKAL----- 1429
+V E I ++ + V + K K R+ AL Q+++ L
Sbjct: 10056 PPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKV--PKKREPVPVPVALPQEEEVLFEEEI 10113
Query: 1430 EPKDKDLEEKDKAL-EQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQK 1488
P+++ L E+++ L E+++ +PEE++ E+++ E+++ + P+++ + +++ + ++
Sbjct: 10114 VPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEE--VPPEEEYVPEEEEFVPEE 10171
Query: 1489 EKIPEEKDKA-LDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKK 1547
E +PE K K + V ++ K E V K + K PE + E+K + K+
Sbjct: 10172 EVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPA-KVPEVPKKV-EEKRIILPKE 10229
Query: 1548 DQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAM 1607
++ L + +++ E+ I EE +E E + R P+++++ PE +
Sbjct: 10230 EEVLPVEVTEEPEEEPISEEEIP--EEPPSIEEVEEVA---PPRVPEVIKKAVPEAPTPV 10284
Query: 1608 EEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKEL 1667
+K+EA K EE + + +E P + E+K L
Sbjct: 10285 PKKVEAPPAKVSKKIPEEKVPVPVQKKEAP-------------PAKVPEVPKKVPEKKVL 10331
Query: 1668 APAWEDTSPEQDNRYWRGREDVALEQDTYWREL----SCERKVWFPHELDGQGARPHYTE 1723
P E P + + VA Q+ +E E +V E + Y E
Sbjct: 10332 VPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFE 10391
Query: 1724 ERESTFLDEGPDDEQEVPLREHATRSPW-------ASDFKDFQE-SSPQKGLEVERWL-- 1773
E E ++E EQ EH A + + F++ +P KG E+ +
Sbjct: 10392 EGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIP 10451
Query: 1774 -AESPVGLPPEEE--------------DKLTRSPFEIISPPASPPEMV-------GQRVP 1811
+ P + P +E ++ R P E PP PE++ ++VP
Sbjct: 10452 PKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVP 10511
Query: 1812 SAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSPAPGPPTP---AP 1868
P ++ P PK +P E P +PP PK +PP + P P P
Sbjct: 10512 VPPAKKPEAPPPK-VPEAPKE-VVPEKKVPVPP--PKKPEVPPTKVPEVPKAAVPEKKVP 10567
Query: 1869 ESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGEREEEGRAEAPDKS 1928
E+ P P S ++ V E P P + E +E + P
Sbjct: 10568 EAIPPKPESPPPEVPEAPKEVVPEKKVP-AAPPKKPEVTPVKVPEAPKEVVPEKKVP--- 10623
Query: 1929 SHSSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQYADIYEQMMLTGL--GPACPTR 1986
K PE + P+ PE++ P P + +++E+ L PA
Sbjct: 10624 VPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVE 10683
Query: 1987 EPPLGAAGD--WPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDTPTFSYAALAGPTVP 2044
EP A PP E A + + EL P+ + P + VP
Sbjct: 10684 EPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLV----VP 10739
Query: 2045 PRPEPGPSMEPSLTPPAVPPRAPILSKGPS-PPLNGNILSCSPDRRS----PSPKESGRS 2099
+PE P+ P + VP + + K P PP + P P P+ +
Sbjct: 10740 KKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERA--- 10796
Query: 2100 HWDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARP 2159
+S E+ PE+E +P P+P+ E E V PP P P
Sbjct: 10797 ---ESPPPEVYEEPEEIAPEEEI-APEEEKPVPVAE-----EEEPEVPPP----AVPEEP 10843
Query: 2160 SLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLE 2219
P APP P EP R P PP ++ +
Sbjct: 10844 KKIIPEKKVPVIKKPEAPP----PKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQ 10899
Query: 2220 VTKAPSLD-SSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFSPS 2278
+ P PQ+P + + L E V+ SV R P
Sbjct: 10900 LKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVL-RKRPE 10958
Query: 2279 LEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLE 2338
E + E +L+ +PA P PP + P++ P +
Sbjct: 10959 EEEPKVEPKKLEKVKKPAV----------PEPPPPKPVEEVEVPTVTKRERKIPEPTKVP 11008
Query: 2339 CSEAATEKPSPFQVPSEDCAAN----GPTETSPNP-PGPAPAKAENEEAAACPAWERGAW 2393
+ A P+P P + P E P P P ++A A E A
Sbjct: 11009 EIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAK 11068
Query: 2394 PEGAER---SSRPDTLLSPEQPVCPAGGSGGPPSSA 2426
P+G + P + + + + P G PP A
Sbjct: 11069 PKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEA 11104
Score = 132 bits (331), Expect = 6e-30
Identities = 465/2218 (20%), Positives = 793/2218 (35%), Gaps = 374/2218 (16%)
Query: 347 EARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLK 406
EARS EL T K+ K KPP+ P + T A+ E+ V +
Sbjct: 8914 EARS--TAELYLTTKEIKLEL-KPPDIPDSRVPIPTMPIRAVPPEEIP----PVVAPPIP 8966
Query: 407 EKISKLEEKKDKEKK-EIKKERKELKKDEGRKEEKKDAKKE-EKRKDTKPELKKISKPDL 464
+ EEKK K+ E+ K K KKDAKK K K+ P + + KP
Sbjct: 8967 LLLPTPEEKKPPPKRIEVTK-----------KAVKKDAKKVVAKPKEMTPREEIVKKPP- 9014
Query: 465 KPFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELV 524
P T TL AK P + ++SS+ + V + TI+ +E V
Sbjct: 9015 -PPT-----TLIPAKAPEII------------DVSSKAEE-------VKIMTITRKKE-V 9048
Query: 525 LSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLG 584
E + + + + +E+R + + P D E P + + P
Sbjct: 9049 QKEKEAVYEKKQAVHKEKRVFIESFEE--------PYDELEVEPYTEPFEQPYYEEPDED 9100
Query: 585 QEEHVMKEKELVPEVPEE---QGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAR 641
EE ++ K+ V E EE +G + + G + EE+ WEE Q E E + + E
Sbjct: 9101 YEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEE--WEEAYQ-EREVIQVQKEVY 9157
Query: 642 EESE--------PEVKED----VIEKAELEEMEEVHPSDEEEE-DATKAEGFYQKHMQEP 688
EES PE K VI+K +E++E+ EEE+ TK +K + +
Sbjct: 9158 EESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQK 9217
Query: 689 LKVTPRSREAFGGRELGLQGKAPE-KETSLFLSSLTTPAGATEHVSYIQDETIPGYSETE 747
TP E + + K E +F +S T E VS T+P +
Sbjct: 9218 PSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTE-----EEVSV----TVPEVQK-- 9266
Query: 748 QTISDEEIHDEPEERPAPPRFHTSTYDLPGPEGAGPFEASQPADSAVPAT---------- 797
+ +++E+IH +R PP + P PE P + + P
Sbjct: 9267 EIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPE 9326
Query: 798 SGKVYGTPETELTYPTNIVAAP---LAEEEHVSSATSITECD--KLSSFATSVAEDQSVA 852
K P+ E P + P + EE+ E K+ V ++ +
Sbjct: 9327 EKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKIT 9386
Query: 853 SLTAPQTEETGKSSLLLDTVTSIPSSRTEATQGLDYVPSAGTIS--PTSSLEEDK----- 905
+T Q EE+ ++ +P R + + VP + P + E+K
Sbjct: 9387 IVT--QREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPV 9444
Query: 906 --GFKSPP--CEDFSVTGESEKRGEIIGK-GLSGERAVEEEEEETANVEMSEKLCSQYGT 960
K+PP E T EKR K + + VE E + E + G
Sbjct: 9445 PVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGV 9504
Query: 961 PVFSAPGHALHPGEPALGEAEERCLSPDDSTVK----MASPPPSGPPSATHTPFHQSPVE 1016
+ E A E P++ V+ + S P+ + V
Sbjct: 9505 SISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVL 9564
Query: 1017 EKSEPQDFQEADSWGDTKRTPGVGKEDAAEETVKPGPEEGTLEKEEKVPPPRSPQAQEAP 1076
+ P +E + P K+ E+ V P P + K+EKVPPP+ P+ + P
Sbjct: 9565 KPKIPAKIEEPPP----AKVPEAPKKIVPEKKV-PAP----VPKKEKVPPPKVPEEPKKP 9615
Query: 1077 VNIDEGLTGCTIQL---LPAQDKAIVFEIMEAGEPTGPILGAEALPGGLRTLPQEPGK-- 1131
V ++ + I++ LPA+ +I + + + EA P +P+EP +
Sbjct: 9616 VP-EKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKA--RVPEEPKRAV 9672
Query: 1132 PQKDEVLRYPDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRWPEVSP 1191
P++ + P R P + V + + E + P + E + +++ +
Sbjct: 9673 PEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTL 9732
Query: 1192 EDTQSLSLSEESPSKETSLDVSSKQLSPESLGTLQFGELNLGKEEMGHLMQAEDTSHHTA 1251
E+ +++S+ E +E + K+ E T ++ + +E + E H
Sbjct: 9733 EE-EAVSVQREEEYEEYE-EYDYKEFE-EYEPTEEYDQYEEYEER-----EYERYEEHEE 9784
Query: 1252 PMSVPEPHAATASPPTDGTTRYSAQTDITDDSLDRKSPASSFSHSTPSGNGKYLPGAITS 1311
++ PE P + P + + P+ K L A+
Sbjct: 9785 YITEPEKPIPVKPVPEE--------------------PVPTKPKAPPA---KVLKKAV-- 9819
Query: 1312 PDEHILTPDSSFSKSPESLPGPALEDIAIKWEDKVP-GLKDRTSEQKKEPEPKDEVLQQK 1370
P+E + P K P P E+ +E+K+ + R EQ EP K
Sbjct: 9820 PEEKVPVPIPKKLKPP---PPKVPEEPKKVFEEKIRISITKREKEQVTEPAAK------- 9869
Query: 1371 DKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQK------DTALEQ 1424
++ K VV + + +K+ A V+ V + K LE + E++ + +E+
Sbjct: 9870 -VPMKPKRVVAEEKVPVPRKEVAPPVR---VPEVPKELEPEEVAFEEEVVTHVEEYLVEE 9925
Query: 1425 KDKALEPKDKDLEEKDKALEQKDKIPEEKDKAL--EQKDTALEQKDKALEPKDKDLEQKD 1482
+++ + +++ + E++ K+PE K + E+K + +K +A K ++ +K
Sbjct: 9926 EEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKP 9985
Query: 1483 RVLEQKEKIP---EEKDKALDQKVRSVEHK-APEDTVAEMKDRDLEQTDKAPEQKHQAQE 1538
+EK+P +K+K KV V K PE+ V + +E AP K +
Sbjct: 9986 -----EEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVE----APPAK-VPEV 10035
Query: 1539 QKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDK--TRKPKML 1596
K V EKK K K EA + + + L+ E+K T PK +
Sbjct: 10036 PKKPVPEKKVPVPAPK------KVEAPPAKVPEVPKK--------LIPEEKKPTPVPKKV 10081
Query: 1597 EEKSPEKVKAMEE-KLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSP 1655
E P+ K E + L + + + EE +V E +EE +V+ E +E P
Sbjct: 10082 EAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEE------EVLPEEEEVLP 10135
Query: 1656 TREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQDTY---------------WREL 1700
EE E++E+ P E+ PE++ Y E+ E++ ++
Sbjct: 10136 EEEEVLPEEEEIPPEEEEVPPEEE--YVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKK 10193
Query: 1701 SCERKVWFPHELDGQGAR----PHYTEERESTFLDEGPDDEQEVPLREHATRSPWASDFK 1756
E+KV P + + A+ P EE+ P +E+ +P+ T P
Sbjct: 10194 VTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIIL----PKEEEVLPV--EVTEEPEEEPIS 10247
Query: 1757 DFQESSPQKGLEVERWLAESPVGLPPEEEDKLTRSPFEIISPPASPPEMVGQRVPSAPGQ 1816
+E P++ +E +P +P + + +P + +PP V +++P +
Sbjct: 10248 --EEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPE---E 10302
Query: 1817 ESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSPAPGPPTPAPESHTPAPF 1876
+ P+P ++ + P+ + ++P VP+ + L P + P E F
Sbjct: 10303 KVPVP-------VQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAF 10355
Query: 1877 SWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPE 1936
+ + V E AE+E P E EE E + +V E
Sbjct: 10356 RQEVVVKERLELEVVE--AEVEEIP-------------EEEEFHEVEEYFEEGEFHEVEE 10400
Query: 1937 ASK--SHATTEPEQTEPEQREPTPYPDERSFQYADIYEQMMLTGLGP-----ACPTREPP 1989
K H E + E R + E +++E+ GP P ++PP
Sbjct: 10401 FIKLEQHRVEEEHRVEKVHRVIEVFEAEE----VEVFEKPKAPPKGPEISEKIIPPKKPP 10456
Query: 1990 LGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDTPTFSYAALAGPTVPPR--- 2046
P E + E+++ P P+ + P +PP+
Sbjct: 10457 TKVVPRKEPPAKVPEVP--KKIVVEEKVRVPEEPRVPPTKVP---------EVLPPKEVV 10505
Query: 2047 PEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDSTS 2106
PE + P+ P A PP+ P K P+++ P P + T
Sbjct: 10506 PEKKVPVPPAKKPEAPPPKVPEAPK-----------EVVPEKKVPVPPP--KKPEVPPTK 10552
Query: 2107 DSELEKGA---REQPEKEAQSP-SPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLD 2162
E+ K A ++ PE P SPP +P + PE + +PP + P + +
Sbjct: 10553 VPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVP-E 10611
Query: 2163 FPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEVTK 2222
P + PP+ P + +A + P P + + E
Sbjct: 10612 APKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEE--- 10668
Query: 2223 APSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFSPSLEAA 2282
P+ + P A ++ P PA+P + T P V E+ +P++ A
Sbjct: 10669 --------PEEVALEEPPAEVVEE-PEPAAP-------PQVTVPPKKPVPEKKAPAVVA- 10711
Query: 2283 EQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLECSEA 2342
+ EL P P P P + L + P P A
Sbjct: 10712 --KKPELPPVKVPE-------VPKEVVPEKKVPLVVPKKPEAP---------------PA 10747
Query: 2343 ATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAACPAWERGAWPEGAERSSR 2402
+ VP + A E P P K EE A P ER P E
Sbjct: 10748 KVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPP-PEVYEE 10806
Query: 2403 PDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELS-PSFLNPPLPP 2459
P+ ++PE+ + P P + E E P EP+ E P P PP
Sbjct: 10807 PEE-IAPEEEIAPE-EEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPP 10862
Score = 93.6 bits (231), Expect = 2e-18
Identities = 293/1330 (22%), Positives = 466/1330 (35%), Gaps = 246/1330 (18%)
Query: 304 VPTNLKPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAK-----------EARSEL 352
+P LKP K + K+ + + +++K K E+V E AK E
Sbjct: 9828 IPKKLKPPPPKVPEEPKKVFEEKIRISITKREK-EQVTEPAAKVPMKPKRVVAEEKVPVP 9886
Query: 353 AKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDK------------- 399
KE+A + + E PE+ A E V T E L E+ + I ++
Sbjct: 9887 RKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVI 9946
Query: 400 ------VGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEG------RKEEKKDAKKEE 447
V +K + E+ + K KE K K +E +KE+ AK E
Sbjct: 9947 PVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPE 10006
Query: 448 KRKDTKPELK-------KISKPDLKPFTPEV-RKTLYKAKVP----GRVKIDRSRAIRGE 495
K PE K K+ P K PEV +K + + KVP +V+ ++
Sbjct: 10007 VPKKPVPEEKVPVPVPKKVEAPPAK--VPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVP 10064
Query: 496 KELSSEPQ--TPPAQKGTVPLPTISGHRELV---LSSPEDLTQDFEEMKREERALLAEQR 550
K+L E + TP +K P P + RE V ++ P++ FEE E +L E+
Sbjct: 10065 KKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEE 10124
Query: 551 DTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKDRGL 610
+ P L +EE V+ E+E +P PE
Sbjct: 10125 EV-----------------------LPEEEEVLPEEEEVLPEEEEIP--PE--------- 10150
Query: 611 DSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIEKAELEEMEEVHPSDEE 670
EEE EE E E +P+ EE PEVK V A + E+
Sbjct: 10151 ------EEEVPPEEEYVPEEEEFVPE-----EEVLPEVKPKVPVPAPVPEI--------- 10190
Query: 671 EEDATKAEGFYQKHMQEPLKVTPRSREAFGGRELGLQGKAPEKETSLFLSSLTTPAGATE 730
+K + E V P+ EA + + K EK L P TE
Sbjct: 10191 -----------KKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTE 10239
Query: 731 HVSYIQDETIPGYSETEQTISDEEIHDEPE-----ERPAPPRFHTSTYDLPGPEGAGPFE 785
E+ IS+EEI +EP E APPR +P E
Sbjct: 10240 -------------EPEEEPISEEEIPEEPPSIEEVEEVAPPR-------VPEVIKKAVPE 10279
Query: 786 ASQPADSAVPATSGKV-YGTPETELTYPTNIVAAPLAEEEHVSSATSITECDKLSSFATS 844
A P V A KV PE ++ P AP A+ V + A
Sbjct: 10280 APTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVP 10339
Query: 845 VAEDQSVAS---LTAPQTEETGKSSLLLDTVTSIPSSRTEATQGLDYVPSAGTISPTSSL 901
A+ ++V A + E K L L+ V + ++ +P
Sbjct: 10340 PAKGRTVLEEKVSVAFRQEVVVKERLELEVVEA----------EVEEIPEEEEFHEVEEY 10389
Query: 902 EEDKGFKSPPCEDF----SVTGESEKRGEIIGKGLSGERAVEEEEEETANV-----EMSE 952
E+ F E+F E E R E + + + A E E E E+SE
Sbjct: 10390 FEEGEFHE--VEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISE 10447
Query: 953 KLCSQYGTPVFSAPGH---ALHPGEPALGEAEERCLSPDDSTVKMASPPPSGPPSATHTP 1009
K+ P P A P P EE+ P++ V P PP P
Sbjct: 10448 KIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEV-VP 10506
Query: 1010 FHQSPVEEKSEPQDFQEADSWGDTKRTPGVGKEDAAEETVKPGPEEGTLEKEEKVPPPRS 1069
+ PV +P+ + P KE E+ V P K+ +VPP +
Sbjct: 10507 EKKVPVPPAKKPE--------APPPKVPEAPKEVVPEKKVPVPP-----PKKPEVPPTKV 10553
Query: 1070 PQAQEAPV---NIDEGLTGCTIQLLPAQDKAIVFEIMEAGEPTGPILGAEALPGGLRTLP 1126
P+ +A V + E + P +A + E P P E P + P
Sbjct: 10554 PEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAP 10613
Query: 1127 QEPGKPQKDEVLRYPDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRW 1186
+E +K V + P + ++VP P PK E + +
Sbjct: 10614 KEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIP-PKPESPPPEVFEEPE-- 10670
Query: 1187 PEVSPEDTQSLSLSEESPSKETSLDVSSKQLSPESLGTLQFGELNLGKEEMGHL----MQ 1242
EV+ E+ + + E P+ + V K+ PE + K E+ + +
Sbjct: 10671 -EVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAK----KPELPPVKVPEVP 10725
Query: 1243 AEDTSHHTAPMSVP-EPHAATASPPTDGTTRYSAQTDITDDSLDRKSPASSFSHSTPSGN 1301
E P+ VP +P A A P ++ + + K A P
Sbjct: 10726 KEVVPEKKVPLVVPKKPEAPPAKVP-----------EVPKEVVPEKKVAVPKKPEVPPAK 10774
Query: 1302 GKYLP-GAITSPDEHILTPDSSFSKSPESLPGPALEDIAIKWEDKVPGLKDRTSEQKKEP 1360
+P + + P+ + S PE P E+IA + E K +++EP
Sbjct: 10775 VPEVPKKPVLEEKPAVPVPERAESPPPEVYEEP--EEIAPEEEIAPEEEKPVPVAEEEEP 10832
Query: 1361 EPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDT 1420
E + + E K+++ K + +K EA K + +K +E+ L+ +
Sbjct: 10833 EVPPPAVPE-----EPKKIIPEKKVPVIKKPEAPPPKE---PEPEKVIEKP--KLKPRPP 10882
Query: 1421 ALEQKDKALEPKDKDLEEK---DKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKD 1477
+ K+K + K K + +K ++P EK + K E+K + L P+ K
Sbjct: 10883 PPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVP-EKVELTPLKVPGGEKKVRKLLPERKP 10941
Query: 1478 LEQKDRVLEQ--KEKIPEEKDKALDQKVRSVEHKA-----PEDTVAEM-------KDRDL 1523
+++ VL+ +++ EE+ K +K+ V+ A P V E+ ++R +
Sbjct: 10942 EPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKI 11001
Query: 1524 EQTDKAPEQK 1533
+ K PE K
Sbjct: 11002 PEPTKVPEIK 11011
Score = 91.3 bits (225), Expect = 1e-17
Identities = 361/1742 (20%), Positives = 607/1742 (34%), Gaps = 311/1742 (17%)
Query: 309 KPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKEL---AKTEKKAKE 365
+P+++ +R + K LK AK EE EA ++ E A KK K
Sbjct: 9550 EPAEVTERQEKKIVLKPKIP------AKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKV 9603
Query: 366 SSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLK----EKISKLEEKKD---- 417
K PE+P KP K + +K E+ + KV ++H++ EK+ KK+
Sbjct: 9604 PPPKVPEEPKKPVPEKKVPPKVIKMEEP--LPAKVTERHMQITQEEKVLVAVTKKEAPPK 9661
Query: 418 ----KEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRK 473
+E K E K LK R+EE E +++ K E I P +P P
Sbjct: 9662 ARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREP-QPIKEV 9720
Query: 474 TLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQ 533
T+ + K + + +++ E+E + ++E P +
Sbjct: 9721 TIMEEKERAYTLEEEAVSVQREEEYEEYEEYD--------------YKEFEEYEPTEEYD 9766
Query: 534 DFEEMKREERALLAEQRD-TGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVM-- 590
+EE + E E + +KP P+ E P T + P V E +
Sbjct: 9767 QYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPV 9826
Query: 591 ----KEKELVPEVPEE--------------QGSKDRGLDSGAETE--------EEKDTWE 624
K K P+VPEE + K++ + A+ EEK
Sbjct: 9827 PIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVP 9886
Query: 625 EKKQREAERLPDRTEAREESEPEVKEDVIEKAEL----EEMEEVHPSDE---EEEDA--- 674
K+ R+P+ + E E +E+V+ E EE E +H +E EEE
Sbjct: 9887 RKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVI 9946
Query: 675 -TKAEGFYQKHMQEPLKVTP--RSREAFGGRELGLQGKAPEKETSLFLSSLTTPAGATEH 731
K +K + E K P + +EA + + K EK L P
Sbjct: 9947 PVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPE 10006
Query: 732 VSY--IQDETIPGYSETEQTISDEEIHDEPEER--------PAPPRFHTSTYDLPG-PEG 780
V + +E +P + ++ + P++ PAP + +P P+
Sbjct: 10007 VPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKK 10066
Query: 781 AGPFEASQ-PADSAVPATSGKVYGTPETELTYPTNIVAAPLAEEEHVSSATSITECDKLS 839
P E P V A KV E P + A EEE + + E + L
Sbjct: 10067 LIPEEKKPTPVPKKVEAPPPKVPKKRE-----PVPVPVALPQEEEVLFEEEIVPEEEVLP 10121
Query: 840 SFATSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEATQGLDYVPSAGTISPTS 899
+ E++ V P+ EE +L IP E +YVP P
Sbjct: 10122 EEEEVLPEEEEVL----PEEEE------VLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEE 10171
Query: 900 SLEEDKGFKSP---PCEDFSVTGESEKRGEIIGKGLSGERAVEEEEEETANVEMSEKLCS 956
+ + K P P + I K ++ ++ V ++EE ++
Sbjct: 10172 EVLPEVKPKVPVPAPVPE-------------IKKKVTEKKVVIPKKEEAPPAKV------ 10212
Query: 957 QYGTPVFSAPGHALHPGEPALGEAEERCLSPDDSTVKMASPPPSGPPSATHTPFHQSPVE 1016
P P E E+R + P + V PVE
Sbjct: 10213 ---------------PEVPKKVE-EKRIILPKEEEVL--------------------PVE 10236
Query: 1017 EKSEPQDFQEADSWGDTKRTPGVGKEDAAEETVKPGPEEGTLEKEEKVPPPRSPQA---- 1072
EP++ E +EE + P ++E+ E+V PPR P+
Sbjct: 10237 VTEEPEE------------------EPISEEEIPEEPP--SIEEVEEVAPPRVPEVIKKA 10276
Query: 1073 -QEAPVNIDEGLTGCTIQLLPAQDKAIVFEIMEAGEPTGPILGAEALPGGLRTLPQEPGK 1131
EAP + + ++ PA+ + +I E P P+ EA P +P+ P K
Sbjct: 10277 VPEAPTPVPK-----KVEAPPAK---VSKKIPEEKVPV-PVQKKEAPPA---KVPEVPKK 10324
Query: 1132 PQKDEVLRYPDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRWPEVSP 1191
+ +VL ++ P A+ +VL QE K L EV
Sbjct: 10325 VPEKKVLVPKKEAVPP--AKGRTVLEEKVSVAFRQEVVVKERLEL-----------EVVE 10371
Query: 1192 EDTQSLSLSEESPSKETSLDVSSKQLSPESLGTLQFGELNLGKEEMGHLMQAEDTSHHTA 1251
+ EE P +E +V E +F +L + E H ++
Sbjct: 10372 AEV------EEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVF 10425
Query: 1252 PMSVPEPHAATASPPTDGTTRYSAQTDITDDSLD-RKSPASSFSHSTPSGNGKYLPGAIT 1310
E +PP +I++ + +K P P +P I
Sbjct: 10426 EAEEVEVFEKPKAPPKG--------PEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIV 10477
Query: 1311 SPDEHILTPDSSF---SKSPESLPGPALEDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVL 1367
+E + P+ +K PE LP +++ + + VP K + K PE EV+
Sbjct: 10478 V-EEKVRVPEEPRVPPTKVPEVLPP---KEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVV 10533
Query: 1368 QQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQ--KDTALEQK 1425
+K + + E T + + +A + + + E ++ + K+ E+K
Sbjct: 10534 PEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKK 10593
Query: 1426 DKALEPKDKDLE-----EKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQ 1480
A PK ++ E K + + K+P K E T + + K P+ K
Sbjct: 10594 VPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKK---- 10649
Query: 1481 KDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQK 1540
E IP + + + E A E+ AE+ + E AP Q K
Sbjct: 10650 ------VPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVE---EPEPAAPPQV--TVPPK 10698
Query: 1541 DKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDK-----TRKPKM 1595
V EKK A+ K K E + + + +++ LV K + P++
Sbjct: 10699 KPVPEKKAPAVVAK------KPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEV 10752
Query: 1596 LEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSP 1655
+E PEK A+ +K E K + + L ++ E +V +E +E +P
Sbjct: 10753 PKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAP 10812
Query: 1656 TREEPAGEQKELAPAWEDTS-------PEQDNRYWRGREDVALEQDTY------WRELSC 1702
E E+K + A E+ PE+ + ++ +++ E
Sbjct: 10813 EEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVI 10872
Query: 1703 ERKVWFPHELDGQGARPHYTEERESTFLDEGPD----DEQEVPLREHATRSPWASDFKDF 1758
E+ P A P + + L P ++ +VP + T K
Sbjct: 10873 EKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKV 10932
Query: 1759 QESSPQKGLEVERWLAESPV--GLPPEEEDKLTRSPFEIISPPA----SPPEMVGQ-RVP 1811
++ P++ E + + V P EEE K+ E + PA PP+ V + VP
Sbjct: 10933 RKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVP 10992
Query: 1812 SAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSPAPGPPTPAPESH 1871
+ +E IP+P +P +K IP P+ +P P A + PP +
Sbjct: 10993 TVTKRERKIPEPTKVPEIK---------PAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTP 11043
Query: 1872 TPAPFSWGTAEYDSVVAAVQEGAAE----LEGGPY---SPLGKDYRKAE-GEREEEGRAE 1923
AP + + A +E AA+ ++G P SP+ + RK G E+ E
Sbjct: 11044 IAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPDE 11103
Query: 1924 AP 1925
AP
Sbjct: 11104 AP 11105
Score = 68.2 bits (165), Expect = 1e-10
Identities = 263/1230 (21%), Positives = 432/1230 (35%), Gaps = 238/1230 (19%)
Query: 236 EAEISVPYLTSITALVVWLPANPTEKIVRVLFPGNAPQN------KILEGLEKLRHLDFL 289
E ++ VP + A +P P + + P AP+ K+ E +KL +
Sbjct: 10014 EEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKK 10073
Query: 290 RYPVATQKDLASGAVPTNLKPSKIKQRADSKESLKATTKTAVSK--LAKREEVVEEGAKE 347
PV + + VP +P + +E + + + L + EEV+ E +E
Sbjct: 10074 PTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPE-EEE 10132
Query: 348 ARSELAKELAKTEKKAKESSEKPPEKPAKPERVK-TESSEALKAEKRKL--------IKD 398
E + L + E+ E E PPE+ PE + E L K K+ IK
Sbjct: 10133 VLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKK 10192
Query: 399 KVGKKHLKEKISKLEE----------KKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEK 448
KV +K K I K EE KK +EK+ I + +E+ E +E +++ EE+
Sbjct: 10193 KVTEK--KVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEE 10250
Query: 449 RKDTKPELKKISKPDLKPFTPEV-RKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPA 507
+ P ++++ + P PEV +K + +A P K++ A + K++ E P
Sbjct: 10251 IPEEPPSIEEVEEV-APPRVPEVIKKAVPEAPTPVPKKVEAPPA-KVSKKIPEEKVPVPV 10308
Query: 508 QKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEG 567
QK P + PE K E+ +L ++ E
Sbjct: 10309 QKKEAPPAKV----------PE------VPKKVPEKKVLVPKK--------------EAV 10338
Query: 568 PPSTAIQGTPPSVPGLGQEEHVMKEK-EL------VPEVPEEQGSKDRGLDSGAETEEEK 620
PP+ V ++E V+KE+ EL V E+PEE+ E E +
Sbjct: 10339 PPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEE-----------EFHEVE 10387
Query: 621 DTWEEKKQREAERLPDRTEAREESEPEVKE--DVIEKAELEEMEEVHPSDEEEEDATKAE 678
+ +EE + E E + R E E V++ VIE E EE+E E+ + K
Sbjct: 10388 EYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVF----EKPKAPPKGP 10443
Query: 679 GFYQKHM---QEPLKVTPRSREAFGGRELGLQGKAPEKETSLFLSSLTTPAGATEHVSYI 735
+K + + P KV PR K PE + + E V
Sbjct: 10444 EISEKIIPPKKPPTKVVPRKEP---------PAKVPEVPKKIVVE---------EKVRVP 10485
Query: 736 QDETIPGYSETEQTISDEEIHDEPEERPAPPRFHTSTYDLPGPEGAGPFEASQPADSAVP 795
++ +P ++ + + +E+ E ++ P PP PE P P + VP
Sbjct: 10486 EEPRVPP-TKVPEVLPPKEVVPE-KKVPVPP--------AKKPEAPPPKVPEAPKE-VVP 10534
Query: 796 ATSGKVYGTPETELTYPTNIVAAPLA--EEEHVSSATSITECDKLSSFATSVAEDQSVAS 853
V + E+ PT + P A E+ V A
Sbjct: 10535 EKKVPVPPPKKPEVP-PTKVPEVPKAAVPEKKVPEAI------------------PPKPE 10575
Query: 854 LTAPQTEETGKSSLLLDTVTSIPSSRTEATQGLDYVPSAGTISPTSSLEEDKGFKSPPCE 913
P+ E K + V + P + E T P +P + E K PP
Sbjct: 10576 SPPPEVPEAPKEVVPEKKVPAAPPKKPEVT------PVKVPEAPKEVVPEKKVPVPPP-- 10627
Query: 914 DFSVTGESEKRGEIIGKGLSGERAVEEEEEETANVEMSEKLCSQYGTPVFSAPGHALHPG 973
K+ E+ + E V + EK + + P P
Sbjct: 10628 ---------KKPEV----------PPTKVPEVPKVAVPEKKVPE------AIPPKPESPP 10662
Query: 974 EPALGEAEERCLSPDDSTVKMASPPPSGPPSATHTPFHQSPVEEKSEPQDFQEADSWGDT 1033
E EE L + V + P P+ PP T P + PV EK P +
Sbjct: 10663 PEVFEEPEEVALEEPPAEV-VEEPEPAAPPQVTVPP--KKPVPEKKAPAVVAKKPELPPV 10719
Query: 1034 KRTPGVGKEDAAEETVKPGPEEGTLEKEEKVPPPRSPQAQEAPVNIDEGLTGCTIQLLPA 1093
K P V KE E+ V + K+ + PP + P+ + V + ++ PA
Sbjct: 10720 K-VPEVPKEVVPEKKVPL-----VVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPA 10773
Query: 1094 QDKAIVFEIMEAGEPTGPI-LGAEALPGGLRTLPQEPGKPQKDEVLRYPDRSLSPEDAES 1152
+ + + + +P P+ AE+ P + P+E P+ ++PE+ +
Sbjct: 10774 KVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIA----------PEEEIAPEEEKP 10823
Query: 1153 LSVLSVPSPD----TANQEPTPKSPCGLTEQYLHKDRWPEVSPEDTQSLSLSEESPSKET 1208
+ V P+ +EP P + P PE + + + P
Sbjct: 10824 VPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPP 10883
Query: 1209 SLDVSSKQLSPESLGTLQFGELNLGKEEMGHLMQAEDTSHHTAPMSVP--EPHAATASPP 1266
K+ E + L+ + K+++ Q + T P+ VP E P
Sbjct: 10884 PPPAPPKEDVKEKIFQLK----AIPKKKVPEKPQVPEKVELT-PLKVPGGEKKVRKLLP- 10937
Query: 1267 TDGTTRYSAQTDITDDSLDRKSPASSFSHSTPSGNGKYLPGAITSPD-----EHILTPDS 1321
+ + ++ S+ RK P P K A+ P E + P
Sbjct: 10938 ---ERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVP-- 10992
Query: 1322 SFSKSPESLPGPALEDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVE 1381
+ +K +P P KVP +K EP+PK E + KT++ VE
Sbjct: 10993 TVTKRERKIPEPT----------KVPEIKPAIPLPAPEPKPKPEA---EVKTIK-PPPVE 11038
Query: 1382 PKDTAIY---------QKDEALHVKNEAVK 1402
P+ T I +K EA K EA K
Sbjct: 11039 PEPTPIAAPVTVPVVGKKAEAKAPKEEAAK 11068
Score = 57.8 bits (138), Expect = 2e-07
Identities = 118/527 (22%), Positives = 203/527 (38%), Gaps = 74/527 (14%)
Query: 355 ELAKTEKKAKESSEKPPEKPA-----KPERVKTESSEALKAEKRKLI---------KDKV 400
++A EKK E+ PE P +PE V E A E+ + K V
Sbjct: 10642 KVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPV 10701
Query: 401 GKKHLKEKISKLEEKKDKEKKEIKKE---RKELKKDEGRKEEKKDAKKEEKRKDTKPELK 457
+K ++K E + E+ KE K++ +K E AK E K+ PE K
Sbjct: 10702 PEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPE-K 10760
Query: 458 KIS---KPDLKPF-TPEV-RKTLYKAK----VPGRVKIDRSRAIRGEKELSSEPQTPPAQ 508
K++ KP++ P PEV +K + + K VP R + +E++ E + P +
Sbjct: 10761 KVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEE 10820
Query: 509 KGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGP 568
+ VP+ E P + ++ +++ E++ + ++ + +P P E+
Sbjct: 10821 EKPVPV----AEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEK-- 10874
Query: 569 PSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWEEKKQ 628
++ PP P +E V ++ + +P+++ + + E K EKK
Sbjct: 10875 --PKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKV 10932
Query: 629 REA--ERLPDRTEA----------REESEPEVKEDVIEKAELEEMEEVHPSDEEEEDATK 676
R+ ER P+ E EE EP+V+ +EK + + E P EE
Sbjct: 10933 RKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVP 10992
Query: 677 AEGFYQKHMQEPLKVTPRSREAFGGRELGLQGKAPEKETSLFLSSLTTPAGATEHVSYIQ 736
++ + EP KV P + A + L P+ + + ++ P E
Sbjct: 10993 TVTKRERKIPEPTKV-PEIKPA-----IPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAA 11046
Query: 737 DETIPGYSETEQTISDEE--------IHDEPEERPAPPRFHTSTYDLPGPEGAGPFEASQ 788
T+P + + + +E I P++ P+P PG G +
Sbjct: 11047 PVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKL-RPGSGG------EK 11099
Query: 789 PADSAVPATSGKVYGTPETELTYPTNIVAAPLAEEEHVSSATSITEC 835
P D A P T Y L + I L E E V S ++I EC
Sbjct: 11100 PPDEA-PFT----YQLKAVPLKFVKEIKDIILTESEFVGS-SAIFEC 11140
Score = 52.4 bits (124), Expect = 6e-06
Identities = 95/470 (20%), Positives = 180/470 (38%), Gaps = 84/470 (17%)
Query: 290 RYPVATQKDLASGAVPTNLKPSKIKQRADSKESLKAT-TKTAVSKLAKREEVVEEGAKEA 348
+ P +K + +P + K A E K T+ ++ + +REE E
Sbjct: 9343 KVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEI 9402
Query: 349 RSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALK---AEKRKLIKDKVGKKHL 405
+ E K + +E PP+ PA P++ E A+ A+K + +V KK +
Sbjct: 9403 PKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTV 9462
Query: 406 KEKISKLEEKK-----------DKEKKEIKKERKELKKDEG---------RKEEKKDAKK 445
E+ + E+K + + ++E +++EG +EE+++A+
Sbjct: 9463 VEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEV 9522
Query: 446 EEKRKDTKPE-----------LKKISKPDLKPFTPEVRKTLYKAKVPGRV---------- 484
E +PE K++ + + +K + K K+P ++
Sbjct: 9523 TEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPE 9582
Query: 485 ---KIDRSRAIRG---EKELSSEPQTPPAQKGTVPLPTISGH-RELVLSSPEDLTQDFEE 537
KI + + +KE P+ P K VP + ++ P +T+ +
Sbjct: 9583 APKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQ 9642
Query: 538 MKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPP-SVPGLGQEEHVMKEKELV 596
+ +EE+ L+A T +E PP + P +VP EE V+K K
Sbjct: 9643 ITQEEKVLVAV--------------TKKEAPPKARVPEEPKRAVP----EEKVLKLKPKR 9684
Query: 597 PEVP-------EEQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVK 649
E P ++ K+ + A E + E E ER E + E +
Sbjct: 9685 EEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEE 9744
Query: 650 EDVIEKAELEEMEEVHPSDE----EEEDATKAEGF--YQKHMQEPLKVTP 693
+ E+ + +E EE P++E EE + + E + +++++ EP K P
Sbjct: 9745 YEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIP 9794
Score = 51.2 bits (121), Expect = 1e-05
Identities = 116/576 (20%), Positives = 210/576 (36%), Gaps = 103/576 (17%)
Query: 339 EVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKD 398
E V GAKE + + K A A + E P +T A + ++
Sbjct: 407 EAVATGAKEVKQDADKSAAVATVVAAVDMARVRE-PVISAVEQTAQRTTTTAVHIQPAQE 465
Query: 399 KVGKKHLKEKISKLEEKKDKEKK-EIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELK 457
+V K+ K ++K+ DK K+ E+K KE+ K+E+ E+ RK+T+
Sbjct: 466 QVRKEAEKTAVTKVVVAADKAKEQELKSRTKEVITT---KQEQMHVTHEQIRKETEKTF- 521
Query: 458 KISKPDLKPFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTI 517
+ K + + ++T ++ + K AIR E E+++ A + L T+
Sbjct: 522 -VPKVVISAAKAKEQETRISEEITKKQKQVTQEAIRQETEITAASMVVVATAKSTKLETV 580
Query: 518 SGHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTP 577
G +E + + + +E++ +E R + + I TP
Sbjct: 581 PGAQEETTTQQDQMHLSYEKIMKETRKTVVPK----------------------VIVATP 618
Query: 578 PSVPGLGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDR 637
+KE++LV RG + E+ +EK ++EAE+
Sbjct: 619 K-----------VKEQDLV----------SRGREGITTKREQVQITQEKMRKEAEKTALS 657
Query: 638 TEAREESEPEVKEDVIEKAEL-----EEMEEVH----PSDEEEEDATKAEGFYQKHMQEP 688
T A ++ + +E ++ E E+++ H + E AT Q ++EP
Sbjct: 658 TIAVATAKAKEQETILRTRETMATRQEQIQVTHGKVDVGKKAEAVATVVAAVDQARVREP 717
Query: 689 LKVTPRSREAFGGRELGLQGKAPEKETSLFLSSLTTPAGATEHVSYIQDETIPGYSETEQ 748
RE G ++ ++T+L G E +S + P +E
Sbjct: 718 -------------REPGHLEESYAQQTTL-------EYGYKERISAAKVAEPPQRPASEP 757
Query: 749 TISDEEIHDEPEERPAPPRFHTSTYDLPGPEGAGPFEAS-------------QPADSAVP 795
+ + + +P AP H T D G + + + +P ++
Sbjct: 758 HVVPKAV--KPRVIQAPSETHIKTTDQKGMHISSQIKKTTDLTTERLVHVDKRPRTASPH 815
Query: 796 ATSGKVYGTPETELTYPTNIVAAPLA----EEEHVSSATSITECDKLSSFATSV----AE 847
T K+ P+TE Y +I + +A E SSA IT+ K + S AE
Sbjct: 816 FTVSKI-SVPKTEHGYEASIAGSAIATLQKELSATSSAQKITKSVKAPTVKPSETRVRAE 874
Query: 848 DQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEAT 883
+ T +T KS ++ + S T T
Sbjct: 875 PTPLPQFPFADTPDTYKSEAGVEVKKEVGVSITGTT 910
Score = 46.6 bits (109), Expect = 3e-04
Identities = 77/340 (22%), Positives = 132/340 (38%), Gaps = 63/340 (18%)
Query: 293 VATQKDLASGAVPTNLKPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSEL 352
+A ++++A P KP + + + + A + K+ ++V EA
Sbjct: 10810 IAPEEEIA----PEEEKPVPVAEEEEPEVPPPAVPEEP-KKIIPEKKVPVIKKPEAPPPK 10864
Query: 353 AKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKL 412
E K +K K PP PA P+ E LKA +K + + K + EK+
Sbjct: 10865 EPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPE---KPQVPEKVELT 10921
Query: 413 EEKKDKEKKEIKK---ERK-ELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFT 468
K +K+++K ERK E K++ K + +EE+ K +L+K+ KP +
Sbjct: 10922 PLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVP--E 10979
Query: 469 PEVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSP 528
P K + + +VP K +R EP P K +PLP +P
Sbjct: 10980 PPPPKPVEEVEVPTVTKRERK---------IPEPTKVPEIKPAIPLP-----------AP 11019
Query: 529 EDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEH 588
E + E+K KP P++ P T I P +VP +G
Sbjct: 11020 EPKPKPEAEVKT---------------IKPPPVE-----PEPTPI-AAPVTVPVVG---- 11054
Query: 589 VMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWEEKKQ 628
K+ + P+E+ +K +G G + E+++
Sbjct: 11055 ----KKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRK 11090
Score = 43.5 bits (101), Expect = 0.003
Identities = 50/233 (21%), Positives = 104/233 (44%), Gaps = 28/233 (12%)
Query: 373 KPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKE-RKELK 431
K + ++V T+ + + +K+ ++++++ +K L+ + K+ E K +EK +K+E K L
Sbjct: 32945 KDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALKEEASKVLI 33004
Query: 432 KDEGRKEEKKDAKK----EEKRKDTKPELKKISKPDLKPFTPEV-----RKTLYKAKVPG 482
+E +K +K EE K ++ + + ++K F+ ++ ++ + KA + G
Sbjct: 33005 SEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG 33064
Query: 483 R---------VKIDRSRAIR----GEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPE 529
V++ S R G + + Q +G L IS +E ++
Sbjct: 33065 ATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGI--LTCISKTKEGIVKCQY 33122
Query: 530 DLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAE-EGPPSTAIQGTPPSVP 581
DLT E + A +++ R + + L T E G PS I+ ++P
Sbjct: 33123 DLTLSKE--LSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLP 33173
Score = 37.0 bits (84), Expect = 0.27
Identities = 109/534 (20%), Positives = 187/534 (35%), Gaps = 86/534 (16%)
Query: 1201 EESPSKETSLDVSSKQLSPESLGTLQ------FGELNLGKEEMGHLMQA-EDTSHHTAPM 1253
EE P+K+T VS+ Q+S ++ F ++ EM A + H T P
Sbjct: 197 EEVPAKKTKTIVSTAQISESRQTRIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPR 256
Query: 1254 SVPEPHAATASPPTDGTTRYSAQTDITDDSLDRKSPASSFSHSTPSGNGKYLPGAITSPD 1313
P+P + + +PP+ A+ SP TPS P SP
Sbjct: 257 IPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPS------PVRSVSPA 310
Query: 1314 EHILTPDSSFSKSPESLPGPALEDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQ----- 1368
I T +SP + +A E P ++ E E ++ L
Sbjct: 311 ARISTSPIRSVRSPLLMRKTQASTVATGPEVPPPWKQEGYVASSSEAEMRETTLTTSTQI 370
Query: 1369 QKDKTLEHKEVVEPKDTAIYQKDEALHVKN------EAVKQQDKALEQKGRDLEQKDTAL 1422
+ ++ E + V+ + T A V EAV K ++Q T +
Sbjct: 371 RTEERWEGRYGVQEQVTISGAAGAAASVSASASYAAEAVATGAKEVKQDADKSAAVATVV 430
Query: 1423 EQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKD 1482
D A ++ E A+EQ TA A+
Sbjct: 431 AAVDMA-------------------RVREPVISAVEQ--TAQRTTTTAVH---------- 459
Query: 1483 RVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDK 1542
+ +E++ +E +K KV KA E E+K R E EQ H EQ K
Sbjct: 460 -IQPAQEQVRKEAEKTAVTKVVVAADKAKEQ---ELKSRTKEVITTKQEQMHVTHEQIRK 515
Query: 1543 VSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQE---QESLVQEDKTRKPKML--- 1596
+EK K K A EQ + EE + Q+ QE++ QE + M+
Sbjct: 516 ETEK---TFVPKVVISAAK--AKEQETRISEEITKKQKQVTQEAIRQETEITAASMVVVA 570
Query: 1597 -------------EEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRG 1643
+E++ + M E ++++T+ + + +V + +EQ+
Sbjct: 571 TAKSTKLETVPGAQEETTTQQDQMHLSYEKIMKETRKTVVPKVIVATPKVKEQDLVSRGR 630
Query: 1644 QDVVQEWQETSPTREEPAGEQKELA---PAWEDTSPEQDNRYWRGREDVALEQD 1694
+ + + ++ T+E+ E ++ A A ++ R RE +A Q+
Sbjct: 631 EGITTKREQVQITQEKMRKEAEKTALSTIAVATAKAKEQETILRTRETMATRQE 684
Score = 35.0 bits (79), Expect = 1.0
Identities = 52/232 (22%), Positives = 91/232 (39%), Gaps = 17/232 (7%)
Query: 341 VEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKV 400
VEE K+ R K E + + A + K + E +L++
Sbjct: 32151 VEETRKDFRYSTYHIPTKAEASTSYAELRERHAQAAYRQPKQRQRIMAEREDEELLRPVT 32210
Query: 401 GKKHLKEKISKLE----EKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPEL 456
+HL E S+L+ E+K ++K ++E E+ + E E K A++E ++
Sbjct: 32211 TTQHLSEYKSELDFMSKEEKSRKKSRRQREVTEITEIEEEYEISKHAQRESSSSASRLLR 32270
Query: 457 KKISKPDLKPFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPT 516
++ S L P E+ + V ++ A E + TP + P P
Sbjct: 32271 RRRS---LSPTYIELMR-----PVSELIRSRPQPAEEYEDDTERRSPTPERTRPRSPSP- 32321
Query: 517 ISGHREL---VLSSPEDLTQDFEEMKRE-ERALLAEQRDTGLGDKPFPLDTA 564
+S R L S+ D+ +E MK + +E++ L +PF LD A
Sbjct: 32322 VSSERSLSRFERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQPFTLDHA 32373
Score = 33.5 bits (75), Expect = 3.0
Identities = 49/241 (20%), Positives = 101/241 (41%), Gaps = 21/241 (8%)
Query: 320 KESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPER 379
+++ + TT TAV +E+V +E K A +++ K +++ +S K + +
Sbjct: 447 EQTAQRTTTTAVHIQPAQEQVRKEAEKTAVTKVVVAADKAKEQELKSRTKEVITTKQEQM 506
Query: 380 VKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKE--RKELK------ 431
T + EK + K + KE+ +++ E+ K++K++ +E R+E +
Sbjct: 507 HVTHEQIRKETEKTFVPKVVISAAKAKEQETRISEEITKKQKQVTQEAIRQETEITAASM 566
Query: 432 -----KDEGRKEEKKDAKKEEKRKDTKPEL--KKISKPDLKPFTPEVRKTLYKAKVPGRV 484
+ E A++E + + L +KI K K P+V K K V
Sbjct: 567 VVVATAKSTKLETVPGAQEETTTQQDQMHLSYEKIMKETRKTVVPKVIVATPKVKEQDLV 626
Query: 485 KIDRS--RAIRGEKELSSEPQTPPAQK---GTVPLPTISG-HRELVLSSPEDLTQDFEEM 538
R R + +++ E A+K T+ + T +E +L + E + E++
Sbjct: 627 SRGREGITTKREQVQITQEKMRKEAEKTALSTIAVATAKAKEQETILRTRETMATRQEQI 686
Query: 539 K 539
+
Sbjct: 687 Q 687
Score = 32.3 bits (72), Expect = 6.8
Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 21/100 (21%)
Query: 2000 LSTKEAAAGRNTSAEKELSSPISPKSLQSDTPTFSYAALAGPTVPPRPEPGPSMEPSLTP 2059
+ST + + R T EK++ + +S+ + AA G +P + TP
Sbjct: 208 VSTAQISESRQTRIEKKIEAHFDARSIATVEMVIDGAA--GQQLPHK-----------TP 254
Query: 2060 PAVPPRAPILSKGPSPP------LNGNILSCSPDRRSPSP 2093
P +PP+ S+ P+PP S SP R SPSP
Sbjct: 255 PRIPPKPK--SRSPTPPSIAAKAQLARQQSPSPIRHSPSP 292
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 138 bits (347), Expect = 9e-32
Identities = 88/370 (23%), Positives = 209/370 (56%), Gaps = 22/370 (5%)
Query: 1336 EDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALH 1395
E++ + E+K+ L+++ EQ+K E +++ +Q+++ + +E + ++ +++++E +
Sbjct: 383 EEMMWEKEEKIRELEEKMHEQEKIREQEEK--RQEEEKIREQEKRQEQEAKMWRQEEKIR 440
Query: 1396 VKNEAVKQQDKALEQKGRDLEQKDTALE----QKDKALEPKDKDLEEKDKALEQKDKIPE 1451
+ E +++Q+K + ++ + +++ E Q+ + + +++ + E+++ QK+K+ E
Sbjct: 441 EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHE 500
Query: 1452 EKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAP 1511
+++K +Q++ Q++K E ++K EQ++++ Q+EKI E+++ +++ + K
Sbjct: 501 QEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIW 560
Query: 1512 EDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQA 1571
E+ ++ EQ DK Q+ + +EQ++KV ++++ EQ+ Q+++ +Q +
Sbjct: 561 EE------EKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
Query: 1572 LEENHQTQEQESLV--QEDKTRKPKMLEEKSPEKVKAMEEKL----EALLEKTKALGLEE 1625
E+ + QEQE + QE+K R+ + + ++ EK+ EEK+ E + E+ + + +E
Sbjct: 615 REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQE 674
Query: 1626 SLV--QEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYW 1683
+ QE + REQEEK ++++QE +E +EE EQ+E E+ Q+ + W
Sbjct: 675 EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 734
Query: 1684 RGREDVALEQ 1693
++V L Q
Sbjct: 735 --EQEVRLRQ 742
Score = 131 bits (329), Expect = 1e-29
Identities = 86/320 (26%), Positives = 190/320 (59%), Gaps = 20/320 (6%)
Query: 1343 EDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVK 1402
E+K+ +++ EQ+K+ ++E + +++K E ++ E ++ +++++E +H + E +
Sbjct: 436 EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE--MWRQEEKIHEQEEIWR 493
Query: 1403 QQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDT 1462
Q++K EQ+ + +Q++ Q++K E ++K E+++K Q++KI E+++ + +++
Sbjct: 494 QKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEE--MWREEE 551
Query: 1463 ALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKA--LDQKVRSVEHKAPEDTVAEMKD 1520
+ +++K E ++K EQ+D++ Q+EKI E+++K ++K+R E K E ++
Sbjct: 552 KMHEQEKIWE-EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKR-----QEQEE 605
Query: 1521 RDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQE 1580
+ +Q +K EQ+ + QEQ++K+ E++++ EQ+ Q+++ EQ + E+ + QE
Sbjct: 606 KMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQE 665
Query: 1581 QESLV--QEDKTR----KPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLV--QEGR 1632
QE + QE+K R K + EEK E+ + M+E+ E + E+ + + +E + QE +
Sbjct: 666 QEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 725
Query: 1633 AREQEEKYWRGQDVVQEWQE 1652
R QEEK W + +++ +E
Sbjct: 726 MRRQEEKMWEQEVRLRQQEE 745
Score = 129 bits (323), Expect = 5e-29
Identities = 111/497 (22%), Positives = 247/497 (49%), Gaps = 46/497 (9%)
Query: 1316 ILTPDSSFSKSPESLPGPALEDIAIKWEDKVPG--LKDRTSEQKKEP---------EPKD 1364
+L P + L G L+ ++ K + +V L +R ++Q++E E ++
Sbjct: 256 LLLPQQQLQAEADHL-GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEE 314
Query: 1365 EVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQ 1424
++ +Q++K E +E + ++ + +++E + K E +++Q++ + +K + +++ + +
Sbjct: 315 KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 374
Query: 1425 KDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRV 1484
K++ + +++ + EK++ + + ++ E++K EQ++ Q+++ + ++K EQ+ ++
Sbjct: 375 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK--RQEEEKIREQEKRQEQEAKM 432
Query: 1485 LEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVS 1544
Q+EKI E+++K +Q E + +++ EQ E+K Q QE+ +
Sbjct: 433 WRQEEKIREQEEKIREQ----------EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 482
Query: 1545 EKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKV 1604
EK + +++ W +K E+ I+ EE QE++ QE+K R+ + + EK+
Sbjct: 483 EKIHE--QEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI 540
Query: 1605 KAMEE---------KLEALLEKTKALGLEESL-VQEGRAREQEEKYWRGQDVVQEWQETS 1654
+ EE + E + E+ K E+ + QE + REQEEK WR ++ ++E +E
Sbjct: 541 REQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKR 600
Query: 1655 PTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQDTYWRELSCERKVWFPHELDG 1714
+EE +Q+E E+ EQ+ + R +E+ EQ+ E++ E++ + +
Sbjct: 601 QEQEEKMWKQEEKIREQEEKIQEQEEKI-REQEEKIREQE----EMTQEQEEKMGEQEEK 655
Query: 1715 QGARPHYTEEREST-FLDEGPDDEQEVPLREHATRSPWASDFKDFQESSPQKGLEVERWL 1773
+ +E+E T + E EQE +RE + + ++ + +K E E +
Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEK---IREQEEMMQEQEEKMWEQEEKM 712
Query: 1774 AESPVGLPPEEEDKLTR 1790
E + E+E+K+ R
Sbjct: 713 CEQEEKM-QEQEEKMRR 728
Score = 125 bits (315), Expect = 4e-28
Identities = 111/444 (25%), Positives = 219/444 (49%), Gaps = 34/444 (7%)
Query: 1352 RTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQK 1411
R E+ K P+ ++ + D + + V K A +++E + N+ +Q++K Q+
Sbjct: 249 RKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQ--QQEEKMWRQE 306
Query: 1412 GRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKAL 1471
+ E ++ EQ++K E ++K E+++K Q++ + E+++K Q++ E+++K
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366
Query: 1472 EPKDKDLEQKDRVLEQKEKI--PEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKA 1529
++ E+++++ Q+E + EEK + L++K+ E K E ++ + + +K
Sbjct: 367 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE-KIREQEEKRQEEEKIREQEKR 425
Query: 1530 PEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQE----QESLV 1585
EQ+ + Q++K+ E++++ EQ+ Q+++ EQ EE Q QE QE +
Sbjct: 426 QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 485
Query: 1586 QEDK---TRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWR 1642
E + +K KM E++ EK++ EEK+ EK + QE + REQEEK WR
Sbjct: 486 HEQEEIWRQKEKMHEQE--EKIRKQEEKVWRQEEKIRE--------QEEKIREQEEKMWR 535
Query: 1643 GQDVVQEWQETSPTREEPAGEQKELAPAWEDTS-PEQDNRYWRGREDVALEQDTYWRELS 1701
++ ++E QE EE EQ+++ WE+ EQ+++ WR E + +++ WR+
Sbjct: 536 QEEKIRE-QEEMWREEEKMHEQEKI---WEEEKRQEQEDKMWRQEEKIREQEEKVWRQ-- 589
Query: 1702 CERKVWFPHELDGQGARPHYTEERESTFLDEGPDDEQEVPLREHATRSPWASDFKDFQES 1761
E K+ E + + +E E E EQE +RE + + ++ +
Sbjct: 590 -EEKIREQEEKRQEQEEKMWKQE-EKIREQEEKIQEQEEKIREQEEK---IREQEEMTQE 644
Query: 1762 SPQKGLEVERWLAESPVGLPPEEE 1785
+K E E + E + +EE
Sbjct: 645 QEEKMGEQEEKMCEQEEKMQEQEE 668
Score = 124 bits (311), Expect = 1e-27
Identities = 86/310 (27%), Positives = 180/310 (58%), Gaps = 31/310 (10%)
Query: 1336 EDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALH 1395
E I+ E+K ++ +++K E ++E+ +QK+K E +E + ++ +++++E +
Sbjct: 462 EQEKIREEEKRQEQEEMWRQEEKIHE-QEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIR 520
Query: 1396 VKNEAVKQQDKAL---EQKGRDLEQ---KDTALEQKDKALEPKDKDLEEKDKALEQKDKI 1449
+ E +++Q++ + E+K R+ E+ ++ + +++K E ++K E++DK Q++KI
Sbjct: 521 EQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWE-EEKRQEQEDKMWRQEEKI 579
Query: 1450 PEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHK 1509
E+++K Q++ EQ++K E ++K +Q++++ EQ+EKI E+++K +Q
Sbjct: 580 REQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQ-------- 631
Query: 1510 APEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNI 1569
E+ + E ++ EQ +K EQ+ + EQ++K+ E+ E+ W Q+++ EQ
Sbjct: 632 --EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ-----EETMWR--QEEKIREQEK 682
Query: 1570 QALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQ 1629
+ E+ + +EQE ++QE ++ KM E++ EK+ EEK++ EK + E+ Q
Sbjct: 683 KIREQEEKIREQEEMMQE---QEEKMWEQE--EKMCEQEEKMQEQEEKMRRQE-EKMWEQ 736
Query: 1630 EGRAREQEEK 1639
E R R+QEEK
Sbjct: 737 EVRLRQQEEK 746
Score = 106 bits (264), Expect = 4e-22
Identities = 109/440 (24%), Positives = 202/440 (45%), Gaps = 49/440 (11%)
Query: 1364 DEVLQQKDKTLEHK-EVVEPKDTAIYQKDEALHVKNEAVK------QQDKALEQKGRDLE 1416
DE L++K+ L+ K ++VE + + I + L K E K Q + G++L+
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 275
Query: 1417 QKDTALEQKDKALEPKDK-DLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKD 1475
L+ + + E ++ + ++++K Q++KI E ++K EQ++ EQ
Sbjct: 276 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQ--------- 326
Query: 1476 KDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHK--APEDTVAEMKDRDLEQTDKAPEQK 1533
E+K R E+K + EE ++K+R E E+ + ++ E+ +K Q+
Sbjct: 327 ---EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE 383
Query: 1534 HQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLV--QEDKTR 1591
E+++K+ E +++ EQ+ ++ E Q + + E + QEQE+ + QE+K R
Sbjct: 384 EMMWEKEEKIRELEEKMHEQEKI---REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 440
Query: 1592 KPKMLEEKSPEKVKAMEEKL---EALLEKTKALGLEESLVQEGRAREQEEKYWRGQDVVQ 1648
+ + + +K+ EEK+ E + E+ K EE QE + EQEE WR ++ +
Sbjct: 441 EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE-IWRQKEKMH 499
Query: 1649 EWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQDTYWRELSCERKVWF 1708
E +E +EE Q+E E+ EQ+ + WR E + EQ+ WRE E K+
Sbjct: 500 EQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIR-EQEEMWRE---EEKM-- 553
Query: 1709 PHELDGQGARPHYTEERESTFLDEGPDDEQEVPLREHATRSPWASDFKDFQESSPQKGLE 1768
HE + E+ + + E EQE W + K ++ ++ E
Sbjct: 554 -HEQEKIWEEEKRQEQEDKMWRQEEKIREQE--------EKVWRQEEKIREQEEKRQEQE 604
Query: 1769 VERWLAESPVGLPPEEEDKL 1788
+ W E + E+E+K+
Sbjct: 605 EKMWKQEEKI---REQEEKI 621
Score = 103 bits (257), Expect = 2e-21
Identities = 60/232 (25%), Positives = 144/232 (62%), Gaps = 10/232 (4%)
Query: 1343 EDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPK-----DTAIYQKDEALHVK 1397
E+K+ +++ Q+++ ++E+ ++++K E +++ E + + +++++E + +
Sbjct: 523 EEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQ 582
Query: 1398 NEAV-KQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKA 1456
E V +Q++K EQ+ + EQ++ +Q++K E ++K E+++K EQ++KI E+++
Sbjct: 583 EEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMT 642
Query: 1457 LEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVA 1516
EQ++ EQ++K E ++K EQ++ + Q+EKI E++ K +Q+ + E E+ +
Sbjct: 643 QEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQ---EEMMQ 699
Query: 1517 EMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQN 1568
E +++ EQ +K EQ+ + QEQ++K+ ++++ EQ+ L Q++E ++++
Sbjct: 700 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV-RLRQQEEKMQEH 750
Score = 100 bits (250), Expect = 2e-20
Identities = 67/262 (25%), Positives = 151/262 (57%), Gaps = 16/262 (6%)
Query: 1343 EDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVK 1402
E+K+ +++ Q+++ ++E ++++++ + +E + +++++E +H + E +
Sbjct: 502 EEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMH-EQEKIW 560
Query: 1403 QQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDT 1462
+++K EQ+ + Q++ EQ++K ++K E+++K EQ++K+ ++++K EQ++
Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEK 620
Query: 1463 ALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTV--AEMKD 1520
EQ++K E ++K EQ++ EQ+EK+ E+++K +Q+ + E E+T+ E K
Sbjct: 621 IQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ---EETMWRQEEKI 677
Query: 1521 RDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQE 1580
R+ E+ + E+K +EQ++ + E+ E+K W +K E+ +Q EE + QE
Sbjct: 678 REQEKKIREQEEK--IREQEEMMQEQ-----EEKMWEQEEKMCEQEEKMQEQEEKMRRQE 730
Query: 1581 QESLVQEDKTRKPKMLEEKSPE 1602
++ QE + R+ EEK E
Sbjct: 731 EKMWEQEVRLRQQ---EEKMQE 749
Score = 74.3 bits (181), Expect = 2e-12
Identities = 96/485 (19%), Positives = 208/485 (42%), Gaps = 71/485 (14%)
Query: 311 SKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEK- 369
+K++ + + E + K+ ++EE ++E +E E +++ + E+K +E EK
Sbjct: 279 AKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEW-EEKIQEQEEKIREQEEKIREQEEKM 337
Query: 370 ---------PPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEK 420
EK + E + E E ++ ++ +++ +K K +E++ +E+K +E
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE-EMMWEKEEKMRRQEEMMWEKEEKIREL 396
Query: 421 KEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPEL----KKISKPDLKPFTPEVRKTLY 476
+E E++++++ E +++E++ +++EKR++ + ++ +KI + + K E +
Sbjct: 397 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ 456
Query: 477 KAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFE 536
+ K+ + KI + ++E+ + + Q+ +E + E+ E
Sbjct: 457 EEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQE 516
Query: 537 EMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELV 596
E RE+ + EQ + + + + EE + +EE M E+E +
Sbjct: 517 EKIREQEEKIREQEEK-MWRQEEKIREQEE----------------MWREEEKMHEQEKI 559
Query: 597 PEVPEEQGSKD-----------------RGLDSGAETEEEKDTWEEKKQREAERLPDRTE 639
E + Q +D R + E EE++ EEK ++ E++ ++ E
Sbjct: 560 WEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEE 619
Query: 640 AREESEPEVKEDVIEKAELEEM--EEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSRE 697
+E E +++E + E EEM E+ E+EE + E + MQE + R E
Sbjct: 620 KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE----EKMQEQEETMWRQEE 675
Query: 698 AFGGRELGLQGKAPEKETSLFLSSLTTPAGATEHVSYIQDETIPGYSETEQTISDEEIHD 757
+E K E+E + E +Q++ + + E+ EE
Sbjct: 676 KIREQE----KKIREQEEKI-----------REQEEMMQEQEEKMWEQEEKMCEQEEKMQ 720
Query: 758 EPEER 762
E EE+
Sbjct: 721 EQEEK 725
Score = 70.1 bits (170), Expect = 3e-11
Identities = 77/357 (21%), Positives = 164/357 (45%), Gaps = 15/357 (4%)
Query: 333 KLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEK 392
K+ ++EE++ E KE + +E ++K +E EK E+ E+ K + EA +
Sbjct: 378 KMRRQEEMMWE--KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 435
Query: 393 RKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEE---KR 449
+ I+++ K +EK +E+K E+++I++E K +++E ++E+K ++EE ++
Sbjct: 436 EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQK 495
Query: 450 KDTKPELKKISKPDLKPFTPE--VRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPA 507
+ + +KI K + K + E +R+ K + + IR ++E+ E +
Sbjct: 496 EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHE 555
Query: 508 QKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEG 567
Q+ + + E + + E++ R+E + ++ ++ +
Sbjct: 556 QEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIR 615
Query: 568 PPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAET--EEEKDTW-E 624
IQ + QEE + +++E+ E E+ G ++ + E E+E+ W +
Sbjct: 616 EQEEKIQEQEEKIRE--QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQ 673
Query: 625 EKKQREAE-RLPDRTEAREESEPEVKEDVIEKAELEE--MEEVHPSDEEEEDATKAE 678
E+K RE E ++ ++ E E E ++E + E EE E+ E+EE + E
Sbjct: 674 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 730
Score = 61.2 bits (147), Expect = 1e-08
Identities = 74/369 (20%), Positives = 172/369 (46%), Gaps = 35/369 (9%)
Query: 308 LKPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESS 367
++ + K++ + K + + +K+ ++EE + E ++ R E K++ + E+K E
Sbjct: 406 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR-EQEKKMWRQEEKIHE-Q 463
Query: 368 EKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKER 427
EK E+ + E+ + E E+ ++ + K +EKI K EEK +++++I+++
Sbjct: 464 EKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQE 523
Query: 428 KELKKDE---GRKEEKKDAKKEEKRKDTK-PELKKISKPDLKPFTPEVRKTLYKAKVPGR 483
+++++ E R+EEK ++E R++ K E +KI + + + E +++ + +
Sbjct: 524 EKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKR---QEQEDKMWRQE--EK 578
Query: 484 VKIDRSRAIRGEKEL--SSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKRE 541
++ + R E+++ E + +K I E + E + + E+++ +
Sbjct: 579 IREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQ 638
Query: 542 ERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPE 601
E + ++++ +G++ + EE QEE + +++E + E +
Sbjct: 639 EE--MTQEQEEKMGEQEEKMCEQEEKMQE--------------QEETMWRQEEKIREQEK 682
Query: 602 ---EQGSKDRGLDSGAETEEEKDTW--EEKKQREAERLPDRTEAREESEPEVKEDVIEKA 656
EQ K R + + +EEK W EEK + E++ ++ E E ++ E +
Sbjct: 683 KIREQEEKIREQEEMMQEQEEK-MWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 741
Query: 657 ELEEMEEVH 665
+ EE + H
Sbjct: 742 QQEEKMQEH 750
Score = 56.6 bits (135), Expect = 3e-07
Identities = 81/370 (21%), Positives = 165/370 (44%), Gaps = 51/370 (13%)
Query: 323 LKATTKTAVSKLAKREEVVEEGAKEARSELAKELAK---TEKKAKESSEKPPEKPAKPER 379
L+ ++ K + +EE KE R L+ EL + T+++ KE + K EK E
Sbjct: 177 LEQALSAVATQKKKADRYIEELTKE-RDALSLELYRNTITDEELKEKNAKLQEKLQLVES 235
Query: 380 VKTESSEALKAEKRKLIKDK--VGKKHLKEKISKL--EEKKDKEKKEIKKERKELKKDEG 435
K+E +K KRKL + K + ++ L+ + L E + K + + E EL
Sbjct: 236 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 295
Query: 436 RKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVKIDRSRAIRGE 495
+++E+K ++EEK ++ + ++++ + ++ ++R+ K + + ++ +R +
Sbjct: 296 QQQEEKMWRQEEKIQEWEEKIQE-QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 354
Query: 496 KELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALL-AEQRDTGL 554
+E+ E + E + E + + E+M+R+E + E++ L
Sbjct: 355 EEMMWEKE------------------EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 396
Query: 555 GDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKDRGLDSGA 614
+K + E QEE ++E+ E +EQ +K +
Sbjct: 397 EEKMHEQEKIREQEEKR-------------QEEEKIREQ----EKRQEQEAKMWRQEEKI 439
Query: 615 ETEEEKDTWEEKKQ-REAERLPDRTEAREESEPEVKEDVIEKAE-LEEMEEV----HPSD 668
+EEK +EKK R+ E++ ++ + REE + + +E++ + E + E EE+
Sbjct: 440 REQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMH 499
Query: 669 EEEEDATKAE 678
E+EE K E
Sbjct: 500 EQEEKIRKQE 509
Score = 53.1 bits (126), Expect = 4e-06
Identities = 79/405 (19%), Positives = 178/405 (43%), Gaps = 26/405 (6%)
Query: 309 KPSKIKQRADSKESLKATTKTAVSKLAKREE-----VVEEGAKEARSELAKELAKTEKKA 363
K +K++++ ES K+ + V +L ++ E + ++ + L KEL K
Sbjct: 222 KNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL 281
Query: 364 KESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEI 423
+ E+ R+ + E + ++ K+ + + + +EKI + EEK ++++++
Sbjct: 282 QAQVEENELW----NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 337
Query: 424 KKERKEL--KKDEGRKEEKKDAKKEEKRKDTKPEL----KKISKPDLKPFTPEVRKTLYK 477
+++ + + K+++ R++E+ +KEEK + + + +K+ + + + E + +
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 397
Query: 478 AKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTV--PLPTISGHRELVLSSPEDLTQDF 535
K+ + KI R E+E E + Q+ + I E + + + +
Sbjct: 398 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE 457
Query: 536 EEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKEL 595
E++ +E+ E+R ++ E+ I + QEE + K++E
Sbjct: 458 EKIHEQEKIREEEKRQ----EQEEMWRQEEKIHEQEEIWRQKEKMH--EQEEKIRKQEEK 511
Query: 596 V---PEVPEEQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVKEDV 652
V E EQ K R + +EEK +E+ RE E++ ++ + EE + + +ED
Sbjct: 512 VWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDK 571
Query: 653 IEKAELEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSRE 697
+ + E + E+ +EE + E Q+ ++ K + RE
Sbjct: 572 MWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIRE 616
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 136 bits (342), Expect = 3e-31
Identities = 117/476 (24%), Positives = 240/476 (50%), Gaps = 54/476 (11%)
Query: 1343 EDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVK 1402
E+K+ + R EQ+KE +++ L+++ + E +E ++ ++ +++++E + + E +
Sbjct: 313 EEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMW 372
Query: 1403 QQDKAL----------EQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEE 1452
+Q++ L EQK RD E++ + ++D+ L K++ + E++K EQ +K+ EE
Sbjct: 373 RQEERLWEQEKQMREQEQKMRDQEER---MWEQDERLREKEERMREQEKMWEQVEKMREE 429
Query: 1453 K-----DKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRS-V 1506
K +K ++ ++++++ E + K E+++ + EQ+EK+ ++++ +Q+ +
Sbjct: 430 KKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQ 489
Query: 1507 EHKAPE--------DTVAEMKDRDLEQTDKAPEQKHQ-AQEQK----DKVSEKKDQALEQ 1553
+ + PE + + E +++ EQ +K +Q+ QE+K +K+ E++DQ EQ
Sbjct: 490 QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 549
Query: 1554 KYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEA 1613
+ Q+ + +Q + +E+ Q QE+++ QE+K R+ EE+ E+ K M E+ E
Sbjct: 550 EEKMRDQEQKMWDQE-ERMEKKTQEQEKKTWDQEEKMRE----EERMREREKKMREEEEM 604
Query: 1614 LLEKTKALGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWED 1673
+ E+ E+ QE + +EQEEK W ++ +QE +E +EE EQ+E WE
Sbjct: 605 MREQE-----EKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE--KMWEQ 657
Query: 1674 TS-PEQDNRYWRGREDVALEQDTYWRELSCERKVWFPHELDGQGARPHYTEERESTFLDE 1732
PEQ + W + EQ+ + E K+W +++ + + +E
Sbjct: 658 QRLPEQKEKLW--EHEKMQEQEKMQEQ---EEKIWEQEKMEKKTQEQEKKTWDQEKMREE 712
Query: 1733 GPDDEQEVPLREHATRSPWASDFKDFQESSPQKGLEVERWLAESPVGLPPEEEDKL 1788
E+E +RE + QE Q+ E E W E + E+E+K+
Sbjct: 713 ESMREREKKMREEEEMMREQEEKMQEQEEKMQE-QEEEMWEQEEKMW---EQEEKM 764
Score = 130 bits (327), Expect = 2e-29
Identities = 119/528 (22%), Positives = 245/528 (46%), Gaps = 54/528 (10%)
Query: 1352 RTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQK 1411
R E+ +E E K + +Q++K +E + ++ + +++E + + + +++Q+K L ++
Sbjct: 276 RQEEELREQEKK--IRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQ 333
Query: 1412 GRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKAL 1471
++L ++ EQ+++ E ++K E+++K EQ++K+ ++++ EQ+ EQ+ K
Sbjct: 334 EKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 393
Query: 1472 EPKDKDLEQKDRVLEQKEKI--------------PEEKDKALDQKVRSVEHKAPED---T 1514
+ +++ EQ +R+ E++E++ E+K + ++K R E K E+
Sbjct: 394 DQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIR 453
Query: 1515 VAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKD---QALEQKYWALGQKDEALEQNIQA 1571
E K R+ E+T + E+K Q QE+ E+K+ Q L ++ L ++++ EQ +
Sbjct: 454 EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKI 513
Query: 1572 LEENHQTQEQESLVQEDKT--RKPKMLEE-----KSPEKVKAMEEKL----EALLEKT-- 1618
E+ + ++QE + ++K R+ KM E+ + EK++ E+K+ E + +KT
Sbjct: 514 WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQE 573
Query: 1619 ---KALGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTS 1675
K EE + +E R RE+E+K +++++E +E +EE EQ+E E+
Sbjct: 574 QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKM 633
Query: 1676 PEQDNRYWRGREDVALEQDTYWRELSC---ERKVWFPHELDGQGARPHYTEERESTFLDE 1732
EQ+ + W E + +++ W + + K+W ++ Q E+ E
Sbjct: 634 QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKME 693
Query: 1733 GPDDEQEVPLREHATRSPWASDFKDFQES--SPQKGLEVERWLAESPVGLPPEEEDKLTR 1790
EQE + W + +ES +K + E + E+E+K+
Sbjct: 694 KKTQEQE--------KKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQE 745
Query: 1791 SPFEIISPPASPPEMVGQRVPSAPGQESPIPDPKLMPHMKNEPTTPSW 1838
E+ +M Q Q P KL H K + W
Sbjct: 746 QEEEMWE---QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIW 790
Score = 130 bits (326), Expect = 2e-29
Identities = 89/368 (24%), Positives = 203/368 (55%), Gaps = 12/368 (3%)
Query: 1352 RTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQK 1411
+ EQ+K+ ++E +Q++++ E ++ + ++ + +++E + + E + +Q++ Q+
Sbjct: 431 KMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQ 490
Query: 1412 GRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEK-----DKALEQKDTALEQ 1466
R EQK+ EQ +K E ++K E+++K +Q++ +EK +K EQ+D EQ
Sbjct: 491 QRLPEQKEKLWEQ-EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 549
Query: 1467 KDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEH-KAPEDTVAEMKDRDLEQ 1525
++K + + K +Q++R +E+K + E+K ++K+R E + E + E ++ EQ
Sbjct: 550 EEKMRDQEQKMWDQEER-MEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 608
Query: 1526 TDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLV 1585
+K EQ+ + QEQ++K+ E++++ EQ+ Q+++ EQ + E+ +++E L
Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLW 668
Query: 1586 QEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQD 1645
+ +K ++ + ++E+ EK+ E+ + E+ K +E + +E RE+E+K ++
Sbjct: 669 EHEKMQEQEKMQEQE-EKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEE 727
Query: 1646 VVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQDTYW--RELSCE 1703
+++E +E +EE EQ+E E+ EQ+ + W ++ + +++ W ++ +
Sbjct: 728 MMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWE-QQRLPEQKEKLWEHEKMQEQ 786
Query: 1704 RKVWFPHE 1711
K+W E
Sbjct: 787 EKIWEQEE 794
Score = 129 bits (324), Expect = 4e-29
Identities = 100/410 (24%), Positives = 215/410 (52%), Gaps = 23/410 (5%)
Query: 1343 EDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVK 1402
+ ++P K++ EQ+K E ++++ +Q++K + +E+ ++ ++++++ +++ +
Sbjct: 490 QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWG-QEKKMWRQEKMREQEDQMWE 548
Query: 1403 QQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEK----DKALEQKDKIPEEKDKALE 1458
Q++K +Q+ + +Q++ +E+K + E K D EEK ++ E++ K+ EE++ E
Sbjct: 549 QEEKMRDQEQKMWDQEER-MEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 607
Query: 1459 QKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEH-KAPEDTVAE 1517
Q++ EQ++K E ++K EQ++++ EQ+EK+ E+++K +Q+ + E + PE
Sbjct: 608 QEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL 667
Query: 1518 MKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYW---ALGQKDEALEQNIQALEE 1574
+ +++ +K EQ+ + EQ+ EKK Q E+K W + +++ E+ + EE
Sbjct: 668 WEHEKMQEQEKMQEQEEKIWEQEKM--EKKTQEQEKKTWDQEKMREEESMREREKKMREE 725
Query: 1575 NHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAR 1634
+EQE +QE + + + EE+ E+ + M E+ E + E+ + +E L + + +
Sbjct: 726 EEMMREQEEKMQEQEEKMQEQ-EEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ 784
Query: 1635 EQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQD 1694
EQ EK W ++ +++ +E +EE Q+E E+ Q+ + W E + +++
Sbjct: 785 EQ-EKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEE 843
Query: 1695 TYW-RELSCERKVWFPHELDGQGARPHYTEERESTFLDEGPDDEQEVPLR 1743
W +E E K+ QG E+ E E EQE +R
Sbjct: 844 KMWGQEEKMEEKM--------QGQEEKMREQEEKMRGQEEKMREQEEKMR 885
Score = 125 bits (314), Expect = 6e-28
Identities = 99/380 (26%), Positives = 206/380 (54%), Gaps = 39/380 (10%)
Query: 1343 EDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVK 1402
E K+ + +T +Q+++ + ++ + +++ K E +E + ++ + +++E + + E
Sbjct: 429 EKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEW 488
Query: 1403 QQDKALEQKGR------DLEQKDTALEQKDKALEP-----KDKDLEEKDKALEQKDKIPE 1451
QQ + EQK + EQ++ EQ++K + ++K + ++K EQ+D++ E
Sbjct: 489 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWE 548
Query: 1452 EKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKI-PEEKDKALDQKVRSVEH-- 1508
+++K +Q+ +Q+++ + K EQ+ + +Q+EK+ EE+ + ++K+R E
Sbjct: 549 QEEKMRDQEQKMWDQEERM---EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 605
Query: 1509 KAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQ--KYWALGQKDEALE 1566
+ E+ + E +++ EQ +K EQ+ + QEQ++K+ E++++ EQ K W + + L
Sbjct: 606 REQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW----EQQRLP 661
Query: 1567 QNIQALEENHQTQEQESL-VQEDKTRKPKMLEEKSPEKVKAM--EEKL---EALLEKTKA 1620
+ + L E+ + QEQE + QE+K + + +E+K+ E+ K +EK+ E++ E+ K
Sbjct: 662 EQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKK 721
Query: 1621 LGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTS-PEQD 1679
+ EE ++ REQEEK ++ +QE +E +EE EQ+E WE PEQ
Sbjct: 722 MREEEEMM-----REQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEE--KMWEQQRLPEQK 774
Query: 1680 NRYWRGREDVALEQDTYWRE 1699
+ W + EQ+ W +
Sbjct: 775 EKLW--EHEKMQEQEKIWEQ 792
Score = 119 bits (298), Expect = 4e-26
Identities = 98/462 (21%), Positives = 226/462 (48%), Gaps = 38/462 (8%)
Query: 1352 RTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQK 1411
R E+ K P+ + +++ +E + ++ I +++E + + E +++Q+ + ++
Sbjct: 253 RKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQ 312
Query: 1412 GRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKAL 1471
+ +++ L +++K L ++K+L E+ + EQ++++ E+++K EQ++ EQ++K
Sbjct: 313 EEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMW 372
Query: 1472 EPKDKDLEQKDRVLEQKEKIPEEKDK--ALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKA 1529
+++ EQ+ ++ EQ++K+ +++++ D+++R E + E +++ EQ +K
Sbjct: 373 RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMRE------QEKMWEQVEKM 426
Query: 1530 PEQKH-QAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQED 1588
E+K Q QE+K + E+K Q E++ +K E+ ++ EE Q QE+ QE+
Sbjct: 427 REEKKMQEQEKKTRDQEEKMQE-EERIREREKKMREEEETMREQEEKMQKQEENMWEQEE 485
Query: 1589 KTRKPKMLEEK-----SPEKVKAMEEKL----EALLEKTKALGLEESLVQEGRAREQEEK 1639
K + + L E+ EK++ EEK+ E + ++ + G E+ + ++ + REQE++
Sbjct: 486 KEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQ 545
Query: 1640 YWRGQDVVQEWQETSPTREEPAGE--QKELAPAWEDTSPEQDNRYWRGREDVALEQDTYW 1697
W ++ +++ ++ +EE + Q++ W+ ++ R RE E++
Sbjct: 546 MWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 605
Query: 1698 RE------------LSCERKVWFPHELDGQGARPHYTEERESTFLDEGPDDEQEVPLREH 1745
RE E K+W E + + +E + +E ++Q +P ++
Sbjct: 606 REQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKE 665
Query: 1746 ATRSPWASDFKDFQESSPQKGLEVERWLAESPVGLPPEEEDK 1787
W + + QE + E + W E E+E K
Sbjct: 666 KL---W--EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKK 702
Score = 114 bits (286), Expect = 1e-24
Identities = 94/363 (25%), Positives = 194/363 (53%), Gaps = 35/363 (9%)
Query: 1335 LEDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEAL 1394
+ D K D+ ++ +T EQ+K+ ++E ++++++ E ++ + ++ + +++E +
Sbjct: 553 MRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKM 612
Query: 1395 HVKNEAVKQQDKAL-EQKGRDLEQKDTALEQKDKALEPKDKDLEE------KDKALEQKD 1447
+ E +++Q++ + EQ+ + EQ++ EQ++K E ++K E+ K+K E +
Sbjct: 613 QEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEK 672
Query: 1448 KIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVE 1507
+E++K EQ++ EQ+ + + K EQ+ + +Q++ EE + ++K+R
Sbjct: 673 M--QEQEKMQEQEEKIWEQE----KMEKKTQEQEKKTWDQEKMREEESMREREKKMRE-- 724
Query: 1508 HKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQ 1567
E+ + E +++ EQ +K EQ+ + EQ++K+ E+ E+K W + + L +
Sbjct: 725 ---EEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQ-----EEKMW----EQQRLPE 772
Query: 1568 NIQALEENHQTQEQESL-VQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEES 1626
+ L E+ + QEQE + QE+K R + EK++ EEK+ ++ K G EE
Sbjct: 773 QKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRG--QEEKMWGQEEK 830
Query: 1627 L-VQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRG 1685
+ QE + QEEK W GQ+ ++ +E +EE EQ+E E+ EQ+ + RG
Sbjct: 831 MWGQEEKMWGQEEKMW-GQE--EKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEK-MRG 886
Query: 1686 RED 1688
+E+
Sbjct: 887 QEE 889
Score = 111 bits (278), Expect = 9e-24
Identities = 113/472 (23%), Positives = 226/472 (47%), Gaps = 59/472 (12%)
Query: 1349 LKDRTSE-QKKEP---EPKDEV---LQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAV 1401
LK + +E Q+K P K E+ +++ + LE + + P+ ++E + E
Sbjct: 223 LKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELR 282
Query: 1402 KQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKD 1461
+Q+ K +Q+ + Q++ EQ+ K E ++K ++ + EQ+ ++ E++ + EQK+
Sbjct: 283 EQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKE 342
Query: 1462 TALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDR 1521
EQ+++ E ++K EQ++++ EQ+EK+ ++++ +Q+ +M+
Sbjct: 343 LR-EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE-------------KQMR-- 386
Query: 1522 DLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQ-KYWALGQKDEALEQNIQALEENHQTQE 1580
EQ K +Q+ + EQ +++ EK+++ EQ K W ++ E + + + E+ +T++
Sbjct: 387 --EQEQKMRDQEERMWEQDERLREKEERMREQEKMW---EQVEKMREEKKMQEQEKKTRD 441
Query: 1581 QESLVQED---KTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQE 1637
QE +QE+ + R+ KM EE+ E ++ EEK++ ++ EE Q+ R EQ+
Sbjct: 442 QEEKMQEEERIREREKKMREEE--ETMREQEEKMQK--QEENMWEQEEKEWQQQRLPEQK 497
Query: 1638 EKYWRGQDVVQEWQETSPTREEPAGEQKEL----APAW-EDTSPEQDNRYWRGREDVALE 1692
EK W Q+ +QE +E +EE +Q+E+ W ++ EQ+++ W E + +
Sbjct: 498 EKLWE-QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQ 556
Query: 1693 QDTYW--------RELSCERKVWFPHELDGQGAR-----PHYTEERESTFLDEGPDDEQE 1739
+ W + E+K W E + R EE E E EQE
Sbjct: 557 EQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE 616
Query: 1740 VPLREHATRSPWASDFKDFQESSPQKGLEVERWLAESPVGLP---PEEEDKL 1788
++E + W + K ++ E + W E + PE+++KL
Sbjct: 617 EKMQEQEEKM-WEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL 667
Score = 107 bits (266), Expect = 2e-22
Identities = 79/295 (26%), Positives = 160/295 (54%), Gaps = 24/295 (8%)
Query: 1336 EDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQ-QKDKTLEHKEVVEPKDTAIYQKDEAL 1394
E++ + E+K+ +++ EQ+++ ++E +Q Q++K E +E + ++ ++++
Sbjct: 602 EEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 661
Query: 1395 HVK-----NEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLE---EKDKALEQK 1446
K +E +++Q+K EQ+ + EQ+ +E+K + E K D E E++ E++
Sbjct: 662 EQKEKLWEHEKMQEQEKMQEQEEKIWEQEK--MEKKTQEQEKKTWDQEKMREEESMRERE 719
Query: 1447 DKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEK------IPEEKDKALD 1500
K+ EE++ EQ++ EQ++K E +++ EQ++++ EQ+EK +PE+K+K +
Sbjct: 720 KKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWE 779
Query: 1501 QKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQ 1560
+ + K E E K RD E+ + E+K + QE+K + E+K E+K W +
Sbjct: 780 HEKMQEQEKIWEQ---EEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEE 836
Query: 1561 KDEALEQNI----QALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKL 1611
K E+ + + +EE Q QE++ QE+K R + + EK++ EEK+
Sbjct: 837 KMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
Score = 87.4 bits (215), Expect = 2e-16
Identities = 89/391 (22%), Positives = 183/391 (46%), Gaps = 38/391 (9%)
Query: 1405 DKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQ-KDKIPEEKDKALE----- 1458
++ L++K +L++K E + ++ K+L+ K LE+ K +P+ + L+
Sbjct: 220 NEELKKKNAELQEKLPLAESEKSEIQLNVKELKRK---LERAKFLLPQVQTNTLQEEMWR 276
Query: 1459 QKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEM 1518
Q++ EQ+ K + ++K Q++R+ EQ+ K+ E+++K Q+ R E ++
Sbjct: 277 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLRE----QEKELRE 332
Query: 1519 KDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQT 1578
++++L + + EQ+ Q QEQ++K+ E++++ EQ E+ + EE
Sbjct: 333 QEKELREQKELREQEEQMQEQEEKMWEQEEKMREQ------------EEKMWRQEERLWE 380
Query: 1579 QEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEE 1638
QE++ QE K R EE+ E+ + + EK E + E+ K E + +E + +EQE+
Sbjct: 381 QEKQMREQEQKMRDQ---EERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEK 437
Query: 1639 KYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQDTYWR 1698
K R Q+ + +E RE+ E++E E+ +Q+ W E +Q R
Sbjct: 438 K-TRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQ----R 492
Query: 1699 ELSCERKVWFPHELDGQGARPHYTEERESTFLDEGPDDEQEVPLREHATRSPWASDFKDF 1758
+ K+W ++ Q + E+ E E +++ R+ R + + +
Sbjct: 493 LPEQKEKLWEQEKMQEQEEK--IWEQEEKIRDQEEMWGQEKKMWRQEKMRE---QEDQMW 547
Query: 1759 QESSPQKGLEVERWLAESPVGLPPEEEDKLT 1789
++ + E + W E + +E++K T
Sbjct: 548 EQEEKMRDQEQKMWDQEERMEKKTQEQEKKT 578
Score = 77.4 bits (189), Expect = 2e-13
Identities = 61/253 (24%), Positives = 133/253 (52%), Gaps = 37/253 (14%)
Query: 1343 EDKVPGLKDRTSEQKKEPEPKD-----EVLQQKDKTLEHKEVV--EPKDTAIYQKDEALH 1395
E+K+ +++ EQ++ PE K+ E +Q+++K E +E + + K Q+ E
Sbjct: 644 EEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKT 703
Query: 1396 VKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDK 1455
E +++++ E++ + E+++ EQ++K E ++K E++++ EQ++K+ E+++K
Sbjct: 704 WDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEK 763
Query: 1456 ALEQKDTALEQKDKA-----LEPKDKDLEQKDRVLEQKEKI--PEEKDKALDQKVRSVEH 1508
EQ+ EQK+K ++ ++K EQ++++ +Q+EK+ EEK + ++K+R E
Sbjct: 764 MWEQQRLP-EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEE 822
Query: 1509 KA----------------------PEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEK 1546
K ++ E K + E+ + E+K + QE+K + E+
Sbjct: 823 KMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEE 882
Query: 1547 KDQALEQKYWALG 1559
K + E+K + +G
Sbjct: 883 KMRGQEEKIYCVG 895
Score = 73.9 bits (180), Expect = 2e-12
Identities = 77/360 (21%), Positives = 165/360 (45%), Gaps = 37/360 (10%)
Query: 314 KQRADSK-ESLKATTKTAVSKLAKREEVVEEGAK-EARSELAKELAKTEKKAKESSEKPP 371
K R + K + + T+ K+ + E + E K E +E + +K +E+ +
Sbjct: 425 KMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 484
Query: 372 EKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELK 431
EK + +R+ + + + EK + ++K+ ++ +EKI EE +EKK ++E+ +
Sbjct: 485 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQ--EEKIRDQEEMWGQEKKMWRQEKMREQ 542
Query: 432 KDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVKIDRSRA 491
+D+ ++E+K +E+K D + ++K ++ K + K + ++ +R +
Sbjct: 543 EDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMR-----EREKK 597
Query: 492 IRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLAEQRD 551
+R E+E+ E + ++ E + E+ + EE +E+ + EQ +
Sbjct: 598 MREEEEMMREQEEKMQEQ------------EEKMQEQEEKMWEQEEKMQEQEEKMWEQEE 645
Query: 552 TGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKDRGLD 611
E+ Q P L + E M+E+E + E E+ +++ ++
Sbjct: 646 K----------MWEQEEKMWEQQRLPEQKEKLWEHEK-MQEQEKMQEQEEKIWEQEK-ME 693
Query: 612 SGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIEKAELEEMEEVHPSDEEE 671
+ E+EK TW+++K RE E + +R + E E ++E ++ +++E EE EEE
Sbjct: 694 KKTQ-EQEKKTWDQEKMREEESMREREKKMREEEEMMRE---QEEKMQEQEEKMQEQEEE 749
Score = 70.5 bits (171), Expect = 2e-11
Identities = 106/452 (23%), Positives = 189/452 (41%), Gaps = 65/452 (14%)
Query: 1382 PKDTA-----IYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALE-----QKDKALEP 1431
P+DT + ++ +A H EA++++ +A + R L + T LE +D A +
Sbjct: 69 PEDTQQNRAQLKEEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKF 128
Query: 1432 KDKDLEEKDK---ALEQKDK-----------IP-EEKDKA--LEQKDTALEQKDKALEPK 1474
+D +L AL Q + IP E KD A L + +AL
Sbjct: 129 EDGNLGTPSSFNLALSQAFRGSPLGCVSTSLIPGESKDLAGRLHHSWHFAGELQRALSAV 188
Query: 1475 DKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKH 1534
++ DR +E+ K ++ S+E T E+K ++ E +K P +
Sbjct: 189 STRHKKADRYIEELTK---------ERDALSLELYRNTITNEELKKKNAELQEKLPLAES 239
Query: 1535 QAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDK----- 1589
+ E + V E K + K+ + L++ + EE + QE++ QE+K
Sbjct: 240 EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQE 299
Query: 1590 ------TRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESL-VQEGRAREQEEKYWR 1642
K + EEK + K + E+ + L E+ K L ++ L QE + +EQEEK W
Sbjct: 300 ERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWE 359
Query: 1643 GQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYW------RGREDVALEQDTY 1696
++ ++E +E +EE EQ++ E +Q+ R W R +E+ EQ+
Sbjct: 360 QEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKM 419
Query: 1697 WRELSCERKVWFPHELDGQGARPHYTEERESTFLDEGPDDEQEVPLREHATRSPWASDFK 1756
W ++ R+ E + + T ++E +E E+E +RE +
Sbjct: 420 WEQVEKMREEKKMQEQEKK------TRDQEEKMQEEERIREREKKMREEEETMREQEEKM 473
Query: 1757 DFQESSPQKGLEVERWLAESPVGLPPEEEDKL 1788
QE + + E E W + PE+++KL
Sbjct: 474 QKQEENMWEQEEKE-WQQQR----LPEQKEKL 500
Score = 67.4 bits (163), Expect = 2e-10
Identities = 84/426 (19%), Positives = 207/426 (48%), Gaps = 33/426 (7%)
Query: 304 VPTN-LKPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKK 362
V TN L+ +Q + +E K K K+ ++EE + E + R E +++ + EK+
Sbjct: 265 VQTNTLQEEMWRQEEELREQEKKIRKQE-EKMWRQEERLREQEGKMR-EQEEKMWRQEKR 322
Query: 363 AKESSE--KPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEK 420
+E + + EK + ++ E E ++ ++ K+ + + + +EK+ + EE+ +++
Sbjct: 323 LREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 382
Query: 421 KEIKKERKELKKDEGR--KEEKKDAKKEEKRKDTKPELKKISK-PDLKPFTPEVRKTL-- 475
K+++++ ++++ E R +++++ +KEE+ ++ + +++ K + K + +KT
Sbjct: 383 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQ 442
Query: 476 -YKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQD 534
K + R++ +R + +R E+E E Q QK + PE +
Sbjct: 443 EEKMQEEERIR-EREKKMREEEETMRE-QEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL 500
Query: 535 FEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKE 594
+E+ K +E+ +++ + D+ ++ ++ QE+ + +++E
Sbjct: 501 WEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR---------EQEDQMWEQEE 551
Query: 595 LVPEVPEEQGSKDRGLDSGAETEEEKDTW-EEKKQREAERLPDRTEAREESEPEVKEDVI 653
+ + ++ ++ ++ + E+EK TW +E+K RE ER+ +R + E E ++E
Sbjct: 552 KMRDQEQKMWDQEERMEKKTQ-EQEKKTWDQEEKMREEERMREREKKMREEEEMMRE--- 607
Query: 654 EKAELEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFGGRE-LGLQGKAPE 712
++ +++E EE E+EE + E +K ++ K+ + + + E + Q + PE
Sbjct: 608 QEEKMQEQEE--KMQEQEEKMWEQE---EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPE 662
Query: 713 KETSLF 718
++ L+
Sbjct: 663 QKEKLW 668
Score = 65.5 bits (158), Expect = 7e-10
Identities = 84/397 (21%), Positives = 178/397 (44%), Gaps = 57/397 (14%)
Query: 302 GAVPTNLKPSKIKQRADSKE-------SLKATTKTAVSKLAKREEVVEEGAKEARSELAK 354
G V T+L P + K A L+ ++ K + +EE KE R L+
Sbjct: 153 GCVSTSLIPGESKDLAGRLHHSWHFAGELQRALSAVSTRHKKADRYIEELTKE-RDALSL 211
Query: 355 ELAK---TEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDK-----VGKKHLK 406
EL + T ++ K+ + + EK E K+E +K KRKL + K V L+
Sbjct: 212 ELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQ 271
Query: 407 EKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKP 466
E++ + EE+ +++K+I+K+ +++ + E R E++ +E++ K + E + L+
Sbjct: 272 EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKR------LRE 325
Query: 467 FTPEVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTV--PLPTISGHRELV 524
E+R ++ + +R +KEL + + Q+ + + E +
Sbjct: 326 QEKELR--------------EQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKM 371
Query: 525 LSSPEDLTQDFEEMKREERALLAE-----QRDTGLGDKPFPLDTAEEGPPSTAIQGTPPS 579
E L + ++M+ +E+ + + ++D L +K + E+
Sbjct: 372 WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK---------MWEQ 422
Query: 580 VPGLGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTW---EEKKQREAERL-- 634
V + +E+ + ++++ + E+ ++R + + EE++T EEK Q++ E +
Sbjct: 423 VEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 482
Query: 635 PDRTEAREESEPEVKEDVIEKAELEEMEEVHPSDEEE 671
+ E +++ PE KE + E+ +++E EE EE+
Sbjct: 483 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 519
Score = 62.4 bits (150), Expect = 6e-09
Identities = 78/370 (21%), Positives = 162/370 (43%), Gaps = 45/370 (12%)
Query: 318 DSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKP 377
D +E ++ T+ K +EE + E +E E K++ + E+ +E EK E+ K
Sbjct: 562 DQEERMEKKTQEQEKKTWDQEEKMRE--EERMREREKKMREEEEMMREQEEKMQEQEEKM 619
Query: 378 ERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRK 437
+ E E + ++ K+ + + +EK+ + EEK E++ + +++++L + E +
Sbjct: 620 Q----EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM-WEQQRLPEQKEKLWEHEKMQ 674
Query: 438 EEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKE 497
E++K ++EEK + + KK + + K + E + + +R + +R E+E
Sbjct: 675 EQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMR-------EREKKMREEEE 727
Query: 498 LSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGDK 557
+ E + ++ E + E++ + E+M +E + +QR +K
Sbjct: 728 MMREQEEKMQEQ-----------EEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEK 776
Query: 558 PFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEE----QGSKDRGLDSG 613
+ + +E + ++E M+++E EE Q K RG +
Sbjct: 777 LWEHEKMQEQEK-------------IWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEK 823
Query: 614 AETEEEKDTW--EEKKQREAERLPDRTEAREESEPEVKEDVIEKAELEEMEEVHPSDEEE 671
+EEK W EEK + E++ + E EE +E + E+ E +E ++EE
Sbjct: 824 MWGQEEK-MWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEE 882
Query: 672 EDATKAEGFY 681
+ + E Y
Sbjct: 883 KMRGQEEKIY 892
Score = 61.2 bits (147), Expect = 1e-08
Identities = 50/178 (28%), Positives = 95/178 (53%), Gaps = 16/178 (8%)
Query: 1336 EDIAIKWEDKVPGLKDRTSEQKKEP-EPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEAL 1394
E++ + E+K+ +++ EQ++E E ++++ +Q++K E + + E K+
Sbjct: 726 EEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLW------- 778
Query: 1395 HVKNEAVKQQDKALEQ--KGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEE 1452
++E +++Q+K EQ K RD E+K E+K + E K + EEK E+K EE
Sbjct: 779 --EHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEE 836
Query: 1453 KDKALEQK----DTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSV 1506
K E+K + +E+K + E K ++ E+K R E+K + EEK + ++K+ V
Sbjct: 837 KMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKIYCV 894
Score = 58.2 bits (139), Expect = 1e-07
Identities = 88/429 (20%), Positives = 194/429 (45%), Gaps = 50/429 (11%)
Query: 309 KPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSE-LAKELAKTEKKAKESS 367
K ++++++ ES K+ + V +L ++ E + + ++ L +E+ + E++ +E
Sbjct: 226 KNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQE 285
Query: 368 EKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKER 427
+K ++ K R E L+ ++ K+ +++ K +EK + +EK+ +E+++ +E+
Sbjct: 286 KKIRKQEEKMWR----QEERLREQEGKM-REQEEKMWRQEKRLREQEKELREQEKELREQ 340
Query: 428 KELKKDEGRKEEKKDA--KKEEKRKDTKPEL-----------KKISKPDLKPFTPEVRKT 474
KEL++ E + +E+++ ++EEK ++ + ++ K++ + + K E R
Sbjct: 341 KELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER-- 398
Query: 475 LYKAKVPGRVKIDRSR----------AIRGEKELSSEPQTPPAQKGTVPLPTISGHRELV 524
+++ R K +R R +R EK++ + + Q+ + RE
Sbjct: 399 MWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKK 458
Query: 525 LSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLG 584
+ E+ ++ EE +++ + EQ + + P + E+ +Q
Sbjct: 459 MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP-EQKEKLWEQEKMQ---------E 508
Query: 585 QEEHVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWE-EKKQREAERLPDRTEAREE 643
QEE + +++E + + E G + + E+E WE E+K R+ E+ E R E
Sbjct: 509 QEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERME 568
Query: 644 SEPEVKE----DVIEK-AELEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREA 698
+ + +E D EK E E M E EEE+ + + ++ MQE + E
Sbjct: 569 KKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ---EEKMQEQEEKMQEQEEK 625
Query: 699 FGGRELGLQ 707
+E +Q
Sbjct: 626 MWEQEEKMQ 634
Score = 52.4 bits (124), Expect = 6e-06
Identities = 61/327 (18%), Positives = 143/327 (43%), Gaps = 35/327 (10%)
Query: 309 KPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSE 368
+ K+++ + + + K+ ++EE + E +E E +++ + E+K E E
Sbjct: 594 REKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWE-QEEKMQEQEEKMWEQEEKMWEQEE 652
Query: 369 KPPEKPAKPERVKT--ESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKE 426
K E+ PE+ + E + + EK + ++K+ ++ EK ++ +EKK +++++++E
Sbjct: 653 KMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREE 712
Query: 427 RKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVKI 486
++++ +EE++ +++E++ + E + + ++
Sbjct: 713 ESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEM---------------------W 751
Query: 487 DRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMK-REERAL 545
++ + ++E E Q P QK + +E + E + E+M+ +EE+
Sbjct: 752 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMR 811
Query: 546 LAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGS 605
E++ G +K + + G GQEE + ++E + E + Q
Sbjct: 812 GQEEKMRGQEEKMWGQEEKMWGQEEKM----------WGQEEKMWGQEEKMEEKMQGQEE 861
Query: 606 KDRGLDSGAETEEEKDTWEEKKQREAE 632
K R + +EEK +E+K R E
Sbjct: 862 KMREQEEKMRGQEEKMREQEEKMRGQE 888
Score = 32.7 bits (73), Expect = 5.2
Identities = 27/132 (20%), Positives = 61/132 (46%), Gaps = 1/132 (0%)
Query: 333 KLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEK 392
+L +++E + E K E E + + +E EK E E + ++
Sbjct: 769 RLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQE 828
Query: 393 RKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDT 452
K+ + +EK+ EEK + EK + ++E+ ++++ R +E+K ++EEK +
Sbjct: 829 EKMWGQEEKMWGQEEKMWGQEEKME-EKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQ 887
Query: 453 KPELKKISKPDL 464
+ ++ + P +
Sbjct: 888 EEKIYCVGSPPI 899
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 133 bits (335), Expect = 2e-30
Identities = 90/397 (22%), Positives = 211/397 (53%), Gaps = 24/397 (6%)
Query: 1316 ILTPDSSFSKSPESLPGPALEDIAIKWEDKVPG--LKDRTSEQKKEP---------EPKD 1364
+L P + L G L+ ++ K + +V L +R ++Q++E E ++
Sbjct: 317 LLLPQQQLQAEADHL-GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEE 375
Query: 1365 EVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQ 1424
++ +Q++K E +E + ++ + +++E + K E +++Q++ + +K + +++ + +
Sbjct: 376 KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 435
Query: 1425 KDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRV 1484
K++ + ++ + E++K EQ++K EE+ + +++ EQ+ K ++K EQ++++
Sbjct: 436 KEEKIRELEEKMHEQEKIREQEEKRQEEEK--IREQEKRQEQEAKMWRQEEKIREQEEKI 493
Query: 1485 LEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVS 1544
EQ+EK+ +++K +Q+ E K E ++ + + ++ QK + EQ++K+
Sbjct: 494 REQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIR 553
Query: 1545 EKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLV--QEDKTRKPKMLEEKSPE 1602
+++++ Q+ Q+++ EQ + + + +EQE + QE+K R+ + + ++ E
Sbjct: 554 KQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEE 613
Query: 1603 KVKAMEEKL----EALLEKTKALGLEESLV--QEGRAREQEEKYWRGQDVVQEWQETSPT 1656
K+ EEK+ E + E+ + + +E + QE + REQEEK ++++QE +E
Sbjct: 614 KMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 673
Query: 1657 REEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQ 1693
+EE EQ+E E+ Q+ + W ++V L Q
Sbjct: 674 QEEKMCEQEEKMQEQEEKMRRQEEKMW--EQEVRLRQ 708
Score = 120 bits (300), Expect = 2e-26
Identities = 86/349 (24%), Positives = 184/349 (52%), Gaps = 20/349 (5%)
Query: 1352 RTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQK 1411
R E+ K P+ ++ + D + + V K A +++E + N+ +Q++K Q+
Sbjct: 310 RKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQ--QQEEKMWRQE 367
Query: 1412 GRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKAL 1471
+ E ++ EQ++K E ++K E+++K Q++ + E+++K Q++ E+++K
Sbjct: 368 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 427
Query: 1472 EPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPE 1531
++ E+++++ E +EK+ E+ +K+R E K E+ +++ EQ K
Sbjct: 428 RQEEMMWEKEEKIRELEEKMHEQ------EKIREQEEKRQEEEKIREQEKRQEQEAKMWR 481
Query: 1532 QKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTR 1591
Q+ + +EQ++K+ E+ E+K W +++E + + + EE + +++E QE+K R
Sbjct: 482 QEEKIREQEEKIREQ-----EEKMW---RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR 533
Query: 1592 KPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLV-QEGRAREQEEKYWRGQDVVQEW 1650
+ + + + EK+ EEK+ ++ K EE + QE + REQEEK WR ++ ++E
Sbjct: 534 EQEEIWRQK-EKIHEQEEKIRK--QEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQ 590
Query: 1651 QETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQDTYWRE 1699
+E +EE EQ+E+ E+ EQ+ + E + +++ R+
Sbjct: 591 EEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQ 639
Score = 117 bits (293), Expect = 2e-25
Identities = 75/314 (23%), Positives = 177/314 (56%), Gaps = 29/314 (9%)
Query: 1336 EDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALH 1395
E++ + E+K+ L+++ EQ+K E +++ +Q+++ + +E + ++ +++++E +
Sbjct: 430 EEMMWEKEEKIRELEEKMHEQEKIREQEEK--RQEEEKIREQEKRQEQEAKMWRQEEKIR 487
Query: 1396 VKNEAVKQQDKALEQKGRDLEQKDTALE----QKDKALEPKDKDLEEKDKALEQKDKIPE 1451
+ E +++Q++ + ++ + +++ E Q+ + + +++ + E+++ QK+KI E
Sbjct: 488 EQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHE 547
Query: 1452 EKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAP 1511
+++K +Q++ Q++K + ++K EQ+++V Q+EKI E+++K +Q+ + E
Sbjct: 548 QEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQ--- 604
Query: 1512 EDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQA 1571
E+ E +++ EQ +K EQ+ + QEQ++K+ ++++ EQ+ +K E+ I+
Sbjct: 605 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQE-----KKIREQEEKIRE 659
Query: 1572 LEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEG 1631
EE Q QE++ QE+K + + ++ EK++ EEK+ QE
Sbjct: 660 QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM---------------WEQEV 704
Query: 1632 RAREQEEKYWRGQD 1645
R R+QEEK Q+
Sbjct: 705 RLRQQEEKMQEHQE 718
Score = 113 bits (282), Expect = 3e-24
Identities = 68/272 (25%), Positives = 156/272 (57%), Gaps = 16/272 (5%)
Query: 1350 KDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALH----VKNEAVKQQD 1405
+++ EQ+K E + ++ +Q++K E +E + ++ +++++E +H ++ E +Q+
Sbjct: 463 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQ 522
Query: 1406 KALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALE 1465
+ + ++ + +++ QK+K E ++K ++++K Q++K+ ++++K EQ++
Sbjct: 523 EEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWR 582
Query: 1466 QKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQ 1525
Q++K E ++K EQ++++ EQ+E E+++K +Q+ + E E+ + E +++ Q
Sbjct: 583 QEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQ---EEKMQEQEEKMRRQ 639
Query: 1526 TDKAPEQ--KHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQES 1583
+K EQ K + QE+K + E+ Q E+K W Q+++ EQ EE Q QE++
Sbjct: 640 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE--QEEKMCEQ-----EEKMQEQEEKM 692
Query: 1584 LVQEDKTRKPKMLEEKSPEKVKAMEEKLEALL 1615
QE+K + ++ + EK++ +E LEA +
Sbjct: 693 RRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 724
Score = 99.8 bits (247), Expect = 3e-20
Identities = 62/238 (26%), Positives = 137/238 (57%), Gaps = 25/238 (10%)
Query: 1336 EDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALH 1395
E I+ E+K ++ +++K E ++E+ +QK+K E +E + ++ +++++E +H
Sbjct: 509 EQEKIREEEKRQEQEEMWRQEEKIRE-QEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMH 567
Query: 1396 VKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDK 1455
Q++K EQ+ + Q++ EQ++K E ++K E+++ EQ++K+ E+++K
Sbjct: 568 ------DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 621
Query: 1456 ALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTV 1515
EQ++ EQ++K ++K EQ+ ++ EQ+EKI E+ E+ +
Sbjct: 622 MCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ-----------------EEMM 664
Query: 1516 AEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALE 1573
E +++ EQ +K EQ+ + QEQ++K+ ++++ EQ+ L Q++E ++++ + LE
Sbjct: 665 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV-RLRQQEEKMQEHQEHLE 721
Score = 74.3 bits (181), Expect = 2e-12
Identities = 76/386 (19%), Positives = 176/386 (45%), Gaps = 54/386 (13%)
Query: 311 SKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEK- 369
+K++ + + E + K+ ++EE ++E +E E +++ + E+K +E EK
Sbjct: 340 AKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEW-EEKIQEQEEKIREQEEKIREQEEKM 398
Query: 370 ---------PPEKPAKPERVKTESSEALKA------EKRKLIKDKVGKKHLKEKISKLEE 414
EK + E + E E ++ EK + I++ K H +EKI + EE
Sbjct: 399 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 458
Query: 415 KKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKT 474
K+ +E+K ++E+++ ++ + ++E+K ++EEK ++ + ++ + +
Sbjct: 459 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEE------------- 505
Query: 475 LYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQD 534
KI IR E++ + + ++ I +E + E + +
Sbjct: 506 ----------KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQ 555
Query: 535 FEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKE 594
E+M R+E + ++ + ++ + EE I+ + QEE + +++E
Sbjct: 556 EEKMWRQEEKM--HDQEEKIREQEEKVWRQEE-----KIREQEEKI--REQEEKIREQEE 606
Query: 595 LVPEVPEEQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVK--EDV 652
+ E E+ G ++ + E EE+ EEK +R+ E++ ++ + E E +++ E++
Sbjct: 607 MTQEQEEKMGEQEEKM---CEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 663
Query: 653 IEKAELEEMEEVHPSDEEEEDATKAE 678
+++ E + E+ E+EE + E
Sbjct: 664 MQEQEEKMWEQEEKMCEQEEKMQEQE 689
Score = 68.6 bits (166), Expect = 9e-11
Identities = 77/361 (21%), Positives = 156/361 (43%), Gaps = 37/361 (10%)
Query: 1450 PEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHK 1509
PE++ KA Q AL ++ +A + L + L+ + K L+ + R
Sbjct: 168 PEDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEAR----- 222
Query: 1510 APEDTVAEMKDR-----DLEQTDKA-PEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDE 1563
D ++ + D +LEQ A QK +A +++++++D + Y +E
Sbjct: 223 ---DLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEE 279
Query: 1564 ALEQNIQALEENHQTQEQESLVQ------EDKTRKPKMLEEKSPEKVKA--MEEKLEALL 1615
E+N + E+ + ++S +Q + K + K+L + + +A + ++L+++
Sbjct: 280 LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVS 339
Query: 1616 EKTKALGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTS 1675
K +A +EE+ + ++QEEK WR ++ +QEW+E +EE EQ+E E+
Sbjct: 340 AKLQAQ-VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 398
Query: 1676 PEQDNRYWRGREDVALEQDTYWRELSCERK----VWFP----HELDGQGARPHYTEERES 1727
Q+ W E + +++ W + R+ +W EL+ + E+E
Sbjct: 399 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE 458
Query: 1728 TFLDEGPDDEQEVPLREHATRSPWASDFKDFQESSPQKGLEVERWLAESPVGLPPEEEDK 1787
+E EQE R+ W + K ++ + E + W E + E++K
Sbjct: 459 KRQEEEKIREQE--KRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKI----HEQEK 512
Query: 1788 L 1788
+
Sbjct: 513 I 513
Score = 58.5 bits (140), Expect = 9e-08
Identities = 102/497 (20%), Positives = 201/497 (40%), Gaps = 100/497 (20%)
Query: 323 LKATTKTAVSKLAKREEVVEEGAKEARSELAKELAK---TEKKAKESSEKPPEKPAKPER 379
L+ ++ K + +EE KE R L+ EL + T+++ KE + K EK E
Sbjct: 238 LEQALSAVATQKKKADRYIEELTKE-RDALSLELYRNTITDEELKEKNAKLQEKLQLVES 296
Query: 380 VKTESSEALKAEKRKLIK--------------DKVGKK---------------------- 403
K+E +K KRKL + D +GK+
Sbjct: 297 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 356
Query: 404 --------HLKEKISKLEEKKDKEKKEIKKERKELKKDEG--RKEEKKDAKKEEKRKDTK 453
+EKI + EEK +++++I+++ +++++ E R++E+ +KEEK + +
Sbjct: 357 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 416
Query: 454 PEL----KKISKPDLKPFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQK 509
+ +K+ + + + E + + K+ + KI R E+E E + Q+
Sbjct: 417 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 476
Query: 510 GTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPP 569
+ E + E + + E+M R+E + +++ + ++ + E
Sbjct: 477 A-----KMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEK---IREEEKRQEQEEMWRQ 528
Query: 570 STAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWEEKKQR 629
I+ ++E + ++KE + EQ K R + +EEK +E+K R
Sbjct: 529 EEKIR----------EQEEIWRQKEKI----HEQEEKIRKQEEKMWRQEEKMHDQEEKIR 574
Query: 630 EAE----RLPDRTEAREESEPEVKEDVIEKAELEEMEEVHPSDEEEEDATKAEGFYQKHM 685
E E R ++ +EE E +E + E+ E+ + +E ++EE+ + E M
Sbjct: 575 EQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEE-----KM 629
Query: 686 QEPLKVTPRSREAFGGRELGLQGKAPEKETSLFLSSLTTPAGATEHVSYIQDETIPGYSE 745
QE + R E +E K E+E + E +Q++ + +
Sbjct: 630 QEQEEKMRRQEEKIREQE----KKIREQEEKI-----------REQEEMMQEQEEKMWEQ 674
Query: 746 TEQTISDEEIHDEPEER 762
E+ EE E EE+
Sbjct: 675 EEKMCEQEEKMQEQEEK 691
Score = 55.1 bits (131), Expect = 1e-06
Identities = 60/320 (18%), Positives = 146/320 (45%), Gaps = 71/320 (22%)
Query: 333 KLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEK 392
K+ ++E+ E+ AK R E +++ + E+K +E EK + K E ++ E+
Sbjct: 465 KIREQEKRQEQEAKMWRQE--EKIREQEEKIREQEEK-----MWRQEEKIHEQEKIREEE 517
Query: 393 RKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEG--RKEEKKDAKKEEKRK 450
++ ++++ + +E+K +E++EI ++++++ + E RK+E+K ++EEK
Sbjct: 518 KRQEQEEMWR----------QEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMH 567
Query: 451 DTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKG 510
D + +KI + + K + E + + K+ ++ IR ++E++ E + ++
Sbjct: 568 DQE---EKIREQEEKVWRQEEKIREQEEKIR-----EQEEKIREQEEMTQEQEEKMGEQ- 618
Query: 511 TVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPS 570
E + E + + E+M+R+E + +++
Sbjct: 619 ----------EEKMCEQEEKMQEQEEKMRRQEEKIREQEKKI------------------ 650
Query: 571 TAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWEEKKQRE 630
QEE + +++E++ E E+ ++ + E EE+ EEK +R+
Sbjct: 651 ------------REQEEKIREQEEMMQEQEEKMWEQEEKM---CEQEEKMQEQEEKMRRQ 695
Query: 631 AERLPDRTEAREESEPEVKE 650
E++ ++ + E +++E
Sbjct: 696 EEKMWEQEVRLRQQEEKMQE 715
Score = 43.1 bits (100), Expect = 0.004
Identities = 24/119 (20%), Positives = 67/119 (56%), Gaps = 4/119 (3%)
Query: 333 KLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEK---PPEKPAKPERVKTESSEALK 389
K+ ++EE+ +E +E E +++ + E+K +E EK EK + E+ E E ++
Sbjct: 600 KIREQEEMTQE-QEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIR 658
Query: 390 AEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEK 448
++ + + + +EK+ + EEK +++++++++ +++ + E R ++++ +E +
Sbjct: 659 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 717
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 130 bits (328), Expect = 1e-29
Identities = 238/974 (24%), Positives = 334/974 (34%), Gaps = 161/974 (16%)
Query: 1776 SPVGLPPEEEDKLTRSPFEIISP-----PASPPEMVGQRVPSAPGQESPIPDPKLMPHMK 1830
SP G P K +P + P PA+ P G P A SP P P K
Sbjct: 995 SPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPK 1054
Query: 1831 NEPTTPSWLADIPPWVPKDRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAV 1890
PTTP+ P P L AP PA PP+P TP+P G +
Sbjct: 1055 GAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP--KGAPMPPAATPPS 1112
Query: 1891 QEGAAEL---EGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHS--SKVPEASKSHATTE 1945
+G +G P +P A + G A P K + + + P + K T
Sbjct: 1113 PKGGLATPPHKGAPTTP------AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP 1166
Query: 1946 PEQTEPEQREPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEA 2005
P + P TP P + GL P P AA PP A
Sbjct: 1167 PPKGAPTTPAATP-PSPKG-------------GLATPSPKGAPTTPAA--TPPSPKGGLA 1210
Query: 2006 AAGRNTSAEKELSSPISPKSLQSDTPTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPR 2065
+ ++P SPK + TP+ A PP P+ GP+ P P P
Sbjct: 1211 TPSPKGAPTTPAATPPSPKGGLA-TPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAA 1269
Query: 2066 APILSKG--PSPPLNG--NILSCSPDRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKE 2121
P KG +PP G N +P PSPK +TS KGA P
Sbjct: 1270 TPPSLKGGLATPPHKGAPNPAVVTP----PSPKGG------PATSP---PKGAPTPPAAT 1316
Query: 2122 AQSP--SPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFPASAFGFSSLQPAPPQ 2179
SP SP P P G+P T V+PP S G P+S G P
Sbjct: 1317 PPSPKGSPGTPPPKGAP-----TPPAVTPP--SPKGTPTLPATTPSSKGG--------PT 1361
Query: 2180 LPSPAEPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQLPS---- 2235
PS E + P + + G A+ PP+ R P +PS
Sbjct: 1362 TPSSKEGPTPPAATPSHKGGPAMT----PPSPKRG----------------PAIPSPKGD 1401
Query: 2236 PSSPGAPLLSNLPRPASPALSEG----SSSEATTPVISSVAERFSPSLEAAEQESGELDP 2291
P+SP LS PA+P EG S + T P ++ V+ + +P+ A +
Sbjct: 1402 PTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSS 1461
Query: 2292 GMEPAAHSLWDLTPLSPAPPASLDLALAP--APSLPGDMGDGILPCHLECS--------- 2340
+P ++ +P P P + + +P AP+ P MG LP + S
Sbjct: 1462 KGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPS 1521
Query: 2341 ---------EAATEKPSPFQVPSEDCAANGPTETSPNP--------PGPAPAKAENEEAA 2383
K +P + ++ A P T P+P P APA ++EA+
Sbjct: 1522 SRRDPIAPTATLLSKKTPATLAPKE-ALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEAS 1580
Query: 2384 ACPAWERGAWPEGAERSSRPDTLLSPEQPVCPAGGSG-GPPSSASPEVEAGPQGCATEPR 2442
+ PA P + + P LL P P+ PP+ P E GP A +
Sbjct: 1581 SPPA----VTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGT 1636
Query: 2443 PHRGELSPSFL--NPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGG--PCPVTDET 2498
P ++PS L +P P S+ + +T G ++ GP P + T
Sbjct: 1637 PTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKK---GPTALKEVLVAPAPEST 1693
Query: 2499 PPTSASDSGSSQSDSDVPPETEECPSITA----EAALDSDEDGDFLPVDK-----AGGVS 2549
P +A Q+ CP +A + L + LPV K A G
Sbjct: 1694 PIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKD 1753
Query: 2550 GTHHPRPGHDPP------PLPQPD-----PRPSPPRPDVCMADPEGLSSESGRVERLREK 2598
+H P+ PP PL P+P + P L V L K
Sbjct: 1754 ASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPK 1813
Query: 2599 EK-VQGRVGRRAPGKAKPASPARRLDLRGKRSPTPGKG--PADRASRAPPRPRSTTSQVT 2655
++ + G +KP +PA +L P P G P P P+S V
Sbjct: 1814 QQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVP 1873
Query: 2656 PAEEKDGHSPMSKG 2669
K + +KG
Sbjct: 1874 TPSAKQPVTKNNKG 1887
Score = 120 bits (301), Expect = 2e-26
Identities = 228/981 (23%), Positives = 320/981 (32%), Gaps = 125/981 (12%)
Query: 1773 LAESPVGLPPEEED--KLTRSPFEIISPPASPPEMVG--QRVPSAPGQESPIPDPKLMPH 1828
L+ V LPP+E + PF P P+ S+P + P PK +P
Sbjct: 873 LSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPA 932
Query: 1829 MKNEPTTPSWLADIPPWVPKDRPLPP----APLSPAPGPPTPAPESHTPAPFSWGTAEYD 1884
+ P+ A PP PK P P AP PA PP+P TP+P T
Sbjct: 933 SPSPKGAPTPPAATPP-SPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPP-- 989
Query: 1885 SVVAAVQEGAAELEGGPY--SPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHA 1942
AA +GGP SP G A +G A +S P A+
Sbjct: 990 ---AATPPSP---KGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP 1043
Query: 1943 TTEPEQTE-PEQREPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGAA------GD 1995
P T P+ TP S + + PA P G A
Sbjct: 1044 KGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAP 1103
Query: 1996 WPPCLSTKEAAAGRNTSAEK-----ELSSPISPKSLQSDTPTFSYAALAGPTVPPRPEPG 2050
PP + G T K ++P SPK + TP A PP P+ G
Sbjct: 1104 MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLA-TPPPKGAPTTPAATPPSPKGG 1162
Query: 2051 PSMEPSLTPPAVPPRAPILSKG----PSP---PLNGNILSCSPDRRSPSPKESGRSHWDD 2103
+ P P P P KG PSP P SP +P G
Sbjct: 1163 LATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1222
Query: 2104 STSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWP----ETEAHVSPP-------LDS 2152
+T S A P+ +P+ P P G P P T +PP
Sbjct: 1223 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPP 1282
Query: 2153 HLGPARPSLDFPASAFGFSSLQP---AP-PQLPSPAEPRSAPCGSLAFSGDRALALAP-- 2206
H G P++ P S G + P AP P +P P+ +P A+ P
Sbjct: 1283 HKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPS 1342
Query: 2207 --GPPT--RTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSE 2262
G PT T T S + P +PS G P ++ P P +
Sbjct: 1343 PKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTP-PSPKRGPAIPSPKGD 1401
Query: 2263 ATTPVISSVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAPA- 2321
T+P + ++ + +P+ + + A S DLTP + P + L APA
Sbjct: 1402 PTSPAVIPLSPKKAPATPVTREGA---------ATPSKGDLTPPAVTP---VSLKKAPAT 1449
Query: 2322 ------PSLPGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANGPTETSP--NPPGPA 2373
P+ P GD LP + E P+P QV + P +P P PA
Sbjct: 1450 SAPKGGPATPSSKGDPTLPA--VTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPA 1507
Query: 2374 PAKAENEEAAACPAWERG-AWPEGAERSSRPDTLLSPEQPVCPAGGSGGPP--------- 2423
+ +E A P+ R P S + L+P++ + P + P
Sbjct: 1508 VIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTP 1567
Query: 2424 --SSASPEVEAGPQGCATEPRPHRGELSP-SFLNPPLPPSIDDRDLSTEEVRLVGRGGRR 2480
+ A+P + A P ++G SP L PP S ++ T
Sbjct: 1568 KEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPA--------- 1618
Query: 2481 RVGGPGTTGGPCPVTDETPPTSASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFL 2540
V P GP + PTS + SS DS P S+T + + L
Sbjct: 1619 -VTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSP-----ASVTCKMGATVPQASKGL 1672
Query: 2541 PVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEK 2600
P K P + P+ R P P S K
Sbjct: 1673 PAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSA-------KNG 1725
Query: 2601 VQGRVGRRAPGKAKPASPARRLDLRGKRSPTPGKGPADRASRAPPRPRSTTSQVTPAEEK 2660
+G + AP P +GK + KGP APP +++T A EK
Sbjct: 1726 SKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPL-----APPESKASTPLTAAAFEK 1780
Query: 2661 DGHSPMSKGLVNGLKAGPMAL 2681
P S V+ + P++L
Sbjct: 1781 VLPKPESAS-VSAAPSPPVSL 1800
Score = 119 bits (298), Expect = 4e-26
Identities = 220/914 (24%), Positives = 299/914 (32%), Gaps = 156/914 (17%)
Query: 1847 PKDRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLG 1906
PK+ P+ L+ P PT A E+ AP T + + E + P G
Sbjct: 685 PKNHPVKEGTLTTLPLVPT-ASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAG 743
Query: 1907 KDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQ 1966
+ + A AP SS E S + AT + T + +P P
Sbjct: 744 TPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLAD-SPSP------ 796
Query: 1967 YADIYEQMMLTGLGPACPTREPPL--GAAGDWPPC--LSTKEAAAGRNTSAEKELS---S 2019
G+ + T+ PP G+AG P LS+ + + E LS S
Sbjct: 797 ----------LGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGS 846
Query: 2020 PISPKSLQSDTPTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNG 2079
SP + S TP A V P G ++ P TP P +GP+ P
Sbjct: 847 KDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPK 906
Query: 2080 NILSCSPDRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLW 2139
+ S S SPK++ + S KGA P A +P P P W
Sbjct: 907 QAPALS--MTSSSPKKARATPAPKGIPASPSPKGA---PTPPAATPPSPKGGPATPSPKW 961
Query: 2140 PETEAHVSPPLDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGD 2199
T +PP GPA PS P A P PP +P P+ P
Sbjct: 962 APTPPAATPPSPKG-GPATPS---PKGA-------PTPP-AATPPSPKGGPATPSPKGAP 1009
Query: 2200 RALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPLLSNLPR---------- 2249
A+ P P + T P S+ P PS G+P + LP+
Sbjct: 1010 TPPAVTPPSPKGSP-----AATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATL 1064
Query: 2250 ------PASPALSEGSSSEATTPVISSVAERFSPSLEAAEQESGELDP----GMEPAAHS 2299
PA+P+L + A TP S +PS + A P G+ H
Sbjct: 1065 PSPKGGPATPSLKGAPTPPAATPP-SPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHK 1123
Query: 2300 LWDLTPLSPAPPASLDLALAP---APSLPGDM------GDGILPCHLECSEAATEKPSP- 2349
TP + P LA P AP+ P G P + A PSP
Sbjct: 1124 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1183
Query: 2350 --FQVPSEDCAANGPTETSPNPPG----PAPAKAENEEAAACPAWERGAWPEGAERSSRP 2403
PS A P T P+P G P+P A AA P+ + G A S +
Sbjct: 1184 GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL----ATPSPKG 1239
Query: 2404 DTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQ-----GCATEPRPHRGELSPSFLNPPLP 2458
P P GG PP +P A G AT PH+G +P+ + PP P
Sbjct: 1240 APTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATP--PHKGAPNPAVVTPPSP 1297
Query: 2459 PSIDDRDLSTEEVRLVGRGGRRRVGGPGTT---GGPCPVTDETP-----PTSASDSGSSQ 2510
GGP T+ G P P P P + G+
Sbjct: 1298 K-----------------------GGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPT 1334
Query: 2511 SDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDP---PPLPQ-- 2565
+ PP + P T A S + G P K G P P PP P+
Sbjct: 1335 PPAVTPPSPKGTP--TLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRG 1392
Query: 2566 ---PDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASPARRL 2622
P P+ P P V P+ + R G P K PA
Sbjct: 1393 PAIPSPKGDPTSPAVIPLSPK------------KAPATPVTREGAATPSKGDLTPPA-VT 1439
Query: 2623 DLRGKRSP---TPGKGPADRASRAPPRPRSTTSQVTPAEEKDGHSPMSKGLVNGLKAGPM 2679
+ K++P P GPA +S+ P T VTP K+ +P + K P
Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKGDP----TLPAVTPPSPKEPPAPKQVATSSSPKKAPA 1495
Query: 2680 ALSSKGSSGAPVYV 2693
+ G+ P +
Sbjct: 1496 TPAPMGAPTLPAVI 1509
Score = 73.6 bits (179), Expect = 3e-12
Identities = 169/766 (22%), Positives = 257/766 (33%), Gaps = 158/766 (20%)
Query: 2030 TPTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGP------------SPP- 2076
T TF A P P P ++EP T PA AP+ K P SPP
Sbjct: 454 TTTFEVATCVSP--PMSSGPISNIEP--TSPAALVMAPVAPKEPSTQVATTLRIPVSPPL 509
Query: 2077 --------LNGNILSCSPDRRSP------------SPKESGRSHWDDSTSDSELEKGARE 2116
L ++L P ++ SP ++G + D T ++ +
Sbjct: 510 PDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKN 569
Query: 2117 QPEKEAQSPSPPHPI---------PMGSPTLWPETEAHVSPPL-----------DSHLGP 2156
P ++ S SP P+ +G P + + ++ PL DS+ GP
Sbjct: 570 SPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGP 629
Query: 2157 ------ARPSLDFP-ASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPGPP 2209
+ SL P +AF S PA P+ A+ S + + + ++LAP
Sbjct: 630 DSAGPLLKSSLITPTVAAFPLESADPA-GVAPTTAKGTSTYTTTASPFLEGTVSLAP-KN 687
Query: 2210 TRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPLLSNLPRP------ASPALSEGSSSEA 2263
+ + P+ + P PSP + APL + + P SP+L +
Sbjct: 688 HPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPG 747
Query: 2264 TTPVISSVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAP--- 2320
T V + ++ +E D G A S LT L+ + P+ L ++++P
Sbjct: 748 TKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADS-PSPLGVSVSPQTK 806
Query: 2321 -APSLPGDMGD----------------GILPCHLECSEAATEKPSPFQVPSEDCAANGPT 2363
P+ G G LP + + + + P+ P+ PT
Sbjct: 807 RPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPT 866
Query: 2364 ETSPNPPGP-----APAKAENEEAAACPAWERG-AWPEGAERSSRPDTLLSPEQP-VCPA 2416
++ P P P + P + G A P + + T SP++ PA
Sbjct: 867 PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPA 926
Query: 2417 GGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPPLPPSIDDRDLSTEEVRLVGR 2476
G P+S SP+ P AT P P G +PS P PP+
Sbjct: 927 --PKGIPASPSPKGAPTPP-AATPPSPKGGPATPSPKWAPTPPAATPPSPK--------- 974
Query: 2477 GGRRRVGGPGTTGGPCPVTDETPPTSASDSGSSQSDSDVPPETEECPSITAEAALDSDED 2536
GGP T P P TPP + S + P P++T
Sbjct: 975 ------GGPAT---PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVT---------- 1015
Query: 2537 GDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRPDVCMADPEGLSSESGRVERLR 2596
P G + T P+ PP P P+ SP + P ++ + + +
Sbjct: 1016 ----PPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAP---TTPAATLPSPK 1068
Query: 2597 EKEKVQGRVGRRAPGKAKPASPARRLDLRGKRSPTPGKGPADRASRAPPRPRS------- 2649
G P A P SP G +P+P P A+ PP P+
Sbjct: 1069 GGPATPSLKGAPTPPAATPPSPK-----GGPATPSPKGAPMPPAA-TPPSPKGGLATPPH 1122
Query: 2650 ----TTSQVTPAEEKDG-HSPMSKGLVNGLKAGPMALSSKGSSGAP 2690
TT TP K G +P KG A P S KG P
Sbjct: 1123 KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP--SPKGGLATP 1166
Score = 45.8 bits (107), Expect = 6e-04
Identities = 147/659 (22%), Positives = 217/659 (32%), Gaps = 109/659 (16%)
Query: 759 PEERPAPPRFHTSTYDLPGPEGAG-PFEASQPADSAVPATSGKVYGTPETELTYPTNIVA 817
P P P+ +T P P+GA P A+ P+ PAT G P P +
Sbjct: 966 PAATPPSPKGGPAT---PSPKGAPTPPAATPPSPKGGPATPSPK-GAPTPPAVTPPSPKG 1021
Query: 818 APLAEEEHVSSATSITECDKLSSFATSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPS 877
+P +AT + AT + S A+ P+ T ++ L PS
Sbjct: 1022 SP--------AATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATL-------PS 1066
Query: 878 SR----TEATQGLDYVPSAGTISPTS--SLEEDKGFKSPPCEDFSVTGESEKRGEIIGKG 931
+ T + +G P+A SP + KG PP + T S K G
Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPP----AATPPSPKGG------ 1116
Query: 932 LSGERAVEEEEEETANVEMSEKLCSQYGTPVFSAPGHALHPGEPALGEAEERCLSPDDST 991
A + TP G A P + G +P
Sbjct: 1117 -------------LATPPHKGAPTTPAATPPSPKGGLATPPPK---GAPTTPAATPPSPK 1160
Query: 992 VKMASPPPSGPPSATHTPFHQSPVEEKSEPQDFQEADSWGDTKRTPGVGKEDAAEETVKP 1051
+A+PPP G P+ +P P+ S TP P
Sbjct: 1161 GGLATPPPKGAPT--------TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1212
Query: 1052 GPEEGTLEKEEKVPPPRSPQAQEAPVNIDEGLTGCTIQLLPAQDKAIVFEIMEAGEPTGP 1111
P+ P P+ A +P T P K G PT P
Sbjct: 1213 SPKGAPTTPAATPPSPKGGLATPSPKGAPT-----TPAATPPSPKGGPATPPPKGAPTPP 1267
Query: 1112 ILGAEALPGGLRTLPQEPGKPQKDEVL----RYPDRSLSPEDAESLSVLSVPSPDTANQE 1167
+L GGL T P G P V + + P+ A + + PSP +
Sbjct: 1268 AATPPSLKGGLAT-PPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT 1326
Query: 1168 PTPK---SPCGLTEQYLHKDRWPEVSPEDTQSLSLSEESPSKETSLDVSSKQ--LSPESL 1222
P PK +P +T SP+ T +L + S SK SSK+ P +
Sbjct: 1327 PPPKGAPTPPAVTPP----------SPKGTPTLPATTPS-SKGGPTTPSSKEGPTPPAAT 1375
Query: 1223 GTLQFGELNLGKEEMGHLMQAEDTSHHTAPMSVP-EPHAATASPPTDGTTRYSAQTDITD 1281
+ + G T+P +P P A A+P T ++ D+T
Sbjct: 1376 PSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTP 1435
Query: 1282 DSLD----RKSPASSF---SHSTPSGNGKYLPGAIT--SPDEHILTPDSSFSKSPESLP- 1331
++ +K+PA+S +TPS G A+T SP E + S SP+ P
Sbjct: 1436 PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPA 1495
Query: 1332 ------GPALEDIAIKWEDKVPGLKDRTSEQKKEP-EPKDEVLQQK-DKTLEHKEVVEP 1382
P L + +VP T +++P P +L +K TL KE + P
Sbjct: 1496 TPAPMGAPTLPAVIPSSPKEVPA----TPSSRRDPIAPTATLLSKKTPATLAPKEALIP 1550
Score = 40.4 bits (93), Expect = 0.025
Identities = 102/492 (20%), Positives = 168/492 (34%), Gaps = 92/492 (18%)
Query: 759 PEERPAPPRFHTSTYDLPGPEGAGPFEASQPADSAVPATSGKVYGTPETELTYPTNIVAA 818
P+E PAP + TS+ P P A + +P++ +V TP + A
Sbjct: 1475 PKEPPAPKQVATSSSPKKAPATPAPMGAPT-LPAVIPSSPKEVPATPSSRRD-----PIA 1528
Query: 819 PLAEEEHVSSATSITECDKLSSFATSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPSS 878
P A + ++ + L A +V + ++ P+ SS S P +
Sbjct: 1529 PTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSS----KEASSPPA 1584
Query: 879 RTEATQGLDYVPSAGTISPTSSLEEDKGFKSPPCEDFSVTGESEKRGEIIG--KGLSGER 936
T +T P I P + K +PP +VT S ++G KG
Sbjct: 1585 VTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPP----AVTPPSPEKGPATPAPKGTPTSP 1640
Query: 937 AVEEEEEETANVEMSEKLCSQYGTPVFSAPGHALHPGEPALGEAEERCLSPDDSTVKMAS 996
V + + + C T ++ G G AL E + +
Sbjct: 1641 PVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEV-------------LVA 1687
Query: 997 PPPSGPPSATHTPFHQSPVEEKSEPQDFQEADSWGDTKRTPGVGKEDAAEE-------TV 1049
P P P T P + P +KS + +P + + +A+ TV
Sbjct: 1688 PAPESTPIIT-APTRKGPQTKKS-------------SATSPPICPDPSAKNGSKGPLSTV 1733
Query: 1050 KPGP----EEGTLEKEEKVPPPRSPQAQEAPVNIDEG--LTGCTIQ-LLPAQDKAIVFEI 1102
P P ++ + + + SP+ AP LT + +LP + A V
Sbjct: 1734 APAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASV--- 1790
Query: 1103 MEAGEPTGPIL------GAEALPGGLRTLPQEPGKPQKDEVLRYPDRSLSPEDAESLSVL 1156
+ P+ P+ LP + LP PG VL P + L+P D + L L
Sbjct: 1791 --SAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGL-----VLESPSKPLAPADEDELLPL 1843
Query: 1157 SVPSPDTAN--------QEPTPKSPCGLTEQYLHKDRWPEVSPEDTQSLSLSEESPSKET 1208
P P + PTPKS G+ P +P Q ++ + + E+
Sbjct: 1844 IPPEPISGGVPFQSVLVNMPTPKS-AGI----------PVPTPSAKQPVTKNNKGSGTES 1892
Query: 1209 SLDVSSKQLSPE 1220
D S +L +
Sbjct: 1893 DSDESVPELEEQ 1904
Score = 36.6 bits (83), Expect = 0.36
Identities = 64/250 (25%), Positives = 91/250 (36%), Gaps = 20/250 (8%)
Query: 1120 GGLRTLPQEPGKPQKDEVLRYPDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQ 1179
G L TLP P + V P + +P L+ L V +P+ P+P P T
Sbjct: 693 GTLTTLPLVPTASENCPVAPSPQNTCAP-----LATL-VLAPEIPKSVPSPSLPPAGTPP 746
Query: 1180 YLHKDRWPEVSPEDTQSLSLSEESPSKETSLDVSSKQLSPESLGTLQFGELNLGKEEMGH 1239
K T +L+ SP KE + S + S GTL + L +G
Sbjct: 747 GTKKVD----GISHTSALAPVASSP-KECPTEDSGASATASSKGTLTY--LADSPSPLGV 799
Query: 1240 LMQAEDTSHHTAPMSV-PEPHAATASPPTDGTTRYSAQTDITDDSLDRKSPASSFSHSTP 1298
+ + T S P+ S P + + SPA++ S + P
Sbjct: 800 SVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPP 859
Query: 1299 SGNGKYLPGAIT--SPDEHILTPDSSFSKSPESLPGPALEDIAIKWEDKVPGLKDRTSEQ 1356
S G P A+T SP L P + + S +LP P E A + P L +S
Sbjct: 860 SPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPK-EGPATPAPKQAPALSMTSSSP 918
Query: 1357 KK---EPEPK 1363
KK P PK
Sbjct: 919 KKARATPAPK 928
Score = 35.4 bits (80), Expect = 0.80
Identities = 55/219 (25%), Positives = 84/219 (38%), Gaps = 27/219 (12%)
Query: 960 TPVFSAPGHALHPGEPALGEAEERCLSPDDSTVKMASPPPSGPPSATHTPFHQSPVEEKS 1019
TP + P H G PA+ +P A P P G P++ SP + +
Sbjct: 1370 TPPAATPSHK---GGPAM--------TPPSPKRGPAIPSPKGDPTSPAV-IPLSPKKAPA 1417
Query: 1020 EPQDFQEA--DSWGDTKR---TPGVGKEDAAEETVKPGPEEGTLEKEEKVPP--PRSPQA 1072
P + A S GD TP K+ A K GP + + + +P P SP+
Sbjct: 1418 TPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE 1477
Query: 1073 QEAPVNIDEGLTGCTIQLLPAQDKAIVFEIMEAGEPTGPILGAEALPGGLRTLPQEPGKP 1132
AP + T + + PA + + A P+ P A P R +P P
Sbjct: 1478 PPAPKQV---ATSSSPKKAPATPAPMGAPTLPAVIPSSP-KEVPATPSSRR----DPIAP 1529
Query: 1133 QKDEVLRYPDRSLSPEDAESLSVLSVPSPDTANQEPTPK 1171
+ + +L+P++A ++VPSP PTPK
Sbjct: 1530 TATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPK 1568
Score = 34.7 bits (78), Expect = 1.4
Identities = 91/413 (22%), Positives = 140/413 (33%), Gaps = 86/413 (20%)
Query: 2012 SAEKELSSPISPKSLQSDTPTFSYAALAG---PTVPPRPEPGPSMEPSLTPPAVPPRAPI 2068
+ E+EL P + ++ + S A G PT+PP P P + P+
Sbjct: 11 ATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQ------------QCPL 58
Query: 2069 LSKGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEKG-AREQP---EKEAQS 2124
+ + P S P P+ S+S + L G A E P
Sbjct: 59 SAANQASPFPSPSTIASTPLEVPFPQ---------SSSGTALPLGTAPEAPTFLPNLIGP 109
Query: 2125 PSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPA 2184
P P + + SP + P + S L P +SAF PP L +
Sbjct: 110 PISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAF--------PPNLLT-- 159
Query: 2185 EPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAP-- 2242
S P ++A SG AP P+ + + K PS +P+P +P
Sbjct: 160 ---SPPSVAVAESGSVITLSAPIAPSEPK----TNLNKVPS-----EVVPNPKGTPSPPC 207
Query: 2243 LLSNLP----RPASPALSEGSSSEATTPVISSVAERFSPSLEAAEQESGELDPGMEPAAH 2298
++S +P P + S +S TTP + SP ++ S + P P +
Sbjct: 208 IVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIA--SPQVKDTTISSVLISP-QNPGSL 264
Query: 2299 SLWDLTPLSPAPPASLDLALAPA-------------PSLPGDMGDGILPCHL-------- 2337
SL P+SP SL P P P +G + P H
Sbjct: 265 SL--KGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQL 322
Query: 2338 --ECSEAATEKPS--PFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAACP 2386
+ +A P+ V A+ P++ S PP P+ + AA P
Sbjct: 323 LGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFP 375
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 130 bits (327), Expect = 2e-29
Identities = 96/408 (23%), Positives = 212/408 (51%), Gaps = 35/408 (8%)
Query: 1316 ILTPDSSFSKSPESLPGPALEDIAIKWEDKVPG--LKDRTSEQKKEP---------EPKD 1364
+L P + L G L+ ++ K + +V L +R ++Q++E E ++
Sbjct: 256 LLLPQQQLQAEADHL-GKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEE 314
Query: 1365 EVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQ 1424
++ +Q++K E +E + ++ + +++E + K E +++Q++ + +K + + + + +
Sbjct: 315 KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWE 374
Query: 1425 KDKALEPKDKDLEEKDKALEQKDKIPE-----EKDKALEQKDTALEQKDKALEPKDKDLE 1479
K++ + ++ + E++K EQ++K E E++K EQ+ Q++K E ++K E
Sbjct: 375 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 434
Query: 1480 QKDRVLEQKEKI-------PEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQ 1532
Q+ ++ Q+EKI EEK + ++ R E ++ + K++ EQ +K +Q
Sbjct: 435 QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQ-EKIRKQ 493
Query: 1533 KHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRK 1592
+ + Q++K+ +++++ EQ+ Q+++ EQ + E+ + +EQE ++QE + +
Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM 553
Query: 1593 PKMLEE-KSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQDVVQEWQ 1651
+ E+ + EK++ EEK+ EK + Q+ + REQEEK W ++ ++E +
Sbjct: 554 GEQEEKMQEQEKMRRQEEKIREQEEKIRE--------QKEKIREQEEKIWEQEEKIREQE 605
Query: 1652 ETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQDTYWRE 1699
E +EE EQ+E E+ EQ+ + R +E+ EQ+ R+
Sbjct: 606 EMMQEQEEKMWEQEEKMCEQEEKMQEQEEK-MRRQEEKMWEQEVRLRQ 652
Score = 117 bits (292), Expect = 2e-25
Identities = 79/315 (25%), Positives = 182/315 (57%), Gaps = 24/315 (7%)
Query: 1335 LEDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEAL 1394
LE++ + E+K+ L+++ EQ+K E +++ +Q+++ + +E + ++ +++++E +
Sbjct: 368 LEEMMWEKEEKIRELEEKMHEQEKIREQEEK--RQEEEKIREQEKRQEQEAKMWRQEEKI 425
Query: 1395 HVKNEAVKQQDKALEQKGRDLEQKDTALE----QKDKALEPKDKDLEEKDKALEQKDKIP 1450
+ E +++Q+K + ++ + +++ E Q+ + + +++ + E+++ QK+K+
Sbjct: 426 REQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKM- 484
Query: 1451 EEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKA 1510
E++K +Q++ Q++K + ++K EQ++++ Q+EKI E+++K +Q
Sbjct: 485 HEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQ--------- 535
Query: 1511 PEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQ 1570
E+ + E ++ EQ +K EQ+ + QEQ +K+ ++++ EQ+ QK++ EQ +
Sbjct: 536 -EEKIREQEEMMQEQEEKMGEQEEKMQEQ-EKMRRQEEKIREQEEKIREQKEKIREQEEK 593
Query: 1571 ALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQE 1630
E+ + +EQE ++QE ++ KM E++ EK+ EEK++ EK + E+ QE
Sbjct: 594 IWEQEEKIREQEEMMQE---QEEKMWEQE--EKMCEQEEKMQEQEEKMRRQE-EKMWEQE 647
Query: 1631 GRAREQEEKYWRGQD 1645
R R+QEEK Q+
Sbjct: 648 VRLRQQEEKMQEHQE 662
Score = 116 bits (291), Expect = 3e-25
Identities = 111/432 (25%), Positives = 202/432 (46%), Gaps = 67/432 (15%)
Query: 1364 DEVLQQKDKTLEHK-EVVEPKDTAIYQKDEALHVKNEAVK------QQDKALEQKGRDLE 1416
DE L++K+ L+ K ++VE + + I + L K E K Q + G++L+
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 275
Query: 1417 QKDTALE---------------QKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKD 1461
L+ Q++K ++K E ++K EQ++KI E+++K EQ++
Sbjct: 276 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEE 335
Query: 1462 TALEQKDKALEPKDKDLEQKDRVLEQKEKI---------PEEKDKALDQKVRSVEHKAPE 1512
Q++ E ++K Q++ + E++EK+ EEK + L++K+ E K E
Sbjct: 336 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQE-KIRE 394
Query: 1513 DTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQ--KYWALGQKDEALEQNIQ 1570
++ + + +K EQ+ + Q++K+ E++++ EQ K W +++E + + +
Sbjct: 395 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW---RQEEKIHEQEK 451
Query: 1571 ALEENHQTQEQESLVQEDKTR--------KPKMLEEKSPEKVKAMEEKLEALLEKTKALG 1622
EE + +++E QE+K R K KM E+ EK++ EEK+ EK
Sbjct: 452 IREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQ---EKIRKQEEKVWRQEEKMHD-- 506
Query: 1623 LEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRY 1682
QE + REQEEK WR ++ ++E +E +EE EQ+E+ E+ EQ+ +
Sbjct: 507 ------QEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM 560
Query: 1683 -----WRGREDVALEQDTYWRE-----LSCERKVWFPHELDGQGARPHYTEERESTFLDE 1732
R +E+ EQ+ RE E K+W E + E+ E + E
Sbjct: 561 QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIRE-QEEMMQEQEEKMWEQE 619
Query: 1733 GPDDEQEVPLRE 1744
EQE ++E
Sbjct: 620 EKMCEQEEKMQE 631
Score = 98.6 bits (244), Expect = 8e-20
Identities = 62/239 (25%), Positives = 143/239 (59%), Gaps = 22/239 (9%)
Query: 1336 EDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALH 1395
E I+ E+K ++ +++K E ++E+ +QK+K + +E + ++ +++++E +H
Sbjct: 448 EQEKIREEEKRQEQEEMWRQEEKIRE-QEEIWRQKEK-MHEQEKIRKQEEKVWRQEEKMH 505
Query: 1396 VKNEAVKQQDKAL-EQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKD 1454
+ E +++Q++ + Q+ + EQ++ EQ++K E ++ E+++K EQ++K+ +E++
Sbjct: 506 DQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM-QEQE 564
Query: 1455 KALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDT 1514
K Q++ EQ++K E K+K EQ++++ EQ+EKI E+ E+
Sbjct: 565 KMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQ-----------------EEM 607
Query: 1515 VAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALE 1573
+ E +++ EQ +K EQ+ + QEQ++K+ ++++ EQ+ L Q++E ++++ + LE
Sbjct: 608 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV-RLRQQEEKMQEHQEHLE 665
Score = 70.5 bits (171), Expect = 2e-11
Identities = 86/384 (22%), Positives = 172/384 (44%), Gaps = 43/384 (11%)
Query: 311 SKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEK- 369
+K++ + + E + K+ ++EE ++E +E E +++ + E+K +E EK
Sbjct: 279 AKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEW-EEKIQEQEEKIREQEEKIREQEEKM 337
Query: 370 ---------PPEKPAKPERVKTESSEALKA------EKRKLIKDKVGKKHLKEKISKLEE 414
EK + E + E E ++ EK + I++ K H +EKI + EE
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEE 397
Query: 415 KKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKP--DLKPFTPEVR 472
K+ +E+K ++E+++ ++ + ++E+K ++EEK ++ + ++ + + + + E +
Sbjct: 398 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEK 457
Query: 473 KTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGH-RELVLSSPEDL 531
+ + KI I +KE E + Q+ V H +E + E+
Sbjct: 458 RQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEK 517
Query: 532 TQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMK 591
EE RE+ + EQ + + ++ + EE +G++E M+
Sbjct: 518 MWRQEEKIREQEEKIREQEEK-IREQEEMMQEQEE---------------KMGEQEEKMQ 561
Query: 592 EKELVPEVPE---EQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEV 648
E+E + E EQ K R +EEK +E+K RE E + + +EE E
Sbjct: 562 EQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEM---MQEQEEKMWEQ 618
Query: 649 KEDVIEKAE-LEEMEEVHPSDEEE 671
+E + E+ E ++E EE EE+
Sbjct: 619 EEKMCEQEEKMQEQEEKMRRQEEK 642
Score = 69.3 bits (168), Expect = 5e-11
Identities = 79/362 (21%), Positives = 171/362 (47%), Gaps = 38/362 (10%)
Query: 312 KIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEK-- 369
KI+++ + + K+ ++EE++ E ++ R L + + + E+K +E EK
Sbjct: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR-RLEEMMWEKEEKIRELEEKMH 387
Query: 370 PPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEK-KDKEKKEIKKERK 428
EK + E + E + + EKR+ + K+ ++ +EKI + EEK +++EKK ++E K
Sbjct: 388 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ--EEKIREQEEKIREQEKKMWRQEEK 445
Query: 429 ELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVKIDR 488
++++ R+EEK+ ++E R++ K ++ E+ + K +++
Sbjct: 446 IHEQEKIREEEKRQEQEEMWRQEEKIREQE-----------EIWRQKEKMHEQEKIRKQE 494
Query: 489 SRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLAE 548
+ R E+++ + + Q+ + +E + E+ ++ EE RE+ ++ E
Sbjct: 495 EKVWRQEEKMHDQEEKIREQEEKM------WRQEEKIREQEEKIREQEEKIREQEEMMQE 548
Query: 549 QRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPE---EQGS 605
Q + +G++ + E+ ++ + QEE + ++KE + E E EQ
Sbjct: 549 QEEK-MGEQEEKMQEQEK------MRRQEEKIRE--QEEKIREQKEKIREQEEKIWEQEE 599
Query: 606 KDRGLDSGAETEEEKDTW--EEKKQREAERLPDRTEAREESEPEVKEDVIEKAELEEMEE 663
K R + + +EEK W EEK + E++ ++ E E ++ E + + EE +
Sbjct: 600 KIREQEEMMQEQEEK-MWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 658
Query: 664 VH 665
H
Sbjct: 659 EH 660
Score = 54.7 bits (130), Expect = 1e-06
Identities = 93/467 (19%), Positives = 197/467 (42%), Gaps = 35/467 (7%)
Query: 323 LKATTKTAVSKLAKREEVVEEGAKEARSELAKELAK---TEKKAKESSEKPPEKPAKPER 379
L+ ++ K + +EE KE R L+ EL + T+++ KE + K EK E
Sbjct: 177 LEQALSAVATQKKKADRYIEELTKE-RDALSLELYRNTITDEELKEKNAKLQEKLQLVES 235
Query: 380 VKTESSEALKAEKRKLIKDK--VGKKHLKEKISKL--EEKKDKEKKEIKKERKELKKDEG 435
K+E +K KRKL + K + ++ L+ + L E + K + + E EL
Sbjct: 236 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 295
Query: 436 RKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVKIDRSRAIRGE 495
+++E+K ++EEK ++ + ++++ + ++ ++R+ K + + ++ +R +
Sbjct: 296 QQQEEKMWRQEEKIQEWEEKIQE-QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 354
Query: 496 KELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLG 555
+E+ E + + + REL E +E KR+E + EQ
Sbjct: 355 EEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR--Q 412
Query: 556 DKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAE 615
++ + EE + QEE + +++++ E E++ ++ +
Sbjct: 413 EQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREE--EKRQEQEEMWRQEEK 470
Query: 616 TEEEKDTW---------------EEKKQREAERLPDRTEAREESEPEV--KEDVIEKAE- 657
E+++ W EEK R+ E++ D+ E E E ++ +E+ I + E
Sbjct: 471 IREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEE 530
Query: 658 --LEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFGGRELGLQGKAPEKET 715
E+ E++ +E ++ + G ++ MQE K+ + + E + K +E
Sbjct: 531 KIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQ 590
Query: 716 SLFLSSLTTPAGATEHVSYIQDETIPGYSETEQTISDEEIHDEPEER 762
+ E + Q+E + + + E+ EE E EE+
Sbjct: 591 EEKIWEQEEKIREQEEMMQEQEEKM--WEQEEKMCEQEEKMQEQEEK 635
Score = 52.8 bits (125), Expect = 5e-06
Identities = 80/403 (19%), Positives = 180/403 (44%), Gaps = 34/403 (8%)
Query: 309 KPSKIKQRADSKESLKATTKTAVSKLAKREE-----VVEEGAKEARSELAKELAKTEKKA 363
K +K++++ ES K+ + V +L ++ E + ++ + L KEL K
Sbjct: 222 KNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL 281
Query: 364 KESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEI 423
+ E+ R+ + E + ++ K+ + + + +EKI + EEK ++++++
Sbjct: 282 QAQVEENELW----NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 337
Query: 424 KKERKEL--KKDEGRKEEKKDAKKEEKRKDTKPEL----KKISKPDLKPFTPE-VRKTLY 476
+++ + + K+++ R++E+ +KEEK + + + +KI + + K E +R+
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEE 397
Query: 477 KAKVPGRVKIDRSR------AIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPED 530
K + +++ R R E+++ + + Q+ + H + + E+
Sbjct: 398 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE-EE 456
Query: 531 LTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGT---PPSVPGLGQEE 587
Q+ EEM R+E + ++ +K + + Q QEE
Sbjct: 457 KRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEE 516
Query: 588 HVMKEKELVPEVPE---EQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREES 644
+ +++E + E E EQ K R + + +EEK +E+K +E E++ + E E
Sbjct: 517 KMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQ 576
Query: 645 EPEVKEDVIEKAELEEMEEVHPSDEEEEDATKAEGFYQKHMQE 687
E +++E +K ++ E EE E+EE + E Q+ ++
Sbjct: 577 EEKIRE---QKEKIREQEE--KIWEQEEKIREQEEMMQEQEEK 614
Score = 51.2 bits (121), Expect = 1e-05
Identities = 63/343 (18%), Positives = 153/343 (44%), Gaps = 75/343 (21%)
Query: 308 LKPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESS 367
++ + K++ + K + + +K+ ++EE + E ++ R E K++ + E+K E
Sbjct: 392 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR-EQEKKMWRQEEKIHE-Q 449
Query: 368 EKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKER 427
EK E+ + E+ + E E+ ++ + K K H +EKI K EEK ++++++ +
Sbjct: 450 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQK-EKMHEQEKIRKQEEKVWRQEEKMHDQE 508
Query: 428 KELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVKID 487
+++ R++E+K ++EEK ++ + +++ +
Sbjct: 509 EKI-----REQEEKMWRQEEKIREQEEKIR-----------------------------E 534
Query: 488 RSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLA 547
+ IR ++E+ E +E + E+ Q+ E+M+R+E +
Sbjct: 535 QEEKIREQEEMMQE-------------------QEEKMGEQEEKMQEQEKMRRQEEKI-- 573
Query: 548 EQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKD 607
+++ + ++ + EE QEE + +++E++ E E+ ++
Sbjct: 574 REQEEKIREQKEKIREQEE--------------KIWEQEEKIREQEEMMQEQEEKMWEQE 619
Query: 608 RGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVKE 650
+ E EE+ EEK +R+ E++ ++ + E +++E
Sbjct: 620 EKM---CEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 659
Score = 44.3 bits (103), Expect = 0.002
Identities = 28/135 (20%), Positives = 73/135 (54%), Gaps = 7/135 (5%)
Query: 312 KIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPP 371
KI+++ + + + K+ ++EE ++E K R E +++ + E+K +E EK
Sbjct: 531 KIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQE--EKIREQEEKIREQKEKIR 588
Query: 372 EKPAK----PERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKER 427
E+ K E+++ E E ++ ++ K+ + + +EK+ + EEK ++++++ ++
Sbjct: 589 EQEEKIWEQEEKIR-EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 647
Query: 428 KELKKDEGRKEEKKD 442
L++ E + +E ++
Sbjct: 648 VRLRQQEEKMQEHQE 662
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A member
6-like protein 6 [Homo sapiens]
Length = 655
Score = 126 bits (317), Expect = 3e-28
Identities = 95/341 (27%), Positives = 179/341 (52%), Gaps = 41/341 (12%)
Query: 1362 PKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTA 1421
P+ ++ + D+ + + V K A +++E ++ N+ +Q++K Q+ + EQ++
Sbjct: 256 PQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ--QQEEKMWRQEEKIQEQEEKM 313
Query: 1422 LEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQK 1481
EQ+ K E ++K +++K EQ++KI E++DK Q++ EQ++K E ++K Q+
Sbjct: 314 CEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQE 373
Query: 1482 DRVLEQKEKIPEEKDK--ALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQ 1539
+++ EQ EKI E++++ ++K+R E K E K Q+ + +EQ
Sbjct: 374 EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQE---------------KMWRQEKKMREQ 418
Query: 1540 KDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEK 1599
+K+ E++++ Q E+ I+ LEE Q QE++ E+K ++ + ++
Sbjct: 419 DEKIREQEEEMWRQ------------EEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQE 466
Query: 1600 SPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREE 1659
EK++ EEK++ EKT E+ L QE + EQEEK WR ++ + E +EE
Sbjct: 467 QEEKIQRQEEKIQEQEEKT--WRQEKLLKQEEKIWEQEEKMWRQEEKMWE-------QEE 517
Query: 1660 PAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQDTYWREL 1700
EQ+E E+ EQ+ R W+ +E+ EQ+ +EL
Sbjct: 518 KMQEQEEKMQRQEEKMREQEVRLWQ-QEEKMQEQEVRLQEL 557
Score = 117 bits (293), Expect = 2e-25
Identities = 94/382 (24%), Positives = 195/382 (51%), Gaps = 45/382 (11%)
Query: 1316 ILTPDSSFSKSPESLPGPALEDIAIKWEDKVPG--LKDRTSEQKKEP--EPKDEVLQQKD 1371
+L P + L G L+ ++ K + +V L + ++Q++E ++++ +Q++
Sbjct: 253 LLLPQQQLQVEADRL-GKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311
Query: 1372 KTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQ-DKALEQKGRDLEQKDTALEQKDKALE 1430
K E + + ++ +++++E +H + E +++Q DK Q+ + EQ++ EQ++K
Sbjct: 312 KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWR 371
Query: 1431 PKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALE----QKDKALEPKDKDLEQKDRVLE 1486
++K E+ +K EQ++++ +++K EQ++ E Q+ K E +K EQ++ +
Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 1487 QKEKIPEEKDKALDQ--KVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKV- 1543
Q+EKI E ++ DQ K+R VE K E+ +++ EQ +K Q+ + QEQ++K
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEE-----EEKMQEQEEKIQRQEEKIQEQEEKTW 486
Query: 1544 SEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEK 1603
++K E+K W +K E+ + EE Q QE++ QE+K R+ ++ + EK
Sbjct: 487 RQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEK 546
Query: 1604 VKAMEEKLEALLEKTKALGLEESLV-------------------------QEGRAREQEE 1638
++ E +L+ L E+ LG + L+ QE ++ +Q++
Sbjct: 547 MQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQ 606
Query: 1639 KYWRG--QDVVQEWQETSPTRE 1658
++RG Q V +Q+ + +E
Sbjct: 607 DHYRGHLQQYVAAYQQLASGKE 628
Score = 64.3 bits (155), Expect = 2e-09
Identities = 69/353 (19%), Positives = 162/353 (45%), Gaps = 23/353 (6%)
Query: 312 KIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSE-LAKELAKTEKKAK---ESS 367
K++ K ++ K KL + + ++ + + ++ L KEL K + E +
Sbjct: 226 KLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEEN 285
Query: 368 EKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKER 427
E + E E ++ ++ K+ + ++ + +EK+ + EEK +++++I+++
Sbjct: 286 ELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQE 345
Query: 428 KELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVKID 487
++ + E + E+++ +E++ K + E +KI + D K E + K+ + +
Sbjct: 346 DKMWRQEEKIREQEEKIREQEEKMWRQE-EKIREQDEKIQEQEEEMWRQEEKIREQEEKR 404
Query: 488 RSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLA 547
+ + R EK++ + + Q+ + +E + E++ QD EE RE +
Sbjct: 405 QEKMWRQEKKMREQDEKIREQEEEM------WRQEEKIRELEEMMQDQEEKLREVEEKMQ 458
Query: 548 EQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKD 607
E+ + + ++ + EE IQ ++E ++K++E + E E+ ++
Sbjct: 459 EEEEK-MQEQEEKIQRQEE-----KIQEQEEKT---WRQEKLLKQEEKIWEQEEKMWRQE 509
Query: 608 RGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIEKAELEE 660
+ E EE+ EEK QR+ E++ ++ + E +++E + ELEE
Sbjct: 510 EKM---WEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEE 559
Score = 60.1 bits (144), Expect = 3e-08
Identities = 97/468 (20%), Positives = 180/468 (38%), Gaps = 107/468 (22%)
Query: 1425 KDKALEPKDKDLEEKDKALEQKDKI-------PEEKDKALEQKDTALEQKDKALE----- 1472
K L +D DL+ LEQ+ K+ P EK A ++K L + + LE
Sbjct: 21 KSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIA-DEKFFQLSEMEAYLENRKRR 79
Query: 1473 -----PKDKDLEQKDRVLEQKEKIPE-----EKDKALDQKVRSVEHKAPEDTVAEMKDRD 1522
+D DLE+ + + KE + D+A++ S K ++ + K R
Sbjct: 80 GTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQ 139
Query: 1523 LEQTDKAPEQKHQAQEQK-----------------------------------DKVSEKK 1547
+ +K + + +K +K+++++
Sbjct: 140 EKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKER 199
Query: 1548 DQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQ---EDKTRKPKMLEEKSPE-- 1602
D + Y +E E+N + E+ + ++S +Q +D RK + + P+
Sbjct: 200 DAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQ 259
Query: 1603 ----------KVKAMEEKLEALLEKTKALGL--------------------EESLVQEGR 1632
+++++ KL+A +E+ + L E+ QE +
Sbjct: 260 LQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELK 319
Query: 1633 AREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALE 1692
REQEEK WR ++ + E +E +E+ Q+E E+ EQ+ + WR E + E
Sbjct: 320 IREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIR-E 378
Query: 1693 QDTYWRELSCERKVWFPHELDGQGARPHYTEERESTFLDEGPDDEQEVPLREHATRSPWA 1752
QD +E E ++W E R + +E + E EQ+ +RE W
Sbjct: 379 QDEKIQEQ--EEEMWRQEE----KIREQEEKRQEKMWRQEKKMREQDEKIREQ-EEEMWR 431
Query: 1753 SDFK-----DFQESSPQKGLEVERWLAESPVGLPPEEEDKLTRSPFEI 1795
+ K + + +K EVE + E + E+E+K+ R +I
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKM-QEQEEKIQRQEEKI 478
Score = 46.6 bits (109), Expect = 3e-04
Identities = 80/392 (20%), Positives = 170/392 (43%), Gaps = 56/392 (14%)
Query: 337 REEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLI 396
R + +E KE +EL ++L E + E + K ER + L ++ ++
Sbjct: 208 RNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQL----LLPQQQLQVE 263
Query: 397 KDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPEL 456
D++GK+ L+ +KL+ + E+ E+ + ++++ ++E+K ++EEK + +
Sbjct: 264 ADRLGKE-LQSVSAKLQAQV--EENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQE--- 317
Query: 457 KKISKPDLKPFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPT 516
KI + + K + E + + K+ + + R E+++ + + Q+
Sbjct: 318 LKIREQEEKMWRQEEKMHEQEEKI----REQEDKMWRQEEKIREQEEKIREQE-----EK 368
Query: 517 ISGHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGT 576
+ E + E + + EEM R+E + +++ +K +
Sbjct: 369 MWRQEEKIREQDEKIQEQEEEMWRQEEKI--REQEEKRQEKMWR---------------- 410
Query: 577 PPSVPGLGQEEHVMKEKELVPEVPEE---QGSKDRGLDSGAETEEEK-DTWEEKKQREAE 632
QE+ + ++ E + E EE Q K R L+ + +EEK EEK Q E E
Sbjct: 411 --------QEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 633 RLPDRTEAREESEPEVKEDVIEKAELEEM--EEVHPSDEEEEDATKAEGFYQKH--MQEP 688
++ ++ E + E +++E + E++ +E ++EE+ + E +++ MQE
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQ 522
Query: 689 LKVTPRSREAFGGRELGL---QGKAPEKETSL 717
+ R E +E+ L + K E+E L
Sbjct: 523 EEKMQRQEEKMREQEVRLWQQEEKMQEQEVRL 554
Score = 38.5 bits (88), Expect = 0.094
Identities = 29/133 (21%), Positives = 74/133 (55%), Gaps = 5/133 (3%)
Query: 333 KLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEK--PPEKPAKPERVKTESSEALKA 390
K+ + EE++++ ++ R E+ +++ + E+K +E EK E+ + + KT E L
Sbjct: 435 KIRELEEMMQDQEEKLR-EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLK 493
Query: 391 EKRKLIKDKVGKKHLKEKISKLEEK--KDKEKKEIKKERKELKKDEGRKEEKKDAKKEEK 448
++ K+ + + +EK+ + EEK + +EK + ++E+ ++ ++E+K ++E +
Sbjct: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
Query: 449 RKDTKPELKKISK 461
++ + L K+ +
Sbjct: 554 LQELEERLGKLGQ 566
Score = 38.1 bits (87), Expect = 0.12
Identities = 83/387 (21%), Positives = 160/387 (41%), Gaps = 36/387 (9%)
Query: 320 KESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPA-KPE 378
KESLK T T A + V K+ E+ K ++K E + ++ K
Sbjct: 100 KESLKRVTFTLPDDEAIEDAGVSH-VKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKP 158
Query: 379 RVKTESSEALKAEKRKLIKDKVGKKH---LKEKISKLEEKKDKEKKEIKKERKELKKDEG 435
++ A K + L+++ + H + I KL +++D E+ + DE
Sbjct: 159 WLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTIT---DEE 215
Query: 436 RKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVKIDRSRAIRGE 495
KE K+A+ +EK + + E K +++ ++++ L +A++ + + A R
Sbjct: 216 LKE--KNAELQEKLRLVESE-----KSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLG 268
Query: 496 KELSSEPQTPPAQKGTVPL-PTISGHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGL 554
KEL S AQ L ++ +E + E+ Q+ EE E+ + EQ +
Sbjct: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEK-- 326
Query: 555 GDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKDRGLDSGA 614
+ EE + QEE + +++E + E E+ ++ +
Sbjct: 327 ------MWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKI---R 377
Query: 615 ETEEEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIEKAELEEMEEVHPSDEE---- 670
E +E+ EE+ R+ E++ ++ E R+E K EK E+ E++ +EE
Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQE-----KMWRQEKKMREQDEKIREQEEEMWRQ 432
Query: 671 EEDATKAEGFYQKHMQEPLKVTPRSRE 697
EE + E Q ++ +V + +E
Sbjct: 433 EEKIRELEEMMQDQEEKLREVEEKMQE 459
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A member
6-like protein 6 [Homo sapiens]
Length = 655
Score = 126 bits (317), Expect = 3e-28
Identities = 95/341 (27%), Positives = 179/341 (52%), Gaps = 41/341 (12%)
Query: 1362 PKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTA 1421
P+ ++ + D+ + + V K A +++E ++ N+ +Q++K Q+ + EQ++
Sbjct: 256 PQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ--QQEEKMWRQEEKIQEQEEKM 313
Query: 1422 LEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQK 1481
EQ+ K E ++K +++K EQ++KI E++DK Q++ EQ++K E ++K Q+
Sbjct: 314 CEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQE 373
Query: 1482 DRVLEQKEKIPEEKDK--ALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQ 1539
+++ EQ EKI E++++ ++K+R E K E K Q+ + +EQ
Sbjct: 374 EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQE---------------KMWRQEKKMREQ 418
Query: 1540 KDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEK 1599
+K+ E++++ Q E+ I+ LEE Q QE++ E+K ++ + ++
Sbjct: 419 DEKIREQEEEMWRQ------------EEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQE 466
Query: 1600 SPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREE 1659
EK++ EEK++ EKT E+ L QE + EQEEK WR ++ + E +EE
Sbjct: 467 QEEKIQRQEEKIQEQEEKT--WRQEKLLKQEEKIWEQEEKMWRQEEKMWE-------QEE 517
Query: 1660 PAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQDTYWREL 1700
EQ+E E+ EQ+ R W+ +E+ EQ+ +EL
Sbjct: 518 KMQEQEEKMQRQEEKMREQEVRLWQ-QEEKMQEQEVRLQEL 557
Score = 117 bits (293), Expect = 2e-25
Identities = 94/382 (24%), Positives = 195/382 (51%), Gaps = 45/382 (11%)
Query: 1316 ILTPDSSFSKSPESLPGPALEDIAIKWEDKVPG--LKDRTSEQKKEP--EPKDEVLQQKD 1371
+L P + L G L+ ++ K + +V L + ++Q++E ++++ +Q++
Sbjct: 253 LLLPQQQLQVEADRL-GKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311
Query: 1372 KTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQ-DKALEQKGRDLEQKDTALEQKDKALE 1430
K E + + ++ +++++E +H + E +++Q DK Q+ + EQ++ EQ++K
Sbjct: 312 KMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWR 371
Query: 1431 PKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALE----QKDKALEPKDKDLEQKDRVLE 1486
++K E+ +K EQ++++ +++K EQ++ E Q+ K E +K EQ++ +
Sbjct: 372 QEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR 431
Query: 1487 QKEKIPEEKDKALDQ--KVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKV- 1543
Q+EKI E ++ DQ K+R VE K E+ +++ EQ +K Q+ + QEQ++K
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEE-----EEKMQEQEEKIQRQEEKIQEQEEKTW 486
Query: 1544 SEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEK 1603
++K E+K W +K E+ + EE Q QE++ QE+K R+ ++ + EK
Sbjct: 487 RQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEK 546
Query: 1604 VKAMEEKLEALLEKTKALGLEESLV-------------------------QEGRAREQEE 1638
++ E +L+ L E+ LG + L+ QE ++ +Q++
Sbjct: 547 MQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQ 606
Query: 1639 KYWRG--QDVVQEWQETSPTRE 1658
++RG Q V +Q+ + +E
Sbjct: 607 DHYRGHLQQYVAAYQQLASGKE 628
Score = 64.3 bits (155), Expect = 2e-09
Identities = 69/353 (19%), Positives = 162/353 (45%), Gaps = 23/353 (6%)
Query: 312 KIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSE-LAKELAKTEKKAK---ESS 367
K++ K ++ K KL + + ++ + + ++ L KEL K + E +
Sbjct: 226 KLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEEN 285
Query: 368 EKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKER 427
E + E E ++ ++ K+ + ++ + +EK+ + EEK +++++I+++
Sbjct: 286 ELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQE 345
Query: 428 KELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVKID 487
++ + E + E+++ +E++ K + E +KI + D K E + K+ + +
Sbjct: 346 DKMWRQEEKIREQEEKIREQEEKMWRQE-EKIREQDEKIQEQEEEMWRQEEKIREQEEKR 404
Query: 488 RSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLA 547
+ + R EK++ + + Q+ + +E + E++ QD EE RE +
Sbjct: 405 QEKMWRQEKKMREQDEKIREQEEEM------WRQEEKIRELEEMMQDQEEKLREVEEKMQ 458
Query: 548 EQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKD 607
E+ + + ++ + EE IQ ++E ++K++E + E E+ ++
Sbjct: 459 EEEEK-MQEQEEKIQRQEE-----KIQEQEEKT---WRQEKLLKQEEKIWEQEEKMWRQE 509
Query: 608 RGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIEKAELEE 660
+ E EE+ EEK QR+ E++ ++ + E +++E + ELEE
Sbjct: 510 EKM---WEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEE 559
Score = 60.1 bits (144), Expect = 3e-08
Identities = 97/468 (20%), Positives = 180/468 (38%), Gaps = 107/468 (22%)
Query: 1425 KDKALEPKDKDLEEKDKALEQKDKI-------PEEKDKALEQKDTALEQKDKALE----- 1472
K L +D DL+ LEQ+ K+ P EK A ++K L + + LE
Sbjct: 21 KSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIA-DEKFFQLSEMEAYLENRKRR 79
Query: 1473 -----PKDKDLEQKDRVLEQKEKIPE-----EKDKALDQKVRSVEHKAPEDTVAEMKDRD 1522
+D DLE+ + + KE + D+A++ S K ++ + K R
Sbjct: 80 GTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQ 139
Query: 1523 LEQTDKAPEQKHQAQEQK-----------------------------------DKVSEKK 1547
+ +K + + +K +K+++++
Sbjct: 140 EKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKER 199
Query: 1548 DQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQ---EDKTRKPKMLEEKSPE-- 1602
D + Y +E E+N + E+ + ++S +Q +D RK + + P+
Sbjct: 200 DALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQ 259
Query: 1603 ----------KVKAMEEKLEALLEKTKALGL--------------------EESLVQEGR 1632
+++++ KL+A +E+ + L E+ QE +
Sbjct: 260 LQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELK 319
Query: 1633 AREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALE 1692
REQEEK WR ++ + E +E +E+ Q+E E+ EQ+ + WR E + E
Sbjct: 320 IREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIR-E 378
Query: 1693 QDTYWRELSCERKVWFPHELDGQGARPHYTEERESTFLDEGPDDEQEVPLREHATRSPWA 1752
QD +E E ++W E R + +E + E EQ+ +RE W
Sbjct: 379 QDEKIQEQ--EEEMWRQEE----KIREQEEKRQEKMWRQEKKMREQDEKIREQ-EEEMWR 431
Query: 1753 SDFK-----DFQESSPQKGLEVERWLAESPVGLPPEEEDKLTRSPFEI 1795
+ K + + +K EVE + E + E+E+K+ R +I
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKM-QEQEEKIQRQEEKI 478
Score = 47.4 bits (111), Expect = 2e-04
Identities = 87/398 (21%), Positives = 175/398 (43%), Gaps = 56/398 (14%)
Query: 341 VEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEA---LKAEKRKLIK 397
+E+ KE R L+ EL + +E EK E K V++E SE +K KRKL +
Sbjct: 192 IEKLTKE-RDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLER 250
Query: 398 DKV--GKKHLKEKISKL--EEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTK 453
++ ++ L+ + +L E + K + + E EL +++E+K ++EEK ++ +
Sbjct: 251 AQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQE 310
Query: 454 PELKKISKPDLKPFTPEVRKTLYKAKV---PGRVKIDRSRAIRGEKELSSEPQTPPAQKG 510
+K+ + +LK E + + K+ +++ + R E+++ + + Q+
Sbjct: 311 ---EKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQE- 366
Query: 511 TVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPS 570
+ E + E + + EEM R+E + +++ +K +
Sbjct: 367 ----EKMWRQEEKIREQDEKIQEQEEEMWRQEEKI--REQEEKRQEKMWR---------- 410
Query: 571 TAIQGTPPSVPGLGQEEHVMKEKELVPEVPEE---QGSKDRGLDSGAETEEEK-DTWEEK 626
QE+ + ++ E + E EE Q K R L+ + +EEK EEK
Sbjct: 411 --------------QEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEK 456
Query: 627 KQREAERLPDRTEAREESEPEVKEDVIEKAELEEM--EEVHPSDEEEEDATKAEGFYQKH 684
Q E E++ ++ E + E +++E + E++ +E ++EE+ + E +++
Sbjct: 457 MQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQE 516
Query: 685 --MQEPLKVTPRSREAFGGRELGL---QGKAPEKETSL 717
MQE + R E +E+ L + K E+E L
Sbjct: 517 EKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRL 554
Score = 38.5 bits (88), Expect = 0.094
Identities = 29/133 (21%), Positives = 74/133 (55%), Gaps = 5/133 (3%)
Query: 333 KLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEK--PPEKPAKPERVKTESSEALKA 390
K+ + EE++++ ++ R E+ +++ + E+K +E EK E+ + + KT E L
Sbjct: 435 KIRELEEMMQDQEEKLR-EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLK 493
Query: 391 EKRKLIKDKVGKKHLKEKISKLEEK--KDKEKKEIKKERKELKKDEGRKEEKKDAKKEEK 448
++ K+ + + +EK+ + EEK + +EK + ++E+ ++ ++E+K ++E +
Sbjct: 494 QEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVR 553
Query: 449 RKDTKPELKKISK 461
++ + L K+ +
Sbjct: 554 LQELEERLGKLGQ 566
Score = 37.7 bits (86), Expect = 0.16
Identities = 83/385 (21%), Positives = 159/385 (41%), Gaps = 32/385 (8%)
Query: 320 KESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPA-KPE 378
KESLK T T A + V K+ E+ K ++K E + ++ K
Sbjct: 100 KESLKRVTFTLPDDEAIEDAGVSH-VKKNSDEVKSSFKKRQEKMNEKNYTFRKRVVIKKP 158
Query: 379 RVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKER-KELKKDEGRK 437
++ A K + L+++ + H ++ EK KE+ + E + DE K
Sbjct: 159 WLRLGEVTAQKRPENSLLEETLHFDHAV-RMGTYIEKLTKERDALSLELYRNTITDEELK 217
Query: 438 EEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKE 497
E K+A+ +EK + + E K +++ ++++ L +A++ + + A R KE
Sbjct: 218 E--KNAELQEKLRLVESE-----KSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKE 270
Query: 498 LSSEPQTPPAQKGTVPL-PTISGHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGD 556
L S AQ L ++ +E + E+ Q+ EE E+ + EQ +
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEK---- 326
Query: 557 KPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAET 616
+ EE + QEE + +++E + E E+ ++ + E
Sbjct: 327 ----MWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKI---REQ 379
Query: 617 EEEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIEKAELEEMEEVHPSDEE----EE 672
+E+ EE+ R+ E++ ++ E R+E K EK E+ E++ +EE EE
Sbjct: 380 DEKIQEQEEEMWRQEEKIREQEEKRQE-----KMWRQEKKMREQDEKIREQEEEMWRQEE 434
Query: 673 DATKAEGFYQKHMQEPLKVTPRSRE 697
+ E Q ++ +V + +E
Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQE 459
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens]
Length = 436
Score = 120 bits (301), Expect = 2e-26
Identities = 85/365 (23%), Positives = 195/365 (53%), Gaps = 11/365 (3%)
Query: 1349 LKDRTSEQKKEPE----PKDEV---LQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAV 1401
LK++ +E ++E + K E+ +++ + LE ++ P++ + +++ + + V
Sbjct: 9 LKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQV 68
Query: 1402 KQQD-KALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQK 1460
++Q+ + EQ+G+ EQ+ EQ+ + E + + E++ + EQ+ ++ E++ + EQ+
Sbjct: 69 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 128
Query: 1461 DTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKD 1520
EQ+ + E + + EQ+ +V EQ+ ++ E++ + +Q+ + E E V E +
Sbjct: 129 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ---EGQVREQEG 185
Query: 1521 RDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQE 1580
+ EQ + EQ+ Q EQ++++ E+++Q +Q+ Q+++ +Q Q E+ Q Q+
Sbjct: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQK 245
Query: 1581 QESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKY 1640
QE VQ+ + + K E+ ++ + E++ + L +K + E++ QE + REQEE+
Sbjct: 246 QEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQM 305
Query: 1641 WRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQDTYWREL 1700
++ ++E +E +EE G+Q+E ++ EQ + W+ E + +++ ++
Sbjct: 306 REQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQE 365
Query: 1701 SCERK 1705
RK
Sbjct: 366 EQVRK 370
Score = 117 bits (294), Expect = 1e-25
Identities = 79/360 (21%), Positives = 200/360 (55%), Gaps = 11/360 (3%)
Query: 1344 DKVPGLKD-RTSEQKKEP-EPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAV 1401
DK+P ++ + EQ+ + E + +V +Q+ + E + V ++ + +++ + + V
Sbjct: 44 DKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 103
Query: 1402 KQQD-KALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQK 1460
++Q+ + EQ+G+ EQ+ EQ+ + E + + E++ + EQ+ ++ E++ + EQ+
Sbjct: 104 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 163
Query: 1461 DTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAP----EDTVA 1516
EQ+ + E + + EQ+ +V EQ+ ++ E++ + +Q+ + E + E+ +
Sbjct: 164 GQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMG 223
Query: 1517 EMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENH 1576
E +++ +Q ++ EQ+ Q Q+Q+++V ++++Q +Q+ Q+++ EQ Q L++
Sbjct: 224 EQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKE 283
Query: 1577 QTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAR-- 1634
QT+++E ++++ + + EE+ E+ + M E+ E + E+ + +G +E + E + +
Sbjct: 284 QTEQEEQTGEQEEQMREQ--EEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMW 341
Query: 1635 EQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQD 1694
EQ+E+ W+ ++ + E +E +EE +Q+E E+ +Q+ + + E + +++
Sbjct: 342 EQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKE 401
Score = 113 bits (283), Expect = 2e-24
Identities = 80/343 (23%), Positives = 194/343 (56%), Gaps = 13/343 (3%)
Query: 1361 EPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQD-KALEQKGRDLEQKD 1419
E + +V +Q+ + E + V ++ + +++ + + V++Q+ + EQ+G+ EQ+
Sbjct: 91 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 150
Query: 1420 TALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLE 1479
EQ+ + E + + E++ + EQ+ ++ E++ + EQ+ EQ+ + E +++ E
Sbjct: 151 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGE 210
Query: 1480 QKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQ 1539
Q++++ +Q+E++ E++++ Q+ + E E+ V + +++ +Q ++ +Q+ Q +EQ
Sbjct: 211 QEEQMQKQEEQMGEQEEQMRKQEEQMGEQ---EEQVQKQEEQVQKQEEQMRKQEEQMREQ 267
Query: 1540 KDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLV--QEDKTRKPK--- 1594
++++ E+++Q L+QK Q+++ EQ Q E+ Q +EQE + QE++ R+ +
Sbjct: 268 EEQMREQEEQMLKQKEQT-EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQM 326
Query: 1595 -MLEEKSPEKVKAMEEKLEALLEKTKALGLEESLV--QEGRAREQEEKYWRGQDVVQEWQ 1651
EE+ E+ + M E+ E + ++ + +G +E + QE + R+QEE+ + ++ +++ +
Sbjct: 327 GKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQE 386
Query: 1652 ETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQD 1694
E +EE GEQKE ++ EQ+ + +E + +++
Sbjct: 387 EQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEE 429
Score = 113 bits (282), Expect = 3e-24
Identities = 82/356 (23%), Positives = 189/356 (53%), Gaps = 20/356 (5%)
Query: 1352 RTSEQKKEPEPKD-EVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQD-KALE 1409
R E K P P++ +V +Q+ + E + V ++ + +++ + + V++Q+ + E
Sbjct: 39 RKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 98
Query: 1410 QKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDK 1469
Q+G+ EQ+ EQ+ + E + + E++ + EQ+ ++ E++ + EQ+ EQ+ +
Sbjct: 99 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 158
Query: 1470 ALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAP----EDTVAEMKDRDLEQ 1525
E + + EQ+ +V EQ+ ++ E++ + +Q+ + E + E+ + E +++ +Q
Sbjct: 159 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQ 218
Query: 1526 TDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLV 1585
++ EQ+ Q ++Q++++ E+++Q +Q+ Q+++ +Q Q E+ Q +EQE +
Sbjct: 219 EEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQM 278
Query: 1586 QEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRARE-------QEE 1638
+ K + + EE++ E+ + M E+ E + E+ E+ QE + RE QEE
Sbjct: 279 LKQKEQTEQ--EEQTGEQEEQMREQEEQMREQE-----EQMREQEEQMREQEEQMGKQEE 331
Query: 1639 KYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQD 1694
+ W ++ + E +E +EE GEQ+E E+ +Q+ + + E + +++
Sbjct: 332 QMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEE 387
Score = 108 bits (271), Expect = 6e-23
Identities = 75/319 (23%), Positives = 175/319 (54%), Gaps = 25/319 (7%)
Query: 1361 EPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQD-KALEQKGRDLEQKD 1419
E + +V +Q+ + E + V ++ + +++ + + V++Q+ + EQ+G+ EQ+
Sbjct: 140 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEG 199
Query: 1420 TALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLE 1479
EQ+++ E +++ +++++ EQ++++ +++++ EQ++ +Q+++ + +++ +
Sbjct: 200 QMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRK 259
Query: 1480 QKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQ 1539
Q++++ EQ+E++ E++++ L QK E E+ E +++ EQ ++ EQ+ Q +EQ
Sbjct: 260 QEEQMREQEEQMREQEEQMLKQK----EQTEQEEQTGEQEEQMREQEEQMREQEEQMREQ 315
Query: 1540 KDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEK 1599
++++ E+++Q +Q+ QK++ EQ Q ++ Q EQE +Q K
Sbjct: 316 EEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQ------------K 363
Query: 1600 SPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREE 1659
E+V+ EE++ E+ + QE + R+QEE+ ++ + E +E +EE
Sbjct: 364 QEEQVRKQEEQMRKQEEQMRK--------QEEQMRKQEEQMGEQKEQMGEQKEQMREQEE 415
Query: 1660 PAGEQKELAPAWEDTSPEQ 1678
GEQKE E+ EQ
Sbjct: 416 QMGEQKEQMRKQEEHMGEQ 434
Score = 105 bits (261), Expect = 8e-22
Identities = 74/337 (21%), Positives = 184/337 (54%), Gaps = 15/337 (4%)
Query: 1361 EPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQD-KALEQKGRDLEQKD 1419
E + +V +Q+ + E + V ++ + +++ + + V++Q+ + EQ+G+ EQ+
Sbjct: 112 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 171
Query: 1420 TALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLE 1479
EQ+ + E + + E++ + EQ+ ++ E++++ EQ++ +Q+++ E +++ +
Sbjct: 172 QVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRK 231
Query: 1480 QKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQ 1539
Q++++ EQ+E++ +++++ Q+ + + E+ + E +++ EQ ++ +QK Q EQ
Sbjct: 232 QEEQMGEQEEQVQKQEEQVQKQEEQM---RKQEEQMREQEEQMREQEEQMLKQKEQT-EQ 287
Query: 1540 KDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEE- 1598
+++ E+++Q EQ+ Q+++ EQ Q E+ Q +QE + E K + + E+
Sbjct: 288 EEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQM 347
Query: 1599 -KSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTR 1657
K E++ EE+++ E+ + QE + R+QEE+ + ++ +++ +E +
Sbjct: 348 WKQEEQMGEQEEQMQKQEEQVRK--------QEEQMRKQEEQMRKQEEQMRKQEEQMGEQ 399
Query: 1658 EEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQD 1694
+E GEQKE E+ EQ + + E + +++
Sbjct: 400 KEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 93.6 bits (231), Expect = 2e-18
Identities = 54/237 (22%), Positives = 150/237 (63%), Gaps = 6/237 (2%)
Query: 1355 EQKKEPEPKDEVLQQKDKTL-EHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGR 1413
EQ+++ ++E +Q++++ + E +E + ++ + +++E + + E V++Q++ + ++
Sbjct: 203 EQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEE 262
Query: 1414 DL-EQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALE 1472
+ EQ++ EQ+++ L+ K++ E++++ EQ++++ E++++ EQ++ EQ+++ E
Sbjct: 263 QMREQEEQMREQEEQMLKQKEQT-EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMRE 321
Query: 1473 PKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQ 1532
+++ +Q++++ EQKE++ E+K++ Q+ + E E+ + + +++ +Q ++ +Q
Sbjct: 322 QEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQ---EEQMQKQEEQVRKQEEQMRKQ 378
Query: 1533 KHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDK 1589
+ Q ++Q++++ ++++Q EQK QK++ EQ Q E+ Q ++QE + E K
Sbjct: 379 EEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQK 435
Score = 84.3 bits (207), Expect = 1e-15
Identities = 44/213 (20%), Positives = 137/213 (64%), Gaps = 4/213 (1%)
Query: 1343 EDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTL-EHKEVVEPKDTAIYQKDEALHVKNEAV 1401
E+++ +++ EQ+++ + ++E +Q++++ + + +E + ++ + +++E + + E
Sbjct: 226 EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT 285
Query: 1402 KQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKD 1461
+Q+++ EQ+ + EQ++ EQ+++ E +++ E++++ +Q++++ E+K++ EQK+
Sbjct: 286 EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKE 345
Query: 1462 TALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDR 1521
+Q+++ E +++ +Q+++V +Q+E++ +++++ Q+ + + E+ + E K++
Sbjct: 346 QMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQE---EQMRKQEEQMGEQKEQ 402
Query: 1522 DLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQK 1554
EQ ++ EQ+ Q EQK+++ ++++ EQK
Sbjct: 403 MGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQK 435
Score = 79.3 bits (194), Expect = 5e-14
Identities = 40/209 (19%), Positives = 133/209 (63%), Gaps = 4/209 (1%)
Query: 1341 KWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTL-EHKEVVEPKDTAIYQKDEALHVKNE 1399
K E+++ +++ +Q+++ + ++E ++++++ + E +E + ++ + ++ E + +
Sbjct: 231 KQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQ 290
Query: 1400 AVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQ 1459
+Q+++ EQ+ + EQ++ EQ+++ E +++ +++++ EQK+++ E+K++ +Q
Sbjct: 291 TGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQ 350
Query: 1460 KDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMK 1519
++ EQ+++ + +++ +Q++++ +Q+E++ +++++ Q+ + E K + + E K
Sbjct: 351 EEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQK---EQMGEQK 407
Query: 1520 DRDLEQTDKAPEQKHQAQEQKDKVSEKKD 1548
++ EQ ++ EQK Q ++Q++ + E+K+
Sbjct: 408 EQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 57.4 bits (137), Expect = 2e-07
Identities = 75/365 (20%), Positives = 165/365 (45%), Gaps = 30/365 (8%)
Query: 364 KESSEKPPEKPAKPERVKTESSEA---LKAEKRKLIKDKV---GKKHLKEKISKLEEKKD 417
+E EK E + + V+TE SE +K KRKL DK+ + ++E+ ++ E++
Sbjct: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
Query: 418 ---KEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELK-KISKPDLKPFTPEVRK 473
+++ +++++ ++++ EG+ E++ +E++ + + E + + + ++ +VR+
Sbjct: 67 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 126
Query: 474 TLYKAK-VPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLT 532
+ + G+V+ + E ++ + Q+G V +E + E
Sbjct: 127 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV------REQEGQVREQEGQV 180
Query: 533 QDFEEMKREERALLAEQ------RDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQE 586
++ E RE+ + EQ ++ +G++ + EE Q QE
Sbjct: 181 REQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE 240
Query: 587 EHVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWEEK--KQREAERLPDRTEAREES 644
E V K++E V + E+ ++ + E EE+ EE+ KQ+E ++T +EE
Sbjct: 241 EQVQKQEEQVQKQEEQMRKQEEQM---REQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQ 297
Query: 645 EPEVKEDVIEKAELEEMEEVHPSDEEEEDATKAEGFYQ--KHMQEPLKVTPRSREAFGGR 702
E +E + E+ E +E ++EE+ + E ++ + M E + + E G +
Sbjct: 298 MREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQ 357
Query: 703 ELGLQ 707
E +Q
Sbjct: 358 EEQMQ 362
Score = 49.3 bits (116), Expect = 5e-05
Identities = 29/151 (19%), Positives = 83/151 (54%), Gaps = 6/151 (3%)
Query: 314 KQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARS-ELAKELAKTEKKAKESSEK--- 369
+Q + +E ++ + + + + E+ + G +E + E +++ + E++ +E E+
Sbjct: 262 EQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMRE 321
Query: 370 PPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKE 429
E+ K E E E + +K ++ K + +E++ K EE+ K++++++K+ ++
Sbjct: 322 QEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQ 381
Query: 430 LKKDEG--RKEEKKDAKKEEKRKDTKPELKK 458
++K E RK+E++ +++E+ + K ++++
Sbjct: 382 MRKQEEQMRKQEEQMGEQKEQMGEQKEQMRE 412
Score = 47.8 bits (112), Expect = 2e-04
Identities = 55/330 (16%), Positives = 148/330 (44%), Gaps = 53/330 (16%)
Query: 362 KAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKE-KISKLEEKKDKEK 420
+ +E + E + + + E E+ ++++ G+ +E ++ + EE+ +++
Sbjct: 153 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQE 212
Query: 421 KEIKKERKEL--KKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKA 478
++++K+ +++ ++++ RK+E++ ++EE+ + + +++K + ++ ++R+
Sbjct: 213 EQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQK-QEEQMRKQEEQMREQ---- 267
Query: 479 KVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEM 538
+++ + ++ +++ E QT G +E + E+ ++ EE
Sbjct: 268 --EEQMREQEEQMLKQKEQTEQEEQT--------------GEQEEQMREQEEQMREQEEQ 311
Query: 539 KREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPE 598
RE+ + EQ + + EE Q+E + ++KE + +
Sbjct: 312 MREQEEQMREQEEQ--------MGKQEEQMWE--------------QKEQMWEQKEQMWK 349
Query: 599 VPEEQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIE-KAE 657
E+ G ++ + E +++ K++ + + ++ +EE E KE + E K +
Sbjct: 350 QEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQ 409
Query: 658 LEEMEEVHPSDEEEEDATKAEGFYQKHMQE 687
+ E EE E++E K E +HM E
Sbjct: 410 MREQEE--QMGEQKEQMRKQE----EHMGE 433
Score = 44.7 bits (104), Expect = 0.001
Identities = 63/423 (14%), Positives = 171/423 (40%), Gaps = 39/423 (9%)
Query: 285 HLDFLRYPVATQKDLASGAVPTNLKPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEG 344
H+ L+ + T K + +++++ + + ++ ++E V E
Sbjct: 33 HIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 92
Query: 345 AKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKH 404
+ R + + + + +E + E + + + E E+ ++++ G+
Sbjct: 93 EGQVREQ------EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 146
Query: 405 LKEKISKLEEKKDKEKK-EIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPD 463
+E + +E + +E++ +++++ ++++ EG+ E++ +E++ + + E + + +
Sbjct: 147 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEE 206
Query: 464 LKPFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHREL 523
E + + ++ + GE+E + Q QK E
Sbjct: 207 QMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQK----------QEEQ 256
Query: 524 VLSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGL 583
+ E + + E+M+ +E +L ++ T EE Q
Sbjct: 257 MRKQEEQMREQEEQMREQEEQMLKQKEQT----------EQEEQTGEQEEQMREQEEQMR 306
Query: 584 GQEEHVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWEEKKQ---REAERLPDRTEA 640
QEE + +++E + E E+ G ++ + E+K+ E+K+ ++ E++ ++ E
Sbjct: 307 EQEEQMREQEEQMREQEEQMGKQEE------QMWEQKEQMWEQKEQMWKQEEQMGEQEEQ 360
Query: 641 REESEPEVKEDVIEKAELEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFG 700
++ E +V++ ++ ++ + EE EE+ + + QK K R +E
Sbjct: 361 MQKQEEQVRK---QEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQM 417
Query: 701 GRE 703
G +
Sbjct: 418 GEQ 420
Score = 41.2 bits (95), Expect = 0.015
Identities = 45/255 (17%), Positives = 117/255 (45%), Gaps = 29/255 (11%)
Query: 346 KEARSELAKELAKTEKKAKESSE---KPPEKPAKPERVKTESSEALKAEKRKLIKDKVGK 402
+E E +++ K E++ E E K E+ + E + E ++ ++ ++ K +
Sbjct: 205 EEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM 264
Query: 403 KHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKP 462
+ +E++ + EE+ K+K++ ++E + +++E +E+++ +++E++ + E + +
Sbjct: 265 REQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEE 324
Query: 463 DL---KPFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISG 519
+ + E ++ +++ K ++ + GE+E + Q +K
Sbjct: 325 QMGKQEEQMWEQKEQMWEQK----EQMWKQEEQMGEQEEQMQKQEEQVRK---------- 370
Query: 520 HRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPS 579
+E + E+ + EE R++ + EQ++ +G++ + EE Q
Sbjct: 371 -QEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQ-MGEQKEQMREQEEQMGEQKEQMRK-- 426
Query: 580 VPGLGQEEHVMKEKE 594
QEEH+ ++KE
Sbjct: 427 -----QEEHMGEQKE 436
Score = 40.4 bits (93), Expect = 0.025
Identities = 28/128 (21%), Positives = 76/128 (59%), Gaps = 7/128 (5%)
Query: 333 KLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEK 392
++ ++EE + E ++ R E +++ K E++ E E+ E+ K + K E + E+
Sbjct: 304 QMREQEEQMREQEEQMR-EQEEQMGKQEEQMWEQKEQMWEQ--KEQMWKQEEQMGEQEEQ 360
Query: 393 RKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKD--AKKEEKRK 450
+ +++V K+ +E++ K EE+ K++++++K+ +++ + + + E+K+ ++EE+
Sbjct: 361 MQKQEEQVRKQ--EEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMG 418
Query: 451 DTKPELKK 458
+ K +++K
Sbjct: 419 EQKEQMRK 426
Score = 33.1 bits (74), Expect = 4.0
Identities = 47/177 (26%), Positives = 76/177 (42%), Gaps = 28/177 (15%)
Query: 1568 NIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESL 1627
N + E+N + QE+ LV+ +K+ +++ ++L+ LE K L
Sbjct: 6 NEELKEKNAELQEELQLVETEKS------------EIQLHIKELKRKLETDKI-----PL 48
Query: 1628 VQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGRE 1687
QEG+ REQE + + V+E + +E EQ+ E EQ+ + R +E
Sbjct: 49 PQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV-REQE 107
Query: 1688 DVALEQDTYWRELSCERKVWFPHELDGQGARPHYTEERESTFLDEGPDDEQEVPLRE 1744
EQ+ RE + + E +GQ R + RE EG EQE +RE
Sbjct: 108 GQVREQEGQVREQEGQVR-----EQEGQ-VREQEGQVRE----QEGQVREQEGQVRE 154
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 120 bits (301), Expect = 2e-26
Identities = 251/1005 (24%), Positives = 345/1005 (34%), Gaps = 161/1005 (16%)
Query: 1726 ESTFLDEGPDDEQEVPLREHATRSPWASDFKDFQESSPQKGLEVERWLAESPVGLPPEE- 1784
E + L P++ P E + SP ++ S + L + R L ESP+ PPEE
Sbjct: 445 EESPLSPPPEESPTSPPPEASRLSPPP---EELPASPLPEALHLSRPLEESPLSPPPEES 501
Query: 1785 --EDKLTRSPFE-IISPPASPPEMVGQRVPSAPGQESPI-PDPKLMPHMKNEPTTPSWLA 1840
SPF + P SPPE P +P E+P+ P P+ P + P S L+
Sbjct: 502 PLSPPPESSPFSPLEESPLSPPE----ESPPSPALETPLSPPPEASP--LSPPFEESPLS 555
Query: 1841 DIPPWVPKDRPLPPAPLSPAP--GPPTPAPESHTPAPFSWGTAEYDSVVAAVQEG--AAE 1896
P +P P + LSP P P +P PE +P E + +E +
Sbjct: 556 PPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSP----PPEASRLFPPFEESPLSPP 611
Query: 1897 LEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEASK-------SHATTEPEQ- 1948
E P SP + R + E+ P + S S PE S+ S + PE+
Sbjct: 612 PEESPLSPPPEASRLS--PPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEES 669
Query: 1949 --TEPEQREPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAA 2006
+ P + PT P E S L+ PT PP + PP S
Sbjct: 670 PLSPPPEESPTSPPPEAS----------RLSPPPEDSPTSPPPEDSPASPPPEDSLMSLP 719
Query: 2007 AGRNTSAEKELSSPISPKSLQSDTPTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRA 2066
+ + P+S GP + PRPE P + P P + P+A
Sbjct: 720 LEESPLLPLPEEPQLCPRS-------------EGPHLSPRPEE-PHLSPRPEEPHLSPQA 765
Query: 2067 --PILSKGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEKGAREQ-----PE 2119
P LS P P L P+ SP+ G H + L E PE
Sbjct: 766 EEPHLSPQPEEP----CLCAVPEEPHLSPQAEG-PHLSPQPEELHLSPQTEEPHLSPVPE 820
Query: 2120 KEAQSPSP--PHPIPMG-SPTLWPE-TEAHVSPPLDSHLGPARPSLDFPASAFGFSSLQP 2175
+ SP P H P P L P E+H+SP L+ P P + P G
Sbjct: 821 EPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEK--PPLSPRPEKPPEEPGQCPAPE 878
Query: 2176 APPQLPSPAEPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEVTKAPSLDSSL-PQLP 2234
P P P EP +P G+ AL+ PG P + E E+ +PS + SL PQL
Sbjct: 879 ELPLFPPPGEPSLSP-----LLGEPALS-EPGEPPLSPLPE--ELPLSPSGEPSLSPQLM 930
Query: 2235 SPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFSPSLEAAEQESGELDPGME 2294
P LP P SP + + A P +S + E LE G+ DP
Sbjct: 931 PPDP--------LPPPLSPII-----TAAAPPALSPLGE-----LEYPFGAKGDSDPESP 972
Query: 2295 PAAHSLWDLTPLSPAPPASL-------DLALAPAPSLPGDMGDGIL--PCHLECSEAATE 2345
AA L TP+SP P A+ + L P+P P IL P +CS
Sbjct: 973 LAAPIL--ETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQH 1030
Query: 2346 KPSPFQVPSEDCAANGPTETSPNPPGPA-------------PAKAENEEAAACPAWERGA 2392
P P C+ + P+P P + E CPA E A
Sbjct: 1031 SLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSA 1090
Query: 2393 WPEGAERSSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSF 2452
S D P G +P G EP G L+
Sbjct: 1091 --TSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASEL 1148
Query: 2453 LNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPPTSASDSGSSQSD 2512
P+ +D +L+ V ++ G G PC +E P + + +
Sbjct: 1149 KGSPV--LLDPEELAPVTPMEVYPECKQTAG----QGSPCEEQEE-PRAPVAPTPPTLIK 1201
Query: 2513 SDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDP---- 2568
SD+ E A A+ E P D GG S + D P
Sbjct: 1202 SDIVNEISNLSQGDASASFPGSEPLLGSP-DPEGGGSLSMELGVSTDVSPARDEGSLRLC 1260
Query: 2569 RPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASPARRLDLRGKR 2628
S P D + G + G K +G GRR +SPAR +G+
Sbjct: 1261 TDSLPETDDSLLCDAGTAISGG---------KAEGEKGRRR------SSPARSRIKQGRS 1305
Query: 2629 SPTPGK-----GPADRASRAPPRPRSTTSQVTPAEEKDGHSPMSK 2668
S PG+ G R R +ST S + D S SK
Sbjct: 1306 SSFPGRRRPRGGAHGGRGRGRARLKSTASSIETLVVADIDSSPSK 1350
Score = 107 bits (266), Expect = 2e-22
Identities = 225/896 (25%), Positives = 308/896 (34%), Gaps = 129/896 (14%)
Query: 1749 SPWASDFKDFQESSPQKGLEVERWLAESPVGL-----PPEEEDKLTRSPFEIISPPASPP 1803
S W ++ +G + R +AE + PPE D T P + P
Sbjct: 337 SEWFENYSLCHRCHKAQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQP 396
Query: 1804 E--MVGQRVPSAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSPAP 1861
+ V P PG P ++ EP + L + P +P P +PLSP
Sbjct: 397 KGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLP---PPEESPLSP-- 451
Query: 1862 GPPTPAPESHTPAPFSWGTAEYDSVVAAVQEG---AAELEGGPYSPLGKDYRKAEGEREE 1918
PP +P S P + + + E + LE P SP E
Sbjct: 452 -PPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSP-----------PPE 499
Query: 1919 EGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPTPY-PDERSFQYADIYEQMMLT 1977
E P +SS S + E+ S PE++ P TP P + + +E+ L+
Sbjct: 500 ESPLSPPPESSPFSPLEESPLS----PPEESPPSPALETPLSPPPEASPLSPPFEESPLS 555
Query: 1978 GLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDTPTFSYAA 2037
PT PP + PP E + E +S P L P F +
Sbjct: 556 PPPEELPTSPPPEASRLSPPP-----EESPMSPPPEESPMSPPPEASRL---FPPFEESP 607
Query: 2038 LAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGP-SPPLNGNILSCSP--DRRSPSPK 2094
L+ P P P PP P +P + P SPP + LS P R SP P+
Sbjct: 608 LSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPE 667
Query: 2095 ESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSH- 2153
ES S + + S + +R P E SPP P SP P ++ +S PL+
Sbjct: 668 ESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPP---PEDSPASPPPEDSLMSLPLEESP 724
Query: 2154 --LGPARPSLDFPASAFGFSSLQPAPPQL-PSPAEPRSAPCGSLAFSG----DRALALAP 2206
P P L P S S +P P L P P EP +P + L P
Sbjct: 725 LLPLPEEPQL-CPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVP 783
Query: 2207 GPPTRTRHDEYLEVTKAPSLDSSLPQLPSP---SSPGAPLLSNLPRPASPALSEGSSSEA 2263
P + E ++ P PQ P P P LS P+P LS S
Sbjct: 784 EEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLS--PQPEESHLSPQSEEPC 841
Query: 2264 TTPVISSVAERFSPSLE----AAEQESGELDPGMEPAAHSLWDLTPLSPAP--PASLDLA 2317
+P SP LE + E +PG PA L PL P P P+ L
Sbjct: 842 LSP--RPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEEL----PLFPPPGEPSLSPLL 895
Query: 2318 LAPAPSLPGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKA 2377
PA S PG+ LP L S + SP +P + P PP +P
Sbjct: 896 GEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPD-----------PLPPPLSPIIT 944
Query: 2378 ENEEAAACPAWERGAWPEGAERSSRPDTLLSP---EQPVCPAGGSGG-----------PP 2423
A P E +P GA+ S P++ L+ E P+ P + PP
Sbjct: 945 AAAPPALSPLGEL-EYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPP 1003
Query: 2424 SSASPEVEAGPQGCATEPRPHR-----------GELSPSFLNPPLPPSIDDRDLSTEEVR 2472
S SP A P EP P + PS +PP P LS +
Sbjct: 1004 SPGSPVGPASP--ILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIG-K 1060
Query: 2473 LVGRGGRRRVGGPGTTGGPCPVTDETPPTSASDSGSSQSDSDVPPETEECPSITAEAALD 2532
+VG + T P P++ S S D CP+ + ALD
Sbjct: 1061 VVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDL-------SCPAPSPAPALD 1113
Query: 2533 --SDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRPDVCMADPEGLS 2586
S D P+D G+ PG P P P S + + DPE L+
Sbjct: 1114 DFSGLGEDTAPLD---GIDA-----PGSQPEPGQTPGSLASELKGSPVLLDPEELA 1161
Score = 99.8 bits (247), Expect = 3e-20
Identities = 175/655 (26%), Positives = 227/655 (34%), Gaps = 119/655 (18%)
Query: 2041 PTVPPRPEPGPSMEPSLTPPAVPPRAPILS----KGPSPPLNGNILSCSP---DRRSPSP 2093
P +PP E S P +P + PP A LS + P+ PL + P SP P
Sbjct: 439 PLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPP 498
Query: 2094 KESGRSHWDDSTSDSELEKGAREQPEKEAQSP---SPPHPIPMGSPTLWPETEAHVSPPL 2150
+ES S +S+ S LE+ PE+ SP +P P P SP P E+ +SPP
Sbjct: 499 EESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPP 558
Query: 2151 DSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPC-----GSLAFSGDRALALA 2205
+ P P P A S L P P + P P +P S F L+
Sbjct: 559 EEL--PTSP----PPEA---SRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLS 609
Query: 2206 PGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATT 2265
P P E +P ++S P SP +P P P +S S
Sbjct: 610 PPPE---------ESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLS----PL 656
Query: 2266 PVISSVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAPAPSLP 2325
PV+S R SP E L P E +P SP P AS L+P P
Sbjct: 657 PVVS----RLSP-----PPEESPLSPPPEE--------SPTSPPPEAS---RLSPPPE-- 694
Query: 2326 GDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAAC 2385
+ + + SP P ED + P E SP P P EE C
Sbjct: 695 ------------DSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLP-------EEPQLC 735
Query: 2386 PAWE---------------RGAWPEGAERSSRPDTLLSPEQPVCPAGGSGGP---PSSAS 2427
P E R P + ++ P PE+P C P P +
Sbjct: 736 PRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEP-CLCAVPEEPHLSPQAEG 794
Query: 2428 PEVEAGPQGCATEPRPHRGELSPSFLNPPLPPSIDDRDLS--TEEVRLVGRGGRRRVGGP 2485
P + P+ P+ LSP P L P ++ LS +EE L R + P
Sbjct: 795 PHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHL-SP 853
Query: 2486 GTTGGPCPVTDETPPTSASDSGSSQSDSDVPPETEECPS-ITAEAALDSDEDGDFLPVDK 2544
P E PP + + PP E S + E AL + P+ +
Sbjct: 854 ELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPE 913
Query: 2545 AGGVSGTHHPRPGHDPPPLPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGR 2604
+S + P P L PDP P P P + A P LS L E E G
Sbjct: 914 ELPLSPSGEPSLS---PQLMPPDPLPPPLSPIITAAAPPALSP-------LGELEYPFG- 962
Query: 2605 VGRRAPGKAKPASPARRLDLRGKRSPTPGKGPADRASRAPPR--PRSTTSQVTPA 2657
A G + P SP L SP P D PP P S S V PA
Sbjct: 963 ----AKGDSDPESPLAAPILETPISPPPEANCTD-PEPVPPMILPPSPGSPVGPA 1012
Score = 68.9 bits (167), Expect = 7e-11
Identities = 135/557 (24%), Positives = 194/557 (34%), Gaps = 104/557 (18%)
Query: 1776 SPVGLPPEEEDKLTRSPFEIISPPASPPEMVGQRVPSAPGQESPIPDP-KLMPHMKNEPT 1834
+P GL D + P + P SP E+ + P P Q P DP L P EP
Sbjct: 2131 TPAGLSTSA-DGFLKPPAGSVPGPDSPGELFLKLPPQVPAQ-VPSQDPFGLAPAYPLEPR 2188
Query: 1835 TPSWLADIPPW-----VPKDRPLPPAPLSPAPGPP---------TPAPESHTPAPF-SWG 1879
P+ PP+ P P+ A P G P TP + TP PF
Sbjct: 2189 FPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPR 2248
Query: 1880 TAEYDSVVAAVQEGAAELEGGPYS-------PLGKDYRKAEGEREEEGRA---------- 1922
D++ G GG S P G+ + E ++EE G +
Sbjct: 2249 CPSLDNLAVPESPGVG---GGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLG 2305
Query: 1923 --EAPDKSSH----SSKVPEASKSHATTEPEQTEPEQ-------REPTP----------Y 1959
++P +H K P+ K+ T Q EP+ +EP P +
Sbjct: 2306 FVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSH 2365
Query: 1960 PD-ERSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCL-STKEAAAGRNTSAEKEL 2017
PD R Y D Y Q LT P PP P L S + + ++
Sbjct: 2366 PDIFRPGSYTDPYAQPPLT----PRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSS 2421
Query: 2018 SSPISPKSLQSDTPTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPI-LSKGPSPP 2076
SP++P+ L ++ A P P P P P P + P AP+ P PP
Sbjct: 2422 QSPLTPRPLSAE------AFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPP 2475
Query: 2077 ----LNGNILSCSPDRRS-PSPKESGRSHWDDSTSDSELEKGAREQPEKEA--QSPSP-- 2127
G++ S P+ +G + + S P A +PSP
Sbjct: 2476 EVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMR 2535
Query: 2128 -PHPIPMGSPTLWPETEAHVSPP---LDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSP 2183
P +G P+L P PP ++SH GP P+L P S ++ A
Sbjct: 2536 FTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPG-PTLGKPQS----TNYTVATGNF--- 2587
Query: 2184 AEPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPL 2243
P +P G + S + L+P P V P+ D SLP L +S + +
Sbjct: 2588 -HPSGSPLGPSSGSTGESYGLSPLRPP--------SVLPPPAPDGSLPYLSHGASQRSGI 2638
Query: 2244 LSNLPRPASPALSEGSS 2260
S + + P GSS
Sbjct: 2639 TSPVEKREDPGTGMGSS 2655
Score = 57.0 bits (136), Expect = 3e-07
Identities = 130/529 (24%), Positives = 176/529 (33%), Gaps = 119/529 (22%)
Query: 2115 REQPEKEAQSPSPPHPIP---MGSPT----LWPETEAHVSPPLDSHLGPARPSLDF---- 2163
R P+ A PP P +GSPT L + + PP S GP P F
Sbjct: 2105 RIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLP 2164
Query: 2164 ---PASA-----FGFSSLQP-------APPQLPSPAEPRSAPCGS-LAFSGDRALALAPG 2207
PA FG + P APP P P AP + + R A PG
Sbjct: 2165 PQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPG 2224
Query: 2208 -----PPTRTRHDEYLEVTKAPSLDSSLPQLPSPS-SPGAPLLSNLPRPASPALSEGSSS 2261
PP RH P P P P P L NL P SP + G +S
Sbjct: 2225 EFHTTPPGTPRHQ---------------PSTPDPFLKPRCPSLDNLAVPESPGVGGGKAS 2269
Query: 2262 EATTPVISSVAERFS-PSLEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAP 2320
E P++S S +LE ++E G P S PP +L
Sbjct: 2270 E---PLLSPPPFGESRKALEVKKEELGASSP---------------SYGPP---NLGFVD 2308
Query: 2321 APSLPGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANGPTETSPNPPG-------PA 2373
+PS +G L + P F+ P A+ + P PG P
Sbjct: 2309 SPSSGTHLGGLEL-----------KTPDVFKAPLTPRAS----QVEPQSPGLGLRPQEPP 2353
Query: 2374 PAKAENEEAAACPAWERGAWPEGAERSSRPDTLLSPE-QPVCPAGGSGGPPSS------- 2425
PA+A A P + G+ L+P QP P PP S
Sbjct: 2354 PAQA----LAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFS 2409
Query: 2426 ---ASPEVEAGPQGCATEPRPHRGELSPSFLNPPLPPSIDDRD-LSTEEVRLVGRGGRRR 2481
ASP+ ++ Q T PRP E +F P+ P D S R R
Sbjct: 2410 RVPASPQSQSSSQSPLT-PRPLSAE---AFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAP 2465
Query: 2482 VGGPGTTGGPCPVTDETPPTSASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLP 2541
+ P P P E + S + +S P P+ A + S + +F+
Sbjct: 2466 LHKP-----PRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVR 2520
Query: 2542 VDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRPDVCMADPEGLSSESG 2590
G GT P P + +P +P P+P + P G++S G
Sbjct: 2521 SPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPG--LPPPHGINSHFG 2567
Score = 56.2 bits (134), Expect = 4e-07
Identities = 116/444 (26%), Positives = 151/444 (34%), Gaps = 96/444 (21%)
Query: 2259 SSSEATTPVISSVAERFSPSLEAAEQESGELDP------GMEPAAHSLWDLTPLSPAPPA 2312
S +E TPV S RFSP E + + E D G H +T + P P
Sbjct: 360 SVAEQHTPVCS----RFSPP-EPGDTPTDEPDALYVACQGQPKGGH----VTSMQPKEPG 410
Query: 2313 SLDLALAPAPSLPGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGP 2372
L P G G + P EA + P P E+ + P E SP P P
Sbjct: 411 PLQCEAKPL----GKAGVQLEPQ----LEAPLNEEMPLLPPPEESPLSPPPEESPTSPPP 462
Query: 2373 APAKAE--NEEAAACPAWERGAWPEGAERSSRP--DTLLSP---EQPVCPAGGSGG---- 2421
++ EE A P E A SRP ++ LSP E P+ P S
Sbjct: 463 EASRLSPPPEELPASPLPE-------ALHLSRPLEESPLSPPPEESPLSPPPESSPFSPL 515
Query: 2422 PPSSASPEVEAGPQGC---ATEPRPHRGELSPSFLNPPLPPSIDDRDLSTEEVRLVGRGG 2478
S SP E+ P P P LSP F PL P EE+
Sbjct: 516 EESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSP-------PPEELPTSPPPE 568
Query: 2479 RRRVGGPGTTGGPCPVTDE---TPPTSASDSGSSQSDSDVPPETEECPSITAEAALDSDE 2535
R+ P P +E +PP AS +S + P EE P
Sbjct: 569 ASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESP------------ 616
Query: 2536 DGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRPDVCMADPEGLSSESGRVERL 2595
P +A +S P D P P P+ P P P+V P + S R+
Sbjct: 617 ---LSPPPEASRLS-----PPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVS---RLSPP 665
Query: 2596 REKEKVQGRVGRRAPGKAKPASP---ARRLDLRGKRSPTPGKGPADRASRAPPRPRST-- 2650
E+ + P + P SP A RL + SPT P S A P P +
Sbjct: 666 PEESPLS------PPPEESPTSPPPEASRLSPPPEDSPT---SPPPEDSPASPPPEDSLM 716
Query: 2651 -----TSQVTPAEEKDGHSPMSKG 2669
S + P E+ P S+G
Sbjct: 717 SLPLEESPLLPLPEEPQLCPRSEG 740
Score = 55.8 bits (133), Expect = 6e-07
Identities = 110/427 (25%), Positives = 147/427 (34%), Gaps = 102/427 (23%)
Query: 2307 SPAPPASLDLAL-----APAPSLPGDMGDGILPCHLECSEAATEKPSPFQVPSED----- 2356
SP PA L + PA S+PG G L L P QVPS+D
Sbjct: 2128 SPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLP-------PQVPAQVPSQDPFGLA 2180
Query: 2357 ----CAANGPTETSPNPPGPAPAKAENEEAAACPAWERGAW--------PEGAERS--SR 2402
PT PP P+P A + + GA P G R S
Sbjct: 2181 PAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPST 2240
Query: 2403 PDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPPLPPSID 2462
PD L P CP+ + P S P V G A+EP LSP PP S
Sbjct: 2241 PDPFLKPR---CPSLDNLAVPES--PGVGGGK---ASEPL-----LSP----PPFGESRK 2283
Query: 2463 DRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPPTSASDSGSSQSDSDVPPETEEC 2522
++ EE+ G + GP + P+S + G + + P+ +
Sbjct: 2284 ALEVKKEEL-----------GASSPSYGPPNLGFVDSPSSGTHLGGLELKT---PDVFKA 2329
Query: 2523 PSITAEAALDSDEDGDFL-----PVDKAGGVSGTHHP---RPGHDPPPLPQPD--PRPSP 2572
P + ++ G L P +A S HP RPG P QP PRP P
Sbjct: 2330 PLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQP 2389
Query: 2573 PRPDVCMA-DPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASPARRLDLRGKRSPT 2631
P P+ C A P L S+ P PASP + + +P
Sbjct: 2390 PPPESCCALPPRSLPSD---------------------PFSRVPASPQSQSSSQSPLTPR 2428
Query: 2632 PGKGPADRASRAPPRPRSTTSQVTP---AEEKDGHSPMSK-----GLVNGLKAGPMALSS 2683
P A S PR +S P + +D +P+ K KAG +A +S
Sbjct: 2429 PLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTS 2488
Query: 2684 KGSSGAP 2690
G+ G P
Sbjct: 2489 LGAGGFP 2495
Score = 53.1 bits (126), Expect = 4e-06
Identities = 208/858 (24%), Positives = 277/858 (32%), Gaps = 192/858 (22%)
Query: 1798 PPASPPEMVGQRVPSAPGQESPIPDPKLMPHMKNE-----PTTPSWLADIPPWVPKDRPL 1852
PP S P RVP++P +S P + E P TP + + P P RP
Sbjct: 2399 PPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQ 2458
Query: 1853 PPAPLSPAPGPPTPAPE---------SHT-------PAPFSWGTA-EYDSVVAAVQ---- 1891
P +P PP P P +HT PA G A E + V + Q
Sbjct: 2459 SRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNF 2518
Query: 1892 ---EGAAELEGGPYSPLGKDYRKAEGERE------EEGRAEAPDKSSHSSKVPEASKSHA 1942
G G P SP+ + +A GE + G +SH P K +
Sbjct: 2519 VRSPGTGAFVGTP-SPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQS 2577
Query: 1943 TTEPEQT--------------------------EPEQREPTPYPD-----------ERSF 1965
T T P P P PD +RS
Sbjct: 2578 TNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSG 2637
Query: 1966 QYADIYE-QMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKEL--SSPIS 2022
+ + + + TG+G + T E P G LS E R +EL I
Sbjct: 2638 ITSPVEKREDPGTGMGSSLATAELP-GTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQ 2696
Query: 2023 PKSLQSDTPTFSYAALAGPTVPP---RPEP-GPSMEP---SLTPPAVPPRAPILSKGPSP 2075
+L+ + T AA AG PP EP P+ E TP A L P
Sbjct: 2697 RNTLRQEKET--AAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPS 2754
Query: 2076 PLNGNILS----CSPDRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPH-P 2130
L+G IL S DR S P + S D + +L G++ ++ +P P P
Sbjct: 2755 KLSGPILGPGSFPSDDRLSRPPPPATPSSMD--VNSRQLVGGSQAFYQR---APYPGSLP 2809
Query: 2131 IPMGSPTLWPETEAHVSPPLDSHLG---PARPSLDFPASAFGFSSLQPAPPQLPSPAEPR 2187
+ LW + +A + + + P+ P + A G S L +LP P EP
Sbjct: 2810 LQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALG-SPLAGISTRLPGPGEPV 2868
Query: 2188 SAPCGSLAFSGDR---ALALAP--------GPPTRTR--------HDEYLEVTKAPSLDS 2228
P G F R L P GPP R R H E + ++
Sbjct: 2869 PGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSG 2928
Query: 2229 SLPQLPSPSSPGAPLLSN----LPRPASPALSEGSSSEATTPVISSVAERFSPSLEAAEQ 2284
PQ PS+P AP L+N P P L G P + + +LEA +
Sbjct: 2929 LPPQ--KPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKL 2986
Query: 2285 --ESGELDPGM---------EPAAH------------SLWDLTPLSPAPP--------AS 2313
E ELD E AH L L L P
Sbjct: 2987 PCEDPELDDDFDAHKALEDDEELAHLGLGVDVAKGDDELGTLENLETNDPHLDDLLNGDE 3046
Query: 2314 LDLALAPAPSLPGDMGD--GILPCHLECSEAATEKPSPFQVPSEDCAANGPTETSPNPPG 2371
DL P L D GD I HL E+A EK + GP PP
Sbjct: 3047 FDLLAYTDPEL--DTGDKKDIFNEHLRLVESANEKAEREALLRG--VEPGPLGPEERPP- 3101
Query: 2372 PAPAKAENEEAAACPAWERGAWPEGAERSSRPDTLLSPEQPVCPAGGS------------ 2419
PA +E A+ P + G S T+ +P+ PA S
Sbjct: 3102 PAADASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPAANSLGLGLKPGQSMM 3161
Query: 2420 --------GGPPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPPLPPSIDDRDLSTEEV 2471
GP SS+ E G P H L+PS L+ P S+ E+
Sbjct: 3162 GSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHL--LTPSPLSGPGGSSL------LEKF 3213
Query: 2472 RLVGRGGRRRVGGPGTTG 2489
L G GGP +G
Sbjct: 3214 ELES-GALTLPGGPAASG 3230
Score = 45.1 bits (105), Expect = 0.001
Identities = 167/699 (23%), Positives = 225/699 (32%), Gaps = 148/699 (21%)
Query: 560 PLDTAEEGPPSTAIQ---GTPPSVPGLG---QEEHVMKEKELVPEVPEEQGSKDRGLDSG 613
PL EE PPS A++ PP L +E + E +P P + S+ L
Sbjct: 519 PLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASR---LSPP 575
Query: 614 AETEEEKDTWEEKKQR---EAERLPDRTEAREESEPEVKEDVIEKAELEEMEEVHPSDEE 670
E EE EA RL E S P E++ L E
Sbjct: 576 PEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPP------EESPLSPPPEASRLSPP 629
Query: 671 EEDATKAEGFYQKHMQEPLKVTPRSREAFGGRELGLQGKAPEKETSLFLSSLTTPAGATE 730
ED+ + + M P +V+ S R P +E+ L +P
Sbjct: 630 PEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRL-----SPPPEESPLSPPPEESPTSPP- 683
Query: 731 HVSYIQDETIPGYSETEQTISDEEIHDEPEERPAPPRFHTSTYDLPGPEGAGPFEASQPA 790
P S D PE+ PA P S LP E P
Sbjct: 684 ----------PEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEE--SPLLPLPEE 731
Query: 791 DSAVPATSGKVYGTPETELTY----PTNIVAAPLAEEEHVS------SATSITECDKLSS 840
P + G + +P E + P +P AEE H+S ++ E LS
Sbjct: 732 PQLCPRSEGP-HLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSP 790
Query: 841 FATSVAEDQSVASL-TAPQTEETGKSSLLLDTVTSIPSSRTEATQGLDYVPSAGTISPTS 899
A L +PQTEE ++ +P + Q P +SP S
Sbjct: 791 QAEGPHLSPQPEELHLSPQTEE--------PHLSPVPEEPCLSPQ-----PEESHLSPQS 837
Query: 900 SLEEDKGFKSPPCEDFSVTGESEKRGEIIGKGLSGERAVEEEEEETANVEMSEKLCSQYG 959
++ SP E+ ++ E EK LS E+ EE E+L
Sbjct: 838 ----EEPCLSPRPEESHLSPELEK------PPLSPR--PEKPPEEPGQCPAPEEL----- 880
Query: 960 TPVFSAPGH-ALHP--GEPALGEAEERCLSPDDSTVKMAS----------------PPPS 1000
P+F PG +L P GEPAL E E LSP + ++ PPP
Sbjct: 881 -PLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPL 939
Query: 1001 GPPSATHTPFHQSPVEEKSEPQDFQEADSWGDTKRTPGVGKEDAAEETVKPGPEEGTLEK 1060
P P SP+ E P + DS ++ + E + P PE +
Sbjct: 940 SPIITAAAPPALSPLGELEYPFG-AKGDSDPESPLAAPI-----LETPISPPPEANCTD- 992
Query: 1061 EEKVPPPRSPQAQEAPVNIDEGLTGCTIQLLPAQDKAIVFEIMEAGEPTGPILGAEALPG 1120
E VPP P + +PV P PIL E LP
Sbjct: 993 PEPVPPMILPPSPGSPVG-----------------------------PASPIL-MEPLPP 1022
Query: 1121 GLRTLPQEPGKPQKDEVLRYPDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQY 1180
L Q PQ P SP LSVPSP P K E
Sbjct: 1023 QCSPLLQHSLVPQNS-----PPSQCSPPALP----LSVPSP----LSPIGKVVGVSDEAE 1069
Query: 1181 LHKDRWPEVSPEDTQSLSLSEESPSKETSLDVSSKQLSP 1219
LH+ +VS + +L S SP D+S SP
Sbjct: 1070 LHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSP 1108
Score = 41.2 bits (95), Expect = 0.015
Identities = 55/214 (25%), Positives = 78/214 (36%), Gaps = 31/214 (14%)
Query: 1063 KVPPPRSPQAQEAPVNIDEGLTGCTIQL--LPAQDKAIVFEIMEAGEPTGPILGAEALPG 1120
+ PP + P Q +P+ +GL GC QL P + E+ P GP A PG
Sbjct: 4239 QTPPYQEPGTQTSPL---QGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPR-LPAPPG 4294
Query: 1121 GLRT-----------LPQEPGKPQKDEVLRYPDRSLSPEDAESLSVLSVPSPDTANQEPT 1169
L T P P +P++ L P L E + P P EP
Sbjct: 4295 ALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPP 4354
Query: 1170 P--KSPCG--LTEQYLHKDRWPEVSPEDTQSLSLSEESPSKETSLDVSSKQLSPES--LG 1223
P SP L + K P P++ E+S LD + Q+ PE+ L
Sbjct: 4355 PGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLS 4414
Query: 1224 TLQ--------FGELNLGKEEMGHLMQAEDTSHH 1249
Q G ++ +E G + A TS+H
Sbjct: 4415 IKQEPREEPCALGAQSVKREANGEPIGAPGTSNH 4448
Score = 40.4 bits (93), Expect = 0.025
Identities = 101/476 (21%), Positives = 172/476 (36%), Gaps = 94/476 (19%)
Query: 397 KDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPEL 456
+D +K L K ++++ D+ + RK+L+K++G + + K+ ++ P
Sbjct: 4510 EDAAARKPLTPKPKRVQKASDR----LVSSRKKLRKEDGVRASEALLKQLKQELSLLPLT 4565
Query: 457 KKISKPDLKPFTP-----------EVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTP 505
+ + F P ++R +P D + + LS+ P TP
Sbjct: 4566 EPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALP--TGPDYYSQLLTKNNLSNPP-TP 4622
Query: 506 PAQKGTVPLPTISGHRELVLSSPEDLTQ---DFEEMKREERALLAEQRDTG-------LG 555
P+ P P++ ++ E+L + D + ERAL RDT L
Sbjct: 4623 PSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERAL----RDTSEVKSLDLLA 4678
Query: 556 DKPFP-----------LDTAEEGPPSTAIQGTPPSV--------PGLGQEEHVMKEKELV 596
P P D + P S +P S+ P LG +++ L
Sbjct: 4679 ALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALS 4738
Query: 597 P--------EVPEEQGSKDRG-LDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPE 647
P +P +K G L + TWE+ K E + + A ++
Sbjct: 4739 PVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNG 4798
Query: 648 VKEDVIEKAELEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFGGRELGLQ 707
V ++ AEL M+ + + ++ G EP K E GG+E GL+
Sbjct: 4799 V---MVAVAELLSMKIPNSYEVLFPESPARAG------TEPKK---GEAEGPGGKEKGLE 4846
Query: 708 GKAPEKETSLFLSSLTTPAGATEHVSYIQDETIPGYSETEQTISDEEIHDEPEERPAPPR 767
GK+P+ T P + D +PGY+ Q + + + P PP
Sbjct: 4847 GKSPD----------TGPDWLKQF-----DAVLPGYTLKSQ-LDILSLLKQESPAPEPPT 4890
Query: 768 FHTSTYDLPGPE----GAGPFEASQPADSAVPATSGKVYGTPETELTYPTNIVAAP 819
H+ TY++ + A P E P S + + P EL PT +A P
Sbjct: 4891 QHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVEL--PTEPLAEP 4944
Score = 39.7 bits (91), Expect = 0.042
Identities = 220/1139 (19%), Positives = 369/1139 (32%), Gaps = 207/1139 (18%)
Query: 1410 QKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDK 1469
Q+ + L+Q+ +Q+ + L+ + + +++ + +Q+ ++ +++ + L+Q+ L+Q+ +
Sbjct: 3901 QQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQ 3960
Query: 1470 ALEPKDKDLEQKDRV--LEQKEKIPEEKDKALDQ-------KVRSVEH-KAPEDTVAEMK 1519
+ + + +Q+ ++ L Q + + + Q + ++H +P +
Sbjct: 3961 QQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLL 4020
Query: 1520 DRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQ 1579
EQ P +A E S + L A+G E++ ++ +
Sbjct: 4021 LTGKEQNTVDPAVSSEATEGP---STHQGGPL-----AIGTTPESMATEPGEVKPSLSGD 4072
Query: 1580 EQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEK 1639
Q LVQ +P L+ + P ++ +++ +LL T G L +
Sbjct: 4073 SQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLH-TAGGGSHGQLGSGSSSEASSVP 4131
Query: 1640 YWRGQDVVQEWQETSPTREEPAGEQKELA--PAWEDTSPEQDN-----RYWRGREDVALE 1692
+ Q V + + G Q+ + P +T P+ + +G V +
Sbjct: 4132 HLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIM 4191
Query: 1693 QDTYWRELSCERKVWFPHELDGQGARPHYTEERESTFLDEGPDDEQEV----PLREHATR 1748
+L + + + P ++ ++ + Q V P +E T+
Sbjct: 4192 PTV--GQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQ 4249
Query: 1749 SPWASDFKDFQES-----SPQKGLEVERWLAESPVGLP--PEEEDKLTRSPF----EIIS 1797
+ Q PQ G E P G P P L+ P
Sbjct: 4250 TSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTP 4309
Query: 1798 PPASPPEMVGQRVPSAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPAPL 1857
PP+SP E +R P S +P +P P TP P P P PP +
Sbjct: 4310 PPSSPQEP--KRPSQLPSPSSQLPTEAQLP--PTHPGTPK------PQGPTLEP-PPGRV 4358
Query: 1858 SPAPG---------------PPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELE---- 1898
SPA PP E+ P S D V V A++L
Sbjct: 4359 SPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQE 4418
Query: 1899 -GGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKV-PEASKSHATTEPEQTEPEQREP 1956
LG K E E G AP S+H P + H + +
Sbjct: 4419 PREEPCALGAQSVKREANGEPIG---APGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLS 4475
Query: 1957 TPYPDERSFQYADIYEQMMLTGLGP---ACPTREPPLGAAGDWPPCLSTKEAAAGRNTSA 2013
T E + + L GL P+ + A P + A+ R S+
Sbjct: 4476 TGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSS 4535
Query: 2014 EKEL-------SSPISPKSLQSD-----------TPTFSYAALAGPTVPPRPEP------ 2049
K+L +S K L+ + T FS A G P +
Sbjct: 4536 RKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAF 4595
Query: 2050 -------GPSM------EPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSPSPKES 2096
GP + +L+ P PP + L P P + +++ +P E
Sbjct: 4596 GSGALPTGPDYYSQLLTKNNLSNPPTPPSS--LPPTPPPSVQQKMVN------GVTPSEE 4647
Query: 2097 GRSHWDDSTSDSELEKGAREQPEKE-----AQSPSPPH----PIPMGS-----------P 2136
H D+ S + E+ R+ E + A P+PPH + M S P
Sbjct: 4648 LGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVP 4707
Query: 2137 TLWPETEAHVSPPLDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAF 2196
PE+ P HLG R + A S + P P+ P P + P G+L
Sbjct: 4708 ASSPESILGEEAPRFPHLGSGRWEQEDRA----LSPVIPLIPRASIPVFPDTKPYGALGL 4763
Query: 2197 S--------------GDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLP---QLPSPSSP 2239
G + ++ + V A L +P ++ P SP
Sbjct: 4764 EVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESP 4823
Query: 2240 GA----PLLSNLPRPASPALSEGSSSEATTPVISSVAERFSPS---------LEAAEQES 2286
P P S T P + P L +QES
Sbjct: 4824 ARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQES 4883
Query: 2287 GELDPGMEPAAHSLW------DLTPLS------PAPPASLDLALAPAPSLPGDMGDGILP 2334
+P P HS D+ LS P+PP S LAP+P+ P LP
Sbjct: 4884 PAPEP---PTQHSYTYNVSNLDVRQLSAPPPEEPSPPPS---PLAPSPASPPTEPLVELP 4937
Query: 2335 CHLECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAACPAWERGAW 2393
+E E P P +P A+ P P P P + E+ W+ W
Sbjct: 4938 -----TEPLAEPPVPSPLP----LASSPESARPKPRARPPEEGEDSRPPRLKKWKGVRW 4987
Score = 39.3 bits (90), Expect = 0.055
Identities = 19/90 (21%), Positives = 48/90 (53%), Gaps = 4/90 (4%)
Query: 1501 QKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQ 1560
Q+++ + + + + + + L+Q + +Q+ Q Q+Q+ ++ +++ Q L+Q+ L Q
Sbjct: 3898 QQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQ 3957
Query: 1561 KDEALEQNIQALEENHQTQEQESLVQEDKT 1590
+ + +Q Q Q Q+Q L+ + +T
Sbjct: 3958 QQQQQQQQFQ----QQQQQQQMGLLNQSRT 3983
Score = 38.5 bits (88), Expect = 0.094
Identities = 102/427 (23%), Positives = 152/427 (35%), Gaps = 72/427 (16%)
Query: 969 ALHPGEPALGEAEERCLSPDDSTVKMASPPPSGPPSATHTPFHQSPVE--EKSEPQDFQE 1026
ALH P EE LSP ++ PP S P +P +SP+ E+S P E
Sbjct: 482 ALHLSRPL----EESPLSPPPEESPLSPPPESSP----FSPLEESPLSPPEESPPSPALE 533
Query: 1027 ADSWGDTKRTPGVGKEDAAEETVKPGPEE----GTLEKEEKVPPPR----SPQAQEAPVN 1078
+ +P E + P PEE E PPP SP +E+P++
Sbjct: 534 TPLSPPPEASP--LSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMS 591
Query: 1079 IDEGLTGCTIQLLPAQDKAIVFEIMEAGEPTGPILGAEALPGGLRTLPQEPGKPQKDEVL 1138
+ +L P +++ + E P P A L P P P++ +
Sbjct: 592 PPPEAS----RLFPPFEESPLSPPPEE-SPLSPPPEASRLSPPPEDSPMSP-PPEESPMS 645
Query: 1139 RYPDRS-LSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRWPEVS-----PE 1192
P+ S LSP +S LS P ++ P +SP PE S PE
Sbjct: 646 PPPEVSRLSP--LPVVSRLSPPPEESPLSPPPEESPTSPP---------PEASRLSPPPE 694
Query: 1193 DTQSLSLSEESPSKETSLD-VSSKQLSPESLGTLQFGELNLGKEEMGHLMQAEDTSH--- 1248
D+ + E+SP+ D + S L L L + E HL + H
Sbjct: 695 DSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSP 754
Query: 1249 -----HTAPMSVPEPHAATASPPTDGTTRYSAQTDITDDSLDRKSPASSFSHSTPSGNGK 1303
H +P + EPH SP + + + SP + H +P
Sbjct: 755 RPEEPHLSPQA-EEPH---LSPQPEEPCLCAVPEE------PHLSPQAEGPHLSPQPEEL 804
Query: 1304 YL------PGAITSPDEHILTPDSSFS----KSPESLPGPALEDIAIKWEDKVPGLKDRT 1353
+L P P+E L+P S +S E P E+ + E + P L R
Sbjct: 805 HLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRP 864
Query: 1354 SEQKKEP 1360
+ +EP
Sbjct: 865 EKPPEEP 871
Score = 36.6 bits (83), Expect = 0.36
Identities = 72/290 (24%), Positives = 111/290 (38%), Gaps = 42/290 (14%)
Query: 530 DLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHV 589
+LT +R+ R L + GL P D T + G G EH+
Sbjct: 1602 NLTMSPLHKRRQRRGRLGLPGEAGLEGSE-PSDALGPDDKKDGDLDTDELLKGEGGVEHM 1660
Query: 590 MKEKELV-PEVPEEQGSKDRGLDSGAETEEEKDTWEEKKQREAER--LPDRTEAREESEP 646
E +L P P+ + K+ ETEE K K++R+ R + + +S
Sbjct: 1661 ECEIKLEGPVSPDVEPGKE-------ETEESK-----KRKRKPYRPGIGGFMVRQRKSHT 1708
Query: 647 EVKEDVIEKAEL----EEMEEVHPSDEEEEDATK---AEGFYQKHMQEPLKVTPRS---- 695
K+ +AE+ + +EV P+D E A + AEG +K Q + +
Sbjct: 1709 RTKKGPAAQAEVLSGDGQPDEVIPADLPAEGAVEQSLAEGDEKKKQQRRGRKKSKLEDMF 1768
Query: 696 ----REAFGGREL-GLQGKAPEKETSLFLSSLTTPAGATEHVSYIQDETIPGYSETEQTI 750
+EAF G+EL L KA LF + P+ D G SE ++
Sbjct: 1769 PAYLQEAFFGKELLDLSRKA------LFAVGVGRPSFGLGTPKAKGD----GGSERKELP 1818
Query: 751 SDEEIHDEPEERPAPPRFHTSTYDLPGPEGAGPFEASQPADSAVPATSGK 800
+ ++ D P+ R D PGPE G + P+D P T G+
Sbjct: 1819 TSQKGDDGPDIADEESRGLEGKADTPGPEDGGVKASPVPSDPEKPGTPGE 1868
Score = 36.6 bits (83), Expect = 0.36
Identities = 71/279 (25%), Positives = 93/279 (33%), Gaps = 35/279 (12%)
Query: 961 PVFSAPGHALHPGEPALGEAEERCLSPDDSTVK-----MASPPPSGPPSATHTPFHQSPV 1015
P AP + L P P SP + + +S P +G P HT +P
Sbjct: 2176 PFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPR 2235
Query: 1016 EEKSEPQDF-----QEADSWGDTKRTPGVGKEDAAEETVKPGP-EEGTLEKEEKVPPPRS 1069
+ S P F D+ +PGVG A+E + P P E E K +
Sbjct: 2236 HQPSTPDPFLKPRCPSLDNLA-VPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGA 2294
Query: 1070 PQAQEAPVN---IDEGLTGCTIQLL----PAQDKAIVFEIMEAGEPTGPILG--AEALPG 1120
P N +D +G + L P KA + EP P LG + P
Sbjct: 2295 SSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPP 2354
Query: 1121 GLRTLPQEPGKPQKDEVLRYPDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQY 1180
P P P Y D P P P Q P P+S C L +
Sbjct: 2355 AQALAPSPPSHPDIFRPGSYTDPYAQPP--------LTPRP----QPPPPESCCALPPRS 2402
Query: 1181 LHKDRWPEVSPEDTQSLSLSEESPSKETSLDVSSKQLSP 1219
L D + V P QS S S +SP L + SP
Sbjct: 2403 LPSDPFSRV-PASPQSQS-SSQSPLTPRPLSAEAFCPSP 2439
Score = 35.0 bits (79), Expect = 1.0
Identities = 41/149 (27%), Positives = 55/149 (36%), Gaps = 35/149 (23%)
Query: 1781 PPEEEDKLTRSPFEIISPPASPPEMVGQRVPSAPGQESPIPDPKLMPHMKNEPTTPSWLA 1840
PP EE SP + PASPP +P+ P E P+P P +P LA
Sbjct: 4909 PPPEEPSPPPSP--LAPSPASPPTEPLVELPTEPLAEPPVPSP--LP-----------LA 4953
Query: 1841 DIPPWVPKDRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTAEYD--SVVAAVQEGAAELE 1898
P RP P A PP +S P W + ++ +Q+G+ E
Sbjct: 4954 SSP---ESARPKPRA------RPPEEGEDSRPPRLKKWKGVRWKRLRLLLTIQKGSGRQE 5004
Query: 1899 GGPYSPLGKDYRKAEGEREEEGRAEAPDK 1927
D R+ E+ G A PDK
Sbjct: 5005 ---------DEREVAEFMEQLGTALRPDK 5024
Score = 34.3 bits (77), Expect = 1.8
Identities = 49/294 (16%), Positives = 123/294 (41%), Gaps = 26/294 (8%)
Query: 1362 PKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTA 1421
P +LQ++ L+ + + Q + L + + +QQ L Q +Q+
Sbjct: 3711 PDSRLLQERQLQLQQQRM---------QLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGP 3761
Query: 1422 LEQKDKALEPKDKDL----EEKDKALEQKDKIPEEKDKAL---EQKDTALEQKDKALEPK 1474
Q ++AL PK + L + ++Q P + + + Q +Q AL P+
Sbjct: 3762 GVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQ 3821
Query: 1475 DKD---LEQKDRVL------EQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQ 1525
L + RVL +Q + + + Q+ + +H+ + ++A +
Sbjct: 3822 GPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQ-QGSMAGLSHLQQSL 3880
Query: 1526 TDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLV 1585
+ + K AQ ++ Q L+Q+ Q+ + L+Q Q ++ Q Q+Q+ +
Sbjct: 3881 MSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQL 3940
Query: 1586 QEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEK 1639
Q+ + ++ + +++ ++ + +++ + ++ + L +S ++Q+++
Sbjct: 3941 QQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQ 3994
Score = 33.9 bits (76), Expect = 2.3
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 10/92 (10%)
Query: 492 IRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLAEQRD 551
++ E+ +S P P G V P+ H L E T D + RA E +
Sbjct: 2287 VKKEELGASSPSYGPPNLGFVDSPSSGTH----LGGLELKTPDVFKAPLTPRASQVEPQS 2342
Query: 552 TGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGL 583
GLG +P +E PP+ A+ +PPS P +
Sbjct: 2343 PGLGLRP------QEPPPAQALAPSPPSHPDI 2368
Score = 33.1 bits (74), Expect = 4.0
Identities = 97/435 (22%), Positives = 132/435 (30%), Gaps = 78/435 (17%)
Query: 956 SQYGTPVFSAPGHALHPGEPALGEAEERCLSPDDSTVKMASPPPSGPPSATHT------- 1008
S G P G L PG P D +++ PPP PS+
Sbjct: 2747 SLVGLPPSKLSGPILGPGS-----------FPSDD--RLSRPPPPATPSSMDVNSRQLVG 2793
Query: 1009 ---PFHQSPVEEKSEPQDFQEADSWGDTKRTPGVGKEDA--AEETVKPGPEEGTLE---- 1059
F+Q S P Q+ W + T A A PGPE G
Sbjct: 2794 GSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSP 2853
Query: 1060 ----------KEEKVPPPRSP-QAQEAPVNIDEGLTGCTIQLLPAQDKAIVFEIMEAGEP 1108
E VP P P Q E N+ +GL G P Q E
Sbjct: 2854 LAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGL-GPGGTPFPGQGPPQRPRFYPVSED 2912
Query: 1109 TGPILGAEALPGGLRTLPQEPGKPQKDEVLRYPDRSLSPEDAESLSVLSVPSPDTANQEP 1168
+ P GLR L PQK P +PE SL P+P T P
Sbjct: 2913 PHRLA-----PEGLRGLAVSGLPPQK------PSAPPAPELNNSLH----PTPHTKG--P 2955
Query: 1169 TPKSPCGLTEQYLHKDRWPEVSPEDTQSLSLSEESPSKETSLDVSSKQLSPESLGTLQFG 1228
T + L + +P ++ L E P + D E L L G
Sbjct: 2956 TLPTGLELVNRPPSSTELGRPNPLALEAGKLPCEDPELDDDFDAHKALEDDEELAHLGLG 3015
Query: 1229 -ELNLGKEEMGHLMQAEDTSHHTAPMSVPEPHAATASPPTDGTTRYSAQTDITDDSLDRK 1287
++ G +E+G L E H + + A TD D+ D+K
Sbjct: 3016 VDVAKGDDELGTLENLETNDPHLDDLLNGDEFDLLA------------YTDPELDTGDKK 3063
Query: 1288 SPASSFSHSTPSGNGKYLPGAITSPDEHILTPDSSFSKSPESLPGPALEDIAIKWEDKVP 1347
+ S N K + E +L PE P PA + + +P
Sbjct: 3064 DIFNEHLRLVESANEK-------AEREALLRGVEPGPLGPEERPPPAADASEPRLASVLP 3116
Query: 1348 GLKDRTSEQKKEPEP 1362
+K + E + P P
Sbjct: 3117 EVKPKVEEGGRHPSP 3131
Score = 32.0 bits (71), Expect = 8.8
Identities = 26/119 (21%), Positives = 55/119 (46%), Gaps = 11/119 (9%)
Query: 1478 LEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQ 1537
L+ + +VLE++ + + KAL K R+ + E + D E+ EQ+ + Q
Sbjct: 3521 LQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAG-----REFPEADAEKLKLVTEQQSKIQ 3575
Query: 1538 EQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKML 1596
+Q D+V + +QK + +Q Q ++ Q Q+ +++ ++ P++L
Sbjct: 3576 KQLDQVRK------QQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLL 3628
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens]
Length = 570
Score = 117 bits (294), Expect = 1e-25
Identities = 74/301 (24%), Positives = 167/301 (55%), Gaps = 21/301 (6%)
Query: 1368 QQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDK 1427
QQ++K +E ++ ++ I +++E + + E +++Q++ + +K + +++ + +K++
Sbjct: 285 QQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 344
Query: 1428 ALEPKDKDLEEKDKALEQKDKIPEEK-----DKALEQKDTALEQKDKALEPKDKDLEQKD 1482
+ ++ + E++K EQ++K EE+ +K EQ+ Q++K E ++K EQ++
Sbjct: 345 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEE 404
Query: 1483 RVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDK 1542
+ EQ+EK+ E+++K +Q E+ + E +++ Q +K EQ+ + +EQ++K
Sbjct: 405 MMQEQEEKMGEQEEKMWEQ----------EEEMQEQEEKMRRQEEKIREQEKKIREQEEK 454
Query: 1543 VSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPE 1602
+ E+++ EQ+ Q+ + EQ + E+ + + QE ++E + +K + EEK E
Sbjct: 455 IREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQE-KKIREQEEKIRE 513
Query: 1603 KVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAG 1662
+ + M+E+ E + E+ E+ QE + +EQEEK R ++ ++E + +EE
Sbjct: 514 QEEMMQEQEEKMWEQE-----EKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQ 568
Query: 1663 E 1663
E
Sbjct: 569 E 569
Score = 110 bits (276), Expect = 1e-23
Identities = 84/304 (27%), Positives = 167/304 (54%), Gaps = 38/304 (12%)
Query: 1343 EDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTL-EHKEVVEPKDTAIYQKDEALHVKNEAV 1401
E+K+ +++ EQ+++ ++E ++++++ + E +E + ++ +++K+E + E +
Sbjct: 294 EEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 353
Query: 1402 KQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKD 1461
+Q+K EQ+ + Q++ + +++K E + K +++K EQ++KI E+++ EQ++
Sbjct: 354 HEQEKIREQEEK--RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEE 411
Query: 1462 TALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQ--KVRSVEH--KAPEDTVAE 1517
EQ++K E +++ EQ++++ Q+EKI E++ K +Q K+R E + E+ + E
Sbjct: 412 KMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGE 471
Query: 1518 MKDRDLEQTDKAPEQ--KHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEEN 1575
+ + EQ K EQ K + QE+K + EKK + E+K I+ EE
Sbjct: 472 QEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEK--------------IREQEEM 517
Query: 1576 HQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRARE 1635
Q QE++ QE+ KM E++ EK++ EEK+ EK + QE R R+
Sbjct: 518 MQEQEEKMWEQEE-----KMCEQE--EKMQEQEEKMRRQEEKMRE--------QEVRLRQ 562
Query: 1636 QEEK 1639
QEEK
Sbjct: 563 QEEK 566
Score = 109 bits (272), Expect = 4e-23
Identities = 86/352 (24%), Positives = 185/352 (52%), Gaps = 30/352 (8%)
Query: 1352 RTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQK 1411
R E+ K P+ ++ + D + + V K A +++E + N+ +Q+
Sbjct: 237 RKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQ---------QQE 287
Query: 1412 GRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKAL 1471
+ Q++ E+++K E ++K E+++K Q++ + E+++K Q++ E+++K
Sbjct: 288 EKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 347
Query: 1472 EPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDT-VAEMKDRDLEQTDKAP 1530
E ++K + +++++ EQ+EK EE +K+R E + ++ + +++ EQ +K
Sbjct: 348 ELEEK-MHEQEKIREQEEKRQEE------EKIREQEKRQEQEAKMWRQEEKIREQEEKIR 400
Query: 1531 EQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKT 1590
EQ+ QEQ++K+ E+ E+K W ++ + E+ ++ EE + QE++ QE+K
Sbjct: 401 EQEEMMQEQEEKMGEQ-----EEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKI 455
Query: 1591 RKPKMLEEKSPEKVKAMEEKL---EALLEKTKALGLEESLVQEGRAREQEEKYWRGQDVV 1647
R+ + + ++ EK+ E K+ EA +++ + E+ QE + REQE+K ++ +
Sbjct: 456 REQEEMMQEQEEKMGEQEGKMCEQEAKMQEQE----EKMRRQEEKIREQEKKIREQEEKI 511
Query: 1648 QEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQDTYWRE 1699
+E +E +EE EQ+E E+ EQ+ + R +E+ EQ+ R+
Sbjct: 512 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK-MRRQEEKMREQEVRLRQ 562
Score = 104 bits (260), Expect = 1e-21
Identities = 66/271 (24%), Positives = 157/271 (57%), Gaps = 11/271 (4%)
Query: 1343 EDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKE-VVEPKDTAIYQKDEALHVKN--- 1398
E+K+ +++ EQ+++ ++E++ +K++ + +E ++ K+ I + +E +H +
Sbjct: 301 EEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 360
Query: 1399 --EAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKA 1456
E +Q+++ + ++ + EQ+ Q++K E ++K E+++ EQ++K+ E+++K
Sbjct: 361 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM 420
Query: 1457 LEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVA 1516
EQ++ EQ++K ++K EQ+ ++ EQ+EKI E+++ +Q+ + E + +
Sbjct: 421 WEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEG-KMCEQ 479
Query: 1517 EMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENH 1576
E K ++ E+ + E+K + EQ+ K+ E++++ EQ+ Q+++ EQ + E+
Sbjct: 480 EAKMQEQEEKMRRQEEKIR--EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 537
Query: 1577 QTQEQESLV--QEDKTRKPKMLEEKSPEKVK 1605
+ QEQE + QE+K R+ ++ + EK++
Sbjct: 538 KMQEQEEKMRRQEEKMREQEVRLRQQEEKMQ 568
Score = 103 bits (258), Expect = 2e-21
Identities = 63/239 (26%), Positives = 145/239 (60%), Gaps = 10/239 (4%)
Query: 1336 EDIAIKWEDKVPGLKDRTSEQKK-----EPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQK 1390
E++ + E+K+ L+++ EQ+K E ++E +++++K E + + ++ I ++
Sbjct: 336 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 395
Query: 1391 DEALHVKNEAVKQQDKAL-EQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKI 1449
+E + + E +++Q++ + EQ+ + EQ++ EQ++K ++K E++ K EQ++KI
Sbjct: 396 EEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKI 455
Query: 1450 PEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHK 1509
E+++ EQ++ EQ+ K E + K EQ++++ Q+EKI E++ K +Q+ + E
Sbjct: 456 REQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ- 514
Query: 1510 APEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQN 1568
E+ + E +++ EQ +K EQ+ + QEQ++K+ ++++ EQ+ L Q++E ++++
Sbjct: 515 --EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEV-RLRQQEEKMQEH 570
Score = 100 bits (250), Expect = 2e-20
Identities = 90/361 (24%), Positives = 183/361 (50%), Gaps = 40/361 (11%)
Query: 1364 DEVLQQKDKTLEHK-EVVEPKDTAIYQKDEALHVKNEAVK------QQDKALEQKGRDLE 1416
DE L++K+ L+ K ++VE + + I + L K E K Q + G++L+
Sbjct: 204 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 263
Query: 1417 QKDTALEQKDKALEPKDK-DLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKD 1475
L+ + + E ++ + ++++K Q++KI E ++K EQ E K
Sbjct: 264 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQ------------EEKI 311
Query: 1476 KDLEQKDR-----VLEQKEKI--PEEKDKALDQKVRSVEHKAPE-DTVAEMKDRDLEQTD 1527
++ E+K R + E++EK+ EE ++K+R +E K E + + E +++ E+
Sbjct: 312 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 371
Query: 1528 KAPEQKHQAQE-----QKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQE 1582
++K Q QE Q++K+ E++++ EQ+ Q+++ EQ + E+ + QEQE
Sbjct: 372 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQE 431
Query: 1583 SLV--QEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLV--QEGRAREQEE 1638
+ QE+K R+ + + EK++ EE ++ E+ + +G +E + QE + +EQEE
Sbjct: 432 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQ---EQEEKMGEQEGKMCEQEAKMQEQEE 488
Query: 1639 KYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQDTYWR 1698
K R ++ ++E ++ +EE EQ+E+ E+ EQ+ + E + +++ R
Sbjct: 489 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 548
Query: 1699 E 1699
+
Sbjct: 549 Q 549
Score = 66.2 bits (160), Expect = 4e-10
Identities = 64/340 (18%), Positives = 155/340 (45%), Gaps = 37/340 (10%)
Query: 311 SKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKP 370
+K++ + + E + K+ ++EE ++E +E E +++ + E+K + E
Sbjct: 267 AKLQAQVEENELWNRLNQQQEEKMWRQEEKIQE-REEKIQEQEEKIREQEEKMRRQEEMM 325
Query: 371 PEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKEL 430
EK K R E + EK + I++ K H +EKI + EEK+ +E+K ++E+++
Sbjct: 326 WEKEEKMRR-----QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 380
Query: 431 KKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVKIDRSR 490
++ + ++E+K ++EEK ++ + +++ + ++ +
Sbjct: 381 QEAKMWRQEEKIREQEEKIREQEEMMQEQEE---------------------KMGEQEEK 419
Query: 491 AIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLAEQR 550
E+E+ + + Q+ + +E + E+ ++ EEM +E+ + EQ
Sbjct: 420 MWEQEEEMQEQEEKMRRQEEKI------REQEKKIREQEEKIREQEEMMQEQEEKMGEQ- 472
Query: 551 DTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKDRGL 610
+ + ++ + EE + QEE + +++E++ E E+ ++ +
Sbjct: 473 EGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKM 532
Query: 611 DSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVKE 650
E EE+ EEK +R+ E++ ++ + E +++E
Sbjct: 533 ---CEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 65.1 bits (157), Expect = 9e-10
Identities = 83/384 (21%), Positives = 172/384 (44%), Gaps = 28/384 (7%)
Query: 314 KQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEK 373
K++AD + A+S R + +E KE ++L ++L E + E E
Sbjct: 176 KKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKEL 235
Query: 374 PAKPERVKTE-SSEALKAEKRKLIKD----------KVGKKHLKEKISKLEEKK--DKEK 420
K ER K + L+AE L K+ +V + L ++++ +E+K +E+
Sbjct: 236 KRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEE 295
Query: 421 KEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKV 480
K ++E K +++E +E+++ +++E+ K E K+ + + + E + + K+
Sbjct: 296 KIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEE--KMRRQEEMMWEKEEKIRELEEKM 353
Query: 481 PGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKR 540
+ KI R E+E E + Q+ + +E + E+ ++ EEM +
Sbjct: 354 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKM------WRQEEKIREQEEKIREQEEMMQ 407
Query: 541 EERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVP 600
E+ + EQ + + ++ + EE + QEE + +++E++ E
Sbjct: 408 EQEEKMGEQEEK-MWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQE 466
Query: 601 EEQGSKDRGL---DSGAETEEEKDTWEEKKQREAE-RLPDRTEAREESEPEVKEDVIEKA 656
E+ G ++ + ++ + +EEK +E+K RE E ++ ++ E E E ++E +
Sbjct: 467 EKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 526
Query: 657 ELEE--MEEVHPSDEEEEDATKAE 678
E EE E+ E+EE + E
Sbjct: 527 EQEEKMCEQEEKMQEQEEKMRRQE 550
Score = 56.6 bits (135), Expect = 3e-07
Identities = 68/385 (17%), Positives = 166/385 (43%), Gaps = 66/385 (17%)
Query: 309 KPSKIKQRADSKESLKATTKTAVSKLAKREE-----VVEEGAKEARSELAKELAKTEKKA 363
K +K++++ ES K+ + V +L ++ E + ++ + L KEL K
Sbjct: 210 KNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL 269
Query: 364 KESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKK------- 416
+ E+ R+ + E + ++ K+ + + + +EKI + EEK
Sbjct: 270 QAQVEENELW----NRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMM 325
Query: 417 -DKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTL 475
+KE+K ++E +K+E +E ++ ++EK ++ + + ++ K + E +
Sbjct: 326 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 385
Query: 476 YKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDF 535
++ + R ++ IR ++E+ E + ++ E + E++ +
Sbjct: 386 WRQEEKIR---EQEEKIREQEEMMQEQEEKMGEQ-----------EEKMWEQEEEMQEQE 431
Query: 536 EEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKEL 595
E+M+R+E + +++ QEE + +++E+
Sbjct: 432 EKMRRQEEKIREQEKKI------------------------------REQEEKIREQEEM 461
Query: 596 VPEVPEEQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVK--EDVI 653
+ E E+ G ++ + E E + EEK +R+ E++ ++ + E E +++ E+++
Sbjct: 462 MQEQEEKMGEQEGKM---CEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 518
Query: 654 EKAELEEMEEVHPSDEEEEDATKAE 678
++ E + E+ E+EE + E
Sbjct: 519 QEQEEKMWEQEEKMCEQEEKMQEQE 543
Score = 56.2 bits (134), Expect = 4e-07
Identities = 93/452 (20%), Positives = 186/452 (41%), Gaps = 83/452 (18%)
Query: 323 LKATTKTAVSKLAKREEVVEEGAKEARSELAKELAK---TEKKAKESSEKPPEKPAKPER 379
L+ ++ K + +EE KE R L+ EL + T+++ KE + K EK E
Sbjct: 165 LEQALSAVATQKKKADRYIEELTKE-RDALSLELYRNTITDEELKEKNAKLQEKLQLVES 223
Query: 380 VKTESSEALKAEKRKLIKDKV--GKKHLKEKISKL--EEKKDKEKKEIKKERKELKKDEG 435
K+E +K KRKL + K+ ++ L+ + L E + K + + E EL
Sbjct: 224 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 283
Query: 436 RKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVKIDRSRAIRGE 495
+++E+K ++EEK ++ + ++++ + ++R+ K + + ++ +R +
Sbjct: 284 QQQEEKMWRQEEKIQEREEKIQEQEE--------KIREQEEKMRRQEEMMWEKEEKMRRQ 335
Query: 496 KELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLG 555
+E+ E + + H + + E+ Q+ E+++ +E+ E +
Sbjct: 336 EEMMWEKEEKIRELEE------KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 389
Query: 556 DKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAE 615
+K QEE + +++E++ E E+ G
Sbjct: 390 EKIRE------------------------QEEKIREQEEMMQEQEEKMG----------- 414
Query: 616 TEEEKDTWE--EKKQREAERLPDRTEAREESEPEVKEDVIEKAELEEMEEVHPSDEEEED 673
E+E+ WE E+ Q + E++ + E E E +++E + E EEM + E+EE
Sbjct: 415 -EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ-----EQEEK 468
Query: 674 ATKAEG---FYQKHMQEPLKVTPRSREAFGGRELGLQGKAPEKETSLFLSSLTTPAGATE 730
+ EG + MQE + R E +E K E+E + E
Sbjct: 469 MGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQE----KKIREQEEKI-----------RE 513
Query: 731 HVSYIQDETIPGYSETEQTISDEEIHDEPEER 762
+Q++ + + E+ EE E EE+
Sbjct: 514 QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 545
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 108 bits (270), Expect = 7e-23
Identities = 224/967 (23%), Positives = 332/967 (34%), Gaps = 213/967 (22%)
Query: 1800 ASPPEMVGQRVPSAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSP 1859
A PP V Q VP A P + L P K S +PP +P P P P P
Sbjct: 201 AEPP--VVQPVPPA-ALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPP 257
Query: 1860 APGPPTPAPESHTPAPFS------WGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAE 1913
P PP P P T PF W T L G + P K A
Sbjct: 258 PPPPPPPLPGLATSPPFQLTKPGLWST----------------LHGDAWGPERKG--SAP 299
Query: 1914 GEREEEGRA-------EAPDKSSH--SSKVPEASKSHATTEPEQTEPEQREPTPYPDERS 1964
ER+E+ + AP ++H ++ A+ P E P P
Sbjct: 300 PERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSD 359
Query: 1965 FQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCL----STKEAAAGRNTSAEKELSSP 2020
+ + + M + + PA T P A PP L ++ +++ NT +P
Sbjct: 360 LRESRVQRSRMDSSVSPAATTACVPY--APSRPPGLPGTTTSSSSSSSSNTGLRGVEPNP 417
Query: 2021 ISPKSLQSDTPTF--SYAALAGPTVPPRPEP---GPSMEPSLTPPA-----VPPRAPILS 2070
P + TP S+ GP+ +P P+ P L+ P PP P L
Sbjct: 418 GIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLL 477
Query: 2071 KGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPHP 2130
+ P PP +C R +D EL G P P+PP P
Sbjct: 478 RPPPPPAWLKGPACRAAR-------------EDGEILEELFFGTEGPPR-----PAPP-P 518
Query: 2131 IPMGSPTLWPETEAHVSPPLDSHLGPARPS--------------------LDFPASAFGF 2170
+P L P DSH P P+ + FP +
Sbjct: 519 LPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLA 578
Query: 2171 SSLQPAPPQLPSPAE-PRSAPCGSLAFSGDRALALAPGPPTRTRHDEY--LEVTKAPSLD 2227
S+ P P + PSPA+ P+ P L LAL P PP+ + ++P
Sbjct: 579 RSIDPLP-RPPSPAQNPQDPPLVPLT------LALPPAPPSSCHQNTSGSFRRPESPRPR 631
Query: 2228 SSLPQLPS--PSSPGAPLLSNLPRPASPALSEGSSSEAT------TPV------------ 2267
S P+ P P P PL S P+P P + E + TP+
Sbjct: 632 VSFPKTPEVGPGPPPGPL-SKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKI 690
Query: 2268 ----ISSVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPL-SPAPPASLDLALAPAP 2322
++++ + S+ E+E + + G+ P L SP P + APA
Sbjct: 691 LPDGLANIMKMLDESIRK-EEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAV 749
Query: 2323 SLPGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANGPTETS--PNPPGPAPAKAENE 2380
++ ++ +KP P P A P P PP P+PA
Sbjct: 750 AVTTTT---TTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKS 806
Query: 2381 EAAACPAWERGAWPEGAERSSRPDTLLSPE-QPVCPAGGSGGPPSSASPEVEAGPQGCAT 2439
A+ + GA S+RP L + + P P+G + PP+SA+P + PQ
Sbjct: 807 LASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQ---- 862
Query: 2440 EPRPHRGELSPSFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETP 2499
P + ST G R R G GP T P
Sbjct: 863 ------------------PSASSSSQFSTSG----GPWARERRAGEEPVPGPMTPTQPPP 900
Query: 2500 PTSASDSGSSQSDSDVPPE-TEECPSITAEAALDSDEDGDFLPVDKAGGV-SGTHHPRPG 2557
P S ++S+S+V E + C ++ + + D PVD A SGT P
Sbjct: 901 PLSLP---PARSESEVLEEISRACETLVERVGRSATDPAD--PVDTAEPADSGTERLLP- 954
Query: 2558 HDPPPLPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGR---------VGR- 2607
P + G+++ SG +R +++ + + R VGR
Sbjct: 955 -----------------PAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRR 997
Query: 2608 ----RAPGKAK-PASPARRL---------DLRGKRSPTPGKGPADRA----SRAPPRPRS 2649
RA KAK P +RR+ +++G+ P G A +A + APP +
Sbjct: 998 PREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPA 1057
Query: 2650 TTSQVTP 2656
++Q TP
Sbjct: 1058 PSAQPTP 1064
Score = 65.5 bits (158), Expect = 7e-10
Identities = 148/655 (22%), Positives = 210/655 (32%), Gaps = 116/655 (17%)
Query: 2050 GPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSE 2109
GP ++ + PP V P P GPS + SP K + + +
Sbjct: 194 GPPVKRAAEPPVVQPVPPAALSGPS----------GEEGLSPGGKRRRGCNSEQTGLPPG 243
Query: 2110 LEKGAREQPEKEAQSPSPPHPIP---------MGSPTLW---------PETEAHVSPPLD 2151
L P P PP P+P + P LW PE + P
Sbjct: 244 LPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQ 303
Query: 2152 SHLGPARPSLDFPASAFGF----SSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPG 2207
+PA A+ L PA P P P P + G L + L
Sbjct: 304 EQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRES 363
Query: 2208 PPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPV 2267
R+R D + + P P P PG S+ +S + + G P
Sbjct: 364 RVQRSRMDSSVSPAATTACVPYAPSRP-PGLPGTTTSSS----SSSSSNTGLRGVEPNPG 418
Query: 2268 ISSVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAPAPSLPGD 2327
I +P+LE + G L P+AHS P AP A+ L+L P PS P
Sbjct: 419 IPGADHYQTPALEVSHH--GRLG----PSAHS--SRKPFLGAPAATPHLSLPPGPSSPPP 470
Query: 2328 MGDGILPCHLECSEAATEKPSPFQVPSEDC-AANGPTET-------SPNPPGPAPAKAEN 2379
C P P + C AA E + PP PAP +
Sbjct: 471 P---------PCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPH 521
Query: 2380 EEAAACPAWERGAWPEGAERSSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCAT 2439
E P R + G + S P T P P + S S+SP AGP +
Sbjct: 522 REGFLGPPASR--FSVGTQDSHTPPT---PPTPTTSSSNSNSGSHSSSP---AGP--VSF 571
Query: 2440 EPRPHRGELSPSFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETP 2499
P P+ PP P + ++ LV P+T P
Sbjct: 572 PPPPYLARSIDPLPRPPSPAQ------NPQDPPLV------------------PLTLALP 607
Query: 2500 PTSASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAG-------GVSGTH 2552
P S + S S PE+ P ++ + P+ KA G
Sbjct: 608 PAPPSSCHQNTSGSFRRPESPR-PRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPAR 666
Query: 2553 HPRPGHDPPPLPQPDPRPSPPRPDVCMADPEGLSSESGRV-ERLREKEKVQGRVGRRAPG 2611
PR D PP P D P + P+GL++ + E +R++E+ Q AP
Sbjct: 667 GPRL-FDFPPTPLEDQFEEPAEFKIL---PDGLANIMKMLDESIRKEEEQQQHEAGVAP- 721
Query: 2612 KAKPASPARRLDLRGKRSPTP-GKGPADRASRAPPRPRSTTSQVTPAEEKDGHSP 2665
P + +SP P P A +TT+ T A +++ P
Sbjct: 722 -----QPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKP 771
Score = 40.4 bits (93), Expect = 0.025
Identities = 134/577 (23%), Positives = 178/577 (30%), Gaps = 102/577 (17%)
Query: 2167 AFGFSSLQPAPPQLPSPAEPRSA--PCGSLAFSGDRALALAPGPPTRTRHDEYLEVTKAP 2224
A +SS P PP PRSA P G + S + AP PP+ + P
Sbjct: 25 AGAWSSCPPHPP-------PRSAWLPGGRCSASIGQPPLPAPLPPSHGSSSGH------P 71
Query: 2225 SLDSSLPQLPSPSSPGAPLLSN-------LPRPASPAL---------SEGSSSEATTPVI 2268
S P P+P L S L PA P L SE S EAT
Sbjct: 72 SKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESEHDSEEATRCYH 131
Query: 2269 SSVAERFSPSLEAAEQESGELDPG---------------MEPAAHSLWDLTPLS------ 2307
S++ R+ S G L + P +W+L L
Sbjct: 132 SAL--RYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLLHLEHKRNYG 189
Query: 2308 ------PAPPASLDLALAPAP--SLPGDMGD-GILPCHLE---CSEAATEKPSPFQVPSE 2355
P A+ + P P +L G G+ G+ P C+ T P +P
Sbjct: 190 AKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPP 249
Query: 2356 DCAANGPTETSPNPPGPAPAKAENEEAAACPAWER---GAW-PEGA-----ERSSRPDTL 2406
P P PP P A + + W AW PE ER + +L
Sbjct: 250 PLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSL 309
Query: 2407 LSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPPLPPSIDDRDL 2466
P PA + P P GP PRP E S L PP D R+
Sbjct: 310 PHPYPYPAPAYTAHPPGHRLVPAAPPGPG-----PRPPGAE-SHGCLPATRPPGSDLRES 363
Query: 2467 STEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPP----TSASDSGSSQSDSDVPPETEEC 2522
+ R+ P T P PP T+ S S SS S++ + E
Sbjct: 364 RVQRSRMDSSVS------PAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRG-VEPN 416
Query: 2523 PSITAE-----AALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRPDV 2577
P I AL+ G P + P P P P PP P +
Sbjct: 417 PGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRL 476
Query: 2578 CMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASP--ARRLDLRGKRSPTPGKG 2635
P + RE ++ + G +PA P R G + G
Sbjct: 477 LRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVG 536
Query: 2636 PADRASRAPPRPRSTTSQVTPAEEKDGHSPMSKGLVN 2672
D S PP P + T+ + HS G V+
Sbjct: 537 TQD--SHTPPTPPTPTTS-SSNSNSGSHSSSPAGPVS 570
Score = 40.4 bits (93), Expect = 0.025
Identities = 104/449 (23%), Positives = 146/449 (32%), Gaps = 98/449 (21%)
Query: 1781 PPEEEDKLTRSPFEIISPPASPPEMVG-------QRVPSAPGQESPIPDPKLMPHMKNEP 1833
P +E +SPF + P + V +A +E P P L P
Sbjct: 724 PLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPP------ 777
Query: 1834 TTPSWLADIPPWVPKDRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTAE-YDSVVAAVQE 1892
P LA PP P P P P PP+PA + A G Y AAV
Sbjct: 778 --PPPLAKFPP--------PSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVST 827
Query: 1893 GAAELEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHA-TTEPEQTEP 1951
L YSP G + AP S+ S P AS S +T
Sbjct: 828 RPGPLPTTQYSP-----GPPSGATALPPTSAAP--SAQGSPQPSASSSSQFSTSGGPWAR 880
Query: 1952 EQR---EPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAG 2008
E+R EP P GP PT+ PP + PP S E
Sbjct: 881 ERRAGEEPVP---------------------GPMTPTQPPPPLSL---PPARSESEVLEE 916
Query: 2009 RNTSAEKELSSPISPKSLQSDTPTFSYAALAGPTVPPRPEPGPSMEP--SLTPPAVPPRA 2066
+ + E + G + +P + EP S T +PP
Sbjct: 917 ISRACE-------------------TLVERVGRSATDPADPVDTAEPADSGTERLLPPAQ 957
Query: 2067 PILSKGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPS 2126
G ++G SC RR ++ R H + DS + + + +A+ P
Sbjct: 958 AKEEAGGVAAVSG---SCK--RRQKEHQKEHRRH-RRACKDSVGRRPREGRAKAKAKVPK 1011
Query: 2127 PPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEP 2186
+G+ L E G + D ++ PAPP P+P+
Sbjct: 1012 EKSRRVLGNLDLQSEEIQ----------GREKSRPDLGGASKAKPPTAPAPPSAPAPSAQ 1061
Query: 2187 RSAPCGSLAFSGDRALALAPGPPTRTRHD 2215
+ P S+ G +A APGPP +R D
Sbjct: 1062 PTPPSASVP--GKKAREEAPGPPGVSRAD 1088
Score = 34.7 bits (78), Expect = 1.4
Identities = 95/420 (22%), Positives = 139/420 (33%), Gaps = 72/420 (17%)
Query: 2339 CSEAATEKPSPFQVPSEDCAANG-PTET--SPNPPGPAPAKAENEEAAAC-------PAW 2388
CS + + P P +P +++G P++ +P P P P + E C PA
Sbjct: 47 CSASIGQPPLPAPLPPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPA- 105
Query: 2389 ERGAWPE-GAERSSRPDTLLSPEQPVC--PAGGSGGPPSSASPEV----EAGPQGCATEP 2441
+ G W + G S D S E C A GG + P + +A T
Sbjct: 106 QPGLWEQLGQLYESEHD---SEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGS 162
Query: 2442 RPHRGELSPSFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPPT 2501
HR ++ LPP +L E + G +R G P PV PP
Sbjct: 163 CQHRAKV--------LPPLEQVWNLLHLEHKR--NYGAKRGGPPVKRAAEPPVVQPVPPA 212
Query: 2502 SASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPP 2561
+ S + S C S ++ G G P PP
Sbjct: 213 ALSGPSGEEGLSPGGKRRRGCNS------------------EQTGLPPGLPLP-----PP 249
Query: 2562 PLPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGRV-GRRAPGKAKPASPAR 2620
PLP P P P PP P + P +S ++ + + G G G A P +
Sbjct: 250 PLPPPPPPPPPPPPPL----PGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQ 305
Query: 2621 RLDLRGKRSPTPGKGPADRASRAPPRPRSTTSQV------TPAEEKDGHSPMSKGLVNGL 2674
R L P P PA + PP R + P E G P ++ + L
Sbjct: 306 RHSL-----PHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL 360
Query: 2675 KAGPMALSSKGSSGAPVYVD--LAYIPNHCSGKTADLDFFRRVRASYYVVSGNDPANGEP 2732
+ + S SS +P + Y P+ G +S + G +P G P
Sbjct: 361 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP 420
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 105 bits (262), Expect = 6e-22
Identities = 154/630 (24%), Positives = 246/630 (39%), Gaps = 70/630 (11%)
Query: 999 PSGPPSATHTPFHQSP---VEEKSEPQDFQEADSWGDTKRTPGVGKEDAAEETVKPGPEE 1055
P P +TH V EKSE + + +T+ T V +E+ E + G EE
Sbjct: 427 PKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEE 486
Query: 1056 GTLEKEEKV---PPPRSPQAQEAPVNIDEGLTGCTIQLLPAQDKAIVFEIMEAGEPTGPI 1112
E+EE +SP A+EA E + P +++A E P
Sbjct: 487 EGGEEEEAEGGEEETKSPPAEEAASPEKEAKS-------PVKEEA-----KSPAEAKSPE 534
Query: 1113 LGAEALPGGLRTLPQEPGKPQKDEVLRYPDRSLSPEDAESLSVLSVPSPDTANQ--EPTP 1170
P +++ P++ P K+E + P + SPE E+ S V SP+ A +
Sbjct: 535 KEEAKSPAEVKS-PEKAKSPAKEEA-KSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEA 592
Query: 1171 KSPCGLTEQYLHKDRWPEVSPEDTQSLSLSEESPSKETSLDVSSKQLSPESLGTLQFGEL 1230
KSP SPE +S E E V + SP + + + +
Sbjct: 593 KSPAEAK------------SPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAK- 639
Query: 1231 NLGKEEMGHLMQAEDTSHHTA--PMSVPEPHAATASPPTDGTTRYSAQTDITDDSLDRKS 1288
+ KEE +A+ A P P A A P + A+ + + KS
Sbjct: 640 SPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA---KS 696
Query: 1289 PASSFSHS-----TPSGNGKYLPGAITSP-DEHILTPDSSFS------KSPESLPGPALE 1336
P + S +P P SP E TP+ + S KSPE P
Sbjct: 697 PVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSP--- 753
Query: 1337 DIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHV 1396
+ A + K P K E+ + P K +K K+ +EV P+ K++A
Sbjct: 754 EKAKTLDVKSPEAKTPAKEEARSPADK---FPEKAKSPVKEEVKSPEKAKSPLKEDAKAP 810
Query: 1397 KNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPK----DKDLEEKDKALEQKDKIPEE 1452
+ E K+++ K + Q+ E KA E K K E+KD E+ K
Sbjct: 811 EKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAP 870
Query: 1453 KDKALEQKDTALEQ-KDKALEPKDKDLEQKDRVLEQKEKIP---EEKDKALDQKVRSVEH 1508
K K E+K+ A+E+ K+ +E K ++ E K +V +++ P E K+ A ++ V
Sbjct: 871 KPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAK 930
Query: 1509 KAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQN 1568
K P+D A+ + E+ + APE+K +E+ K EK + K E +
Sbjct: 931 KEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPK 990
Query: 1569 IQALEENHQTQEQES----LVQEDKTRKPK 1594
+ E++ T +++S EDK K K
Sbjct: 991 AEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
Score = 96.3 bits (238), Expect = 4e-19
Identities = 123/539 (22%), Positives = 232/539 (43%), Gaps = 49/539 (9%)
Query: 1157 SVPSPDTANQEPTPKSPCGLTEQYLHKDRWPEVSPEDTQSLSLSE-ESPSKETSLDVSSK 1215
S P+ + A+ E KSP + E+ K SPE ++ S +E +SP K S
Sbjct: 503 SPPAEEAASPEKEAKSP--VKEEA--KSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEA 558
Query: 1216 QLSPESLGTLQFGELNLGKEEMGHLMQAEDTSHHTAPMSVPEPHAATASPPTDGTTRYSA 1275
+ PE+ KEE A+ + +P P A P + + A
Sbjct: 559 KSPPEAKSP--------EKEE------AKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKA 604
Query: 1276 QTDITDDSLDRKSPASSFSHSTPSGNGKYLPGAITSPDEHILTPDSSFSKSPESLPGPAL 1335
++ + +++ KSPA + S P P + SP E +P +KSPE P
Sbjct: 605 KSPVKEEA---KSPAEAKS---PVKEEAKSPAEVKSP-EKAKSPTKEEAKSPEKAKSPEK 657
Query: 1336 EDIAIKWEDKVPGLKDRTSEQK-KEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEAL 1394
E+ + K P + S +K K P + +K K+ +E P+ K+EA
Sbjct: 658 EEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAK 717
Query: 1395 HVKN--EAVKQQDKALEQKGRDLEQKDTALE-----QKDKALEPKDKDLEE--KDKALEQ 1445
+ VK++ K E+ ++++ + E +K K L+ K + + K++A
Sbjct: 718 SPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSP 777
Query: 1446 KDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIP---EEKDKALDQK 1502
DK PE+ ++++ ++ +KA P +D + ++ + +KE++ +E++K + K
Sbjct: 778 ADKFPEKAKSPVKEE---VKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVK 834
Query: 1503 VRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQ-KYWALGQK 1561
V+ KA E+ A + E+ D E+ + + K KV EKK+ A+E+ K + K
Sbjct: 835 VKEPPKKAEEEK-APATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAK 893
Query: 1562 DEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKAL 1621
E E + + + + ++ K ++ + +K P+ KA E A + K
Sbjct: 894 KEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPA---EKKEA 950
Query: 1622 GLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWE--DTSPEQ 1678
E+ +E +A++ EEK ++ + S +P E+ E + + + D+ P +
Sbjct: 951 APEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPE 1009
Score = 88.2 bits (217), Expect = 1e-16
Identities = 110/427 (25%), Positives = 183/427 (42%), Gaps = 28/427 (6%)
Query: 311 SKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAK---EARS-ELAKELAKTEKKAKES 366
+K A S E K+ K A+ + V+E AK E +S E AK K E K+ E
Sbjct: 592 AKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEK 651
Query: 367 SEKPPEKPAK-PERVKTE-SSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIK 424
++ P ++ AK PE+ K+ +EA EK K K K K EE K EK +
Sbjct: 652 AKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSP 711
Query: 425 KERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLY----KAKV 480
+ + ++ + K++AK EK K +K+ +K K +PE KTL +AK
Sbjct: 712 VKEEAKSPEKAKSPVKEEAKTPEKAKSP---VKEEAKSPEKAKSPEKAKTLDVKSPEAKT 768
Query: 481 PGRVKIDRSRAIRGEKELSS--EPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEM 538
P + + RS A + ++ S + + +K PL + E + E++ +E
Sbjct: 769 PAKEEA-RSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEE 827
Query: 539 KREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEH----VMKEKE 594
++ + + E +K EE S + P EE V K KE
Sbjct: 828 EKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKE 887
Query: 595 LVPEVPEEQGSKDRGL-----DSGAETEEEKDTWEEKKQREAERLPDRTEAREESEP-EV 648
E +E+ + + ++ A+ E ++D ++K A++ PD +A+E S+P E
Sbjct: 888 SKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEK 947
Query: 649 KEDVIEKAELEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFGGRELGLQG 708
KE EK + +E + P ++ + +A KA+ + +EP K E +
Sbjct: 948 KEAAPEKKDTKEEKAKKPEEKPKTEA-KAKEDDKTLSKEPSKPKAEKAEKSSSTD-QKDS 1005
Query: 709 KAPEKET 715
K PEK T
Sbjct: 1006 KPPEKAT 1012
Score = 87.0 bits (214), Expect = 2e-16
Identities = 98/376 (26%), Positives = 165/376 (43%), Gaps = 42/376 (11%)
Query: 311 SKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAK--EARSELAKELAKTEKKAK---E 365
S +K A S E K+ K K + V+E AK E KE AK+ +KAK +
Sbjct: 668 SPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVK 727
Query: 366 SSEKPPEKPAKPERVKTESSEALKA-EKRKL--IKDKVGKKHLKEKISKLEEK-KDKEKK 421
K PEK P + + +S E K+ EK K +K K KE+ +K +K K
Sbjct: 728 EEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKS 787
Query: 422 EIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKA--- 478
+K+E K +K + K+DAK EK K E+K K + KP +V++ KA
Sbjct: 788 PVKEEVKSPEK--AKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEE 845
Query: 479 KVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEM 538
K P K + EK+ S + + P K P P + +E + P++ + ++
Sbjct: 846 KAPATPKTE-------EKKDSKKEEAP---KKEAPKPKVEEKKEPAVEKPKESKVEAKKE 895
Query: 539 KREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPE 598
+ E++ ++ T + P ++ E+ P + P + + K E
Sbjct: 896 EAEDK----KKVPTPEKEAPAKVEVKEDAKPKEKTE-VAKKEPDDAKAKEPSKPAEKKEA 950
Query: 599 VPEEQGSKDRGLDSGAETEEEKDTWEEKKQREAE-RLPDRTEAREESEPEVKEDVIEKAE 657
PE++ +K EE+ EEK + EA+ + D+T ++E S+P K + EK+
Sbjct: 951 APEKKDTK----------EEKAKKPEEKPKTEAKAKEDDKTLSKEPSKP--KAEKAEKSS 998
Query: 658 LEEMEEVHPSDEEEED 673
+ ++ P ++ ED
Sbjct: 999 STDQKDSKPPEKATED 1014
Score = 81.3 bits (199), Expect = 1e-14
Identities = 72/251 (28%), Positives = 110/251 (43%), Gaps = 33/251 (13%)
Query: 281 EKLRHLDFLRYPVATQKDLASGAVPTNLKPSK--------IKQRADSKESLKATTKTAVS 332
EK + LD ++ P A P + P K +K +K LK K
Sbjct: 754 EKAKTLD-VKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEK 812
Query: 333 KLAKREEV--------------VEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPE 378
++ K+EEV V+E K+A E A KTE+K E+ P+K A
Sbjct: 813 EIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKP 872
Query: 379 RVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKE 438
+V+ + A++ K ++ K + K+K+ EK+ K E+K++ K +K E K+
Sbjct: 873 KVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPT-PEKEAPAKVEVKEDAKPKEKTEVAKK 931
Query: 439 EKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKEL 498
E DAK +E +KP KK + P+ K E KAK P ++A +K L
Sbjct: 932 EPDDAKAKEP---SKPAEKKEAAPEKKDTKEE------KAKKPEEKPKTEAKAKEDDKTL 982
Query: 499 SSEPQTPPAQK 509
S EP P A+K
Sbjct: 983 SKEPSKPKAEK 993
Score = 75.9 bits (185), Expect = 5e-13
Identities = 118/519 (22%), Positives = 194/519 (37%), Gaps = 70/519 (13%)
Query: 271 APQNKILEGLEKLRHLDFLRYPVATQKDLASGAVPTNLKPSKIKQRADSKESLKATTKTA 330
A K+LEG E + F P + + L +P+ K+K K K+ +T
Sbjct: 400 AAYRKLLEGEEC--RIGFGPIPFSLPEGLPK--IPSVSTHIKVKSEEKIKVVEKSEKETV 455
Query: 331 V-----SKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESS 385
+ + EEV EE KEA+ E KE E++ E E+ + P E E
Sbjct: 456 IVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPE-- 513
Query: 386 EALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKK 445
K K +KE+ E K EK+E K + ++ + K++AK
Sbjct: 514 -------------KEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKS 560
Query: 446 EEKRKDTKPELKKISKPDLKPFTPEVRKTLYK--AKVPGRVKIDR--SRAIRGEKELSSE 501
+ K + E K S ++K +PE K+ K AK P K ++ E + +E
Sbjct: 561 PPEAKSPEKEEAK-SPAEVK--SPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAE 617
Query: 502 PQTPPAQKGTVPLPTISGHRELVLSSPEDL-TQDFEEMKREERALLAEQRDTGLGDKPFP 560
++P ++ P + SPE + EE K E+A E+ + +K
Sbjct: 618 AKSPVKEEAKSPAE---------VKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKS 668
Query: 561 LDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPE-----VPEEQGSKDRG---LDS 612
AE P A + + +KE+ PE V EE S ++ +
Sbjct: 669 PVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKE 728
Query: 613 GAETEE--EKDTWEEKKQREAERLPDRTEAREESEPE----VKEDVIEKAELEEMEEVHP 666
A+T E + EE K E + P++ + + PE KE+ A+ + P
Sbjct: 729 EAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSP 788
Query: 667 SDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFGGRELGLQGKAPEKETSLFLSSLTTPA 726
EE + KA+ ++ + P K P+ E K+P KE
Sbjct: 789 VKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEV----------KSPVKE-----EEKPQEV 833
Query: 727 GATEHVSYIQDETIPGYSETEQTISDEEIHDEPEERPAP 765
E ++E P +TE+ ++ +E P P
Sbjct: 834 KVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKP 872
Score = 74.7 bits (182), Expect = 1e-12
Identities = 142/694 (20%), Positives = 255/694 (36%), Gaps = 75/694 (10%)
Query: 1349 LKDRTSEQKKEPEPKDEVLQQKDKTLE-HKEVVEPKDTAIYQKDEALHVKNEAVKQQDKA 1407
L+ RT+E + KD + +Q+ + + H+ + AI Q D L + Q +
Sbjct: 325 LQARTTELEALKSTKDSLERQRSELEDRHQADIASYQEAIQQLDAELRNTKWEMAAQLRE 384
Query: 1408 LEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQK 1467
+ D + K LE ++ + + +P+ + K + E+K
Sbjct: 385 YQDLLNVKMALDIEIAAYRKLLEGEECRIGFGPIPFSLPEGLPKIPSVSTHIKVKS-EEK 443
Query: 1468 DKALEPKDKD---LEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLE 1524
K +E +K+ +E++ + E++ EE++K + + E K E E + E
Sbjct: 444 IKVVEKSEKETVIVEEQTEETQVTEEVTEEEEK----EAKEEEGKEEEGGEEEEAEGGEE 499
Query: 1525 QTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESL 1584
+T K+P + A +K+ S K++A +K+EA E ++ +E
Sbjct: 500 ET-KSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEA 558
Query: 1585 VQEDKTRKPKMLEEKSPEKVKAMEE-----KLEALL-------EKTKALGLEESLVQEGR 1632
+ + P+ E KSP +VK+ E+ K EA EK K+ EE+
Sbjct: 559 KSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEA 618
Query: 1633 AREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDT-SPEQDNRYWRGREDVAL 1691
+E+ +V + SPT+EE +K +P E+ SPE+
Sbjct: 619 KSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEK------------- 665
Query: 1692 EQDTYWRELSCERKVWFPHELDGQGARPHYTEERESTFLDEGPDDEQ-EVPLREHATRSP 1750
+ E K P + + + E+ +S +E E+ + P++E A
Sbjct: 666 AKSPVKAEAKSPEKAKSPVKAEAKS-----PEKAKSPVKEEAKSPEKAKSPVKEEAKSPE 720
Query: 1751 WASDFKDFQESSPQKGLEVERWLAESPVGLPPEEEDKLTRSPFEIISPPASPPEMVGQRV 1810
A + +P+K + A+SP E+ K ++ SP A P R
Sbjct: 721 KAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAK----TLDVKSPEAKTPAKEEARS 776
Query: 1811 PSAPGQE---SPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSPAPGPPTPA 1867
P+ E SP+ + P P + +D P + +P
Sbjct: 777 PADKFPEKAKSPVKEEVKSPEKAKSP------------LKEDAKAPEKEIPKKEEVKSPV 824
Query: 1868 PESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGEREEEGRAEAPDK 1927
E P V AE E P +P K K + ++EE + EAP
Sbjct: 825 KEEEKP----------QEVKVKEPPKKAEEEKAPATP--KTEEKKDSKKEEAPKKEAPKP 872
Query: 1928 SSHSSKVPEASK-SHATTEPEQTEPEQREPTPYPDERSFQYADIYEQMMLTGLGPACPTR 1986
K P K + E ++ E E ++ P P++ + ++ E +
Sbjct: 873 KVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVA-KK 931
Query: 1987 EPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSP 2020
EP A + KEAA + + E++ P
Sbjct: 932 EPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKP 965
Score = 65.1 bits (157), Expect = 9e-10
Identities = 166/773 (21%), Positives = 281/773 (36%), Gaps = 114/773 (14%)
Query: 1392 EALHVKNEAVKQQDKALEQKGRDLEQKDT---ALEQKDKALEPKDKDLEEKDKA-----L 1443
EA V +A++ + + + R L+ + T AL+ +LE + +LE++ +A
Sbjct: 302 EAAKVNTDAMRSAQEEITEYRRQLQARTTELEALKSTKDSLERQRSELEDRHQADIASYQ 361
Query: 1444 EQKDKIPEEKDKALEQKDTALEQKDKALEPK---DKDLEQKDRVLEQKE------KIPEE 1494
E ++ E + L + L K D ++ ++LE +E IP
Sbjct: 362 EAIQQLDAELRNTKWEMAAQLREYQDLLNVKMALDIEIAAYRKLLEGEECRIGFGPIPFS 421
Query: 1495 KDKALDQKVRSVEH--KAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALE 1552
+ L K+ SV K + ++ ++ ++T EQ + Q ++ E++ +A E
Sbjct: 422 LPEGLP-KIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKE 480
Query: 1553 QKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLE 1612
++ G+++E E E+E+ E++T+ P E SPEK K E
Sbjct: 481 EE----GKEEEGGE-------------EEEAEGGEEETKSPPAEEAASPEKEAKSPVKEE 523
Query: 1613 ALLEKTKALGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWE 1672
A K+ A E ++ E+EE +V + SP +EE + +P E
Sbjct: 524 A---KSPA---------EAKSPEKEEAK-SPAEVKSPEKAKSPAKEEAKSPPEAKSPEKE 570
Query: 1673 DTSPEQDNRYWRGREDVALEQDTYWRELSCERKVWFPHELDGQG---ARPHYTEERESTF 1729
+ + + + A E+ E K P + + + A+ EE +S
Sbjct: 571 EAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPA 630
Query: 1730 LDEGPDDEQEVPLREHATRSPWASDFKDFQESSPQKGLEVERWLAESP--VGLPPEEEDK 1787
+ P+ + P +E A A + + SP+K + A+SP P + E K
Sbjct: 631 EVKSPEKAKS-PTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAK 689
Query: 1788 LTRSPFEIISPPASPPEMVGQRVPSAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVP 1847
+ A PE + S +E+ P+ P +K E TP A P V
Sbjct: 690 SPEKAKSPVKEEAKSPE----KAKSPVKEEAKSPEKAKSP-VKEEAKTPE-KAKSP--VK 741
Query: 1848 KDRPLPPAPLSP--APGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPL 1905
++ P SP A +PE+ TPA + + E P
Sbjct: 742 EEAKSPEKAKSPEKAKTLDVKSPEAKTPAK---------EEARSPADKFPEKAKSPVKEE 792
Query: 1906 GKDYRKAEGEREEEGRA---EAPDKSSHSSKVPEASKSHATT---EPEQTEPEQREPTPY 1959
K KA+ +E+ +A E P K S V E K P++ E E+ TP
Sbjct: 793 VKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPK 852
Query: 1960 PDERSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSS 2019
+E+ + P +E P P KE A EK S
Sbjct: 853 TEEKKDSKKE------------EAPKKEAPK------PKVEEKKEPAV------EKPKES 888
Query: 2020 PISPKSLQSD----TPTFSYAALAGPTVPPRPEPGPSMEPSLTPP----AVPPRAPILSK 2071
+ K +++ PT A A V +P E + P A P P K
Sbjct: 889 KVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKK 948
Query: 2072 GPSPPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQS 2124
+P + + PK ++ DD T E K E+ EK + +
Sbjct: 949 EAAPEKK-DTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSST 1000
Score = 65.1 bits (157), Expect = 9e-10
Identities = 148/670 (22%), Positives = 243/670 (36%), Gaps = 96/670 (14%)
Query: 537 EMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMK-EKEL 595
E+ + L E+ G G PF L EG P T V + + V K EKE
Sbjct: 398 EIAAYRKLLEGEECRIGFGPIPFSL---PEGLPKIPSVSTHIKVKSEEKIKVVEKSEKET 454
Query: 596 VPEVPEEQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIEK 655
V + EEQ + + + E EE++ EE K+ E E E E E K E+
Sbjct: 455 V--IVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEG----GEEEEAEGGEEETKSPPAEE 508
Query: 656 AELEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFGGRELGL---QGKAPE 712
A E E P EE + +A+ ++ + P +V + +E + K+PE
Sbjct: 509 AASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPE 568
Query: 713 KETSLFLSSLTTPAGATEHVSYIQDETIPGYSETEQTISDEEIHDEPEERPAPPRFHT-S 771
KE + + + +P A S + +E P E +P + S
Sbjct: 569 KEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKS 628
Query: 772 TYDLPGPEGA---GPFEASQPADSAVP-----ATSGKVYGTPETELTYPTNIVAAPLAEE 823
++ PE A EA P + P + K + E P + AE
Sbjct: 629 PAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEA 688
Query: 824 EHVSSATS-ITECDKLSSFATSVAEDQSVASLTA-------PQTEETGKSSLLLDTVTSI 875
+ A S + E K A S ++++ + A +T E KS + + +
Sbjct: 689 KSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPE 748
Query: 876 PSSRTEATQGLDY-VPSAGT------ISPTSSLEEDKGFKSPPCEDFSVTGESEKRGEII 928
+ E + LD P A T SP E KSP E+ V + + +
Sbjct: 749 KAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKA--KSPVKEE--VKSPEKAKSPLK 804
Query: 929 GKGLSGERAVEEEEEETANVEMSEKLCSQYGTPVFSAPGHALHPGEPALGEAEERCLSPD 988
+ E+ + ++EE + V+ EK V P A PA + EE+ S
Sbjct: 805 EDAKAPEKEIPKKEEVKSPVKEEEK---PQEVKVKEPPKKAEEEKAPATPKTEEKKDSKK 861
Query: 989 DSTVKMASPPPSGPPSATHTPFHQSPVEEKSEPQDFQEADSWGDTKRTPGVGKEDAAEET 1048
+ K +P P VEEK EP + +S + K KE+A ++
Sbjct: 862 EEAPKKEAPKPK--------------VEEKKEPAVEKPKESKVEAK------KEEAEDKK 901
Query: 1049 VKPGPEEGTLE----KEEKVPPPRSPQAQEAPVNIDEGLTGCTIQLLPAQDKAIVFEIME 1104
P PE+ KE+ P ++ A++ P + +
Sbjct: 902 KVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEP------------------------DDAK 937
Query: 1105 AGEPTGPILGAEALPGGLRTLPQEPGKPQK----DEVLRYPDRSLSPEDAESLSVLSVPS 1160
A EP+ P EA P T ++ KP++ + + D++LS E ++ + + S
Sbjct: 938 AKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKS 997
Query: 1161 PDTANQEPTP 1170
T ++ P
Sbjct: 998 SSTDQKDSKP 1007
Score = 59.7 bits (143), Expect = 4e-08
Identities = 65/204 (31%), Positives = 92/204 (45%), Gaps = 24/204 (11%)
Query: 296 QKDLASGAVPTNLKPSKIKQRADSK----ESLKATTKTAVSKLAKREEVVEEGAKEARSE 351
+K+ V KP ++K + K E AT KT K +K+EE ++ A + + E
Sbjct: 816 KKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVE 875
Query: 352 LAKELA-------KTEKKAKESSEKP----PEK--PAKPERVKTESSEALKAEKRKLIKD 398
KE A K E K +E+ +K PEK PAK E VK ++ K E K D
Sbjct: 876 EKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVE-VKEDAKPKEKTEVAKKEPD 934
Query: 399 KVGKKHLKEKISKLE---EKKD-KEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKP 454
K + K E EKKD KE+K K E K + + ++++K +K+ K K K
Sbjct: 935 DAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKA 994
Query: 455 ELKKISKPDLKPFTPEVRKTLYKA 478
E K S D K P + T KA
Sbjct: 995 E--KSSSTDQKDSKPPEKATEDKA 1016
Score = 51.2 bits (121), Expect = 1e-05
Identities = 43/167 (25%), Positives = 73/167 (43%), Gaps = 29/167 (17%)
Query: 292 PVATQKDLASGAVPTNLKPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSE 351
P +K + P K K+ A+ K+ + K A +K+ EV E+ + ++E
Sbjct: 872 PKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKV----EVKEDAKPKEKTE 927
Query: 352 LAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISK 411
+AK K+ ++ K P KPA+ + E KK KE+ +K
Sbjct: 928 VAK------KEPDDAKAKEPSKPAEKKEAAPE------------------KKDTKEEKAK 963
Query: 412 LEEKKDKEKKEIKKERKELKKDEGR-KEEKKDAKKEEKRKDTKPELK 457
E+K K + + K++ K L K+ + K EK + +KD+KP K
Sbjct: 964 KPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEK 1010
Score = 48.9 bits (115), Expect = 7e-05
Identities = 75/347 (21%), Positives = 121/347 (34%), Gaps = 30/347 (8%)
Query: 2338 ECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAACPAWERGAWPEGA 2397
E + A E+ + E+ A G E + +PP A E E A P E P A
Sbjct: 473 EEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKE--AKSPVKEEAKSPAEA 530
Query: 2398 -----ERSSRPDTLLSPEQPVCPAGGSG-GPPSSASPEVEAGPQGCATEPRPHRGELSPS 2451
E + P + SPE+ PA PP + SPE E + A P + + SP+
Sbjct: 531 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEA-KSPAEVKSPEKAK-SPA 588
Query: 2452 FLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETP-----PTSASDS 2506
P + + V+ P P ++P P A
Sbjct: 589 KEEAKSPAEAKSPEKAKSPVK-------EEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSP 641
Query: 2507 GSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQ- 2565
++ S ++ E + S + +KA P P+ +
Sbjct: 642 TKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEE 701
Query: 2566 ---PDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASPARRL 2622
P+ SP + + PE S + EK K + ++P KAK A+ L
Sbjct: 702 AKSPEKAKSPVKEEA--KSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTL 759
Query: 2623 DLRGKRSPTPGKGPA-DRASRAPPRPRSTTSQVTPAEEKDGHSPMSK 2668
D++ + TP K A A + P + +S + + EK SP+ +
Sbjct: 760 DVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEK-AKSPLKE 805
Score = 37.7 bits (86), Expect = 0.16
Identities = 35/177 (19%), Positives = 67/177 (37%), Gaps = 11/177 (6%)
Query: 2494 VTDETPPTSASDSGSSQS---DSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSG 2550
VT+E + + G + + + EE S AE A +++ ++A +
Sbjct: 470 VTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAE 529
Query: 2551 THHPRP--GHDPPPLPQPDPRPSPPRPDVCMADPEGLSSESGRVE-----RLREKEKVQG 2603
P P + P+ SP + + + PE S E + + EK K
Sbjct: 530 AKSPEKEEAKSPAEVKSPEKAKSPAKEEA-KSPPEAKSPEKEEAKSPAEVKSPEKAKSPA 588
Query: 2604 RVGRRAPGKAKPASPARRLDLRGKRSPTPGKGPADRASRAPPRPRSTTSQVTPAEEK 2660
+ ++P +AK A+ +SP K P +++P +S +P +E+
Sbjct: 589 KEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEE 645
Score = 36.6 bits (83), Expect = 0.36
Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 2/85 (2%)
Query: 305 PTNLKPSKIKQRADSKESLKATTKTAVSKLAKREEV--VEEGAKEARSELAKELAKTEKK 362
P + K + + A+ KE+ T K K EE E AKE L+KE +K + +
Sbjct: 933 PDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAE 992
Query: 363 AKESSEKPPEKPAKPERVKTESSEA 387
E S +K +KP TE A
Sbjct: 993 KAEKSSSTDQKDSKPPEKATEDKAA 1017
Score = 33.1 bits (74), Expect = 4.0
Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 4/119 (3%)
Query: 2576 DVCMADPEGLSSESGRVERLREKEKVQG-RVGRRAPGKAKPASPARRLDLRGK---RSPT 2631
+V + + E G+ E E+E+ +G ++P + ASP + K +SP
Sbjct: 469 EVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPA 528
Query: 2632 PGKGPADRASRAPPRPRSTTSQVTPAEEKDGHSPMSKGLVNGLKAGPMALSSKGSSGAP 2690
K P +++P +S +PA+E+ P +K P + S + +P
Sbjct: 529 EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSP 587
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 103 bits (258), Expect = 2e-21
Identities = 179/823 (21%), Positives = 266/823 (32%), Gaps = 112/823 (13%)
Query: 1855 APLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEG 1914
AP S PTP E+ T P T + +E A+ P P + A
Sbjct: 188 APTSKVLAKPTPKAETTTKGPAL--TTPKEPTPTTPKEPASTT---PKEPTPTTIKSAPT 242
Query: 1915 EREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPT----PYPDERSFQYADI 1970
+E AP + + P+ T EP T P++ PT P P
Sbjct: 243 TPKEP----APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 298
Query: 1971 YEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDT 2030
E T PA T + P P + KE A T+ E ++P P
Sbjct: 299 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP---TTKEPAPTTPKEPAPTAPKK 355
Query: 2031 PTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVP-----PRAPILSKGPSPPLNGNILSCS 2085
P + PT P P P + EPS T P P AP +K P+P + +
Sbjct: 356 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS-APTT 414
Query: 2086 PDRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAH 2145
P SP+ + + + +K A P KE +P P P + P T
Sbjct: 415 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KEPAPTTPKEPAPTTTKKPAPTTPKE 473
Query: 2146 VSPPLDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALA 2205
+P P P P + L P P+ P+P P +
Sbjct: 474 PAPTTPKETAPTTPKKLTPTTP---EKLAPTTPEKPAPTTP------------EELAPTT 518
Query: 2206 PGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSP--GAPLLSNLPRPASPALSEGSSSEA 2263
P PT T +E T + ++ P+ P+P++P AP P P +P + ++ +
Sbjct: 519 PEEPTPTTPEEPAPTTPKAAAPNT-PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 577
Query: 2264 TTPVISSVAERFSPSLEA---------AEQESGELDPGMEPAAHSLWDLTPLSPAPPASL 2314
T P +P A E S D TP PAP
Sbjct: 578 TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 637
Query: 2315 DLALAPAPSLPGDMGDGILPCHL-ECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGPA 2373
+ PAP+ P G P L E + +KP+P ++ GPT T+ + P P
Sbjct: 638 E----PAPTTP----KGTAPTTLKEPAPTTPKKPAPKEL--APTTTKGPTSTTSDKPAPT 687
Query: 2374 PAKAENEEAAACPAWERGAWPEGAERSSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAG 2433
K E A P E A + + +PE P P ++ P
Sbjct: 688 TPK---ETAPTTP-------KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP----- 732
Query: 2434 PQGCATEPRPHRGELSPSFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCP 2493
T E +P P P ++++ + G TT P
Sbjct: 733 -----TTIHKSPDESTPELSAEPTPKALENSP---------------KEPGVPTTKTPAA 772
Query: 2494 VTDETPPTSASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHH 2553
E T+A D + + P T P +T E A +++ + V+ T
Sbjct: 773 TKPEM-TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTST-- 829
Query: 2554 PRPGHDPPPLPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKA 2613
D P + + P V ++E + + E K + R
Sbjct: 830 --TTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI--MNKPEETAKPKDRATNSKATTP 885
Query: 2614 KPASPARRLDLRGKRSPTPGKGPAD----RASRAPPRPRSTTS 2652
KP P + + PT K P R + P PR TS
Sbjct: 886 KPQKPT-----KAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS 923
Score = 77.8 bits (190), Expect = 1e-13
Identities = 150/706 (21%), Positives = 228/706 (32%), Gaps = 107/706 (15%)
Query: 2001 STKEAAAGRNTSAE------KELSSPISPKSLQSDTPTFSYAALAGPTVPPRP------E 2048
S KE + TSA+ K L+ P + P + PT P P E
Sbjct: 172 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKE 231
Query: 2049 PGPS------MEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSP----------- 2091
P P+ P P AP K P+P +P +P
Sbjct: 232 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 291
Query: 2092 -----SPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHV 2146
+PKE + + E E +P P P P+ A
Sbjct: 292 KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 351
Query: 2147 SPPLDSHLGPARPSLDFPASAFGFSSLQPAP--PQLPSPAEPRSAPCGSL--AFSGDRAL 2202
+P + P P+ P ++ +P+P P+ P+P +SAP + A + ++
Sbjct: 352 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 411
Query: 2203 ALAPGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSP--GAPLLSNLPRPASPALSEGSS 2260
P P+ T TK P+ + P+ P+P++P AP P P +P ++
Sbjct: 412 PTTPKEPSPT-------TTKEPA--PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 462
Query: 2261 SEATTPVISSVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAP 2320
++ P +P E A +L P L TP PAP +L
Sbjct: 463 TKKPAPTTPKEPAPTTPK-ETAPTTPKKLTP---TTPEKLAPTTPEKPAPTTPEEL---- 514
Query: 2321 APSLPGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENE 2380
AP+ P E + E+P+P + A N P E +P P E
Sbjct: 515 APTTPE-----------EPTPTTPEEPAP--TTPKAAAPNTPKEPAPTTPKEPAPTTPKE 561
Query: 2381 EAAACPAWERGAWPEGAERSSRPDTLL--SPEQPVCPAGGSGGPPSSASPEVEAGPQGCA 2438
A P P+G + P TL +P P PA P ++ P +
Sbjct: 562 PAPTTPKETAPTTPKG----TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 617
Query: 2439 TEPRPHRGELSPSFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDET 2498
T P+ +P+ P P + + +T + P T P P T +
Sbjct: 618 TTPK----GTAPTTPKEPAPTTPKEPAPTTP-----------KGTAPTTLKEPAPTTPKK 662
Query: 2499 P------PTSASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTH 2552
P PT+ S+ SD P +E T + E P A T
Sbjct: 663 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK------EPAPTTPKKPAPTTPETP 716
Query: 2553 HPRPGHDPPPLPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGK 2612
P P +P PD + PE LS+E + L K G + P
Sbjct: 717 PPTTSEVSTPTTTKEPTTIHKSPD--ESTPE-LSAEP-TPKALENSPKEPGVPTTKTPAA 772
Query: 2613 AKPASPARRLDLRGKRSPTPGKGPADRASRAPPRPRSTTSQVTPAE 2658
KP D +R A + +TT + T ++
Sbjct: 773 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESK 818
Score = 77.0 bits (188), Expect = 2e-13
Identities = 175/823 (21%), Positives = 268/823 (32%), Gaps = 177/823 (21%)
Query: 1848 KDRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAE-LEGGPYSPLG 1906
K +P P P+ G + P + T +++ V + + A+ + P P
Sbjct: 75 KKKPTPKPPVVDEAGSGLDNGDFKVTTPDT-STTQHNKVSTSPKITTAKPINPRPSLPPN 133
Query: 1907 KDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQ 1966
D K + +++ ++K TT ++T+ ++ S
Sbjct: 134 SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV 193
Query: 1967 YADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSL 2026
A + T GPA T + P P + KE SA P +PK
Sbjct: 194 LAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA------PTTPKE- 246
Query: 2027 QSDTPTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSP 2086
PT + +A PT P P P + EP+ T P P AP +K P+P + +
Sbjct: 247 --PAPTTTKSA---PTTPKEPAPTTTKEPAPTTPKEP--APTTTKEPAPTTTKSAPTTPK 299
Query: 2087 DRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQS-PSPPHPIPMGSPTLWPETEAH 2145
+ +PK K A P++ A + P P P P + A
Sbjct: 300 EPAPTTPK-----------------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 342
Query: 2146 VSPPLDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALA 2205
+P + P +P+ P P+ P+P P+
Sbjct: 343 TTPKEPAPTAPKKPA--------------PTTPKEPAPTTPKE----------------- 371
Query: 2206 PGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSP-GAPLLSNLPRPASPALSEGSSSEAT 2264
P P T TK PS + P+ P+P++ AP + P P + + S T
Sbjct: 372 PAPTT----------TKEPS--PTTPKEPAPTTTKSAPTTTKEPAPTT------TKSAPT 413
Query: 2265 TPVISSVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAPAPSL 2324
TP S P+ + EPA TP PAP + PAP+
Sbjct: 414 TPKEPSPTTTKEPAPTTPK----------EPAP-----TTPKKPAPTTPKE----PAPTT 454
Query: 2325 PGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAA 2384
P E + T+KP+P P E A P ET+P P + A
Sbjct: 455 PK-----------EPAPTTTKKPAP-TTPKEP-APTTPKETAPTTPKKLTPTTPEKLAPT 501
Query: 2385 CPAWERGAWPEG-AERSSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRP 2443
P PE A + T +PE+P P +A+P P T P+
Sbjct: 502 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT------PKAAAPNTPKEP--APTTPK- 552
Query: 2444 HRGELSPSFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETP-PTS 2502
E +P+ P P + + P T G P T + P PT+
Sbjct: 553 ---EPAPTTPKEPAPTTPKET-------------------APTTPKGTAPTTLKEPAPTT 590
Query: 2503 ASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRP----GH 2558
+ P T+E S T + + G K + P P G
Sbjct: 591 PKKPAPKEL---APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 647
Query: 2559 DPPPLPQPDPR-PSPPRP-DVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPA 2616
P L +P P P P P ++ +G +S + + P + P
Sbjct: 648 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS------------DKPAPTTPKETAPT 695
Query: 2617 SPARRLDLRGKRSPTPGKGPADRASRAPPRPRSTTSQVTPAEE 2659
+P + +PT K PA PP S S T +E
Sbjct: 696 TPK-------EPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE 731
Score = 72.0 bits (175), Expect = 8e-12
Identities = 100/437 (22%), Positives = 138/437 (31%), Gaps = 62/437 (14%)
Query: 1719 PHYTEERESTFLDEGPDDEQEVPLREHATRSPWASDFKDFQESSPQKGLEVERWLAESPV 1778
P T+E T P +E T+ P + K+ ++P+K + P
Sbjct: 397 PTTTKEPAPTTTKSAPTTPKEPS--PTTTKEPAPTTPKEPAPTTPKKPAPTT---PKEPA 451
Query: 1779 GLPPEEEDKLTRSPFEIISPPASPPEMVGQRVPSAPGQESPIPDPKLMPHM--KNEPTTP 1836
P+E T +P P + P+ P + +P KL P K PTTP
Sbjct: 452 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 511
Query: 1837 SWLADIPPWVPKDRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAE 1896
LA P + P P P PAP P A + P E
Sbjct: 512 EELAPTTP----EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 567
Query: 1897 LEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATT---EPEQTEPEQ 1953
E P +P G +E P K + P +K +T +P T P+
Sbjct: 568 KETAPTTPKG-----TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 622
Query: 1954 REPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSA 2013
PT P E + P P P G P L + A A
Sbjct: 623 TAPTT-PKEPA----------------PTTPKEPAPTTPKGTAPTTLK-EPAPTTPKKPA 664
Query: 2014 EKELSSPIS--PKSLQSDTPTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSK 2071
KEL+ + P S SD P + PT P P P +P+ T P PP
Sbjct: 665 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 724
Query: 2072 GPSPPLNGNILSCSPDRRSP-------------SPKESG----------RSHWDDSTSDS 2108
P+ + SPD +P SPKE G + + D
Sbjct: 725 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDK 784
Query: 2109 ELEKGAREQPEKEAQSP 2125
E+ R PE +P
Sbjct: 785 TTERDLRTTPETTTAAP 801
Score = 61.2 bits (147), Expect = 1e-08
Identities = 139/661 (21%), Positives = 203/661 (30%), Gaps = 128/661 (19%)
Query: 2058 TPPAVPPRAPILSKGPSPPLNGNILSCS---PDRRSPSPKESGRSHWDDSTSDSELEKGA 2114
T P + PI + PP + S + KE+ ++ ST E A
Sbjct: 114 TSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSA 173
Query: 2115 REQP--EKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFPASAFGFSS 2172
+E EK + P + PT ET P L + P + PAS
Sbjct: 174 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTK-GPALTTPKEPTPTTPKEPAST----- 227
Query: 2173 LQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQ 2232
P+ P+P +SAP P P T K P+ ++
Sbjct: 228 ----TPKEPTPTTIKSAPT-------------TPKEPAPTTTKSAPTTPKEPAPTTTKEP 270
Query: 2233 LPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFSPSLEAAEQESGELDPG 2292
P+ AP + P P + + S TTP + P+ +
Sbjct: 271 APTTPKEPAPTTTKEPAPTT------TKSAPTTPKEPAPTTPKKPAPTTPK--------- 315
Query: 2293 MEPAAHSLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLECSEAATEKPSPFQV 2352
EPA + + TP +P PA PAP+ P E + A +KP+P
Sbjct: 316 -EPAPTTPKEPTPTTPKEPAPT--TKEPAPTTPK-----------EPAPTAPKKPAP-TT 360
Query: 2353 PSEDCAANGPTETSPNPPGPAPAKAENEEAAACPAWERGAWPEGAERSSRPDTLLSPEQP 2412
P E P T+P P P K + PA S P T P
Sbjct: 361 PKE------PAPTTPKEPAPTTTKEPSPTTPKEPA--------PTTTKSAPTTTKEP--- 403
Query: 2413 VCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPPLPPSIDDRDLSTEEVR 2472
P P + P + T P+ E +P+ P P + + +T
Sbjct: 404 -APTTTKSAPTTPKEPSPTTTKEPAPTTPK----EPAPTTPKKPAPTTPKEPAPTTP--- 455
Query: 2473 LVGRGGRRRVGGPGTTGGPCPVTDETP-----------------PTSASDSGSSQSDSDV 2515
+ P TT P P T + P PT+ + +
Sbjct: 456 --------KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 507
Query: 2516 PPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRP 2575
P EE T E + + KA + P P P P P+P P
Sbjct: 508 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 567
Query: 2576 -DVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASPARRLDLR-GKRSPTPG 2633
+ P+G + + KE + AP + P + K +PT
Sbjct: 568 KETAPTTPKGTAPTT-------LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 620
Query: 2634 KG-----PADRASRAPPRPRSTTSQVT-PAEEKD-----GHSPMSKGLVNGLKAGPMALS 2682
KG P + A P P TT + T P K+ P K L GP + +
Sbjct: 621 KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTT 680
Query: 2683 S 2683
S
Sbjct: 681 S 681
Score = 55.5 bits (132), Expect = 7e-07
Identities = 173/797 (21%), Positives = 257/797 (32%), Gaps = 110/797 (13%)
Query: 873 TSIPSSRTEATQGLDYVPSAGTISPTSSLEEDKGFKSP---------PCEDFSVTGESEK 923
T P EA GLD T TS+ + +K SP P ++ K
Sbjct: 79 TPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSK 138
Query: 924 RGEIIGKGLSGERAVEEEEEETANVEMS----EKLCSQYGTP-VFSAPGHALHPGEPALG 978
+ ++ E VE +E T N + S EK S T + L P L
Sbjct: 139 ETSLT---VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA 195
Query: 979 E----AEERCLSPDDSTVKMASP-----PPSGPP---------SATHTPFHQSPVEEKSE 1020
+ AE P +T K +P P S P SA TP +P KS
Sbjct: 196 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 255
Query: 1021 PQDFQEADSWGDTKRTPGVGKEDAAEETVKPGP-EEGTLEKEEKVPPPRSPQAQEAPVNI 1079
P +E + P KE A T +P P + K P P +P+ + AP
Sbjct: 256 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPTTP 314
Query: 1080 DEGLTGCTIQLLPAQDKAIVFEIMEAGEPTGPILGAEALPGGLRTLPQEPGKPQKDEVLR 1139
E PA PT P E P T P+EP K+
Sbjct: 315 KE----------PA--------------PTTP---KEPTP----TTPKEPAPTTKE---- 339
Query: 1140 YPDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRWPEVSPEDTQSLSL 1199
P + E A + P+ TPK P T + E +P T+S
Sbjct: 340 -PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 398
Query: 1200 SEESPSKETSLDVSSKQLSPESLGTLQFGELNLGKEEMGHLMQAEDTSHHTAPMSVPEPH 1259
+ + P+ T+ + P T + KE A T AP + EP
Sbjct: 399 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAP-TTPKE------PAPTTPKKPAPTTPKEPA 451
Query: 1260 AATASPPTDGTTRYSAQTDITD--DSLDRKSPASSFSHSTPSGNGKYLP-----GAITSP 1312
T P TT+ A T + + +++ ++ TP+ K P A T+P
Sbjct: 452 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 511
Query: 1313 DEHI-LTPDSSFSKSPESLPGPALEDIAIKWEDKVPG---LKDRTSEQKKEPEP--KDEV 1366
+E TP+ +PE P P A K P K+ KEP P E
Sbjct: 512 EELAPTTPEEPTPTTPEE-PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 570
Query: 1367 LQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTA--LEQ 1424
K + EP T +K + K+ K K TA +
Sbjct: 571 APTTPKGTAPTTLKEPAPTT-PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 629
Query: 1425 KDKALEPKD--KDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKD 1482
+ PK+ + K+ P K ++ K DK
Sbjct: 630 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 689
Query: 1483 RVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQK-- 1540
+ E P+E +K + P T +E+ T K P H++ ++
Sbjct: 690 K--ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV---STPTTTKEPTTIHKSPDESTP 744
Query: 1541 DKVSEKKDQALEQKYWALG----QKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKML 1596
+ +E +ALE G + A + + ++ T+ E T PKM
Sbjct: 745 ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 804
Query: 1597 EEKSPEKVKAMEEKLEA 1613
+E + K E K+ A
Sbjct: 805 KETATTTEKTTESKITA 821
Score = 53.1 bits (126), Expect = 4e-06
Identities = 189/936 (20%), Positives = 307/936 (32%), Gaps = 125/936 (13%)
Query: 358 KTEKKAKESSEKPPE-------------KPAKPERVKTESSEALKAEKRKLIKDKVGKKH 404
K + K+ + KPP K P+ T+ ++ + K K +
Sbjct: 70 KKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPS 129
Query: 405 LKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDL 464
L +E KE E KE K+ D K++ ++K S DL
Sbjct: 130 LPPNSDTSKETSLTVNKETTVETKETTTTN--KQTSTDGKEKTTSAKETQSIEKTSAKDL 187
Query: 465 KPFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKELS-SEPQTPPAQKGTVPLPTISGHREL 523
P + + K KA+ + A+ KE + + P+ P + P PT
Sbjct: 188 APTSKVLAKPTPKAETT-----TKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT 242
Query: 524 VLSSPEDLTQDFEEMKREERALLAEQRDTGLGDK-PFPLDTAEEGPPSTAIQGTPPSVPG 582
P T +E A + K P P T E P +T T P P
Sbjct: 243 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 302
Query: 583 LGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEARE 642
K+ P P+E T +E K+ + P T +E
Sbjct: 303 ------PTTPKKPAPTTPKEPAPT---------TPKEPTPTTPKEPAPTTKEPAPTTPKE 347
Query: 643 ESEPEVKEDVIEKAELEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFGGR 702
+ K+ P+ +E T + +EP TP+ +
Sbjct: 348 PAPTAPKKPA-------------PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 394
Query: 703 ELGLQGKAPEKETSLFLSSLTTPAGATEHVSYIQDETIPGYSETEQTISDEEIHDEPEER 762
K P T+ S+ TTP + + T P E T + P+E
Sbjct: 395 SAPTTTKEPAPTTTK--SAPTTPKEPSPTTTKEPAPTTP--KEPAPTTPKKPAPTTPKE- 449
Query: 763 PAPPRFHTSTYDLPGPEGAGPFEASQPADSAVPATSGKVYGTPETELTYPTNIVAAPLAE 822
PAP +T P P + P + A P T + T +LT T AP
Sbjct: 450 PAP-----TTPKEPAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLTPTTPEKLAPTTP 503
Query: 823 EEHVSSATSITECDKLSSFATSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEA 882
E+ T ++L+ T + AP T + + + + P
Sbjct: 504 EKPAP-----TTPEELAP-TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT 557
Query: 883 TQGLDYVPSAGTISPTSSLEEDKGFKSPPCEDFSVTGESEKRGEIIGKGLSGERAVEEEE 942
T + +PT+ KG ++ + T + ++ +E
Sbjct: 558 TPKEPAPTTPKETAPTTP----KGTAPTTLKEPAPT--------------TPKKPAPKEL 599
Query: 943 EETANVEMSEKLCSQYG--TPVFSAPGHALHPGEPALGEAEERCLSPDDSTVKMASPPPS 1000
T E + C + TP +AP P EPA +E P +T K +P
Sbjct: 600 APTTTKEPTSTTCDKPAPTTPKGTAP---TTPKEPAPTTPKE----PAPTTPKGTAPTTL 652
Query: 1001 GPPSATHTPFHQSPVEEKSEPQDFQEADSWGDTKRTPGVGKEDAAEETVKPGPEEGTLEK 1060
P+ T TP + P ++ P + S K P KE A +P P
Sbjct: 653 KEPAPT-TP--KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT----- 704
Query: 1061 EEKVPPPRSPQAQEAPVNIDEGLTGCTIQLLPAQDKAIVFEIMEAGEPTGPILGAEALPG 1120
K P P +P+ P E T T + I ++ + + P L AE P
Sbjct: 705 -PKKPAPTTPETP--PPTTSEVSTPTTTKEPTT--------IHKSPDESTPELSAEPTPK 753
Query: 1121 GLRTLPQEPGKP-QKDEVLRYPDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQ 1179
L P+EPG P K P+ + + +D + L +P+T P T +
Sbjct: 754 ALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT-TPETTTAAPKMTKETATTTE 812
Query: 1180 YLHKDRWPEVSPEDTQSLSLSEESPSKETSLDVSSKQLSPE---SLGTLQFGELNLGKEE 1236
+ + + + T S + + +P K T+L ++ L+P+ + T+ E+ EE
Sbjct: 813 KTTESKITATTTQVT-STTTQDTTPFKITTLKTTT--LAPKVTTTKKTITTTEIMNKPEE 869
Query: 1237 MGHLMQAEDTSHHTAPMSVPEPHAATASPPTDGTTR 1272
S T P+P T +P +T+
Sbjct: 870 TAKPKDRATNSKAT----TPKPQKPTKAPKKPTSTK 901
Score = 42.4 bits (98), Expect = 0.007
Identities = 194/979 (19%), Positives = 306/979 (31%), Gaps = 150/979 (15%)
Query: 439 EKKDAKKEEKRKDTKPELKKISKP-------DLKPFTPEVRKTLYKAKVPGRVKIDRSRA 491
E KD KK +K P+ + + D K TP+ T + K+ S
Sbjct: 65 EVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHN-------KVSTSPK 117
Query: 492 IRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLAEQRD 551
I K ++ P PP T +++ ++E + + E T + ++ + + ++
Sbjct: 118 ITTAKPINPRPSLPP-NSDTSKETSLTVNKETTVETKETTTTN-KQTSTDGKEKTTSAKE 175
Query: 552 TGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKDRGLD 611
T +K D A P S + P + + KE P P+E S
Sbjct: 176 TQSIEKTSAKDLA---PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAST----- 227
Query: 612 SGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIEKAELEEMEEVHPSDEEE 671
E T + E P T++ + E ++ +E P+ +E
Sbjct: 228 --TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 285
Query: 672 EDATKAEGFYQKHMQEPLKVTPRSREAFGGRELGLQGKAPEKETSLFLSSLTTPAGATEH 731
T + +EP TP+ +E AP TTP T
Sbjct: 286 PAPTTTKSA-PTTPKEPAPTTPKKPAPTTPKE-----PAP-----------TTPKEPTPT 328
Query: 732 VSYIQDETIPGYSETEQTISDEEIHDEPEERPAPPRFHTSTYDLPGPEGAGPFEASQPAD 791
E P E T E P+ +PAP P+ P +PA
Sbjct: 329 TP---KEPAPTTKEPAPTTPKEPAPTAPK-KPAPTT----------PKEPAPTTPKEPA- 373
Query: 792 SAVPATSGKVYGTPETELTYPTNIVAAPLAEEEHVSSAT-SITECDKLSSFATSVAEDQS 850
P T+ + T E PT +AP +E + T S K S T+ +
Sbjct: 374 ---PTTTKEPSPTTPKEPA-PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 429
Query: 851 VASLTAPQTEETGKSSLLLDTVTSIPSSRTEATQGLDYVPSAGTISPTSSLEEDKGFKSP 910
AP T + + + + P T T P + ++ +P
Sbjct: 430 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT----------TKKPAPTTPKEPAPTTP 479
Query: 911 PCEDFSVTGESEKRGEIIGKGLSGERAVEEEEEETANVEMSEKLCSQYGTPVFSAPGHAL 970
+ETA +KL TP AP
Sbjct: 480 --------------------------------KETAPTT-PKKLTPT--TPEKLAP---T 501
Query: 971 HPGEPALGEAEERCLSPDDSTVKMASPPPSGPPSATHTPFHQSPVEEKSEPQDFQEADSW 1030
P +PA EE L+P P P+ P T + EP +
Sbjct: 502 TPEKPAPTTPEE--LAPTTPE----EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA 555
Query: 1031 GDTKRTPGVGKEDAAEETVKPGPEEGTLEKEEKVPPPRSPQAQEAPVNIDEGLTGCTIQL 1090
T + P T G TL++ P + + AP E + +
Sbjct: 556 PTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 615
Query: 1091 LPAQDKAIVFEIMEAGEPTGPILGAEALPGGL------RTLPQEPGKPQKDEV----LRY 1140
P K + PT P A P G P P KP E+ +
Sbjct: 616 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG 675
Query: 1141 PDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRWPEVSPEDTQSLS-- 1198
P + S + A + + P+ TPK P T PE P T +S
Sbjct: 676 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT---------PETPPPTTSEVSTP 726
Query: 1199 -LSEESPSKETSLDVSSKQLSPE-SLGTLQFGELNLGKEEMGHLMQAEDTSHHTAPMSVP 1256
++E + S D S+ +LS E + L+ G + TA
Sbjct: 727 TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTT 786
Query: 1257 EPHAATASPPTDGTTRYSAQTDITDDSLDRKSPASSFSHSTPSGNGKYLPGAITSPDEHI 1316
E T T + + +T T + ++ + T + P IT+
Sbjct: 787 ERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTT 846
Query: 1317 LTPDSSFSK----SPESLPGPALEDIAIKWEDKVPGLKDRTSE-QKKEPEPKDEVLQQKD 1371
L P + +K + E + P E+ A K +D+ K T + QK PK +K
Sbjct: 847 LAPKVTTTKKTITTTEIMNKP--EETA-KPKDRATNSKATTPKPQKPTKAPKKPTSTKKP 903
Query: 1372 KTLEHKEVVEPKDTAIYQK 1390
KT+ V +PK T +K
Sbjct: 904 KTM--PRVRKPKTTPTPRK 920
Score = 36.6 bits (83), Expect = 0.36
Identities = 75/323 (23%), Positives = 105/323 (32%), Gaps = 47/323 (14%)
Query: 295 TQKDLASGAVPTNLKPSKIKQRADS--KESLKATTKTAVSKLAKR------EEVVEEGAK 346
T + + P L P+ ++ + +E T K A K +E K
Sbjct: 501 TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK 560
Query: 347 EARSELAKELAKTEKKA------KESSEKPPEKPAKPERVKTESSE--ALKAEKRKLIKD 398
E KE A T K KE + P+KPA E T + E + +K
Sbjct: 561 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 620
Query: 399 KVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTK-PELK 457
K G K K+ K K+ KK A KE TK P
Sbjct: 621 K-GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 679
Query: 458 KISKPDLKPFTP-EVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPT 516
KP P TP E T K P K K + P+TPP V PT
Sbjct: 680 TSDKP--APTTPKETAPTTPKEPAPTTPK----------KPAPTTPETPPPTTSEVSTPT 727
Query: 517 ISGHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAI-QG 575
+ + SP++ T + L AE L + P E G P+T
Sbjct: 728 TTKEPTTIHKSPDESTPE----------LSAEPTPKALENSP-----KEPGVPTTKTPAA 772
Query: 576 TPPSVPGLGQEEHVMKEKELVPE 598
T P + +++ ++ PE
Sbjct: 773 TKPEMTTTAKDKTTERDLRTTPE 795
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 103 bits (258), Expect = 2e-21
Identities = 179/823 (21%), Positives = 266/823 (32%), Gaps = 112/823 (13%)
Query: 1855 APLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEG 1914
AP S PTP E+ T P T + +E A+ P P + A
Sbjct: 229 APTSKVLAKPTPKAETTTKGPAL--TTPKEPTPTTPKEPASTT---PKEPTPTTIKSAPT 283
Query: 1915 EREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPT----PYPDERSFQYADI 1970
+E AP + + P+ T EP T P++ PT P P
Sbjct: 284 TPKEP----APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 339
Query: 1971 YEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDT 2030
E T PA T + P P + KE A T+ E ++P P
Sbjct: 340 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP---TTKEPAPTTPKEPAPTAPKK 396
Query: 2031 PTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVP-----PRAPILSKGPSPPLNGNILSCS 2085
P + PT P P P + EPS T P P AP +K P+P + +
Sbjct: 397 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS-APTT 455
Query: 2086 PDRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAH 2145
P SP+ + + + +K A P KE +P P P + P T
Sbjct: 456 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KEPAPTTPKEPAPTTTKKPAPTTPKE 514
Query: 2146 VSPPLDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALA 2205
+P P P P + L P P+ P+P P +
Sbjct: 515 PAPTTPKETAPTTPKKLTPTTP---EKLAPTTPEKPAPTTP------------EELAPTT 559
Query: 2206 PGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSP--GAPLLSNLPRPASPALSEGSSSEA 2263
P PT T +E T + ++ P+ P+P++P AP P P +P + ++ +
Sbjct: 560 PEEPTPTTPEEPAPTTPKAAAPNT-PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 618
Query: 2264 TTPVISSVAERFSPSLEA---------AEQESGELDPGMEPAAHSLWDLTPLSPAPPASL 2314
T P +P A E S D TP PAP
Sbjct: 619 TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 678
Query: 2315 DLALAPAPSLPGDMGDGILPCHL-ECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGPA 2373
+ PAP+ P G P L E + +KP+P ++ GPT T+ + P P
Sbjct: 679 E----PAPTTP----KGTAPTTLKEPAPTTPKKPAPKEL--APTTTKGPTSTTSDKPAPT 728
Query: 2374 PAKAENEEAAACPAWERGAWPEGAERSSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAG 2433
K E A P E A + + +PE P P ++ P
Sbjct: 729 TPK---ETAPTTP-------KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP----- 773
Query: 2434 PQGCATEPRPHRGELSPSFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCP 2493
T E +P P P ++++ + G TT P
Sbjct: 774 -----TTIHKSPDESTPELSAEPTPKALENSP---------------KEPGVPTTKTPAA 813
Query: 2494 VTDETPPTSASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHH 2553
E T+A D + + P T P +T E A +++ + V+ T
Sbjct: 814 TKPEM-TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTST-- 870
Query: 2554 PRPGHDPPPLPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKA 2613
D P + + P V ++E + + E K + R
Sbjct: 871 --TTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI--MNKPEETAKPKDRATNSKATTP 926
Query: 2614 KPASPARRLDLRGKRSPTPGKGPAD----RASRAPPRPRSTTS 2652
KP P + + PT K P R + P PR TS
Sbjct: 927 KPQKPT-----KAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS 964
Score = 77.8 bits (190), Expect = 1e-13
Identities = 150/706 (21%), Positives = 228/706 (32%), Gaps = 107/706 (15%)
Query: 2001 STKEAAAGRNTSAE------KELSSPISPKSLQSDTPTFSYAALAGPTVPPRP------E 2048
S KE + TSA+ K L+ P + P + PT P P E
Sbjct: 213 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKE 272
Query: 2049 PGPS------MEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSP----------- 2091
P P+ P P AP K P+P +P +P
Sbjct: 273 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 332
Query: 2092 -----SPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHV 2146
+PKE + + E E +P P P P+ A
Sbjct: 333 KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 392
Query: 2147 SPPLDSHLGPARPSLDFPASAFGFSSLQPAP--PQLPSPAEPRSAPCGSL--AFSGDRAL 2202
+P + P P+ P ++ +P+P P+ P+P +SAP + A + ++
Sbjct: 393 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 452
Query: 2203 ALAPGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSP--GAPLLSNLPRPASPALSEGSS 2260
P P+ T TK P+ + P+ P+P++P AP P P +P ++
Sbjct: 453 PTTPKEPSPT-------TTKEPA--PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 503
Query: 2261 SEATTPVISSVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAP 2320
++ P +P E A +L P L TP PAP +L
Sbjct: 504 TKKPAPTTPKEPAPTTPK-ETAPTTPKKLTP---TTPEKLAPTTPEKPAPTTPEEL---- 555
Query: 2321 APSLPGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENE 2380
AP+ P E + E+P+P + A N P E +P P E
Sbjct: 556 APTTPE-----------EPTPTTPEEPAP--TTPKAAAPNTPKEPAPTTPKEPAPTTPKE 602
Query: 2381 EAAACPAWERGAWPEGAERSSRPDTLL--SPEQPVCPAGGSGGPPSSASPEVEAGPQGCA 2438
A P P+G + P TL +P P PA P ++ P +
Sbjct: 603 PAPTTPKETAPTTPKG----TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 658
Query: 2439 TEPRPHRGELSPSFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDET 2498
T P+ +P+ P P + + +T + P T P P T +
Sbjct: 659 TTPK----GTAPTTPKEPAPTTPKEPAPTTP-----------KGTAPTTLKEPAPTTPKK 703
Query: 2499 P------PTSASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTH 2552
P PT+ S+ SD P +E T + E P A T
Sbjct: 704 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK------EPAPTTPKKPAPTTPETP 757
Query: 2553 HPRPGHDPPPLPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGK 2612
P P +P PD + PE LS+E + L K G + P
Sbjct: 758 PPTTSEVSTPTTTKEPTTIHKSPD--ESTPE-LSAEP-TPKALENSPKEPGVPTTKTPAA 813
Query: 2613 AKPASPARRLDLRGKRSPTPGKGPADRASRAPPRPRSTTSQVTPAE 2658
KP D +R A + +TT + T ++
Sbjct: 814 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESK 859
Score = 77.0 bits (188), Expect = 2e-13
Identities = 175/823 (21%), Positives = 268/823 (32%), Gaps = 177/823 (21%)
Query: 1848 KDRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAE-LEGGPYSPLG 1906
K +P P P+ G + P + T +++ V + + A+ + P P
Sbjct: 116 KKKPTPKPPVVDEAGSGLDNGDFKVTTPDT-STTQHNKVSTSPKITTAKPINPRPSLPPN 174
Query: 1907 KDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQ 1966
D K + +++ ++K TT ++T+ ++ S
Sbjct: 175 SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV 234
Query: 1967 YADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSL 2026
A + T GPA T + P P + KE SA P +PK
Sbjct: 235 LAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA------PTTPKE- 287
Query: 2027 QSDTPTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSP 2086
PT + +A PT P P P + EP+ T P P AP +K P+P + +
Sbjct: 288 --PAPTTTKSA---PTTPKEPAPTTTKEPAPTTPKEP--APTTTKEPAPTTTKSAPTTPK 340
Query: 2087 DRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQS-PSPPHPIPMGSPTLWPETEAH 2145
+ +PK K A P++ A + P P P P + A
Sbjct: 341 EPAPTTPK-----------------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 383
Query: 2146 VSPPLDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALA 2205
+P + P +P+ P P+ P+P P+
Sbjct: 384 TTPKEPAPTAPKKPA--------------PTTPKEPAPTTPKE----------------- 412
Query: 2206 PGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSP-GAPLLSNLPRPASPALSEGSSSEAT 2264
P P T TK PS + P+ P+P++ AP + P P + + S T
Sbjct: 413 PAPTT----------TKEPS--PTTPKEPAPTTTKSAPTTTKEPAPTT------TKSAPT 454
Query: 2265 TPVISSVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAPAPSL 2324
TP S P+ + EPA TP PAP + PAP+
Sbjct: 455 TPKEPSPTTTKEPAPTTPK----------EPAP-----TTPKKPAPTTPKE----PAPTT 495
Query: 2325 PGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAA 2384
P E + T+KP+P P E A P ET+P P + A
Sbjct: 496 PK-----------EPAPTTTKKPAP-TTPKEP-APTTPKETAPTTPKKLTPTTPEKLAPT 542
Query: 2385 CPAWERGAWPEG-AERSSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRP 2443
P PE A + T +PE+P P +A+P P T P+
Sbjct: 543 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT------PKAAAPNTPKEP--APTTPK- 593
Query: 2444 HRGELSPSFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETP-PTS 2502
E +P+ P P + + P T G P T + P PT+
Sbjct: 594 ---EPAPTTPKEPAPTTPKET-------------------APTTPKGTAPTTLKEPAPTT 631
Query: 2503 ASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRP----GH 2558
+ P T+E S T + + G K + P P G
Sbjct: 632 PKKPAPKEL---APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 688
Query: 2559 DPPPLPQPDPR-PSPPRP-DVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPA 2616
P L +P P P P P ++ +G +S + + P + P
Sbjct: 689 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS------------DKPAPTTPKETAPT 736
Query: 2617 SPARRLDLRGKRSPTPGKGPADRASRAPPRPRSTTSQVTPAEE 2659
+P + +PT K PA PP S S T +E
Sbjct: 737 TPK-------EPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE 772
Score = 72.0 bits (175), Expect = 8e-12
Identities = 100/437 (22%), Positives = 138/437 (31%), Gaps = 62/437 (14%)
Query: 1719 PHYTEERESTFLDEGPDDEQEVPLREHATRSPWASDFKDFQESSPQKGLEVERWLAESPV 1778
P T+E T P +E T+ P + K+ ++P+K + P
Sbjct: 438 PTTTKEPAPTTTKSAPTTPKEPS--PTTTKEPAPTTPKEPAPTTPKKPAPTT---PKEPA 492
Query: 1779 GLPPEEEDKLTRSPFEIISPPASPPEMVGQRVPSAPGQESPIPDPKLMPHM--KNEPTTP 1836
P+E T +P P + P+ P + +P KL P K PTTP
Sbjct: 493 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 552
Query: 1837 SWLADIPPWVPKDRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAE 1896
LA P + P P P PAP P A + P E
Sbjct: 553 EELAPTTP----EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 608
Query: 1897 LEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATT---EPEQTEPEQ 1953
E P +P G +E P K + P +K +T +P T P+
Sbjct: 609 KETAPTTPKG-----TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 663
Query: 1954 REPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSA 2013
PT P E + P P P G P L + A A
Sbjct: 664 TAPTT-PKEPA----------------PTTPKEPAPTTPKGTAPTTLK-EPAPTTPKKPA 705
Query: 2014 EKELSSPIS--PKSLQSDTPTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSK 2071
KEL+ + P S SD P + PT P P P +P+ T P PP
Sbjct: 706 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 765
Query: 2072 GPSPPLNGNILSCSPDRRSP-------------SPKESG----------RSHWDDSTSDS 2108
P+ + SPD +P SPKE G + + D
Sbjct: 766 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDK 825
Query: 2109 ELEKGAREQPEKEAQSP 2125
E+ R PE +P
Sbjct: 826 TTERDLRTTPETTTAAP 842
Score = 61.2 bits (147), Expect = 1e-08
Identities = 139/661 (21%), Positives = 203/661 (30%), Gaps = 128/661 (19%)
Query: 2058 TPPAVPPRAPILSKGPSPPLNGNILSCS---PDRRSPSPKESGRSHWDDSTSDSELEKGA 2114
T P + PI + PP + S + KE+ ++ ST E A
Sbjct: 155 TSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSA 214
Query: 2115 REQP--EKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFPASAFGFSS 2172
+E EK + P + PT ET P L + P + PAS
Sbjct: 215 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTK-GPALTTPKEPTPTTPKEPAST----- 268
Query: 2173 LQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQ 2232
P+ P+P +SAP P P T K P+ ++
Sbjct: 269 ----TPKEPTPTTIKSAPT-------------TPKEPAPTTTKSAPTTPKEPAPTTTKEP 311
Query: 2233 LPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFSPSLEAAEQESGELDPG 2292
P+ AP + P P + + S TTP + P+ +
Sbjct: 312 APTTPKEPAPTTTKEPAPTT------TKSAPTTPKEPAPTTPKKPAPTTPK--------- 356
Query: 2293 MEPAAHSLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLECSEAATEKPSPFQV 2352
EPA + + TP +P PA PAP+ P E + A +KP+P
Sbjct: 357 -EPAPTTPKEPTPTTPKEPAPT--TKEPAPTTPK-----------EPAPTAPKKPAP-TT 401
Query: 2353 PSEDCAANGPTETSPNPPGPAPAKAENEEAAACPAWERGAWPEGAERSSRPDTLLSPEQP 2412
P E P T+P P P K + PA S P T P
Sbjct: 402 PKE------PAPTTPKEPAPTTTKEPSPTTPKEPA--------PTTTKSAPTTTKEP--- 444
Query: 2413 VCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPPLPPSIDDRDLSTEEVR 2472
P P + P + T P+ E +P+ P P + + +T
Sbjct: 445 -APTTTKSAPTTPKEPSPTTTKEPAPTTPK----EPAPTTPKKPAPTTPKEPAPTTP--- 496
Query: 2473 LVGRGGRRRVGGPGTTGGPCPVTDETP-----------------PTSASDSGSSQSDSDV 2515
+ P TT P P T + P PT+ + +
Sbjct: 497 --------KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 548
Query: 2516 PPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRP 2575
P EE T E + + KA + P P P P P+P P
Sbjct: 549 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 608
Query: 2576 -DVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASPARRLDLR-GKRSPTPG 2633
+ P+G + + KE + AP + P + K +PT
Sbjct: 609 KETAPTTPKGTAPTT-------LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 661
Query: 2634 KG-----PADRASRAPPRPRSTTSQVT-PAEEKD-----GHSPMSKGLVNGLKAGPMALS 2682
KG P + A P P TT + T P K+ P K L GP + +
Sbjct: 662 KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTT 721
Query: 2683 S 2683
S
Sbjct: 722 S 722
Score = 55.5 bits (132), Expect = 7e-07
Identities = 173/797 (21%), Positives = 257/797 (32%), Gaps = 110/797 (13%)
Query: 873 TSIPSSRTEATQGLDYVPSAGTISPTSSLEEDKGFKSP---------PCEDFSVTGESEK 923
T P EA GLD T TS+ + +K SP P ++ K
Sbjct: 120 TPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSK 179
Query: 924 RGEIIGKGLSGERAVEEEEEETANVEMS----EKLCSQYGTP-VFSAPGHALHPGEPALG 978
+ ++ E VE +E T N + S EK S T + L P L
Sbjct: 180 ETSLT---VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA 236
Query: 979 E----AEERCLSPDDSTVKMASP-----PPSGPP---------SATHTPFHQSPVEEKSE 1020
+ AE P +T K +P P S P SA TP +P KS
Sbjct: 237 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 296
Query: 1021 PQDFQEADSWGDTKRTPGVGKEDAAEETVKPGP-EEGTLEKEEKVPPPRSPQAQEAPVNI 1079
P +E + P KE A T +P P + K P P +P+ + AP
Sbjct: 297 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPTTP 355
Query: 1080 DEGLTGCTIQLLPAQDKAIVFEIMEAGEPTGPILGAEALPGGLRTLPQEPGKPQKDEVLR 1139
E PA PT P E P T P+EP K+
Sbjct: 356 KE----------PA--------------PTTP---KEPTP----TTPKEPAPTTKE---- 380
Query: 1140 YPDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRWPEVSPEDTQSLSL 1199
P + E A + P+ TPK P T + E +P T+S
Sbjct: 381 -PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 439
Query: 1200 SEESPSKETSLDVSSKQLSPESLGTLQFGELNLGKEEMGHLMQAEDTSHHTAPMSVPEPH 1259
+ + P+ T+ + P T + KE A T AP + EP
Sbjct: 440 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAP-TTPKE------PAPTTPKKPAPTTPKEPA 492
Query: 1260 AATASPPTDGTTRYSAQTDITD--DSLDRKSPASSFSHSTPSGNGKYLP-----GAITSP 1312
T P TT+ A T + + +++ ++ TP+ K P A T+P
Sbjct: 493 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 552
Query: 1313 DEHI-LTPDSSFSKSPESLPGPALEDIAIKWEDKVPG---LKDRTSEQKKEPEP--KDEV 1366
+E TP+ +PE P P A K P K+ KEP P E
Sbjct: 553 EELAPTTPEEPTPTTPEE-PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 611
Query: 1367 LQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTA--LEQ 1424
K + EP T +K + K+ K K TA +
Sbjct: 612 APTTPKGTAPTTLKEPAPTT-PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 670
Query: 1425 KDKALEPKD--KDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKD 1482
+ PK+ + K+ P K ++ K DK
Sbjct: 671 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 730
Query: 1483 RVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQK-- 1540
+ E P+E +K + P T +E+ T K P H++ ++
Sbjct: 731 K--ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV---STPTTTKEPTTIHKSPDESTP 785
Query: 1541 DKVSEKKDQALEQKYWALG----QKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKML 1596
+ +E +ALE G + A + + ++ T+ E T PKM
Sbjct: 786 ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 845
Query: 1597 EEKSPEKVKAMEEKLEA 1613
+E + K E K+ A
Sbjct: 846 KETATTTEKTTESKITA 862
Score = 53.1 bits (126), Expect = 4e-06
Identities = 189/936 (20%), Positives = 307/936 (32%), Gaps = 125/936 (13%)
Query: 358 KTEKKAKESSEKPPE-------------KPAKPERVKTESSEALKAEKRKLIKDKVGKKH 404
K + K+ + KPP K P+ T+ ++ + K K +
Sbjct: 111 KKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPS 170
Query: 405 LKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDL 464
L +E KE E KE K+ D K++ ++K S DL
Sbjct: 171 LPPNSDTSKETSLTVNKETTVETKETTTTN--KQTSTDGKEKTTSAKETQSIEKTSAKDL 228
Query: 465 KPFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKELS-SEPQTPPAQKGTVPLPTISGHREL 523
P + + K KA+ + A+ KE + + P+ P + P PT
Sbjct: 229 APTSKVLAKPTPKAETT-----TKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT 283
Query: 524 VLSSPEDLTQDFEEMKREERALLAEQRDTGLGDK-PFPLDTAEEGPPSTAIQGTPPSVPG 582
P T +E A + K P P T E P +T T P P
Sbjct: 284 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 343
Query: 583 LGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEARE 642
K+ P P+E T +E K+ + P T +E
Sbjct: 344 ------PTTPKKPAPTTPKEPAPT---------TPKEPTPTTPKEPAPTTKEPAPTTPKE 388
Query: 643 ESEPEVKEDVIEKAELEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFGGR 702
+ K+ P+ +E T + +EP TP+ +
Sbjct: 389 PAPTAPKKPA-------------PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 435
Query: 703 ELGLQGKAPEKETSLFLSSLTTPAGATEHVSYIQDETIPGYSETEQTISDEEIHDEPEER 762
K P T+ S+ TTP + + T P E T + P+E
Sbjct: 436 SAPTTTKEPAPTTTK--SAPTTPKEPSPTTTKEPAPTTP--KEPAPTTPKKPAPTTPKE- 490
Query: 763 PAPPRFHTSTYDLPGPEGAGPFEASQPADSAVPATSGKVYGTPETELTYPTNIVAAPLAE 822
PAP +T P P + P + A P T + T +LT T AP
Sbjct: 491 PAP-----TTPKEPAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLTPTTPEKLAPTTP 544
Query: 823 EEHVSSATSITECDKLSSFATSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEA 882
E+ T ++L+ T + AP T + + + + P
Sbjct: 545 EKPAP-----TTPEELAP-TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT 598
Query: 883 TQGLDYVPSAGTISPTSSLEEDKGFKSPPCEDFSVTGESEKRGEIIGKGLSGERAVEEEE 942
T + +PT+ KG ++ + T + ++ +E
Sbjct: 599 TPKEPAPTTPKETAPTTP----KGTAPTTLKEPAPT--------------TPKKPAPKEL 640
Query: 943 EETANVEMSEKLCSQYG--TPVFSAPGHALHPGEPALGEAEERCLSPDDSTVKMASPPPS 1000
T E + C + TP +AP P EPA +E P +T K +P
Sbjct: 641 APTTTKEPTSTTCDKPAPTTPKGTAP---TTPKEPAPTTPKE----PAPTTPKGTAPTTL 693
Query: 1001 GPPSATHTPFHQSPVEEKSEPQDFQEADSWGDTKRTPGVGKEDAAEETVKPGPEEGTLEK 1060
P+ T TP + P ++ P + S K P KE A +P P
Sbjct: 694 KEPAPT-TP--KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT----- 745
Query: 1061 EEKVPPPRSPQAQEAPVNIDEGLTGCTIQLLPAQDKAIVFEIMEAGEPTGPILGAEALPG 1120
K P P +P+ P E T T + I ++ + + P L AE P
Sbjct: 746 -PKKPAPTTPETP--PPTTSEVSTPTTTKEPTT--------IHKSPDESTPELSAEPTPK 794
Query: 1121 GLRTLPQEPGKP-QKDEVLRYPDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQ 1179
L P+EPG P K P+ + + +D + L +P+T P T +
Sbjct: 795 ALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT-TPETTTAAPKMTKETATTTE 853
Query: 1180 YLHKDRWPEVSPEDTQSLSLSEESPSKETSLDVSSKQLSPE---SLGTLQFGELNLGKEE 1236
+ + + + T S + + +P K T+L ++ L+P+ + T+ E+ EE
Sbjct: 854 KTTESKITATTTQVT-STTTQDTTPFKITTLKTTT--LAPKVTTTKKTITTTEIMNKPEE 910
Query: 1237 MGHLMQAEDTSHHTAPMSVPEPHAATASPPTDGTTR 1272
S T P+P T +P +T+
Sbjct: 911 TAKPKDRATNSKAT----TPKPQKPTKAPKKPTSTK 942
Score = 42.4 bits (98), Expect = 0.007
Identities = 194/979 (19%), Positives = 306/979 (31%), Gaps = 150/979 (15%)
Query: 439 EKKDAKKEEKRKDTKPELKKISKP-------DLKPFTPEVRKTLYKAKVPGRVKIDRSRA 491
E KD KK +K P+ + + D K TP+ T + K+ S
Sbjct: 106 EVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHN-------KVSTSPK 158
Query: 492 IRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLAEQRD 551
I K ++ P PP T +++ ++E + + E T + ++ + + ++
Sbjct: 159 ITTAKPINPRPSLPP-NSDTSKETSLTVNKETTVETKETTTTN-KQTSTDGKEKTTSAKE 216
Query: 552 TGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKDRGLD 611
T +K D A P S + P + + KE P P+E S
Sbjct: 217 TQSIEKTSAKDLA---PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAST----- 268
Query: 612 SGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIEKAELEEMEEVHPSDEEE 671
E T + E P T++ + E ++ +E P+ +E
Sbjct: 269 --TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 326
Query: 672 EDATKAEGFYQKHMQEPLKVTPRSREAFGGRELGLQGKAPEKETSLFLSSLTTPAGATEH 731
T + +EP TP+ +E AP TTP T
Sbjct: 327 PAPTTTKSA-PTTPKEPAPTTPKKPAPTTPKE-----PAP-----------TTPKEPTPT 369
Query: 732 VSYIQDETIPGYSETEQTISDEEIHDEPEERPAPPRFHTSTYDLPGPEGAGPFEASQPAD 791
E P E T E P+ +PAP P+ P +PA
Sbjct: 370 TP---KEPAPTTKEPAPTTPKEPAPTAPK-KPAPTT----------PKEPAPTTPKEPA- 414
Query: 792 SAVPATSGKVYGTPETELTYPTNIVAAPLAEEEHVSSAT-SITECDKLSSFATSVAEDQS 850
P T+ + T E PT +AP +E + T S K S T+ +
Sbjct: 415 ---PTTTKEPSPTTPKEPA-PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 470
Query: 851 VASLTAPQTEETGKSSLLLDTVTSIPSSRTEATQGLDYVPSAGTISPTSSLEEDKGFKSP 910
AP T + + + + P T T P + ++ +P
Sbjct: 471 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT----------TKKPAPTTPKEPAPTTP 520
Query: 911 PCEDFSVTGESEKRGEIIGKGLSGERAVEEEEEETANVEMSEKLCSQYGTPVFSAPGHAL 970
+ETA +KL TP AP
Sbjct: 521 --------------------------------KETAPTT-PKKLTPT--TPEKLAP---T 542
Query: 971 HPGEPALGEAEERCLSPDDSTVKMASPPPSGPPSATHTPFHQSPVEEKSEPQDFQEADSW 1030
P +PA EE L+P P P+ P T + EP +
Sbjct: 543 TPEKPAPTTPEE--LAPTTPE----EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA 596
Query: 1031 GDTKRTPGVGKEDAAEETVKPGPEEGTLEKEEKVPPPRSPQAQEAPVNIDEGLTGCTIQL 1090
T + P T G TL++ P + + AP E + +
Sbjct: 597 PTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 656
Query: 1091 LPAQDKAIVFEIMEAGEPTGPILGAEALPGGL------RTLPQEPGKPQKDEV----LRY 1140
P K + PT P A P G P P KP E+ +
Sbjct: 657 APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKG 716
Query: 1141 PDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRWPEVSPEDTQSLS-- 1198
P + S + A + + P+ TPK P T PE P T +S
Sbjct: 717 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT---------PETPPPTTSEVSTP 767
Query: 1199 -LSEESPSKETSLDVSSKQLSPE-SLGTLQFGELNLGKEEMGHLMQAEDTSHHTAPMSVP 1256
++E + S D S+ +LS E + L+ G + TA
Sbjct: 768 TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTT 827
Query: 1257 EPHAATASPPTDGTTRYSAQTDITDDSLDRKSPASSFSHSTPSGNGKYLPGAITSPDEHI 1316
E T T + + +T T + ++ + T + P IT+
Sbjct: 828 ERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTT 887
Query: 1317 LTPDSSFSK----SPESLPGPALEDIAIKWEDKVPGLKDRTSE-QKKEPEPKDEVLQQKD 1371
L P + +K + E + P E+ A K +D+ K T + QK PK +K
Sbjct: 888 LAPKVTTTKKTITTTEIMNKP--EETA-KPKDRATNSKATTPKPQKPTKAPKKPTSTKKP 944
Query: 1372 KTLEHKEVVEPKDTAIYQK 1390
KT+ V +PK T +K
Sbjct: 945 KTM--PRVRKPKTTPTPRK 961
Score = 36.6 bits (83), Expect = 0.36
Identities = 75/323 (23%), Positives = 105/323 (32%), Gaps = 47/323 (14%)
Query: 295 TQKDLASGAVPTNLKPSKIKQRADS--KESLKATTKTAVSKLAKR------EEVVEEGAK 346
T + + P L P+ ++ + +E T K A K +E K
Sbjct: 542 TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK 601
Query: 347 EARSELAKELAKTEKKA------KESSEKPPEKPAKPERVKTESSE--ALKAEKRKLIKD 398
E KE A T K KE + P+KPA E T + E + +K
Sbjct: 602 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 661
Query: 399 KVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTK-PELK 457
K G K K+ K K+ KK A KE TK P
Sbjct: 662 K-GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 720
Query: 458 KISKPDLKPFTP-EVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPT 516
KP P TP E T K P K K + P+TPP V PT
Sbjct: 721 TSDKP--APTTPKETAPTTPKEPAPTTPK----------KPAPTTPETPPPTTSEVSTPT 768
Query: 517 ISGHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAI-QG 575
+ + SP++ T + L AE L + P E G P+T
Sbjct: 769 TTKEPTTIHKSPDESTPE----------LSAEPTPKALENSP-----KEPGVPTTKTPAA 813
Query: 576 TPPSVPGLGQEEHVMKEKELVPE 598
T P + +++ ++ PE
Sbjct: 814 TKPEMTTTAKDKTTERDLRTTPE 836
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 103 bits (258), Expect = 2e-21
Identities = 179/823 (21%), Positives = 266/823 (32%), Gaps = 112/823 (13%)
Query: 1855 APLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEG 1914
AP S PTP E+ T P T + +E A+ P P + A
Sbjct: 281 APTSKVLAKPTPKAETTTKGPAL--TTPKEPTPTTPKEPASTT---PKEPTPTTIKSAPT 335
Query: 1915 EREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPT----PYPDERSFQYADI 1970
+E AP + + P+ T EP T P++ PT P P
Sbjct: 336 TPKEP----APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 391
Query: 1971 YEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDT 2030
E T PA T + P P + KE A T+ E ++P P
Sbjct: 392 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP---TTKEPAPTTPKEPAPTAPKK 448
Query: 2031 PTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVP-----PRAPILSKGPSPPLNGNILSCS 2085
P + PT P P P + EPS T P P AP +K P+P + +
Sbjct: 449 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS-APTT 507
Query: 2086 PDRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAH 2145
P SP+ + + + +K A P KE +P P P + P T
Sbjct: 508 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KEPAPTTPKEPAPTTTKKPAPTTPKE 566
Query: 2146 VSPPLDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALA 2205
+P P P P + L P P+ P+P P +
Sbjct: 567 PAPTTPKETAPTTPKKLTPTTP---EKLAPTTPEKPAPTTP------------EELAPTT 611
Query: 2206 PGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSP--GAPLLSNLPRPASPALSEGSSSEA 2263
P PT T +E T + ++ P+ P+P++P AP P P +P + ++ +
Sbjct: 612 PEEPTPTTPEEPAPTTPKAAAPNT-PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 670
Query: 2264 TTPVISSVAERFSPSLEA---------AEQESGELDPGMEPAAHSLWDLTPLSPAPPASL 2314
T P +P A E S D TP PAP
Sbjct: 671 TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 730
Query: 2315 DLALAPAPSLPGDMGDGILPCHL-ECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGPA 2373
+ PAP+ P G P L E + +KP+P ++ GPT T+ + P P
Sbjct: 731 E----PAPTTP----KGTAPTTLKEPAPTTPKKPAPKEL--APTTTKGPTSTTSDKPAPT 780
Query: 2374 PAKAENEEAAACPAWERGAWPEGAERSSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAG 2433
K E A P E A + + +PE P P ++ P
Sbjct: 781 TPK---ETAPTTP-------KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP----- 825
Query: 2434 PQGCATEPRPHRGELSPSFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCP 2493
T E +P P P ++++ + G TT P
Sbjct: 826 -----TTIHKSPDESTPELSAEPTPKALENSP---------------KEPGVPTTKTPAA 865
Query: 2494 VTDETPPTSASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHH 2553
E T+A D + + P T P +T E A +++ + V+ T
Sbjct: 866 TKPEM-TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTST-- 922
Query: 2554 PRPGHDPPPLPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKA 2613
D P + + P V ++E + + E K + R
Sbjct: 923 --TTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI--MNKPEETAKPKDRATNSKATTP 978
Query: 2614 KPASPARRLDLRGKRSPTPGKGPAD----RASRAPPRPRSTTS 2652
KP P + + PT K P R + P PR TS
Sbjct: 979 KPQKPT-----KAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS 1016
Score = 77.8 bits (190), Expect = 1e-13
Identities = 150/706 (21%), Positives = 228/706 (32%), Gaps = 107/706 (15%)
Query: 2001 STKEAAAGRNTSAE------KELSSPISPKSLQSDTPTFSYAALAGPTVPPRP------E 2048
S KE + TSA+ K L+ P + P + PT P P E
Sbjct: 265 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKE 324
Query: 2049 PGPS------MEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSP----------- 2091
P P+ P P AP K P+P +P +P
Sbjct: 325 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 384
Query: 2092 -----SPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHV 2146
+PKE + + E E +P P P P+ A
Sbjct: 385 KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 444
Query: 2147 SPPLDSHLGPARPSLDFPASAFGFSSLQPAP--PQLPSPAEPRSAPCGSL--AFSGDRAL 2202
+P + P P+ P ++ +P+P P+ P+P +SAP + A + ++
Sbjct: 445 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 504
Query: 2203 ALAPGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSP--GAPLLSNLPRPASPALSEGSS 2260
P P+ T TK P+ + P+ P+P++P AP P P +P ++
Sbjct: 505 PTTPKEPSPT-------TTKEPA--PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 555
Query: 2261 SEATTPVISSVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAP 2320
++ P +P E A +L P L TP PAP +L
Sbjct: 556 TKKPAPTTPKEPAPTTPK-ETAPTTPKKLTP---TTPEKLAPTTPEKPAPTTPEEL---- 607
Query: 2321 APSLPGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENE 2380
AP+ P E + E+P+P + A N P E +P P E
Sbjct: 608 APTTPE-----------EPTPTTPEEPAP--TTPKAAAPNTPKEPAPTTPKEPAPTTPKE 654
Query: 2381 EAAACPAWERGAWPEGAERSSRPDTLL--SPEQPVCPAGGSGGPPSSASPEVEAGPQGCA 2438
A P P+G + P TL +P P PA P ++ P +
Sbjct: 655 PAPTTPKETAPTTPKG----TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 710
Query: 2439 TEPRPHRGELSPSFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDET 2498
T P+ +P+ P P + + +T + P T P P T +
Sbjct: 711 TTPK----GTAPTTPKEPAPTTPKEPAPTTP-----------KGTAPTTLKEPAPTTPKK 755
Query: 2499 P------PTSASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTH 2552
P PT+ S+ SD P +E T + E P A T
Sbjct: 756 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK------EPAPTTPKKPAPTTPETP 809
Query: 2553 HPRPGHDPPPLPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGK 2612
P P +P PD + PE LS+E + L K G + P
Sbjct: 810 PPTTSEVSTPTTTKEPTTIHKSPD--ESTPE-LSAEP-TPKALENSPKEPGVPTTKTPAA 865
Query: 2613 AKPASPARRLDLRGKRSPTPGKGPADRASRAPPRPRSTTSQVTPAE 2658
KP D +R A + +TT + T ++
Sbjct: 866 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESK 911
Score = 77.0 bits (188), Expect = 2e-13
Identities = 175/823 (21%), Positives = 268/823 (32%), Gaps = 177/823 (21%)
Query: 1848 KDRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAE-LEGGPYSPLG 1906
K +P P P+ G + P + T +++ V + + A+ + P P
Sbjct: 168 KKKPTPKPPVVDEAGSGLDNGDFKVTTPDT-STTQHNKVSTSPKITTAKPINPRPSLPPN 226
Query: 1907 KDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQ 1966
D K + +++ ++K TT ++T+ ++ S
Sbjct: 227 SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV 286
Query: 1967 YADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSL 2026
A + T GPA T + P P + KE SA P +PK
Sbjct: 287 LAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA------PTTPKE- 339
Query: 2027 QSDTPTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSP 2086
PT + +A PT P P P + EP+ T P P AP +K P+P + +
Sbjct: 340 --PAPTTTKSA---PTTPKEPAPTTTKEPAPTTPKEP--APTTTKEPAPTTTKSAPTTPK 392
Query: 2087 DRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQS-PSPPHPIPMGSPTLWPETEAH 2145
+ +PK K A P++ A + P P P P + A
Sbjct: 393 EPAPTTPK-----------------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 435
Query: 2146 VSPPLDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALA 2205
+P + P +P+ P P+ P+P P+
Sbjct: 436 TTPKEPAPTAPKKPA--------------PTTPKEPAPTTPKE----------------- 464
Query: 2206 PGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSP-GAPLLSNLPRPASPALSEGSSSEAT 2264
P P T TK PS + P+ P+P++ AP + P P + + S T
Sbjct: 465 PAPTT----------TKEPS--PTTPKEPAPTTTKSAPTTTKEPAPTT------TKSAPT 506
Query: 2265 TPVISSVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAPAPSL 2324
TP S P+ + EPA TP PAP + PAP+
Sbjct: 507 TPKEPSPTTTKEPAPTTPK----------EPAP-----TTPKKPAPTTPKE----PAPTT 547
Query: 2325 PGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAA 2384
P E + T+KP+P P E A P ET+P P + A
Sbjct: 548 PK-----------EPAPTTTKKPAP-TTPKEP-APTTPKETAPTTPKKLTPTTPEKLAPT 594
Query: 2385 CPAWERGAWPEG-AERSSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRP 2443
P PE A + T +PE+P P +A+P P T P+
Sbjct: 595 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT------PKAAAPNTPKEP--APTTPK- 645
Query: 2444 HRGELSPSFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETP-PTS 2502
E +P+ P P + + P T G P T + P PT+
Sbjct: 646 ---EPAPTTPKEPAPTTPKET-------------------APTTPKGTAPTTLKEPAPTT 683
Query: 2503 ASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRP----GH 2558
+ P T+E S T + + G K + P P G
Sbjct: 684 PKKPAPKEL---APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 740
Query: 2559 DPPPLPQPDPR-PSPPRP-DVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPA 2616
P L +P P P P P ++ +G +S + + P + P
Sbjct: 741 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS------------DKPAPTTPKETAPT 788
Query: 2617 SPARRLDLRGKRSPTPGKGPADRASRAPPRPRSTTSQVTPAEE 2659
+P + +PT K PA PP S S T +E
Sbjct: 789 TPK-------EPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE 824
Score = 72.0 bits (175), Expect = 8e-12
Identities = 100/437 (22%), Positives = 138/437 (31%), Gaps = 62/437 (14%)
Query: 1719 PHYTEERESTFLDEGPDDEQEVPLREHATRSPWASDFKDFQESSPQKGLEVERWLAESPV 1778
P T+E T P +E T+ P + K+ ++P+K + P
Sbjct: 490 PTTTKEPAPTTTKSAPTTPKEPS--PTTTKEPAPTTPKEPAPTTPKKPAPTT---PKEPA 544
Query: 1779 GLPPEEEDKLTRSPFEIISPPASPPEMVGQRVPSAPGQESPIPDPKLMPHM--KNEPTTP 1836
P+E T +P P + P+ P + +P KL P K PTTP
Sbjct: 545 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 604
Query: 1837 SWLADIPPWVPKDRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAE 1896
LA P + P P P PAP P A + P E
Sbjct: 605 EELAPTTP----EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 660
Query: 1897 LEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATT---EPEQTEPEQ 1953
E P +P G +E P K + P +K +T +P T P+
Sbjct: 661 KETAPTTPKG-----TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 715
Query: 1954 REPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSA 2013
PT P E + P P P G P L + A A
Sbjct: 716 TAPTT-PKEPA----------------PTTPKEPAPTTPKGTAPTTLK-EPAPTTPKKPA 757
Query: 2014 EKELSSPIS--PKSLQSDTPTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSK 2071
KEL+ + P S SD P + PT P P P +P+ T P PP
Sbjct: 758 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 817
Query: 2072 GPSPPLNGNILSCSPDRRSP-------------SPKESG----------RSHWDDSTSDS 2108
P+ + SPD +P SPKE G + + D
Sbjct: 818 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDK 877
Query: 2109 ELEKGAREQPEKEAQSP 2125
E+ R PE +P
Sbjct: 878 TTERDLRTTPETTTAAP 894
Score = 63.9 bits (154), Expect = 2e-09
Identities = 195/904 (21%), Positives = 290/904 (32%), Gaps = 114/904 (12%)
Query: 766 PRFHTSTYDLPGPEGAGPFEASQPADSAVPATSGKVYGTPETELTYPTNIVAAPLAEEEH 825
P S+ P P GA S S P K E+E + V+
Sbjct: 69 PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSS 128
Query: 826 VSSATSITECDKLSSFATSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEATQG 885
SS++S + K+ S S A + L + K + T P EA G
Sbjct: 129 SSSSSSSSTIRKIKSSKNSAANRELQKKLKV----KDNKKNRTKKKPTPKPPVVDEAGSG 184
Query: 886 LDYVPSAGTISPTSSLEEDKGFKSP---------PCEDFSVTGESEKRGEIIGKGLSGER 936
LD T TS+ + +K SP P ++ K + ++ E
Sbjct: 185 LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLT---VNKET 241
Query: 937 AVEEEEEETANVEMS----EKLCSQYGTP-VFSAPGHALHPGEPALGE----AEERCLSP 987
VE +E T N + S EK S T + L P L + AE P
Sbjct: 242 TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP 301
Query: 988 DDSTVKMASP-----PPSGPP---------SATHTPFHQSPVEEKSEPQDFQEADSWGDT 1033
+T K +P P S P SA TP +P KS P +E
Sbjct: 302 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTK 361
Query: 1034 KRTPGVGKEDAAEETVKPGP-EEGTLEKEEKVPPPRSPQAQEAPVNIDEGLTGCTIQLLP 1092
+ P KE A T +P P + K P P +P+ + AP E P
Sbjct: 362 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPTTPKE----------P 410
Query: 1093 AQDKAIVFEIMEAGEPTGPILGAEALPGGLRTLPQEPGKPQKDEVLRYPDRSLSPEDAES 1152
A PT P E P T P+EP K+ P + E A +
Sbjct: 411 A--------------PTTP---KEPTP----TTPKEPAPTTKE-----PAPTTPKEPAPT 444
Query: 1153 LSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRWPEVSPEDTQSLSLSEESPSKETSLDV 1212
P+ TPK P T + E +P T+S + + P+ T+
Sbjct: 445 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 504
Query: 1213 SSKQLSPESLGTLQFGELNLGKEEMGHLMQAEDTSHHTAPMSVPEPHAATASPPTDGTTR 1272
+ P T + KE A T AP + EP T P TT+
Sbjct: 505 PTTPKEPSPTTTKEPAP-TTPKE------PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 557
Query: 1273 YSAQTDITD--DSLDRKSPASSFSHSTPSGNGKYLP-----GAITSPDEHI-LTPDSSFS 1324
A T + + +++ ++ TP+ K P A T+P+E TP+
Sbjct: 558 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 617
Query: 1325 KSPESLPGPALEDIAIKWEDKVPG---LKDRTSEQKKEPEP--KDEVLQQKDKTLEHKEV 1379
+PE P P A K P K+ KEP P E K +
Sbjct: 618 TTPEE-PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL 676
Query: 1380 VEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTA--LEQKDKALEPKD--KD 1435
EP T +K + K+ K K TA ++ PK+
Sbjct: 677 KEPAPTT-PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 735
Query: 1436 LEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEK 1495
+ K+ P K ++ K DK + E P+E
Sbjct: 736 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK--ETAPTTPKEP 793
Query: 1496 DKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQK--DKVSEKKDQALEQ 1553
+K + P T +E+ T K P H++ ++ + +E +ALE
Sbjct: 794 APTTPKKPAPTTPETPPPTTSEV---STPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 850
Query: 1554 KYWALG----QKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEE 1609
G + A + + ++ T+ E T PKM +E + K E
Sbjct: 851 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES 910
Query: 1610 KLEA 1613
K+ A
Sbjct: 911 KITA 914
Score = 61.2 bits (147), Expect = 1e-08
Identities = 197/981 (20%), Positives = 329/981 (33%), Gaps = 131/981 (13%)
Query: 317 ADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKP-- 374
++++ES +++ ++ S ++ + + A A EL K+L + K + +KP KP
Sbjct: 120 SENQESSSSSSSSSSSSTIRKIKSSKNSA--ANRELQKKLKVKDNKKNRTKKKPTPKPPV 177
Query: 375 ---------------AKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKE 419
P+ T+ ++ + K K + L +E
Sbjct: 178 VDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTV 237
Query: 420 KKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAK 479
KE E KE K+ D K++ ++K S DL P + + K KA+
Sbjct: 238 NKETTVETKETTTT--NKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAE 295
Query: 480 VPGRVKIDRSRAIRGEKE-LSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEM 538
+ A+ KE + P+ P + P PT P T
Sbjct: 296 T-----TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT 350
Query: 539 KREERALLAEQRDTGLGDK-PFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVP 597
+E A + K P P T E P +T T P P K+ P
Sbjct: 351 TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA------PTTPKKPAP 404
Query: 598 EVPEEQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIEKAE 657
P+E T +E K+ + P T +E + K+
Sbjct: 405 TTPKE---------PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA----- 450
Query: 658 LEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFGGRELGLQGKAPEKETSL 717
P+ +E T + +EP TP+ + K P T+
Sbjct: 451 --------PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT- 501
Query: 718 FLSSLTTPAGATEHVSYIQDETIPGYSETEQTISDEEIHDEPEERPAPPRFHTSTYDLPG 777
S+ TTP + + T P E T + P+E PAP +T P
Sbjct: 502 -KSAPTTPKEPSPTTTKEPAPTTP--KEPAPTTPKKPAPTTPKE-PAP-----TTPKEPA 552
Query: 778 PEGAGPFEASQPADSAVPATSGKVYGTPETELTYPTNIVAAPLAEEEHVSSATSITECDK 837
P + P + A P T + T +LT T AP E+ + T ++
Sbjct: 553 PTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLTPTTPEKLAPTTPEK-----PAPTTPEE 606
Query: 838 LSSFATSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEATQGLDYVPSAGTISP 897
L+ T + AP T + + + + P T + +P
Sbjct: 607 LAP-TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 665
Query: 898 TSSLEEDKGFKSPPCEDFSVTGESEKRGEIIGKGLSGERAVEEEEEETANVEMSEKLCSQ 957
T+ KG ++ + T + ++ +E T E + C +
Sbjct: 666 TT----PKGTAPTTLKEPAPT--------------TPKKPAPKELAPTTTKEPTSTTCDK 707
Query: 958 YG--TPVFSAPGHALHPGEPALGEAEERCLSPDDSTVKMASPPPSGPPSATHTPFHQSPV 1015
TP +AP P EPA +E P +T K +P P+ T TP + P
Sbjct: 708 PAPTTPKGTAP---TTPKEPAPTTPKE----PAPTTPKGTAPTTLKEPAPT-TP--KKPA 757
Query: 1016 EEKSEPQDFQEADSWGDTKRTPGVGKEDAAEETVKPGPEEGTLEKEEKVPPPRSPQAQEA 1075
++ P + S K P KE A +P P K P P +P E
Sbjct: 758 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP------TTPKKPAPTTP---ET 808
Query: 1076 PVNIDEGLTGCTIQLLPAQDKAIVFEIMEAGEPTGPILGAEALPGGLRTLPQEPGKP-QK 1134
P ++ T P I ++ + + P L AE P L P+EPG P K
Sbjct: 809 PPPTTSEVSTPTTTKEPT-------TIHKSPDESTPELSAEPTPKALENSPKEPGVPTTK 861
Query: 1135 DEVLRYPDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRWPEVSPEDT 1194
P+ + + +D + L +P+T P T + + + + + T
Sbjct: 862 TPAATKPEMTTTAKDKTTERDLRT-TPETTTAAPKMTKETATTTEKTTESKITATTTQVT 920
Query: 1195 QSLSLSEESPSKETSLDVSSKQLSPE---SLGTLQFGELNLGKEEMGHLMQAEDTSHHTA 1251
S + + +P K T+L ++ L+P+ + T+ E+ EE S T
Sbjct: 921 -STTTQDTTPFKITTLKTTT--LAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT- 976
Query: 1252 PMSVPEPHAATASPPTDGTTR 1272
P+P T +P +T+
Sbjct: 977 ---TPKPQKPTKAPKKPTSTK 994
Score = 61.2 bits (147), Expect = 1e-08
Identities = 139/661 (21%), Positives = 203/661 (30%), Gaps = 128/661 (19%)
Query: 2058 TPPAVPPRAPILSKGPSPPLNGNILSCS---PDRRSPSPKESGRSHWDDSTSDSELEKGA 2114
T P + PI + PP + S + KE+ ++ ST E A
Sbjct: 207 TSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSA 266
Query: 2115 REQP--EKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFPASAFGFSS 2172
+E EK + P + PT ET P L + P + PAS
Sbjct: 267 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTK-GPALTTPKEPTPTTPKEPAST----- 320
Query: 2173 LQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQ 2232
P+ P+P +SAP P P T K P+ ++
Sbjct: 321 ----TPKEPTPTTIKSAPT-------------TPKEPAPTTTKSAPTTPKEPAPTTTKEP 363
Query: 2233 LPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFSPSLEAAEQESGELDPG 2292
P+ AP + P P + + S TTP + P+ +
Sbjct: 364 APTTPKEPAPTTTKEPAPTT------TKSAPTTPKEPAPTTPKKPAPTTPK--------- 408
Query: 2293 MEPAAHSLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLECSEAATEKPSPFQV 2352
EPA + + TP +P PA PAP+ P E + A +KP+P
Sbjct: 409 -EPAPTTPKEPTPTTPKEPAPT--TKEPAPTTPK-----------EPAPTAPKKPAP-TT 453
Query: 2353 PSEDCAANGPTETSPNPPGPAPAKAENEEAAACPAWERGAWPEGAERSSRPDTLLSPEQP 2412
P E P T+P P P K + PA S P T P
Sbjct: 454 PKE------PAPTTPKEPAPTTTKEPSPTTPKEPA--------PTTTKSAPTTTKEP--- 496
Query: 2413 VCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPPLPPSIDDRDLSTEEVR 2472
P P + P + T P+ E +P+ P P + + +T
Sbjct: 497 -APTTTKSAPTTPKEPSPTTTKEPAPTTPK----EPAPTTPKKPAPTTPKEPAPTTP--- 548
Query: 2473 LVGRGGRRRVGGPGTTGGPCPVTDETP-----------------PTSASDSGSSQSDSDV 2515
+ P TT P P T + P PT+ + +
Sbjct: 549 --------KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 600
Query: 2516 PPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRP 2575
P EE T E + + KA + P P P P P+P P
Sbjct: 601 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 660
Query: 2576 -DVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASPARRLDLR-GKRSPTPG 2633
+ P+G + + KE + AP + P + K +PT
Sbjct: 661 KETAPTTPKGTAPTT-------LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 713
Query: 2634 KG-----PADRASRAPPRPRSTTSQVT-PAEEKD-----GHSPMSKGLVNGLKAGPMALS 2682
KG P + A P P TT + T P K+ P K L GP + +
Sbjct: 714 KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTT 773
Query: 2683 S 2683
S
Sbjct: 774 S 774
Score = 53.5 bits (127), Expect = 3e-06
Identities = 209/1063 (19%), Positives = 339/1063 (31%), Gaps = 161/1063 (15%)
Query: 366 SSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEK----- 420
SS+K P + +K+ + + K +K K + + + E+ S E ++
Sbjct: 74 SSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSS 133
Query: 421 -----KEIKKERKELKKDEGRKEEK-KDAKKEEKRKDTKPELKKISKP-------DLKPF 467
++IK + E +K+ K KD KK +K P+ + + D K
Sbjct: 134 SSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVT 193
Query: 468 TPEVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSS 527
TP+ T + K+ S I K ++ P PP T +++ ++E + +
Sbjct: 194 TPDTSTTQHN-------KVSTSPKITTAKPINPRPSLPP-NSDTSKETSLTVNKETTVET 245
Query: 528 PEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEE 587
E T + ++ + + ++T +K D A P S + P +
Sbjct: 246 KETTTTN-KQTSTDGKEKTTSAKETQSIEKTSAKDLA---PTSKVLAKPTPKAETTTKGP 301
Query: 588 HVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPE 647
+ KE P P+E S E T + E P T++ + E
Sbjct: 302 ALTTPKEPTPTTPKEPAST-------TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE 354
Query: 648 VKEDVIEKAELEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFGGRELGLQ 707
++ +E P+ +E T + +EP TP+ +E
Sbjct: 355 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA-PTTPKEPAPTTPKKPAPTTPKE---- 409
Query: 708 GKAPEKETSLFLSSLTTPAGATEHVSYIQDETIPGYSETEQTISDEEIHDEPEERPAPPR 767
AP TTP T E P E T E P+ +PAP
Sbjct: 410 -PAP-----------TTPKEPTPTTP---KEPAPTTKEPAPTTPKEPAPTAPK-KPAPTT 453
Query: 768 FHTSTYDLPGPEGAGPFEASQPADSAVPATSGKVYGTPETELTYPTNIVAAPLAEEEHVS 827
P+ P +PA P T+ + T E PT +AP +E
Sbjct: 454 ----------PKEPAPTTPKEPA----PTTTKEPSPTTPKEPA-PTTTKSAPTTTKEPAP 498
Query: 828 SAT-SITECDKLSSFATSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEATQGL 886
+ T S K S T+ + AP T + + + + P T
Sbjct: 499 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT--- 555
Query: 887 DYVPSAGTISPTSSLEEDKGFKSPPCEDFSVTGESEKRGEIIGKGLSGERAVEEEEEETA 946
T P + ++ +P +ETA
Sbjct: 556 -------TKKPAPTTPKEPAPTTP--------------------------------KETA 576
Query: 947 NVEMSEKLCSQYGTPVFSAPGHALHPGEPALGEAEERCLSPDDSTVKMASPPPSGPPSAT 1006
+KL TP AP P +PA EE L+P P P+ P
Sbjct: 577 PTT-PKKLTPT--TPEKLAP---TTPEKPAPTTPEE--LAPTTPE----EPTPTTPEEPA 624
Query: 1007 HTPFHQSPVEEKSEPQDFQEADSWGDTKRTPGVGKEDAAEETVKPGPEEGTLEKEEKVPP 1066
T + EP + T + P T G TL++ P
Sbjct: 625 PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 684
Query: 1067 PRSPQAQEAPVNIDEGLTGCTIQLLPAQDKAIVFEIMEAGEPTGPILGAEALPGGL---- 1122
+ + AP E + + P K + PT P A P G
Sbjct: 685 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 744
Query: 1123 --RTLPQEPGKPQKDEV----LRYPDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGL 1176
P P KP E+ + P + S + A + + P+ TPK P
Sbjct: 745 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 804
Query: 1177 TEQYLHKDRWPEVSPEDTQSLS---LSEESPSKETSLDVSSKQLSPE-SLGTLQFGELNL 1232
T PE P T +S ++E + S D S+ +LS E + L+
Sbjct: 805 T---------PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 855
Query: 1233 GKEEMGHLMQAEDTSHHTAPMSVPEPHAATASPPTDGTTRYSAQTDITDDSLDRKSPASS 1292
G + TA E T T + + +T T + ++
Sbjct: 856 GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITAT 915
Query: 1293 FSHSTPSGNGKYLPGAITSPDEHILTPDSSFSK----SPESLPGPALEDIAIKWEDKVPG 1348
+ T + P IT+ L P + +K + E + P E+ A K +D+
Sbjct: 916 TTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP--EETA-KPKDRATN 972
Query: 1349 LKDRTSE-QKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQK 1390
K T + QK PK +K KT+ V +PK T +K
Sbjct: 973 SKATTPKPQKPTKAPKKPTSTKKPKTM--PRVRKPKTTPTPRK 1013
Score = 36.6 bits (83), Expect = 0.36
Identities = 75/323 (23%), Positives = 105/323 (32%), Gaps = 47/323 (14%)
Query: 295 TQKDLASGAVPTNLKPSKIKQRADS--KESLKATTKTAVSKLAKR------EEVVEEGAK 346
T + + P L P+ ++ + +E T K A K +E K
Sbjct: 594 TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK 653
Query: 347 EARSELAKELAKTEKKA------KESSEKPPEKPAKPERVKTESSE--ALKAEKRKLIKD 398
E KE A T K KE + P+KPA E T + E + +K
Sbjct: 654 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 713
Query: 399 KVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTK-PELK 457
K G K K+ K K+ KK A KE TK P
Sbjct: 714 K-GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 772
Query: 458 KISKPDLKPFTP-EVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPT 516
KP P TP E T K P K K + P+TPP V PT
Sbjct: 773 TSDKP--APTTPKETAPTTPKEPAPTTPK----------KPAPTTPETPPPTTSEVSTPT 820
Query: 517 ISGHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAI-QG 575
+ + SP++ T + L AE L + P E G P+T
Sbjct: 821 TTKEPTTIHKSPDESTPE----------LSAEPTPKALENSP-----KEPGVPTTKTPAA 865
Query: 576 TPPSVPGLGQEEHVMKEKELVPE 598
T P + +++ ++ PE
Sbjct: 866 TKPEMTTTAKDKTTERDLRTTPE 888
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 103 bits (258), Expect = 2e-21
Identities = 179/823 (21%), Positives = 266/823 (32%), Gaps = 112/823 (13%)
Query: 1855 APLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEG 1914
AP S PTP E+ T P T + +E A+ P P + A
Sbjct: 322 APTSKVLAKPTPKAETTTKGPAL--TTPKEPTPTTPKEPASTT---PKEPTPTTIKSAPT 376
Query: 1915 EREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPT----PYPDERSFQYADI 1970
+E AP + + P+ T EP T P++ PT P P
Sbjct: 377 TPKEP----APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 432
Query: 1971 YEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDT 2030
E T PA T + P P + KE A T+ E ++P P
Sbjct: 433 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAP---TTKEPAPTTPKEPAPTAPKK 489
Query: 2031 PTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVP-----PRAPILSKGPSPPLNGNILSCS 2085
P + PT P P P + EPS T P P AP +K P+P + +
Sbjct: 490 PAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS-APTT 548
Query: 2086 PDRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAH 2145
P SP+ + + + +K A P KE +P P P + P T
Sbjct: 549 PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KEPAPTTPKEPAPTTTKKPAPTTPKE 607
Query: 2146 VSPPLDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALA 2205
+P P P P + L P P+ P+P P +
Sbjct: 608 PAPTTPKETAPTTPKKLTPTTP---EKLAPTTPEKPAPTTP------------EELAPTT 652
Query: 2206 PGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSP--GAPLLSNLPRPASPALSEGSSSEA 2263
P PT T +E T + ++ P+ P+P++P AP P P +P + ++ +
Sbjct: 653 PEEPTPTTPEEPAPTTPKAAAPNT-PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 711
Query: 2264 TTPVISSVAERFSPSLEA---------AEQESGELDPGMEPAAHSLWDLTPLSPAPPASL 2314
T P +P A E S D TP PAP
Sbjct: 712 TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK 771
Query: 2315 DLALAPAPSLPGDMGDGILPCHL-ECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGPA 2373
+ PAP+ P G P L E + +KP+P ++ GPT T+ + P P
Sbjct: 772 E----PAPTTP----KGTAPTTLKEPAPTTPKKPAPKEL--APTTTKGPTSTTSDKPAPT 821
Query: 2374 PAKAENEEAAACPAWERGAWPEGAERSSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAG 2433
K E A P E A + + +PE P P ++ P
Sbjct: 822 TPK---ETAPTTP-------KEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP----- 866
Query: 2434 PQGCATEPRPHRGELSPSFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCP 2493
T E +P P P ++++ + G TT P
Sbjct: 867 -----TTIHKSPDESTPELSAEPTPKALENSP---------------KEPGVPTTKTPAA 906
Query: 2494 VTDETPPTSASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHH 2553
E T+A D + + P T P +T E A +++ + V+ T
Sbjct: 907 TKPEM-TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTST-- 963
Query: 2554 PRPGHDPPPLPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKA 2613
D P + + P V ++E + + E K + R
Sbjct: 964 --TTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI--MNKPEETAKPKDRATNSKATTP 1019
Query: 2614 KPASPARRLDLRGKRSPTPGKGPAD----RASRAPPRPRSTTS 2652
KP P + + PT K P R + P PR TS
Sbjct: 1020 KPQKPT-----KAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS 1057
Score = 77.8 bits (190), Expect = 1e-13
Identities = 150/706 (21%), Positives = 228/706 (32%), Gaps = 107/706 (15%)
Query: 2001 STKEAAAGRNTSAE------KELSSPISPKSLQSDTPTFSYAALAGPTVPPRP------E 2048
S KE + TSA+ K L+ P + P + PT P P E
Sbjct: 306 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKE 365
Query: 2049 PGPS------MEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSP----------- 2091
P P+ P P AP K P+P +P +P
Sbjct: 366 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 425
Query: 2092 -----SPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHV 2146
+PKE + + E E +P P P P+ A
Sbjct: 426 KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 485
Query: 2147 SPPLDSHLGPARPSLDFPASAFGFSSLQPAP--PQLPSPAEPRSAPCGSL--AFSGDRAL 2202
+P + P P+ P ++ +P+P P+ P+P +SAP + A + ++
Sbjct: 486 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 545
Query: 2203 ALAPGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSP--GAPLLSNLPRPASPALSEGSS 2260
P P+ T TK P+ + P+ P+P++P AP P P +P ++
Sbjct: 546 PTTPKEPSPT-------TTKEPA--PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 596
Query: 2261 SEATTPVISSVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAP 2320
++ P +P E A +L P L TP PAP +L
Sbjct: 597 TKKPAPTTPKEPAPTTPK-ETAPTTPKKLTP---TTPEKLAPTTPEKPAPTTPEEL---- 648
Query: 2321 APSLPGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENE 2380
AP+ P E + E+P+P + A N P E +P P E
Sbjct: 649 APTTPE-----------EPTPTTPEEPAP--TTPKAAAPNTPKEPAPTTPKEPAPTTPKE 695
Query: 2381 EAAACPAWERGAWPEGAERSSRPDTLL--SPEQPVCPAGGSGGPPSSASPEVEAGPQGCA 2438
A P P+G + P TL +P P PA P ++ P +
Sbjct: 696 PAPTTPKETAPTTPKG----TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 751
Query: 2439 TEPRPHRGELSPSFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDET 2498
T P+ +P+ P P + + +T + P T P P T +
Sbjct: 752 TTPK----GTAPTTPKEPAPTTPKEPAPTTP-----------KGTAPTTLKEPAPTTPKK 796
Query: 2499 P------PTSASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTH 2552
P PT+ S+ SD P +E T + E P A T
Sbjct: 797 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK------EPAPTTPKKPAPTTPETP 850
Query: 2553 HPRPGHDPPPLPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGK 2612
P P +P PD + PE LS+E + L K G + P
Sbjct: 851 PPTTSEVSTPTTTKEPTTIHKSPD--ESTPE-LSAEP-TPKALENSPKEPGVPTTKTPAA 906
Query: 2613 AKPASPARRLDLRGKRSPTPGKGPADRASRAPPRPRSTTSQVTPAE 2658
KP D +R A + +TT + T ++
Sbjct: 907 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESK 952
Score = 77.0 bits (188), Expect = 2e-13
Identities = 175/823 (21%), Positives = 268/823 (32%), Gaps = 177/823 (21%)
Query: 1848 KDRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAE-LEGGPYSPLG 1906
K +P P P+ G + P + T +++ V + + A+ + P P
Sbjct: 209 KKKPTPKPPVVDEAGSGLDNGDFKVTTPDT-STTQHNKVSTSPKITTAKPINPRPSLPPN 267
Query: 1907 KDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQ 1966
D K + +++ ++K TT ++T+ ++ S
Sbjct: 268 SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV 327
Query: 1967 YADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSL 2026
A + T GPA T + P P + KE SA P +PK
Sbjct: 328 LAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA------PTTPKE- 380
Query: 2027 QSDTPTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSP 2086
PT + +A PT P P P + EP+ T P P AP +K P+P + +
Sbjct: 381 --PAPTTTKSA---PTTPKEPAPTTTKEPAPTTPKEP--APTTTKEPAPTTTKSAPTTPK 433
Query: 2087 DRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQS-PSPPHPIPMGSPTLWPETEAH 2145
+ +PK K A P++ A + P P P P + A
Sbjct: 434 EPAPTTPK-----------------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 476
Query: 2146 VSPPLDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALA 2205
+P + P +P+ P P+ P+P P+
Sbjct: 477 TTPKEPAPTAPKKPA--------------PTTPKEPAPTTPKE----------------- 505
Query: 2206 PGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSP-GAPLLSNLPRPASPALSEGSSSEAT 2264
P P T TK PS + P+ P+P++ AP + P P + + S T
Sbjct: 506 PAPTT----------TKEPS--PTTPKEPAPTTTKSAPTTTKEPAPTT------TKSAPT 547
Query: 2265 TPVISSVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAPAPSL 2324
TP S P+ + EPA TP PAP + PAP+
Sbjct: 548 TPKEPSPTTTKEPAPTTPK----------EPAP-----TTPKKPAPTTPKE----PAPTT 588
Query: 2325 PGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAA 2384
P E + T+KP+P P E A P ET+P P + A
Sbjct: 589 PK-----------EPAPTTTKKPAP-TTPKEP-APTTPKETAPTTPKKLTPTTPEKLAPT 635
Query: 2385 CPAWERGAWPEG-AERSSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRP 2443
P PE A + T +PE+P P +A+P P T P+
Sbjct: 636 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTT------PKAAAPNTPKEP--APTTPK- 686
Query: 2444 HRGELSPSFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETP-PTS 2502
E +P+ P P + + P T G P T + P PT+
Sbjct: 687 ---EPAPTTPKEPAPTTPKET-------------------APTTPKGTAPTTLKEPAPTT 724
Query: 2503 ASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRP----GH 2558
+ P T+E S T + + G K + P P G
Sbjct: 725 PKKPAPKEL---APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGT 781
Query: 2559 DPPPLPQPDPR-PSPPRP-DVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPA 2616
P L +P P P P P ++ +G +S + + P + P
Sbjct: 782 APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS------------DKPAPTTPKETAPT 829
Query: 2617 SPARRLDLRGKRSPTPGKGPADRASRAPPRPRSTTSQVTPAEE 2659
+P + +PT K PA PP S S T +E
Sbjct: 830 TPK-------EPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE 865
Score = 72.0 bits (175), Expect = 8e-12
Identities = 100/437 (22%), Positives = 138/437 (31%), Gaps = 62/437 (14%)
Query: 1719 PHYTEERESTFLDEGPDDEQEVPLREHATRSPWASDFKDFQESSPQKGLEVERWLAESPV 1778
P T+E T P +E T+ P + K+ ++P+K + P
Sbjct: 531 PTTTKEPAPTTTKSAPTTPKEPS--PTTTKEPAPTTPKEPAPTTPKKPAPTT---PKEPA 585
Query: 1779 GLPPEEEDKLTRSPFEIISPPASPPEMVGQRVPSAPGQESPIPDPKLMPHM--KNEPTTP 1836
P+E T +P P + P+ P + +P KL P K PTTP
Sbjct: 586 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 645
Query: 1837 SWLADIPPWVPKDRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAE 1896
LA P + P P P PAP P A + P E
Sbjct: 646 EELAPTTP----EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 701
Query: 1897 LEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATT---EPEQTEPEQ 1953
E P +P G +E P K + P +K +T +P T P+
Sbjct: 702 KETAPTTPKG-----TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 756
Query: 1954 REPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSA 2013
PT P E + P P P G P L + A A
Sbjct: 757 TAPTT-PKEPA----------------PTTPKEPAPTTPKGTAPTTLK-EPAPTTPKKPA 798
Query: 2014 EKELSSPIS--PKSLQSDTPTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSK 2071
KEL+ + P S SD P + PT P P P +P+ T P PP
Sbjct: 799 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 858
Query: 2072 GPSPPLNGNILSCSPDRRSP-------------SPKESG----------RSHWDDSTSDS 2108
P+ + SPD +P SPKE G + + D
Sbjct: 859 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDK 918
Query: 2109 ELEKGAREQPEKEAQSP 2125
E+ R PE +P
Sbjct: 919 TTERDLRTTPETTTAAP 935
Score = 63.9 bits (154), Expect = 2e-09
Identities = 195/904 (21%), Positives = 290/904 (32%), Gaps = 114/904 (12%)
Query: 766 PRFHTSTYDLPGPEGAGPFEASQPADSAVPATSGKVYGTPETELTYPTNIVAAPLAEEEH 825
P S+ P P GA S S P K E+E + V+
Sbjct: 110 PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSS 169
Query: 826 VSSATSITECDKLSSFATSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEATQG 885
SS++S + K+ S S A + L + K + T P EA G
Sbjct: 170 SSSSSSSSTIRKIKSSKNSAANRELQKKLKV----KDNKKNRTKKKPTPKPPVVDEAGSG 225
Query: 886 LDYVPSAGTISPTSSLEEDKGFKSP---------PCEDFSVTGESEKRGEIIGKGLSGER 936
LD T TS+ + +K SP P ++ K + ++ E
Sbjct: 226 LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLT---VNKET 282
Query: 937 AVEEEEEETANVEMS----EKLCSQYGTP-VFSAPGHALHPGEPALGE----AEERCLSP 987
VE +E T N + S EK S T + L P L + AE P
Sbjct: 283 TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP 342
Query: 988 DDSTVKMASP-----PPSGPP---------SATHTPFHQSPVEEKSEPQDFQEADSWGDT 1033
+T K +P P S P SA TP +P KS P +E
Sbjct: 343 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTK 402
Query: 1034 KRTPGVGKEDAAEETVKPGP-EEGTLEKEEKVPPPRSPQAQEAPVNIDEGLTGCTIQLLP 1092
+ P KE A T +P P + K P P +P+ + AP E P
Sbjct: 403 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPTTPKE----------P 451
Query: 1093 AQDKAIVFEIMEAGEPTGPILGAEALPGGLRTLPQEPGKPQKDEVLRYPDRSLSPEDAES 1152
A PT P E P T P+EP K+ P + E A +
Sbjct: 452 A--------------PTTP---KEPTP----TTPKEPAPTTKE-----PAPTTPKEPAPT 485
Query: 1153 LSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRWPEVSPEDTQSLSLSEESPSKETSLDV 1212
P+ TPK P T + E +P T+S + + P+ T+
Sbjct: 486 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 545
Query: 1213 SSKQLSPESLGTLQFGELNLGKEEMGHLMQAEDTSHHTAPMSVPEPHAATASPPTDGTTR 1272
+ P T + KE A T AP + EP T P TT+
Sbjct: 546 PTTPKEPSPTTTKEPAP-TTPKE------PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 598
Query: 1273 YSAQTDITD--DSLDRKSPASSFSHSTPSGNGKYLP-----GAITSPDEHI-LTPDSSFS 1324
A T + + +++ ++ TP+ K P A T+P+E TP+
Sbjct: 599 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 658
Query: 1325 KSPESLPGPALEDIAIKWEDKVPG---LKDRTSEQKKEPEP--KDEVLQQKDKTLEHKEV 1379
+PE P P A K P K+ KEP P E K +
Sbjct: 659 TTPEE-PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTL 717
Query: 1380 VEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTA--LEQKDKALEPKD--KD 1435
EP T +K + K+ K K TA ++ PK+
Sbjct: 718 KEPAPTT-PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT 776
Query: 1436 LEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEK 1495
+ K+ P K ++ K DK + E P+E
Sbjct: 777 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK--ETAPTTPKEP 834
Query: 1496 DKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQK--DKVSEKKDQALEQ 1553
+K + P T +E+ T K P H++ ++ + +E +ALE
Sbjct: 835 APTTPKKPAPTTPETPPPTTSEV---STPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 891
Query: 1554 KYWALG----QKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEE 1609
G + A + + ++ T+ E T PKM +E + K E
Sbjct: 892 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTES 951
Query: 1610 KLEA 1613
K+ A
Sbjct: 952 KITA 955
Score = 61.2 bits (147), Expect = 1e-08
Identities = 197/981 (20%), Positives = 329/981 (33%), Gaps = 131/981 (13%)
Query: 317 ADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKP-- 374
++++ES +++ ++ S ++ + + A A EL K+L + K + +KP KP
Sbjct: 161 SENQESSSSSSSSSSSSTIRKIKSSKNSA--ANRELQKKLKVKDNKKNRTKKKPTPKPPV 218
Query: 375 ---------------AKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKE 419
P+ T+ ++ + K K + L +E
Sbjct: 219 VDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTV 278
Query: 420 KKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAK 479
KE E KE K+ D K++ ++K S DL P + + K KA+
Sbjct: 279 NKETTVETKETTTT--NKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAE 336
Query: 480 VPGRVKIDRSRAIRGEKE-LSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEM 538
+ A+ KE + P+ P + P PT P T
Sbjct: 337 T-----TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT 391
Query: 539 KREERALLAEQRDTGLGDK-PFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVP 597
+E A + K P P T E P +T T P P K+ P
Sbjct: 392 TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA------PTTPKKPAP 445
Query: 598 EVPEEQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIEKAE 657
P+E T +E K+ + P T +E + K+
Sbjct: 446 TTPKE---------PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA----- 491
Query: 658 LEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFGGRELGLQGKAPEKETSL 717
P+ +E T + +EP TP+ + K P T+
Sbjct: 492 --------PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT- 542
Query: 718 FLSSLTTPAGATEHVSYIQDETIPGYSETEQTISDEEIHDEPEERPAPPRFHTSTYDLPG 777
S+ TTP + + T P E T + P+E PAP +T P
Sbjct: 543 -KSAPTTPKEPSPTTTKEPAPTTP--KEPAPTTPKKPAPTTPKE-PAP-----TTPKEPA 593
Query: 778 PEGAGPFEASQPADSAVPATSGKVYGTPETELTYPTNIVAAPLAEEEHVSSATSITECDK 837
P + P + A P T + T +LT T AP E+ + T ++
Sbjct: 594 PTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLTPTTPEKLAPTTPEK-----PAPTTPEE 647
Query: 838 LSSFATSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEATQGLDYVPSAGTISP 897
L+ T + AP T + + + + P T + +P
Sbjct: 648 LAP-TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 706
Query: 898 TSSLEEDKGFKSPPCEDFSVTGESEKRGEIIGKGLSGERAVEEEEEETANVEMSEKLCSQ 957
T+ KG ++ + T + ++ +E T E + C +
Sbjct: 707 TT----PKGTAPTTLKEPAPT--------------TPKKPAPKELAPTTTKEPTSTTCDK 748
Query: 958 YG--TPVFSAPGHALHPGEPALGEAEERCLSPDDSTVKMASPPPSGPPSATHTPFHQSPV 1015
TP +AP P EPA +E P +T K +P P+ T TP + P
Sbjct: 749 PAPTTPKGTAP---TTPKEPAPTTPKE----PAPTTPKGTAPTTLKEPAPT-TP--KKPA 798
Query: 1016 EEKSEPQDFQEADSWGDTKRTPGVGKEDAAEETVKPGPEEGTLEKEEKVPPPRSPQAQEA 1075
++ P + S K P KE A +P P K P P +P E
Sbjct: 799 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP------TTPKKPAPTTP---ET 849
Query: 1076 PVNIDEGLTGCTIQLLPAQDKAIVFEIMEAGEPTGPILGAEALPGGLRTLPQEPGKP-QK 1134
P ++ T P I ++ + + P L AE P L P+EPG P K
Sbjct: 850 PPPTTSEVSTPTTTKEPT-------TIHKSPDESTPELSAEPTPKALENSPKEPGVPTTK 902
Query: 1135 DEVLRYPDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRWPEVSPEDT 1194
P+ + + +D + L +P+T P T + + + + + T
Sbjct: 903 TPAATKPEMTTTAKDKTTERDLRT-TPETTTAAPKMTKETATTTEKTTESKITATTTQVT 961
Query: 1195 QSLSLSEESPSKETSLDVSSKQLSPE---SLGTLQFGELNLGKEEMGHLMQAEDTSHHTA 1251
S + + +P K T+L ++ L+P+ + T+ E+ EE S T
Sbjct: 962 -STTTQDTTPFKITTLKTTT--LAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKAT- 1017
Query: 1252 PMSVPEPHAATASPPTDGTTR 1272
P+P T +P +T+
Sbjct: 1018 ---TPKPQKPTKAPKKPTSTK 1035
Score = 61.2 bits (147), Expect = 1e-08
Identities = 139/661 (21%), Positives = 203/661 (30%), Gaps = 128/661 (19%)
Query: 2058 TPPAVPPRAPILSKGPSPPLNGNILSCS---PDRRSPSPKESGRSHWDDSTSDSELEKGA 2114
T P + PI + PP + S + KE+ ++ ST E A
Sbjct: 248 TSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSA 307
Query: 2115 REQP--EKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFPASAFGFSS 2172
+E EK + P + PT ET P L + P + PAS
Sbjct: 308 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTK-GPALTTPKEPTPTTPKEPAST----- 361
Query: 2173 LQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQ 2232
P+ P+P +SAP P P T K P+ ++
Sbjct: 362 ----TPKEPTPTTIKSAPT-------------TPKEPAPTTTKSAPTTPKEPAPTTTKEP 404
Query: 2233 LPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFSPSLEAAEQESGELDPG 2292
P+ AP + P P + + S TTP + P+ +
Sbjct: 405 APTTPKEPAPTTTKEPAPTT------TKSAPTTPKEPAPTTPKKPAPTTPK--------- 449
Query: 2293 MEPAAHSLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLECSEAATEKPSPFQV 2352
EPA + + TP +P PA PAP+ P E + A +KP+P
Sbjct: 450 -EPAPTTPKEPTPTTPKEPAPT--TKEPAPTTPK-----------EPAPTAPKKPAP-TT 494
Query: 2353 PSEDCAANGPTETSPNPPGPAPAKAENEEAAACPAWERGAWPEGAERSSRPDTLLSPEQP 2412
P E P T+P P P K + PA S P T P
Sbjct: 495 PKE------PAPTTPKEPAPTTTKEPSPTTPKEPA--------PTTTKSAPTTTKEP--- 537
Query: 2413 VCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPPLPPSIDDRDLSTEEVR 2472
P P + P + T P+ E +P+ P P + + +T
Sbjct: 538 -APTTTKSAPTTPKEPSPTTTKEPAPTTPK----EPAPTTPKKPAPTTPKEPAPTTP--- 589
Query: 2473 LVGRGGRRRVGGPGTTGGPCPVTDETP-----------------PTSASDSGSSQSDSDV 2515
+ P TT P P T + P PT+ + +
Sbjct: 590 --------KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 641
Query: 2516 PPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRP 2575
P EE T E + + KA + P P P P P+P P
Sbjct: 642 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 701
Query: 2576 -DVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASPARRLDLR-GKRSPTPG 2633
+ P+G + + KE + AP + P + K +PT
Sbjct: 702 KETAPTTPKGTAPTT-------LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 754
Query: 2634 KG-----PADRASRAPPRPRSTTSQVT-PAEEKD-----GHSPMSKGLVNGLKAGPMALS 2682
KG P + A P P TT + T P K+ P K L GP + +
Sbjct: 755 KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTT 814
Query: 2683 S 2683
S
Sbjct: 815 S 815
Score = 53.5 bits (127), Expect = 3e-06
Identities = 209/1063 (19%), Positives = 339/1063 (31%), Gaps = 161/1063 (15%)
Query: 366 SSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEK----- 420
SS+K P + +K+ + + K +K K + + + E+ S E ++
Sbjct: 115 SSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSS 174
Query: 421 -----KEIKKERKELKKDEGRKEEK-KDAKKEEKRKDTKPELKKISKP-------DLKPF 467
++IK + E +K+ K KD KK +K P+ + + D K
Sbjct: 175 SSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVT 234
Query: 468 TPEVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSS 527
TP+ T + K+ S I K ++ P PP T +++ ++E + +
Sbjct: 235 TPDTSTTQHN-------KVSTSPKITTAKPINPRPSLPP-NSDTSKETSLTVNKETTVET 286
Query: 528 PEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEE 587
E T + ++ + + ++T +K D A P S + P +
Sbjct: 287 KETTTTN-KQTSTDGKEKTTSAKETQSIEKTSAKDLA---PTSKVLAKPTPKAETTTKGP 342
Query: 588 HVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPE 647
+ KE P P+E S E T + E P T++ + E
Sbjct: 343 ALTTPKEPTPTTPKEPAST-------TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKE 395
Query: 648 VKEDVIEKAELEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFGGRELGLQ 707
++ +E P+ +E T + +EP TP+ +E
Sbjct: 396 PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA-PTTPKEPAPTTPKKPAPTTPKE---- 450
Query: 708 GKAPEKETSLFLSSLTTPAGATEHVSYIQDETIPGYSETEQTISDEEIHDEPEERPAPPR 767
AP TTP T E P E T E P+ +PAP
Sbjct: 451 -PAP-----------TTPKEPTPTTP---KEPAPTTKEPAPTTPKEPAPTAPK-KPAPTT 494
Query: 768 FHTSTYDLPGPEGAGPFEASQPADSAVPATSGKVYGTPETELTYPTNIVAAPLAEEEHVS 827
P+ P +PA P T+ + T E PT +AP +E
Sbjct: 495 ----------PKEPAPTTPKEPA----PTTTKEPSPTTPKEPA-PTTTKSAPTTTKEPAP 539
Query: 828 SAT-SITECDKLSSFATSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEATQGL 886
+ T S K S T+ + AP T + + + + P T
Sbjct: 540 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT--- 596
Query: 887 DYVPSAGTISPTSSLEEDKGFKSPPCEDFSVTGESEKRGEIIGKGLSGERAVEEEEEETA 946
T P + ++ +P +ETA
Sbjct: 597 -------TKKPAPTTPKEPAPTTP--------------------------------KETA 617
Query: 947 NVEMSEKLCSQYGTPVFSAPGHALHPGEPALGEAEERCLSPDDSTVKMASPPPSGPPSAT 1006
+KL TP AP P +PA EE L+P P P+ P
Sbjct: 618 PTT-PKKLTPT--TPEKLAP---TTPEKPAPTTPEE--LAPTTPE----EPTPTTPEEPA 665
Query: 1007 HTPFHQSPVEEKSEPQDFQEADSWGDTKRTPGVGKEDAAEETVKPGPEEGTLEKEEKVPP 1066
T + EP + T + P T G TL++ P
Sbjct: 666 PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 725
Query: 1067 PRSPQAQEAPVNIDEGLTGCTIQLLPAQDKAIVFEIMEAGEPTGPILGAEALPGGL---- 1122
+ + AP E + + P K + PT P A P G
Sbjct: 726 KKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 785
Query: 1123 --RTLPQEPGKPQKDEV----LRYPDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGL 1176
P P KP E+ + P + S + A + + P+ TPK P
Sbjct: 786 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 845
Query: 1177 TEQYLHKDRWPEVSPEDTQSLS---LSEESPSKETSLDVSSKQLSPE-SLGTLQFGELNL 1232
T PE P T +S ++E + S D S+ +LS E + L+
Sbjct: 846 T---------PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 896
Query: 1233 GKEEMGHLMQAEDTSHHTAPMSVPEPHAATASPPTDGTTRYSAQTDITDDSLDRKSPASS 1292
G + TA E T T + + +T T + ++
Sbjct: 897 GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITAT 956
Query: 1293 FSHSTPSGNGKYLPGAITSPDEHILTPDSSFSK----SPESLPGPALEDIAIKWEDKVPG 1348
+ T + P IT+ L P + +K + E + P E+ A K +D+
Sbjct: 957 TTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKP--EETA-KPKDRATN 1013
Query: 1349 LKDRTSE-QKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQK 1390
K T + QK PK +K KT+ V +PK T +K
Sbjct: 1014 SKATTPKPQKPTKAPKKPTSTKKPKTM--PRVRKPKTTPTPRK 1054
Score = 36.6 bits (83), Expect = 0.36
Identities = 75/323 (23%), Positives = 105/323 (32%), Gaps = 47/323 (14%)
Query: 295 TQKDLASGAVPTNLKPSKIKQRADS--KESLKATTKTAVSKLAKR------EEVVEEGAK 346
T + + P L P+ ++ + +E T K A K +E K
Sbjct: 635 TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK 694
Query: 347 EARSELAKELAKTEKKA------KESSEKPPEKPAKPERVKTESSE--ALKAEKRKLIKD 398
E KE A T K KE + P+KPA E T + E + +K
Sbjct: 695 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 754
Query: 399 KVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTK-PELK 457
K G K K+ K K+ KK A KE TK P
Sbjct: 755 K-GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 813
Query: 458 KISKPDLKPFTP-EVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPT 516
KP P TP E T K P K K + P+TPP V PT
Sbjct: 814 TSDKP--APTTPKETAPTTPKEPAPTTPK----------KPAPTTPETPPPTTSEVSTPT 861
Query: 517 ISGHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAI-QG 575
+ + SP++ T + L AE L + P E G P+T
Sbjct: 862 TTKEPTTIHKSPDESTPE----------LSAEPTPKALENSP-----KEPGVPTTKTPAA 906
Query: 576 TPPSVPGLGQEEHVMKEKELVPE 598
T P + +++ ++ PE
Sbjct: 907 TKPEMTTTAKDKTTERDLRTTPE 929
>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
Length = 238
Score = 94.4 bits (233), Expect = 1e-18
Identities = 64/242 (26%), Positives = 122/242 (50%), Gaps = 43/242 (17%)
Query: 1436 LEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEK 1495
+ E+++ E++ K+ EE++ EQ++ EQ++K E ++K EQ++++ EQ+EK+ E++
Sbjct: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
Query: 1496 DKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKY 1555
+K +Q+ + E + + PEQK + EQ +++ EK+++ EQK
Sbjct: 61 EKMWEQEEKMWEQQ------------------RLPEQKEKMWEQDERLREKEERMREQKM 102
Query: 1556 WALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALL 1615
W Q ++ + E +TQE++ QE+K ++ + + + EK++ EEK+
Sbjct: 103 W----------QQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKM---- 148
Query: 1616 EKTKALGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTS 1675
QE + REQEEK ++ +Q +E E GE E +P T+
Sbjct: 149 -----------WEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTA 197
Query: 1676 PE 1677
E
Sbjct: 198 QE 199
Score = 89.0 bits (219), Expect = 6e-17
Identities = 51/184 (27%), Positives = 111/184 (60%), Gaps = 11/184 (5%)
Query: 1401 VKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQK 1460
++++++ E++ + E+++ EQ++K E ++K E+++K EQ++K+ E+++K EQ+
Sbjct: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
Query: 1461 DTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKD 1520
+ EQ++K E + + EQK+++ EQ E++ E++++ +QK+ V +M++
Sbjct: 61 EKMWEQEEKMWE-QQRLPEQKEKMWEQDERLREKEERMREQKM--------WQQVEKMRE 111
Query: 1521 RDLEQTDKAPEQKHQAQEQKDKV--SEKKDQALEQKYWALGQKDEALEQNIQALEENHQT 1578
+ Q +K EQ+ + QEQ++ + E+K Q E+K W +K E+ ++ EE Q
Sbjct: 112 KKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQG 171
Query: 1579 QEQE 1582
QE++
Sbjct: 172 QEEK 175
Score = 76.6 bits (187), Expect = 3e-13
Identities = 52/215 (24%), Positives = 117/215 (54%), Gaps = 17/215 (7%)
Query: 1374 LEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKAL-EQKGRDLEQKDTALEQKDKALEPK 1432
+ +E + ++ + +++E + + E +++Q++ + EQ+ + EQ++ EQ++K E +
Sbjct: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
Query: 1433 DKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIP 1492
+K E+++K EQ+ ++PE+K+K EQ + E++++ E K + +Q EK+
Sbjct: 61 EKMWEQEEKMWEQQ-RLPEQKEKMWEQDERLREKEERMREQK---------MWQQVEKM- 109
Query: 1493 EEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALE 1552
EK K ++K++ E K + E ++ EQ +K EQ+ + EQ++K+ E++++ E
Sbjct: 110 REKKKTQEEKMQEQEEK-----MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 164
Query: 1553 QKYWALGQKDEALEQNIQALEENHQTQEQESLVQE 1587
Q+ GQ+++ + E + + QE
Sbjct: 165 QEEKMQGQEEKMRDVEPAGGEAGEGSPQDNPTAQE 199
Score = 75.1 bits (183), Expect = 9e-13
Identities = 45/196 (22%), Positives = 115/196 (58%), Gaps = 7/196 (3%)
Query: 1350 KDRTSEQKKEPEPKDEVL-QQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKAL 1408
++R E++K+ ++E++ +Q++K E +E + ++ +++++E + + E + +Q++ +
Sbjct: 4 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 63
Query: 1409 EQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQK--DKIPEEKDKALEQKDTALEQ 1466
++ + ++ EQK+K E ++ E++++ EQK ++ + ++K Q++ EQ
Sbjct: 64 WEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQ 123
Query: 1467 KDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQ--KVRSVEHK--APEDTVAEMKDRD 1522
++K E ++ EQ++++ EQ+EK+ E+++K +Q K+R E K E+ + +++
Sbjct: 124 EEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAG 183
Query: 1523 LEQTDKAPEQKHQAQE 1538
E + +P+ AQE
Sbjct: 184 GEAGEGSPQDNPTAQE 199
Score = 73.6 bits (179), Expect = 3e-12
Identities = 42/182 (23%), Positives = 112/182 (61%), Gaps = 7/182 (3%)
Query: 1367 LQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKAL-EQKGRDLEQKDTALEQK 1425
++++++ E ++ + ++ + +++E + + E +++Q++ + EQ+ + EQ++ EQ+
Sbjct: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
Query: 1426 DKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQK--DKALEPKDKDLEQKDR 1483
+K E ++K + E+ + EQK+K+ E+ ++ E+++ EQK + + ++K Q+++
Sbjct: 61 EKMWEQEEK-MWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEK 119
Query: 1484 VLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKV 1543
+ EQ+EK+ E+++ +Q+ + E E+ + E +++ EQ +K EQ+ + Q Q++K+
Sbjct: 120 MQEQEEKMQEQEEMMWEQEEKMQEQ---EEKMWEQEEKMREQEEKMREQEEKMQGQEEKM 176
Query: 1544 SE 1545
+
Sbjct: 177 RD 178
Score = 71.2 bits (173), Expect = 1e-11
Identities = 47/194 (24%), Positives = 107/194 (55%), Gaps = 17/194 (8%)
Query: 1336 EDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALH 1395
E++ + E+K+ +++ EQ+++ ++E +Q++++ + ++++E +
Sbjct: 18 EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKM-------------WEQEEKMW 64
Query: 1396 VKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEK--DKALEQKDKIPEEK 1453
+ E + +Q + EQK + EQ + E++++ E K EK +K Q++K+ E++
Sbjct: 65 EQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQE 124
Query: 1454 DKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDK--ALDQKVRSVEHKAP 1511
+K EQ++ EQ++K E ++K EQ++++ EQ+EK+ E+++K ++K+R VE
Sbjct: 125 EKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGG 184
Query: 1512 EDTVAEMKDRDLEQ 1525
E +D Q
Sbjct: 185 EAGEGSPQDNPTAQ 198
Score = 62.4 bits (150), Expect = 6e-09
Identities = 48/185 (25%), Positives = 93/185 (50%), Gaps = 22/185 (11%)
Query: 1512 EDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQA 1571
E+ + E + + E+ + EQ+ + QEQ++K+ E++++ EQ E+ +Q
Sbjct: 4 EERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQ------------EEKMQE 51
Query: 1572 LEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGL-------- 1623
EE QE++ QE+K + + L E+ EK+ +E+L E+ + +
Sbjct: 52 QEEKMWEQEEKMWEQEEKMWEQQRLPEQK-EKMWEQDERLREKEERMREQKMWQQVEKMR 110
Query: 1624 EESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYW 1683
E+ QE + +EQEEK ++++ E +E +EE EQ+E E+ EQ+ +
Sbjct: 111 EKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK-M 169
Query: 1684 RGRED 1688
+G+E+
Sbjct: 170 QGQEE 174
Score = 44.7 bits (104), Expect = 0.001
Identities = 41/189 (21%), Positives = 84/189 (44%), Gaps = 17/189 (8%)
Query: 521 RELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSV 580
RE + E++ ++ EE +E+ + EQ + + ++ + EE +
Sbjct: 10 REKKMREEEEMMREQEEKMQEQEEKMREQEEK-MWEQEEKMQEQEEKMWEQEEK------ 62
Query: 581 PGLGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWE------EKKQREAERL 634
+ ++E M E++ +PE E+ +D L E E+ W+ EKK+ + E++
Sbjct: 63 --MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKM 120
Query: 635 PDRTEAREESEPEV--KEDVIEKAELEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVT 692
++ E +E E + +E+ +++ E + E+ E+EE + E Q ++ V
Sbjct: 121 QEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVE 180
Query: 693 PRSREAFGG 701
P EA G
Sbjct: 181 PAGGEAGEG 189
Score = 42.0 bits (97), Expect = 0.009
Identities = 35/171 (20%), Positives = 86/171 (50%), Gaps = 21/171 (12%)
Query: 309 KPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSE 368
+ K+++ + + + K+ ++EE + E +E E +++ + E+K E E
Sbjct: 10 REKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE-QEEKMQEQEEKMWEQEEKMWEQEE 68
Query: 369 KPPEKPAKPERVKT--ESSEALKAEKRKLIKDKVG---------KKHLKEKISKLEEK-- 415
K E+ PE+ + E E L+ ++ ++ + K+ KK +EK+ + EEK
Sbjct: 69 KMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQ 128
Query: 416 -------KDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKI 459
+ +EK + ++E+ ++++ R++E+K ++EEK + + +++ +
Sbjct: 129 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDV 179
Score = 41.6 bits (96), Expect = 0.011
Identities = 38/168 (22%), Positives = 69/168 (41%), Gaps = 14/168 (8%)
Query: 1629 QEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGRED 1688
+E R RE+E+K +++++E +E +EE EQ+E E+ EQ+ + W E
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62
Query: 1689 VALEQDTYWRELSC---ERKVWFPHE--------LDGQGARPHYTEERESTFLDEGPDDE 1737
+ +++ W + + K+W E + Q + RE E E
Sbjct: 63 MWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQE 122
Query: 1738 QEVPLREHATRSPWASDFKDFQESSPQKGLEVERWLAESPVGLPPEEE 1785
QE ++E W + K + +K E E + E + +EE
Sbjct: 123 QEEKMQEQ-EEMMWEQEEK--MQEQEEKMWEQEEKMREQEEKMREQEE 167
Score = 39.3 bits (90), Expect = 0.055
Identities = 28/130 (21%), Positives = 68/130 (52%), Gaps = 5/130 (3%)
Query: 336 KREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKL 395
+ EE + E K+ R E + + + E+K +E EK E+ K E E ++ ++ K+
Sbjct: 2 REEERMREREKKMREE-EEMMREQEEKMQEQEEKMREQEEK----MWEQEEKMQEQEEKM 56
Query: 396 IKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPE 455
+ + +EK+ + + ++++K +++ + +K+E +E+K + E+ R+ K +
Sbjct: 57 WEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQ 116
Query: 456 LKKISKPDLK 465
+K+ + + K
Sbjct: 117 EEKMQEQEEK 126
Score = 38.1 bits (87), Expect = 0.12
Identities = 44/229 (19%), Positives = 97/229 (42%), Gaps = 39/229 (17%)
Query: 354 KELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLE 413
+ + + EKK +E E E+ K + E E ++ ++ K+ + + + +EK+ + E
Sbjct: 5 ERMREREKKMREEEEMMREQEEKMQ----EQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
Query: 414 EKK-DKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVR 472
EK ++E+K +++R +K++ +++++ +KEE+ ++ K +V
Sbjct: 61 EKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQK-------------MWQQVE 107
Query: 473 KTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLT 532
K K K ++ ++ ++E+ E +E + E+
Sbjct: 108 KMREKKKTQEEKMQEQEEKMQEQEEMMWE-------------------QEEKMQEQEEKM 148
Query: 533 QDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVP 581
+ EE RE+ + EQ + G + D G A +G+P P
Sbjct: 149 WEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAG--GEAGEGSPQDNP 195
Score = 36.6 bits (83), Expect = 0.36
Identities = 37/161 (22%), Positives = 61/161 (37%), Gaps = 27/161 (16%)
Query: 1597 EEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPT 1656
EE+ E+ K M E+ E + E+ E+ QE + REQEEK W ++
Sbjct: 4 EERMREREKKMREEEEMMREQE-----EKMQEQEEKMREQEEKMW---------EQEEKM 49
Query: 1657 REEPAGEQKELAPAWEDTS--------PEQDNRYWRGRE-----DVALEQDTYWRELSCE 1703
+E+ ++ WE PEQ + W E + + + W+++
Sbjct: 50 QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKM 109
Query: 1704 RKVWFPHELDGQGARPHYTEERESTFLDEGPDDEQEVPLRE 1744
R+ E Q E+ E + E EQE + E
Sbjct: 110 REKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWE 150
Score = 36.6 bits (83), Expect = 0.36
Identities = 30/129 (23%), Positives = 65/129 (50%), Gaps = 12/129 (9%)
Query: 1342 WED-KVPGLKDRTSEQKKEPEPKDEVL------QQKDKTLEHKEVVEPK----DTAIYQK 1390
WE ++P K++ EQ + K+E + QQ +K E K+ E K + + ++
Sbjct: 71 WEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQ 130
Query: 1391 DEALHVKNEAVKQQDKAL-EQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKI 1449
+E + + E +++Q++ + EQ+ + EQ++ EQ++K ++K + + E +
Sbjct: 131 EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEAGEGS 190
Query: 1450 PEEKDKALE 1458
P++ A E
Sbjct: 191 PQDNPTAQE 199
Score = 35.8 bits (81), Expect = 0.61
Identities = 28/122 (22%), Positives = 59/122 (48%), Gaps = 15/122 (12%)
Query: 333 KLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEK 392
+L +++E + E + R KE E+K + EK EK E E E ++ ++
Sbjct: 75 RLPEQKEKMWEQDERLRE---KEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQE 131
Query: 393 RKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDT 452
+ + + + +EK+ + EEK ++++++ R++E+K +EEK +D
Sbjct: 132 EMMWEQEEKMQEQEEKMWEQEEKMREQEEKM------------REQEEKMQGQEEKMRDV 179
Query: 453 KP 454
+P
Sbjct: 180 EP 181
>gi|188536004 zinc finger protein 469 [Homo sapiens]
Length = 3925
Score = 94.4 bits (233), Expect = 1e-18
Identities = 252/1073 (23%), Positives = 341/1073 (31%), Gaps = 240/1073 (22%)
Query: 1775 ESPVGLPPE------EEDKLTRSPFEIISPPA---SPPEMVGQRVPSAPGQESPIPDPKL 1825
E P G PP + ++ SP PP +P + A GQ + P+
Sbjct: 4 ERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEA 63
Query: 1826 MPHMKN--EPTTPSWLADIPPWVPKDRPLPPAP--LSPAPGPPTPA--PESHTPAPFSWG 1879
P E PS P P R P P SP P A E P + G
Sbjct: 64 QPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILG 123
Query: 1880 TAE------YDSVVAAVQEGAAELE--GGPYSP-LGKDYRKAEGEREEEGRAEAPDKSSH 1930
A D Q AA+L P P G R E + AE
Sbjct: 124 IASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRC 183
Query: 1931 SSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPL 1990
+ P + S T P T R P P P + G P P P
Sbjct: 184 FQEPPSSFTSTNYTSPSATP---RPPAPGPPQSR-------------GTSPLQPGSYPEY 227
Query: 1991 GAAG--DWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDTPT-----FSYAALAGPTV 2043
A+G WPP + + + G N PI S +P F + AL G +
Sbjct: 228 QASGADSWPP--AAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGAST 285
Query: 2044 PPRPEP--------GPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSPSPKE 2095
P P GP + P P + GP+ PL P + +PSP
Sbjct: 286 KPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAV-GTGPAYPL--------PTQPAPSPLP 336
Query: 2096 SGRSHWDDSTSDSELEKGAREQPEKEAQSPSP-PHPIPMGSPTLWPETEAHVSPPLDSHL 2154
+ S+L GA P +P P + + PE L S
Sbjct: 337 CYQGQPGGLNRHSDLS-GALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTR 395
Query: 2155 GP--ARPSLDFPASAFGFSSLQ--------------PAPPQLPSPAEPRSAPCGSLAFSG 2198
GP + P FP A+ S + P P +LP +P +AP +
Sbjct: 396 GPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPT----- 450
Query: 2199 DRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQ---------LPS--PSSPGAPLLSNL 2247
PG P + +P LPQ LP+ PS G +LS L
Sbjct: 451 ------PPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRL 504
Query: 2248 PRPASPALSEGSSSEATTPVISSVAERFS-PSLEAAEQES-------GELDPGMEP---- 2295
P PA +G S A + R P++ +++ S G DPG +P
Sbjct: 505 PFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFG 564
Query: 2296 ------AAHSLWDLTP--LSPAPPASLDLALAPAPSLPGDMGDGILPCHLECSEAATEK- 2346
+ H L P + A P+ L +PA + G + P + ++E+
Sbjct: 565 VAQPQVSPHGTPSLPPPRVVGASPSESPLP-SPATNTAGSTCSSLSPMSSSPANPSSEES 623
Query: 2347 -------PSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAACPAWERGAWPEGAER 2399
PS F P G SP PP P + E A A P G EGA +
Sbjct: 624 QLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQ 683
Query: 2400 SSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSF--LNPPL 2457
+T E P GG G P + P P H S S L+ L
Sbjct: 684 CLE-ETPFPHEGPEVGRGGLQGFPRAPPPY-----------PTHHFSLSSASLDQLDVLL 731
Query: 2458 PPSIDDRDLSTEEVRLVGRG------GRRRVG---GPGTTGGPCPVTDETPPTSASD--- 2505
DR+ S+ L R R + G PG G P P P A
Sbjct: 732 TCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLL 791
Query: 2506 --------SGSSQSDS-DVPPETEECPSITA--------------EAALDS--------- 2533
+G +Q++ D P T PS+ A +A LDS
Sbjct: 792 SHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGM 851
Query: 2534 -------DEDGDFLPVDKAGGVSGTHHPRPGHD-------------PPPLPQPDPRPSPP 2573
+ D F+ V SG P GH PPPLP P P P
Sbjct: 852 EYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTP 911
Query: 2574 RP--------------DVCMADPEGLSSESGRVERLREKEKVQGR----------VGRRA 2609
RP + +A E + GR +R ++ K+ + G
Sbjct: 912 RPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGG 971
Query: 2610 PGKAKPASPARRLDLRGKRSPTPGKGPADRA--SRAPPRPRSTTSQVTPAEEK 2660
G+A P RR D G+R P + P +A SRA P PR + P E +
Sbjct: 972 GGRASGLRP-RRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETR 1023
Score = 59.7 bits (143), Expect = 4e-08
Identities = 216/936 (23%), Positives = 303/936 (32%), Gaps = 158/936 (16%)
Query: 1800 ASPPEMVGQRVPSAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPA-PLS 1858
A PP+ + VPS P P P + + P PS D+ + PP +
Sbjct: 1457 ADPPQ---KTVPSDP------PYPSFLLLEEVSPMLPSHFPDLSGGKVLSKTCPPERTVV 1507
Query: 1859 PAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGEREE 1918
P P P S +E + +Q+ ELE ++ +R +
Sbjct: 1508 PGAAPSLPGKGSGCSVALMSHLSEDE---LEIQKLVTELE-------------SQLQRSK 1551
Query: 1919 EGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQYADIYEQMMLT- 1977
+ R AP + + + V T P Q Q P E +F AD+ T
Sbjct: 1552 DTRG-APRELAEAESVGRVELGTGTEPPSQRRTCQ---ATVPHEDTFSAADLTRVGESTA 1607
Query: 1978 ---GLGPACPTREPPLGA-AGDWPPCLSTKEAAAGRNTSAEKELSS--PISPKSLQSDTP 2031
G A T E G G WP S A A+++L S P SP+
Sbjct: 1608 HREGAESAVATVEAVQGRPGGTWPCPASFHPGHAALLPCAQEDLVSGAPFSPRGANFH-- 1665
Query: 2032 TFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLN-GNILSCSPDRRS 2090
F AG + + G + P P SK P P L+ G++ CSPD+
Sbjct: 1666 -FQPVQKAGAS-----KTGLCQAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQEL 1719
Query: 2091 PSPKESGRSHWDDSTSDSEL-----------EKGAREQPEKEAQSPSPPHPIPMGSPTLW 2139
PK + +S L E G +QP + A P P GSP +
Sbjct: 1720 SFPKNKEAASSQESEDSLRLLPCEQRGGFLPEPGTADQPHRGA-----PAPEAFGSPAV- 1773
Query: 2140 PETEAHVSPPLDSHLGPARPSLD----FPAS----AFGFSSLQPAPPQLPSPAEP----- 2186
H++P L + G P LD F AS A G S+ + P+ P
Sbjct: 1774 -----HLAPDL-AFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEGN 1827
Query: 2187 RSAPCG--SLAFSGDRALALAPGP-PTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPL 2243
AP G SL R L P P P + ++ P+L + QL
Sbjct: 1828 EFAPAGASSLTAPRGREAWLVPVPSPACVSNTHPSRRSQDPALSPPIRQL---------- 1877
Query: 2244 LSNLPRPASPALSEG-SSSEATTPVISSVAERFSPS-LEAAEQESGELDPGMEPAAHSLW 2301
LP P +G + TP S R +PS LE E G++ G +
Sbjct: 1878 --QLPGPGVAKSKDGILGLQELTPAAQS-PPRVNPSGLEGGTVEGGKVACGPAQGSPGGV 1934
Query: 2302 DLTPLSPAPPASLDL-------ALAPAPSLPGDMGDGILPCHLECSEAATEKPSPFQVPS 2354
+T L L L L A G L S T+ + S
Sbjct: 1935 QVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHASVNA-S 1993
Query: 2355 EDCAANGPTETS---PNPPGPAPAKAENEEAAACPAWERGAWPEGAERSSRPDTLLSPEQ 2411
A GPTE + G A + EEA P+ P R S L +
Sbjct: 1994 PKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPS------PPSPNRESLALALTAAHS 2047
Query: 2412 PVCPAGGSGG--PPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPP----LPPSIDD-- 2463
GS G P ++SP + P P G+L+ +P +P S+
Sbjct: 2048 ----RSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTSAAHMPCSLGPLP 2103
Query: 2464 -RDLSTEEVRLVGRGGRRRVGGPGTTGGPCP-----VTDETPPTSASDSGSSQSDSDVPP 2517
D T R G G + P P P + P +D + +D+
Sbjct: 2104 REDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEADGVQATTDTGAED 2163
Query: 2518 ETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPP---R 2574
PS+T P D ++G G P DP PP
Sbjct: 2164 SPVAPPSLTTS------------PCDPKEALAGCLLQGEGS-----PLEDPSSWPPGSVS 2206
Query: 2575 PDVCMADPEGLSSESGRVERLREKEKVQGRVGR-RAPGKAKPASPARRLDLRGKRS-PTP 2632
C + + R+ KEK+ GR +P A SP+ + G S PT
Sbjct: 2207 AVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTG 2266
Query: 2633 GKGPADRASRAP-PRPRSTTSQVTPAEEKDGHSPMS 2667
+ A R P P+ R P GHS S
Sbjct: 2267 DEAQAGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYS 2302
Score = 54.7 bits (130), Expect = 1e-06
Identities = 115/460 (25%), Positives = 170/460 (36%), Gaps = 79/460 (17%)
Query: 2222 KAPSLDSSLPQ------LPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERF 2275
KA +L+ +LP +P S+PG PR +SP LSEGS P + +
Sbjct: 3434 KARALEGTLPSKRRRVAMPG-SAPGPGEDRPPPRGSSPILSEGS-----LPALLHLCSEV 3487
Query: 2276 SPSLEAAEQESGELDPGMEPAAHSLWDLTPLS---PAPPASLDLALAPAPSLPGD-MGDG 2331
+PS E+ L+ ++P H + S PP S L+P P+ D GD
Sbjct: 3488 APSTTKGWPET--LERPVDPVTHPIRGCELPSNHQECPPPS----LSPFPAALADGRGDC 3541
Query: 2332 ILPCHLEC--SEAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAACPAWE 2389
L LE +EA+ P P + A+ P PG AE + A + +
Sbjct: 3542 ALDGALERPENEASPGSPGPLLQQALPLGASLPR------PGARGQDAEGKRAPLVFSGK 3595
Query: 2390 R---GAWPEGAERSSRPDTLLSPEQPVCPAG--GSGGPPSSASPEVEAGPQGCATEPRPH 2444
R GA A + D LL E+ V + GGP + P GC + +
Sbjct: 3596 RRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDR 3655
Query: 2445 RGELSPS-FLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPP-TS 2502
+PS L P+ P L+ E+ GT G P T + P S
Sbjct: 3656 SAASTPSKALKFPVHPRKAVGSLAPGEL------------ARGTENGMKPATPKAKPGPS 3703
Query: 2503 ASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPP 2562
+ SGS + + ++ P A L S+ + T +P P
Sbjct: 3704 SQGSGSPRPGTKTGGGSQPQP---ASGQLQSE--------------TATTPAKPSF-PSR 3745
Query: 2563 LPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASPARRL 2622
P P+ P+ + C P + E G L KEK + R+ K + PAR
Sbjct: 3746 SPAPERLPARAQAKSCTKGPRE-AGEQGPHGSLGPKEKGESSTKRK---KGQVPGPARSE 3801
Query: 2623 DLR--GKRSPTPGKGPADRASRAPPRPRSTTSQVTPAEEK 2660
+ G+ P K P PR ++T S+V P + K
Sbjct: 3802 SVGSFGRAPSAPDKPP------RTPRKQATPSRVLPTKPK 3835
Score = 47.4 bits (111), Expect = 2e-04
Identities = 178/777 (22%), Positives = 249/777 (32%), Gaps = 146/777 (18%)
Query: 1742 LREHATRSPWASDFKDFQESSPQKGLEVERWLAE--SPVGLPPEEEDKLTRSPFEIISPP 1799
LREHA R + P GLE +A + + P + + RS + P
Sbjct: 3166 LREHAVRFARRGQARRSLGDLPG-GLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAGSP 3224
Query: 1800 ASPPEMVGQRVPSAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSP 1859
P G+ +PG+ + P ++ P+ P A P +
Sbjct: 3225 GDPWGQEGEAKKDSPGERAK-------PRARSTPSNPDGAA-----TPDSASATALADAG 3272
Query: 1860 APGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGEREEE 1919
+PGPP P +P+P W E L+ P KD
Sbjct: 3273 SPGPPRTTP---SPSPDPWAGGE------------PLLQATPVHEACKD----------- 3306
Query: 1920 GRAEAPDKSSH--SSKVPEASKSH---ATTEPEQTEPEQREPTPYPDERSFQYADIYEQM 1974
P + H + P+ K A P++ R P YP+
Sbjct: 3307 -----PSRDCHHCGKRFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEHGE---------- 3351
Query: 1975 MLTGLGPACPTREPPLGAAGDWPPC---------LSTKEAAAGRN-TSAEKELSSPISPK 2024
+L LG A E P C + A + N T A+KE K
Sbjct: 3352 LLAHLGGAHGLLERPELQHTPLYACELCATVMRIIKKSFACSSCNYTFAKKEQFDRHMNK 3411
Query: 2025 SLQSDTPTFSYAALAGPTVPPRPE----------------PGPSMEPSLTPPAVPPR--A 2066
L+ F++ + P P + PG + P P PPR +
Sbjct: 3412 HLRGGRQPFAFRGVRRPGAPGQKARALEGTLPSKRRRVAMPGSAPGPGEDRP--PPRGSS 3469
Query: 2067 PILSKGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPS 2126
PILS+G P L +P P+ R D T E P + P
Sbjct: 3470 PILSEGSLPALLHLCSEVAPSTTKGWPETLERP-VDPVTHPIR----GCELPSNHQECP- 3523
Query: 2127 PPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFP--ASAFGFSSLQPAPPQLPSPA 2184
PP P + + + L+ A P P A + P P A
Sbjct: 3524 PPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDA 3583
Query: 2185 EPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLE---VTKAPSLDSSLPQLPSPSSP-G 2240
E + AP L FSG R APG R D + E + K + SS + S P G
Sbjct: 3584 EGKRAP---LVFSGKRR---APGARGRCAPDHFQEDHLLQKEKEVSSS--HMVSEGGPRG 3635
Query: 2241 APLLSNLPRPASPALSEGSSSEATTPVISSVAERF--SPSLEAAEQESGELDPGMEPAAH 2298
+ +PA S S A+TP S A +F P GEL G E
Sbjct: 3636 TFHKGSATKPAGCQSSSKDRSAASTP---SKALKFPVHPRKAVGSLAPGELARGTE---- 3688
Query: 2299 SLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLECSEAATEKPSPFQVPSEDCA 2358
+ PA P + P PS G G + + +P+ Q+ SE
Sbjct: 3689 -----NGMKPATPKA-----KPGPS---SQGSGSPRPGTKTGGGSQPQPASGQLQSE--T 3733
Query: 2359 ANGPTETSPNPPGPAPAK-AENEEAAACPAWERGAWPEGAERSSRP------DTLLSPEQ 2411
A P + S PAP + +A +C R A +G S P T Q
Sbjct: 3734 ATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQ 3793
Query: 2412 PVCPAG----GSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPPLPPSIDDR 2464
PA GS G SA + P+ AT R + P+ N P PP + R
Sbjct: 3794 VPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQR 3850
Score = 43.1 bits (100), Expect = 0.004
Identities = 178/789 (22%), Positives = 246/789 (31%), Gaps = 176/789 (22%)
Query: 1984 PTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQS--DTPTFSYAALAG- 2040
PT PP L+ + +G + SSP K L + D+P S LA
Sbjct: 2026 PTPSPPSPNRESLALALTAAHSRSGSEGRTPERASSPGLNKPLLATGDSPAPSVGDLAAC 2085
Query: 2041 ---PT--------VPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRR 2089
PT + P P P PS + + P PP +L+CSP
Sbjct: 2086 APSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWA 2145
Query: 2090 SPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPHPI-----------PMGSPTL 2138
+ ++ D DS + P SP P P+ P+
Sbjct: 2146 PLEEADGVQATTDTGAEDSPV------APPSLTTSPCDPKEALAGCLLQGEGSPLEDPSS 2199
Query: 2139 WPETEAHVSPPLDSHLG--PARPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAF 2196
WP VS +H G P +L P + L +P + SP
Sbjct: 2200 WP--PGSVSAVTCTHSGDTPKDSTLRIPEDS-RKEKLWESPGRATSP------------- 2243
Query: 2197 SGDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPLLSN---LPR---- 2249
A A++P R LP P P S GAP +N +PR
Sbjct: 2244 --PLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPG-PDPQSRGAPPHTNPDRMPRGHSS 2300
Query: 2250 --PASPALSEGSSSEATTPVISSVAERFSPSLEAAEQES-----GEL--------DPGME 2294
P++ A +A T V + P+L+ A +S GE+ DPG
Sbjct: 2301 YSPSNTARLGHREGQAVTAVPTE-----PPTLQGAGPDSPACLEGEMGTSSKEPEDPGTP 2355
Query: 2295 PAAHSLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLECSEAATEKPSPFQVPS 2354
S P P L L APS S FQ S
Sbjct: 2356 ETGRSGATKMPRVTCPSTGLGLGRTTAPS---------------------STASDFQSDS 2394
Query: 2355 EDCAANGPTETSPNPP-GPAPAKAENEEAAACPA-WERGAWPEGAERSSRPDTLLSPEQP 2412
N +T P GP K + PA E G W + P ++ E
Sbjct: 2395 PQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQW-----KGQAPHGPVTCE-- 2447
Query: 2413 VCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRG---ELSPSFL--NPPLPPSIDDRDLS 2467
VC A GP S A + RPH G E SP+ L PL P
Sbjct: 2448 VCAASFRSGPGLSRHK---------ARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPP 2498
Query: 2468 TEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPPTSASD----SGSSQSDSDVPPE-TEEC 2522
++ V G+ R + G P VT P + + GS S PP TE
Sbjct: 2499 RKKSHRV--SGKERPN--HSRGDPSHVTQPPPAQGSKEVLRAPGSPHSQQLHPPSPTEHE 2554
Query: 2523 PSITAEAAL---DSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRPDVCM 2579
+ A+ D + + P P D P
Sbjct: 2555 VDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVDSP------------------ 2596
Query: 2580 ADPEGLSSESG---RVERLREKEKV--------QGRVGRRAPGKAK-PASPARRLDLRG- 2626
+ EG S++ R RLRE+ + GR R +P A ASP+ L + G
Sbjct: 2597 SHSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYAASPSHCLSVEGG 2656
Query: 2627 --------KRSPTPGKGPADRASRAPPRPRSTTSQVTPAEEKDGHSPMSKGLVNGLKAGP 2678
R T G G + A A + + T A++ G + G ++G G
Sbjct: 2657 PEADGEQPPRLATLGPGVMEGA--AETDQEALCAGETGAQKPPGDRMLCPGRMDGAALGE 2714
Query: 2679 MALSSKGSS 2687
KG+S
Sbjct: 2715 QPTGQKGAS 2723
Score = 41.6 bits (96), Expect = 0.011
Identities = 110/440 (25%), Positives = 146/440 (33%), Gaps = 61/440 (13%)
Query: 2046 RPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDST 2105
R E +E + P P+ P K G+ +P+ S GRS
Sbjct: 1089 RGEKRKEVELTQGPREDEPQKP--RKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGP 1146
Query: 2106 SDSELEKGA--REQPEKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDF 2163
S S LE GA RE K A PS P+ PT +E RPSLDF
Sbjct: 1147 SRS-LETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEE------------TRPSLDF 1193
Query: 2164 PASAFGFSSLQPAPPQLPSPAEP-RSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEVTK 2222
P A + + + P E RS P G L P P +RHD
Sbjct: 1194 PQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTP-KP 1252
Query: 2223 APSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTP--VISSVAERFSPSLE 2280
+ SL ++ P SP+ LL +P A P ++ VA S +
Sbjct: 1253 SGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTACP 1312
Query: 2281 AAEQESGELDP-GMEPAAHSLWDL-TPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLE 2338
S ++ G +PA + L P++ P + P D+ L
Sbjct: 1313 KPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFL----- 1367
Query: 2339 CSEAATEKPSPFQVP--SEDCAANGPTET---SPNPPGPAPAKAENEEAAACPAWERGAW 2393
E KPS P S C + P P P AE E R A
Sbjct: 1368 --EELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPG-------RAAS 1418
Query: 2394 PEGAERSSRPDTLLSPEQPVCPAGGSGGPP--SSASPEVEAG-PQGCATEPR-------P 2443
P E SS L P+ PV PP S S ++G P CA P+ P
Sbjct: 1419 PPTLESSS-----LFPDLPV----DRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPP 1469
Query: 2444 HRGELSPSFLNPPLPPSIDD 2463
+ L ++P LP D
Sbjct: 1470 YPSFLLLEEVSPMLPSHFPD 1489
Score = 38.5 bits (88), Expect = 0.094
Identities = 60/276 (21%), Positives = 93/276 (33%), Gaps = 38/276 (13%)
Query: 972 PGEPALGEAEERCLSPDDSTVKMASPP--PSGPPSATHTPFHQSPVEEKSEPQDFQEADS 1029
PGE G A ++ D ++AS P PS PP +TP ++ + +EA
Sbjct: 2 PGERPRG-APPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTT-------KGAREAGG 53
Query: 1030 WGDTKRTPGVGKEDAAEETVKPGPEEGTLEKEE-------KVPPPRSP---------QAQ 1073
P A + +KP G + PP RSP +A+
Sbjct: 54 QAQAMELPEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAE 113
Query: 1074 EAP-----VNIDEGLTGCTIQLLPAQDKAIVFEIMEAGEPTGPILGAEALPGGLRTLPQE 1128
+P + I T T+ P + ++ E P GP GA PG LP+
Sbjct: 114 GSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPG----LPRT 169
Query: 1129 PGKPQKDEVLRYPDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRWPE 1188
+P +E+ E S + + SP + P P P L +PE
Sbjct: 170 EAQPAAEEL---GFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPE 226
Query: 1189 VSPEDTQSLSLSEESPSKETSLDVSSKQLSPESLGT 1224
S + E+ + V + P G+
Sbjct: 227 YQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGS 262
Score = 37.7 bits (86), Expect = 0.16
Identities = 184/849 (21%), Positives = 276/849 (32%), Gaps = 155/849 (18%)
Query: 568 PPSTAIQGTPPSVPGLGQ----------EEHVMKEKELVPEVPEE-QGSKDRGLDSGAET 616
P T + G PS+PG G E ++ ++LV E+ + Q SKD GA
Sbjct: 1502 PERTVVPGAAPSLPGKGSGCSVALMSHLSEDELEIQKLVTELESQLQRSKD---TRGAPR 1558
Query: 617 E-EEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIEKAELEEMEEVHPSDEEEEDAT 675
E E ++ + P + + + P ED A+L + E S E A
Sbjct: 1559 ELAEAESVGRVELGTGTEPPSQRRTCQATVPH--EDTFSAADLTRVGE---STAHREGAE 1613
Query: 676 KAEGFYQKHMQEPLKVTPRSREAFGGRELGLQGKAPEKETSLFLSSLTTPAGATEHVSYI 735
A + P P G L P + L + +P GA H +
Sbjct: 1614 SAVATVEAVQGRPGGTWPCPASFHPGHAALL----PCAQEDLVSGAPFSPRGANFHFQPV 1669
Query: 736 QDETIPGYSETEQTISDEEIHDEPEERPAPPRFHTSTYDLPGPEGAGPFEASQPADSAVP 795
Q G S+T + E PP+ D+ PE + QP
Sbjct: 1670 QK---AGASKTGLC--------QAEGDSRPPQ------DVCLPE-----PSKQPGPQLDA 1707
Query: 796 ATSGKVYGTPETELTYPTNIVAAPLAEEEHVSSATSITECDKLSSF-------------A 842
+ K +P+ EL++P N AA E E + + C++ F A
Sbjct: 1708 GSLAKC--SPDQELSFPKNKEAASSQESE---DSLRLLPCEQRGGFLPEPGTADQPHRGA 1762
Query: 843 TSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEATQGLDYVPSAGTISPTSSLE 902
+ S A AP G + LD +S + A QG + G + PT+
Sbjct: 1763 PAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRP 1822
Query: 903 EDKGFKSPPCEDFSVTGESEKRGEIIGKGLSGERAVEEEEEETANVEMSEKLCSQYGTPV 962
+G + P S+T +G +N S + SQ P
Sbjct: 1823 GFEGNEFAPAGASSLTAP---------RGREAWLVPVPSPACVSNTHPSRR--SQ--DPA 1869
Query: 963 FSAPGHALHPGEPALGEAEERCLSPDDSTVKMASPP---PSGPPSATHT-------PFHQ 1012
S P L P + ++++ L + T SPP PSG T P
Sbjct: 1870 LSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTVEGGKVACGPAQG 1929
Query: 1013 SP--VEEKSEP-----QDFQEADS-W---GDTKRTPGVGKEDAAEETVKPGPEEGTLEKE 1061
SP V+ + P Q EAD W G ++T G G + L+ E
Sbjct: 1930 SPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTAN-------------QLQPE 1976
Query: 1062 EKVPPPRSPQAQEAPVNIDEGLTGCT---IQLLPAQDKAIVFEIMEAGEPT--GPILGAE 1116
V P + + LTG T + L + + E EPT P E
Sbjct: 1977 NGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRE 2036
Query: 1117 ALPGGLRTLPQEPGKPQKDEVLRYPDRSLSP-----------EDAESLSVLS--VPSPDT 1163
+L L G R P+R+ SP A S+ L+ PSP +
Sbjct: 2037 SLALALTAAHSRSGSEG-----RTPERASSPGLNKPLLATGDSPAPSVGDLAACAPSPTS 2091
Query: 1164 ANQEPTPKSPCGLTEQYLHKDRWP-------------EVSPEDTQSLSLS------EESP 1204
A P P + R P Q L+ S EE+
Sbjct: 2092 AAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQLLACSPAWAPLEEAD 2151
Query: 1205 SKETSLDVSSKQLSPESLGTLQFGELNLGKEEMGHLMQAEDTSHHTAPMSVPEPHAATAS 1264
+ + D ++ SP + +L + + G L+Q E S P S P + +
Sbjct: 2152 GVQATTDTGAED-SPVAPPSLTTSPCDPKEALAGCLLQGEG-SPLEDPSSWPPGSVSAVT 2209
Query: 1265 PPTDGTTRYSAQTDITDDSLDRKSPASSFSHSTPSGNGKYLPGAITSPDEHILTPDSSFS 1324
G T + I +DS K S ++P G P TP +
Sbjct: 2210 CTHSGDTPKDSTLRIPEDSRKEKLWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEA 2269
Query: 1325 KSPESLPGP 1333
++ LPGP
Sbjct: 2270 QAGRGLPGP 2278
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 94.0 bits (232), Expect = 2e-18
Identities = 242/1001 (24%), Positives = 322/1001 (32%), Gaps = 144/1001 (14%)
Query: 1789 TRSPFEIISPPASPPEMVGQRVPSAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPK 1848
TRS PAS P G R AP ++ P P P + T P L +
Sbjct: 80 TRSAGTSSRNPASRPPASG-RGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 138
Query: 1849 DRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKD 1908
+ + A G T AP+ + A ++ + G P + +
Sbjct: 139 EETV-------ARGKATEAPKRSALS------------AGARRDTSGPTPGTPSPAMARR 179
Query: 1909 YRKAEGE----REEEGRAEAPDKSSHSSKVPEASKSHATTEPE---QTEPEQREPTPYPD 1961
R A E R P V AS+ H+TTEP + P P
Sbjct: 180 SRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE-HSTTEPSPAARRRPSAGGGLQRPA 238
Query: 1962 ERSFQY--------ADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLST--KEAAAGRNT 2011
RS A T PA P++ P G PP ++ K+AA
Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 298
Query: 2012 SAEKELSSPISPKSLQSDTPTFSYAALAGP-TVPPRPE---------PGPSMEPSL---- 2057
+ L++P + P AA P T+PP P P PS PSL
Sbjct: 299 LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLP 358
Query: 2058 TPPAVPPR-------APILSKGPS----PPLNGNILSCSPDRRSPSPKESGRSHWDDSTS 2106
+PPA PP P + PS PP+ SP ++P P S +TS
Sbjct: 359 SPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP-PSPLALSSLQATTS 417
Query: 2107 ---------DSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPA 2157
S L R Q + SPS P P SP L SPPL + L PA
Sbjct: 418 LGSPTLQATHSFLTMSPR-QTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPA 476
Query: 2158 RPSLDFPASAF---GFSSLQPAPPQLP------SPAEPRSAPCGSLAFSGDRALALAPGP 2208
L P + SSL PQ P P E +S+ + +L P
Sbjct: 477 VSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE 536
Query: 2209 PTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVI 2268
+ L+ AP + P L +P P L P P + E SS AT P
Sbjct: 537 NLPSLAPPPLQTASAP---LTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQ 593
Query: 2269 SSVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPLS--PAPPASLDLA--LAPAPSL 2324
+ A SP L+ P A L PL P+PPAS L+ P+P
Sbjct: 594 APPA-LASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQA 652
Query: 2325 PGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAK--AENEEA 2382
P L HL + + P Q P A+ P S PP AP A +
Sbjct: 653 P-----NALAVHLLQAPFSPPPSPPVQAPFSP-PASPPVSPSATPPSQAPPSLAAPPLQV 706
Query: 2383 AACPAWERGAWPEGAERSSRPDTLLSPEQPVCPA-------GGSGGPPSSASPEVEAGPQ 2435
P P P L +P V P+ S PP P + A P
Sbjct: 707 PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPL 766
Query: 2436 GCATEPRPHRGELSPSFLNPP-LPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPV 2494
P P +SP PP PP++ L G+ P + P+
Sbjct: 767 QVPPSP-PASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQ----APFSPSASLPM 821
Query: 2495 TDETPPTSASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHP 2554
+ P + + VPP P++ A + P G T
Sbjct: 822 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG-----PDTSVSGPRLTLAL 876
Query: 2555 RPGHDPPPLPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEK-VQGRVGRRAPGKA 2613
PG PPP P P + PD+ SS + E LR + +G P A
Sbjct: 877 APG--PPPPPSRSPSSTLSGPDLAGHS----SSATSTPEELRGYDSGPEGGAAASPPPDA 930
Query: 2614 KPAS---------PARRLDLRGKRS------PTPGKGPADRASRAPPRPRSTTSQVTPAE 2658
+ A+ PA L RG P G G AD ++ P
Sbjct: 931 ELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGA 990
Query: 2659 EKDGHSPMSKGLVNGLKAGPMALSSKGSSGAPVYVDLAYIP 2699
G SP + G AG A SS +P L +P
Sbjct: 991 LDPGPSPGTSGGKAAAGAGAGA-----SSRSPKQARLGELP 1026
Score = 81.6 bits (200), Expect = 1e-14
Identities = 133/547 (24%), Positives = 173/547 (31%), Gaps = 125/547 (22%)
Query: 1767 LEVERWLAESPVGLPPEEEDKLTRSPFEIISPPASPPEMVGQRVPSAPGQESPIPDPKLM 1826
LE A P+ PP LT P E S A+PP + S P Q +P P L
Sbjct: 558 LETPPCPAPCPLQAPPSP---LTTPPPETPSSIATPPPQAPPALASPPLQ--GLPSPPLS 612
Query: 1827 PHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTAEYDSV 1886
P LA PP P LPP P+P P TP+P
Sbjct: 613 P-----------LATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSP----------- 650
Query: 1887 VAAVQEGAAELEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATTEP 1946
A A L P+SP +P + S S + T P
Sbjct: 651 -QAPNALAVHLLQAPFSP-----------------PPSPPVQAPFSPPASPPVSPSATPP 692
Query: 1947 EQTEPEQREPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAA 2006
Q P P P P PP+ + PP AA
Sbjct: 693 SQAPPSLAAPPLQV--------------------PPSPPASPPMSPSATPPPQAPPPLAA 732
Query: 2007 AGRNTSAEKELSSPISPKSLQSDTPTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRA 2066
S P+SP + T PPR P + P PP+ P
Sbjct: 733 PPLQVPPSPPASPPMSPSA----------------TPPPRVPPLLAAPPLQVPPSPPASL 776
Query: 2067 PILSKGPSPPLNGNILSCSPDRRSPSPKES--GRSHWDDSTSDSELEKGAREQPEKEAQS 2124
P+ PP L+ P + PSP S G++ + S S P +
Sbjct: 777 PMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS----------LPMSPLAT 826
Query: 2125 PSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFPASAFGFS-SLQPAPPQLPSP 2183
P P P + +P L SP L + P P D S + +L P PP P P
Sbjct: 827 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP--PPP 884
Query: 2184 AEPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLE--VTKAPSLDSSL----------- 2230
+ S+ +G + A + P +D E +P D+ L
Sbjct: 885 SRSPSSTLSGPDLAGHSSSATST-PEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 943
Query: 2231 --PQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFSPSLEAAEQESGE 2288
P L +PGAPL P PA GS+ T + E P E+A G
Sbjct: 944 PAPPLAFRGAPGAPL------PWPPATGPGSADGLCT-----IYETEGP--ESATPAPGA 990
Query: 2289 LDPGMEP 2295
LDPG P
Sbjct: 991 LDPGPSP 997
Score = 60.8 bits (146), Expect = 2e-08
Identities = 115/456 (25%), Positives = 160/456 (35%), Gaps = 80/456 (17%)
Query: 2036 AALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSP------PLNGNILSCSPDRR 2089
AA A + PRP P P +TP A+ + G P + G + S R
Sbjct: 18 AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA 77
Query: 2090 SPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSP----------PHPIPMGSPTLW 2139
P+ + +G S + ++ +G R P K SP P P P+G L
Sbjct: 78 GPT-RSAGTSSRNPASRPPASGRGERAPPAKNT-SPGPVSSPGRASGTTRPGPLGQKGLR 135
Query: 2140 PETEAHVSPPLDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPA-EPRSAPCGSLAFSG 2198
E V+ + P R +L SA P PSPA RS G+
Sbjct: 136 ISAEETVARGKATE-APKRSAL----SAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP 190
Query: 2199 DRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEG 2258
A + P PPT ++ + + S PS+ G L RPAS +LS
Sbjct: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG-----GLQRPASRSLS-S 244
Query: 2259 SSSEATTPVISSVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLAL 2318
S++ ++P S + R +P A +P L L P PP D A
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPS---------QPKPKGLQALRPPQVTPPRK-DAAP 294
Query: 2319 APAPSLPGDMGDGILPCHLECSEAATEKPSPFQV----PSEDCAANGPTETSPNPPGPAP 2374
A P L S AT PS + P ++ A P P+PP P
Sbjct: 295 ALGP--------------LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATP 340
Query: 2375 AKAENEEAAACPAWERGAWPEGAERSSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGP 2434
+A P+ + TL SP P P S PPS +P ++A P
Sbjct: 341 LPLAPPSPSAPPSLQ---------------TLPSP--PATPP--SQAPPSMTTPPMQAPP 381
Query: 2435 QGCATEP--RPHRGELSPSFLNPPLPPSIDDRDLST 2468
P PH SPS PP P ++ +T
Sbjct: 382 SLQTIPPIQVPH-SLTSPSLQAPPSPLALSSLQATT 416
Score = 56.6 bits (135), Expect = 3e-07
Identities = 89/386 (23%), Positives = 122/386 (31%), Gaps = 64/386 (16%)
Query: 1773 LAESPVGLPPEEEDKLTRSPFEIISPPASPPEMVGQRVPSAPGQESPIPDPKLMPHMKNE 1832
LA P+ +PP SP PP +PP + + P SP P + P
Sbjct: 699 LAAPPLQVPPSPPASPPMSP-SATPPPQAPPPLAAPPLQVPP---SPPASPPMSPSATPP 754
Query: 1833 PTTPSWLADIPPWVPKDRPLPPA--PLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAV 1890
P P LA P VP P PPA P+SP PP AP + P + A+
Sbjct: 755 PRVPPLLAAPPLQVP---PSPPASLPMSPLAKPPPQAPPALATPP-----------LQAL 800
Query: 1891 QEGAAELEG-GPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQT 1949
A G P+SP A P ++ P +
Sbjct: 801 PSPPASFPGQAPFSP--------SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 852
Query: 1950 EPEQREPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGR 2009
+ +R PTP PD + + L P P PP S +G
Sbjct: 853 QAPRRPPTPGPD------TSVSGPRLTLALAPGPPP-----------PPSRSPSSTLSGP 895
Query: 2010 NTSAEKELSSPISPKSLQSDTPTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPIL 2069
+ + S+ +P+ L+ +GP P P E + PA
Sbjct: 896 DLAGHSS-SATSTPEELRGYD--------SGPEGGAAASPPPDAELAACHPAA------W 940
Query: 2070 SKGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPH 2129
S+GP+PPL +P P P +G D + E E P A P P
Sbjct: 941 SRGPAPPL---AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 997
Query: 2130 PIPMGSPTLWPETEAHVSPPLDSHLG 2155
G A P + LG
Sbjct: 998 GTSGGKAAAGAGAGASSRSPKQARLG 1023
Score = 37.4 bits (85), Expect = 0.21
Identities = 65/291 (22%), Positives = 87/291 (29%), Gaps = 45/291 (15%)
Query: 996 SPPPSGPPSATHTPFHQSPVEEKSEPQDFQEADSWGDTKRTPGVGKEDAAEETVKPGPEE 1055
SPPPS P A +P PV + P ++ P + A V P P
Sbjct: 666 SPPPSPPVQAPFSPPASPPVSPSATP----------PSQAPPSLA---APPLQVPPSPPA 712
Query: 1056 GTLEKEEKVPPPRSPQAQEAPVNIDEGLTGCTIQLLPAQDKAIVFEIMEAGEP-TGPILG 1114
PPP++P AP +Q+ P+ + P P+L
Sbjct: 713 SPPMSPSATPPPQAPPPLAAP----------PLQVPPSPPASPPMSPSATPPPRVPPLLA 762
Query: 1115 AEAL------PGGLRTLPQEPGKPQKDEVLRYPDRSLSPEDAESLSVLSVPSPDTA---- 1164
A L P L P PQ L P P S + SP +
Sbjct: 763 APPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 822
Query: 1165 -NQEPTPKSPCGLTEQYLHKDRWPEVSPEDTQSLSLSEESPSKETSLDVSSKQLS----- 1218
P P++P L L P SP +L P+ VS +L+
Sbjct: 823 PLATPPPQAPPVLAAPLLQVPPSPPASP----TLQAPRRPPTPGPDTSVSGPRLTLALAP 878
Query: 1219 -PESLGTLQFGELNLGKEEMGHLMQAEDTSHHTAPMSVPEPHAATASPPTD 1268
P + G + GH A T A ASPP D
Sbjct: 879 GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 929
Score = 36.6 bits (83), Expect = 0.36
Identities = 32/119 (26%), Positives = 42/119 (35%), Gaps = 5/119 (4%)
Query: 2544 KAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQG 2603
KAG + T R P P PRP PP + + +G V R E+ G
Sbjct: 9 KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALR----VLGAAGAVGRKPLAERAGG 64
Query: 2604 RVGRRAPGKAKPASPARRLDLRGKRSPTPGKGPADRASRAPPRPRSTTSQVTPAEEKDG 2662
G P A A P R R+P + R RAPP ++ V+ G
Sbjct: 65 IGGATIPESAPRAGPTRSAG-TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG 122
Score = 32.0 bits (71), Expect = 8.8
Identities = 50/199 (25%), Positives = 66/199 (33%), Gaps = 32/199 (16%)
Query: 961 PVFSAPGHALHPGEPALGEAEERCLSPDDSTVKMASPPPSGPPSATHTPFHQSPVEEKSE 1020
P +AP + P PA SP S A+PPP PP P P S
Sbjct: 697 PSLAAPPLQVPPSPPA---------SPPMSP--SATPPPQAPPPLAAPPLQVPPSPPASP 745
Query: 1021 PQDFQEADSWGDTKRTPGVGKEDAAEETVKPGPEEGTLEKEEKVPPPRSPQAQEAPVNID 1080
P + S R P + A V P P PPP++P A P
Sbjct: 746 PM----SPSATPPPRVPPL--LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATP---- 795
Query: 1081 EGLTGCTIQLLPAQDKAIVFEI---MEAGEPTGPIL--GAEALPGGLRTLPQEPGKPQKD 1135
+Q LP+ + + A P P+ +A P L Q P P
Sbjct: 796 ------PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 849
Query: 1136 EVLRYPDRSLSPEDAESLS 1154
L+ P R +P S+S
Sbjct: 850 PTLQAPRRPPTPGPDTSVS 868
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 92.4 bits (228), Expect = 5e-18
Identities = 237/972 (24%), Positives = 320/972 (32%), Gaps = 177/972 (18%)
Query: 1773 LAESPVGLPPEEEDKLTRSPFEIISPPASPPEMVGQRVPSAPGQESPIPDPKLMPHMKNE 1832
++E P G P P ++ P PP M P P P+ + PH +
Sbjct: 154 ISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA----PPPP----PVLEALSPPHTLSS 205
Query: 1833 PTTPSWLADIPPWVPKDRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQE 1892
P+ P+ IPP P PP P PAP PP PA +P + GT + +
Sbjct: 206 PSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPA------SPHTVGTRLFPPGGVTKWK 259
Query: 1893 GAAELEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPE 1952
L G R+AE R R+ A K S P EP T P
Sbjct: 260 SDVALNG----------RQAEATRASPPRSPAEPKGSALGPNP---------EPHLTFPR 300
Query: 1953 Q-REPTPYPDERS------FQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEA 2005
+ P P P S Q A E+ G P+R P + P +
Sbjct: 301 SFKVPPPTPVRTSSIPVQEAQEAPRKEE----GATKKAPSRLPLPPSFHIRPASQVYPDR 356
Query: 2006 AAGRNTSAEKELSSPISPKSLQSDTPTFSYAALAGPTVPPRPEPGPSMEPSL--TPPAVP 2063
A + E + ++P SP+ QS + A P PP P P P + P PPA P
Sbjct: 357 APEPDCPGELKATAPASPRLGQSQSQADERAG-TPPPAPPLPPPAPPLPPPAPPLPPAAP 415
Query: 2064 PRAPILSKGPSPPL------NGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEK----- 2112
P P K PP + + P PSP+ + S D S++EK
Sbjct: 416 P-LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNEL 474
Query: 2113 -----GAREQPEKEAQSPSP---PHPIPMGSPTLWPETEAHVS-PPLDSHLGPARPSLDF 2163
G+R + + P P P PE E +S P D+ G
Sbjct: 475 AAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPG-------V 527
Query: 2164 PASAFGFSSL--QPAPPQLPSPAE---PRSAPCGSLAFSGDRALALAPGPPTRTRHDEYL 2218
P + G SSL A P L P+ P+ +P S+ + A R
Sbjct: 528 PEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEA---------RLSSAA 578
Query: 2219 EVTKAPSLDSSLPQLPSPSSPGAPLLSN------LPRPASPALSEGSSSEATTPVISSVA 2272
E PS+ SLP P P G + N L +P + L S++ T + A
Sbjct: 579 EKEAKPSI-GSLP--PKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKA 635
Query: 2273 ERFSPSLEAAEQESGELDPGMEPAAHSLWDLTP----LSPAPPASLDLALAPAPSLPGDM 2328
L A +P + P A +LW TP L PA P L P L
Sbjct: 636 -----MLGPAIPPKATPEPAIPPKA-TLWPATPPKATLGPATP--LKATSGPTTPLKATS 687
Query: 2329 GDGILPCHLECSEAATEKPSPFQVPSE-DCAANGPTETSPNPPGPAPAKAENE----EAA 2383
G I S A T + Q+ +E D G E + P++A E EA
Sbjct: 688 GPAI------ASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEAT 741
Query: 2384 ACP--------AWERGAWPEGAE---------RSSRPDTLLSPEQPVCPAGGSGGPPSSA 2426
P A+ P G E S ++ P GG+ GP
Sbjct: 742 RLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGP---G 798
Query: 2427 SPEVEAGPQGCATEPRPHRGELSPSFLNPPLPPSIDDRDLSTE---EVRLVGRGGRRRVG 2483
P P G +P P + + L P+ + +R R + GR
Sbjct: 799 EPVEVKEPPGLPAKP-PASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGA 857
Query: 2484 GPGTTGGPCPVTDETPPTSASDSGSSQSDSDVPPETEECPSITAEAALDS-------DED 2536
G + P + D + AS S S P P + EA DS ++
Sbjct: 858 ALGRSSLPGSLRDHSHQAEAS-SDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKW 916
Query: 2537 GDFLPVDKAGGVSGTHH----PRPGHD-------PPPLPQPDPRP----SPPRPDVCMAD 2581
G L D G H P P P LPQ P P SPP P +
Sbjct: 917 GPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREE 976
Query: 2582 PEGLSSESGRVERLREKEKVQGRVGRRAPG---KAKPASPARR--LDLRGKRSPTPGKGP 2636
E E E + + AP + +SP R DLR + PG P
Sbjct: 977 EE----EEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPP 1032
Query: 2637 ADRASRAPPRPR 2648
A SR P R
Sbjct: 1033 ALGFSRFPAGAR 1044
Score = 70.1 bits (170), Expect = 3e-11
Identities = 150/643 (23%), Positives = 209/643 (32%), Gaps = 125/643 (19%)
Query: 2041 PTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSPSPKESGRSH 2100
P PP P PGP + S P P +P + P PPL
Sbjct: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPL----------------------- 176
Query: 2101 WDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPS 2160
E P + +P PP + SP P T + S P P P
Sbjct: 177 -------------LLEPPPPPSMAPPPPPVLEALSP---PHTLSSPSIPTPPDFIPPAPP 220
Query: 2161 LDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEV 2220
L F L P PP +P+PA P A ++ G R PG T+ + D L
Sbjct: 221 LAF---------LAPPPPPVPAPAPPAPASPHTV---GTR--LFPPGGVTKWKSDVALNG 266
Query: 2221 TKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFSPSLE 2280
+A + +S P+ SP+ P L P P P L+ S + P + V P E
Sbjct: 267 RQAEATRASPPR--SPAEPKGSALG--PNP-EPHLTFPRSFKVPPP--TPVRTSSIPVQE 319
Query: 2281 AAEQESGELDPGMEPAAHSLWDLTPLSPAPPAS-LDLALAPAPSLPGDMGDGILPCHLEC 2339
A QE+ + G A S L P PAS + AP P PG+ L+
Sbjct: 320 A--QEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGE---------LKA 368
Query: 2340 SEAATEKPSPFQVPSEDCAAN---GPTETSPNPPGPAPAKAENEEAAACPAWERGAWPEG 2396
+ A+ + Q +++ A P P PP P PA A P ++ A P
Sbjct: 369 TAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPA 428
Query: 2397 ----AERSSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSF 2452
+SS P P P S P P ++ R EL+
Sbjct: 429 GFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDP----------SQMEKLRNELAAYL 478
Query: 2453 LNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGP----GTTGGPCPVTDETPPTSASDSGS 2508
+DR LS V + GP T P D P G
Sbjct: 479 CG----SRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGG 534
Query: 2509 SQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDP 2568
S ETE PS+T + +D P + R +P
Sbjct: 535 SSL-----TETEAAPSLTLPSVDYIPQDS---PTPSVRQIRNELEARLSSAAEKEAKPSI 586
Query: 2569 RPSPPRPDVCMADPEGLSSESGRV-ERLREKEKVQGRVGRRAPGKAKPASPARRLDLRG- 2626
PP+P + E GR+ E + +K+ V + P ++ P L +
Sbjct: 587 GSLPPKPRL----------EGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAM 636
Query: 2627 -------KRSPTPGKGPADRASRAPPRPRSTTSQVTPAEEKDG 2662
K +P P P A P P++T TP + G
Sbjct: 637 LGPAIPPKATPEPAIPPKATLWPATP-PKATLGPATPLKATSG 678
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 92.4 bits (228), Expect = 5e-18
Identities = 237/972 (24%), Positives = 320/972 (32%), Gaps = 177/972 (18%)
Query: 1773 LAESPVGLPPEEEDKLTRSPFEIISPPASPPEMVGQRVPSAPGQESPIPDPKLMPHMKNE 1832
++E P G P P ++ P PP M P P P+ + PH +
Sbjct: 154 ISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA----PPPP----PVLEALSPPHTLSS 205
Query: 1833 PTTPSWLADIPPWVPKDRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQE 1892
P+ P+ IPP P PP P PAP PP PA +P + GT + +
Sbjct: 206 PSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPA------SPHTVGTRLFPPGGVTKWK 259
Query: 1893 GAAELEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPE 1952
L G R+AE R R+ A K S P EP T P
Sbjct: 260 SDVALNG----------RQAEATRASPPRSPAEPKGSALGPNP---------EPHLTFPR 300
Query: 1953 Q-REPTPYPDERS------FQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEA 2005
+ P P P S Q A E+ G P+R P + P +
Sbjct: 301 SFKVPPPTPVRTSSIPVQEAQEAPRKEE----GATKKAPSRLPLPPSFHIRPASQVYPDR 356
Query: 2006 AAGRNTSAEKELSSPISPKSLQSDTPTFSYAALAGPTVPPRPEPGPSMEPSL--TPPAVP 2063
A + E + ++P SP+ QS + A P PP P P P + P PPA P
Sbjct: 357 APEPDCPGELKATAPASPRLGQSQSQADERAG-TPPPAPPLPPPAPPLPPPAPPLPPAAP 415
Query: 2064 PRAPILSKGPSPPL------NGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEK----- 2112
P P K PP + + P PSP+ + S D S++EK
Sbjct: 416 P-LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNEL 474
Query: 2113 -----GAREQPEKEAQSPSP---PHPIPMGSPTLWPETEAHVS-PPLDSHLGPARPSLDF 2163
G+R + + P P P PE E +S P D+ G
Sbjct: 475 AAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPG-------V 527
Query: 2164 PASAFGFSSL--QPAPPQLPSPAE---PRSAPCGSLAFSGDRALALAPGPPTRTRHDEYL 2218
P + G SSL A P L P+ P+ +P S+ + A R
Sbjct: 528 PEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEA---------RLSSAA 578
Query: 2219 EVTKAPSLDSSLPQLPSPSSPGAPLLSN------LPRPASPALSEGSSSEATTPVISSVA 2272
E PS+ SLP P P G + N L +P + L S++ T + A
Sbjct: 579 EKEAKPSI-GSLP--PKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKA 635
Query: 2273 ERFSPSLEAAEQESGELDPGMEPAAHSLWDLTP----LSPAPPASLDLALAPAPSLPGDM 2328
L A +P + P A +LW TP L PA P L P L
Sbjct: 636 -----MLGPAIPPKATPEPAIPPKA-TLWPATPPKATLGPATP--LKATSGPTTPLKATS 687
Query: 2329 GDGILPCHLECSEAATEKPSPFQVPSE-DCAANGPTETSPNPPGPAPAKAENE----EAA 2383
G I S A T + Q+ +E D G E + P++A E EA
Sbjct: 688 GPAI------ASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEAT 741
Query: 2384 ACP--------AWERGAWPEGAE---------RSSRPDTLLSPEQPVCPAGGSGGPPSSA 2426
P A+ P G E S ++ P GG+ GP
Sbjct: 742 RLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGP---G 798
Query: 2427 SPEVEAGPQGCATEPRPHRGELSPSFLNPPLPPSIDDRDLSTE---EVRLVGRGGRRRVG 2483
P P G +P P + + L P+ + +R R + GR
Sbjct: 799 EPVEVKEPPGLPAKP-PASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGA 857
Query: 2484 GPGTTGGPCPVTDETPPTSASDSGSSQSDSDVPPETEECPSITAEAALDS-------DED 2536
G + P + D + AS S S P P + EA DS ++
Sbjct: 858 ALGRSSLPGSLRDHSHQAEAS-SDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKW 916
Query: 2537 GDFLPVDKAGGVSGTHH----PRPGHD-------PPPLPQPDPRP----SPPRPDVCMAD 2581
G L D G H P P P LPQ P P SPP P +
Sbjct: 917 GPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREE 976
Query: 2582 PEGLSSESGRVERLREKEKVQGRVGRRAPG---KAKPASPARR--LDLRGKRSPTPGKGP 2636
E E E + + AP + +SP R DLR + PG P
Sbjct: 977 EE----EEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPP 1032
Query: 2637 ADRASRAPPRPR 2648
A SR P R
Sbjct: 1033 ALGFSRFPAGAR 1044
Score = 70.1 bits (170), Expect = 3e-11
Identities = 150/643 (23%), Positives = 209/643 (32%), Gaps = 125/643 (19%)
Query: 2041 PTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSPSPKESGRSH 2100
P PP P PGP + S P P +P + P PPL
Sbjct: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPL----------------------- 176
Query: 2101 WDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPS 2160
E P + +P PP + SP P T + S P P P
Sbjct: 177 -------------LLEPPPPPSMAPPPPPVLEALSP---PHTLSSPSIPTPPDFIPPAPP 220
Query: 2161 LDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEV 2220
L F L P PP +P+PA P A ++ G R PG T+ + D L
Sbjct: 221 LAF---------LAPPPPPVPAPAPPAPASPHTV---GTR--LFPPGGVTKWKSDVALNG 266
Query: 2221 TKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFSPSLE 2280
+A + +S P+ SP+ P L P P P L+ S + P + V P E
Sbjct: 267 RQAEATRASPPR--SPAEPKGSALG--PNP-EPHLTFPRSFKVPPP--TPVRTSSIPVQE 319
Query: 2281 AAEQESGELDPGMEPAAHSLWDLTPLSPAPPAS-LDLALAPAPSLPGDMGDGILPCHLEC 2339
A QE+ + G A S L P PAS + AP P PG+ L+
Sbjct: 320 A--QEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGE---------LKA 368
Query: 2340 SEAATEKPSPFQVPSEDCAAN---GPTETSPNPPGPAPAKAENEEAAACPAWERGAWPEG 2396
+ A+ + Q +++ A P P PP P PA A P ++ A P
Sbjct: 369 TAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPA 428
Query: 2397 ----AERSSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSF 2452
+SS P P P S P P ++ R EL+
Sbjct: 429 GFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDP----------SQMEKLRNELAAYL 478
Query: 2453 LNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGP----GTTGGPCPVTDETPPTSASDSGS 2508
+DR LS V + GP T P D P G
Sbjct: 479 CG----SRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGG 534
Query: 2509 SQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDP 2568
S ETE PS+T + +D P + R +P
Sbjct: 535 SSL-----TETEAAPSLTLPSVDYIPQDS---PTPSVRQIRNELEARLSSAAEKEAKPSI 586
Query: 2569 RPSPPRPDVCMADPEGLSSESGRV-ERLREKEKVQGRVGRRAPGKAKPASPARRLDLRG- 2626
PP+P + E GR+ E + +K+ V + P ++ P L +
Sbjct: 587 GSLPPKPRL----------EGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAM 636
Query: 2627 -------KRSPTPGKGPADRASRAPPRPRSTTSQVTPAEEKDG 2662
K +P P P A P P++T TP + G
Sbjct: 637 LGPAIPPKATPEPAIPPKATLWPATP-PKATLGPATPLKATSG 678
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens]
Length = 1188
Score = 92.4 bits (228), Expect = 5e-18
Identities = 237/972 (24%), Positives = 320/972 (32%), Gaps = 177/972 (18%)
Query: 1773 LAESPVGLPPEEEDKLTRSPFEIISPPASPPEMVGQRVPSAPGQESPIPDPKLMPHMKNE 1832
++E P G P P ++ P PP M P P P+ + PH +
Sbjct: 154 ISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA----PPPP----PVLEALSPPHTLSS 205
Query: 1833 PTTPSWLADIPPWVPKDRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQE 1892
P+ P+ IPP P PP P PAP PP PA +P + GT + +
Sbjct: 206 PSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPA------SPHTVGTRLFPPGGVTKWK 259
Query: 1893 GAAELEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPE 1952
L G R+AE R R+ A K S P EP T P
Sbjct: 260 SDVALNG----------RQAEATRASPPRSPAEPKGSALGPNP---------EPHLTFPR 300
Query: 1953 Q-REPTPYPDERS------FQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEA 2005
+ P P P S Q A E+ G P+R P + P +
Sbjct: 301 SFKVPPPTPVRTSSIPVQEAQEAPRKEE----GATKKAPSRLPLPPSFHIRPASQVYPDR 356
Query: 2006 AAGRNTSAEKELSSPISPKSLQSDTPTFSYAALAGPTVPPRPEPGPSMEPSL--TPPAVP 2063
A + E + ++P SP+ QS + A P PP P P P + P PPA P
Sbjct: 357 APEPDCPGELKATAPASPRLGQSQSQADERAG-TPPPAPPLPPPAPPLPPPAPPLPPAAP 415
Query: 2064 PRAPILSKGPSPPL------NGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEK----- 2112
P P K PP + + P PSP+ + S D S++EK
Sbjct: 416 P-LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNEL 474
Query: 2113 -----GAREQPEKEAQSPSP---PHPIPMGSPTLWPETEAHVS-PPLDSHLGPARPSLDF 2163
G+R + + P P P PE E +S P D+ G
Sbjct: 475 AAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPG-------V 527
Query: 2164 PASAFGFSSL--QPAPPQLPSPAE---PRSAPCGSLAFSGDRALALAPGPPTRTRHDEYL 2218
P + G SSL A P L P+ P+ +P S+ + A R
Sbjct: 528 PEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEA---------RLSSAA 578
Query: 2219 EVTKAPSLDSSLPQLPSPSSPGAPLLSN------LPRPASPALSEGSSSEATTPVISSVA 2272
E PS+ SLP P P G + N L +P + L S++ T + A
Sbjct: 579 EKEAKPSI-GSLP--PKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKA 635
Query: 2273 ERFSPSLEAAEQESGELDPGMEPAAHSLWDLTP----LSPAPPASLDLALAPAPSLPGDM 2328
L A +P + P A +LW TP L PA P L P L
Sbjct: 636 -----MLGPAIPPKATPEPAIPPKA-TLWPATPPKATLGPATP--LKATSGPTTPLKATS 687
Query: 2329 GDGILPCHLECSEAATEKPSPFQVPSE-DCAANGPTETSPNPPGPAPAKAENE----EAA 2383
G I S A T + Q+ +E D G E + P++A E EA
Sbjct: 688 GPAI------ASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEAT 741
Query: 2384 ACP--------AWERGAWPEGAE---------RSSRPDTLLSPEQPVCPAGGSGGPPSSA 2426
P A+ P G E S ++ P GG+ GP
Sbjct: 742 RLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGP---G 798
Query: 2427 SPEVEAGPQGCATEPRPHRGELSPSFLNPPLPPSIDDRDLSTE---EVRLVGRGGRRRVG 2483
P P G +P P + + L P+ + +R R + GR
Sbjct: 799 EPVEVKEPPGLPAKP-PASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGA 857
Query: 2484 GPGTTGGPCPVTDETPPTSASDSGSSQSDSDVPPETEECPSITAEAALDS-------DED 2536
G + P + D + AS S S P P + EA DS ++
Sbjct: 858 ALGRSSLPGSLRDHSHQAEAS-SDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKW 916
Query: 2537 GDFLPVDKAGGVSGTHH----PRPGHD-------PPPLPQPDPRP----SPPRPDVCMAD 2581
G L D G H P P P LPQ P P SPP P +
Sbjct: 917 GPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREE 976
Query: 2582 PEGLSSESGRVERLREKEKVQGRVGRRAPG---KAKPASPARR--LDLRGKRSPTPGKGP 2636
E E E + + AP + +SP R DLR + PG P
Sbjct: 977 EE----EEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPP 1032
Query: 2637 ADRASRAPPRPR 2648
A SR P R
Sbjct: 1033 ALGFSRFPAGAR 1044
Score = 70.1 bits (170), Expect = 3e-11
Identities = 150/643 (23%), Positives = 209/643 (32%), Gaps = 125/643 (19%)
Query: 2041 PTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSPSPKESGRSH 2100
P PP P PGP + S P P +P + P PPL
Sbjct: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPL----------------------- 176
Query: 2101 WDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPS 2160
E P + +P PP + SP P T + S P P P
Sbjct: 177 -------------LLEPPPPPSMAPPPPPVLEALSP---PHTLSSPSIPTPPDFIPPAPP 220
Query: 2161 LDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEV 2220
L F L P PP +P+PA P A ++ G R PG T+ + D L
Sbjct: 221 LAF---------LAPPPPPVPAPAPPAPASPHTV---GTR--LFPPGGVTKWKSDVALNG 266
Query: 2221 TKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFSPSLE 2280
+A + +S P+ SP+ P L P P P L+ S + P + V P E
Sbjct: 267 RQAEATRASPPR--SPAEPKGSALG--PNP-EPHLTFPRSFKVPPP--TPVRTSSIPVQE 319
Query: 2281 AAEQESGELDPGMEPAAHSLWDLTPLSPAPPAS-LDLALAPAPSLPGDMGDGILPCHLEC 2339
A QE+ + G A S L P PAS + AP P PG+ L+
Sbjct: 320 A--QEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGE---------LKA 368
Query: 2340 SEAATEKPSPFQVPSEDCAAN---GPTETSPNPPGPAPAKAENEEAAACPAWERGAWPEG 2396
+ A+ + Q +++ A P P PP P PA A P ++ A P
Sbjct: 369 TAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPA 428
Query: 2397 ----AERSSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSF 2452
+SS P P P S P P ++ R EL+
Sbjct: 429 GFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDP----------SQMEKLRNELAAYL 478
Query: 2453 LNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGP----GTTGGPCPVTDETPPTSASDSGS 2508
+DR LS V + GP T P D P G
Sbjct: 479 CG----SRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGG 534
Query: 2509 SQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDP 2568
S ETE PS+T + +D P + R +P
Sbjct: 535 SSL-----TETEAAPSLTLPSVDYIPQDS---PTPSVRQIRNELEARLSSAAEKEAKPSI 586
Query: 2569 RPSPPRPDVCMADPEGLSSESGRV-ERLREKEKVQGRVGRRAPGKAKPASPARRLDLRG- 2626
PP+P + E GR+ E + +K+ V + P ++ P L +
Sbjct: 587 GSLPPKPRL----------EGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAM 636
Query: 2627 -------KRSPTPGKGPADRASRAPPRPRSTTSQVTPAEEKDG 2662
K +P P P A P P++T TP + G
Sbjct: 637 LGPAIPPKATPEPAIPPKATLWPATP-PKATLGPATPLKATSG 678
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 91.7 bits (226), Expect = 9e-18
Identities = 95/426 (22%), Positives = 197/426 (46%), Gaps = 60/426 (14%)
Query: 1309 ITSPDEHILTPDSSFSKSPESLP--GPALED-----------IAIKWE------DKVPGL 1349
IT D + + F++ E+L G L +A KWE +K+
Sbjct: 1623 ITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKK 1682
Query: 1350 KDRTSEQKKEPEPKDEVLQQKDKTLE--HKEVVEPKDTAIYQKDEALHVKNEAVKQQDKA 1407
+ +E K K E L Q+++ L+ KE+ + + + +E + E +++ K
Sbjct: 1683 GGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKL 1742
Query: 1408 LEQKGRDLEQKDTALEQKDKALEPKDKD-------LEEKDKALEQKDKIPEEKDKALEQK 1460
+E+K + E+++ Q++K E + K ++EK+K + K+K+PEE+++ ++
Sbjct: 1743 VEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKR 1802
Query: 1461 DTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKD 1520
+ +E+K K + +++ + + + + K + ++K+ A ++K + E ++ +A+ K+
Sbjct: 1803 EQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQE----KEKLAQRKE 1858
Query: 1521 RDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQE 1580
L ++ K Q + K+K LG ++ L Q E TQE
Sbjct: 1859 NLLYNKERLTHSKKQLVQVKNK---------------LGMFNKILAQ-----VEEKLTQE 1898
Query: 1581 QESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKY 1640
+E++++ K K E+K + ++ +K E L ++ L LE+++VQ G+ R + E
Sbjct: 1899 KETVIK--KKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQ-GKKRLRGE-- 1953
Query: 1641 WRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQDTYWREL 1700
D+ +E + + + A E+ L E S + R R+ +EQ+ + R+L
Sbjct: 1954 ---LDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKL 2010
Query: 1701 SCERKV 1706
S E K+
Sbjct: 2011 SLEEKI 2016
Score = 80.1 bits (196), Expect = 3e-14
Identities = 114/529 (21%), Positives = 229/529 (43%), Gaps = 64/529 (12%)
Query: 1313 DEHILTPDSSFSKSPESLPGPALEDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDK 1372
+ +L D + P +++ AI+ ED + G+ K+ ++E Q+K +
Sbjct: 1297 ESKVLLEDLDWDVVPPEKKPIFIQEGAIR-EDMIQGVTQEVIRHKEVMPREEEQAQKKAR 1355
Query: 1373 T---LEHKEVVEPKDT-AIYQKDEALHVKNEAVKQQDKALEQK----GRDLEQKDTALEQ 1424
LE +V+ K I+ + + + E K+++K QK GR QK+ + +
Sbjct: 1356 DMLGLEETQVILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAVQKERKVGK 1415
Query: 1425 KDKALEPKDKDL-EEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDL----- 1478
+ + +++D+ EE ++ ++K+ +++ K + + T Q K + K +
Sbjct: 1416 IKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETR 1475
Query: 1479 --------EQKDRVLEQKEKI--------PEEKDKALDQKVRSVEHKAPEDTVAEMKDRD 1522
E + R+L+++EK+ PEE+ D+K++ E K + + K ++
Sbjct: 1476 KSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKE 1535
Query: 1523 LEQTDKAP-----EQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQ 1577
+ D+ E + +E++ +V+E++ E+ WA + A + +A EE
Sbjct: 1536 QQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKL 1595
Query: 1578 TQEQESLVQEDKTRKPKMLEEKSPEK-VKAMEEKLEALLEKTKALGLEESLVQEGR--AR 1634
QE+E L QE+ R+ E K + VK ++ E + K EE+L Q G ++
Sbjct: 1596 AQEEEKLAQEE--RQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQ 1653
Query: 1635 EQEEKYWRGQDVVQEWQETSPTREEPA---GEQKE----LAPAWEDTSPEQDNRYWRGRE 1687
E E+ + + + ++W++ + E+ A G+ E LA E+ + N W+ +E
Sbjct: 1654 EAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKE 1713
Query: 1688 DVALEQDTYWRELSCERKVWFPHELDGQGARPHYTEERESTFLDEGPDDEQEVPLREHAT 1747
L Q+ E E W EL+ + + EE++ +E Q L E T
Sbjct: 1714 ---LAQELEELEWDMEELSWKEEELNQEEGK--LVEEKKKLAEEEEALAWQREKLSEEET 1768
Query: 1748 RSPWASDFKDFQESSPQKGLEVERWLAESPVGLPPEEEDKLTRSPFEII 1796
+ + ++ + LA+ + PEEE++L R ++I
Sbjct: 1769 KLAQEEELL----------IQEKEKLAQHKEKM-PEEEERLGRKREQLI 1806
Score = 73.9 bits (180), Expect = 2e-12
Identities = 74/319 (23%), Positives = 145/319 (45%), Gaps = 47/319 (14%)
Query: 1358 KEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQ 1417
KEP +++L+ K + + ++ + + AL VK + + L+ K D +
Sbjct: 2068 KEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSE 2127
Query: 1418 KDTALEQKDKALEPKDKDLEEK-DKALEQKDKIPEEKDKAL---------EQKDTALEQK 1467
K + L + +K L K + L K + + +++K+ EE+ K ++++ +E++
Sbjct: 2128 KRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEE 2187
Query: 1468 D----------------KALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQ--KVRSV--- 1506
+ + +PK+K Q D V E +E EE + LD+ K S+
Sbjct: 2188 EVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEV-ESEEHFSEEMESLLDELEKQESLSSE 2246
Query: 1507 --EHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEA 1564
E + E+ E + R+ E+ K E+ + Q +K++ EKK + E+K + +K+E
Sbjct: 2247 EEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEE-EEKKKKKKEKKKEEVQEKEEV 2305
Query: 1565 LEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLE 1624
E+ + + E +E ESL E++ + LEE+ ++ + +L+K K L+
Sbjct: 2306 FEEKEEIMSE----EETESLSDEEEEEESCSLEEE--------VDREKEILKKEKQFKLQ 2353
Query: 1625 ESLVQEGRAREQEEKYWRG 1643
E + R RE+ RG
Sbjct: 2354 EQRRKSLRGRERVLSILRG 2372
Score = 67.4 bits (163), Expect = 2e-10
Identities = 94/429 (21%), Positives = 183/429 (42%), Gaps = 42/429 (9%)
Query: 298 DLASGAVPTNLKPSKIKQR----ADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELA 353
D+A NL+ ++ + + KE+L S+ K +V +E E + L
Sbjct: 1955 DIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQE-LFERKLSLE 2013
Query: 354 KELAKTEKK--AKESSE--KPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKI 409
+++ E + A E SE K + + +R+ + L RKLIK + E +
Sbjct: 2014 EKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKR-------ESL 2066
Query: 410 SKLEEKKDKEKKEIKK----ERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLK 465
SK K +K K ++K ERK +++ + K+ +E+R + I + D
Sbjct: 2067 SKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFS 2126
Query: 466 PFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVL 525
E+ K K R ++ R + ++E +E ++ A+K H E++L
Sbjct: 2127 EKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARK----------HSEVIL 2176
Query: 526 SSPEDLTQDFEEMKREERALLAEQRDTGLGDKP---FPLDTAEEGPPSTAIQGTPPSVPG 582
E+ + EE+ + ++++ GDKP F E + +
Sbjct: 2177 DDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDE 2236
Query: 583 LGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEARE 642
L ++E + E+E E EE+ ++ + E +EE++ E++ ++E E + + ++
Sbjct: 2237 LEKQESLSSEEEEERE-EEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKK 2295
Query: 643 ESEPEVKEDVIEKAE---LEEMEEVHPSDEEEEDATKAEGFYQKH-----MQEPLKVTPR 694
+ E + KE+V E+ E EE E +EEEE++ E + ++ K+ +
Sbjct: 2296 KEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQ 2355
Query: 695 SREAFGGRE 703
R++ GRE
Sbjct: 2356 RRKSLRGRE 2364
Score = 67.4 bits (163), Expect = 2e-10
Identities = 76/344 (22%), Positives = 158/344 (45%), Gaps = 15/344 (4%)
Query: 1348 GLKDRTSEQKKEPEPKDEVLQQK----DKTLEHKEVVEPKDTAIYQKDEALHVKNEAV-K 1402
G TS Q+K + + E+ ++K +K L H++ + + + K + + + +
Sbjct: 1987 GETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFV 2046
Query: 1403 QQDKALEQKGRDLEQKDTALEQK----DKALEPKDKDLEEKDKALEQKDKIPEEKDKALE 1458
Q + L + R L +K +L ++ +K L+ K ++ K +++ K+ + K +AL
Sbjct: 2047 QGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMK-RALF 2105
Query: 1459 QKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEM 1518
K+ L + L+ K+ D +K L + EK K + L K+R + +K + T E
Sbjct: 2106 VKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEES 2165
Query: 1519 KDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKD-EALEQNIQALE-ENH 1576
K +++ E+++ + K + ++K G K E + +E E H
Sbjct: 2166 KLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEH 2225
Query: 1577 QTQEQESLVQE---DKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRA 1633
++E ESL+ E ++ + EE+ E+ + EE E E+ + EE V++
Sbjct: 2226 FSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEE 2285
Query: 1634 REQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPE 1677
++++K + ++ VQE +E +EE E++ + + E+ E
Sbjct: 2286 EKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEE 2329
Score = 65.5 bits (158), Expect = 7e-10
Identities = 90/467 (19%), Positives = 201/467 (43%), Gaps = 76/467 (16%)
Query: 1336 EDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVL-QQKDKTLEHKEVVEPK-----DTAIYQ 1389
++ IK ++K+ + + + + K E L Q+K K K +V+ K + I +
Sbjct: 1899 KETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAK 1958
Query: 1390 KDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKI 1449
+++AL+++ + + ++ L + L + +T + + + +++L E+ +LE+K +
Sbjct: 1959 EEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILL 2018
Query: 1450 PEEKDKALEQKDTALEQKD-----------------------KALEPKDKDLEQKDRVLE 1486
E++ A+E+ + A + + K E K+ + +++L+
Sbjct: 2019 HEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILK 2078
Query: 1487 QKEKIPEEKDKALDQKVRSVEHK-----APEDTVAEMKDRDLEQTDKAPEQKHQAQEQKD 1541
+K+ ++ K ++++ + K E D+++ D + ++ +++K
Sbjct: 2079 ALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKK 2138
Query: 1542 KVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQ----TQEQESLVQED------KTR 1591
+K + L K + K+E + + L H E+E ++E+ K R
Sbjct: 2139 LA--RKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRR 2196
Query: 1592 KPKMLEEKSPEKVKA--------------MEEKLEALLEKTKALGLEESLVQEGRAREQE 1637
K E K +K K E++E+LL++ L +ESL E +E
Sbjct: 2197 WRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDE---LEKQESLSSEEEEEREE 2253
Query: 1638 EKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQDTYW 1697
E+ ++V +E +E +EE GE+K++ E+ ++ + +E+V +++ +
Sbjct: 2254 EEEREEEEVREEEEE---RKEEEEGEEKQVEKEEEEKKKKKKE---KKKEEVQEKEEVF- 2306
Query: 1698 RELSCERKVWFPHELDGQGARPHYTEERESTFLDEGPDDEQEVPLRE 1744
E K E + + EE ES L+E D E+E+ +E
Sbjct: 2307 -----EEKEEIMSEEETESLSDE-EEEEESCSLEEEVDREKEILKKE 2347
Score = 58.2 bits (139), Expect = 1e-07
Identities = 64/281 (22%), Positives = 131/281 (46%), Gaps = 36/281 (12%)
Query: 1336 EDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALH 1395
E+ I+ E+ +P LK R ++K E K +PK+ Q DE
Sbjct: 2180 EEGGIEEEEVIPFLKRRWRKRK-----------------EAKRGDKPKEKFSSQVDEV-- 2220
Query: 1396 VKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDK 1455
E+ + + +E +LE++++ ++++ E +++ EE+ + E++ K EE ++
Sbjct: 2221 ---ESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEE 2277
Query: 1456 ALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTV 1515
+K+ E+K K E K +++++K+ V E+KE+I E++ + + E + ++
Sbjct: 2278 KQVEKEEE-EKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEE---TESLSDEEEEEESCSL 2333
Query: 1516 AEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEEN 1575
E DR+ E K E++ + QEQ+ K +++ L K A+ + L+
Sbjct: 2334 EEEVDREKEILKK--EKQFKLQEQRRKSLRGRERVLSILRGVPHGKGRAIRLGV--LKSP 2389
Query: 1576 HQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKLEALLE 1616
+ +L ++KT P PEK + E+K ++E
Sbjct: 2390 LKKLMSTALEMKEKTPVP------VPEKQISWEDKKATVVE 2424
Score = 57.8 bits (138), Expect = 2e-07
Identities = 88/329 (26%), Positives = 143/329 (43%), Gaps = 66/329 (20%)
Query: 332 SKLAKREEVV-----EEGAKEARSELAKELAKTEKKAKESS--EKPPEKPAKPERVKTES 384
SKLA++ V EEG E E+ L + +K KE+ +KP EK + + + ES
Sbjct: 2165 SKLARKHSEVILDDEEEGGIE-EEEVIPFLKRRWRKRKEAKRGDKPKEKFSS-QVDEVES 2222
Query: 385 SEALKAEKRKLIKDKVGKKHLK-EKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDA 443
E E L+ + ++ L E+ + EE++++E++E+++E +E +K+E EEK+
Sbjct: 2223 EEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEE-RKEEEEGEEKQVE 2281
Query: 444 KKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQ 503
K+EE++K K E KK EV+ ++ ++E+ SE +
Sbjct: 2282 KEEEEKKKKKKEKKK----------EEVQ--------------EKEEVFEEKEEIMSEEE 2317
Query: 504 TPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDT 563
T E S E++ ++ E +K+E++ L EQR L + L
Sbjct: 2318 TESLSD--------EEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRERVLSI 2369
Query: 564 AEEGP--PSTAIQ-GTPPS-VPGLGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAETEEE 619
P AI+ G S + L MKEK VP VPE+Q S
Sbjct: 2370 LRGVPHGKGRAIRLGVLKSPLKKLMSTALEMKEKTPVP-VPEKQIS-------------- 2414
Query: 620 KDTWEEKKQREAERLPDRTEAREESEPEV 648
WE+KK E +P + + E EV
Sbjct: 2415 ---WEDKKATVVE-IPRKFLGTMDKEREV 2439
Score = 56.6 bits (135), Expect = 3e-07
Identities = 50/226 (22%), Positives = 109/226 (48%), Gaps = 24/226 (10%)
Query: 1320 DSSFSKSPESLPGPALEDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLEHKEV 1379
+ FS+ ESL L+++ +K L E+++E E ++E + +++ E KE
Sbjct: 2223 EEHFSEEMESL----LDEL-----EKQESLSSEEEEEREEEEEREEE-EVREEEEERKEE 2272
Query: 1380 VEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEK 1439
E ++ + +++E +++ K E+K ++++K+ E+K++ + ++ +
Sbjct: 2273 EEGEEKQVEKEEE---------EKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSD 2323
Query: 1440 DKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKAL 1499
++ E+ + EE D+ E++ E++ K E + K L ++RVL +P K +A+
Sbjct: 2324 EEEEEESCSLEEEVDR--EKEILKKEKQFKLQEQRRKSLRGRERVLSILRGVPHGKGRAI 2381
Query: 1500 DQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSE 1545
V K T EMK++ PE++ +++K V E
Sbjct: 2382 RLGVLKSPLKKLMSTALEMKEK---TPVPVPEKQISWEDKKATVVE 2424
Score = 52.4 bits (124), Expect = 6e-06
Identities = 45/180 (25%), Positives = 85/180 (47%), Gaps = 16/180 (8%)
Query: 279 GLEKLRHLDFLRYPVATQKDLASGAVPTNLKPSKIKQRADSKESLKATTKTAVSKLAKRE 338
G+E+ + FL+ +K+ G P S++ + +S+E ++ + +L K+E
Sbjct: 2183 GIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDE-VESEEHFSEEMESLLDELEKQE 2241
Query: 339 EVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKD 398
+ E +E E +E E++ +E E ER + E E + EK + K
Sbjct: 2242 SLSSEEEEEREEEEERE----EEEVREEEE---------ERKEEEEGEEKQVEKEEEEKK 2288
Query: 399 KVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKK 458
K K+ KE++ + EE +++++ + +E E DE +EE++ EE+ K LKK
Sbjct: 2289 KKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDE--EEEEESCSLEEEVDREKEILKK 2346
Score = 51.2 bits (121), Expect = 1e-05
Identities = 96/470 (20%), Positives = 197/470 (41%), Gaps = 51/470 (10%)
Query: 333 KLA-KREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAE 391
KLA KRE + + ++++ K + K++ + EK A+ + + E L
Sbjct: 1811 KLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHS 1870
Query: 392 KRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKD 451
K++L++ K + ++++EEK +EK+ + K++++L + E + + +D+ +++ K
Sbjct: 1871 KKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKL 1930
Query: 452 TKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGT 511
+ ++K + + +R L AK + ++ R + L +T KG
Sbjct: 1931 AQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKET--LSKGE 1988
Query: 512 VPLPTISGHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAE-EGPPS 570
P S R++ E + ++ EE+ LL E R + + E
Sbjct: 1989 T--PETSRQRKMTQVEQELFER---KLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQR 2043
Query: 571 TAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWEEKKQRE 630
+QG ++K++E + + P + + L +E K T EE K +
Sbjct: 2044 IFVQGQRKLAKA---SRKLIKKRESLSKEPAKLNKILKALQK-LTRDERKLTQEEIKMTK 2099
Query: 631 AER---LPDRTEAREESEPEVKE-DVIEK-AELEEME------------EVHPSDEEEED 673
+R + +R + E+S+ ++KE D EK +EL + E ++ +EE
Sbjct: 2100 MKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEK 2159
Query: 674 ATKAEG-FYQKHMQ-----------EPLKVTPRSREAFGGRELGLQGKAPEKETSLFLSS 721
T+ E +KH + E +V P + + R+ +G P+++ S +
Sbjct: 2160 MTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDE 2219
Query: 722 LTTPAGATEHVSYIQDETIPGYS---------ETEQTISDEEIHDEPEER 762
+ + +E + + DE S E E+ +EE+ +E EER
Sbjct: 2220 VESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEER 2269
Score = 49.7 bits (117), Expect = 4e-05
Identities = 104/489 (21%), Positives = 182/489 (37%), Gaps = 89/489 (18%)
Query: 297 KDLASGAVPTNLKPSKIKQRADSKESLKATTKTAV--SKLAKREEVVEEGAKEARSEL-- 352
+DL VP KP I++ A ++ ++ T+ + ++ REE E+ K+AR L
Sbjct: 1303 EDLDWDVVPPEKKPIFIQEGAIREDMIQGVTQEVIRHKEVMPREE--EQAQKKARDMLGL 1360
Query: 353 -----------------------AKELA-KTEKKAKESSEKPPEKPAKPERVKTESSEAL 388
KE++ K EKK + S K K + ER + +
Sbjct: 1361 EETQVILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKREM 1420
Query: 389 KAEKRKLIKDKVGKKHLKEKISKLEEK-----KDKEKKEIKKERKELKKDEGRKEEKKDA 443
E+R + ++ L+EK+ K E K + ++ KK E K+ G + A
Sbjct: 1421 TKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKA 1480
Query: 444 KKEEKRKDTKPELKKISKPDLKPFTPEVR-------------KTLYKAKVPGRVKIDR-- 488
KEE K E +K+ + K +PE K +++ + + K +
Sbjct: 1481 WKEEWEKRLLQEEEKLHQAGEK-LSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYK 1539
Query: 489 -SRAIRGEKELSSEPQTPPAQKGTVPLPTISGHR------------ELVLSSPEDLTQDF 535
+ E+E+S E + Q H+ + L Q+
Sbjct: 1540 DEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEE 1599
Query: 536 EEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQ------EEHV 589
E++ +EER L E+R D E ++ G+ E+
Sbjct: 1600 EKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLA 1659
Query: 590 MKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVK 649
K K+L + + +++ G + E K+ +K E LP R + + E E+
Sbjct: 1660 QKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQK----VEELPQREQNLDWQEKELA 1715
Query: 650 EDVIEKAELEEME-EVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFGGRELGLQG 708
+ ELEE+E ++ +EE+ + EG K ++E K+ RE
Sbjct: 1716 Q------ELEELEWDMEELSWKEEELNQEEG---KLVEEKKKLAEEEEALAWQRE----- 1761
Query: 709 KAPEKETSL 717
K E+ET L
Sbjct: 1762 KLSEEETKL 1770
Score = 49.7 bits (117), Expect = 4e-05
Identities = 95/419 (22%), Positives = 194/419 (46%), Gaps = 36/419 (8%)
Query: 308 LKPSKIKQRADSKESLKATTKTAVSK--LAKREEVVEEGAKEARSELAKELAKTEKKAKE 365
L + +K D +E +A K A + LA+R E + + A E ++ K+LAK +K
Sbjct: 1616 LAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEA-EKLAQKRKKLAKKWEKVAR 1674
Query: 366 SSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKK 425
EK +K K VK ++ ++ ++ +K L +++ +LE + +E+
Sbjct: 1675 EEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEW----DMEELSW 1730
Query: 426 ERKELKKDEGR--KEEKKDAKKEE----KRKDTKPELKKISKPDLKPFTPEVRKTLYKAK 479
+ +EL ++EG+ +E+KK A++EE +R+ E K+++ + + + +K K
Sbjct: 1731 KEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEK 1790
Query: 480 VPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTIS--GHRELVLSSPEDLTQDFEE 537
+P + + ++E E + AQK + ++ +++L ++L Q+ +
Sbjct: 1791 MP-----EEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKN 1845
Query: 538 MKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQ-EEHVMKEKELV 596
+ +E+ LA++++ L +K + ++ G + L Q EE + +EKE V
Sbjct: 1846 L-AQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKI--LAQVEEKLTQEKETV 1902
Query: 597 PEVPEEQGSKDRGL----DSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEV-KED 651
+ E+ ++ L DS A+ +E+ +EK + E+ + + R E ++ KE+
Sbjct: 1903 IKKKEKLAETEKKLVQVEDSLAKKQEK--LAQEKMKLALEKAMVQGKKRLRGELDIAKEE 1960
Query: 652 VIEKAELEEM-EEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFGGRELGLQGK 709
E++ + EE E +E +K E K+T +E F R+L L+ K
Sbjct: 1961 KALNLEMKRLAEEKMRLVEGKETLSKGE---TPETSRQRKMTQVEQELF-ERKLSLEEK 2015
Score = 47.8 bits (112), Expect = 2e-04
Identities = 83/390 (21%), Positives = 164/390 (42%), Gaps = 40/390 (10%)
Query: 296 QKDLASGAVPTNLKPSKIKQRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELAK- 354
+K LA + K+ ++ +K V +L +RE+ ++ KE EL +
Sbjct: 1662 RKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEEL 1721
Query: 355 -----ELAKTEKKAKESSEKPPE---KPAKPERVKTESSEALKAEKRKLIKDKVGKKHLK 406
EL+ E++ + K E K A+ E E L E+ KL +++ K
Sbjct: 1722 EWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEK 1781
Query: 407 EKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKP 466
EK+++ +EK +E++ + ++R++L + + + +K++ + TK ++ K +L
Sbjct: 1782 EKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNL-- 1839
Query: 467 FTPEVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLS 526
+ +K L + K A R E L ++ + ++K V + G +L+
Sbjct: 1840 --AQEKKNLAQEK--------EKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILA 1889
Query: 527 SPED-LTQDFEE-MKREERALLAEQR----DTGLGDKPFPLDTAEEGPPSTAIQGTPPSV 580
E+ LTQ+ E +K++E+ E++ + L K L A+E +
Sbjct: 1890 QVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKL--AQEKMKLALEKAMVQGK 1947
Query: 581 PGLGQEEHVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEA 640
L E + KE++ + + + L G ET + +T E +QR+ ++
Sbjct: 1948 KRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFE 2007
Query: 641 REESEPE-----------VKEDVIEKAELE 659
R+ S E ++E I K +LE
Sbjct: 2008 RKLSLEEKILLHEDRILAMEESEIAKGKLE 2037
Score = 45.1 bits (105), Expect = 0.001
Identities = 72/331 (21%), Positives = 133/331 (40%), Gaps = 34/331 (10%)
Query: 354 KELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLE 413
++LAK +K + E ++PAK ++ ++ + L ++RKL ++++ +K + E
Sbjct: 2050 RKLAKASRKLIKKRESLSKEPAKLNKI-LKALQKLTRDERKLTQEEIKMTKMKRALFVKE 2108
Query: 414 EKK--DKEKKEIKKERKELKKDEGRKEEKKDAKKEEK------------RKDTKPELKKI 459
+ ++ K +IK+ K+ E K+EKK A+K+ K K T+ E K
Sbjct: 2109 RRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLA 2168
Query: 460 SKPDLKPFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISG 519
K E + + +V +K R R KE A++G P S
Sbjct: 2169 RKHSEVILDDEEEGGIEEEEVIPFLK----RRWRKRKE---------AKRGDKPKEKFSS 2215
Query: 520 HRELVLSSP---EDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGT 576
+ V S E++ +E++++E E+ + ++ + EE +
Sbjct: 2216 QVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEG 2275
Query: 577 PPSVPGLGQEEHVMKEKELVPEVPEEQGS---KDRGLDSGAETEEEKDTWEEKKQREAER 633
+EE K+KE E +E+ + + S ETE D EE++ E
Sbjct: 2276 EEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEE 2335
Query: 634 LPDRTEAREESEPEVKEDVIEKAELEEMEEV 664
DR + + E + K + L E V
Sbjct: 2336 EVDREKEILKKEKQFKLQEQRRKSLRGRERV 2366
Score = 36.6 bits (83), Expect = 0.36
Identities = 86/404 (21%), Positives = 145/404 (35%), Gaps = 65/404 (16%)
Query: 308 LKPSKIKQRADS---KESLK-----ATTKTAVSKLAKREEVV---EEGAKEARSELAKEL 356
+KPSK ++R + K S K TK SK E + E G + A E+ +
Sbjct: 1076 IKPSKGQRRGQAGVKKHSQKWLRGLKKTKERDSKQMSTEPGLLEDESGTEAAPIEMEEAS 1135
Query: 357 AKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKK 416
++ + S K + E+ ++ AL ++ + I+DK KK +K+ K +KK
Sbjct: 1136 VYSQWSSSTSVIKLSKDVDSQEKDISKDHIALTLKRLQKIRDKRDKKATAQKLKKKHKKK 1195
Query: 417 DKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLY 476
KE K I +E ++ P KK+ R++
Sbjct: 1196 GKEAKVINEETTPPVMEQ-------------------PVTKKVKIQGRGASGISGRRSTA 1236
Query: 477 KAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFE 536
R + R A+R S QT ++ L T + + +L Q+
Sbjct: 1237 GDGSSWRDDLCRLMALR-----ISGSQTKMSENLNAELVTFAQEMLVDRHPSWELFQEIC 1291
Query: 537 EMKREERALLAEQRDTG-LGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKEL 595
+ ++E +L E D + + P+ E IQG + V++ KE+
Sbjct: 1292 PLLKKESKVLLEDLDWDVVPPEKKPIFIQEGAIREDMIQGV---------TQEVIRHKEV 1342
Query: 596 VPEVPEEQGSKDRGLDSGAETE--------------------EEKDTWEEKKQREAERLP 635
+P E+ K R + ET+ +E EEKK +
Sbjct: 1343 MPREEEQAQKKARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQKSPKQ 1402
Query: 636 DRTEAREESEPEVKEDVIEKAELEEMEEVHPSDEEEEDATKAEG 679
R ++E + + + K E + EEV EE K EG
Sbjct: 1403 GRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEG 1446
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 91.7 bits (226), Expect = 9e-18
Identities = 87/339 (25%), Positives = 177/339 (52%), Gaps = 53/339 (15%)
Query: 1352 RTSEQKKEPEPKDEVLQQKDKTL-----EHKEVVEPKDTAIYQKDEALHVKNEAVKQQDK 1406
RTS+++K+ E ++Q+ ++L + E + P+ A K E L + ++ K
Sbjct: 117 RTSKEEKKHEI--HLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLR---K 171
Query: 1407 ALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQ 1466
LE GR L+ A + ++ L ++ EE+ + EQ++++ E++++ EQ++ EQ
Sbjct: 172 ELESVGRQLQ----AEVENNQMLSLLNRRQEERLR--EQEERLREQEERLREQEERLCEQ 225
Query: 1467 KDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQT 1526
+++ E +++ EQ++R+ EQ+E++ E +++ +Q E+ + E ++R EQ
Sbjct: 226 EERLREQEERLREQEERLCEQEERLREHEERLCEQ----------EERLCEQEERLREQ- 274
Query: 1527 DKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLV- 1585
E++ EQ++++ E++++ EQ+ Q++ EQ + E+ + +EQE +
Sbjct: 275 ----EERLH--EQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLC 328
Query: 1586 -QEDKTRKPKMLE--EKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWR 1642
QE + ++LE EK E+ + EE+ E LLE+ + L E L+++ R R+Q+E+ W+
Sbjct: 329 EQEKLPGQERLLEEVEKLLEQERRQEEQ-ERLLERERLLEEVEELLEQERLRQQDERLWQ 387
Query: 1643 GQDVVQE--------------WQETSPTREEPAGEQKEL 1667
Q+ +QE W+ R EP +EL
Sbjct: 388 -QETLQELERLRELERMLELGWEALYEQRAEPRSGFEEL 425
Score = 82.8 bits (203), Expect = 4e-15
Identities = 66/269 (24%), Positives = 146/269 (54%), Gaps = 19/269 (7%)
Query: 1349 LKDRTSEQKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKAL 1408
L R E+ +E E + + +Q+++ E +E + ++ + +++E L + E + +Q++ L
Sbjct: 193 LNRRQEERLREQE--ERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERL 250
Query: 1409 -EQKGRDLEQKDTALEQKDKALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQK 1467
E + R EQ++ EQ+++ E +++ E++++ EQ++++ E++++ EQ++ EQ+
Sbjct: 251 REHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQE 310
Query: 1468 DKALEPKDKDLEQKDRVLEQ-----KEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRD 1522
++ E +++ EQ++R+ EQ +E++ EE +K L+Q+ R E ++ + E ++R
Sbjct: 311 ERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEE----QERLLE-RERL 365
Query: 1523 LEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQ- 1581
LE+ ++ EQ+ Q+ + ++ Q LE+ L + + LE +AL E
Sbjct: 366 LEEVEELLEQERLRQQDERLWQQETLQELER----LRELERMLELGWEALYEQRAEPRSG 421
Query: 1582 -ESLVQEDKTRKPKMLEEKSPEKVKAMEE 1609
E L E+K+ + K +K EE
Sbjct: 422 FEELNNENKSTLQLEQQVKELKKSGGAEE 450
Score = 64.7 bits (156), Expect = 1e-09
Identities = 89/393 (22%), Positives = 167/393 (42%), Gaps = 37/393 (9%)
Query: 1317 LTPDSSFS-KSPESLPGPALEDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTLE 1375
L P + S K+ + A + + W+ K PG+ + +KK + T
Sbjct: 7 LPPHPAMSEKTQQGKLAAAKKKLKAYWQRKSPGIPAGANRKKK-------INGSSPDTAT 59
Query: 1376 HKEVVEPKDTA--IYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKD 1433
P D+A IY + A E ++ Q + L + L + +L
Sbjct: 60 SGGYHSPGDSATGIYGEGRASSTTLEDLESQYQELAVALDSSSAIISQLTENINSLVRTS 119
Query: 1434 KDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQK-EKIP 1492
K EEK + K+ K Q L + A K + L+ + L ++ E +
Sbjct: 120 K--EEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVG 177
Query: 1493 EEKDKALDQ-KVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQAL 1551
+ ++ ++ S+ ++ E+ + E ++R EQ ++ EQ+ + EQ++++ E++++
Sbjct: 178 RQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLR 237
Query: 1552 EQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAMEEKL 1611
EQ+ Q++ E + E+ + EQE ++E + R + EE+ E+ + + E+
Sbjct: 238 EQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQ-EERLCEQEERLREQE 296
Query: 1612 EALLEKTKALGLEESLV--QEGRAREQEEKYWR-----GQDVV-------------QEWQ 1651
E L E+ + L +E + QE R REQEE+ GQ+ + QE Q
Sbjct: 297 ERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQ 356
Query: 1652 ETSPTREEPAGEQKELAPAWEDTSPEQDNRYWR 1684
E RE E +EL ++ +QD R W+
Sbjct: 357 ERLLERERLLEEVEELLE--QERLRQQDERLWQ 387
Score = 41.2 bits (95), Expect = 0.015
Identities = 60/317 (18%), Positives = 138/317 (43%), Gaps = 46/317 (14%)
Query: 312 KIKQRADSKESLKATTKTAVSKLAKREEVV---EEGAKEARSELAKE---LAKTEKKAKE 365
+++ ++ + L + +L ++EE + EE +E L ++ L + E++ +E
Sbjct: 179 QLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLRE 238
Query: 366 SSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKK 425
E+ E + ER++ E E L ++ +L + + + +E++ + EE+ ++++ +++
Sbjct: 239 QEERLCE---QEERLR-EHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLRE 294
Query: 426 ERKELKKDEG--RKEEKKDAKKEEKRKDTKPELKKISK-PDLKPFTPEVRKTLYKAKVPG 482
+ + L + E R++E++ ++EE+ ++ + L + K P + EV K L + +
Sbjct: 295 QEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQE 354
Query: 483 RVK--IDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHR-------------ELVLSS 527
+ ++R R + +EL + + + T+ E +
Sbjct: 355 EQERLLERERLLEEVEELLEQERLRQQDERLWQQETLQELERLRELERMLELGWEALYEQ 414
Query: 528 PEDLTQDFEEMKREERALL------AEQRDTGLGDKPFPLDTAEEGPP---STAIQG--- 575
+ FEE+ E ++ L E + +G ++P ++A P + QG
Sbjct: 415 RAEPRSGFEELNNENKSTLQLEQQVKELKKSGGAEEPRGSESAAAARPVAGAPVPQGAWM 474
Query: 576 ------TPPSVPGLGQE 586
TP PGLG E
Sbjct: 475 CGQAGWTPQEHPGLGGE 491
Score = 40.4 bits (93), Expect = 0.025
Identities = 47/183 (25%), Positives = 76/183 (41%), Gaps = 28/183 (15%)
Query: 1573 EENHQTQEQESLVQE-----DKTRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESL 1627
E NH +E ES+ ++ + + +L + E+++ EE+L
Sbjct: 165 ETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLRE-------------- 210
Query: 1628 VQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGRE 1687
QE R REQEE+ ++ ++E +E +EE EQ+E E+ EQ+ R E
Sbjct: 211 -QEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEE 269
Query: 1688 DVALEQDTY--WRELSCERKVWFPHELDGQGARPHYTEERESTFLDEGPDDEQEVPLREH 1745
+ +++ E CE++ L Q R E+ E E EQE LRE
Sbjct: 270 RLREQEERLHEQEERLCEQE----ERLREQEER--LCEQEERLREQEERLCEQEERLREQ 323
Query: 1746 ATR 1748
R
Sbjct: 324 EER 326
Score = 37.4 bits (85), Expect = 0.21
Identities = 79/359 (22%), Positives = 142/359 (39%), Gaps = 40/359 (11%)
Query: 360 EKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKV--GKKHLKEKISKLEEKKD 417
E +A ++ + E + V +SS A+ ++ + I V K+ K +I L +K
Sbjct: 76 EGRASSTTLEDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIH-LVQKLG 134
Query: 418 KEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYK 477
+ ++K + E E K + +++ + EL+ + + +L
Sbjct: 135 RSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLN 194
Query: 478 AKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEE 537
+ R++ R E+ L + + Q+ + +E L E+ + EE
Sbjct: 195 RRQEERLREQEERLREQEERLREQEERLCEQEERLR------EQEERLREQEERLCEQEE 248
Query: 538 MKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVP 597
RE L EQ + L ++ L EE QEE + +++E +
Sbjct: 249 RLREHEERLCEQEER-LCEQEERLREQEERLHE--------------QEERLCEQEERLR 293
Query: 598 EVPE---EQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREESE--------P 646
E E EQ + R + +EE+ +E++ E E+LP + EE E
Sbjct: 294 EQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQ 353
Query: 647 EVKEDVIEKAELEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFGGRELG 705
E +E ++E+ L +EEV E+E + E +Q QE L+ R RE ELG
Sbjct: 354 EEQERLLERERL--LEEVEELLEQERLRQQDERLWQ---QETLQELERLRELERMLELG 407
Score = 32.7 bits (73), Expect = 5.2
Identities = 51/206 (24%), Positives = 77/206 (37%), Gaps = 19/206 (9%)
Query: 487 DRSRAIRGEKELSS---EPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREER 543
D + I GE SS E Q+ V L + S + + L + +E K+ E
Sbjct: 68 DSATGIYGEGRASSTTLEDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEI 127
Query: 544 ALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQE-EHVMKEKELVPEVPEE 602
L+ + LG F L P + P V L E H+ KE E V +
Sbjct: 128 HLVQK-----LGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQA 182
Query: 603 QGSKDRGL--------DSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIE 654
+ ++ L + E EE EE+ + + ERL ++ E E E ++E
Sbjct: 183 EVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEER 242
Query: 655 KAELEEMEEVHPSD--EEEEDATKAE 678
E EE H E+EE + E
Sbjct: 243 LCEQEERLREHEERLCEQEERLCEQE 268
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 89.7 bits (221), Expect = 4e-17
Identities = 204/940 (21%), Positives = 311/940 (33%), Gaps = 181/940 (19%)
Query: 1776 SPVGLPPEEEDKLTRSP---FEIISPPASPPEMVGQRVPSAPGQESPIPDPKLMPHMKNE 1832
+P + ++ +K+ P + I P P+ ++P +++ P K ++ E
Sbjct: 235 TPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQ--RDASRPQTKQADIVRGE 292
Query: 1833 PTTPSWLADIPPWVPKDRPLPPAPLSPAPG----PPTPAPESHTPAPFSWGTAEYDSVVA 1888
PS + P P +P P P + PG P PA P+ + A+ V
Sbjct: 293 SVKPSLPSPSKP--PIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVK 350
Query: 1889 AVQEGAAELEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQ 1948
+ + P PLG A+ E+ +E P + ++ P K+ A
Sbjct: 351 PPVQPPGTTKP-PAQPLGPAKPPAQQTGSEKPSSEQPGPKA-LAQPPGVGKTPAQQPGPA 408
Query: 1949 TEPEQREPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAG 2008
P Q+ TP P + +Q L A + P+ G P + ++A G
Sbjct: 409 KPPTQQVGTPKP---------LAQQPGLQSPAKAPGPTKTPVQQPG--PGKIPAQQAGPG 457
Query: 2009 RNTSAEKELSSPISPKSLQSDTPTFSYAALAGPTVPPRPEPGPSMEP-----SLTPPA-- 2061
+ S Q PT + L GP PP +PGP+ P S PP+
Sbjct: 458 KT--------------SAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQ 503
Query: 2062 -----VPPRAPILSKGPSPPLNGNIL-------SCSPDRRSPSPKESGRSHWDDSTSDSE 2109
PP+ P +K PSP G+ S P + PSP + S
Sbjct: 504 PGSTKPPPQQPGPAK-PSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS--- 559
Query: 2110 LEKGAREQPEKEAQSPSPPHPIPMGSP-TLWP---ETEAHVSPPLDSHLGPARPSLDFPA 2165
+ G+ + + SPS P G P T+ P TE + P ++
Sbjct: 560 -QTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVC 618
Query: 2166 SAFGFSSLQPAPPQLPSPAEPRSAPCG-SLAFSGDRALALAPGPPTRTRHDEYLEVTKAP 2224
S GF+ P L E C A GD LA P P + T A
Sbjct: 619 SLCGFN----PNPHLTEVKEWLCLNCQMKRALGGD--LAPVPSSPQPKLKTAPVTTTSAV 672
Query: 2225 SLDSSLPQLPSPSSPGAPL--LSNLPRPASPALSEGSSSEATTPVISSVAERFSPSLEAA 2282
S S PQ SP AP LS P P P P++ SPS +A
Sbjct: 673 SKSSPQPQQTSPKKDAAPKQDLSKAPEPKKP-----------PPLVKQPTLHGSPSAKAK 721
Query: 2283 EQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLECSEA 2342
+ P A SL PAPP PS+P + + +
Sbjct: 722 Q----------PPEADSL-----SKPAPPKE--------PSVPSEQ---------DKAPV 749
Query: 2343 ATEKPSPFQV--PSEDCAANGPTETSPNPPGPAPAKAENEEAAACP-----AWERGAWPE 2395
A +KP ++ P+ D ++ T P+ P + +++ EE P A ++P
Sbjct: 750 ADDKPKQPKMVKPTTDLVSSSSATTKPDIPS-SKVQSQAEEKTTPPLKTDSAKPSQSFPP 808
Query: 2396 GAERSSRPDTLLSPEQPVCPAGGS-----GGPPSSASPEVEAGPQGCATEPRPHRGELSP 2450
E+ S D+ P PA S GP S + + + P EP+ + ++SP
Sbjct: 809 TGEKVSPFDSKAIPR----PASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSP 864
Query: 2451 SFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPPT--------- 2501
P+P G T GP P +T PT
Sbjct: 865 KPDAKPMPK------------------------GSPTPPGPRPTAGQTVPTPQQSPKPQE 900
Query: 2502 -SASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDP 2560
S S + S +D P P T L F +S P P
Sbjct: 901 QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNL--ISTAGQPGPHSQS 958
Query: 2561 PPLPQPDPRPSPPRPDVCMADPEGL-SSESGRVERLREKEKVQGRVGRRAPGKAKPASPA 2619
P P+P +P P+ + + + K++ + + KA+ A
Sbjct: 959 GPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTV 1018
Query: 2620 RRLDLRGKRSP---------TPGKGPADRASRAPPRPRST 2650
+R + K P P K P+P ST
Sbjct: 1019 KRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPEST 1058
Score = 83.6 bits (205), Expect = 3e-15
Identities = 322/1621 (19%), Positives = 574/1621 (35%), Gaps = 233/1621 (14%)
Query: 256 ANPTEKIVRVLFPGNAPQNKILEGLEKLRHLDFLRYPVATQKDLASGAVPTNLKPSKIKQ 315
++P ++ R PG Q GL K R D R + G P+ + + K
Sbjct: 90 SHPPKQSGRPPDPGRPAQ----PGLSKSRTTDTFR-----SEQKLPGRSPSTISLKESKS 140
Query: 316 RADSKESLKAT--------------TKTAVSKLAKREEVVEEGAKEARSELAKELAKTEK 361
R D KE K++ + V+K + + + A + + +++ + E+
Sbjct: 141 RTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQ 200
Query: 362 KAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKK 421
E KPP + P+ + + + L +D K ++ K++ + K
Sbjct: 201 GKPEGIIKPPLQQQPPKPIPKQQGPG----RDPLQQDGTPKSISSQQPEKIKSQPPGTGK 256
Query: 422 EIKKERKELKKDEGRKEEKKDAKKEEKRK-------DTKPELKKISKPDLK---PFTPEV 471
I+ + + D + ++DA + + ++ KP L SKP ++ P P
Sbjct: 257 PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPA 316
Query: 472 RKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQT--PPAQK-GTVPLPTISGHRELVLSSP 528
++ ++ PG K ++ K L+ +P T PP Q GT P + L + P
Sbjct: 317 QQPGHEKSQPGPAK-PPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA----QPLGPAKP 371
Query: 529 EDLTQDFEEMKREERALLAEQRDTGLGDKPFPLDTAEEGP--PSTAIQGTPPSV---PGL 583
E+ E+ A + G+G P + GP P T GTP + PGL
Sbjct: 372 PAQQTGSEKPSSEQPGPKALAQPPGVGKTP----AQQPGPAKPPTQQVGTPKPLAQQPGL 427
Query: 584 GQEEHVMKEKELVPEVPEEQGSKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREE 643
+ + P + G + ++ + Q P +
Sbjct: 428 QSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGP- 486
Query: 644 SEPEVKEDVIEKAELEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFGGRE 703
++P ++ K ++ P ++ A + Q+P P S++ G +
Sbjct: 487 AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSP-------QQPGSTKPPSQQP-GSAK 538
Query: 704 LGLQGKAPEKETSLFLSSLTTPAGATEHVSYIQDETIPGYSETEQTISDEEIHDEPEERP 763
Q +P K ++ T P T +Q T+ ++ +P +
Sbjct: 539 PSAQQPSPAKPSA---QQSTKPVSQTGSGKPLQPPTVSPSAK------------QPPSQG 583
Query: 764 AP----PRFHTSTYDLPGPEGAGPFEASQPADSAVPATSGKVYGTPETELTYPTNIVAAP 819
P P +T+ L PE A F + V + G P LT +
Sbjct: 584 LPKTICPLCNTTELLLHVPEKAN-FNTCTECQTTVCSLCGF---NPNPHLTEVKEWLCLN 639
Query: 820 LAEEEHVSSATSITECDKLSSFATSVAEDQSVASLTAPQTEETG--KSSLLLDTVTSIPS 877
+ + + T+ S S ++PQ ++T K + ++ P
Sbjct: 640 CQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPE 699
Query: 878 SRTEAT----QGLDYVPSAGTISPTSSLEEDKGFKSPPCEDFSVTGESEKRGEIIGKG-- 931
+ L PSA P E D K P ++ SV E +K K
Sbjct: 700 PKKPPPLVKQPTLHGSPSAKAKQPP---EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQ 756
Query: 932 ----------LSGERAVEEEEEETANVEMSEKLCSQYGTPVFSA-PGHALHPGEPALGEA 980
+S A + + ++ V+ + + SA P + P +
Sbjct: 757 PKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF 816
Query: 981 EERCLSPDDSTVKMASPPPSGPPSATHTPFHQSPVEEKSEPQDFQEADSWGDTKRTPGVG 1040
+ + + S K+ S P GP S + PV++K EP+ Q TK +P
Sbjct: 817 DSKAIPRPASDSKIISHP--GPSSESKGQKQVDPVQKKEEPKKAQ-------TKMSP--- 864
Query: 1041 KEDAAE----ETVKPGPEEGTLEKEEKVPPPR-SPQAQEA------------------PV 1077
K DA PGP + VP P+ SP+ QE P
Sbjct: 865 KPDAKPMPKGSPTPPGPRPTA---GQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPT 921
Query: 1078 NIDEGLTGCTIQLLPAQDKAIVFEIMEAGEPTGPILGAEALPGGLRTLPQEPGKPQKDEV 1137
E +TG + I AG+P GP +++ PG P +P +
Sbjct: 922 TPQETVTGKLFGFGASIFSQASNLISTAGQP-GP--HSQSGPGAPMKQAPAPSQPPTSQG 978
Query: 1138 LRYPDRSLSPEDAESLSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRWPEVSPEDTQSL 1197
P A+S+ V A ++ PK+ T + ++ P +D++SL
Sbjct: 979 PPKSTGQAPPAPAKSIPVKKETKAPAA-EKLEPKAEQAPTVKRTETEKKPPPI-KDSKSL 1036
Query: 1198 SLSEESPSKETSLDVSSKQLSPESLGTLQFGELNLGKEEMGHLMQAEDTSHHTAPMSV-- 1255
+ + T L+ S K PES L ELN+G ++ + + + +
Sbjct: 1037 TAEPQKAVLPTKLEKSPK---PESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFN 1093
Query: 1256 PEPHAATASPPTDGTTRYSAQTDITDDSLD-RKSPASSFSHSTPSGNGKYLPGAITSPDE 1314
P PH Q I+ D RK P + PSG P A P
Sbjct: 1094 PTPHLTEIQEWL--CLNCQTQRAISGQLGDIRKMPPA------PSG-----PKASPMP-- 1138
Query: 1315 HILTPDSSFSKSPESLPGPALEDIAIKWEDKVPGLKDRTSEQKKEPEPKDEVLQQKDKTL 1374
P S S+ P +V +K + E K E E +V+ +K K
Sbjct: 1139 ---VPTESSSQKTAVPP-------------QVKLVKKQEQEVKTEAE---KVILEKVKET 1179
Query: 1375 EHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDK 1434
E + P T +++E+ K++A Q+K K E+K E+K ++ E K
Sbjct: 1180 LSMEKIPPMVTTDQKQEESKLEKDKASALQEK----KPLPEEKKLIPEEEKIRS-EEKKP 1234
Query: 1435 DLEEKDKALEQKDKIPEEKDKA-LEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPE 1493
LEEK E K +PE K A EQK L+ + + E K + V E K+ P+
Sbjct: 1235 LLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQ--PQ 1292
Query: 1494 EKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQ 1553
K + L K + T +K++ P+Q +E+ +K +K D + Q
Sbjct: 1293 TKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQ 1352
Query: 1554 KYWA------LGQKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKVKAM 1607
+ + G + + ++ + T E++ L K + SP + +
Sbjct: 1353 QPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKL 1412
Query: 1608 EEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQDVVQEWQET---SPTREEPAGEQ 1664
E + ++LE + +E ++ + E + + Q+ Q ET + + EE Q
Sbjct: 1413 ESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQ 1472
Query: 1665 KELAPAWEDTSPEQDNRYWRGREDVALEQDTYWRELSCERKVWFPHELDGQGARPHYTEE 1724
+E ++ S ++D+ +D + K F ++ + R Y
Sbjct: 1473 EERKDTFKKDS----------QQDIPSSKDH-------KEKSEFVDDITTR--REPYDSV 1513
Query: 1725 RESTFLDEGPDDEQEVPLREHATRSPWASDFKDFQESSPQKGLEVERWLAESPVGLPPEE 1784
ES+ + P VP R+ T S +S ++++ Q E E ++ + + + +E
Sbjct: 1514 EESSESENSP-----VPQRKRRT-SVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADE 1567
Query: 1785 E 1785
+
Sbjct: 1568 D 1568
Score = 81.6 bits (200), Expect = 1e-14
Identities = 224/1043 (21%), Positives = 348/1043 (33%), Gaps = 179/1043 (17%)
Query: 1763 PQKGLEVERWLAESPVGLPPEEEDKLTRSPFEIISPPASPPEMVGQRVPSAPGQESPIPD 1822
P + + + LA+ P P + T++P + P P + G SA Q P
Sbjct: 411 PTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQ-QTGPTKP 469
Query: 1823 PKLMPHMKNEPTTPSWLADIPPWVPKD-RPLPPAPLSPAPGPPTPAPESHTPAPFSWGTA 1881
P +P P A PP P +P P S P P P P P+P G+
Sbjct: 470 PSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAK--PSPQQPGST 527
Query: 1882 EYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSH 1941
+ S + +A+ + P P + K + G+ P S S+K P +
Sbjct: 528 KPPSQQPGSAKPSAQ-QPSPAKPSAQQSTKPVSQ-TGSGKPLQPPTVSPSAKQPPSQGLP 585
Query: 1942 ATTEPEQTEPEQREPTPYPDERSFQYADIYEQMM--LTGLGPACPTREPPLGAAGDWPPC 1999
T P E P++ +F + + L G P P L +W C
Sbjct: 586 KTICPLCNTTELL--LHVPEKANFNTCTECQTTVCSLCGFNP-----NPHLTEVKEW-LC 637
Query: 2000 LS--TKEAAAGRNTSAEKELSSPISPKSLQSDTPTFSYAALAGP---TVPPRPEPGPSME 2054
L+ K A G SSP PK + T S + + P P+ + P +
Sbjct: 638 LNCQMKRALGGDLAPVP---SSP-QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQD 693
Query: 2055 PSLTP-PAVPP---RAPILSKGPS-----PPLNGNILSCSPDRRSPSPKESGRSH-WDDS 2104
S P P PP + P L PS PP ++ +P + P E ++ DD
Sbjct: 694 LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDK 753
Query: 2105 TSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFP 2164
++ K + + + P P S + + E +PPL + A+PS FP
Sbjct: 754 PKQPKMVKPTTDLVSSSSATTKPDIP----SSKVQSQAEEKTTPPLKT--DSAKPSQSFP 807
Query: 2165 ASAFGFSSL-QPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEVTKA 2223
+ S A P+ S ++ S P S G + + P + + + +
Sbjct: 808 PTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQV----DPVQKKEEPKKAQTKMS 863
Query: 2224 PSLDSSLPQLPSPSSPG--------APLLSNLPRPASP---------ALSEGSSSEATTP 2266
P D+ SP+ PG P P+P ++++ S+ TTP
Sbjct: 864 PKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTP 923
Query: 2267 VISSVAERFSPSLEAAEQESGELDPGMEPAAHS------------LWDLTPLSPAPPASL 2314
+ + F Q S + +P HS P S PP S
Sbjct: 924 QETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKST 983
Query: 2315 DLALAPAPSLPGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGPAP 2374
A PAP+ +P E A EK P +E TET PP
Sbjct: 984 GQA-PPAPAKS-------IPVKKETKAPAAEKLEP---KAEQAPTVKRTETEKKPPPIKD 1032
Query: 2375 AKAENEEAAACPAWERGAWPEGAERSSRPDTLLSPEQPVCPAG---GSGGPP--SSASPE 2429
+K+ E ++ P E+S +P++ P+C GS PP ++ +
Sbjct: 1033 SKSLTAEP------QKAVLPTKLEKSPKPESTC----PLCKTELNIGSKDPPNFNTCTEC 1082
Query: 2430 VEAGPQGCATEPRPHRGELSPSFLNPPLPPSIDDRDLSTEEVRLV-GRGGRRRVGGPGTT 2488
C P PH E+ L+ + R + G+ G R P +
Sbjct: 1083 KNQVCNLCGFNPTPHLTEIQEWLC------------LNCQTQRAISGQLGDIRKMPPAPS 1130
Query: 2489 G---GPCPVTDETPPTSASDSGSSQSDSDVPP-------------------------ETE 2520
G P PV E SS + VPP ET
Sbjct: 1131 GPKASPMPVPTE----------SSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETL 1180
Query: 2521 ECPSITAEAALDSDEDGDFLPVDKAGG-------------VSGTHHPRPGHDPPPLPQPD 2567
I D ++ L DKA + R P L +
Sbjct: 1181 SMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKK 1240
Query: 2568 PRPSPPR--PDVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASPARRLDLR 2625
P P + P+ + PE + + + +EK++GRV + + K P +++
Sbjct: 1241 PTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGK--QPQTKME-- 1296
Query: 2626 GKRSPTPGKGPAD-----RASRAPPRPRSTT--SQVTPAEEK-DGHSPMSKGLVNGLKAG 2677
G S TP P + + + P+P T QV P +EK + S +
Sbjct: 1297 GLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKS 1356
Query: 2678 PMALSSKGSSGAPVYVDLAYIPN 2700
P LS G S + L IP+
Sbjct: 1357 PQGLSDTGYSSDGISSSLGEIPS 1379
Score = 75.1 bits (183), Expect = 9e-13
Identities = 171/803 (21%), Positives = 247/803 (30%), Gaps = 158/803 (19%)
Query: 1928 SSHSSKVPEASKSHATTEPEQTEPE--------QREPTPYPDER---------------- 1963
S + E +K + EQ +PE Q+ P P P ++
Sbjct: 180 SDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSI 239
Query: 1964 -SFQYADIYEQMMLTGLGPACPTREP-------PLGAAGDWPPCLSTKEAAAGRNTSAEK 2015
S Q I Q TG PT+ P PL P TK+A R S +
Sbjct: 240 SSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP---QTKQADIVRGESVKP 296
Query: 2016 ELSSPISPKSLQSDTPTFSYAALAGPTVPPRPEPGPSMEPS---------------LTPP 2060
L SP P +Q TP A G + +PGP+ P+ + PP
Sbjct: 297 SLPSPSKPP-IQQPTPGKPPAQQPGHE---KSQPGPAKPPAQPSGLTKPLAQQPGTVKPP 352
Query: 2061 AVPP---RAPILSKGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSE-------- 2109
PP + P GP+ P S P P PK + T +
Sbjct: 353 VQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPT 412
Query: 2110 ----LEKGAREQP--EKEAQSPSPPH-PIPMGSPTLWPETEAHVSPPLDSHLGPARPSLD 2162
K +QP + A++P P P+ P P +A GP +P
Sbjct: 413 QQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472
Query: 2163 FPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEVTK 2222
P A PPQ P PA+P GS PP++ TK
Sbjct: 473 LPGPA-------KPPPQQPGPAKPPPQQPGSAK------------PPSQQPGS-----TK 508
Query: 2223 APSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFSPSLEAA 2282
P PQ P P+ P + P+ S S++ +P S + P +
Sbjct: 509 PP------PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP---VS 559
Query: 2283 EQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLECSEA 2342
+ SG+ PL P P S P+ LP + C L C+
Sbjct: 560 QTGSGK----------------PLQP-PTVSPSAKQPPSQGLPKTI------CPL-CNTT 595
Query: 2343 ATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAACPAWER---GAWPEGAER 2399
P + C T S P P E +E + G
Sbjct: 596 ELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPS 655
Query: 2400 SSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGP-QGCATEPRPHRGELSPSFLNPPLP 2458
S +P +P S P SP+ +A P Q + P P + P P L
Sbjct: 656 SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP--PLVKQPTLH 713
Query: 2459 PSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPPTSASDSGSSQSDSDVPPE 2518
S + E + + + + PV D+ P ++ S
Sbjct: 714 GSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSAT 773
Query: 2519 TEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPD-PRPSPPRPDV 2577
T+ P I + E+ P+ P G P PRP+ +
Sbjct: 774 TK--PDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKII 831
Query: 2578 CMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASPARRLDLRGKRSPTPGKGPA 2637
P S +V+ +++KE+ P KA+ K SP P P
Sbjct: 832 SHPGPSSESKGQKQVDPVQKKEE---------PKKAQT-----------KMSPKPDAKPM 871
Query: 2638 DRASRAPPRPRSTTSQVTPAEEK 2660
+ S PP PR T Q P ++
Sbjct: 872 PKGSPTPPGPRPTAGQTVPTPQQ 894
Score = 72.0 bits (175), Expect = 8e-12
Identities = 275/1395 (19%), Positives = 483/1395 (34%), Gaps = 269/1395 (19%)
Query: 490 RAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLAEQ 549
RA+ G+ L+ P +P + T P+ T S + SSP Q + +++ A +
Sbjct: 644 RALGGD--LAPVPSSPQPKLKTAPVTTTSAVSK---SSP----QPQQTSPKKDAAPKQDL 694
Query: 550 RDTGLGDKPFPL---DTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSK 606
KP PL T P + A Q PP L + KE P VP EQ
Sbjct: 695 SKAPEPKKPPPLVKQPTLHGSPSAKAKQ--PPEADSLSKPA---PPKE--PSVPSEQDKA 747
Query: 607 DRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIEKAELEEMEEVHP 666
D + + K T + A PD ++ +S+ E K K + + + P
Sbjct: 748 PVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFP 807
Query: 667 SDEEEEDATKAEGFYQKHMQEPLKVTP-RSREAFGGRELG-LQGKAPEKETSLFLS---- 720
E+ ++ + + P S E+ G +++ +Q K K+ +S
Sbjct: 808 PTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD 867
Query: 721 ------SLTTPAG----ATEHVSYIQDETIPGYSETEQTISDEEIHDEPEERPAPPRFHT 770
TP G A + V Q P +++ I D P+ +P P+
Sbjct: 868 AKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETV 927
Query: 771 -------------------STYDLPGP---EGAGPFEASQPADSAVPATSGKVYGTPETE 808
ST PGP G G PA S P + G T +
Sbjct: 928 TGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAP 987
Query: 809 LTYPTNIVAAPLAEEEHVSSATSITECDKLSSFATSVAEDQSVASLTAPQTEETGKSSLL 868
P + P+ +E +A + E ++ + T +TE K +
Sbjct: 988 ---PAPAKSIPVKKETKAPAAEKL--------------EPKAEQAPTVKRTETEKKPPPI 1030
Query: 869 LD--TVTSIPSSRTEATQGLDYVPSAGTISPTSSLEEDKGFKSPPCEDFSVTGESEKRGE 926
D ++T+ P T+ L+ P + P E + G K PP +F+
Sbjct: 1031 KDSKSLTAEPQKAVLPTK-LEKSPKPESTCPLCKTELNIGSKDPP--NFNTC-------- 1079
Query: 927 IIGKGLSGERAVEEEEEETANVEMSEKLCSQYGTPVFSAPGHALHPGE-PALGEAEERCL 985
E ++C+ G F+ H E L +R +
Sbjct: 1080 ---------------------TECKNQVCNLCG---FNPTPHLTEIQEWLCLNCQTQRAI 1115
Query: 986 SPDDSTVKMASPPPSGPPSATHTPFHQSPVEEKSEPQDFQEADSWGDTKRTPGVGKEDAA 1045
S ++ P PSGP K+ P S T P V
Sbjct: 1116 SGQLGDIRKMPPAPSGP---------------KASPMPVPTESSSQKTAVPPQVKLVKKQ 1160
Query: 1046 EETVKPGPEEGTLEK------EEKVPPPRSPQAQEAPVNIDEGLTGCTIQLLPAQDKAIV 1099
E+ VK E+ LEK EK+PP + ++ ++ +DKA
Sbjct: 1161 EQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLE-------------KDKASA 1207
Query: 1100 FEIMEAGEPTGPILGAEALPGGLRTLPQEPGKPQKDEVLRYPDRSLSPEDAESLSVLSVP 1159
+ + LP + +P+E +++ ++ +PED + L
Sbjct: 1208 LQ------------EKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTS 1255
Query: 1160 SPDTANQEPTPKSPCGLTEQYLHKDRWPEVSPEDTQSLSLSEESPS-------KETSLDV 1212
+P+ + KS + E+ L P+ E Q + E PS KE
Sbjct: 1256 APEEQKHD-LLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTT 1314
Query: 1213 SSKQLSPESLGTLQFGELNLGKEEMGHLMQAEDTSHHTAPMSVPEPHAATASPPTDGTTR 1272
+ + P+ T + ++ GKE+ + ED T+ P+ SP T
Sbjct: 1315 KTIKEQPQPPCTAKPDQVEPGKEK----TEKEDDKSDTSSSQQPK------SPQGLSDTG 1364
Query: 1273 YSAQTDITDDSLDRKSPASSFSHSTPSGNGKYLPGAITSPDEHILTPDSSFSKSPESLPG 1332
YS +D SL +P I + ++ IL S S ES P
Sbjct: 1365 YS--SDGISSSLGE------------------IPSLIPTDEKDILKGLKKDSFSQESSPS 1404
Query: 1333 -----PALEDIAIK-WEDKVPGLKDRTSEQKKEP------EPKDEVLQQKDKTLEHKEVV 1380
LE + E + L D SE+K +P +PKD Q+K ++L +
Sbjct: 1405 SPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKD---QEKTQSLSETLEI 1461
Query: 1381 EPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKDKALEPKDKDLEEKD 1440
+ I + E + + K+ + +D ++K ++ EP D +EE
Sbjct: 1462 TISEEEIKESQEE---RKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYD-SVEESS 1517
Query: 1441 KALEQKDKIPEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALD 1500
++ + +P+ K + ++ E K E E++D + +Q ++ ++D +
Sbjct: 1518 ES--ENSPVPQRKRRTSVGSSSSDEYKQ---EDSQGSGEEEDFIRKQIIEMSADEDASGS 1572
Query: 1501 QKVRSVEHKAPE--DTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWAL 1558
+ + ++ E + K + + K KH+ +K S +D +
Sbjct: 1573 EDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWH-- 1630
Query: 1559 GQKDEALEQNIQALEENHQTQEQESLV-------------QEDKTRKPKMLEEKSPEKVK 1605
+ DEA +++ + ++QE E LV + + T K E S +K
Sbjct: 1631 DEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTS 1690
Query: 1606 AMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQ-----DVVQEWQETSPTREEP 1660
++ L ++ E+ EG + + G + E ++SP+ ++
Sbjct: 1691 LYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKG 1750
Query: 1661 AGEQKE---------LAPAWEDTSPEQDNRYWRGREDVALEQ------DTYWRELSCERK 1705
+Q+ L P ED+S E++ R E++ EQ + R+ S ++
Sbjct: 1751 ESKQQRKARHRPHGPLLPTIEDSSEEEE---LREEEELLKEQEKQREIEQQQRKSSSKKS 1807
Query: 1706 VWFPHELDGQ--GARPHYTEERESTFLDEGPDDE-------QEVPLREHATRSPWASDFK 1756
EL Q RP S D P +E +E+ + SP
Sbjct: 1808 KKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDP 1867
Query: 1757 DFQESSPQKGLEVER 1771
+ E SP+K +EV++
Sbjct: 1868 EGFEISPEKIIEVQK 1882
Score = 54.7 bits (130), Expect = 1e-06
Identities = 197/993 (19%), Positives = 349/993 (35%), Gaps = 136/993 (13%)
Query: 372 EKPAKPERVKTESSEALKAEKRK------LIKDKVGKKHLKEKISKLEEKKDKEKKEIKK 425
+ + P K ES + KA R I+D ++ L+E+ L+E++ + + E ++
Sbjct: 1740 DSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQ 1799
Query: 426 ERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVK 485
+ KK + K+E + ++ E+ K L I D P T E+R+ ++
Sbjct: 1800 RKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIE--DASP-TEELRQAAEMEELHRSSC 1856
Query: 486 IDRSRAIRGEKE-LSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERA 544
+ S +I + E P+ + LPT + L SP D ++ ++
Sbjct: 1857 SEYSPSIESDPEGFEISPEKIIEVQKVYKLPT-----AVSLYSPTDEQSIMQKEGSQKAL 1911
Query: 545 LLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMK-----------EK 593
AE+ + K + P G+ E+++ + +
Sbjct: 1912 KSAEEMYEEMMHKTHKYKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDG 1971
Query: 594 ELVPEVPEEQG-SKDRGLDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVKEDV 652
L+ EE G + +G + E+ +E+ Q+ + + E +ED+
Sbjct: 1972 SLLTRQEEENGFMQQKGREQKIRLSEQ--IYEDPMQKITDLQKEFYELESLHSVVPQEDI 2029
Query: 653 I-------EKAELEEMEEVHPSDEEEEDATKAEGFYQKHM-QEPLKVTPRSR-------E 697
+ E E+ ++ + S EEE A+ Y++ M ++ +++TP S E
Sbjct: 2030 VSSSFIIPESHEIVDLGTMVTSTEEERKLLDADAAYEELMKRQQMQLTPGSSPTQAPIGE 2089
Query: 698 AFGGRELGLQGKAPEKETSLFLSSLTTPAGATEHVSYIQDETIPGYSETEQTISDEEIHD 757
+ TS LS + + I D I + TE+ I DE + D
Sbjct: 2090 DMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIPDVKITQHFSTEE-IEDEYVTD 2148
Query: 758 EPEERPAPPRFHT--STYDLPGPEGAGPFEASQPADSAVPATSGKVYGTPETELTYP-TN 814
E + TY P A+ S P+ + V T+ + P T
Sbjct: 2149 YTREIQEIIAHESLILTYSEPSE------SATSVPPSDTPSLTSSVSSVCTTDSSSPITT 2202
Query: 815 IVAAPLAEEEHVSSATSITECDKLSS---FATSVAEDQSVASLTAPQT-EETGKSSL--L 868
+ + E V T + +++SS F S+ + S++ +T G++S +
Sbjct: 2203 LDSITTVYTEPVDMITKFEDSEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHI 2262
Query: 869 LDTVTSIPSSRTEATQGLDYVPSAGTISPTSSLEEDKGFKSPPCEDFSVTGESEKRGEII 928
+ +++ + SS E+ P A T+S + E K + E II
Sbjct: 2263 VISLSDMASSIIESVVPKPEGPVADTVSTDLLISEKDPVKK---------AKKETGNGII 2313
Query: 929 GKGLSGERAVEEEEEETANVEMSEKLCSQYGTPVFSAP-GHALHPGEPALGEAEERCLSP 987
+ L R +E E E +SE + + V + P L GE
Sbjct: 2314 LEVLEAYRDKKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGET------- 2366
Query: 988 DDSTVKMASPPPSGPPSATHTPFHQSPVEEKSEPQDFQEADSWGDTKRTPGVGKEDAAEE 1047
K AS PSG PS + P ++P+ F + S + + P
Sbjct: 2367 -FGQEKPASQLPSGSPSVSSLP---------AKPRPFFRSSSLDISAQPPPPPPPPPPPP 2416
Query: 1048 TVKPGPEEGTLEKEEKVPPPRSPQAQEAPVN--------------IDEGLTGCTIQLLPA 1093
P P L PPP SP+ P D T T +L +
Sbjct: 2417 PPPPPPPPPPL------PPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRS 2470
Query: 1094 QDKAIVFEIMEAGEPTGPILGAEALPGGL----RTLPQEPGKPQKDEVLRYPDRSLSPED 1149
+ A P P ++P GL R P +P K + + P + P D
Sbjct: 2471 NGLPVTRICTTAPPPVPP--KPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTD 2528
Query: 1150 AESLSV-LSVPSPDTAN-------QEPTPKSPC-------------GLTEQYLHKDRWPE 1188
LS+ S T N + P+P SP LTE Y+ E
Sbjct: 2529 IHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSE 2588
Query: 1189 V-SPEDTQSLSLSEESPSKETSLDVSSKQLSPESLGTLQFGELNLGKEEMGHLMQAEDTS 1247
+P D+ + P S D+ S + + + E+ + E+ ++ A T
Sbjct: 2589 PGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTF 2648
Query: 1248 HHTAPMSVPEPHAATASPPTDGTTRYSAQTDIT 1280
T P++ P A + T T ++T+++
Sbjct: 2649 SAT-PVTAPSSFQAAPTSVTQFLTTEVSKTEVS 2680
Score = 47.0 bits (110), Expect = 3e-04
Identities = 99/494 (20%), Positives = 157/494 (31%), Gaps = 46/494 (9%)
Query: 2206 PGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASPALSEGSSSEATT 2265
PG D + K P S L S ++L ++ G SE
Sbjct: 108 PGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSR-----TDLKEEHKSSMMPGFLSEVNA 162
Query: 2266 -PVISSVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAPAPSL 2324
+SSV +F+P ++ E+ + + + P P L P +
Sbjct: 163 LSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPP---LQQQPPKPI 219
Query: 2325 PGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAA 2384
P G G P + + + P ++ S+ P + P AK + A+
Sbjct: 220 PKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDAS 279
Query: 2385 CPAWERGAWPEGAERSSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRPH 2444
P ++ G S +P +L SP +P G PP+ P E G A P
Sbjct: 280 RPQTKQADIVRG--ESVKP-SLPSPSKPPIQQPTPGKPPAQ-QPGHEKSQPGPAKPPAQP 335
Query: 2445 RGELSPSFLNP------------------PLPPSIDDRDLSTEEVRLVGRGGRRRVGGPG 2486
G P P PL P+ + E + G + + P
Sbjct: 336 SGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP 395
Query: 2487 TTG-------GPC-PVTDE--TPPTSASDSGSSQSDSDVPPETEECPSITAEAALDSDED 2536
G GP P T + TP A G QS + P T+ + + +
Sbjct: 396 GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGL-QSPAKAPGPTKTPVQQPGPGKIPAQQA 454
Query: 2537 GDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRPDVCMADPEGLSSESGRVERLR 2596
G + G + PG PP QP P PP+ P S+ +
Sbjct: 455 GPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPP----SQQPGSTKPP 510
Query: 2597 EKEKVQGRVGRRAPGKAKPASPARRLDLRGKRSPTPGKGPADRASRAPPRPRSTTSQVTP 2656
++ + + PG KP S + P+P K A ++++ + S P
Sbjct: 511 PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570
Query: 2657 AEEKDGHSPMSKGL 2670
P S+GL
Sbjct: 571 TVSPSAKQPPSQGL 584
Score = 47.0 bits (110), Expect = 3e-04
Identities = 70/345 (20%), Positives = 135/345 (39%), Gaps = 28/345 (8%)
Query: 303 AVPTNLKPSKIK-----QRADSKESLKATTKTAVSKLAKREEVVEEGAKEARSELA---K 354
A P ++P K K ++D+ S + + +S + + E S + K
Sbjct: 1327 AKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEK 1386
Query: 355 ELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKISKLEE 414
++ K KK S E P P+ ++++ L+A+ L +K KK ++S E+
Sbjct: 1387 DILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSP-EQ 1445
Query: 415 KKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKT 474
KD+EK + E E+ EE+ K+++ E K K D + P +
Sbjct: 1446 PKDQEKTQSLSETLEI------------TISEEEIKESQEERKDTFKKDSQQDIPSSKDH 1493
Query: 475 LYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQD 534
K++ + R E+ SE P +K + + S E + ++
Sbjct: 1494 KEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGS-SSSDEYKQEDSQGSGEE 1552
Query: 535 FEEMKREERALLAEQRDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQ---EEHVMK 591
+ ++++ + A++ +G D F + +E ST Q G G+ +H
Sbjct: 1553 EDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQ-KKEETKGKGKITAGKHRRL 1611
Query: 592 EKELVPEVPEEQGSKDRGLDSGAETEEEKD--TWEEKKQREAERL 634
++ + E+ G + D E +E + E K +E+E L
Sbjct: 1612 TRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEEL 1656
Score = 38.9 bits (89), Expect = 0.072
Identities = 65/287 (22%), Positives = 91/287 (31%), Gaps = 64/287 (22%)
Query: 1815 GQESPIPD-PKLMPHMKNEPTTP-----SWLADI---PPWVPKDRPLPPAPLSPAPGPPT 1865
GQE P P P + + P P S DI PP P P PP P P P PP
Sbjct: 2368 GQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPL 2427
Query: 1866 PAPESHTP-----------APFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEG 1914
P P S P +P + T +D+V G P + +
Sbjct: 2428 PPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRI--------- 2478
Query: 1915 EREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQYADIYEQM 1974
P S +P EP + + P + + DI+ +
Sbjct: 2479 -----CTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKP 2533
Query: 1975 MLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSD--TPT 2032
TGL T TSA+ +L SP SP S S+ +P
Sbjct: 2534 --TGLS--------------------LTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPR 2571
Query: 2033 FS------YAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGP 2073
FS Y + P+ P P + + + P P ++S P
Sbjct: 2572 FSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEP 2618
Score = 35.0 bits (79), Expect = 1.0
Identities = 68/311 (21%), Positives = 102/311 (32%), Gaps = 54/311 (17%)
Query: 2000 LSTKEAAAGRNTSAEKELSS-PISPKSLQS----DTPTFSYAALAGPTVPPRPEPGPSME 2054
LST +G EK S P S+ S P F ++L PP P P P
Sbjct: 2356 LSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPP 2415
Query: 2055 PSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEKGA 2114
P PP PP P PP + + + + + + D+ + E
Sbjct: 2416 PPPPPPPPPPPLP-------PPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVL 2468
Query: 2115 REQ---------------PEKEAQSPS--------PPHPIPMGSPTLWPETEAHVSPPLD 2151
R P K + PS P P+ + P+ P D
Sbjct: 2469 RSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTD 2528
Query: 2152 SHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEP------RSAPCGSLAFSGDRALALA 2205
H P SL S+ + + A +LPSP P +S+P S + + +
Sbjct: 2529 IHPKPTGLSL---TSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITL 2585
Query: 2206 PGPP-TRTRHDEYLEVTKAP---------SLDSSLPQLPSPSSPGAPLLSNLPRPASPAL 2255
P P T T +T P S++ +P ++ P+ S S AL
Sbjct: 2586 PSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGAL 2645
Query: 2256 SEGSSSEATTP 2266
S++ T P
Sbjct: 2646 QTFSATPVTAP 2656
Score = 33.1 bits (74), Expect = 4.0
Identities = 54/267 (20%), Positives = 108/267 (40%), Gaps = 36/267 (13%)
Query: 281 EKLRHLDFLRYPVATQKDLASGAVPTNLKPSKIKQRA--DSKESLKATTKTAVSKLAKRE 338
+K+ H D + P P + K +K+ QR+ D K +++ + E
Sbjct: 3654 QKVLHPDMAKVP------------PASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTE 3701
Query: 339 EVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKD 398
+G++ S A +KK K + PP + T S+ + +R +
Sbjct: 3702 GYTTKGSQTMTSSGA------QKKVKRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTN 3755
Query: 399 KVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEK-----------KDAKKEE 447
+ + + + I + + ++E +++K++ EL ++E + K K+A +E
Sbjct: 3756 TMARAKILQDIDRELDLVERESAKLRKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKE 3815
Query: 448 KRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVKIDRSR-AIRGEKELSSEPQTPP 506
+ K + L+ +++ EV T ++ + I+R R A + E PQT
Sbjct: 3816 REKRERAYLQGVAEDRDYMSDSEVSST-RPTRIESQHGIERPRTAPQTEFSQFIPPQT-- 3872
Query: 507 AQKGTVPLPTISGHRELVLSSPEDLTQ 533
Q + +P S + + SSP TQ
Sbjct: 3873 -QTESQLVPPTSPYTQYQYSSPALPTQ 3898
Score = 32.7 bits (73), Expect = 5.2
Identities = 20/75 (26%), Positives = 29/75 (38%), Gaps = 10/75 (13%)
Query: 2501 TSASDSGSSQSDSDVPPETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDP 2560
TS G + S +P + S+ A+ P ++ + + P P P
Sbjct: 2362 TSGETFGQEKPASQLPSGSPSVSSLPAKPR----------PFFRSSSLDISAQPPPPPPP 2411
Query: 2561 PPLPQPDPRPSPPRP 2575
PP P P P P PP P
Sbjct: 2412 PPPPPPPPPPPPPPP 2426
Score = 32.0 bits (71), Expect = 8.8
Identities = 91/419 (21%), Positives = 131/419 (31%), Gaps = 76/419 (18%)
Query: 2302 DLTPLSPAPPASLDLALAPAPSLPGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANG 2361
DL+ LS + ++ A LP G +P AA E PS + ++ ++
Sbjct: 44 DLSQLSEEERRQIAAVMSRAQGLP----KGSVP------PAAAESPSMHR--KQELDSSH 91
Query: 2362 PTETSPNPPGPAPAKAENEEAAACPAWERGAWPEGAERSSRPDTLLSPEQPVCPAGGSGG 2421
P + S PP P R A P G +S DT S ++ G
Sbjct: 92 PPKQSGRPPDPG----------------RPAQP-GLSKSRTTDTFRSEQKL------PGR 128
Query: 2422 PPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPPLPPS--------------IDDRDLS 2467
PS+ S + E H+ + P FL+ S I D + S
Sbjct: 129 SPSTISLKESKSRTDLKEE---HKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEAS 185
Query: 2468 TEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPPTSASDSGSSQSDSDVPPETEECPSITA 2527
EE + ++ G P G P + PP D T + S
Sbjct: 186 QEETTKKQKVVQKEQGKP--EGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQ 243
Query: 2528 EAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRPDVCMADPEGLSS 2587
+ S G P+ T P+ H PL + RP + D+ + S
Sbjct: 244 PEKIKSQPPGTGKPIQ-----GPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSL 298
Query: 2588 ESGRVERLREKEKVQGRVGRRAPGKAKPASPARRLDLRGKRSPTPGKGPADRASRAPPRP 2647
S K +Q + PGK P K P P K PA + P
Sbjct: 299 PSP------SKPPIQ----QPTPGKPPAQQPGHE-----KSQPGPAKPPAQPSGLTKPLA 343
Query: 2648 RSTTSQVTPAEEKDGHSPMSKGLVNGLKAGPMALSSKGSSGAPVYVDLAYIPNHCSGKT 2706
+ + P + P ++ L S K SS P LA P GKT
Sbjct: 344 QQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPG--VGKT 400
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.127 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 142,480,944
Number of Sequences: 37866
Number of extensions: 9365846
Number of successful extensions: 114759
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 836
Number of HSP's successfully gapped in prelim test: 3227
Number of HSP's that attempted gapping in prelim test: 37294
Number of HSP's gapped (non-prelim): 43274
length of query: 2803
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2683
effective length of database: 13,703,598
effective search space: 36766753434
effective search space used: 36766753434
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.