Guide to the Human Genome
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Search of human proteins with 94536858

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|94536858 kinesin family member C3 isoform 1 [Homo sapiens]
         (833 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|94536858 kinesin family member C3 isoform 1 [Homo sapiens]        1635   0.0  
gi|194294510 kinesin family member C3 isoform 2 [Homo sapiens]       1618   0.0  
gi|194294508 kinesin family member C3 isoform 3 [Homo sapiens]       1334   0.0  
gi|21955174 kinesin family member C2 [Homo sapiens]                   289   6e-78
gi|167555110 kinesin family member C1 [Homo sapiens]                  265   1e-70
gi|46852174 kinesin family member 3A [Homo sapiens]                   249   6e-66
gi|4758646 kinesin family member 3B [Homo sapiens]                    239   6e-63
gi|4758648 kinesin family member 5B [Homo sapiens]                    222   1e-57
gi|41352705 kinesin family member 3C [Homo sapiens]                   221   2e-57
gi|116686122 kinesin family member 4 [Homo sapiens]                   215   1e-55
gi|170784809 kinesin family member 17 isoform b [Homo sapiens]        215   1e-55
gi|170784807 kinesin family member 17 isoform a [Homo sapiens]        215   1e-55
gi|150010604 kinesin family member 4B [Homo sapiens]                  213   6e-55
gi|4758650 kinesin family member 5C [Homo sapiens]                    213   6e-55
gi|45446749 kinesin family member 5A [Homo sapiens]                   213   6e-55
gi|46852172 kinesin family member 13B [Homo sapiens]                  212   1e-54
gi|40254834 kinesin family member 1C [Homo sapiens]                   208   2e-53
gi|13699824 kinesin family member 11 [Homo sapiens]                   203   6e-52
gi|122937289 kinesin family member 18B [Homo sapiens]                 203   6e-52
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]        202   1e-51
gi|156616271 kinesin family member 19 [Homo sapiens]                  201   2e-51
gi|30794488 kinesin family member 27 [Homo sapiens]                   201   3e-51
gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]     200   4e-51
gi|41393563 kinesin family member 1B isoform b [Homo sapiens]         200   4e-51
gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]      199   9e-51
gi|157738629 kinesin family member 13A isoform d [Homo sapiens]       196   7e-50
gi|157738627 kinesin family member 13A isoform c [Homo sapiens]       196   7e-50
gi|157738625 kinesin family member 13A isoform b [Homo sapiens]       196   7e-50
gi|157738621 kinesin family member 13A isoform a [Homo sapiens]       196   7e-50
gi|7661878 kinesin family member 14 [Homo sapiens]                    194   4e-49

>gi|94536858 kinesin family member C3 isoform 1 [Homo sapiens]
          Length = 833

 Score = 1635 bits (4233), Expect = 0.0
 Identities = 833/833 (100%), Positives = 833/833 (100%)

Query: 1   MVPSRRTWNLGATPSLRGLWRVGRAPEPEPGMARPAPAPASPAARPFPHTGPGRLRTGRG 60
           MVPSRRTWNLGATPSLRGLWRVGRAPEPEPGMARPAPAPASPAARPFPHTGPGRLRTGRG
Sbjct: 1   MVPSRRTWNLGATPSLRGLWRVGRAPEPEPGMARPAPAPASPAARPFPHTGPGRLRTGRG 60

Query: 61  KDTPVCGDEDSSARSAARPALAQCRALSVDWAGPGSPHGLYLTLQVEHLKEKLISQAQEV 120
           KDTPVCGDEDSSARSAARPALAQCRALSVDWAGPGSPHGLYLTLQVEHLKEKLISQAQEV
Sbjct: 61  KDTPVCGDEDSSARSAARPALAQCRALSVDWAGPGSPHGLYLTLQVEHLKEKLISQAQEV 120

Query: 121 SRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQL 180
           SRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQL
Sbjct: 121 SRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQL 180

Query: 181 RDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDS 240
           RDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDS
Sbjct: 181 RDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDS 240

Query: 241 HETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQL 300
           HETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQL
Sbjct: 241 HETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQL 300

Query: 301 QSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHEN 360
           QSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHEN
Sbjct: 301 QSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHEN 360

Query: 361 LAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQE 420
           LAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQE
Sbjct: 361 LAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQE 420

Query: 421 LLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIH 480
           LLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIH
Sbjct: 421 LLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIH 480

Query: 481 LLHKGKPVSFELDKVFSPQASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEG 540
           LLHKGKPVSFELDKVFSPQASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEG
Sbjct: 481 LLHKGKPVSFELDKVFSPQASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEG 540

Query: 541 TAENPGINQRALQLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCP 600
           TAENPGINQRALQLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCP
Sbjct: 541 TAENPGINQRALQLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCP 600

Query: 601 DGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDC 660
           DGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDC
Sbjct: 601 DGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDC 660

Query: 661 STGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPF 720
           STGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPF
Sbjct: 661 STGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPF 720

Query: 721 RNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELG 780
           RNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELG
Sbjct: 721 RNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELG 780

Query: 781 SWSSQEHLEWEPACQTPQPSARAHSAPSSGTSSRPGSIRRKLQPSGKSRPLPV 833
           SWSSQEHLEWEPACQTPQPSARAHSAPSSGTSSRPGSIRRKLQPSGKSRPLPV
Sbjct: 781 SWSSQEHLEWEPACQTPQPSARAHSAPSSGTSSRPGSIRRKLQPSGKSRPLPV 833


>gi|194294510 kinesin family member C3 isoform 2 [Homo sapiens]
          Length = 826

 Score = 1618 bits (4191), Expect = 0.0
 Identities = 825/825 (100%), Positives = 825/825 (100%)

Query: 1   MVPSRRTWNLGATPSLRGLWRVGRAPEPEPGMARPAPAPASPAARPFPHTGPGRLRTGRG 60
           MVPSRRTWNLGATPSLRGLWRVGRAPEPEPGMARPAPAPASPAARPFPHTGPGRLRTGRG
Sbjct: 1   MVPSRRTWNLGATPSLRGLWRVGRAPEPEPGMARPAPAPASPAARPFPHTGPGRLRTGRG 60

Query: 61  KDTPVCGDEDSSARSAARPALAQCRALSVDWAGPGSPHGLYLTLQVEHLKEKLISQAQEV 120
           KDTPVCGDEDSSARSAARPALAQCRALSVDWAGPGSPHGLYLTLQVEHLKEKLISQAQEV
Sbjct: 61  KDTPVCGDEDSSARSAARPALAQCRALSVDWAGPGSPHGLYLTLQVEHLKEKLISQAQEV 120

Query: 121 SRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQL 180
           SRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQL
Sbjct: 121 SRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQL 180

Query: 181 RDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDS 240
           RDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDS
Sbjct: 181 RDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDS 240

Query: 241 HETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQL 300
           HETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQL
Sbjct: 241 HETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQL 300

Query: 301 QSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHEN 360
           QSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHEN
Sbjct: 301 QSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHEN 360

Query: 361 LAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQE 420
           LAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQE
Sbjct: 361 LAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQE 420

Query: 421 LLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIH 480
           LLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIH
Sbjct: 421 LLRKYRRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIH 480

Query: 481 LLHKGKPVSFELDKVFSPQASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEG 540
           LLHKGKPVSFELDKVFSPQASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEG
Sbjct: 481 LLHKGKPVSFELDKVFSPQASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEG 540

Query: 541 TAENPGINQRALQLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCP 600
           TAENPGINQRALQLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCP
Sbjct: 541 TAENPGINQRALQLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCP 600

Query: 601 DGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDC 660
           DGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDC
Sbjct: 601 DGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDC 660

Query: 661 STGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPF 720
           STGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPF
Sbjct: 661 STGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPF 720

Query: 721 RNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELG 780
           RNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELG
Sbjct: 721 RNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELG 780

Query: 781 SWSSQEHLEWEPACQTPQPSARAHSAPSSGTSSRPGSIRRKLQPS 825
           SWSSQEHLEWEPACQTPQPSARAHSAPSSGTSSRPGSIRRKLQPS
Sbjct: 781 SWSSQEHLEWEPACQTPQPSARAHSAPSSGTSSRPGSIRRKLQPS 825


>gi|194294508 kinesin family member C3 isoform 3 [Homo sapiens]
          Length = 687

 Score = 1334 bits (3452), Expect = 0.0
 Identities = 686/686 (100%), Positives = 686/686 (100%)

Query: 140 MVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLS 199
           MVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLS
Sbjct: 1   MVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLS 60

Query: 200 ELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIK 259
           ELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIK
Sbjct: 61  ELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIK 120

Query: 260 TVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYES 319
           TVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYES
Sbjct: 121 TVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYES 180

Query: 320 ELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLT 379
           ELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLT
Sbjct: 181 ELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLT 240

Query: 380 NDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNEL 439
           NDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNEL
Sbjct: 241 NDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNEL 300

Query: 440 VRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQ 499
           VRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQ
Sbjct: 301 VRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQ 360

Query: 500 ASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEV 559
           ASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEV
Sbjct: 361 ASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEV 420

Query: 560 QEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSV 619
           QEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSV
Sbjct: 421 QEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSV 480

Query: 620 DDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSE 679
           DDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSE
Sbjct: 481 DDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSE 540

Query: 680 RVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKT 739
           RVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKT
Sbjct: 541 RVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKT 600

Query: 740 LMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQP 799
           LMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQP
Sbjct: 601 LMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELGSWSSQEHLEWEPACQTPQP 660

Query: 800 SARAHSAPSSGTSSRPGSIRRKLQPS 825
           SARAHSAPSSGTSSRPGSIRRKLQPS
Sbjct: 661 SARAHSAPSSGTSSRPGSIRRKLQPS 686


>gi|21955174 kinesin family member C2 [Homo sapiens]
          Length = 838

 Score =  289 bits (740), Expect = 6e-78
 Identities = 197/561 (35%), Positives = 303/561 (54%), Gaps = 55/561 (9%)

Query: 201 LNLEVQQKT-DRLAEVEL-RLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVI 258
           L LE  Q+   RL ++ L +L++   +  Q+EE L R       T +  R Q        
Sbjct: 186 LQLEEDQRAWQRLEQLILGQLEELKQQLEQQEEELGRLRLGVGATDSEKRVQH------- 238

Query: 259 KTVEVESSKTKQALSESQARNQHLQEQVAM-----QRQVLKEMEQQLQSSHQLTARLRAQ 313
             + +E+   KQ+LS  +    H      +     + + L E++ +LQ +   T  LRAQ
Sbjct: 239 --LTLENEALKQSLSLMRDLLLHWGPGPPIRAPQEEAEALLELQGRLQEAQDTTEALRAQ 296

Query: 314 IAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQP 373
           + + E +L+   G + +  Q  E++  R           E++ +H  LAG+R  + +L+ 
Sbjct: 297 LGVQEVQLQGLQGALQQLQQETEQNCRR-----------ELQQMHGQLAGLRARMASLRQ 345

Query: 374 ALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRK 433
                  D  GL   V  F    Q +L   + ++  A+  ++S          ++     
Sbjct: 346 GC----GDLRGL---VSTFTQSCQGSLSEARGQVSWALGALSSGGPGTQLPEGQQGP-PA 397

Query: 434 KCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELD 493
            C   L  LKGNIRV+ R+RP T        +++ V+ +      +   ++G+   F LD
Sbjct: 398 GCPGRLPELKGNIRVLCRLRPGT--------SSSLVSVEPGPGGTVTTCYRGRHRRFRLD 449

Query: 494 KVFSPQASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQ 553
            VF P ASQ++VF+E++  V SC+ G++VCIF YGQTG GKTY+MEG  E+PGI  RALQ
Sbjct: 450 WVFPPDASQEEVFRELEPAVLSCLRGYSVCIFTYGQTGTGKTYSMEGPPEDPGIVPRALQ 509

Query: 554 LLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTE 613
            LF E+    +  ++ +T+S  EIYNE +RDLL   P E+L +R  P+G G + V GLT 
Sbjct: 510 SLFREM---GAGRQHRVTLSMVEIYNEAVRDLLAPGPPERLAVRQGPEGQGGIQVAGLTH 566

Query: 614 FQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLV 673
           + V +++ ++++ + G +NR T  T +N+ SSRSHAL+ +T+R         T G L+LV
Sbjct: 567 WDVPNLETLHQMLKLGRSNRATAATAMNQRSSRSHALVTLTLRAASPPRAPGTAGTLHLV 626

Query: 674 DLAGSERVGKSGAEG---------SRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSK 724
           DLAGSER  K+GA G          RLREAQ IN+SL ALG V+AALR+ + HVPFR+S+
Sbjct: 627 DLAGSERARKAGAAGPPRGDPDGARRLREAQTINRSLLALGGVMAALRAHRPHVPFRDSQ 686

Query: 725 LTYLLQDSLSGDSKTLMVVQV 745
           LT LLQ +L   +  ++++QV
Sbjct: 687 LTRLLQPALGPGTTAVLLLQV 707



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 49/148 (33%), Positives = 74/148 (50%), Gaps = 15/148 (10%)

Query: 105 QVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRTKP 164
           Q+E LK++L  Q +E+ RLR  +G TD EK    L +ENE L+Q +      L       
Sbjct: 205 QLEELKQQLEQQEEELGRLRLGVGATDSEKRVQHLTLENEALKQSLSLMRDLLLHW---- 260

Query: 165 AGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELR-LKDCL 223
            GP P     QE A   + L +LQ  + E++     L  ++      + EV+L+ L+  L
Sbjct: 261 -GPGPPIRAPQEEA---EALLELQGRLQEAQDTTEALRAQL-----GVQEVQLQGLQGAL 311

Query: 224 AEKAQEEERLSRR-LRDSHETIASLRAQ 250
            +  QE E+  RR L+  H  +A LRA+
Sbjct: 312 QQLQQETEQNCRRELQQMHGQLAGLRAR 339


>gi|167555110 kinesin family member C1 [Homo sapiens]
          Length = 673

 Score =  265 bits (678), Expect = 1e-70
 Identities = 189/543 (34%), Positives = 271/543 (49%), Gaps = 54/543 (9%)

Query: 261 VEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESE 320
           +  E  + ++        NQ LQ+Q+   +Q +K +  +  +     A+++AQ    + E
Sbjct: 146 LNAELKRCRERTQTLDQENQQLQDQLRDAQQQVKALGTERTTLEGHLAKVQAQAEQGQQE 205

Query: 321 LE--RAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTL 378
           L+  RA    LEE  S +E   + +++     Q E + +   L      L T + AL + 
Sbjct: 206 LKNLRACVLELEERLSTQEGLVQELQKKQVELQEERRGLMSQLEEKERRLQTSEAALSSS 265

Query: 379 TNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNE 438
             +   L+++      LL E                    +E L     E   R++ HN+
Sbjct: 266 QAEVASLRQETVAQAALLTE-------------------REERLHGLEME---RRRLHNQ 303

Query: 439 LVRLKGNIRVIARVRPVTKEDGEGP--------------EATNAVTFDADDDSIIHLLHK 484
           L  LKGNIRV  RVRPV   +   P              +    ++    D+    L   
Sbjct: 304 LQELKGNIRVFCRVRPVLPGEPTPPPGLLLFPSGPGGPSDPPTRLSLSRSDERRGTLSGA 363

Query: 485 GKPVS---FELDKVFSPQASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEG- 540
             P +   F  D+VF P + Q +VF+E+  LV S +DG+ VCIFAYGQTG+GKT+TMEG 
Sbjct: 364 PAPPTRHDFSFDRVFPPGSGQDEVFEEIAMLVQSALDGYPVCIFAYGQTGSGKTFTMEGG 423

Query: 541 ---TAENPGINQRALQLLFSEVQEKASD-WEYTITVSAAEIYNEVLRDLLGKEPQE---- 592
                +  G+  RAL+ LFS  QE +   W Y+   S  EIYNE +RDLL    ++    
Sbjct: 424 PGGDPQLEGLIPRALRHLFSVAQELSGQGWTYSFVASYVEIYNETVRDLLATGTRKGQGG 483

Query: 593 KLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLI 652
           + EIR    GS +L V       V    +++ +      NR    T  NE SSRSH++  
Sbjct: 484 ECEIRRAGPGSEELTVTNARYVPVSCEKEVDALLHLARQNRAVARTAQNERSSRSHSVFQ 543

Query: 653 VTVRGVDCSTGLRTTGKLNLVDLAGSERVGKSGAEG----SRLREAQHINKSLSALGDVI 708
           + + G   S GL+    L+LVDLAGSER+    A G     RLRE Q IN SLS LG VI
Sbjct: 544 LQISGEHSSRGLQCGAPLSLVDLAGSERLDPGLALGPGERERLRETQAINSSLSTLGLVI 603

Query: 709 AALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSV 768
            AL +++ HVP+RNSKLTYLLQ+SL G +K LM V +SP+E+N SE+L SL+FA +V   
Sbjct: 604 MALSNKESHVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVNQC 663

Query: 769 ELG 771
            +G
Sbjct: 664 VIG 666



 Score = 34.3 bits (77), Expect = 0.49
 Identities = 43/174 (24%), Positives = 71/174 (40%), Gaps = 22/174 (12%)

Query: 142 ENERLRQEMRRCEAELQEL---RTKPAGPCPGCEHSQESAQLRDK-LSQLQLEMAESKGM 197
           EN++L+ ++R  + +++ L   RT   G     +   E  Q   K L    LE+ E    
Sbjct: 163 ENQQLQDQLRDAQQQVKALGTERTTLEGHLAKVQAQAEQGQQELKNLRACVLELEERLST 222

Query: 198 LSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYV 257
              L  E+Q+K   L E    L   L EK +  +     L  S   +ASLR         
Sbjct: 223 QEGLVQELQKKQVELQEERRGLMSQLEEKERRLQTSEAALSSSQAEVASLRQ-------- 274

Query: 258 IKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLR 311
                 E+      L+E + R   L+    M+R+ L    Q+L+ + ++  R+R
Sbjct: 275 ------ETVAQAALLTEREERLHGLE----MERRRLHNQLQELKGNIRVFCRVR 318


>gi|46852174 kinesin family member 3A [Homo sapiens]
          Length = 699

 Score =  249 bits (637), Expect = 6e-66
 Identities = 141/337 (41%), Positives = 211/337 (62%), Gaps = 16/337 (4%)

Query: 445 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSI-IHLLHKGK--PVSFELDKVFSPQAS 501
           N++V+ R RP+ + + +      AV+ D    +I +H        P +F  D VF P++ 
Sbjct: 14  NVKVVVRCRPLNERE-KSMCYKQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESK 72

Query: 502 QQDVFQ-EVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP---GINQRALQLLFS 557
           Q DV+    + ++ S ++G+N  IFAYGQTG GKT+TMEG    P   GI   +   +F 
Sbjct: 73  QLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIPNSFAHIFG 132

Query: 558 EVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQ 617
            + +   D  + + VS  EIYNE +RDLLGK+  ++LE++  PD    +Y+  L+ + V 
Sbjct: 133 HIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVG--VYIKDLSAYVVN 190

Query: 618 SVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTV----RGVDCSTGLRTTGKLNLV 673
           + DD++++   GH NR+   TN+NEHSSRSHA+  +T+    +G+D +  +R  GKL+LV
Sbjct: 191 NADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRM-GKLHLV 249

Query: 674 DLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL-RSRQGHVPFRNSKLTYLLQDS 732
           DLAGSER  K+GA G RL+EA  IN SLS LG+VI+AL   +  HVP+RNSKLT LLQDS
Sbjct: 250 DLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDS 309

Query: 733 LSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVE 769
           L G+SKT+M   + P + N  ET+ +L++A R ++++
Sbjct: 310 LGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIK 346



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 48/218 (22%), Positives = 93/218 (42%), Gaps = 48/218 (22%)

Query: 132 LEKHRDLLMVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEM 191
           LE   D+   E  + R E+ + E +L + +             QE   L +KLS L+ ++
Sbjct: 433 LETKLDMEEEERNKARAELEKREKDLLKAQ-------------QEHQSLLEKLSALEKKV 479

Query: 192 A-----------ESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDS 240
                       E + +L E N+E++++  R  ++   L++      +E+ERL     D 
Sbjct: 480 IVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEE------KEQERL-----DI 528

Query: 241 HETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQL 300
            E   SL+ ++      +K V       K  +++ Q  +Q             +E+E  L
Sbjct: 529 EEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQ-------------REIEGLL 575

Query: 301 QSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEED 338
           ++  QL+  LR Q+ + ++ + R + +M+E      ED
Sbjct: 576 ENIRQLSRELRLQMLIIDNFIPRDYQEMIENYVHWNED 613



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 50/238 (21%), Positives = 94/238 (39%), Gaps = 30/238 (12%)

Query: 220 KDCLAEKAQEE-ERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQAR 278
           KD L  + Q+E E L ++L +  E   S  + S         V  +  K K+   + +  
Sbjct: 356 KDALLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVS 415

Query: 279 NQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERA---HGQMLE----- 330
              + E  A   +  K +E +L    +   + RA++   E +L +A   H  +LE     
Sbjct: 416 PDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSAL 475

Query: 331 ----------------EMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPA 374
                           E + L E+ N  +EE   RA+   + + E         L ++  
Sbjct: 476 EKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEK----EQERLDIEEK 531

Query: 375 LRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLR 432
             +L  +  G  ++++    +L  A +S  A++ Q  +       E +R+  REL+L+
Sbjct: 532 YTSLQEEAQGKTKKLKKVWTMLM-AAKSEMADLQQEHQREIEGLLENIRQLSRELRLQ 588


>gi|4758646 kinesin family member 3B [Homo sapiens]
          Length = 747

 Score =  239 bits (611), Expect = 6e-63
 Identities = 143/341 (41%), Positives = 207/341 (60%), Gaps = 18/341 (5%)

Query: 445 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGK----PVSFELDKVFSPQA 500
           ++RV+ R RP+  ++ +       V  D     +     KG     P +F  D V+   A
Sbjct: 9   SVRVVVRCRPMNGKE-KAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDWNA 67

Query: 501 SQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP---GINQRALQLLF 556
            Q +++ E  + LV S + GFN  IFAYGQTG GKTYTMEG   +P   G+   +   +F
Sbjct: 68  KQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIPNSFDHIF 127

Query: 557 SEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQV 616
           + +  ++ + +Y +  S  EIY E +RDLL K+  ++LE++  PD    +YV  L+ F  
Sbjct: 128 THIS-RSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTG--VYVKDLSSFVT 184

Query: 617 QSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVR----GVDCSTGLRTTGKLNL 672
           +SV +I  V   G+ NR+   TN+NEHSSRSHA+ ++T+     G+D    +R  GKLNL
Sbjct: 185 KSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRV-GKLNL 243

Query: 673 VDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL-RSRQGHVPFRNSKLTYLLQD 731
           VDLAGSER  K+GA+G RL+EA  IN SLSALG+VI+AL   +  H+P+R+SKLT LLQD
Sbjct: 244 VDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRLLQD 303

Query: 732 SLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGP 772
           SL G++KT+MV  V P   N  ETL +L++A R ++++  P
Sbjct: 304 SLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKP 344



 Score = 31.2 bits (69), Expect = 4.1
 Identities = 32/136 (23%), Positives = 62/136 (45%), Gaps = 11/136 (8%)

Query: 172 EHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEE 231
           E  ++   LR +    ++  A+ K M S+L +  +   D   E +      L +K QE  
Sbjct: 445 EKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQ----KILEQKRQEIA 500

Query: 232 RLSRRLRDSHETIASLRAQSPPVKYVIKT----VEVESSKTKQALSESQARNQH---LQE 284
              RR R+  + + S   ++  +K    +    V++++ K K+  S+ QA       LQE
Sbjct: 501 EQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQE 560

Query: 285 QVAMQRQVLKEMEQQL 300
           +   +RQ L++ + +L
Sbjct: 561 EHIKERQELEQTQNEL 576



 Score = 30.8 bits (68), Expect = 5.4
 Identities = 51/268 (19%), Positives = 110/268 (41%), Gaps = 64/268 (23%)

Query: 133 EKHRDLLMVENERLRQEMRRCEAELQ----------ELRTKPAGPCPGCEHSQESAQLRD 182
           E  +D L+ E    ++E+ R +A+L+          E R +  G   G E  +E  +  +
Sbjct: 348 EDPKDALLRE---FQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGE 404

Query: 183 ----------KLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEK------ 226
                     +  Q +LE+ E + ++ + +L  ++K   L E E +++D   EK      
Sbjct: 405 EEGDDKDDYWREQQEKLEI-EKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEML 463

Query: 227 -----AQEEERL-------------SRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKT 268
                A E + L              + L    + IA  + +   ++  +++ + E+ + 
Sbjct: 464 GAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLEL 523

Query: 269 KQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQM 328
           K+  S        LQ++V ++ + LK++  +LQ+       L+ +      ELE+   ++
Sbjct: 524 KETYSS-------LQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNEL 576

Query: 329 LEEMQSLE---------EDKNRAIEEAF 347
             E++            E+K++ +  AF
Sbjct: 577 TRELKLKHLIIENFIPLEEKSKIMNRAF 604


>gi|4758648 kinesin family member 5B [Homo sapiens]
          Length = 963

 Score =  222 bits (566), Expect = 1e-57
 Identities = 134/329 (40%), Positives = 201/329 (61%), Gaps = 14/329 (4%)

Query: 445 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQD 504
           NI+V+ R RP+ + +    +   A  F  +D  +I      KP +F  D+VF    SQ+ 
Sbjct: 8   NIKVMCRFRPLNESEVNRGDKYIA-KFQGEDTVVI----ASKPYAF--DRVFQSSTSQEQ 60

Query: 505 VFQE-VQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP---GINQRALQLLFSEVQ 560
           V+ +  + +V   ++G+N  IFAYGQT +GKT+TMEG   +P   GI  R +Q +F+ + 
Sbjct: 61  VYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIY 120

Query: 561 EKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVD 620
               + E+ I VS  EIY + +RDLL      K  + +  D +   YV G TE  V S D
Sbjct: 121 SMDENLEFHIKVSYFEIYLDKIRDLLDVS---KTNLSVHEDKNRVPYVKGCTERFVCSPD 177

Query: 621 DINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSER 680
           ++    + G +NR    TN+NEHSSRSH++ ++ V+  +  T  + +GKL LVDLAGSE+
Sbjct: 178 EVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEK 237

Query: 681 VGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTL 740
           V K+GAEG+ L EA++INKSLSALG+VI+AL     +VP+R+SK+T +LQDSL G+ +T 
Sbjct: 238 VSKTGAEGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNCRTT 297

Query: 741 MVVQVSPVEKNTSETLYSLKFAERVRSVE 769
           +V+  SP   N SET  +L F +R ++++
Sbjct: 298 IVICCSPSSYNESETKSTLLFGQRAKTIK 326



 Score = 34.3 bits (77), Expect = 0.49
 Identities = 43/214 (20%), Positives = 92/214 (42%), Gaps = 34/214 (15%)

Query: 118 QEVSRLRSELGG-----TDLEKHRDLLMVENERLRQEMRRCEAELQELRTKPAGPCPGCE 172
           +++S LR E+       TDL+     +M+E ERLR E  + +A                 
Sbjct: 714 KQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKAT---------------- 757

Query: 173 HSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEER 232
             QE ++   +L+ +Q    +++  L  L   V ++   L  +       LA + ++   
Sbjct: 758 -DQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAE 816

Query: 233 LSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSES---QARNQHLQEQVAMQ 289
           +     DS +T  S  AQ   + ++   +E  +   KQ + ++   +     L++++   
Sbjct: 817 I-----DSDDTGGS-AAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRAT 870

Query: 290 RQVLKEMEQQLQSSHQLTARLRAQIAMYESELER 323
            + +K +E  L+ + +  +R R +   Y+ E++R
Sbjct: 871 AERVKALESALKEAKENASRDRKR---YQQEVDR 901


>gi|41352705 kinesin family member 3C [Homo sapiens]
          Length = 793

 Score =  221 bits (564), Expect = 2e-57
 Identities = 143/365 (39%), Positives = 209/365 (57%), Gaps = 44/365 (12%)

Query: 446 IRVIARVRPVT-KEDGEGPEATNAVTFDADDDSIIHLLHKGKP----VSFELDKVFSPQA 500
           ++V+AR RP++ KE+  G E    +T D     +     +  P     +F  D V+   +
Sbjct: 11  LKVVARCRPLSRKEEAAGHE--QILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDASS 68

Query: 501 SQQDVFQE-VQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP---GINQRALQLLF 556
            Q D++ E V+ L+ S + GFN  +FAYGQTG GKTYTM+GT   P   G+   A + +F
Sbjct: 69  KQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPNAFEHIF 128

Query: 557 SEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQV 616
           + +  ++ + +Y +  S  EIY E +RDLL KEP ++LE++  P+    +Y+  L+ F  
Sbjct: 129 THIS-RSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETG--VYIKDLSSFVT 185

Query: 617 QSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTV----RGVDCSTGLRTTGKLNL 672
           ++V +I  V   G+  R    T++NE SSRSHA+ I+TV    RG D    +R  GKLNL
Sbjct: 186 KNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRV-GKLNL 244

Query: 673 VDLAGSERVGKSG------------------------AEGSRLREAQHINKSLSALGDVI 708
           VDLAGSER  K+G                        A G R +EA  IN SLSALG+VI
Sbjct: 245 VDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSALGNVI 304

Query: 709 AALR-SRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRS 767
           AAL  +R  H+P+R+SKLT LLQDSL G++KT+MV  + P   +  E+L +L+FA R ++
Sbjct: 305 AALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAKN 364

Query: 768 VELGP 772
           ++  P
Sbjct: 365 IKNKP 369



 Score = 38.9 bits (89), Expect = 0.020
 Identities = 54/257 (21%), Positives = 99/257 (38%), Gaps = 29/257 (11%)

Query: 218 RLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALS---- 273
           R K+   +    E+     LR+  E IA L+AQ      + K    +SS+ K+A+S    
Sbjct: 361 RAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPG 420

Query: 274 --------------ESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYES 319
                         E    N H   Q  ++  + K ME  LQ   +     +A I    S
Sbjct: 421 YPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRS 480

Query: 320 ELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLL----TLQPAL 375
            +     ++LEE + + ED  R  ++A      + KA+   L     N++      Q  L
Sbjct: 481 LVSEEKQKLLEEKEKMLEDLRRE-QQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKML 539

Query: 376 RTLTNDYNGLKRQVRGFP---LLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLR 432
                +    KR+ R      +L  E    ++       +EV    ++L + Y +   ++
Sbjct: 540 ELKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVK 599

Query: 433 KKC---HNELVRLKGNI 446
            +    H+E +R++ ++
Sbjct: 600 AEIQDQHDEYIRVRQDL 616



 Score = 38.9 bits (89), Expect = 0.020
 Identities = 55/270 (20%), Positives = 115/270 (42%), Gaps = 47/270 (17%)

Query: 107 EHLKEKLISQAQE-VSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRTKPA 165
           E  K+ L+ + QE ++RL+++L      + R +L    +R R++  R +  +      P 
Sbjct: 373 EDPKDTLLREFQEEIARLKAQL------EKRGML---GKRPRRKSSRRKKAVSAPPGYPE 423

Query: 166 GPCPGCEHSQESAQLRDKLSQLQ--LEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCL 223
           GP      ++E     +     Q  LE A  K M + L    Q++ +RL E +  ++D  
Sbjct: 424 GPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYL----QEQKERLEEEKAAIQDDR 479

Query: 224 AEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKT-------KQALSESQ 276
           +  ++E+++L   L +  + +  LR +    + +    +   SK            +E Q
Sbjct: 480 SLVSEEKQKL---LEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQ 536

Query: 277 ARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLR---------------------AQIA 315
              +  ++++A Q++  +EM+Q++    + T  LR                     A++ 
Sbjct: 537 KMLELKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQ 596

Query: 316 MYESELERAHGQMLEEMQSLEEDKNRAIEE 345
             ++E++  H + +   Q LEE +N    E
Sbjct: 597 AVKAEIQDQHDEYIRVRQDLEEAQNEQTRE 626


>gi|116686122 kinesin family member 4 [Homo sapiens]
          Length = 1232

 Score =  215 bits (548), Expect = 1e-55
 Identities = 144/341 (42%), Positives = 201/341 (58%), Gaps = 24/341 (7%)

Query: 446 IRVIARVRP-VTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQD 504
           +RV  R RP V KE  EG +    ++F   +  ++     G   SF  D VF P   Q++
Sbjct: 10  VRVALRCRPLVPKEISEGCQM--CLSFVPGEPQVV----VGTDKSFTYDFVFDPSTEQEE 63

Query: 505 VFQEVQA-LVTSCIDGFNVCIFAYGQTGAGKTYTMEG--TAENP-----GINQRALQLLF 556
           VF    A L+     G+N  + AYGQTG+GKTY+M G  TAE       G+  R +QLLF
Sbjct: 64  VFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLLF 123

Query: 557 SEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQV 616
            E+ +K SD+E+T+ VS  EIYNE + DLL    +EK +I +  D    + + GLTE  V
Sbjct: 124 KEIDKK-SDFEFTLKVSYLEIYNEEILDLLCPS-REKAQINIREDPKEGIKIVGLTEKTV 181

Query: 617 QSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTV---RGVDCSTGLRTTGKLNLV 673
               D     E G+ +RT   T +N  SSRSHA+  +++   +  D ++  R+  KL+LV
Sbjct: 182 LVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSFRS--KLHLV 239

Query: 674 DLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRS--RQGHVPFRNSKLTYLLQD 731
           DLAGSER  K+ AEG RL+E  +IN+ L  LG+VI+AL    + G VP+R+SKLT LLQD
Sbjct: 240 DLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQD 299

Query: 732 SLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGP 772
           SL G+S TLM+  VSP + N  ETL +L++A+R R ++  P
Sbjct: 300 SLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKP 340



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 72/351 (20%), Positives = 156/351 (44%), Gaps = 42/351 (11%)

Query: 105 QVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRTKP 164
           Q+  LK+KL  Q++ + +L+     T  + ++++ M++N+R+ Q MR+ + + ++ R   
Sbjct: 608 QIADLKKKLNEQSK-LLKLKESTERTVSKLNQEIRMMKNQRV-QLMRQMKEDAEKFRQWK 665

Query: 165 AGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCL- 223
                  +  +E  QL+++  + Q E+ + +    + +  +++KT+  A    RLKD L 
Sbjct: 666 Q------KKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQ 719

Query: 224 -----AEKAQEEE---------RLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTK 269
                A+K +E +         R+   L +  E + S       +  +++  ++ +    
Sbjct: 720 KQREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVA 779

Query: 270 QALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQML 329
           Q L E +   ++   ++  +   L E+  Q+  S      +  QI   E+E+E    Q+ 
Sbjct: 780 Q-LKEKKESGENPPPKLRRRTFSLTEVRGQVSESED---SITKQIESLETEMEFRSAQIA 835

Query: 330 EEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQV 389
           +  Q L +          A ++   K   EN+A     +L  + AL+ L  +    K QV
Sbjct: 836 DLQQKLLD----------AESEDRPKQRWENIA----TILEAKCALKYLIGELVSSKIQV 881

Query: 390 RGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELV 440
                 L+++  S  A++ + + E  ++  E+  + + EL   ++ H E V
Sbjct: 882 SKLESSLKQSKTSC-ADMQKMLFEERNHFAEIETELQAELVRMEQQHQEKV 931



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 39/190 (20%), Positives = 85/190 (44%), Gaps = 18/190 (9%)

Query: 179 QLRDKLSQLQLEMAESKGMLSELNLEVQ-------------QKTDRLAEVELRLKDCLAE 225
           Q +D + +L+LE+   +    EL LE+Q             ++  RL E+E ++ D L +
Sbjct: 556 QYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERRRKRLQELEGQIAD-LKK 614

Query: 226 KAQEEERLSRRLRDSHETIASLRAQSPPVK----YVIKTVEVESSKTKQALSESQARNQH 281
           K  E+ +L +    +  T++ L  +   +K     +++ ++ ++ K +Q   +       
Sbjct: 615 KLNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQ 674

Query: 282 LQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNR 341
           L+E+   ++  L ++E+  Q    +  R   + A     L+ A  +  E     +E ++R
Sbjct: 675 LKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSR 734

Query: 342 AIEEAFARAQ 351
            +E   AR +
Sbjct: 735 GMEGTAARVK 744



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 54/265 (20%), Positives = 125/265 (47%), Gaps = 40/265 (15%)

Query: 131  DLEKHRDLLMVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLE 190
            + ++H + L+ + + L Q++    A+L+E +     P P       S      L++++ +
Sbjct: 759  EAKRHLNDLLEDRKILAQDV----AQLKEKKESGENPPPKLRRRTFS------LTEVRGQ 808

Query: 191  MAESKGMLSE----LNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIAS 246
            ++ES+  +++    L  E++ ++ ++A+++ +L D     A+ E+R  +R     E IA+
Sbjct: 809  VSESEDSITKQIESLETEMEFRSAQIADLQQKLLD-----AESEDRPKQRW----ENIAT 859

Query: 247  LRAQSPPVKYVIKTV---EVESSKTKQALSESQA------------RNQHLQEQVAMQRQ 291
            +      +KY+I  +   +++ SK + +L +S+             RN   + +  +Q +
Sbjct: 860  ILEAKCALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQAE 919

Query: 292  VLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQ 351
            +++ MEQQ Q           Q  M E +LE +  +  +++ S  + ++  +E+     +
Sbjct: 920  LVR-MEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEELEKMREVCE 978

Query: 352  VEMKAVHENLAGVRTNLLTLQPALR 376
               + + EN   ++  L  LQ A R
Sbjct: 979  QNQQLLRENEI-IKQKLTLLQVASR 1002


>gi|170784809 kinesin family member 17 isoform b [Homo sapiens]
          Length = 1028

 Score =  215 bits (548), Expect = 1e-55
 Identities = 154/398 (38%), Positives = 221/398 (55%), Gaps = 28/398 (7%)

Query: 446 IRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGK----PVSFELDKVFSPQAS 501
           ++V+ R RP+ + + E       VT D        + + G     P  F  D  +     
Sbjct: 6   VKVVVRCRPMNQRERE-LRCQPVVTVDCARAQCC-IQNPGAADEPPKQFTFDGAYHVDHV 63

Query: 502 QQDVFQEVQ-ALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP---GINQRALQLLFS 557
            + ++ E+   LV    +G+N  IFAYGQTG+GK++TM+G  + P   GI  RA + +F 
Sbjct: 64  TEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQRGIIPRAFEHVFE 123

Query: 558 EVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQ 617
            VQ  A + ++ +  S  EIYNE +RDLLG + ++KLE++  P+    +YV GL+   V 
Sbjct: 124 SVQ-CAENTKFLVRASYLEIYNEDVRDLLGADTKQKLELKEHPEKG--VYVKGLSMHTVH 180

Query: 618 SVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTV-------RGVDCSTGLRTTGKL 670
           SV     + E G  NR+  +T +N+ SSRSH++  +++       RG D    LR  GKL
Sbjct: 181 SVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKD---HLRA-GKL 236

Query: 671 NLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL-RSRQGHVPFRNSKLTYLL 729
           NLVDLAGSER  K+GA G RL+EA  IN SLSALG+VI+AL   R  HVP+R+SKLT LL
Sbjct: 237 NLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHVPYRDSKLTRLL 296

Query: 730 QDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELGSW--SSQEH 787
           QDSL G++KTLMV  +SP + N  ETL +L++A R +++   P +      +     QE 
Sbjct: 297 QDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDPKDALLREYQEE 356

Query: 788 LEWEPACQTPQPSARAHSA-PSSGTSSRPGSIRRKLQP 824
           ++   A  T Q S  + SA  S      P  +  KL P
Sbjct: 357 IKKLKAILTQQMSPSSLSALLSRQVPPDPVQVEEKLLP 394


>gi|170784807 kinesin family member 17 isoform a [Homo sapiens]
          Length = 1029

 Score =  215 bits (548), Expect = 1e-55
 Identities = 154/398 (38%), Positives = 221/398 (55%), Gaps = 28/398 (7%)

Query: 446 IRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGK----PVSFELDKVFSPQAS 501
           ++V+ R RP+ + + E       VT D        + + G     P  F  D  +     
Sbjct: 6   VKVVVRCRPMNQRERE-LRCQPVVTVDCARAQCC-IQNPGAADEPPKQFTFDGAYHVDHV 63

Query: 502 QQDVFQEVQ-ALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP---GINQRALQLLFS 557
            + ++ E+   LV    +G+N  IFAYGQTG+GK++TM+G  + P   GI  RA + +F 
Sbjct: 64  TEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQRGIIPRAFEHVFE 123

Query: 558 EVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQ 617
            VQ  A + ++ +  S  EIYNE +RDLLG + ++KLE++  P+    +YV GL+   V 
Sbjct: 124 SVQ-CAENTKFLVRASYLEIYNEDVRDLLGADTKQKLELKEHPEKG--VYVKGLSMHTVH 180

Query: 618 SVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTV-------RGVDCSTGLRTTGKL 670
           SV     + E G  NR+  +T +N+ SSRSH++  +++       RG D    LR  GKL
Sbjct: 181 SVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKD---HLRA-GKL 236

Query: 671 NLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL-RSRQGHVPFRNSKLTYLL 729
           NLVDLAGSER  K+GA G RL+EA  IN SLSALG+VI+AL   R  HVP+R+SKLT LL
Sbjct: 237 NLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHVPYRDSKLTRLL 296

Query: 730 QDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELGSW--SSQEH 787
           QDSL G++KTLMV  +SP + N  ETL +L++A R +++   P +      +     QE 
Sbjct: 297 QDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINEDPKDALLREYQEE 356

Query: 788 LEWEPACQTPQPSARAHSA-PSSGTSSRPGSIRRKLQP 824
           ++   A  T Q S  + SA  S      P  +  KL P
Sbjct: 357 IKKLKAILTQQMSPSSLSALLSRQVPPDPVQVEEKLLP 394


>gi|150010604 kinesin family member 4B [Homo sapiens]
          Length = 1234

 Score =  213 bits (542), Expect = 6e-55
 Identities = 144/341 (42%), Positives = 200/341 (58%), Gaps = 24/341 (7%)

Query: 446 IRVIARVRP-VTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQD 504
           +RV  R RP V KE  EG +    ++F   +  ++     G   SF  D VF P   Q++
Sbjct: 10  VRVALRCRPLVPKEISEGCQM--CLSFVPGETQVV----VGTDKSFTYDFVFDPCTEQEE 63

Query: 505 VFQEVQA-LVTSCIDGFNVCIFAYGQTGAGKTYTMEG--TAENP-----GINQRALQLLF 556
           VF +  A L+     G+N  + AYGQTG+GKTY+M G  TAE       GI  R +QLLF
Sbjct: 64  VFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQLLF 123

Query: 557 SEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQV 616
            E+ +K SD+E+T+ VS  EIYNE + DLL    +EK +I +  D    + + GLTE  V
Sbjct: 124 KEIDKK-SDFEFTLKVSYLEIYNEEILDLLCPS-REKAQINIREDPKEGIKIVGLTEKTV 181

Query: 617 QSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTV---RGVDCSTGLRTTGKLNLV 673
               D     E G+ +RT   T +N  SSRSHA+  +++   +  D +   R+  KL+LV
Sbjct: 182 LVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDKNCSFRS--KLHLV 239

Query: 674 DLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRS--RQGHVPFRNSKLTYLLQD 731
           DLAGSER  K+ AEG RL+E  +IN+ L  LG+VI+AL    +   VP+R+SKLT LLQD
Sbjct: 240 DLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGSFVPYRDSKLTRLLQD 299

Query: 732 SLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGP 772
           SL G+S TLM+  VSP + N  ETL +L++A+R R ++  P
Sbjct: 300 SLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKP 340



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 73/351 (20%), Positives = 161/351 (45%), Gaps = 42/351 (11%)

Query: 105 QVEHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRTKP 164
           Q+  LK+KL  Q++ + +L+     T  + ++++ M++N+R+ Q MR+ + + ++ R   
Sbjct: 608 QIADLKKKLNEQSK-LLKLKESTERTVSKLNQEIWMMKNQRV-QLMRQMKEDAEKFRQWK 665

Query: 165 AGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLA 224
                  +  +E  QL+++  + Q E+ + +    + +  +++KT+  A    RLKD L 
Sbjct: 666 Q------KKDKEVIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDALQ 719

Query: 225 EKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQE 284
           ++ +  ++         E IA+ R ++    ++   +EV        +  ++   +HL +
Sbjct: 720 KQREVTDKRKETQSHGKEGIAA-RVRN----WLGNEIEV--------MVSTEEAKRHLND 766

Query: 285 QVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLE-------EMQSLE- 336
            +   R++L +   QL+   +       ++      L   HGQ+LE       +++SLE 
Sbjct: 767 -LLEDRKILAQDVVQLKEKKESRENPPPKLRKCTFSLSEVHGQVLESEDCITKQIESLET 825

Query: 337 EDKNRAIEEA-------FARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQV 389
           E + R+ + A        A ++   K   EN+A     +L  + AL+ L  +    K  V
Sbjct: 826 EMELRSAQIADLQQKLLDAESEDRPKQCWENIA----TILEAKCALKYLIGELVSSKIHV 881

Query: 390 RGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELV 440
                 L+++  S  A++ + + E  ++  E+  + + EL   ++ H E V
Sbjct: 882 TKLENSLRQSKASC-ADMQKMLFEEQNHFSEIETELQAELVRMEQQHQEKV 931



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 54/271 (19%), Positives = 122/271 (45%), Gaps = 40/271 (14%)

Query: 131  DLEKHRDLLMVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLE 190
            + ++H + L+ + + L Q++ + + E +E R  P      C  S         LS++  +
Sbjct: 759  EAKRHLNDLLEDRKILAQDVVQLK-EKKESRENPPPKLRKCTFS---------LSEVHGQ 808

Query: 191  MAESKGMLSE----LNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIAS 246
            + ES+  +++    L  E++ ++ ++A+++ +L D  +E          R +   E IA+
Sbjct: 809  VLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESED---------RPKQCWENIAT 859

Query: 247  LRAQSPPVKYVIKTV---EVESSKTKQALSESQARNQHLQEQVAMQRQVLKE-------- 295
            +      +KY+I  +   ++  +K + +L +S+A    +Q+ +  ++    E        
Sbjct: 860  ILEAKCALKYLIGELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIETELQAE 919

Query: 296  ---MEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQV 352
               MEQQ Q           +  M E +LE++  +  +++ S  + ++  +E+     + 
Sbjct: 920  LVRMEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLVSTLQCQDEELEKMREVCEQ 979

Query: 353  EMKAVHENLAGVRTNLLTLQPALRT--LTND 381
              + + EN   ++  L+ LQ A R   L ND
Sbjct: 980  NQQLLQENEI-IKQKLILLQVASRQKHLPND 1009


>gi|4758650 kinesin family member 5C [Homo sapiens]
          Length = 957

 Score =  213 bits (542), Expect = 6e-55
 Identities = 129/330 (39%), Positives = 199/330 (60%), Gaps = 14/330 (4%)

Query: 445 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQD 504
           +I+V+ R RP+   + E       +     D++++  + +GKP  F  D+V  P  +Q+ 
Sbjct: 8   SIKVMCRFRPLN--EAEILRGDKFIPKFKGDETVV--IGQGKPYVF--DRVLPPNTTQEQ 61

Query: 505 VFQE-VQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP---GINQRALQLLFSEVQ 560
           V+    + +V   ++G+N  IFAYGQT +GKT+TMEG   +P   GI  R    +F  + 
Sbjct: 62  VYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIY 121

Query: 561 EKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVD 620
               + E+ I VS  EIY + +RDLL      K  + +  D +   YV G TE  V S +
Sbjct: 122 SMDENLEFHIKVSYFEIYLDKIRDLLDVS---KTNLAVHEDKNRVPYVKGCTERFVSSPE 178

Query: 621 DINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSER 680
           ++  V + G  NR    TN+NEHSSRSH++ ++ ++  +  T  + +GKL LVDLAGSE+
Sbjct: 179 EVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEK 238

Query: 681 VGKSGAEGSRLREAQHINKSLSALGDVIAAL-RSRQGHVPFRNSKLTYLLQDSLSGDSKT 739
           V K+GAEG+ L EA++INKSLSALG+VI+AL    + HVP+R+SK+T +LQDSL G+ +T
Sbjct: 239 VSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRT 298

Query: 740 LMVVQVSPVEKNTSETLYSLKFAERVRSVE 769
            +V+  SP   N +ET  +L F +R ++++
Sbjct: 299 TIVICCSPSVFNEAETKSTLMFGQRAKTIK 328



 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 84/363 (23%), Positives = 151/363 (41%), Gaps = 44/363 (12%)

Query: 107 EHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRTKPAG 166
           E LK++++ Q + ++  R +      E  R  L +ENE  + E++     L+EL      
Sbjct: 443 EKLKQQMLDQDELLASTRRDYEKIQEELTR--LQIENEAAKDEVKEVLQALEELAVNYDQ 500

Query: 167 PCPGCEH-SQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEV-ELRLKDC-- 222
                E  ++ + QL D+L+Q    +  ++  LS+L      +  R  E+  L LKD   
Sbjct: 501 KSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGE 560

Query: 223 ------------LAEK--AQEEERLSRRLRDSH--ETIASLRAQSPPVKYV-------IK 259
                       LA+     EEE    RL  S     + SL  +S  ++         + 
Sbjct: 561 IGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMN 620

Query: 260 TVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYES 319
             E E +  +  +S+ +A+ + L + +    Q  +++E+   S  +  A+LRAQ  M+E 
Sbjct: 621 ASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEV 680

Query: 320 ELERAHGQMLEEMQSLEEDK----------NRAIEEAFARAQVEMKAVHENLAGVRTNLL 369
             +    + L  +Q  EE K            A ++  +R + E++   + +  +R    
Sbjct: 681 SFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIEEKQKIIDEIRDLNQ 740

Query: 370 TLQPALRTLTNDYNGLK-----RQVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRK 424
            LQ     L++DYN LK     R+++   LLL    R    E  + +EE  S   + L  
Sbjct: 741 KLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHN 800

Query: 425 YRR 427
            R+
Sbjct: 801 LRK 803


>gi|45446749 kinesin family member 5A [Homo sapiens]
          Length = 1032

 Score =  213 bits (542), Expect = 6e-55
 Identities = 131/330 (39%), Positives = 199/330 (60%), Gaps = 15/330 (4%)

Query: 445 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQD 504
           +I+V+ R RP+ + +    +    + F  DD  +I     GKP  F  D+VF P  +Q+ 
Sbjct: 9   SIKVLCRFRPLNQAEILRGDKFIPI-FQGDDSVVIG----GKPYVF--DRVFPPNTTQEQ 61

Query: 505 VFQE-VQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP---GINQRALQLLFSEVQ 560
           V+      +V   + G+N  IFAYGQT +GKT+TMEG   +P   GI  R  + +F+ + 
Sbjct: 62  VYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHIY 121

Query: 561 EKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVD 620
               + E+ I VS  EIY + +RDLL      K  + +  D +   +V G TE  V S +
Sbjct: 122 SMDENLEFHIKVSYFEIYLDKIRDLLDVT---KTNLSVHEDKNRVPFVKGCTERFVSSPE 178

Query: 621 DINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSER 680
           +I  V + G +NR    TN+NEHSSRSH++ ++ ++  +  T  + +GKL LVDLAGSE+
Sbjct: 179 EILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQKLSGKLYLVDLAGSEK 238

Query: 681 VGKSGAEGSRLREAQHINKSLSALGDVIAAL-RSRQGHVPFRNSKLTYLLQDSLSGDSKT 739
           V K+GAEG+ L EA++INKSLSALG+VI+AL    + +VP+R+SK+T +LQDSL G+ +T
Sbjct: 239 VSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQDSLGGNCRT 298

Query: 740 LMVVQVSPVEKNTSETLYSLKFAERVRSVE 769
            M +  SP   N +ET  +L F +R ++++
Sbjct: 299 TMFICCSPSSYNDAETKSTLMFGQRAKTIK 328



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 56/290 (19%), Positives = 124/290 (42%), Gaps = 42/290 (14%)

Query: 186 QLQLEMAESKGMLSELNLEVQQKTDRLAEVEL-RLKDCLAEKAQEEERLSRRLRDSHETI 244
           +L  E  + K    +   + Q++T    E EL R ++   E   E ERL+         +
Sbjct: 336 ELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRN--GENVPETERLA----GEEAAL 389

Query: 245 ASLRAQSPPVK----YVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQL 300
            +   +  PV      V++    E  K ++ +     +     +++  Q Q++++++QQ+
Sbjct: 390 GAELCEETPVNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQM 449

Query: 301 QSSHQLTARLRA-------QIAMYESELERAHGQMLEEMQSLEE------DKNRAIEEAF 347
               +L    R        +++  +SE + A  ++ E +Q+LEE       K++ +EE  
Sbjct: 450 LDQEELLVSTRGDNEKVQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKS 509

Query: 348 ARAQVEMKAVHENLA---GVRTNLLTLQPAL----RTLTNDYNGLKRQVRGFPLLLQEAL 400
            + Q+ +  + + +A    + + L  LQ       + +    NGL + +  F +++    
Sbjct: 510 QQNQLLVDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGE 569

Query: 401 RSVKAEIGQAIEE-----------VNSNNQELLRKYRRELQLRKKCHNEL 439
             +  EI  AIEE           + S  + ++++ R+   L+ +CH ++
Sbjct: 570 IKLPVEISGAIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKM 619



 Score = 38.9 bits (89), Expect = 0.020
 Identities = 52/271 (19%), Positives = 116/271 (42%), Gaps = 29/271 (10%)

Query: 107 EHLKEKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRTKPAG 166
           E  KEK  +Q + +++L +EL      ++    + E ERL  E     AEL E       
Sbjct: 347 EKEKEKTKAQKETIAKLEAELSRWRNGEN----VPETERLAGEEAALGAELCE------- 395

Query: 167 PCPGCEHSQESAQLR-DKLSQLQLEMAESKGMLSELNLEVQQKT---DRLAEVELRLKDC 222
             P  ++S    ++  ++  + + E+      L + + E+ Q++   ++L +  L  ++ 
Sbjct: 396 ETPVNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEEL 455

Query: 223 LAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHL 282
           L     + E++ R L        + + +   V   ++ + V   +  Q + E   +NQ L
Sbjct: 456 LVSTRGDNEKVQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLL 515

Query: 283 QEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIA---------MYESELERAHGQMLEEMQ 333
            ++++ +   +  +E +LQ   +++   R +IA         + E  +   +G++     
Sbjct: 516 VDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEI----- 570

Query: 334 SLEEDKNRAIEEAFARAQVEMKAVHENLAGV 364
            L  + + AIEE F  A++ +  +   +  V
Sbjct: 571 KLPVEISGAIEEEFTVARLYISKIKSEVKSV 601



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 54/260 (20%), Positives = 109/260 (41%), Gaps = 33/260 (12%)

Query: 104 LQVEHLKEKLISQAQEVSRLRS------------ELGGTDLEKHRDLLMVENERLRQEMR 151
           L+  HL+E   S + E+++L++            E    D ++ +  L ++ E  R+   
Sbjct: 652 LKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKALELQMESHREAHH 711

Query: 152 RCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDR 211
           R  A L++            E  +   +L+D   +LQLE+ + +    +L  E  +K+ +
Sbjct: 712 RQLARLRDEIN---------EKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTK 762

Query: 212 LAEVEL---RLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKT 268
           L E+     R +    +    EE ++R L+  H  +  L  Q    + V K+ E+E   +
Sbjct: 763 LQELTFLYERHEQSKQDLKGLEETVARELQTLH-NLRKLFVQDVTTR-VKKSAEMEPEDS 820

Query: 269 KQALSESQA---RNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAH 325
               S+ Q       +L++   + +Q++++         +L  RLRA        ++   
Sbjct: 821 GGIHSQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRAT----AERVKALE 876

Query: 326 GQMLEEMQSLEEDKNRAIEE 345
           G + E  +   +DK R  +E
Sbjct: 877 GALKEAKEGAMKDKRRYQQE 896


>gi|46852172 kinesin family member 13B [Homo sapiens]
          Length = 1826

 Score =  212 bits (539), Expect = 1e-54
 Identities = 139/354 (39%), Positives = 201/354 (56%), Gaps = 37/354 (10%)

Query: 446 IRVIARVRPVTKEDGEGPEA------TNAVTFDADDDSIIHLLHKGKPVSFELDKVF--- 496
           ++V  R+RP+ + + +           N V  +  + ++     +G+P  F  D  F   
Sbjct: 6   VKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDHCFWSM 65

Query: 497 -----SPQASQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQR 550
                   A Q  VF+ + + ++ +  DG+N CIFAYGQTG+GK+YTM GTA+ PG+  R
Sbjct: 66  DESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQPGLIPR 125

Query: 551 ALQLLFSEVQ-EKASDWEYTITVSAAEIYNEVLRDLLG-KEPQEKLEIR----LCPDGSG 604
               LF   Q E+  +  + + VS  EIYNE +RDLL  K  ++ L++R    L P    
Sbjct: 126 LCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLGP---- 181

Query: 605 QLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVR----GVDC 660
             YV GL++  V S  DI  +   G+ +RT   TN+NE SSRSHA+  +T+      V  
Sbjct: 182 --YVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKS 239

Query: 661 STGLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL------RSR 714
            T     GKL+LVDLAGSER  K+GA G RL+E  +INKSL+ LG VI+AL      +++
Sbjct: 240 GTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNK 299

Query: 715 QGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSV 768
              VP+R+S LT+LL+DSL G+SKT MV  VSP   N  ETL +L++A+R + +
Sbjct: 300 NKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHI 353



 Score = 30.4 bits (67), Expect = 7.1
 Identities = 31/147 (21%), Positives = 58/147 (39%), Gaps = 25/147 (17%)

Query: 261 VEVESSKTKQALSESQARNQHLQEQVAMQ--------RQVLKEMEQQLQSSHQLTARLRA 312
           ++V+   + +  SE     ++ Q +V M+        + +L  +EQQ +   +  + L  
Sbjct: 571 LDVDGDSSSEVSSEVNFNYEYAQMEVTMKALGSNDPMQSILNSLEQQHEEEKR--SALER 628

Query: 313 QIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQ 372
           Q  MYE ELE+   ++  E Q+       +     A+ ++   A                
Sbjct: 629 QRLMYEHELEQLRRRLSPEKQNCRSMDRFSFHSPSAQQRLRQWAEERE------------ 676

Query: 373 PALRTLTNDYNGLKRQVRGFPLLLQEA 399
               TL N    L+ Q+    LL++EA
Sbjct: 677 ---ATLNNSLMRLREQIVKANLLVREA 700


>gi|40254834 kinesin family member 1C [Homo sapiens]
          Length = 1103

 Score =  208 bits (529), Expect = 2e-53
 Identities = 157/413 (38%), Positives = 226/413 (54%), Gaps = 30/413 (7%)

Query: 445 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLH-KGKPVSFELDKVF------- 496
           +++V  RVRP    +    +A   V+   +  SII+    K  P SF  D  +       
Sbjct: 5   SVKVAVRVRPFNARE-TSQDAKCVVSMQGNTTSIINPKQSKDAPKSFTFDYSYWSHTSTE 63

Query: 497 SPQ-ASQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAE--NPGINQRAL 552
            PQ ASQQ V++++ + ++    +G+NVCIFAYGQTGAGK+YTM G  E    GI  +  
Sbjct: 64  DPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGRQEPGQQGIVPQLC 123

Query: 553 QLLFSEVQEKAS-DWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGL 611
           + LFS V E  S    Y++ VS  EIY E +RDLL  + +  L +R  P      YV  L
Sbjct: 124 EDLFSRVSENQSAQLSYSVEVSYMEIYCERVRDLLNPKSRGSLRVREHPILGP--YVQDL 181

Query: 612 TEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHAL--LIVTVRGVDCSTGLRT--T 667
           ++  V S  DI  + + G+  RT   TN+NE SSRSHA+  ++ T R  D  TGL +   
Sbjct: 182 SKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQRCHDQLTGLDSEKV 241

Query: 668 GKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQG------HVPFR 721
            K++LVDLAGSER   SGA G RL+E  +INKSL+ LG VI+AL   Q        +P+R
Sbjct: 242 SKISLVDLAGSERADSSGARGMRLKEGANINKSLTTLGKVISALADMQSKKRKSDFIPYR 301

Query: 722 NSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGPGLRRAELGS 781
           +S LT+LL+++L G+S+T M+  +SP + N  ETL +L++A+R + +     +   E  +
Sbjct: 302 DSVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYADRTKQIRCNAIIN--EDPN 359

Query: 782 WSSQEHLEWEPACQTPQPSARAHSAPS-SGTSSRPGSIRRKLQPSGKSRPLPV 833
                 L+ E A       A+  SA +  G  +  GS+R  L P+  S P PV
Sbjct: 360 ARLIRELQEEVARLRELLMAQGLSASALEGLKTEEGSVRGAL-PAVSSPPAPV 411



 Score = 34.3 bits (77), Expect = 0.49
 Identities = 42/188 (22%), Positives = 81/188 (43%), Gaps = 15/188 (7%)

Query: 154 EAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMA-ESKGMLSELNLEVQQKTDRL 212
           +A L+  R  P  P P  E    +   ++ L Q  +++  E +  L +L  + +++ +  
Sbjct: 602 QARLERERGVPPPPGPPSEPVDWNFAQKELLEQQGIDIKLEMEKRLQDLENQYRKEKEE- 660

Query: 213 AEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQSPP--VKYVIKTVEVESSKTKQ 270
           A++ L  +   A+    ++   R   +S   I+SLR Q PP  V+ ++K   + SS  ++
Sbjct: 661 ADLLLEQQRLYADSDSGDDSDKRSCEESWRLISSLREQLPPTTVQTIVKRCGLPSSGKRR 720

Query: 271 A---------LSESQARNQHLQEQVAMQRQVLKEM--EQQLQSSHQLTARLRAQIAMYES 319
           A             Q ++        ++ Q +KE+  E  L       A + A  A+   
Sbjct: 721 APRRVYQIPQRRRLQGKDPRWATMADLKMQAVKEICYEVALADFRHGRAEIEALAALKMR 780

Query: 320 ELERAHGQ 327
           EL R +G+
Sbjct: 781 ELCRTYGK 788


>gi|13699824 kinesin family member 11 [Homo sapiens]
          Length = 1056

 Score =  203 bits (516), Expect = 6e-52
 Identities = 133/345 (38%), Positives = 191/345 (55%), Gaps = 24/345 (6%)

Query: 445 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSII----HLLHKGKPVSFELDKVFSPQA 500
           NI+V+ R RP    + +   A + V  D     +      L  K    ++  D VF    
Sbjct: 18  NIQVVVRCRPFNLAERKA-SAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGAST 76

Query: 501 SQQDVFQEVQA-LVTSCIDGFNVCIFAYGQTGAGKTYTMEGTA---------ENP--GIN 548
            Q DV++ V   ++   I G+N  IFAYGQTG GKT+TMEG           E+P  GI 
Sbjct: 77  KQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGII 136

Query: 549 QRALQLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLG--KEPQEKLEIRLCPDGSGQL 606
            R L  +F ++ +  +  E+++ VS  EIYNE L DLL    +  E+L++   P     +
Sbjct: 137 PRTLHQIFEKLTDNGT--EFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGV 194

Query: 607 YVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTG--- 663
            + GL E  V + D++ ++ E G   RTT  T +N +SSRSH++  VT+   + +     
Sbjct: 195 IIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEE 254

Query: 664 LRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNS 723
           L   GKLNLVDLAGSE +G+SGA   R REA +IN+SL  LG VI AL  R  HVP+R S
Sbjct: 255 LVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVERTPHVPYRES 314

Query: 724 KLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSV 768
           KLT +LQDSL G ++T ++  +SP   N  ETL +L++A R +++
Sbjct: 315 KLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNI 359



 Score = 30.8 bits (68), Expect = 5.4
 Identities = 48/250 (19%), Positives = 104/250 (41%), Gaps = 37/250 (14%)

Query: 174 SQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERL 233
           S   +Q+ + + + Q   AESK +L EL   +  KTD L+ +E+ L              
Sbjct: 597 STHVSQIFNMILKEQSLAAESKTVLQELINVL--KTDLLSSLEMILSP------------ 642

Query: 234 SRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQV-AMQRQV 292
                    T+ S+   +  +K++ KT    + K +    E       L   +  +Q   
Sbjct: 643 ---------TVVSILKINSQLKHIFKTSLTVADKIEDQKKELDGFLSILCNNLHELQENT 693

Query: 293 LKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQV 352
           +  + +  +    LT  L+         +++ H Q L ++ +L  ++  A+EE     Q 
Sbjct: 694 ICSLVESQKQCGNLTEDLKT--------IKQTHSQELCKLMNLWTERFCALEEKCENIQK 745

Query: 353 EMKAVHENLAGVRTNLLT-LQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQAI 411
            + +V EN+     +++  +    +    D +G  +++R F    QE  + V+  +  + 
Sbjct: 746 PLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFSQELRNFN---QEGTKLVEESVKHS- 801

Query: 412 EEVNSNNQEL 421
           +++N N +++
Sbjct: 802 DKLNGNLEKI 811


>gi|122937289 kinesin family member 18B [Homo sapiens]
          Length = 855

 Score =  203 bits (516), Expect = 6e-52
 Identities = 119/294 (40%), Positives = 178/294 (60%), Gaps = 11/294 (3%)

Query: 484 KGKPVSFELDKVFSPQASQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTA 542
           KGK ++F  D+VF   A+QQDVFQ    +++ S + G+N  +FAYG TGAGKT+TM G  
Sbjct: 64  KGKDLTFVFDRVFGEAATQQDVFQHTTHSVLDSFLQGYNCSVFAYGATGAGKTHTMLGRE 123

Query: 543 ENPGINQRALQLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDG 602
            +PGI       L+  ++ +  +  + + +S  E+YNE + DLL  EP+  L IR  PD 
Sbjct: 124 GDPGIMYLTTVELYRRLEARQQEKHFEVLISYQEVYNEQIHDLL--EPKGPLAIREDPDK 181

Query: 603 SGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCST 662
              + V GL+  Q  S + + ++   G+ NRT   T+ N  SSRSHA+  + V+  D   
Sbjct: 182 G--VVVQGLSFHQPASAEQLLEILTRGNRNRTQHPTDANATSSRSHAIFQIFVKQQDRVP 239

Query: 663 GLR---TTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL---RSRQG 716
           GL       K++L+DLAGSER   + A+G RLRE  +IN+SL AL +V+ AL   + R+ 
Sbjct: 240 GLTQAVQVAKMSLIDLAGSERASSTHAKGERLREGANINRSLLALINVLNALADAKGRKT 299

Query: 717 HVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVEL 770
           HVP+R+SKLT LL+DSL G+ +T+M+  +SP      +T  +LK+A+R + + L
Sbjct: 300 HVPYRDSKLTRLLKDSLGGNCRTVMIAAISPSSLTYEDTYNTLKYADRAKEIRL 353


>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
          Length = 1317

 Score =  202 bits (514), Expect = 1e-51
 Identities = 130/358 (36%), Positives = 203/358 (56%), Gaps = 36/358 (10%)

Query: 445 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLL---------HKGKPVSFELDKV 495
           +++V  RVRP+ + + +  EA   +  +    +I +L           + +  +F  D  
Sbjct: 3   SVKVAVRVRPMNRREKD-LEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFS 61

Query: 496 F------SPQ-ASQQDVFQEVQA-LVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGI 547
           F      SP   SQ+ VF+ +   +V S  +G+N C+FAYGQTG+GK+YTM G + + G+
Sbjct: 62  FYSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDSGL 121

Query: 548 NQRALQLLFSEVQEKASDWE---YTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSG 604
             R  + LFS + E  + W+   +   VS  EIYNE +RDLL ++  +   +R+      
Sbjct: 122 IPRICEGLFSRINE-TTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKE 180

Query: 605 QLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIV--TVRGVDCST 662
             YV  L++  VQ+  D+ ++ + G+ NRTT  T +N+ SSRSHA+  +  T    D   
Sbjct: 181 GPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSEM 240

Query: 663 GLRTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL----------- 711
              T  K++LVDLAGSER   +GA G RL+E  +INKSL  LG+VI+AL           
Sbjct: 241 PCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAANTL 300

Query: 712 -RSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSV 768
            + +Q  VP+R+S LT+LL+DSL G+SKT+M+  +SP + N  ETL +L++A R +++
Sbjct: 301 AKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNI 358



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 70/339 (20%), Positives = 140/339 (41%), Gaps = 33/339 (9%)

Query: 173 HSQESAQLRDKLSQLQLEMAESKGMLSELNL---EVQQKTDRLAEVELRLKDCLAEKAQE 229
           H +E+A+LR+K            G+LS  +L   ++ +  + L+ V L       E+ Q 
Sbjct: 553 HPKEAAKLREK---------RKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQR 603

Query: 230 EERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQ 289
           EE          E + S R     ++   K+ + E  + +Q +   +   + +Q Q+  Q
Sbjct: 604 EEL---------EKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQ 654

Query: 290 RQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFAR 349
            + LK      + S  +  +L+  +A    E E+   + L E Q +E  K R  EE F R
Sbjct: 655 EESLK------RRSFHIENKLKDLLA----EKEKFEEERLREQQEIELQKKRQEEETFLR 704

Query: 350 AQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVKAEIGQ 409
            Q E++ + E     +     +   L  L  + +    ++      L+E  +     +  
Sbjct: 705 VQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAH 764

Query: 410 AIEEVNSNNQELLRKYRR-ELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNA 468
            +EE     QE+++  RR E+Q  ++   +L  ++ ++  +   R    EDGE  E    
Sbjct: 765 -LEEQLREKQEMIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQL 823

Query: 469 VTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQDVFQ 507
             F+     ++ L++  K +  + D +      +Q++ +
Sbjct: 824 RFFEFKRRQLVKLVNLEKDLVQQKDILKKEVQEEQEILE 862



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 82/317 (25%), Positives = 137/317 (43%), Gaps = 47/317 (14%)

Query: 108 HLKEKLISQAQEVSRLRSE--LGGTDLEKHRDLL---MVENERLRQEMRRCEAELQELRT 162
           H KE    + +  S L S   L  TDL K R+ L   M+ N  L  E ++ E EL++L +
Sbjct: 553 HPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQRE-ELEKLES 611

Query: 163 KPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKT--DRLAEVELRLK 220
           K        E  Q+S +   +  Q ++E    +  + +L +  Q+++   R   +E +LK
Sbjct: 612 KRK-LIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLK 670

Query: 221 DCLAEKAQ-EEERLS-------RRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQAL 272
           D LAEK + EEERL        ++ R   ET   ++ +   +K +    + E  +  Q L
Sbjct: 671 DLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQEL 730

Query: 273 SESQARNQHLQEQVAMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLE-- 330
            + Q   +   EQ A      K +E+Q +    L A L  Q+   +  +     Q+L   
Sbjct: 731 DQLQ---KEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMI-----QLLRRG 782

Query: 331 EMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGL-KRQV 389
           E+Q +EE+K                    +L G+R +LL ++ A      D   L K Q+
Sbjct: 783 EVQWVEEEK-------------------RDLEGIRESLLRVKEARAGGDEDGEELEKAQL 823

Query: 390 RGFPLLLQEALRSVKAE 406
           R F    ++ ++ V  E
Sbjct: 824 RFFEFKRRQLVKLVNLE 840


>gi|156616271 kinesin family member 19 [Homo sapiens]
          Length = 998

 Score =  201 bits (511), Expect = 2e-51
 Identities = 124/341 (36%), Positives = 193/341 (56%), Gaps = 22/341 (6%)

Query: 446 IRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHL-----------LHKGKPVSFELDK 494
           + V  RVRP++  + E  E    +    D+  ++ +            H+ +  S+  D 
Sbjct: 12  LMVALRVRPISVAELE--EGATLIAHKVDEQMVVLMDPMEDPDDILRAHRSREKSYLFDV 69

Query: 495 VFSPQASQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQ 553
            F   A+Q+ V+Q   ++L+   I G+N  +FAYG TG GKTYTM GT + PGI  + L 
Sbjct: 70  AFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGTDQEPGIYVQTLN 129

Query: 554 LLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTE 613
            LF  ++E ++D EY +++S  EIYNE++RDLL       LE+R   D  G + V G+TE
Sbjct: 130 DLFRAIEETSNDMEYEVSMSYLEIYNEMIRDLLNPS-LGYLELR--EDSKGVIQVAGITE 186

Query: 614 FQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLR---TTGKL 670
               +  +I ++   G+  RT E T  N+ SSRSHA+L VTVR       +      G+L
Sbjct: 187 VSTINAKEIMQLLMKGNRQRTQEPTAANQTSSRSHAVLQVTVRQRSRVKNILQEVRQGRL 246

Query: 671 NLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL--RSRQGHVPFRNSKLTYL 728
            ++DLAGSER  ++   G R++E  HIN+SL ALG+ I AL  +    ++ +R+SKLT L
Sbjct: 247 FMIDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCINALSDKGSNKYINYRDSKLTRL 306

Query: 729 LQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVE 769
           L+DSL G+S+T+M+  +SP      E+  +L +A R ++++
Sbjct: 307 LKDSLGGNSRTVMIAHISPASSAFEESRNTLTYAGRAKNIK 347


>gi|30794488 kinesin family member 27 [Homo sapiens]
          Length = 1401

 Score =  201 bits (510), Expect = 3e-51
 Identities = 127/347 (36%), Positives = 187/347 (53%), Gaps = 27/347 (7%)

Query: 446 IRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQDV 505
           ++V  R+RP+  ++                  II     G+   F  D VF   ++Q +V
Sbjct: 6   VKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVII-----GRDRVFTFDFVFGKNSTQDEV 60

Query: 506 FQE-VQALVTSCIDGFNVCIFAYGQTGAGKTYTMEG------TAENPGINQRALQLLFSE 558
           +   ++ LV S I+G+N  +FAYGQTG+GKTYT+ G           GI  RA+Q +F  
Sbjct: 61  YNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPRAIQEIFQS 120

Query: 559 VQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQS 618
           + E  S  ++ + VS  E+Y E LRDLL  E   K ++ +  D  G   + G  E  V+S
Sbjct: 121 ISEHPSI-DFNVKVSYIEVYKEDLRDLLELETSMK-DLHIREDEKGNTVIVGAKECHVES 178

Query: 619 VDDINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTG---------- 668
             ++  + E G+  R T  T +NEHSSRSHA+  +++  V  +      G          
Sbjct: 179 AGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVS 238

Query: 669 KLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL---RSRQGHVPFRNSKL 725
           K + VDLAGSERV K+G  G R +E+  IN  L ALG+VI+AL   R +  H+P+R++K+
Sbjct: 239 KFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKI 298

Query: 726 TYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVELGP 772
           T LL+DSL G +KT+M+  VSP   N  E+L SLK+A R R++   P
Sbjct: 299 TRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKP 345



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 73/330 (22%), Positives = 130/330 (39%), Gaps = 53/330 (16%)

Query: 111  EKLISQAQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCEAELQELRTKPAGPCPG 170
            EK+++Q QE+  L ++L      K R+ ++ + E L QE  +   E ++LR+  A     
Sbjct: 933  EKVLNQRQELEELEADL------KKREAIVSKKEALLQE--KSHLENKKLRSSQALNTDS 984

Query: 171  CEHSQESAQLRDKLS----QLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEK 226
             + S     L  +LS    QLQ   AE K  +SE  +EV QK                  
Sbjct: 985  LKISTRLNLLEQELSEKNVQLQTSTAEEKTKISE-QVEVLQK------------------ 1025

Query: 227  AQEEERLSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQV 286
              E+++L +R  +  E + + R  SP  ++V+  +E      + A+       Q+ Q+ +
Sbjct: 1026 --EKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAIEYRNESIQNRQKSL 1083

Query: 287  AMQRQVLKEMEQQLQSSHQLTARLRAQIAMYESELERAHGQMLEEMQSL--EEDKNRAIE 344
                  L   E  +       + +  +  ++    +  + +  E  Q L  EE K + +E
Sbjct: 1084 RASFHNLSRGEANVLEKLACLSPVEIRTILFRYFNKVVNLREAERKQQLYNEEMKMKVLE 1143

Query: 345  EAFARAQVEMKAVHENLAGVRTNLLTLQPALRTLTNDYNGLKRQVRGFPLLLQEALRSVK 404
                  ++E    H  L   R   LTLQ             K   +   LLL       K
Sbjct: 1144 RDNMVRELESALDHLKLQCDRR--LTLQQ------------KEHEQKMQLLLHH----FK 1185

Query: 405  AEIGQAIEEVNSNNQELLRKYRRELQLRKK 434
             + G+ I E     ++ +++  ++L   KK
Sbjct: 1186 EQDGEGIMETFKTYEDKIQQLEKDLYFYKK 1215



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 72/370 (19%), Positives = 154/370 (41%), Gaps = 62/370 (16%)

Query: 102  LTLQVEHLKEKLISQ-------AQEVSRLRSELGGTDLEKHRDLLMVENERLRQEMRRCE 154
            LT+ ++ +KE LI +       A+ VS+  S L  T LE        + E+ + E+   +
Sbjct: 729  LTINIK-MKEDLIKELIKTGNDAKSVSKQYS-LKVTKLEH-------DAEQAKVELIETQ 779

Query: 155  AELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQLEMAESKGM----LSELNL------- 203
             +LQEL  K           Q+  + +   ++L++++ + K      L+ L++       
Sbjct: 780  KQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRAN 839

Query: 204  EVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLR---AQSPPVKYVIKT 260
            E++Q  D +   +++L+  L E+ ++ ++L   ++   + I  ++    Q   +K   + 
Sbjct: 840  ELEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAED 899

Query: 261  VEVESSKTKQALSESQARNQHLQEQ----------VAMQRQVLKEMEQQLQSSHQLTARL 310
            ++  + K ++    S    Q L EQ          V  QRQ L+E+E  L+    + ++ 
Sbjct: 900  LDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKK 959

Query: 311  RAQIAMYESELERAHGQMLEEMQSLEED------KNRAIEEAFARAQVEMK-AVHENLAG 363
             A +     E      + L   Q+L  D      +   +E+  +   V+++ +  E    
Sbjct: 960  EALL----QEKSHLENKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTK 1015

Query: 364  VRTNLLTLQPALRTLTNDYNGLKRQVRGFPLL----------LQEALRSVKAEIGQAIEE 413
            +   +  LQ     L    + +  +++   +L          L+E + +++A I    E 
Sbjct: 1016 ISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAIEYRNES 1075

Query: 414  VNSNNQELLR 423
            +  N Q+ LR
Sbjct: 1076 I-QNRQKSLR 1084


>gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]
          Length = 1153

 Score =  200 bits (509), Expect = 4e-51
 Identities = 132/348 (37%), Positives = 204/348 (58%), Gaps = 26/348 (7%)

Query: 445 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLH-KGKPVSFELDKVF----SPQ 499
           +++V  RVRP    +    E+   +    +  SII+  + K  P SF  D  +    SP+
Sbjct: 5   SVKVAVRVRPFNSRE-TSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHTSPE 63

Query: 500 ----ASQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP--GINQRAL 552
               ASQ  V+ ++ + ++    +G+NVCIFAYGQTGAGK+YTM G  E    GI  +  
Sbjct: 64  DPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQAGIIPQLC 123

Query: 553 QLLFSEVQEKASD-WEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGL 611
           + LF ++ +  ++   Y++ VS  EIY E +RDLL  + +  L +R  P      YV  L
Sbjct: 124 EELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGP--YVEDL 181

Query: 612 TEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHAL--LIVTVRGVDCSTGLRT--T 667
           ++  V S  DI  + + G+  RT   TN+NE SSRSHA+  ++ T +  D  T L T   
Sbjct: 182 SKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNETNLSTEKV 241

Query: 668 GKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL------RSRQGHVPFR 721
            K++LVDLAGSER   +GA+G+RL+E  +INKSL+ LG VI+AL      + +   +P+R
Sbjct: 242 SKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIPYR 301

Query: 722 NSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVE 769
           +S LT+LL+++L G+S+T MV  +SP + N  ETL +L++A+R + ++
Sbjct: 302 DSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIK 349


>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
          Length = 1770

 Score =  200 bits (509), Expect = 4e-51
 Identities = 132/348 (37%), Positives = 204/348 (58%), Gaps = 26/348 (7%)

Query: 445 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLH-KGKPVSFELDKVF----SPQ 499
           +++V  RVRP    +    E+   +    +  SII+  + K  P SF  D  +    SP+
Sbjct: 5   SVKVAVRVRPFNSRE-TSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHTSPE 63

Query: 500 ----ASQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP--GINQRAL 552
               ASQ  V+ ++ + ++    +G+NVCIFAYGQTGAGK+YTM G  E    GI  +  
Sbjct: 64  DPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQAGIIPQLC 123

Query: 553 QLLFSEVQEKASD-WEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGL 611
           + LF ++ +  ++   Y++ VS  EIY E +RDLL  + +  L +R  P      YV  L
Sbjct: 124 EELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGP--YVEDL 181

Query: 612 TEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHAL--LIVTVRGVDCSTGLRT--T 667
           ++  V S  DI  + + G+  RT   TN+NE SSRSHA+  ++ T +  D  T L T   
Sbjct: 182 SKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNETNLSTEKV 241

Query: 668 GKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL------RSRQGHVPFR 721
            K++LVDLAGSER   +GA+G+RL+E  +INKSL+ LG VI+AL      + +   +P+R
Sbjct: 242 SKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIPYR 301

Query: 722 NSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSVE 769
           +S LT+LL+++L G+S+T MV  +SP + N  ETL +L++A+R + ++
Sbjct: 302 DSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIK 349


>gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]
          Length = 1690

 Score =  199 bits (506), Expect = 9e-51
 Identities = 131/353 (37%), Positives = 204/353 (57%), Gaps = 32/353 (9%)

Query: 445 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLH-KGKPVSFELDKVF----SPQ 499
           +++V  RVRP    +    ++   +       +I++    K  P SF  D  +    SP+
Sbjct: 5   SVKVAVRVRPFNSRE-MSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHTSPE 63

Query: 500 ----ASQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP--GINQRAL 552
               ASQ+ V++++ + ++    +G+NVCIFAYGQTGAGK+YTM G  E    GI  +  
Sbjct: 64  DINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQGIIPQLC 123

Query: 553 QLLFSEVQEKASD-WEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGL 611
           + LFS + +  +D   Y++ VS  EIY E +RDLL  + +  L +R  P      YV  L
Sbjct: 124 EDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGP--YVEDL 181

Query: 612 TEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHAL--LIVTVRGVDCSTGLRT--T 667
           ++  V S +DI  + + G+  RT   TN+NE SSRSHA+  +I T +  D  T + T   
Sbjct: 182 SKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETNITTEKV 241

Query: 668 GKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL------------RSRQ 715
            K++LVDLAGSER   +GA+G+RL+E  +INKSL+ LG VI+AL            + + 
Sbjct: 242 SKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKNKKKKKT 301

Query: 716 GHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSV 768
             +P+R+S LT+LL+++L G+S+T MV  +SP + N  ETL +L++A+R + +
Sbjct: 302 DFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQI 354


>gi|157738629 kinesin family member 13A isoform d [Homo sapiens]
          Length = 1749

 Score =  196 bits (498), Expect = 7e-50
 Identities = 134/361 (37%), Positives = 203/361 (56%), Gaps = 43/361 (11%)

Query: 426 RRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKG 485
           RREL+L  KC   +V ++GN  V+      TK+    P    A  +              
Sbjct: 17  RRELELNTKC---VVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDY-------------- 59

Query: 486 KPVSFELDKVFSPQ-ASQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAE 543
               + +D+  + + A Q+ VF+ + + ++     G+N CIFAYGQTG+GK+++M G AE
Sbjct: 60  --CFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAE 117

Query: 544 NPGINQRALQLLFSEVQ-EKASDWEYTITVSAAEIYNEVLRDLLG-KEPQEKLEIR---- 597
             G+  R    LF  +  E+     + + VS  EIYNE +RDLL  K  ++ L++R    
Sbjct: 118 QLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKV 177

Query: 598 LCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHAL--LIVTV 655
           L P      YV GL++  V S +DI  +   G+ +RT   TN+NE SSRSHA+  +I+T 
Sbjct: 178 LGP------YVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQ 231

Query: 656 RGVDCSTGL--RTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL-- 711
              D  +G       K++LVDLAGSERV K+GA G RL+E  +INKSL+ LG VI++L  
Sbjct: 232 TLYDLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD 291

Query: 712 ----RSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRS 767
               + +   VP+R+S LT+LL+D+L G+S+T M+  +SP   N  ETL +L++A+R + 
Sbjct: 292 QAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKR 351

Query: 768 V 768
           +
Sbjct: 352 I 352



 Score = 31.2 bits (69), Expect = 4.1
 Identities = 35/147 (23%), Positives = 59/147 (40%), Gaps = 13/147 (8%)

Query: 242 ETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQ 301
           E I      + PV+ V++ +E      KQ L E ++    L+EQ  M  + L+++ QQL 
Sbjct: 586 EVIMKTLNSNDPVQNVVQVLE------KQYLEEKRSA---LEEQRLMYERELEQLRQQLS 636

Query: 302 SSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQV---EMKAVH 358
              Q  +    ++A      ++   Q  EE   L       + E   +A     E   + 
Sbjct: 637 PDRQPQSSGPDRLAYSSQTAQQKVTQWAEERDELFRQSLAKLREQLVKANTLVREANFLA 696

Query: 359 ENLAGVRTNLLTLQ-PALRTLTNDYNG 384
           E ++ +    +TLQ PA     N   G
Sbjct: 697 EEMSKLTDYQVTLQIPAANLSANRKRG 723


>gi|157738627 kinesin family member 13A isoform c [Homo sapiens]
          Length = 1757

 Score =  196 bits (498), Expect = 7e-50
 Identities = 134/361 (37%), Positives = 203/361 (56%), Gaps = 43/361 (11%)

Query: 426 RRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKG 485
           RREL+L  KC   +V ++GN  V+      TK+    P    A  +              
Sbjct: 17  RRELELNTKC---VVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDY-------------- 59

Query: 486 KPVSFELDKVFSPQ-ASQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAE 543
               + +D+  + + A Q+ VF+ + + ++     G+N CIFAYGQTG+GK+++M G AE
Sbjct: 60  --CFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAE 117

Query: 544 NPGINQRALQLLFSEVQ-EKASDWEYTITVSAAEIYNEVLRDLLG-KEPQEKLEIR---- 597
             G+  R    LF  +  E+     + + VS  EIYNE +RDLL  K  ++ L++R    
Sbjct: 118 QLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKV 177

Query: 598 LCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHAL--LIVTV 655
           L P      YV GL++  V S +DI  +   G+ +RT   TN+NE SSRSHA+  +I+T 
Sbjct: 178 LGP------YVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQ 231

Query: 656 RGVDCSTGL--RTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL-- 711
              D  +G       K++LVDLAGSERV K+GA G RL+E  +INKSL+ LG VI++L  
Sbjct: 232 TLYDLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD 291

Query: 712 ----RSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRS 767
               + +   VP+R+S LT+LL+D+L G+S+T M+  +SP   N  ETL +L++A+R + 
Sbjct: 292 QAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKR 351

Query: 768 V 768
           +
Sbjct: 352 I 352



 Score = 31.2 bits (69), Expect = 4.1
 Identities = 35/147 (23%), Positives = 59/147 (40%), Gaps = 13/147 (8%)

Query: 242 ETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQ 301
           E I      + PV+ V++ +E      KQ L E ++    L+EQ  M  + L+++ QQL 
Sbjct: 586 EVIMKTLNSNDPVQNVVQVLE------KQYLEEKRSA---LEEQRLMYERELEQLRQQLS 636

Query: 302 SSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQV---EMKAVH 358
              Q  +    ++A      ++   Q  EE   L       + E   +A     E   + 
Sbjct: 637 PDRQPQSSGPDRLAYSSQTAQQKVTQWAEERDELFRQSLAKLREQLVKANTLVREANFLA 696

Query: 359 ENLAGVRTNLLTLQ-PALRTLTNDYNG 384
           E ++ +    +TLQ PA     N   G
Sbjct: 697 EEMSKLTDYQVTLQIPAANLSANRKRG 723


>gi|157738625 kinesin family member 13A isoform b [Homo sapiens]
          Length = 1770

 Score =  196 bits (498), Expect = 7e-50
 Identities = 134/361 (37%), Positives = 203/361 (56%), Gaps = 43/361 (11%)

Query: 426 RRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKG 485
           RREL+L  KC   +V ++GN  V+      TK+    P    A  +              
Sbjct: 17  RRELELNTKC---VVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDY-------------- 59

Query: 486 KPVSFELDKVFSPQ-ASQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAE 543
               + +D+  + + A Q+ VF+ + + ++     G+N CIFAYGQTG+GK+++M G AE
Sbjct: 60  --CFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAE 117

Query: 544 NPGINQRALQLLFSEVQ-EKASDWEYTITVSAAEIYNEVLRDLLG-KEPQEKLEIR---- 597
             G+  R    LF  +  E+     + + VS  EIYNE +RDLL  K  ++ L++R    
Sbjct: 118 QLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKV 177

Query: 598 LCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHAL--LIVTV 655
           L P      YV GL++  V S +DI  +   G+ +RT   TN+NE SSRSHA+  +I+T 
Sbjct: 178 LGP------YVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQ 231

Query: 656 RGVDCSTGL--RTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL-- 711
              D  +G       K++LVDLAGSERV K+GA G RL+E  +INKSL+ LG VI++L  
Sbjct: 232 TLYDLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD 291

Query: 712 ----RSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRS 767
               + +   VP+R+S LT+LL+D+L G+S+T M+  +SP   N  ETL +L++A+R + 
Sbjct: 292 QAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKR 351

Query: 768 V 768
           +
Sbjct: 352 I 352



 Score = 31.2 bits (69), Expect = 4.1
 Identities = 35/147 (23%), Positives = 59/147 (40%), Gaps = 13/147 (8%)

Query: 242 ETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQ 301
           E I      + PV+ V++ +E      KQ L E ++    L+EQ  M  + L+++ QQL 
Sbjct: 586 EVIMKTLNSNDPVQNVVQVLE------KQYLEEKRSA---LEEQRLMYERELEQLRQQLS 636

Query: 302 SSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQV---EMKAVH 358
              Q  +    ++A      ++   Q  EE   L       + E   +A     E   + 
Sbjct: 637 PDRQPQSSGPDRLAYSSQTAQQKVTQWAEERDELFRQSLAKLREQLVKANTLVREANFLA 696

Query: 359 ENLAGVRTNLLTLQ-PALRTLTNDYNG 384
           E ++ +    +TLQ PA     N   G
Sbjct: 697 EEMSKLTDYQVTLQIPAANLSANRKRG 723


>gi|157738621 kinesin family member 13A isoform a [Homo sapiens]
          Length = 1805

 Score =  196 bits (498), Expect = 7e-50
 Identities = 134/361 (37%), Positives = 203/361 (56%), Gaps = 43/361 (11%)

Query: 426 RRELQLRKKCHNELVRLKGNIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKG 485
           RREL+L  KC   +V ++GN  V+      TK+    P    A  +              
Sbjct: 17  RRELELNTKC---VVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDY-------------- 59

Query: 486 KPVSFELDKVFSPQ-ASQQDVFQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAE 543
               + +D+  + + A Q+ VF+ + + ++     G+N CIFAYGQTG+GK+++M G AE
Sbjct: 60  --CFWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAE 117

Query: 544 NPGINQRALQLLFSEVQ-EKASDWEYTITVSAAEIYNEVLRDLLG-KEPQEKLEIR---- 597
             G+  R    LF  +  E+     + + VS  EIYNE +RDLL  K  ++ L++R    
Sbjct: 118 QLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKV 177

Query: 598 LCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHAL--LIVTV 655
           L P      YV GL++  V S +DI  +   G+ +RT   TN+NE SSRSHA+  +I+T 
Sbjct: 178 LGP------YVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQ 231

Query: 656 RGVDCSTGL--RTTGKLNLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL-- 711
              D  +G       K++LVDLAGSERV K+GA G RL+E  +INKSL+ LG VI++L  
Sbjct: 232 TLYDLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLAD 291

Query: 712 ----RSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRS 767
               + +   VP+R+S LT+LL+D+L G+S+T M+  +SP   N  ETL +L++A+R + 
Sbjct: 292 QAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKR 351

Query: 768 V 768
           +
Sbjct: 352 I 352



 Score = 31.2 bits (69), Expect = 4.1
 Identities = 35/147 (23%), Positives = 59/147 (40%), Gaps = 13/147 (8%)

Query: 242 ETIASLRAQSPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQ 301
           E I      + PV+ V++ +E      KQ L E ++    L+EQ  M  + L+++ QQL 
Sbjct: 586 EVIMKTLNSNDPVQNVVQVLE------KQYLEEKRSA---LEEQRLMYERELEQLRQQLS 636

Query: 302 SSHQLTARLRAQIAMYESELERAHGQMLEEMQSLEEDKNRAIEEAFARAQV---EMKAVH 358
              Q  +    ++A      ++   Q  EE   L       + E   +A     E   + 
Sbjct: 637 PDRQPQSSGPDRLAYSSQTAQQKVTQWAEERDELFRQSLAKLREQLVKANTLVREANFLA 696

Query: 359 ENLAGVRTNLLTLQ-PALRTLTNDYNG 384
           E ++ +    +TLQ PA     N   G
Sbjct: 697 EEMSKLTDYQVTLQIPAANLSANRKRG 723


>gi|7661878 kinesin family member 14 [Homo sapiens]
          Length = 1648

 Score =  194 bits (492), Expect = 4e-49
 Identities = 183/642 (28%), Positives = 298/642 (46%), Gaps = 56/642 (8%)

Query: 164 PAGPCPGCEHSQESAQLRDKLSQL---QLEMAESKGMLSELNLEVQQKTD-----RLAEV 215
           P  P P    + +    R+K S L   +LE    K   + L L+ + KTD     + AE+
Sbjct: 79  PLTPNPVGRLALQRRTTRNKESSLLVSELEDTTEKTAETRLTLQRRAKTDSAEKWKTAEI 138

Query: 216 ELRLKDCLAEKAQEEERLSRRLRDSHETIASLR----AQSPPVKYVIKTVEVESSKT-KQ 270
           +            E   +S+  R +   + + +    A S P+    + +E+ + K  K+
Sbjct: 139 DSVKMTLNVGGETENNGVSKESRTNVRIVNNAKNSFVASSVPLDEDPQVIEMMADKKYKE 198

Query: 271 ALSESQARNQHLQEQVAMQRQVLKEMEQQ--LQSSHQLTARLRAQIAMYESELERAHGQM 328
             S     N+++  + +  R  +  + Q   ++S H  T   ++++ +        + + 
Sbjct: 199 TFSAPSRANENVALKYSSNRPPIASLSQTEVVRSGHLTTKPTQSKLDIKVLGTGNLYHRS 258

Query: 329 LEEMQSLEEDKNRAIEEAFARAQVEMKAVHENLAGVRTNLLTLQ-PALRTLTNDYNGLKR 387
           + +  +   +K  ++E+     +   K   E+    + +L  L+ PA   L N  + L+ 
Sbjct: 259 IGKEIAKTSNKFGSLEK-----RTPTKCTTEHKLTTKCSLPQLKSPAPSILKNRMSNLQV 313

Query: 388 QVRGFPLLLQEALRSVKAEIGQAIEEVNSNNQELLRKYRRELQLRKKCHNELVRLKGNIR 447
           + R     L             A ++  S    +L +    +Q      + L      + 
Sbjct: 314 KQRPKSSFL-------------ANKQERSAENTILPEEETVVQNTSAGKDPLKVENSQVT 360

Query: 448 VIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGK-----PVSF-ELDKVFSPQAS 501
           V  RVRP TK + +  +A+  V     + ++ H   K        VSF   D+     AS
Sbjct: 361 VAVRVRPFTKRE-KIEKASQVVFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYAS 419

Query: 502 QQDVFQEVQA-LVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENPGINQRALQLLFSEVQ 560
           Q  V++++ A L+    +GFN C+FAYGQTG+GK+YTM G +E PGI  R  + LFS+V 
Sbjct: 420 QTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEPGIIPRFCEDLFSQVA 479

Query: 561 EK-ASDWEYTITVSAAEIYNEVLRDLL---GKEPQEKLEIRLCPDGSGQLYVPGLTEFQV 616
            K   +  Y I +S  E+YNE + DLL    +  Q K  +R+        YV  L+   V
Sbjct: 480 RKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYGPYVEALSMNIV 539

Query: 617 QSVDDINKVFEFGHTNRTTEFTNLNEHSSRSHAL--LIVTVRGVDCSTG----LRTTGKL 670
            S  DI    E G+  R T  T +N+ SSRSH++  L++T    +   G     R T ++
Sbjct: 540 SSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEGEEHDHRITSRI 599

Query: 671 NLVDLAGSERVGKSGAEGSRLREAQHINKSLSALGDVIAAL----RSRQGHVPFRNSKLT 726
           NL+DLAGSER   +   G RL+E   INKSL  LG VI+AL      R   +P+R S LT
Sbjct: 600 NLIDLAGSERCSTAHTNGDRLKEGVSINKSLLTLGKVISALSEQANQRSVFIPYRESVLT 659

Query: 727 YLLQDSLSGDSKTLMVVQVSPVEKNTSETLYSLKFAERVRSV 768
           +LL++SL G+SKT M+  +SP   N  ETL +L++A + R +
Sbjct: 660 WLLKESLGGNSKTAMIATISPAASNIEETLSTLRYANQARLI 701



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 37/173 (21%), Positives = 76/173 (43%), Gaps = 22/173 (12%)

Query: 133  EKHRDLLMVENERLRQEMRRCEAELQELRTKPAGPCPGCEHSQESAQLRDKLSQLQL--E 190
            E  +D    +NE L  +  + EAE++E + K        E   +  Q+  +++Q +L  +
Sbjct: 919  EGPKDFEFAKNELLMAQRSQLEAEIKEAQLKAK------EEMMQGIQIAKEMAQQELSSQ 972

Query: 191  MAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEERLSRRLRDSHETIASLRAQ 250
             A  +  +  L  E+++++ R    E+  +     K +E E+  + L             
Sbjct: 973  KAAYESKIKALEAELREESQRKKMQEINNQKA-NHKIEELEKAKQHLEQE---------- 1021

Query: 251  SPPVKYVIKTVEVESSKTKQALSESQARNQHLQEQVAMQRQVLKEMEQQLQSS 303
               +    K +E+E+  TKQAL +   R+  + E +  ++Q + +  Q LQ +
Sbjct: 1022 ---IYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQILQQN 1071


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.129    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,986,685
Number of Sequences: 37866
Number of extensions: 1578486
Number of successful extensions: 14365
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 299
Number of HSP's successfully gapped in prelim test: 891
Number of HSP's that attempted gapping in prelim test: 9475
Number of HSP's gapped (non-prelim): 3486
length of query: 833
length of database: 18,247,518
effective HSP length: 111
effective length of query: 722
effective length of database: 14,044,392
effective search space: 10140051024
effective search space used: 10140051024
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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