Guide to the Human Genome
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Search of human proteins with 94400925

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|94400925 synaptonemal complex protein 2-like [Homo sapiens]
         (812 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|94400925 synaptonemal complex protein 2-like [Homo sapiens]       1605   0.0  
gi|38373673 synaptonemal complex protein 2 [Homo sapiens]             278   1e-74
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    45   4e-04
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]                         44   5e-04
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi...    44   5e-04
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    44   6e-04
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    44   6e-04
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    44   6e-04
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...    44   6e-04
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...    44   6e-04
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             44   8e-04
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]         43   0.001
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]         43   0.001
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]         43   0.001
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]         43   0.001
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]         43   0.001
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]         43   0.001
gi|48255931 hepatoma-derived growth factor-related protein 2 iso...    43   0.001
gi|14249158 hepatoma-derived growth factor-related protein 2 iso...    43   0.001
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     42   0.002
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof...    42   0.002
gi|190194423 SPARC-like 1 [Homo sapiens]                               42   0.002
gi|190341024 SPARC-like 1 [Homo sapiens]                               42   0.002
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     42   0.003
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     42   0.003
gi|31657123 Hermansky-Pudlak syndrome 5 isoform a [Homo sapiens]       41   0.004
gi|31657125 Hermansky-Pudlak syndrome 5 isoform b [Homo sapiens]       41   0.004
gi|31657127 Hermansky-Pudlak syndrome 5 isoform b [Homo sapiens]       41   0.004
gi|11225260 DNA topoisomerase I [Homo sapiens]                         41   0.005
gi|109637791 transcription factor-like nuclear regulator [Homo s...    41   0.005

>gi|94400925 synaptonemal complex protein 2-like [Homo sapiens]
          Length = 812

 Score = 1605 bits (4155), Expect = 0.0
 Identities = 812/812 (100%), Positives = 812/812 (100%)

Query: 1   MQAKNKDALQPIKEDRTGKAQDDAFWLQSLITDAFHDKGFQKIKEYFQQKESHFPQKYNR 60
           MQAKNKDALQPIKEDRTGKAQDDAFWLQSLITDAFHDKGFQKIKEYFQQKESHFPQKYNR
Sbjct: 1   MQAKNKDALQPIKEDRTGKAQDDAFWLQSLITDAFHDKGFQKIKEYFQQKESHFPQKYNR 60

Query: 61  LLLYRLDRSINKELDKNEFQSVSLLLKCIQRFLVDGLKEDEPLLIRQGLIPKLVSWFERT 120
           LLLYRLDRSINKELDKNEFQSVSLLLKCIQRFLVDGLKEDEPLLIRQGLIPKLVSWFERT
Sbjct: 61  LLLYRLDRSINKELDKNEFQSVSLLLKCIQRFLVDGLKEDEPLLIRQGLIPKLVSWFERT 120

Query: 121 TGILTSEGLASDTSLICVIEDFFDTALIISRSSSEGKIQMLDSFLLSLGFLVTEKTVNHL 180
           TGILTSEGLASDTSLICVIEDFFDTALIISRSSSEGKIQMLDSFLLSLGFLVTEKTVNHL
Sbjct: 121 TGILTSEGLASDTSLICVIEDFFDTALIISRSSSEGKIQMLDSFLLSLGFLVTEKTVNHL 180

Query: 181 LQQEGLKTFNCILHAVPREERKKFPLSEGMCHLMKDLARTLLTVGDYDQQVAISEALCRL 240
           LQQEGLKTFNCILHAVPREERKKFPLSEGMCHLMKDLARTLLTVGDYDQQVAISEALCRL
Sbjct: 181 LQQEGLKTFNCILHAVPREERKKFPLSEGMCHLMKDLARTLLTVGDYDQQVAISEALCRL 240

Query: 241 TIKKSRDELVHKWFDDEVIAEAFKEIKDREFETDSRRFLNHLNNRLGDQRRVYSFPCIAA 300
           TIKKSRDELVHKWFDDEVIAEAFKEIKDREFETDSRRFLNHLNNRLGDQRRVYSFPCIAA
Sbjct: 241 TIKKSRDELVHKWFDDEVIAEAFKEIKDREFETDSRRFLNHLNNRLGDQRRVYSFPCIAA 300

Query: 301 FADEHEMRKPADEKLEKFWIDFNLGSQSVTFYIDNAENTLWDSVTLPKEAVMNFSITETE 360
           FADEHEMRKPADEKLEKFWIDFNLGSQSVTFYIDNAENTLWDSVTLPKEAVMNFSITETE
Sbjct: 301 FADEHEMRKPADEKLEKFWIDFNLGSQSVTFYIDNAENTLWDSVTLPKEAVMNFSITETE 360

Query: 361 KIKIFIIYLKKPMIISYKEVMKIEIHFDLQFNISQVSIQALGEDKQMLPDQTKISSELFS 420
           KIKIFIIYLKKPMIISYKEVMKIEIHFDLQFNISQVSIQALGEDKQMLPDQTKISSELFS
Sbjct: 361 KIKIFIIYLKKPMIISYKEVMKIEIHFDLQFNISQVSIQALGEDKQMLPDQTKISSELFS 420

Query: 421 KSDKEDRESPSGLERETEQAEESTNMVEFMSAEDDRCLITLHLNDQSEPPVIGEPASDSH 480
           KSDKEDRESPSGLERETEQAEESTNMVEFMSAEDDRCLITLHLNDQSEPPVIGEPASDSH
Sbjct: 421 KSDKEDRESPSGLERETEQAEESTNMVEFMSAEDDRCLITLHLNDQSEPPVIGEPASDSH 480

Query: 481 LQPVPPFGVPDFPQQPKSHYRKHLFSESNQDSSTSELSWTSNQKKKSLKSYSSRKKTRTR 540
           LQPVPPFGVPDFPQQPKSHYRKHLFSESNQDSSTSELSWTSNQKKKSLKSYSSRKKTRTR
Sbjct: 481 LQPVPPFGVPDFPQQPKSHYRKHLFSESNQDSSTSELSWTSNQKKKSLKSYSSRKKTRTR 540

Query: 541 SNLRILPVFPPSSGSGHEKDQAKLLSPSEKEIPEQNNTTSPKTSEQKFQDSFAFLTAEDS 600
           SNLRILPVFPPSSGSGHEKDQAKLLSPSEKEIPEQNNTTSPKTSEQKFQDSFAFLTAEDS
Sbjct: 541 SNLRILPVFPPSSGSGHEKDQAKLLSPSEKEIPEQNNTTSPKTSEQKFQDSFAFLTAEDS 600

Query: 601 AQKTELQDPHSLSELSSLKHSEDEEKPKIVNQESLTESTSLKHKLRNLEDKDIPEGSFAK 660
           AQKTELQDPHSLSELSSLKHSEDEEKPKIVNQESLTESTSLKHKLRNLEDKDIPEGSFAK
Sbjct: 601 AQKTELQDPHSLSELSSLKHSEDEEKPKIVNQESLTESTSLKHKLRNLEDKDIPEGSFAK 660

Query: 661 SQQSRLEEEVASGSPFSITEERELPEGISTSSLEVVPENLNGSAILPTFENFTKKRKRKY 720
           SQQSRLEEEVASGSPFSITEERELPEGISTSSLEVVPENLNGSAILPTFENFTKKRKRKY
Sbjct: 661 SQQSRLEEEVASGSPFSITEERELPEGISTSSLEVVPENLNGSAILPTFENFTKKRKRKY 720

Query: 721 ELRYRKRPFNSENAKKAPDCLIKLLNQMQLFRLNKLERFQNLVLQELSSLKQDIQALEHL 780
           ELRYRKRPFNSENAKKAPDCLIKLLNQMQLFRLNKLERFQNLVLQELSSLKQDIQALEHL
Sbjct: 721 ELRYRKRPFNSENAKKAPDCLIKLLNQMQLFRLNKLERFQNLVLQELSSLKQDIQALEHL 780

Query: 781 EKEVLEFWGKQSADLQSFCDLQVLRFNSTQTS 812
           EKEVLEFWGKQSADLQSFCDLQVLRFNSTQTS
Sbjct: 781 EKEVLEFWGKQSADLQSFCDLQVLRFNSTQTS 812


>gi|38373673 synaptonemal complex protein 2 [Homo sapiens]
          Length = 1530

 Score =  278 bits (712), Expect = 1e-74
 Identities = 158/386 (40%), Positives = 240/386 (62%), Gaps = 10/386 (2%)

Query: 27  LQSLITDAFHDKGFQKIKEYFQQKESHFPQ-KYNRLLLYRLDRSINKELDKNEFQSVSLL 85
           L+  I DA     F+ +K   Q       + K ++   +++D  I +EL+K +  +VS +
Sbjct: 10  LEKCIDDALRKNDFKPLKTLLQIDICEDVKIKCSKQFFHKVDNLICRELNKEDIHNVSAI 69

Query: 86  L----KCIQRFLVDGLKEDEPLLIRQGLIPKLVSWFERTTGILTSEGLASDTSLICVIED 141
           L    +C +   V G +     +I+QGLI K+V+WFE++  I+ S+G + D +++ +IED
Sbjct: 70  LVSVGRCGKNISVLG-QAGLLTMIKQGLIQKMVAWFEKSKDIIQSQGNSKDEAVLNMIED 128

Query: 142 FFDTALIISRSSSEGKIQMLDSFLLSLGFLVTEKTVNHLLQQEGLKTFNCILHAVPREER 201
             D  L+I   S EGK Q+++SF+  +  LV +  VN  +QQE +K  N +L  +P++ R
Sbjct: 129 LVDLLLVIHDVSDEGKKQVVESFVPRICSLVIDSRVNICIQQEIIKKMNAMLDKMPQDAR 188

Query: 202 KKFPLSEGMCHLMKDLARTLLTVGDYDQQVAISEALCRLTIKKSRDELVHKWFDDEVIAE 261
           K     E M  LM  +   +L  GDYD QV I EALCR+T +K R EL H+WF  + IA+
Sbjct: 189 KILSNQE-MLILMSSMGERILDAGDYDLQVGIVEALCRMTTEKQRQELAHQWFSMDFIAK 247

Query: 262 AFKEIKDREFETDSRRFLNHLNNRLGDQRRVYSFPCIAAFADEHEMRKPADEKLEKFWID 321
           AFK IKD EFETD R FLN +N  LGD+RRV++FPC++AF D++E++ P+DEKLE+FWID
Sbjct: 248 AFKRIKDSEFETDCRIFLNLVNGMLGDKRRVFTFPCLSAFLDKYELQIPSDEKLEEFWID 307

Query: 322 FNLGSQSVTFYI--DNAENTLWDSVTLPKEAVMNFSITETEKIKIFIIYLKKPMIISYKE 379
           FNLGSQ+++FYI  DN ++  W++VT+P+E V  +SI   E  K+  I LK  + IS +E
Sbjct: 308 FNLGSQTLSFYIAGDNDDHQ-WEAVTVPEEKVQIYSIEVRESKKLLTIILKNTVKISKRE 366

Query: 380 VMKIEIHFDLQFNISQVSIQALGEDK 405
             ++ ++FD    I+ V+ +  G  K
Sbjct: 367 GKELLLYFDASLEITNVTQKIFGATK 392



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 93/408 (22%), Positives = 174/408 (42%), Gaps = 43/408 (10%)

Query: 434  ERETEQAEESTNMVEFMSAEDDRCLITLHLNDQSEPPVIGEPASDSHLQPVPPFGVPDFP 493
            E E E +++  N      A  D CL      D S   + G P+S    + +      DF 
Sbjct: 1074 ETEKELSKQWKNSSLLKDAIRDNCL------DLSPRSLSGSPSSIEVTRCIEKITEKDFT 1127

Query: 494  Q------QPKSHYRKHLFSESNQDSSTSELSWTSNQKKKSLKSYSSRKKTRTRSNLRI-L 546
            Q      +  S Y K    ES   +S S +  T    K + K++    ++ +     + L
Sbjct: 1128 QDYDCITKSISPYPKTSSLESL--NSNSGVGGTIKSPKNNEKNFLCASESCSPIPRPLFL 1185

Query: 547  PVFPPSSGSG--HEKDQAKLLSPSEKEIPEQNNTTSPKTSEQKFQDSFAFLTAEDSAQKT 604
            P   P+  +   + K  + L+   E +     +  S  +SE++F +  +    E+  Q +
Sbjct: 1186 PRHTPTKSNTIVNRKKISSLVLTQETQNSNSYSDVSSYSSEERFMEIESPHINENYIQ-S 1244

Query: 605  ELQDPHSLSELSSLKHSEDEEKPKIVNQESLTESTSLKHKLRNLEDKDIP-EGSFAKSQQ 663
            + ++ H  S LS  K SE  EK      +   ++T +    ++L  K I  E + + S +
Sbjct: 1245 KREESHLASSLS--KSSEGREKTWF---DMPCDATHVSGPTQHLSRKRIYIEDNLSNSNE 1299

Query: 664  SRLEEEV---ASGSPFSITEERELPEGISTSSLEVVPENLNGSAI--------------- 705
              +EE+    A+  P  + +  +    I   S  V   + N  +I               
Sbjct: 1300 VEMEEKGERRANLLPKKLCKIEDADHHIHKMSESVSSLSTNDFSIPWETWQNEFAGIEMT 1359

Query: 706  LPTFENFTKKRKRKYELRYRKRP-FNSENAKKAPDCLIKLLNQMQLFRLNKLERFQNLVL 764
              T+E    + KR+  +R++    F +++ K A   L  + +Q Q  R+ KL++FQ +++
Sbjct: 1360 YETYERLNSEFKRRNNIRHKMLSYFTTQSWKTAQQHLRTMNHQSQDSRIKKLDKFQFIII 1419

Query: 765  QELSSLKQDIQALEHLEKEVLEFWGKQSADLQSFCDLQVLRFNSTQTS 812
            +EL + ++D Q+L+ LEKE ++FW K      ++   +  R +  +TS
Sbjct: 1420 EELENFEKDSQSLKDLEKEFVDFWEKIFQKFSAYQKSEQQRLHLLKTS 1467


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 69/304 (22%), Positives = 118/304 (38%), Gaps = 36/304 (11%)

Query: 415 SSELFSKSDKEDRESPSGLERETEQAEE----------STNMVEFMSAEDDRCLITLHLN 464
           SS   S SD  + E  +   ++T   ++          +T   +  S+ED     +    
Sbjct: 220 SSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDS----SSDEE 275

Query: 465 DQSEPPVIGEPASDSHLQP--VPPFGVPDFPQQPKSHYRKHLFSESNQDSSTSELSWTSN 522
           ++ + P+  +P   S + P   PP       Q PK    K    ES++DSS    S +  
Sbjct: 276 EEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEE 335

Query: 523 QKKKSLKSYSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLSPSEKEIPEQNNTTSP- 581
           +KK   K+  S+  T+     +       SS S   +D     +PS+     +N++  P 
Sbjct: 336 EKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDE---APSKPAGTTKNSSNKPA 392

Query: 582 -KTSEQKFQDSFAFLTAEDSAQKTELQDPHSLSELSSLKHSEDEEKPKIVNQESLTESTS 640
             T     + + A        QK   +   S S       SE+E+  K+V   + T+  +
Sbjct: 393 VTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMV---ATTKPKA 449

Query: 641 LKHKLRNLEDKDIPEGSFAKSQQSRLEEEVASGSPFSITEERELPEGISTSSLEVVPENL 700
                 +L  K  P+GS           + +S S  S +EE E  E  S S+++  P+ +
Sbjct: 450 TAKAALSLPAKQAPQGS----------RDSSSDSDSSSSEEEE--EKTSKSAVKKKPQKV 497

Query: 701 NGSA 704
            G A
Sbjct: 498 AGGA 501



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 41/184 (22%), Positives = 73/184 (39%), Gaps = 23/184 (12%)

Query: 508 SNQDSSTSELSWTSNQKKKSLKSYSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLSP 567
           S   SS S+ S +  +++K+ KS   +K  +               G     + +     
Sbjct: 466 SRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDS 525

Query: 568 SEKEIPEQNNTTSPKTSEQKFQDSFAFLTAEDSAQKTELQDPHSLSELSSLKHSEDEEKP 627
           SE+E  +     SP+    K   + A LTA++                 + K+SE+EE+ 
Sbjct: 526 SEEEEEKLKGKGSPRPQAPKANGTSA-LTAQNG---------------KAAKNSEEEEEE 569

Query: 628 KIVNQESLTESTSLKHKLRN--LEDKDIPEGSFAKSQ-----QSRLEEEVASGSPFSITE 680
           K      +++S SLK + +N   ++ + P+    K Q       R + E  + SPF    
Sbjct: 570 KKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKRKKGEKRASSPFRRVR 629

Query: 681 EREL 684
           E E+
Sbjct: 630 EEEI 633


>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
          Length = 4377

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 58/259 (22%), Positives = 107/259 (41%), Gaps = 21/259 (8%)

Query: 429  SPSGLERETEQAEESTNMVEFMSA-----EDDRCLITLHLNDQSEPPVIGEPASDSHLQP 483
            SP G E  +E+ EE+ ++ + M A     +  + L  L  +  +  P + + A+++  Q 
Sbjct: 2256 SPPGGEGASERIEETMSVHDIMKAFQSGRDPSKELAGLFEHKSAVSPDVHKSAAETSAQH 2315

Query: 484  VPPFGVPDFPQQPKSHYRKHLFSESNQDSSTSELSWTSNQKKKSLKSYSSRKK-TRTRSN 542
                   D   +PK      +  E    +  +E+     +K    + Y  +K  +R   N
Sbjct: 2316 AEK----DNQMKPKLERIIEVHIEKGNQAEPTEVIIRETKKHPEKEMYVYQKDLSRGDIN 2371

Query: 543  LR-ILP----VFPPSSGSGHEKDQAKLLSPSEKEIPEQNNTTSPKTSEQKFQDSFAFLTA 597
            L+  LP     FP S   G ++++      S     E +   +P + E+  + S A L +
Sbjct: 2372 LKDFLPEKHDAFPCSEEQGQQEEEELTAEESLPSYLESSRVNTPVSQEEDSRPSSAQLIS 2431

Query: 598  EDSAQKTELQDPHSL----SELSSLKHSEDEEKPKIVNQESLTESTSLKHKLRNLEDKDI 653
            +DS +  +L   HS+     ELS L+        K++  E L  S S   +  ++ D   
Sbjct: 2432 DDSYKTLKLLSQHSIEYHDDELSELRGESYRFAEKMLLSEKLDVSHSDTEE--SVTDHAG 2489

Query: 654  PEGSFAKSQQSRLEEEVAS 672
            P  S  +    R  E++A+
Sbjct: 2490 PPSSELQGSDKRSREKIAT 2508


>gi|195976782 Paf1/RNA polymerase II complex component [Homo
           sapiens]
          Length = 710

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 51/235 (21%), Positives = 91/235 (38%), Gaps = 26/235 (11%)

Query: 506 SESNQDSSTSELSWT--SNQKKKSLKSYSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAK 563
           + S+ ++S S+  WT  SN+ KK  K+    KK   +           SSGS  +   A+
Sbjct: 91  ASSDSETSDSDDEWTFGSNKNKKKGKARKIEKKGTMKKQANKTA----SSGSSDKDSSAE 146

Query: 564 LLSPSEKEIPEQNNTTSPKTS-------EQKFQDSFAFLTAEDSAQKTELQDPHSLSELS 616
             +P E E+ + ++ +S  +S       +++F D +      D   +  L       E  
Sbjct: 147 SSAPEEGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARL-------EQM 199

Query: 617 SLKHSEDEEKPKIVNQESLTESTSLKHKLRNLEDKDIPEGSFAKSQQSRLEEEVASGSPF 676
           + K  E E   +I  +E L     +K KL+  + K+       K ++ + EEE       
Sbjct: 200 TEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKE------KKEKKKKQEEEQEKKKLT 253

Query: 677 SITEERELPEGISTSSLEVVPENLNGSAILPTFENFTKKRKRKYELRYRKRPFNS 731
            I E +         S      +    A+        K++ R  EL  +K+P  +
Sbjct: 254 QIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKT 308


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 68/327 (20%), Positives = 126/327 (38%), Gaps = 68/327 (20%)

Query: 417 ELFSKSDKEDRESPSGLERETEQAEESTNMVEFMSAEDDRCLITLHLNDQSEPPVIGEPA 476
           E   +  + +R+     + + EQ E      E     + R  ++ H     E     +  
Sbjct: 158 EQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED--YSDKV 215

Query: 477 SDSHLQPVPPFGVPDFPQQPKSHY-----RKHLFSESNQDSST-SELSWTSNQKKKSLKS 530
             SH    PP       + P+  +     RK +  E  ++    S+L   S+ ++K+  +
Sbjct: 216 KASHWSRSPP-------RPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSA 268

Query: 531 YSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLSPSEKEIPEQNNTTSPKTSEQKFQD 590
            SS  +                SGSG E+++       E+E  E+  +TS ++ E++ ++
Sbjct: 269 ESSSAE----------------SGSGSEEEE------EEEEEEEEEGSTSEESEEEEEEE 306

Query: 591 SFAFLTAEDSAQKTELQDPHSLSELSSLKHSEDEEKPKIVNQESLTESTSLKHKLRNLED 650
                  E++   +E     S  E+S  + SEDEE+    N+  L               
Sbjct: 307 EEE---EEETGSNSEEASEQSAEEVSEEEMSEDEERE---NENHLLV------------- 347

Query: 651 KDIPEGSFAK--SQQSRLEEEVASGSPFS--ITEERELPEGISTSSLEVVPE------NL 700
             +PE  F +   +    EEEV  G+P S  +TE   +P+  + S +E+  E       L
Sbjct: 348 --VPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPAL 405

Query: 701 NGSAILPTFENFTKKRKRKYELRYRKR 727
            G   +  F+   +  +  Y + YR +
Sbjct: 406 QGCRSVEEFQCLNRIEEGTYGVVYRAK 432


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 68/327 (20%), Positives = 126/327 (38%), Gaps = 68/327 (20%)

Query: 417 ELFSKSDKEDRESPSGLERETEQAEESTNMVEFMSAEDDRCLITLHLNDQSEPPVIGEPA 476
           E   +  + +R+     + + EQ E      E     + R  ++ H     E     +  
Sbjct: 167 EQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED--YSDKV 224

Query: 477 SDSHLQPVPPFGVPDFPQQPKSHY-----RKHLFSESNQDSST-SELSWTSNQKKKSLKS 530
             SH    PP       + P+  +     RK +  E  ++    S+L   S+ ++K+  +
Sbjct: 225 KASHWSRSPP-------RPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSA 277

Query: 531 YSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLSPSEKEIPEQNNTTSPKTSEQKFQD 590
            SS  +                SGSG E+++       E+E  E+  +TS ++ E++ ++
Sbjct: 278 ESSSAE----------------SGSGSEEEE------EEEEEEEEEGSTSEESEEEEEEE 315

Query: 591 SFAFLTAEDSAQKTELQDPHSLSELSSLKHSEDEEKPKIVNQESLTESTSLKHKLRNLED 650
                  E++   +E     S  E+S  + SEDEE+    N+  L               
Sbjct: 316 EEE---EEETGSNSEEASEQSAEEVSEEEMSEDEERE---NENHLLV------------- 356

Query: 651 KDIPEGSFAK--SQQSRLEEEVASGSPFS--ITEERELPEGISTSSLEVVPE------NL 700
             +PE  F +   +    EEEV  G+P S  +TE   +P+  + S +E+  E       L
Sbjct: 357 --VPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPAL 414

Query: 701 NGSAILPTFENFTKKRKRKYELRYRKR 727
            G   +  F+   +  +  Y + YR +
Sbjct: 415 QGCRSVEEFQCLNRIEEGTYGVVYRAK 441


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 68/327 (20%), Positives = 126/327 (38%), Gaps = 68/327 (20%)

Query: 417 ELFSKSDKEDRESPSGLERETEQAEESTNMVEFMSAEDDRCLITLHLNDQSEPPVIGEPA 476
           E   +  + +R+     + + EQ E      E     + R  ++ H     E     +  
Sbjct: 135 EQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED--YSDKV 192

Query: 477 SDSHLQPVPPFGVPDFPQQPKSHY-----RKHLFSESNQDSST-SELSWTSNQKKKSLKS 530
             SH    PP       + P+  +     RK +  E  ++    S+L   S+ ++K+  +
Sbjct: 193 KASHWSRSPP-------RPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSA 245

Query: 531 YSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLSPSEKEIPEQNNTTSPKTSEQKFQD 590
            SS  +                SGSG E+++       E+E  E+  +TS ++ E++ ++
Sbjct: 246 ESSSAE----------------SGSGSEEEE------EEEEEEEEEGSTSEESEEEEEEE 283

Query: 591 SFAFLTAEDSAQKTELQDPHSLSELSSLKHSEDEEKPKIVNQESLTESTSLKHKLRNLED 650
                  E++   +E     S  E+S  + SEDEE+    N+  L               
Sbjct: 284 EEE---EEETGSNSEEASEQSAEEVSEEEMSEDEERE---NENHLLV------------- 324

Query: 651 KDIPEGSFAK--SQQSRLEEEVASGSPFS--ITEERELPEGISTSSLEVVPE------NL 700
             +PE  F +   +    EEEV  G+P S  +TE   +P+  + S +E+  E       L
Sbjct: 325 --VPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPAL 382

Query: 701 NGSAILPTFENFTKKRKRKYELRYRKR 727
            G   +  F+   +  +  Y + YR +
Sbjct: 383 QGCRSVEEFQCLNRIEEGTYGVVYRAK 409


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 68/327 (20%), Positives = 126/327 (38%), Gaps = 68/327 (20%)

Query: 417 ELFSKSDKEDRESPSGLERETEQAEESTNMVEFMSAEDDRCLITLHLNDQSEPPVIGEPA 476
           E   +  + +R+     + + EQ E      E     + R  ++ H     E     +  
Sbjct: 124 EQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED--YSDKV 181

Query: 477 SDSHLQPVPPFGVPDFPQQPKSHY-----RKHLFSESNQDSST-SELSWTSNQKKKSLKS 530
             SH    PP       + P+  +     RK +  E  ++    S+L   S+ ++K+  +
Sbjct: 182 KASHWSRSPP-------RPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSA 234

Query: 531 YSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLSPSEKEIPEQNNTTSPKTSEQKFQD 590
            SS  +                SGSG E+++       E+E  E+  +TS ++ E++ ++
Sbjct: 235 ESSSAE----------------SGSGSEEEE------EEEEEEEEEGSTSEESEEEEEEE 272

Query: 591 SFAFLTAEDSAQKTELQDPHSLSELSSLKHSEDEEKPKIVNQESLTESTSLKHKLRNLED 650
                  E++   +E     S  E+S  + SEDEE+    N+  L               
Sbjct: 273 EEE---EEETGSNSEEASEQSAEEVSEEEMSEDEERE---NENHLLV------------- 313

Query: 651 KDIPEGSFAK--SQQSRLEEEVASGSPFS--ITEERELPEGISTSSLEVVPE------NL 700
             +PE  F +   +    EEEV  G+P S  +TE   +P+  + S +E+  E       L
Sbjct: 314 --VPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPAL 371

Query: 701 NGSAILPTFENFTKKRKRKYELRYRKR 727
            G   +  F+   +  +  Y + YR +
Sbjct: 372 QGCRSVEEFQCLNRIEEGTYGVVYRAK 398


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           2 [Homo sapiens]
          Length = 782

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 68/327 (20%), Positives = 126/327 (38%), Gaps = 68/327 (20%)

Query: 417 ELFSKSDKEDRESPSGLERETEQAEESTNMVEFMSAEDDRCLITLHLNDQSEPPVIGEPA 476
           E   +  + +R+     + + EQ E      E     + R  ++ H     E     +  
Sbjct: 169 EQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED--YSDKV 226

Query: 477 SDSHLQPVPPFGVPDFPQQPKSHY-----RKHLFSESNQDSST-SELSWTSNQKKKSLKS 530
             SH    PP       + P+  +     RK +  E  ++    S+L   S+ ++K+  +
Sbjct: 227 KASHWSRSPP-------RPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSA 279

Query: 531 YSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLSPSEKEIPEQNNTTSPKTSEQKFQD 590
            SS  +                SGSG E+++       E+E  E+  +TS ++ E++ ++
Sbjct: 280 ESSSAE----------------SGSGSEEEE------EEEEEEEEEGSTSEESEEEEEEE 317

Query: 591 SFAFLTAEDSAQKTELQDPHSLSELSSLKHSEDEEKPKIVNQESLTESTSLKHKLRNLED 650
                  E++   +E     S  E+S  + SEDEE+    N+  L               
Sbjct: 318 EEE---EEETGSNSEEASEQSAEEVSEEEMSEDEERE---NENHLLV------------- 358

Query: 651 KDIPEGSFAK--SQQSRLEEEVASGSPFS--ITEERELPEGISTSSLEVVPE------NL 700
             +PE  F +   +    EEEV  G+P S  +TE   +P+  + S +E+  E       L
Sbjct: 359 --VPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPAL 416

Query: 701 NGSAILPTFENFTKKRKRKYELRYRKR 727
            G   +  F+   +  +  Y + YR +
Sbjct: 417 QGCRSVEEFQCLNRIEEGTYGVVYRAK 443


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 43/198 (21%), Positives = 93/198 (46%), Gaps = 13/198 (6%)

Query: 600 SAQKTELQDPHSLSELSSLKHSEDEEKPKIVNQ--ESLTESTSLKH-KLRNLEDKDIPEG 656
           S+ + +LQ      E    K ++ EE+ +I+ Q  E+L++ T ++H +L N     + E 
Sbjct: 782 SSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTEL 841

Query: 657 SFAKSQQSRLEEEVASGSPFSITEERELPEGISTSSLEVVPENLNGSAILPTFENFTKKR 716
              K ++  L  E+++       +  ++ + +  S  E   EN  G A +   E   K+ 
Sbjct: 842 QKVKMEKEALMTELSTVK----DKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKEL 897

Query: 717 KRKYELRYRKRPFNSENAKKAPDCLIKLLNQMQLFRLNKLERFQNLVLQELSSLKQDIQA 776
           K + +++        +  KK+ +   +  +Q++L    +L   Q  ++Q  ++LKQ+ + 
Sbjct: 898 KHQLQVQMENTLKEQKELKKSLEKEKEASHQLKL----ELNSMQEQLIQAQNTLKQNEKE 953

Query: 777 LEHLEKEVLEFWGKQSAD 794
            + L+  + E   KQS++
Sbjct: 954 EQQLQGNINEL--KQSSE 969



 Score = 38.5 bits (88), Expect = 0.025
 Identities = 129/607 (21%), Positives = 241/607 (39%), Gaps = 86/607 (14%)

Query: 216  DLARTLLTVGDYDQQVAISEALCRLTIKKSRDELVHKWFDDEVIAEAFKEIKDREFETDS 275
            DL + L  +GD DQ++   EAL  L   K    L+ K  +D      + +I+  E ET  
Sbjct: 510  DLEQVLRQIGDKDQKIQNLEAL--LQKSKENISLLEKERED-----LYAKIQAGEGETAV 562

Query: 276  RRFLNHLNNRLGDQRRVYSFPCIAAFADEHEMRKPADEKLEKFWIDFNLGSQSVTFYIDN 335
               L   N+ L +Q    +        ++ E  K A E L           Q    ++  
Sbjct: 563  LNQLQEKNHTLQEQVTQLT----EKLKNQSESHKQAQENLHD-------QVQEQKAHLRA 611

Query: 336  AENTLWDSVTLPKEAVMNFSITET-EKIKIFIIYLK-KPMIISYKEVMKIEIHFDLQFNI 393
            A++ +    T   E  +N  + E+ EK+    I +K K  ++   E  K     DLQ ++
Sbjct: 612  AQDRVLSLETSVNE--LNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHL 669

Query: 394  SQVSIQALGEDKQMLPDQTKISSELFSKSDK--EDRESPSGLERETEQAEESTNMVEFMS 451
               + Q   +DKQ   +  KI+++L   + K  + +E  S LE   ++ +E     +++S
Sbjct: 670  D--TAQNALQDKQQ--ELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKE-----KYLS 720

Query: 452  AEDDRCLITLHLNDQSEPPVIGEPASDSHLQPVPPFGVPDFPQQPKSHYRKHLFSESNQD 511
             E           ++ E  +    A    ++      + D  QQ + +        ++ +
Sbjct: 721  LEQK--------TEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLN--------TDLE 764

Query: 512  SSTSELSWTSNQKKKSLKSYSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLL-SPSEK 570
               +ELS     +K+ + S        TR +L+             E  + KL     EK
Sbjct: 765  LRATELSKQLEMEKEIVSS--------TRLDLQ-------KKSEALESIKQKLTKQEEEK 809

Query: 571  EIPEQN-NTTSPKTSEQKFQDSFAFLTAEDSAQKTELQDPHSLSELSSLKHSEDEEKPKI 629
            +I +Q+  T S +T  Q  + +    T     QK +++    ++ELS++K    +    +
Sbjct: 810  QILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSL 869

Query: 630  VNQESLTESTSLKHKLRNLE-DKDIPEGSFAKSQQSRLEEEVASGSPFSITEERELPEGI 688
             N +S  E  + K K   L+ +K   E       Q     +       S+ +E+E    +
Sbjct: 870  KNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQL 929

Query: 689  STSSLEVVPENLNGSAILPTFENFTKKRKRKYELRYRKRPFNSENAKKAPDCL-----IK 743
                  +  + +     L   E    K +++ +    +   +SE  KK  + L     I 
Sbjct: 930  KLELNSMQEQLIQAQNTLKQNE----KEEQQLQGNINELKQSSEQKKKQIEALQGELKIA 985

Query: 744  LLNQMQLFRLNKLERFQNLVLQELSSLKQDIQALEHLEKEVLE--------FWGKQSADL 795
            +L + +L   NKL++      QEL++ K+ I  L++  ++  E        F+G++S  L
Sbjct: 986  VLQKTEL--ENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELL 1043

Query: 796  QSFCDLQ 802
             +  DL+
Sbjct: 1044 ATRQDLK 1050


>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
          Length = 983

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 79/409 (19%), Positives = 152/409 (37%), Gaps = 62/409 (15%)

Query: 395 QVSIQALGEDKQMLPDQTKISSELFSKSDKEDRES--------PSGLERETEQAEESTNM 446
           +  I ++ E+K  L D T  +  L   S + D++          + L    ++ ++    
Sbjct: 316 KAEISSIRENKDRLSDSTTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQA 375

Query: 447 VEFMSAEDDRCLITLHLNDQSEPPVIGEPASDSHLQPVPPFGVPDFPQQPKSHYRKHLFS 506
                AE D    + H       P +G+P   S          PD    P         S
Sbjct: 376 KSPKEAEADLSFDSYHSTQTDLGPSLGKPGETSP---------PDSKSSPSVLIHSLGKS 426

Query: 507 ESNQDSSTSELSWTSNQKKKSLKSYSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLS 566
            ++ D    +L       +K L+S  + +K      L++            +  +A+L+ 
Sbjct: 427 TTDNDVRIQQLQEILQDLQKRLESSEAERK-----QLQV----------ELQSRRAELVC 471

Query: 567 PSEKEIPEQNNTTSPKTSE--QKFQDSFAFLTAEDSAQKTELQDPHSLSELSSLKHSE-D 623
            +  EI E ++  S K  E   K++++   + +     K  L  P S+   S        
Sbjct: 472 LNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVT 531

Query: 624 EEKPKIVNQE---SLTESTSLKHKLRNLEDK--DIPEGSFAKSQQSRLEEEVASGSPFSI 678
           EE+  ++ Q+   +L ES   K K+R LE+K  +  +G+  K      EE          
Sbjct: 532 EEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEE---------- 581

Query: 679 TEERELPEGISTSSLEVVPENLNGSAILPTFENFTKKRKRKYELRYRKRPFNSENAKKAP 738
                       SS   V EN+N       FE + + ++   +L+   +   ++ A    
Sbjct: 582 ----------MKSSYCSVIENMNKEKAF-LFEKYQEAQEEIMKLKDTLKSQMTQEASDEA 630

Query: 739 DCLIKLLNQMQLFRLNKLERFQNLVLQELSSLKQDIQALEHLEKEVLEF 787
           + + + +N+M +  LNK     + + +E  +  +D +  + LE    E+
Sbjct: 631 EDMKEAMNRM-IDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEY 678


>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
          Length = 972

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 79/409 (19%), Positives = 152/409 (37%), Gaps = 62/409 (15%)

Query: 395 QVSIQALGEDKQMLPDQTKISSELFSKSDKEDRES--------PSGLERETEQAEESTNM 446
           +  I ++ E+K  L D T  +  L   S + D++          + L    ++ ++    
Sbjct: 305 KAEISSIRENKDRLSDSTTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQA 364

Query: 447 VEFMSAEDDRCLITLHLNDQSEPPVIGEPASDSHLQPVPPFGVPDFPQQPKSHYRKHLFS 506
                AE D    + H       P +G+P   S          PD    P         S
Sbjct: 365 KSPKEAEADLSFDSYHSTQTDLGPSLGKPGETSP---------PDSKSSPSVLIHSLGKS 415

Query: 507 ESNQDSSTSELSWTSNQKKKSLKSYSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLS 566
            ++ D    +L       +K L+S  + +K      L++            +  +A+L+ 
Sbjct: 416 TTDNDVRIQQLQEILQDLQKRLESSEAERK-----QLQV----------ELQSRRAELVC 460

Query: 567 PSEKEIPEQNNTTSPKTSE--QKFQDSFAFLTAEDSAQKTELQDPHSLSELSSLKHSE-D 623
            +  EI E ++  S K  E   K++++   + +     K  L  P S+   S        
Sbjct: 461 LNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVT 520

Query: 624 EEKPKIVNQE---SLTESTSLKHKLRNLEDK--DIPEGSFAKSQQSRLEEEVASGSPFSI 678
           EE+  ++ Q+   +L ES   K K+R LE+K  +  +G+  K      EE          
Sbjct: 521 EEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEE---------- 570

Query: 679 TEERELPEGISTSSLEVVPENLNGSAILPTFENFTKKRKRKYELRYRKRPFNSENAKKAP 738
                       SS   V EN+N       FE + + ++   +L+   +   ++ A    
Sbjct: 571 ----------MKSSYCSVIENMNKEKAF-LFEKYQEAQEEIMKLKDTLKSQMTQEASDEA 619

Query: 739 DCLIKLLNQMQLFRLNKLERFQNLVLQELSSLKQDIQALEHLEKEVLEF 787
           + + + +N+M +  LNK     + + +E  +  +D +  + LE    E+
Sbjct: 620 EDMKEAMNRM-IDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEY 667


>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
          Length = 951

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 79/409 (19%), Positives = 152/409 (37%), Gaps = 62/409 (15%)

Query: 395 QVSIQALGEDKQMLPDQTKISSELFSKSDKEDRES--------PSGLERETEQAEESTNM 446
           +  I ++ E+K  L D T  +  L   S + D++          + L    ++ ++    
Sbjct: 284 KAEISSIRENKDRLSDSTTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQA 343

Query: 447 VEFMSAEDDRCLITLHLNDQSEPPVIGEPASDSHLQPVPPFGVPDFPQQPKSHYRKHLFS 506
                AE D    + H       P +G+P   S          PD    P         S
Sbjct: 344 KSPKEAEADLSFDSYHSTQTDLGPSLGKPGETSP---------PDSKSSPSVLIHSLGKS 394

Query: 507 ESNQDSSTSELSWTSNQKKKSLKSYSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLS 566
            ++ D    +L       +K L+S  + +K      L++            +  +A+L+ 
Sbjct: 395 TTDNDVRIQQLQEILQDLQKRLESSEAERK-----QLQV----------ELQSRRAELVC 439

Query: 567 PSEKEIPEQNNTTSPKTSE--QKFQDSFAFLTAEDSAQKTELQDPHSLSELSSLKHSE-D 623
            +  EI E ++  S K  E   K++++   + +     K  L  P S+   S        
Sbjct: 440 LNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVT 499

Query: 624 EEKPKIVNQE---SLTESTSLKHKLRNLEDK--DIPEGSFAKSQQSRLEEEVASGSPFSI 678
           EE+  ++ Q+   +L ES   K K+R LE+K  +  +G+  K      EE          
Sbjct: 500 EEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEE---------- 549

Query: 679 TEERELPEGISTSSLEVVPENLNGSAILPTFENFTKKRKRKYELRYRKRPFNSENAKKAP 738
                       SS   V EN+N       FE + + ++   +L+   +   ++ A    
Sbjct: 550 ----------MKSSYCSVIENMNKEKAF-LFEKYQEAQEEIMKLKDTLKSQMTQEASDEA 598

Query: 739 DCLIKLLNQMQLFRLNKLERFQNLVLQELSSLKQDIQALEHLEKEVLEF 787
           + + + +N+M +  LNK     + + +E  +  +D +  + LE    E+
Sbjct: 599 EDMKEAMNRM-IDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEY 646


>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 79/409 (19%), Positives = 152/409 (37%), Gaps = 62/409 (15%)

Query: 395 QVSIQALGEDKQMLPDQTKISSELFSKSDKEDRES--------PSGLERETEQAEESTNM 446
           +  I ++ E+K  L D T  +  L   S + D++          + L    ++ ++    
Sbjct: 313 KAEISSIRENKDRLSDSTTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQA 372

Query: 447 VEFMSAEDDRCLITLHLNDQSEPPVIGEPASDSHLQPVPPFGVPDFPQQPKSHYRKHLFS 506
                AE D    + H       P +G+P   S          PD    P         S
Sbjct: 373 KSPKEAEADLSFDSYHSTQTDLGPSLGKPGETSP---------PDSKSSPSVLIHSLGKS 423

Query: 507 ESNQDSSTSELSWTSNQKKKSLKSYSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLS 566
            ++ D    +L       +K L+S  + +K      L++            +  +A+L+ 
Sbjct: 424 TTDNDVRIQQLQEILQDLQKRLESSEAERK-----QLQV----------ELQSRRAELVC 468

Query: 567 PSEKEIPEQNNTTSPKTSE--QKFQDSFAFLTAEDSAQKTELQDPHSLSELSSLKHSE-D 623
            +  EI E ++  S K  E   K++++   + +     K  L  P S+   S        
Sbjct: 469 LNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVT 528

Query: 624 EEKPKIVNQE---SLTESTSLKHKLRNLEDK--DIPEGSFAKSQQSRLEEEVASGSPFSI 678
           EE+  ++ Q+   +L ES   K K+R LE+K  +  +G+  K      EE          
Sbjct: 529 EEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEE---------- 578

Query: 679 TEERELPEGISTSSLEVVPENLNGSAILPTFENFTKKRKRKYELRYRKRPFNSENAKKAP 738
                       SS   V EN+N       FE + + ++   +L+   +   ++ A    
Sbjct: 579 ----------MKSSYCSVIENMNKEKAF-LFEKYQEAQEEIMKLKDTLKSQMTQEASDEA 627

Query: 739 DCLIKLLNQMQLFRLNKLERFQNLVLQELSSLKQDIQALEHLEKEVLEF 787
           + + + +N+M +  LNK     + + +E  +  +D +  + LE    E+
Sbjct: 628 EDMKEAMNRM-IDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEY 675


>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 79/409 (19%), Positives = 152/409 (37%), Gaps = 62/409 (15%)

Query: 395 QVSIQALGEDKQMLPDQTKISSELFSKSDKEDRES--------PSGLERETEQAEESTNM 446
           +  I ++ E+K  L D T  +  L   S + D++          + L    ++ ++    
Sbjct: 313 KAEISSIRENKDRLSDSTTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQA 372

Query: 447 VEFMSAEDDRCLITLHLNDQSEPPVIGEPASDSHLQPVPPFGVPDFPQQPKSHYRKHLFS 506
                AE D    + H       P +G+P   S          PD    P         S
Sbjct: 373 KSPKEAEADLSFDSYHSTQTDLGPSLGKPGETSP---------PDSKSSPSVLIHSLGKS 423

Query: 507 ESNQDSSTSELSWTSNQKKKSLKSYSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLS 566
            ++ D    +L       +K L+S  + +K      L++            +  +A+L+ 
Sbjct: 424 TTDNDVRIQQLQEILQDLQKRLESSEAERK-----QLQV----------ELQSRRAELVC 468

Query: 567 PSEKEIPEQNNTTSPKTSE--QKFQDSFAFLTAEDSAQKTELQDPHSLSELSSLKHSE-D 623
            +  EI E ++  S K  E   K++++   + +     K  L  P S+   S        
Sbjct: 469 LNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVT 528

Query: 624 EEKPKIVNQE---SLTESTSLKHKLRNLEDK--DIPEGSFAKSQQSRLEEEVASGSPFSI 678
           EE+  ++ Q+   +L ES   K K+R LE+K  +  +G+  K      EE          
Sbjct: 529 EEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEE---------- 578

Query: 679 TEERELPEGISTSSLEVVPENLNGSAILPTFENFTKKRKRKYELRYRKRPFNSENAKKAP 738
                       SS   V EN+N       FE + + ++   +L+   +   ++ A    
Sbjct: 579 ----------MKSSYCSVIENMNKEKAF-LFEKYQEAQEEIMKLKDTLKSQMTQEASDEA 627

Query: 739 DCLIKLLNQMQLFRLNKLERFQNLVLQELSSLKQDIQALEHLEKEVLEF 787
           + + + +N+M +  LNK     + + +E  +  +D +  + LE    E+
Sbjct: 628 EDMKEAMNRM-IDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEY 675


>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 79/409 (19%), Positives = 152/409 (37%), Gaps = 62/409 (15%)

Query: 395 QVSIQALGEDKQMLPDQTKISSELFSKSDKEDRES--------PSGLERETEQAEESTNM 446
           +  I ++ E+K  L D T  +  L   S + D++          + L    ++ ++    
Sbjct: 313 KAEISSIRENKDRLSDSTTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQA 372

Query: 447 VEFMSAEDDRCLITLHLNDQSEPPVIGEPASDSHLQPVPPFGVPDFPQQPKSHYRKHLFS 506
                AE D    + H       P +G+P   S          PD    P         S
Sbjct: 373 KSPKEAEADLSFDSYHSTQTDLGPSLGKPGETSP---------PDSKSSPSVLIHSLGKS 423

Query: 507 ESNQDSSTSELSWTSNQKKKSLKSYSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLS 566
            ++ D    +L       +K L+S  + +K      L++            +  +A+L+ 
Sbjct: 424 TTDNDVRIQQLQEILQDLQKRLESSEAERK-----QLQV----------ELQSRRAELVC 468

Query: 567 PSEKEIPEQNNTTSPKTSE--QKFQDSFAFLTAEDSAQKTELQDPHSLSELSSLKHSE-D 623
            +  EI E ++  S K  E   K++++   + +     K  L  P S+   S        
Sbjct: 469 LNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVT 528

Query: 624 EEKPKIVNQE---SLTESTSLKHKLRNLEDK--DIPEGSFAKSQQSRLEEEVASGSPFSI 678
           EE+  ++ Q+   +L ES   K K+R LE+K  +  +G+  K      EE          
Sbjct: 529 EEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEE---------- 578

Query: 679 TEERELPEGISTSSLEVVPENLNGSAILPTFENFTKKRKRKYELRYRKRPFNSENAKKAP 738
                       SS   V EN+N       FE + + ++   +L+   +   ++ A    
Sbjct: 579 ----------MKSSYCSVIENMNKEKAF-LFEKYQEAQEEIMKLKDTLKSQMTQEASDEA 627

Query: 739 DCLIKLLNQMQLFRLNKLERFQNLVLQELSSLKQDIQALEHLEKEVLEF 787
           + + + +N+M +  LNK     + + +E  +  +D +  + LE    E+
Sbjct: 628 EDMKEAMNRM-IDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEY 675


>gi|48255931 hepatoma-derived growth factor-related protein 2
           isoform 1 [Homo sapiens]
          Length = 671

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 49/221 (22%), Positives = 83/221 (37%), Gaps = 6/221 (2%)

Query: 412 TKISSELFSKSDKEDRESPSGLERETEQAEESTNMVEFMSAED-DRCLITLHLNDQSEPP 470
           T  S  + S SD +     SGL+R+T   + S +     ++ D D+  ++    + SE  
Sbjct: 134 TAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSPSEEENSESS 193

Query: 471 VIGEPASDSHLQPVPPFGVPDFPQQPKSHYRKHLFSESNQDSSTSELSWTSNQKKKSLKS 530
              E  SD    P     V    + P    +K     ++   S ++      +     +S
Sbjct: 194 SESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARS 253

Query: 531 YSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLSPSEKEIPEQNNTTSPKTSEQKFQD 590
            SS   + + S+  +    PP      EK   K      K  PE+  ++S   S+    D
Sbjct: 254 ASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPK--PRGRKPKPERPPSSSSSDSDSDEVD 311

Query: 591 SFAFLTAEDSAQKTELQ---DPHSLSELSSLKHSEDEEKPK 628
             +     D A++ EL+         EL  L+  E EEK +
Sbjct: 312 RISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKER 352


>gi|14249158 hepatoma-derived growth factor-related protein 2
           isoform 2 [Homo sapiens]
          Length = 670

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 49/221 (22%), Positives = 83/221 (37%), Gaps = 6/221 (2%)

Query: 412 TKISSELFSKSDKEDRESPSGLERETEQAEESTNMVEFMSAED-DRCLITLHLNDQSEPP 470
           T  S  + S SD +     SGL+R+T   + S +     ++ D D+  ++    + SE  
Sbjct: 134 TAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSPSEEENSESS 193

Query: 471 VIGEPASDSHLQPVPPFGVPDFPQQPKSHYRKHLFSESNQDSSTSELSWTSNQKKKSLKS 530
              E  SD    P     V    + P    +K     ++   S ++      +     +S
Sbjct: 194 SESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARS 253

Query: 531 YSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLSPSEKEIPEQNNTTSPKTSEQKFQD 590
            SS   + + S+  +    PP      EK   K      K  PE+  ++S   S+    D
Sbjct: 254 ASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPK--PRGRKPKPERPPSSSSSDSDSDEVD 311

Query: 591 SFAFLTAEDSAQKTELQ---DPHSLSELSSLKHSEDEEKPK 628
             +     D A++ EL+         EL  L+  E EEK +
Sbjct: 312 RISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKER 352


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 103/473 (21%), Positives = 191/473 (40%), Gaps = 88/473 (18%)

Query: 344 VTLPKEAV---MNFSITETEKIKIFIIYLKKPMIISYKEVMKIEIHFDLQFNISQVSIQA 400
           +T  KEA+   ++  + E EKIK   +  K  +I   ++   +              I+ 
Sbjct: 312 LTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNL--------------IEQ 357

Query: 401 LGEDKQMLPDQTKISSELFSKSDKEDRESPSGLERETEQAEESTNMVEFMSAEDDRCLIT 460
           L +DK M+  +TK             R+    LE + E+  +  + ++ M+ + +     
Sbjct: 358 LEQDKGMVIAETK-------------RQMHETLEMKEEEIAQLRSRIKQMTTQGEE---- 400

Query: 461 LHLNDQSEPPVIGEPASDSHLQPVPPFGVPDFPQQPKSHYRKHLFSESNQDSSTSELSWT 520
             L +Q E     E A+   L+            Q     R+ L +E ++   T E   T
Sbjct: 401 --LREQKEK---SERAAFEELEKALSTA------QKTEEARRKLKAEMDEQIKTIEK--T 447

Query: 521 SNQKKKSLKSYSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLSPSEKEI--PEQNNT 578
           S +++ SL+   SR K        ++ V   SS    E+  AKL    EKE+   EQ  T
Sbjct: 448 SEEERISLQQELSRVKQE------VVDVMKKSS----EEQIAKLQKLHEKELARKEQELT 497

Query: 579 TSPKTSEQKFQDSFAFLTAEDSAQKTELQDPHSLSELSSLKHSEDEEKPKIVNQESLTES 638
              +T E++FQ+      A + +Q   L+      +  SL   E E + K +    LTES
Sbjct: 498 KKLQTREREFQEQMK--VALEKSQSEYLKISQEKEQQESLALEELELQKKAI----LTES 551

Query: 639 TSLKHKLRNLEDKDIPEGSFAKSQQSRLEEEVASGSPFSITEERELPEGISTSSLEVVPE 698
              ++KLR+L+ +       A++ ++R+  E+ S    S+ E +   + ++   LE    
Sbjct: 552 ---ENKLRDLQQE-------AETYRTRI-LELESSLEKSLQENKNQSKDLAV-HLEAEKN 599

Query: 699 NLNGSAILPTFENFTKKRKRKYE--------LRYRKRPFNSENAKKAPDCLIK---LLNQ 747
             N    +   ++ T+    K++        L+  K+ + +E  K    C  +   LL  
Sbjct: 600 KHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKD 659

Query: 748 MQLFRLNKLERFQNLVLQELSSLKQDIQALEHLEKEVLEFWGKQSADLQSFCD 800
            ++     +E      L++L   + ++++L     EVL+   K   +L    D
Sbjct: 660 KEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKD 712


>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           3 [Homo sapiens]
          Length = 526

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 45/185 (24%), Positives = 80/185 (43%), Gaps = 37/185 (20%)

Query: 553 SGSGHEKDQAKLLSPSEKEIPEQNNTTSPKTSEQKFQDSFAFLTAEDSAQKTELQDPHSL 612
           SGSG E+++       E+E  E+  +TS ++ E++ ++       E++   +E     S 
Sbjct: 30  SGSGSEEEE------EEEEEEEEEGSTSEESEEEEEEEEEE---EEETGSNSEEASEQSA 80

Query: 613 SELSSLKHSEDEEKPKIVNQESLTESTSLKHKLRNLEDKDIPEGSFAK--SQQSRLEEEV 670
            E+S  + SEDEE+    N+  L                 +PE  F +   +    EEEV
Sbjct: 81  EEVSEEEMSEDEERE---NENHLLV---------------VPESRFDRDSGESEEAEEEV 122

Query: 671 ASGSPFS--ITEERELPEGISTSSLEVVPE------NLNGSAILPTFENFTKKRKRKYEL 722
             G+P S  +TE   +P+  + S +E+  E       L G   +  F+   +  +  Y +
Sbjct: 123 GEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGV 182

Query: 723 RYRKR 727
            YR +
Sbjct: 183 VYRAK 187


>gi|190194423 SPARC-like 1 [Homo sapiens]
          Length = 664

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 55/280 (19%), Positives = 104/280 (37%), Gaps = 30/280 (10%)

Query: 378 KEVMKIEIHFDLQFNISQVSIQALGEDKQMLPDQTKISSELFSKSDKEDRESPSG----- 432
           + + K E + +   N S   +    +  Q L DQ     +    + +E+ E   G     
Sbjct: 155 ESITKREENQEQPRNYSHHQLNRSSKHSQGLRDQGNQEQDPNISNGEEEEEKEPGEVGTH 214

Query: 433 ---LERETEQAEESTNMVEFMSAEDDRCLITLHLNDQSEPPVIGEPASDSHLQPVPPFGV 489
               ER+TE   E  N  +    E+D       L +  +P  + +   D        F  
Sbjct: 215 NDNQERKTELPREHANSKQ----EEDNTQSDDILEESDQPTQVSKMQEDE-------FDQ 263

Query: 490 PDFPQQPKSHYRKHLFSESNQDSSTSELSWTSNQKKKSLKSYSSRKKTRTRSNLRILPVF 549
            +  Q+  S+      + SN +    E  W S + K  L++ S+ K+T  ++    L + 
Sbjct: 264 GNQEQEDNSNAEMEEENASNVNKHIQETEWQSQEGKTGLEAISNHKETEEKTVSEALLME 323

Query: 550 PPSSGSGHEKDQAKLLSPSEKEIPEQNNTTSPK--TSEQKFQDSFAFLTAEDSAQ----- 602
           P   G+   ++    +     +  +   T  P+   S+  F  S AFL AE +       
Sbjct: 324 PTDDGNTTPRNHG--VDDDGDDDGDDGGTDGPRHSASDDYFIPSQAFLEAERAQSIAYHL 381

Query: 603 --KTELQDPHSLSELSSLKHSEDEEKPKIVNQESLTESTS 640
             + + +  H    + + +  E +E  K  N  +  E++S
Sbjct: 382 KIEEQREKVHENENIGTTEPGEHQEAKKAENSSNEEETSS 421


>gi|190341024 SPARC-like 1 [Homo sapiens]
          Length = 664

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 55/280 (19%), Positives = 104/280 (37%), Gaps = 30/280 (10%)

Query: 378 KEVMKIEIHFDLQFNISQVSIQALGEDKQMLPDQTKISSELFSKSDKEDRESPSG----- 432
           + + K E + +   N S   +    +  Q L DQ     +    + +E+ E   G     
Sbjct: 155 ESITKREENQEQPRNYSHHQLNRSSKHSQGLRDQGNQEQDPNISNGEEEEEKEPGEVGTH 214

Query: 433 ---LERETEQAEESTNMVEFMSAEDDRCLITLHLNDQSEPPVIGEPASDSHLQPVPPFGV 489
               ER+TE   E  N  +    E+D       L +  +P  + +   D        F  
Sbjct: 215 NDNQERKTELPREHANSKQ----EEDNTQSDDILEESDQPTQVSKMQEDE-------FDQ 263

Query: 490 PDFPQQPKSHYRKHLFSESNQDSSTSELSWTSNQKKKSLKSYSSRKKTRTRSNLRILPVF 549
            +  Q+  S+      + SN +    E  W S + K  L++ S+ K+T  ++    L + 
Sbjct: 264 GNQEQEDNSNAEMEEENASNVNKHIQETEWQSQEGKTGLEAISNHKETEEKTVSEALLME 323

Query: 550 PPSSGSGHEKDQAKLLSPSEKEIPEQNNTTSPK--TSEQKFQDSFAFLTAEDSAQ----- 602
           P   G+   ++    +     +  +   T  P+   S+  F  S AFL AE +       
Sbjct: 324 PTDDGNTTPRNHG--VDDDGDDDGDDGGTDGPRHSASDDYFIPSQAFLEAERAQSIAYHL 381

Query: 603 --KTELQDPHSLSELSSLKHSEDEEKPKIVNQESLTESTS 640
             + + +  H    + + +  E +E  K  N  +  E++S
Sbjct: 382 KIEEQREKVHENENIGTTEPGEHQEAKKAENSSNEEETSS 421


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 67/327 (20%), Positives = 125/327 (38%), Gaps = 68/327 (20%)

Query: 417 ELFSKSDKEDRESPSGLERETEQAEESTNMVEFMSAEDDRCLITLHLNDQSEPPVIGEPA 476
           E   +  + +R+     + + EQ E      E     + R  ++ H     E     +  
Sbjct: 157 EQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED--YSDKV 214

Query: 477 SDSHLQPVPPFGVPDFPQQPKSHY-----RKHLFSESNQDSST-SELSWTSNQKKKSLKS 530
             SH    PP       + P+  +     RK +  E  ++    S+L   S+ ++K+  +
Sbjct: 215 KASHWSRSPP-------RPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSA 267

Query: 531 YSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLSPSEKEIPEQNNTTSPKTSEQKFQD 590
            SS  +                SGSG E+++       E+E  E+  +TS ++ E++ ++
Sbjct: 268 ESSSAE----------------SGSGSEEEE------EEEEEEEEEGSTSEESEEEEEEE 305

Query: 591 SFAFLTAEDSAQKTELQDPHSLSELSSLKHSEDEEKPKIVNQESLTESTSLKHKLRNLED 650
                  E++   +E     S  E+S  + SEDEE+    N+  L               
Sbjct: 306 EEE---EEETGSNSEEASEQSAEEVSEEEMSEDEERE---NENHLLV------------- 346

Query: 651 KDIPEGSFAK--SQQSRLEEEVASGSPFS--ITEERELPEGISTSSLEVVPE------NL 700
             +PE  F +   +    EEEV  G+P S  +TE   +P+  +   +E+  E       L
Sbjct: 347 --VPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPAL 404

Query: 701 NGSAILPTFENFTKKRKRKYELRYRKR 727
            G   +  F+   +  +  Y + YR +
Sbjct: 405 QGCRSVEEFQCLNRIEEGTYGVVYRAK 431


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 67/327 (20%), Positives = 125/327 (38%), Gaps = 68/327 (20%)

Query: 417 ELFSKSDKEDRESPSGLERETEQAEESTNMVEFMSAEDDRCLITLHLNDQSEPPVIGEPA 476
           E   +  + +R+     + + EQ E      E     + R  ++ H     E     +  
Sbjct: 167 EQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED--YSDKV 224

Query: 477 SDSHLQPVPPFGVPDFPQQPKSHY-----RKHLFSESNQDSST-SELSWTSNQKKKSLKS 530
             SH    PP       + P+  +     RK +  E  ++    S+L   S+ ++K+  +
Sbjct: 225 KASHWSRSPP-------RPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSA 277

Query: 531 YSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLSPSEKEIPEQNNTTSPKTSEQKFQD 590
            SS  +                SGSG E+++       E+E  E+  +TS ++ E++ ++
Sbjct: 278 ESSSAE----------------SGSGSEEEE------EEEEEEEEEGSTSEESEEEEEEE 315

Query: 591 SFAFLTAEDSAQKTELQDPHSLSELSSLKHSEDEEKPKIVNQESLTESTSLKHKLRNLED 650
                  E++   +E     S  E+S  + SEDEE+    N+  L               
Sbjct: 316 EEE---EEETGSNSEEASEQSAEEVSEEEMSEDEERE---NENHLLV------------- 356

Query: 651 KDIPEGSFAK--SQQSRLEEEVASGSPFS--ITEERELPEGISTSSLEVVPE------NL 700
             +PE  F +   +    EEEV  G+P S  +TE   +P+  +   +E+  E       L
Sbjct: 357 --VPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPAL 414

Query: 701 NGSAILPTFENFTKKRKRKYELRYRKR 727
            G   +  F+   +  +  Y + YR +
Sbjct: 415 QGCRSVEEFQCLNRIEEGTYGVVYRAK 441


>gi|31657123 Hermansky-Pudlak syndrome 5 isoform a [Homo sapiens]
          Length = 1129

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 65/241 (26%), Positives = 100/241 (41%), Gaps = 39/241 (16%)

Query: 414 ISSELFSKSDKEDRESPSGLERETEQAEESTNMVEFMSAED--DRCLITLHLNDQ--SEP 469
           ISS   S+SD++     S    E E+ +E T+  E    ED  D+C  + H N+   S  
Sbjct: 455 ISSRRGSQSDEDSCSLHSQTLSEDERFKEFTSQQE----EDLPDQCCGS-HGNEDNVSHA 509

Query: 470 PVIGEPASDSHLQPVPPFGVPDFPQQPKSHYRKHLFSESNQDSSTSELSWTSNQKKKSLK 529
           PV+ E   +   +   PFG+P   + P       L S      S S     + +K  +L 
Sbjct: 510 PVMFETDKN---ETFLPFGIPLPFRSPSP-----LVSLQAVKESVSSFVRKTTEKIGTL- 560

Query: 530 SYSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLSPSEKEIPEQNNTTSPKTSEQKFQ 589
                    T  +L++ P       S  E+D +    P E++  E+   TSP   E +FQ
Sbjct: 561 --------HTSPDLKVRPELRGDEQSC-EEDVSSDTCPKEEDTEEEKEVTSPPPEEDRFQ 611

Query: 590 DSFAFLTAEDSAQKTELQDPHSLSELSSLK--------HSEDEEKPKIVNQESLTESTSL 641
           +    L    +   T+LQDP  L E  SL+        H E     K  +  S T+++S+
Sbjct: 612 E----LKVATAEAMTKLQDPLVLFESESLRMVLQEWLSHLEKTFAMKDFSGVSDTDNSSM 667

Query: 642 K 642
           K
Sbjct: 668 K 668


>gi|31657125 Hermansky-Pudlak syndrome 5 isoform b [Homo sapiens]
          Length = 1015

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 65/241 (26%), Positives = 100/241 (41%), Gaps = 39/241 (16%)

Query: 414 ISSELFSKSDKEDRESPSGLERETEQAEESTNMVEFMSAED--DRCLITLHLNDQ--SEP 469
           ISS   S+SD++     S    E E+ +E T+  E    ED  D+C  + H N+   S  
Sbjct: 341 ISSRRGSQSDEDSCSLHSQTLSEDERFKEFTSQQE----EDLPDQCCGS-HGNEDNVSHA 395

Query: 470 PVIGEPASDSHLQPVPPFGVPDFPQQPKSHYRKHLFSESNQDSSTSELSWTSNQKKKSLK 529
           PV+ E   +   +   PFG+P   + P       L S      S S     + +K  +L 
Sbjct: 396 PVMFETDKN---ETFLPFGIPLPFRSPSP-----LVSLQAVKESVSSFVRKTTEKIGTL- 446

Query: 530 SYSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLSPSEKEIPEQNNTTSPKTSEQKFQ 589
                    T  +L++ P       S  E+D +    P E++  E+   TSP   E +FQ
Sbjct: 447 --------HTSPDLKVRPELRGDEQSC-EEDVSSDTCPKEEDTEEEKEVTSPPPEEDRFQ 497

Query: 590 DSFAFLTAEDSAQKTELQDPHSLSELSSLK--------HSEDEEKPKIVNQESLTESTSL 641
           +    L    +   T+LQDP  L E  SL+        H E     K  +  S T+++S+
Sbjct: 498 E----LKVATAEAMTKLQDPLVLFESESLRMVLQEWLSHLEKTFAMKDFSGVSDTDNSSM 553

Query: 642 K 642
           K
Sbjct: 554 K 554


>gi|31657127 Hermansky-Pudlak syndrome 5 isoform b [Homo sapiens]
          Length = 1015

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 65/241 (26%), Positives = 100/241 (41%), Gaps = 39/241 (16%)

Query: 414 ISSELFSKSDKEDRESPSGLERETEQAEESTNMVEFMSAED--DRCLITLHLNDQ--SEP 469
           ISS   S+SD++     S    E E+ +E T+  E    ED  D+C  + H N+   S  
Sbjct: 341 ISSRRGSQSDEDSCSLHSQTLSEDERFKEFTSQQE----EDLPDQCCGS-HGNEDNVSHA 395

Query: 470 PVIGEPASDSHLQPVPPFGVPDFPQQPKSHYRKHLFSESNQDSSTSELSWTSNQKKKSLK 529
           PV+ E   +   +   PFG+P   + P       L S      S S     + +K  +L 
Sbjct: 396 PVMFETDKN---ETFLPFGIPLPFRSPSP-----LVSLQAVKESVSSFVRKTTEKIGTL- 446

Query: 530 SYSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLSPSEKEIPEQNNTTSPKTSEQKFQ 589
                    T  +L++ P       S  E+D +    P E++  E+   TSP   E +FQ
Sbjct: 447 --------HTSPDLKVRPELRGDEQSC-EEDVSSDTCPKEEDTEEEKEVTSPPPEEDRFQ 497

Query: 590 DSFAFLTAEDSAQKTELQDPHSLSELSSLK--------HSEDEEKPKIVNQESLTESTSL 641
           +    L    +   T+LQDP  L E  SL+        H E     K  +  S T+++S+
Sbjct: 498 E----LKVATAEAMTKLQDPLVLFESESLRMVLQEWLSHLEKTFAMKDFSGVSDTDNSSM 553

Query: 642 K 642
           K
Sbjct: 554 K 554


>gi|11225260 DNA topoisomerase I [Homo sapiens]
          Length = 765

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 51/261 (19%), Positives = 98/261 (37%), Gaps = 21/261 (8%)

Query: 501 RKHLFSESNQDSSTSELSWTSNQKKKSLKSYSSRKKTRTRSNLRILPVFPPSSGSGHEKD 560
           R+H   E  ++    +   ++++ K S K +  ++KT+ +                 ++ 
Sbjct: 31  REHRHKEHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRK 90

Query: 561 QAKLLSPSEKEIPEQNN---TTSPKTSEQKFQDSFAFLTAEDSAQKTELQDPHSLSELSS 617
           + K+ +  + +I ++     ++ P+  ++   D +     ED       +D         
Sbjct: 91  EEKVRASGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPK 150

Query: 618 LKHSEDEEKPKIVNQESLTESTSLKHKLRNLEDKDIPEGSFAKSQQSRLEEEVASGSPFS 677
              +ED +K K    E   E   LK      +DK +PE    K +  + EE+      + 
Sbjct: 151 KIKTEDTKKEKKRKLEE-EEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQ-----KWK 204

Query: 678 ITEERELPEGISTSSLEVVPENLNGSAILPTFENFTKKRKRKYELRYRKRPFNSENAKKA 737
             EE   PEGI    LE       G    P +E   +  K  Y+ +  K    S  A++ 
Sbjct: 205 WWEEERYPEGIKWKFLE-----HKGPVFAPPYEPLPENVKFYYDGKVMKL---SPKAEEV 256

Query: 738 PDCLIKLLNQ----MQLFRLN 754
                K+L+      ++FR N
Sbjct: 257 ATFFAKMLDHEYTTKEIFRKN 277


>gi|109637791 transcription factor-like nuclear regulator [Homo
           sapiens]
          Length = 2624

 Score = 40.8 bits (94), Expect = 0.005
 Identities = 64/291 (21%), Positives = 108/291 (37%), Gaps = 42/291 (14%)

Query: 468 EPPVIGEPASDSHLQPVPPFGVP--DF----PQQPKSHYRKHLFSESNQDSSTSELSWTS 521
           E P   +PA+DS  +P  P  VP  DF    PQ+             N    +S  S T 
Sbjct: 32  ESPRPPDPATDSASKPAEPTDVPTVDFGGAEPQEKAPRSSTEKTGGDNDVEESSRSSSTV 91

Query: 522 NQKKKSLKSYSSRKKTRTRSNLRILPVFPPSSGSGHEKDQAKLLSPSEKEIPEQNNTTSP 581
           +Q++K + S SS  K    S++ +     P S    E  Q    S  EK+        S 
Sbjct: 92  SQRRKRISSTSSLVK----SSVSVPSESHPLSTINQEAPQPTATSTKEKQ------PCSD 141

Query: 582 KTSEQKFQDSFAFLTAEDSAQKTELQDPHSLSE-----------LSSLKHSEDEEKP--K 628
           +    K Q     L  E   +K + ++ ++++E           +    +   +  P   
Sbjct: 142 RYRIYKAQKLREMLKEELRKEKKQWKNKYAINESQRPPDRSKMTMRDFIYYLPDNNPMTS 201

Query: 629 IVNQESLTESTSLKHKLRNLEDKDIPEGSFAKSQQSRLEEEVASGSPFSITEERELPEG- 687
            + QE  TE  S   + R  E K  P      ++ + +EEE   G P  +   +   +G 
Sbjct: 202 SLEQEKKTEKPSTPVQTREQEGKSTP-----NAEDNEMEEETDDG-PLLVPRVKVAEDGS 255

Query: 688 --ISTSSLEVVPENLNGSAIL----PTFENFTKKRKRKYELRYRKRPFNSE 732
             +   SL V      G  ++    P FE  +      +   Y  +P++++
Sbjct: 256 IILDEESLTVEVLRTKGPCVVEENDPIFERGSTTTYSSFRKNYYSKPWSNK 306


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.366 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,584,254
Number of Sequences: 37866
Number of extensions: 1376258
Number of successful extensions: 5563
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 261
Number of HSP's that attempted gapping in prelim test: 5274
Number of HSP's gapped (non-prelim): 536
length of query: 812
length of database: 18,247,518
effective HSP length: 111
effective length of query: 701
effective length of database: 14,044,392
effective search space: 9845118792
effective search space used: 9845118792
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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