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Search of human proteins with 93204867
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|93204867 G protein-coupled receptor 158 [Homo sapiens]
(1215 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|93204867 G protein-coupled receptor 158 [Homo sapiens] 2462 0.0
gi|93352554 GPR158-like 1 [Homo sapiens] 713 0.0
gi|239751284 PREDICTED: hypothetical protein XP_002347797 [Homo ... 160 9e-39
gi|46358417 glutamate receptor, metabotropic 3 precursor [Homo s... 56 2e-07
gi|166999223 glutamate receptor, metabotropic 1 isoform beta pre... 56 2e-07
gi|166999098 glutamate receptor, metabotropic 1 isoform alpha pr... 56 2e-07
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 55 3e-07
gi|219842343 glutamate receptor, metabotropic 5 isoform a precur... 55 4e-07
gi|4504143 glutamate receptor, metabotropic 5 isoform b precurso... 54 7e-07
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 54 9e-07
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 54 9e-07
gi|87299628 biorientation of chromosomes in cell division 1-like... 54 1e-06
gi|66529100 glutamate receptor, metabotropic 2 isoform a precurs... 50 1e-05
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 50 1e-05
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 50 2e-05
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 48 6e-05
gi|58082089 hypothetical protein LOC161394 [Homo sapiens] 47 8e-05
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 47 1e-04
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 47 1e-04
gi|40255245 G protein-coupled receptor 51 [Homo sapiens] 46 2e-04
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 45 4e-04
gi|62241003 cardiomyopathy associated 5 [Homo sapiens] 45 4e-04
gi|4504141 glutamate receptor, metabotropic 4 [Homo sapiens] 45 5e-04
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 45 5e-04
gi|194306543 oxidation resistance 1 isoform 2 [Homo sapiens] 45 5e-04
gi|194306541 oxidation resistance 1 isoform 1 [Homo sapiens] 45 5e-04
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 44 7e-04
gi|217330641 IWS1 homolog [Homo sapiens] 44 0.001
gi|187960069 glutamate receptor, metabotropic 8 isoform b precur... 43 0.002
gi|187960067 glutamate receptor, metabotropic 8 isoform a precur... 43 0.002
>gi|93204867 G protein-coupled receptor 158 [Homo sapiens]
Length = 1215
Score = 2462 bits (6380), Expect = 0.0
Identities = 1215/1215 (100%), Positives = 1215/1215 (100%)
Query: 1 MGAMAYPLLLCLLLAQLGLGAVGASRDPQGRPDSPRERTPKGKPHAQQPGRASASDSSAP 60
MGAMAYPLLLCLLLAQLGLGAVGASRDPQGRPDSPRERTPKGKPHAQQPGRASASDSSAP
Sbjct: 1 MGAMAYPLLLCLLLAQLGLGAVGASRDPQGRPDSPRERTPKGKPHAQQPGRASASDSSAP 60
Query: 61 WSRSTDGTILAQKLAEEVPMDVASYLYTGDSHQLKRANCSGRYELAGLPGKWPALASAHP 120
WSRSTDGTILAQKLAEEVPMDVASYLYTGDSHQLKRANCSGRYELAGLPGKWPALASAHP
Sbjct: 61 WSRSTDGTILAQKLAEEVPMDVASYLYTGDSHQLKRANCSGRYELAGLPGKWPALASAHP 120
Query: 121 SLHRALDTLTHATNFLNVMLQSNKSREQNLQDDLDWYQALVWSLLEGEPSISRAAITFST 180
SLHRALDTLTHATNFLNVMLQSNKSREQNLQDDLDWYQALVWSLLEGEPSISRAAITFST
Sbjct: 121 SLHRALDTLTHATNFLNVMLQSNKSREQNLQDDLDWYQALVWSLLEGEPSISRAAITFST 180
Query: 181 DSLSAPAPQVFLQATREESRILLQDLSSSAPHLANATLETEWFHGLRRKWRPHLHRRGPN 240
DSLSAPAPQVFLQATREESRILLQDLSSSAPHLANATLETEWFHGLRRKWRPHLHRRGPN
Sbjct: 181 DSLSAPAPQVFLQATREESRILLQDLSSSAPHLANATLETEWFHGLRRKWRPHLHRRGPN 240
Query: 241 QGPRGLGHSWRRKDGLGGDKSHFKWSPPYLECENGSYKPGWLVTLSSAIYGLQPNLVPEF 300
QGPRGLGHSWRRKDGLGGDKSHFKWSPPYLECENGSYKPGWLVTLSSAIYGLQPNLVPEF
Sbjct: 241 QGPRGLGHSWRRKDGLGGDKSHFKWSPPYLECENGSYKPGWLVTLSSAIYGLQPNLVPEF 300
Query: 301 RGVMKVDINLQKVDIDQCSSDGWFSGTHKCHLNNSECMPIKGLGFVLGAYECICKAGFYH 360
RGVMKVDINLQKVDIDQCSSDGWFSGTHKCHLNNSECMPIKGLGFVLGAYECICKAGFYH
Sbjct: 301 RGVMKVDINLQKVDIDQCSSDGWFSGTHKCHLNNSECMPIKGLGFVLGAYECICKAGFYH 360
Query: 361 PGVLPVNNFRRRGPDQHISGSTKDVSEEAYVCLPCREGCPFCADDSPCFVQEDKYLRLAI 420
PGVLPVNNFRRRGPDQHISGSTKDVSEEAYVCLPCREGCPFCADDSPCFVQEDKYLRLAI
Sbjct: 361 PGVLPVNNFRRRGPDQHISGSTKDVSEEAYVCLPCREGCPFCADDSPCFVQEDKYLRLAI 420
Query: 421 ISFQALCMLLDFVSMLVVYHFRKAKSIRASGLILLETILFGSLLLYFPVVILYFEPSTFR 480
ISFQALCMLLDFVSMLVVYHFRKAKSIRASGLILLETILFGSLLLYFPVVILYFEPSTFR
Sbjct: 421 ISFQALCMLLDFVSMLVVYHFRKAKSIRASGLILLETILFGSLLLYFPVVILYFEPSTFR 480
Query: 481 CILLRWARLLGFATVYGTVTLKLHRVLKVFLSRTAQRIPYMTGGRVMRMLAVILLVVFWF 540
CILLRWARLLGFATVYGTVTLKLHRVLKVFLSRTAQRIPYMTGGRVMRMLAVILLVVFWF
Sbjct: 481 CILLRWARLLGFATVYGTVTLKLHRVLKVFLSRTAQRIPYMTGGRVMRMLAVILLVVFWF 540
Query: 541 LIGWTSSVCQNLEKQISLIGQGKTSDHLIFNMCLIDRWDYMTAVAEFLFLLWGVYLCYAV 600
LIGWTSSVCQNLEKQISLIGQGKTSDHLIFNMCLIDRWDYMTAVAEFLFLLWGVYLCYAV
Sbjct: 541 LIGWTSSVCQNLEKQISLIGQGKTSDHLIFNMCLIDRWDYMTAVAEFLFLLWGVYLCYAV 600
Query: 601 RTVPSAFHEPRYMAVAVHNELIISAIFHTIRFVLASRLQSDWMLMLYFAHTHLTVTVTIG 660
RTVPSAFHEPRYMAVAVHNELIISAIFHTIRFVLASRLQSDWMLMLYFAHTHLTVTVTIG
Sbjct: 601 RTVPSAFHEPRYMAVAVHNELIISAIFHTIRFVLASRLQSDWMLMLYFAHTHLTVTVTIG 660
Query: 661 LLLIPKFSHSSNNPRDDIATEAYEDELDMGRSGSYLNSSINSAWSEHSLDPEDIRDELKK 720
LLLIPKFSHSSNNPRDDIATEAYEDELDMGRSGSYLNSSINSAWSEHSLDPEDIRDELKK
Sbjct: 661 LLLIPKFSHSSNNPRDDIATEAYEDELDMGRSGSYLNSSINSAWSEHSLDPEDIRDELKK 720
Query: 721 LYAQLEIYKRKKMITNNPHLQKKRCSKKGLGRSIMRRITEIPETVSRQCSKEDKEGADHG 780
LYAQLEIYKRKKMITNNPHLQKKRCSKKGLGRSIMRRITEIPETVSRQCSKEDKEGADHG
Sbjct: 721 LYAQLEIYKRKKMITNNPHLQKKRCSKKGLGRSIMRRITEIPETVSRQCSKEDKEGADHG 780
Query: 781 TAKGTALIRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQE 840
TAKGTALIRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQE
Sbjct: 781 TAKGTALIRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQE 840
Query: 841 EETTENSTLESLSGKKLTQKLKEDSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQ 900
EETTENSTLESLSGKKLTQKLKEDSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQ
Sbjct: 841 EETTENSTLESLSGKKLTQKLKEDSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQ 900
Query: 901 KSLSVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQN 960
KSLSVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQN
Sbjct: 901 KSLSVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQN 960
Query: 961 SNPAEEPRKPQKSGIMKQQRVNPTTANSDLNPGTTQMKDNFDIGEVCPWEVYDLTPGPVP 1020
SNPAEEPRKPQKSGIMKQQRVNPTTANSDLNPGTTQMKDNFDIGEVCPWEVYDLTPGPVP
Sbjct: 961 SNPAEEPRKPQKSGIMKQQRVNPTTANSDLNPGTTQMKDNFDIGEVCPWEVYDLTPGPVP 1020
Query: 1021 SESKVQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQQSNQKRIDKAEVCLWESQGQS 1080
SESKVQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQQSNQKRIDKAEVCLWESQGQS
Sbjct: 1021 SESKVQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQQSNQKRIDKAEVCLWESQGQS 1080
Query: 1081 ILEDEKLLISKTPVLPERAKEENGGQPRAANVCAGQSEELPPKAVASKTENENLNQIGHQ 1140
ILEDEKLLISKTPVLPERAKEENGGQPRAANVCAGQSEELPPKAVASKTENENLNQIGHQ
Sbjct: 1081 ILEDEKLLISKTPVLPERAKEENGGQPRAANVCAGQSEELPPKAVASKTENENLNQIGHQ 1140
Query: 1141 EKKTSSSEENVRGSYNSSNNFQQPLTSRAEVCPWEFETPAQPNAGRSVALPASSALSANK 1200
EKKTSSSEENVRGSYNSSNNFQQPLTSRAEVCPWEFETPAQPNAGRSVALPASSALSANK
Sbjct: 1141 EKKTSSSEENVRGSYNSSNNFQQPLTSRAEVCPWEFETPAQPNAGRSVALPASSALSANK 1200
Query: 1201 IAGPRKEEIWDSFKV 1215
IAGPRKEEIWDSFKV
Sbjct: 1201 IAGPRKEEIWDSFKV 1215
>gi|93352554 GPR158-like 1 [Homo sapiens]
Length = 2367
Score = 713 bits (1840), Expect = 0.0
Identities = 437/1062 (41%), Positives = 588/1062 (55%), Gaps = 131/1062 (12%)
Query: 77 EVPMDVA----SYLYTGDSHQLKRANCSGRYELAGLPGKWPALASAHPSLHRALDTLTHA 132
+VP++ A +YLY+GD+ QL + NCS RYE G G P L PSL A TL A
Sbjct: 50 QVPLEGAEAALAYLYSGDAQQLSQVNCSERYEARGA-GAMPGLP---PSLQGAAGTLAQA 105
Query: 133 TNFLNVMLQSNKSREQNLQDDLDWYQALVWSLLEGEPSISRAAITFSTDSLSAPAPQVFL 192
NFLN++LQ+N RE ++++D++WYQALV S+ EG+P + RA +TF+ A Q+ L
Sbjct: 106 ANFLNMLLQANDIRESSVEEDVEWYQALVRSVAEGDPRVYRALLTFNPPP-GASHLQLAL 164
Query: 193 QATREESRILLQDLSSSAPHLANATLETEWFHGLRRKWRPHLHRRGPNQGPRGLGH-SWR 251
QATR +LQDLS + N + + P L +R LG W
Sbjct: 165 QATRTGEETILQDLSGNWVQEENPPGDLD---------TPALKKRVLTNDLGSLGSPKWP 215
Query: 252 RKDGLGGDKSHFKWSPPYLECENGSYKPGWLVTLSSAIYGLQPNLVPEFRGVMKVDINLQ 311
+ DG GD + SPP+LEC+ G +PGWL+TLS+ YGL+P+L PE RG +++D++LQ
Sbjct: 216 QADGYVGDTQQVRLSPPFLECQEGRLRPGWLITLSATFYGLKPDLSPEVRGQVQMDVDLQ 275
Query: 312 KVDIDQCSSD-GWFSGTHKCHLNNSECMPIKGLGFVLGAYECICKAGFYHP---GVLPVN 367
VDI+QC+S GW+S TH C LN+++C+P++ GFVLG Y C C+ GFY G L +
Sbjct: 276 SVDINQCASGPGWYSNTHLCDLNSTQCVPLESQGFVLGRYLCRCRPGFYGASPSGGLEES 335
Query: 368 NFRRRGPDQHISGSTKDVSEEAYVCLPCREGCPFCADDSPCFVQEDKYLRLAIISFQALC 427
+F+ G G + S CLPC EGC C D +PC V+E LR A+++ QA C
Sbjct: 336 DFQTTGQ----FGFPEGRSGRLLQCLPCPEGCTSCMDATPCLVEEAAVLRAAVLACQACC 391
Query: 428 MLLDFVSMLVVYHFRKAKSIRASGLILLETILFGSLLLYFPVVILYFEPSTFRCILLRWA 487
ML F+SMLV Y R+ K I ASG++LLET+LFG LLLYFPV ILYF+PS FRCI LRW
Sbjct: 392 MLAIFLSMLVSYRCRRNKRIWASGVVLLETVLFGFLLLYFPVFILYFKPSVFRCIALRWV 451
Query: 488 RLLGFATVYGTVTLKLHRVLKVFLSRTAQRIPYMTGGRVMRMLAVILLVVFWFLIGWTSS 547
RLLGFA VYGT+ LKL+RVL++FLSRTAQR ++ GR++R L ++LL V FL WT
Sbjct: 452 RLLGFAIVYGTIILKLYRVLQLFLSRTAQRSALLSSGRLLRRLGLLLLPVLGFLAVWTVG 511
Query: 548 VCQNLEKQISLIGQGKTSDHLIFNMCLIDRWDYMTAVAEFLFLLWGVYLCYAVRTVPSAF 607
+ + L+ +G T F +C DRWDY+ VAE L L WG +LCYA R V SAF
Sbjct: 512 ALERGIQHAPLVIRGHTPSGRHFYLCHHDRWDYIMVVAELLLLCWGSFLCYATRAVLSAF 571
Query: 608 HEPRYMAVAVHNELIISAIFHTIRFVLASRLQSDWMLMLYFAHTHLTVTVTIGLLLIPKF 667
HEPRYM +A+HNEL++SA FHT RFVL L DW L+L+F HTH TVT T+ L+ IPKF
Sbjct: 572 HEPRYMGIALHNELLLSAAFHTARFVLVPSLHPDWTLLLFFFHTHSTVTTTLALIFIPKF 631
Query: 668 SHSSNNPRDDIATEAYEDELDMGRSGSYLNSSINSAWSEHSLDPEDIRDELKKLYAQLEI 727
PR+++ E EDELD+ SGSYL SSI SAWSEHSLDP DIRDELKKLYAQLE+
Sbjct: 632 WKLGAPPREEMVDEVCEDELDLQHSGSYLGSSIASAWSEHSLDPGDIRDELKKLYAQLEV 691
Query: 728 YKRKKMITNNPHLQKKRCSK-KGLGRSIMRRITEIPETVSRQCSKEDKEGADHGTAKGTA 786
+K K+M NNPHL KKR S +GLGRS MR + E PE ++RQ S+ D HG+ G++
Sbjct: 692 HKTKEMAANNPHLPKKRGSSCQGLGRSFMRYLAEFPEALARQHSR-DSGSPGHGSLPGSS 750
Query: 787 ---LIRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQEEET 843
L+ + E G +L KS STYD R+Q
Sbjct: 751 RRRLLSSSLQEPEGTP-------------ALHKSRSTYDQRREQ---------------- 781
Query: 844 TENSTLESLSGKKLTQKLKEDSEAESTESVP-LVCKSASAHNLSSEKKTGHPRTSMLQKS 902
+ L+SL +KL +K ES E P L +SASAHNL+ ++ R + LQKS
Sbjct: 782 -DPPLLDSLLRRKLAKKASRTESRESVEGPPALGFRSASAHNLTVGERLPRARPASLQKS 840
Query: 903 LSVIASAKEKTLGLAGKT-------QTAGVEERTK------------------------- 930
LSV AS++EK L +A + Q EER K
Sbjct: 841 LSV-ASSREKALLMASQAYLEETYRQAKEREERKKAKAAMASLVRRPSARRLERPRGAPL 899
Query: 931 SQKPLP-KDKETNRNHSNS---DNTETKDPAPQNSNPAEEPRKPQKSGIMKQQRVNPT-- 984
S P P K + +H++ + + P P + P G+ + + ++PT
Sbjct: 900 SAPPSPAKSSSVDSSHTSGRLHEEARRRLPHPPIRHQVSTPILALSGGLGEPRMLSPTST 959
Query: 985 -----------TANSDLNPGTTQMKDNFDIGEVCPWEVYDLTP----------------- 1016
T L P + + +CPWE +L
Sbjct: 960 LAPALLPALAPTPAPALAPVPVSPQSPNLLTYICPWENAELPAKQENVPQEGPSGPERGH 1019
Query: 1017 -GPVPSESKVQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEV 1057
P P+ +++ + +S+ + E +HH+ +A +V
Sbjct: 1020 HSPAPARARLWRALSVAVEKSRAGENEMDAEDAHHQREANDV 1061
Score = 51.2 bits (121), Expect = 6e-06
Identities = 106/476 (22%), Positives = 165/476 (34%), Gaps = 125/476 (26%)
Query: 741 QKKRCSKKG----LGRSIMRRITEIPETVSRQCSKEDKEGADHGTAKGTALIRKNPPESS 796
Q+++ +KG LG + + + ++ + C E+K+ + + S
Sbjct: 1842 QREKALEKGRLTSLGEDVSKGMAKLCQQQETICIWENKDLRESPAQAPKISDLPSSMSSE 1901
Query: 797 GNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQEEETTENSTLESLSGKK 856
G S E T K + K+ S +H+ T+E + P EE TTE+ G+K
Sbjct: 1902 VAEGHSLEATEKGDLRQDPKTGSFPEHI---TQEKA--PAADTEEFTTED-------GEK 1949
Query: 857 LTQKLKEDSEAESTESVPLVCKSASAHNLS--SEKKTGHPRTSMLQKSLSVIASAKEKTL 914
+ +L+ E+T A A ++S ++ P+ S S ++++
Sbjct: 1950 TSHELQSVCPWETT---------APADSVSHLDRQRPDQPKAS----SQRLVSTGGRAAD 1996
Query: 915 GLAGKTQTAGVEERTKSQKP----------LPKDKETNRNHSNSDNTETKDPAPQNSNPA 964
AGV + S K +P K +R D+ E K AP+ S P
Sbjct: 1997 VCPWDVPDAGVYKSDSSAKAETCPWEVTERIPV-KGVSRQDGKGDSQEEKGRAPEKSEPK 2055
Query: 965 EEP--RKPQKSGIMKQQRVNPTTANSDLNPGTTQMKDNFDIGEVCPWEVYD---LTPGPV 1019
P +KP+ + +Q+ V CPWE D L+P P
Sbjct: 2056 GVPVQKKPEMADFRQQEAV-------------------------CPWESQDGKGLSPQPA 2090
Query: 1020 PSESKVQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVC--QQSNQKRIDKAEVCLWESQ 1077
P S + S A +E + AEVC + KAE+C WE+
Sbjct: 2091 PDASDRSRGSSEAAGSVET--------------RVAEVCLWEVVEAPSAKKAEICPWEAG 2136
Query: 1078 GQSILEDEKLLISKTPVLPERAKEENGGQPRAANVCAGQSEELPPKAVASKTENEN---- 1133
G + E E + + + G+ G +EE KA A E E
Sbjct: 2137 GGAAEEGE-----------QERESQGQGEMFLQKAGPGGTEEHFSKAAAKPREQEAVCPG 2185
Query: 1134 --------LNQIG--HQEKKTSSSEENVRGSYNSSNNFQQPLTSRAEVCPWEFETP 1179
L Q G E K S E GS AE+C WE P
Sbjct: 2186 EGTGSGGLLPQSGALDPELKVSPKEAGSMGS------------RMAELCQWEITDP 2229
Score = 50.4 bits (119), Expect = 1e-05
Identities = 104/527 (19%), Positives = 187/527 (35%), Gaps = 71/527 (13%)
Query: 665 PKFSHSSNNPRDDIATEAYEDELDMGRSGSYLNSSINSAWSEHSLDPEDIRDELKKLYAQ 724
P+ H S P A ++ R+G + +++ + H + D+ ++ K++ +
Sbjct: 1015 PERGHHSPAPARARLWRALSVAVEKSRAGE---NEMDAEDAHHQREANDVDEDRPKIFPK 1071
Query: 725 LEIYKRKKMITNNPHLQKKRCSKKGLGRSIMRRITEIPETVSRQCSKEDKEGADHGTAKG 784
K ++G RS+ I + + S KE E + G G
Sbjct: 1072 SHSLKAPV--------------QQGSMRSLGLAIKALTRSRSTYREKESVEESPEGQNSG 1117
Query: 785 TALIRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQEEETT 844
TA P S G+ K + + + S + Q +S + Q E +
Sbjct: 1118 TAGESMGAPSRSPRLGRPKAVSKQAALIPSDDKESLQNQ---QNAHTSRMLQVCQREGSR 1174
Query: 845 ENSTLESLSGKKLTQKLKE-DSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQKSL 903
E G+++TQ L E +E + ++ + + N+ K+T + + L
Sbjct: 1175 EQED----RGRRMTQGLGERKAERAGKTGLAMLRQVSRDKNIKQSKETPVGWQELPKAGL 1230
Query: 904 SVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQNSNP 963
+ SA + + E T+S+ P + N + ET + AP++
Sbjct: 1231 QSLGSADHRVAEVCPW-------EVTESETRQPD----SGNKAEICPWETSEGAPESRAL 1279
Query: 964 AEEPRKPQKSGIMKQQRVNPTTANSDLNPGTTQMKDNF--DIGEVCPWEVYD---LTPGP 1018
++P QK K+ + D+ P + + + VCPWE D L+PG
Sbjct: 1280 RQDPGDSQK----KRGEARGKSEPIDVVPMMRKKPERLVREQEAVCPWESADRGGLSPGS 1335
Query: 1019 VPSE-----SKVQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQQSNQKRIDKAEVCL 1073
P + K + S+ A ++EK P + H P I KAE C
Sbjct: 1336 APQDPGRIRDKSEAGDSVEARKVEK-PGWEAAGPEAHTPD------------ITKAEPCP 1382
Query: 1074 WESQGQSILEDEKLLISKTPVLPERAKEENGGQPRAANVCAGQSEELPPKAVASKTENEN 1133
WE+ ED K LP+ ++ G E L P T+
Sbjct: 1383 WEASEGG--EDGKPAQEAVKDLPQEKQKTRKATFWKEQKPGGDLESLCPW---ESTDFRG 1437
Query: 1134 LNQIGHQEKKTSSSEENVRGSYNSSNNFQQ---PLTSRAEVCPWEFE 1177
+ + Q +S ++ ++ P +AE+CPWE +
Sbjct: 1438 PSAVSIQAPGSSECSGSLGSGIAEVCLWEAGDAPAIQKAEICPWELD 1484
Score = 46.2 bits (108), Expect = 2e-04
Identities = 101/486 (20%), Positives = 174/486 (35%), Gaps = 61/486 (12%)
Query: 748 KGLGRSIMRRITEIPETVSRQCSKEDKEGADHGTAKGTALIRKNPPESSGNTGKSKEETL 807
+GLG R + + RQ S++ T G + K +S G+
Sbjct: 1185 QGLGERKAERAGKTGLAMLRQVSRDKNIKQSKETPVGWQELPKAGLQSLGSAD------- 1237
Query: 808 KNRVFSLKKSHSTYDHVR--DQTEESSSLPTESQEEETTENSTLESLSGKKLTQKLKEDS 865
+RV + T R D ++ P E+ E E+ L G ++ +
Sbjct: 1238 -HRVAEVCPWEVTESETRQPDSGNKAEICPWETSEG-APESRALRQDPGDSQKKRGEARG 1295
Query: 866 EAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQKSLSVIASAKEKTLGLAGKTQTAGV 925
++E + VP++ K L E++ P S + LS SA + + K++
Sbjct: 1296 KSEPIDVVPMMRKKPE--RLVREQEAVCPWESADRGGLSP-GSAPQDPGRIRDKSEAGDS 1352
Query: 926 EERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQNSNPAEEPRKPQKSGI----MKQQRV 981
E K +KP E +++ + +P P ++ E KP + + ++Q+
Sbjct: 1353 VEARKVEKP---GWEAAGPEAHTPDITKAEPCPWEASEGGEDGKPAQEAVKDLPQEKQKT 1409
Query: 982 NPTTANSDLNPGTTQMKDNFDIGEVCPWEVYDLTPGPVPSESKVQKHVSIVASEMEKNPT 1041
T + PG D+ +CPWE D PS +Q S SE +
Sbjct: 1410 RKATFWKEQKPGG-------DLESLCPWESTDFRG---PSAVSIQAPGS---SECSGSLG 1456
Query: 1042 FSLKEKSHHKPKAAEVC--QQSNQKRIDKAEVCLWESQGQSILEDEKLLISKTPVLPERA 1099
+ AEVC + + I KAE+C WE + ++ L + L E+
Sbjct: 1457 SGI----------AEVCLWEAGDAPAIQKAEICPWELDDNVMGQEMLSLGTGRESLQEKE 1506
Query: 1100 KEENGGQ--------PRAANVCAGQSEELPPK-----AVASKTENENLNQIGHQEKKTSS 1146
K G +A + Q E + P+ +S + + ++ G Q
Sbjct: 1507 KASRKGSFGEMGEQTVKAVQKLSQQQESVCPRESTVPGHSSPCLDNSSSKAGSQFLCNGG 1566
Query: 1147 SE-ENVRGSYNSSNNFQQPLTSRAEVCPWEFETPAQPNAGRSVALPASSALSANKIAGPR 1205
S V + Q+ ++ E+CPWE + S +P +K P
Sbjct: 1567 SRATQVCPQEDLRPEAQEATPAKTEICPWEVNERTR-EEWTSAQVPRGGESQKDKEKMPG 1625
Query: 1206 KEEIWD 1211
K EI D
Sbjct: 1626 KSEIED 1631
Score = 41.2 bits (95), Expect = 0.006
Identities = 69/320 (21%), Positives = 116/320 (36%), Gaps = 62/320 (19%)
Query: 900 QKSLSVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQ 959
QK+ S A +EK L G+ + G E+ +K L + +ET N D E+ AP+
Sbjct: 1833 QKAGSESAEQREKALE-KGRLTSLG-EDVSKGMAKLCQQQETICIWENKDLRESPAQAPK 1890
Query: 960 --------NSNPAE----------EPRKPQKSGIMKQQRVNPTTANSDLNPGTTQ--MKD 999
+S AE + R+ K+G + +D TT+ K
Sbjct: 1891 ISDLPSSMSSEVAEGHSLEATEKGDLRQDPKTGSFPEHITQEKAPAADTEEFTTEDGEKT 1950
Query: 1000 NFDIGEVCPWEVYDLTPGPVPSESKVQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQ 1059
+ ++ VCPWE T P S S + + + P S + +AA+VC
Sbjct: 1951 SHELQSVCPWE----TTAPADSVSHLDR-------QRPDQPKASSQRLVSTGGRAADVCP 1999
Query: 1060 QS-------NQKRIDKAEVCLWESQGQSILEDEKLLISKTPVLPERAKEENGGQPRAANV 1112
KAE C WE + ++ K E+ + +P+ V
Sbjct: 2000 WDVPDAGVYKSDSSAKAETCPWEVTERIPVKGVSRQDGKGDSQEEKGRAPEKSEPKGVPV 2059
Query: 1113 CAGQSEELPPKAVASKTEN----ENLNQIGHQEKKTSSSEENVRGSYNSSNNFQQ----- 1163
++ P A + E E+ + G + + + RGS ++ + +
Sbjct: 2060 -----QKKPEMADFRQQEAVCPWESQDGKGLSPQPAPDASDRSRGSSEAAGSVETRVAEV 2114
Query: 1164 --------PLTSRAEVCPWE 1175
P +AE+CPWE
Sbjct: 2115 CLWEVVEAPSAKKAEICPWE 2134
Score = 39.7 bits (91), Expect = 0.018
Identities = 48/232 (20%), Positives = 82/232 (35%), Gaps = 45/232 (19%)
Query: 992 PGTTQMKDNFDIGEVCPWEVYDLTPGPVPSESKVQKHVSIVASEMEKNPTFSLKEKSHHK 1051
P Q + ++CPWEV + T G + + +EK SL E
Sbjct: 1803 PWEAQEAATSEKAKICPWEVSEGTTGKGLDQKAGSESAEQREKALEKGRLTSLGEDV--S 1860
Query: 1052 PKAAEVCQQSNQKRIDKAEVCLWESQGQSILEDEKLLISKTPVLPERAKEENGGQPRAAN 1111
A++CQQ +C+WE++ +E P+ ++
Sbjct: 1861 KGMAKLCQQQET-------ICIWENKD--------------------LRESPAQAPKISD 1893
Query: 1112 VCAGQSEELPPKAVASKTENENLNQIGHQEKKTSSSEENVRGSYNSSNNFQQPLTSRAE- 1170
+ + S E+ TE +L Q + KT S E++ + + ++ T E
Sbjct: 1894 LPSSMSSEVAEGHSLEATEKGDLRQ----DPKTGSFPEHITQEKAPAADTEEFTTEDGEK 1949
Query: 1171 -------VCPWEFETPAQPNAGRSVALPASSALSANKI--AGPRKEEI--WD 1211
VCPWE PA + P S+ ++ G R ++ WD
Sbjct: 1950 TSHELQSVCPWETTAPADSVSHLDRQRPDQPKASSQRLVSTGGRAADVCPWD 2001
Score = 38.1 bits (87), Expect = 0.051
Identities = 92/433 (21%), Positives = 153/433 (35%), Gaps = 61/433 (14%)
Query: 786 ALIRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHV--RDQTEESSSLPTESQEEET 843
+L K G+ G+ E+T+K +++K + V R+ T S P
Sbjct: 1501 SLQEKEKASRKGSFGEMGEQTVK----AVQKLSQQQESVCPRESTVPGHSSPCLDNSSSK 1556
Query: 844 TENSTLESLSGKKLTQKL-KEDSEAESTESVPL---VCKSASAHNLSSEKKTGH-PRTSM 898
+ L + G + TQ +ED E+ E+ P +C E + PR
Sbjct: 1557 AGSQFLCN-GGSRATQVCPQEDLRPEAQEATPAKTEICPWEVNERTREEWTSAQVPRGGE 1615
Query: 899 LQKSLSVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAP 958
QK KEK + GK++ V K + + K + S + + P P
Sbjct: 1616 SQKD-------KEK---MPGKSEIEDVTAWEKPEGQIQKQEAVGPWESVDPGSFSPQPRP 1665
Query: 959 QNSNPAEEPRKPQKSGIMKQQRVNPTTANSDLNPGTTQMKDNFDIGEVCPWEVYDLTPGP 1018
Q++ + + S K + P +L G E+CPWEV G
Sbjct: 1666 QDTERPQTLLQMSGSVGSKAADICPLDVEENLTAGKA---------EICPWEV-----GA 1711
Query: 1019 VPSESKVQKHVSIVASEMEKNPTFSLKEKSHHKPK-AAEVCQQSNQKRIDKAEV-CLWES 1076
E + ++ A + K+P + K + P+ A + QK + EV C W S
Sbjct: 1712 GAGEER-----ALGAEAIRKSPNDTGKVSADLGPRERAVTAPEKPQKPTPEWEVACPWGS 1766
Query: 1077 QGQSILEDEK-LLISKTPVLPERAKEENGGQP------RAANVCAGQSEELPPKAVASKT 1129
G L + P + + G +P A + ++ P V+ T
Sbjct: 1767 VGPGACSQHPGTLDADGPKAGFQELDHMGCRPGEVCPWEAQEAATSEKAKICPWEVSEGT 1826
Query: 1130 ENENLNQIGHQEKKTSSSEENVRGSYNS-----SNNFQQPLTSRAEVCPWE----FETPA 1180
+ L+Q E + +G S S + + +C WE E+PA
Sbjct: 1827 TGKGLDQKAGSESAEQREKALEKGRLTSLGEDVSKGMAKLCQQQETICIWENKDLRESPA 1886
Query: 1181 QPNAGRSVALPAS 1193
Q A + LP+S
Sbjct: 1887 Q--APKISDLPSS 1897
>gi|239751284 PREDICTED: hypothetical protein XP_002347797 [Homo
sapiens]
Length = 1674
Score = 160 bits (404), Expect = 9e-39
Identities = 95/228 (41%), Positives = 131/228 (57%), Gaps = 19/228 (8%)
Query: 77 EVPMDVA----SYLYTGDSHQLKRANCSGRYELAGLPGKWPALASAHPSLHRALDTLTHA 132
+VP++ A +YLY+GD+ QL + NCS RYE G G P L PSL A TL A
Sbjct: 50 QVPLEGAEAALAYLYSGDAQQLSQVNCSERYEARGA-GAMPGLP---PSLQGAAGTLAQA 105
Query: 133 TNFLNVMLQSNKSREQNLQDDLDWYQALVWSLLEGEPSISRAAITFSTDSLSAPAPQVFL 192
NFLN++LQ+N RE ++++D++WYQALV S+ EG+P + RA +TF+ A Q+ L
Sbjct: 106 ANFLNMLLQANDIRESSVEEDVEWYQALVRSVAEGDPRVYRALLTFNPPP-GASHLQLAL 164
Query: 193 QATREESRILLQDLSSSAPHLANATLETEWFHGLRRKWRPHLHRRGPNQGPRGLGH-SWR 251
QATR +LQDLS + N + + P L +R LG W
Sbjct: 165 QATRTGEETILQDLSGNWVQEENPPGDLD---------TPALKKRVLTNDLGSLGSPKWP 215
Query: 252 RKDGLGGDKSHFKWSPPYLECENGSYKPGWLVTLSSAIYGLQPNLVPE 299
+ DG GD + SPP+LEC+ G +PGWL+TLS+ YGL+P+L PE
Sbjct: 216 QADGYVGDTQQVRLSPPFLECQEGRLRPGWLITLSATFYGLKPDLSPE 263
Score = 51.2 bits (121), Expect = 6e-06
Identities = 106/476 (22%), Positives = 165/476 (34%), Gaps = 125/476 (26%)
Query: 741 QKKRCSKKG----LGRSIMRRITEIPETVSRQCSKEDKEGADHGTAKGTALIRKNPPESS 796
Q+++ +KG LG + + + ++ + C E+K+ + + S
Sbjct: 1149 QREKALEKGRLTSLGEDVSKGMAKLCQQQETICIWENKDLRESPAQAPKISDLPSSMSSE 1208
Query: 797 GNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQEEETTENSTLESLSGKK 856
G S E T K + K+ S +H+ T+E + P EE TTE+ G+K
Sbjct: 1209 VAEGHSLEATEKGDLRQDPKTGSFPEHI---TQEKA--PAADTEEFTTED-------GEK 1256
Query: 857 LTQKLKEDSEAESTESVPLVCKSASAHNLS--SEKKTGHPRTSMLQKSLSVIASAKEKTL 914
+ +L+ E+T A A ++S ++ P+ S S ++++
Sbjct: 1257 TSHELQSVCPWETT---------APADSVSHLDRQRPDQPKAS----SQRLVSTGGRAAD 1303
Query: 915 GLAGKTQTAGVEERTKSQKP----------LPKDKETNRNHSNSDNTETKDPAPQNSNPA 964
AGV + S K +P K +R D+ E K AP+ S P
Sbjct: 1304 VCPWDVPDAGVYKSDSSAKAETCPWEVTERIPV-KGVSRQDGKGDSQEEKGRAPEKSEPK 1362
Query: 965 EEP--RKPQKSGIMKQQRVNPTTANSDLNPGTTQMKDNFDIGEVCPWEVYD---LTPGPV 1019
P +KP+ + +Q+ V CPWE D L+P P
Sbjct: 1363 GVPVQKKPEMADFRQQEAV-------------------------CPWESQDGKGLSPQPA 1397
Query: 1020 PSESKVQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVC--QQSNQKRIDKAEVCLWESQ 1077
P S + S A +E + AEVC + KAE+C WE+
Sbjct: 1398 PDASDRSRGSSEAAGSVET--------------RVAEVCLWEVVEAPSAKKAEICPWEAG 1443
Query: 1078 GQSILEDEKLLISKTPVLPERAKEENGGQPRAANVCAGQSEELPPKAVASKTENEN---- 1133
G + E E + + + G+ G +EE KA A E E
Sbjct: 1444 GGAAEEGE-----------QERESQGQGEMFLQKAGPGGTEEHFSKAAAKPREQEAVCPG 1492
Query: 1134 --------LNQIG--HQEKKTSSSEENVRGSYNSSNNFQQPLTSRAEVCPWEFETP 1179
L Q G E K S E GS AE+C WE P
Sbjct: 1493 EGTGSGGLLPQSGALDPELKVSPKEAGSMGS------------RMAELCQWEITDP 1536
Score = 50.4 bits (119), Expect = 1e-05
Identities = 104/527 (19%), Positives = 187/527 (35%), Gaps = 71/527 (13%)
Query: 665 PKFSHSSNNPRDDIATEAYEDELDMGRSGSYLNSSINSAWSEHSLDPEDIRDELKKLYAQ 724
P+ H S P A ++ R+G + +++ + H + D+ ++ K++ +
Sbjct: 322 PERGHHSPAPARARLWRALSVAVEKSRAGE---NEMDAEDAHHQREANDVDEDRPKIFPK 378
Query: 725 LEIYKRKKMITNNPHLQKKRCSKKGLGRSIMRRITEIPETVSRQCSKEDKEGADHGTAKG 784
K ++G RS+ I + + S KE E + G G
Sbjct: 379 SHSLKAPV--------------QQGSMRSLGLAIKALTRSRSTYREKESVEESPEGQNSG 424
Query: 785 TALIRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQEEETT 844
TA P S G+ K + + + S + Q +S + Q E +
Sbjct: 425 TAGESMGAPSRSPRLGRPKAVSKQAALIPSDDKESLQNQ---QNAHTSRMLQVCQREGSR 481
Query: 845 ENSTLESLSGKKLTQKLKE-DSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQKSL 903
E G+++TQ L E +E + ++ + + N+ K+T + + L
Sbjct: 482 EQED----RGRRMTQGLGERKAERAGKTGLAMLRQVSRDKNIKQSKETPVGWQELPKAGL 537
Query: 904 SVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQNSNP 963
+ SA + + E T+S+ P + N + ET + AP++
Sbjct: 538 QSLGSADHRVAEVCPW-------EVTESETRQPD----SGNKAEICPWETSEGAPESRAL 586
Query: 964 AEEPRKPQKSGIMKQQRVNPTTANSDLNPGTTQMKDNF--DIGEVCPWEVYD---LTPGP 1018
++P QK K+ + D+ P + + + VCPWE D L+PG
Sbjct: 587 RQDPGDSQK----KRGEARGKSEPIDVVPMMRKKPERLVREQEAVCPWESADRGGLSPGS 642
Query: 1019 VPSE-----SKVQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQQSNQKRIDKAEVCL 1073
P + K + S+ A ++EK P + H P I KAE C
Sbjct: 643 APQDPGRIRDKSEAGDSVEARKVEK-PGWEAAGPEAHTPD------------ITKAEPCP 689
Query: 1074 WESQGQSILEDEKLLISKTPVLPERAKEENGGQPRAANVCAGQSEELPPKAVASKTENEN 1133
WE+ ED K LP+ ++ G E L P T+
Sbjct: 690 WEASEGG--EDGKPAQEAVKDLPQEKQKTRKATFWKEQKPGGDLESLCPW---ESTDFRG 744
Query: 1134 LNQIGHQEKKTSSSEENVRGSYNSSNNFQQ---PLTSRAEVCPWEFE 1177
+ + Q +S ++ ++ P +AE+CPWE +
Sbjct: 745 PSAVSIQAPGSSECSGSLGSGIAEVCLWEAGDAPAIQKAEICPWELD 791
Score = 46.2 bits (108), Expect = 2e-04
Identities = 101/486 (20%), Positives = 174/486 (35%), Gaps = 61/486 (12%)
Query: 748 KGLGRSIMRRITEIPETVSRQCSKEDKEGADHGTAKGTALIRKNPPESSGNTGKSKEETL 807
+GLG R + + RQ S++ T G + K +S G+
Sbjct: 492 QGLGERKAERAGKTGLAMLRQVSRDKNIKQSKETPVGWQELPKAGLQSLGSAD------- 544
Query: 808 KNRVFSLKKSHSTYDHVR--DQTEESSSLPTESQEEETTENSTLESLSGKKLTQKLKEDS 865
+RV + T R D ++ P E+ E E+ L G ++ +
Sbjct: 545 -HRVAEVCPWEVTESETRQPDSGNKAEICPWETSEG-APESRALRQDPGDSQKKRGEARG 602
Query: 866 EAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQKSLSVIASAKEKTLGLAGKTQTAGV 925
++E + VP++ K L E++ P S + LS SA + + K++
Sbjct: 603 KSEPIDVVPMMRKKPE--RLVREQEAVCPWESADRGGLSP-GSAPQDPGRIRDKSEAGDS 659
Query: 926 EERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQNSNPAEEPRKPQKSGI----MKQQRV 981
E K +KP E +++ + +P P ++ E KP + + ++Q+
Sbjct: 660 VEARKVEKP---GWEAAGPEAHTPDITKAEPCPWEASEGGEDGKPAQEAVKDLPQEKQKT 716
Query: 982 NPTTANSDLNPGTTQMKDNFDIGEVCPWEVYDLTPGPVPSESKVQKHVSIVASEMEKNPT 1041
T + PG D+ +CPWE D PS +Q S SE +
Sbjct: 717 RKATFWKEQKPGG-------DLESLCPWESTDFRG---PSAVSIQAPGS---SECSGSLG 763
Query: 1042 FSLKEKSHHKPKAAEVC--QQSNQKRIDKAEVCLWESQGQSILEDEKLLISKTPVLPERA 1099
+ AEVC + + I KAE+C WE + ++ L + L E+
Sbjct: 764 SGI----------AEVCLWEAGDAPAIQKAEICPWELDDNVMGQEMLSLGTGRESLQEKE 813
Query: 1100 KEENGGQ--------PRAANVCAGQSEELPPK-----AVASKTENENLNQIGHQEKKTSS 1146
K G +A + Q E + P+ +S + + ++ G Q
Sbjct: 814 KASRKGSFGEMGEQTVKAVQKLSQQQESVCPRESTVPGHSSPCLDNSSSKAGSQFLCNGG 873
Query: 1147 SE-ENVRGSYNSSNNFQQPLTSRAEVCPWEFETPAQPNAGRSVALPASSALSANKIAGPR 1205
S V + Q+ ++ E+CPWE + S +P +K P
Sbjct: 874 SRATQVCPQEDLRPEAQEATPAKTEICPWEVNERTR-EEWTSAQVPRGGESQKDKEKMPG 932
Query: 1206 KEEIWD 1211
K EI D
Sbjct: 933 KSEIED 938
Score = 41.2 bits (95), Expect = 0.006
Identities = 69/320 (21%), Positives = 116/320 (36%), Gaps = 62/320 (19%)
Query: 900 QKSLSVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQ 959
QK+ S A +EK L G+ + G E+ +K L + +ET N D E+ AP+
Sbjct: 1140 QKAGSESAEQREKALE-KGRLTSLG-EDVSKGMAKLCQQQETICIWENKDLRESPAQAPK 1197
Query: 960 --------NSNPAE----------EPRKPQKSGIMKQQRVNPTTANSDLNPGTTQ--MKD 999
+S AE + R+ K+G + +D TT+ K
Sbjct: 1198 ISDLPSSMSSEVAEGHSLEATEKGDLRQDPKTGSFPEHITQEKAPAADTEEFTTEDGEKT 1257
Query: 1000 NFDIGEVCPWEVYDLTPGPVPSESKVQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQ 1059
+ ++ VCPWE T P S S + + + P S + +AA+VC
Sbjct: 1258 SHELQSVCPWE----TTAPADSVSHLDR-------QRPDQPKASSQRLVSTGGRAADVCP 1306
Query: 1060 QS-------NQKRIDKAEVCLWESQGQSILEDEKLLISKTPVLPERAKEENGGQPRAANV 1112
KAE C WE + ++ K E+ + +P+ V
Sbjct: 1307 WDVPDAGVYKSDSSAKAETCPWEVTERIPVKGVSRQDGKGDSQEEKGRAPEKSEPKGVPV 1366
Query: 1113 CAGQSEELPPKAVASKTEN----ENLNQIGHQEKKTSSSEENVRGSYNSSNNFQQ----- 1163
++ P A + E E+ + G + + + RGS ++ + +
Sbjct: 1367 -----QKKPEMADFRQQEAVCPWESQDGKGLSPQPAPDASDRSRGSSEAAGSVETRVAEV 1421
Query: 1164 --------PLTSRAEVCPWE 1175
P +AE+CPWE
Sbjct: 1422 CLWEVVEAPSAKKAEICPWE 1441
Score = 39.7 bits (91), Expect = 0.018
Identities = 48/232 (20%), Positives = 82/232 (35%), Gaps = 45/232 (19%)
Query: 992 PGTTQMKDNFDIGEVCPWEVYDLTPGPVPSESKVQKHVSIVASEMEKNPTFSLKEKSHHK 1051
P Q + ++CPWEV + T G + + +EK SL E
Sbjct: 1110 PWEAQEAATSEKAKICPWEVSEGTTGKGLDQKAGSESAEQREKALEKGRLTSLGEDV--S 1167
Query: 1052 PKAAEVCQQSNQKRIDKAEVCLWESQGQSILEDEKLLISKTPVLPERAKEENGGQPRAAN 1111
A++CQQ +C+WE++ +E P+ ++
Sbjct: 1168 KGMAKLCQQQET-------ICIWENKD--------------------LRESPAQAPKISD 1200
Query: 1112 VCAGQSEELPPKAVASKTENENLNQIGHQEKKTSSSEENVRGSYNSSNNFQQPLTSRAE- 1170
+ + S E+ TE +L Q + KT S E++ + + ++ T E
Sbjct: 1201 LPSSMSSEVAEGHSLEATEKGDLRQ----DPKTGSFPEHITQEKAPAADTEEFTTEDGEK 1256
Query: 1171 -------VCPWEFETPAQPNAGRSVALPASSALSANKI--AGPRKEEI--WD 1211
VCPWE PA + P S+ ++ G R ++ WD
Sbjct: 1257 TSHELQSVCPWETTAPADSVSHLDRQRPDQPKASSQRLVSTGGRAADVCPWD 1308
Score = 38.1 bits (87), Expect = 0.051
Identities = 92/433 (21%), Positives = 153/433 (35%), Gaps = 61/433 (14%)
Query: 786 ALIRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHV--RDQTEESSSLPTESQEEET 843
+L K G+ G+ E+T+K +++K + V R+ T S P
Sbjct: 808 SLQEKEKASRKGSFGEMGEQTVK----AVQKLSQQQESVCPRESTVPGHSSPCLDNSSSK 863
Query: 844 TENSTLESLSGKKLTQKL-KEDSEAESTESVPL---VCKSASAHNLSSEKKTGH-PRTSM 898
+ L + G + TQ +ED E+ E+ P +C E + PR
Sbjct: 864 AGSQFLCN-GGSRATQVCPQEDLRPEAQEATPAKTEICPWEVNERTREEWTSAQVPRGGE 922
Query: 899 LQKSLSVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAP 958
QK KEK + GK++ V K + + K + S + + P P
Sbjct: 923 SQKD-------KEK---MPGKSEIEDVTAWEKPEGQIQKQEAVGPWESVDPGSFSPQPRP 972
Query: 959 QNSNPAEEPRKPQKSGIMKQQRVNPTTANSDLNPGTTQMKDNFDIGEVCPWEVYDLTPGP 1018
Q++ + + S K + P +L G E+CPWEV G
Sbjct: 973 QDTERPQTLLQMSGSVGSKAADICPLDVEENLTAGKA---------EICPWEV-----GA 1018
Query: 1019 VPSESKVQKHVSIVASEMEKNPTFSLKEKSHHKPK-AAEVCQQSNQKRIDKAEV-CLWES 1076
E + ++ A + K+P + K + P+ A + QK + EV C W S
Sbjct: 1019 GAGEER-----ALGAEAIRKSPNDTGKVSADLGPRERAVTAPEKPQKPTPEWEVACPWGS 1073
Query: 1077 QGQSILEDEK-LLISKTPVLPERAKEENGGQP------RAANVCAGQSEELPPKAVASKT 1129
G L + P + + G +P A + ++ P V+ T
Sbjct: 1074 VGPGACSQHPGTLDADGPKAGFQELDHMGCRPGEVCPWEAQEAATSEKAKICPWEVSEGT 1133
Query: 1130 ENENLNQIGHQEKKTSSSEENVRGSYNS-----SNNFQQPLTSRAEVCPWE----FETPA 1180
+ L+Q E + +G S S + + +C WE E+PA
Sbjct: 1134 TGKGLDQKAGSESAEQREKALEKGRLTSLGEDVSKGMAKLCQQQETICIWENKDLRESPA 1193
Query: 1181 QPNAGRSVALPAS 1193
Q A + LP+S
Sbjct: 1194 Q--APKISDLPSS 1204
>gi|46358417 glutamate receptor, metabotropic 3 precursor [Homo
sapiens]
Length = 879
Score = 55.8 bits (133), Expect = 2e-07
Identities = 73/314 (23%), Positives = 129/314 (41%), Gaps = 40/314 (12%)
Query: 388 EAYVCLPCREGCPFCADDSPCFVQEDKYLR-----------LAIISFQALCMLLDFVSML 436
+ + C+ C G AD + C+ + Y+R +A + F CM++
Sbjct: 542 DEFTCMDCGSGQWPTADLTGCYDLPEDYIRWEDAWAIGPVTIACLGFMCTCMVVT----- 596
Query: 437 VVYHFRKAKSIRASGLILLETILFGSLLLYFPVVILYFEPSTFRCILLRWARLLGFATVY 496
V ++ASG L +LFG L Y +PS C L R FA Y
Sbjct: 597 VFIKHNNTPLVKASGRELCYILLFGVGLSYCMTFFFIAKPSPVICALRRLGLGSSFAICY 656
Query: 497 GTVTLKLHRVLKVF--LSRTAQRIPYMT-GGRVMRMLAVIL----LVVFWFLIGWTSSVC 549
+ K + + ++F + AQR +++ +V L +IL +V W ++ +
Sbjct: 657 SALLTKTNCIARIFDGVKNGAQRPKFISPSSQVFICLGLILVQIVMVSVWLILEAPGTRR 716
Query: 550 QNL-EKQISLIGQGKTSDHLIFNMCLIDRWDYMTAVAEFLFLLWGVYLCYAVRTVPSAFH 608
L EK+ ++I + D +M + +D + L +L VY + R P F+
Sbjct: 717 YTLAEKRETVILKCNVKDS---SMLISLTYDVI------LVILCTVY-AFKTRKCPENFN 766
Query: 609 EPRYMAVAVHNELIISAIFHTIRFVLAS--RLQSDWMLMLYFAHTHLTVTVTIGLLLIPK 666
E +++ ++ II F I +V +S R+Q+ M + L+ V +G L PK
Sbjct: 767 EAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCI----SVSLSGFVVLGCLFAPK 822
Query: 667 FSHSSNNPRDDIAT 680
P+ ++ T
Sbjct: 823 VHIILFQPQKNVVT 836
>gi|166999223 glutamate receptor, metabotropic 1 isoform beta
precursor [Homo sapiens]
Length = 906
Score = 55.8 bits (133), Expect = 2e-07
Identities = 74/352 (21%), Positives = 135/352 (38%), Gaps = 57/352 (16%)
Query: 357 GFYHPGVLPVNNFRRRGPDQHISGSTKDVSEE-----------------AYVCLPCREG- 398
G +H GVL +++++ + + SG + V E ++C C+E
Sbjct: 498 GTWHEGVLNIDDYKIQ---MNKSGVVRSVCSEPCLKGQIKVIRKGEVSCCWICTACKENE 554
Query: 399 -------CPFC-------ADDSPCFVQEDKYLR------LAIISFQALCMLLDFVSMLVV 438
C C AD + C +YL + I+F L +L+ L+
Sbjct: 555 YVQDEFTCKACDLGWWPNADLTGCEPIPVRYLEWSNIESIIAIAFSCLGILVTLFVTLIF 614
Query: 439 YHFRKAKSIRASGLILLETILFGSLLLYFPVVILYFEPSTFRCILLRWARLLGFATVYGT 498
+R +++S L IL G L Y L +P+T C L R L A Y
Sbjct: 615 VLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSA 674
Query: 499 VTLKLHRVLKVFLS---RTAQRIPYMTGGRVMRMLAVILLVVFWFLIGWTSSVCQNLEKQ 555
+ K +R+ ++ + R P ++A IL+ V L+ +E
Sbjct: 675 LVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLV----VTLIIMEPP 730
Query: 556 ISLIGQGKTSDHLIFNMCLIDRWDYMTAVA-EFLFLLWGVYLCYAVRTVPSAFHEPRYMA 614
+ ++ + ++ +C + + L ++ Y + R VP+ F+E +Y+A
Sbjct: 731 MPILSYPSIKE--VYLICNTSNLGVVAPLGYNGLLIMSCTYYAFKTRNVPANFNEAKYIA 788
Query: 615 VAVHNELIISAIFHTIRFVLASRLQSDWMLMLYFAHTHLTVTVTIGLLLIPK 666
++ II F I F S++ ++ L+VTV +G + PK
Sbjct: 789 FTMYTTCIIWLAFVPIYF------GSNYKIITTCFAVSLSVTVALGCMFTPK 834
>gi|166999098 glutamate receptor, metabotropic 1 isoform alpha
precursor [Homo sapiens]
Length = 1194
Score = 55.8 bits (133), Expect = 2e-07
Identities = 74/352 (21%), Positives = 135/352 (38%), Gaps = 57/352 (16%)
Query: 357 GFYHPGVLPVNNFRRRGPDQHISGSTKDVSEE-----------------AYVCLPCREG- 398
G +H GVL +++++ + + SG + V E ++C C+E
Sbjct: 498 GTWHEGVLNIDDYKIQ---MNKSGVVRSVCSEPCLKGQIKVIRKGEVSCCWICTACKENE 554
Query: 399 -------CPFC-------ADDSPCFVQEDKYLR------LAIISFQALCMLLDFVSMLVV 438
C C AD + C +YL + I+F L +L+ L+
Sbjct: 555 YVQDEFTCKACDLGWWPNADLTGCEPIPVRYLEWSNIESIIAIAFSCLGILVTLFVTLIF 614
Query: 439 YHFRKAKSIRASGLILLETILFGSLLLYFPVVILYFEPSTFRCILLRWARLLGFATVYGT 498
+R +++S L IL G L Y L +P+T C L R L A Y
Sbjct: 615 VLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSA 674
Query: 499 VTLKLHRVLKVFLS---RTAQRIPYMTGGRVMRMLAVILLVVFWFLIGWTSSVCQNLEKQ 555
+ K +R+ ++ + R P ++A IL+ V L+ +E
Sbjct: 675 LVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLV----VTLIIMEPP 730
Query: 556 ISLIGQGKTSDHLIFNMCLIDRWDYMTAVA-EFLFLLWGVYLCYAVRTVPSAFHEPRYMA 614
+ ++ + ++ +C + + L ++ Y + R VP+ F+E +Y+A
Sbjct: 731 MPILSYPSIKE--VYLICNTSNLGVVAPLGYNGLLIMSCTYYAFKTRNVPANFNEAKYIA 788
Query: 615 VAVHNELIISAIFHTIRFVLASRLQSDWMLMLYFAHTHLTVTVTIGLLLIPK 666
++ II F I F S++ ++ L+VTV +G + PK
Sbjct: 789 FTMYTTCIIWLAFVPIYF------GSNYKIITTCFAVSLSVTVALGCMFTPK 834
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 55.5 bits (132), Expect = 3e-07
Identities = 70/283 (24%), Positives = 115/283 (40%), Gaps = 19/283 (6%)
Query: 783 KGTALIRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQEEE 842
K +L+R++ S + K++ K+R ++S S+ R + ++SS E E
Sbjct: 169 KPYSLVRESSSSRSPTPKQKKKKKKKDRG---RRSESSSP--RRERKKSSKKKKHRSESE 223
Query: 843 TTENSTLESLSGKKLTQKLKEDSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQKS 902
+ + K K K+ + ST P KS AH +S TS +S
Sbjct: 224 SKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAP---KSRRAHRSTSADSASSSDTS---RS 277
Query: 903 LSVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQNSN 962
S A+AK T LAG++ + R + P + T+ +S T TK P S+
Sbjct: 278 RSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQP----SS 333
Query: 963 PAEEPRKPQKSGIMKQQRVNPTTANSDLN-PGTTQMKDNFDIGEVCPWEVYDLTPGPV-- 1019
P E+ K +K + +P +++ P T + G P L+ PV
Sbjct: 334 PYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNP 393
Query: 1020 PSESKVQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQQSN 1062
PSE+ + S S EK P S E S P+ +V + ++
Sbjct: 394 PSEASPTRDRSPPKSP-EKLPQSSSSESSPPSPQPTKVSRHAS 435
Score = 34.3 bits (77), Expect = 0.74
Identities = 54/280 (19%), Positives = 100/280 (35%), Gaps = 43/280 (15%)
Query: 741 QKKRCSKKGLGRSIMRRITEIPETVSRQCSKEDKEGADHGTAKGTALIRKNPPESSGNTG 800
QKK+ KK GR R + P ++ SK+ K ++ + K RK+ + +
Sbjct: 187 QKKKKKKKDRGR---RSESSSPRRERKKSSKKKKHRSESESKK-----RKHRSPTPKSKR 238
Query: 801 KSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTE-SQEEETTENSTLESLSGKKLTQ 859
KSK++ K + S H + +SS T S+ + +L+G+ +
Sbjct: 239 KSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSP 298
Query: 860 KLKEDSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQKSLSVIASAKEKTLGLAGK 919
E ++ S P +S ++ P T+ Q S K+K A +
Sbjct: 299 ASGRRGEGDAPFSEP---------GTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATR 349
Query: 920 TQTAGVEERTKSQKPLPKDKETNRNHSN-----------------SDNTETKDPAP---- 958
+ T + P P R+ + S+ + T+D +P
Sbjct: 350 PSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSP 409
Query: 959 ----QNSNPAEEPRKPQKSGIMKQQRVNPTTANSDLNPGT 994
Q+S+ P PQ + + + +P + PG+
Sbjct: 410 EKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGS 449
Score = 34.3 bits (77), Expect = 0.74
Identities = 61/311 (19%), Positives = 98/311 (31%), Gaps = 16/311 (5%)
Query: 663 LIPKFSHSSNNPRDDIATEAYEDELDMGRSGSYLNSSINSAWSEHSLDPEDIRDELKKLY 722
L P+ S + D T A RSGS + + S D + K
Sbjct: 1510 LTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPD-SKAK 1568
Query: 723 AQLEIYKRKKMITNNPHLQKKRCSKKGLGRSIMRRITEIPETVSRQCSKEDKEGADHGTA 782
+ + +R + ++ K R S + + + P R S D A
Sbjct: 1569 TRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPA 1628
Query: 783 KGTALIRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQEEE 842
R SS G S E + S + S R S S P E + +
Sbjct: 1629 PRALPRRSRSGSSSKGRGPSPEGSS-----STESSPEHPPKSRTARRGSRSSP-EPKTKS 1682
Query: 843 TTENSTLESLSGKKLTQKLKEDSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQKS 902
T S S +LT+K + + S S P S H R+ +
Sbjct: 1683 RTPPRRRSSRSSPELTRKARLSRRSRSASSSP---------ETRSRTPPRHRRSPSVSSP 1733
Query: 903 LSVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQNSN 962
S + A +T R +S P P+ + +R+ S + T T ++ +
Sbjct: 1734 EPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGS 1793
Query: 963 PAEEPRKPQKS 973
R+ Q+S
Sbjct: 1794 SQSTSRRRQRS 1804
Score = 33.5 bits (75), Expect = 1.3
Identities = 49/270 (18%), Positives = 104/270 (38%), Gaps = 44/270 (16%)
Query: 919 KTQTAGVEERTKSQKPLPKDKETNRNHSN-SDNTETKDPAPQNSNPAEEPRK--PQKSGI 975
+++T R++S+ P + + +R + S + ++ PA + + + PR+ + +
Sbjct: 648 RSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSL 707
Query: 976 MKQQRVNPTTANSDLNPGTTQMKDNFDIGEVCPWEVYDLTPGPVPSESKVQKHVSIVASE 1035
+++ R + T G++ + N S + ++ S + E
Sbjct: 708 VRRGRSHSRTPQRRGRSGSSSERKN-------------------KSRTSQRRSRSNSSPE 748
Query: 1036 MEKNPTFSLKEKSHHKPKAAEVCQQSNQKRIDKAEVCLWESQGQSILEDEKLLISKTPVL 1095
M+K+ S + +S P++ + S ++ + + C + S+TP
Sbjct: 749 MKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQK-------------SQTP-- 793
Query: 1096 PERAKEENGGQPRAANVCA---GQSEELPPKAVASKTENENLNQIGHQEKKTSSSEENVR 1152
P R++ QP+A + +S PP SKT + + K S +
Sbjct: 794 PRRSRS-GSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQ 852
Query: 1153 GSYNSSNNFQQPLTSRAEVCPWEFETPAQP 1182
GS S +Q +T + C FE+ P
Sbjct: 853 GSITSPQANEQSVTPQRRSC---FESSPDP 879
Score = 33.1 bits (74), Expect = 1.7
Identities = 44/240 (18%), Positives = 90/240 (37%), Gaps = 20/240 (8%)
Query: 770 SKEDKEGADHGTAKGTALIRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRD--- 826
S +E ++ ++ + + P +G S E K+R+ + + V+D
Sbjct: 1550 SASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPR 1609
Query: 827 -----QTEESSSLPTESQEEETTENSTLESLSGKKLTQKLKEDSEAESTESVPLVCKSAS 881
Q+ SS ++ + S K + S ES+ P ++A
Sbjct: 1610 AAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTAR 1669
Query: 882 AHNLSS-EKKTGHPRTSMLQKSLSVIASAKEKTLGLAGKTQTAGVEERTKS--------- 931
+ SS E KT + S S ++ L ++ ++ E R+++
Sbjct: 1670 RGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPS 1729
Query: 932 -QKPLPKDKE-TNRNHSNSDNTETKDPAPQNSNPAEEPRKPQKSGIMKQQRVNPTTANSD 989
P P +K ++R ++ + TK + + +P+ +PR Q+S ++ TT D
Sbjct: 1730 VSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRD 1789
Score = 31.6 bits (70), Expect = 4.8
Identities = 55/290 (18%), Positives = 102/290 (35%), Gaps = 27/290 (9%)
Query: 908 SAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQNSNPAEE- 966
SA E+ G RT P + + T+ + + + P+ PA++
Sbjct: 2388 SAYERVSGRTSPPLLDRARSRTPPSAP-SQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQ 2446
Query: 967 PRKPQKSGIMKQQR-----VNPTTANSDLNPG-----TTQMKDNFDIGEVCPWEVYDLTP 1016
PR P S Q R P + L+ G T+ D+ + V V
Sbjct: 2447 PRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDV 2506
Query: 1017 GPVPSESKVQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQQSNQKRIDKAEVCLWES 1076
G P+ + Q+ ++ A + K S S ++ S+ + +S
Sbjct: 2507 GEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSS---DS 2563
Query: 1077 QGQSILEDEKLLI----SKTPVLPERAKEENGGQPRAANVCAGQSEELPPKAVASKTENE 1132
+G S+ ++ + S TP E +E +P A + ++ +S + +
Sbjct: 2564 EGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPA--------KRKRRSSSSSSSSS 2615
Query: 1133 NLNQIGHQEKKTSSSEENVRGSYNSSNNFQQPLTSRAEVCPWEFETPAQP 1182
+ + +SSS + S +SS++ S A+ P PA P
Sbjct: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASP 2665
>gi|219842343 glutamate receptor, metabotropic 5 isoform a precursor
[Homo sapiens]
Length = 1212
Score = 55.1 bits (131), Expect = 4e-07
Identities = 77/355 (21%), Positives = 141/355 (39%), Gaps = 37/355 (10%)
Query: 388 EAYVCLPCREGCPFCADDSPCFVQEDKYLR------LAIISFQALCMLLDFVSMLVVYHF 441
+ Y C C+ G D + C + +YLR +A + F L +L +V +
Sbjct: 545 DEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFIIY 604
Query: 442 RKAKSIRASGLILLETILFGSLLLYFPVVILYFEPSTFRCILLRWARLLGFATVYGTVTL 501
R +++S L IL G L Y L +P C L R L A Y +
Sbjct: 605 RDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVT 664
Query: 502 KLHRVLKVFLSRTAQRIPYMTGGRVMRMLAVILLVVFWFLIGWTSSVCQNLEKQISL--- 558
K +R+ ++ L+ + ++I + R ++ +V F++ +C L ++L
Sbjct: 665 KTNRIARI-LAGSKKKICT----KKPRFMSACAQLVIAFIL-----ICIQLGIIVALFIM 714
Query: 559 ----IGQGKTSDHLIFNMCLIDRWDYMTAVA-EFLFLLWGVYLCYAVRTVPSAFHEPRYM 613
I S ++ +C +T + L +L + + R VP+ F+E +Y+
Sbjct: 715 EPPDIMHDYPSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYI 774
Query: 614 AVAVHNELIISAIFHTIRFVLASRLQSDWMLMLYFAHTHLTVTVTIGLLLIPK----FSH 669
A ++ II F I F S++ ++ L+ TV +G + +PK +
Sbjct: 775 AFTMYTTCIIWLAFVPIYF------GSNYKIITMCFSVSLSATVALGCMFVPKVYIILAK 828
Query: 670 SSNNPRDDIATE-AYEDELDMGRSGSYL--NSSINSAWSEHSLDPEDIRDELKKL 721
N R T + G+S S +SS+ + W E +R + ++L
Sbjct: 829 PERNVRSAFTTSTVVRMHVGDGKSSSAASRSSSLVNLWKRRGSSGETLRYKDRRL 883
>gi|4504143 glutamate receptor, metabotropic 5 isoform b precursor
[Homo sapiens]
Length = 1180
Score = 54.3 bits (129), Expect = 7e-07
Identities = 87/402 (21%), Positives = 153/402 (38%), Gaps = 54/402 (13%)
Query: 388 EAYVCLPCREGCPFCADDSPCFVQEDKYLR------LAIISFQALCMLLDFVSMLVVYHF 441
+ Y C C+ G D + C + +YLR +A + F L +L +V +
Sbjct: 545 DEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFIIY 604
Query: 442 RKAKSIRASGLILLETILFGSLLLYFPVVILYFEPSTFRCILLRWARLLGFATVYGTVTL 501
R +++S L IL G L Y L +P C L R L A Y +
Sbjct: 605 RDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVT 664
Query: 502 KLHRVLKVFLSRTAQRIPYMTGGRVMRMLAVILLVVFWFLIGWTSSVCQNLEKQISL--- 558
K +R+ ++ L+ + ++I + R ++ +V F++ +C L ++L
Sbjct: 665 KTNRIARI-LAGSKKKICT----KKPRFMSACAQLVIAFIL-----ICIQLGIIVALFIM 714
Query: 559 ----IGQGKTSDHLIFNMCLIDRWDYMTAVA-EFLFLLWGVYLCYAVRTVPSAFHEPRYM 613
I S ++ +C +T + L +L + + R VP+ F+E +Y+
Sbjct: 715 EPPDIMHDYPSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYI 774
Query: 614 AVAVHNELIISAIFHTIRFVLASRLQSDWMLMLYFAHTHLTVTVTIGLLLIPK----FSH 669
A ++ II F I F S++ ++ L+ TV +G + +PK +
Sbjct: 775 AFTMYTTCIIWLAFVPIYF------GSNYKIITMCFSVSLSATVALGCMFVPKVYIILAK 828
Query: 670 SSNNPRDDIATE-AYEDELDMGRSGSYL--NSSINSAWSEHSLDPEDIRDELKK------ 720
N R T + G+S S +SS+ + W E + K
Sbjct: 829 PERNVRSAFTTSTVVRMHVGDGKSSSAASRSSSLVNLWKRRGSSGETLSSNGKSVTWAQN 888
Query: 721 --------LYAQLEIYKRKKMITNNPHLQK---KRCSKKGLG 751
L+ +L I+ KK N + K K +GLG
Sbjct: 889 EKSSRGQHLWQRLSIHINKKENPNQTAVIKPFPKSTESRGLG 930
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo
sapiens]
Length = 916
Score = 53.9 bits (128), Expect = 9e-07
Identities = 91/440 (20%), Positives = 160/440 (36%), Gaps = 47/440 (10%)
Query: 727 IYKRKKMITNNPHLQKKRCSKKGLGRSIMRRITEIPETVSRQCSKEDKEGADHGTAKGTA 786
+Y + IT + +QK + L + + + EI E + K + E A + A
Sbjct: 423 LYTHRPPITISSKIQKPKVEAPKL-KVQHKFVEEIIEETKVEDEKSEMEEALTAITEELA 481
Query: 787 LIRKNPPESSGNTGKSKEETLKNRVFSLKKS-HSTYDHVRDQT---EESSSLPTESQEEE 842
+ K + + + + E + V + K +T V+++ EE E +E+E
Sbjct: 482 VSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDE 541
Query: 843 TTENSTLESLSGKKLTQKLKEDSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQKS 902
++ E +K KE+ E E E+ ++ + E+K ++ +
Sbjct: 542 GAKSDQAEEGGSEKEGSSEKEEGEQEEGETE---AEAEGEEAEAKEEKKVEEKSEEVATK 598
Query: 903 LSVIASAK-EKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQNS 961
++A AK EK + VEE+ KS P +E ++ E K +P
Sbjct: 599 EELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPK 658
Query: 962 NPAEEPRKPQKSGIMKQQRVNPTTANSDLNPGTTQMKDNFDIGEVCPWEVYDLTPGPVPS 1021
+P EE K S +++ S + + K ++G+ E + P
Sbjct: 659 SPVEEKGKSPVSKSPVEEKAKSPVPKSPVE----EAKSKAEVGKGEQKEEEEKEVKEAPK 714
Query: 1022 ESKVQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQQSNQKRIDKAEVCLWESQGQSI 1081
E KV+K E+ P ++K P E AEV +
Sbjct: 715 EEKVEK--------KEEKPKDVPEKKKAESPVKEEAV----------AEVVTITKSVKVH 756
Query: 1082 LEDEKLLISKTPVLPERAKEENGGQPRAANVCAGQSEELPPKA--------VASKTENEN 1133
LE E K P+ E+ KE+ GG+ G EE K +A E E
Sbjct: 757 LEKETKEEGK-PLQQEKEKEKAGGE-------GGSEEEGSDKGAKGSRKEDIAVNGEVEG 808
Query: 1134 LNQIGHQEKKTSSSEENVRG 1153
++ + K+ S E +G
Sbjct: 809 KEEVEQETKEKGSGREEEKG 828
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo
sapiens]
Length = 540
Score = 53.9 bits (128), Expect = 9e-07
Identities = 91/440 (20%), Positives = 160/440 (36%), Gaps = 47/440 (10%)
Query: 727 IYKRKKMITNNPHLQKKRCSKKGLGRSIMRRITEIPETVSRQCSKEDKEGADHGTAKGTA 786
+Y + IT + +QK + L + + + EI E + K + E A + A
Sbjct: 47 LYTHRPPITISSKIQKPKVEAPKL-KVQHKFVEEIIEETKVEDEKSEMEEALTAITEELA 105
Query: 787 LIRKNPPESSGNTGKSKEETLKNRVFSLKKS-HSTYDHVRDQT---EESSSLPTESQEEE 842
+ K + + + + E + V + K +T V+++ EE E +E+E
Sbjct: 106 VSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDE 165
Query: 843 TTENSTLESLSGKKLTQKLKEDSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQKS 902
++ E +K KE+ E E E+ ++ + E+K ++ +
Sbjct: 166 GAKSDQAEEGGSEKEGSSEKEEGEQEEGETE---AEAEGEEAEAKEEKKVEEKSEEVATK 222
Query: 903 LSVIASAK-EKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQNS 961
++A AK EK + VEE+ KS P +E ++ E K +P
Sbjct: 223 EELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPK 282
Query: 962 NPAEEPRKPQKSGIMKQQRVNPTTANSDLNPGTTQMKDNFDIGEVCPWEVYDLTPGPVPS 1021
+P EE K S +++ S + + K ++G+ E + P
Sbjct: 283 SPVEEKGKSPVSKSPVEEKAKSPVPKSPVE----EAKSKAEVGKGEQKEEEEKEVKEAPK 338
Query: 1022 ESKVQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQQSNQKRIDKAEVCLWESQGQSI 1081
E KV+K E+ P ++K P E AEV +
Sbjct: 339 EEKVEK--------KEEKPKDVPEKKKAESPVKEEAV----------AEVVTITKSVKVH 380
Query: 1082 LEDEKLLISKTPVLPERAKEENGGQPRAANVCAGQSEELPPKA--------VASKTENEN 1133
LE E K P+ E+ KE+ GG+ G EE K +A E E
Sbjct: 381 LEKETKEEGK-PLQQEKEKEKAGGE-------GGSEEEGSDKGAKGSRKEDIAVNGEVEG 432
Query: 1134 LNQIGHQEKKTSSSEENVRG 1153
++ + K+ S E +G
Sbjct: 433 KEEVEQETKEKGSGREEEKG 452
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 53.5 bits (127), Expect = 1e-06
Identities = 108/515 (20%), Positives = 199/515 (38%), Gaps = 50/515 (9%)
Query: 717 ELKKLYAQLEIYKRKKMITNNPHLQKKRCSKKGLGRSIMRRITEIPETVSRQCSKEDKEG 776
ELK ++A+ E K + ++ + H+ + ++ L R RR T P + EG
Sbjct: 617 ELKHVHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRR-TSTPVIM---------EG 666
Query: 777 ADHGTAKGTALIRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPT 836
T + E + ++ TLKN LKK S H++ ++
Sbjct: 667 VQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKH-LKKDDSETPHLKSLLKKEVKSSK 725
Query: 837 ESQEEETTENSTLESLSGK---KLTQKLKEDSEAESTES----VPLVCKSASAHNLSSEK 889
E E E T + S+ K K +++E S+E + K + LSS+
Sbjct: 726 EKPEREKTPSEDKLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLSSDD 785
Query: 890 KTGHPRTSMLQKSLSVIASAKEKTLGLAGKTQTAGVEERTKSQKPL--PKDKETNRNHSN 947
KT ++ LSV+ + KT +E K ++ L K K +++ +
Sbjct: 786 KTERKSKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSAEKTKAEHKSRRS 845
Query: 948 SDNTETKDPAPQNSNPAEEPRKPQKSGIMKQQRVNPTTANSDLNPGTTQMKDNFDIGEVC 1007
SD+ KD + R+ + K ++ T +S+L P K+ +
Sbjct: 846 SDSKIQKDSLGSKQHGITLQRRSESYSEDKCD-MDSTNMDSNLKPEEVVHKEKRRTKSLL 904
Query: 1008 PWEVYDLTPGPVPSESKVQ-KHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQQSNQKRI 1066
++ + S+SK Q K V +V +E+++ T K K E S ++R
Sbjct: 905 EEKLV------LKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEE-NDSEKQRK 957
Query: 1067 DKAEVCLWESQG-QSILE----------DEKLLISKTPVLPERAKEENGG-----QPRAA 1110
K E +E G + +LE + +K P+ E+ K + + + +
Sbjct: 958 SKVEDKPFEETGVEPVLETASSSAHSTQKDSSHRAKLPLAKEKYKSDKDSTSTRLERKLS 1017
Query: 1111 NVCAGQSEELPPKAVASKTENENLNQIGHQEKKTSSSEENVRG--SYNSSNNFQQPLTSR 1168
+ +S + K + K EN++ ++ G K+ SS E RG S ++ +R
Sbjct: 1018 DGHKSRSLKHSSKDIKKKDENKSDDKDG---KEVDSSHEKARGNSSLMEKKLSRRLCENR 1074
Query: 1169 AEVCPWEFETPAQPNAGRSVALPASSALSANKIAG 1203
E + A +++ P+ S+L K +G
Sbjct: 1075 RGSLSQEMAKGEEKLAANTLSTPSGSSLQRPKKSG 1109
Score = 39.7 bits (91), Expect = 0.018
Identities = 84/386 (21%), Positives = 151/386 (39%), Gaps = 58/386 (15%)
Query: 790 KNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRD------QTEESSSLPTESQEEET 843
K P E + N K+ E T ++ FSL S D + D T + SS +++EE
Sbjct: 373 KLPSEKNSNKAKTVEGTKED--FSL--IDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVV 428
Query: 844 TENSTLE----SLSGKKLTQKLKEDSEAESTESVPLVCKSASAHN--LSSEKKTGHPRTS 897
T +S E S +K Q + ++S+E + A H L S+ +
Sbjct: 429 TSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDEL 488
Query: 898 MLQKSLSVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPA 957
+++ IA KE+ L L + +EE+ K + K +T +S + E
Sbjct: 489 TVEQRRQSIAKEKEERL-LRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLE----- 542
Query: 958 PQNSNPAEEPRKPQKSGIMKQQRVNPTTANSDLNPGTTQMKDNFDIGEVCPWEVYDLTPG 1017
++S + EP+ + ++K+++V + + KD+ ++ E
Sbjct: 543 -ESSTKSLEPKAARIKEVLKERKV----LEKKVALSKKRKKDSRNVEE------------ 585
Query: 1018 PVPSESKVQ-----KHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQQSNQKRIDKAEVC 1072
S+ K Q K + EK S KE H K+ +R+ ++
Sbjct: 586 --NSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHVHAKSEP---SKPARRLSESLHV 640
Query: 1073 LWESQGQSILEDEKLLISKTPVLPERAKEENG-----GQPRAANVCA----GQSEELPPK 1123
+ E++ +S LE E + TPV+ E +EE Q + +C Q L +
Sbjct: 641 VDENKNESKLEREHKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQKSTLKNE 700
Query: 1124 AVASKTENENLNQIGHQEKKTSSSEE 1149
K ++E + +K+ SS+E
Sbjct: 701 KHLKKDDSETPHLKSLLKKEVKSSKE 726
>gi|66529100 glutamate receptor, metabotropic 2 isoform a precursor
[Homo sapiens]
Length = 872
Score = 50.4 bits (119), Expect = 1e-05
Identities = 75/317 (23%), Positives = 127/317 (40%), Gaps = 46/317 (14%)
Query: 388 EAYVCLPCREGCPFCADDSPCFVQEDKYLR---------LAIISFQALCMLLDFVSMLVV 438
+ + C C G A + CF +Y+R + I AL L FV + V
Sbjct: 533 DEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLGALATL--FVLGVFV 590
Query: 439 YHFRKAKSIRASGLILLETILFGSLLLYFPVVILYFEPSTFRCILLRWARLLGFATVYGT 498
H ++ASG L +L G L Y I +PST C L R F+ Y
Sbjct: 591 RH-NATPVVKASGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSA 649
Query: 499 VTLKLHRVLKVF--LSRTAQRIPYMT-GGRVMRMLAVI----LLVVFWFLI---GWTSSV 548
+ K +R+ ++F AQR +++ +V LA+I L+VV W ++ G
Sbjct: 650 LLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQLLIVVAWLVVEAPGTGKET 709
Query: 549 CQNLEKQISLIGQGKTSD---HLIFNMCLIDRWDYMTAVAEFLFLLWGVYLCYAVRTVPS 605
+ ++L + + L +N+ LI L +Y + R P
Sbjct: 710 APERREVVTLRCNHRDASMLGSLAYNVLLI--------------ALCTLY-AFKTRKCPE 754
Query: 606 AFHEPRYMAVAVHNELIISAIFHTIRFVLAS--RLQSDWMLMLYFAHTHLTVTVTIGLLL 663
F+E +++ ++ II F I +V +S R+Q+ M + L+ +V +G L
Sbjct: 755 NFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCV----SVSLSGSVVLGCLF 810
Query: 664 IPKFSHSSNNPRDDIAT 680
PK P+ ++ +
Sbjct: 811 APKLHIILFQPQKNVVS 827
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 50.4 bits (119), Expect = 1e-05
Identities = 97/447 (21%), Positives = 171/447 (38%), Gaps = 61/447 (13%)
Query: 743 KRCSKKGLGRSIMRRITEIPETVSRQCSKEDKEGADHGTAKGTALIRKNPPESSGNTGKS 802
K+C +GRS + +IP ++ K+ K I+K K
Sbjct: 1664 KKCEALAVGRSSEKEGKDIPPDETQSTQKQHKPSLG---------IKKPVRRKLKEKQKQ 1714
Query: 803 KEETLKNRV--FSLKKSHSTYDHVRDQTEESSSLPTESQEEETTENSTLESLSGK-KLTQ 859
KEE L+ LKK S D LPT E + + S+ K K Q
Sbjct: 1715 KEEGLQASAEKAELKKGSSEESLGEDPGLAPEPLPTVKATSPLIEETPIGSIKDKVKALQ 1774
Query: 860 KLKEDSEAESTESVPLVCKS--------------ASAHNLSSEKKTGHPRTSMLQKSLSV 905
K ED E + +P+ K A++ +L SE+ + ++ ++
Sbjct: 1775 KRVED-EQKGRSKLPIRVKGKEDVPKKTTHRPHPAASPSLKSERHAPGSPSPKTERHSTL 1833
Query: 906 IASAKEK---TLGLAGKTQ---TAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQ 959
+SAK + + + KT+ +T+ P +T ++ S +T+T+ +P
Sbjct: 1834 SSSAKTERHPPVSPSSKTEKHSPVSPSAKTERHSPASSSSKTEKHSPVSPSTKTERHSPV 1893
Query: 960 NSNPAEEPRKPQKSG-IMKQQRVNP---TTANSDLNPGTTQMKDNFDIGEVCPWEVYDLT 1015
+S E SG K+ V+P T + ++PG T+ + V P D
Sbjct: 1894 SSTKTERHPPVSPSGKTDKRPPVSPSGRTEKHPPVSPGRTEKR-----LPVSPSGRTD-K 1947
Query: 1016 PGPVPSESKVQKHVSIVAS-EMEKNPTFSLKEKSHHKPKAAEVCQ-----QSNQKRIDKA 1069
PV + K +KH+ + S + EK P S K+ + V + QS Q K
Sbjct: 1948 HQPVSTAGKTEKHLPVSPSGKTEKQPPVSPTSKTERIEETMSVRELMKAFQSGQDP-SKH 2006
Query: 1070 EVCLWE---SQGQSILEDEKLLISKT--PVLPERAKEENGGQPRAANVCAGQSEELPPKA 1124
+ L+E ++ + E K+ + K P+L +R + + N + + LP
Sbjct: 2007 KTGLFEHKSAKQKQPQEKGKVRVEKEKGPILTQREAQ------KTENQTIKRGQRLPVTG 2060
Query: 1125 VASKTENENLNQIGHQEKKTSSSEENV 1151
A ++ IG +++ + +E V
Sbjct: 2061 TAESKRGVRVSSIGVKKEDAAGGKEKV 2087
Score = 38.5 bits (88), Expect = 0.039
Identities = 59/219 (26%), Positives = 93/219 (42%), Gaps = 23/219 (10%)
Query: 766 SRQCSKEDKEGADHGTA-KGTALIRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHV 824
S E G+ G+ +GT I ++ E + ++ FS KKS +
Sbjct: 2202 SESLKNEGVAGSPCGSLMEGTPQISSEESYKHEGLAETPETSPESLSFSPKKS----EEQ 2257
Query: 825 RDQTEESSSLPTESQEEETTENSTLESLSG--KKLTQKLKEDSEAESTESVPLVCKSASA 882
+T+ES+ T ++ E+ T + ++G ++ + EDSE STES K A+
Sbjct: 2258 TGETKESTKTETTTEIRSEKEHPTTKDITGGSEERGATVTEDSET-STESFQ---KEAT- 2312
Query: 883 HNLSSEKKTGHPRTSMLQKSLSVIASAKEKTLGLAGKTQTAGVEE--RT--KSQKPLPKD 938
L S K T R S SV A AKE GL T+ A +E RT S D
Sbjct: 2313 --LGSPKDTSPKRQDDCTGSCSV-ALAKETPTGL---TEEAACDEGQRTFGSSAHKTQTD 2366
Query: 939 KETNRNHSNSDNTETKDPAPQNSNPAEEPRKPQKSGIMK 977
E + + SD T+ P P+ S + + + G+++
Sbjct: 2367 SEVQESTATSDETKAL-PLPEASVKTDTGTESKPQGVIR 2404
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 49.7 bits (117), Expect = 2e-05
Identities = 91/469 (19%), Positives = 171/469 (36%), Gaps = 44/469 (9%)
Query: 754 IMRRITEIPETVSRQCSKEDKEGADHGTAKGTALIRKNPPESSGNTGKSKEETLKNRVFS 813
+ +TE E +++ +++EG + A+G K+PP S E+ K+ V
Sbjct: 466 VTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEA---ASPEKEAKSPV-- 520
Query: 814 LKKSHSTYDHVRDQTEESSSLPTESQEEETTE-NSTLESLSGKKLTQKLKEDSEAESTES 872
+E + P E++ E E S E S +K KE++++
Sbjct: 521 ---------------KEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAK 565
Query: 873 VPLVCKSASAHNLSSEKKTGHPRTSMLQKSLSVIASAKEKTLGLAGKTQTAGVEERTKSQ 932
P ++ S + S +K P + + K K+ A + K +
Sbjct: 566 SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEE 625
Query: 933 KPLPKDKETNRNHSNSDNTETKDPAPQNSNPAEEPRKPQKS-GIMKQQRVNPTTANSDL- 990
P + ++ + E K P S EE + P+K+ +K + +P A S +
Sbjct: 626 AKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVK 685
Query: 991 ------NPGTTQMKDNFDIGEVCPWEVYDLTPGPVPSESKVQKHVSIVASEMEKNPTFSL 1044
+ +K+ E V + P ++S V++ E K+P
Sbjct: 686 AEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAK--TPEKAKSPV-KE 742
Query: 1045 KEKSHHKPKAAEVCQQSNQKRIDKAEVCLWESQGQSILEDEKLLISKTPVLPERAKEENG 1104
+ KS K K+ E + + K + E++ + EK +K+PV E E
Sbjct: 743 EAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEK---AKSPVKEEVKSPEKA 799
Query: 1105 GQPRAANVCAGQSEELPPKAVASKT-ENENLNQIGHQEKKTSSSEENVRGSYNSSNNFQQ 1163
P + A + E + V S E E ++ +E + EE + + ++
Sbjct: 800 KSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKT----EE 855
Query: 1164 PLTSRAEVCPWEFETP---AQPNAGRSVALPASSALSANKIAGPRKEEI 1209
S+ E P + E P + +V P S + A K K+++
Sbjct: 856 KKDSKKEEAP-KKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKV 903
Score = 46.6 bits (109), Expect = 1e-04
Identities = 99/433 (22%), Positives = 158/433 (36%), Gaps = 52/433 (12%)
Query: 793 PESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQEEETTENSTLESL 852
P S + EE +K ++KS V +QTEE T+ EE T E E
Sbjct: 430 PSVSTHIKVKSEEKIK----VVEKSEKETVIVEEQTEE-----TQVTEEVTEE----EEK 476
Query: 853 SGKKLTQKLKEDSEAESTESVPLVCKSASAHNLSS-EKKTGHPRTSMLQKSLSVIASAKE 911
K+ K +E E E E KS A +S EK+ P + + KE
Sbjct: 477 EAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKE 536
Query: 912 KTLGLA-----GKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTE-TKDPAPQNSNPAE 965
+ A K ++ EE + +KE ++ + + E K PA + +
Sbjct: 537 EAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPA 596
Query: 966 EPRKPQKS-GIMKQQRVNPTTANSDLNPGTTQMKDNFDIGEVCPWEVYDLTPGPVPSESK 1024
E + P+K+ +K++ +P A S P + K ++ + + P E+K
Sbjct: 597 EAKSPEKAKSPVKEEAKSPAEAKS---PVKEEAKSPAEV------KSPEKAKSPTKEEAK 647
Query: 1025 VQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQQSNQKRIDKAEVCLWESQGQSILED 1084
+ E K+P K KS P AE K KAE E + E+
Sbjct: 648 SPEKAKSPEKEEAKSPE---KAKS---PVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEE 701
Query: 1085 EKL-LISKTPV-----LPERAK---EENGGQPRAANVCAGQSEELPPKAVASKTENENLN 1135
K +K+PV PE+AK +E P A + + P K A E
Sbjct: 702 AKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEK--AKSPEKAKTL 759
Query: 1136 QIGHQEKKTSSSEENVRGSYNSSNNFQQPLTSRAEVCPWEFETPAQPNAGRSVALPASSA 1195
+ E KT + EE + + P+ + P + ++P + +A P
Sbjct: 760 DVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVK-SPEKAKSPLKEDA----KAPEKEI 814
Query: 1196 LSANKIAGPRKEE 1208
++ P KEE
Sbjct: 815 PKKEEVKSPVKEE 827
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 47.8 bits (112), Expect = 6e-05
Identities = 89/414 (21%), Positives = 158/414 (38%), Gaps = 59/414 (14%)
Query: 788 IRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTES--------- 838
+ N P S G + +E+ N T + ++ +ES
Sbjct: 492 VDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPA 551
Query: 839 QEEETTENSTLESLSGKKLTQKLKEDSEA----ESTESVPLVCKSASAHNLSSEKKTGHP 894
Q + TT+ T+ KK + E+ ES V L S+ + ++ K + P
Sbjct: 552 QSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKP 611
Query: 895 RTSMLQKSLSVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETK 954
KS + K+K + +KS + + ET+ + S+SD +E+
Sbjct: 612 NIKKESKSSPRPTAEKKK------------YKSTSKSSQKSREIIETDTSSSDSDESESL 659
Query: 955 DPAPQNSNPAEEPRKP-------QKSGIMKQQRVNPTTANSDLNPGTTQ-------MKDN 1000
P+ Q E R P ++ +Q+ +P L+P + +K +
Sbjct: 660 PPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKID 719
Query: 1001 FDIGEVCPWEVYDLTPGPVPSESKV-QKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQ 1059
++ P + Y T P + V +KH ++ + + S K K HK +
Sbjct: 720 LNLLTRIPGKPYKETEPPKGEKKNVPEKHTR--EAQKQASEKVSNKGKRKHKNEDDNRAS 777
Query: 1060 QSNQ-KRIDKAEV-----CLWESQGQSILEDEKLLISKT-PVLPERAKEENGGQPRAANV 1112
+S + K DK ES QS +++ LL S PV + K E+G + R +
Sbjct: 778 ESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTIS- 836
Query: 1113 CAGQSEELPPKAVASKT---ENENLNQIGHQEK---KTSSSEENVRGSYNSSNN 1160
QS L + ++K ++N + Q+K KTSSS + V+ SS++
Sbjct: 837 ---QSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSS 887
>gi|58082089 hypothetical protein LOC161394 [Homo sapiens]
Length = 674
Score = 47.4 bits (111), Expect = 8e-05
Identities = 114/550 (20%), Positives = 198/550 (36%), Gaps = 81/550 (14%)
Query: 684 EDELDMGRSGSYLNSSINSAWSEHSLDPEDIRDELKKLYAQLEIYKRKKMITNNPHLQKK 743
E +MG L + ++ E L+P + E K + +++ M T+ +
Sbjct: 110 ETSREMGEFFKDLEAPMDETHKESDLEPPE---EAKPNVTE-DVFLESAMETDPDPVPPT 165
Query: 744 RCSKKGLGRSIMRRITEIPETVSRQCSKEDKEGADHGTAKGTALIRKNPPES------SG 797
+ G ++ R E+ E + E+ H + T L PPE S
Sbjct: 166 ETMSEVSGATVRERNLELLEEETEPGVPEESLRVQH---EETGL---EPPEQTKQDFPSE 219
Query: 798 NTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQEEETTENSTLESLSGKKL 857
G+S EET L+ T ++T+ S TE + E E + LE L +K
Sbjct: 220 KLGESLEET------DLQPPKMTKPETPEETQRES---TEKKRTEPPEQARLEFL--EKE 268
Query: 858 TQKLKEDSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQKSLSVIASAKEKTLGLA 917
+K E++ E E + EK T P +++ K +
Sbjct: 269 PRKSSEEAGLEPPEETQPEVPEEMQRKATEEKGTELP-----ERTKPDFPDHKPR----- 318
Query: 918 GKTQTAGVEE---RTKSQKPLPKDKETNRNHSNSDNTETKDPAPQ---NSNPAEEPRKPQ 971
K+ V E K + P + ++TN + K +P+ SN + P+ P+
Sbjct: 319 -KSTDENVPEPLEEIKLEFPEEESRKTNEETILEQSEMMKPESPEEIRKSNEKKNPQPPE 377
Query: 972 KSGIMKQQRVNPTTANSDLNPGTTQMKDNFDIGEVCPWEV---YDLTPGPVPSESKVQKH 1028
++G + Q +NP T ++ + D E P E + P P +SK
Sbjct: 378 ETGPVLPQEINPQVEEKTQTKPTEKILELPD--ETKPRETHVEFSKEDRPEPIKSKYSVG 435
Query: 1029 VSIVASEMEKNPTFSLKEKSHHKPKAAEVCQQSN-------------QKRIDKAEVCLWE 1075
+ K SL +K + A ++S QK ++ +E C +
Sbjct: 436 NDELEHREPKRGKLSLSDKFRKEYYALGSLRESEESIGTHYEFLQPLQKLLNVSEECSYS 495
Query: 1076 SQGQSILE-----DEKLLISKTPVLPERAKEENGGQPRAANVCAGQSEELPPKAVASKTE 1130
+S E EK ++ + L ER E++ QP + P+ VA
Sbjct: 496 DPSESQTELSEFVHEKEVVDLSQELKERVSEDDETQPEKGTELQFEHLNWDPEEVA---- 551
Query: 1131 NENLNQIGHQEKKTSSSEENVRG----SYNSSNNFQQPLTSRAEVCPWEFETP-----AQ 1181
E ++Q+G + K + G N SN Q +T+ ++ T +
Sbjct: 552 -EWISQLGFPQYKECFITNFISGRKLIHVNCSNLPQMGITNFEDMKAISRHTQELLEIEE 610
Query: 1182 PNAGRSVALP 1191
P RS++LP
Sbjct: 611 PLFKRSISLP 620
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 47.0 bits (110), Expect = 1e-04
Identities = 78/412 (18%), Positives = 160/412 (38%), Gaps = 40/412 (9%)
Query: 746 SKKGLGRSIMRRITEIPETVSRQCSKEDK--EGADHGTAKGTALIRKNPPESSGNTGKSK 803
S G S+++ ++ P + + KE + E T + I ++ +SS N+ S+
Sbjct: 1306 SSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSE 1365
Query: 804 EETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQEEETTENSTLESLSGKKLTQKLKE 863
+ K+R +S+ + + ++ + S+ ES + E +SLS Q KE
Sbjct: 1366 KGKTKDRDYSVLEKENP-----EKRKNSTQPEKESNLDRLNEQGNFKSLS-----QSSKE 1415
Query: 864 DSEAESTESVPLVCKSASAHNLSSEKKTGHPRT--SMLQKSLSVIASAKEKTLGLAGKTQ 921
++ +S S + +KKT + S ++ + K K
Sbjct: 1416 ARTSDKHDSTR--ASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDS 1473
Query: 922 TAGVEERTKSQKPLPK-----DKETNRN-------HSNSDNTETKDPAPQNSNPAEEPRK 969
+G + + + ++ LPK K++N + H + +TK P + + + P K
Sbjct: 1474 ASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCK 1533
Query: 970 PQKSGIMKQQRVNPTTANS---DLNPGTTQMKDNFDIGEVCPWEVYDLTPGPVPSESK-- 1024
++ +++ + ++ N LNP TQ++ G++ + + P P S S
Sbjct: 1534 DREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQI---DKSTVKPKPQLSHSSRL 1590
Query: 1025 ---VQKHVSIVASEMEKNPTFSLKEKS-HHKPKAAEVCQQSNQKRIDKAEVCLWESQGQS 1080
+ + A E + N + S S + + + + K ++KA+ L +
Sbjct: 1591 SSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQ 1650
Query: 1081 ILEDEKLLISKTPVLPERAKEENGGQPRAANVCAGQSEELPPKAVASKTENE 1132
+ S V P R+ +G Q R+ + A +E K K E +
Sbjct: 1651 VGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKK 1702
Score = 35.8 bits (81), Expect = 0.25
Identities = 54/250 (21%), Positives = 83/250 (33%), Gaps = 15/250 (6%)
Query: 734 ITNNPHLQKKRCSKKGLGRSIMRRITEIPETVSRQCSKEDKEGADHGTAKGTALIRKNPP 793
I N+P + +R G G+S R I + S D T P
Sbjct: 836 IRNSPFTRGRREDYVG-GQS--HRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPG 892
Query: 794 ESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQEEETTENSTLESLS 853
+ GN K + K ++S + +T S PT +E +T L S
Sbjct: 893 DGKGNKHKKHRKRRKG-----EESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRD 947
Query: 854 GKKLTQKLKEDSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQKSLSVIASAKEKT 913
T E +AES + KS S + K +K+ S KE
Sbjct: 948 DA--TPVRDEPMDAES-----ITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENI 1000
Query: 914 LGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQNSNPAEEPRKPQKS 973
+ A Q ER +S + P K+ +DNT++ + ++ PRK
Sbjct: 1001 VKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSK 1060
Query: 974 GIMKQQRVNP 983
+ Q P
Sbjct: 1061 SAKEHQETKP 1070
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 47.0 bits (110), Expect = 1e-04
Identities = 78/412 (18%), Positives = 160/412 (38%), Gaps = 40/412 (9%)
Query: 746 SKKGLGRSIMRRITEIPETVSRQCSKEDK--EGADHGTAKGTALIRKNPPESSGNTGKSK 803
S G S+++ ++ P + + KE + E T + I ++ +SS N+ S+
Sbjct: 1340 SSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSE 1399
Query: 804 EETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQEEETTENSTLESLSGKKLTQKLKE 863
+ K+R +S+ + + ++ + S+ ES + E +SLS Q KE
Sbjct: 1400 KGKTKDRDYSVLEKENP-----EKRKNSTQPEKESNLDRLNEQGNFKSLS-----QSSKE 1449
Query: 864 DSEAESTESVPLVCKSASAHNLSSEKKTGHPRT--SMLQKSLSVIASAKEKTLGLAGKTQ 921
++ +S S + +KKT + S ++ + K K
Sbjct: 1450 ARTSDKHDSTR--ASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDS 1507
Query: 922 TAGVEERTKSQKPLPK-----DKETNRN-------HSNSDNTETKDPAPQNSNPAEEPRK 969
+G + + + ++ LPK K++N + H + +TK P + + + P K
Sbjct: 1508 ASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCK 1567
Query: 970 PQKSGIMKQQRVNPTTANS---DLNPGTTQMKDNFDIGEVCPWEVYDLTPGPVPSESK-- 1024
++ +++ + ++ N LNP TQ++ G++ + + P P S S
Sbjct: 1568 DREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQI---DKSTVKPKPQLSHSSRL 1624
Query: 1025 ---VQKHVSIVASEMEKNPTFSLKEKS-HHKPKAAEVCQQSNQKRIDKAEVCLWESQGQS 1080
+ + A E + N + S S + + + + K ++KA+ L +
Sbjct: 1625 SSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQ 1684
Query: 1081 ILEDEKLLISKTPVLPERAKEENGGQPRAANVCAGQSEELPPKAVASKTENE 1132
+ S V P R+ +G Q R+ + A +E K K E +
Sbjct: 1685 VGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKK 1736
Score = 35.8 bits (81), Expect = 0.25
Identities = 54/250 (21%), Positives = 83/250 (33%), Gaps = 15/250 (6%)
Query: 734 ITNNPHLQKKRCSKKGLGRSIMRRITEIPETVSRQCSKEDKEGADHGTAKGTALIRKNPP 793
I N+P + +R G G+S R I + S D T P
Sbjct: 870 IRNSPFTRGRREDYVG-GQS--HRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPG 926
Query: 794 ESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQEEETTENSTLESLS 853
+ GN K + K ++S + +T S PT +E +T L S
Sbjct: 927 DGKGNKHKKHRKRRKG-----EESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRD 981
Query: 854 GKKLTQKLKEDSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQKSLSVIASAKEKT 913
T E +AES + KS S + K +K+ S KE
Sbjct: 982 DA--TPVRDEPMDAES-----ITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENI 1034
Query: 914 LGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQNSNPAEEPRKPQKS 973
+ A Q ER +S + P K+ +DNT++ + ++ PRK
Sbjct: 1035 VKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSK 1094
Query: 974 GIMKQQRVNP 983
+ Q P
Sbjct: 1095 SAKEHQETKP 1104
>gi|40255245 G protein-coupled receptor 51 [Homo sapiens]
Length = 941
Score = 46.2 bits (108), Expect = 2e-04
Identities = 61/338 (18%), Positives = 134/338 (39%), Gaps = 26/338 (7%)
Query: 405 DSPCFVQEDKYLRLAIISFQALCMLLDFVSMLVVYHF----RKAKSIRASGLILLETILF 460
D +++ + + L + S + +L + F R K I+ S + I+
Sbjct: 466 DKTIILEQLRKISLPLYSILSALTILGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIIL 525
Query: 461 GSLLLYFPVVILYFEPS-----TFR--CILLRWARLLGFATVYGTVTLKLHRVLKVFLSR 513
G +L Y + + + S TF C + W +G+ T +G + K RV +F +
Sbjct: 526 GGMLSYASIFLFGLDGSFVSEKTFETLCTVRTWILTVGYTTAFGAMFAKTWRVHAIFKNV 585
Query: 514 TA-------QRIPYMTGGRVMRMLAVILLVVFWFLIGWTSSVCQNLEKQISLIGQGKTSD 566
Q++ + GG ++ L +++ W + + + G+ +
Sbjct: 586 KMKKKIIKDQKLLVIVGGMLLIDLCILIC---WQAVDPLRRTVEKYSMEPDPAGRDISIR 642
Query: 567 HLIFNM--CLIDRWDYMTAVAEFLFLLWGVYLCYAVRTVP-SAFHEPRYMAVAVHNELII 623
L+ + + W + + L +L+G +L + R V A ++ +Y+ ++V+N I+
Sbjct: 643 PLLEHCENTHMTIWLGIVYAYKGLLMLFGCFLAWETRNVSIPALNDSKYIGMSVYNVGIM 702
Query: 624 SAIFHTIRFVLASRLQSDWMLMLYFAHTHLTVTVTIGLLLIPKFSHSSNNPRDDIATEAY 683
I + F+ +R Q + + T+T+ L+ +PK NP +
Sbjct: 703 CIIGAAVSFL--TRDQPNVQFCIVALVIIFCSTITLCLVFVPKLITLRTNPDAATQNRRF 760
Query: 684 EDELDMGRSGSYLNSSINSAWSEHSLDPEDIRDELKKL 721
+ + + S ++S+ S + E ++ E +L
Sbjct: 761 QFTQNQKKEDSKTSTSVTSVNQASTSRLEGLQSENHRL 798
>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
sapiens]
Length = 1393
Score = 45.1 bits (105), Expect = 4e-04
Identities = 81/418 (19%), Positives = 151/418 (36%), Gaps = 57/418 (13%)
Query: 766 SRQCSKEDKEGADHGTAKGTALIRKNPPESSGNTGKSKEETLKNRV--FSLKKSHSTYDH 823
+ + + E +H A+ T L +N S +++E T + F + + +
Sbjct: 791 NEKTTSSSAEPTEH--AERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENREST 848
Query: 824 VRDQTEESSSLPTESQEEETTENSTL---ESLSGKKLTQKLKED---SEAESTESVPLVC 877
++T + PTE++E EN+TL E +++T E S AE TE+
Sbjct: 849 ANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLANEKTTLSPAEPTENGERTP 908
Query: 878 KSASAHNLSSEKKTGHPRTSMLQKSLSVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPK 937
+ SS + T H + L ++ + A+ G ER ++K P
Sbjct: 909 FTNEKTTPSSAEPTEHGERTPLANEITTPSRAEPTEHG-----------ERIANEKATPS 957
Query: 938 DKETNRNHSNSDNTETKDPAPQNSNPAEEPRKPQKSGIMKQQRVNPTTANSDLNPGTTQM 997
+ + + T +D P ++ P E +++ + + T +++ T
Sbjct: 958 PAKPT---EHGETTVNEDTTPSSAEPTE---NGERTPLANENTTTSPTESTEHGERTANE 1011
Query: 998 KDNFDIGEVCPWEVYDLTPG----PVPSESKVQKHVSIVASEMEKNPTFSLKEKSHHKPK 1053
K E P E + TP +PS +K +H + S E +K H
Sbjct: 1012 KTTPSPAE--PTEHGERTPSANEKTIPSPAKPTEHEEMTPSANENTTPSPVKPTEH---- 1065
Query: 1054 AAEVCQQSNQK-------------RIDKAEVCLWESQGQSILEDEKLLISKTPVLPERAK 1100
E +N+K + A + S + E+ + A+
Sbjct: 1066 -GEKTTLANEKITLSPEGPTEHGAKTTSANEKITPSLAKPTEHGERTTSPNDKITSSAAE 1124
Query: 1101 E-ENGGQPRAANVCAGQSEELPPKAVASKTENENLNQI-----GHQEKKTSSSEENVR 1152
E+ + +ANV E A + +E + Q+ H EK TS++E+ R
Sbjct: 1125 STEHRDRATSANVITPAPAEPIKHAKRTTLAHEKMTQVTEKSTEHPEKTTSTTEKTTR 1182
Score = 43.5 bits (101), Expect = 0.001
Identities = 118/578 (20%), Positives = 199/578 (34%), Gaps = 112/578 (19%)
Query: 669 HSSNNPRDDIATEAYEDELDMGRSGSYLNSSINSAWSEHSLDPEDIRDELKKLYAQLEIY 728
H S+ + + E+ + G+ N + S+DP D K+
Sbjct: 108 HKSSTDNHEAPPTSEENSSNQGKDPMIRN--------QRSVDPADSTTTHKESAG----- 154
Query: 729 KRKKMITNNPHLQKKRCSKKGLGRS-IMRRITEIPETVSRQCSKEDKEG-ADHGTAKGTA 786
KK IT P K C K G+S + R+ + + + S DK + H T
Sbjct: 155 --KKHITPAPK-SKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSF- 210
Query: 787 LIRKNPPESSGNTG-KSKEETLKNRVFSLKKSHSTYDHV-----RDQTEESSSLPTESQE 840
+SGN+ K K + ++ + K+ TY ++TE+S + +
Sbjct: 211 -------HNSGNSQTKQKSTSFPEKITAASKT--TYKTTGTPEESEKTEDSRTTVASDKL 261
Query: 841 EETTENSTLESLSGKKLTQKLKEDSEAESTESVPLVCKSASAHNLSS--EKKTGHPRTSM 898
T + E++S +LTQ L E +E ++A+ +N S E RT+
Sbjct: 262 LTKTTKNIQETISANELTQSLAEPTEHGG--------RTANENNTPSPAEPTENRERTAN 313
Query: 899 LQKSLSVIASAKEKTLGLAGKTQTAGVEERTKSQK--PLPKDKETNRNHSNSDNTETKDP 956
+LS + + ERT ++ P P NR + ++NT
Sbjct: 314 ENTTLSPAEPIENR--------------ERTANENTAPFPAGPTENREMTANENTTLFPA 359
Query: 957 AP-------QNSNPAEEPRKPQKSGIMKQQRVNPTTANSDLNP-------------GTTQ 996
P N N P +P + G ++ N T S P T+
Sbjct: 360 EPTEHGERTANENTTPSPAEPTEHG---ERTANENTTPSPAEPTEHGERTPFANDKTTSS 416
Query: 997 MKDNFDIGEVCPWEVYDLTPGP---------------VPSESKVQKHVSIVASEMEK--- 1038
++ + GE P + TP P PS + ++ A+E
Sbjct: 417 SAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSP 476
Query: 1039 -NPTFSLKEKSHHKPKAAEVCQQSNQKRIDKAEVCLWESQGQSILEDEKLLISKTPVLPE 1097
PT + + ++ K + N +R A S + E+ ++ P
Sbjct: 477 VEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPS 536
Query: 1098 RAKEENGGQPRAANVCAGQSEELPPKAVASKTENENLNQIGHQEKKTSSSEENVRGSYNS 1157
A E + R AN E + A TEN + + +++ S +E G
Sbjct: 537 PA-EPTENRERTAN-------EKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTP 588
Query: 1158 SNNFQQPLTSRAEVCPWEFETP-AQPNAGRSVALPASS 1194
N ++ +S AE E TP A N S A P +
Sbjct: 589 FAN-EKTTSSSAEPTEHEERTPLANENTTPSPAEPTEN 625
Score = 36.2 bits (82), Expect = 0.20
Identities = 43/197 (21%), Positives = 78/197 (39%), Gaps = 18/197 (9%)
Query: 792 PPESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQEEETTENSTLES 851
P E+ T + E+T + + T + T S + PTE++E EN+T S
Sbjct: 580 PTENGQRTPFANEKTTSSSAEPTEHEERT-PLANENTTPSPAEPTENRERTANENTT-PS 637
Query: 852 LSGKKLTQKLKEDSE-----AESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQKSLSVI 906
+G +++ + + AE TE+ + + + + G +K+ S
Sbjct: 638 PAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSS 697
Query: 907 ASAKE--KTLGLAGKTQTAGVEERTKSQK--------PLPKDKETNRNHSNSDNTETKDP 956
A E + LA + T E T++++ P P + NR + ++NT T P
Sbjct: 698 AEPTEHGERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRERTANENT-TPSP 756
Query: 957 APQNSNPAEEPRKPQKS 973
A N P +K+
Sbjct: 757 AQPTENGDRTPLANEKT 773
>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
Length = 4069
Score = 45.1 bits (105), Expect = 4e-04
Identities = 83/369 (22%), Positives = 140/369 (37%), Gaps = 50/369 (13%)
Query: 795 SSGNTG-------KSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQEEETTENS 847
SSGNT S+E L SL + + ++ + E S + +ES E N+
Sbjct: 1968 SSGNTETLSSKSYSSEEVKLAEEPKSLVLAGNVERNIAEGKEIHSLMESESLLLEKA-NT 2026
Query: 848 TLESLSGKKLTQKLKEDSEAESTESVP-LVCKSASAHNLSSEKKTGHPRTSMLQKSLSVI 906
L S + +K+K E + V L + + +SS KT H ++ +L
Sbjct: 2027 ELSWPSKEDSQEKIKLPPERFFQKPVSGLSVEQVKSETISSSVKTAHFPAEGVEPALGNE 2086
Query: 907 ASA--------KEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAP 958
A +EK L + Q+ +++ + +KP P+ K + P
Sbjct: 2087 KEAHRSTPPFPEEKPLEESKMVQSKVIDDADEGKKPSPEVKIPTQR------------KP 2134
Query: 959 QNSNPAEEPRKPQKSGIMKQQRVNPTTANSDL-----NPGTTQMK---DNFDIGEVCP-- 1008
+S A EP+ P+ + + P A DL G + K + G P
Sbjct: 2135 ISSIHAREPQSPESPEVTQNPPTQPKVAKPDLPEEKGKKGISSFKSWMSSLFFGSSTPDN 2194
Query: 1009 --WEVYDLTPGPVPSESKVQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQQSNQKRI 1066
E DL P PS V+K V+++ E F++ EK A + K
Sbjct: 2195 KVAEQEDLETQPSPS---VEKAVTVIDPEGTIPTNFNVAEK-----PADHSLSEVKLKTA 2246
Query: 1067 DKAEVCLWES-QGQSILEDEKLLISKTPVLPERAKEENGGQPRAANVCAGQSEELPPKAV 1125
D+ L +S GQ++ E +L + + + E + +G SEE+ +V
Sbjct: 2247 DEPRGTLVKSGDGQNVKEKSMILSNVEDLQQPKFISEVSREDYGKKEISGDSEEMNINSV 2306
Query: 1126 ASKTENENL 1134
+ + ENL
Sbjct: 2307 VTSADGENL 2315
Score = 31.2 bits (69), Expect = 6.3
Identities = 65/283 (22%), Positives = 111/283 (39%), Gaps = 33/283 (11%)
Query: 829 EESSSLPTESQEEETTENSTLESLSGKKLTQKLKEDSEAESTESVPLVCKSASAHNLSSE 888
E SS S+ E+ + +L S+S L E E +P++ S+S H+ SE
Sbjct: 1428 ETSSKHLAWSEAEKEIKFDSLPSVSSIAEHSVLSEVEAKEVKAGLPVIKTSSSQHSDKSE 1487
Query: 889 KKTGHPRTSMLQKSL---SVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNH 945
+ + +L ++ + S+++K+L T+ V E + + PL E +
Sbjct: 1488 EARVEDKQDLLFSTVCDSERLVSSQKKSL-----MSTSEVLE-PEHELPLSLWGEIKKK- 1540
Query: 946 SNSDNTETKDPAPQNSNPAEEPRKPQKSGIMKQQRVNPTTAN--SDLNPGTTQMKDNFDI 1003
ET+ P+ QN +PA + P K + +P N S L P + D+ +
Sbjct: 1541 ------ETELPSSQNVSPASKHIIP-KGKDEETASSSPELENLASGLAPTLLLLSDDKNK 1593
Query: 1004 GEVCPWEVYDLTPGPVPSESKVQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQQSNQ 1063
V EV G PSE + + +E+ P K+ H+P
Sbjct: 1594 PAV---EVSSTAQGDFPSEKQ-----DVALAELSLEPE---KKDKPHQPLELPNAGSEFS 1642
Query: 1064 KRIDKAEVCLWESQGQS-ILEDEKLLISKTP--VLPERAKEEN 1103
+ + + Q +S I E E ++ K P + KEEN
Sbjct: 1643 SDLGRQSGSIGTKQAKSPITETEDSVLEKGPAELRSREGKEEN 1685
>gi|4504141 glutamate receptor, metabotropic 4 [Homo sapiens]
Length = 912
Score = 44.7 bits (104), Expect = 5e-04
Identities = 63/268 (23%), Positives = 108/268 (40%), Gaps = 35/268 (13%)
Query: 416 LRLAIISFQA-LCMLLDFVSMLVVYHFRKAKSIRASGLILLETILFGSLLLYFPVVILYF 474
L LA++ A L +++ FV + ++ASG L +L G L Y ++
Sbjct: 592 LFLAVVGIAATLFVVITFV------RYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIA 645
Query: 475 EPSTFRCILLRWARLLGFATVYGTVTLKLHRVLKVF----LSRTAQRI--PYMTGGRVMR 528
EP C L R LG + Y + K +R+ ++F S +A R P
Sbjct: 646 EPDLGTCSLRRIFLGLGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFS 705
Query: 529 MLAVILL-VVFWFLIGWTSSVCQNLEKQISLIGQGKTSDHLIFNMCLIDRWDY-MTAVAE 586
++++ LL + WF++ + SV + Q + D D + +
Sbjct: 706 LISLQLLGICVWFVVDPSHSV-------VDFQDQRTLDPRFARGVLKCDISDLSLICLLG 758
Query: 587 FLFLLWGVYLCYAVRT--VPSAFHEPRYMAVAVHNELIISAIFHTIRFVLASRLQSDWML 644
+ LL YA++T VP F+E + + ++ I+ F I F +
Sbjct: 759 YSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADK---- 814
Query: 645 MLYFAHTHLTV------TVTIGLLLIPK 666
LY T LTV +V++G+L +PK
Sbjct: 815 -LYIQTTTLTVSVSLSASVSLGMLYMPK 841
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 44.7 bits (104), Expect = 5e-04
Identities = 42/215 (19%), Positives = 93/215 (43%), Gaps = 11/215 (5%)
Query: 789 RKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQEEETTENST 848
+KN +SS + ++ K+ +KK+ D +D +++ S ES + + T
Sbjct: 289 KKNAKKSSDAESEDSKDAKKDSK-KVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDT 347
Query: 849 LESLSGKKLTQKLKEDSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQKSLSVIAS 908
KK +KLK+D + + T+ P + S + + + K+
Sbjct: 348 ------KKDKKKLKKDDKKKDTKKYPESTDTESGD--AKDARNDSRNLKKASKNDDKKKD 399
Query: 909 AKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQNSNPAEEPR 968
AK+ T +++ E + K +K KD +T+ S ++ E+ D + +++ +
Sbjct: 400 AKKITFSTDSESELESKESQ-KDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGK 458
Query: 969 KPQKSGIMKQQRVNPTTANSDLNPGTTQMKDNFDI 1003
K +K G K + + ++ N +T+M+ + ++
Sbjct: 459 KDEKKG-KKDSKKDDKKKDAKKNAESTEMESDLEL 492
Score = 42.7 bits (99), Expect = 0.002
Identities = 66/336 (19%), Positives = 128/336 (38%), Gaps = 32/336 (9%)
Query: 666 KFSHSSNNPRDDIATEAYEDELDMGRSGSYLNSSINSAWSEHSLDPEDIR------DELK 719
+F H+ NNP+ D+ + N I+ SE+SL+ + + DE
Sbjct: 212 EFLHTKNNPKKDL------------KRSKTSNDPISEICSENSLNVDFLMLVGQSDDESI 259
Query: 720 KLYAQLEIYKRKKMITNNPHLQKKRCSKKGLGRSIMRRITEIPETVSRQCSKEDKEGADH 779
A L Y + + N L+ + +KK ++ + + E+ + +K+D +
Sbjct: 260 NFDAWLRNYSQNN--SKNYSLKYTKYTKKDTKKNAKK--SSDAESEDSKDAKKDSKKVKK 315
Query: 780 GTAKGTAL--IRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTE 837
K ++K+ + +G SK+E + KK D +D + S TE
Sbjct: 316 NVKKDDKKKDVKKDTESTDAESGDSKDERKDTK--KDKKKLKKDDKKKDTKKYPESTDTE 373
Query: 838 SQEEETTENSTLESLSGKKLTQKLKEDSEAE-STESVPLVCKSASAHNLSSEKKTGHPRT 896
S + + N + K K K+ + ST+S + S + +KK
Sbjct: 374 SGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDN 433
Query: 897 SMLQKSLSVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETK-D 955
K+ A + G + K G ++ K +K KD + N+++TE + D
Sbjct: 434 KKSVKNDEESTDADSEPKGDSKK----GKKDEKKGKKDSKKDDKKKDAKKNAESTEMESD 489
Query: 956 PAPQNSNPAEEPRKPQKSGIMKQQRVNPTTANSDLN 991
+ + +K K I K R + + +++ +
Sbjct: 490 LELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFD 525
>gi|194306543 oxidation resistance 1 isoform 2 [Homo sapiens]
Length = 839
Score = 44.7 bits (104), Expect = 5e-04
Identities = 50/212 (23%), Positives = 83/212 (39%), Gaps = 23/212 (10%)
Query: 788 IRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHV--RDQTEESSSLPTESQEEETTE 845
IR +S+ +S EE+L VF+ + + + D+ + S S+ +T
Sbjct: 308 IRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVN 367
Query: 846 NSTLESLSGKKLTQ----KLKEDSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQK 901
+ +ESL+ K + L+ D+E ST V +C +NL K +
Sbjct: 368 QAEVESLTVKSESTGTPGHLRSDTE-HSTNEVGTLCHKTDLNNLEMAIKE-----DQIAD 421
Query: 902 SLSVIASAKEKTLGLAGKTQTAGV--------EERTKSQKPLPKDKETNRNHSNSDNTET 953
+ I+ KE + + G + EE K P + E + S + +
Sbjct: 422 NFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQG 481
Query: 954 KDPAPQNSNPAEEPRKPQKSGIM---KQQRVN 982
K+ + AEE RK K+ M KQQR N
Sbjct: 482 KEQNQDSQTEAEELRKLWKTHTMQQTKQQREN 513
>gi|194306541 oxidation resistance 1 isoform 1 [Homo sapiens]
Length = 846
Score = 44.7 bits (104), Expect = 5e-04
Identities = 50/212 (23%), Positives = 83/212 (39%), Gaps = 23/212 (10%)
Query: 788 IRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHV--RDQTEESSSLPTESQEEETTE 845
IR +S+ +S EE+L VF+ + + + D+ + S S+ +T
Sbjct: 315 IRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVN 374
Query: 846 NSTLESLSGKKLTQ----KLKEDSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQK 901
+ +ESL+ K + L+ D+E ST V +C +NL K +
Sbjct: 375 QAEVESLTVKSESTGTPGHLRSDTE-HSTNEVGTLCHKTDLNNLEMAIKE-----DQIAD 428
Query: 902 SLSVIASAKEKTLGLAGKTQTAGV--------EERTKSQKPLPKDKETNRNHSNSDNTET 953
+ I+ KE + + G + EE K P + E + S + +
Sbjct: 429 NFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQG 488
Query: 954 KDPAPQNSNPAEEPRKPQKSGIM---KQQRVN 982
K+ + AEE RK K+ M KQQR N
Sbjct: 489 KEQNQDSQTEAEELRKLWKTHTMQQTKQQREN 520
>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical
region 1 [Homo sapiens]
Length = 1400
Score = 44.3 bits (103), Expect = 7e-04
Identities = 118/576 (20%), Positives = 199/576 (34%), Gaps = 108/576 (18%)
Query: 669 HSSNNPRDDIATEAYEDELDMGRSGSYLNSSINSAWSEHSLDPEDIRDELKKLYAQLEIY 728
H S+ + + E+ + G+ N + S+DP D K+
Sbjct: 170 HKSSTDNHEAPPTSEENSSNQGKDPMIRN--------QRSVDPADSTTTHKESAG----- 216
Query: 729 KRKKMITNNPHLQKKRCSKKGLGRS-IMRRITEIPETVSRQCSKEDKEG-ADHGTAKGTA 786
KK IT P K C K G+S + R+ + + + S DK + H T
Sbjct: 217 --KKHITPAPK-SKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSF- 272
Query: 787 LIRKNPPESSGNTG-KSKEETLKNRVFSLKKSHSTYDHV-----RDQTEESSSLPTESQE 840
+SGN+ K K + ++ + K+ TY ++TE+S + +
Sbjct: 273 -------HNSGNSQTKQKSTSFPEKITAASKT--TYKTTGTPEESEKTEDSRTTVASDKL 323
Query: 841 EETTENSTLESLSGKKLTQKLKEDSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQ 900
T + E++S +LTQ L E +E ++A+ +N S + R
Sbjct: 324 LTKTTKNIQETISANELTQSLAEPTEHGG--------RTANENNTPSPAEPTENRER--- 372
Query: 901 KSLSVIASAKEKTLGLAGKTQTAGVEERTKSQK--PLPKDKETNRNHSNSDNTETKDPAP 958
+ + TL A T+ ERT ++ P P NR + ++NT P
Sbjct: 373 ------TANENTTLSPAEPTEN---RERTANENTAPFPAGPTENREMTANENTTLFPAEP 423
Query: 959 -------QNSNPAEEPRKPQKSGIMKQQRVNPTTANSDLNP-------------GTTQMK 998
N N P +P + G ++ N T S P T+
Sbjct: 424 TEHGERTANENTTPSPAEPTEHG---ERTANENTTPSPAEPTEHGERTPFANDKTTSSSA 480
Query: 999 DNFDIGEVCPWEVYDLTPGP---------------VPSESKVQKHVSIVASEMEK----N 1039
++ + GE P + TP P PS + ++ A+E
Sbjct: 481 ESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVE 540
Query: 1040 PTFSLKEKSHHKPKAAEVCQQSNQKRIDKAEVCLWESQGQSILEDEKLLISKTPVLPERA 1099
PT + + ++ K + N +R A S + E+ ++ P A
Sbjct: 541 PTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPA 600
Query: 1100 KEENGGQPRAANVCAGQSEELPPKAVASKTENENLNQIGHQEKKTSSSEENVRGSYNSSN 1159
E + R AN E + A TEN + + +++ S +E G
Sbjct: 601 -EPTENRERTAN-------EKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFA 652
Query: 1160 NFQQPLTSRAEVCPWEFETP-AQPNAGRSVALPASS 1194
N ++ +S AE E TP A N S A P +
Sbjct: 653 N-EKTTSSSAEPTEHEERTPLANENTTPSPAEPTEN 687
Score = 39.3 bits (90), Expect = 0.023
Identities = 47/200 (23%), Positives = 79/200 (39%), Gaps = 24/200 (12%)
Query: 792 PPESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQEEETTENSTLES 851
P E+ T + E+T + + T + T S + PTE++E EN+T S
Sbjct: 642 PTENGQRTPFANEKTTSSSAEPTEHEERT-PLANENTTPSPAEPTENRERTANENTT-PS 699
Query: 852 LSGKKLTQKLKEDSE-----AESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQKSLSVI 906
+G +++ + + AE TE+ + + + + G +K+ S
Sbjct: 700 PAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSS 759
Query: 907 ASAKE-----------KTLGLAGKTQTAGVEERTKSQK--PLPKDKETNRNHSNSDNTET 953
A E TL AG T+ ERT ++K P P + NR + ++NT T
Sbjct: 760 AEPTEHGERTPLANENTTLSPAGPTEN---RERTANEKTTPFPAEPTENRERTANENT-T 815
Query: 954 KDPAPQNSNPAEEPRKPQKS 973
PA N P +K+
Sbjct: 816 PSPAQPTENGDRTPLANEKT 835
Score = 34.7 bits (78), Expect = 0.57
Identities = 43/211 (20%), Positives = 77/211 (36%), Gaps = 22/211 (10%)
Query: 766 SRQCSKEDKEGADHGTAKGTALIRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHVR 825
+ + + E +HG + T L +N S +++E T + + R
Sbjct: 752 NEKTTSSSAEPTEHG--ERTPLANENTTLSPAGPTENRERTANEKTTPFPAEPTEN---R 806
Query: 826 DQTEESSSLPTESQEEETTENSTLESLSGKKLTQKLKEDSE---------AESTESVPLV 876
++T ++ P+ +Q TEN L+ +K T L E +E ++T S
Sbjct: 807 ERTANENTTPSPAQP---TENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEP 863
Query: 877 CKSASAHNLSSEKKTGHPRTSMLQKSLSVIASAKEKTLGLAGKTQTAGVEERTKSQKPLP 936
+ A L++E T P + +A EKT + + P P
Sbjct: 864 TEHAERTPLANENTTSSPAEPTENRE----RTANEKTTQFPAEPTENRESTANEKTTPFP 919
Query: 937 KDKETNRNHSNSDNTETKDPAPQNSNPAEEP 967
+ NR + ++NT T PA + P
Sbjct: 920 AEPTENREWTANENT-TLSPAEPTEHEEMTP 949
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 43.5 bits (101), Expect = 0.001
Identities = 77/371 (20%), Positives = 136/371 (36%), Gaps = 61/371 (16%)
Query: 826 DQTEESSSLPTESQEEETTENSTLESLSGKKLTQKLKEDSEAESTESVPLVCKSASAHNL 885
DQ+++ + P + + + SG + E T SV ++ ++
Sbjct: 9 DQSDDGGATPVQDERD-----------SGSDGEDDVNEQHSGSDTGSVERHSENETSDRE 57
Query: 886 SSEKKTGHPRTSMLQKSLSVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNH 945
K H S + L++ AS E K + EER + ++++ N++
Sbjct: 58 DGLPKGHHVTDSENDEPLNLNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHG 117
Query: 946 SNSDNTETKDPAPQNSNPAEEPRKPQKSGIMKQQRVNPTTANSDLNPGTTQMKDNFDIGE 1005
S+S++ ET+ +S N +L G +N D+G+
Sbjct: 118 SDSESEETRKLPGSDSE------------------------NEELLNGHASDSENEDVGK 153
Query: 1006 --VCPWEVYDLTPGPV-PSESKVQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQQSN 1062
E+ +L P SE++ I SE E+ P + + +P + S
Sbjct: 154 HPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPKPRM-SDSE 212
Query: 1063 QKRIDKAEVCLWESQGQSILEDEKLLISKTPVLPERAKEENGGQPRAANVCAGQSEELPP 1122
+ + K +V ES+ P + + EN P+ + +SE+ PP
Sbjct: 213 SEELPKPQVSDSESE--------------EPPRHQASDSENEELPK-PRISDSESED-PP 256
Query: 1123 KAVASKTENENLNQIGHQEKKTSSSEENVRGSYNSSNNFQQPLTSRAEVCPWEFETPAQP 1182
+ AS +ENE L + S SE+ R + S N + P + V E E P +
Sbjct: 257 RHQASDSENEELPK---PRISDSESEDPPRNQASDSENEELP---KPRVSDSESEGPQKG 310
Query: 1183 NAGRSVALPAS 1193
A S AS
Sbjct: 311 PASDSETEDAS 321
Score = 38.1 bits (87), Expect = 0.051
Identities = 72/374 (19%), Positives = 126/374 (33%), Gaps = 47/374 (12%)
Query: 796 SGNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQEEETTENSTLESL--- 852
+G+ + E +R L K H D D+ ++ +ES+E ++S ES
Sbjct: 42 TGSVERHSENETSDREDGLPKGHHVTDSENDEPLNLNASDSESEELHRQKDSDSESEERA 101
Query: 853 ------SGKKLTQKLKEDSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQKSLSVI 906
S + + DSE+E T +P + + + E GH S +
Sbjct: 102 EPPASDSENEDVNQHGSDSESEETRKLP------GSDSENEELLNGHASDSENEDVGKHP 155
Query: 907 ASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQNSNPAEE 966
AS E +EE KS + ++ + + +E + + EE
Sbjct: 156 ASDSE-------------IEELQKSPASDSETEDALKPQISDSESEEPPRHQASDSENEE 202
Query: 967 PRKPQKSGIMKQQRVNPTTANSDLNPGTTQMKDNFDIGEVCPWEVYDLTPGPVPSESKVQ 1026
P KP+ S ++ P ++S+ + + E+ + D SES+
Sbjct: 203 PPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISD-------SESEDP 255
Query: 1027 KHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQQSNQKRIDKAEVCLWESQG-------Q 1079
SE E+ P + + P + N++ + K V ES+G
Sbjct: 256 PRHQASDSENEELPKPRISDSESEDPPRNQASDSENEE-LPKPRVSDSESEGPQKGPASD 314
Query: 1080 SILEDEKLLISKTPVLPERAKEENGGQPRAANVCAGQSEELPPKAVASKTENENLNQIGH 1139
S ED K + +E G N + K S E H
Sbjct: 315 SETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEE----EH 370
Query: 1140 QEKKTSSSEENVRG 1153
+++K S E+ G
Sbjct: 371 KKQKMDSDEDEKEG 384
>gi|187960069 glutamate receptor, metabotropic 8 isoform b precursor
[Homo sapiens]
Length = 908
Score = 43.1 bits (100), Expect = 0.002
Identities = 63/260 (24%), Positives = 108/260 (41%), Gaps = 27/260 (10%)
Query: 423 FQALCMLLDFVSMLVVY-HFRKAKSIRASGLILLETILFGSLLLYFPVVILYFEPSTFRC 481
F A+ ++ ++V + + +RASG L +L G L Y ++ P T C
Sbjct: 589 FVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIIC 648
Query: 482 ILLRWARLLGFATVYGTVTLKLHRVLKVF----LSRTAQRIPYMTGGRVM--RMLAVILL 535
R LG Y + K +R+ ++F S TA + V+ +++V LL
Sbjct: 649 SFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLL 708
Query: 536 VVF-WFLIGWTSSVCQNLEKQISLIGQGKTSDHLIFNMCLIDRWDYMTAVAEFLFLLWGV 594
VF WF++ + E++ + K L C I + ++ + LL
Sbjct: 709 GVFVWFVVDPPHIIIDYGEQR--TLDPEKARGVL---KCDISDLSLICSLG-YSILLMVT 762
Query: 595 YLCYAVRT--VPSAFHEPRYMAVAVHNELIISAIFHTIRFVLASRLQSDWMLMLYFAHTH 652
YA++T VP F+E + + ++ II F I F A + +Y T
Sbjct: 763 CTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEK-----MYIQTTT 817
Query: 653 LTV------TVTIGLLLIPK 666
LTV +V++G+L +PK
Sbjct: 818 LTVSMSLSASVSLGMLYMPK 837
>gi|187960067 glutamate receptor, metabotropic 8 isoform a precursor
[Homo sapiens]
Length = 908
Score = 43.1 bits (100), Expect = 0.002
Identities = 63/260 (24%), Positives = 108/260 (41%), Gaps = 27/260 (10%)
Query: 423 FQALCMLLDFVSMLVVY-HFRKAKSIRASGLILLETILFGSLLLYFPVVILYFEPSTFRC 481
F A+ ++ ++V + + +RASG L +L G L Y ++ P T C
Sbjct: 589 FVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIIC 648
Query: 482 ILLRWARLLGFATVYGTVTLKLHRVLKVF----LSRTAQRIPYMTGGRVM--RMLAVILL 535
R LG Y + K +R+ ++F S TA + V+ +++V LL
Sbjct: 649 SFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLL 708
Query: 536 VVF-WFLIGWTSSVCQNLEKQISLIGQGKTSDHLIFNMCLIDRWDYMTAVAEFLFLLWGV 594
VF WF++ + E++ + K L C I + ++ + LL
Sbjct: 709 GVFVWFVVDPPHIIIDYGEQR--TLDPEKARGVL---KCDISDLSLICSLG-YSILLMVT 762
Query: 595 YLCYAVRT--VPSAFHEPRYMAVAVHNELIISAIFHTIRFVLASRLQSDWMLMLYFAHTH 652
YA++T VP F+E + + ++ II F I F A + +Y T
Sbjct: 763 CTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEK-----MYIQTTT 817
Query: 653 LTV------TVTIGLLLIPK 666
LTV +V++G+L +PK
Sbjct: 818 LTVSMSLSASVSLGMLYMPK 837
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,431,446
Number of Sequences: 37866
Number of extensions: 2387120
Number of successful extensions: 11818
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 409
Number of HSP's that attempted gapping in prelim test: 10645
Number of HSP's gapped (non-prelim): 1423
length of query: 1215
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1101
effective length of database: 13,930,794
effective search space: 15337804194
effective search space used: 15337804194
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.