Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 91206396
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|91206396 taste receptor, type 1, member 3 [Homo sapiens]
(852 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|91206396 taste receptor, type 1, member 3 [Homo sapiens] 1745 0.0
gi|29294615 sweet taste receptor T1r isoform b [Homo sapiens] 434 e-121
gi|112807234 G protein-coupled receptor, family C, group 6, memb... 392 e-109
gi|37577159 calcium-sensing receptor [Homo sapiens] 391 e-108
gi|112789566 taste receptor, type 1, member 2 [Homo sapiens] 379 e-105
gi|66529100 glutamate receptor, metabotropic 2 isoform a precurs... 233 6e-61
gi|29294617 sweet taste receptor T1r isoform a [Homo sapiens] 232 1e-60
gi|110611176 glutamate receptor, metabotropic 6 precursor [Homo ... 213 5e-55
gi|4504141 glutamate receptor, metabotropic 4 [Homo sapiens] 211 3e-54
gi|46358417 glutamate receptor, metabotropic 3 precursor [Homo s... 209 9e-54
gi|32528268 glutamate receptor, metabotropic 7 isoform b precurs... 209 1e-53
gi|4504147 glutamate receptor, metabotropic 7 isoform a precurso... 209 1e-53
gi|29294619 sweet taste receptor T1r isoform c [Homo sapiens] 207 4e-53
gi|187960069 glutamate receptor, metabotropic 8 isoform b precur... 201 2e-51
gi|187960067 glutamate receptor, metabotropic 8 isoform a precur... 201 2e-51
gi|166999223 glutamate receptor, metabotropic 1 isoform beta pre... 194 2e-49
gi|166999098 glutamate receptor, metabotropic 1 isoform alpha pr... 194 2e-49
gi|219842343 glutamate receptor, metabotropic 5 isoform a precur... 126 7e-29
gi|4504143 glutamate receptor, metabotropic 5 isoform b precurso... 126 7e-29
gi|29294621 sweet taste receptor T1r isoform d [Homo sapiens] 91 6e-18
gi|167000400 gamma-aminobutyric acid (GABA) B receptor 1 isoform... 59 2e-08
gi|11497612 gamma-aminobutyric acid (GABA) B receptor 1 isoform ... 59 2e-08
gi|10835015 gamma-aminobutyric acid (GABA) B receptor 1 isoform ... 59 2e-08
gi|40255245 G protein-coupled receptor 51 [Homo sapiens] 56 1e-07
gi|134152694 guanylate cyclase 2F [Homo sapiens] 44 6e-04
gi|11496971 NMDA receptor 1 isoform NR1-1 precursor [Homo sapiens] 43 0.001
gi|11038637 NMDA receptor 1 isoform NR1-3 precursor [Homo sapiens] 43 0.001
gi|11038635 NMDA receptor 1 isoform NR1-2 precursor [Homo sapiens] 43 0.001
gi|194248052 glutamate receptor, metabotropic 2 isoform b [Homo ... 40 0.007
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ... 35 0.23
>gi|91206396 taste receptor, type 1, member 3 [Homo sapiens]
Length = 852
Score = 1745 bits (4520), Expect = 0.0
Identities = 852/852 (100%), Positives = 852/852 (100%)
Query: 1 MLGPAVLGLSLWALLHPGTGAPLCLSQQLRMKGDYVLGGLFPLGEAEEAGLRSRTRPSSP 60
MLGPAVLGLSLWALLHPGTGAPLCLSQQLRMKGDYVLGGLFPLGEAEEAGLRSRTRPSSP
Sbjct: 1 MLGPAVLGLSLWALLHPGTGAPLCLSQQLRMKGDYVLGGLFPLGEAEEAGLRSRTRPSSP 60
Query: 61 VCTRFSSNGLLWALAMKMAVEEINNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKA 120
VCTRFSSNGLLWALAMKMAVEEINNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKA
Sbjct: 61 VCTRFSSNGLLWALAMKMAVEEINNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKA 120
Query: 121 GSRDIAAYCNYTQYQPRVLAVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETF 180
GSRDIAAYCNYTQYQPRVLAVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETF
Sbjct: 121 GSRDIAAYCNYTQYQPRVLAVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETF 180
Query: 181 PSFFRTVPSDRVQLTAAAELLQEFGWNWVAALGSDDEYGRQGLSIFSALAAARGICIAHE 240
PSFFRTVPSDRVQLTAAAELLQEFGWNWVAALGSDDEYGRQGLSIFSALAAARGICIAHE
Sbjct: 181 PSFFRTVPSDRVQLTAAAELLQEFGWNWVAALGSDDEYGRQGLSIFSALAAARGICIAHE 240
Query: 241 GLVPLPRADDSRLGKVQDVLHQVNQSSVQVVLLFASVHAAHALFNYSISSRLSPKVWVAS 300
GLVPLPRADDSRLGKVQDVLHQVNQSSVQVVLLFASVHAAHALFNYSISSRLSPKVWVAS
Sbjct: 241 GLVPLPRADDSRLGKVQDVLHQVNQSSVQVVLLFASVHAAHALFNYSISSRLSPKVWVAS 300
Query: 301 EAWLTSDLVMGLPGMAQMGTVLGFLQRGAQLHEFPQYVKTHLALATDPAFCSALGEREQG 360
EAWLTSDLVMGLPGMAQMGTVLGFLQRGAQLHEFPQYVKTHLALATDPAFCSALGEREQG
Sbjct: 301 EAWLTSDLVMGLPGMAQMGTVLGFLQRGAQLHEFPQYVKTHLALATDPAFCSALGEREQG 360
Query: 361 LEEDVVGQRCPQCDCITLQNVSAGLNHHQTFSVYAAVYSVAQALHNTLQCNASGCPAQDP 420
LEEDVVGQRCPQCDCITLQNVSAGLNHHQTFSVYAAVYSVAQALHNTLQCNASGCPAQDP
Sbjct: 361 LEEDVVGQRCPQCDCITLQNVSAGLNHHQTFSVYAAVYSVAQALHNTLQCNASGCPAQDP 420
Query: 421 VKPWQLLENMYNLTFHVGGLPLRFDSSGNVDMEYDLKLWVWQGSVPRLHDVGRFNGSLRT 480
VKPWQLLENMYNLTFHVGGLPLRFDSSGNVDMEYDLKLWVWQGSVPRLHDVGRFNGSLRT
Sbjct: 421 VKPWQLLENMYNLTFHVGGLPLRFDSSGNVDMEYDLKLWVWQGSVPRLHDVGRFNGSLRT 480
Query: 481 ERLKIRWHTSDNQKPVSRCSRQCQEGQVRRVKGFHSCCYDCVDCEAGSYRQNPDDIACTF 540
ERLKIRWHTSDNQKPVSRCSRQCQEGQVRRVKGFHSCCYDCVDCEAGSYRQNPDDIACTF
Sbjct: 481 ERLKIRWHTSDNQKPVSRCSRQCQEGQVRRVKGFHSCCYDCVDCEAGSYRQNPDDIACTF 540
Query: 541 CGQDEWSPERSTRCFRRRSRFLAWGEPAVLLLLLLLSLALGLVLAALGLFVHHRDSPLVQ 600
CGQDEWSPERSTRCFRRRSRFLAWGEPAVLLLLLLLSLALGLVLAALGLFVHHRDSPLVQ
Sbjct: 541 CGQDEWSPERSTRCFRRRSRFLAWGEPAVLLLLLLLSLALGLVLAALGLFVHHRDSPLVQ 600
Query: 601 ASGGPLACFGLVCLGLVCLSVLLFPGQPSPARCLAQQPLSHLPLTGCLSTLFLQAAEIFV 660
ASGGPLACFGLVCLGLVCLSVLLFPGQPSPARCLAQQPLSHLPLTGCLSTLFLQAAEIFV
Sbjct: 601 ASGGPLACFGLVCLGLVCLSVLLFPGQPSPARCLAQQPLSHLPLTGCLSTLFLQAAEIFV 660
Query: 661 ESELPLSWADRLSGCLRGPWAWLVVLLAMLVEVALCTWYLVAFPPEVVTDWHMLPTEALV 720
ESELPLSWADRLSGCLRGPWAWLVVLLAMLVEVALCTWYLVAFPPEVVTDWHMLPTEALV
Sbjct: 661 ESELPLSWADRLSGCLRGPWAWLVVLLAMLVEVALCTWYLVAFPPEVVTDWHMLPTEALV 720
Query: 721 HCRTRSWVSFGLAHATNATLAFLCFLGTFLVRSQPGRYNRARGLTFAMLAYFITWVSFVP 780
HCRTRSWVSFGLAHATNATLAFLCFLGTFLVRSQPGRYNRARGLTFAMLAYFITWVSFVP
Sbjct: 721 HCRTRSWVSFGLAHATNATLAFLCFLGTFLVRSQPGRYNRARGLTFAMLAYFITWVSFVP 780
Query: 781 LLANVQVVLRPAVQMGALLLCVLGILAAFHLPRCYLLMRQPGLNTPEFFLGGGPGDAQGQ 840
LLANVQVVLRPAVQMGALLLCVLGILAAFHLPRCYLLMRQPGLNTPEFFLGGGPGDAQGQ
Sbjct: 781 LLANVQVVLRPAVQMGALLLCVLGILAAFHLPRCYLLMRQPGLNTPEFFLGGGPGDAQGQ 840
Query: 841 NDGNTGNQGKHE 852
NDGNTGNQGKHE
Sbjct: 841 NDGNTGNQGKHE 852
>gi|29294615 sweet taste receptor T1r isoform b [Homo sapiens]
Length = 841
Score = 434 bits (1117), Expect = e-121
Identities = 274/821 (33%), Positives = 417/821 (50%), Gaps = 39/821 (4%)
Query: 26 SQQLRMKGDYVLGGLFPLGEAEEAGLRSRTRPSSPVCTR---FSSNGLLWALAMKMAVEE 82
S + GDY+L GLFPL L+ R RP +C R F+ +G AM++ VEE
Sbjct: 29 SPDFTLPGDYLLAGLFPL---HSGCLQVRHRPEVTLCDRSCSFNEHGYHLFQAMRLGVEE 85
Query: 83 INNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKAGSRDIAAYCNYTQYQPRVLAVI 142
INN + LLP + LGY L+D CS+ + +L L+ G I + Y P VLAVI
Sbjct: 86 INNSTALLPNITLGYQLYDVCSDSA-NVYATLRVLSLPGQHHIELQGDLLHYSPTVLAVI 144
Query: 143 GPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQLTAAAELLQ 202
GP S+ A T S FL+P +SY AS E LS + +PSF RT+P+D+ Q+ LLQ
Sbjct: 145 GPDSTNRAATTAALLSPFLVPMISYAASSETLSVKRQYPSFLRTIPNDKYQVETMVLLLQ 204
Query: 203 EFGWNWVAALGSDDEYGRQGLSIFSALAAARGICIAHEGLVPLP-RADDSRLGKVQDVLH 261
+FGW W++ +GS D+YG+ G+ A +GICIA + ++P + D R+ Q ++
Sbjct: 205 KFGWTWISLVGSSDDYGQLGVQALENQATGQGICIAFKDIMPFSAQVGDERM---QCLMR 261
Query: 262 QVNQSSVQVVLLFASVHAAHALFNYSISSRLSPKVWVASEAWLTSDLVMGLPGMAQMGTV 321
+ Q+ VV++F+S A F + + L+ KVWVASEAW S + G+PG+ ++G V
Sbjct: 262 HLAQAGATVVVVFSSRQLARVFFESVVLTNLTGKVWVASEAWALSRHITGVPGIQRIGMV 321
Query: 322 LGF-LQRGAQ--LHEFPQYVKTHLALATDP----AFCSALGEREQGLEEDVVGQRCPQCD 374
LG +Q+ A L F + A P ++CS+ Q C +C
Sbjct: 322 LGVAIQKRAVPGLKAFEEAYARADKKAPRPCHKGSWCSS-------------NQLCRECQ 368
Query: 375 CI---TLQNVSAGLNHHQTFSVYAAVYSVAQALHNTLQCNASGCPAQDPVKPWQLLENMY 431
T+ + A + ++ Y AVY+VA LH L C ASG ++ V PWQLLE ++
Sbjct: 369 AFMAHTMPKLKA-FSMSSAYNAYRAVYAVAHGLHQLLGC-ASGACSRGRVYPWQLLEQIH 426
Query: 432 NLTFHVGGLPLRFDSSGNVDMEYDLKLWVWQGSVPRLHDVGRFNGS---LRTERLKIRWH 488
+ F + + F+ + + Y++ W W G +G S L KI+WH
Sbjct: 427 KVHFLLHKDTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWH 486
Query: 489 TSDNQKPVSRCSRQCQEGQVRRVKGFHSCCYDCVDCEAGSYRQNPDDIACTFCGQDEWSP 548
DNQ P S CS C EG R V GFH CC++CV C AG++ D C CG++EW+P
Sbjct: 487 GKDNQVPKSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAP 546
Query: 549 ERSTRCFRRRSRFLAWGEPAVLLLLLLLSLALGLVLAALGLFVHHRDSPLVQASGGPLAC 608
E S CF R FLA E +LL +L L L+L GLF H D+P+V+++GG L
Sbjct: 547 EGSQTCFPRTVVFLALREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVRSAGGRLCF 606
Query: 609 FGLVCLGLVCLSVLLFPGQPSPARCLAQQPLSHLPLTGCLSTLFLQAAEIFVESELPLSW 668
L L S+ F G+P+ CL +Q L L T LS L +++ ++ + +
Sbjct: 607 LMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLIIIFKFSTKV 666
Query: 669 ADRLSGCLRGPWAWLVVLLAMLVEVALCTWYLVAFPPEVVTDWHMLPTEALVHCRTRSWV 728
++ A L V+++ ++ +C +LV + P ++ P ++ C + +
Sbjct: 667 PTFYHAWVQNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRFPHLVMLECTETNSL 726
Query: 729 SFGLAHATNATLAFLCFLGTFLVRSQPGRYNRARGLTFAMLAYFITWVSFVPLLANVQVV 788
F LA N L+ F ++L + P YN A+ +TF++L F++W++F +
Sbjct: 727 GFILAFLYNGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFFTTASVYDGK 786
Query: 789 LRPAVQMGALLLCVLGILAAFHLPRCYLLMRQPGLNTPEFF 829
PA M A L + + LP+CY+++ +P LN+ E F
Sbjct: 787 YLPAANMMAGLSSLSSGFGGYFLPKCYVILCRPDLNSTEHF 827
>gi|112807234 G protein-coupled receptor, family C, group 6, member
A [Homo sapiens]
Length = 926
Score = 392 bits (1008), Expect = e-109
Identities = 256/836 (30%), Positives = 420/836 (50%), Gaps = 57/836 (6%)
Query: 33 GDYVLGGLFPLGEAEEAGLRSRTRPSSPVCTRFSSNGLLWALAMKMAVEEINNKSDLLPG 92
G ++GGLF + E + S RP C F + L LAM ++E INN S LLPG
Sbjct: 34 GHIIIGGLFAIHEKMLSSEDSPRRPQIQECVGFEISVFLQTLAMIHSIEMINN-STLLPG 92
Query: 93 LRLGYDLFDTCSEPVVAMKPSLMFLAKAG-SRDIAAY-CNYTQYQPRVLAVIGPHSSELA 150
++LGY+++DTC+E VAM +L FL+K SR+ + C+Y+ Y PRV AVIG SE+
Sbjct: 93 VKLGYEIYDTCTEVTVAMAATLRFLSKFNCSRETVEFKCDYSSYMPRVKAVIGSGYSEIT 152
Query: 151 MVTGKFFSFFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQLTAAAELLQEFGWNWVA 210
M + + LMPQV Y ++ E+LS + FPSF RTVPSD Q+ A A L+Q+ GWNW+
Sbjct: 153 MAVSRMLNLQLMPQVGYESTAEILSDKIRFPSFLRTVPSDFHQIKAMAHLIQKSGWNWIG 212
Query: 211 ALGSDDEYGRQGLSIFSALAAARGICIAHEGLVPLPRADDSRLGKVQDVLHQ-VNQSSVQ 269
+ +DD+YGR L+ F A A +CIA + ++P +D++ ++ L + + ++ V
Sbjct: 213 IITTDDDYGRLALNTFIIQAEANNVCIAFKEVLPAFLSDNTIEVRINRTLKKIILEAQVN 272
Query: 270 VVLLFASVHAAHALFNYSISSRLSPKVWVASEAWLTSDLVMGLPGMAQMGTVLGFLQRGA 329
V+++F LFN +I ++ K+W+AS+ W T+ + +P + ++G V+GF R
Sbjct: 273 VIVVFLRQFHVFDLFNKAIEMNIN-KMWIASDNWSTATKITTIPNVKKIGKVVGFAFRRG 331
Query: 330 QLHEFPQYVKTHLALATDPAFCSALGEREQGLEEDVVGQRCPQCDCI------------- 376
+ F +++ L +D L E L + CI
Sbjct: 332 NISSFHSFLQNLHLLPSDSH--KLLHEYAMHLSACAYVKDTDLSQCIFNHSQRTLAYKAN 389
Query: 377 -------TLQN------VSAGLNHHQTFSVYAAVYSVAQALHNTLQCNASGCPAQDPVKP 423
++N GL H +V+A Y++ C A C + +P
Sbjct: 390 KAIERNFVMRNDFLWDYAEPGLIHSIQLAVFALGYAIRDL------CQARDCQNPNAFQP 443
Query: 424 WQLLENMYNLTFHVGGLPLRFDSSGNVDMEYDLKLWV---WQGSVPRLHDVGRFNGSLRT 480
W+LL + N+TF G FD+ G+++ YD+ LW +V ++ + N
Sbjct: 444 WELLGVLKNVTFTDGWNSFHFDAHGDLNTGYDVVLWKEINGHMTVTKMAEYDLQNDVFII 503
Query: 481 ERLKIRWHTSDNQKPVSRCSRQCQEGQVRR-VKGFHSCCYDCVDCEAGSYRQNPDDIACT 539
+ + + ++ S+CS++C GQ+++ + H CCY+C +C Y D C
Sbjct: 504 PDQETKNEFRNLKQIQSKCSKECSPGQMKKTTRSQHICCYECQNCPENHYTNQTDMPHCL 563
Query: 540 FC-GQDEWSPERSTRCFRRRSRFLAWGEPAVLLLLLLLSLALGLVLAALGLFVHHRDSPL 598
C + W+P RST CF + +L W + +LLL+L L + VL +F + ++P+
Sbjct: 564 LCNNKTHWAPVRSTMCFEKEVEYLNWNDSLAILLLILSLLGIIFVLVVGIIFTRNLNTPV 623
Query: 599 VQASGGPLACFG-LVCLGLVCLSVLLFPGQPSPARCLAQQPLSHLPLTGCLSTLFLQAAE 657
V++SGG C+ L+C L S F G+P C +Q + + T C+S + ++ +
Sbjct: 624 VKSSGGLRVCYVILLCHFLNFASTSFFIGEPQDFTCKTRQTMFGVSFTLCISCILTKSLK 683
Query: 658 IFVESELPLSWADRLS---GCLRGPWAWLVVLLAMLVEVALCTWYLVAFPPEVVTDWHML 714
I L S+ +L CL P L++ ++V +CT +L+ P V + L
Sbjct: 684 IL----LAFSFDPKLQKFLKCLYRP--ILIIFTCTGIQVVICTLWLIFAAPTVEVN-VSL 736
Query: 715 PTEALVHCRTRSWVSFGLAHATNATLAFLCFLGTFLVRSQPGRYNRARGLTFAMLAYFIT 774
P ++ C S ++FG A LAF+CF+ F + + YN A+ +TF ML YFI
Sbjct: 737 PRVIILECEEGSILAFGTMLGYIAILAFICFI--FAFKGKYENYNEAKFITFGMLIYFIA 794
Query: 775 WVSFVPLLANVQVVLRPAVQMGALLLCVLGILAAFHLPRCYLLMRQPGLNTPEFFL 830
W++F+P+ A PAV++ +L+ GIL +P+CY+++ + +NT FL
Sbjct: 795 WITFIPIYATTFGKYVPAVEIIVILISNYGILYCTFIPKCYVIICKQEINTKSAFL 850
>gi|37577159 calcium-sensing receptor [Homo sapiens]
Length = 1078
Score = 391 bits (1005), Expect = e-108
Identities = 264/878 (30%), Positives = 421/878 (47%), Gaps = 77/878 (8%)
Query: 12 WALL----HPGTGAPLCLSQQLRMKGDYVLGGLFPLG---EAEEAGLRSRTRPSSPVCTR 64
W LL H P Q+ + KGD +LGGLFP+ A++ L+SR P S C R
Sbjct: 8 WVLLALTWHTSAYGP---DQRAQKKGDIILGGLFPIHFGVAAKDQDLKSR--PESVECIR 62
Query: 65 FSSNGLLWALAMKMAVEEINNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLA--KAGS 122
++ G W AM A+EEIN+ LLP L LGY +FDTC+ A++ +L F+A K S
Sbjct: 63 YNFRGFRWLQAMIFAIEEINSSPALLPNLTLGYRIFDTCNTVSKALEATLSFVAQNKIDS 122
Query: 123 RDIAAYCNYTQYQPRVLAVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETFPS 182
++ +CN +++ P +AV+G S ++ F +PQVSY +S LLS + F S
Sbjct: 123 LNLDEFCNCSEHIPSTIAVVGATGSGVSTAVANLLGLFYIPQVSYASSSRLLSNKNQFKS 182
Query: 183 FFRTVPSDRVQLTAAAELLQEFGWNWVAALGSDDEYGRQGLSIFSALAAARGICIAHEGL 242
F RT+P+D Q TA A++++ F WNWV + +DD+YGR G+ F A R ICI L
Sbjct: 183 FLRTIPNDEHQATAMADIIEYFRWNWVGTIAADDDYGRPGIEKFREEAEERDICIDFSEL 242
Query: 243 VPLPRADDSRLGKVQDVLHQVNQSSVQVVLLFASVHAAHALFNYSISSRLSPKVWVASEA 302
+ + S ++Q V+ + S+ +V+++F+S L + ++ K+W+ASEA
Sbjct: 243 I----SQYSDEEEIQHVVEVIQNSTAKVIVVFSSGPDLEPLIKEIVRRNITGKIWLASEA 298
Query: 303 WLTSDLVMGLPGMAQMGTVLGFLQRGAQLHEFPQYV-KTHLALATDPAFCSALGERE--- 358
W +S L+ +G +GF + Q+ F +++ K H + F E
Sbjct: 299 WASSSLIAMPQYFHVVGGTIGFALKAGQIPGFREFLKKVHPRKSVHNGFAKEFWEETFNC 358
Query: 359 ----------------QGLEEDVVGQRCPQCD------CITLQNVSA------GLNHHQ- 389
+G EE G R C +N+S+ H +
Sbjct: 359 HLQEGAKGPLPVDTFLRGHEES--GDRFSNSSTAFRPLCTGDENISSVETPYIDYTHLRI 416
Query: 390 TFSVYAAVYSVAQALHNTLQC-------NASGCPAQDPVKPWQLLENMYNLTF-HVGGLP 441
+++VY AVYS+A AL + C C V+ WQ+L+++ +L F + G
Sbjct: 417 SYNVYLAVYSIAHALQDIYTCLPGRGLFTNGSCADIKKVEAWQVLKHLRHLNFTNNMGEQ 476
Query: 442 LRFDSSGNVDMEYDLKLW---VWQGSVPRLHDVGRFN-GSLRTERL-----KIRWHTSDN 492
+ FD G++ Y + W GS+ +VG +N + + ERL KI W
Sbjct: 477 VTFDECGDLVGNYSIINWHLSPEDGSIV-FKEVGYYNVYAKKGERLFINEEKILWSGFSR 535
Query: 493 QKPVSRCSRQCQEGQVRR-VKGFHSCCYDCVDCEAGSYRQNPDDIACTFCGQDEWSPERS 551
+ P S CSR C G + ++G +CC++CV+C G Y D AC C D WS E
Sbjct: 536 EVPFSNCSRDCLAGTRKGIIEGEPTCCFECVECPDGEYSDETDASACNKCPDDFWSNENH 595
Query: 552 TRCFRRRSRFLAWGEPAVLLLLLLLSLALGLVLAALGLFVHHRDSPLVQASGGPLACFGL 611
T C + FL+W EP + L L L + L LG+F+ R++P+V+A+ L+ L
Sbjct: 596 TSCIAKEIEFLSWTEPFGIALTLFAVLGIFLTAFVLGVFIKFRNTPIVKATNRELSYLLL 655
Query: 612 VCLGLVCLSVLLFPGQPSPARCLAQQPLSHLPLTGCLSTLFLQAAEIFV--ESELPLSWA 669
L S L F G+P C +QP + C+S + ++ + + E+++P S+
Sbjct: 656 FSLLCCFSSSLFFIGEPQDWTCRLRQPAFGISFVLCISCILVKTNRVLLVFEAKIPTSFH 715
Query: 670 DRLSGCLRGPWAWLVVLLAMLVEVALCTWYLVAFPPEVVTDWHMLPTEALVHCRTRSWVS 729
+ G +L+V L +++ +C +L PP + + + C S ++
Sbjct: 716 RKWWGL---NLQFLLVFLCTFMQIVICVIWLYTAPPSSYRNQELEDEIIFITCHEGSLMA 772
Query: 730 FGLAHATNATLAFLCFLGTFLVRSQPGRYNRARGLTFAMLAYFITWVSFVPLLANVQVVL 789
G LA +CF F R P +N A+ +TF+ML +FI W+SF+P A+
Sbjct: 773 LGFLIGYTCLLAAICFFFAFKSRKLPENFNEAKFITFSMLIFFIVWISFIPAYASTYGKF 832
Query: 790 RPAVQMGALLLCVLGILAAFHLPRCYLLMRQPGLNTPE 827
AV++ A+L G+LA + Y+++ +P NT E
Sbjct: 833 VSAVEVIAILAASFGLLACIFFNKIYIILFKPSRNTIE 870
>gi|112789566 taste receptor, type 1, member 2 [Homo sapiens]
Length = 839
Score = 379 bits (974), Expect = e-105
Identities = 254/835 (30%), Positives = 405/835 (48%), Gaps = 38/835 (4%)
Query: 11 LWALLHPGTGAPLCLSQQLRMKGDYVLGGLFPLGEAEEAGLRSRTRPSSPVCTRFSSNGL 70
LW L P + L GDY+LGGLF L A G+ P+C + +
Sbjct: 15 LWVLAEPAENSDFYLP------GDYLLGGLFSL-HANMKGIVHLNFLQVPMCKEYEVKVI 67
Query: 71 LWAL--AMKMAVEEINNKSDLLPGLRLGYDLFDTC--SEPVVAMKPSLMFLAKAGSRDIA 126
+ L AM+ AVEEINN S LLPG+ LGY++ D C S V +P L FLA + +
Sbjct: 68 GYNLMQAMRFAVEEINNDSSLLPGVLLGYEIVDVCYISNNV---QPVLYFLAHEDNL-LP 123
Query: 127 AYCNYTQYQPRVLAVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETFPSFFRT 186
+Y+ Y RV+AVIGP +SE M F S FL+PQ++Y A + L + FP+ RT
Sbjct: 124 IQEDYSNYISRVVAVIGPDNSESVMTVANFLSLFLLPQITYSAISDELRDKVRFPALLRT 183
Query: 187 VPSDRVQLTAAAELLQEFGWNWVAALGSDDEYGRQGLSIFSALAAARGICIAHEGLVPLP 246
PS + A +L+ F WNW+ L S D YGR + A R ICIA + +P
Sbjct: 184 TPSADHHIEAMVQLMLHFRWNWIIVLVSSDTYGRDNGQLLGERVARRDICIAFQETLPTL 243
Query: 247 RADDSRLG----KVQDVLHQVNQSSVQVVLLFASVHAAHALFNYSISSRLSPKVWVASEA 302
+ + + ++ ++ ++ QS+ +VV++F+ + FN + + VW+ASE+
Sbjct: 244 QPNQNMTSEERQRLVTIVDKLQQSTARVVVVFSPDLTLYHFFNEVLRQNFTGAVWIASES 303
Query: 303 WLTSDLVMGLPGMAQMGTVLGFLQRGAQLHEFPQYVKTHLALATDPAFCSALGEREQGLE 362
W ++ L + +GT LG + + F ++ + P L Q
Sbjct: 304 WAIDPVLHNLTELRHLGTFLGITIQSVPIPGFSEFREWGPQAGPPP-----LSRTSQSY- 357
Query: 363 EDVVGQRCPQCDCITLQ-NVSAGLNHHQ-TFSVYAAVYSVAQALHNTLQCNASGCPAQDP 420
Q C C TL N L+ + +SVY+AVY+VA ALH+ L C+ S C +
Sbjct: 358 --TCNQECDNCLNATLSFNTILRLSGERVVYSVYSAVYAVAHALHSLLGCDKSTC-TKRV 414
Query: 421 VKPWQLLENMYNLTFHVGGLPLRFDSSGNVDMEYDLKLWVWQGSVPRLHDVGRFNGSLRT 480
V PWQLLE ++ + F + + FD G+V + ++ W W S V + R
Sbjct: 415 VYPWQLLEEIWKVNFTLLDHQIFFDPQGDVALHLEIVQWQWDRSQNPFQSVASYYPLQRQ 474
Query: 481 ER--LKIRWHTSDNQKPVSRCSRQCQEGQVRRVKGFHSCCYDCVDCEAGSY-RQNPDDIA 537
+ I WHT +N P+S CS++CQ GQ ++ G H CC++C+DC G++ D+
Sbjct: 475 LKNIQDISWHTINNTIPMSMCSKRCQSGQKKKPVGIHVCCFECIDCLPGTFLNHTEDEYE 534
Query: 538 CTFCGQDEWSPERSTRCFRRRSRFLAWGEPAVLLLLLLLSLALGLVLAALGLFVHHRDSP 597
C C +EWS + T CF+R+ FL W E + + LL +L LA L +F H +P
Sbjct: 535 CQACPNNEWSYQSETSCFKRQLVFLEWHEAPTIAVALLAALGFLSTLAILVIFWRHFQTP 594
Query: 598 LVQASGGPLACFGLVCLGLVCLSVL-LFPGQPSPARCLAQQPLSHLPLTGCLSTLFLQAA 656
+V+++GGP+ CF ++ L LV V+ ++ G P + CL +Q L L T C+S + +++
Sbjct: 595 IVRSAGGPM-CFLMLTLLLVAYMVVPVYVGPPKVSTCLCRQALFPLCFTICISCIAVRSF 653
Query: 657 EIFVESELPLSWADRLSGCLR--GPWAWLVVLLAMLVEVALCTWYLVAFPPEVVTDWHML 714
+I ++ + S +R GP+ + + + + + + P TD
Sbjct: 654 QIVCAFKMASRFPRAYSYWVRYQGPYVSMAFITVLKMVIVVIGMLATGLSPTTRTDPDD- 712
Query: 715 PTEALVHCRTRSWVSFGLAHATNATLAFLCFLGTFLVRSQPGRYNRARGLTFAMLAYFIT 774
P +V C S + + L+ + F ++ + P YN A+ +T +M YF +
Sbjct: 713 PKITIVSCNPNYRNSLLFNTSLDLLLSVVGFSFAYMGKELPTNYNEAKFITLSMTFYFTS 772
Query: 775 WVSFVPLLANVQVVLRPAVQMGALLLCVLGILAAFHLPRCYLLMRQPGLNTPEFF 829
VS ++ VL V + +L +L I + P+CY+++ P NTP +F
Sbjct: 773 SVSLCTFMSAYSGVLVTIVDLLVTVLNLLAISLGYFGPKCYMILFYPERNTPAYF 827
>gi|66529100 glutamate receptor, metabotropic 2 isoform a precursor
[Homo sapiens]
Length = 872
Score = 233 bits (594), Expect = 6e-61
Identities = 235/858 (27%), Positives = 367/858 (42%), Gaps = 86/858 (10%)
Query: 9 LSLWALLHPGTGAPLCLSQQLRMKGDYVLGGLFPL----GEAEEAGLRSRTRPSSPVCTR 64
L LW + G + L ++GD VLGGLFP+ G AE+ G + R
Sbjct: 11 LLLWGAVAEGPAKKV-----LTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHR-------- 57
Query: 65 FSSNGLLWALAMKMAVEEINNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKA---- 120
G+ AM A++ IN LLPG+RLG + D+CS+ A++ +L F+ +
Sbjct: 58 ----GIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRG 113
Query: 121 --GSRDIA---AYCNYTQYQPRVLAVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLS 175
GSR I +Y + + VIG S++++ F +PQ+SY ++ LS
Sbjct: 114 ADGSRHICPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLS 173
Query: 176 ARETFPSFFRTVPSDRVQLTAAAELLQEFGWNWVAALGSDDEYGRQGLSIFSALAAARGI 235
+ + F RTVP D Q A AE+L+ F W +V+ + S+ +YG G+ F A AR I
Sbjct: 174 DKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNI 233
Query: 236 CIAHEGLVPLPRADDSRLGKVQDVLHQVNQSSVQVVLLFASVHAAHALFNYSISSRLSPK 295
C+A V + + G V+ +L + S +V +LF A L + S RL+
Sbjct: 234 CVATSEKVGRAMSRAAFEGVVRALL---QKPSARVAVLFTRSEDARELL--AASQRLNAS 288
Query: 296 -VWVASEAW-LTSDLVMGLPGMAQMGTVLGFLQRGAQLHEFPQYVKT--HLALATDPAFC 351
WVAS+ W +V G G A+ + + +F Y ++ + +P F
Sbjct: 289 FTWVASDGWGALESVVAGSEGAAEGAITIEL--ASYPISDFASYFQSLDPWNNSRNPWF- 345
Query: 352 SALGEREQGLEEDVVGQRCPQCDCITLQNVSAGLNHHQTFSVYAAVYSVAQALHNTLQCN 411
RE + R C +L+ V F V AVY++A ALHN +
Sbjct: 346 -----REFWEQRFRCSFRQRDCAAHSLRAVPFEQESKIMF-VVNAVYAMAHALHNMHRAL 399
Query: 412 ASG----CPAQDPVKPWQLLEN-MYNLTFHVGGLP------LRFDSSGNVDMEYDLKLWV 460
C A PV +L ++ + N+ F P +RFD G+ Y++ ++
Sbjct: 400 CPNTTRLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYL 459
Query: 461 WQGSVP-RLHDVGRFNGSLRTERLKIRWHT-SDNQKPVSRCSRQCQEGQVRRVKGFHSCC 518
GS R VG + L + I W + S P SRCS C + +V+ V+ CC
Sbjct: 460 RAGSGRYRYQKVGYWAEGLTLDTSLIPWASPSAGPLPASRCSEPCLQNEVKSVQPGEVCC 519
Query: 519 YDCVDCEAGSYRQNPDDIACTFCGQDEWSPERSTRCFRRRSRFLAWGEPAVLLLLLLLSL 578
+ C+ C+ YR D+ C CG W T CF ++ WG+ + + + L
Sbjct: 520 WLCIPCQPYEYRL--DEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACL 577
Query: 579 ALGLVLAALGLFVHHRDSPLVQASGGPLACFGLVCLGLVCLSVLLFPGQPSPARCLAQQP 638
L LG+FV H +P+V+ASG L L + L +F +PS A C ++
Sbjct: 578 GALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRL 637
Query: 639 LSHLPLTGCLSTLFLQA---AEIF------VESELPLSWADRLSGCLRGPWAWLVVLLAM 689
+ C S L + A IF + +S A +++ CL L++++A
Sbjct: 638 GLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQLLIVVAW 697
Query: 690 LVEVALCTWYLVA-FPPEVVTDWHMLPTEALVHCRTRSWVSFGLAHATNATLAFLCFLGT 748
LV A T A EVVT + C R G + A N L LC L
Sbjct: 698 LVVEAPGTGKETAPERREVVT----------LRCNHRDASMLG-SLAYNVLLIALCTLYA 746
Query: 749 FLVRSQPGRYNRARGLTFAMLAYFITWVSFVPLLANVQVVLRPAVQMGALLLCVLG--IL 806
F R P +N A+ + F M I W++F+P+ R + + + G +L
Sbjct: 747 FKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVL 806
Query: 807 AAFHLPRCYLLMRQPGLN 824
P+ ++++ QP N
Sbjct: 807 GCLFAPKLHIILFQPQKN 824
>gi|29294617 sweet taste receptor T1r isoform a [Homo sapiens]
Length = 480
Score = 232 bits (591), Expect = 1e-60
Identities = 149/414 (35%), Positives = 217/414 (52%), Gaps = 36/414 (8%)
Query: 26 SQQLRMKGDYVLGGLFPLGEAEEAGLRSRTRPSSPVCTR---FSSNGLLWALAMKMAVEE 82
S + GDY+L GLFPL L+ R RP +C R F+ +G AM++ VEE
Sbjct: 29 SPDFTLPGDYLLAGLFPL---HSGCLQVRHRPEVTLCDRSCSFNEHGYHLFQAMRLGVEE 85
Query: 83 INNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKAGSRDIAAYCNYTQYQPRVLAVI 142
INN + LLP + LGY L+D CS+ + +L L+ G I + Y P VLAVI
Sbjct: 86 INNSTALLPNITLGYQLYDVCSDSA-NVYATLRVLSLPGQHHIELQGDLLHYSPTVLAVI 144
Query: 143 GPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQLTAAAELLQ 202
GP S+ A T S FL+P +SY AS E LS + +PSF RT+P+D+ Q+ LLQ
Sbjct: 145 GPDSTNRAATTAALLSPFLVPMISYAASSETLSVKRQYPSFLRTIPNDKYQVETMVLLLQ 204
Query: 203 EFGWNWVAALGSDDEYGRQGLSIFSALAAARGICIAHEGLVPL-PRADDSRLGKVQDVLH 261
+FGW W++ +GS D+YG+ G+ A +GICIA + ++P + D R+ Q ++
Sbjct: 205 KFGWTWISLVGSSDDYGQLGVQALENQATGQGICIAFKDIMPFSAQVGDERM---QCLMR 261
Query: 262 QVNQSSVQVVLLFASVHAAHALFNYSISSRLSPKVWVASEAWLTSDLVMGLPGMAQMGTV 321
+ Q+ VV++F+S A F + + L+ KVWVASEAW S + G+PG+ ++G V
Sbjct: 262 HLAQAGATVVVVFSSRQLARVFFESVVLTNLTGKVWVASEAWALSRHITGVPGIQRIGMV 321
Query: 322 LGF-LQRGA--QLHEFPQYVKTHLALATDP----AFCSALGEREQGLEEDVVGQRCPQCD 374
LG +Q+ A L F + A P ++CS+ Q C +C
Sbjct: 322 LGVAIQKRAVPGLKAFEEAYARADKKAPRPCHKGSWCSS-------------NQLCRECQ 368
Query: 375 CI---TLQNVSAGLNHHQTFSVYAAVYSVAQALHNTLQCNASGCPAQDPVKPWQ 425
T+ + A + ++ Y AVY+VA LH L C ASG ++ V PWQ
Sbjct: 369 AFMAHTMPKLKA-FSMSSAYNAYRAVYAVAHGLHQLLGC-ASGACSRGRVYPWQ 420
>gi|110611176 glutamate receptor, metabotropic 6 precursor [Homo
sapiens]
Length = 877
Score = 213 bits (543), Expect = 5e-55
Identities = 209/846 (24%), Positives = 361/846 (42%), Gaps = 78/846 (9%)
Query: 29 LRMKGDYVLGGLFPLGEAEEAGLRSRTRPSSPVCTRFSSN-GLLWALAMKMAVEEINNKS 87
+R+ G LGGLFP+ AG C + G+ AM A++ +N
Sbjct: 33 VRLAGGLTLGGLFPVHARGAAGR---------ACGQLKKEQGVHRLEAMLYALDRVNADP 83
Query: 88 DLLPGLRLGYDLFDTCSEPVVAMKPSLMFL-----AKAGSRDIAAYC--NYTQYQP---- 136
+LLPG+RLG L DTCS A++ +L F+ + ++ C +P
Sbjct: 84 ELLPGVRLGARLLDTCSRDTYALEQALSFVQALIRGRGDGDEVGVRCPGGVPPLRPAPPE 143
Query: 137 RVLAVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQLTA 196
RV+AV+G +S ++++ F +PQ+SY ++ LS + F R VP D Q A
Sbjct: 144 RVVAVVGASASSVSIMVANVLRLFAIPQISYASTAPELSDSTRYDFFSRVVPPDSYQAQA 203
Query: 197 AAELLQEFGWNWVAALGSDDEYGRQGLSIFSALA-AARGICIAHEGLVPLPRADDSRLGK 255
++++ GWN+V+ L S+ YG G+ F ++ A G+CIA + +PR + + G+
Sbjct: 204 MVDIVRALGWNYVSTLASEGNYGESGVEAFVQISREAGGVCIAQS--IKIPR--EPKPGE 259
Query: 256 VQDVLHQVNQS-SVQVVLLFASVHAAHALFNYSISSRLSPK-VWVASEAW-LTSDLVMGL 312
V+ ++ ++ + + +++FA+ + + + L+ +WV S++W + ++ L
Sbjct: 260 FSKVIRRLMETPNARGIIIFANEDDIRRVLEAARQANLTGHFLWVGSDSWGAKTSPILSL 319
Query: 313 PGMAQMGTVLGFLQRGAQLHEFPQYVKTH----------LALATDPAFCSALGEREQGLE 362
+A +G + L + A + F QY T A + F L G +
Sbjct: 320 EDVA-VGAIT-ILPKRASIDGFDQYFMTRSLENNRRNIWFAEFWEENFNCKL--TSSGTQ 375
Query: 363 EDVVGQRCPQCDCITLQNVSAGLNHHQTFSVYAAVYSVAQALHNTLQCNASG----CPAQ 418
D ++C + I S + V AVY++A ALH+ Q G CPA
Sbjct: 376 SDDSTRKCTGEERIGRD--STYEQEGKVQFVIDAVYAIAHALHSMHQALCPGHTGLCPAM 433
Query: 419 DPVKPWQLLENMYNLTFH-VGGLPLRFDSSGNVDMEYDL-KLWVWQGSVPR--LHDVGRF 474
+P LL+ + + F+ G P+ F+ +G+ YD+ + GS VG++
Sbjct: 434 EPTDGRMLLQYIRAVRFNGSAGTPVMFNENGDAPGRYDIFQYQATNGSASSGGYQAVGQW 493
Query: 475 NGSLRTERLKIRWHTSDNQKPVSRCSRQCQEGQVRRVKGFHSCCYDCVDCEAGSYRQNPD 534
+LR + ++W ++ P S CS C G+ +++ CC+ C C+ YR D
Sbjct: 494 AETLRLDVEALQWSGDPHEVPSSLCSLPCGPGERKKMVKGVPCCWHCEACD--GYRFQVD 551
Query: 535 DIACTFCGQDEWSPERSTRCFRRRSRFLAWGEPAVLLLLLLLSLALGLVLAALGLFVHHR 594
+ C C D T C L+W P LLL L + + FV +
Sbjct: 552 EFTCEACPGDMRPTPNHTGCRPTPVVRLSWSSPWAAPPLLLAVLGIVATTTVVATFVRYN 611
Query: 595 DSPLVQASGGPLACFGLVCLGLVCLSVLLFPGQPSPARCLAQQPLSHLPLTGCLSTLFLQ 654
++P+V+ASG L+ L + L+ L +P A C A++ L T S L +
Sbjct: 612 NTPIVRASGRELSYVLLTGIFLIYAITFLMVAEPGAAVCAARRLFLGLGTTLSYSALLTK 671
Query: 655 A---AEIFVESELPLSWADRLSGCLRGPWAWLVVL--LAMLVEVALCTWYLVAFPPEVVT 709
IF + + ++ +S P + LV+ L L V + W L A PP V
Sbjct: 672 TNRIYRIFEQGKRSVTPPPFIS-----PTSQLVITFSLTSLQVVGMIAW-LGARPPHSVI 725
Query: 710 DWHMLPT------EALVHCRTRSWVSFGLAHATNATLAFLCFLGTFLVRSQPGRYNRARG 763
D+ T ++ C G + L C + R P +N A+
Sbjct: 726 DYEEQRTVDPEQARGVLKCDMSDLSLIGCL-GYSLLLMVTCTVYAIKARGVPETFNEAKP 784
Query: 764 LTFAMLAYFITWVSFVPLLANV-----QVVLRPAVQMGALLLCVLGILAAFHLPRCYLLM 818
+ F M I W++FVP+ ++ ++ +L L L ++P+ Y+++
Sbjct: 785 IGFTMYTTCIIWLAFVPIFFGTAQSAEKIYIQTTTLTVSLSLSASVSLGMLYVPKTYVIL 844
Query: 819 RQPGLN 824
P N
Sbjct: 845 FHPEQN 850
>gi|4504141 glutamate receptor, metabotropic 4 [Homo sapiens]
Length = 912
Score = 211 bits (536), Expect = 3e-54
Identities = 201/844 (23%), Positives = 352/844 (41%), Gaps = 76/844 (9%)
Query: 29 LRMKGDYVLGGLFPLGEAEEAGLRSRTRPSSPVCTRFSSNGLLWALAMKMAVEEINNKSD 88
+R+ GD LGGLFP+ R P G+ AM A++ INN D
Sbjct: 43 IRIDGDITLGGLFPV--------HGRGSEGKPCGELKKEKGIHRLEAMLFALDRINNDPD 94
Query: 89 LLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKAGSRDIAAYCNYTQYQP------RVLAVI 142
LLP + LG + DTCS A++ SL F+ +D + P RV+ VI
Sbjct: 95 LLPNITLGARILDTCSRDTHALEQSLTFVQALIEKDGTEVRCGSGGPPIITKPERVVGVI 154
Query: 143 GPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQLTAAAELLQ 202
G S ++++ F +PQ+SY ++ LS + F R VPSD Q A ++++
Sbjct: 155 GASGSSVSIMVANILRLFKIPQISYASTAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVR 214
Query: 203 EFGWNWVAALGSDDEYGRQGLSIFSALAAARG-ICIAHEGLVPLPRADDSRLGKVQDVLH 261
WN+V+ + S+ YG G+ F + G +CIA V +PR + + G+ ++
Sbjct: 215 ALKWNYVSTVASEGSYGESGVEAFIQKSREDGGVCIAQS--VKIPR--EPKAGEFDKIIR 270
Query: 262 QVNQSS-VQVVLLFASVHAAHALFNYSI-SSRLSPKVWVASEAWLTSDL-VMGLPGMAQM 318
++ ++S + V++FA+ + + +++ W+ S++W + V+ L +A+
Sbjct: 271 RLLETSNARAVIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKIAPVLHLEEVAEG 330
Query: 319 GTVLGFLQRGAQLHEFPQYVKTH----------LALATDPAFCSALGEREQGLEEDVVGQ 368
+ L + + F +Y + A + F L L++ +
Sbjct: 331 AVTI--LPKRMSVRGFDRYFSSRTLDNNRRNIWFAEFWEDNFHCKLSRH--ALKKGSHVK 386
Query: 369 RCPQCDCITLQNVSAGLNHHQTFSVYAAVYSVAQALHNTLQCNASG----CPAQDPVKPW 424
+C + I SA + V AVY++ ALH + G CP DPV
Sbjct: 387 KCTNRERIGQD--SAYEQEGKVQFVIDAVYAMGHALHAMHRDLCPGRVGLCPRMDPVDGT 444
Query: 425 QLLENMYNLTFH-VGGLPLRFDSSGNVDMEYDLKLWVWQGSVPRLHDVGRFNGSLRTERL 483
QLL+ + N+ F + G P+ F+ +G+ YD+ + + +G + L
Sbjct: 445 QLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQYQLRNDSAEYKVIGSWTDHLHLRIE 504
Query: 484 KIRWHTSDNQKPVSRCSRQCQEGQVRRVKGFHSCCYDCVDCEAGSYRQNPDDIACTFCGQ 543
++ W S Q P S CS CQ G+ ++ CC+ C C Y+ D C C
Sbjct: 505 RMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPCCWHCEPCT--GYQYQVDRYTCKTCPY 562
Query: 544 DEWSPERSTRCFRRRSRFLAWGEPAVLLLLLLLSLALGLVLAALGLFVHHRDSPLVQASG 603
D E T C L WG P +L L L + + L + FV + D+P+V+ASG
Sbjct: 563 DMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVGIAATLFVVITFVRYNDTPIVKASG 622
Query: 604 GPLACFGLVCLGLVCLSVLLFPGQPSPARCLAQQPLSHLPLT---GCLSTLFLQAAEIFV 660
L+ L + L + L +P C ++ L ++ L T + IF
Sbjct: 623 RELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLTKTNRIYRIFE 682
Query: 661 ESELPLSWADRLSGCLRGPWAWLVVLLAMLVEVALCTWYLVAFPPEVVTDWHMLPTEALV 720
+ + +S +S + + ++ L +L +C W++V P V D+ T
Sbjct: 683 QGKRSVSAPRFISPASQLAITFSLISLQLL---GICVWFVVD-PSHSVVDFQDQRTLDPR 738
Query: 721 HCRTRSWVSFGLAHATNATLAFLCFLGTFLV------------RSQPGRYNRARGLTFAM 768
R G+ + L+ +C LG ++ R P +N A+ + F M
Sbjct: 739 FAR-------GVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTM 791
Query: 769 LAYFITWVSFVPLLANV-----QVVLRPAVQMGALLLCVLGILAAFHLPRCYLLMRQPGL 823
I W++F+P+ ++ ++ ++ L L ++P+ Y+++ P
Sbjct: 792 YTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMPKVYIILFHPEQ 851
Query: 824 NTPE 827
N P+
Sbjct: 852 NVPK 855
>gi|46358417 glutamate receptor, metabotropic 3 precursor [Homo
sapiens]
Length = 879
Score = 209 bits (532), Expect = 9e-54
Identities = 210/857 (24%), Positives = 361/857 (42%), Gaps = 61/857 (7%)
Query: 25 LSQQLRMKGDYVLGGLFPLGE----AEEAGLRSRTRPSSPVCTRFSSNGLLWALAMKMAV 80
L ++++++GD VLGGLFP+ E EE G + R G+ AM A+
Sbjct: 29 LRREIKIEGDLVLGGLFPINEKGTGTEECGRINEDR------------GIQRLEAMLFAI 76
Query: 81 EEINNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKAGSR-DIAAY-CNYTQYQ--- 135
+EIN LLPG++LG + DTCS A++ SL F+ + ++ D A Y C Y
Sbjct: 77 DEINKDDYLLPGVKLGVHILDTCSRDTYALEQSLEFVRASLTKVDEAEYMCPDGSYAIQE 136
Query: 136 --PRVLA-VIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETFPSFFRTVPSDRV 192
P ++A VIG S +++ F +PQ+SY ++ LS + + F RTVP D
Sbjct: 137 NIPLLIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFY 196
Query: 193 QLTAAAELLQEFGWNWVAALGSDDEYGRQGLSIFSALAAARGICIAHEGLVPLPRADDSR 252
Q A AE+L+ F W +V+ + S+ +YG G+ F A R ICIA V S
Sbjct: 197 QAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLRNICIATAEKVGRSNIRKSY 256
Query: 253 LGKVQDVLHQVNQSSVQVVLLFASVHAAHALFNYSISSRLSPK-VWVASEAWLTSDLVMG 311
++++L + N +VV+LF + L + +SR + WVAS+ W + ++
Sbjct: 257 DSVIRELLQKPN---ARVVVLFMRSDDSRELI--AAASRANASFTWVASDGWGAQESIIK 311
Query: 312 LPGMAQMGTVLGFLQRGAQ-LHEFPQYVKTHLALAT--DPAFCSALGEREQGLEEDVVGQ 368
G + L+ +Q + +F +Y ++ +P F ++ Q ++
Sbjct: 312 GSEHVAYGAIT--LELASQPVRQFDRYFQSLNPYNNHRNPWFRDFWEQKFQCSLQNKRNH 369
Query: 369 RCPQCDCITLQNVSAGLNHHQTFSVYAAVYSVAQALH---NTLQCNASG-CPAQDPVKPW 424
R CD + S + V AVY++A ALH TL N + C A +
Sbjct: 370 R-RVCDKHLAIDSSNYEQESKIMFVVNAVYAMAHALHKMQRTLCPNTTKLCDAMKILDGK 428
Query: 425 QLLEN-MYNLTFHVGGLP-------LRFDSSGNVDMEYDLKLWVWQGSVPRLHDVGRFNG 476
+L ++ + + F P ++FD+ G+ Y++ + G VG +
Sbjct: 429 KLYKDYLLKINFTAPFNPNKDADSIVKFDTFGDGMGRYNVFNFQNVGGKYSYLKVGHWAE 488
Query: 477 SLRTERLKIRWHTSDNQKPVSRCSRQCQEGQVRRVKGFHSCCYDCVDCEAGSYRQNPDDI 536
+L + I W S N P S+CS C +++ ++ CC+ C+ CE Y D+
Sbjct: 489 TLSLDVNSIHW--SRNSVPTSQCSDPCAPNEMKNMQPGDVCCWICIPCE--PYEYLADEF 544
Query: 537 ACTFCGQDEWSPERSTRCFRRRSRFLAWGEPAVLLLLLLLSLALGLVLAALGLFVHHRDS 596
C CG +W T C+ ++ W + + + + L + +F+ H ++
Sbjct: 545 TCMDCGSGQWPTADLTGCYDLPEDYIRWEDAWAIGPVTIACLGFMCTCMVVTVFIKHNNT 604
Query: 597 PLVQASGGPLACFGLVCLGLVCLSVLLFPGQPSPARCLAQQPLSHLPLTGCLSTLFLQAA 656
PLV+ASG L L +GL F +PSP C ++ C S L +
Sbjct: 605 PLVKASGRELCYILLFGVGLSYCMTFFFIAKPSPVICALRRLGLGSSFAICYSALLTKTN 664
Query: 657 EIFVESELPLSWADRLSGCLRGPWAWLVVLLAMLVEVALCTWYLVAFPPEVVTDWHMLPT 716
I + + A R ++ + L ++ V + W ++ P
Sbjct: 665 CIARIFDGVKNGAQRPKFISPSSQVFICLGLILVQIVMVSVWLILEAPGTRRYTLAEKRE 724
Query: 717 EALVHCRTRSWVSFGLAHATNATLAFLCFLGTFLVRSQPGRYNRARGLTFAMLAYFITWV 776
++ C + S ++ + L LC + F R P +N A+ + F M I W+
Sbjct: 725 TVILKCNVKD-SSMLISLTYDVILVILCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWL 783
Query: 777 SFVPLLANVQVVLRPAVQMGALLLCVLG--ILAAFHLPRCYLLMRQPGLNTPEF------ 828
+F+P+ R + + + G +L P+ ++++ QP N
Sbjct: 784 AFLPIFYVTSSDYRVQTTTMCISVSLSGFVVLGCLFAPKVHIILFQPQKNVVTHRLHLNR 843
Query: 829 FLGGGPGDAQGQNDGNT 845
F G G Q+ +T
Sbjct: 844 FSVSGTGTTYSQSSAST 860
>gi|32528268 glutamate receptor, metabotropic 7 isoform b precursor
[Homo sapiens]
Length = 922
Score = 209 bits (531), Expect = 1e-53
Identities = 207/872 (23%), Positives = 371/872 (42%), Gaps = 89/872 (10%)
Query: 6 VLGLSLWALLHPGTGAPLCLSQQLRMKGDYVLGGLFPLGEAEEAGLRSRTRPSSPVCTRF 65
VL + L AL G + +R++GD LGGLFP+ +G+ P
Sbjct: 20 VLEVLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAKGPSGV--------PCGDIK 71
Query: 66 SSNGLLWALAMKMAVEEINNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKAGSRDI 125
NG+ AM A+++IN+ +LLP + LG + DTCS A++ SL F+ +D
Sbjct: 72 RENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLTFVQALIQKDT 131
Query: 126 AAYCNYTQYQP-------RVLAVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARE 178
+ T +P +V+ VIG S ++++ F +PQ+SY ++ LS
Sbjct: 132 SDV-RCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDR 190
Query: 179 TFPSFFRTVPSDRVQLTAAAELLQEFGWNWVAALGSDDEYGRQGLSIFSALA-AARGICI 237
+ F R VP D Q A ++++ GWN+V+ L S+ YG +G+ F+ ++ A G+CI
Sbjct: 191 RYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLCI 250
Query: 238 AHEGLVPLPRADDSRLGKVQDVLHQV--NQSSVQVVLLFASVHAAHALFNYSISSRLSPK 295
A +P R D R ++ Q+ +S VV+ L + ++
Sbjct: 251 AQSVRIPQERKD--RTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAKRADQVGHF 308
Query: 296 VWVASEAWLT--------SDLVMG-LPGMAQMGTVLGF--------LQRGAQLHEFPQYV 338
+WV S++W + D+ G + + TV GF L+ + F +Y
Sbjct: 309 LWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRRNVWFAEYW 368
Query: 339 KTHLALATDPAFCSALGEREQGLEEDVVGQRCPQCDCITLQNVSAGLNHHQTFS---VYA 395
+ + + G +++ + GQ + + N+ Q V
Sbjct: 369 EENFNCK-----LTISGSKKEDTDRKCTGQ----------ERIGKDSNYEQEGKVQFVID 413
Query: 396 AVYSVAQALHN---TLQCNASG-CPAQDPVKPWQLLENMYNLTFH-VGGLPLRFDSSGNV 450
AVY++A ALH+ L + G CP + +LL+ + N+ F+ G P+ F+ +G+
Sbjct: 414 AVYAMAHALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDA 473
Query: 451 DMEYDL-KLWVWQGSVPRLHDVGRFNGSLRTERLKIRWHTSDNQKPVSRCSRQCQEGQVR 509
YD+ + S P +G++ L+ ++W + P S C+ C+ GQ +
Sbjct: 474 PGRYDIFQYQTTNTSNPGYRLIGQWTDELQLNIEDMQWGKGVREIPASVCTLPCKPGQRK 533
Query: 510 RVKGFHSCCYDCVDCEAGSYRQNPDDIACTFCGQDEWSPERSTRCFRRRSRFLAWGEPAV 569
+ + CC+ C C+ Y+ D++ C C D+ E T C L W P
Sbjct: 534 KTQKGTPCCWTCEPCD--GYQYQFDEMTCQHCPYDQRPNENRTGCQDIPIIKLEWHSPWA 591
Query: 570 LLLLLLLSLALGLVLAALGLFVHHRDSPLVQASGGPLACFGLVCLGLVCLSVLLFPGQPS 629
++ + L L + + + F+ + D+P+V+ASG L+ L + L + L +P
Sbjct: 592 VIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPD 651
Query: 630 PARCLAQQPLSHLPLTGCLSTLFLQAAEIF--VESELPLSWADRLSGCLRGPWAWLVVLL 687
A C ++ L + + L + I+ E A RL P + L +
Sbjct: 652 VAVCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLI----SPTSQLAI-T 706
Query: 688 AMLVEVALC---TWYLVAFPPEVVTDWH----MLPTEA--LVHCR-TRSWVSFGLAHATN 737
+ L+ V L W+ V PP ++ D+ M P +A ++ C T + L + +
Sbjct: 707 SSLISVQLLGVFIWFGVD-PPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGY--S 763
Query: 738 ATLAFLCFLGTFLVRSQPGRYNRARGLTFAMLAYFITWVSFVPLLANV-----QVVLRPA 792
L C + R P +N A+ + F M I W++F+P+ ++ ++
Sbjct: 764 ILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTT 823
Query: 793 VQMGALLLCVLGILAAFHLPRCYLLMRQPGLN 824
++ L L ++P+ Y+++ P LN
Sbjct: 824 TLTISMNLSASVALGMLYMPKVYIIIFHPELN 855
>gi|4504147 glutamate receptor, metabotropic 7 isoform a precursor
[Homo sapiens]
Length = 915
Score = 209 bits (531), Expect = 1e-53
Identities = 207/872 (23%), Positives = 371/872 (42%), Gaps = 89/872 (10%)
Query: 6 VLGLSLWALLHPGTGAPLCLSQQLRMKGDYVLGGLFPLGEAEEAGLRSRTRPSSPVCTRF 65
VL + L AL G + +R++GD LGGLFP+ +G+ P
Sbjct: 20 VLEVLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAKGPSGV--------PCGDIK 71
Query: 66 SSNGLLWALAMKMAVEEINNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKAGSRDI 125
NG+ AM A+++IN+ +LLP + LG + DTCS A++ SL F+ +D
Sbjct: 72 RENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSLTFVQALIQKDT 131
Query: 126 AAYCNYTQYQP-------RVLAVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARE 178
+ T +P +V+ VIG S ++++ F +PQ+SY ++ LS
Sbjct: 132 SDV-RCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDR 190
Query: 179 TFPSFFRTVPSDRVQLTAAAELLQEFGWNWVAALGSDDEYGRQGLSIFSALA-AARGICI 237
+ F R VP D Q A ++++ GWN+V+ L S+ YG +G+ F+ ++ A G+CI
Sbjct: 191 RYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLCI 250
Query: 238 AHEGLVPLPRADDSRLGKVQDVLHQV--NQSSVQVVLLFASVHAAHALFNYSISSRLSPK 295
A +P R D R ++ Q+ +S VV+ L + ++
Sbjct: 251 AQSVRIPQERKD--RTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAKRADQVGHF 308
Query: 296 VWVASEAWLT--------SDLVMG-LPGMAQMGTVLGF--------LQRGAQLHEFPQYV 338
+WV S++W + D+ G + + TV GF L+ + F +Y
Sbjct: 309 LWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRRNVWFAEYW 368
Query: 339 KTHLALATDPAFCSALGEREQGLEEDVVGQRCPQCDCITLQNVSAGLNHHQTFS---VYA 395
+ + + G +++ + GQ + + N+ Q V
Sbjct: 369 EENFNCK-----LTISGSKKEDTDRKCTGQ----------ERIGKDSNYEQEGKVQFVID 413
Query: 396 AVYSVAQALHN---TLQCNASG-CPAQDPVKPWQLLENMYNLTFH-VGGLPLRFDSSGNV 450
AVY++A ALH+ L + G CP + +LL+ + N+ F+ G P+ F+ +G+
Sbjct: 414 AVYAMAHALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDA 473
Query: 451 DMEYDL-KLWVWQGSVPRLHDVGRFNGSLRTERLKIRWHTSDNQKPVSRCSRQCQEGQVR 509
YD+ + S P +G++ L+ ++W + P S C+ C+ GQ +
Sbjct: 474 PGRYDIFQYQTTNTSNPGYRLIGQWTDELQLNIEDMQWGKGVREIPASVCTLPCKPGQRK 533
Query: 510 RVKGFHSCCYDCVDCEAGSYRQNPDDIACTFCGQDEWSPERSTRCFRRRSRFLAWGEPAV 569
+ + CC+ C C+ Y+ D++ C C D+ E T C L W P
Sbjct: 534 KTQKGTPCCWTCEPCD--GYQYQFDEMTCQHCPYDQRPNENRTGCQDIPIIKLEWHSPWA 591
Query: 570 LLLLLLLSLALGLVLAALGLFVHHRDSPLVQASGGPLACFGLVCLGLVCLSVLLFPGQPS 629
++ + L L + + + F+ + D+P+V+ASG L+ L + L + L +P
Sbjct: 592 VIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPD 651
Query: 630 PARCLAQQPLSHLPLTGCLSTLFLQAAEIF--VESELPLSWADRLSGCLRGPWAWLVVLL 687
A C ++ L + + L + I+ E A RL P + L +
Sbjct: 652 VAVCSFRRVFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLI----SPTSQLAI-T 706
Query: 688 AMLVEVALC---TWYLVAFPPEVVTDWH----MLPTEA--LVHCR-TRSWVSFGLAHATN 737
+ L+ V L W+ V PP ++ D+ M P +A ++ C T + L + +
Sbjct: 707 SSLISVQLLGVFIWFGVD-PPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGY--S 763
Query: 738 ATLAFLCFLGTFLVRSQPGRYNRARGLTFAMLAYFITWVSFVPLLANV-----QVVLRPA 792
L C + R P +N A+ + F M I W++F+P+ ++ ++
Sbjct: 764 ILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTT 823
Query: 793 VQMGALLLCVLGILAAFHLPRCYLLMRQPGLN 824
++ L L ++P+ Y+++ P LN
Sbjct: 824 TLTISMNLSASVALGMLYMPKVYIIIFHPELN 855
>gi|29294619 sweet taste receptor T1r isoform c [Homo sapiens]
Length = 587
Score = 207 bits (526), Expect = 4e-53
Identities = 125/407 (30%), Positives = 200/407 (49%), Gaps = 3/407 (0%)
Query: 426 LLENMYNLTFHVGGLPLRFDSSGNVDMEYDLKLWVWQGSVPRLHDVGRFNGS---LRTER 482
LLE ++ + F + + F+ + + Y++ W W G +G S L
Sbjct: 167 LLEQIHKVHFLLHKDTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINE 226
Query: 483 LKIRWHTSDNQKPVSRCSRQCQEGQVRRVKGFHSCCYDCVDCEAGSYRQNPDDIACTFCG 542
KI+WH DNQ P S CS C EG R V GFH CC++CV C AG++ D C CG
Sbjct: 227 TKIQWHGKDNQVPKSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQPCG 286
Query: 543 QDEWSPERSTRCFRRRSRFLAWGEPAVLLLLLLLSLALGLVLAALGLFVHHRDSPLVQAS 602
++EW+PE S CF R FLA E +LL +L L L+L GLF H D+P+V+++
Sbjct: 287 KEEWAPEGSQTCFPRTVVFLALREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVRSA 346
Query: 603 GGPLACFGLVCLGLVCLSVLLFPGQPSPARCLAQQPLSHLPLTGCLSTLFLQAAEIFVES 662
GG L L L S+ F G+P+ CL +Q L L T LS L +++ ++ +
Sbjct: 347 GGRLCFLMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLIIIF 406
Query: 663 ELPLSWADRLSGCLRGPWAWLVVLLAMLVEVALCTWYLVAFPPEVVTDWHMLPTEALVHC 722
+ ++ A L V+++ ++ +C +LV + P ++ P ++ C
Sbjct: 407 KFSTKVPTFYHAWVQNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRFPHLVMLEC 466
Query: 723 RTRSWVSFGLAHATNATLAFLCFLGTFLVRSQPGRYNRARGLTFAMLAYFITWVSFVPLL 782
+ + F LA N L+ F ++L + P YN A+ +TF++L F++W++F
Sbjct: 467 TETNSLGFILAFLYNGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFFTTA 526
Query: 783 ANVQVVLRPAVQMGALLLCVLGILAAFHLPRCYLLMRQPGLNTPEFF 829
+ PA M A L + + LP+CY+++ +P LN+ E F
Sbjct: 527 SVYDGKYLPAANMMAGLSSLSSGFGGYFLPKCYVILCRPDLNSTEHF 573
Score = 90.5 bits (223), Expect = 6e-18
Identities = 56/143 (39%), Positives = 75/143 (52%), Gaps = 7/143 (4%)
Query: 26 SQQLRMKGDYVLGGLFPLGEAEEAGLRSRTRPSSPVCTR---FSSNGLLWALAMKMAVEE 82
S + GDY+L GLFPL L+ R RP +C R F+ +G AM++ VEE
Sbjct: 29 SPDFTLPGDYLLAGLFPL---HSGCLQVRHRPEVTLCDRSCSFNEHGYHLFQAMRLGVEE 85
Query: 83 INNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKAGSRDIAAYCNYTQYQPRVLAVI 142
INN + LLP + LGY L+D CS+ + +L L+ G I + Y P VLAVI
Sbjct: 86 INNSTALLPNITLGYQLYDVCSDS-ANVYATLRVLSLPGQHHIELQGDLLHYSPTVLAVI 144
Query: 143 GPHSSELAMVTGKFFSFFLMPQV 165
GP S+ A T S FL+P +
Sbjct: 145 GPDSTNRAATTAALLSPFLVPML 167
>gi|187960069 glutamate receptor, metabotropic 8 isoform b precursor
[Homo sapiens]
Length = 908
Score = 201 bits (511), Expect = 2e-51
Identities = 187/834 (22%), Positives = 351/834 (42%), Gaps = 57/834 (6%)
Query: 26 SQQLRMKGDYVLGGLFPLGEAEEAGLRSRTRPSSPVCTRFSSNGLLWALAMKMAVEEINN 85
+ +R+ GD +LGGLFP+ E G+ P G+ AM A+++IN
Sbjct: 37 AHSIRVDGDIILGGLFPVHAKGERGV--------PCGELKKEKGIHRLEAMLYAIDQINK 88
Query: 86 KSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKAGSRDIAAYCNYTQYQP------RVL 139
DLL + LG + DTCS A++ SL F+ +D + P ++
Sbjct: 89 DPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALIEKDASDVKCANGDPPIFTKPDKIS 148
Query: 140 AVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQLTAAAE 199
VIG +S ++++ F +PQ+SY ++ LS + F R VP D Q A +
Sbjct: 149 GVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVD 208
Query: 200 LLQEFGWNWVAALGSDDEYGRQGLSIFSALA-AARGICIAHEGLVPLPRADDSRLGKVQD 258
++ GWN+V+ L S+ YG G+ F+ ++ G+CIA +P + R G+ +
Sbjct: 209 IVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIP----REPRPGEFEK 264
Query: 259 VLHQVNQS-SVQVVLLFASVHAAHALFNYSISSRLSPK-VWVASEAWLTSDLVMGLPGMA 316
++ ++ ++ + + V++FA+ + + S +W+ S++W + +
Sbjct: 265 IIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEI 324
Query: 317 QMGTVLGFLQRGAQLHEFPQYVKTH-LALATDPAFCSALGEREQGLEEDVVGQRCPQC-D 374
G V L + A + F +Y ++ LA + + E G + G+R
Sbjct: 325 AEGAVT-ILPKRASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKK 383
Query: 375 CITLQNVSAGLNHHQTFS---VYAAVYSVAQALHNTLQCNASG----CPAQDPVKPWQLL 427
C L+ ++ ++ Q V AVYS+A ALHN + G CP + +LL
Sbjct: 384 CTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGKELL 443
Query: 428 ENMYNLTFH-VGGLPLRFDSSGNVDMEYDLKLWVWQGSVPRLHDVGRFNGSLRTERLKIR 486
+ + F+ G P+ F+ +G+ YD+ + +G + L + ++
Sbjct: 444 GYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQ 503
Query: 487 WHTSDNQKPVSRCSRQCQEGQVRRVKGFHSCCYDCVDCEAGSYRQNPDDIACTFCGQDEW 546
W ++ P S CS C+ G+ ++ CC+ C CE Y D+++C C D+
Sbjct: 504 WAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCE--GYNYQVDELSCELCPLDQR 561
Query: 547 SPERSTRCFRRRSRFLAWGEPAVLLLLLLLSLALGLVLAALGLFVHHRDSPLVQASGGPL 606
T C L W P ++ + + L + + FV + D+P+V+ASG L
Sbjct: 562 PNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGREL 621
Query: 607 ACFGLVCLGLVCLSVLLFPGQPSPARCLAQQPLSHLPLT---GCLSTLFLQAAEIFVESE 663
+ L + L L P C ++ L + L T + IF + +
Sbjct: 622 SYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGK 681
Query: 664 LPLSWADRLSGCLRGPWAWLVVLLAMLVE--VALCTWYLVAFPPEVVTDWHMLPT----- 716
++ +S P + LV+ +++ + + W++V PP ++ D+ T
Sbjct: 682 KSVTAPKFIS-----PASQLVITFSLISVQLLGVFVWFVVD-PPHIIIDYGEQRTLDPEK 735
Query: 717 -EALVHCRTRSWVSFGLAHATNATLAFLCFLGTFLVRSQPGRYNRARGLTFAMLAYFITW 775
++ C S +S + + L C + R P +N A+ + F M I W
Sbjct: 736 ARGVLKCDI-SDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIW 794
Query: 776 VSFVPLLANV-----QVVLRPAVQMGALLLCVLGILAAFHLPRCYLLMRQPGLN 824
++F+P+ ++ ++ ++ L L ++P+ Y+++ P N
Sbjct: 795 LAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQN 848
>gi|187960067 glutamate receptor, metabotropic 8 isoform a precursor
[Homo sapiens]
Length = 908
Score = 201 bits (511), Expect = 2e-51
Identities = 187/834 (22%), Positives = 351/834 (42%), Gaps = 57/834 (6%)
Query: 26 SQQLRMKGDYVLGGLFPLGEAEEAGLRSRTRPSSPVCTRFSSNGLLWALAMKMAVEEINN 85
+ +R+ GD +LGGLFP+ E G+ P G+ AM A+++IN
Sbjct: 37 AHSIRVDGDIILGGLFPVHAKGERGV--------PCGELKKEKGIHRLEAMLYAIDQINK 88
Query: 86 KSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKAGSRDIAAYCNYTQYQP------RVL 139
DLL + LG + DTCS A++ SL F+ +D + P ++
Sbjct: 89 DPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALIEKDASDVKCANGDPPIFTKPDKIS 148
Query: 140 AVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQLTAAAE 199
VIG +S ++++ F +PQ+SY ++ LS + F R VP D Q A +
Sbjct: 149 GVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVD 208
Query: 200 LLQEFGWNWVAALGSDDEYGRQGLSIFSALA-AARGICIAHEGLVPLPRADDSRLGKVQD 258
++ GWN+V+ L S+ YG G+ F+ ++ G+CIA +P + R G+ +
Sbjct: 209 IVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIP----REPRPGEFEK 264
Query: 259 VLHQVNQS-SVQVVLLFASVHAAHALFNYSISSRLSPK-VWVASEAWLTSDLVMGLPGMA 316
++ ++ ++ + + V++FA+ + + S +W+ S++W + +
Sbjct: 265 IIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEI 324
Query: 317 QMGTVLGFLQRGAQLHEFPQYVKTH-LALATDPAFCSALGEREQGLEEDVVGQRCPQC-D 374
G V L + A + F +Y ++ LA + + E G + G+R
Sbjct: 325 AEGAVT-ILPKRASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKK 383
Query: 375 CITLQNVSAGLNHHQTFS---VYAAVYSVAQALHNTLQCNASG----CPAQDPVKPWQLL 427
C L+ ++ ++ Q V AVYS+A ALHN + G CP + +LL
Sbjct: 384 CTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGKELL 443
Query: 428 ENMYNLTFH-VGGLPLRFDSSGNVDMEYDLKLWVWQGSVPRLHDVGRFNGSLRTERLKIR 486
+ + F+ G P+ F+ +G+ YD+ + +G + L + ++
Sbjct: 444 GYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQ 503
Query: 487 WHTSDNQKPVSRCSRQCQEGQVRRVKGFHSCCYDCVDCEAGSYRQNPDDIACTFCGQDEW 546
W ++ P S CS C+ G+ ++ CC+ C CE Y D+++C C D+
Sbjct: 504 WAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCE--GYNYQVDELSCELCPLDQR 561
Query: 547 SPERSTRCFRRRSRFLAWGEPAVLLLLLLLSLALGLVLAALGLFVHHRDSPLVQASGGPL 606
T C L W P ++ + + L + + FV + D+P+V+ASG L
Sbjct: 562 PNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGREL 621
Query: 607 ACFGLVCLGLVCLSVLLFPGQPSPARCLAQQPLSHLPLT---GCLSTLFLQAAEIFVESE 663
+ L + L L P C ++ L + L T + IF + +
Sbjct: 622 SYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGK 681
Query: 664 LPLSWADRLSGCLRGPWAWLVVLLAMLVE--VALCTWYLVAFPPEVVTDWHMLPT----- 716
++ +S P + LV+ +++ + + W++V PP ++ D+ T
Sbjct: 682 KSVTAPKFIS-----PASQLVITFSLISVQLLGVFVWFVVD-PPHIIIDYGEQRTLDPEK 735
Query: 717 -EALVHCRTRSWVSFGLAHATNATLAFLCFLGTFLVRSQPGRYNRARGLTFAMLAYFITW 775
++ C S +S + + L C + R P +N A+ + F M I W
Sbjct: 736 ARGVLKCDI-SDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIW 794
Query: 776 VSFVPLLANV-----QVVLRPAVQMGALLLCVLGILAAFHLPRCYLLMRQPGLN 824
++F+P+ ++ ++ ++ L L ++P+ Y+++ P N
Sbjct: 795 LAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQN 848
>gi|166999223 glutamate receptor, metabotropic 1 isoform beta
precursor [Homo sapiens]
Length = 906
Score = 194 bits (494), Expect = 2e-49
Identities = 216/844 (25%), Positives = 356/844 (42%), Gaps = 77/844 (9%)
Query: 30 RMKGDYVLGGLFPLGEAEEAGLRSRTRPSSPVCTRFSSNGLLWALAMKMAVEEINNKSDL 89
RM GD ++G LF + A + R + ++ G+ AM +++IN L
Sbjct: 40 RMDGDVIIGALFSVHHQPPAE-KVPERKCGEIREQY---GIQRVEAMFHTLDKINADPVL 95
Query: 90 LPGLRLGYDLFDTCSEPVVAMKPSLMFLAKA--GSRDIAAYCNYT----------QYQPR 137
LP + LG ++ D+C VA++ S+ F+ + RD N + +
Sbjct: 96 LPNITLGSEIRDSCWHSSVALEQSIEFIRDSLISIRDEKDGINRCLPDGQSLPPGRTKKP 155
Query: 138 VLAVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQLTAA 197
+ VIGP SS +A+ F +PQ++Y A+ LS + + F R VPSD +Q A
Sbjct: 156 IAGVIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAM 215
Query: 198 AELLQEFGWNWVAALGSDDEYGRQGLSIFSALAAARGICIAHEGLVPLPRAD---DSRLG 254
++++ + W +V+A+ ++ YG G+ F LAA G+CIAH + + D L
Sbjct: 216 LDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLR 275
Query: 255 KVQDVLHQVNQSSVQVVLLFASVHAAHALFNYSISSRLSPK---VWVASEAWLTSDLVMG 311
K+++ L + +VV+ F L S RL + S+ W D V+
Sbjct: 276 KLRERLPKA-----RVVVCFCEGMTVRGLL--SAMRRLGVVGEFSLIGSDGWADRDEVIE 328
Query: 312 LPGMAQMGTVLGFLQRGAQLHEFPQY-VKTHLALAT-DPAFCSALGEREQGLEEDVVGQR 369
+ G + LQ ++ F Y +K L T +P F R Q + +
Sbjct: 329 GYEVEANGGITIKLQ-SPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLEN 387
Query: 370 CPQCDCITLQNVSAGLNHHQTFS---VYAAVYSVAQALHNTLQCNASG----CPAQDPVK 422
P I N S N+ Q V A+Y++A L N G C A P+
Sbjct: 388 -PNFKRICTGNESLEENYVQDSKMGFVINAIYAMAHGLQNMHHALCPGHVGLCDAMKPID 446
Query: 423 PWQLLENMYNLTF-HVGGLPLRFDSSGNVDMEYDL-KLWVWQGSVPRLHDVGRFN-GSLR 479
+LL+ + +F V G + FD G+ YD+ L + + VG ++ G L
Sbjct: 447 GSKLLDFLIKSSFIGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLN 506
Query: 480 TERLKIRWHTSDNQKPVSRCSRQCQEGQVRRV-KGFHSCCYDCVDCEAGSYRQNPDDIAC 538
+ KI+ + S + V CS C +GQ++ + KG SCC+ C C+ Y Q D+ C
Sbjct: 507 IDDYKIQMNKSGVVRSV--CSEPCLKGQIKVIRKGEVSCCWICTACKENEYVQ--DEFTC 562
Query: 539 TFCGQDEWSPERSTRCFRRRSRFLAWGEPAVLLLLLLLSLALGLVLAALGLFVHHRDSPL 598
C W T C R+L W ++ + L + + L +FV +RD+P+
Sbjct: 563 KACDLGWWPNADLTGCEPIPVRYLEWSNIESIIAIAFSCLGILVTLFVTLIFVLYRDTPV 622
Query: 599 VQASGGPLACFGL--VCLGLVCLSVLLFPGQPSPARCLAQQPLSHLPLTGCLSTLFLQA- 655
V++S L L + LG VC L+ +P+ C Q+ L L C S L +
Sbjct: 623 VKSSSRELCYIILAGIFLGYVCPFTLI--AKPTTTSCYLQRLLVGLSSAMCYSALVTKTN 680
Query: 656 --AEIFVESELPLSWADRLSGCLRGP---WAWLVVLLAML---VEVALCTWYLVAFPPEV 707
A I S+ + C R P AW V++A + V++ L ++ PP
Sbjct: 681 RIARILAGSKKKI--------CTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMP 732
Query: 708 VTDWHMLPTEALVHCRTRSWVSFGLAHATNATLAFLCFLGTFLVRSQPGRYNRARGLTFA 767
+ + + L+ + V L + N L C F R+ P +N A+ + F
Sbjct: 733 ILSYPSIKEVYLICNTSNLGVVAPLGY--NGLLIMSCTYYAFKTRNVPANFNEAKYIAFT 790
Query: 768 MLAYFITWVSFVPLL--ANVQVVLRPAVQMGALLLCVLGILAAFHLPRCYLLMRQPGLNT 825
M I W++FVP+ +N +++ A+ L V L P+ Y+++ +P N
Sbjct: 791 MYTTCIIWLAFVPIYFGSNYKII----TTCFAVSLSVTVALGCMFTPKMYIIIAKPERNV 846
Query: 826 PEFF 829
F
Sbjct: 847 RSAF 850
>gi|166999098 glutamate receptor, metabotropic 1 isoform alpha
precursor [Homo sapiens]
Length = 1194
Score = 194 bits (494), Expect = 2e-49
Identities = 216/844 (25%), Positives = 356/844 (42%), Gaps = 77/844 (9%)
Query: 30 RMKGDYVLGGLFPLGEAEEAGLRSRTRPSSPVCTRFSSNGLLWALAMKMAVEEINNKSDL 89
RM GD ++G LF + A + R + ++ G+ AM +++IN L
Sbjct: 40 RMDGDVIIGALFSVHHQPPAE-KVPERKCGEIREQY---GIQRVEAMFHTLDKINADPVL 95
Query: 90 LPGLRLGYDLFDTCSEPVVAMKPSLMFLAKA--GSRDIAAYCNYT----------QYQPR 137
LP + LG ++ D+C VA++ S+ F+ + RD N + +
Sbjct: 96 LPNITLGSEIRDSCWHSSVALEQSIEFIRDSLISIRDEKDGINRCLPDGQSLPPGRTKKP 155
Query: 138 VLAVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQLTAA 197
+ VIGP SS +A+ F +PQ++Y A+ LS + + F R VPSD +Q A
Sbjct: 156 IAGVIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAM 215
Query: 198 AELLQEFGWNWVAALGSDDEYGRQGLSIFSALAAARGICIAHEGLVPLPRAD---DSRLG 254
++++ + W +V+A+ ++ YG G+ F LAA G+CIAH + + D L
Sbjct: 216 LDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLR 275
Query: 255 KVQDVLHQVNQSSVQVVLLFASVHAAHALFNYSISSRLSPK---VWVASEAWLTSDLVMG 311
K+++ L + +VV+ F L S RL + S+ W D V+
Sbjct: 276 KLRERLPKA-----RVVVCFCEGMTVRGLL--SAMRRLGVVGEFSLIGSDGWADRDEVIE 328
Query: 312 LPGMAQMGTVLGFLQRGAQLHEFPQY-VKTHLALAT-DPAFCSALGEREQGLEEDVVGQR 369
+ G + LQ ++ F Y +K L T +P F R Q + +
Sbjct: 329 GYEVEANGGITIKLQ-SPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLEN 387
Query: 370 CPQCDCITLQNVSAGLNHHQTFS---VYAAVYSVAQALHNTLQCNASG----CPAQDPVK 422
P I N S N+ Q V A+Y++A L N G C A P+
Sbjct: 388 -PNFKRICTGNESLEENYVQDSKMGFVINAIYAMAHGLQNMHHALCPGHVGLCDAMKPID 446
Query: 423 PWQLLENMYNLTF-HVGGLPLRFDSSGNVDMEYDL-KLWVWQGSVPRLHDVGRFN-GSLR 479
+LL+ + +F V G + FD G+ YD+ L + + VG ++ G L
Sbjct: 447 GSKLLDFLIKSSFIGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLN 506
Query: 480 TERLKIRWHTSDNQKPVSRCSRQCQEGQVRRV-KGFHSCCYDCVDCEAGSYRQNPDDIAC 538
+ KI+ + S + V CS C +GQ++ + KG SCC+ C C+ Y Q D+ C
Sbjct: 507 IDDYKIQMNKSGVVRSV--CSEPCLKGQIKVIRKGEVSCCWICTACKENEYVQ--DEFTC 562
Query: 539 TFCGQDEWSPERSTRCFRRRSRFLAWGEPAVLLLLLLLSLALGLVLAALGLFVHHRDSPL 598
C W T C R+L W ++ + L + + L +FV +RD+P+
Sbjct: 563 KACDLGWWPNADLTGCEPIPVRYLEWSNIESIIAIAFSCLGILVTLFVTLIFVLYRDTPV 622
Query: 599 VQASGGPLACFGL--VCLGLVCLSVLLFPGQPSPARCLAQQPLSHLPLTGCLSTLFLQA- 655
V++S L L + LG VC L+ +P+ C Q+ L L C S L +
Sbjct: 623 VKSSSRELCYIILAGIFLGYVCPFTLI--AKPTTTSCYLQRLLVGLSSAMCYSALVTKTN 680
Query: 656 --AEIFVESELPLSWADRLSGCLRGP---WAWLVVLLAML---VEVALCTWYLVAFPPEV 707
A I S+ + C R P AW V++A + V++ L ++ PP
Sbjct: 681 RIARILAGSKKKI--------CTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMP 732
Query: 708 VTDWHMLPTEALVHCRTRSWVSFGLAHATNATLAFLCFLGTFLVRSQPGRYNRARGLTFA 767
+ + + L+ + V L + N L C F R+ P +N A+ + F
Sbjct: 733 ILSYPSIKEVYLICNTSNLGVVAPLGY--NGLLIMSCTYYAFKTRNVPANFNEAKYIAFT 790
Query: 768 MLAYFITWVSFVPLL--ANVQVVLRPAVQMGALLLCVLGILAAFHLPRCYLLMRQPGLNT 825
M I W++FVP+ +N +++ A+ L V L P+ Y+++ +P N
Sbjct: 791 MYTTCIIWLAFVPIYFGSNYKII----TTCFAVSLSVTVALGCMFTPKMYIIIAKPERNV 846
Query: 826 PEFF 829
F
Sbjct: 847 RSAF 850
>gi|219842343 glutamate receptor, metabotropic 5 isoform a precursor
[Homo sapiens]
Length = 1212
Score = 126 bits (317), Expect = 7e-29
Identities = 116/454 (25%), Positives = 201/454 (44%), Gaps = 33/454 (7%)
Query: 393 VYAAVYSVAQALHNTLQCNASG----CPAQDPVKPWQLLENMYNLTFH-VGGLPLRFDSS 447
V A+YS+A LHN G C A P+ +LLE++ F V G + FD +
Sbjct: 400 VINAIYSMAYGLHNMQMSLCPGYAGLCDAMKPIDGRKLLESLMKTNFTGVSGDTILFDEN 459
Query: 448 GNVDMEYDLKLWVWQGSVPRLH-DVGRF-NGSLRTERLKIRWHTSDNQKPVSRCSRQCQE 505
G+ Y++ + G + +VG + NG L+ + ++ W N S CS C++
Sbjct: 460 GDSPGRYEIMNFKEMGKDYFDYINVGSWDNGELKMDDDEV-WSKKSNIIR-SVCSEPCEK 517
Query: 506 GQVRRV-KGFHSCCYDCVDCEAGSYRQNPDDIACTFCGQDEWSPERSTRCFRRRSRFLAW 564
GQ++ + KG SCC+ C C+ Y D+ C C W + T C ++L W
Sbjct: 518 GQIKVIRKGEVSCCWTCTPCKENEYVF--DEYTCKACQLGSWPTDDLTGCDLIPVQYLRW 575
Query: 565 GEPAVLLLLLLLSLALGLVLAALGLFVHHRDSPLVQASGGPLACFGL--VCLGLVCLSVL 622
G+P + ++ L L L +F+ +RD+P+V++S L L +CLG +C L
Sbjct: 576 GDPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCL 635
Query: 623 LFPGQPSPARCLAQQ---PLSHLPLTGCLSTLFLQAAEIFVESELPLSWADR--LSGCLR 677
+ +P C Q+ LS L T + A I S+ + +S C +
Sbjct: 636 I--AKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQ 693
Query: 678 GPWAWLVVLLAMLVEVALCTWYLVAFPPEVVTDWHMLPTEALVHCRTRSWVSFGLAHATN 737
A++++ + + + VAL + PP+++ D+ + L+ T V L + N
Sbjct: 694 LVIAFILICIQLGIIVAL----FIMEPPDIMHDYPSIREVYLICNTTNLGVVTPLGY--N 747
Query: 738 ATLAFLCFLGTFLVRSQPGRYNRARGLTFAMLAYFITWVSFVPLL--ANVQVVLRPAVQM 795
L C F R+ P +N A+ + F M I W++FVP+ +N +++
Sbjct: 748 GLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKII----TMC 803
Query: 796 GALLLCVLGILAAFHLPRCYLLMRQPGLNTPEFF 829
++ L L +P+ Y+++ +P N F
Sbjct: 804 FSVSLSATVALGCMFVPKVYIILAKPERNVRSAF 837
Score = 102 bits (255), Expect = 1e-21
Identities = 65/219 (29%), Positives = 108/219 (49%), Gaps = 15/219 (6%)
Query: 31 MKGDYVLGGLFPLGEAEEAGLRSRTRPSSPVCTRFSSNGLLWALAMKMAVEEINNKSDLL 90
M GD ++G LF + + R V ++ G+ AM +E IN+ LL
Sbjct: 31 MPGDIIIGALFSVHHQPTVD-KVHERKCGAVREQY---GIQRVEAMLHTLERINSDPTLL 86
Query: 91 PGLRLGYDLFDTCSEPVVAMKPSLMF----LAKAGSRDIAAYC------NYTQYQPRVLA 140
P + LG ++ D+C VA++ S+ F L + + C ++ +P ++
Sbjct: 87 PNITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKP-IVG 145
Query: 141 VIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQLTAAAEL 200
VIGP SS +A+ F +PQ++Y A+ LS + F F R VPSD Q A ++
Sbjct: 146 VIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDI 205
Query: 201 LQEFGWNWVAALGSDDEYGRQGLSIFSALAAARGICIAH 239
++ + W +V+A+ ++ YG G+ F ++A GICIAH
Sbjct: 206 VKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAH 244
>gi|4504143 glutamate receptor, metabotropic 5 isoform b precursor
[Homo sapiens]
Length = 1180
Score = 126 bits (317), Expect = 7e-29
Identities = 116/454 (25%), Positives = 201/454 (44%), Gaps = 33/454 (7%)
Query: 393 VYAAVYSVAQALHNTLQCNASG----CPAQDPVKPWQLLENMYNLTFH-VGGLPLRFDSS 447
V A+YS+A LHN G C A P+ +LLE++ F V G + FD +
Sbjct: 400 VINAIYSMAYGLHNMQMSLCPGYAGLCDAMKPIDGRKLLESLMKTNFTGVSGDTILFDEN 459
Query: 448 GNVDMEYDLKLWVWQGSVPRLH-DVGRF-NGSLRTERLKIRWHTSDNQKPVSRCSRQCQE 505
G+ Y++ + G + +VG + NG L+ + ++ W N S CS C++
Sbjct: 460 GDSPGRYEIMNFKEMGKDYFDYINVGSWDNGELKMDDDEV-WSKKSNIIR-SVCSEPCEK 517
Query: 506 GQVRRV-KGFHSCCYDCVDCEAGSYRQNPDDIACTFCGQDEWSPERSTRCFRRRSRFLAW 564
GQ++ + KG SCC+ C C+ Y D+ C C W + T C ++L W
Sbjct: 518 GQIKVIRKGEVSCCWTCTPCKENEYVF--DEYTCKACQLGSWPTDDLTGCDLIPVQYLRW 575
Query: 565 GEPAVLLLLLLLSLALGLVLAALGLFVHHRDSPLVQASGGPLACFGL--VCLGLVCLSVL 622
G+P + ++ L L L +F+ +RD+P+V++S L L +CLG +C L
Sbjct: 576 GDPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCL 635
Query: 623 LFPGQPSPARCLAQQ---PLSHLPLTGCLSTLFLQAAEIFVESELPLSWADR--LSGCLR 677
+ +P C Q+ LS L T + A I S+ + +S C +
Sbjct: 636 I--AKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQ 693
Query: 678 GPWAWLVVLLAMLVEVALCTWYLVAFPPEVVTDWHMLPTEALVHCRTRSWVSFGLAHATN 737
A++++ + + + VAL + PP+++ D+ + L+ T V L + N
Sbjct: 694 LVIAFILICIQLGIIVAL----FIMEPPDIMHDYPSIREVYLICNTTNLGVVTPLGY--N 747
Query: 738 ATLAFLCFLGTFLVRSQPGRYNRARGLTFAMLAYFITWVSFVPLL--ANVQVVLRPAVQM 795
L C F R+ P +N A+ + F M I W++FVP+ +N +++
Sbjct: 748 GLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKII----TMC 803
Query: 796 GALLLCVLGILAAFHLPRCYLLMRQPGLNTPEFF 829
++ L L +P+ Y+++ +P N F
Sbjct: 804 FSVSLSATVALGCMFVPKVYIILAKPERNVRSAF 837
Score = 102 bits (255), Expect = 1e-21
Identities = 65/219 (29%), Positives = 108/219 (49%), Gaps = 15/219 (6%)
Query: 31 MKGDYVLGGLFPLGEAEEAGLRSRTRPSSPVCTRFSSNGLLWALAMKMAVEEINNKSDLL 90
M GD ++G LF + + R V ++ G+ AM +E IN+ LL
Sbjct: 31 MPGDIIIGALFSVHHQPTVD-KVHERKCGAVREQY---GIQRVEAMLHTLERINSDPTLL 86
Query: 91 PGLRLGYDLFDTCSEPVVAMKPSLMF----LAKAGSRDIAAYC------NYTQYQPRVLA 140
P + LG ++ D+C VA++ S+ F L + + C ++ +P ++
Sbjct: 87 PNITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKP-IVG 145
Query: 141 VIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQLTAAAEL 200
VIGP SS +A+ F +PQ++Y A+ LS + F F R VPSD Q A ++
Sbjct: 146 VIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDI 205
Query: 201 LQEFGWNWVAALGSDDEYGRQGLSIFSALAAARGICIAH 239
++ + W +V+A+ ++ YG G+ F ++A GICIAH
Sbjct: 206 VKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAH 244
>gi|29294621 sweet taste receptor T1r isoform d [Homo sapiens]
Length = 324
Score = 90.5 bits (223), Expect = 6e-18
Identities = 56/143 (39%), Positives = 75/143 (52%), Gaps = 7/143 (4%)
Query: 26 SQQLRMKGDYVLGGLFPLGEAEEAGLRSRTRPSSPVCTR---FSSNGLLWALAMKMAVEE 82
S + GDY+L GLFPL L+ R RP +C R F+ +G AM++ VEE
Sbjct: 29 SPDFTLPGDYLLAGLFPL---HSGCLQVRHRPEVTLCDRSCSFNEHGYHLFQAMRLGVEE 85
Query: 83 INNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKAGSRDIAAYCNYTQYQPRVLAVI 142
INN + LLP + LGY L+D CS+ + +L L+ G I + Y P VLAVI
Sbjct: 86 INNSTALLPNITLGYQLYDVCSDS-ANVYATLRVLSLPGQHHIELQGDLLHYSPTVLAVI 144
Query: 143 GPHSSELAMVTGKFFSFFLMPQV 165
GP S+ A T S FL+P +
Sbjct: 145 GPDSTNRAATTAALLSPFLVPML 167
Score = 73.2 bits (178), Expect = 1e-12
Identities = 38/107 (35%), Positives = 54/107 (50%), Gaps = 3/107 (2%)
Query: 426 LLENMYNLTFHVGGLPLRFDSSGNVDMEYDLKLWVWQGSVPRLHDVGRFNGS---LRTER 482
LLE ++ + F + + F+ + + Y++ W W G +G S L
Sbjct: 167 LLEQIHKVHFLLHKDTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINE 226
Query: 483 LKIRWHTSDNQKPVSRCSRQCQEGQVRRVKGFHSCCYDCVDCEAGSY 529
KI+WH DNQ P S CS C EG R V GFH CC++CV C AG++
Sbjct: 227 TKIQWHGKDNQVPKSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTF 273
>gi|167000400 gamma-aminobutyric acid (GABA) B receptor 1 isoform c
precursor [Homo sapiens]
Length = 899
Score = 58.9 bits (141), Expect = 2e-08
Identities = 37/143 (25%), Positives = 67/143 (46%), Gaps = 16/143 (11%)
Query: 75 AMKMAVEEINNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKAGSRDIAAYCNYTQY 134
A++MA+E++N++ D+LP L D+ +P A K Y Y
Sbjct: 129 AVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATK----------------YLYELLY 172
Query: 135 QPRVLAVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQL 194
+ ++ P S ++ + + + + +SYG+S LS R+ FP+FFRT PS +
Sbjct: 173 NDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHN 232
Query: 195 TAAAELLQEFGWNWVAALGSDDE 217
+L +++GW +A + E
Sbjct: 233 PTRVKLFEKWGWKKIATIQQTTE 255
>gi|11497612 gamma-aminobutyric acid (GABA) B receptor 1 isoform b
precursor [Homo sapiens]
Length = 844
Score = 58.9 bits (141), Expect = 2e-08
Identities = 37/143 (25%), Positives = 67/143 (46%), Gaps = 16/143 (11%)
Query: 75 AMKMAVEEINNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKAGSRDIAAYCNYTQY 134
A++MA+E++N++ D+LP L D+ +P A K Y Y
Sbjct: 74 AVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATK----------------YLYELLY 117
Query: 135 QPRVLAVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQL 194
+ ++ P S ++ + + + + +SYG+S LS R+ FP+FFRT PS +
Sbjct: 118 NDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHN 177
Query: 195 TAAAELLQEFGWNWVAALGSDDE 217
+L +++GW +A + E
Sbjct: 178 PTRVKLFEKWGWKKIATIQQTTE 200
>gi|10835015 gamma-aminobutyric acid (GABA) B receptor 1 isoform a
precursor [Homo sapiens]
Length = 961
Score = 58.9 bits (141), Expect = 2e-08
Identities = 37/143 (25%), Positives = 67/143 (46%), Gaps = 16/143 (11%)
Query: 75 AMKMAVEEINNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKAGSRDIAAYCNYTQY 134
A++MA+E++N++ D+LP L D+ +P A K Y Y
Sbjct: 191 AVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATK----------------YLYELLY 234
Query: 135 QPRVLAVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQL 194
+ ++ P S ++ + + + + +SYG+S LS R+ FP+FFRT PS +
Sbjct: 235 NDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHN 294
Query: 195 TAAAELLQEFGWNWVAALGSDDE 217
+L +++GW +A + E
Sbjct: 295 PTRVKLFEKWGWKKIATIQQTTE 317
>gi|40255245 G protein-coupled receptor 51 [Homo sapiens]
Length = 941
Score = 56.2 bits (134), Expect = 1e-07
Identities = 39/141 (27%), Positives = 67/141 (47%), Gaps = 16/141 (11%)
Query: 75 AMKMAVEEINNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKAGSRDIAAYCNYTQY 134
A+++A+E+I N+S L P L L+DT + +K A+ + +Y
Sbjct: 80 AVELAIEQIRNESLLRPYF-LDLRLYDTECDNAKGLK---------------AFYDAIKY 123
Query: 135 QPRVLAVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQL 194
P L V G + + + + + Q+S+ A+ +L+ ++ +P FFRTVPSD
Sbjct: 124 GPNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKYPYFFRTVPSDNAVN 183
Query: 195 TAAAELLQEFGWNWVAALGSD 215
A +LL+ + W V L D
Sbjct: 184 PAILKLLKHYQWKRVGTLTQD 204
>gi|134152694 guanylate cyclase 2F [Homo sapiens]
Length = 1108
Score = 43.9 bits (102), Expect = 6e-04
Identities = 72/358 (20%), Positives = 140/358 (39%), Gaps = 64/358 (17%)
Query: 122 SRDIAAYCNYTQYQPRVLAVIGPHSSELAMVTGKFFS--FFLMPQVSYGASMELLSARET 179
SR ++++ ++ Q + P E A + G + F V+Y L + +
Sbjct: 107 SRALSSFISHHQMASGFIGPTNPGYCEAASLLGNSWDKGIFSWACVNYE-----LDNKIS 161
Query: 180 FPSFFRTVPSD-RVQLTAAAELLQEFGWNWVAALGSDDEYGRQGLSIFSALAAARGICIA 238
+P+F RT+PS RV +T +++ F W + SD++ + ++ + G+ +
Sbjct: 162 YPTFSRTLPSPIRVLVT----VMKYFQWAHAGVISSDEDIWVHTANRVASALRSHGLPV- 216
Query: 239 HEGLVPLPRADDSRLGKVQDVLHQVNQSSVQVVLLFASVHAAHALFN-----YSISSRLS 293
G+V D + K +HQ ++ + ++ + +++ + + +
Sbjct: 217 --GVVLTTGQDSQSMRKALQRIHQADRIRIIIMCMHSALIGGETQMHLLECAHDLKMTDG 274
Query: 294 PKVWVASEAWLTSDLVMGLPGMAQMGTVLGFLQRGAQLHEFPQYVKTHLALATDPAF--- 350
V+V +A L S + T L+ +L E V T + + F
Sbjct: 275 TYVFVPYDALLYS--------LPYKHTPYRVLRNNPKLREAYDAVLTITVESQEKTFYQA 326
Query: 351 ---CSALGEREQGLEEDVVGQRCPQCDCITLQNVSAGLNHHQTFSVYAAVYSVAQALHNT 407
+A GE + LE D V ++Y ++Y +AQA++N
Sbjct: 327 FTEAAARGEIPEKLEFDQVSPLFG--------------------TIYNSIYFIAQAMNNA 366
Query: 408 LQCNASGCPAQDPVKPWQLLENMYNLTFHVGGLPLRFDSSGNVDMEY---DLKLWVWQ 462
++ N A L+++ N+ FH +R DS+GN EY D L W+
Sbjct: 367 MKENGQAGAA-------SLVQHSRNMQFHGFNQLMRTDSNGNGISEYVILDTNLKEWE 417
>gi|11496971 NMDA receptor 1 isoform NR1-1 precursor [Homo sapiens]
Length = 885
Score = 42.7 bits (99), Expect = 0.001
Identities = 36/157 (22%), Positives = 62/157 (39%), Gaps = 8/157 (5%)
Query: 159 FFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQLTAAAELLQEFGWNWVAALGSDDEY 218
F+ +P + M + S + SF RTVP Q + E+++ + WN + L SDD
Sbjct: 113 FYRIPVLGLTTRMSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYSWNHIILLVSDDHE 172
Query: 219 GRQGLSIFSALAAARGICIAHEGLVPLPRADDSRLGKVQDVLHQVNQSSVQVVLLFASVH 278
GR L R E D V +L + + +V++L AS
Sbjct: 173 GRAAQKRLETLLEER------ESKAEKVLQFDPGTKNVTALLMEAKELEARVIILSASED 226
Query: 279 AAHALFNYSISSRL--SPKVWVASEAWLTSDLVMGLP 313
A ++ + + S VW+ E ++ + + P
Sbjct: 227 DAATVYRAAAMLNMTGSGYVWLVGEREISGNALRYAP 263
>gi|11038637 NMDA receptor 1 isoform NR1-3 precursor [Homo sapiens]
Length = 938
Score = 42.7 bits (99), Expect = 0.001
Identities = 36/157 (22%), Positives = 62/157 (39%), Gaps = 8/157 (5%)
Query: 159 FFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQLTAAAELLQEFGWNWVAALGSDDEY 218
F+ +P + M + S + SF RTVP Q + E+++ + WN + L SDD
Sbjct: 113 FYRIPVLGLTTRMSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYSWNHIILLVSDDHE 172
Query: 219 GRQGLSIFSALAAARGICIAHEGLVPLPRADDSRLGKVQDVLHQVNQSSVQVVLLFASVH 278
GR L R E D V +L + + +V++L AS
Sbjct: 173 GRAAQKRLETLLEER------ESKAEKVLQFDPGTKNVTALLMEAKELEARVIILSASED 226
Query: 279 AAHALFNYSISSRL--SPKVWVASEAWLTSDLVMGLP 313
A ++ + + S VW+ E ++ + + P
Sbjct: 227 DAATVYRAAAMLNMTGSGYVWLVGEREISGNALRYAP 263
>gi|11038635 NMDA receptor 1 isoform NR1-2 precursor [Homo sapiens]
Length = 901
Score = 42.7 bits (99), Expect = 0.001
Identities = 36/157 (22%), Positives = 62/157 (39%), Gaps = 8/157 (5%)
Query: 159 FFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQLTAAAELLQEFGWNWVAALGSDDEY 218
F+ +P + M + S + SF RTVP Q + E+++ + WN + L SDD
Sbjct: 113 FYRIPVLGLTTRMSIYSDKSIHLSFLRTVPPYSHQSSVWFEMMRVYSWNHIILLVSDDHE 172
Query: 219 GRQGLSIFSALAAARGICIAHEGLVPLPRADDSRLGKVQDVLHQVNQSSVQVVLLFASVH 278
GR L R E D V +L + + +V++L AS
Sbjct: 173 GRAAQKRLETLLEER------ESKAEKVLQFDPGTKNVTALLMEAKELEARVIILSASED 226
Query: 279 AAHALFNYSISSRL--SPKVWVASEAWLTSDLVMGLP 313
A ++ + + S VW+ E ++ + + P
Sbjct: 227 DAATVYRAAAMLNMTGSGYVWLVGEREISGNALRYAP 263
>gi|194248052 glutamate receptor, metabotropic 2 isoform b [Homo
sapiens]
Length = 254
Score = 40.4 bits (93), Expect = 0.007
Identities = 53/214 (24%), Positives = 86/214 (40%), Gaps = 23/214 (10%)
Query: 623 LFPGQPSPARCLAQQPLSHLPLTGCLSTLFLQA---AEIF------VESELPLSWADRLS 673
+F +PS A C ++ + C S L + A IF + +S A +++
Sbjct: 4 IFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVA 63
Query: 674 GCLRGPWAWLVVLLAMLVEVALCTWYLVAFPP-EVVTDWHMLPTEALVHCRTRSWVSFGL 732
CL L++++A LV A T A EVVT + C R G
Sbjct: 64 ICLALISGQLLIVVAWLVVEAPGTGKETAPERREVVT----------LRCNHRDASMLG- 112
Query: 733 AHATNATLAFLCFLGTFLVRSQPGRYNRARGLTFAMLAYFITWVSFVPLLANVQVVLRPA 792
+ A N L LC L F R P +N A+ + F M I W++F+P+ R
Sbjct: 113 SLAYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQ 172
Query: 793 VQMGALLLCVLG--ILAAFHLPRCYLLMRQPGLN 824
+ + + G +L P+ ++++ QP N
Sbjct: 173 TTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKN 206
>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor
[Homo sapiens]
Length = 1336
Score = 35.4 bits (80), Expect = 0.23
Identities = 38/151 (25%), Positives = 60/151 (39%), Gaps = 9/151 (5%)
Query: 167 YGASMELLSARETFPSFFRTVPSDRVQLTAAAELLQEFGWNWVAALGSDDEYGRQGLSIF 226
+G + +L+ +E +F + S QL E+L+E+ W A+ + R LS
Sbjct: 145 HGGAALVLTPKEKGSTFLQLGSSTEQQLQVIFEVLEEYDWTSFVAVTTRAPGHRAFLSYI 204
Query: 227 SALAAARGICIAHEGLVPL-PRADDSRLGKVQDVLHQVNQSSVQVVLLFASVHAAHALFN 285
L + H G + L P A ++ L Q+ S Q+ LLF + A +F
Sbjct: 205 EVLTDGSLVGWEHRGALTLDPGAGEAVLSA------QLRSVSAQIRLLFCAREEAEPVFR 258
Query: 286 YSISSRL--SPKVWVASEAWLTSDLVMGLPG 314
+ + L S VW L G PG
Sbjct: 259 AAEEAGLTGSGYVWFMVGPQLAGGGGSGAPG 289
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.138 0.443
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,671,694
Number of Sequences: 37866
Number of extensions: 1610449
Number of successful extensions: 4713
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 4532
Number of HSP's gapped (non-prelim): 83
length of query: 852
length of database: 18,247,518
effective HSP length: 111
effective length of query: 741
effective length of database: 14,044,392
effective search space: 10406894472
effective search space used: 10406894472
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.