Search of human proteins with 8923559

Search of human proteins with 8923559

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|8923559 3-oxoacyl-ACP synthase, mitochondrial isoform 1
precursor [Homo sapiens]
         (459 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|8923559 3-oxoacyl-ACP synthase, mitochondrial isoform 1 precu...   920   0.0  
gi|223972627 3-oxoacyl-ACP synthase, mitochondrial isoform 2 pre...   456   e-128
gi|41872631 fatty acid synthase [Homo sapiens]                        107   3e-23
gi|4557237 acetyl-Coenzyme A acetyltransferase 1 precursor [Homo...    35   0.14 
gi|167614485 acetyl-coenzyme A acyltransferase 2 [Homo sapiens]        35   0.19 
gi|4504327 mitochondrial trifunctional protein, beta subunit pre...    34   0.32 
gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens]                32   1.6  
gi|219842266 usherin isoform B [Homo sapiens]                          31   2.1  
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    30   3.5  
gi|40548420 collectin sub-family member 11 isoform b [Homo sapiens]    30   3.5  
gi|13128972 collectin sub-family member 11 isoform a [Homo sapiens]    30   3.5  
gi|31543392 peroxisome proliferator-activated receptor gamma, co...    29   7.8  

>gi|8923559 3-oxoacyl-ACP synthase, mitochondrial isoform 1
           precursor [Homo sapiens]
          Length = 459

 Score =  920 bits (2377), Expect = 0.0
 Identities = 459/459 (100%), Positives = 459/459 (100%)

Query: 1   MSNCLQNFLKITSTRLLCSRLCQQLRSKRKFFGTVPISRLHRRVVITGIGLVTPLGVGTH 60
           MSNCLQNFLKITSTRLLCSRLCQQLRSKRKFFGTVPISRLHRRVVITGIGLVTPLGVGTH
Sbjct: 1   MSNCLQNFLKITSTRLLCSRLCQQLRSKRKFFGTVPISRLHRRVVITGIGLVTPLGVGTH 60

Query: 61  LVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQFNEQNFVSKSDIKSMSSPTI 120
           LVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQFNEQNFVSKSDIKSMSSPTI
Sbjct: 61  LVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQFNEQNFVSKSDIKSMSSPTI 120

Query: 121 MAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSPFFV 180
           MAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSPFFV
Sbjct: 121 MAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSPFFV 180

Query: 181 PKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCI 240
           PKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCI
Sbjct: 181 PKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDSCI 240

Query: 241 SPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMGEGAAVLVLEEYEHAVQRRARIYA 300
           SPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMGEGAAVLVLEEYEHAVQRRARIYA
Sbjct: 241 SPLSLAGFSRARALSTNSDPKLACRPFHPKRDGFVMGEGAAVLVLEEYEHAVQRRARIYA 300

Query: 301 EVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAEN 360
           EVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAEN
Sbjct: 301 EVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAEN 360

Query: 361 KAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEF 420
           KAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEF
Sbjct: 361 KAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTLACYYQKLPPTLNLDCSEPEF 420

Query: 421 DLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIAGL 459
           DLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIAGL
Sbjct: 421 DLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIAGL 459


>gi|223972627 3-oxoacyl-ACP synthase, mitochondrial isoform 2
           precursor [Homo sapiens]
          Length = 376

 Score =  456 bits (1173), Expect = e-128
 Identities = 229/233 (98%), Positives = 230/233 (98%)

Query: 1   MSNCLQNFLKITSTRLLCSRLCQQLRSKRKFFGTVPISRLHRRVVITGIGLVTPLGVGTH 60
           MSNCLQNFLKITSTRLLCSRLCQQLRSKRKFFGTVPISRLHRRVVITGIGLVTPLGVGTH
Sbjct: 1   MSNCLQNFLKITSTRLLCSRLCQQLRSKRKFFGTVPISRLHRRVVITGIGLVTPLGVGTH 60

Query: 61  LVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQFNEQNFVSKSDIKSMSSPTI 120
           LVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQFNEQNFVSKSDIKSMSSPTI
Sbjct: 61  LVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGSDEGQFNEQNFVSKSDIKSMSSPTI 120

Query: 121 MAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSPFFV 180
           MAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSPFFV
Sbjct: 121 MAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMIPLEVVSETALNFQTKGYNKVSPFFV 180

Query: 181 PKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVA 233
           PKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDA  + A
Sbjct: 181 PKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAHAVGDSFRFIAHGDAGHITA 233



 Score =  311 bits (797), Expect = 8e-85
 Identities = 156/174 (89%), Positives = 158/174 (90%), Gaps = 4/174 (2%)

Query: 290 HAVQRRARIYAEVLG----YGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQPEEISYI 345
           HAV       A  +G    +   GDAGHITAPDPEGEGALRCMAAALKDAGVQPEEISYI
Sbjct: 203 HAVSTACTTGAHAVGDSFRFIAHGDAGHITAPDPEGEGALRCMAAALKDAGVQPEEISYI 262

Query: 346 NAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTLACYYQ 405
           NAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTLACYYQ
Sbjct: 263 NAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTLACYYQ 322

Query: 406 KLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIAGL 459
           KLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIAGL
Sbjct: 323 KLPPTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGLTNSFGFGGTNATLCIAGL 376


>gi|41872631 fatty acid synthase [Homo sapiens]
          Length = 2511

 Score =  107 bits (266), Expect = 3e-23
 Identities = 111/427 (25%), Positives = 177/427 (41%), Gaps = 40/427 (9%)

Query: 44  VVITGIGLVTPLGVGTHLVWDRLIGGESGIVSLVGEEYKSIPCSVAAYVPRGS----DEG 99
           VVI G+    P        WD LIGG    V +V ++ +     +   +PR S    D  
Sbjct: 4   VVIAGMSGKLPESENLQEFWDNLIGG----VDMVTDDDRRWKAGLYG-LPRRSGKLKDLS 58

Query: 100 QFNEQNF-VSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGM-GMIPL 157
           +F+   F V      +M     + +     A+ D G +P S      TGV +G+ G    
Sbjct: 59  RFDASFFGVHPKQAHTMDPQLRLLLEVTYEAIVDGGINPDSLRG-THTGVWVGVSGSETS 117

Query: 158 EVVS---ETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTTGAH 214
           E +S   ET + +   G  +            M A ++S  +  +GP+ A+ TAC++   
Sbjct: 118 EALSRDPETLVGYSMVGCQRA-----------MMANRLSFFFDFRGPSIALDTACSSSLM 166

Query: 215 AVGDSFRFIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNSDPKLACRPFHPKRDGF 274
           A+ ++++ I  G     + GG +  + P +   F R   LS    P+  C+ F    +G+
Sbjct: 167 ALQNAYQAIHSGQCPAAIVGGINVLLKPNTSVQFLRLGMLS----PEGTCKAFDTAGNGY 222

Query: 275 VMGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDA-GHITAPDPEGEGALRCMAAALK 333
              EG   ++L +   A     R+YA +L  G + D         P G+   + + +  +
Sbjct: 223 CRSEGVVAVLLTKKSLA----RRVYATILNAGTNTDGFKEQGVTFPSGDIQEQLIRSLYQ 278

Query: 334 DAGVQPEEISYINAHATSTPLGDAAE-NKAIKHLFKDHAYALAVSSTKGATGHLLGAAGA 392
            AGV PE   YI AH T T +GD  E N   + L       L + STK   GH   A+G 
Sbjct: 279 SAGVAPESFEYIEAHGTGTKVGDPQELNGITRALCATRQEPLLIGSTKSNMGHPEPASGL 338

Query: 393 VEAAFTTLACYYQKLPPTLNLDCSEPEFDL---NYVPLKAQEWKTEKRFIGLTNSFGFGG 449
              A   L+  +    P L+     PE        + +  Q        +G+ NSFGFGG
Sbjct: 339 AALAKVLLSLEHGLWAPNLHFHSPNPEIPALLDGRLQVVDQPLPVRGGNVGI-NSFGFGG 397

Query: 450 TNATLCI 456
           +N  + +
Sbjct: 398 SNVHIIL 404


>gi|4557237 acetyl-Coenzyme A acetyltransferase 1 precursor [Homo
           sapiens]
          Length = 427

 Score = 35.0 bits (79), Expect = 0.14
 Identities = 40/150 (26%), Positives = 61/150 (40%), Gaps = 28/150 (18%)

Query: 98  EGQFNEQNFVSKSDIKSMS--SPTIMAIGAAELAMKDSGWHPQSEADQVATGVAIGMGMI 155
           E ++ E+++VSK  +K +   S T   IG+    +      P ++   +A   AI    I
Sbjct: 25  EIRYVERSYVSKPTLKEVVIVSATRTPIGSF---LGSLSLLPATKLGSIAIQGAIEKAGI 81

Query: 156 PLEVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTACTT---- 211
           P E V E  +    +G                  GQ   R  + G    +ST CTT    
Sbjct: 82  PKEEVKEAYMGNVLQG----------------GEGQAPTRQAVLGAGLPISTPCTTINKV 125

Query: 212 ---GAHAVGDSFRFIAHGDADVMVAGGTDS 238
              G  A+  + + +  G  DVMVAGG +S
Sbjct: 126 CASGMKAIMMASQSLMCGHQDVMVAGGMES 155


>gi|167614485 acetyl-coenzyme A acyltransferase 2 [Homo sapiens]
          Length = 397

 Score = 34.7 bits (78), Expect = 0.19
 Identities = 30/130 (23%), Positives = 55/130 (42%), Gaps = 17/130 (13%)

Query: 270 KRDGFV-------MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGE 322
           K+DG V       + +GA  +++   +   +      A ++GY +SG       P   G 
Sbjct: 240 KKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGI 294

Query: 323 GALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGA 382
           G +  ++ ALK AG+  +++  +  +    P   A E      + K +    A+     A
Sbjct: 295 GPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAI-----A 349

Query: 383 TGHLLGAAGA 392
            GH LG +G+
Sbjct: 350 LGHPLGGSGS 359


>gi|4504327 mitochondrial trifunctional protein, beta subunit
           precursor [Homo sapiens]
          Length = 474

 Score = 33.9 bits (76), Expect = 0.32
 Identities = 16/39 (41%), Positives = 21/39 (53%)

Query: 199 KGPNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTD 237
           K P H V+ AC +   A+      IA G  DV+VAGG +
Sbjct: 128 KTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVE 166


>gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens]
          Length = 2769

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 11/33 (33%), Positives = 19/33 (57%)

Query: 409  PTLNLDCSEPEFDLNYVPLKAQEWKTEKRFIGL 441
            P  ++D  EP ++L +  +K QEW   K  +G+
Sbjct: 2490 PKPDMDAMEPSYELIHTQMKTQEWDNSKSILGV 2522


>gi|219842266 usherin isoform B [Homo sapiens]
          Length = 5202

 Score = 31.2 bits (69), Expect = 2.1
 Identities = 20/95 (21%), Positives = 41/95 (43%)

Query: 332  LKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGATGHLLGAAG 391
            +++  +   EI   + H T T +  A  ++ + HL     Y++ + +  G  G+L G   
Sbjct: 2749 IQNGDILSYEIHMPDPHITLTNVTSAVLSQKVTHLIPFTNYSVTIVACSGGNGYLGGCTE 2808

Query: 392  AVEAAFTTLACYYQKLPPTLNLDCSEPEFDLNYVP 426
            ++    TT     Q + P   +  SE    +++ P
Sbjct: 2809 SLPTYVTTHPTVPQNVGPLSVIPLSESYVVISWQP 2843


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 30.4 bits (67), Expect = 3.5
 Identities = 14/29 (48%), Positives = 18/29 (62%)

Query: 312 GHITAPDPEGEGALRCMAAALKDAGVQPE 340
           GH+T+  P+  G L+C A  L  AGVQ E
Sbjct: 399 GHVTSMQPKEPGPLQCEAKPLGKAGVQLE 427


>gi|40548420 collectin sub-family member 11 isoform b [Homo sapiens]
          Length = 268

 Score = 30.4 bits (67), Expect = 3.5
 Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 7/103 (6%)

Query: 306 GLSGDAGHITAPDPEGEGALRCMAAALKDA-GVQPEEISYINAHATSTPLGDA----AEN 360
           G  GD+G I  P P GE  L C  + L+ A G    ++S + +         A     E+
Sbjct: 89  GEKGDSGDIGPPGPNGEPGLPCECSQLRKAIGEMDNQVSQLTSELKFIKNAVAGVRETES 148

Query: 361 KAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTLACY 403
           K    + ++  YA A  S +G  G L  +    EAA   +A Y
Sbjct: 149 KIYLLVKEEKRYADAQLSCQGRGGTL--SMPKDEAANGLMAAY 189


>gi|13128972 collectin sub-family member 11 isoform a [Homo sapiens]
          Length = 271

 Score = 30.4 bits (67), Expect = 3.5
 Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 7/103 (6%)

Query: 306 GLSGDAGHITAPDPEGEGALRCMAAALKDA-GVQPEEISYINAHATSTPLGDA----AEN 360
           G  GD+G I  P P GE  L C  + L+ A G    ++S + +         A     E+
Sbjct: 92  GEKGDSGDIGPPGPNGEPGLPCECSQLRKAIGEMDNQVSQLTSELKFIKNAVAGVRETES 151

Query: 361 KAIKHLFKDHAYALAVSSTKGATGHLLGAAGAVEAAFTTLACY 403
           K    + ++  YA A  S +G  G L  +    EAA   +A Y
Sbjct: 152 KIYLLVKEEKRYADAQLSCQGRGGTL--SMPKDEAANGLMAAY 192


>gi|31543392 peroxisome proliferator-activated receptor gamma,
           coactivator 1 beta [Homo sapiens]
          Length = 1023

 Score = 29.3 bits (64), Expect = 7.8
 Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 2/61 (3%)

Query: 314 ITAPDPEGEGALRCMAAALKDAGVQPEEISYIN--AHATSTPLGDAAENKAIKHLFKDHA 371
           ++ P PEG        AA K     PE    ++   HAT+ P   A + +     F DH 
Sbjct: 634 LSLPSPEGLSLKATPGAAHKLPKKHPERSELLSHLRHATAQPASQAGQKRPFSCSFGDHD 693

Query: 372 Y 372
           Y
Sbjct: 694 Y 694


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,126,829
Number of Sequences: 37866
Number of extensions: 747987
Number of successful extensions: 1724
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1709
Number of HSP's gapped (non-prelim): 16
length of query: 459
length of database: 18,247,518
effective HSP length: 106
effective length of query: 353
effective length of database: 14,233,722
effective search space: 5024503866
effective search space used: 5024503866
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.