Guide to the Human Genome
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Search of human proteins with 14150108

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14150108 EF-hand calcium binding domain 2 isoform a [Homo
sapiens]
         (162 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14150108 EF-hand calcium binding domain 2 isoform a [Homo sap...   324   2e-89
gi|221316729 EF-hand calcium binding domain 2 isoform b [Homo sa...   249   7e-67
gi|58218968 calmodulin 3 [Homo sapiens]                                96   1e-20
gi|4502549 calmodulin 2 [Homo sapiens]                                 96   1e-20
gi|5901912 calmodulin 1 [Homo sapiens]                                 96   1e-20
gi|4885111 calmodulin-like 3 [Homo sapiens]                            96   2e-20
gi|4757974 centrin 1 [Homo sapiens]                                    80   8e-16
gi|4757902 caltractin [Homo sapiens]                                   79   1e-15
gi|4507617 fast skeletal muscle troponin C [Homo sapiens]              79   1e-15
gi|46397403 centrin 3 [Homo sapiens]                                   73   1e-13
gi|223278387 calmodulin-like 5 [Homo sapiens]                          71   5e-13
gi|50897266 calmodulin-like 6 [Homo sapiens]                           70   1e-12
gi|29568111 myosin regulatory light chain 9 isoform a [Homo sapi...    66   1e-11
gi|17986273 fast skeletal myosin alkali light chain 1 isoform 1f...    64   6e-11
gi|4507615 troponin C, slow [Homo sapiens]                             64   7e-11
gi|17986275 fast skeletal myosin alkali light chain 1 isoform 3f...    63   1e-10
gi|4505303 smooth muscle and non-muscle myosin alkali light chai...    62   2e-10
gi|222144326 myosin regulatory light chain MRCL2 isoform A [Homo...    60   8e-10
gi|94981553 slow cardiac myosin regulatory light chain 2 [Homo s...    60   8e-10
gi|222144328 myosin regulatory light chain MRCL2 isoform B [Homo...    60   8e-10
gi|222144324 myosin regulatory light chain MRCL2 isoform A [Homo...    60   8e-10
gi|15809016 myosin regulatory light chain MRCL2 isoform A [Homo ...    60   8e-10
gi|11067753 calcium binding protein 5 [Homo sapiens]                   60   1e-09
gi|5453740 myosin, light chain 12A, regulatory, non-sarcomeric [...    59   1e-09
gi|28372499 myosin light chain, phosphorylatable, fast skeletal ...    58   4e-09
gi|110611180 calcium binding protein 2 isoform 2 [Homo sapiens]        58   4e-09
gi|88999583 myosin, light chain 6, alkali, smooth muscle and non...    57   7e-09
gi|110611178 calcium binding protein 2 isoform 1 [Homo sapiens]        57   7e-09
gi|21624641 calcium binding protein 4 [Homo sapiens]                   56   2e-08
gi|169167243 PREDICTED: similar to myosin regulatory light chain...    55   3e-08

>gi|14150108 EF-hand calcium binding domain 2 isoform a [Homo
           sapiens]
          Length = 162

 Score =  324 bits (830), Expect = 2e-89
 Identities = 162/162 (100%), Positives = 162/162 (100%)

Query: 1   MADEKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIA 60
           MADEKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIA
Sbjct: 1   MADEKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIA 60

Query: 61  EVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKY 120
           EVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKY
Sbjct: 61  EVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKY 120

Query: 121 MTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYITMMVIDEN 162
           MTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYITMMVIDEN
Sbjct: 121 MTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYITMMVIDEN 162


>gi|221316729 EF-hand calcium binding domain 2 isoform b [Homo
           sapiens]
          Length = 133

 Score =  249 bits (636), Expect = 7e-67
 Identities = 124/124 (100%), Positives = 124/124 (100%)

Query: 1   MADEKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIA 60
           MADEKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIA
Sbjct: 1   MADEKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIA 60

Query: 61  EVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKY 120
           EVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKY
Sbjct: 61  EVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKY 120

Query: 121 MTEE 124
           MTEE
Sbjct: 121 MTEE 124


>gi|58218968 calmodulin 3 [Homo sapiens]
          Length = 149

 Score = 95.9 bits (237), Expect = 1e-20
 Identities = 58/157 (36%), Positives = 89/157 (56%), Gaps = 11/157 (7%)

Query: 1   MADEKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIA 60
           MAD+   E+I  AEF    KEAF +FD + + T+  +E+GT++RSLG  PTE EL D+I 
Sbjct: 1   MADQLTEEQI--AEF----KEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMIN 54

Query: 61  EVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKY 120
           EV + +  G I F +FL +M   + +       E+ +  AF V D    G+++  EL   
Sbjct: 55  EV-DADGNGTIDFPEFLTMMARKMKDTD----SEEEIREAFRVFDKDGNGYISAAELRHV 109

Query: 121 MTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYITMM 157
           MT  GE  + EE++EM+  A       +NY++++ MM
Sbjct: 110 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146


>gi|4502549 calmodulin 2 [Homo sapiens]
          Length = 149

 Score = 95.9 bits (237), Expect = 1e-20
 Identities = 58/157 (36%), Positives = 89/157 (56%), Gaps = 11/157 (7%)

Query: 1   MADEKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIA 60
           MAD+   E+I  AEF    KEAF +FD + + T+  +E+GT++RSLG  PTE EL D+I 
Sbjct: 1   MADQLTEEQI--AEF----KEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMIN 54

Query: 61  EVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKY 120
           EV + +  G I F +FL +M   + +       E+ +  AF V D    G+++  EL   
Sbjct: 55  EV-DADGNGTIDFPEFLTMMARKMKDTD----SEEEIREAFRVFDKDGNGYISAAELRHV 109

Query: 121 MTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYITMM 157
           MT  GE  + EE++EM+  A       +NY++++ MM
Sbjct: 110 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146


>gi|5901912 calmodulin 1 [Homo sapiens]
          Length = 149

 Score = 95.9 bits (237), Expect = 1e-20
 Identities = 58/157 (36%), Positives = 89/157 (56%), Gaps = 11/157 (7%)

Query: 1   MADEKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIA 60
           MAD+   E+I  AEF    KEAF +FD + + T+  +E+GT++RSLG  PTE EL D+I 
Sbjct: 1   MADQLTEEQI--AEF----KEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMIN 54

Query: 61  EVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKY 120
           EV + +  G I F +FL +M   + +       E+ +  AF V D    G+++  EL   
Sbjct: 55  EV-DADGNGTIDFPEFLTMMARKMKDTD----SEEEIREAFRVFDKDGNGYISAAELRHV 109

Query: 121 MTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYITMM 157
           MT  GE  + EE++EM+  A       +NY++++ MM
Sbjct: 110 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146


>gi|4885111 calmodulin-like 3 [Homo sapiens]
          Length = 149

 Score = 95.5 bits (236), Expect = 2e-20
 Identities = 56/158 (35%), Positives = 90/158 (56%), Gaps = 11/158 (6%)

Query: 1   MADEKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIA 60
           MAD+   E+  V EF    KEAF +FD + +  +  RE+GT++RSLG  PTE EL D+++
Sbjct: 1   MADQLTEEQ--VTEF----KEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMS 54

Query: 61  EVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKY 120
           E+ + +  G + F +FL +M   + +       E+ +  AF V D    GF++  EL   
Sbjct: 55  EI-DRDGNGTVDFPEFLGMMARKMKDTD----NEEEIREAFRVFDKDGNGFVSAAELRHV 109

Query: 121 MTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYITMMV 158
           MT  GE  S EE++EM+ AA       +NY++++ ++V
Sbjct: 110 MTRLGEKLSDEEVDEMIRAADTDGDGQVNYEEFVRVLV 147


>gi|4757974 centrin 1 [Homo sapiens]
          Length = 172

 Score = 80.1 bits (196), Expect = 8e-16
 Identities = 43/141 (30%), Positives = 83/141 (58%), Gaps = 5/141 (3%)

Query: 17  KKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKF 76
           ++++EAF++FD + + T+D +E+   +R+LG  P + E+  +I+EV + E TG I F  F
Sbjct: 31  QEVREAFDLFDVDGSGTIDAKELKVAMRALGFEPRKEEMKKMISEV-DREGTGKISFNDF 89

Query: 77  LPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEM 136
           L VMT+ + E+      ++ +L+AF + D  + G ++   L +   E GE  + EE++EM
Sbjct: 90  LAVMTQKMSEKD----TKEEILKAFRLFDDDETGKISFKNLKRVANELGENLTDEELQEM 145

Query: 137 LSAAIDPESNSINYKDYITMM 157
           +  A       +N ++++ +M
Sbjct: 146 IDEADRDGDGEVNEEEFLRIM 166


>gi|4757902 caltractin [Homo sapiens]
          Length = 172

 Score = 79.3 bits (194), Expect = 1e-15
 Identities = 43/147 (29%), Positives = 87/147 (59%), Gaps = 5/147 (3%)

Query: 11  IVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGY 70
           +  E  ++I+EAF++FD +   T+DV+E+   +R+LG  P + E+  +I+E+ ++E TG 
Sbjct: 25  LTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEI-DKEGTGK 83

Query: 71  IRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQ 130
           + F  FL VMT+ + E+      ++ +L+AF++ D  + G ++   L +   E GE  + 
Sbjct: 84  MNFGDFLTVMTQKMSEKD----TKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTD 139

Query: 131 EEMEEMLSAAIDPESNSINYKDYITMM 157
           EE++EM+  A       ++ ++++ +M
Sbjct: 140 EELQEMIDEADRDGDGEVSEQEFLRIM 166


>gi|4507617 fast skeletal muscle troponin C [Homo sapiens]
          Length = 160

 Score = 79.3 bits (194), Expect = 1e-15
 Identities = 47/149 (31%), Positives = 81/149 (54%), Gaps = 6/149 (4%)

Query: 9   EIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPT 68
           E ++AEF    K AF++FD +    + V+E+GT++R LG  PT+ EL  +I EV +E+ +
Sbjct: 14  EEMIAEF----KAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEV-DEDGS 68

Query: 69  GYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPF 128
           G I FE+FL +M   + E   +   E+ L   F + D    G++  +EL +     GE  
Sbjct: 69  GTIDFEEFLVMMVRQMKE-DAKGKSEEELAECFRIFDRNADGYIDPEELAEIFRASGEHV 127

Query: 129 SQEEMEEMLSAAIDPESNSINYKDYITMM 157
           + EE+E ++          I++ +++ MM
Sbjct: 128 TDEEIESLMKDGDKNNDGRIDFDEFLKMM 156



 Score = 31.6 bits (70), Expect = 0.31
 Identities = 15/59 (25%), Positives = 35/59 (59%)

Query: 100 AFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYITMMV 158
           AF++ D+   G ++  EL   M   G+  ++EE++ ++    +  S +I++++++ MMV
Sbjct: 23  AFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEVDEDGSGTIDFEEFLVMMV 81


>gi|46397403 centrin 3 [Homo sapiens]
          Length = 167

 Score = 72.8 bits (177), Expect = 1e-13
 Identities = 47/156 (30%), Positives = 82/156 (52%), Gaps = 6/156 (3%)

Query: 5   KDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEE 64
           K R E+   E  ++IK+AFE+FD + +  +D  E+   +R+LG    + ++  ++ + + 
Sbjct: 17  KKRRELS-EEQKQEIKDAFELFDTDKDEAIDYHELKVAMRALGFDVKKADVLKILKDYDR 75

Query: 65  EEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEE 124
           E  TG I FE F  V+T+ +LER     P + +L+AF++ D    G ++   L +   E 
Sbjct: 76  EA-TGKITFEDFNEVVTDWILERD----PHEEILKAFKLFDDDDSGKISLRNLRRVAREL 130

Query: 125 GEPFSQEEMEEMLSAAIDPESNSINYKDYITMMVID 160
           GE  S EE+  M+          IN +++I +M  D
Sbjct: 131 GENMSDEELRAMIEEFDKDGDGEINQEEFIAIMTGD 166


>gi|223278387 calmodulin-like 5 [Homo sapiens]
          Length = 146

 Score = 70.9 bits (172), Expect = 5e-13
 Identities = 44/147 (29%), Positives = 77/147 (52%), Gaps = 8/147 (5%)

Query: 11  IVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGY 70
           +  E   + K+AF   D + N T++ +E+G  +++ G   +E +L  LI+EV+ +   G 
Sbjct: 5   LTPEEEAQYKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDGD-GE 63

Query: 71  IRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQ 130
           I F++FL         +K R   ED+ + AF   D    G +T DEL + M   G+P  Q
Sbjct: 64  ISFQEFLTAA------KKARAGLEDLQV-AFRAFDQDGDGHITVDELRRAMAGLGQPLPQ 116

Query: 131 EEMEEMLSAAIDPESNSINYKDYITMM 157
           EE++ M+  A   +   +NY+++  M+
Sbjct: 117 EELDAMIREADVDQDGRVNYEEFARML 143


>gi|50897266 calmodulin-like 6 [Homo sapiens]
          Length = 181

 Score = 69.7 bits (169), Expect = 1e-12
 Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 4/152 (2%)

Query: 6   DREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEE 65
           D  E + AE  K+ K  FE+FD E N  V   E+  ++  LG  PT+ EL  +  +V+ +
Sbjct: 25  DMTERLSAEQIKEYKGVFEMFDEEGNGEVKTGELEWLMSLLGINPTKSELASMAKDVDRD 84

Query: 66  EPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEG 125
              G+   + FL +M    +  +     E  L  AF V D   +G++  + L   +   G
Sbjct: 85  NK-GFFNCDGFLALMG---VYHEKAQNQESELRAAFRVFDKEGKGYIDWNTLKYVLMNAG 140

Query: 126 EPFSQEEMEEMLSAAIDPESNSINYKDYITMM 157
           EP ++ E E+M+  A      +I+Y++++ MM
Sbjct: 141 EPLNEVEAEQMMKEADKDGDRTIDYEEFVAMM 172


>gi|29568111 myosin regulatory light chain 9 isoform a [Homo
           sapiens]
          Length = 172

 Score = 65.9 bits (159), Expect = 1e-11
 Identities = 41/141 (29%), Positives = 70/141 (49%), Gaps = 9/141 (6%)

Query: 17  KKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKF 76
           ++ KEAF + D   +  +D  ++  ++ SLG  PT+  L  +++E       G I F  F
Sbjct: 32  QEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDEYLEGMMSEAP-----GPINFTMF 86

Query: 77  LPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEM 136
           L +  E L        PEDV+  AF   D    GF+ +D L + +T  G+ F+ EE++EM
Sbjct: 87  LTMFGEKLNGTD----PEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRFTDEEVDEM 142

Query: 137 LSAAIDPESNSINYKDYITMM 157
              A   +  + NY ++  ++
Sbjct: 143 YREAPIDKKGNFNYVEFTRIL 163


>gi|17986273 fast skeletal myosin alkali light chain 1 isoform 1f
           [Homo sapiens]
          Length = 194

 Score = 63.9 bits (154), Expect = 6e-11
 Identities = 45/157 (28%), Positives = 77/157 (49%), Gaps = 8/157 (5%)

Query: 3   DEKDREEIIVAEFHKK----IKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDL 58
           +EK     I  EF K+     KEAF +FD   ++ + + ++G ++R+LG  PT  E+  +
Sbjct: 35  EEKIDLSAIKIEFSKEQQDEFKEAFLLFDRTGDSKITLSQVGDVLRALGTNPTNAEVRKV 94

Query: 59  IAEVEEEEPTG-YIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDEL 117
           +     EE     I FE+FLP+M + +   K +   ED  +    V D    G +   EL
Sbjct: 95  LGNPSNEELNAKKIEFEQFLPMM-QAISNNKDQATYED-FVEGLRVFDKEGNGTVMGAEL 152

Query: 118 IKYMTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYI 154
              +   GE   +EE+E +++   D  +  INY+ ++
Sbjct: 153 RHVLATLGEKMKEEEVEALMAGQED-SNGCINYEAFV 188


>gi|4507615 troponin C, slow [Homo sapiens]
          Length = 161

 Score = 63.5 bits (153), Expect = 7e-11
 Identities = 39/150 (26%), Positives = 77/150 (51%), Gaps = 3/150 (2%)

Query: 9   EIIVAEFHKKIKEAFEVFD-HESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEP 67
           E +  E   + K AF++F     +  +  +E+G ++R LG  PT  EL ++I EV+E+  
Sbjct: 10  EQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDG- 68

Query: 68  TGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEP 127
           +G + F++FL +M   + +   +   E+ L   F + D    G++  DEL   +   GE 
Sbjct: 69  SGTVDFDEFLVMMVRCMKDDS-KGKSEEELSDLFRMFDKNADGYIDLDELKIMLQATGET 127

Query: 128 FSQEEMEEMLSAAIDPESNSINYKDYITMM 157
            +++++EE++          I+Y +++  M
Sbjct: 128 ITEDDIEELMKDGDKNNDGRIDYDEFLEFM 157



 Score = 32.0 bits (71), Expect = 0.24
 Identities = 15/52 (28%), Positives = 31/52 (59%)

Query: 107 AKRGFLTKDELIKYMTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYITMMV 158
           A+ G ++  EL K M   G+  + EE++EM+    +  S ++++ +++ MMV
Sbjct: 31  AEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMV 82


>gi|17986275 fast skeletal myosin alkali light chain 1 isoform 3f
           [Homo sapiens]
          Length = 150

 Score = 63.2 bits (152), Expect = 1e-10
 Identities = 42/144 (29%), Positives = 73/144 (50%), Gaps = 8/144 (5%)

Query: 12  VAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTG-Y 70
           +AEF    KEAF +FD   ++ + + ++G ++R+LG  PT  E+  ++     EE     
Sbjct: 8   IAEF----KEAFLLFDRTGDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAKK 63

Query: 71  IRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQ 130
           I FE+FLP+M + +   K +   ED  +    V D    G +   EL   +   GE   +
Sbjct: 64  IEFEQFLPMM-QAISNNKDQATYED-FVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKE 121

Query: 131 EEMEEMLSAAIDPESNSINYKDYI 154
           EE+E +++   D  +  INY+ ++
Sbjct: 122 EEVEALMAGQED-SNGCINYEAFV 144


>gi|4505303 smooth muscle and non-muscle myosin alkali light chain
           6B [Homo sapiens]
          Length = 208

 Score = 62.4 bits (150), Expect = 2e-10
 Identities = 43/149 (28%), Positives = 75/149 (50%), Gaps = 8/149 (5%)

Query: 11  IVAEFHK----KIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEE 66
           +V EF+K    + KEAFE+FD   +  +   + G ++R+LG  PT  E+  ++   + +E
Sbjct: 57  VVIEFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDE 116

Query: 67  -PTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEG 125
             +  + FE FLP++  +   R      +   L  F V D    G +   EL   +T  G
Sbjct: 117 LKSRRVDFETFLPMLQAVAKNRGQGTYED--YLEGFRVFDKEGNGKVMGAELRHVLTTLG 174

Query: 126 EPFSQEEMEEMLSAAIDPESNSINYKDYI 154
           E  ++EE+E +L A  +  +  INY+ ++
Sbjct: 175 EKMTEEEVETVL-AGHEDSNGCINYEAFL 202


>gi|222144326 myosin regulatory light chain MRCL2 isoform A [Homo
           sapiens]
          Length = 172

 Score = 60.1 bits (144), Expect = 8e-10
 Identities = 39/141 (27%), Positives = 68/141 (48%), Gaps = 9/141 (6%)

Query: 17  KKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKF 76
           ++ KEAF + D   +  +D  ++  ++ SLG  PT+  L  ++      E  G I F  F
Sbjct: 32  QEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMM-----NEAPGPINFTMF 86

Query: 77  LPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEM 136
           L +  E L        PEDV+  AF   D    G + +D L + +T  G+ F+ EE++E+
Sbjct: 87  LTMFGEKLNGTD----PEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDEL 142

Query: 137 LSAAIDPESNSINYKDYITMM 157
              A   +  + NY ++  ++
Sbjct: 143 YREAPIDKKGNFNYIEFTRIL 163


>gi|94981553 slow cardiac myosin regulatory light chain 2 [Homo
           sapiens]
          Length = 166

 Score = 60.1 bits (144), Expect = 8e-10
 Identities = 41/145 (28%), Positives = 74/145 (51%), Gaps = 8/145 (5%)

Query: 17  KKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKF 76
           ++ KEAF + D   +  +D  ++     +LG    + E  D   E+ +E P G I F  F
Sbjct: 27  QEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEID---EMIKEAP-GPINFTVF 82

Query: 77  LPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEM 136
           L +  E L        PE+ +L AF+V D   +G L  D + + +T + E FS+EE+++M
Sbjct: 83  LTMFGEKLKGAD----PEETILNAFKVFDPEGKGVLKADYVREMLTTQAERFSKEEVDQM 138

Query: 137 LSAAIDPESNSINYKDYITMMVIDE 161
            +A     + +++YK+ + ++   E
Sbjct: 139 FAAFPPDVTGNLDYKNLVHIITHGE 163


>gi|222144328 myosin regulatory light chain MRCL2 isoform B [Homo
           sapiens]
          Length = 154

 Score = 60.1 bits (144), Expect = 8e-10
 Identities = 39/141 (27%), Positives = 68/141 (48%), Gaps = 9/141 (6%)

Query: 17  KKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKF 76
           ++ KEAF + D   +  +D  ++  ++ SLG  PT+  L  ++      E  G I F  F
Sbjct: 14  QEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMM-----NEAPGPINFTMF 68

Query: 77  LPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEM 136
           L +  E L        PEDV+  AF   D    G + +D L + +T  G+ F+ EE++E+
Sbjct: 69  LTMFGEKLNGTD----PEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDEL 124

Query: 137 LSAAIDPESNSINYKDYITMM 157
              A   +  + NY ++  ++
Sbjct: 125 YREAPIDKKGNFNYIEFTRIL 145


>gi|222144324 myosin regulatory light chain MRCL2 isoform A [Homo
           sapiens]
          Length = 172

 Score = 60.1 bits (144), Expect = 8e-10
 Identities = 39/141 (27%), Positives = 68/141 (48%), Gaps = 9/141 (6%)

Query: 17  KKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKF 76
           ++ KEAF + D   +  +D  ++  ++ SLG  PT+  L  ++      E  G I F  F
Sbjct: 32  QEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMM-----NEAPGPINFTMF 86

Query: 77  LPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEM 136
           L +  E L        PEDV+  AF   D    G + +D L + +T  G+ F+ EE++E+
Sbjct: 87  LTMFGEKLNGTD----PEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDEL 142

Query: 137 LSAAIDPESNSINYKDYITMM 157
              A   +  + NY ++  ++
Sbjct: 143 YREAPIDKKGNFNYIEFTRIL 163


>gi|15809016 myosin regulatory light chain MRCL2 isoform A [Homo
           sapiens]
          Length = 172

 Score = 60.1 bits (144), Expect = 8e-10
 Identities = 39/141 (27%), Positives = 68/141 (48%), Gaps = 9/141 (6%)

Query: 17  KKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKF 76
           ++ KEAF + D   +  +D  ++  ++ SLG  PT+  L  ++      E  G I F  F
Sbjct: 32  QEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMM-----NEAPGPINFTMF 86

Query: 77  LPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEM 136
           L +  E L        PEDV+  AF   D    G + +D L + +T  G+ F+ EE++E+
Sbjct: 87  LTMFGEKLNGTD----PEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDEL 142

Query: 137 LSAAIDPESNSINYKDYITMM 157
              A   +  + NY ++  ++
Sbjct: 143 YREAPIDKKGNFNYIEFTRIL 163


>gi|11067753 calcium binding protein 5 [Homo sapiens]
          Length = 173

 Score = 59.7 bits (143), Expect = 1e-09
 Identities = 41/155 (26%), Positives = 81/155 (52%), Gaps = 2/155 (1%)

Query: 4   EKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVE 63
           EK RE  +  +  ++++EAF  FD + +  +  +++G ++R++G  PTE EL +L  ++ 
Sbjct: 18  EKQRERPLGQDEIEELREAFLEFDKDRDGFISCKDLGNLMRTMGYMPTEMELIELGQQI- 76

Query: 64  EEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTE 123
                G + F+ F+ +MT  LL      I    +  AF+  D+   G +T  EL + M  
Sbjct: 77  RMNLGGRVDFDDFVELMTPKLLAETAGMIGVQEMRDAFKEFDTNGDGEITLVELQQAMQR 136

Query: 124 -EGEPFSQEEMEEMLSAAIDPESNSINYKDYITMM 157
             GE  +  E+ E++  A      ++++++++ MM
Sbjct: 137 LLGERLTPREISEVVREADVNGDGTVDFEEFVKMM 171


>gi|5453740 myosin, light chain 12A, regulatory, non-sarcomeric
           [Homo sapiens]
          Length = 171

 Score = 59.3 bits (142), Expect = 1e-09
 Identities = 39/141 (27%), Positives = 68/141 (48%), Gaps = 9/141 (6%)

Query: 17  KKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKF 76
           ++ KEAF + D   +  +D  ++  ++ SLG  PT+  L  ++      E  G I F  F
Sbjct: 31  QEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDEYLDAMM-----NEAPGPINFTMF 85

Query: 77  LPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEM 136
           L +  E L        PEDV+  AF   D    G + +D L + +T  G+ F+ EE++E+
Sbjct: 86  LTMFGEKLNGTD----PEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDEL 141

Query: 137 LSAAIDPESNSINYKDYITMM 157
              A   +  + NY ++  ++
Sbjct: 142 YREAPIDKKGNFNYIEFTRIL 162


>gi|28372499 myosin light chain, phosphorylatable, fast skeletal
           muscle [Homo sapiens]
          Length = 169

 Score = 57.8 bits (138), Expect = 4e-09
 Identities = 40/136 (29%), Positives = 68/136 (50%), Gaps = 8/136 (5%)

Query: 17  KKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKF 76
           ++ KEAF V D   +  +D  ++     ++G    + E  D + +    E +G I F  F
Sbjct: 28  QEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKNEELDAMMK----EASGPINFTVF 83

Query: 77  LPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEM 136
           L +  E L        PEDV+  AF+VLD   +G + K  L + +T + + FSQEE++ M
Sbjct: 84  LTMFGEKLKGAD----PEDVITGAFKVLDPEGKGTIKKKFLEELLTTQCDRFSQEEIKNM 139

Query: 137 LSAAIDPESNSINYKD 152
            +A       +++YK+
Sbjct: 140 WAAFPPDVGGNVDYKN 155


>gi|110611180 calcium binding protein 2 isoform 2 [Homo sapiens]
          Length = 163

 Score = 57.8 bits (138), Expect = 4e-09
 Identities = 45/154 (29%), Positives = 77/154 (50%), Gaps = 7/154 (4%)

Query: 5   KDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEE 64
           KDRE  +  E  ++++ AF+ FD + +  +  RE+G  +R+LG  PTE EL     E+ +
Sbjct: 14  KDRE--LRPEEIEELQVAFQEFDRDRDGYIGCRELGACMRTLGYMPTEMEL----IEISQ 67

Query: 65  EEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTE- 123
           +   G + FE F+ +M   LL      I    L  AF   D+   G ++  EL   +   
Sbjct: 68  QISGGKVDFEDFVELMGPKLLAETADMIGVRELRDAFREFDTNGDGRISVGELRAALKAL 127

Query: 124 EGEPFSQEEMEEMLSAAIDPESNSINYKDYITMM 157
            GE  SQ E++E+L          +++++++ MM
Sbjct: 128 LGERLSQREVDEILQDVDLNGDGLVDFEEFVRMM 161


>gi|88999583 myosin, light chain 6, alkali, smooth muscle and
           non-muscle isoform 2 [Homo sapiens]
          Length = 151

 Score = 57.0 bits (136), Expect = 7e-09
 Identities = 39/142 (27%), Positives = 72/142 (50%), Gaps = 4/142 (2%)

Query: 18  KIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEE-PTGYIRFEKF 76
           + KEAF++FD   +  +   + G ++R+LG  PT  E+  ++   + +E     + FE F
Sbjct: 11  EFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHF 70

Query: 77  LPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEM 136
           LP M + + + K +   ED  +    V D    G +   E+   +   GE  ++EE+ EM
Sbjct: 71  LP-MLQTVAKNKDQGTYED-YVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEV-EM 127

Query: 137 LSAAIDPESNSINYKDYITMMV 158
           L A  +  +  INY++ + M++
Sbjct: 128 LVAGHEDSNGCINYEELVRMVL 149


>gi|110611178 calcium binding protein 2 isoform 1 [Homo sapiens]
          Length = 220

 Score = 57.0 bits (136), Expect = 7e-09
 Identities = 45/157 (28%), Positives = 78/157 (49%), Gaps = 7/157 (4%)

Query: 2   ADEKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAE 61
           A + DRE  +  E  ++++ AF+ FD + +  +  RE+G  +R+LG  PTE EL     E
Sbjct: 68  ATQLDRE--LRPEEIEELQVAFQEFDRDRDGYIGCRELGACMRTLGYMPTEMEL----IE 121

Query: 62  VEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYM 121
           + ++   G + FE F+ +M   LL      I    L  AF   D+   G ++  EL   +
Sbjct: 122 ISQQISGGKVDFEDFVELMGPKLLAETADMIGVRELRDAFREFDTNGDGRISVGELRAAL 181

Query: 122 TE-EGEPFSQEEMEEMLSAAIDPESNSINYKDYITMM 157
               GE  SQ E++E+L          +++++++ MM
Sbjct: 182 KALLGERLSQREVDEILQDVDLNGDGLVDFEEFVRMM 218


>gi|21624641 calcium binding protein 4 [Homo sapiens]
          Length = 275

 Score = 55.8 bits (133), Expect = 2e-08
 Identities = 43/154 (27%), Positives = 78/154 (50%), Gaps = 4/154 (2%)

Query: 5   KDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEE 64
           KDRE  +  E   +++ AFE FD + +  +  RE+G  +R+LG  PTE EL ++   + +
Sbjct: 122 KDRE--LGPEELDELQAAFEEFDTDRDGYISHRELGDCMRTLGYMPTEMELLEVSQHI-K 178

Query: 65  EEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTE- 123
               G + FE+F+ ++   L E     +    L  AF   D  + G +T  EL + +   
Sbjct: 179 MRMGGRVDFEEFVELIGPKLREETAHMLGVRELRIAFREFDRDRDGRITVAELREAVPAL 238

Query: 124 EGEPFSQEEMEEMLSAAIDPESNSINYKDYITMM 157
            GEP +  E++EML         ++++ +++ M+
Sbjct: 239 LGEPLAGPELDEMLREVDLNGDGTVDFDEFVMML 272


>gi|169167243 PREDICTED: similar to myosin regulatory light chain
           MRCL2 [Homo sapiens]
          Length = 377

 Score = 54.7 bits (130), Expect = 3e-08
 Identities = 36/141 (25%), Positives = 68/141 (48%), Gaps = 9/141 (6%)

Query: 17  KKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKF 76
           ++ KEAF + D   +  +   ++  ++ SLG  PT+  L  ++      E  G I F   
Sbjct: 237 QEFKEAFNMIDQNRDGFISKEDLHGMLASLGKNPTDACLDAVM-----NEAPGPINFTML 291

Query: 77  LPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEM 136
           L +  + L        PEDV+  AF   D    G + +D L + +T  G+ F+ EE++E+
Sbjct: 292 LAMFGKKLNGTD----PEDVIRNAFACFDEEATGTIQEDYLRELLTTVGDQFTDEEVDEL 347

Query: 137 LSAAIDPESNSINYKDYITMM 157
            + A   +  + NY ++ +++
Sbjct: 348 YTEASIDKKGNFNYIEFTSIL 368


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.136    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,832,440
Number of Sequences: 37866
Number of extensions: 250410
Number of successful extensions: 884
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 742
Number of HSP's gapped (non-prelim): 130
length of query: 162
length of database: 18,247,518
effective HSP length: 94
effective length of query: 68
effective length of database: 14,688,114
effective search space: 998791752
effective search space used: 998791752
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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