BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|14150108 EF-hand calcium binding domain 2 isoform a [Homo sapiens] (162 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|14150108 EF-hand calcium binding domain 2 isoform a [Homo sap... 324 2e-89 gi|221316729 EF-hand calcium binding domain 2 isoform b [Homo sa... 249 7e-67 gi|58218968 calmodulin 3 [Homo sapiens] 96 1e-20 gi|4502549 calmodulin 2 [Homo sapiens] 96 1e-20 gi|5901912 calmodulin 1 [Homo sapiens] 96 1e-20 gi|4885111 calmodulin-like 3 [Homo sapiens] 96 2e-20 gi|4757974 centrin 1 [Homo sapiens] 80 8e-16 gi|4757902 caltractin [Homo sapiens] 79 1e-15 gi|4507617 fast skeletal muscle troponin C [Homo sapiens] 79 1e-15 gi|46397403 centrin 3 [Homo sapiens] 73 1e-13 gi|223278387 calmodulin-like 5 [Homo sapiens] 71 5e-13 gi|50897266 calmodulin-like 6 [Homo sapiens] 70 1e-12 gi|29568111 myosin regulatory light chain 9 isoform a [Homo sapi... 66 1e-11 gi|17986273 fast skeletal myosin alkali light chain 1 isoform 1f... 64 6e-11 gi|4507615 troponin C, slow [Homo sapiens] 64 7e-11 gi|17986275 fast skeletal myosin alkali light chain 1 isoform 3f... 63 1e-10 gi|4505303 smooth muscle and non-muscle myosin alkali light chai... 62 2e-10 gi|222144326 myosin regulatory light chain MRCL2 isoform A [Homo... 60 8e-10 gi|94981553 slow cardiac myosin regulatory light chain 2 [Homo s... 60 8e-10 gi|222144328 myosin regulatory light chain MRCL2 isoform B [Homo... 60 8e-10 gi|222144324 myosin regulatory light chain MRCL2 isoform A [Homo... 60 8e-10 gi|15809016 myosin regulatory light chain MRCL2 isoform A [Homo ... 60 8e-10 gi|11067753 calcium binding protein 5 [Homo sapiens] 60 1e-09 gi|5453740 myosin, light chain 12A, regulatory, non-sarcomeric [... 59 1e-09 gi|28372499 myosin light chain, phosphorylatable, fast skeletal ... 58 4e-09 gi|110611180 calcium binding protein 2 isoform 2 [Homo sapiens] 58 4e-09 gi|88999583 myosin, light chain 6, alkali, smooth muscle and non... 57 7e-09 gi|110611178 calcium binding protein 2 isoform 1 [Homo sapiens] 57 7e-09 gi|21624641 calcium binding protein 4 [Homo sapiens] 56 2e-08 gi|169167243 PREDICTED: similar to myosin regulatory light chain... 55 3e-08 >gi|14150108 EF-hand calcium binding domain 2 isoform a [Homo sapiens] Length = 162 Score = 324 bits (830), Expect = 2e-89 Identities = 162/162 (100%), Positives = 162/162 (100%) Query: 1 MADEKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIA 60 MADEKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIA Sbjct: 1 MADEKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIA 60 Query: 61 EVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKY 120 EVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKY Sbjct: 61 EVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKY 120 Query: 121 MTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYITMMVIDEN 162 MTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYITMMVIDEN Sbjct: 121 MTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYITMMVIDEN 162 >gi|221316729 EF-hand calcium binding domain 2 isoform b [Homo sapiens] Length = 133 Score = 249 bits (636), Expect = 7e-67 Identities = 124/124 (100%), Positives = 124/124 (100%) Query: 1 MADEKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIA 60 MADEKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIA Sbjct: 1 MADEKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIA 60 Query: 61 EVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKY 120 EVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKY Sbjct: 61 EVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKY 120 Query: 121 MTEE 124 MTEE Sbjct: 121 MTEE 124 >gi|58218968 calmodulin 3 [Homo sapiens] Length = 149 Score = 95.9 bits (237), Expect = 1e-20 Identities = 58/157 (36%), Positives = 89/157 (56%), Gaps = 11/157 (7%) Query: 1 MADEKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIA 60 MAD+ E+I AEF KEAF +FD + + T+ +E+GT++RSLG PTE EL D+I Sbjct: 1 MADQLTEEQI--AEF----KEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMIN 54 Query: 61 EVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKY 120 EV + + G I F +FL +M + + E+ + AF V D G+++ EL Sbjct: 55 EV-DADGNGTIDFPEFLTMMARKMKDTD----SEEEIREAFRVFDKDGNGYISAAELRHV 109 Query: 121 MTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYITMM 157 MT GE + EE++EM+ A +NY++++ MM Sbjct: 110 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146 >gi|4502549 calmodulin 2 [Homo sapiens] Length = 149 Score = 95.9 bits (237), Expect = 1e-20 Identities = 58/157 (36%), Positives = 89/157 (56%), Gaps = 11/157 (7%) Query: 1 MADEKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIA 60 MAD+ E+I AEF KEAF +FD + + T+ +E+GT++RSLG PTE EL D+I Sbjct: 1 MADQLTEEQI--AEF----KEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMIN 54 Query: 61 EVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKY 120 EV + + G I F +FL +M + + E+ + AF V D G+++ EL Sbjct: 55 EV-DADGNGTIDFPEFLTMMARKMKDTD----SEEEIREAFRVFDKDGNGYISAAELRHV 109 Query: 121 MTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYITMM 157 MT GE + EE++EM+ A +NY++++ MM Sbjct: 110 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146 >gi|5901912 calmodulin 1 [Homo sapiens] Length = 149 Score = 95.9 bits (237), Expect = 1e-20 Identities = 58/157 (36%), Positives = 89/157 (56%), Gaps = 11/157 (7%) Query: 1 MADEKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIA 60 MAD+ E+I AEF KEAF +FD + + T+ +E+GT++RSLG PTE EL D+I Sbjct: 1 MADQLTEEQI--AEF----KEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMIN 54 Query: 61 EVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKY 120 EV + + G I F +FL +M + + E+ + AF V D G+++ EL Sbjct: 55 EV-DADGNGTIDFPEFLTMMARKMKDTD----SEEEIREAFRVFDKDGNGYISAAELRHV 109 Query: 121 MTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYITMM 157 MT GE + EE++EM+ A +NY++++ MM Sbjct: 110 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 146 >gi|4885111 calmodulin-like 3 [Homo sapiens] Length = 149 Score = 95.5 bits (236), Expect = 2e-20 Identities = 56/158 (35%), Positives = 90/158 (56%), Gaps = 11/158 (6%) Query: 1 MADEKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIA 60 MAD+ E+ V EF KEAF +FD + + + RE+GT++RSLG PTE EL D+++ Sbjct: 1 MADQLTEEQ--VTEF----KEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMS 54 Query: 61 EVEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKY 120 E+ + + G + F +FL +M + + E+ + AF V D GF++ EL Sbjct: 55 EI-DRDGNGTVDFPEFLGMMARKMKDTD----NEEEIREAFRVFDKDGNGFVSAAELRHV 109 Query: 121 MTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYITMMV 158 MT GE S EE++EM+ AA +NY++++ ++V Sbjct: 110 MTRLGEKLSDEEVDEMIRAADTDGDGQVNYEEFVRVLV 147 >gi|4757974 centrin 1 [Homo sapiens] Length = 172 Score = 80.1 bits (196), Expect = 8e-16 Identities = 43/141 (30%), Positives = 83/141 (58%), Gaps = 5/141 (3%) Query: 17 KKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKF 76 ++++EAF++FD + + T+D +E+ +R+LG P + E+ +I+EV + E TG I F F Sbjct: 31 QEVREAFDLFDVDGSGTIDAKELKVAMRALGFEPRKEEMKKMISEV-DREGTGKISFNDF 89 Query: 77 LPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEM 136 L VMT+ + E+ ++ +L+AF + D + G ++ L + E GE + EE++EM Sbjct: 90 LAVMTQKMSEKD----TKEEILKAFRLFDDDETGKISFKNLKRVANELGENLTDEELQEM 145 Query: 137 LSAAIDPESNSINYKDYITMM 157 + A +N ++++ +M Sbjct: 146 IDEADRDGDGEVNEEEFLRIM 166 >gi|4757902 caltractin [Homo sapiens] Length = 172 Score = 79.3 bits (194), Expect = 1e-15 Identities = 43/147 (29%), Positives = 87/147 (59%), Gaps = 5/147 (3%) Query: 11 IVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGY 70 + E ++I+EAF++FD + T+DV+E+ +R+LG P + E+ +I+E+ ++E TG Sbjct: 25 LTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEI-DKEGTGK 83 Query: 71 IRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQ 130 + F FL VMT+ + E+ ++ +L+AF++ D + G ++ L + E GE + Sbjct: 84 MNFGDFLTVMTQKMSEKD----TKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTD 139 Query: 131 EEMEEMLSAAIDPESNSINYKDYITMM 157 EE++EM+ A ++ ++++ +M Sbjct: 140 EELQEMIDEADRDGDGEVSEQEFLRIM 166 >gi|4507617 fast skeletal muscle troponin C [Homo sapiens] Length = 160 Score = 79.3 bits (194), Expect = 1e-15 Identities = 47/149 (31%), Positives = 81/149 (54%), Gaps = 6/149 (4%) Query: 9 EIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPT 68 E ++AEF K AF++FD + + V+E+GT++R LG PT+ EL +I EV +E+ + Sbjct: 14 EEMIAEF----KAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEV-DEDGS 68 Query: 69 GYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPF 128 G I FE+FL +M + E + E+ L F + D G++ +EL + GE Sbjct: 69 GTIDFEEFLVMMVRQMKE-DAKGKSEEELAECFRIFDRNADGYIDPEELAEIFRASGEHV 127 Query: 129 SQEEMEEMLSAAIDPESNSINYKDYITMM 157 + EE+E ++ I++ +++ MM Sbjct: 128 TDEEIESLMKDGDKNNDGRIDFDEFLKMM 156 Score = 31.6 bits (70), Expect = 0.31 Identities = 15/59 (25%), Positives = 35/59 (59%) Query: 100 AFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYITMMV 158 AF++ D+ G ++ EL M G+ ++EE++ ++ + S +I++++++ MMV Sbjct: 23 AFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEVDEDGSGTIDFEEFLVMMV 81 >gi|46397403 centrin 3 [Homo sapiens] Length = 167 Score = 72.8 bits (177), Expect = 1e-13 Identities = 47/156 (30%), Positives = 82/156 (52%), Gaps = 6/156 (3%) Query: 5 KDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEE 64 K R E+ E ++IK+AFE+FD + + +D E+ +R+LG + ++ ++ + + Sbjct: 17 KKRRELS-EEQKQEIKDAFELFDTDKDEAIDYHELKVAMRALGFDVKKADVLKILKDYDR 75 Query: 65 EEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEE 124 E TG I FE F V+T+ +LER P + +L+AF++ D G ++ L + E Sbjct: 76 EA-TGKITFEDFNEVVTDWILERD----PHEEILKAFKLFDDDDSGKISLRNLRRVAREL 130 Query: 125 GEPFSQEEMEEMLSAAIDPESNSINYKDYITMMVID 160 GE S EE+ M+ IN +++I +M D Sbjct: 131 GENMSDEELRAMIEEFDKDGDGEINQEEFIAIMTGD 166 >gi|223278387 calmodulin-like 5 [Homo sapiens] Length = 146 Score = 70.9 bits (172), Expect = 5e-13 Identities = 44/147 (29%), Positives = 77/147 (52%), Gaps = 8/147 (5%) Query: 11 IVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGY 70 + E + K+AF D + N T++ +E+G +++ G +E +L LI+EV+ + G Sbjct: 5 LTPEEEAQYKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDGD-GE 63 Query: 71 IRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQ 130 I F++FL +K R ED+ + AF D G +T DEL + M G+P Q Sbjct: 64 ISFQEFLTAA------KKARAGLEDLQV-AFRAFDQDGDGHITVDELRRAMAGLGQPLPQ 116 Query: 131 EEMEEMLSAAIDPESNSINYKDYITMM 157 EE++ M+ A + +NY+++ M+ Sbjct: 117 EELDAMIREADVDQDGRVNYEEFARML 143 >gi|50897266 calmodulin-like 6 [Homo sapiens] Length = 181 Score = 69.7 bits (169), Expect = 1e-12 Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 4/152 (2%) Query: 6 DREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEE 65 D E + AE K+ K FE+FD E N V E+ ++ LG PT+ EL + +V+ + Sbjct: 25 DMTERLSAEQIKEYKGVFEMFDEEGNGEVKTGELEWLMSLLGINPTKSELASMAKDVDRD 84 Query: 66 EPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEG 125 G+ + FL +M + + E L AF V D +G++ + L + G Sbjct: 85 NK-GFFNCDGFLALMG---VYHEKAQNQESELRAAFRVFDKEGKGYIDWNTLKYVLMNAG 140 Query: 126 EPFSQEEMEEMLSAAIDPESNSINYKDYITMM 157 EP ++ E E+M+ A +I+Y++++ MM Sbjct: 141 EPLNEVEAEQMMKEADKDGDRTIDYEEFVAMM 172 >gi|29568111 myosin regulatory light chain 9 isoform a [Homo sapiens] Length = 172 Score = 65.9 bits (159), Expect = 1e-11 Identities = 41/141 (29%), Positives = 70/141 (49%), Gaps = 9/141 (6%) Query: 17 KKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKF 76 ++ KEAF + D + +D ++ ++ SLG PT+ L +++E G I F F Sbjct: 32 QEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDEYLEGMMSEAP-----GPINFTMF 86 Query: 77 LPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEM 136 L + E L PEDV+ AF D GF+ +D L + +T G+ F+ EE++EM Sbjct: 87 LTMFGEKLNGTD----PEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRFTDEEVDEM 142 Query: 137 LSAAIDPESNSINYKDYITMM 157 A + + NY ++ ++ Sbjct: 143 YREAPIDKKGNFNYVEFTRIL 163 >gi|17986273 fast skeletal myosin alkali light chain 1 isoform 1f [Homo sapiens] Length = 194 Score = 63.9 bits (154), Expect = 6e-11 Identities = 45/157 (28%), Positives = 77/157 (49%), Gaps = 8/157 (5%) Query: 3 DEKDREEIIVAEFHKK----IKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDL 58 +EK I EF K+ KEAF +FD ++ + + ++G ++R+LG PT E+ + Sbjct: 35 EEKIDLSAIKIEFSKEQQDEFKEAFLLFDRTGDSKITLSQVGDVLRALGTNPTNAEVRKV 94 Query: 59 IAEVEEEEPTG-YIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDEL 117 + EE I FE+FLP+M + + K + ED + V D G + EL Sbjct: 95 LGNPSNEELNAKKIEFEQFLPMM-QAISNNKDQATYED-FVEGLRVFDKEGNGTVMGAEL 152 Query: 118 IKYMTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYI 154 + GE +EE+E +++ D + INY+ ++ Sbjct: 153 RHVLATLGEKMKEEEVEALMAGQED-SNGCINYEAFV 188 >gi|4507615 troponin C, slow [Homo sapiens] Length = 161 Score = 63.5 bits (153), Expect = 7e-11 Identities = 39/150 (26%), Positives = 77/150 (51%), Gaps = 3/150 (2%) Query: 9 EIIVAEFHKKIKEAFEVFD-HESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEP 67 E + E + K AF++F + + +E+G ++R LG PT EL ++I EV+E+ Sbjct: 10 EQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDG- 68 Query: 68 TGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEP 127 +G + F++FL +M + + + E+ L F + D G++ DEL + GE Sbjct: 69 SGTVDFDEFLVMMVRCMKDDS-KGKSEEELSDLFRMFDKNADGYIDLDELKIMLQATGET 127 Query: 128 FSQEEMEEMLSAAIDPESNSINYKDYITMM 157 +++++EE++ I+Y +++ M Sbjct: 128 ITEDDIEELMKDGDKNNDGRIDYDEFLEFM 157 Score = 32.0 bits (71), Expect = 0.24 Identities = 15/52 (28%), Positives = 31/52 (59%) Query: 107 AKRGFLTKDELIKYMTEEGEPFSQEEMEEMLSAAIDPESNSINYKDYITMMV 158 A+ G ++ EL K M G+ + EE++EM+ + S ++++ +++ MMV Sbjct: 31 AEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMV 82 >gi|17986275 fast skeletal myosin alkali light chain 1 isoform 3f [Homo sapiens] Length = 150 Score = 63.2 bits (152), Expect = 1e-10 Identities = 42/144 (29%), Positives = 73/144 (50%), Gaps = 8/144 (5%) Query: 12 VAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTG-Y 70 +AEF KEAF +FD ++ + + ++G ++R+LG PT E+ ++ EE Sbjct: 8 IAEF----KEAFLLFDRTGDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAKK 63 Query: 71 IRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQ 130 I FE+FLP+M + + K + ED + V D G + EL + GE + Sbjct: 64 IEFEQFLPMM-QAISNNKDQATYED-FVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKE 121 Query: 131 EEMEEMLSAAIDPESNSINYKDYI 154 EE+E +++ D + INY+ ++ Sbjct: 122 EEVEALMAGQED-SNGCINYEAFV 144 >gi|4505303 smooth muscle and non-muscle myosin alkali light chain 6B [Homo sapiens] Length = 208 Score = 62.4 bits (150), Expect = 2e-10 Identities = 43/149 (28%), Positives = 75/149 (50%), Gaps = 8/149 (5%) Query: 11 IVAEFHK----KIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEE 66 +V EF+K + KEAFE+FD + + + G ++R+LG PT E+ ++ + +E Sbjct: 57 VVIEFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDE 116 Query: 67 -PTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEG 125 + + FE FLP++ + R + L F V D G + EL +T G Sbjct: 117 LKSRRVDFETFLPMLQAVAKNRGQGTYED--YLEGFRVFDKEGNGKVMGAELRHVLTTLG 174 Query: 126 EPFSQEEMEEMLSAAIDPESNSINYKDYI 154 E ++EE+E +L A + + INY+ ++ Sbjct: 175 EKMTEEEVETVL-AGHEDSNGCINYEAFL 202 >gi|222144326 myosin regulatory light chain MRCL2 isoform A [Homo sapiens] Length = 172 Score = 60.1 bits (144), Expect = 8e-10 Identities = 39/141 (27%), Positives = 68/141 (48%), Gaps = 9/141 (6%) Query: 17 KKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKF 76 ++ KEAF + D + +D ++ ++ SLG PT+ L ++ E G I F F Sbjct: 32 QEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMM-----NEAPGPINFTMF 86 Query: 77 LPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEM 136 L + E L PEDV+ AF D G + +D L + +T G+ F+ EE++E+ Sbjct: 87 LTMFGEKLNGTD----PEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDEL 142 Query: 137 LSAAIDPESNSINYKDYITMM 157 A + + NY ++ ++ Sbjct: 143 YREAPIDKKGNFNYIEFTRIL 163 >gi|94981553 slow cardiac myosin regulatory light chain 2 [Homo sapiens] Length = 166 Score = 60.1 bits (144), Expect = 8e-10 Identities = 41/145 (28%), Positives = 74/145 (51%), Gaps = 8/145 (5%) Query: 17 KKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKF 76 ++ KEAF + D + +D ++ +LG + E D E+ +E P G I F F Sbjct: 27 QEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEID---EMIKEAP-GPINFTVF 82 Query: 77 LPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEM 136 L + E L PE+ +L AF+V D +G L D + + +T + E FS+EE+++M Sbjct: 83 LTMFGEKLKGAD----PEETILNAFKVFDPEGKGVLKADYVREMLTTQAERFSKEEVDQM 138 Query: 137 LSAAIDPESNSINYKDYITMMVIDE 161 +A + +++YK+ + ++ E Sbjct: 139 FAAFPPDVTGNLDYKNLVHIITHGE 163 >gi|222144328 myosin regulatory light chain MRCL2 isoform B [Homo sapiens] Length = 154 Score = 60.1 bits (144), Expect = 8e-10 Identities = 39/141 (27%), Positives = 68/141 (48%), Gaps = 9/141 (6%) Query: 17 KKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKF 76 ++ KEAF + D + +D ++ ++ SLG PT+ L ++ E G I F F Sbjct: 14 QEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMM-----NEAPGPINFTMF 68 Query: 77 LPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEM 136 L + E L PEDV+ AF D G + +D L + +T G+ F+ EE++E+ Sbjct: 69 LTMFGEKLNGTD----PEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDEL 124 Query: 137 LSAAIDPESNSINYKDYITMM 157 A + + NY ++ ++ Sbjct: 125 YREAPIDKKGNFNYIEFTRIL 145 >gi|222144324 myosin regulatory light chain MRCL2 isoform A [Homo sapiens] Length = 172 Score = 60.1 bits (144), Expect = 8e-10 Identities = 39/141 (27%), Positives = 68/141 (48%), Gaps = 9/141 (6%) Query: 17 KKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKF 76 ++ KEAF + D + +D ++ ++ SLG PT+ L ++ E G I F F Sbjct: 32 QEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMM-----NEAPGPINFTMF 86 Query: 77 LPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEM 136 L + E L PEDV+ AF D G + +D L + +T G+ F+ EE++E+ Sbjct: 87 LTMFGEKLNGTD----PEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDEL 142 Query: 137 LSAAIDPESNSINYKDYITMM 157 A + + NY ++ ++ Sbjct: 143 YREAPIDKKGNFNYIEFTRIL 163 >gi|15809016 myosin regulatory light chain MRCL2 isoform A [Homo sapiens] Length = 172 Score = 60.1 bits (144), Expect = 8e-10 Identities = 39/141 (27%), Positives = 68/141 (48%), Gaps = 9/141 (6%) Query: 17 KKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKF 76 ++ KEAF + D + +D ++ ++ SLG PT+ L ++ E G I F F Sbjct: 32 QEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDAYLDAMM-----NEAPGPINFTMF 86 Query: 77 LPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEM 136 L + E L PEDV+ AF D G + +D L + +T G+ F+ EE++E+ Sbjct: 87 LTMFGEKLNGTD----PEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDEL 142 Query: 137 LSAAIDPESNSINYKDYITMM 157 A + + NY ++ ++ Sbjct: 143 YREAPIDKKGNFNYIEFTRIL 163 >gi|11067753 calcium binding protein 5 [Homo sapiens] Length = 173 Score = 59.7 bits (143), Expect = 1e-09 Identities = 41/155 (26%), Positives = 81/155 (52%), Gaps = 2/155 (1%) Query: 4 EKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVE 63 EK RE + + ++++EAF FD + + + +++G ++R++G PTE EL +L ++ Sbjct: 18 EKQRERPLGQDEIEELREAFLEFDKDRDGFISCKDLGNLMRTMGYMPTEMELIELGQQI- 76 Query: 64 EEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTE 123 G + F+ F+ +MT LL I + AF+ D+ G +T EL + M Sbjct: 77 RMNLGGRVDFDDFVELMTPKLLAETAGMIGVQEMRDAFKEFDTNGDGEITLVELQQAMQR 136 Query: 124 -EGEPFSQEEMEEMLSAAIDPESNSINYKDYITMM 157 GE + E+ E++ A ++++++++ MM Sbjct: 137 LLGERLTPREISEVVREADVNGDGTVDFEEFVKMM 171 >gi|5453740 myosin, light chain 12A, regulatory, non-sarcomeric [Homo sapiens] Length = 171 Score = 59.3 bits (142), Expect = 1e-09 Identities = 39/141 (27%), Positives = 68/141 (48%), Gaps = 9/141 (6%) Query: 17 KKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKF 76 ++ KEAF + D + +D ++ ++ SLG PT+ L ++ E G I F F Sbjct: 31 QEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDEYLDAMM-----NEAPGPINFTMF 85 Query: 77 LPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEM 136 L + E L PEDV+ AF D G + +D L + +T G+ F+ EE++E+ Sbjct: 86 LTMFGEKLNGTD----PEDVIRNAFACFDEEATGTIQEDYLRELLTTMGDRFTDEEVDEL 141 Query: 137 LSAAIDPESNSINYKDYITMM 157 A + + NY ++ ++ Sbjct: 142 YREAPIDKKGNFNYIEFTRIL 162 >gi|28372499 myosin light chain, phosphorylatable, fast skeletal muscle [Homo sapiens] Length = 169 Score = 57.8 bits (138), Expect = 4e-09 Identities = 40/136 (29%), Positives = 68/136 (50%), Gaps = 8/136 (5%) Query: 17 KKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKF 76 ++ KEAF V D + +D ++ ++G + E D + + E +G I F F Sbjct: 28 QEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKNEELDAMMK----EASGPINFTVF 83 Query: 77 LPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEM 136 L + E L PEDV+ AF+VLD +G + K L + +T + + FSQEE++ M Sbjct: 84 LTMFGEKLKGAD----PEDVITGAFKVLDPEGKGTIKKKFLEELLTTQCDRFSQEEIKNM 139 Query: 137 LSAAIDPESNSINYKD 152 +A +++YK+ Sbjct: 140 WAAFPPDVGGNVDYKN 155 >gi|110611180 calcium binding protein 2 isoform 2 [Homo sapiens] Length = 163 Score = 57.8 bits (138), Expect = 4e-09 Identities = 45/154 (29%), Positives = 77/154 (50%), Gaps = 7/154 (4%) Query: 5 KDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEE 64 KDRE + E ++++ AF+ FD + + + RE+G +R+LG PTE EL E+ + Sbjct: 14 KDRE--LRPEEIEELQVAFQEFDRDRDGYIGCRELGACMRTLGYMPTEMEL----IEISQ 67 Query: 65 EEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTE- 123 + G + FE F+ +M LL I L AF D+ G ++ EL + Sbjct: 68 QISGGKVDFEDFVELMGPKLLAETADMIGVRELRDAFREFDTNGDGRISVGELRAALKAL 127 Query: 124 EGEPFSQEEMEEMLSAAIDPESNSINYKDYITMM 157 GE SQ E++E+L +++++++ MM Sbjct: 128 LGERLSQREVDEILQDVDLNGDGLVDFEEFVRMM 161 >gi|88999583 myosin, light chain 6, alkali, smooth muscle and non-muscle isoform 2 [Homo sapiens] Length = 151 Score = 57.0 bits (136), Expect = 7e-09 Identities = 39/142 (27%), Positives = 72/142 (50%), Gaps = 4/142 (2%) Query: 18 KIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEE-PTGYIRFEKF 76 + KEAF++FD + + + G ++R+LG PT E+ ++ + +E + FE F Sbjct: 11 EFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHF 70 Query: 77 LPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEM 136 LP M + + + K + ED + V D G + E+ + GE ++EE+ EM Sbjct: 71 LP-MLQTVAKNKDQGTYED-YVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEV-EM 127 Query: 137 LSAAIDPESNSINYKDYITMMV 158 L A + + INY++ + M++ Sbjct: 128 LVAGHEDSNGCINYEELVRMVL 149 >gi|110611178 calcium binding protein 2 isoform 1 [Homo sapiens] Length = 220 Score = 57.0 bits (136), Expect = 7e-09 Identities = 45/157 (28%), Positives = 78/157 (49%), Gaps = 7/157 (4%) Query: 2 ADEKDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAE 61 A + DRE + E ++++ AF+ FD + + + RE+G +R+LG PTE EL E Sbjct: 68 ATQLDRE--LRPEEIEELQVAFQEFDRDRDGYIGCRELGACMRTLGYMPTEMEL----IE 121 Query: 62 VEEEEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYM 121 + ++ G + FE F+ +M LL I L AF D+ G ++ EL + Sbjct: 122 ISQQISGGKVDFEDFVELMGPKLLAETADMIGVRELRDAFREFDTNGDGRISVGELRAAL 181 Query: 122 TE-EGEPFSQEEMEEMLSAAIDPESNSINYKDYITMM 157 GE SQ E++E+L +++++++ MM Sbjct: 182 KALLGERLSQREVDEILQDVDLNGDGLVDFEEFVRMM 218 >gi|21624641 calcium binding protein 4 [Homo sapiens] Length = 275 Score = 55.8 bits (133), Expect = 2e-08 Identities = 43/154 (27%), Positives = 78/154 (50%), Gaps = 4/154 (2%) Query: 5 KDREEIIVAEFHKKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEE 64 KDRE + E +++ AFE FD + + + RE+G +R+LG PTE EL ++ + + Sbjct: 122 KDRE--LGPEELDELQAAFEEFDTDRDGYISHRELGDCMRTLGYMPTEMELLEVSQHI-K 178 Query: 65 EEPTGYIRFEKFLPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTE- 123 G + FE+F+ ++ L E + L AF D + G +T EL + + Sbjct: 179 MRMGGRVDFEEFVELIGPKLREETAHMLGVRELRIAFREFDRDRDGRITVAELREAVPAL 238 Query: 124 EGEPFSQEEMEEMLSAAIDPESNSINYKDYITMM 157 GEP + E++EML ++++ +++ M+ Sbjct: 239 LGEPLAGPELDEMLREVDLNGDGTVDFDEFVMML 272 >gi|169167243 PREDICTED: similar to myosin regulatory light chain MRCL2 [Homo sapiens] Length = 377 Score = 54.7 bits (130), Expect = 3e-08 Identities = 36/141 (25%), Positives = 68/141 (48%), Gaps = 9/141 (6%) Query: 17 KKIKEAFEVFDHESNNTVDVREIGTIIRSLGCCPTEGELHDLIAEVEEEEPTGYIRFEKF 76 ++ KEAF + D + + ++ ++ SLG PT+ L ++ E G I F Sbjct: 237 QEFKEAFNMIDQNRDGFISKEDLHGMLASLGKNPTDACLDAVM-----NEAPGPINFTML 291 Query: 77 LPVMTEILLERKYRPIPEDVLLRAFEVLDSAKRGFLTKDELIKYMTEEGEPFSQEEMEEM 136 L + + L PEDV+ AF D G + +D L + +T G+ F+ EE++E+ Sbjct: 292 LAMFGKKLNGTD----PEDVIRNAFACFDEEATGTIQEDYLRELLTTVGDQFTDEEVDEL 347 Query: 137 LSAAIDPESNSINYKDYITMM 157 + A + + NY ++ +++ Sbjct: 348 YTEASIDKKGNFNYIEFTSIL 368 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.136 0.375 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 5,832,440 Number of Sequences: 37866 Number of extensions: 250410 Number of successful extensions: 884 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 60 Number of HSP's successfully gapped in prelim test: 42 Number of HSP's that attempted gapping in prelim test: 742 Number of HSP's gapped (non-prelim): 130 length of query: 162 length of database: 18,247,518 effective HSP length: 94 effective length of query: 68 effective length of database: 14,688,114 effective search space: 998791752 effective search space used: 998791752 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.