BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|14149904 anthrax toxin receptor 1 isoform 1 precursor [Homo sapiens] (564 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|14149904 anthrax toxin receptor 1 isoform 1 precursor [Homo s... 1169 0.0 gi|16933551 anthrax toxin receptor 1 isoform 2 precursor [Homo s... 734 0.0 gi|16933553 anthrax toxin receptor 1 isoform 3 precursor [Homo s... 639 0.0 gi|50513243 anthrax toxin receptor 2 isoform 1 [Homo sapiens] 548 e-156 gi|224809466 anthrax toxin receptor 2 isoform 2 [Homo sapiens] 531 e-151 gi|157168329 formin 1 [Homo sapiens] 69 1e-11 gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 68 3e-11 gi|11386183 WAS protein family, member 2 [Homo sapiens] 67 4e-11 gi|153792074 proline rich 12 [Homo sapiens] 67 6e-11 gi|56549694 enabled homolog isoform a [Homo sapiens] 66 7e-11 gi|39930375 enabled homolog isoform b [Homo sapiens] 66 7e-11 gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 66 7e-11 gi|55741677 SET domain containing 1A [Homo sapiens] 65 2e-10 gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 64 4e-10 gi|150417989 cyclin K isoform 1 [Homo sapiens] 64 4e-10 gi|210032580 SET domain containing 1B [Homo sapiens] 64 5e-10 gi|33356148 formin-like 1 [Homo sapiens] 63 6e-10 gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 63 8e-10 gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 63 8e-10 gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 63 8e-10 gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 62 1e-09 gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 62 2e-09 gi|52485606 formin-like 2 [Homo sapiens] 62 2e-09 gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 62 2e-09 gi|169163027 PREDICTED: similar to Putative acrosin-like proteas... 60 4e-09 gi|239753435 PREDICTED: hypothetical protein XP_002345651 [Homo ... 60 5e-09 gi|239747993 PREDICTED: hypothetical protein XP_002346504 [Homo ... 60 5e-09 gi|239741891 PREDICTED: hypothetical protein XP_002342316 [Homo ... 60 5e-09 gi|7706501 WW domain binding protein 11 [Homo sapiens] 60 7e-09 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 59 9e-09 >gi|14149904 anthrax toxin receptor 1 isoform 1 precursor [Homo sapiens] Length = 564 Score = 1169 bits (3025), Expect = 0.0 Identities = 564/564 (100%), Positives = 564/564 (100%) Query: 1 MATAERRALGIGFQWLSLATLVLICAGQGGRREDGGPACYGGFDLYFILDKSGSVLHHWN 60 MATAERRALGIGFQWLSLATLVLICAGQGGRREDGGPACYGGFDLYFILDKSGSVLHHWN Sbjct: 1 MATAERRALGIGFQWLSLATLVLICAGQGGRREDGGPACYGGFDLYFILDKSGSVLHHWN 60 Query: 61 EIYYFVEQLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYM 120 EIYYFVEQLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYM Sbjct: 61 EIYYFVEQLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYM 120 Query: 121 HEGFERASEQIYYENRQGYRTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGV 180 HEGFERASEQIYYENRQGYRTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGV Sbjct: 121 HEGFERASEQIYYENRQGYRTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGV 180 Query: 181 KDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVV 240 KDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVV Sbjct: 181 KDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVV 240 Query: 241 VRGNGFRHARNVDRVLCSFKINDSVTLNEKPFSVEDTYLLCPAPILKEVGMKAALQVSMN 300 VRGNGFRHARNVDRVLCSFKINDSVTLNEKPFSVEDTYLLCPAPILKEVGMKAALQVSMN Sbjct: 241 VRGNGFRHARNVDRVLCSFKINDSVTLNEKPFSVEDTYLLCPAPILKEVGMKAALQVSMN 300 Query: 301 DGLSFISSSVIITTTHCSDGSILAIALLILFLLLALALLWWFWPLCCTVIIKEVPPPPAE 360 DGLSFISSSVIITTTHCSDGSILAIALLILFLLLALALLWWFWPLCCTVIIKEVPPPPAE Sbjct: 301 DGLSFISSSVIITTTHCSDGSILAIALLILFLLLALALLWWFWPLCCTVIIKEVPPPPAE 360 Query: 361 ESEEEDDDGLPKKKWPTVDASYYGGRGVGGIKRMEVRWGEKGSTEEGAKLEKAKNARVKM 420 ESEEEDDDGLPKKKWPTVDASYYGGRGVGGIKRMEVRWGEKGSTEEGAKLEKAKNARVKM Sbjct: 361 ESEEEDDDGLPKKKWPTVDASYYGGRGVGGIKRMEVRWGEKGSTEEGAKLEKAKNARVKM 420 Query: 421 PEQEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQPGDTGR 480 PEQEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQPGDTGR Sbjct: 421 PEQEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQPGDTGR 480 Query: 481 CINFTRVKNNQPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTL 540 CINFTRVKNNQPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTL Sbjct: 481 CINFTRVKNNQPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTL 540 Query: 541 PPPPQAPPPNRAPPPSRPPPRPSV 564 PPPPQAPPPNRAPPPSRPPPRPSV Sbjct: 541 PPPPQAPPPNRAPPPSRPPPRPSV 564 >gi|16933551 anthrax toxin receptor 1 isoform 2 precursor [Homo sapiens] Length = 368 Score = 734 bits (1894), Expect = 0.0 Identities = 364/364 (100%), Positives = 364/364 (100%) Query: 1 MATAERRALGIGFQWLSLATLVLICAGQGGRREDGGPACYGGFDLYFILDKSGSVLHHWN 60 MATAERRALGIGFQWLSLATLVLICAGQGGRREDGGPACYGGFDLYFILDKSGSVLHHWN Sbjct: 1 MATAERRALGIGFQWLSLATLVLICAGQGGRREDGGPACYGGFDLYFILDKSGSVLHHWN 60 Query: 61 EIYYFVEQLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYM 120 EIYYFVEQLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYM Sbjct: 61 EIYYFVEQLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYM 120 Query: 121 HEGFERASEQIYYENRQGYRTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGV 180 HEGFERASEQIYYENRQGYRTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGV Sbjct: 121 HEGFERASEQIYYENRQGYRTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGV 180 Query: 181 KDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVV 240 KDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVV Sbjct: 181 KDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVV 240 Query: 241 VRGNGFRHARNVDRVLCSFKINDSVTLNEKPFSVEDTYLLCPAPILKEVGMKAALQVSMN 300 VRGNGFRHARNVDRVLCSFKINDSVTLNEKPFSVEDTYLLCPAPILKEVGMKAALQVSMN Sbjct: 241 VRGNGFRHARNVDRVLCSFKINDSVTLNEKPFSVEDTYLLCPAPILKEVGMKAALQVSMN 300 Query: 301 DGLSFISSSVIITTTHCSDGSILAIALLILFLLLALALLWWFWPLCCTVIIKEVPPPPAE 360 DGLSFISSSVIITTTHCSDGSILAIALLILFLLLALALLWWFWPLCCTVIIKEVPPPPAE Sbjct: 301 DGLSFISSSVIITTTHCSDGSILAIALLILFLLLALALLWWFWPLCCTVIIKEVPPPPAE 360 Query: 361 ESEE 364 ESEE Sbjct: 361 ESEE 364 >gi|16933553 anthrax toxin receptor 1 isoform 3 precursor [Homo sapiens] Length = 333 Score = 639 bits (1649), Expect = 0.0 Identities = 318/318 (100%), Positives = 318/318 (100%) Query: 1 MATAERRALGIGFQWLSLATLVLICAGQGGRREDGGPACYGGFDLYFILDKSGSVLHHWN 60 MATAERRALGIGFQWLSLATLVLICAGQGGRREDGGPACYGGFDLYFILDKSGSVLHHWN Sbjct: 1 MATAERRALGIGFQWLSLATLVLICAGQGGRREDGGPACYGGFDLYFILDKSGSVLHHWN 60 Query: 61 EIYYFVEQLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYM 120 EIYYFVEQLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYM Sbjct: 61 EIYYFVEQLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYM 120 Query: 121 HEGFERASEQIYYENRQGYRTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGV 180 HEGFERASEQIYYENRQGYRTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGV Sbjct: 121 HEGFERASEQIYYENRQGYRTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGV 180 Query: 181 KDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVV 240 KDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVV Sbjct: 181 KDFNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVV 240 Query: 241 VRGNGFRHARNVDRVLCSFKINDSVTLNEKPFSVEDTYLLCPAPILKEVGMKAALQVSMN 300 VRGNGFRHARNVDRVLCSFKINDSVTLNEKPFSVEDTYLLCPAPILKEVGMKAALQVSMN Sbjct: 241 VRGNGFRHARNVDRVLCSFKINDSVTLNEKPFSVEDTYLLCPAPILKEVGMKAALQVSMN 300 Query: 301 DGLSFISSSVIITTTHCS 318 DGLSFISSSVIITTTHCS Sbjct: 301 DGLSFISSSVIITTTHCS 318 >gi|50513243 anthrax toxin receptor 2 isoform 1 [Homo sapiens] Length = 488 Score = 548 bits (1412), Expect = e-156 Identities = 273/485 (56%), Positives = 349/485 (71%), Gaps = 3/485 (0%) Query: 4 AERRALGIGFQWLSLATLVLICAGQGGR-REDGGPACYGGFDLYFILDKSGSVLHHWNEI 62 AER WL +L+ +G GG R P+C FDLYF+LDKSGSV ++W EI Sbjct: 3 AERSPARSPGSWLFPGLWLLVLSGPGGLLRAQEQPSCRRAFDLYFVLDKSGSVANNWIEI 62 Query: 63 YYFVEQLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHE 122 Y FV+QLA +F+SP++R+SFIVFS++ T ++ LT DR +I +GLE+L++V P G+TY+HE Sbjct: 63 YNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLEDLKRVSPVGETYIHE 122 Query: 123 GFERASEQIYYENRQGYRTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKD 182 G + A+EQI + G +T+S+IIALTDG+L + Y+E+EA SR LGA VYCVGV D Sbjct: 123 GLKLANEQI--QKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVGVLD 180 Query: 183 FNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVR 242 F + QL RIADSK+ VFPV GFQAL+GII+SIL +SC EIL +PS++C GE FQ+V+ Sbjct: 181 FEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQIVLS 240 Query: 243 GNGFRHARNVDRVLCSFKINDSVTLNEKPFSVEDTYLLCPAPILKEVGMKAALQVSMNDG 302 G GF VLC++ +N++ T + KP SV+ +LCPAPIL + G + VS N G Sbjct: 241 GRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKAGETLDVSVSFNGG 300 Query: 303 LSFISSSVIITTTHCSDGSILAIALLILFLLLALALLWWFWPLCCTVIIKEVPPPPAEES 362 S IS S+I+T T CS+G I +L+L LLL + L+WWFWPLCC V+IK+ PPPPA Sbjct: 301 KSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKVVIKDPPPPPAPAP 360 Query: 363 EEEDDDGLPKKKWPTVDASYYGGRGVGGIKRMEVRWGEKGSTEEGAKLEKAKNARVKMPE 422 +EE+++ LP KKWPTVDASYYGGRGVGGIKRMEVRWG+KGSTEEGA+LEKAKNA VK+PE Sbjct: 361 KEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGARLEKAKNAVVKIPE 420 Query: 423 QEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQPGDTGRCI 482 + E PR KWY+PIKG+LDALW LLR+ YDRVS+MRPQ GD GRCI Sbjct: 421 ETEEPIRPRPPRPKPTHQPPQTKWYTPIKGRLDALWALLRRQYDRVSLMRPQEGDEGRCI 480 Query: 483 NFTRV 487 NF+RV Sbjct: 481 NFSRV 485 >gi|224809466 anthrax toxin receptor 2 isoform 2 [Homo sapiens] Length = 489 Score = 531 bits (1367), Expect = e-151 Identities = 265/475 (55%), Positives = 340/475 (71%), Gaps = 3/475 (0%) Query: 4 AERRALGIGFQWLSLATLVLICAGQGGR-REDGGPACYGGFDLYFILDKSGSVLHHWNEI 62 AER WL +L+ +G GG R P+C FDLYF+LDKSGSV ++W EI Sbjct: 3 AERSPARSPGSWLFPGLWLLVLSGPGGLLRAQEQPSCRRAFDLYFVLDKSGSVANNWIEI 62 Query: 63 YYFVEQLAHKFISPQLRMSFIVFSTRGTTLMKLTEDREQIRQGLEELQKVLPGGDTYMHE 122 Y FV+QLA +F+SP++R+SFIVFS++ T ++ LT DR +I +GLE+L++V P G+TY+HE Sbjct: 63 YNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLEDLKRVSPVGETYIHE 122 Query: 123 GFERASEQIYYENRQGYRTASVIIALTDGELHEDLFFYSEREANRSRDLGAIVYCVGVKD 182 G + A+EQI + G +T+S+IIALTDG+L + Y+E+EA SR LGA VYCVGV D Sbjct: 123 GLKLANEQI--QKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVGVLD 180 Query: 183 FNETQLARIADSKDHVFPVNDGFQALQGIIHSILKKSCIEILAAEPSTICAGESFQVVVR 242 F + QL RIADSK+ VFPV GFQAL+GII+SIL +SC EIL +PS++C GE FQ+V+ Sbjct: 181 FEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQIVLS 240 Query: 243 GNGFRHARNVDRVLCSFKINDSVTLNEKPFSVEDTYLLCPAPILKEVGMKAALQVSMNDG 302 G GF VLC++ +N++ T + KP SV+ +LCPAPIL + G + VS N G Sbjct: 241 GRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKAGETLDVSVSFNGG 300 Query: 303 LSFISSSVIITTTHCSDGSILAIALLILFLLLALALLWWFWPLCCTVIIKEVPPPPAEES 362 S IS S+I+T T CS+G I +L+L LLL + L+WWFWPLCC V+IK+ PPPPA Sbjct: 301 KSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKVVIKDPPPPPAPAP 360 Query: 363 EEEDDDGLPKKKWPTVDASYYGGRGVGGIKRMEVRWGEKGSTEEGAKLEKAKNARVKMPE 422 +EE+++ LP KKWPTVDASYYGGRGVGGIKRMEVRWG+KGSTEEGA+LEKAKNA VK+PE Sbjct: 361 KEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGARLEKAKNAVVKIPE 420 Query: 423 QEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQPGD 477 + E PR KWY+PIKG+LDALW LLR+ YDRVS+MRPQ GD Sbjct: 421 ETEEPIRPRPPRPKPTHQPPQTKWYTPIKGRLDALWALLRRQYDRVSLMRPQEGD 475 >gi|157168329 formin 1 [Homo sapiens] Length = 1196 Score = 68.9 bits (167), Expect = 1e-11 Identities = 36/79 (45%), Positives = 41/79 (51%), Gaps = 11/79 (13%) Query: 491 QPAKYPLNNAYHTSSPPPAPIYTPPPPAPH-------CPPPPPSAPTPPIPSPPSTLPPP 543 QP + +N PPPA I PPPP P PP PP + PP+P PP PPP Sbjct: 632 QPMEGMASNQQKALPPPPASI-PPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPP---PPP 687 Query: 544 PQAPPPNRAPPPSRPPPRP 562 P PPP+ A PP PPP P Sbjct: 688 PPLPPPSSAGPPPPPPPPP 706 Score = 65.5 bits (158), Expect = 1e-10 Identities = 31/68 (45%), Positives = 36/68 (52%), Gaps = 2/68 (2%) Query: 492 PAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNR 551 P P++ PPP P PPP + PPPPP P P P+PP+ PPP PPP Sbjct: 669 PPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGL 728 Query: 552 APPPSRPP 559 APPP PP Sbjct: 729 APPP--PP 734 Score = 64.3 bits (155), Expect = 3e-10 Identities = 34/84 (40%), Positives = 39/84 (46%), Gaps = 11/84 (13%) Query: 492 PAKYPLNNAYHTSSPPPA--------PIYTPPPPAPHCPPPPPSAPTPPIPSPP---STL 540 P PL + + SP P P+ PPPP P PPP + P PP P PP S Sbjct: 653 PPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPA 712 Query: 541 PPPPQAPPPNRAPPPSRPPPRPSV 564 PP P PPP PP PPP P + Sbjct: 713 PPNPGGPPPAPPPPGLAPPPPPGL 736 Score = 30.8 bits (68), Expect = 3.4 Identities = 14/32 (43%), Positives = 19/32 (59%), Gaps = 2/32 (6%) Query: 533 IPSPPSTLPPPPQAPPPNRAPPPSRPPPRPSV 564 +P PP+++PPPP P P+ S PP P V Sbjct: 645 LPPPPASIPPPP--PLPSGLGSLSPAPPMPPV 674 Score = 30.8 bits (68), Expect = 3.4 Identities = 22/58 (37%), Positives = 23/58 (39%), Gaps = 5/58 (8%) Query: 492 PAKYPLNNAYHTSSPPPAPIYTPP-PPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPP 548 P PL N S PP P PP PP P PPPP + S S P P P Sbjct: 702 PPPPPLPN----SPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEP 755 >gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD subunit [Homo sapiens] Length = 551 Score = 67.8 bits (164), Expect = 3e-11 Identities = 37/80 (46%), Positives = 37/80 (46%), Gaps = 10/80 (12%) Query: 491 QPAKYPLNNAYHTSSPPPAPIYTPP--PPAPHCPPPPPSAPTPPIP----SPPSTLPPPP 544 QP P PPP P Y PP PP P PPPP P PP P PP TL PPP Sbjct: 282 QPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPP 341 Query: 545 QAPPPNRAPPPSRPPPRPSV 564 P PPP PPP P V Sbjct: 342 HLP----GPPPGAPPPAPHV 357 Score = 55.1 bits (131), Expect = 2e-07 Identities = 28/55 (50%), Positives = 29/55 (52%), Gaps = 6/55 (10%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPP 560 PPP P PP P PP PP P PP PP + PPP A PPNR RPPP Sbjct: 227 PPPFPAGQTPPRPPLGPPGPPGPPGPP---PPGQVLPPPLAGPPNRG---DRPPP 275 Score = 53.9 bits (128), Expect = 4e-07 Identities = 27/79 (34%), Positives = 32/79 (40%), Gaps = 22/79 (27%) Query: 505 SPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPST----------------------LPP 542 +PP P+ P PP P PPPP PP+ PP+ LPP Sbjct: 235 TPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPP 294 Query: 543 PPQAPPPNRAPPPSRPPPR 561 P P P PPP PPP+ Sbjct: 295 GPPPPVPGYGPPPGPPPPQ 313 Score = 53.9 bits (128), Expect = 4e-07 Identities = 30/73 (41%), Positives = 32/73 (43%), Gaps = 9/73 (12%) Query: 496 PLNNAYHTSSPPPAPIYTP------PPPAPHCPPPPPSAP---TPPIPSPPSTLPPPPQA 546 PL + PP P+ P PP P P PPP P PP P PP PPPP Sbjct: 262 PLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPG 321 Query: 547 PPPNRAPPPSRPP 559 P P R P P PP Sbjct: 322 PFPPRPPGPLGPP 334 Score = 52.4 bits (124), Expect = 1e-06 Identities = 28/70 (40%), Positives = 32/70 (45%), Gaps = 13/70 (18%) Query: 506 PPPAPIYTPPP----------PAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPP---NRA 552 PPP P PP P PH P PPP AP P P+ PPP + P +R Sbjct: 318 PPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRG 377 Query: 553 PPPSRPPPRP 562 PPP+ P RP Sbjct: 378 PPPTDPYGRP 387 Score = 37.0 bits (84), Expect = 0.048 Identities = 27/67 (40%), Positives = 30/67 (44%), Gaps = 15/67 (22%) Query: 502 HTSSPPPAPIYTPPPPAPHCPP---PPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSR- 557 H PPP PPPAPH P PPP+ +P+ S PPP P R PP R Sbjct: 342 HLPGPPPGA----PPPAPHVNPAFFPPPTNS--GMPTSDSRGPPP--TDPYGRPPPYDRG 393 Query: 558 ---PPPR 561 PP R Sbjct: 394 DYGPPGR 400 >gi|11386183 WAS protein family, member 2 [Homo sapiens] Length = 498 Score = 67.0 bits (162), Expect = 4e-11 Identities = 33/67 (49%), Positives = 36/67 (53%), Gaps = 10/67 (14%) Query: 506 PPPAPIY-----TPPPPAPHCPPPPPSAPTPPIPSPPS-----TLPPPPQAPPPNRAPPP 555 PPP P+ TPPPP+P PP P PP P PP TLPPPP + P APPP Sbjct: 334 PPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPP 393 Query: 556 SRPPPRP 562 PPP P Sbjct: 394 PPPPPPP 400 Score = 63.2 bits (152), Expect = 6e-10 Identities = 31/72 (43%), Positives = 37/72 (51%), Gaps = 3/72 (4%) Query: 492 PAKYPLNNAYHTSSPPPAPIYTPPPP---APHCPPPPPSAPTPPIPSPPSTLPPPPQAPP 548 P P+ + PPP+P PP P AP PPPPP+A P +P PP + P PP Sbjct: 334 PPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPP 393 Query: 549 PNRAPPPSRPPP 560 P PPP PPP Sbjct: 394 PPPPPPPGPPPP 405 Score = 60.5 bits (145), Expect = 4e-09 Identities = 34/66 (51%), Positives = 36/66 (54%), Gaps = 11/66 (16%) Query: 505 SPPPAPIYTPPPPAPHCPPPPP-----SAPTPPIPSPPSTLP-----PPPQAPPPNRAPP 554 +PPPAP PPPP PPPPP S TPP PSPPS P PP PPP A Sbjct: 317 APPPAPP-PPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADY 375 Query: 555 PSRPPP 560 P+ PPP Sbjct: 376 PTLPPP 381 Score = 47.8 bits (112), Expect = 3e-05 Identities = 29/62 (46%), Positives = 32/62 (51%), Gaps = 9/62 (14%) Query: 504 SSPPPAPIYTPPPPA--PHCPPPPPSAPT---PPIPSPPSTLPPPPQAPPPNRAPPPSRP 558 ++PPP P PPP A P PPPP S PT PP P PP P PP P P+ P Sbjct: 362 AAPPPPP---PPPAADYPTLPPPPLSQPTGGAPPPPPPPPP-PGPPPPPFTGADGQPAIP 417 Query: 559 PP 560 PP Sbjct: 418 PP 419 Score = 45.8 bits (107), Expect = 1e-04 Identities = 60/233 (25%), Positives = 79/233 (33%), Gaps = 52/233 (22%) Query: 356 PPPAEESEEEDDDGLPKKKWPTVDASYYGGRGVGGIKRMEVRWGEKGSTEEGAKLEKAKN 415 PPP DDG K+ T D SY+ W EK L+ K+ Sbjct: 130 PPPLNNLTPYRDDGKEALKFYT-DPSYFFDL-----------WKEK-------MLQDTKD 170 Query: 416 ARVKMPEQEYEFPEPRNLNNNMRRPSSPRK--WYSPIKGK--LDALWVLLRKGYDRVSVM 471 + + E + N N R RK W G+ +++ L GY V Sbjct: 171 IMKEKRKHRKEKKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKEKLGTSGYPPTLVY 230 Query: 472 RPQPGDTGRCINFTRVKNNQPAKYPLNNAYHTSSPPPAPIYTPPPPA------------- 518 Q G G C+ + P P +++ + SP + PPPPA Sbjct: 231 --QNGSIG-CVENVDASSYPPP--PQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSG 285 Query: 519 -----------PHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPP 560 P PPP P +PP P P PP P PPP P PPP Sbjct: 286 LAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPP 338 Score = 38.9 bits (89), Expect = 0.013 Identities = 19/45 (42%), Positives = 20/45 (44%), Gaps = 2/45 (4%) Query: 501 YHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPS--TLPPP 543 Y T PPP T P P PPPPP P PP +PPP Sbjct: 375 YPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPP 419 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 66.6 bits (161), Expect = 6e-11 Identities = 34/77 (44%), Positives = 42/77 (54%), Gaps = 3/77 (3%) Query: 489 NNQPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPP--IPSPPSTLPPPPQA 546 +N + PL +PPPAP P PP P PPP P+ P+PP + PS+ PPPP Sbjct: 1444 SNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPP-PPPQPALPSPPPLVAPTPSSPPPPPLP 1502 Query: 547 PPPNRAPPPSRPPPRPS 563 PPP A P PPP P+ Sbjct: 1503 PPPPPAMPSPPPPPPPA 1519 Score = 63.9 bits (154), Expect = 4e-10 Identities = 30/60 (50%), Positives = 35/60 (58%), Gaps = 8/60 (13%) Query: 506 PPPAPIYTPPPPAPHC-PPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPPRPSV 564 PPP P PP P P PPPPP P P +PSPP + P P +PPP PP PPP P++ Sbjct: 1457 PPPTP---PPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPP----PPLPPPPPPAM 1509 Score = 62.4 bits (150), Expect = 1e-09 Identities = 29/66 (43%), Positives = 33/66 (50%), Gaps = 7/66 (10%) Query: 505 SPPPAPIYTPPPPAPHCPPPPP-------SAPTPPIPSPPSTLPPPPQAPPPNRAPPPSR 557 +P P P PPPP P P PPP S P PP+P PP P P PPP A P + Sbjct: 1466 TPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAA 1525 Query: 558 PPPRPS 563 PP P+ Sbjct: 1526 PPEEPA 1531 Score = 62.0 bits (149), Expect = 1e-09 Identities = 32/79 (40%), Positives = 38/79 (48%), Gaps = 13/79 (16%) Query: 497 LNNAYHTSSPPPAPIYTPPPPAPH-------CPPPPPSAPTPPIPSPPSTLPPPPQAPPP 549 L +A +P P + PPP P PPPPP P P +PSPP + P P +PPP Sbjct: 1439 LPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPP 1498 Query: 550 NRAPP------PSRPPPRP 562 PP PS PPP P Sbjct: 1499 PPLPPPPPPAMPSPPPPPP 1517 Score = 60.1 bits (144), Expect = 5e-09 Identities = 30/61 (49%), Positives = 31/61 (50%), Gaps = 5/61 (8%) Query: 506 PPPAPIYTPPPP----APHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPPR 561 PPP P PPP P PPPPP P PP P+ PS PPPP A P APP P Sbjct: 1476 PPPQPALPSPPPLVAPTPSSPPPPP-LPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPS 1534 Query: 562 P 562 P Sbjct: 1535 P 1535 Score = 57.0 bits (136), Expect = 4e-08 Identities = 29/64 (45%), Positives = 33/64 (51%), Gaps = 8/64 (12%) Query: 505 SPPP----APIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLP--PPPQAPPPNRAPPPSRP 558 SPPP P PPPP P PPPPP+ P+PP P PP+ P PP+ P P P Sbjct: 1484 SPPPLVAPTPSSPPPPPLP--PPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELP 1541 Query: 559 PPRP 562 RP Sbjct: 1542 DTRP 1545 Score = 52.0 bits (123), Expect = 1e-06 Identities = 31/81 (38%), Positives = 34/81 (41%), Gaps = 12/81 (14%) Query: 496 PLNNAYHTSSPP-----PAPIYTPPPPAPHCP-------PPPPSAPTPPIPSPPSTLPPP 543 PL TS+P PA PPP P P P PP P P+PP P Sbjct: 1409 PLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQ 1468 Query: 544 PQAPPPNRAPPPSRPPPRPSV 564 PQ PPP P P+ P P P V Sbjct: 1469 PQPPPPPPPPQPALPSPPPLV 1489 Score = 42.0 bits (97), Expect = 0.001 Identities = 25/64 (39%), Positives = 28/64 (43%), Gaps = 12/64 (18%) Query: 507 PPAPIYTPPPPAP-------HCPPPPPSAPTPPIPS-PPSTLPPPPQAPPPNRAPPPSRP 558 P P+ PPPP H P P PSA + P+T PQ PPP PP P Sbjct: 788 PDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPP----PPPPP 843 Query: 559 PPRP 562 PP P Sbjct: 844 PPMP 847 Score = 39.7 bits (91), Expect = 0.007 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 4/78 (5%) Query: 487 VKNNQPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQA 546 V+ + AK P++ ++ PP AP PPP P P S PP +P + +P PP Sbjct: 1674 VRRSGQAKNPVSAGGSSAPPPKAPA---PPPKPETPEKTTS-EKPPEQTPETAMPEPPAP 1729 Query: 547 PPPNRAPPPSRPPPRPSV 564 P+ P + + V Sbjct: 1730 EKPSLLRPVEKEKEKEKV 1747 Score = 33.1 bits (74), Expect = 0.69 Identities = 22/70 (31%), Positives = 25/70 (35%), Gaps = 11/70 (15%) Query: 502 HTSSPPPAP----IYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPP-------PPQAPPPN 550 H SP P+ ++ P P PP P PP P P L P AP P Sbjct: 808 HAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPR 867 Query: 551 RAPPPSRPPP 560 P S PP Sbjct: 868 LRPEESLDPP 877 Score = 32.3 bits (72), Expect = 1.2 Identities = 26/80 (32%), Positives = 29/80 (36%), Gaps = 39/80 (48%) Query: 522 PPPPPSA----PTPPI-------PSPPSTLPPPP---------QAPPPNRA--------- 552 PPPPP+A PTP P P LPPPP AP P+ + Sbjct: 765 PPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLL 824 Query: 553 ----------PPPSRPPPRP 562 PPP PPP P Sbjct: 825 EPATRDGAPQPPPPPPPPPP 844 Score = 32.3 bits (72), Expect = 1.2 Identities = 24/75 (32%), Positives = 25/75 (33%), Gaps = 22/75 (29%) Query: 506 PPPAPIYTPPPPA------------------PHCPPPPPSA----PTPPIPSPPSTLPPP 543 PP P Y P P P+ PP PS P I S P PP Sbjct: 981 PPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPP 1040 Query: 544 PQAPPPNRAPPPSRP 558 P PPP P S P Sbjct: 1041 PPPPPPPPPAPASEP 1055 Score = 31.2 bits (69), Expect = 2.6 Identities = 26/89 (29%), Positives = 30/89 (33%), Gaps = 37/89 (41%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAPT-------------------PPIPSPPSTLPPPPQA 546 P P Y P PP P PPPP PT P + + P P Sbjct: 221 PAQTPPYRPGPPDP--PPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGP--- 275 Query: 547 PPPNRA-------------PPPSRPPPRP 562 PPP RA P ++PPP P Sbjct: 276 PPPERALPRQDTVIKHYQRPASAQPPPPP 304 Score = 31.2 bits (69), Expect = 2.6 Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 5/62 (8%) Query: 502 HTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPI--PSPPSTLPPPPQAPPPNRAPPPSRPP 559 H ++PPP P PPPP P P T PI + P L R PP + P Sbjct: 1035 HQAAPPPPP---PPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTP 1091 Query: 560 PR 561 + Sbjct: 1092 KK 1093 Score = 30.4 bits (67), Expect = 4.5 Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 5/43 (11%) Query: 522 PPPPPSAPTPPIPSPPSTLPPPPQA----PPPNRAPPPSRPPP 560 PP + TPP+ SPP ++PP A P P P PPP Sbjct: 1296 PPLYQAGLTPPL-SPPKSVPPSVPARGLQPQPPATPAVPHPPP 1337 Score = 29.6 bits (65), Expect = 7.7 Identities = 17/54 (31%), Positives = 22/54 (40%), Gaps = 4/54 (7%) Query: 490 NQPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPP 543 N+P + P ++ P I + P A PPPPP P P P L P Sbjct: 1013 NKPPELPST----VNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSP 1062 >gi|56549694 enabled homolog isoform a [Homo sapiens] Length = 591 Score = 66.2 bits (160), Expect = 7e-11 Identities = 33/76 (43%), Positives = 38/76 (50%), Gaps = 3/76 (3%) Query: 490 NQPAKYPLNNAYHTS--SPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAP 547 +QPA+ P +PPP P P P PPP P PP P P + PPPP P Sbjct: 295 SQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPP 354 Query: 548 P-PNRAPPPSRPPPRP 562 P PN+ PPP PPP P Sbjct: 355 PLPNQVPPPPPPPPAP 370 Score = 53.9 bits (128), Expect = 4e-07 Identities = 26/57 (45%), Positives = 30/57 (52%), Gaps = 1/57 (1%) Query: 492 PAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPP 548 P P A + + PP P PPPP P PPPP P PP+P+ PPPP APP Sbjct: 316 PPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPP-PPPPPLPNQVPPPPPPPPAPP 371 Score = 50.4 bits (119), Expect = 4e-06 Identities = 33/85 (38%), Positives = 37/85 (43%), Gaps = 19/85 (22%) Query: 496 PLNNAYHTSSPPPAPIYTPPPPA-----------PHCPPPPPSAPTPPIPSPPST-LPPP 543 PLN+ SS + PA P PPPPP P PP P+ S LPPP Sbjct: 276 PLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPP--PLPPGPAQASVALPPP 333 Query: 544 PQAPPP-----NRAPPPSRPPPRPS 563 P PPP PPP PPP P+ Sbjct: 334 PGPPPPPPLPSTGPPPPPPPPPLPN 358 Score = 39.7 bits (91), Expect = 0.007 Identities = 18/37 (48%), Positives = 23/37 (62%), Gaps = 5/37 (13%) Query: 503 TSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPST 539 ++ PPP P PPPP P+ PPPP P PP P P++ Sbjct: 344 STGPPPPP---PPPPLPNQVPPPP--PPPPAPPLPAS 375 >gi|39930375 enabled homolog isoform b [Homo sapiens] Length = 570 Score = 66.2 bits (160), Expect = 7e-11 Identities = 33/76 (43%), Positives = 38/76 (50%), Gaps = 3/76 (3%) Query: 490 NQPAKYPLNNAYHTS--SPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAP 547 +QPA+ P +PPP P P P PPP P PP P P + PPPP P Sbjct: 295 SQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPP 354 Query: 548 P-PNRAPPPSRPPPRP 562 P PN+ PPP PPP P Sbjct: 355 PLPNQVPPPPPPPPAP 370 Score = 53.9 bits (128), Expect = 4e-07 Identities = 26/57 (45%), Positives = 30/57 (52%), Gaps = 1/57 (1%) Query: 492 PAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPP 548 P P A + + PP P PPPP P PPPP P PP+P+ PPPP APP Sbjct: 316 PPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPP-PPPPPLPNQVPPPPPPPPAPP 371 Score = 50.4 bits (119), Expect = 4e-06 Identities = 33/85 (38%), Positives = 37/85 (43%), Gaps = 19/85 (22%) Query: 496 PLNNAYHTSSPPPAPIYTPPPPA-----------PHCPPPPPSAPTPPIPSPPST-LPPP 543 PLN+ SS + PA P PPPPP P PP P+ S LPPP Sbjct: 276 PLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPP--PLPPGPAQASVALPPP 333 Query: 544 PQAPPP-----NRAPPPSRPPPRPS 563 P PPP PPP PPP P+ Sbjct: 334 PGPPPPPPLPSTGPPPPPPPPPLPN 358 Score = 39.7 bits (91), Expect = 0.007 Identities = 18/37 (48%), Positives = 23/37 (62%), Gaps = 5/37 (13%) Query: 503 TSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPST 539 ++ PPP P PPPP P+ PPPP P PP P P++ Sbjct: 344 STGPPPPP---PPPPLPNQVPPPP--PPPPAPPLPAS 375 >gi|126090663 zinc finger homeodomain 4 [Homo sapiens] Length = 3571 Score = 66.2 bits (160), Expect = 7e-11 Identities = 33/77 (42%), Positives = 41/77 (53%), Gaps = 15/77 (19%) Query: 495 YPLNNAYHTSSPPPAPIYTPPPPAPHCPPPP--------PSAPTPPIPSPPSTLPPPPQA 546 YP++ + + PPP P PPP P PP P P+ + P+ +PP T PPPP Sbjct: 1948 YPISPSSPETPPPPPP----PPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPP 2003 Query: 547 PPPNRAPPPSRPPPRPS 563 PPP PPP PPP PS Sbjct: 2004 PPP---PPPPPPPPPPS 2017 Score = 57.0 bits (136), Expect = 4e-08 Identities = 28/62 (45%), Positives = 32/62 (51%), Gaps = 10/62 (16%) Query: 511 IYTPPPPAPHC-PPPPPSAPTPPIPSPPSTLPP---------PPQAPPPNRAPPPSRPPP 560 +Y P +P PPPPP P PP P PS++ P P QAPPP PPP PPP Sbjct: 1947 LYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPP 2006 Query: 561 RP 562 P Sbjct: 2007 PP 2008 Score = 49.3 bits (116), Expect = 9e-06 Identities = 32/92 (34%), Positives = 37/92 (40%), Gaps = 24/92 (26%) Query: 473 PQPGDTGRCINFTRVKNNQPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPP 532 PQP G P K P + +PPP P PPPP P PPPPP P+ P Sbjct: 1972 PQPSSMG------------PVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPSAP 2019 Query: 533 ----------IPSPPSTLPPPPQAP--PPNRA 552 +P PS + P Q P PP A Sbjct: 2020 PQVQLPVSLDLPLFPSIMMQPVQHPALPPQLA 2051 Score = 36.2 bits (82), Expect = 0.082 Identities = 16/37 (43%), Positives = 19/37 (51%) Query: 492 PAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSA 528 P + A SS P P+ PPP P PPPPPS+ Sbjct: 3094 PTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPPSS 3130 Score = 35.8 bits (81), Expect = 0.11 Identities = 23/70 (32%), Positives = 25/70 (35%), Gaps = 15/70 (21%) Query: 505 SPPPAPIYTPPPPAPHCPPPPPSAPTPPI---------------PSPPSTLPPPPQAPPP 549 SP P P T P P P S P+PP P ST P PQ PP Sbjct: 2349 SPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPP 2408 Query: 550 NRAPPPSRPP 559 + RPP Sbjct: 2409 KQPQLIGRPP 2418 Score = 33.9 bits (76), Expect = 0.41 Identities = 21/55 (38%), Positives = 27/55 (49%), Gaps = 3/55 (5%) Query: 495 YPLNNAYHTSSPPPAPIYTPPPPAPHCPPPP-PSAPTPPIPSPPSTLPPPPQAPP 548 +P N+ +T +PP A + P A P SAPT P+ P PPPP PP Sbjct: 3076 FPQNS--NTLTPPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPP 3128 Score = 33.9 bits (76), Expect = 0.41 Identities = 20/58 (34%), Positives = 24/58 (41%), Gaps = 4/58 (6%) Query: 503 TSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPP 560 TSSP + P P PPPPP PP P PPS+ Q N+ + P Sbjct: 3098 TSSPALSLSSAPTKPLLQTPPPPP----PPPPPPPSSSLSGQQTEQQNKESEKKQTKP 3151 Score = 32.0 bits (71), Expect = 1.5 Identities = 20/74 (27%), Positives = 27/74 (36%), Gaps = 3/74 (4%) Query: 488 KNNQPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTP---PIPSPPSTLPPPP 544 K + +YP + PP+ P P PP A T P P PP Sbjct: 2356 KTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIG 2415 Query: 545 QAPPPNRAPPPSRP 558 + P ++ P PS P Sbjct: 2416 RPPSASQTPVPSSP 2429 Score = 31.6 bits (70), Expect = 2.0 Identities = 26/87 (29%), Positives = 31/87 (35%), Gaps = 16/87 (18%) Query: 493 AKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPP----PPSAPTPPIPSPP----------- 537 AK A + S P+ P P P P P P PSPP Sbjct: 2328 AKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLA 2387 Query: 538 STLPPPPQAPPPNRAPPPSRPPPRPSV 564 ST PPQA P P +PP +P + Sbjct: 2388 STSSDPPQASTAQPQPQP-QPPKQPQL 2413 Score = 30.8 bits (68), Expect = 3.4 Identities = 17/43 (39%), Positives = 18/43 (41%), Gaps = 5/43 (11%) Query: 525 PPSA-----PTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPPRP 562 PP A PT SP +L P P PPP PPP P Sbjct: 3085 PPGAGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPP 3127 >gi|55741677 SET domain containing 1A [Homo sapiens] Length = 1707 Score = 64.7 bits (156), Expect = 2e-10 Identities = 33/66 (50%), Positives = 36/66 (54%), Gaps = 8/66 (12%) Query: 505 SPPPAPI--YTPPPPAPHCPPPPPSAPTPPIPSPPST----LPPPPQAPPPNRAPPPSRP 558 SPPPAP PPPP P PPPPP + P+ PP LPP P PPP PPP P Sbjct: 593 SPPPAPTPPQQPPPPPPPPPPPPPYLASLPLGYPPHQPAYLLPPRPDGPPPPEYPPP--P 650 Query: 559 PPRPSV 564 PP P + Sbjct: 651 PPPPHI 656 Score = 45.4 bits (106), Expect = 1e-04 Identities = 33/95 (34%), Positives = 36/95 (37%), Gaps = 21/95 (22%) Query: 490 NQPAKYPLNNAY--HTSSPPPAPIYTPPPPAPHCP--------------PPPPSAPTPPI 533 N PA Y N Y HTS PP PP AP PP PS PT Sbjct: 365 NYPAYYESWNRYQRHTSYPPRRATREEPPGAPFAENTAERFPPSYTSYLPPEPSRPTDQD 424 Query: 534 PSPPSTLPPPPQAPPP-----NRAPPPSRPPPRPS 563 PP++ PPP+ P P P P R R S Sbjct: 425 YRPPASEAPPPEPPEPGGGGGGGGPSPEREEVRTS 459 Score = 44.7 bits (104), Expect = 2e-04 Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 21/83 (25%) Query: 496 PLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSP---PSTLPPPPQAPPPNR- 551 PL + + P P PP AP PP PP+ P P P P PS+ P P PPP + Sbjct: 1107 PLPEQEASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSS--PIPLLPPPKKR 1164 Query: 552 ---------------APPPSRPP 559 PPP+ PP Sbjct: 1165 RKTVSFSAIEVVPAPEPPPATPP 1187 Score = 42.4 bits (98), Expect = 0.001 Identities = 23/66 (34%), Positives = 29/66 (43%), Gaps = 2/66 (3%) Query: 500 AYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPP--PSR 557 A ++SPPP + P P P P A +P P P P A P +PP P R Sbjct: 1073 ALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLR 1132 Query: 558 PPPRPS 563 PP P+ Sbjct: 1133 PPEPPA 1138 Score = 41.6 bits (96), Expect = 0.002 Identities = 23/68 (33%), Positives = 25/68 (36%), Gaps = 11/68 (16%) Query: 506 PPPAPIYTPPP-----------PAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPP 554 P PAP+ P P P P P+ PT P PP P A PP AP Sbjct: 1087 PTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPR 1146 Query: 555 PSRPPPRP 562 P P P Sbjct: 1147 PDERPSSP 1154 Score = 38.1 bits (87), Expect = 0.022 Identities = 24/60 (40%), Positives = 30/60 (50%), Gaps = 6/60 (10%) Query: 505 SPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNR---APPPSRPPPR 561 +P P +P PA PPSAP P P PP+ PP AP P+ +P P PPP+ Sbjct: 1106 TPLPEQEASPARPAGPTEESPPSAPLRP-PEPPA--GPPAPAPRPDERPSSPIPLLPPPK 1162 Score = 37.0 bits (84), Expect = 0.048 Identities = 49/229 (21%), Positives = 79/229 (34%), Gaps = 47/229 (20%) Query: 354 VPPPPAEESEEEDDDGLPKKKWPTVDASYYGGRGVGG---IKRMEVRWGEKGSTEEGAKL 410 +PP P+ +++ D P + P + GG G GG +R EVR + Sbjct: 413 LPPEPSRPTDQ--DYRPPASEAPPPEPPEPGGGGGGGGPSPEREEVRTSPR--------- 461 Query: 411 EKAKNARVKMPEQEYEFPEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSV 470 A AR P PE N S P +S + +++ +LL++ + S Sbjct: 462 -PASPARSGSPA-----PETTN-------ESVPFAQHSSLDSRIE---MLLKEQRSKFSF 505 Query: 471 MRPQPGDTGRCINFTRVKNNQPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPT 530 + + + + ++ P + + +PPPAP P + + Sbjct: 506 LASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFEDVAPTGSGEPGATRES 565 Query: 531 PPIPSPPSTLP-----------------PPPQAPPPNRAPPPSRPPPRP 562 P P PPP PP + PPP PPP P Sbjct: 566 PKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQQPPPPPPPPPPP 614 Score = 36.6 bits (83), Expect = 0.063 Identities = 27/80 (33%), Positives = 31/80 (38%), Gaps = 14/80 (17%) Query: 492 PAKYPLNNAYHTSSPP---PAPIYTPPPPAPHCPPPPPSAPT------PPIPSPPSTLPP 542 P PL + PP P P P P P PPP T +P+P P Sbjct: 1126 PPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAP----EP 1181 Query: 543 PPQAPPPNRAP-PPSRPPPR 561 PP PP + P P SR PR Sbjct: 1182 PPATPPQAKFPGPASRKAPR 1201 Score = 29.6 bits (65), Expect = 7.7 Identities = 16/54 (29%), Positives = 21/54 (38%), Gaps = 1/54 (1%) Query: 498 NNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNR 551 N A PPAP PP P P P S+P + P + + P P + Sbjct: 1301 NYALAVKPTPPAPALRPPEPVP-APAALFSSPADEVLEAPEVVVAEAEEPKPQQ 1353 >gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sapiens] Length = 505 Score = 63.9 bits (154), Expect = 4e-10 Identities = 34/70 (48%), Positives = 37/70 (52%), Gaps = 10/70 (14%) Query: 503 TSSPPPAP------IYTPPPPAPHCPPPPP----SAPTPPIPSPPSTLPPPPQAPPPNRA 552 T++PPP P PPPP PPPPP SAP+ P P PPS L P APPP Sbjct: 319 TAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPP 378 Query: 553 PPPSRPPPRP 562 PPP PP P Sbjct: 379 PPPPPGPPPP 388 Score = 60.1 bits (144), Expect = 5e-09 Identities = 35/70 (50%), Positives = 37/70 (52%), Gaps = 15/70 (21%) Query: 506 PPPAPIYTPPPPAPH----CPPPPPS-----APTPPIPSPPSTLPPPPQAPPPNR---AP 553 PPP P + PPP P PPPPPS AP PP PS PS PP PPPNR P Sbjct: 290 PPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPP---PPPNRMYPPP 346 Query: 554 PPSRPPPRPS 563 PP+ P PS Sbjct: 347 PPALPSSAPS 356 Score = 59.7 bits (143), Expect = 7e-09 Identities = 35/83 (42%), Positives = 43/83 (51%), Gaps = 15/83 (18%) Query: 497 LNNAYHTSSPPPAPIYT----PPPPAPHC--PPPPPS----APTPPIPSPPSTLPPPPQA 546 + N +PPP P PPPP PH PPPPP+ AP PP P+ PPPP Sbjct: 268 VKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPP 327 Query: 547 PPPNRA---PPPSR--PPPRPSV 564 P+ A PPP+R PPP P++ Sbjct: 328 SRPSVAVPPPPPNRMYPPPPPAL 350 Score = 59.3 bits (142), Expect = 9e-09 Identities = 36/88 (40%), Positives = 39/88 (44%), Gaps = 27/88 (30%) Query: 502 HTSSPPPAPIY---TPPPPAPHCP-----PPPPSAPTPPIPSPPST--LPPPPQA----- 546 H S PPP P PPPP P PPPPS P+ +P PP PPPP A Sbjct: 295 HNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSA 354 Query: 547 ------PPPN------RAPPPSRPPPRP 562 PPP+ APPP PPP P Sbjct: 355 PSGPPPPPPSVLGVGPVAPPPPPPPPPP 382 Score = 59.3 bits (142), Expect = 9e-09 Identities = 31/72 (43%), Positives = 34/72 (47%), Gaps = 7/72 (9%) Query: 492 PAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPS-----PPSTLPPPPQA 546 P P + PPP +Y PPPPA P PS P PP PS P + PPPP Sbjct: 323 PPPPPSRPSVAVPPPPPNRMYPPPPPA--LPSSAPSGPPPPPPSVLGVGPVAPPPPPPPP 380 Query: 547 PPPNRAPPPSRP 558 PPP PPP P Sbjct: 381 PPPGPPPPPGLP 392 Score = 57.4 bits (137), Expect = 3e-08 Identities = 33/80 (41%), Positives = 37/80 (46%), Gaps = 21/80 (26%) Query: 506 PPP--APIYTPPPPAPH-----CPPPPPSA----PTPPIPSPPSTLPPPP---------- 544 PPP AP PPPP P PPPPP+ P P +PS + PPPP Sbjct: 312 PPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPV 371 Query: 545 QAPPPNRAPPPSRPPPRPSV 564 PPP PPP PPP P + Sbjct: 372 APPPPPPPPPPPGPPPPPGL 391 Score = 57.0 bits (136), Expect = 4e-08 Identities = 37/87 (42%), Positives = 39/87 (44%), Gaps = 30/87 (34%) Query: 505 SPPPAPIYTP---PPPAP------HCPPPPP-------------SAPTPPIPSPPSTL-- 540 +PPP P P PPP P PPPPP SAP+ P P PPS L Sbjct: 309 APPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGV 368 Query: 541 ----PPPPQAPPPNRAPPPSRPPPRPS 563 PPPP PPP PPP PP PS Sbjct: 369 GPVAPPPPPPPPPPPGPPP--PPGLPS 393 >gi|150417989 cyclin K isoform 1 [Homo sapiens] Length = 580 Score = 63.9 bits (154), Expect = 4e-10 Identities = 36/83 (43%), Positives = 40/83 (48%), Gaps = 16/83 (19%) Query: 492 PAKYPLNNAYHTSSPPPAPIYTPPPPA----PHCPPPPPSAPTPP------IPSPPSTLP 541 PA P + + +PPP P+ PPPPA P PPP P P PP P PP LP Sbjct: 468 PAHLPYHPHVYPPNPPPPPV--PPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLP 525 Query: 542 P----PPQAPPPNRAPPPSRPPP 560 P PP PP PP S PPP Sbjct: 526 PTHAVPPHPPPGLGLPPASYPPP 548 Score = 63.5 bits (153), Expect = 5e-10 Identities = 28/54 (51%), Positives = 30/54 (55%) Query: 511 IYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPPRPSV 564 +Y P PP P PPPP S P P IP P PPPP PN PPP R PP +V Sbjct: 477 VYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAV 530 Score = 62.8 bits (151), Expect = 8e-10 Identities = 36/82 (43%), Positives = 40/82 (48%), Gaps = 14/82 (17%) Query: 492 PAKYPLNNAYHTSSPPPAPIYTPPPPA--PHCPPPPPSAP----TPPIPSPPSTLPP--- 542 PA +P + PPP P Y PPPP P+ PPPPP P PP P P LPP Sbjct: 491 PASFP-----PPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASY 545 Query: 543 PPQAPPPNRAPPPSRPPPRPSV 564 PP A PP PP P P P + Sbjct: 546 PPPAVPPGGQPPVPPPIPPPGM 567 Score = 60.5 bits (145), Expect = 4e-09 Identities = 29/63 (46%), Positives = 30/63 (47%), Gaps = 9/63 (14%) Query: 506 PPPAPIYTP--PPPAPHCPP-------PPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPS 556 PPP P Y P PPP P PP PPP PP PP +PP Q P P PPP Sbjct: 507 PPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPG 566 Query: 557 RPP 559 PP Sbjct: 567 MPP 569 Score = 52.4 bits (124), Expect = 1e-06 Identities = 34/103 (33%), Positives = 39/103 (37%), Gaps = 47/103 (45%) Query: 506 PP--PAPIYTPPPPAPHCPPPPPSA---------------------------------PT 530 PP PAP++ PPP PH PPPPP + Sbjct: 403 PPAHPAPVHQ-PPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGAL 461 Query: 531 PPIPSPPSTL-----------PPPPQAPPPNRAPPPSRPPPRP 562 PP PP+ L PPPP PPP PPP+ PPP P Sbjct: 462 PPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTP 504 Score = 51.6 bits (122), Expect = 2e-06 Identities = 25/52 (48%), Positives = 30/52 (57%), Gaps = 4/52 (7%) Query: 510 PIYTPPPPAPHCPPP-PPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPP 560 P Y PP P+ P PP+ P PP+P PP++ PPP PPP PP PPP Sbjct: 463 PAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPA-IPPPTPGYPP--PPP 511 Score = 45.1 bits (105), Expect = 2e-04 Identities = 30/73 (41%), Positives = 31/73 (42%), Gaps = 16/73 (21%) Query: 506 PPPAP-IYTPPPPAPHCPPPPPSAP---------TPPIPSPPSTLP----PPPQAPPPNR 551 PP P I T PP P PPP P PP P + LP PPP P P Sbjct: 352 PPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVH 411 Query: 552 APP--PSRPPPRP 562 PP P RPPP P Sbjct: 412 QPPPLPHRPPPPP 424 Score = 40.0 bits (92), Expect = 0.006 Identities = 32/106 (30%), Positives = 39/106 (36%), Gaps = 31/106 (29%) Query: 488 KNNQPAKYPLNNAYHTSSPPP---APIYTPPPPAPHCPPPPPSAPT-----PPIP---SP 536 + QPA+ P + SSP A + +P PPPP P PP+P P Sbjct: 312 QQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPP 371 Query: 537 PSTLPP---------PP-----------QAPPPNRAPPPSRPPPRP 562 P PP PP Q PPP P +PPP P Sbjct: 372 PDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLP 417 Score = 34.3 bits (77), Expect = 0.31 Identities = 22/59 (37%), Positives = 24/59 (40%), Gaps = 5/59 (8%) Query: 490 NQPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPP 548 N P P H P P P PPA + PP P PP+P P PPP PP Sbjct: 516 NFPPPPPRLPPTHAVPPHPPPG-LGLPPASYPPPAVPPGGQPPVPPP----IPPPGMPP 569 Score = 33.5 bits (75), Expect = 0.53 Identities = 18/53 (33%), Positives = 21/53 (39%) Query: 492 PAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPP 544 P + P A + PP P+ P PPP AP P P PPPP Sbjct: 372 PDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPP 424 Score = 31.2 bits (69), Expect = 2.6 Identities = 23/63 (36%), Positives = 27/63 (42%), Gaps = 14/63 (22%) Query: 515 PPPAPHCPPPPPSA-PTPPIP----SPPSTLPPP-------PQAPPPNRAP--PPSRPPP 560 P PH PPS PTP +P S PS P PQ P + P P +P P Sbjct: 266 PHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSP 325 Query: 561 RPS 563 +PS Sbjct: 326 QPS 328 Score = 30.0 bits (66), Expect = 5.9 Identities = 28/101 (27%), Positives = 36/101 (35%), Gaps = 36/101 (35%) Query: 486 RVKNNQPAKYPLNNAYHTSSPPPAPIYTPP--PPAPHCPPPPPSAPTPPIPSPPSTL--- 540 +V+ +QP++ SS P P P P P P P+P PS P + Sbjct: 287 QVQQSQPSQ---------SSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQ-PSSPRQVKRA 336 Query: 541 -------------PPPPQAPP--------PNRAPPPSRPPP 560 PPPP+ P P PPP R PP Sbjct: 337 VVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPP 377 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 63.5 bits (153), Expect = 5e-10 Identities = 31/60 (51%), Positives = 32/60 (53%), Gaps = 6/60 (10%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPS---TLPPPPQAPPPNRAPPPSRPPPRP 562 PPP P PPPP P P PPP P PP P P T+PPPP PP PPP PP P Sbjct: 691 PPPPP---PPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPP 747 Score = 59.7 bits (143), Expect = 7e-09 Identities = 29/55 (52%), Positives = 31/55 (56%), Gaps = 2/55 (3%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPP-PSRPP 559 PPP P + PPP P PPPPP A P + PP LP PP PPP PP P PP Sbjct: 697 PPPQPGFPMPPPLPPPPPPPPPA-HPAVTVPPPPLPAPPGVPPPPILPPLPPFPP 750 Score = 52.8 bits (125), Expect = 8e-07 Identities = 29/64 (45%), Positives = 33/64 (51%), Gaps = 7/64 (10%) Query: 505 SPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQA----PPPNRAPPPSRPPP 560 +P A + P AP P PPP PP+P PP PPPPQ PPP PPP PP Sbjct: 663 TPGAAAVAAPSVLAPTLPLPPPPG-FPPLPPPPP--PPPPQPGFPMPPPLPPPPPPPPPA 719 Query: 561 RPSV 564 P+V Sbjct: 720 HPAV 723 Score = 52.0 bits (123), Expect = 1e-06 Identities = 26/57 (45%), Positives = 27/57 (47%), Gaps = 2/57 (3%) Query: 509 APIYTPPPPAPHCPPPPPSAPTPPIPS--PPSTLPPPPQAPPPNRAPPPSRPPPRPS 563 AP PPP P PPP P PP P P LPPPP PPP PPP P+ Sbjct: 676 APTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPA 732 Score = 47.0 bits (110), Expect = 5e-05 Identities = 28/65 (43%), Positives = 32/65 (49%), Gaps = 6/65 (9%) Query: 503 TSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLP-PPPQAPPPNR----APPPSR 557 TS+ P P+ P A P APT P+P PP P PPP PPP + PPP Sbjct: 652 TSADCPKPMVVTPGAAA-VAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLP 710 Query: 558 PPPRP 562 PPP P Sbjct: 711 PPPPP 715 Score = 43.5 bits (101), Expect = 5e-04 Identities = 25/62 (40%), Positives = 28/62 (45%), Gaps = 8/62 (12%) Query: 509 APIYTPPPPAPHCPPPPPSAPTPPI-------PSPPSTLPPPPQAP-PPNRAPPPSRPPP 560 A + +P PPA PP +P P PP LP P Q P PP R P P PPP Sbjct: 1236 AMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPP 1295 Query: 561 RP 562 P Sbjct: 1296 EP 1297 Score = 39.7 bits (91), Expect = 0.007 Identities = 21/54 (38%), Positives = 23/54 (42%), Gaps = 2/54 (3%) Query: 507 PPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAP--PPSRP 558 P P+ P P P PPP P P P P P +T P PP A PP P Sbjct: 1268 PEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTP 1321 Score = 39.3 bits (90), Expect = 0.010 Identities = 22/56 (39%), Positives = 26/56 (46%), Gaps = 1/56 (1%) Query: 507 PPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPPRP 562 P API + P P P +A P P+ PPP PP PPP PPP+P Sbjct: 647 PSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPP-PPPQP 701 Score = 37.0 bits (84), Expect = 0.048 Identities = 22/56 (39%), Positives = 24/56 (42%), Gaps = 4/56 (7%) Query: 508 PAPIYTPPPPAPHCPPPPP-SAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPPRP 562 P TP P+ H P IP+PP LPP P PPP PPP P P Sbjct: 1510 PGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPP---PPPVEPTKLP 1562 Score = 36.6 bits (83), Expect = 0.063 Identities = 22/58 (37%), Positives = 24/58 (41%), Gaps = 4/58 (6%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPP----NRAPPPSRPP 559 PP +P P P PP P P P P PP P +PPP A PS PP Sbjct: 1252 PPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPP 1309 Score = 35.8 bits (81), Expect = 0.11 Identities = 21/61 (34%), Positives = 25/61 (40%), Gaps = 13/61 (21%) Query: 515 PPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPP------------NRAP-PPSRPPPR 561 PPPA P P + P +P + PPPP+ P RAP PP PP Sbjct: 382 PPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAE 441 Query: 562 P 562 P Sbjct: 442 P 442 Score = 35.0 bits (79), Expect = 0.18 Identities = 31/105 (29%), Positives = 32/105 (30%), Gaps = 46/105 (43%) Query: 505 SPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTL----------------------PP 542 +P P P P P A CPPP P P SPPS L P Sbjct: 1453 APTPLPPLLPAPLAS-CPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPG 1511 Query: 543 PPQ-----------------------APPPNRAPPPSRPPPRPSV 564 PQ APPP P P PPP P V Sbjct: 1512 QPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPV 1556 Score = 35.0 bits (79), Expect = 0.18 Identities = 21/53 (39%), Positives = 24/53 (45%), Gaps = 11/53 (20%) Query: 499 NAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTP-PIPS-----PPSTLPPPPQ 545 NA + PPP P PPP PPPPP PT P P +PP P+ Sbjct: 1533 NAGIPAPPPPLPPQPPPP-----PPPPPVEPTKLPFKELDNQWPSEAIPPGPR 1580 Score = 33.9 bits (76), Expect = 0.41 Identities = 28/92 (30%), Positives = 34/92 (36%), Gaps = 24/92 (26%) Query: 496 PLNNAYHTSSPPPAPIYTPPP-----------PAPHCPPPP--PSAPTP----------P 532 P ++A +PPPA TP P P H PPPP P+A Sbjct: 372 PQDSATFAHTPPPAQA-TPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRR 430 Query: 533 IPSPPSTLPPPPQAPPPNRAPPPSRPPPRPSV 564 P+PP P P A PP PP S+ Sbjct: 431 APAPPPLPPAEPLAKEKPGTPPGPPPPDTNSM 462 Score = 33.1 bits (74), Expect = 0.69 Identities = 22/69 (31%), Positives = 25/69 (36%), Gaps = 12/69 (17%) Query: 506 PPPAPIYTPPPPAPH--------CPPPPPSAPTPPI--PSPPSTLPPPPQAPPPNRAPPP 555 PP + PP +P P PP P+ P PP P PP PP Sbjct: 1243 PPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDA 1302 Query: 556 SRP--PPRP 562 S P PP P Sbjct: 1303 SHPSVPPEP 1311 Score = 32.7 bits (73), Expect = 0.91 Identities = 16/42 (38%), Positives = 18/42 (42%), Gaps = 3/42 (7%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAP 547 PPP P P PP+P P A P +P P PP P Sbjct: 1283 PPPRP---PRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTP 1321 Score = 32.7 bits (73), Expect = 0.91 Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 6/58 (10%) Query: 503 TSSPPPAPIYTPPPPA-PHCPPPPPSAPTPP---IPSPPSTLPPPPQAPP--PNRAPP 554 T P P P+ P P A P APTP +P+P ++ PPP + P P R+PP Sbjct: 1427 TGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPP 1484 Score = 32.7 bits (73), Expect = 0.91 Identities = 18/43 (41%), Positives = 20/43 (46%), Gaps = 2/43 (4%) Query: 517 PAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPP 559 PAP PPP P P PP P PP P N+ P + PP Sbjct: 1537 PAP--PPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPP 1577 Score = 31.6 bits (70), Expect = 2.0 Identities = 20/71 (28%), Positives = 23/71 (32%), Gaps = 17/71 (23%) Query: 505 SPPPAPI--YTPPPPAP---------------HCPPPPPSAPTPPIPSPPSTLPPPPQAP 547 SP P+ + PPP P P PPP P P+ PP P P Sbjct: 398 SPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPP 457 Query: 548 PPNRAPPPSRP 558 N RP Sbjct: 458 DTNSMELGGRP 468 Score = 31.6 bits (70), Expect = 2.0 Identities = 21/59 (35%), Positives = 24/59 (40%), Gaps = 9/59 (15%) Query: 473 PQPGDTGRCINFTRVKNNQPAKYPLNNAYHTSSPPPAPIYTPP--PPAPHCPPPPPSAP 529 PQPG F P P A+ + PP P+ PP PP P PP PP P Sbjct: 699 PQPG-------FPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPP 750 >gi|33356148 formin-like 1 [Homo sapiens] Length = 1100 Score = 63.2 bits (152), Expect = 6e-10 Identities = 34/80 (42%), Positives = 35/80 (43%), Gaps = 9/80 (11%) Query: 492 PAKYPLNNAYHTSSPP----PAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAP 547 PA P A PP P+P PP P PP P S PP P P LPPPP P Sbjct: 532 PAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPP 591 Query: 548 PP-----NRAPPPSRPPPRP 562 PP PPP PPP P Sbjct: 592 PPPPGTDGPVPPPPPPPPPP 611 Score = 52.8 bits (125), Expect = 8e-07 Identities = 27/61 (44%), Positives = 29/61 (47%), Gaps = 9/61 (14%) Query: 504 SSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPP-----STLPPPPQAPPPNRAPPPSRP 558 S+PP AP P P PP P P PP P PP +PPPP PP PPP P Sbjct: 560 SAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPP----PPPGGP 615 Query: 559 P 559 P Sbjct: 616 P 616 Score = 52.8 bits (125), Expect = 8e-07 Identities = 25/57 (43%), Positives = 27/57 (47%), Gaps = 3/57 (5%) Query: 492 PAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPP 548 P PL + PP P PPPP P PPPP P+P PP PPPP PP Sbjct: 563 PQAPPLPGSPEPPPAPPLPGDLPPPPPP---PPPPPGTDGPVPPPPPPPPPPPGGPP 616 Score = 45.8 bits (107), Expect = 1e-04 Identities = 28/61 (45%), Positives = 33/61 (54%), Gaps = 6/61 (9%) Query: 507 PPAPIYTPPPP-APHCPPPPPSAPTPPIPSPPSTLPPPPQAPP--PNRAPP-PSRPPPRP 562 P P +P P AP P P +AP PP P P LP P +APP P +APP P P P P Sbjct: 519 PGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPG--LPSPQEAPPSAPPQAPPLPGSPEPPP 576 Query: 563 S 563 + Sbjct: 577 A 577 Score = 38.5 bits (88), Expect = 0.017 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 7/62 (11%) Query: 508 PAPIYTPPPPAPHCPPPPPSAPTPPI-----PSPPSTLPPPPQAP--PPNRAPPPSRPPP 560 P + TP P P +P+P + P+P + PPPP P P + PPS PP Sbjct: 505 PVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQ 564 Query: 561 RP 562 P Sbjct: 565 AP 566 Score = 37.7 bits (86), Expect = 0.028 Identities = 20/39 (51%), Positives = 20/39 (51%), Gaps = 8/39 (20%) Query: 506 PPPAPIYTPPPPAPHC----PPPPPSAPTPPIPSPPSTL 540 PPP P PPPP P PPPPP P PP PP L Sbjct: 585 PPPPP---PPPPPPGTDGPVPPPPPPPPPPP-GGPPDAL 619 Score = 37.7 bits (86), Expect = 0.028 Identities = 20/46 (43%), Positives = 22/46 (47%), Gaps = 2/46 (4%) Query: 506 PPPAPIYT--PPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPP 549 PPP P T P PP P PPPPP P + S L P +A P Sbjct: 590 PPPPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDSELGPGVKAKKP 635 Score = 36.6 bits (83), Expect = 0.063 Identities = 24/65 (36%), Positives = 27/65 (41%), Gaps = 4/65 (6%) Query: 500 AYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPP--PSR 557 A T S AP P +P P + P P PP PP P P P APP P + Sbjct: 507 AVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPP--PPLPGLPSPQEAPPSAPPQ 564 Query: 558 PPPRP 562 PP P Sbjct: 565 APPLP 569 >gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo sapiens] Length = 1188 Score = 62.8 bits (151), Expect = 8e-10 Identities = 32/82 (39%), Positives = 40/82 (48%), Gaps = 13/82 (15%) Query: 492 PAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPP---------SAPTPPIPSPPSTLPP 542 P PL + T+ PPP + PPPP PPPPP + +P IP+PP +PP Sbjct: 158 PGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPP 217 Query: 543 PPQ----APPPNRAPPPSRPPP 560 P APPP P P+ P P Sbjct: 218 APPLAFLAPPPPPVPAPAPPAP 239 Score = 54.7 bits (130), Expect = 2e-07 Identities = 30/59 (50%), Positives = 32/59 (54%), Gaps = 11/59 (18%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPP-----QAPPPNRAPPPSRPP 559 PPP P P PP PP S P+PSPPST PPPP PPP+ APPP PP Sbjct: 140 PPPPPGPAPGPPQDISEPPGGS----PLPSPPSTAPPPPPLLLEPPPPPSMAPPP--PP 192 Score = 47.0 bits (110), Expect = 5e-05 Identities = 28/70 (40%), Positives = 30/70 (42%), Gaps = 15/70 (21%) Query: 506 PPPAPIYTPP------PPAPHCPPPPPSAPTPP-----IPSPPSTLPPPPQA----PPPN 550 PPP P PP P P PP +AP PP P PPS PPPP PP+ Sbjct: 142 PPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPH 201 Query: 551 RAPPPSRPPP 560 PS P P Sbjct: 202 TLSSPSIPTP 211 Score = 45.8 bits (107), Expect = 1e-04 Identities = 26/64 (40%), Positives = 32/64 (50%), Gaps = 10/64 (15%) Query: 505 SPPPAPIYTPPPPAPHCPPP----PPSAPTPPIPS----PPSTLPPPPQAPPPNRAPPPS 556 +PPPAP PPPAP PPP PP+AP P PP+ P++ P P P+ Sbjct: 389 TPPPAPPL--PPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPN 446 Query: 557 RPPP 560 P P Sbjct: 447 PPSP 450 Score = 43.9 bits (102), Expect = 4e-04 Identities = 25/59 (42%), Positives = 27/59 (45%), Gaps = 12/59 (20%) Query: 515 PPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQA-----PP------PNRAPPPSRPPPRP 562 PPPAP PPP P P PP P P PP P A PP P + P +P P P Sbjct: 390 PPPAPPLPPPAPPLP-PPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNP 447 Score = 43.1 bits (100), Expect = 7e-04 Identities = 31/87 (35%), Positives = 39/87 (44%), Gaps = 24/87 (27%) Query: 492 PAKYPLNNAYHTSSPPPAPIYTPPPPAPHCP-------PPPPS-----------APTPPI 533 P++ PL ++H P + +Y P P CP P P A TPP Sbjct: 335 PSRLPLPPSFHIR--PASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPP- 391 Query: 534 PSPPSTLPPP-PQAPPPNRAPPPSRPP 559 P+PP LPPP P PPP PP+ PP Sbjct: 392 PAPP--LPPPAPPLPPPAPPLPPAAPP 416 Score = 40.0 bits (92), Expect = 0.006 Identities = 23/47 (48%), Positives = 25/47 (53%), Gaps = 10/47 (21%) Query: 502 HTSSPPPAPIYTPP---PPAPHC-----PPPPPSAPTPPIPSPPSTL 540 HT S P P TPP PPAP PPPP AP PP P+ P T+ Sbjct: 201 HTLSSPSIP--TPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTV 245 Score = 31.2 bits (69), Expect = 2.6 Identities = 21/71 (29%), Positives = 24/71 (33%), Gaps = 13/71 (18%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPP-------------PPQAPPPNRA 552 PP P+ PP P P P P AP P PP QA + Sbjct: 216 PPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRAS 275 Query: 553 PPPSRPPPRPS 563 PP S P+ S Sbjct: 276 PPRSPAEPKGS 286 Score = 31.2 bits (69), Expect = 2.6 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 2/56 (3%) Query: 505 SPPPAPIYTPPPPAPHCPPPPPSAPTPP--IPSPPSTLPPPPQAPPPNRAPPPSRP 558 +PPP P+ P PPAP P + PP + S + + RA PP P Sbjct: 225 APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSP 280 Score = 30.4 bits (67), Expect = 4.5 Identities = 20/60 (33%), Positives = 24/60 (40%), Gaps = 8/60 (13%) Query: 506 PPPAPIYTPPPPAPHCPPPP-------PSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRP 558 PPP P+ T P P AP+ +P PPS P P+RAP P P Sbjct: 305 PPPTPVRTSSIPVQEAQEAPRKEEGATKKAPS-RLPLPPSFHIRPASQVYPDRAPEPDCP 363 >gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo sapiens] Length = 1188 Score = 62.8 bits (151), Expect = 8e-10 Identities = 32/82 (39%), Positives = 40/82 (48%), Gaps = 13/82 (15%) Query: 492 PAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPP---------SAPTPPIPSPPSTLPP 542 P PL + T+ PPP + PPPP PPPPP + +P IP+PP +PP Sbjct: 158 PGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPP 217 Query: 543 PPQ----APPPNRAPPPSRPPP 560 P APPP P P+ P P Sbjct: 218 APPLAFLAPPPPPVPAPAPPAP 239 Score = 54.7 bits (130), Expect = 2e-07 Identities = 30/59 (50%), Positives = 32/59 (54%), Gaps = 11/59 (18%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPP-----QAPPPNRAPPPSRPP 559 PPP P P PP PP S P+PSPPST PPPP PPP+ APPP PP Sbjct: 140 PPPPPGPAPGPPQDISEPPGGS----PLPSPPSTAPPPPPLLLEPPPPPSMAPPP--PP 192 Score = 47.0 bits (110), Expect = 5e-05 Identities = 28/70 (40%), Positives = 30/70 (42%), Gaps = 15/70 (21%) Query: 506 PPPAPIYTPP------PPAPHCPPPPPSAPTPP-----IPSPPSTLPPPPQA----PPPN 550 PPP P PP P P PP +AP PP P PPS PPPP PP+ Sbjct: 142 PPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPH 201 Query: 551 RAPPPSRPPP 560 PS P P Sbjct: 202 TLSSPSIPTP 211 Score = 45.8 bits (107), Expect = 1e-04 Identities = 26/64 (40%), Positives = 32/64 (50%), Gaps = 10/64 (15%) Query: 505 SPPPAPIYTPPPPAPHCPPP----PPSAPTPPIPS----PPSTLPPPPQAPPPNRAPPPS 556 +PPPAP PPPAP PPP PP+AP P PP+ P++ P P P+ Sbjct: 389 TPPPAPPL--PPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPN 446 Query: 557 RPPP 560 P P Sbjct: 447 PPSP 450 Score = 43.9 bits (102), Expect = 4e-04 Identities = 25/59 (42%), Positives = 27/59 (45%), Gaps = 12/59 (20%) Query: 515 PPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQA-----PP------PNRAPPPSRPPPRP 562 PPPAP PPP P P PP P P PP P A PP P + P +P P P Sbjct: 390 PPPAPPLPPPAPPLP-PPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNP 447 Score = 43.1 bits (100), Expect = 7e-04 Identities = 31/87 (35%), Positives = 39/87 (44%), Gaps = 24/87 (27%) Query: 492 PAKYPLNNAYHTSSPPPAPIYTPPPPAPHCP-------PPPPS-----------APTPPI 533 P++ PL ++H P + +Y P P CP P P A TPP Sbjct: 335 PSRLPLPPSFHIR--PASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPP- 391 Query: 534 PSPPSTLPPP-PQAPPPNRAPPPSRPP 559 P+PP LPPP P PPP PP+ PP Sbjct: 392 PAPP--LPPPAPPLPPPAPPLPPAAPP 416 Score = 40.0 bits (92), Expect = 0.006 Identities = 23/47 (48%), Positives = 25/47 (53%), Gaps = 10/47 (21%) Query: 502 HTSSPPPAPIYTPP---PPAPHC-----PPPPPSAPTPPIPSPPSTL 540 HT S P P TPP PPAP PPPP AP PP P+ P T+ Sbjct: 201 HTLSSPSIP--TPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTV 245 Score = 31.2 bits (69), Expect = 2.6 Identities = 21/71 (29%), Positives = 24/71 (33%), Gaps = 13/71 (18%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPP-------------PPQAPPPNRA 552 PP P+ PP P P P P AP P PP QA + Sbjct: 216 PPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRAS 275 Query: 553 PPPSRPPPRPS 563 PP S P+ S Sbjct: 276 PPRSPAEPKGS 286 Score = 31.2 bits (69), Expect = 2.6 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 2/56 (3%) Query: 505 SPPPAPIYTPPPPAPHCPPPPPSAPTPP--IPSPPSTLPPPPQAPPPNRAPPPSRP 558 +PPP P+ P PPAP P + PP + S + + RA PP P Sbjct: 225 APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSP 280 Score = 30.4 bits (67), Expect = 4.5 Identities = 20/60 (33%), Positives = 24/60 (40%), Gaps = 8/60 (13%) Query: 506 PPPAPIYTPPPPAPHCPPPP-------PSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRP 558 PPP P+ T P P AP+ +P PPS P P+RAP P P Sbjct: 305 PPPTPVRTSSIPVQEAQEAPRKEEGATKKAPS-RLPLPPSFHIRPASQVYPDRAPEPDCP 363 >gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens] Length = 1188 Score = 62.8 bits (151), Expect = 8e-10 Identities = 32/82 (39%), Positives = 40/82 (48%), Gaps = 13/82 (15%) Query: 492 PAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPP---------SAPTPPIPSPPSTLPP 542 P PL + T+ PPP + PPPP PPPPP + +P IP+PP +PP Sbjct: 158 PGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPP 217 Query: 543 PPQ----APPPNRAPPPSRPPP 560 P APPP P P+ P P Sbjct: 218 APPLAFLAPPPPPVPAPAPPAP 239 Score = 54.7 bits (130), Expect = 2e-07 Identities = 30/59 (50%), Positives = 32/59 (54%), Gaps = 11/59 (18%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPP-----QAPPPNRAPPPSRPP 559 PPP P P PP PP S P+PSPPST PPPP PPP+ APPP PP Sbjct: 140 PPPPPGPAPGPPQDISEPPGGS----PLPSPPSTAPPPPPLLLEPPPPPSMAPPP--PP 192 Score = 47.0 bits (110), Expect = 5e-05 Identities = 28/70 (40%), Positives = 30/70 (42%), Gaps = 15/70 (21%) Query: 506 PPPAPIYTPP------PPAPHCPPPPPSAPTPP-----IPSPPSTLPPPPQA----PPPN 550 PPP P PP P P PP +AP PP P PPS PPPP PP+ Sbjct: 142 PPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPH 201 Query: 551 RAPPPSRPPP 560 PS P P Sbjct: 202 TLSSPSIPTP 211 Score = 45.8 bits (107), Expect = 1e-04 Identities = 26/64 (40%), Positives = 32/64 (50%), Gaps = 10/64 (15%) Query: 505 SPPPAPIYTPPPPAPHCPPP----PPSAPTPPIPS----PPSTLPPPPQAPPPNRAPPPS 556 +PPPAP PPPAP PPP PP+AP P PP+ P++ P P P+ Sbjct: 389 TPPPAPPL--PPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPN 446 Query: 557 RPPP 560 P P Sbjct: 447 PPSP 450 Score = 43.9 bits (102), Expect = 4e-04 Identities = 25/59 (42%), Positives = 27/59 (45%), Gaps = 12/59 (20%) Query: 515 PPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQA-----PP------PNRAPPPSRPPPRP 562 PPPAP PPP P P PP P P PP P A PP P + P +P P P Sbjct: 390 PPPAPPLPPPAPPLP-PPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNP 447 Score = 43.1 bits (100), Expect = 7e-04 Identities = 31/87 (35%), Positives = 39/87 (44%), Gaps = 24/87 (27%) Query: 492 PAKYPLNNAYHTSSPPPAPIYTPPPPAPHCP-------PPPPS-----------APTPPI 533 P++ PL ++H P + +Y P P CP P P A TPP Sbjct: 335 PSRLPLPPSFHIR--PASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPP- 391 Query: 534 PSPPSTLPPP-PQAPPPNRAPPPSRPP 559 P+PP LPPP P PPP PP+ PP Sbjct: 392 PAPP--LPPPAPPLPPPAPPLPPAAPP 416 Score = 40.0 bits (92), Expect = 0.006 Identities = 23/47 (48%), Positives = 25/47 (53%), Gaps = 10/47 (21%) Query: 502 HTSSPPPAPIYTPP---PPAPHC-----PPPPPSAPTPPIPSPPSTL 540 HT S P P TPP PPAP PPPP AP PP P+ P T+ Sbjct: 201 HTLSSPSIP--TPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTV 245 Score = 31.2 bits (69), Expect = 2.6 Identities = 21/71 (29%), Positives = 24/71 (33%), Gaps = 13/71 (18%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPP-------------PPQAPPPNRA 552 PP P+ PP P P P P AP P PP QA + Sbjct: 216 PPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRAS 275 Query: 553 PPPSRPPPRPS 563 PP S P+ S Sbjct: 276 PPRSPAEPKGS 286 Score = 31.2 bits (69), Expect = 2.6 Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 2/56 (3%) Query: 505 SPPPAPIYTPPPPAPHCPPPPPSAPTPP--IPSPPSTLPPPPQAPPPNRAPPPSRP 558 +PPP P+ P PPAP P + PP + S + + RA PP P Sbjct: 225 APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSP 280 Score = 30.4 bits (67), Expect = 4.5 Identities = 20/60 (33%), Positives = 24/60 (40%), Gaps = 8/60 (13%) Query: 506 PPPAPIYTPPPPAPHCPPPP-------PSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRP 558 PPP P+ T P P AP+ +P PPS P P+RAP P P Sbjct: 305 PPPTPVRTSSIPVQEAQEAPRKEEGATKKAPS-RLPLPPSFHIRPASQVYPDRAPEPDCP 363 >gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sapiens] Length = 2715 Score = 62.4 bits (150), Expect = 1e-09 Identities = 31/70 (44%), Positives = 34/70 (48%), Gaps = 14/70 (20%) Query: 504 SSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPP-------- 555 S PPP P + PP P CPPPPP PP+PSP PPPP +PPP Sbjct: 412 SPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSP----PPPPAQEEQEESPPPVVPATCSR 467 Query: 556 --SRPPPRPS 563 RPP PS Sbjct: 468 KRGRPPLTPS 477 Score = 58.5 bits (140), Expect = 2e-08 Identities = 28/50 (56%), Positives = 28/50 (56%), Gaps = 9/50 (18%) Query: 514 PPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPPRPS 563 PPP P P PPP P PPST PPPP PPP PPP PPP PS Sbjct: 403 PPPLTPPAPSPPPPLP------PPSTSPPPPLCPPP---PPPVSPPPLPS 443 Score = 58.2 bits (139), Expect = 2e-08 Identities = 27/54 (50%), Positives = 28/54 (51%), Gaps = 2/54 (3%) Query: 507 PPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPP 560 PPAP PP P P PPPP P PP P P LP PP PPP + PPP Sbjct: 408 PPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPP--PPPAQEEQEESPPP 459 Score = 51.6 bits (122), Expect = 2e-06 Identities = 33/82 (40%), Positives = 35/82 (42%), Gaps = 26/82 (31%) Query: 505 SPPPAPIYTPPPPAPHCPPP---PPSAPTPP---IPSPPST-----------------LP 541 SP P T PP P P P PP APTPP +P P LP Sbjct: 560 SPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELP 619 Query: 542 PPPQAPPPNRAPPPSRPPPRPS 563 PPP APPP PP PPP P+ Sbjct: 620 PPPPAPPP---PPAPSPPPAPA 638 Score = 49.3 bits (116), Expect = 9e-06 Identities = 29/72 (40%), Positives = 31/72 (43%), Gaps = 3/72 (4%) Query: 492 PAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPP--PQAPPP 549 PA P S+ PP P+ PPPP P PPP PS P PP PPP P Sbjct: 409 PAPSPPPPLPPPSTSPPPPLC-PPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSR 467 Query: 550 NRAPPPSRPPPR 561 R PP P R Sbjct: 468 KRGRPPLTPSQR 479 Score = 44.3 bits (103), Expect = 3e-04 Identities = 65/203 (32%), Positives = 85/203 (41%), Gaps = 33/203 (16%) Query: 375 WPTVDASYYGGRGVGGIKRMEVR-WGEKGSTEEGAKLEKAKNAR--VKMPEQEYEFP--E 429 W TVDA R + +E R WG + EE A LE A+ + V P E P E Sbjct: 1765 WSTVDARR---RCWYRCRILEYRPWGPR---EEPAHLEAAEENQTIVHSPAPSSEPPGGE 1818 Query: 430 PRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQPGDTGRCINFTRVK- 488 L+ ++ P +P + +SPI+ L LR D S P P R + R+K Sbjct: 1819 DPPLDTDVLVPGAPER-HSPIQN----LDPPLRP--DSGSAPPPAP----RSFSGARIKV 1867 Query: 489 -NNQPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPP-PPSAPTPPI----PSPPSTLPP 542 N P++ PL P P +P H P P P PP PSP + PP Sbjct: 1868 PNYSPSRRPLGGVSFGPLPSPG---SPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPP 1924 Query: 543 PPQ-APPPNRAPPPSRPPPRPSV 564 P + A PP + P R PP SV Sbjct: 1925 PSRWASPPLKTSPQLRVPPPTSV 1947 Score = 43.1 bits (100), Expect = 7e-04 Identities = 28/71 (39%), Positives = 32/71 (45%), Gaps = 19/71 (26%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAPTPPI--------PSPP------STLPPPPQAPP--P 549 PPPAP PPPPAP PP P ++ P+ PS S L PPP P P Sbjct: 621 PPPAP---PPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAP 677 Query: 550 NRAPPPSRPPP 560 PPP+ P Sbjct: 678 EPEPPPADDSP 688 Score = 42.7 bits (99), Expect = 9e-04 Identities = 21/51 (41%), Positives = 26/51 (50%), Gaps = 7/51 (13%) Query: 514 PPPPAPHCPPP--PPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPPRP 562 P PP P PP +PP+P P+ +P PP+AP PPS P P P Sbjct: 552 PKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAP-----TPPSTPVPLP 597 Score = 42.4 bits (98), Expect = 0.001 Identities = 24/77 (31%), Positives = 28/77 (36%), Gaps = 21/77 (27%) Query: 504 SSPPPAPIYTPPPPAPHCPPPPPSAPTP---------------------PIPSPPSTLPP 542 ++ PP P P P+P P PPS P P +P PP PP Sbjct: 568 TTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPP 627 Query: 543 PPQAPPPNRAPPPSRPP 559 PP PP SR P Sbjct: 628 PPAPSPPPAPATSSRRP 644 Score = 41.6 bits (96), Expect = 0.002 Identities = 26/77 (33%), Positives = 31/77 (40%), Gaps = 22/77 (28%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAPTPPI--------PS-------------PPSTLPPPP 544 PPP P PPPPAP PP P ++ P+ PS PP P P Sbjct: 619 PPPPPA-PPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAP 677 Query: 545 QAPPPNRAPPPSRPPPR 561 + PP P+ P PR Sbjct: 678 EPEPPPADDSPAEPEPR 694 Score = 40.0 bits (92), Expect = 0.006 Identities = 25/68 (36%), Positives = 29/68 (42%), Gaps = 21/68 (30%) Query: 514 PPPPAPHCPPPPPSAPTPPIPSPPSTLP--------PPPQA----------PPPNRAPPP 555 PPPPAP PPPP+ PP P+ S P P +A PPP AP Sbjct: 620 PPPPAP---PPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEA 676 Query: 556 SRPPPRPS 563 P P P+ Sbjct: 677 PEPEPPPA 684 Score = 39.7 bits (91), Expect = 0.007 Identities = 19/36 (52%), Positives = 22/36 (61%), Gaps = 4/36 (11%) Query: 533 IPSPPSTLP---PPPQAPPPNRAPPPSR-PPPRPSV 564 +P PP T P PPP PPP+ +PPP PPP P V Sbjct: 401 LPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPV 436 Score = 36.2 bits (82), Expect = 0.082 Identities = 15/35 (42%), Positives = 18/35 (51%) Query: 526 PSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPP 560 P+A PP L PP +PPP PP + PPP Sbjct: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPP 426 Score = 33.9 bits (76), Expect = 0.41 Identities = 21/61 (34%), Positives = 25/61 (40%), Gaps = 4/61 (6%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRP--PPRPS 563 PP P +P P PP P P+ PPPP PPP S P PPR + Sbjct: 2218 PPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPP--PPPLTLVLSSGPASPPRQA 2275 Query: 564 V 564 + Sbjct: 2276 I 2276 Score = 32.3 bits (72), Expect = 1.2 Identities = 27/85 (31%), Positives = 34/85 (40%), Gaps = 18/85 (21%) Query: 491 QPAKYPLNNAYHTSSPPPAPIYTPPPPA---PHCPPPPPSAP------TPPIPS-----P 536 +P + H S P AP+ T P A PH P + P P+ + Sbjct: 690 EPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLL 749 Query: 537 PSTLPPP-PQAPPPNRAPPPSRPPP 560 P LPPP PQ PP P P + PP Sbjct: 750 PQALPPPQPQLQPP---PSPQQMPP 771 Score = 32.0 bits (71), Expect = 1.5 Identities = 19/65 (29%), Positives = 24/65 (36%), Gaps = 7/65 (10%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAP-------PPSRP 558 PP +P P PP P +P P +P+ S P P RA P Sbjct: 434 PPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTS 493 Query: 559 PPRPS 563 PP P+ Sbjct: 494 PPTPT 498 Score = 32.0 bits (71), Expect = 1.5 Identities = 20/54 (37%), Positives = 21/54 (38%), Gaps = 4/54 (7%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPP 559 P P P+ PP P P P S PP P L P APPP PP Sbjct: 2210 PVPPPVKQPPLPPTISPTAPTSWTLPPGP----LLGVLPVVGVVRPAPPPPPPP 2259 Score = 31.2 bits (69), Expect = 2.6 Identities = 18/50 (36%), Positives = 21/50 (42%), Gaps = 3/50 (6%) Query: 493 AKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPP 542 A PL + PPP + T P PP AP+PP PP L P Sbjct: 1929 ASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPP---PPEDLGP 1975 >gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] Length = 502 Score = 61.6 bits (148), Expect = 2e-09 Identities = 34/82 (41%), Positives = 39/82 (47%), Gaps = 8/82 (9%) Query: 490 NQPAKYPL--NNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPST------LP 541 NQ + P+ N + PP P+ PPP PPPP PP P PP+T P Sbjct: 324 NQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPATGRSGPLPP 383 Query: 542 PPPQAPPPNRAPPPSRPPPRPS 563 PPP A P PPP PPP PS Sbjct: 384 PPPGAGGPPMPPPPPPPPPPPS 405 Score = 58.9 bits (141), Expect = 1e-08 Identities = 30/70 (42%), Positives = 35/70 (50%), Gaps = 10/70 (14%) Query: 505 SPPPAPIYTPPPPAPHCPPPPP------SAPTPPIP----SPPSTLPPPPQAPPPNRAPP 554 +PPP PPPP PPPPP S P PP P PP PPPP PPP+ Sbjct: 350 APPPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNG 409 Query: 555 PSRPPPRPSV 564 P+ PP P++ Sbjct: 410 PAPPPLPPAL 419 Score = 55.1 bits (131), Expect = 2e-07 Identities = 29/64 (45%), Positives = 32/64 (50%), Gaps = 7/64 (10%) Query: 506 PPPAPIYTPPPPAPHC------PPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPP 559 PPP PPPP P PPPPP A PP+P PP PPPP + APPP P Sbjct: 360 PPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPP-PPPPPSSGNGPAPPPLPPA 418 Query: 560 PRPS 563 P+ Sbjct: 419 LVPA 422 Score = 43.5 bits (101), Expect = 5e-04 Identities = 28/62 (45%), Positives = 28/62 (45%), Gaps = 20/62 (32%) Query: 519 PHCPPPPPS-----APTPPI---------PSPPSTL---PPPPQ---APPPNRAPPPSRP 558 P PPPPPS P PPI P PP L PPPP PPP R PP P Sbjct: 312 PLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPP 371 Query: 559 PP 560 PP Sbjct: 372 PP 373 Score = 42.0 bits (97), Expect = 0.001 Identities = 24/60 (40%), Positives = 24/60 (40%), Gaps = 6/60 (10%) Query: 506 PPPAPIYT------PPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPP 559 PPP P T PPPP PP P P PP P P S P P PP P P Sbjct: 368 PPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAP 427 Score = 41.6 bits (96), Expect = 0.002 Identities = 27/63 (42%), Positives = 29/63 (46%), Gaps = 13/63 (20%) Query: 506 PPPA-----PIYTPPPPA--PHCPPPPPSAPTPPI----PSPPSTLPPPPQAPPPNRAPP 554 PPPA P+ PPP A P PPPPP P PP P+PP PP P AP Sbjct: 371 PPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPL--PPALVPAGGLAPG 428 Query: 555 PSR 557 R Sbjct: 429 GGR 431 >gi|52485606 formin-like 2 [Homo sapiens] Length = 1092 Score = 61.6 bits (148), Expect = 2e-09 Identities = 27/52 (51%), Positives = 32/52 (61%), Gaps = 1/52 (1%) Query: 504 SSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPS-TLPPPPQAPPPNRAPP 554 + P P+ PPPP P PPPPP P PP+P P + T+P PP APP APP Sbjct: 545 NGPVTPPMPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLAPPLPSAPP 596 Score = 53.1 bits (126), Expect = 6e-07 Identities = 26/50 (52%), Positives = 29/50 (58%), Gaps = 5/50 (10%) Query: 514 PPPPAPHCPPPPPSAPTPP-IPSPPSTLPPPPQAPPPNRAPPPSRPPPRP 562 PPPP PP PPS+ TP + + P T P PP PPP PPP PPP P Sbjct: 527 PPPP----PPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPP 572 Score = 52.8 bits (125), Expect = 8e-07 Identities = 26/60 (43%), Positives = 27/60 (45%), Gaps = 2/60 (3%) Query: 504 SSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPPRPS 563 SS P + P P PPPPP P PP P PP PPP P P P PP PS Sbjct: 536 SSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPP--PPPLPGPAAETVPAPPLAPPLPS 593 Score = 52.0 bits (123), Expect = 1e-06 Identities = 27/56 (48%), Positives = 30/56 (53%), Gaps = 6/56 (10%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAP-TPPIPSPPSTLPPPPQAPPPNRAPPPSRPPP 560 PPP P P PP+ P + P TPP+P PP PPPP PPP PPP P P Sbjct: 527 PPPPP---PLPPSSDTPETVQNGPVTPPMPPPP--PPPPPPPPPPPPPPPPPLPGP 577 Score = 50.1 bits (118), Expect = 5e-06 Identities = 24/50 (48%), Positives = 27/50 (54%), Gaps = 2/50 (4%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPP-PNRAPP 554 PPP P PPPP P PPP P +P+PP PP P APP P + P Sbjct: 555 PPPPPPPPPPPPPPPPPPPLPGPAAETVPAPP-LAPPLPSAPPLPGTSSP 603 Score = 49.7 bits (117), Expect = 7e-06 Identities = 23/51 (45%), Positives = 24/51 (47%), Gaps = 10/51 (19%) Query: 522 PPPPPSAPTPPIPSPPSTL----------PPPPQAPPPNRAPPPSRPPPRP 562 P PPP P PP P T+ PPPP PPP PPP PPP P Sbjct: 525 PLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLP 575 Score = 42.4 bits (98), Expect = 0.001 Identities = 21/54 (38%), Positives = 24/54 (44%), Gaps = 14/54 (25%) Query: 523 PPPPSAPTPPIPSPPSTLPP--------------PPQAPPPNRAPPPSRPPPRP 562 P +A + P+P PP LPP PP PPP PPP PPP P Sbjct: 516 PTMGAASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPP 569 >gi|122937496 WAS/WASL interacting protein family, member 3 [Homo sapiens] Length = 483 Score = 61.6 bits (148), Expect = 2e-09 Identities = 33/77 (42%), Positives = 37/77 (48%), Gaps = 20/77 (25%) Query: 504 SSPPPAPIYTPPPPAPHCPPPPPSAPTP---------PIPSPPSTL---------PPPPQ 545 ++PP + PPPP P PPPPP P P P+ SPP L PP P Sbjct: 164 TAPPRPNVPAPPPPTP--PPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPC 221 Query: 546 APPPNRAPPPSRPPPRP 562 APPP PPP PPP P Sbjct: 222 APPPPPPPPPPTPPPLP 238 Score = 53.5 bits (127), Expect = 5e-07 Identities = 32/89 (35%), Positives = 37/89 (41%), Gaps = 16/89 (17%) Query: 486 RVKNNQPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSA----------PTP---- 531 R+ N A A + P P TPPPP P PPP PS+ P P Sbjct: 151 RLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKG 210 Query: 532 --PIPSPPSTLPPPPQAPPPNRAPPPSRP 558 P+ +PP PPP PPP PPP P Sbjct: 211 NLPVVAPPVPCAPPPPPPPPPPTPPPLPP 239 Score = 48.1 bits (113), Expect = 2e-05 Identities = 31/107 (28%), Positives = 42/107 (39%), Gaps = 34/107 (31%) Query: 489 NNQPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPST--------- 539 ++ P K PL + + P+ PP P PPPPP PTPP P PP++ Sbjct: 192 SSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPP-PLPPASVLSDKAVKP 250 Query: 540 ---------LPPP---------------PQAPPPNRAPPPSRPPPRP 562 +PPP P +P + PP+ PPP P Sbjct: 251 QLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLP 297 Score = 43.9 bits (102), Expect = 4e-04 Identities = 47/155 (30%), Positives = 54/155 (34%), Gaps = 40/155 (25%) Query: 428 PEPRNLNNNMRRPSSPRKWYSPIKGKLDALWVLLRKGYDRVSVMRPQPGDTGRCINFTRV 487 P PR N + P P SP G R R +V P P Sbjct: 131 PSPRLPNKTISGPLIPPA--SPRLGNTSEAHGAARTAPPRPNVPAPPP------------ 176 Query: 488 KNNQPAKYPLNNAYHTSSPPPAPIYTPP------------PPAPHCPPPPPSAPTPPIPS 535 P PL +SSP P+ +PP PP P PPPPP P P Sbjct: 177 PTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPP-----P-PP 230 Query: 536 PPSTLPPPP------QAPPPNRAP--PPSRPPPRP 562 PP+ P PP +A P AP P PPP P Sbjct: 231 PPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLP 265 Score = 42.7 bits (99), Expect = 9e-04 Identities = 18/32 (56%), Positives = 20/32 (62%), Gaps = 3/32 (9%) Query: 517 PAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPP 548 P P PPPP P PP+ +PP PPPP APP Sbjct: 2 PVPPPPPPPLPPPPPPLGAPP---PPPPSAPP 30 Score = 42.7 bits (99), Expect = 9e-04 Identities = 22/38 (57%), Positives = 23/38 (60%), Gaps = 11/38 (28%) Query: 522 PPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPP 559 PPPPP PP+P P PPP APPP PPPS PP Sbjct: 4 PPPPP----PPLPPP----PPPLGAPPP---PPPSAPP 30 Score = 41.6 bits (96), Expect = 0.002 Identities = 17/35 (48%), Positives = 20/35 (57%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTL 540 PPP P PPPP P PPPP PP+ + S+L Sbjct: 4 PPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSL 38 Score = 41.2 bits (95), Expect = 0.003 Identities = 22/46 (47%), Positives = 22/46 (47%), Gaps = 5/46 (10%) Query: 514 PPPPAPHCPPPPP--SAPTPPIPSPPSTLPPPPQAPPPNRAPPPSR 557 PPPP P PPPPP AP PP PPS P RA P R Sbjct: 4 PPPPPPPLPPPPPPLGAPPPP---PPSAPPVSTDTSSLRRADPKGR 46 Score = 41.2 bits (95), Expect = 0.003 Identities = 33/106 (31%), Positives = 44/106 (41%), Gaps = 16/106 (15%) Query: 473 PQPGDTGRCINFTRVKNNQPAKYPLNNAYHTSSPPPAPIYTP--------PPPAPHCPPP 524 P P T + V +++ K L + PPP P+ P P +P Sbjct: 228 PPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQ 287 Query: 525 PPSAPTPPIP-----SPPSTLPPPPQAPPPNRA--PPPSRPPPRPS 563 P AP PP+P SP ++LP PP P N + PP PP PS Sbjct: 288 EPPAPPPPLPPYASCSPRASLPAPP-LPGVNSSSETPPPLPPKSPS 332 Score = 40.0 bits (92), Expect = 0.006 Identities = 32/85 (37%), Positives = 37/85 (43%), Gaps = 16/85 (18%) Query: 492 PAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPP-----PPPSAPTPPIP---SPPSTLPP- 542 P YP A S P PP P P PP P S P PP+P S T PP Sbjct: 269 PCGYPGLKAEPAS--PAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPL 326 Query: 543 PPQAP----PPNRAPPPSRP-PPRP 562 PP++P PP +A + P PP P Sbjct: 327 PPKSPSFQAPPQKAGAQALPAPPAP 351 Score = 38.1 bits (87), Expect = 0.022 Identities = 20/60 (33%), Positives = 22/60 (36%), Gaps = 6/60 (10%) Query: 506 PPPAPIYTPPPPAPHCPPPP------PSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPP 559 PPP P Y P P PP S PP+P + PPQ P P PP Sbjct: 293 PPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPP 352 Score = 37.7 bits (86), Expect = 0.028 Identities = 21/36 (58%), Positives = 21/36 (58%), Gaps = 6/36 (16%) Query: 529 PTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPPRPSV 564 P PP P PP LPPPP PP APPP PP P V Sbjct: 2 PVPPPPPPP--LPPPP---PPLGAPPPP-PPSAPPV 31 Score = 35.4 bits (80), Expect = 0.14 Identities = 19/46 (41%), Positives = 21/46 (45%), Gaps = 14/46 (30%) Query: 518 APHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPPRPS 563 A PP P+ P PP P+P PP PPP PPP PS Sbjct: 161 AARTAPPRPNVPAPPPPTP------PP--------PPPPLPPPLPS 192 Score = 31.6 bits (70), Expect = 2.0 Identities = 14/27 (51%), Positives = 16/27 (59%), Gaps = 3/27 (11%) Query: 540 LPPPPQAPPPNRAPPP---SRPPPRPS 563 +P PP PPP PPP + PPP PS Sbjct: 1 MPVPPPPPPPLPPPPPPLGAPPPPPPS 27 Score = 29.6 bits (65), Expect = 7.7 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 11/69 (15%) Query: 503 TSSPPPAPIYTPPPPAPHCPPPPPSAPT-PPIPSPPSTLP-------PPPQAPPPNRAPP 554 + +PPP P P P+ PP A P P+PP + P P A PP Sbjct: 320 SETPPPLP---PKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPP 376 Query: 555 PSRPPPRPS 563 P+ P P+ Sbjct: 377 PAPPARSPT 385 >gi|169163027 PREDICTED: similar to Putative acrosin-like protease [Homo sapiens] Length = 355 Score = 60.5 bits (145), Expect = 4e-09 Identities = 32/75 (42%), Positives = 34/75 (45%), Gaps = 15/75 (20%) Query: 504 SSPPPAPIYTPPPPAP-------------HCPPPPPSAPTPPI--PSPPSTLPPPPQAPP 548 S+ PP P PPP P PPP P P PP P PP + PPPP PP Sbjct: 233 SATPPPPTTRPPPIRPPFSHPLSAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPPPP 292 Query: 549 PNRAPPPSRPPPRPS 563 PPP PPP PS Sbjct: 293 SPLPPPPPPPPPTPS 307 Score = 58.9 bits (141), Expect = 1e-08 Identities = 26/53 (49%), Positives = 29/53 (54%), Gaps = 3/53 (5%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRP 558 PPP P+ PP P P PP +P PP P PPS LPPPP PPP + P Sbjct: 264 PPPRPL---PPRPPAAQPRPPPSPPPPPPPPPSPLPPPPPPPPPTPSSTTKLP 313 Score = 48.9 bits (115), Expect = 1e-05 Identities = 23/51 (45%), Positives = 25/51 (49%) Query: 491 QPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLP 541 QP PL + P P P PPPP P P PPP P PP PS + LP Sbjct: 263 QPPPRPLPPRPPAAQPRPPPSPPPPPPPPPSPLPPPPPPPPPTPSSTTKLP 313 >gi|239753435 PREDICTED: hypothetical protein XP_002345651 [Homo sapiens] Length = 218 Score = 60.1 bits (144), Expect = 5e-09 Identities = 29/55 (52%), Positives = 33/55 (60%), Gaps = 5/55 (9%) Query: 508 PAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPPRP 562 P +++PPPP P P PP P PP P PP+ PP P PPP R P P PPPRP Sbjct: 18 PCGLWSPPPPLP--PRKPPRPPKPPRPLPPN--PPRPPLPPP-RPPKPPLPPPRP 67 Score = 52.4 bits (124), Expect = 1e-06 Identities = 25/53 (47%), Positives = 27/53 (50%), Gaps = 3/53 (5%) Query: 504 SSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPS 556 S PPP P PP P P PP+ P PP+P P PP P PPP PPS Sbjct: 23 SPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPP---RPPKPPLPPPRPPKPPS 72 Score = 37.0 bits (84), Expect = 0.048 Identities = 17/35 (48%), Positives = 17/35 (48%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTL 540 P P P P PP P PP P P P P PPS L Sbjct: 40 PRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPL 74 Score = 36.2 bits (82), Expect = 0.082 Identities = 17/48 (35%), Positives = 22/48 (45%) Query: 505 SPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRA 552 +PP P+ P PP P PPP P P P+ S + P P + A Sbjct: 46 NPPRPPLPPPRPPKPPLPPPRPPKPPSPLGLAQSKVTLFPSISPSSMA 93 Score = 30.8 bits (68), Expect = 3.4 Identities = 17/44 (38%), Positives = 20/44 (45%), Gaps = 2/44 (4%) Query: 488 KNNQPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTP 531 K +P K P + PP P P PP P PP PP P+P Sbjct: 32 KPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLP--PPRPPKPPSP 73 >gi|239747993 PREDICTED: hypothetical protein XP_002346504 [Homo sapiens] Length = 218 Score = 60.1 bits (144), Expect = 5e-09 Identities = 29/55 (52%), Positives = 33/55 (60%), Gaps = 5/55 (9%) Query: 508 PAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPPRP 562 P +++PPPP P P PP P PP P PP+ PP P PPP R P P PPPRP Sbjct: 18 PCGLWSPPPPLP--PRKPPRPPKPPRPLPPN--PPRPPLPPP-RPPKPPLPPPRP 67 Score = 52.4 bits (124), Expect = 1e-06 Identities = 25/53 (47%), Positives = 27/53 (50%), Gaps = 3/53 (5%) Query: 504 SSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPS 556 S PPP P PP P P PP+ P PP+P P PP P PPP PPS Sbjct: 23 SPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPP---RPPKPPLPPPRPPKPPS 72 Score = 37.0 bits (84), Expect = 0.048 Identities = 17/35 (48%), Positives = 17/35 (48%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTL 540 P P P P PP P PP P P P P PPS L Sbjct: 40 PRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPL 74 Score = 36.2 bits (82), Expect = 0.082 Identities = 17/48 (35%), Positives = 22/48 (45%) Query: 505 SPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRA 552 +PP P+ P PP P PPP P P P+ S + P P + A Sbjct: 46 NPPRPPLPPPRPPKPPLPPPRPPKPPSPLGLAQSKVTLFPSISPSSMA 93 Score = 30.8 bits (68), Expect = 3.4 Identities = 17/44 (38%), Positives = 20/44 (45%), Gaps = 2/44 (4%) Query: 488 KNNQPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTP 531 K +P K P + PP P P PP P PP PP P+P Sbjct: 32 KPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLP--PPRPPKPPSP 73 >gi|239741891 PREDICTED: hypothetical protein XP_002342316 [Homo sapiens] Length = 218 Score = 60.1 bits (144), Expect = 5e-09 Identities = 29/55 (52%), Positives = 33/55 (60%), Gaps = 5/55 (9%) Query: 508 PAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPPRP 562 P +++PPPP P P PP P PP P PP+ PP P PPP R P P PPPRP Sbjct: 18 PCGLWSPPPPLP--PRKPPRPPKPPRPLPPN--PPRPPLPPP-RPPKPPLPPPRP 67 Score = 52.4 bits (124), Expect = 1e-06 Identities = 25/53 (47%), Positives = 27/53 (50%), Gaps = 3/53 (5%) Query: 504 SSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPS 556 S PPP P PP P P PP+ P PP+P P PP P PPP PPS Sbjct: 23 SPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPP---RPPKPPLPPPRPPKPPS 72 Score = 37.0 bits (84), Expect = 0.048 Identities = 17/35 (48%), Positives = 17/35 (48%) Query: 506 PPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTL 540 P P P P PP P PP P P P P PPS L Sbjct: 40 PRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPL 74 Score = 36.2 bits (82), Expect = 0.082 Identities = 17/48 (35%), Positives = 22/48 (45%) Query: 505 SPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRA 552 +PP P+ P PP P PPP P P P+ S + P P + A Sbjct: 46 NPPRPPLPPPRPPKPPLPPPRPPKPPSPLGLAQSKVTLFPSISPSSMA 93 Score = 30.8 bits (68), Expect = 3.4 Identities = 17/44 (38%), Positives = 20/44 (45%), Gaps = 2/44 (4%) Query: 488 KNNQPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTP 531 K +P K P + PP P P PP P PP PP P+P Sbjct: 32 KPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLP--PPRPPKPPSP 73 >gi|7706501 WW domain binding protein 11 [Homo sapiens] Length = 641 Score = 59.7 bits (143), Expect = 7e-09 Identities = 32/72 (44%), Positives = 35/72 (48%), Gaps = 13/72 (18%) Query: 506 PPPAPIYTPPPPAPHC---------PPPPPSAPTPPIPSPPSTLP--PPPQAPPPNRAP- 553 PP AP + PP P P PPP P P P PP LP PPP+ PPP P Sbjct: 435 PPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPP 494 Query: 554 -PPSRPPPRPSV 564 PP PPPRP + Sbjct: 495 APPGIPPPRPGM 506 Score = 55.1 bits (131), Expect = 2e-07 Identities = 38/102 (37%), Positives = 40/102 (39%), Gaps = 12/102 (11%) Query: 475 PGDTGRCINFTRVKNNQPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPP-PPPSAPTP-- 531 PG F R + PL PP P PP P P PP PPP P P Sbjct: 432 PGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRL 491 Query: 532 PIPSPPSTLPP------PPQAPPPNRAPP---PSRPPPRPSV 564 P P+PP PP PP PP APP P P P P V Sbjct: 492 PPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGV 533 Score = 53.1 bits (126), Expect = 6e-07 Identities = 32/73 (43%), Positives = 35/73 (47%), Gaps = 16/73 (21%) Query: 505 SPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLP--PPPQAPPPNRAP--------- 553 S PP+ I PP P P PPP+ P P P PP+ LP PPP APP R P Sbjct: 396 SVPPSQIQAPPMPGPPPLGPPPAPPLRP-PGPPTGLPPGPPPGAPPFLRPPGMPGLRGPL 454 Query: 554 ----PPSRPPPRP 562 PP PP RP Sbjct: 455 PRLLPPGPPPGRP 467 Score = 44.7 bits (104), Expect = 2e-04 Identities = 23/58 (39%), Positives = 27/58 (46%), Gaps = 7/58 (12%) Query: 506 PPPA--PIYTPPPPAPHCPPPPPSAPTPPI-----PSPPSTLPPPPQAPPPNRAPPPS 556 PPP P PPP P PPP P PP+ P+PP PP P P + PP+ Sbjct: 482 PPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPN 539 Score = 38.9 bits (89), Expect = 0.013 Identities = 21/48 (43%), Positives = 22/48 (45%), Gaps = 3/48 (6%) Query: 518 APHCPPPPPSAPTPPIPSPPSTLPPP--PQAPP-PNRAPPPSRPPPRP 562 AP PP PP+P PP PPP P PP P PP PP P Sbjct: 392 APPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAP 439 Score = 36.6 bits (83), Expect = 0.063 Identities = 19/40 (47%), Positives = 21/40 (52%), Gaps = 4/40 (10%) Query: 524 PPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPPRPS 563 PP S P I +PP PPP PPP PP RPP P+ Sbjct: 393 PPQSVPPSQIQAPPMP-GPPPLGPPP---APPLRPPGPPT 428 Score = 33.9 bits (76), Expect = 0.41 Identities = 23/55 (41%), Positives = 25/55 (45%), Gaps = 7/55 (12%) Query: 506 PPPAPIYTPPPPA----PHCPPPPPSAPTPPIPSPPSTLP-PPPQAPPPNRAPPP 555 PPPAP PPP P PP P PP PP+ LP P + PPN P Sbjct: 492 PPPAPPGIPPPRPGMMRPPLVPP--LGPAPPGLFPPAPLPNPGVLSAPPNLIQRP 544 Score = 31.6 bits (70), Expect = 2.0 Identities = 22/72 (30%), Positives = 24/72 (33%), Gaps = 21/72 (29%) Query: 514 PPPPAPHCPP-------PPPSAPTPPIPSPPSTLPPP--------------PQAPPPNRA 552 P P PH P P P A P I S PP P+ PP + Sbjct: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKP 199 Query: 553 PPPSRPPPRPSV 564 P P PP P V Sbjct: 200 PGPPPGPPPPQV 211 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 59.3 bits (142), Expect = 9e-09 Identities = 34/78 (43%), Positives = 40/78 (51%), Gaps = 18/78 (23%) Query: 504 SSPPPAPIYTP------PPPAPHCPPP---PPSAPTPPI---PSPPSTLP------PPPQ 545 S PP P+ P PP +P PP PPS PP+ PSPP++ P PPPQ Sbjct: 666 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725 Query: 546 APPPNRAPPPSRPPPRPS 563 APPP APP PP P+ Sbjct: 726 APPPLAAPPLQVPPSPPA 743 Score = 58.2 bits (139), Expect = 2e-08 Identities = 36/92 (39%), Positives = 45/92 (48%), Gaps = 19/92 (20%) Query: 491 QPAKYPLNNAYHTSSP---------PPAPIYTPPPPAPH---CPPP--PPSAPTPP---I 533 Q A PL + + P PP+P+ TPPP P PPP PP+ +PP + Sbjct: 547 QTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGL 606 Query: 534 PSPPST--LPPPPQAPPPNRAPPPSRPPPRPS 563 PSPP + PPPQAPP PP PP P+ Sbjct: 607 PSPPLSPLATPPPQAPPXLALPPLQAPPSPPA 638 Score = 55.1 bits (131), Expect = 2e-07 Identities = 30/74 (40%), Positives = 41/74 (55%), Gaps = 7/74 (9%) Query: 492 PAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPP---PPPSAPTPPIPSPPSTLPP-PPQAP 547 P+ P + A + + PP + PP +P P PPP AP PP+ +PP +PP PP +P Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP-PPLAAPPLQVPPSPPASP 745 Query: 548 P--PNRAPPPSRPP 559 P P+ PPP PP Sbjct: 746 PMSPSATPPPRVPP 759 Score = 55.1 bits (131), Expect = 2e-07 Identities = 31/65 (47%), Positives = 36/65 (55%), Gaps = 7/65 (10%) Query: 504 SSPPPAPIYTPPP--PAPHCPPP---PPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRP 558 +SPP +P TPPP P P PP PPS P P SP +T PPP+ PP APP P Sbjct: 712 ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSAT--PPPRVPPLLAAPPLQVP 769 Query: 559 PPRPS 563 P P+ Sbjct: 770 PSPPA 774 Score = 54.3 bits (129), Expect = 3e-07 Identities = 31/70 (44%), Positives = 36/70 (51%), Gaps = 10/70 (14%) Query: 504 SSPPPAPIYTPP---PPAPHCPP------PPPSAPTPPIPSPPSTLPPPPQAPPPNRAP- 553 +SPP +P TPP PP+ PP PP S P P +PP PPP APP P Sbjct: 681 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPS 740 Query: 554 PPSRPPPRPS 563 PP+ PP PS Sbjct: 741 PPASPPMSPS 750 Score = 54.3 bits (129), Expect = 3e-07 Identities = 32/92 (34%), Positives = 43/92 (46%), Gaps = 17/92 (18%) Query: 486 RVKNNQPAKYPLNNAYHTSSPPPAPIYTPP---PPAPHCPPP-----------PPSAPTP 531 +V + PA P++ + P P+ PP PP+P PP PP P Sbjct: 705 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAP 764 Query: 532 PI---PSPPSTLPPPPQAPPPNRAPPPSRPPP 560 P+ PSPP++LP P A PP +APP PP Sbjct: 765 PLQVPPSPPASLPMSPLAKPPPQAPPALATPP 796 Score = 52.0 bits (123), Expect = 1e-06 Identities = 32/77 (41%), Positives = 37/77 (48%), Gaps = 10/77 (12%) Query: 496 PLNNAYHTSSPP----PAPIYTPPPPAPHCPPP-----PPSAPTPPIPSPPSTL-PPPPQ 545 PL N + PP AP+ TP P CP P PPS T P P PS++ PPPQ Sbjct: 534 PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQ 593 Query: 546 APPPNRAPPPSRPPPRP 562 APP +PP P P Sbjct: 594 APPALASPPLQGLPSPP 610 Score = 51.6 bits (122), Expect = 2e-06 Identities = 49/178 (27%), Positives = 74/178 (41%), Gaps = 7/178 (3%) Query: 389 GGIKRMEVRWGEKGSTEEGAKLEKAKNAR--VKMPEQEYEFPEPRNLNNNMRRP--SSPR 444 GG++R R +T + +AR + P + P+P+ L +R P + PR Sbjct: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ-PKPKGLQA-LRPPQVTPPR 289 Query: 445 KWYSPIKGKLDALWVLLRKGYDRVSVMRPQPGDTGRCINFTRVKNNQPAKYPLNNAYHTS 504 K +P G L + + + P P + + T + + P PL A + Sbjct: 290 KDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPAT-LPPSPPLATPLPLAPPSP 348 Query: 505 SPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPPRP 562 S PP+ P PPA PPS TPP+ +PPS PP P + P + PP P Sbjct: 349 SAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSP 406 Score = 50.1 bits (118), Expect = 5e-06 Identities = 28/63 (44%), Positives = 32/63 (50%), Gaps = 3/63 (4%) Query: 504 SSPPPAPIYTPPPPAPH--CPPPPPSAPTPPIPSPPSTL-PPPPQAPPPNRAPPPSRPPP 560 +SPP +P TPPP P PP P+PP P S L PPPQAPP PP P Sbjct: 743 ASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPS 802 Query: 561 RPS 563 P+ Sbjct: 803 PPA 805 Score = 50.1 bits (118), Expect = 5e-06 Identities = 32/85 (37%), Positives = 41/85 (48%), Gaps = 17/85 (20%) Query: 492 PAKYPLNNAYHTS-SPPPAPIYTPPPPAP--------HCPPPPPSAPT------PPIPSP 536 PA +P + S S P +P+ TPPP AP PP PP++PT PP P P Sbjct: 804 PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 863 Query: 537 PSTLPPP--PQAPPPNRAPPPSRPP 559 +++ P A P PPPSR P Sbjct: 864 DTSVSGPRLTLALAPGPPPPPSRSP 888 Score = 49.3 bits (116), Expect = 9e-06 Identities = 31/81 (38%), Positives = 38/81 (46%), Gaps = 22/81 (27%) Query: 505 SPPPAPIYTPPPPAP--------HCPPPPPSAP-----TPPIPSPPSTL-------PPPP 544 SPP +P+ TPPP AP PP PP++P P P P+ L P P Sbjct: 608 SPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP 667 Query: 545 QAPPPNRAP--PPSRPPPRPS 563 PP +AP PP+ PP PS Sbjct: 668 PPSPPVQAPFSPPASPPVSPS 688 Score = 47.8 bits (112), Expect = 3e-05 Identities = 30/88 (34%), Positives = 39/88 (44%), Gaps = 11/88 (12%) Query: 486 RVKNNQPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQ 545 +V + PA P++ PP AP PP P PP S P SP ++LP P Sbjct: 767 QVPPSPPASLPMSPL--AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 824 Query: 546 APPPNRAPP---------PSRPPPRPSV 564 A PP +APP P PP P++ Sbjct: 825 ATPPPQAPPVLAAPLLQVPPSPPASPTL 852 Score = 42.7 bits (99), Expect = 9e-04 Identities = 32/94 (34%), Positives = 40/94 (42%), Gaps = 21/94 (22%) Query: 492 PAKYPLNNAYHTSSPPPAPIYTP------PPPAPHCPPPPPSAP---TPPI---PSPPST 539 P + P + A PPA P PP +P PPP + P PP+ PSPP++ Sbjct: 580 PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS 639 Query: 540 LPPPPQAPPPNRAP---------PPSRPPPRPSV 564 P P A P +AP P PPP P V Sbjct: 640 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV 673 Score = 42.0 bits (97), Expect = 0.001 Identities = 25/59 (42%), Positives = 28/59 (47%), Gaps = 7/59 (11%) Query: 507 PPAPIYTPP-PPAPHCPPPPPSA-----PTPPIPSPPSTLPPPPQAPP-PNRAPPPSRP 558 PPA + TPP P PPP TP + +PP P P QAPP P PPP P Sbjct: 526 PPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETP 584 Score = 40.8 bits (94), Expect = 0.003 Identities = 25/78 (32%), Positives = 37/78 (47%), Gaps = 3/78 (3%) Query: 488 KNNQPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSA--PTPPIPSPPSTLPPPPQ 545 K+ PA PL+++ + P P PP + P P+ P+PP+ +P PP P Sbjct: 290 KDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSP- 348 Query: 546 APPPNRAPPPSRPPPRPS 563 + PP+ PS P PS Sbjct: 349 SAPPSLQTLPSPPATPPS 366 Score = 40.8 bits (94), Expect = 0.003 Identities = 28/80 (35%), Positives = 34/80 (42%), Gaps = 17/80 (21%) Query: 500 AYHTSSPPPAPIYTPPPPA------PHCPPPPPSAPTPPIPSPPSTLPPPPQ---AP--- 547 A H+ P + + PP P PP S TPP+ + PS PPP Q AP Sbjct: 496 ASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTT 555 Query: 548 -----PPNRAPPPSRPPPRP 562 PP AP P + PP P Sbjct: 556 PHLETPPCPAPCPLQAPPSP 575 Score = 33.5 bits (75), Expect = 0.53 Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 5/60 (8%) Query: 504 SSPPPAPIYTPPPPAPHCPPPPPSAPTPPI-PSPPSTLPPPPQAPPPNRAPPPSRPPPRP 562 S P AP ++P P P P PP+ +P +PP P A P +AP R PP P Sbjct: 806 SFPGQAP-FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP---RRPPTP 861 Score = 30.8 bits (68), Expect = 3.4 Identities = 23/72 (31%), Positives = 27/72 (37%), Gaps = 12/72 (16%) Query: 504 SSPPPAPIYTPPPPAPHCPPPPP----SAPTPPIPSPPSTLPPPPQA--------PPPNR 551 S PP A + P A P PP AP P+P PP+T P P + Sbjct: 925 SPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESA 984 Query: 552 APPPSRPPPRPS 563 P P P PS Sbjct: 985 TPAPGALDPGPS 996 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.138 0.431 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,922,932 Number of Sequences: 37866 Number of extensions: 1966817 Number of successful extensions: 86427 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1321 Number of HSP's successfully gapped in prelim test: 915 Number of HSP's that attempted gapping in prelim test: 21867 Number of HSP's gapped (non-prelim): 28727 length of query: 564 length of database: 18,247,518 effective HSP length: 108 effective length of query: 456 effective length of database: 14,157,990 effective search space: 6456043440 effective search space used: 6456043440 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.