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Search of human proteins with 8922120
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8922120 crystallin, gamma S [Homo sapiens]
(178 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8922120 crystallin, gamma S [Homo sapiens] 386 e-108
gi|148491074 crystallin, gamma B [Homo sapiens] 218 3e-57
gi|10518338 crystallin, gamma C [Homo sapiens] 207 4e-54
gi|148491057 crystallin, gamma A [Homo sapiens] 203 7e-53
gi|13377002 crystallin, gamma D [Homo sapiens] 199 1e-51
gi|4758074 crystallin, beta B3 [Homo sapiens] 120 5e-28
gi|12056461 crystallin, beta A3 [Homo sapiens] 119 1e-27
gi|4503061 crystallin, beta B1 [Homo sapiens] 119 2e-27
gi|4503063 crystallin, beta B2 [Homo sapiens] 118 2e-27
gi|89886227 absent in melanoma 1-like [Homo sapiens] 107 5e-24
gi|16936542 crystallin, beta A2 [Homo sapiens] 103 6e-23
gi|16936540 crystallin, beta A2 [Homo sapiens] 103 6e-23
gi|7019357 crystallin, beta A2 [Homo sapiens] 103 6e-23
gi|4503059 crystallin, beta A4 [Homo sapiens] 99 1e-21
gi|21389517 gammaN-crystallin [Homo sapiens] 97 7e-21
gi|62988361 absent in melanoma 1 [Homo sapiens] 94 6e-20
gi|90403579 beta-gamma crystallin domain containing 3 [Homo sapi... 74 5e-14
gi|20302168 toll-like receptor 8 [Homo sapiens] 29 1.9
gi|148491070 CTP synthase [Homo sapiens] 28 3.2
gi|46909584 cAMP-dependent protein kinase catalytic subunit alph... 28 4.1
gi|4506055 cAMP-dependent protein kinase catalytic subunit alpha... 28 4.1
gi|4506057 cAMP-dependent protein kinase catalytic subunit beta ... 28 4.1
gi|46909587 cAMP-dependent protein kinase catalytic subunit beta... 28 4.1
gi|33636738 cAMP-dependent protein kinase catalytic subunit beta... 28 4.1
gi|239787086 zinc finger protein 611 isoform b [Homo sapiens] 28 5.4
gi|239787084 zinc finger protein 611 isoform a [Homo sapiens] 28 5.4
gi|239787082 zinc finger protein 611 isoform a [Homo sapiens] 28 5.4
gi|239787080 zinc finger protein 611 isoform a [Homo sapiens] 28 5.4
gi|187829640 GC-rich promoter binding protein 1 isoform 3 [Homo ... 27 7.1
gi|28875782 GC-rich promoter binding protein 1 isoform 1 [Homo s... 27 7.1
>gi|8922120 crystallin, gamma S [Homo sapiens]
Length = 178
Score = 386 bits (992), Expect = e-108
Identities = 178/178 (100%), Positives = 178/178 (100%)
Query: 1 MSKTGTKITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMY 60
MSKTGTKITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMY
Sbjct: 1 MSKTGTKITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMY 60
Query: 61 ILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIME 120
ILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIME
Sbjct: 61 ILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIME 120
Query: 121 QFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE 178
QFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE
Sbjct: 121 QFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE 178
>gi|148491074 crystallin, gamma B [Homo sapiens]
Length = 175
Score = 218 bits (554), Expect = 3e-57
Identities = 94/172 (54%), Positives = 126/172 (73%), Gaps = 1/172 (0%)
Query: 7 KITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQGE 66
KITFYED+ FQGR Y+C DC + Y SRCNSI+VE G W +YERPN+ G+ Y L +GE
Sbjct: 3 KITFYEDRAFQGRSYECTTDCPNLQPYFSRCNSIRVESGCWMIYERPNYQGHQYFLRRGE 62
Query: 67 YPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMRE 126
YP+YQ+WMGL+D + SC + P G Y+++I+++ + GQM E T+DC S+ ++FH+ E
Sbjct: 63 YPDYQQWMGLSDSIRSCCLIP-PHSGAYRMKIYDRDELRGQMSELTDDCISVQDRFHLTE 121
Query: 127 IHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE 178
IHS VLEG WI YE+PNYRGRQYLL EYR+ +DWGA + V S RR+++
Sbjct: 122 IHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMD 173
>gi|10518338 crystallin, gamma C [Homo sapiens]
Length = 174
Score = 207 bits (527), Expect = 4e-54
Identities = 92/172 (53%), Positives = 121/172 (70%), Gaps = 2/172 (1%)
Query: 7 KITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQGE 66
KITFYED+ FQGR Y+ DC + Y SRCNSI+VE G W +YERPN+ G Y+L +GE
Sbjct: 3 KITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRRGE 62
Query: 67 YPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMRE 126
YP+YQ+WMGL+D + SC + P ++++++E+ D G M E +EDCPSI ++FH+ E
Sbjct: 63 YPDYQQWMGLSDSIRSCCLI--PQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSE 120
Query: 127 IHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE 178
I S VLEG W+ YELPNYRGRQYLL +EYR+ DWGA S RR+V+
Sbjct: 121 IRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVD 172
>gi|148491057 crystallin, gamma A [Homo sapiens]
Length = 174
Score = 203 bits (516), Expect = 7e-53
Identities = 88/172 (51%), Positives = 120/172 (69%), Gaps = 2/172 (1%)
Query: 7 KITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQGE 66
KITFYED++FQGR Y+C DC + Y SRCNSI+V+ G W +YERPN+ G+ Y L +G+
Sbjct: 3 KITFYEDRDFQGRCYNCISDCPNLRVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRRGK 62
Query: 67 YPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMRE 126
YP+YQ WMGL+D + SCR + P +K++++E+ D+ G M E T+DC + E F + E
Sbjct: 63 YPDYQHWMGLSDSVQSCRII--PHTSSHKLRLYERDDYRGLMSELTDDCACVPELFRLPE 120
Query: 127 IHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE 178
I+S VLEG W+ YE+PNYRGRQYLL +YR+ DWG A V S RR+ +
Sbjct: 121 IYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLRRVTD 172
>gi|13377002 crystallin, gamma D [Homo sapiens]
Length = 174
Score = 199 bits (505), Expect = 1e-51
Identities = 86/172 (50%), Positives = 120/172 (69%), Gaps = 2/172 (1%)
Query: 7 KITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQGE 66
KIT YED+ FQGR Y+C D + YLSRCNS +V+ G W +YE+PN++G Y L +G+
Sbjct: 3 KITLYEDRGFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRRGD 62
Query: 67 YPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMRE 126
Y ++Q+WMGL+D + SCR + P G ++I+++E+ D+ GQM E TEDC + ++F E
Sbjct: 63 YADHQQWMGLSDSVRSCRLI--PHSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNE 120
Query: 127 IHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE 178
IHS VLEG W+ YEL NYRGRQYLL +YR+ DWGA + V S RR+++
Sbjct: 121 IHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVID 172
>gi|4758074 crystallin, beta B3 [Homo sapiens]
Length = 211
Score = 120 bits (302), Expect = 5e-28
Identities = 62/174 (35%), Positives = 96/174 (55%), Gaps = 5/174 (2%)
Query: 7 KITFYEDKNFQGRRYDCDCDCADF-HTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQG 65
K+ YE +NFQG+R + +C + L + SI+VE G W +E F G ++L +G
Sbjct: 25 KVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKG 84
Query: 66 EYPEYQRWMGL--NDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTED-CPSIMEQF 122
+YP + W +D L S R +++ S +K+ +FE FSG+ E +D PS+
Sbjct: 85 DYPRWDAWSNSRDSDSLLSLRPLNIDSP-HHKLHLFENPAFSGRKMEIVDDDVPSLWAHG 143
Query: 123 HMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRI 176
+ S + + G W+ YE P YRGRQY+ ++ EYR +W A+ P +QS RRI
Sbjct: 144 FQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQLQSVRRI 197
Score = 53.9 bits (128), Expect = 7e-08
Identities = 24/77 (31%), Positives = 45/77 (58%), Gaps = 1/77 (1%)
Query: 87 HLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYR 146
H GG YK+ ++E +F G+ E + +CPS+ + + ++ S +V G W+ +E +R
Sbjct: 17 HGDLGGSYKVILYELENFQGKRCELSAECPSLTDSL-LEKVGSIQVESGPWLAFESRAFR 75
Query: 147 GRQYLLDKKEYRKPIDW 163
G Q++L+K +Y + W
Sbjct: 76 GEQFVLEKGDYPRWDAW 92
>gi|12056461 crystallin, beta A3 [Homo sapiens]
Length = 215
Score = 119 bits (299), Expect = 1e-27
Identities = 66/182 (36%), Positives = 99/182 (54%), Gaps = 12/182 (6%)
Query: 7 KITFYEDKNFQGRRYDCDCDCADF-HTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQG 65
KIT Y+ +NFQG+R + C + S+KVE G W YE +F G +IL +G
Sbjct: 32 KITIYDQENFQGKRMEFTSSCPNVSERSFDNVRSLKVESGAWIGYEHTSFCGQQFILERG 91
Query: 66 EYPEYQRWMGLN----DRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQ 121
EYP + W G N +RL S R + + + K+ IFEK +F G+ +E ++D PS+
Sbjct: 92 EYPRWDAWSGSNAYHIERLMSFRPICSANHKESKMTIFEKENFIGRQWEISDDYPSLQAM 151
Query: 122 -FHMREIHSCKVLEGVWIFYELPNYRGRQYLLD----KKEYRKPIDWG--AASPAVQSFR 174
+ E+ S K+ G W+ Y+ P YRG QY+L+ +Y+ +WG A + +QS R
Sbjct: 152 GWFNNEVGSMKIQSGAWVCYQYPGYRGYQYILECDHHGGDYKHWREWGSHAQTSQIQSIR 211
Query: 175 RI 176
RI
Sbjct: 212 RI 213
Score = 55.5 bits (132), Expect = 2e-08
Identities = 29/89 (32%), Positives = 50/89 (56%), Gaps = 5/89 (5%)
Query: 92 GQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGRQYL 151
G +KI I+++ +F G+ E T CP++ E+ + S KV G WI YE ++ G+Q++
Sbjct: 29 GPWKITIYDQENFQGKRMEFTSSCPNVSER-SFDNVRSLKVESGAWIGYEHTSFCGQQFI 87
Query: 152 LDKKEYRKPIDWGAAS----PAVQSFRRI 176
L++ EY + W ++ + SFR I
Sbjct: 88 LERGEYPRWDAWSGSNAYHIERLMSFRPI 116
Score = 48.9 bits (115), Expect = 2e-06
Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 7/75 (9%)
Query: 6 TKITFYEDKNFQGRRYDCDCDCADFHT---YLSRCNSIKVEGGTWAVYERPNFAGYMYIL 62
+K+T +E +NF GR+++ D + + S+K++ G W Y+ P + GY YIL
Sbjct: 124 SKMTIFEKENFIGRQWEISDDYPSLQAMGWFNNEVGSMKIQSGAWVCYQYPGYRGYQYIL 183
Query: 63 P----QGEYPEYQRW 73
G+Y ++ W
Sbjct: 184 ECDHHGGDYKHWREW 198
>gi|4503061 crystallin, beta B1 [Homo sapiens]
Length = 252
Score = 119 bits (297), Expect = 2e-27
Identities = 64/174 (36%), Positives = 96/174 (55%), Gaps = 5/174 (2%)
Query: 7 KITFYEDKNFQGRRYDCDCDCADFHTY-LSRCNSIKVEGGTWAVYERPNFAGYMYILPQG 65
++ +E +NFQGRR + +C++ R SI V G W +E+ NF G M+IL +G
Sbjct: 60 RLVVFELENFQGRRAEFSGECSNLADRGFDRVRSIIVSAGPWVAFEQSNFRGEMFILEKG 119
Query: 66 EYPEYQRWMGL--NDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETT-EDCPSIMEQF 122
EYP + W +DRL S R + + + ++KI +FE +F G E +D PS+
Sbjct: 120 EYPRWNTWSSSYRSDRLMSFRPIKMDAQ-EHKISLFEGANFKGNTIEIQGDDAPSLWVYG 178
Query: 123 HMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRI 176
+ S KV G W+ Y+ P YRG QYLL+ ++R +WGA P +QS RR+
Sbjct: 179 FSDRVGSVKVSSGTWVGYQYPGYRGYQYLLEPGDFRHWNEWGAFQPQMQSLRRL 232
Score = 55.8 bits (133), Expect = 2e-08
Identities = 31/99 (31%), Positives = 56/99 (56%), Gaps = 4/99 (4%)
Query: 80 LSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMREIHSCKVLEGVWIF 139
++S +A LP G Y++ +FE +F G+ E + +C ++ ++ R + S V G W+
Sbjct: 46 ITSAKAAELPPGN-YRLVVFELENFQGRRAEFSGECSNLADRGFDR-VRSIIVSAGPWVA 103
Query: 140 YELPNYRGRQYLLDKKEYRKPIDWGAA--SPAVQSFRRI 176
+E N+RG ++L+K EY + W ++ S + SFR I
Sbjct: 104 FEQSNFRGEMFILEKGEYPRWNTWSSSYRSDRLMSFRPI 142
>gi|4503063 crystallin, beta B2 [Homo sapiens]
Length = 205
Score = 118 bits (296), Expect = 2e-27
Identities = 62/174 (35%), Positives = 97/174 (55%), Gaps = 5/174 (2%)
Query: 7 KITFYEDKNFQGRRYDCDCDCADF-HTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQG 65
KI +E +NFQG ++ + C + T + + S+ V+ G W YE+ N G ++ +G
Sbjct: 18 KIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWVGYEQANCKGEQFVFEKG 77
Query: 66 EYPEYQRWMGLN--DRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTED-CPSIMEQF 122
EYP + W D LSS R + + S ++KI ++E +F+G+ E +D PS
Sbjct: 78 EYPRWDSWTSSRRTDSLSSLRPIKVDSQ-EHKIILYENPNFTGKKMEIIDDDVPSFHAHG 136
Query: 123 HMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRI 176
+ ++ S +V G W+ Y+ P YRG QYLL+K +Y+ D+GA P VQS RRI
Sbjct: 137 YQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAPHPQVQSVRRI 190
>gi|89886227 absent in melanoma 1-like [Homo sapiens]
Length = 616
Score = 107 bits (267), Expect = 5e-24
Identities = 55/175 (31%), Positives = 89/175 (50%), Gaps = 8/175 (4%)
Query: 11 YEDKNFQGRRYDCDCDCADFHT-------YLSRCNSIKVEGGTWAVYERPNFAGYMYILP 63
YE FQGR ++ D + +L+ S++V GG W YE+ F G+ Y+L
Sbjct: 128 YEAPGFQGRSWEVSRDIYNLQQPEDSQSPHLASVGSLRVLGGCWVGYEKEGFRGHQYLLE 187
Query: 64 QGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFH 123
+GEYP++ W G ++ L+S R + G + +FE DF G E ++ P + H
Sbjct: 188 EGEYPDWSHWGGYDELLTSLRVIRTDFGDP-AVVLFEAMDFEGHGVEVSKALPDVELVQH 246
Query: 124 MREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE 178
+ VL GVW+ Y+ + G QY+L+K YR DWGA + + S + +++
Sbjct: 247 GPSTQAIHVLSGVWVAYQEVGFSGEQYVLEKGVYRNCEDWGAGNSTLASLQPVLQ 301
Score = 78.6 bits (192), Expect = 3e-15
Identities = 47/148 (31%), Positives = 70/148 (47%), Gaps = 10/148 (6%)
Query: 39 SIKVEGGTWAVYERPNFAGYMYILPQGEYPEYQRWMGLNDRLSSCRAVHL--PS---GGQ 93
S V G W +Y +P F YIL GEYP + W + + S + + L PS G+
Sbjct: 63 SATVSAGLWLLYPKPLFEDTPYILEPGEYPTSEAWGTSDPSVGSLKPMRLGCPSVEKPGE 122
Query: 94 YKIQIFEKGDFSGQMYETTEDC-----PSIMEQFHMREIHSCKVLEGVWIFYELPNYRGR 148
+ ++E F G+ +E + D P + H+ + S +VL G W+ YE +RG
Sbjct: 123 PRAVVYEAPGFQGRSWEVSRDIYNLQQPEDSQSPHLASVGSLRVLGGCWVGYEKEGFRGH 182
Query: 149 QYLLDKKEYRKPIDWGAASPAVQSFRRI 176
QYLL++ EY WG + S R I
Sbjct: 183 QYLLEEGEYPDWSHWGGYDELLTSLRVI 210
Score = 64.7 bits (156), Expect = 4e-11
Identities = 38/127 (29%), Positives = 61/127 (48%), Gaps = 15/127 (11%)
Query: 39 SIKVEGGTWAVYERPNFAGYMYILPQGEYPEYQRWMGLNDRLSSCRAV--------HLPS 90
+I V G W Y+ F+G Y+L +G Y + W N L+S + V H S
Sbjct: 252 AIHVLSGVWVAYQEVGFSGEQYVLEKGVYRNCEDWGAGNSTLASLQPVLQVGEHDLHFVS 311
Query: 91 GGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGRQY 150
KIQ+F + DF G + +D ++ F + SC+V G WI ++ N+ G Q+
Sbjct: 312 ----KIQLFSRPDFLGDHFSFEDDQAALPASFRPQ---SCRVHGGSWILFDETNFEGDQH 364
Query: 151 LLDKKEY 157
+L + E+
Sbjct: 365 ILSEGEF 371
Score = 59.3 bits (142), Expect = 2e-09
Identities = 44/157 (28%), Positives = 75/157 (47%), Gaps = 13/157 (8%)
Query: 6 TKITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQG 65
+KI + +F G + + D A R S +V GG+W +++ NF G +IL +G
Sbjct: 311 SKIQLFSRPDFLGDHFSFEDDQAALPASF-RPQSCRVHGGSWILFDETNFEGDQHILSEG 369
Query: 66 EYPEYQRWMG--LNDRLSSCRAVHL----PSGGQYKIQIFEKGDFSGQMYETTEDCPSIM 119
E+P MG + L S + V L PS Y ++ FE G+ E + + S+
Sbjct: 370 EFPTLTA-MGCLASTVLGSLQKVSLHFSEPSIFLYGLECFE-----GKEIELSREVRSLQ 423
Query: 120 EQFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKE 156
+ + S ++ G+W+ E ++RGRQ+L+ E
Sbjct: 424 AEGFNNHVLSVRIKGGIWVLCEHSDFRGRQWLVGSCE 460
Score = 41.2 bits (95), Expect = 5e-04
Identities = 20/80 (25%), Positives = 36/80 (45%)
Query: 95 KIQIFEKGDFSGQMYETTEDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDK 154
+I +F + G+ + TE + ++ S V G+W+ Y P + Y+L+
Sbjct: 29 EISLFSEEGLKGEQVKLTEALKNSQGLEKPLQVASATVSAGLWLLYPKPLFEDTPYILEP 88
Query: 155 KEYRKPIDWGAASPAVQSFR 174
EY WG + P+V S +
Sbjct: 89 GEYPTSEAWGTSDPSVGSLK 108
>gi|16936542 crystallin, beta A2 [Homo sapiens]
Length = 197
Score = 103 bits (258), Expect = 6e-23
Identities = 52/157 (33%), Positives = 88/157 (56%), Gaps = 7/157 (4%)
Query: 8 ITFYEDKNFQGRRYDCDCDCADF--HTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQG 65
+T +++++FQGRR DCA+ L R S+KVE G W +E P+F G +IL +G
Sbjct: 14 LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73
Query: 66 EYPEYQRWMGL----NDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQ 121
+YP + W G +++L S R V + ++ +FE +F G ++ +D PS+
Sbjct: 74 DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSM 133
Query: 122 -FHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEY 157
+ +++ S KV G W+ Y+ P YRG QY+L++ +
Sbjct: 134 GWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRH 170
Score = 56.6 bits (135), Expect = 1e-08
Identities = 22/79 (27%), Positives = 45/79 (56%)
Query: 89 PSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGR 148
P + ++++ DF G+ DC ++ E+ + + S KV GVW+ +E P+++G+
Sbjct: 7 PGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQ 66
Query: 149 QYLLDKKEYRKPIDWGAAS 167
Q++L+K +Y + W +S
Sbjct: 67 QFILEKGDYPRWSAWSGSS 85
Score = 43.5 bits (101), Expect = 1e-04
Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 7/72 (9%)
Query: 6 TKITFYEDKNFQGRRYDCDCDCADFHT--YLSR-CNSIKVEGGTWAVYERPNFAGYMYIL 62
+++T +E NFQG ++D D + + S+ S+KV G W Y+ P + GY Y+L
Sbjct: 106 SRVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVL 165
Query: 63 PQ----GEYPEY 70
+ GE+ Y
Sbjct: 166 ERDRHSGEFCTY 177
>gi|16936540 crystallin, beta A2 [Homo sapiens]
Length = 197
Score = 103 bits (258), Expect = 6e-23
Identities = 52/157 (33%), Positives = 88/157 (56%), Gaps = 7/157 (4%)
Query: 8 ITFYEDKNFQGRRYDCDCDCADF--HTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQG 65
+T +++++FQGRR DCA+ L R S+KVE G W +E P+F G +IL +G
Sbjct: 14 LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73
Query: 66 EYPEYQRWMGL----NDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQ 121
+YP + W G +++L S R V + ++ +FE +F G ++ +D PS+
Sbjct: 74 DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSM 133
Query: 122 -FHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEY 157
+ +++ S KV G W+ Y+ P YRG QY+L++ +
Sbjct: 134 GWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRH 170
Score = 56.6 bits (135), Expect = 1e-08
Identities = 22/79 (27%), Positives = 45/79 (56%)
Query: 89 PSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGR 148
P + ++++ DF G+ DC ++ E+ + + S KV GVW+ +E P+++G+
Sbjct: 7 PGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQ 66
Query: 149 QYLLDKKEYRKPIDWGAAS 167
Q++L+K +Y + W +S
Sbjct: 67 QFILEKGDYPRWSAWSGSS 85
Score = 43.5 bits (101), Expect = 1e-04
Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 7/72 (9%)
Query: 6 TKITFYEDKNFQGRRYDCDCDCADFHT--YLSR-CNSIKVEGGTWAVYERPNFAGYMYIL 62
+++T +E NFQG ++D D + + S+ S+KV G W Y+ P + GY Y+L
Sbjct: 106 SRVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVL 165
Query: 63 PQ----GEYPEY 70
+ GE+ Y
Sbjct: 166 ERDRHSGEFCTY 177
>gi|7019357 crystallin, beta A2 [Homo sapiens]
Length = 197
Score = 103 bits (258), Expect = 6e-23
Identities = 52/157 (33%), Positives = 88/157 (56%), Gaps = 7/157 (4%)
Query: 8 ITFYEDKNFQGRRYDCDCDCADF--HTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQG 65
+T +++++FQGRR DCA+ L R S+KVE G W +E P+F G +IL +G
Sbjct: 14 LTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQQFILEKG 73
Query: 66 EYPEYQRWMGL----NDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQ 121
+YP + W G +++L S R V + ++ +FE +F G ++ +D PS+
Sbjct: 74 DYPRWSAWSGSSSHNSNQLLSFRPVLCANHNDSRVTLFEGDNFQGCKFDLVDDYPSLPSM 133
Query: 122 -FHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEY 157
+ +++ S KV G W+ Y+ P YRG QY+L++ +
Sbjct: 134 GWASKDVGSLKVSSGAWVAYQYPGYRGYQYVLERDRH 170
Score = 56.6 bits (135), Expect = 1e-08
Identities = 22/79 (27%), Positives = 45/79 (56%)
Query: 89 PSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGR 148
P + ++++ DF G+ DC ++ E+ + + S KV GVW+ +E P+++G+
Sbjct: 7 PGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGLPRVRSVKVENGVWVAFEYPDFQGQ 66
Query: 149 QYLLDKKEYRKPIDWGAAS 167
Q++L+K +Y + W +S
Sbjct: 67 QFILEKGDYPRWSAWSGSS 85
Score = 43.5 bits (101), Expect = 1e-04
Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 7/72 (9%)
Query: 6 TKITFYEDKNFQGRRYDCDCDCADFHT--YLSR-CNSIKVEGGTWAVYERPNFAGYMYIL 62
+++T +E NFQG ++D D + + S+ S+KV G W Y+ P + GY Y+L
Sbjct: 106 SRVTLFEGDNFQGCKFDLVDDYPSLPSMGWASKDVGSLKVSSGAWVAYQYPGYRGYQYVL 165
Query: 63 PQ----GEYPEY 70
+ GE+ Y
Sbjct: 166 ERDRHSGEFCTY 177
>gi|4503059 crystallin, beta A4 [Homo sapiens]
Length = 196
Score = 99.4 bits (246), Expect = 1e-21
Identities = 59/182 (32%), Positives = 92/182 (50%), Gaps = 12/182 (6%)
Query: 7 KITFYEDKNFQGRRYDCDCDCAD-FHTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQG 65
K+ +++ FQGRR++ +C S+KV G W +E F G YIL +G
Sbjct: 13 KMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEHAGFQGQQYILERG 72
Query: 66 EYPEYQRWMGLN----DRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQ 121
EYP + W G +RL+S R + ++ IFE+ +F G+ E ++D PS+
Sbjct: 73 EYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKGELSDDYPSLQAM 132
Query: 122 -FHMREIHSCKVLEGVWIFYELPNYRGRQYLLD----KKEYRKPIDWGAASPA--VQSFR 174
+ E+ S V G W+ + P YRG QY+L+ +Y+ +WG+ +P VQS R
Sbjct: 133 GWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWGSHAPTFQVQSIR 192
Query: 175 RI 176
RI
Sbjct: 193 RI 194
Score = 62.0 bits (149), Expect = 3e-10
Identities = 32/89 (35%), Positives = 53/89 (59%), Gaps = 5/89 (5%)
Query: 90 SGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGRQ 149
S G +K+ ++++ F G+ +E T +CPS++E + S KVL G W+ +E ++G+Q
Sbjct: 8 SAGPWKMVVWDEDGFQGRRHEFTAECPSVLE-LGFETVRSLKVLSGAWVGFEHAGFQGQQ 66
Query: 150 YLLDKKEYRKPIDWG--AASPA--VQSFR 174
Y+L++ EY WG A PA + SFR
Sbjct: 67 YILERGEYPSWDAWGGNTAYPAERLTSFR 95
>gi|21389517 gammaN-crystallin [Homo sapiens]
Length = 182
Score = 97.1 bits (240), Expect = 7e-21
Identities = 46/123 (37%), Positives = 73/123 (59%), Gaps = 3/123 (2%)
Query: 1 MSKTGTKITFYEDKNFQGRRYDCDCDCADFHT--YLSRCNSIKVEGGTWAVYERPNFAGY 58
M++ KIT YE K+F G++ + DC +F +++R NSI VE G W + P+F G
Sbjct: 1 MAQRSGKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQ 60
Query: 59 MYILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSI 118
+IL G+YP++ RW +D + SCR V + G ++++IFE +F+GQ E ED P +
Sbjct: 61 QFILEHGDYPDFFRWNSHSDHMGSCRPVGM-HGEHFRLEIFEGCNFTGQCLEFLEDSPFL 119
Query: 119 MEQ 121
+
Sbjct: 120 QSR 122
Score = 53.9 bits (128), Expect = 7e-08
Identities = 24/82 (29%), Positives = 44/82 (53%)
Query: 95 KIQIFEKGDFSGQMYETTEDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDK 154
KI ++E F+GQ E DC + ++ M ++S V G W+ + P++RG+Q++L+
Sbjct: 7 KITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQQFILEH 66
Query: 155 KEYRKPIDWGAASPAVQSFRRI 176
+Y W + S + S R +
Sbjct: 67 GDYPDFFRWNSHSDHMGSCRPV 88
>gi|62988361 absent in melanoma 1 [Homo sapiens]
Length = 1723
Score = 94.0 bits (232), Expect = 6e-20
Identities = 56/188 (29%), Positives = 84/188 (44%), Gaps = 15/188 (7%)
Query: 4 TGTKITFYEDKNFQGRRYDCDCDCADF--------------HTYLSRCNSIKVEGGTWAV 49
T K+ YE F+G+ + + F H + S+KV G W
Sbjct: 1216 TDPKVVVYEKPFFEGKCVELETGMCSFVMEGGETEEATGDDHLPFTSVGSMKVLRGIWVA 1275
Query: 50 YERPNFAGYMYILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFS-GQM 108
YE+P F G+ Y+L +GEY +++ W G N L S R + + I EK S G
Sbjct: 1276 YEKPGFTGHQYLLEEGEYRDWKAWGGYNGELQSLRPILGDFSNAHMIMYSEKNFGSKGSS 1335
Query: 109 YETTEDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASP 168
+ ++ E + + S VL GVW+ YE P++ G QY+LDK Y DWG +
Sbjct: 1336 IDVLGIVANLKETGYGVKTQSINVLSGVWVAYENPDFTGEQYILDKGFYTSFEDWGGKNC 1395
Query: 169 AVQSFRRI 176
+ S + I
Sbjct: 1396 KISSVQPI 1403
Score = 89.7 bits (221), Expect = 1e-18
Identities = 56/158 (35%), Positives = 78/158 (49%), Gaps = 21/158 (13%)
Query: 39 SIKVEGGTWAVYERPNFAGYMYILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQY---- 94
S+KV GTW +YE P F G +IL GEYP+ W + S R + + GG+
Sbjct: 1158 SMKVHWGTWLIYEEPGFQGVPFILEPGEYPDLSFWDTEAAYIGSMRPLKM--GGRKVEFP 1215
Query: 95 ---KIQIFEKGDFSGQMYET-TEDCPSIMEQFHMRE-----------IHSCKVLEGVWIF 139
K+ ++EK F G+ E T C +ME E + S KVL G+W+
Sbjct: 1216 TDPKVVVYEKPFFEGKCVELETGMCSFVMEGGETEEATGDDHLPFTSVGSMKVLRGIWVA 1275
Query: 140 YELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIV 177
YE P + G QYLL++ EYR WG + +QS R I+
Sbjct: 1276 YEKPGFTGHQYLLEEGEYRDWKAWGGYNGELQSLRPIL 1313
Score = 77.8 bits (190), Expect = 5e-15
Identities = 49/155 (31%), Positives = 74/155 (47%), Gaps = 11/155 (7%)
Query: 11 YEDKNF--QGRRYDCDCDCADFHT--YLSRCNSIKVEGGTWAVYERPNFAGYMYILPQGE 66
Y +KNF +G D A+ Y + SI V G W YE P+F G YIL +G
Sbjct: 1324 YSEKNFGSKGSSIDVLGIVANLKETGYGVKTQSINVLSGVWVAYENPDFTGEQYILDKGF 1383
Query: 67 YPEYQRWMGLNDRLSSCRAVHLPS----GGQYKIQIFEKGDFSGQMYETTEDCPSIMEQF 122
Y ++ W G N ++SS + + L S + +I +F + F G E I + F
Sbjct: 1384 YTSFEDWGGKNCKISSVQPICLDSFTGPRRRNQIHLFSEPQFQGHSQSFEETTSQIDDSF 1443
Query: 123 HMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEY 157
+ SC+V G W+ Y+ N+ G QY+L++ Y
Sbjct: 1444 STK---SCRVSGGSWVVYDGENFTGNQYVLEEGHY 1475
Score = 74.3 bits (181), Expect = 5e-14
Identities = 46/163 (28%), Positives = 71/163 (43%), Gaps = 27/163 (16%)
Query: 7 KITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQGE 66
+I + + FQG + + S S +V GG+W VY+ NF G Y+L +G
Sbjct: 1416 QIHLFSEPQFQGHSQSFEETTSQIDDSFST-KSCRVSGGSWVVYDGENFTGNQYVLEEGH 1474
Query: 67 YPEYQRWMGLNDRLSSCRAVHLPSGGQYK-------------IQIFEKGDFSGQMYETTE 113
YP A+ P G +K I +FE+ DF G+ E
Sbjct: 1475 YP-------------CLSAMGCPPGATFKSLRFIDVEFSEPTIILFEREDFKGKKIELNA 1521
Query: 114 DCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKE 156
+ ++ +I S +V+ G+W+ YE +YRGRQ+LL E
Sbjct: 1522 ETVNLRSLGFNTQIRSVQVIGGIWVTYEYGSYRGRQFLLSPAE 1564
Score = 53.9 bits (128), Expect = 7e-08
Identities = 48/182 (26%), Positives = 79/182 (43%), Gaps = 15/182 (8%)
Query: 7 KITFYEDKNFQGRRYDCDCDCADFHTY-LSRCNSIKVEGGTWAVYERPNFAGYMYILPQG 65
K+ Y + + + + D D ++ LS IKV G W +YE+PNF G+ L +G
Sbjct: 1023 KVVIYSEPDVSEKCIEVFSDIQDCSSWSLSPVILIKVVRGCWILYEQPNFEGHSIPLEEG 1082
Query: 66 EYPEYQRWMGLNDRLS------SCRAVHLPS----GGQYK---IQIFEKGDFSGQMYETT 112
E W G+ D L S + V + S Y+ I +F + + G +
Sbjct: 1083 ELELSGLW-GIEDILERHEEAESDKPVVIGSIRHVVQDYRVSHIDLFTEPEGLGILSSYF 1141
Query: 113 EDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQS 172
+D + M++ S KV G W+ YE P ++G ++L+ EY W + + S
Sbjct: 1142 DDTEEMQGFGVMQKTCSMKVHWGTWLIYEEPGFQGVPFILEPGEYPDLSFWDTEAAYIGS 1201
Query: 173 FR 174
R
Sbjct: 1202 MR 1203
Score = 39.7 bits (91), Expect = 0.001
Identities = 16/70 (22%), Positives = 38/70 (54%), Gaps = 2/70 (2%)
Query: 8 ITFYEDKNFQGRRYDCDCDCADFHT--YLSRCNSIKVEGGTWAVYERPNFAGYMYILPQG 65
I +E ++F+G++ + + + + + + ++ S++V GG W YE ++ G ++L
Sbjct: 1504 IILFEREDFKGKKIELNAETVNLRSLGFNTQIRSVQVIGGIWVTYEYGSYRGRQFLLSPA 1563
Query: 66 EYPEYQRWMG 75
E P + + G
Sbjct: 1564 EVPNWYEFSG 1573
>gi|90403579 beta-gamma crystallin domain containing 3 [Homo
sapiens]
Length = 1022
Score = 74.3 bits (181), Expect = 5e-14
Identities = 47/177 (26%), Positives = 83/177 (46%), Gaps = 8/177 (4%)
Query: 7 KITFYEDKNFQGRRYDCDCDCADFHTYLS------RCNSIKVEGGTWAVYERPNFAGYMY 60
K+ YE +F G+ + +L R SI+V GG W YE+ +F G +
Sbjct: 532 KVIIYEKPHFHGQAKEFSEHIDSVPNFLKNNGDFHRIGSIRVIGGVWVAYEKEHFKGQQF 591
Query: 61 ILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIME 120
+L +G++ + L+ + S R + + + + +FE SG+ + T S +E
Sbjct: 592 LLEEGDFEDSNACGALSSPILSFRYLQA-NFIESSVTLFESDLESGKFIDITNQEISDLE 650
Query: 121 QFHM-REIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRI 176
+ + S V GVW+ Y+ + G QY+L+K +Y+ DWG ++ + S R I
Sbjct: 651 EIGFGSKTRSIHVKSGVWVAYQQKFFCGEQYILEKGKYKCFFDWGGSNNIIMSIRPI 707
Score = 60.8 bits (146), Expect = 6e-10
Identities = 40/146 (27%), Positives = 65/146 (44%), Gaps = 8/146 (5%)
Query: 35 SRCNSIKVEGGTWAVYERPNFAGYMYILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGG-- 92
S+ SI V+ G W Y++ F G YIL +G+Y + W G N+ + S R + L G
Sbjct: 656 SKTRSIHVKSGVWVAYQQKFFCGEQYILEKGKYKCFFDWGGSNNIIMSIRPIQLEPLGIN 715
Query: 93 --QYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGRQY 150
+ ++ F K F G+ + TE+ + S KVL G W+ Y +
Sbjct: 716 EPPHLLKAFSKPGFQGECIDFTEETSDLTSLMPC----SFKVLRGCWLLYYQEDMFVNHC 771
Query: 151 LLDKKEYRKPIDWGAASPAVQSFRRI 176
+L++ Y G + V+S + I
Sbjct: 772 VLEEGLYADLTSCGCPASKVKSLKPI 797
Score = 59.3 bits (142), Expect = 2e-09
Identities = 46/156 (29%), Positives = 73/156 (46%), Gaps = 25/156 (16%)
Query: 34 LSRCNSIKVEGGTWAVYERPNFAGYMYILPQGEYPEYQRWMGLND-RLSSCRAVH-LPSG 91
+S+ S V+ G W Y NF G +L + GL + + +++H L G
Sbjct: 470 ISKSVSFTVKSGVWLAYPDINFKGQATVLEEDH--------GLFEISTAEMKSLHPLQMG 521
Query: 92 G-------QYKIQIFEKGDFSGQMYETTEDCPSIME------QFHMREIHSCKVLEGVWI 138
G K+ I+EK F GQ E +E S+ FH I S +V+ GVW+
Sbjct: 522 GLKVEMPMNLKVIIYEKPHFHGQAKEFSEHIDSVPNFLKNNGDFH--RIGSIRVIGGVWV 579
Query: 139 FYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFR 174
YE +++G+Q+LL++ ++ GA S + SFR
Sbjct: 580 AYEKEHFKGQQFLLEEGDFEDSNACGALSSPILSFR 615
Score = 44.7 bits (104), Expect = 4e-05
Identities = 34/122 (27%), Positives = 60/122 (49%), Gaps = 9/122 (7%)
Query: 40 IKVEGGTWAVYERPNFAGYMYILPQGEYPEYQRWMGLNDR-------LSSCRAVHLPSGG 92
IKV G W +YE+P+F G +L +GE + W+ N R L S + V L
Sbjct: 381 IKVVRGCWILYEKPHFRGQKCVLEEGEKVLNRDWILQNRRHPQRNFILGSLKRV-LKDCS 439
Query: 93 QYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGRQYLL 152
+I++F + D + P+ +E+ ++ + S V GVW+ Y N++G+ +L
Sbjct: 440 IPEIELFPQSDPACCPVYIQRAVPN-LEELNISKSVSFTVKSGVWLAYPDINFKGQATVL 498
Query: 153 DK 154
++
Sbjct: 499 EE 500
Score = 37.0 bits (84), Expect = 0.009
Identities = 37/146 (25%), Positives = 58/146 (39%), Gaps = 3/146 (2%)
Query: 11 YEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQGEYPEY 70
+ FQG D + +D T L C S KV G W +Y + + +L +G Y +
Sbjct: 724 FSKPGFQGECIDFTEETSDL-TSLMPC-SFKVLRGCWLLYYQEDMFVNHCVLEEGLYADL 781
Query: 71 QRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIMEQFHMREIHSC 130
++ S + + + I +F G+ E S++ + S
Sbjct: 782 TSCGCPASKVKSLKPIDYVFE-EPSISLFALEHCEGRELHLEEAVNSVLNKDLHFYTQSV 840
Query: 131 KVLEGVWIFYELPNYRGRQYLLDKKE 156
V G+WI YE N+ GRQ LL E
Sbjct: 841 WVKSGLWIAYEGSNFLGRQILLRPNE 866
Score = 34.7 bits (78), Expect = 0.044
Identities = 14/33 (42%), Positives = 22/33 (66%)
Query: 131 KVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDW 163
KV+ G WI YE P++RG++ +L++ E DW
Sbjct: 382 KVVRGCWILYEKPHFRGQKCVLEEGEKVLNRDW 414
Score = 31.6 bits (70), Expect = 0.38
Identities = 17/48 (35%), Positives = 21/48 (43%), Gaps = 6/48 (12%)
Query: 29 DFHTYLSRCNSIKVEGGTWAVYERPNFAGYMYILPQGEYPE---YQRW 73
D H Y S+ V+ G W YE NF G +L E P + RW
Sbjct: 832 DLHFYTQ---SVWVKSGLWIAYEGSNFLGRQILLRPNEIPNWTAFSRW 876
>gi|20302168 toll-like receptor 8 [Homo sapiens]
Length = 1041
Score = 29.3 bits (64), Expect = 1.9
Identities = 12/41 (29%), Positives = 22/41 (53%), Gaps = 3/41 (7%)
Query: 2 SKTGTKITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKV 42
+KT TK++ E G ++C CD DF ++ ++K+
Sbjct: 758 TKTTTKLSMLE---LHGNPFECTCDIGDFRRWMDEHLNVKI 795
>gi|148491070 CTP synthase [Homo sapiens]
Length = 591
Score = 28.5 bits (62), Expect = 3.2
Identities = 21/92 (22%), Positives = 43/92 (46%), Gaps = 11/92 (11%)
Query: 40 IKVEGGTWAVYERPNFAGYMYILPQG-----EYPEYQRWMGLNDRLSSCRAVHLPSGGQY 94
I ++ GT++ YE G +++L G + Y+R++ + RL+ + QY
Sbjct: 43 INIDAGTFSPYEH----GEVFVLDDGGEVDLDLGNYERFLDI--RLTKDNNLTTGKIYQY 96
Query: 95 KIQIFEKGDFSGQMYETTEDCPSIMEQFHMRE 126
I KGD+ G+ + ++++ MR+
Sbjct: 97 VINKERKGDYLGKTVQVVPHITDAIQEWVMRQ 128
>gi|46909584 cAMP-dependent protein kinase catalytic subunit alpha
isoform 2 [Homo sapiens]
Length = 343
Score = 28.1 bits (61), Expect = 4.1
Identities = 18/61 (29%), Positives = 27/61 (44%), Gaps = 1/61 (1%)
Query: 41 KVEGGTWAVYERPNFAGYMYILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFE 100
+V+G TW + P + IL +G Y + W L + A + P IQI+E
Sbjct: 183 RVKGRTWTLCGTPEYLAPEIILSKG-YNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYE 241
Query: 101 K 101
K
Sbjct: 242 K 242
>gi|4506055 cAMP-dependent protein kinase catalytic subunit alpha
isoform 1 [Homo sapiens]
Length = 351
Score = 28.1 bits (61), Expect = 4.1
Identities = 18/61 (29%), Positives = 27/61 (44%), Gaps = 1/61 (1%)
Query: 41 KVEGGTWAVYERPNFAGYMYILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFE 100
+V+G TW + P + IL +G Y + W L + A + P IQI+E
Sbjct: 191 RVKGRTWTLCGTPEYLAPEIILSKG-YNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYE 249
Query: 101 K 101
K
Sbjct: 250 K 250
>gi|4506057 cAMP-dependent protein kinase catalytic subunit beta
isoform 2 [Homo sapiens]
Length = 351
Score = 28.1 bits (61), Expect = 4.1
Identities = 18/61 (29%), Positives = 27/61 (44%), Gaps = 1/61 (1%)
Query: 41 KVEGGTWAVYERPNFAGYMYILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFE 100
+V+G TW + P + IL +G Y + W L + A + P IQI+E
Sbjct: 191 RVKGRTWTLCGTPEYLAPEIILSKG-YNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYE 249
Query: 101 K 101
K
Sbjct: 250 K 250
>gi|46909587 cAMP-dependent protein kinase catalytic subunit beta
isoform 3 [Homo sapiens]
Length = 257
Score = 28.1 bits (61), Expect = 4.1
Identities = 18/61 (29%), Positives = 27/61 (44%), Gaps = 1/61 (1%)
Query: 41 KVEGGTWAVYERPNFAGYMYILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFE 100
+V+G TW + P + IL +G Y + W L + A + P IQI+E
Sbjct: 191 RVKGRTWTLCGTPEYLAPEIILSKG-YNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYE 249
Query: 101 K 101
K
Sbjct: 250 K 250
>gi|33636738 cAMP-dependent protein kinase catalytic subunit beta
isoform 1 [Homo sapiens]
Length = 398
Score = 28.1 bits (61), Expect = 4.1
Identities = 18/61 (29%), Positives = 27/61 (44%), Gaps = 1/61 (1%)
Query: 41 KVEGGTWAVYERPNFAGYMYILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFE 100
+V+G TW + P + IL +G Y + W L + A + P IQI+E
Sbjct: 238 RVKGRTWTLCGTPEYLAPEIILSKG-YNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYE 296
Query: 101 K 101
K
Sbjct: 297 K 297
>gi|239787086 zinc finger protein 611 isoform b [Homo sapiens]
Length = 636
Score = 27.7 bits (60), Expect = 5.4
Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 6/44 (13%)
Query: 76 LNDRLSSCRAVHLPSGGQYKIQIFE-KGDFSGQMYETTEDCPSI 118
+ D+L S HLP ++ IF+ KG+ Q+ ++T D PS+
Sbjct: 83 IKDQLGSSFYSHLP-----ELHIFQIKGEIGNQLEKSTNDAPSV 121
>gi|239787084 zinc finger protein 611 isoform a [Homo sapiens]
Length = 705
Score = 27.7 bits (60), Expect = 5.4
Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 6/44 (13%)
Query: 76 LNDRLSSCRAVHLPSGGQYKIQIFE-KGDFSGQMYETTEDCPSI 118
+ D+L S HLP ++ IF+ KG+ Q+ ++T D PS+
Sbjct: 152 IKDQLGSSFYSHLP-----ELHIFQIKGEIGNQLEKSTNDAPSV 190
>gi|239787082 zinc finger protein 611 isoform a [Homo sapiens]
Length = 705
Score = 27.7 bits (60), Expect = 5.4
Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 6/44 (13%)
Query: 76 LNDRLSSCRAVHLPSGGQYKIQIFE-KGDFSGQMYETTEDCPSI 118
+ D+L S HLP ++ IF+ KG+ Q+ ++T D PS+
Sbjct: 152 IKDQLGSSFYSHLP-----ELHIFQIKGEIGNQLEKSTNDAPSV 190
>gi|239787080 zinc finger protein 611 isoform a [Homo sapiens]
Length = 705
Score = 27.7 bits (60), Expect = 5.4
Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 6/44 (13%)
Query: 76 LNDRLSSCRAVHLPSGGQYKIQIFE-KGDFSGQMYETTEDCPSI 118
+ D+L S HLP ++ IF+ KG+ Q+ ++T D PS+
Sbjct: 152 IKDQLGSSFYSHLP-----ELHIFQIKGEIGNQLEKSTNDAPSV 190
>gi|187829640 GC-rich promoter binding protein 1 isoform 3 [Homo
sapiens]
Length = 480
Score = 27.3 bits (59), Expect = 7.1
Identities = 14/49 (28%), Positives = 23/49 (46%)
Query: 113 EDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPI 161
ED PS+ ++ H+ + GVW + P R + L+ KK K +
Sbjct: 142 EDFPSLNPEYEREPNHNKSLAAGVWEYPPNPKSRAPRMLVIKKGNTKDL 190
>gi|28875782 GC-rich promoter binding protein 1 isoform 1 [Homo
sapiens]
Length = 473
Score = 27.3 bits (59), Expect = 7.1
Identities = 14/49 (28%), Positives = 23/49 (46%)
Query: 113 EDCPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPI 161
ED PS+ ++ H+ + GVW + P R + L+ KK K +
Sbjct: 135 EDFPSLNPEYEREPNHNKSLAAGVWEYPPNPKSRAPRMLVIKKGNTKDL 183
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.139 0.456
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,544,816
Number of Sequences: 37866
Number of extensions: 342154
Number of successful extensions: 650
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 523
Number of HSP's gapped (non-prelim): 59
length of query: 178
length of database: 18,247,518
effective HSP length: 96
effective length of query: 82
effective length of database: 14,612,382
effective search space: 1198215324
effective search space used: 1198215324
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.