Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 88759348
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|88759348 ring finger protein 219 [Homo sapiens]
(726 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|88759348 ring finger protein 219 [Homo sapiens] 1447 0.0
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 69 2e-11
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 55 2e-07
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 55 3e-07
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 55 3e-07
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 53 1e-06
gi|38570058 hypothetical protein LOC80129 [Homo sapiens] 52 1e-06
gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens] 52 3e-06
gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens] 52 3e-06
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 51 4e-06
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 50 6e-06
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 50 7e-06
gi|118498362 kinectin 1 isoform b [Homo sapiens] 49 2e-05
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 49 2e-05
gi|42794779 myosin 18A isoform b [Homo sapiens] 49 2e-05
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 48 3e-05
gi|122891870 melanoma inhibitory activity family, member 3 [Homo... 48 4e-05
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens] 48 4e-05
gi|158186614 transmembrane protein 118 isoform 1 [Homo sapiens] 48 4e-05
gi|109134327 PTD016 protein [Homo sapiens] 47 5e-05
gi|118498356 kinectin 1 isoform a [Homo sapiens] 47 6e-05
gi|118498368 kinectin 1 isoform c [Homo sapiens] 47 6e-05
gi|33620775 kinectin 1 isoform a [Homo sapiens] 47 6e-05
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 47 6e-05
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 47 8e-05
gi|110347443 TATA element modulatory factor 1 [Homo sapiens] 47 8e-05
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 47 8e-05
gi|190194355 p90 autoantigen [Homo sapiens] 46 1e-04
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 46 1e-04
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 46 1e-04
>gi|88759348 ring finger protein 219 [Homo sapiens]
Length = 726
Score = 1447 bits (3745), Expect = 0.0
Identities = 726/726 (100%), Positives = 726/726 (100%)
Query: 1 MAQTVQNVTLSLTLPITCHICLGKVRQPVICINNHVFCSICIDLWLKNNSQCPACRVPIT 60
MAQTVQNVTLSLTLPITCHICLGKVRQPVICINNHVFCSICIDLWLKNNSQCPACRVPIT
Sbjct: 1 MAQTVQNVTLSLTLPITCHICLGKVRQPVICINNHVFCSICIDLWLKNNSQCPACRVPIT 60
Query: 61 PENPCKEIIGGTSESEPMLSHTVRKHLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSL 120
PENPCKEIIGGTSESEPMLSHTVRKHLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSL
Sbjct: 61 PENPCKEIIGGTSESEPMLSHTVRKHLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSL 120
Query: 121 ESQIKTILDPLTLVQGNQNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDK 180
ESQIKTILDPLTLVQGNQNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDK
Sbjct: 121 ESQIKTILDPLTLVQGNQNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDK 180
Query: 181 LKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKAL 240
LKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKAL
Sbjct: 181 LKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKAL 240
Query: 241 ERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARK 300
ERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARK
Sbjct: 241 ERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARK 300
Query: 301 QPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLDVTDTSM 360
QPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLDVTDTSM
Sbjct: 301 QPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLDVTDTSM 360
Query: 361 DTYLEREWGNKPSDCVPYKDEELYDLPAPCTPLSLSCLQLSTPENRESSVVQAGGSKKHS 420
DTYLEREWGNKPSDCVPYKDEELYDLPAPCTPLSLSCLQLSTPENRESSVVQAGGSKKHS
Sbjct: 361 DTYLEREWGNKPSDCVPYKDEELYDLPAPCTPLSLSCLQLSTPENRESSVVQAGGSKKHS 420
Query: 421 NHLRKLVFDDFCDSSNVSNKDSSEDDISRSENEKKSECFSSPKTGFWDCCSTSYAQNLDF 480
NHLRKLVFDDFCDSSNVSNKDSSEDDISRSENEKKSECFSSPKTGFWDCCSTSYAQNLDF
Sbjct: 421 NHLRKLVFDDFCDSSNVSNKDSSEDDISRSENEKKSECFSSPKTGFWDCCSTSYAQNLDF 480
Query: 481 ESSEGNTIANSVGEISSKLSEKSGLCLSKRLNSIRSFEMNRTRTSSEASMDAAYLDKISE 540
ESSEGNTIANSVGEISSKLSEKSGLCLSKRLNSIRSFEMNRTRTSSEASMDAAYLDKISE
Sbjct: 481 ESSEGNTIANSVGEISSKLSEKSGLCLSKRLNSIRSFEMNRTRTSSEASMDAAYLDKISE 540
Query: 541 LDSMMSESDNSKSPCNNGFKSLDLDGLSKSSQGSEFLEEPDKLEEKTELNLSKGSLTNDQ 600
LDSMMSESDNSKSPCNNGFKSLDLDGLSKSSQGSEFLEEPDKLEEKTELNLSKGSLTNDQ
Sbjct: 541 LDSMMSESDNSKSPCNNGFKSLDLDGLSKSSQGSEFLEEPDKLEEKTELNLSKGSLTNDQ 600
Query: 601 LENGSEWKPTSFFLLSPSDQEMNEDFSLHSSSCPVTNEIKPPSCLFQTEFSQGILLSSSH 660
LENGSEWKPTSFFLLSPSDQEMNEDFSLHSSSCPVTNEIKPPSCLFQTEFSQGILLSSSH
Sbjct: 601 LENGSEWKPTSFFLLSPSDQEMNEDFSLHSSSCPVTNEIKPPSCLFQTEFSQGILLSSSH 660
Query: 661 RLFEDQRFGSSLFKMSSEMHSLHNHLQSPWSTSFVPEKRNKNVNQSTKRKIQSSLSSASP 720
RLFEDQRFGSSLFKMSSEMHSLHNHLQSPWSTSFVPEKRNKNVNQSTKRKIQSSLSSASP
Sbjct: 661 RLFEDQRFGSSLFKMSSEMHSLHNHLQSPWSTSFVPEKRNKNVNQSTKRKIQSSLSSASP 720
Query: 721 SKATKS 726
SKATKS
Sbjct: 721 SKATKS 726
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 68.9 bits (167), Expect = 2e-11
Identities = 84/374 (22%), Positives = 145/374 (38%), Gaps = 10/374 (2%)
Query: 259 NSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARKQPGSSTSSSSHLAKPS-S 317
NSS+ ++ NS ++ S+D S S + S N DS+ S +S SS+ + + S
Sbjct: 730 NSSDSSDSSNS-SDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDS 788
Query: 318 SRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLDVTDTSMDTYLEREWGNKPSDCVP 377
S D+S + S S + S + D D +++S + + + SD
Sbjct: 789 SNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS--DSSNSSDSSDSSD 846
Query: 378 YKDEELYDLPAPCTPLSLSCLQLSTPENRESSVVQAGGSKKHSNHLRKLVFDDFCDSSNV 437
D D + S S+ + S + S + SN D DSSN
Sbjct: 847 SSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNS------SDSSDSSNS 900
Query: 438 SNKDSSEDDISRSENEKKSECFSSPKTGFWDCCSTSYAQNLDFESSEGNTIANSVGEISS 497
S+ DSS+ S ++ + SS + D ++S + N S ++ +S SS
Sbjct: 901 SDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSS 960
Query: 498 KLSEKSGLCLSKRLNSIRSFEMNRTRTSSEASMDAAYLDKISELDSMMSESDNSKSPCNN 557
S S S +S S + + SS++S + D + DS S + S ++
Sbjct: 961 DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD 1020
Query: 558 GFKSLDLDGLSKSSQGSEFLEEPDKLEEKTELNLSKGSLTNDQLENGSEWKPTSFFLLSP 617
S D S SS S+ + D + + S S ++D ++ + S
Sbjct: 1021 SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1080
Query: 618 SDQEMNEDFSLHSS 631
S + + S +SS
Sbjct: 1081 SSESSDSSDSSNSS 1094
Score = 68.2 bits (165), Expect = 3e-11
Identities = 87/395 (22%), Positives = 156/395 (39%), Gaps = 12/395 (3%)
Query: 241 ERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARK 300
+ SD + +S ++ +S + ++ +S ++ S+D S S S + DS+
Sbjct: 615 DSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDS 674
Query: 301 QPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLDVTDTSM 360
SS+S SS+ + S S SS +S+ +D + S + D + +D+
Sbjct: 675 SDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS------NSSDSDS 728
Query: 361 DTYLEREWGNKPSDCVPYKDEELYDLPAPCTPLSLSCLQLSTPENRESSVVQAGGSKKHS 420
+ + SD D + + S S + ++ +SS + S +
Sbjct: 729 SNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS--DSSNSSDSN 786
Query: 421 NHLRKLVFDDFCDSSNVSNKDSSEDDISRSENEKKSECFSSPKTGFWDCCSTSYAQNLDF 480
+ D +SS+ SN S D S+++ + SS + D ++S + +
Sbjct: 787 DSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSD-SS 845
Query: 481 ESSEGNTIANSVGEISSKLSEKSGLC-LSKRLNSIRSFEMNRTRTSSEASMDAAYLDKIS 539
+SS+G+ +S SS S+ S S +S S + N + SS++S + D S
Sbjct: 846 DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDS 905
Query: 540 ELDSMMSESDNS--KSPCNNGFKSLDLDGLSKSSQGSEFLEEPDKLEEKTELNLSKGSLT 597
S S+S +S S + S D S SS S+ + D N S S +
Sbjct: 906 SDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNS 965
Query: 598 NDQLENGSEWKPTSFFLLSPSDQEMNEDFSLHSSS 632
+D ++ S S SD + D S S S
Sbjct: 966 SDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1000
Score = 64.7 bits (156), Expect = 3e-10
Identities = 122/594 (20%), Positives = 205/594 (34%), Gaps = 40/594 (6%)
Query: 129 DPLTLVQGNQNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKL 188
DP + + N N+D + +DN S + + N K +D D ++
Sbjct: 464 DPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNN 523
Query: 189 KLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSDKYIE 248
NG N D+ G+ K + + +++ + + SD
Sbjct: 524 SDSNGNGNNGN-------DDNDKSDSGK-------GKSDSSDSDSSDSSNSSDSSDSSDS 569
Query: 249 ELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARKQPGSSTSS 308
+ NSS + ++ +S + +D S S + S + DS+ S + S
Sbjct: 570 DSSDS-----NSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKS 624
Query: 309 SSHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLDVTDTSMDTYLEREW 368
S ++ SS S + ++S + N + D +D+S D+ +
Sbjct: 625 DSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSS-DSSSSSDS 683
Query: 369 GNKPSDCVPYKDEELYDLPAPCTPLSLS-CLQLSTPENRESSVVQAGGSKKHSNHLRKLV 427
N SD D + + S S S N SS + S S+
Sbjct: 684 SNS-SDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD 742
Query: 428 FDDFCDSSNVSNKDSSEDDISRSENEKKSECFSSPKTGFWDCCSTSYAQNLDFESSEGNT 487
D DSSN S+ S D + S++ S+ S + S S N SS+ +
Sbjct: 743 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDS------SNSSDSNDSSNSSDSSD 796
Query: 488 IANSVGEISSKLSEKSGLCLSKRLNSIRSFEMNRTRTSSEASMDAAYLDKISELDSMMSE 547
+NS SS S+ S S +S S + + + SS++S + D D S+
Sbjct: 797 SSNS--SDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSD 854
Query: 548 SDNSKSPCNNGFKSLDLDGLSKSSQGSEFLEEPDKLEEKTELNLSKGSLTNDQLENGSEW 607
S N N S D S SS S+ + D E + S S ++D + S
Sbjct: 855 SSNRSDSSN----SSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSN 910
Query: 608 KPTSFFLLSPSDQEMNEDFSLHSSSCPVTNEIKPPSCLFQTEFSQGILLSSSHRLFEDQR 667
S SD + D S S+S +N + ++ S S S +
Sbjct: 911 SSDS------SDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSN 964
Query: 668 FGSSLFKMSSEMHSLHNHLQSPWSTSFVPEKRNKNVNQSTKRKIQSSLSSASPS 721
S SS+ N S S+ + + + S+ S S +S S
Sbjct: 965 SSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNS 1018
Score = 57.8 bits (138), Expect = 4e-08
Identities = 83/384 (21%), Positives = 133/384 (34%), Gaps = 44/384 (11%)
Query: 259 NSSEEKEAMNSI----CQTALSADGKGSKGSEEDVVSKNQGDSARKQPGSSTSSSSHLAK 314
NSS+ ++ NS ++ S+D S S + S N D++ S++S SS +
Sbjct: 890 NSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSD 949
Query: 315 PSSSRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLDVTDTSMDTYLEREWGNKPSD 374
S+S SS S+ +D N S + D D +D+S SD
Sbjct: 950 SSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSS-----DSSDSS-----------DSSD 993
Query: 375 CVPYKDEELYDLPAPCTPLSLSCLQLSTPENRESSVVQAGGSKKHSNHLRKLVFDDFCDS 434
D S+ + S + S SN D DS
Sbjct: 994 SSDSSDSSN-----------------SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS 1036
Query: 435 SNVSNKDSSEDDISRSENEKKSECFSSPKTGFWDCCSTSYAQNLDFESSEGNTIANSVGE 494
S+ S+ S D S++ S+ S + S S + ESS+ + +NS
Sbjct: 1037 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDS 1096
Query: 495 ISSKLSEKSGLCLSKRLNSIRSFEMNRTRTSSEASMDAAYLDKISELDSMMSESDNSKSP 554
S S S +S S + + + SS +S + D DS S + S
Sbjct: 1097 SDSSDSSDSS-------DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSE 1149
Query: 555 CNNGFKSLDLDGLSKSSQGSEFLEEPDKLEEKTELNLSKGSLTNDQLENGSEWKPTSFFL 614
++ S D S SS S+ + D + S S ++D ++ +
Sbjct: 1150 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1209
Query: 615 LSPSDQEMNEDFSLHSSSCPVTNE 638
S S + S SS +NE
Sbjct: 1210 SSDSSDSSDSSDSSDSSDSSDSNE 1233
Score = 55.5 bits (132), Expect = 2e-07
Identities = 74/335 (22%), Positives = 133/335 (39%), Gaps = 10/335 (2%)
Query: 259 NSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARKQPGSSTSSSSHLAKPSSS 318
NSS+ ++ NS ++ S+D S S + S + DS+ S++S SS+ + S+S
Sbjct: 972 NSSDSSDSSNS-SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNS 1030
Query: 319 RLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLDVTDTSMDTYLEREWGNKPSDCVPY 378
SS +S+ +D + S + + + D +D+S + + SD
Sbjct: 1031 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS-DSSDSS-----DSSDSSDSSDSSES 1084
Query: 379 KDEELYDLPAPCTPLSLSCLQLSTPENRESSVVQAGGSKKHSNHLRKLVFDDFCDSSNVS 438
D + + S S + ++ +SS + S S+ D DSSN S
Sbjct: 1085 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS--DSSDSSNSSDSSDSSDSSDSSDSSNSS 1142
Query: 439 NK-DSSEDDISRSENEKKSECFSSPKTGFWDCCSTSYAQNLDFESSEGNTIANSVGEISS 497
+ DSSE S ++ SS + D +S + + S ++ +S SS
Sbjct: 1143 DSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1202
Query: 498 KLSEKSGLCLSKRLNSIRSFEMNRTRTSSEASMDAAYLDKISELDSMMSESDNSKSPCNN 557
S+ S S + + + S S D++ S+ + SD+S S +
Sbjct: 1203 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDST 1262
Query: 558 GFKSLDLDGLSKSSQGSEFLEEPDKLEEKTELNLS 592
+ + D SKS G+ + D E ++ N S
Sbjct: 1263 SDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHS 1297
Score = 42.7 bits (99), Expect = 0.001
Identities = 60/265 (22%), Positives = 100/265 (37%), Gaps = 12/265 (4%)
Query: 241 ERSDKYIEELESQVAQLKNSSEEKEAMNSI--CQTALSADGKGSKGSEEDVVSKNQGDSA 298
+ SD S + NSS+ ++ +S ++ S+D S S + S N DS+
Sbjct: 1038 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS 1097
Query: 299 RKQPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLDVTDT 358
S +S SS + S S SS +S+ +D + S N + E D +D+
Sbjct: 1098 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSE-SSDSSDS 1156
Query: 359 SMDTYLEREWGNKPSDCVPYKDEELYDLPAPCTPLSLSCLQLSTPENRESSVVQAGGSKK 418
S + + SD D + + S S + ++ +SS + S
Sbjct: 1157 S-----DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS--DSSDSSD 1209
Query: 419 HSNHLRKLVFDDFCDSSNVSNKDSSEDDISRSENEKKSECFSSPKTGFWDCCSTSYAQNL 478
S+ D DSS+ S+ + S D S++ S S + ++
Sbjct: 1210 SSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDES 1269
Query: 479 DFESSEGNTIANSVGEISSKLSEKS 503
D +S GN N+ G S SE S
Sbjct: 1270 DSQSKSGN--GNNNGSDSDSDSEGS 1292
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 55.5 bits (132), Expect = 2e-07
Identities = 76/346 (21%), Positives = 145/346 (41%), Gaps = 55/346 (15%)
Query: 89 KTRLELLHKEYEDEIDCLQKEVEELKSKNLSLE---SQIKTILDPLTLVQGNQNEDKHLV 145
K +LE KE + + ++ EL +K LE S++K +D L L ++KH
Sbjct: 916 KIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHAT 975
Query: 146 TDNPSKINPE------TVAEWKKKLRTANEIYEKVKDDV----DKLKEANK-KLKLEN-- 192
+ + E T+A+ K+ + E +++ DD+ DK+ K K+KLE
Sbjct: 976 ENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQV 1035
Query: 193 ----GGLVRE----------------NLRLKAE----VDNRSPQ-----KFGRFAVAALQ 223
G L +E +L+L E ++N Q K F ++ LQ
Sbjct: 1036 DDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQ 1095
Query: 224 SKVEQYERETNRLKKALERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALS------A 277
SK+E + +L+K ++ IEELE ++ + S + E S L
Sbjct: 1096 SKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLE 1155
Query: 278 DGKGSKGSEEDVVSKNQGDSARKQPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLN 337
+ G+ ++ ++ K + + + + ++ H A ++ R S + +L
Sbjct: 1156 EAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQ 1215
Query: 338 CSKNKDLYQEQVEVMLDVTD--TSMDTYLEREWGNKPSDCVPYKDE 381
K K L +E+ E+ +++ D ++M+T + + GN C +D+
Sbjct: 1216 RVKQK-LEKEKSEMKMEIDDLASNMET-VSKAKGNLEKMCRALEDQ 1259
Score = 42.4 bits (98), Expect = 0.002
Identities = 38/181 (20%), Positives = 82/181 (45%), Gaps = 10/181 (5%)
Query: 88 RKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLT--LVQGNQNEDKHLV 145
R LE K+ + ++ VE + +K SLE + + + + ++ +
Sbjct: 1386 RTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAA 1445
Query: 146 TDNPSKINPETVAEWKKK-------LRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRE 198
D + + +AEWK+K L + + + ++ K+K A ++ + L RE
Sbjct: 1446 LDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRE 1505
Query: 199 NLRLKAEVDNRSPQ-KFGRFAVAALQSKVEQYERETNRLKKALERSDKYIEELESQVAQL 257
N L+ E+ + + Q G + L+ +Q E+E + L+ ALE ++ +E E ++ ++
Sbjct: 1506 NKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRI 1565
Query: 258 K 258
+
Sbjct: 1566 Q 1566
Score = 41.6 bits (96), Expect = 0.003
Identities = 62/295 (21%), Positives = 121/295 (41%), Gaps = 48/295 (16%)
Query: 89 KTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTDN 148
K +LE E + EID L +E + +LE + + D L+ ++ + E + L+ D
Sbjct: 1218 KQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLIND- 1276
Query: 149 PSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRLKAEVDN 208
+ + +L+T + Y + D+ D L +L ++ LK +++
Sbjct: 1277 --------LTAQRARLQTESGEYSRQLDEKDTLV---SQLSRGKQAFTQQIEELKRQLEE 1325
Query: 209 RSPQKFGRFAVAALQSK-------VEQYERETN---RLKKALERSD--------KY---- 246
K ALQS EQYE E L++A+ +++ KY
Sbjct: 1326 EIKAKSA--LAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDA 1383
Query: 247 ------IEELESQVAQ-LKNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSAR 299
+EE + ++AQ L+++ E EA+N+ C +L + + ED++ + +A
Sbjct: 1384 IQRTEELEEAKKKLAQRLQDAEEHVEAVNAKC-ASLEKTKQRLQNEVEDLMIDVERTNAA 1442
Query: 300 KQPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLNCS----KNKDLYQEQVE 350
+ + C+ + A E++ K + S K K+ Y+E ++
Sbjct: 1443 CAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLD 1497
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 54.7 bits (130), Expect = 3e-07
Identities = 74/345 (21%), Positives = 141/345 (40%), Gaps = 53/345 (15%)
Query: 89 KTRLELLHKEYEDEIDCLQKEVEELKSKNLSLE---SQIKTILDPLTLVQGNQNEDKHLV 145
K +LE KE + + ++ EL +K LE S++K +D L L ++KH
Sbjct: 918 KIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHAT 977
Query: 146 TDNPSKINPE------TVAEWKKKLRTANEIYEKVKDDV----DKLKEANK-KLKLEN-- 192
+ + E T+A+ K+ + E +++ DD+ DK+ K K+KLE
Sbjct: 978 ENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQV 1037
Query: 193 ----GGLVREN-LRLKAE-------------------VDNRSPQ-----KFGRFAVAALQ 223
G L +E LR+ E ++N Q K F ++ LQ
Sbjct: 1038 DDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQ 1097
Query: 224 SKVEQYERETNRLKKALERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALS------A 277
SK+E + +L+K ++ IEELE ++ + S + E S L
Sbjct: 1098 SKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLE 1157
Query: 278 DGKGSKGSEEDVVSKNQGDSARKQPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLN 337
+ G+ ++ ++ K + + + + ++ H A ++ R S + +L
Sbjct: 1158 EAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQ 1217
Query: 338 CSKNKDLYQEQVEVMLDVTDTSMDT-YLEREWGNKPSDCVPYKDE 381
K K L +E+ E+ +++ D + + + + GN C +D+
Sbjct: 1218 RVKQK-LEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261
Score = 42.0 bits (97), Expect = 0.002
Identities = 54/299 (18%), Positives = 125/299 (41%), Gaps = 44/299 (14%)
Query: 89 KTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTD- 147
K +LE E + EID L VE + +LE +T+ D L+ ++ + E + L+ D
Sbjct: 1220 KQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDL 1279
Query: 148 --NPSKINPETVAEWKKKLRTANEIYEKVK-------DDVDKLK-EANKKLKLENG---- 193
++ E+ E+ ++L + ++ +++LK + +++K +N
Sbjct: 1280 TAQRGRLQTES-GEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHA 1338
Query: 194 --------GLVRENL-----------RLKAEVDNRSPQKFGRFAVAALQSKVEQYERETN 234
L+RE R ++ + Q ++ A+Q + E+ E
Sbjct: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQ-RTEELEEAKK 1397
Query: 235 RLKKALERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKN- 293
+L + L+ +++++E + ++ A L+ + + + N + L + + + D +N
Sbjct: 1398 KLAQRLQAAEEHVEAVNAKCASLEKTKQRLQ--NEVEDLMLDVERTNAACAALDKKQRNF 1455
Query: 294 -----QGDSARKQPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQE 347
+ ++ + +S A+ + L +A +ES + + +NK+L QE
Sbjct: 1456 DKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQE 1514
Score = 34.3 bits (77), Expect = 0.42
Identities = 37/194 (19%), Positives = 73/194 (37%), Gaps = 36/194 (18%)
Query: 88 RKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLT--LVQGNQNEDKHLV 145
R LE K+ + ++ VE + +K SLE + + + + ++ +
Sbjct: 1388 RTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAA 1447
Query: 146 TDNPSKINPETVAEWKKKLRTAN---------------------EIYEKVKDDVDKLKEA 184
D + + +AEWK+K + YE+ D ++ LK
Sbjct: 1448 LDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRE 1507
Query: 185 NKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSD 244
NK L+ E L + G + L+ +Q E+E L+ ALE ++
Sbjct: 1508 NKNLQQEISDLTEQIAE-------------GGKRIHELEKIKKQVEQEKCELQAALEEAE 1554
Query: 245 KYIEELESQVAQLK 258
+E E ++ +++
Sbjct: 1555 ASLEHEEGKILRIQ 1568
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 54.7 bits (130), Expect = 3e-07
Identities = 74/345 (21%), Positives = 141/345 (40%), Gaps = 53/345 (15%)
Query: 89 KTRLELLHKEYEDEIDCLQKEVEELKSKNLSLE---SQIKTILDPLTLVQGNQNEDKHLV 145
K +LE KE + + ++ EL +K LE S++K +D L L ++KH
Sbjct: 918 KIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHAT 977
Query: 146 TDNPSKINPE------TVAEWKKKLRTANEIYEKVKDDV----DKLKEANK-KLKLEN-- 192
+ + E T+A+ K+ + E +++ DD+ DK+ K K+KLE
Sbjct: 978 ENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQV 1037
Query: 193 ----GGLVREN-LRLKAE-------------------VDNRSPQ-----KFGRFAVAALQ 223
G L +E LR+ E ++N Q K F ++ LQ
Sbjct: 1038 DDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQ 1097
Query: 224 SKVEQYERETNRLKKALERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALS------A 277
SK+E + +L+K ++ IEELE ++ + S + E S L
Sbjct: 1098 SKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLE 1157
Query: 278 DGKGSKGSEEDVVSKNQGDSARKQPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLN 337
+ G+ ++ ++ K + + + + ++ H A ++ R S + +L
Sbjct: 1158 EAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQ 1217
Query: 338 CSKNKDLYQEQVEVMLDVTDTSMDT-YLEREWGNKPSDCVPYKDE 381
K K L +E+ E+ +++ D + + + + GN C +D+
Sbjct: 1218 RVKQK-LEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261
Score = 42.0 bits (97), Expect = 0.002
Identities = 54/299 (18%), Positives = 125/299 (41%), Gaps = 44/299 (14%)
Query: 89 KTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTD- 147
K +LE E + EID L VE + +LE +T+ D L+ ++ + E + L+ D
Sbjct: 1220 KQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDL 1279
Query: 148 --NPSKINPETVAEWKKKLRTANEIYEKVK-------DDVDKLK-EANKKLKLENG---- 193
++ E+ E+ ++L + ++ +++LK + +++K +N
Sbjct: 1280 TAQRGRLQTES-GEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHA 1338
Query: 194 --------GLVRENL-----------RLKAEVDNRSPQKFGRFAVAALQSKVEQYERETN 234
L+RE R ++ + Q ++ A+Q + E+ E
Sbjct: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQ-RTEELEEAKK 1397
Query: 235 RLKKALERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKN- 293
+L + L+ +++++E + ++ A L+ + + + N + L + + + D +N
Sbjct: 1398 KLAQRLQAAEEHVEAVNAKCASLEKTKQRLQ--NEVEDLMLDVERTNAACAALDKKQRNF 1455
Query: 294 -----QGDSARKQPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQE 347
+ ++ + +S A+ + L +A +ES + + +NK+L QE
Sbjct: 1456 DKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQE 1514
Score = 34.3 bits (77), Expect = 0.42
Identities = 37/194 (19%), Positives = 73/194 (37%), Gaps = 36/194 (18%)
Query: 88 RKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLT--LVQGNQNEDKHLV 145
R LE K+ + ++ VE + +K SLE + + + + ++ +
Sbjct: 1388 RTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAA 1447
Query: 146 TDNPSKINPETVAEWKKKLRTAN---------------------EIYEKVKDDVDKLKEA 184
D + + +AEWK+K + YE+ D ++ LK
Sbjct: 1448 LDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRE 1507
Query: 185 NKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSD 244
NK L+ E L + G + L+ +Q E+E L+ ALE ++
Sbjct: 1508 NKNLQQEISDLTEQIAE-------------GGKRIHELEKIKKQVEQEKCELQAALEEAE 1554
Query: 245 KYIEELESQVAQLK 258
+E E ++ +++
Sbjct: 1555 ASLEHEEGKILRIQ 1568
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 52.8 bits (125), Expect = 1e-06
Identities = 68/299 (22%), Positives = 131/299 (43%), Gaps = 32/299 (10%)
Query: 74 ESEPMLSHTVRKHLRKTRLEL---------LHKEYEDEIDCLQKEVEELKSKNLSLESQI 124
E+E HT+ ++L L+ LH ++ + QKE+ LK ++E Q+
Sbjct: 856 ENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQV 915
Query: 125 KTILDPLTLVQGNQNEDKHLVTDNPSKINP--ETVAEWKKKLRTANEIYEKVKDDVDKLK 182
+ T Q +K V D S++ E V + K++L+T+ E+ + V L+
Sbjct: 916 ASQSSQRT--GKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLE 973
Query: 183 EANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALER 242
E+ K K V E +R EV + +F L+ K+ + E+E L+ R
Sbjct: 974 ESLNKEKQ-----VTEEVRKNIEVRLKESAEFQ----TQLEKKLMEVEKEKQELQDDKRR 1024
Query: 243 SDKYIEELESQVAQLKN--SSEEKEAMNSI--CQTALSADGKGSKGSEEDVVSKNQGDSA 298
+ IE +E Q+++LK SS + E ++ TALS + + + +E + +
Sbjct: 1025 A---IESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNK 1081
Query: 299 RKQP---GSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLD 354
++ ++ + AK S++ +E+T KA+ + K ++E+ ++ D
Sbjct: 1082 YERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKD 1140
Score = 42.4 bits (98), Expect = 0.002
Identities = 41/177 (23%), Positives = 77/177 (43%), Gaps = 18/177 (10%)
Query: 97 KEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTDNPSKINPET 156
K ++++ LQ++V +L+S+N + +Q+ ++Q N + +T + T
Sbjct: 691 KIQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLT 750
Query: 157 VAEWKKK---------LRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRLKAEVD 207
K++ LR ANE + + LK+ + LKL L ++ L AE
Sbjct: 751 ATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAE-- 808
Query: 208 NRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSDKYIEELESQVAQLKNSSEEK 264
+ Q + +Q +E+ E ET +R IE+LE +++ LK E +
Sbjct: 809 -QRGQNLLLTNLQTIQGILERSETETK------QRLSSQIEKLEHEISHLKKKLENE 858
Score = 40.4 bits (93), Expect = 0.006
Identities = 69/342 (20%), Positives = 136/342 (39%), Gaps = 48/342 (14%)
Query: 87 LRKTRLELLHKE--YEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHL 144
L++ EL K + E L+++V+ K++N L SQ K DP T +K +
Sbjct: 1307 LQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQK---DPDTEEYRKLLSEKEV 1363
Query: 145 VTDNPSKINPET------VAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRE 198
T ++ E +A L + + +K+D++K++ + ++ + + +
Sbjct: 1364 HTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIID 1423
Query: 199 --------------NLRLKAEVDNRSPQKFGRFAVAALQSKVEQYE----RETNRLKKAL 240
R K + + Q+ +A S Q + +E LK+ L
Sbjct: 1424 IQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETL 1483
Query: 241 ERSDKYIEELESQVAQLKN--SSEEKEAMNSICQTA--------LSADGKGSKGSEEDVV 290
+++ + LESQV L+ S +E EA N QT L D + EE +
Sbjct: 1484 NQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLR 1543
Query: 291 SK--NQGDSARKQPGSSTSSSSHLA------KPSSSRLCDTSSARQESTSKADLNCSKNK 342
+ + + RK ++ S +HLA + L + A + + D+ + K
Sbjct: 1544 QQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALK 1603
Query: 343 DLYQEQVEVMLDVTDTSMDTYLE-REWGNKPSDCVPYKDEEL 383
Y+ ++ + + +LE R+ +PS+ VP + ++
Sbjct: 1604 SQYEGRISRLERELREHQERHLEQRDEPQEPSNKVPEQQRQI 1645
Score = 38.9 bits (89), Expect = 0.017
Identities = 39/158 (24%), Positives = 75/158 (47%), Gaps = 8/158 (5%)
Query: 98 EYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQ--GNQNEDKHLVTDNPSKINPE 155
E E D ++KE+ E + LE +++ D L+ + G ++ L +P+
Sbjct: 330 EVEQSKDQMEKEMLEKIGR---LEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVA 386
Query: 156 TVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFG 215
+ + KL Y + +D + K NK++ +V+E + KA + R +++
Sbjct: 387 KIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKE-VEAKAPILKRQREEYE 445
Query: 216 RF--AVAALQSKVEQYERETNRLKKALERSDKYIEELE 251
R AVA+L K+EQ +E RL++ ++++K LE
Sbjct: 446 RAQKAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLE 483
Score = 35.0 bits (79), Expect = 0.25
Identities = 65/284 (22%), Positives = 105/284 (36%), Gaps = 44/284 (15%)
Query: 80 SHTVRKHLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQI---KTILDPLTLVQG 136
S T K +++E L E L+ EVE+ + +L+ Q+ K LD T +
Sbjct: 829 SETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHL 888
Query: 137 N-----QNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLE 191
N +N K + T N E + RT K+DVD L ++ + +
Sbjct: 889 NTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKG-QPSNKEDVDDLVSQLRQTEEQ 947
Query: 192 NGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSDKYIEELE 251
L RLK N VEQY+ L+++L + + EE+
Sbjct: 948 VNDLKE---RLKTSTSN-----------------VEQYQAMVTSLEESLNKEKQVTEEVR 987
Query: 252 SQV-AQLKNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARKQPGSSTSSSS 310
+ +LK S+E QT L K E + + D R+ S S
Sbjct: 988 KNIEVRLKESAE--------FQTQLE-----KKLMEVEKEKQELQDDKRRAIESMEQQLS 1034
Query: 311 HLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLD 354
L K SS + A Q +++ +D QEQ ++ ++
Sbjct: 1035 ELKKTLSSVQNEVQEALQRASTALSNEQQARRDC-QEQAKIAVE 1077
Score = 35.0 bits (79), Expect = 0.25
Identities = 42/191 (21%), Positives = 80/191 (41%), Gaps = 13/191 (6%)
Query: 94 LLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTDNPSKIN 153
+LH + + +++V ++ S LE + L + + E + ++ D SK
Sbjct: 1087 MLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCV 1146
Query: 154 PETVAEWKKKLRTANEIYEKVKDDV-DKLKEA-----NKKLKLENGGLVRENLRLKAEVD 207
+ +K+ R ++ EK+ D V +KE N L E G + L + +
Sbjct: 1147 CRC-EDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLS-EEGKSQEQILEILRFIR 1204
Query: 208 NRSPQKFGRFAVAALQS-----KVEQYERETNRLKKALERSDKYIEELESQVAQLKNSSE 262
RF VA ++S +VE ERE L+ +L + ++ +AQ + +
Sbjct: 1205 REKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMK 1264
Query: 263 EKEAMNSICQT 273
+ E MN + +T
Sbjct: 1265 KTETMNVVMET 1275
Score = 33.9 bits (76), Expect = 0.55
Identities = 52/267 (19%), Positives = 105/267 (39%), Gaps = 60/267 (22%)
Query: 74 ESEPMLSHTVRKHLRKTR----LELLHKEYEDEIDCL---QKEVEELKSKNLSLESQIKT 126
E E LSH+ + + +TR L L ++ +++ L KE+E + +N++++SQ
Sbjct: 56 EIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQF-- 113
Query: 127 ILDPLTLVQGNQNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANK 186
++ E AE + +RT + ++++ + +K N+
Sbjct: 114 -----------------------TRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNE 150
Query: 187 KLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSDKY 246
KLK N + L+LK + + A V+ E+ + K+ L + +
Sbjct: 151 KLKESN--TTKGELQLKLD------------ELQASDVSVKYREKRLEQEKELLHSQNTW 196
Query: 247 IE-ELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARKQPGSS 305
+ EL+++ +L EK N I + + + K K + +Q
Sbjct: 197 LNTELKTKTDELLALGREKG--NEILELKCNLENK-----------KEEVSRLEEQMNGL 243
Query: 306 TSSSSHLAKPSSSRLCDTSSARQESTS 332
+S+ HL K L A+++ S
Sbjct: 244 KTSNEHLQKHVEDLLTKLKEAKEQQAS 270
>gi|38570058 hypothetical protein LOC80129 [Homo sapiens]
Length = 715
Score = 52.4 bits (124), Expect = 1e-06
Identities = 63/304 (20%), Positives = 122/304 (40%), Gaps = 46/304 (15%)
Query: 102 EIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVT---DNPSKINPETVA 158
+ +C Q E+++L+SK LS E + + + + N L+T D ++ E+ A
Sbjct: 55 KFECAQSELQDLRSKMLSKEVSCQELKAEMESYKENNARKSSLLTSLRDRVQELEEESAA 114
Query: 159 EWKKKLRTANEIYEKVKDDVD---KLKEANKKLKL------ENGGLVRENLRLKAEV--- 206
K+RT + +K++ + K+ E N+KL+ EN V +N R E
Sbjct: 115 LSTSKIRTEITAHAAIKENQELKKKVVELNEKLQKCSKENEENKKQVSKNCRKHEEFLTQ 174
Query: 207 ------------------------DNRSPQKFGRFAVAALQSKVEQYERETNRLKKALER 242
D R +F + + L+ + +E E ++ + R
Sbjct: 175 LRDCLDPDERNDKASDEDLILKLRDLRKENEFVKGQIVILEETINVHEMEAKASRETIMR 234
Query: 243 SDKYIEELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARKQP 302
E+ + + + +EEKE +N +A+ A + E +V + A +Q
Sbjct: 235 ---LASEVNREQKKAASCTEEKEKLNQDLLSAVEA----KEALEREVKIFQERLLAGQQV 287
Query: 303 GSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLDVTDTSMDT 362
++ L K SSS L + A Q++ + + ++ + L +T ++ DT
Sbjct: 288 WDASKQEVSLLKKSSSELEKSLKASQDAVTTSQSQYFSFREKIAALLRGRLSMTGSTEDT 347
Query: 363 YLER 366
LE+
Sbjct: 348 ILEK 351
>gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens]
Length = 699
Score = 51.6 bits (122), Expect = 3e-06
Identities = 108/497 (21%), Positives = 188/497 (37%), Gaps = 98/497 (19%)
Query: 3 QTVQNVTLSLTLPITCHICLGKVRQPVICINNHVFCSICIDLWL---KNNSQCPACRVPI 59
+ VQNV ++ + C ICL +++PV +H+FC C+ L K SQCP C+ I
Sbjct: 9 EEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDI 68
Query: 60 TPENPCKEIIGGTSESEPMLSHTVRKHLRKTRLELLHKEYEDEIDCLQKE--VEELKSKN 117
T R TR L +E I Q + +E S N
Sbjct: 69 TK----------------------RSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYN 106
Query: 118 LSLE--SQIKTILDPLTLVQ--GNQNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEK 173
+ + + + + D ++++Q G +N K L+ P NP
Sbjct: 107 FAKKENNSPEHLKDEVSIIQSMGYRNRAKRLLQSEPE--NP------------------- 145
Query: 174 VKDDVDKLKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERET 233
L+E + ++L N G VR LR K + PQK + S + + T
Sbjct: 146 ------SLQETSLSVQLSNLGTVR-TLRTKQRI---QPQKTSVYIELGSDSSEDTVNKAT 195
Query: 234 NRLKKALERSDKYIEELESQVAQL-KNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSK 292
Y + ++ Q+ + ++ +++S + A +E S
Sbjct: 196 ------------YCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQPSN 243
Query: 293 NQGDSARKQPGSSTSSSSHLAKPSSSRLCDTSSARQES--TSKADLNCSKNKDLYQEQVE 350
N ++ K+ + + + +S +TS + S +S++D+ ++ +D Q +
Sbjct: 244 NDLNTTEKR-AAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNL- 301
Query: 351 VMLDVTDTSMDTYLEREWGNKPSDCVP---YKDEELYDLPAPCTPLSLSCLQLSTPENRE 407
+ L ++ LE+ G++PS+ P L DL P + ST E
Sbjct: 302 IKLQQEMAELEAVLEQH-GSQPSNSYPSIISDSSALEDLRNP---------EQSTSEKVL 351
Query: 408 SSVVQAGGSKKHSNHLRKLVFDDFCDSSNVSNKDSSEDDISRSENEKKSECFSSPKTGFW 467
+S Q S + L D F S++ S + E + RS S+C S +
Sbjct: 352 TS--QKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERS---SPSKCPSLDDRWYM 406
Query: 468 DCCSTSYAQNLDFESSE 484
CS S QN ++ S E
Sbjct: 407 HSCSGS-LQNRNYPSQE 422
>gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens]
Length = 759
Score = 51.6 bits (122), Expect = 3e-06
Identities = 108/497 (21%), Positives = 188/497 (37%), Gaps = 98/497 (19%)
Query: 3 QTVQNVTLSLTLPITCHICLGKVRQPVICINNHVFCSICIDLWL---KNNSQCPACRVPI 59
+ VQNV ++ + C ICL +++PV +H+FC C+ L K SQCP C+ I
Sbjct: 9 EEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDI 68
Query: 60 TPENPCKEIIGGTSESEPMLSHTVRKHLRKTRLELLHKEYEDEIDCLQKE--VEELKSKN 117
T R TR L +E I Q + +E S N
Sbjct: 69 TK----------------------RSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYN 106
Query: 118 LSLE--SQIKTILDPLTLVQ--GNQNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEK 173
+ + + + + D ++++Q G +N K L+ P NP
Sbjct: 107 FAKKENNSPEHLKDEVSIIQSMGYRNRAKRLLQSEPE--NP------------------- 145
Query: 174 VKDDVDKLKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERET 233
L+E + ++L N G VR LR K + PQK + S + + T
Sbjct: 146 ------SLQETSLSVQLSNLGTVR-TLRTKQRI---QPQKTSVYIELGSDSSEDTVNKAT 195
Query: 234 NRLKKALERSDKYIEELESQVAQL-KNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSK 292
Y + ++ Q+ + ++ +++S + A +E S
Sbjct: 196 ------------YCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQPSN 243
Query: 293 NQGDSARKQPGSSTSSSSHLAKPSSSRLCDTSSARQES--TSKADLNCSKNKDLYQEQVE 350
N ++ K+ + + + +S +TS + S +S++D+ ++ +D Q +
Sbjct: 244 NDLNTTEKR-AAERHPEKYQGEAASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNL- 301
Query: 351 VMLDVTDTSMDTYLEREWGNKPSDCVP---YKDEELYDLPAPCTPLSLSCLQLSTPENRE 407
+ L ++ LE+ G++PS+ P L DL P + ST E
Sbjct: 302 IKLQQEMAELEAVLEQH-GSQPSNSYPSIISDSSALEDLRNP---------EQSTSEKVL 351
Query: 408 SSVVQAGGSKKHSNHLRKLVFDDFCDSSNVSNKDSSEDDISRSENEKKSECFSSPKTGFW 467
+S Q S + L D F S++ S + E + RS S+C S +
Sbjct: 352 TS--QKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERS---SPSKCPSLDDRWYM 406
Query: 468 DCCSTSYAQNLDFESSE 484
CS S QN ++ S E
Sbjct: 407 HSCSGS-LQNRNYPSQE 422
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 50.8 bits (120), Expect = 4e-06
Identities = 113/557 (20%), Positives = 219/557 (39%), Gaps = 83/557 (14%)
Query: 162 KKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAA 221
++L E KV+ ++++++ +++L LE ++ E L+ + E+ + + R A
Sbjct: 859 EELLKVKEKQTKVEGELEEMERKHQQL-LEEKNILAEQLQAETELFAEAEEMRARLAAKK 917
Query: 222 ---------LQSKVEQYERETNRLKKALERSDKYIEELESQVAQLKNSSEEKEAMNSICQ 272
L+S+VE+ E L+ ++ +I++LE Q+ EE+ A +
Sbjct: 918 QELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQL------DEEEGARQKLQL 971
Query: 273 TALSADGKGSKGSEEDVVSKNQGDSARKQPGSSTSSSSHLAKPSSSRLCDTSSARQESTS 332
++A+ K K EE ++ ++Q K+ K R+ + SS E
Sbjct: 972 EKVTAEAKIKKMEEEILLLEDQNSKFIKE-----------KKLMEDRIAECSSQLAEEEE 1020
Query: 333 KADLNCSKNKDLYQEQVEVMLDVTDTSMDTYLEREWGNKPSDCVPYKDEELYDLPAPCTP 392
KA KN + + EVM ++D E + + D E DL
Sbjct: 1021 KA-----KNLAKIRNKQEVM--ISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAE 1073
Query: 393 LSLSC----LQLSTPENRESSVVQAGGSKK-HSNHLRKLVFDDFCDSSNVSNKDSSEDDI 447
L LQL+ E + G + H N+ K+V + + + +D +
Sbjct: 1074 LQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAEL-QEDFESEKA 1132
Query: 448 SRSENEKK----SECFSSPKTGFWDCCSTSYAQN----------LDFESSEGNTIANSVG 493
SR++ EK+ SE + KT D T+ AQ + + + N
Sbjct: 1133 SRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEA 1192
Query: 494 EISSKLSEKSGLC--LSKRLNSIRSFEMNRTRTSSEASMDAAYLD-KISELDSMMSESDN 550
+I + LS++L + F+ N + D L ++ L + +ES++
Sbjct: 1193 QIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEH 1252
Query: 551 SKSPCNNGFKSLDLDGLSKSSQGSEFLEEPDKLEEKTELNLSKGSLTNDQLENGSEWKPT 610
+ + + L +K S+G D+L + EL K S ++L+N S
Sbjct: 1253 KRKKLDAQVQELH----AKVSEG-------DRL--RVEL-AEKASKLQNELDNVST---- 1294
Query: 611 SFFLLSPSDQEMNEDFSLHSSSCPVTNEIKPPSCLFQTEFSQGILLSSSHRLFEDQRFGS 670
LL +++ + + + ++++ L Q E Q + LSS R E+++ +
Sbjct: 1295 ---LLEEAEK---KGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEK--N 1346
Query: 671 SLFKMSSEMHSLHNHLQ 687
SL + E +L+
Sbjct: 1347 SLQEQQEEEEEARKNLE 1363
Score = 42.0 bits (97), Expect = 0.002
Identities = 50/195 (25%), Positives = 90/195 (46%), Gaps = 28/195 (14%)
Query: 88 RKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTD 147
+K L ++ E+E + LQ++ EE + +LE Q+ + L + K V D
Sbjct: 1330 QKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLA-------DTKKKVDD 1382
Query: 148 NPSKINPETVAEWKKKL-RTANEIYEKVKDDV---DKLKEANKKLKLENGGLV--RENLR 201
+ I E++ E KKKL + A + +++++ DKL++ +L+ E L ++ R
Sbjct: 1383 DLGTI--ESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQR 1440
Query: 202 LKAEVDNRSPQKF-----------GRFAVAALQSKVEQYERETNRLK--KALERSDKYIE 248
A + +KF R+A +++ E E+ET L +ALE + + E
Sbjct: 1441 QVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKE 1500
Query: 249 ELESQVAQLKNSSEE 263
E E Q QL+ E+
Sbjct: 1501 EFERQNKQLRADMED 1515
Score = 36.2 bits (82), Expect = 0.11
Identities = 47/210 (22%), Positives = 85/210 (40%), Gaps = 42/210 (20%)
Query: 66 KEIIGGTSESEPMLSHTVRKHLRKTRLELLHK--EYEDEIDCLQKEVEELKSKNLSLESQ 123
+E++ E R+ L K + +L + + +D+I LQ +++ELK + E +
Sbjct: 1032 QEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEE 1091
Query: 124 IKTILDPLTLVQGNQNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKE 183
++ L + +D+ L +N K+ E A+ ++++D + K
Sbjct: 1092 LQGAL--------ARGDDETLHKNNALKVVRELQAQ-----------IAELQEDFESEKA 1132
Query: 184 ANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERS 243
+ K + + L E LK E+++ AA Q + E+E LKKALE
Sbjct: 1133 SRNKAEKQKRDLSEELEALKTELEDTLD------TTAAQQELRTKREQEVAELKKALEEE 1186
Query: 244 DK---------------YIEELESQVAQLK 258
K +EEL Q+ Q K
Sbjct: 1187 TKNHEAQIQDMRQRHATALEELSEQLEQAK 1216
Score = 35.8 bits (81), Expect = 0.14
Identities = 43/202 (21%), Positives = 86/202 (42%), Gaps = 15/202 (7%)
Query: 89 KTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTDN 148
K ++E+ K+ E +I+ K +E+ + L++Q+K L + +++E ++
Sbjct: 1619 KKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKES 1678
Query: 149 PSKINP---------ETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVREN 199
K+ E +A ++ R A + +++ D++ L E L
Sbjct: 1679 EKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARI 1738
Query: 200 LRLKAEVDNRSPQKF---GRFAVAALQSKVEQYERETNRLKKALERSDKYIEELESQVAQ 256
+L+ E++ RF LQ V+ E + A ++SD ++LE Q +
Sbjct: 1739 AQLEEELEEEQSNMELLNDRFRKTTLQ--VDTLNAELAAERSAAQKSDNARQQLERQNKE 1796
Query: 257 LKNSSEEKE-AMNSICQTALSA 277
LK +E E A+ S + +SA
Sbjct: 1797 LKAKLQELEGAVKSKFKATISA 1818
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 50.4 bits (119), Expect = 6e-06
Identities = 100/453 (22%), Positives = 182/453 (40%), Gaps = 93/453 (20%)
Query: 74 ESEPMLSHTVRKHLRKTRLELLHKEYEDEIDCLQ-------KEVEELKSKNLSLESQIKT 126
E + L+ +++ ++ R E ++ + + LQ ++E+ K+++L+L Q K+
Sbjct: 676 EKKERLTEELKEQMKAKRKEAELRQVQSQAHGLQMRLKYSQSDLEQTKTRHLALNLQEKS 735
Query: 127 IL------------DPLTLVQGNQNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKV 174
L D ++Q + E K L + +++ E E+ +++ N I E
Sbjct: 736 KLESELANFGPRINDIKRIIQSREREMKDL-KEKMNQVEDEVFEEFCREIGVRN-IREFE 793
Query: 175 KDDVDKLKE-ANKKLKLENGGLVRENLRLKAEVDNRSPQ-KFGRFAVAALQSKVEQYERE 232
++ V + E A K+L+ EN + RL ++D Q K + V + V++ E E
Sbjct: 794 EEKVKRQNEIAKKRLEFEN-----QKTRLGIQLDFEKNQLKEDQDKVHMWEQTVKKDENE 848
Query: 233 TNRLKKALERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSK 292
+LKK +R K I+E +Q+ LKN K++ +V K
Sbjct: 849 IEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKS---------------------EVNDK 887
Query: 293 N-QGDSARKQPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQEQVEV 351
N + + RK+ G + +HL K ++ +T ++ S L K +D +
Sbjct: 888 NHEMEEIRKKLGGANKEMTHLQKEVTA--IETKLEQKRSDRHNLLQACKMQD-------I 938
Query: 352 MLDVTDTSMDTYLEREWGNKPSDCV------------------PYKD--EELYDLPAPCT 391
L ++ +MD + E ++ D V Y D E+L D A
Sbjct: 939 KLPLSKGTMDDISQEEGSSQGEDSVSGSQRISSIYAREALIEIDYGDLCEDLKDAQAE-E 997
Query: 392 PLSLSCLQLSTPENRESSVVQ--AGGSKKHSNHLRKLVFDDFCDSSNVSNKDSSEDDISR 449
+ L N + SV+Q A + K L V D F ++S+ E + +R
Sbjct: 998 EIKQEMNTLQQKLNEQQSVLQRIAAPNMKAMEKLES-VRDKFQETSD-------EFEAAR 1049
Query: 450 SENEKKSECFSSPKTGFWD---CCSTSYAQNLD 479
+K + F K +D C S A N+D
Sbjct: 1050 KRAKKAKQAFEQIKKERFDRFNACFESVATNID 1082
Score = 40.0 bits (92), Expect = 0.008
Identities = 48/203 (23%), Positives = 86/203 (42%), Gaps = 42/203 (20%)
Query: 100 EDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTDNPSKINPETVAE 159
EDE+ +KE+ ++ + +E +IK L NQ +++ + + +
Sbjct: 260 EDELKEKKKELGKMMREQQQIEKEIKEKDSEL-----NQKRPQYIKAKENTSHKIKKLEA 314
Query: 160 WKKKLRTANEIYEKVKDDVDKLKE----------------------ANKKLKLENGGLVR 197
KK L+ A + Y+K K D+D+L++ + L LE V+
Sbjct: 315 AKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEE-NQVK 373
Query: 198 ENLRLKAEVDNRSP------QKFGRFAVA-------ALQSKVEQYERETNRLKKALERSD 244
+ RLK E R+ +KF R A + KVE + +L++ +E +
Sbjct: 374 KYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKLRE-IEENQ 432
Query: 245 KYIEELESQVAQLKNSSEEKEAM 267
K IE+LE + K S EE++ +
Sbjct: 433 KRIEKLEEYITTSKQSLEEQKKL 455
Score = 39.3 bits (90), Expect = 0.013
Identities = 29/117 (24%), Positives = 57/117 (48%), Gaps = 14/117 (11%)
Query: 153 NPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRLKAEVDNRSPQ 212
N + + K+L + N+ EK K +DK+++ K+ K E G ++RE +++ E+ + +
Sbjct: 231 NEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSE 290
Query: 213 KFGRFAVAALQSKVEQY----ERETNRLKKALERSDKYIEELESQVAQLKNSSEEKE 265
L K QY E ++++KK LE + K ++ + + K +E E
Sbjct: 291 ---------LNQKRPQYIKAKENTSHKIKK-LEAAKKSLQNAQKHYKKRKGDMDELE 337
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 50.1 bits (118), Expect = 7e-06
Identities = 72/327 (22%), Positives = 133/327 (40%), Gaps = 54/327 (16%)
Query: 89 KTRLELLHKEYEDEIDCLQKEVEELKSKNLSLE---SQIKTILDPLTLVQGNQNEDKHLV 145
K +LE KE + + ++ EL +K LE S++K +D L L ++KH
Sbjct: 916 KIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHAT 975
Query: 146 TDNPSKINPE------TVAEWKKKLRTANEIYEKVKDDV----DKLKEANK-KLKLEN-- 192
+ + E T+A+ K+ + E +++ DD+ DK+ K K KLE
Sbjct: 976 ENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQV 1035
Query: 193 ----GGLVRE----------------NLRLKAE----VDNRSPQ-----KFGRFAVAALQ 223
G L +E +L+L E +N Q K F ++ LQ
Sbjct: 1036 DDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQ 1095
Query: 224 SKVEQYERETNRLKKALERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALS------A 277
K+E + +L+K ++ IEELE ++ + S + E S L
Sbjct: 1096 GKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLE 1155
Query: 278 DGKGSKGSEEDVVSKNQGDSARKQPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLN 337
+ G+ ++ ++ K + + + + S+ H A ++ R S + L
Sbjct: 1156 EAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQ 1215
Query: 338 CSKNKDLYQEQVEVMLDVTD--TSMDT 362
K K L +E+ E+ +++ D ++M+T
Sbjct: 1216 RVKQK-LEKEKSELKMEINDLASNMET 1241
Score = 37.7 bits (86), Expect = 0.038
Identities = 55/248 (22%), Positives = 102/248 (41%), Gaps = 47/248 (18%)
Query: 88 RKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLT--LVQGNQNEDKHLV 145
R LE K+ + ++ VE + SK SLE + + + + ++ ++ +
Sbjct: 1386 RTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIA 1445
Query: 146 TDNPSKINPETVAEWKKK---------------------LRTANEIYEKVKDDVDKLKEA 184
D + + +AEWK+K L YE+ D ++ LK
Sbjct: 1446 LDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRE 1505
Query: 185 NKKLK----------LENGGLVRENLRLKAEVDNRSP--QKFGRFAVAAL---QSKVEQY 229
NK L+ E G + E ++K ++D+ Q A A+L + K+ +
Sbjct: 1506 NKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRI 1565
Query: 230 ERETNRLKKALERSDKYIEELESQVAQLK-NSSEEKEAMNSICQTALSADGKGSKGSEED 288
+ E N++K ++R I E + ++ QLK N E+M Q+ L A+ + S+
Sbjct: 1566 QLELNQVKSEIDRK---IAEKDEELDQLKRNHLRVVESM----QSTLDAEIR-SRNDALR 1617
Query: 289 VVSKNQGD 296
+ K +GD
Sbjct: 1618 IKKKMEGD 1625
Score = 34.3 bits (77), Expect = 0.42
Identities = 48/213 (22%), Positives = 92/213 (43%), Gaps = 38/213 (17%)
Query: 86 HLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLV----QGNQNED 141
H + T L K+ E +I +Q E+E++ + + E + K + ++ + Q+
Sbjct: 1721 HTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTS 1780
Query: 142 KHLVTDNPSKINPETVAEWKKKLRTANEIYEKV-KDDVDKLKEANKKLKLENG------- 193
HL + K +TV + + +L A ++ K K + KL+ ++L+ E
Sbjct: 1781 AHL--ERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNV 1838
Query: 194 ----GLVRENLRLK-----AEVDNRSPQKFGRFAVAALQSKVEQYERET----------- 233
GL + R+K E D ++ + + V LQ+KV+ Y+R+
Sbjct: 1839 EAVKGLRKHERRVKELTYQTEEDRKNILRL-QDLVDKLQTKVKAYKRQAEEAEEQSNVNL 1897
Query: 234 ---NRLKKALERSDKYIEELESQVAQLKNSSEE 263
+L+ LE + + + ESQV +L+ S E
Sbjct: 1898 AKFRKLQHELEEAKERADIAESQVNKLRVKSRE 1930
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 48.5 bits (114), Expect = 2e-05
Identities = 65/291 (22%), Positives = 123/291 (42%), Gaps = 45/291 (15%)
Query: 86 HLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLV 145
+++ ++ LL ++ + EI +E + L +N +L+S+++ + TLV N+D V
Sbjct: 676 YVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQ---TLVSEQPNKD---V 729
Query: 146 TDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRLKAE 205
+ K + E +KL+T E+ E V +E ++ EN L +E LKA+
Sbjct: 730 VEQMEKC----IQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAK 785
Query: 206 VDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSDKYIEELES--QVAQLKNSSEE 263
+++ + S VE+ LKK + D I+ +E + LK +++E
Sbjct: 786 QNDQ----------VSFASLVEE-------LKKVIHEKDGKIKSVEELLEAELLKVANKE 828
Query: 264 KEAMNSICQTALSADGKGSKGSEEDVVS------------KNQGDSARKQPGSSTSSSSH 311
K SI KG EE + + N G + + S +H
Sbjct: 829 KTVQLSITSKVQELQNL-LKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAH 887
Query: 312 LAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLDVTDTSMDT 362
+ + + L + SSA Q + L K K+ +++E ML ++ + +
Sbjct: 888 VQEVAQHNLKEASSASQFEELEIVL---KEKENELKRLEAMLKERESDLSS 935
Score = 36.2 bits (82), Expect = 0.11
Identities = 129/725 (17%), Positives = 270/725 (37%), Gaps = 108/725 (14%)
Query: 65 CKEIIGGTSESEPMLSHTVRKHLRKTR-------LELLHKEYEDEIDCLQKEVEELKSKN 117
CK++ ++ M++ R ++ TR LE H ++++I +E ++++ K
Sbjct: 355 CKQL------TQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKF 408
Query: 118 LSLESQIKTILDPLTLVQGNQNEDKHLVTDNPSKINPETVAEWKKK----LRTANEIYEK 173
+ Q++ + L G + V++ +++ + AE K R NE+ EK
Sbjct: 409 QQVREQMEAEIAHLKQENGILRD---AVSNTTNQLESKQSAELNKLRQDYARLVNELTEK 465
Query: 174 V----KDDVDK--LKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVE 227
+++V K ++A +LK++ R +++ + R+ + A LQSK
Sbjct: 466 TGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEH--EAAQQDLQSKFV 523
Query: 228 QYERET------------------NRLKKALERSDKYIEELESQVAQLKNSSEEKEAMNS 269
E E RL + +E K + + ES Q+++ E+ EA+ +
Sbjct: 524 AKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKA 583
Query: 270 ICQ---TALSADGKGSKGSEEDVVSKNQGDSARKQPGSSTSSSSHLAKPSSSRLCDTSSA 326
Q + ++A S +EE + D KQ S +S L D +
Sbjct: 584 QIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNM 643
Query: 327 R-------QESTSKADLNCSKNKDLYQEQVEVML-DVTDTSMDTYLEREWGNKPSDCVPY 378
Q+ + A+ + +L + Q V + D ++ L+ E NK +
Sbjct: 644 NFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKIL 703
Query: 379 KDEELYDLPAPCTPLSLSCLQLSTPENRESSVVQAGGSKKHSNHLRKLVFDDFCDSSNVS 438
D+ + LQ E VV+ + ++ ++ +
Sbjct: 704 NDQN------KALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQ 757
Query: 439 NKDSSED-DISRSENEKKSECFSSPKTGFWDCCSTSYAQNLDFESSEGNTIANSVGEISS 497
E+ + R+EN T Q+L + ++ + A+ V E+
Sbjct: 758 VATKEEELNAIRTENSS----------------LTKEVQDLKAKQNDQVSFASLVEELKK 801
Query: 498 KLSEKSGLCLSKRLNSIRSFEMNRTRTSSEASMDAAYLDKISELDSMMSESDNSKSPCNN 557
+ EK G K + + E+ + + E ++ + K+ EL +++ + +
Sbjct: 802 VIHEKDGKI--KSVEELLEAELLKV-ANKEKTVQLSITSKVQELQNLLKGKEEQMNTMKA 858
Query: 558 GFKSLDLDGLSKSSQGSEFLEEPDKL----EEKTELNLSKGSLTN--DQLENGSEWKPTS 611
+ + D + + EE + L +E + NL + S + ++LE + K
Sbjct: 859 VLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENE 918
Query: 612 FFLLSPSDQEMNEDFSLHSSSCPVTNEIKPPSCLFQTEFSQGILLSSSHRLFEDQRFGSS 671
L +E D SS + +++ + LF+++ Q L +++
Sbjct: 919 LKRLEAMLKERESDL---SSKTQLLQDVQDENKLFKSQIEQ--LKQQNYQQASSFPPHEE 973
Query: 672 LFKMSS----EMHSLHNHLQSPWSTSFVPEKRNKNVNQ----------STKRKIQSSLSS 717
L K+ S E+ L N L S K+N ++ + ST++ +Q ++
Sbjct: 974 LLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNK 1033
Query: 718 ASPSK 722
S +
Sbjct: 1034 TSKER 1038
Score = 33.1 bits (74), Expect = 0.93
Identities = 52/225 (23%), Positives = 99/225 (44%), Gaps = 33/225 (14%)
Query: 62 ENPCKEIIGGTSESEPMLSHTVRKHLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLE 121
E KE + GTS SE + LE KE ++ LQ E E+ KS E
Sbjct: 1076 EKKAKECMAGTSGSEEVKV-----------LEHKLKEADEMHTLLQLECEKYKSVLAETE 1124
Query: 122 SQIKTILDPLTLVQGNQNEDKHLVTDNPSKINPE----TVAEWK-KKLRTANEIYEKVKD 176
++ + V+ +N+ K V ++ I T +E + ++LR+ N+ E ++
Sbjct: 1125 GILQKLQRS---VEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRR 1181
Query: 177 DVDKLKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRL 236
+ + L+ +K ++E V E LKA+++ + + Q++ ++ + ++
Sbjct: 1182 EREHLEMELEKAEMERSTYVTEVRELKAQLNETLTK------LRTEQNERQKVAGDLHKA 1235
Query: 237 KKALERSDKYIEELESQVAQLKNS-------SEEKEAMN-SICQT 273
+++LE I + ++NS S EKE M+ S+ QT
Sbjct: 1236 QQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQT 1280
Score = 30.8 bits (68), Expect = 4.6
Identities = 36/199 (18%), Positives = 86/199 (43%), Gaps = 29/199 (14%)
Query: 67 EIIGGTSESEPMLSHTVRKHLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKT 126
E + + +E ML V K KE + +++ ++ E +E+ K L + + +
Sbjct: 1015 EAMEALASTEKMLQDKVNK---------TSKERQQQVEAVELEAKEVLKK-LFPKVSVPS 1064
Query: 127 ILDPLTLVQGNQNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANK 186
L + G + + K + E V + KL+ A+E++ ++ + +K K
Sbjct: 1065 NLSYGEWLHGFEKKAKECMAGTSGS---EEVKVLEHKLKEADEMHTLLQLECEKYKS--- 1118
Query: 187 KLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSDKY 246
+ E G++++ R + +N+ + KV++ + +++ + S++
Sbjct: 1119 -VLAETEGILQKLQRSVEQEENK------------WKVKVDESHKTIKQMQSSFTSSEQE 1165
Query: 247 IEELESQVAQLKNSSEEKE 265
+E L S+ ++N E+E
Sbjct: 1166 LERLRSENKDIENLRRERE 1184
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 48.5 bits (114), Expect = 2e-05
Identities = 70/344 (20%), Positives = 143/344 (41%), Gaps = 28/344 (8%)
Query: 62 ENPCKEIIGGTSESEPMLSHTVRKHLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLE 121
E KE+ E E M S V K K LE + +ID L+ + +++ + + E
Sbjct: 920 EAKVKELTERLEEEEEMNSELVAK---KRNLEDKCSSLKRDIDDLELTLTKVEKEKHATE 976
Query: 122 SQIKTILDPLTLVQGN----QNEDKHLVTDNPSKINPETVAEWKKK-LRTANEIYEKVKD 176
+++K + + +T ++ N E K L + ++ V E K L N E+ D
Sbjct: 977 NKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTD 1036
Query: 177 DVDKLKEANKKLKLENGGLVRE---NLRLKAE----VDNRSPQ-----KFGRFAVAALQS 224
D++ E KKL+ + R+ +L++ E ++N Q K F ++ LQ+
Sbjct: 1037 DLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQA 1096
Query: 225 KVEQYERETNRLKKALERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALS------AD 278
K++ + + + +K ++ IEELE ++ + E S L +
Sbjct: 1097 KIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEE 1156
Query: 279 GKGSKGSEEDVVSKNQGDSARKQPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLNC 338
G+ ++ ++ K + + + + ++ H A ++ R S + +L
Sbjct: 1157 ASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQR 1216
Query: 339 SKNKDLYQEQVEVMLDVTDTSMD-TYLEREWGNKPSDCVPYKDE 381
K K L +E+ E+ +++ D + + L + N C +D+
Sbjct: 1217 VKQK-LEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQ 1259
Score = 41.6 bits (96), Expect = 0.003
Identities = 64/296 (21%), Positives = 119/296 (40%), Gaps = 50/296 (16%)
Query: 89 KTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTDN 148
K +LE E + EID + +E L ++E +T+ D + ++ + L+ D
Sbjct: 1218 KQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHD- 1276
Query: 149 PSKINPETVAEWKKKLRTAN-EIYEKVKDDVDKLKEANKKLKLENGGLVRENLRLKAEVD 207
+N + K +L+T N E+ +V++ + + K + L ++ LK +++
Sbjct: 1277 ---LNMQ-----KARLQTQNGELSHRVEEKESLISQLTKSKQ----ALTQQLEELKRQME 1324
Query: 208 NRSPQKFGRFAVAALQSK-------VEQYERETN---RLKKALERSD--------KY--- 246
+ K ALQS EQYE E L++AL +++ KY
Sbjct: 1325 EETKAK--NAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETD 1382
Query: 247 -------IEELESQVAQ-LKNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSA 298
+EE + ++AQ L+ + E E NS C +L + +G ED++ +
Sbjct: 1383 AIQRTEELEEAKKKLAQRLQEAEENTETANSKC-ASLEKTKQRLQGEVEDLMRDLERSHT 1441
Query: 299 RKQPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLNCS----KNKDLYQEQVE 350
+ + D S A E+ K + S K ++ Y+E V+
Sbjct: 1442 ACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVD 1497
Score = 40.4 bits (93), Expect = 0.006
Identities = 61/232 (26%), Positives = 111/232 (47%), Gaps = 34/232 (14%)
Query: 67 EIIGGTSESEPMLSHTVRKHLRKTRLELLHK--EYEDEIDCL----QKEVEELKSKNLSL 120
E + G+ E E V+ L + + EL K E ++EI+ L Q+ E L+S L
Sbjct: 1549 EEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSV---L 1605
Query: 121 ESQIKTILDPLTL---VQGNQNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDD 177
+++I++ D L L ++G+ NE + + + ++ AE +K LRT + +
Sbjct: 1606 DAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQM-----AETQKHLRTVQGQLKDSQLH 1660
Query: 178 VDKLKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRL- 236
+D +N+ LK + + R N L E++ ++ +EQ ER T RL
Sbjct: 1661 LDDALRSNEDLKEQLAIVERRNGLLLEELEE-------------MKVALEQTER-TRRLS 1706
Query: 237 -KKALERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEE 287
++ L+ SD+ ++ L SQ L N+ ++ EA + CQ + + S+ +EE
Sbjct: 1707 EQELLDASDR-VQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEE 1757
Score = 38.5 bits (88), Expect = 0.022
Identities = 104/517 (20%), Positives = 191/517 (36%), Gaps = 99/517 (19%)
Query: 158 AEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRF 217
AE +K++ T E +E+ K+++ + + K+L+ + L++E L+ +V +
Sbjct: 847 AEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQS--------- 897
Query: 218 AVAALQSKVEQYERETNRLKKALERSDKYIEE---LESQVAQLKNSSEEKEAMNSICQTA 274
ET L A ER + I+ LE++V +L EE+E MNS
Sbjct: 898 --------------ETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNS----- 938
Query: 275 LSADGKGSKGSEEDVVSKNQGD-SARKQPGSSTSSSSHLAKPSSSRLCDTSSARQESTSK 333
+ K + ED S + D + + H + L + +A +E+ SK
Sbjct: 939 ---ELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISK 995
Query: 334 ADLNCSKNKDLYQEQVEVMLDVTDTSMDTYLEREWGNKPSDCVPYKDEELYDLPAPCTPL 393
+K K QE + LD D +E + N +++ DL
Sbjct: 996 ----LTKEKKSLQEAHQQTLD------DLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQE 1045
Query: 394 SLSCLQLSTPENR--------ESSVVQAGGSKKH-SNHLRKLVFDDFCDSSNVSNKDSSE 444
L + + + S++ K+ L+K F+ +S +
Sbjct: 1046 KKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFE-------LSQLQAKI 1098
Query: 445 DD--ISRSENEKKSECFSSPKTGFWDCCSTSYAQNLDFESSEGNTIANSVGEISSKLSEK 502
DD + + +KK + + + + E + +A + EIS +L E
Sbjct: 1099 DDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSD-LARELEEISERLEEA 1157
Query: 503 SGLCLSK-RLNSIRSFEMNRTRTSSE----------ASMDAAYLDKISELDSMMS----- 546
SG ++ +N R E + R E A++ D ++EL +
Sbjct: 1158 SGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRV 1217
Query: 547 ----ESDNSKSPCNNGFKSLDLDGLSKSSQGSE---------FLEEPDKLEEKT----EL 589
E + S+ + +++ LSKS E F E K E++T +L
Sbjct: 1218 KQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDL 1277
Query: 590 NLSKGSL--TNDQLENGSEWKPTSFFLLSPSDQEMNE 624
N+ K L N +L + E K + L+ S Q + +
Sbjct: 1278 NMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQ 1314
Score = 36.2 bits (82), Expect = 0.11
Identities = 42/192 (21%), Positives = 82/192 (42%), Gaps = 18/192 (9%)
Query: 92 LELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTDNPSK 151
LE + + E++ L +++E + +L+ + + L + Q D+ ++
Sbjct: 1418 LEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNF--DKVLAEWKQKLDESQAELEAAQ 1475
Query: 152 INPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRE------NLRLKAE 205
+++ K+R A YE+V D ++ L+ NK L+ E L + NL+ +
Sbjct: 1476 KESRSLSTELFKMRNA---YEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEK 1532
Query: 206 VDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERS------DKYIEELESQVAQLK- 258
Q+ VA + + E+ L+ LE S D+ + E + ++ QLK
Sbjct: 1533 TKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKR 1592
Query: 259 NSSEEKEAMNSI 270
NS EA+ S+
Sbjct: 1593 NSQRAAEALQSV 1604
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 48.5 bits (114), Expect = 2e-05
Identities = 55/260 (21%), Positives = 123/260 (47%), Gaps = 26/260 (10%)
Query: 67 EIIGGTSESEPMLSHTVRKH----LRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLES 122
EI E + ++ ++KH + +R + + +++ KE +EL+ K +L+S
Sbjct: 1743 EIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQS 1802
Query: 123 QIKTILDPLTLVQGNQNEDKHLVTDNPSKINP-ETVAEWKK-KLRTANEIYEKVKDDVDK 180
Q++ + + DK LV+ +KI ET E+++ +++ + ++K++++K
Sbjct: 1803 QVEFLEQSMV--------DKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEK 1854
Query: 181 L-KEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAA---------LQSKVEQYE 230
L +E ++++ EN +N RL+ ++ + + ++ G A L+ +E E
Sbjct: 1855 LTEERDQRIAAENREK-EQNKRLQRQLRD-TKEEMGELARKEAEASRKKHELEMDLESLE 1912
Query: 231 RETNRLKKALERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEEDVV 290
L+ L+ + K I +L++ + S E ++ +NS + + ++ + + +
Sbjct: 1913 AANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVKSWL 1972
Query: 291 SKNQGDSARKQPGSSTSSSS 310
SKN+G S S SSS
Sbjct: 1973 SKNKGPSKAASDDGSLKSSS 1992
Score = 40.8 bits (94), Expect = 0.004
Identities = 43/186 (23%), Positives = 81/186 (43%), Gaps = 21/186 (11%)
Query: 140 EDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRE- 198
ED HL D+ +K + + R NEI ++++D + + E KK K R+
Sbjct: 1714 EDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDL 1773
Query: 199 ----NLRLKAEVDNRSPQKFGRFAVAALQSKVE-------------QYERETNRLKKALE 241
+L+ + E N+ Q+ + + ALQS+VE + E + L+ LE
Sbjct: 1774 AQINDLQAQLEEANKEKQEL-QEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLE 1832
Query: 242 RSDKYIEELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEEDV--VSKNQGDSAR 299
++ LES ++LK + E+ A + + + +K + + + G+ AR
Sbjct: 1833 FERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELAR 1892
Query: 300 KQPGSS 305
K+ +S
Sbjct: 1893 KEAEAS 1898
Score = 36.2 bits (82), Expect = 0.11
Identities = 100/553 (18%), Positives = 208/553 (37%), Gaps = 87/553 (15%)
Query: 99 YEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTDNPSKINPETVA 158
+ ++ L+ E++++ S+ E+ + + L ++ + + + + I A
Sbjct: 1512 FTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQA 1571
Query: 159 ------EWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRLKAEVDNRSPQ 212
E ++ +T ++ E ++V++ +++ +K + + E K +V +
Sbjct: 1572 KLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRE 1631
Query: 213 KFGRFAVAALQSKVEQYERETNRLKKALERSDKYIEELESQVAQLKNSSEEK-------- 264
G+ A + Q +E E RL+K L+R+ + + + + LKNS+ K
Sbjct: 1632 LEGKLATLSDQVNRRDFESE-KRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKN 1690
Query: 265 --EAMNSICQTALSA----------------DGKGSKGSEEDVVSKNQGD--SARKQPGS 304
E C A+ A D +K + E+ +S+ Q + + +
Sbjct: 1691 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEE 1750
Query: 305 STSSSSHLAKPSSSRLCDTS---------SARQESTSKADLNCSKNKDLYQEQVEV---- 351
+ L K + + S A+ E +K + Q QVE
Sbjct: 1751 DQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQS 1810
Query: 352 MLDVTDTSMDTYLEREWGNKPSDCVPYKDEELYDLPAPCTPLSLSCLQLSTPENRESSVV 411
M+D + S RE + + ++ ++ L + + L + +L+ E R+ +
Sbjct: 1811 MVDKSLVSRQEAKIRELETR----LEFERTQVKRLESLASRLKENMEKLT--EERDQRIA 1864
Query: 412 QAGGSKKHSNHLRKLVFDDFCDSSNVSNKDSSEDDISRSENEKKSECFS----------S 461
K+ + L++ + D + ++ K E + SR ++E + + S
Sbjct: 1865 AENREKEQNKRLQRQLRDTKEEMGELARK---EAEASRKKHELEMDLESLEAANQSLQAD 1921
Query: 462 PKTGFWDCCSTSYAQNLDFESSEGNTIANSVGEISSKLSEKSGLCLSKRLNSIRSFEMNR 521
K F A + ES E + NS G+ S SE L R++ ++S+ +++
Sbjct: 1922 LKLAFKRIGDLQAAIEDEMESDENEDLINSEGD-SDVDSE-----LEDRVDGVKSW-LSK 1974
Query: 522 TRTSSEASMDAAYLDKISELDSMMS----ESDNSKSPCNNGFKSLDLDGLSKSSQGSEFL 577
+ S+A+ D L S S SD+ P LD S+ +L
Sbjct: 1975 NKGPSKAASDDGSLKSSSPTSYWKSLAPDRSDDEHDP---------LDNTSRPRYSHSYL 2025
Query: 578 EEPDKLEEKTELN 590
+ D + TE N
Sbjct: 2026 SDSDTEAKLTETN 2038
Score = 33.9 bits (76), Expect = 0.55
Identities = 75/392 (19%), Positives = 144/392 (36%), Gaps = 43/392 (10%)
Query: 219 VAALQSKVEQYERETNRLKKALERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALSAD 278
+ L+SK+E+ E+E N L+ +R + I EL S++ +N+ E S Q +
Sbjct: 1263 IQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGE------SASQLLDAET 1316
Query: 279 GKGSKGSEEDVVSKNQGDSARKQ---PGSSTSSSSHLAKPSSSRLCDTSSARQE---STS 332
+ + +E + Q D+ +KQ + + + D A E
Sbjct: 1317 AERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYE 1376
Query: 333 KADLNCSKNKDLYQEQVEVMLDVTDTSMDTYLEREWGNKPSDCVPYKDEELYDLPAPCTP 392
+A K Q++ E L+V + LER G+ +D L L C
Sbjct: 1377 RAVREVDFTKKRLQQEFEDKLEV-EQQNKRQLERRLGDLQADS-EESQRALQQLKKKC-- 1432
Query: 393 LSLSCLQLSTPENRESSVVQAGGS-KKHSNHLRKLVFDDFCDSSN--VSNKDSSEDDISR 449
Q T E +++ + G + H ++ FD ++ + + + R
Sbjct: 1433 ------QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQR 1486
Query: 450 SENEKKSECFSSPK---------TGFWDCCSTSYAQNLDFESSEGNTIANSVGEISSKLS 500
++ +E FS + GF + A+ D S E A S+ ++ +L
Sbjct: 1487 EKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEA-SLAKVKKQLR 1545
Query: 501 EKSGLC------LSKRLNSIRSFEMNRTRTSSEASMDAAYLDKISELDSMMSESDNSKSP 554
+ L ++ +I+ E + R E M+ E++S E + ++
Sbjct: 1546 DLEAKVKDQEEELDEQAGTIQMLEQAKLRL--EMEMERMRQTHSKEMESRDEEVEEARQS 1603
Query: 555 CNNGFKSLDLDGLSKSSQGSEFLEEPDKLEEK 586
C K +++ + + L E +LE K
Sbjct: 1604 CQKKLKQMEVQLEEEYEDKQKVLREKRELEGK 1635
Score = 32.0 bits (71), Expect = 2.1
Identities = 55/229 (24%), Positives = 99/229 (43%), Gaps = 35/229 (15%)
Query: 97 KEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTDNPSKINPET 156
++ +++ +KE EL+ + LES+I + LT + N E + D
Sbjct: 1264 QQLRSKLEKAEKERNELRLNSDRLESRISELTSELT-DERNTGESASQLLD--------- 1313
Query: 157 VAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLE--NGGLVRENLRLKAEVDNRSPQKF 214
AE ++LR E+ E ++ D LK+ + +++E L+R + EVD+
Sbjct: 1314 -AETAERLRAEKEMKE-LQTQYDALKKQMEVMEMEVMEARLIRA-AEINGEVDDDD---- 1366
Query: 215 GRFAVAALQSKVEQYERETNRLKKALER--SDKYIEE------LESQVAQLKNSSEEK-- 264
A + K E+ RE + KK L++ DK E LE ++ L+ SEE
Sbjct: 1367 ---AGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR 1423
Query: 265 --EAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARKQPGSSTSSSSH 311
+ + CQ L+A+ + +K E +N +++ S S +H
Sbjct: 1424 ALQQLKKKCQ-RLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAH 1471
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 48.1 bits (113), Expect = 3e-05
Identities = 102/531 (19%), Positives = 207/531 (38%), Gaps = 67/531 (12%)
Query: 74 ESEPML--SHTVRKHLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLE---SQIKTIL 128
E+EP+ H V + ++ ++K+YE E L +EEL++K + +E S +K +
Sbjct: 605 ETEPVKLGGHQVAESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNM 664
Query: 129 DPLTLVQGNQNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKL 188
T E+ N SK+ E + + L ++ EK+ V A K
Sbjct: 665 AHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKI---VAYSSIAAKNA 721
Query: 189 KLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSDKYIE 248
+LE L+ +N ++++ N + + + +A ++K E+ + +K IE
Sbjct: 722 ELEQE-LMEKNEKIRSLETNINTEH-EKICLAFEKAKKIHLEQH--------KEMEKQIE 771
Query: 249 ELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARKQPGSSTSS 308
LE+Q+ + +E+E S+ Q +D++ K S
Sbjct: 772 RLEAQLEKKDQQFKEQEKTMSMLQ--------------QDIICKQH----------HLES 807
Query: 309 SSHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLDVTDTSMDTYLEREW 368
L S + + +++ KA N + + Q++ L++ + +L +
Sbjct: 808 LDRLLTESKGEM-KKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLE 866
Query: 369 GNKP--SDCVPYKDEELYDLPAPCTPLSLSCLQLSTPENRESSVVQAGGSKKHSNHLRKL 426
GNK + K EE+Y C L S E E +V+ ++ L++
Sbjct: 867 GNKEKFEKQLKKKSEEVY-----CLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQ- 920
Query: 427 VFDDFCDSSNVSNKDSSEDDISRSENE-KKSECFSSPKTGFWDCCSTSYAQNLDFESSEG 485
+ + + E +S+ E E +K S+ K + S A D + +
Sbjct: 921 --ETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKV 978
Query: 486 NTIANSVGEISSKLSEKSGLCLSKRLNSIRSFEMNRTRTSSEASMDAAYLDKISELDSMM 545
+ + ++ ++ + + L+ + M+ R +M +S+LD ++
Sbjct: 979 IELTGTARQVKIEMDQ-----YKEELSKMEKEIMHLKRDGENKAM------HLSQLDMIL 1027
Query: 546 SESDNSKSPCNNGFKSLDLDGLSKSSQGSEFLEEPDKLEEKTELNLSKGSL 596
++ N K L+ S ++ +E L++ + LE TEL + G L
Sbjct: 1028 DQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLE--TELQNAHGEL 1076
Score = 43.5 bits (101), Expect = 7e-04
Identities = 53/218 (24%), Positives = 102/218 (46%), Gaps = 18/218 (8%)
Query: 63 NPCKEIIGGTSESEPMLSHTVRKH-LRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLE 121
N KE+ +E L+ ++K + +T L+ H E + + LQ+ + L+ LSLE
Sbjct: 1039 NAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLE 1098
Query: 122 SQIKTILDPLTLVQGNQNEDKHLVTDNPSKINPETVA----EWKKKLRTANEIYEKVKDD 177
+ TI D + E K + D ++ A W+ K R A + +
Sbjct: 1099 EKYTTIKD----LTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIR 1154
Query: 178 VDKLKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQY-----ERE 232
+ + K +KLE G L + L LK E + + + A Q + +++ E+E
Sbjct: 1155 EHRGEMEQKIIKLE-GTLEKSELELK-ECNKQIESLNDKLQNAKEQLREKEFIMLQNEQE 1212
Query: 233 TNRLKKALERSDKYIEELESQVAQLKN--SSEEKEAMN 268
++LKK +ER+ + ++E+ES + + + +++ KEA++
Sbjct: 1213 ISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAID 1250
Score = 35.4 bits (80), Expect = 0.19
Identities = 59/264 (22%), Positives = 99/264 (37%), Gaps = 30/264 (11%)
Query: 106 LQKEVEELKSKNLSLESQI--------KTILDPLTLVQGNQNEDKHLVTDNPSKINPETV 157
LQ EEL S + S S K ILD G N + +N KI+ +
Sbjct: 154 LQSLGEELSSVSPSENSDYAPNPSRSEKLILDVQPSHPGLLNYSPY---ENVCKISGSST 210
Query: 158 AEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRLKAEVDN-RSPQKFGR 216
KK V ++ L+E KL+ +N LV +N L + ++ R
Sbjct: 211 DFQKKPRDKMFSSSAPVDQEIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSR 270
Query: 217 FAVAALQSKVEQ------YERETNRLKKALERSDKYIEELESQVAQLKNSSEEKEAMNSI 270
V+ L+S +Q E + L+ + DK + E E+++ Q + EKE
Sbjct: 271 AKVSMLESAQQQAASVPILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKE----- 325
Query: 271 CQTALSADGKGSKGSEEDVVSKNQGDSARKQPGSSTSSSSHLA------KPSSSRLCDTS 324
Q+ + + K + + QG A +Q + ++ L+ K + +
Sbjct: 326 -QSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKV 384
Query: 325 SARQESTSKADLNCSKNKDLYQEQ 348
A +E + NC K QE+
Sbjct: 385 QAEEEILERNLTNCEKENKRLQER 408
>gi|122891870 melanoma inhibitory activity family, member 3 [Homo
sapiens]
Length = 1907
Score = 47.8 bits (112), Expect = 4e-05
Identities = 53/235 (22%), Positives = 100/235 (42%), Gaps = 28/235 (11%)
Query: 85 KHLRKTRLELLHK--EYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQ---- 138
K + K EL+ K YE +I +K V+E + +N+ L + D + ++ NQ
Sbjct: 1221 KTIMKENTELVQKLSNYEQKIKESKKHVQETRKQNMILSDEAIKYKDKIKTLEKNQEILD 1280
Query: 139 ----NEDKHLVTDNPSKI-NPETVAEWKKKLRTANEI-------YEKVKDDVDKLKEANK 186
N L ++ + N + ++E KK + ++ + +V+ +++ K + +
Sbjct: 1281 DTAKNLRVMLESEREQNVKNQDLISENKKSIEKLKDVISMNASEFSEVQIALNEAKLSEE 1340
Query: 187 KLKLENGGLVRENLRLKAEVDNRSPQ-KFGRFAVAALQSKVEQYERETNRLKKALERSDK 245
K+K E + EN RLK + + + + A L +++ +E+ L+ AL D
Sbjct: 1341 KVKSECHRVQEENARLKKKKEQLQQEIEDWSKLHAELSEQIKSFEKSQKDLEVALTHKDD 1400
Query: 246 YIEELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARK 300
I L + + QL N E C++ KG S+E + GD K
Sbjct: 1401 NINALTNCITQL-NLLE--------CESESEGQNKGGNDSDELANGEVGGDRNEK 1446
>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
Length = 898
Score = 47.8 bits (112), Expect = 4e-05
Identities = 69/323 (21%), Positives = 140/323 (43%), Gaps = 37/323 (11%)
Query: 66 KEIIGGTSESEPMLSHTVRKHLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIK 125
K++ E E + + K RL L++ E E L +E+++LK S ++K
Sbjct: 334 KKLRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVK 393
Query: 126 TILDPLTLVQGNQNEDKHLVTDNPSKINP--ETVAEWKKK----LRTANEIYEKVKDDVD 179
+ L + E K + + +K+ E + +K ++T E E +++D
Sbjct: 394 WAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELD 453
Query: 180 -KLK----EANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVE------- 227
KL+ E K+++ ++ L + ++K D + K G + L++KV+
Sbjct: 454 AKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERL 513
Query: 228 -------QYERETNRLKKALER-------SDKYIEELESQVAQLKNSSEEKEAMNSICQT 273
+Y+ NR K ++ +D+ E+L+ +++N EE E++NS+
Sbjct: 514 RTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVESLNSLIND 573
Query: 274 ALSADGKGSKGSEEDVVSKNQGDSARKQPGSSTSSS--SHLAKPSSSRLCDTSSARQEST 331
L D +GS+ E +++ + +++ S S+S S K S S S Q
Sbjct: 574 -LQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCSESQLQSQCEQMKQ 632
Query: 332 SKADLNCS--KNKDLYQEQVEVM 352
+ +L K ++L +E+V+ +
Sbjct: 633 TNINLESRLLKEEELRKEEVQTL 655
Score = 45.8 bits (107), Expect = 1e-04
Identities = 49/218 (22%), Positives = 105/218 (48%), Gaps = 28/218 (12%)
Query: 65 CKEIIGGTSESEPMLSHTVRKHLRKTRLELLHKEYEDEIDCLQ------KEVEELK---- 114
C+++I ESE + S+ + LR T+ E L K+ +++ D L+ KE+E+LK
Sbjct: 434 CQDMIKTYQESEEIKSNELDAKLRVTKGE-LEKQMQEKSDQLEMHHAKIKELEDLKRTFK 492
Query: 115 ---SKNLSLESQIKTILDPLTLVQGNQNEDKHLVTDNPSKINPETVAEWKKKLRTANEIY 171
+ +L +++K + D + ++ K ++ ++I K++TA+++
Sbjct: 493 EGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQ-----NLLDKVKTADQLQ 547
Query: 172 EKV---KDDVDKLKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQ 228
E++ K +++ LKE ++E+ + +L+ E + + F L SK Q
Sbjct: 548 EQLQRGKQEIENLKE-----EVESLNSLINDLQKDIEGSRKRESELLLF-TERLTSKNAQ 601
Query: 229 YERETNRLKKALERSDKYIEELESQVAQLKNSSEEKEA 266
+ E+N L+ ++ +L+SQ Q+K ++ E+
Sbjct: 602 LQSESNSLQSQFDKVSCSESQLQSQCEQMKQTNINLES 639
Score = 42.0 bits (97), Expect = 0.002
Identities = 46/224 (20%), Positives = 95/224 (42%), Gaps = 25/224 (11%)
Query: 159 EWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFA 218
E KK+ T + +K +++E NK++K L+ +++ K V + R
Sbjct: 236 ELKKRTETEKQHMNTIKQLESRIEELNKEVKASRDQLIAQDVTAKNAVQQLHKEMAQRME 295
Query: 219 VA------------ALQSKVEQYERETNRLKKALERSDKYI----EELESQVAQLKNSSE 262
A A+ K + E+E+ L+K E +K + +ELE ++K S+
Sbjct: 296 QANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQ 355
Query: 263 EKEAMNSICQTALSADGKGSKGSEE-DVVSKNQGDSARKQPGSSTSSSSHL--AKPSSSR 319
EK ++ + +T +G+ ++ E D + ++ K + + + K + +
Sbjct: 356 EKGRLHQLYET---KEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKDK 412
Query: 320 LCDTSSARQESTSKAD---LNCSKNKDLYQEQVEVMLDVTDTSM 360
L +T++ ++ +AD NC YQE E+ + D +
Sbjct: 413 LKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKL 456
>gi|158186614 transmembrane protein 118 isoform 1 [Homo sapiens]
Length = 444
Score = 47.8 bits (112), Expect = 4e-05
Identities = 18/39 (46%), Positives = 23/39 (58%)
Query: 18 CHICLGKVRQPVICINNHVFCSICIDLWLKNNSQCPACR 56
C IC + R+P+I + HVFC C+ LWL CP CR
Sbjct: 384 CAICQAEFREPLILLCQHVFCEECLCLWLDRERTCPLCR 422
>gi|109134327 PTD016 protein [Homo sapiens]
Length = 435
Score = 47.4 bits (111), Expect = 5e-05
Identities = 16/43 (37%), Positives = 24/43 (55%)
Query: 18 CHICLGKVRQPVICINNHVFCSICIDLWLKNNSQCPACRVPIT 60
C IC + ++P++ I H+FC C+ LW CP CR I+
Sbjct: 375 CSICQAEFQKPILLICQHIFCEECMTLWFNREKTCPLCRTVIS 417
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 47.0 bits (110), Expect = 6e-05
Identities = 64/300 (21%), Positives = 127/300 (42%), Gaps = 40/300 (13%)
Query: 86 HLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLV 145
+++ ++ LL ++ + EI +E + L +N +L+S+++ + TLV N+D V
Sbjct: 676 YVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQ---TLVSEQPNKD---V 729
Query: 146 TDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRLKAE 205
+ K + E +KL+T E+ E V +E ++ EN L +E LKA+
Sbjct: 730 VEQMEKC----IQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAK 785
Query: 206 VDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALE-------RSDKYIEELESQVAQLK 258
++ Q V L+ + + + + +++ LE +K +++L+ ++ LK
Sbjct: 786 ---QNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALK 842
Query: 259 ----NSSEEKEAMNSICQTALSADGKGSKGSEEDVVS------------KNQGDSARKQP 302
N EK SI KG EE + + N G +
Sbjct: 843 EEIGNVQLEKAQQLSITSKVQELQNL-LKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQ 901
Query: 303 GSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLDVTDTSMDT 362
+ S +H+ + + L + SSA Q + L K K+ +++E ML ++ + +
Sbjct: 902 EENESLKAHVQEVAQHNLKEASSASQFEELEIVL---KEKENELKRLEAMLKERESDLSS 958
Score = 35.0 bits (79), Expect = 0.25
Identities = 56/308 (18%), Positives = 128/308 (41%), Gaps = 39/308 (12%)
Query: 65 CKEIIGGTSESEPMLSHTVRKHLRKTR-------LELLHKEYEDEIDCLQKEVEELKSKN 117
CK++ ++ M++ R ++ TR LE H ++++I +E ++++ K
Sbjct: 355 CKQL------TQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKF 408
Query: 118 LSLESQIKTILDPLTLVQGNQNEDKHLVTDNPSKINPETVAEWKKK----LRTANEIYEK 173
+ Q++ + L G + V++ +++ + AE K R NE+ EK
Sbjct: 409 QQVREQMEAEIAHLKQENGILRD---AVSNTTNQLESKQSAELNKLRQDYARLVNELTEK 465
Query: 174 V----KDDVDK--LKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVE 227
+++V K ++A +LK++ R +++ + R+ + A LQSK
Sbjct: 466 TGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEH--EAAQQDLQSKFV 523
Query: 228 QYERETNRLKKALERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEE 287
E E L L + ++LE ++ QL S +++ Q + +
Sbjct: 524 AKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQV-----------Q 572
Query: 288 DVVSKNQGDSARKQPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQE 347
D++ +N+ A+ Q S ++ A + L + + + + + + + +D
Sbjct: 573 DILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTS 632
Query: 348 QVEVMLDV 355
+ E + D+
Sbjct: 633 KEEELKDI 640
Score = 30.8 bits (68), Expect = 4.6
Identities = 36/199 (18%), Positives = 86/199 (43%), Gaps = 29/199 (14%)
Query: 67 EIIGGTSESEPMLSHTVRKHLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKT 126
E + + +E ML V K KE + +++ ++ E +E+ K L + + +
Sbjct: 1038 EAMEALASTEKMLQDKVNK---------TSKERQQQVEAVELEAKEVLKK-LFPKVSVPS 1087
Query: 127 ILDPLTLVQGNQNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANK 186
L + G + + K + E V + KL+ A+E++ ++ + +K K
Sbjct: 1088 NLSYGEWLHGFEKKAKECMAGTSGS---EEVKVLEHKLKEADEMHTLLQLECEKYKS--- 1141
Query: 187 KLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSDKY 246
+ E G++++ R + +N+ + KV++ + +++ + S++
Sbjct: 1142 -VLAETEGILQKLQRSVEQEENK------------WKVKVDESHKTIKQMQSSFTSSEQE 1188
Query: 247 IEELESQVAQLKNSSEEKE 265
+E L S+ ++N E+E
Sbjct: 1189 LERLRSENKDIENLRRERE 1207
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 47.0 bits (110), Expect = 6e-05
Identities = 64/300 (21%), Positives = 127/300 (42%), Gaps = 40/300 (13%)
Query: 86 HLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLV 145
+++ ++ LL ++ + EI +E + L +N +L+S+++ + TLV N+D V
Sbjct: 676 YVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQ---TLVSEQPNKD---V 729
Query: 146 TDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRLKAE 205
+ K + E +KL+T E+ E V +E ++ EN L +E LKA+
Sbjct: 730 VEQMEKC----IQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAK 785
Query: 206 VDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALE-------RSDKYIEELESQVAQLK 258
++ Q V L+ + + + + +++ LE +K +++L+ ++ LK
Sbjct: 786 ---QNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALK 842
Query: 259 ----NSSEEKEAMNSICQTALSADGKGSKGSEEDVVS------------KNQGDSARKQP 302
N EK SI KG EE + + N G +
Sbjct: 843 EEIGNVQLEKAQQLSITSKVQELQNL-LKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQ 901
Query: 303 GSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLDVTDTSMDT 362
+ S +H+ + + L + SSA Q + L K K+ +++E ML ++ + +
Sbjct: 902 EENESLKAHVQEVAQHNLKEASSASQFEELEIVL---KEKENELKRLEAMLKERESDLSS 958
Score = 35.0 bits (79), Expect = 0.25
Identities = 56/308 (18%), Positives = 128/308 (41%), Gaps = 39/308 (12%)
Query: 65 CKEIIGGTSESEPMLSHTVRKHLRKTR-------LELLHKEYEDEIDCLQKEVEELKSKN 117
CK++ ++ M++ R ++ TR LE H ++++I +E ++++ K
Sbjct: 355 CKQL------TQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKF 408
Query: 118 LSLESQIKTILDPLTLVQGNQNEDKHLVTDNPSKINPETVAEWKKK----LRTANEIYEK 173
+ Q++ + L G + V++ +++ + AE K R NE+ EK
Sbjct: 409 QQVREQMEAEIAHLKQENGILRD---AVSNTTNQLESKQSAELNKLRQDYARLVNELTEK 465
Query: 174 V----KDDVDK--LKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVE 227
+++V K ++A +LK++ R +++ + R+ + A LQSK
Sbjct: 466 TGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEH--EAAQQDLQSKFV 523
Query: 228 QYERETNRLKKALERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEE 287
E E L L + ++LE ++ QL S +++ Q + +
Sbjct: 524 AKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQV-----------Q 572
Query: 288 DVVSKNQGDSARKQPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQE 347
D++ +N+ A+ Q S ++ A + L + + + + + + + +D
Sbjct: 573 DILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTS 632
Query: 348 QVEVMLDV 355
+ E + D+
Sbjct: 633 KEEELKDI 640
Score = 33.1 bits (74), Expect = 0.93
Identities = 52/225 (23%), Positives = 99/225 (44%), Gaps = 33/225 (14%)
Query: 62 ENPCKEIIGGTSESEPMLSHTVRKHLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLE 121
E KE + GTS SE + LE KE ++ LQ E E+ KS E
Sbjct: 1070 EKKAKECMAGTSGSEEVKV-----------LEHKLKEADEMHTLLQLECEKYKSVLAETE 1118
Query: 122 SQIKTILDPLTLVQGNQNEDKHLVTDNPSKINPE----TVAEWK-KKLRTANEIYEKVKD 176
++ + V+ +N+ K V ++ I T +E + ++LR+ N+ E ++
Sbjct: 1119 GILQKLQRS---VEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRR 1175
Query: 177 DVDKLKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRL 236
+ + L+ +K ++E V E LKA+++ + + Q++ ++ + ++
Sbjct: 1176 EREHLEMELEKAEMERSTYVTEVRELKAQLNETLTK------LRTEQNERQKVAGDLHKA 1229
Query: 237 KKALERSDKYIEELESQVAQLKNS-------SEEKEAMN-SICQT 273
+++LE I + ++NS S EKE M+ S+ QT
Sbjct: 1230 QQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSLNQT 1274
Score = 30.4 bits (67), Expect = 6.1
Identities = 34/182 (18%), Positives = 76/182 (41%), Gaps = 33/182 (18%)
Query: 101 DEIDCLQKEVEELKSKNLSLESQIKTI----------LDPLTLVQGNQNE-------DKH 143
+E+D L+ VE + KN + Q++ + L P V N + +K
Sbjct: 1013 NELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKK 1072
Query: 144 LVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRLK 203
E V + KL+ A+E++ ++ + +K K + E G++++ R
Sbjct: 1073 AKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKS----VLAETEGILQKLQRSV 1128
Query: 204 AEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSDKYIEELESQVAQLKNSSEE 263
+ +N+ + KV++ + +++ + S++ +E L S+ ++N E
Sbjct: 1129 EQEENK------------WKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRRE 1176
Query: 264 KE 265
+E
Sbjct: 1177 RE 1178
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 47.0 bits (110), Expect = 6e-05
Identities = 64/300 (21%), Positives = 127/300 (42%), Gaps = 40/300 (13%)
Query: 86 HLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLV 145
+++ ++ LL ++ + EI +E + L +N +L+S+++ + TLV N+D V
Sbjct: 676 YVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQ---TLVSEQPNKD---V 729
Query: 146 TDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRLKAE 205
+ K + E +KL+T E+ E V +E ++ EN L +E LKA+
Sbjct: 730 VEQMEKC----IQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAK 785
Query: 206 VDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALE-------RSDKYIEELESQVAQLK 258
++ Q V L+ + + + + +++ LE +K +++L+ ++ LK
Sbjct: 786 ---QNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALK 842
Query: 259 ----NSSEEKEAMNSICQTALSADGKGSKGSEEDVVS------------KNQGDSARKQP 302
N EK SI KG EE + + N G +
Sbjct: 843 EEIGNVQLEKAQQLSITSKVQELQNL-LKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQ 901
Query: 303 GSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLDVTDTSMDT 362
+ S +H+ + + L + SSA Q + L K K+ +++E ML ++ + +
Sbjct: 902 EENESLKAHVQEVAQHNLKEASSASQFEELEIVL---KEKENELKRLEAMLKERESDLSS 958
Score = 35.0 bits (79), Expect = 0.25
Identities = 56/308 (18%), Positives = 128/308 (41%), Gaps = 39/308 (12%)
Query: 65 CKEIIGGTSESEPMLSHTVRKHLRKTR-------LELLHKEYEDEIDCLQKEVEELKSKN 117
CK++ ++ M++ R ++ TR LE H ++++I +E ++++ K
Sbjct: 355 CKQL------TQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQMQMKF 408
Query: 118 LSLESQIKTILDPLTLVQGNQNEDKHLVTDNPSKINPETVAEWKKK----LRTANEIYEK 173
+ Q++ + L G + V++ +++ + AE K R NE+ EK
Sbjct: 409 QQVREQMEAEIAHLKQENGILRD---AVSNTTNQLESKQSAELNKLRQDYARLVNELTEK 465
Query: 174 V----KDDVDK--LKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVE 227
+++V K ++A +LK++ R +++ + R+ + A LQSK
Sbjct: 466 TGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEH--EAAQQDLQSKFV 523
Query: 228 QYERETNRLKKALERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEE 287
E E L L + ++LE ++ QL S +++ Q + +
Sbjct: 524 AKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQV-----------Q 572
Query: 288 DVVSKNQGDSARKQPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQE 347
D++ +N+ A+ Q S ++ A + L + + + + + + + +D
Sbjct: 573 DILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTS 632
Query: 348 QVEVMLDV 355
+ E + D+
Sbjct: 633 KEEELKDI 640
Score = 30.8 bits (68), Expect = 4.6
Identities = 36/199 (18%), Positives = 86/199 (43%), Gaps = 29/199 (14%)
Query: 67 EIIGGTSESEPMLSHTVRKHLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKT 126
E + + +E ML V K KE + +++ ++ E +E+ K L + + +
Sbjct: 1038 EAMEALASTEKMLQDKVNK---------TSKERQQQVEAVELEAKEVLKK-LFPKVSVPS 1087
Query: 127 ILDPLTLVQGNQNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANK 186
L + G + + K + E V + KL+ A+E++ ++ + +K K
Sbjct: 1088 NLSYGEWLHGFEKKAKECMAGTSGS---EEVKVLEHKLKEADEMHTLLQLECEKYKS--- 1141
Query: 187 KLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSDKY 246
+ E G++++ R + +N+ + KV++ + +++ + S++
Sbjct: 1142 -VLAETEGILQKLQRSVEQEENK------------WKVKVDESHKTIKQMQSSFTSSEQE 1188
Query: 247 IEELESQVAQLKNSSEEKE 265
+E L S+ ++N E+E
Sbjct: 1189 LERLRSENKDIENLRRERE 1207
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 47.0 bits (110), Expect = 6e-05
Identities = 48/224 (21%), Positives = 102/224 (45%), Gaps = 41/224 (18%)
Query: 101 DEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTDN--------PSKI 152
++++ L+ E + L+ +N +L + T+ + ++G + ++K L +N +
Sbjct: 659 EKVEALEHESQGLQLENRTLRKSLDTLQNVSLQLEGLERDNKQLDAENLELRRLVETMRF 718
Query: 153 NPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKK---LKLENGGLVRENLRLKAEVDNR 209
+A+ +++ + E+++ +VD LK KK L+L + ENLRL+ +++
Sbjct: 719 TSTKLAQMERENQQLEREKEELRKNVDLLKALGKKSERLELSYQSVSAENLRLQQSLESS 778
Query: 210 SPQKFGRFAVAALQSKVEQYERETNRLKKALER----------SDKYIEELESQVAQLKN 259
S + L+S++ + E E L++ LE ++K + LE +VAQL+
Sbjct: 779 SHK------TQTLESELGELEAERQALRRDLEALRLANAQLEGAEKDRKALEQEVAQLEK 832
Query: 260 SS--------------EEKEAMNSICQTALSADGKGSKGSEEDV 289
E K+A+ LSA K S+ ++++
Sbjct: 833 DKKLLEKEAKRLWQQVELKDAVLDDSTAKLSAVEKESRALDKEL 876
Score = 39.7 bits (91), Expect = 0.010
Identities = 40/184 (21%), Positives = 89/184 (48%), Gaps = 38/184 (20%)
Query: 104 DCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTDNPSKINPETVAEWKKK 163
+C + +L+ +N SL+S I+ + D +++ + + L +N + KK
Sbjct: 459 ECASSRILKLEKENQSLQSTIQGLRDASLVLEESGLKCGELEKENH---------QLSKK 509
Query: 164 LRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQ 223
+ EK++ +++ K++N+ L+ + L+RE +L+++++ K
Sbjct: 510 I-------EKLQTQLEREKQSNQDLETLSEELIREKEQLQSDMETLKADK---------A 553
Query: 224 SKVEQYERETNRLKKAL----ERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALSADG 279
+++ E+E + L +A+ ERS S A++K+ +E +A++ QT A+G
Sbjct: 554 RQIKDLEQEKDHLNRAMWSLRERSQ------VSSEARMKDVEKENKALH---QTVTEANG 604
Query: 280 KGSK 283
K S+
Sbjct: 605 KLSQ 608
Score = 35.8 bits (81), Expect = 0.14
Identities = 41/179 (22%), Positives = 71/179 (39%), Gaps = 6/179 (3%)
Query: 100 EDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTD-----NPSKINP 154
E++I L+ ++EE S N LES+++ + ++ NQ E +HL + +
Sbjct: 976 EEKIVLLEAQMEEKASLNRQLESELQMLKKECETLRQNQGEGQHLQNSFKHPAGKTAASH 1035
Query: 155 ETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRLKAEVDNRSPQKF 214
+ W + A +VKD +L+ N L+ E L + L+ + S Q
Sbjct: 1036 QGKEAWGPGHKEATMELLRVKDRAIELERNNAALQAEKQLLKEQLQHLETQNVTFSSQIL 1095
Query: 215 G-RFAVAALQSKVEQYERETNRLKKALERSDKYIEELESQVAQLKNSSEEKEAMNSICQ 272
+ A LQ + +T +L+ L +Q L+N KE N Q
Sbjct: 1096 TLQKQSAFLQEHNTTLQTQTAKLQVENSTLSSQSAALTAQYTLLQNHHTAKETENESLQ 1154
Score = 34.7 bits (78), Expect = 0.32
Identities = 49/242 (20%), Positives = 93/242 (38%), Gaps = 27/242 (11%)
Query: 76 EPMLSHTVRKHLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQ 135
E + + R+ LE L +E E + LQ ++E LK+ ++ D L
Sbjct: 511 EKLQTQLEREKQSNQDLETLSEELIREKEQLQSDMETLKADKARQIKDLEQEKDHLNRAM 570
Query: 136 GNQNEDKHLVTD-------NPSKINPETVAEWKKKL-------RTANEIYEKVKDD---V 178
+ E + ++ +K +TV E KL R + E+ K+
Sbjct: 571 WSLRERSQVSSEARMKDVEKENKALHQTVTEANGKLSQLEFEKRQLHRDLEQAKEKGERA 630
Query: 179 DKLKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKK 238
+KL+ ++L+ ENG L R+ L+ + V AL+ + + + E L+K
Sbjct: 631 EKLERELQRLQEENGRLARKVTSLETATEK----------VEALEHESQGLQLENRTLRK 680
Query: 239 ALERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSA 298
+L+ +LE K E + + +T K ++ E+ + + +
Sbjct: 681 SLDTLQNVSLQLEGLERDNKQLDAENLELRRLVETMRFTSTKLAQMERENQQLEREKEEL 740
Query: 299 RK 300
RK
Sbjct: 741 RK 742
Score = 31.6 bits (70), Expect = 2.7
Identities = 40/210 (19%), Positives = 86/210 (40%), Gaps = 31/210 (14%)
Query: 87 LRKTRLELLH-KEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLV 145
+ + LEL KE ++D + +EEL+ N+ L + + LT + ++ L
Sbjct: 325 VERLELELTRCKEKLHDVDFYKARMEELREDNIILIETKAMLEEQLTAARARGDKVHELE 384
Query: 146 TDN---PSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRL 202
+N SK++ + K R + E + ++ + + N+ L G E L
Sbjct: 385 KENLQLKSKLHDLELDRDTDKKRIEELLEENMVLEIAQKQSMNESAHL---GWELEQLSK 441
Query: 203 KAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALE--------------------- 241
A++ + S + F S++ + E+E L+ ++
Sbjct: 442 NADLSDASRKSFVFELNECASSRILKLEKENQSLQSTIQGLRDASLVLEESGLKCGELEK 501
Query: 242 ---RSDKYIEELESQVAQLKNSSEEKEAMN 268
+ K IE+L++Q+ + K S+++ E ++
Sbjct: 502 ENHQLSKKIEKLQTQLEREKQSNQDLETLS 531
Score = 30.0 bits (66), Expect = 7.9
Identities = 54/225 (24%), Positives = 97/225 (43%), Gaps = 30/225 (13%)
Query: 88 RKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTD 147
+ RLEL ++ E LQ+ +E K +LES++ + + E + L D
Sbjct: 753 KSERLELSYQSVSAENLRLQQSLESSSHKTQTLESELGEL----------EAERQALRRD 802
Query: 148 NPSKINPETVAEWKKKLRTA--NEIYEKVKDDVDKLKEANK---KLKLENGGLVRENLRL 202
+ E +K R A E+ + KD KEA + +++L++ L +L
Sbjct: 803 LEALRLANAQLEGAEKDRKALEQEVAQLEKDKKLLEKEAKRLWQQVELKDAVLDDSTAKL 862
Query: 203 KA-EVDNRSPQK-FGRFAVAALQSKVEQYERETNRLKKALE---------RSDKYIEELE 251
A E ++R+ K R AA K+++ E++ L K + R D +E+L+
Sbjct: 863 SAVEKESRALDKELARCRDAA--GKLKELEKDNRDLTKQVTVHARTLTTLREDLVLEKLK 920
Query: 252 SQ--VAQLKNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQ 294
SQ ++L S+E E + + L D GS + + +N+
Sbjct: 921 SQQLSSELDKLSQELEKVGLNRELLLQEDDSGSDTKYKILEGRNE 965
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 46.6 bits (109), Expect = 8e-05
Identities = 46/199 (23%), Positives = 87/199 (43%), Gaps = 25/199 (12%)
Query: 89 KTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTDN 148
K L + +Y ++ LQK++EE + L L Q+K Q N ++ + +
Sbjct: 135 KNELMAVRSKYSEDKANLQKQLEEAMNTQLELSEQLK--------FQNNSEDNVKKLQEE 186
Query: 149 PSKINP---ETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLEN-GGLVRENLRLKA 204
KI P E + +K+L + ++ + + EAN + +N L E L+LKA
Sbjct: 187 IEKIRPGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKA 246
Query: 205 EVDNRSPQKFGRFAVAALQSKVEQYERETNRLK-------KALERSDKYIE-ELESQVAQ 256
Q+ + + +++ +++E E N+L K E S+K I+ + E ++
Sbjct: 247 -----IHQEEVKELMCQIEASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECELEN 301
Query: 257 LKNSSEEKEAMNSICQTAL 275
L+ ++ N IC L
Sbjct: 302 LRKATSNANQDNQICSILL 320
Score = 43.9 bits (102), Expect = 5e-04
Identities = 50/231 (21%), Positives = 113/231 (48%), Gaps = 18/231 (7%)
Query: 87 LRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDK-HLV 145
L+K +++ +E ED + + +EL+ +++ +I+ + + L V+ +EDK +L
Sbjct: 95 LKKENIKM-KQEVEDSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYSEDKANLQ 153
Query: 146 TDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRLKAE 205
+N T E ++L+ N +D+V KL+E +K++ G + L L+ +
Sbjct: 154 KQLEEAMN--TQLELSEQLKFQN----NSEDNVKKLQEEIEKIR---PGFEEQILYLQKQ 204
Query: 206 VDNRSPQKFGRFAVAALQSKVE----QYERETNRL-KKALERSDKYIEELESQVAQLKNS 260
+D + +K + V LQ+ +E Y++ N L ++ L+ + EE++ + Q++ S
Sbjct: 205 LDATTDEK--KETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIEAS 262
Query: 261 SEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARKQPGSSTSSSSH 311
++E EA + K + SE+++ K + + + +S ++ +
Sbjct: 263 AKEHEAEINKLNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQDN 313
Score = 43.5 bits (101), Expect = 7e-04
Identities = 50/223 (22%), Positives = 104/223 (46%), Gaps = 23/223 (10%)
Query: 92 LELLHKEYEDEIDCLQKEVEELKSKNLS----LESQIKT-------ILDPLTLVQGNQNE 140
+E+L E + + +E E +K + S L+ +++T +L+ + +QG +
Sbjct: 487 MEILQTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEK 546
Query: 141 ---DKHLVTD--NPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKL--KLENG 193
+ LV + N K E + L + + ++++ ++ L E KL+N
Sbjct: 547 LLSQQELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNS 606
Query: 194 GLVRENLRLKAEVDNRSPQKFGRFAVAALQ--SKVEQYERE-TNRLKKALERSDKYIEEL 250
+N K E + R + G+ +Q S++EQ E T L++ L+ D+ ++L
Sbjct: 607 HEEMDNFHKKCEREERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKL 666
Query: 251 ESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKN 293
E + Q+K SE+KE +++ ++ + K S SE+ +S++
Sbjct: 667 EKLMVQMKVLSEDKEVLSAEVKSLYEENNKLS--SEKKQLSRD 707
Score = 43.5 bits (101), Expect = 7e-04
Identities = 54/228 (23%), Positives = 99/228 (43%), Gaps = 43/228 (18%)
Query: 85 KHLRKTRL--ELLHKEYEDEIDCLQKEVEELKSKNLSLESQI------KTILDPLTLVQG 136
+ LR + L E ++ + ED L +E L+S LE QI K ++D +
Sbjct: 1052 RQLRNSTLQCETINSDNED----LLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEK 1107
Query: 137 NQNEDK---HLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDK------------- 180
Q E K H T N + + + KK+L+ + E VK D +
Sbjct: 1108 LQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYER 1167
Query: 181 -LKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKA 239
+KE N+KL +N + E+L + ++ + + + +LQS V+QYE + ++K+
Sbjct: 1168 LMKELNQKLTNKNNKI--EDLEQEIKIQKQKQETLQE-EITSLQSSVQQYEEKNTKIKQL 1224
Query: 240 LERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEE 287
L ++ K + + S++ E + I Q +L + + S+ E
Sbjct: 1225 LVKTKKELAD-----------SKQAETDHLILQASLKGELEASQQQVE 1261
Score = 43.1 bits (100), Expect = 0.001
Identities = 53/224 (23%), Positives = 104/224 (46%), Gaps = 22/224 (9%)
Query: 66 KEIIGGTSESEPMLSHTV--RKHLRKTRLE---LLHKEYEDEIDCLQKEVEELKSKNLSL 120
KE+ SE E + S + + KTRLE LL + E C + E+ K K
Sbjct: 845 KELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHNEKEKCFIK 904
Query: 121 ESQ-IKTILDPLTLVQGNQNEDKHLVTDN----PSKINP--ETVAEWKKKLRTANEIYEK 173
E + +K +L+ L ++ + L+ D+ PS N +V E ++K+ + ++
Sbjct: 905 EHENLKPLLEQKEL--RDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKE 962
Query: 174 VKDDVDKLKEANKKLKLENGGLVRENLRLKAEVDNRSPQKFGRFA--------VAALQSK 225
++ ++K+K K K E +E +K E+++ +K A + ++
Sbjct: 963 KEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNL 1022
Query: 226 VEQYERETNRLKKALERSDKYIEELESQVAQLKNSSEEKEAMNS 269
+ +YE+++ +L ER++ + +E QL+NS+ + E +NS
Sbjct: 1023 LLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINS 1066
Score = 41.6 bits (96), Expect = 0.003
Identities = 59/243 (24%), Positives = 99/243 (40%), Gaps = 56/243 (23%)
Query: 98 EYEDEIDCLQKE----VEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTDNPSKIN 153
E E EI CLQ+E EELKS E + K +L
Sbjct: 810 ELEKEIKCLQEESVVQCEELKSLLRDYEQE-KVLL------------------------- 843
Query: 154 PETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRL-----KAEVDN 208
+K+L E ++ D+ ++K AN+K +LEN L+ + + K+E+ N
Sbjct: 844 -------RKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHN 896
Query: 209 RSPQKFGRFAVAALQSKVEQYERETNR-----LKKALERSDKY-------IEELESQVAQ 256
+ F + L+ +EQ E R LK +L +S ++ELE ++
Sbjct: 897 EKEKCFIK-EHENLKPLLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIEN 955
Query: 257 L-KNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARKQPGSSTSSSSHLAKP 315
L K E++E +N I A+ A + +E K + +S R + ++S L +
Sbjct: 956 LEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQG 1015
Query: 316 SSS 318
+ S
Sbjct: 1016 AES 1018
Score = 40.0 bits (92), Expect = 0.008
Identities = 54/238 (22%), Positives = 96/238 (40%), Gaps = 35/238 (14%)
Query: 62 ENPCKEIIGGTSESEPMLSHTVRKHLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLE 121
E E+ GG E+ L + + +L + K ++ + L EV+ L +N L
Sbjct: 642 EQKVNELTGGLEET---LKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLS 698
Query: 122 SQIKTILDPLTLVQGNQNEDK-------------HLVTDNPSKINPETVAEWKKKLRTAN 168
S+ K + L + +Q ED L+ + +N E +KL
Sbjct: 699 SEKKQLSRDLEVFL-SQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVKT 757
Query: 169 EIY-------------EKVKDDVDKLK---EANKKLKLENGGLV--RENLRLKAEVDNRS 210
++Y + KD V+ L+ E+ K+ E L R+ L+ E + +
Sbjct: 758 QLYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLAKINEEKCNLAFQRDEKVLELEKEIKC 817
Query: 211 PQKFGRFAVAALQSKVEQYERETNRLKKALERSDKYIEELESQVAQLKNSSEEKEAMN 268
Q+ L+S + YE+E L+K LE E L+S + ++KN++E+ N
Sbjct: 818 LQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLEN 875
Score = 33.5 bits (75), Expect = 0.71
Identities = 59/287 (20%), Positives = 120/287 (41%), Gaps = 52/287 (18%)
Query: 71 GTSESEPMLSHTVRKHLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLS--LESQIKTIL 128
G S+ E + + K +K + L ++ + L+KE+EEL+SK ++ IK +
Sbjct: 18 GKSKLETLPKEDLIKFAKKQMM--LIQKAKSRCTELEKEIEELRSKPVTEGTGDIIKALT 75
Query: 129 DPL--TLVQGNQNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANK 186
+ L L++ + E + L + E + ++ ++V+D V K+ +A+K
Sbjct: 76 ERLDALLLEKAETEQQCL------SLKKENI-----------KMKQEVEDSVTKMGDAHK 118
Query: 187 KLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSDKY 246
+L+ + V+E LK E + A++SK Y + L+K LE +
Sbjct: 119 ELEQSHINYVKEIENLKNE-------------LMAVRSK---YSEDKANLQKQLEEAMNT 162
Query: 247 IEELESQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARKQPGSST 306
EL Q+ NS + + + + K G EE ++ +KQ ++T
Sbjct: 163 QLELSEQLKFQNNSEDNVKKLQEEIE-------KIRPGFEEQIL------YLQKQLDATT 209
Query: 307 SSSSHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVML 353
+ + S Q++ + + K ++QE+V+ ++
Sbjct: 210 DEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELM 256
Score = 32.0 bits (71), Expect = 2.1
Identities = 113/633 (17%), Positives = 220/633 (34%), Gaps = 96/633 (15%)
Query: 58 PITPENPCKEIIGGTSESEPMLSHTVRKHLRKTRLELLHKEYEDEIDCLQKEVEELKSKN 117
P +P + + E + K + +++L+ + + E+D +KE + +K +
Sbjct: 936 PSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEEL 995
Query: 118 LSLESQ-----------------IKTIL-------DPLTLVQGNQNEDKHLVTDNPSKIN 153
SL S+ K +L + L + + N +H + D ++
Sbjct: 996 ESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLR 1055
Query: 154 P-------------------ETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLK----L 190
ET+ K L ++ K VDK EA K K
Sbjct: 1056 NSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIK 1115
Query: 191 ENGGLVRENLRLKAEVDNRSPQ-----------KFGRFAVAALQSKVEQYERETNRLKKA 239
E+ V E L+ ++ Q K + ++ YER L +
Sbjct: 1116 EHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQK 1175
Query: 240 LERSDKYIEELESQVAQLKNSSEE-KEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSA 298
L + IE+LE ++ K E +E + S+ + + K +K + V +K
Sbjct: 1176 LTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTK------ 1229
Query: 299 RKQPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKADL-NCSKNKDLYQEQVEVMLDVTD 357
++ S + + HL +S + +S +Q K L + K E ++ +
Sbjct: 1230 KELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQ 1289
Query: 358 TSMDTYLEREWGNKPSDCVPYKDEELYDLPAPCTPLSLSCLQLSTPENRESSVVQAGGSK 417
++ Y +R + +C K E+ + L +N+ S + G+K
Sbjct: 1290 RTLSAYQQRVTALQ-EECRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGAK 1348
Query: 418 KHSNHLRKLVFD---DFCDSSN--------VSNKDSSEDDISRSENEKKSECFSSPKTGF 466
+ HL L+ DS N + S D + N+ E S
Sbjct: 1349 QEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLERHNKMLQETVSKEAELR 1408
Query: 467 WDCCS---------TSYAQNLDFESSEGNTIANSVGEISSKLSE---KSGLCLSKRLNSI 514
CS + + Q + +S+ + NS + L E K+ L ++L+ +
Sbjct: 1409 EKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEEHRKTVETLQQQLSKM 1468
Query: 515 RS--FEMNR---TRTSSEASMDAAYLDKISELDSMMSESDNSKSPCNNGFKSLDLDGLSK 569
+ F++ TR+ + L + D + + G ++ D + +S
Sbjct: 1469 EAQLFQLKNEPTTRSPVSSQQSLKNLRERRNTDLPLLDMHTVTREEGEGMETTDTESVSS 1528
Query: 570 SSQGSEFLEE-PDKLEEKTELNLSKGSLTNDQL 601
+S ++ LE+ + E K E L T ++L
Sbjct: 1529 ASTYTQSLEQLLNSPETKLEPPLWHAEFTKEEL 1561
>gi|110347443 TATA element modulatory factor 1 [Homo sapiens]
Length = 1093
Score = 46.6 bits (109), Expect = 8e-05
Identities = 60/297 (20%), Positives = 128/297 (43%), Gaps = 37/297 (12%)
Query: 66 KEIIGGTSESEPMLSHTVRKHLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIK 125
K+++ G E E ++K L + + E ++ LQ +++EL+ KN S+++ +
Sbjct: 608 KQVLDGKEEVEKQHRENIKK------LNSMVERQEKDLGRLQVDMDELEEKNRSIQAALD 661
Query: 126 TILDPLTLVQGNQNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEAN 185
+ LT D H N +K + A ++++ E+ ++ ++ ++
Sbjct: 662 SAYKELT--------DLHKA--NAAKDSEAQEAALSREMKAKEELSAALEKAQEEARQQQ 711
Query: 186 KKLKLENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSD- 244
+ L ++ G L R L+ + R + + R + LQ ++++ E L +++ +
Sbjct: 712 ETLAIQVGDL-RLALQRTEQAAARK-EDYLRHEIGELQQRLQEAENRNQELSQSVSSTTR 769
Query: 245 ---KYIEELESQVAQLKNSSEEKEAMNS----ICQTALSADGKGSKGSEEDVVSKNQGDS 297
+ IE L++ + +S E+ E S QT L+A + + + E+++
Sbjct: 770 PLLRQIENLQATLGSQTSSWEKLEKNLSDRLGESQTLLAAAVERERAATEELL------- 822
Query: 298 ARKQPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLD 354
A K SS S + L + +SR A+ ES + YQ ++E + D
Sbjct: 823 ANKIQMSSMESQNSLLRQENSRF----QAQLESEKNRLCKLEDENNRYQVELENLKD 875
Score = 35.4 bits (80), Expect = 0.19
Identities = 47/240 (19%), Positives = 93/240 (38%), Gaps = 28/240 (11%)
Query: 83 VRKHLRKTRLELLHKE--YEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNE 140
+R L++T KE EI LQ+ ++E +++N L + + PL N
Sbjct: 721 LRLALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELSQSVSSTTRPLLRQIENLQA 780
Query: 141 DKHLVTDNPSKINP---ETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVR 197
T + K+ + + E + L A E +++ K ++ +N L +
Sbjct: 781 TLGSQTSSWEKLEKNLSDRLGESQTLLAAAVERERAATEELLANKIQMSSMESQNSLLRQ 840
Query: 198 ENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSDKYIEELESQVAQL 257
EN R +A Q E E NRL K + +++Y ELE+ +
Sbjct: 841 ENSRFQA-----------------------QLESEKNRLCKLEDENNRYQVELENLKDEY 877
Query: 258 KNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARKQPGSSTSSSSHLAKPSS 317
+ EE ++ + L + + + + + +++ S SS+ +++ SS
Sbjct: 878 VRTLEETRKEKTLLNSQLEMERMKVEQERKKAIFTQETIKEKERKPFSVSSTPTMSRSSS 937
Score = 33.9 bits (76), Expect = 0.55
Identities = 35/162 (21%), Positives = 69/162 (42%), Gaps = 9/162 (5%)
Query: 135 QGNQNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKV-KDDVDKLKEANKKLKLENG 193
+G DK P++ PE ++E + +T + EK+ K + L + +K LE
Sbjct: 419 EGQTVLDKVAEQCEPAESQPEALSEKEDVCKTVEFLNEKLEKREAQLLSLSKEKALLEEA 478
Query: 194 --GLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSDKYIEELE 251
L E R+K E + S K ++ + E++ K + + K I+ ++
Sbjct: 479 FDNLKDEMFRVKEESSSISSLK------DEFTQRIAEAEKKVQLACKERDAAKKEIKNIK 532
Query: 252 SQVAQLKNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKN 293
++A NSSE + + + +G K S++ + + N
Sbjct: 533 EELATRLNSSETADLLKEKDEQIRGLMEEGEKLSKQQLHNSN 574
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 46.6 bits (109), Expect = 8e-05
Identities = 61/285 (21%), Positives = 127/285 (44%), Gaps = 28/285 (9%)
Query: 89 KTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHL---V 145
K +LE E++ EID L +E + +LE +T+ D L+ +G E + +
Sbjct: 1215 KQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSEL 1274
Query: 146 TDNPSKINPET-------------VAEWKKKLRTANEIYEKVKDDVDKLKEANKKL--KL 190
T S++ E V++ + + + E++K +++ +A L L
Sbjct: 1275 TTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHAL 1334
Query: 191 ENGGLVRENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSDKYIEEL 250
++ + LR + E + + R A++ S+V Q+ T A++R+++ +EE
Sbjct: 1335 QSSRHDCDLLREQYEEEQEGKAELQR-ALSKANSEVAQW--RTKYETDAIQRTEE-LEEA 1390
Query: 251 ESQVAQ-LKNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARKQPGSSTSSS 309
+ ++AQ L++S E+ EA+N+ C +L + +G ED++ + ++ +
Sbjct: 1391 KKKLAQRLQDSEEQVEAVNAKC-ASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRN 1449
Query: 310 SHLAKPSSSRLCDTSSARQESTSKADLNCS----KNKDLYQEQVE 350
C+ S A E++ K + S K K+ Y+E ++
Sbjct: 1450 FDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALD 1494
Score = 44.7 bits (104), Expect = 3e-04
Identities = 69/324 (21%), Positives = 127/324 (39%), Gaps = 56/324 (17%)
Query: 89 KTRLELLHKEYEDEIDCLQKEVEELKSKNLSLE---SQIKTILDPLTLVQGNQNEDKHLV 145
K +LE KE + + ++ EL +K LE S++K +D L L ++KH
Sbjct: 913 KFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHAT 972
Query: 146 TDNPSKINPE------TVAEWKKKLRTANEIYEKVKDDV----DKLKEANK-KLKLE--- 191
+ + E T+A+ ++ + E +++ DD+ DK+ NK K KLE
Sbjct: 973 ENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQV 1032
Query: 192 -------------------NGGLVRENLRL-----------KAEVDNRSPQKFGRFAVAA 221
N + +L+L K ++D R +K F
Sbjct: 1033 EDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKK--DFEYCQ 1090
Query: 222 LQSKVEQYERETNRLKKALERSDKYIEELESQVAQLKNSSEEKEAMNSICQTALS----- 276
LQSKVE + + +K ++ IEELE ++ + + + E S L
Sbjct: 1091 LQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSER 1150
Query: 277 -ADGKGSKGSEEDVVSKNQGDSARKQPGSSTSSSSHLAKPSSSRLCDTSSARQESTSKAD 335
+ G ++ ++ K + + + + ++ H A ++ R S + +
Sbjct: 1151 LEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDN 1210
Query: 336 LNCSKNKDLYQEQVEVMLDVTDTS 359
L K K L +E+ E L++ D S
Sbjct: 1211 LQRVKQK-LEKEKSEFKLEIDDLS 1233
Score = 37.0 bits (84), Expect = 0.065
Identities = 54/245 (22%), Positives = 93/245 (37%), Gaps = 41/245 (16%)
Query: 88 RKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLT--LVQGNQNEDKHLV 145
R LE K+ + +++VE + +K SLE + + + +V +
Sbjct: 1383 RTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAA 1442
Query: 146 TDNPSKINPETVAEWKKKLRTAN---------------------EIYEKVKDDVDKLKEA 184
D + + +AEWK K + YE+ D ++ +K
Sbjct: 1443 LDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRE 1502
Query: 185 NKKLK----------LENGGLVR--ENLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERE 232
NK L+ ENG + E R + E++ Q A AAL+ + + R
Sbjct: 1503 NKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRI 1562
Query: 233 TNRLKKALERSDKYIEELESQVAQLK-NSSEEKEAMNSICQTALSADGKGSKGSEEDVVS 291
L + D+ I E + ++ QLK N E M Q+AL A+ + S+ +
Sbjct: 1563 QLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETM----QSALDAEVR-SRNEAIRLKK 1617
Query: 292 KNQGD 296
K +GD
Sbjct: 1618 KMEGD 1622
Score = 35.4 bits (80), Expect = 0.19
Identities = 48/250 (19%), Positives = 107/250 (42%), Gaps = 12/250 (4%)
Query: 89 KTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTDN 148
K +L+ K+ + E LQ +VE+ ++ L + +IK + + + ++ + +
Sbjct: 1074 KQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARI------EELEEEIEAER 1127
Query: 149 PSKINPETV-AEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVR--ENLRLKAE 205
++ E +++ ++L +E E+ E NKK + E L R E L+ E
Sbjct: 1128 ATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHE 1187
Query: 206 VDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSDKYIEELESQVAQLKNSSEEKE 265
+ +K +VA L +++ +R +L+K I++L S +++ S+ K
Sbjct: 1188 AMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSS---MESVSKSKA 1244
Query: 266 AMNSICQTALSADGKGSKGSEEDVVSKNQGDSARKQPGSSTSSSSHLAKPSSSRLCDTSS 325
+ IC+T + +EE S ++ + + + + S + S + S
Sbjct: 1245 NLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSR 1304
Query: 326 ARQESTSKAD 335
++Q T + +
Sbjct: 1305 SKQAFTQQTE 1314
>gi|190194355 p90 autoantigen [Homo sapiens]
Length = 905
Score = 46.2 bits (108), Expect = 1e-04
Identities = 59/219 (26%), Positives = 101/219 (46%), Gaps = 35/219 (15%)
Query: 79 LSHTVRKHLRKTR-LELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKT--ILDP--LTL 133
L+ +R+ RK L +L K + E + Q ++E L N LES + IL + L
Sbjct: 675 LASMLREVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMEL 734
Query: 134 VQGNQ-----NEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKL 188
+Q N+ N+D + D+ +K ETV + + L+ NE K +++ ++
Sbjct: 735 LQRNESTEKKNKDLQITCDSLNK-QIETVKKLNESLKEQNE-----KSIAQLIEKEEQRK 788
Query: 189 KLENGGLVRE----NLRLKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSD 244
+++N + RE NL K +V + LQ + E E + L+K L R++
Sbjct: 789 EVQNQLVDREHKLANLHQKTKVQEEK--------IKTLQKEREDKEETIDILRKELSRTE 840
Query: 245 KYIEEL-------ESQVAQLKNSSEEKEAMNSICQTALS 276
+ +EL E Q AQL+ EEKE++ + Q L+
Sbjct: 841 QIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEELN 879
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 46.2 bits (108), Expect = 1e-04
Identities = 61/280 (21%), Positives = 117/280 (41%), Gaps = 27/280 (9%)
Query: 97 KEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQN-----EDKHLVTDNPSK 151
KE E ++ L++ + K +NL LE++ + L L Q Q + K ++ ++
Sbjct: 734 KEMEKKL--LEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRN 791
Query: 152 INPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRLK---AEVDN 208
+ + E +K+ T N++ + + V+ LK + K+LK EN L+ + L+ AE+
Sbjct: 792 LTLKIEQETQKRCLTQNDLKMQTQQ-VNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRK 850
Query: 209 RSPQKFGRFAVAALQSKVEQY-----ERETNRLKKALERSDKYIEELESQVAQLKNSSEE 263
G+ Q + EQY + + LK+ E K +EL+ + +L++ +
Sbjct: 851 ERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDS 910
Query: 264 KEAMNSICQTALSADGKGSKGSEEDVVSKNQ---------GDSARKQPGSSTSSSSHLAK 314
A I T ++ +EE + + + T + +A
Sbjct: 911 LAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIAS 970
Query: 315 PSSSRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLD 354
+ TS + K +LN +K KD+ QEQ+ + D
Sbjct: 971 LEETNRTLTSDVANLANEKEELN-NKLKDV-QEQLSRLKD 1008
Score = 39.3 bits (90), Expect = 0.013
Identities = 49/215 (22%), Positives = 101/215 (46%), Gaps = 26/215 (12%)
Query: 91 RLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTDNPS 150
+L L + +E+ ++ ++ KS N LE K + + +TL + ++ + L +
Sbjct: 448 KLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEEEITLRKSVESALRQL--EREK 505
Query: 151 KINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGGLVRENLRLKAEVDNRS 210
+ AE+++K + +++DV+ LK+ + LK N +N ++ E N+
Sbjct: 506 ALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRN-----QNSQISTEKVNQL 560
Query: 211 PQKFGRFAVAALQSKVEQYERETNRLKKALERSDKYIEELESQVAQLKNSS--------- 261
++ A L+++ + RL+K S K I++LES L++ +
Sbjct: 561 QRQLDE-TNALLRTESDT----AARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLK 615
Query: 262 EEKEAMNSICQTALSADGKG-SKGSEEDVVSKNQG 295
EKE +N Q+AL ++ + + GSE +++ QG
Sbjct: 616 LEKEFIN--LQSALESERRDRTHGSE--IINDLQG 646
Score = 35.4 bits (80), Expect = 0.19
Identities = 65/295 (22%), Positives = 123/295 (41%), Gaps = 57/295 (19%)
Query: 91 RLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDKHLVTDNPS 150
++EL ++ ++ L+KE ++ + + Q+K I L Q E +H T
Sbjct: 664 KVELEKRQLQERFTDLEKEKSNME---IDMTYQLKVIQQSL-----EQEEAEHKAT---- 711
Query: 151 KINPETVAEWKKKLRTANEIYEKVKD-DVDKLKEANKKLKLENGGLVR--ENLRLKAEVD 207
K +L N+IYE +++ + +KE KKL LE L + ENL L+AE
Sbjct: 712 ----------KARLADKNKIYESIEEAKSEAMKEMEKKL-LEERTLKQKVENLLLEAEKR 760
Query: 208 --------NRSPQKFGRFA---------VAALQSKVEQYERETNRLKKALERSDKYIEEL 250
+S QK V L K+EQ ET K+ L ++D ++
Sbjct: 761 CSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQ---ETQ--KRCLTQND--LKMQ 813
Query: 251 ESQVAQLKNSSEE-KEAMNSICQTALSADGKGSKGSEEDVVSKNQGDSARKQPGSSTSSS 309
QV LK S ++ K+ N + + ++ + + ++ +E + D K+ +
Sbjct: 814 TQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKE----RQDADGQMKELQDQLEAE 869
Query: 310 SHLAKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQEQ--VEVMLDVTDTSMDT 362
+ + +++ + +E T K ++L E+ + L++T T D+
Sbjct: 870 QYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADS 924
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
domain 1 [Homo sapiens]
Length = 1412
Score = 45.8 bits (107), Expect = 1e-04
Identities = 49/202 (24%), Positives = 96/202 (47%), Gaps = 14/202 (6%)
Query: 73 SESEPMLSHTVRKHLRKTRLELLHKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLT 132
+E +S T + + + +++ID QKE++ LKS+ +L+ +L T
Sbjct: 262 AELSQKVSETTTSRQNEKEISQKCQVLDEDIDAKQKEIQSLKSQISALQKGYSKVLCQ-T 320
Query: 133 LVQGN------QNEDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANK 186
L + N +NE ++L DN I V+ +K + +E +++K++V LK NK
Sbjct: 321 LSERNSEITSLKNEGENLKRDN--AITSGMVSSLQKDILAKDEQVQQLKEEVSHLKSQNK 378
Query: 187 KL--KLENGGLVRENLR--LKAEVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALER 242
+LE G L+ LK E +R ++ + +++++ E+E +L+ L +
Sbjct: 379 DKDHQLEALGSRCSVLKEELKQEDAHRELREAQEKELKLCKTQIQDMEKEMKKLRAELRK 438
Query: 243 SDKYIEELESQVAQLKNSSEEK 264
S + + S+ + K+ EEK
Sbjct: 439 SCTE-QSVISRTLREKSKVEEK 459
Score = 34.7 bits (78), Expect = 0.32
Identities = 40/233 (17%), Positives = 92/233 (39%), Gaps = 26/233 (11%)
Query: 140 EDKHLVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLEN----GGL 195
E++ + + S + + A K + N + E ++++ +++E ++L + +
Sbjct: 707 EERKRMQELESLLAQQKKALAKSITQEKNRVKEALEEEQTRVQELEERLARQKEVLESSI 766
Query: 196 VRENLRLKA--EVDNRSPQKFGRFAVAALQSKVEQYERETNRLKKALERSDKYIEELESQ 253
E + K E + R Q + E + K+A+E+ K +++LE++
Sbjct: 767 AHEKRKAKEALESEKRKVQDLENHLTQQKEISESNIAYEKRKAKEAMEKEKKKVQDLENR 826
Query: 254 VAQLKNSSEEKEAMNSICQTALSADGKGSKGSEEDVVSKNQGDS-ARKQPGSSTSSSSHL 312
+ + K E KE +EDV++ D+ A + T ++ L
Sbjct: 827 LTKQKEELELKE-------------------QKEDVLNNKLSDALAMVEETQKTKATESL 867
Query: 313 AKPSSSRLCDTSSARQESTSKADLNCSKNKDLYQEQVEVMLDVTDTSMDTYLE 365
S + + + A E+T + + L Q+ V+ + D ++ + E
Sbjct: 868 KAESLALKLNETLAELETTKTKMIMVEERLILQQKMVKALQDEQESQRHGFEE 920
Score = 34.3 bits (77), Expect = 0.42
Identities = 41/191 (21%), Positives = 79/191 (41%), Gaps = 13/191 (6%)
Query: 86 HLRKTRLELL-HKEYEDEIDCLQKEVEELKSKNLSLESQIKTILDPLTLVQGNQNEDK-H 143
H K ++LL H + + LQK V ++ LS +++ +L L ++ + N+D+
Sbjct: 580 HDLKKEVDLLQHLQVSPPVSGLQKVVLDVLRHALSWLEEVEQLLRDLGILPSSPNKDQVQ 639
Query: 144 LVTDNPSKINPETVAEWKKKLRTANEIYEKVKDDVDKLKEANKKLKLENGG------LVR 197
+ N + A + A + + + +A GG + +
Sbjct: 640 QFSGNSAVFTAGKAAGASGREGEAERGEARARGEAQSQNQATDG---REGGKALEEYITQ 696
Query: 198 ENLRLKAEVDNRSPQKFGRFAVAALQSKV--EQYERETNRLKKALERSDKYIEELESQVA 255
E R K ++ + ++ A Q K + +E NR+K+ALE ++ELE ++A
Sbjct: 697 ERNRAKETLEEERKRMQELESLLAQQKKALAKSITQEKNRVKEALEEEQTRVQELEERLA 756
Query: 256 QLKNSSEEKEA 266
+ K E A
Sbjct: 757 RQKEVLESSIA 767
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.124 0.346
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,426,726
Number of Sequences: 37866
Number of extensions: 1272561
Number of successful extensions: 8698
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 164
Number of HSP's successfully gapped in prelim test: 744
Number of HSP's that attempted gapping in prelim test: 6428
Number of HSP's gapped (non-prelim): 2410
length of query: 726
length of database: 18,247,518
effective HSP length: 110
effective length of query: 616
effective length of database: 14,082,258
effective search space: 8674670928
effective search space used: 8674670928
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.