BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|88703045 proline rich 11 [Homo sapiens] (360 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|88703045 proline rich 11 [Homo sapiens] 735 0.0 gi|150170670 piccolo isoform 2 [Homo sapiens] 59 5e-09 gi|150378539 piccolo isoform 1 [Homo sapiens] 59 5e-09 gi|47132519 Ras association and pleckstrin homology domains 1 is... 57 3e-08 gi|52485606 formin-like 2 [Homo sapiens] 53 5e-07 gi|187761324 shootin1 isoform a [Homo sapiens] 53 5e-07 gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 52 8e-07 gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 52 1e-06 gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 52 1e-06 gi|195947369 junction-mediating and regulatory protein [Homo sap... 52 1e-06 gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 51 1e-06 gi|153792074 proline rich 12 [Homo sapiens] 51 2e-06 gi|150378503 leiomodin 2 (cardiac) [Homo sapiens] 50 2e-06 gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 50 3e-06 gi|122937271 WAS protein homolog associated with actin, golgi me... 50 3e-06 gi|15812226 transcriptional regulating factor 1 [Homo sapiens] 50 3e-06 gi|119120861 formin-like 3 isoform 2 [Homo sapiens] 50 4e-06 gi|119120874 formin-like 3 isoform 1 [Homo sapiens] 50 4e-06 gi|56549694 enabled homolog isoform a [Homo sapiens] 49 9e-06 gi|39930375 enabled homolog isoform b [Homo sapiens] 49 9e-06 gi|116256475 zinc finger protein 827 [Homo sapiens] 48 1e-05 gi|6382071 diaphanous 2 isoform 12C [Homo sapiens] 48 1e-05 gi|5803003 diaphanous 2 isoform 156 [Homo sapiens] 48 1e-05 gi|210032580 SET domain containing 1B [Homo sapiens] 48 1e-05 gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3 [... 47 2e-05 gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1 [... 47 2e-05 gi|11386183 WAS protein family, member 2 [Homo sapiens] 47 2e-05 gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] 47 2e-05 gi|40807465 zinc finger protein 341 [Homo sapiens] 47 2e-05 gi|55741677 SET domain containing 1A [Homo sapiens] 47 3e-05 >gi|88703045 proline rich 11 [Homo sapiens] Length = 360 Score = 735 bits (1898), Expect = 0.0 Identities = 360/360 (100%), Positives = 360/360 (100%) Query: 1 MPKFKQRRRKLKAKAERLFKKKEASHFQSKLITPPPPPPSPERVGISSIDISQSRSWLTS 60 MPKFKQRRRKLKAKAERLFKKKEASHFQSKLITPPPPPPSPERVGISSIDISQSRSWLTS Sbjct: 1 MPKFKQRRRKLKAKAERLFKKKEASHFQSKLITPPPPPPSPERVGISSIDISQSRSWLTS 60 Query: 61 SWNFNFPNIRDAIKLWTNRVWSIYSWCQNCITQSLEVLKDTIFPSRICHRELYSVKQQFC 120 SWNFNFPNIRDAIKLWTNRVWSIYSWCQNCITQSLEVLKDTIFPSRICHRELYSVKQQFC Sbjct: 61 SWNFNFPNIRDAIKLWTNRVWSIYSWCQNCITQSLEVLKDTIFPSRICHRELYSVKQQFC 120 Query: 121 ILESKLCKLQEALKTISESSSCPSCGQTCHMSGKLTNVPACVLITPGDSKAVLPPTLPQP 180 ILESKLCKLQEALKTISESSSCPSCGQTCHMSGKLTNVPACVLITPGDSKAVLPPTLPQP Sbjct: 121 ILESKLCKLQEALKTISESSSCPSCGQTCHMSGKLTNVPACVLITPGDSKAVLPPTLPQP 180 Query: 181 ASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPLKKDGPMQITVKDLLTVKLKKT 240 ASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPLKKDGPMQITVKDLLTVKLKKT Sbjct: 181 ASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPLKKDGPMQITVKDLLTVKLKKT 240 Query: 241 QSLDEKRKLIPSPKARNPLVTVSDLQHVTLKPNSKVLSTRVTNVLITPGKSQMDLRKLLR 300 QSLDEKRKLIPSPKARNPLVTVSDLQHVTLKPNSKVLSTRVTNVLITPGKSQMDLRKLLR Sbjct: 241 QSLDEKRKLIPSPKARNPLVTVSDLQHVTLKPNSKVLSTRVTNVLITPGKSQMDLRKLLR 300 Query: 301 KVDVERSPGGTPLTNKENMETGTGLTPVMTQALRRKFQLAHPRSPTPTLPLSTSSFDEQN 360 KVDVERSPGGTPLTNKENMETGTGLTPVMTQALRRKFQLAHPRSPTPTLPLSTSSFDEQN Sbjct: 301 KVDVERSPGGTPLTNKENMETGTGLTPVMTQALRRKFQLAHPRSPTPTLPLSTSSFDEQN 360 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 59.3 bits (142), Expect = 5e-09 Identities = 56/186 (30%), Positives = 76/186 (40%), Gaps = 29/186 (15%) Query: 174 PPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKPSL---AKALQAGPLKKDGPMQITVK 230 PP P P PPPPPPPP PPPPPPL P KP++ K A P+ P+ V Sbjct: 2405 PPPPPPP----PPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVT 2460 Query: 231 DLLTVKLKKTQSLDEKRKLIPSPKARNPLVTVSDLQHVTLKPNSKVLSTRVTNVLITPGK 290 L T + ++ L R +P P KP+S + + L+ + Sbjct: 2461 TLETTAVLRSNGLPVTRICTTAPPPVPP------------KPSS------IPSGLVFTHR 2502 Query: 291 SQMDLRKLLRKVDVERSPGGTPL-TNKENMETGTGLTPVMTQALRRKFQLAHPRSPTPTL 349 + + K + + P T T+ TG LT MT L A + P+PT Sbjct: 2503 PEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNL---VTSADYKLPSPTS 2559 Query: 350 PLSTSS 355 PLS S Sbjct: 2560 PLSPHS 2565 Score = 33.9 bits (76), Expect = 0.23 Identities = 19/51 (37%), Positives = 22/51 (43%), Gaps = 4/51 (7%) Query: 174 PPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPLKKDGP 224 P LP PA PPP P P PPP P + PS P ++ GP Sbjct: 470 PSQLPGPAK----PPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGP 516 Score = 30.4 bits (67), Expect = 2.6 Identities = 39/131 (29%), Positives = 47/131 (35%), Gaps = 19/131 (14%) Query: 166 PGDSKAVLPPTLPQPASHFPPPPPPPPLPPPP-------PPLAPVLLRKPSLAKALQAGP 218 PG +K P QP S PPP P P P P PP KPS A Q P Sbjct: 494 PGSAK----PPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPS---AQQPSP 546 Query: 219 LKKDGPMQI-TVKDLLTVKLKKTQSLDEKRKLIPS---PKARNPLVTVSD-LQHVTLKPN 273 K V + K + ++ K PS PK PL ++ L HV K N Sbjct: 547 AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKAN 606 Query: 274 SKVLSTRVTNV 284 + T V Sbjct: 607 FNTCTECQTTV 617 Score = 30.0 bits (66), Expect = 3.4 Identities = 13/37 (35%), Positives = 15/37 (40%) Query: 166 PGDSKAVLPPTLPQPASHFPPPPPPPPLPPPPPPLAP 202 P + P QP + PP PP PP PL P Sbjct: 332 PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGP 368 Score = 28.9 bits (63), Expect = 7.5 Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 12/59 (20%) Query: 174 PPTLPQPASHFPP------PPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPLKKDGPMQ 226 PP + QP H P PP L P PP ++PS+ P+ D P Q Sbjct: 704 PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPP------KEPSVPSEQDKAPVADDKPKQ 756 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 59.3 bits (142), Expect = 5e-09 Identities = 56/186 (30%), Positives = 76/186 (40%), Gaps = 29/186 (15%) Query: 174 PPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKPSL---AKALQAGPLKKDGPMQITVK 230 PP P P PPPPPPPP PPPPPPL P KP++ K A P+ P+ V Sbjct: 2405 PPPPPPP----PPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVT 2460 Query: 231 DLLTVKLKKTQSLDEKRKLIPSPKARNPLVTVSDLQHVTLKPNSKVLSTRVTNVLITPGK 290 L T + ++ L R +P P KP+S + + L+ + Sbjct: 2461 TLETTAVLRSNGLPVTRICTTAPPPVPP------------KPSS------IPSGLVFTHR 2502 Query: 291 SQMDLRKLLRKVDVERSPGGTPL-TNKENMETGTGLTPVMTQALRRKFQLAHPRSPTPTL 349 + + K + + P T T+ TG LT MT L A + P+PT Sbjct: 2503 PEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNL---VTSADYKLPSPTS 2559 Query: 350 PLSTSS 355 PLS S Sbjct: 2560 PLSPHS 2565 Score = 33.9 bits (76), Expect = 0.23 Identities = 19/51 (37%), Positives = 22/51 (43%), Gaps = 4/51 (7%) Query: 174 PPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPLKKDGP 224 P LP PA PPP P P PPP P + PS P ++ GP Sbjct: 470 PSQLPGPAK----PPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGP 516 Score = 30.4 bits (67), Expect = 2.6 Identities = 39/131 (29%), Positives = 47/131 (35%), Gaps = 19/131 (14%) Query: 166 PGDSKAVLPPTLPQPASHFPPPPPPPPLPPPP-------PPLAPVLLRKPSLAKALQAGP 218 PG +K P QP S PPP P P P P PP KPS A Q P Sbjct: 494 PGSAK----PPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPS---AQQPSP 546 Query: 219 LKKDGPMQI-TVKDLLTVKLKKTQSLDEKRKLIPS---PKARNPLVTVSD-LQHVTLKPN 273 K V + K + ++ K PS PK PL ++ L HV K N Sbjct: 547 AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKAN 606 Query: 274 SKVLSTRVTNV 284 + T V Sbjct: 607 FNTCTECQTTV 617 Score = 30.0 bits (66), Expect = 3.4 Identities = 13/37 (35%), Positives = 15/37 (40%) Query: 166 PGDSKAVLPPTLPQPASHFPPPPPPPPLPPPPPPLAP 202 P + P QP + PP PP PP PL P Sbjct: 332 PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGP 368 Score = 28.9 bits (63), Expect = 7.5 Identities = 18/59 (30%), Positives = 23/59 (38%), Gaps = 12/59 (20%) Query: 174 PPTLPQPASHFPP------PPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPLKKDGPMQ 226 PP + QP H P PP L P PP ++PS+ P+ D P Q Sbjct: 704 PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPP------KEPSVPSEQDKAPVADDKPKQ 756 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 56.6 bits (135), Expect = 3e-08 Identities = 30/65 (46%), Positives = 33/65 (50%), Gaps = 2/65 (3%) Query: 157 NVPACVLITP--GDSKAVLPPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKAL 214 N P L+ P K V P T QP+ PPPPPPPP PPPPPP P L S A Sbjct: 599 NRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAG 658 Query: 215 QAGPL 219 A P+ Sbjct: 659 SAAPM 663 Score = 45.4 bits (106), Expect = 8e-05 Identities = 45/159 (28%), Positives = 65/159 (40%), Gaps = 22/159 (13%) Query: 174 PPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPLKKDGPMQITVKDLL 233 P ++P P+ FPPPPP L PPPP +PV P P K P + Sbjct: 906 PSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGK------- 958 Query: 234 TVKLKKTQSLDEKRKLIPSPKARNPLVTVSDLQHVTLK-PNSKVLSTRVTNVLITPGKSQ 292 K KT S K K P+P+ + + + S +H K P+ L ++ T P +S Sbjct: 959 --KTSKTSSPGGK-KPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFT----PPAESG 1011 Query: 293 MDLRKLLRKVDVERSPGGTPLTNKENMETGTGLTPVMTQ 331 ++ L P P K N+ +G L V+ Q Sbjct: 1012 SPSKETL------PPPAAPPKPGKLNL-SGVNLPGVLQQ 1043 Score = 40.8 bits (94), Expect = 0.002 Identities = 20/48 (41%), Positives = 23/48 (47%), Gaps = 3/48 (6%) Query: 156 TNVPACVLITPGDSKAVLPPTLPQPA---SHFPPPPPPPPLPPPPPPL 200 T P P +PP QPA S+ PP PP PP+P PPP L Sbjct: 793 TVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTL 840 Score = 40.0 bits (92), Expect = 0.003 Identities = 28/87 (32%), Positives = 34/87 (39%), Gaps = 11/87 (12%) Query: 139 SSSCPSCGQTCHMSGKLTNVPACVLITPGDSKAVLPPTLP-------QPASHFPP----P 187 S S PS G M K + + + PPT P +P PP P Sbjct: 651 SQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVP 710 Query: 188 PPPPPLPPPPPPLAPVLLRKPSLAKAL 214 PPPPP PPP P A L+ A +L Sbjct: 711 PPPPPPPPPTPGSAMAQLKPAPCAPSL 737 Score = 38.1 bits (87), Expect = 0.012 Identities = 23/59 (38%), Positives = 28/59 (47%), Gaps = 21/59 (35%) Query: 165 TPGDSKAVLPP-----TLPQPASHFPP----------------PPPPPPLPPPPPPLAP 202 TPG + A L P +LPQ ++ PP PPPPPP+P P PP AP Sbjct: 720 TPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAP 778 Score = 37.4 bits (85), Expect = 0.021 Identities = 19/43 (44%), Positives = 22/43 (51%), Gaps = 6/43 (13%) Query: 172 VLPPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKAL 214 V PPT P PPPP P PLPP PP V + P+ K + Sbjct: 758 VAPPTPP------PPPPIPAPLPPQAPPKPLVTIPAPTSTKTV 794 Score = 36.6 bits (83), Expect = 0.036 Identities = 16/37 (43%), Positives = 18/37 (48%) Query: 166 PGDSKAVLPPTLPQPASHFPPPPPPPPLPPPPPPLAP 202 P +S V PP P P PPPPPP P P +P Sbjct: 920 PPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSP 956 Score = 35.8 bits (81), Expect = 0.061 Identities = 21/53 (39%), Positives = 26/53 (49%), Gaps = 8/53 (15%) Query: 166 PGDSKAVLPPTLPQPASHFPPPPPPP-----PLPPPPPPLAPVLLRKPSLAKA 213 P + +P + Q AS FPPPP PP PL P P +AP + P KA Sbjct: 851 PPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAP---QSPPAVKA 900 Score = 33.9 bits (76), Expect = 0.23 Identities = 20/49 (40%), Positives = 23/49 (46%), Gaps = 13/49 (26%) Query: 172 VLPPTLPQPASHFPPPPPPPPLPP------------PPPPLAPVLLRKP 208 V PPTLP+ S F PPP PL P PPPP P + +P Sbjct: 835 VPPPTLPKQQS-FCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQP 882 Score = 32.0 bits (71), Expect = 0.88 Identities = 33/138 (23%), Positives = 48/138 (34%), Gaps = 13/138 (9%) Query: 128 KLQEALKTISESSSCPSCGQTCHMSGKLTNVPACVLITPGDSKAVLPPTLPQPASHFPPP 187 +L+E+ K ES + P +S P ++TP + PP P P PPP Sbjct: 586 QLEESSKARMESMNRPYTSLVPPLS------PQPKIVTPYTASQPSPPLPPPPPPPPPPP 639 Query: 188 PPP-------PPLPPPPPPLAPVLLRKPSLAKALQAGPLKKDGPMQITVKDLLTVKLKKT 240 PPP P P A + K S LQ + ++ + K Sbjct: 640 PPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKP 699 Query: 241 QSLDEKRKLIPSPKARNP 258 Q L ++P P P Sbjct: 700 QILVPPNGVVPPPPPPPP 717 Score = 32.0 bits (71), Expect = 0.88 Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 10/63 (15%) Query: 159 PACVLITPGDSKAVLPPTLPQPASHFPPPPPPPPLP---------PPPPPLAPVLLRKPS 209 P + P +K V P + Q A P PP PP PP PP PV + P+ Sbjct: 781 PLVTIPAPTSTKTVAP-VVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPT 839 Query: 210 LAK 212 L K Sbjct: 840 LPK 842 Score = 30.4 bits (67), Expect = 2.6 Identities = 21/64 (32%), Positives = 24/64 (37%), Gaps = 29/64 (45%) Query: 174 PPTLPQPAS---------------HFPPPPPP-------------PPLPPPPPPL-APVL 204 PP P P S F PPPP PP PPPPPP+ AP+ Sbjct: 715 PPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLP 774 Query: 205 LRKP 208 + P Sbjct: 775 PQAP 778 Score = 30.4 bits (67), Expect = 2.6 Identities = 18/38 (47%), Positives = 19/38 (50%), Gaps = 1/38 (2%) Query: 160 ACVLITPGDSKAVLPPTLPQPASHFPPPPPPPPLPPPP 197 A VL G V P+ P S FPPPPP LP PP Sbjct: 1050 APVLSGRGKDSVVEFPSPPSD-SDFPPPPPETELPLPP 1086 Score = 28.5 bits (62), Expect = 9.8 Identities = 12/24 (50%), Positives = 13/24 (54%), Gaps = 4/24 (16%) Query: 184 FPPPPPPPPLPPPPP----PLAPV 203 FP PP PPPPP PL P+ Sbjct: 1064 FPSPPSDSDFPPPPPETELPLPPI 1087 >gi|52485606 formin-like 2 [Homo sapiens] Length = 1092 Score = 52.8 bits (125), Expect = 5e-07 Identities = 54/182 (29%), Positives = 74/182 (40%), Gaps = 45/182 (24%) Query: 172 VLPPTLPQPASHFPPPPPPPPLPPPP-----------PPLAPVLLRKPSLA--------- 211 V PP P P PPPPPPPP PPPP PPLAP L P L Sbjct: 548 VTPPMPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLAPPLPSAPPLPGTSSPTVVF 607 Query: 212 -KALQAGPLKKDGPMQITVKDLLTVKLKKTQ-------SLDEKRKL----------IPSP 253 L A +KK + + V LK Q +D++R L I Sbjct: 608 NSGLAAVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKT 667 Query: 254 KARNPLVTV-SDLQHVTLKPNSKVL---STRVTNVLIT---PGKSQMDLRKLLRKVDVER 306 KA+ P + + S Q + K ++KV + R N+ IT GK+ ++ K + D++ Sbjct: 668 KAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAITLRKAGKTADEICKAIHVFDLKT 727 Query: 307 SP 308 P Sbjct: 728 LP 729 Score = 50.8 bits (120), Expect = 2e-06 Identities = 30/72 (41%), Positives = 34/72 (47%), Gaps = 6/72 (8%) Query: 174 PPTLPQPASHFPPPPPPPPLPPPPPPLAP----VLLRKPSLAKALQAGP--LKKDGPMQI 227 P T P P PPPPPPPP PPPPPP P + P LA L + P P + Sbjct: 547 PVTPPMPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLAPPLPSAPPLPGTSSPTVV 606 Query: 228 TVKDLLTVKLKK 239 L VK+KK Sbjct: 607 FNSGLAAVKIKK 618 Score = 36.6 bits (83), Expect = 0.036 Identities = 16/32 (50%), Positives = 19/32 (59%), Gaps = 2/32 (6%) Query: 173 LPPT--LPQPASHFPPPPPPPPLPPPPPPLAP 202 LPP+ P+ + P PP PP PPPPPP P Sbjct: 533 LPPSSDTPETVQNGPVTPPMPPPPPPPPPPPP 564 Score = 32.7 bits (73), Expect = 0.52 Identities = 17/46 (36%), Positives = 20/46 (43%), Gaps = 18/46 (39%) Query: 175 PTLPQPASHFPPPPPPP------------------PLPPPPPPLAP 202 PT+ +S PPPPPP P+PPPPPP P Sbjct: 516 PTMGAASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPP 561 >gi|187761324 shootin1 isoform a [Homo sapiens] Length = 631 Score = 52.8 bits (125), Expect = 5e-07 Identities = 61/263 (23%), Positives = 109/263 (41%), Gaps = 45/263 (17%) Query: 109 HRELYSVKQQFCILESKLCKLQEALKTISESSSCPSCGQTCHMSGKLTNVPACVLITPGD 168 H+E++++KQQ +LE +L+ LK + + + K N Sbjct: 300 HKEIHNLKQQLELLEEDKKELE--LKYQNSEEKARNLKHSVDELQKRVN----------Q 347 Query: 169 SKAVLPPTLPQPASHFPPPPPPPPLPPPPP-PLAPVLLRKPSLAKALQAGPLKKDGPMQI 227 S+ +PP PPPPPPPLPPPPP P+ ++ + +G K+ Sbjct: 348 SENSVPP----------PPPPPPPLPPPPPNPIRSLMSMIRKRSHPSGSGAKKEKATQPE 397 Query: 228 TVKDLLTVKLKKTQSLDEKRK----LIPSPKARNPLV----------TVSDLQHVTLKPN 273 T +++ +K + + + ++ K L P + P V +L+ + N Sbjct: 398 TTEEVTDLKRQAVEEMMDRIKKGVHLRPVNQTARPKTKPESSKGCESAVDELKGILGTLN 457 Query: 274 SKVLSTRVTNVLITPGKSQMDLRKLLRKVDV-----ERSPGGTPLTNK-ENMETGTGLTP 327 S + + + P S+ +L ++LR+ V SP G T++ ++M ++ Sbjct: 458 KSTSSRSLKS--LDPENSETELERILRRRKVTAEADSSSPTGILATSESKSMPVLGSVSS 515 Query: 328 VMTQALRRKFQLAHPRSPTPTLP 350 V AL +K A SP+P P Sbjct: 516 VTKTALNKKTLEAEFNSPSPPTP 538 Score = 28.5 bits (62), Expect = 9.8 Identities = 14/37 (37%), Positives = 20/37 (54%), Gaps = 4/37 (10%) Query: 5 KQRRRKLKAKAERLFKKKEASHFQSKLITPPPPPPSP 41 +++ R LK + L K+ QS+ PPPPPP P Sbjct: 328 EEKARNLKHSVDELQKRVN----QSENSVPPPPPPPP 360 >gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] Length = 1682 Score = 52.0 bits (123), Expect = 8e-07 Identities = 30/56 (53%), Positives = 31/56 (55%), Gaps = 7/56 (12%) Query: 173 LPPTLPQPASHFPPPPPPPPLPPPP-PPLA---PVLLRKPSLAKALQA---GPLKK 221 LPP LP P PPPPPPPP PPPP P LA P L KP L L GP +K Sbjct: 240 LPPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERK 295 Score = 43.5 bits (101), Expect = 3e-04 Identities = 22/42 (52%), Positives = 24/42 (57%), Gaps = 1/42 (2%) Query: 174 PPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQ 215 PP LP P PPP P PPPPPP +P L K SLA L+ Sbjct: 772 PPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLK-SLASVLE 812 Score = 35.0 bits (79), Expect = 0.10 Identities = 19/45 (42%), Positives = 26/45 (57%), Gaps = 4/45 (8%) Query: 178 PQPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPLKKD 222 P P+S PPPPP P L PPPP P L+ P+ A + G + ++ Sbjct: 463 PGPSS--PPPPPCPRLLRPPPP--PAWLKGPACRAAREDGEILEE 503 Score = 31.2 bits (69), Expect = 1.5 Identities = 20/58 (34%), Positives = 25/58 (43%), Gaps = 3/58 (5%) Query: 174 PPTL---PQPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPLKKDGPMQIT 228 PP L P P+ PPPPPPP LA VL + + A + GP+ T Sbjct: 778 PPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTT 835 Score = 29.6 bits (65), Expect = 4.4 Identities = 17/34 (50%), Positives = 18/34 (52%), Gaps = 1/34 (2%) Query: 175 PTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKP 208 P L PA+ PP P PPPPP P LLR P Sbjct: 448 PFLGAPAATPHLSLPPGPSSPPPPP-CPRLLRPP 480 Score = 29.6 bits (65), Expect = 4.4 Identities = 25/80 (31%), Positives = 28/80 (35%), Gaps = 30/80 (37%) Query: 159 PACVLITPGDSKAVLPPTLPQPA---------SH---------FPPPP---------PPP 191 P + G + PPT P P SH FPPPP P P Sbjct: 528 PPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRP 587 Query: 192 PLP---PPPPPLAPVLLRKP 208 P P P PPL P+ L P Sbjct: 588 PSPAQNPQDPPLVPLTLALP 607 Score = 29.6 bits (65), Expect = 4.4 Identities = 30/138 (21%), Positives = 49/138 (35%), Gaps = 25/138 (18%) Query: 175 PTLPQPASHFP------PPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGP-------LKK 221 P P+P FP P PPP PL P P+ P + P+ L P ++ Sbjct: 625 PESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEE 684 Query: 222 DGPMQITVKDLLTVKLKKTQSLDEKRK-------LIPSPKARNPLVTV-----SDLQHVT 269 +I L + +S+ ++ + + P P + P ++ +D T Sbjct: 685 PAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTT 744 Query: 270 LKPNSKVLSTRVTNVLIT 287 P V +T T T Sbjct: 745 TAPAVAVTTTTTTTTTTT 762 >gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] Length = 1263 Score = 51.6 bits (122), Expect = 1e-06 Identities = 24/53 (45%), Positives = 27/53 (50%) Query: 166 PGDSKAVLPPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGP 218 PGDS ++PP S PPPPPPPP PPPP P + PSL P Sbjct: 580 PGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISP 632 Score = 43.5 bits (101), Expect = 3e-04 Identities = 36/106 (33%), Positives = 45/106 (42%), Gaps = 24/106 (22%) Query: 112 LYSVKQQFCI----LESKLCKLQ-EALKTISESSSCPSCGQTCHMSGKLTNVPACVLITP 166 L+S KQQ LE+++ +L E K E + +S VP V Sbjct: 514 LHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKK--EMASLSAAAITVPPSV---- 567 Query: 167 GDSKAVLPPTLPQPASH---FPP---------PPPPPPLPPPPPPL 200 S+A +PP P P PP PPPPPP PPPPPPL Sbjct: 568 -PSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPL 612 Score = 41.2 bits (95), Expect = 0.001 Identities = 25/56 (44%), Positives = 27/56 (48%), Gaps = 4/56 (7%) Query: 166 PGDSKAVLPPTLPQPASHFPPPPPPP---PLPPPPPPLAPVLLRKPSLAKALQAGP 218 PG + PP LP A PPPPP P +PPPPPPL P P L GP Sbjct: 661 PGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPL-PGEAGMPPPPPPLPGGP 715 Score = 37.0 bits (84), Expect = 0.027 Identities = 23/63 (36%), Positives = 29/63 (46%), Gaps = 19/63 (30%) Query: 157 NVPACVLITP-----GDSKAVLPPTLPQ----------PASHFPPPPPPPP----LPPPP 197 ++P I+P GD+ PP LP+ P PPPPP P +PPPP Sbjct: 623 SLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP 682 Query: 198 PPL 200 PPL Sbjct: 683 PPL 685 Score = 36.2 bits (82), Expect = 0.047 Identities = 17/29 (58%), Positives = 18/29 (62%), Gaps = 5/29 (17%) Query: 174 PPTLPQPASHFPPPPPP----PPLPPPPP 198 PP LP A PPPPPP P +PPPPP Sbjct: 695 PPPLPGEAG-MPPPPPPLPGGPGIPPPPP 722 Score = 35.8 bits (81), Expect = 0.061 Identities = 19/38 (50%), Positives = 20/38 (52%), Gaps = 5/38 (13%) Query: 166 PGDSKAVLPPTLPQPASHFPPPPPPP----PLPPPPPP 199 PG S + PP P P PPPPPP P PPPPP Sbjct: 686 PG-SAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPP 722 Score = 35.8 bits (81), Expect = 0.061 Identities = 22/47 (46%), Positives = 23/47 (48%), Gaps = 16/47 (34%) Query: 174 PPTLPQPASHFPPPP-------PPPP----LPPPPP-----PLAPVL 204 PP LP PPPP PPPP +PPPPP P APVL Sbjct: 708 PPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVL 754 Score = 35.0 bits (79), Expect = 0.10 Identities = 22/60 (36%), Positives = 24/60 (40%), Gaps = 25/60 (41%) Query: 166 PGDSKAVLPPTLPQPASHFPPP--------PPPPPLP-----------------PPPPPL 200 PG PP+LP + PPP PPPPPLP PPPPPL Sbjct: 613 PGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPL 672 Score = 31.2 bits (69), Expect = 1.5 Identities = 19/43 (44%), Positives = 19/43 (44%), Gaps = 14/43 (32%) Query: 174 PPTLPQPASHFPPPPP---------PPPLPP-----PPPPLAP 202 PP LP A PPPPP PPP P PPPP P Sbjct: 682 PPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFP 724 Score = 28.5 bits (62), Expect = 9.8 Identities = 12/16 (75%), Positives = 12/16 (75%) Query: 33 TPPPPPPSPERVGISS 48 T PPPPP PE VGI S Sbjct: 641 TIPPPPPLPEGVGIPS 656 >gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] Length = 1272 Score = 51.6 bits (122), Expect = 1e-06 Identities = 24/53 (45%), Positives = 27/53 (50%) Query: 166 PGDSKAVLPPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGP 218 PGDS ++PP S PPPPPPPP PPPP P + PSL P Sbjct: 589 PGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISP 641 Score = 43.5 bits (101), Expect = 3e-04 Identities = 36/106 (33%), Positives = 45/106 (42%), Gaps = 24/106 (22%) Query: 112 LYSVKQQFCI----LESKLCKLQ-EALKTISESSSCPSCGQTCHMSGKLTNVPACVLITP 166 L+S KQQ LE+++ +L E K E + +S VP V Sbjct: 523 LHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKK--EMASLSAAAITVPPSV---- 576 Query: 167 GDSKAVLPPTLPQPASH---FPP---------PPPPPPLPPPPPPL 200 S+A +PP P P PP PPPPPP PPPPPPL Sbjct: 577 -PSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPL 621 Score = 41.2 bits (95), Expect = 0.001 Identities = 25/56 (44%), Positives = 27/56 (48%), Gaps = 4/56 (7%) Query: 166 PGDSKAVLPPTLPQPASHFPPPPPPP---PLPPPPPPLAPVLLRKPSLAKALQAGP 218 PG + PP LP A PPPPP P +PPPPPPL P P L GP Sbjct: 670 PGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPL-PGEAGMPPPPPPLPGGP 724 Score = 37.0 bits (84), Expect = 0.027 Identities = 23/63 (36%), Positives = 29/63 (46%), Gaps = 19/63 (30%) Query: 157 NVPACVLITP-----GDSKAVLPPTLPQ----------PASHFPPPPPPPP----LPPPP 197 ++P I+P GD+ PP LP+ P PPPPP P +PPPP Sbjct: 632 SLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP 691 Query: 198 PPL 200 PPL Sbjct: 692 PPL 694 Score = 36.2 bits (82), Expect = 0.047 Identities = 17/29 (58%), Positives = 18/29 (62%), Gaps = 5/29 (17%) Query: 174 PPTLPQPASHFPPPPPP----PPLPPPPP 198 PP LP A PPPPPP P +PPPPP Sbjct: 704 PPPLPGEAG-MPPPPPPLPGGPGIPPPPP 731 Score = 35.8 bits (81), Expect = 0.061 Identities = 19/38 (50%), Positives = 20/38 (52%), Gaps = 5/38 (13%) Query: 166 PGDSKAVLPPTLPQPASHFPPPPPPP----PLPPPPPP 199 PG S + PP P P PPPPPP P PPPPP Sbjct: 695 PG-SAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPP 731 Score = 35.8 bits (81), Expect = 0.061 Identities = 22/47 (46%), Positives = 23/47 (48%), Gaps = 16/47 (34%) Query: 174 PPTLPQPASHFPPPP-------PPPP----LPPPPP-----PLAPVL 204 PP LP PPPP PPPP +PPPPP P APVL Sbjct: 717 PPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVL 763 Score = 35.0 bits (79), Expect = 0.10 Identities = 22/60 (36%), Positives = 24/60 (40%), Gaps = 25/60 (41%) Query: 166 PGDSKAVLPPTLPQPASHFPPP--------PPPPPLP-----------------PPPPPL 200 PG PP+LP + PPP PPPPPLP PPPPPL Sbjct: 622 PGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPL 681 Score = 31.2 bits (69), Expect = 1.5 Identities = 19/43 (44%), Positives = 19/43 (44%), Gaps = 14/43 (32%) Query: 174 PPTLPQPASHFPPPPP---------PPPLPP-----PPPPLAP 202 PP LP A PPPPP PPP P PPPP P Sbjct: 691 PPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFP 733 Score = 28.5 bits (62), Expect = 9.8 Identities = 12/16 (75%), Positives = 12/16 (75%) Query: 33 TPPPPPPSPERVGISS 48 T PPPPP PE VGI S Sbjct: 650 TIPPPPPLPEGVGIPS 665 >gi|195947369 junction-mediating and regulatory protein [Homo sapiens] Length = 988 Score = 51.6 bits (122), Expect = 1e-06 Identities = 36/105 (34%), Positives = 50/105 (47%), Gaps = 20/105 (19%) Query: 126 LCKLQEALKTISESSSCPSCGQTCHMSGKLT------NVPAC-VLITPGDSKAVLPPTLP 178 L +L++ T E++S P G T + ++ N+ C V I P LP Sbjct: 755 LVQLEDTSLTQLEATSLPLSGVTSELPPTISLPLLNNNLEPCSVTINP----------LP 804 Query: 179 QPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPLKKDG 223 P PPPPPPPP PPPPPPL + K S + L+ +K+G Sbjct: 805 SPLPPTPPPPPPPPPPPPPPPLP---VAKDSGPETLEKDLPRKEG 846 Score = 34.7 bits (78), Expect = 0.14 Identities = 26/66 (39%), Positives = 30/66 (45%), Gaps = 17/66 (25%) Query: 173 LPPTLPQPASH------------FPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGP-- 218 LPPT+ P + P P PP P PPPPPP P P L A +GP Sbjct: 780 LPPTISLPLLNNNLEPCSVTINPLPSPLPPTP-PPPPPPPPPP--PPPPLPVAKDSGPET 836 Query: 219 LKKDGP 224 L+KD P Sbjct: 837 LEKDLP 842 >gi|126090663 zinc finger homeodomain 4 [Homo sapiens] Length = 3571 Score = 51.2 bits (121), Expect = 1e-06 Identities = 22/35 (62%), Positives = 24/35 (68%), Gaps = 3/35 (8%) Query: 174 PPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKP 208 PPT P P PPPPPPPP PPPPPP AP ++ P Sbjct: 1994 PPTPPPPP---PPPPPPPPPPPPPPPSAPPQVQLP 2025 Score = 45.1 bits (105), Expect = 1e-04 Identities = 18/26 (69%), Positives = 18/26 (69%), Gaps = 4/26 (15%) Query: 174 PPTLPQPASHFPPPPPPPPLPPPPPP 199 PP P P PPPPPPPP PPPPPP Sbjct: 1993 PPPTPPP----PPPPPPPPPPPPPPP 2014 Score = 44.3 bits (103), Expect = 2e-04 Identities = 28/72 (38%), Positives = 32/72 (44%), Gaps = 25/72 (34%) Query: 173 LPPTLPQPASHFP-------------------PPPPPPPLPPPPPPLAPVLLRKPSLAKA 213 LPP PQP+S P PPPPPPP PPPPPP P PS Sbjct: 1967 LPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPP-----PSAPPQ 2021 Query: 214 LQAGPLKKDGPM 225 +Q P+ D P+ Sbjct: 2022 VQL-PVSLDLPL 2032 Score = 41.6 bits (96), Expect = 0.001 Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 6/92 (6%) Query: 165 TPGDSKAVLPPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKP----SLAKALQAGPLK 220 TP + PP P P PPPPPPPP PP PV L P + + +Q L Sbjct: 1988 TPLQAPPPTPPPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALP 2047 Query: 221 KDGPMQITVKDLLTVKLKKTQSLDEKRKLIPS 252 +Q+ D L+ L TQ ++ L P+ Sbjct: 2048 PQLALQLPQMDALSADL--TQLCQQQLGLDPN 2077 Score = 40.8 bits (94), Expect = 0.002 Identities = 22/49 (44%), Positives = 27/49 (55%), Gaps = 4/49 (8%) Query: 173 LPPTLPQPASHFPPPPPPPPLPPPPP---PLAPVLLRKPSLAKALQAGP 218 L P P PPPPPPPPLPP PP + PV + +++ LQA P Sbjct: 1947 LYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPN-TVSTPLQAPP 1994 Score = 35.4 bits (80), Expect = 0.080 Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 2/68 (2%) Query: 179 QPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPLKKDGPMQITVKDLLTVKLK 238 +P PPPPPPPP PPP L+ + + K + K + +I ++L K + Sbjct: 3111 KPLLQTPPPPPPPPPPPPSSSLSGQQTEQQN--KESEKKQTKPNKVKKIKEEELEATKPE 3168 Query: 239 KTQSLDEK 246 K +EK Sbjct: 3169 KHPKKEEK 3176 Score = 30.0 bits (66), Expect = 3.4 Identities = 12/20 (60%), Positives = 13/20 (65%) Query: 175 PTLPQPASHFPPPPPPPPLP 194 PT P + PPPPPPPP P Sbjct: 3109 PTKPLLQTPPPPPPPPPPPP 3128 Score = 28.5 bits (62), Expect = 9.8 Identities = 23/63 (36%), Positives = 27/63 (42%), Gaps = 5/63 (7%) Query: 140 SSCPSCGQTCHMSGKLTNVPACVLITPGDSKAVLPPTLPQPASHFPPPPPPPPLPPPPPP 199 SS P Q S LT A +L P + A P L ++ P PP PPPPPP Sbjct: 3071 SSLPGFPQN---SNTLTPPGAGMLGFP--TSATSSPALSLSSAPTKPLLQTPPPPPPPPP 3125 Query: 200 LAP 202 P Sbjct: 3126 PPP 3128 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 50.8 bits (120), Expect = 2e-06 Identities = 27/53 (50%), Positives = 27/53 (50%), Gaps = 8/53 (15%) Query: 174 PPTLPQPASHFPPP--------PPPPPLPPPPPPLAPVLLRKPSLAKALQAGP 218 PP PQPA PPP PPPPPLPPPPPP P P A A A P Sbjct: 1474 PPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAP 1526 Score = 41.2 bits (95), Expect = 0.001 Identities = 17/29 (58%), Positives = 18/29 (62%) Query: 174 PPTLPQPASHFPPPPPPPPLPPPPPPLAP 202 P PQP PPPPP P LP PPP +AP Sbjct: 1463 PAPTPQPQPPPPPPPPQPALPSPPPLVAP 1491 Score = 40.0 bits (92), Expect = 0.003 Identities = 19/43 (44%), Positives = 19/43 (44%), Gaps = 14/43 (32%) Query: 174 PPTLPQPASHFPPPPPPP--------------PLPPPPPPLAP 202 PP P P PPPPPPP P PPPPPL P Sbjct: 1461 PPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPP 1503 Score = 40.0 bits (92), Expect = 0.003 Identities = 20/44 (45%), Positives = 20/44 (45%), Gaps = 1/44 (2%) Query: 166 PGDSKAVLPPTLPQPASHFPPPPPPP-PLPPPPPPLAPVLLRKP 208 P V P P PPPPPP P PPPPPP A L P Sbjct: 1483 PSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAP 1526 Score = 39.7 bits (91), Expect = 0.004 Identities = 23/43 (53%), Positives = 24/43 (55%), Gaps = 8/43 (18%) Query: 174 PPTL--PQPASHFPPP-PPPPPL-----PPPPPPLAPVLLRKP 208 PP L P P+S PPP PPPPP PPPPPP A L P Sbjct: 1485 PPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPP 1527 Score = 38.5 bits (88), Expect = 0.009 Identities = 16/36 (44%), Positives = 22/36 (61%) Query: 165 TPGDSKAVLPPTLPQPASHFPPPPPPPPLPPPPPPL 200 +P S + + L +PA+ P PPPP PPPPPP+ Sbjct: 811 SPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPM 846 Score = 37.7 bits (86), Expect = 0.016 Identities = 17/36 (47%), Positives = 19/36 (52%) Query: 165 TPGDSKAVLPPTLPQPASHFPPPPPPPPLPPPPPPL 200 +P SK + P P PPPPPP PPPP PL Sbjct: 813 SPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPL 848 Score = 37.7 bits (86), Expect = 0.016 Identities = 19/45 (42%), Positives = 20/45 (44%), Gaps = 5/45 (11%) Query: 174 PPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGP 218 PP P PA P P P PPPPPP P L P L + P Sbjct: 1457 PPPTPPPA-----PTPQPQPPPPPPPPQPALPSPPPLVAPTPSSP 1496 Score = 37.7 bits (86), Expect = 0.016 Identities = 19/46 (41%), Positives = 20/46 (43%), Gaps = 6/46 (13%) Query: 163 LITPGDSKAVLPPTLPQPASHFPPPPPPPP------LPPPPPPLAP 202 L+ P S PP P P P PPPPPP PP P AP Sbjct: 1488 LVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAP 1533 Score = 36.2 bits (82), Expect = 0.047 Identities = 15/26 (57%), Positives = 15/26 (57%) Query: 174 PPTLPQPASHFPPPPPPPPLPPPPPP 199 P L Q H PPPPPP PPPP P Sbjct: 1026 PLGLIQSGPHQAAPPPPPPPPPPPAP 1051 Score = 35.4 bits (80), Expect = 0.080 Identities = 23/62 (37%), Positives = 24/62 (38%), Gaps = 24/62 (38%) Query: 168 DSKAVLPPT----LPQPASHFPPP--------------------PPPPPLPPPPPPLAPV 203 D VLPP LP SH P P P PPP PPPPPP P+ Sbjct: 789 DLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPL 848 Query: 204 LL 205 L Sbjct: 849 QL 850 Score = 35.0 bits (79), Expect = 0.10 Identities = 17/41 (41%), Positives = 18/41 (43%), Gaps = 12/41 (29%) Query: 174 PPTLPQPASHFP------------PPPPPPPLPPPPPPLAP 202 PP LP + P PPPPPPP PPP P P Sbjct: 1015 PPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEP 1055 Score = 34.3 bits (77), Expect = 0.18 Identities = 14/29 (48%), Positives = 15/29 (51%) Query: 174 PPTLPQPASHFPPPPPPPPLPPPPPPLAP 202 PP L + PPP P P PPPPP P Sbjct: 1450 PPLLEEKPPPTPPPAPTPQPQPPPPPPPP 1478 Score = 32.3 bits (72), Expect = 0.68 Identities = 16/36 (44%), Positives = 17/36 (47%), Gaps = 9/36 (25%) Query: 163 LITPGDSKAVLPPTLPQPASHFPPPPPPPPLPPPPP 198 LI G +A PP PPPPPPPP P P Sbjct: 1029 LIQSGPHQAAPPP---------PPPPPPPPAPASEP 1055 Score = 28.9 bits (63), Expect = 7.5 Identities = 21/45 (46%), Positives = 21/45 (46%), Gaps = 4/45 (8%) Query: 172 VLPPTLPQPASHFPPPPPPPPLPPPPPPLAPV---LLRKPSLAKA 213 VL P PA PP P PP PPPPP P LL S A A Sbjct: 213 VLGPAGLGPAQT-PPYRPGPPDPPPPPRHLPTQFNLLASSSAAAA 256 Score = 28.9 bits (63), Expect = 7.5 Identities = 17/39 (43%), Positives = 21/39 (53%), Gaps = 4/39 (10%) Query: 174 PPTLPQ-PASHFPPPPPPPPL---PPPPPPLAPVLLRKP 208 PP LP P+++ P PP L PPP PP AP +P Sbjct: 1433 PPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQP 1471 >gi|150378503 leiomodin 2 (cardiac) [Homo sapiens] Length = 547 Score = 50.4 bits (119), Expect = 2e-06 Identities = 32/106 (30%), Positives = 49/106 (46%), Gaps = 16/106 (15%) Query: 169 SKAVLPPTLPQPASHFPPPPPP-----PPLPPPPPP-----------LAPVLLRKPSLAK 212 S+ + P P P PPPPPP PP PPPPPP +A V+ ++ S + Sbjct: 412 SRPLSPVATPPPPPPPPPPPPPSSQRLPPPPPPPPPPLPEKKLITRNIAEVIKQQESAQR 471 Query: 213 ALQAGPLKKDGPMQITVKDLLTVKLKKTQSLDEKRKLIPSPKARNP 258 ALQ G KK G + + ++K + +++K+ S + P Sbjct: 472 ALQNGQKKKKGKKVKKQPNSILKEIKNSLRSVQEKKMEDSSRPSTP 517 >gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] Length = 502 Score = 50.1 bits (118), Expect = 3e-06 Identities = 40/109 (36%), Positives = 51/109 (46%), Gaps = 7/109 (6%) Query: 173 LPPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKAL-QAGPLKKDGPMQITVKD 231 LPP P P + PP PPPPP PPPPPP + P L AL AG L G + Sbjct: 381 LPP--PPPGAGGPPMPPPPP-PPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQ 437 Query: 232 LLT-VKLKKTQSLDEKRKLIPSPKARNPLVTVSDLQHVTLKPNSKVLST 279 + ++L KT E L P P++ L V L HV K + + S+ Sbjct: 438 IRQGIQLNKTPGAPESSALQPPPQSSEGL--VGALMHVMQKRSRAIHSS 484 Score = 31.6 bits (70), Expect = 1.2 Identities = 19/42 (45%), Positives = 20/42 (47%), Gaps = 7/42 (16%) Query: 167 GDSKAVLPPTLPQPASHFPPPP-----PPP--PLPPPPPPLA 201 G +K P P P PPPP PPP PPPPPP A Sbjct: 333 GGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPA 374 >gi|122937271 WAS protein homolog associated with actin, golgi membranes and microtubules [Homo sapiens] Length = 809 Score = 50.1 bits (118), Expect = 3e-06 Identities = 34/91 (37%), Positives = 41/91 (45%), Gaps = 21/91 (23%) Query: 143 PSCGQTCHMSGKLTNVPACVLITPGDSKAVLPPTLPQPASHFPPPPPPPPLPPPPPPLAP 202 P C Q CH N+P V + GD + PPPPPPPP PPPPPP P Sbjct: 607 PKC-QNCH-----GNIPVQVFVPVGDQTH----SKSSEELSLPPPPPPPPPPPPPPPPPP 656 Query: 203 VLLRKPSLAKALQA---------GPLKKDGP 224 LR +L+ + QA P+K D P Sbjct: 657 PPLR--ALSSSSQAATHQNLGFRAPVKDDQP 685 >gi|15812226 transcriptional regulating factor 1 [Homo sapiens] Length = 1200 Score = 50.1 bits (118), Expect = 3e-06 Identities = 39/119 (32%), Positives = 51/119 (42%), Gaps = 21/119 (17%) Query: 168 DSKAVLPPTLPQPASHFPPPPPPPPLPPPPPPLAPVLL----------RKPS---LAKAL 214 + + VLPP P PPPPPPP LPP L P+++ KPS + Sbjct: 547 EGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNST 606 Query: 215 QAGPLKKDGPMQITVKDLLTVKLKKTQSLDEKRKLIPS-PKARNPLVTVSDLQHVTLKP 272 A P +D P D + V L+ RK PS PKA PL TV + + +P Sbjct: 607 VAAPSARDKPASSMSDDEMPV-------LEIPRKHQPSVPKAEEPLKTVQEKKKFRHRP 658 >gi|119120861 formin-like 3 isoform 2 [Homo sapiens] Length = 976 Score = 49.7 bits (117), Expect = 4e-06 Identities = 38/143 (26%), Positives = 59/143 (41%), Gaps = 27/143 (18%) Query: 110 RELYSVKQQFCILESKLCKLQEALKTISESSSCPSCGQTCHMSGKLTNVP-----ACVLI 164 +EL S+K+ + ++ L+ +K E+ + CH+ + + A + Sbjct: 384 KELESIKETYENTSHQVHTLRRLIKEKEEAFQ-----RRCHLEPNVRGLESVDSEALARV 438 Query: 165 TPGDSKAVLPPT-------LPQPASHFP-PPPPPPPLPPPPPPLAPVLLRKPSLAKALQA 216 P + +PP+ P P P PPPP PPLPPPPPPL K A Sbjct: 439 GPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPD---------KCPPA 489 Query: 217 GPLKKDGPMQITVKDLLTVKLKK 239 PL P + L +++KK Sbjct: 490 PPLPGAAPSVVLTVGLSAIRIKK 512 >gi|119120874 formin-like 3 isoform 1 [Homo sapiens] Length = 1027 Score = 49.7 bits (117), Expect = 4e-06 Identities = 38/143 (26%), Positives = 59/143 (41%), Gaps = 27/143 (18%) Query: 110 RELYSVKQQFCILESKLCKLQEALKTISESSSCPSCGQTCHMSGKLTNVP-----ACVLI 164 +EL S+K+ + ++ L+ +K E+ + CH+ + + A + Sbjct: 435 KELESIKETYENTSHQVHTLRRLIKEKEEAFQ-----RRCHLEPNVRGLESVDSEALARV 489 Query: 165 TPGDSKAVLPPT-------LPQPASHFP-PPPPPPPLPPPPPPLAPVLLRKPSLAKALQA 216 P + +PP+ P P P PPPP PPLPPPPPPL K A Sbjct: 490 GPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPD---------KCPPA 540 Query: 217 GPLKKDGPMQITVKDLLTVKLKK 239 PL P + L +++KK Sbjct: 541 PPLPGAAPSVVLTVGLSAIRIKK 563 >gi|56549694 enabled homolog isoform a [Homo sapiens] Length = 591 Score = 48.5 bits (114), Expect = 9e-06 Identities = 22/36 (61%), Positives = 24/36 (66%), Gaps = 5/36 (13%) Query: 174 PPTLPQPASHFPPPPPPPPL-----PPPPPPLAPVL 204 PP P P++ PPPPPPPPL PPPPPP AP L Sbjct: 337 PPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPL 372 Score = 43.5 bits (101), Expect = 3e-04 Identities = 28/77 (36%), Positives = 30/77 (38%), Gaps = 18/77 (23%) Query: 165 TPGDSKAVLPPTLPQPASHFPP--------------PPPPPPLP----PPPPPLAPVLLR 206 TP VL P P P PP PPPPPPLP PPPPP P+ + Sbjct: 300 TPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQ 359 Query: 207 KPSLAKALQAGPLKKDG 223 P A PL G Sbjct: 360 VPPPPPPPPAPPLPASG 376 Score = 37.7 bits (86), Expect = 0.016 Identities = 26/69 (37%), Positives = 30/69 (43%), Gaps = 13/69 (18%) Query: 173 LPPTLPQPASHFPP-----PPPPPPLPPPPPPLAPVLLRKPS--------LAKALQAGPL 219 LP T P P PP PPPPPP P PP P + L S LA A+ L Sbjct: 342 LPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDNRPLTGLAAAIAGAKL 401 Query: 220 KKDGPMQIT 228 +K M+ T Sbjct: 402 RKVSRMEDT 410 Score = 28.5 bits (62), Expect = 9.8 Identities = 19/59 (32%), Positives = 20/59 (33%) Query: 166 PGDSKAVLPPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPLKKDGP 224 PG A P P P PPP PP PP A + P PL GP Sbjct: 289 PGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGP 347 >gi|39930375 enabled homolog isoform b [Homo sapiens] Length = 570 Score = 48.5 bits (114), Expect = 9e-06 Identities = 22/36 (61%), Positives = 24/36 (66%), Gaps = 5/36 (13%) Query: 174 PPTLPQPASHFPPPPPPPPL-----PPPPPPLAPVL 204 PP P P++ PPPPPPPPL PPPPPP AP L Sbjct: 337 PPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPL 372 Score = 43.5 bits (101), Expect = 3e-04 Identities = 28/77 (36%), Positives = 30/77 (38%), Gaps = 18/77 (23%) Query: 165 TPGDSKAVLPPTLPQPASHFPP--------------PPPPPPLP----PPPPPLAPVLLR 206 TP VL P P P PP PPPPPPLP PPPPP P+ + Sbjct: 300 TPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQ 359 Query: 207 KPSLAKALQAGPLKKDG 223 P A PL G Sbjct: 360 VPPPPPPPPAPPLPASG 376 Score = 37.7 bits (86), Expect = 0.016 Identities = 26/69 (37%), Positives = 30/69 (43%), Gaps = 13/69 (18%) Query: 173 LPPTLPQPASHFPP-----PPPPPPLPPPPPPLAPVLLRKPS--------LAKALQAGPL 219 LP T P P PP PPPPPP P PP P + L S LA A+ L Sbjct: 342 LPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDNRPLTGLAAAIAGAKL 401 Query: 220 KKDGPMQIT 228 +K M+ T Sbjct: 402 RKVSRMEDT 410 Score = 28.5 bits (62), Expect = 9.8 Identities = 19/59 (32%), Positives = 20/59 (33%) Query: 166 PGDSKAVLPPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPLKKDGP 224 PG A P P P PPP PP PP A + P PL GP Sbjct: 289 PGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGP 347 >gi|116256475 zinc finger protein 827 [Homo sapiens] Length = 1077 Score = 48.1 bits (113), Expect = 1e-05 Identities = 20/35 (57%), Positives = 23/35 (65%) Query: 174 PPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKP 208 PP+ +P PPPPPPPP PPPPPP + LL P Sbjct: 318 PPSEKKPEKVTPPPPPPPPPPPPPPPQSLELLLLP 352 Score = 41.2 bits (95), Expect = 0.001 Identities = 19/38 (50%), Positives = 23/38 (60%), Gaps = 6/38 (15%) Query: 168 DSKAVLP--PTLPQPASHFP----PPPPPPPLPPPPPP 199 + ++LP P P P+ P PPPPPPP PPPPPP Sbjct: 305 EKSSLLPEDPLPPPPSEKKPEKVTPPPPPPPPPPPPPP 342 Score = 40.8 bits (94), Expect = 0.002 Identities = 17/31 (54%), Positives = 20/31 (64%) Query: 178 PQPASHFPPPPPPPPLPPPPPPLAPVLLRKP 208 P+ + PPPPPPPP PPPP L +LL P Sbjct: 324 PEKVTPPPPPPPPPPPPPPPQSLELLLLPVP 354 >gi|6382071 diaphanous 2 isoform 12C [Homo sapiens] Length = 1096 Score = 48.1 bits (113), Expect = 1e-05 Identities = 33/97 (34%), Positives = 45/97 (46%), Gaps = 5/97 (5%) Query: 111 ELYSVKQQFCILESKLCKLQEALKTISESSSCPSCGQTCHMSGKLTNVPACVLITPGDSK 170 EL ++ LE+++ +L+ + +S SS P + G P PG + Sbjct: 517 ELQKRDEKIKELEAEIQQLRTQAQVLSSSSGIPGPPAAPPLPGVGPPPPPPAPPLPGGAP 576 Query: 171 AVLPPTLPQPASHFPPPPPPPPL----PPPPPPLAPV 203 + PP P P PPPPPPPL PPPPPPL V Sbjct: 577 -LPPPPPPLPGMMGIPPPPPPPLLFGGPPPPPPLGGV 612 Score = 39.7 bits (91), Expect = 0.004 Identities = 19/40 (47%), Positives = 21/40 (52%), Gaps = 5/40 (12%) Query: 174 PPTLPQPASHFPPPPPPPPLP-----PPPPPLAPVLLRKP 208 P P P PPPPP PPLP PPPPP P ++ P Sbjct: 552 PAAPPLPGVGPPPPPPAPPLPGGAPLPPPPPPLPGMMGIP 591 Score = 39.3 bits (90), Expect = 0.006 Identities = 22/53 (41%), Positives = 25/53 (47%), Gaps = 8/53 (15%) Query: 174 PPTLPQPASHFPPPPPPPP-------LPPPPPPLAPVL-LRKPSLAKALQAGP 218 PP P PPPPPP P LPPPPPPL ++ + P L GP Sbjct: 551 PPAAPPLPGVGPPPPPPAPPLPGGAPLPPPPPPLPGMMGIPPPPPPPLLFGGP 603 >gi|5803003 diaphanous 2 isoform 156 [Homo sapiens] Length = 1101 Score = 48.1 bits (113), Expect = 1e-05 Identities = 33/97 (34%), Positives = 45/97 (46%), Gaps = 5/97 (5%) Query: 111 ELYSVKQQFCILESKLCKLQEALKTISESSSCPSCGQTCHMSGKLTNVPACVLITPGDSK 170 EL ++ LE+++ +L+ + +S SS P + G P PG + Sbjct: 517 ELQKRDEKIKELEAEIQQLRTQAQVLSSSSGIPGPPAAPPLPGVGPPPPPPAPPLPGGAP 576 Query: 171 AVLPPTLPQPASHFPPPPPPPPL----PPPPPPLAPV 203 + PP P P PPPPPPPL PPPPPPL V Sbjct: 577 -LPPPPPPLPGMMGIPPPPPPPLLFGGPPPPPPLGGV 612 Score = 39.7 bits (91), Expect = 0.004 Identities = 19/40 (47%), Positives = 21/40 (52%), Gaps = 5/40 (12%) Query: 174 PPTLPQPASHFPPPPPPPPLP-----PPPPPLAPVLLRKP 208 P P P PPPPP PPLP PPPPP P ++ P Sbjct: 552 PAAPPLPGVGPPPPPPAPPLPGGAPLPPPPPPLPGMMGIP 591 Score = 39.3 bits (90), Expect = 0.006 Identities = 22/53 (41%), Positives = 25/53 (47%), Gaps = 8/53 (15%) Query: 174 PPTLPQPASHFPPPPPPPP-------LPPPPPPLAPVL-LRKPSLAKALQAGP 218 PP P PPPPPP P LPPPPPPL ++ + P L GP Sbjct: 551 PPAAPPLPGVGPPPPPPAPPLPGGAPLPPPPPPLPGMMGIPPPPPPPLLFGGP 603 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 48.1 bits (113), Expect = 1e-05 Identities = 22/44 (50%), Positives = 28/44 (63%), Gaps = 1/44 (2%) Query: 159 PACVLITPGDSKAVLPPTLPQPASHFPPPPPPPPLPPPPPPLAP 202 P +++TPG + AV P++ P PPPP PPLPPPPPP P Sbjct: 657 PKPMVVTPG-AAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPP 699 Score = 47.0 bits (110), Expect = 3e-05 Identities = 21/43 (48%), Positives = 22/43 (51%) Query: 166 PGDSKAVLPPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKP 208 PG PP P P FP PPP PP PPPPPP P + P Sbjct: 685 PGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPP 727 Score = 41.2 bits (95), Expect = 0.001 Identities = 26/58 (44%), Positives = 28/58 (48%), Gaps = 1/58 (1%) Query: 172 VLPPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPLKKDGPMQITV 229 V PP LP P PPPP PPLPP PP L PV+ S Q G + MQ V Sbjct: 725 VPPPPLPAPPG-VPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQV 781 Score = 39.7 bits (91), Expect = 0.004 Identities = 19/43 (44%), Positives = 24/43 (55%), Gaps = 5/43 (11%) Query: 185 PPPPPPPPLPPPPPPLAPVLLRKPSL-----AKALQAGPLKKD 222 PP PP PP PPPPPP+ P L L ++A+ GP +D Sbjct: 1541 PPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRD 1583 Score = 38.5 bits (88), Expect = 0.009 Identities = 19/42 (45%), Positives = 21/42 (50%), Gaps = 6/42 (14%) Query: 175 PTLPQPASHFPPPPPPPP------LPPPPPPLAPVLLRKPSL 210 P P P PPPPPPPP +PPPP P P + P L Sbjct: 701 PGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPIL 742 Score = 38.5 bits (88), Expect = 0.009 Identities = 20/51 (39%), Positives = 26/51 (50%), Gaps = 9/51 (17%) Query: 162 VLITPGDSKAVLPPTLPQPAS--------HFPPPPPP-PPLPPPPPPLAPV 203 +L+ PG + + P+ P + P PPPP PP PPPPPP PV Sbjct: 1506 LLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPV 1556 Score = 38.1 bits (87), Expect = 0.012 Identities = 24/70 (34%), Positives = 26/70 (37%), Gaps = 19/70 (27%) Query: 156 TNVPACVLITPGDSKAVLPPTLPQPASHFPPPPPPP-----------------PLPPPPP 198 T PA PG A P P +HFPPPP P P PPP P Sbjct: 381 TPPPAQATPAPGFKSAFSP--YQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLP 438 Query: 199 PLAPVLLRKP 208 P P+ KP Sbjct: 439 PAEPLAKEKP 448 Score = 37.7 bits (86), Expect = 0.016 Identities = 20/43 (46%), Positives = 22/43 (51%), Gaps = 1/43 (2%) Query: 174 PPTLPQPASHFPPPP-PPPPLPPPPPPLAPVLLRKPSLAKALQ 215 PP PA PPPP P PP PPPP L P+ P L +Q Sbjct: 715 PPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQ 757 Score = 33.1 bits (74), Expect = 0.40 Identities = 15/26 (57%), Positives = 15/26 (57%), Gaps = 1/26 (3%) Query: 174 PPTLPQPASHFPPPPPPPPLPPPPPP 199 P LP P P PPP PP PP PPP Sbjct: 1271 PMMLPLPLQP-PLPPPRPPRPPSPPP 1295 Score = 31.6 bits (70), Expect = 1.2 Identities = 21/61 (34%), Positives = 24/61 (39%), Gaps = 8/61 (13%) Query: 173 LPPTLPQP--------ASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPLKKDGP 224 LP LP P A P P PP LP P P + RKP + L DGP Sbjct: 1433 LPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGP 1492 Query: 225 M 225 + Sbjct: 1493 L 1493 Score = 30.0 bits (66), Expect = 3.4 Identities = 20/65 (30%), Positives = 26/65 (40%), Gaps = 14/65 (21%) Query: 173 LPPTLPQPASHFPPPPPP---------PPLPPPP-----PPLAPVLLRKPSLAKALQAGP 218 L P LP P PP PPP P +PP P PP P L + +++ + P Sbjct: 1278 LQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVP 1337 Query: 219 LKKDG 223 G Sbjct: 1338 ATPGG 1342 Score = 28.9 bits (63), Expect = 7.5 Identities = 23/74 (31%), Positives = 27/74 (36%), Gaps = 15/74 (20%) Query: 166 PGDSKAVLPPTLPQPASHF-----PPPPPP------PPLPPPPPPLAPVLLRKPSLAKA- 213 P PP P+ A P PP PPLPPP PP P +P A Sbjct: 1244 PAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDAS 1303 Query: 214 ---LQAGPLKKDGP 224 + PL +D P Sbjct: 1304 HPSVPPEPLAEDHP 1317 >gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3 [Homo sapiens] Length = 650 Score = 47.4 bits (111), Expect = 2e-05 Identities = 32/98 (32%), Positives = 43/98 (43%), Gaps = 8/98 (8%) Query: 174 PPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPLK-------KDGPMQ 226 PP P PAS PPPPPPP P PP P LL SL + Q PL P + Sbjct: 385 PPPPPPPASQQPPPPPPPQAPVRLPPGGP-LLPSASLTRGPQPPPLAVTVPSSLPQSPPE 443 Query: 227 ITVKDLLTVKLKKTQSLDEKRKLIPSPKARNPLVTVSD 264 + + + + +L + R SP ++P VS+ Sbjct: 444 NPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSN 481 >gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1 [Homo sapiens] Length = 634 Score = 47.4 bits (111), Expect = 2e-05 Identities = 32/98 (32%), Positives = 43/98 (43%), Gaps = 8/98 (8%) Query: 174 PPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPLK-------KDGPMQ 226 PP P PAS PPPPPPP P PP P LL SL + Q PL P + Sbjct: 369 PPPPPPPASQQPPPPPPPQAPVRLPPGGP-LLPSASLTRGPQPPPLAVTVPSSLPQSPPE 427 Query: 227 ITVKDLLTVKLKKTQSLDEKRKLIPSPKARNPLVTVSD 264 + + + + +L + R SP ++P VS+ Sbjct: 428 NPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSN 465 >gi|11386183 WAS protein family, member 2 [Homo sapiens] Length = 498 Score = 47.4 bits (111), Expect = 2e-05 Identities = 19/32 (59%), Positives = 20/32 (62%) Query: 168 DSKAVLPPTLPQPASHFPPPPPPPPLPPPPPP 199 D + PP L QP PPPPPPPP P PPPP Sbjct: 374 DYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPP 405 Score = 42.0 bits (97), Expect = 9e-04 Identities = 22/47 (46%), Positives = 24/47 (51%), Gaps = 10/47 (21%) Query: 166 PGDSKAVLPPTLPQPASHFP--PPPP--------PPPLPPPPPPLAP 202 P A PP P PA+ +P PPPP PPP PPPPPP P Sbjct: 357 PHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPP 403 Score = 38.5 bits (88), Expect = 0.009 Identities = 18/39 (46%), Positives = 19/39 (48%), Gaps = 5/39 (12%) Query: 166 PGDSKAVLPPTLPQPASHFPPPPPP-----PPLPPPPPP 199 PG + PP P P PPPPPP P PPPP P Sbjct: 314 PGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSP 352 Score = 37.7 bits (86), Expect = 0.016 Identities = 18/35 (51%), Positives = 18/35 (51%), Gaps = 4/35 (11%) Query: 178 PQPASHFPPPPPPPPLPPP----PPPLAPVLLRKP 208 P P F PPP PPP PPP PPP PV P Sbjct: 310 PGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSP 344 Score = 37.0 bits (84), Expect = 0.027 Identities = 16/35 (45%), Positives = 18/35 (51%), Gaps = 5/35 (14%) Query: 166 PGDSKAVLPPTLPQPASHFPPPPPPPPLPPPPPPL 200 PG PP P P PPPP +PPPPPP+ Sbjct: 310 PGPKPGFAPPPAPPP-----PPPPMIGIPPPPPPV 339 Score = 37.0 bits (84), Expect = 0.027 Identities = 20/60 (33%), Positives = 24/60 (40%) Query: 165 TPGDSKAVLPPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPLKKDGP 224 +PG PP+ P PPPPPPP P L P L +P+ P GP Sbjct: 343 SPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGP 402 Score = 34.7 bits (78), Expect = 0.14 Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 7/37 (18%) Query: 171 AVLPPTLPQPASHFPPPP-------PPPPLPPPPPPL 200 +V+ P+ P PA PP PPP PPPPPP+ Sbjct: 293 SVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPM 329 >gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] Length = 1303 Score = 47.4 bits (111), Expect = 2e-05 Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 7/87 (8%) Query: 162 VLITPGDSKAVLPPTLP--QPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPL 219 +L TP PT P +P PPPPPPPP PPP PP P+ + +P L L Sbjct: 516 LLPTPPRPPGPQAPTSPNGRPMQGGPPPPPPPPPPPPGPPQMPMPVHEP-----LSPQQL 570 Query: 220 KKDGPMQITVKDLLTVKLKKTQSLDEK 246 ++ + L + ++ T L EK Sbjct: 571 QQQDMYNKKIPSLFEIVVRPTGQLAEK 597 Score = 41.6 bits (96), Expect = 0.001 Identities = 18/30 (60%), Positives = 19/30 (63%), Gaps = 1/30 (3%) Query: 174 PPTLPQPASHFPPPP-PPPPLPPPPPPLAP 202 P T P P S PPPP PPPP P PPP +P Sbjct: 5 PGTPPPPPSESPPPPSPPPPSTPSPPPCSP 34 Score = 28.5 bits (62), Expect = 9.8 Identities = 15/40 (37%), Positives = 20/40 (50%), Gaps = 5/40 (12%) Query: 166 PGDSKAVLPPTLPQPASHFPPPPPPPPLPPPPPPLAPVLL 205 P S++ PP+ P P++ P PPP P P P LL Sbjct: 10 PPPSESPPPPSPPPPST-----PSPPPCSPDARPATPHLL 44 >gi|40807465 zinc finger protein 341 [Homo sapiens] Length = 847 Score = 47.4 bits (111), Expect = 2e-05 Identities = 20/30 (66%), Positives = 21/30 (70%), Gaps = 3/30 (10%) Query: 173 LPPTLPQPASHFPPPPPPPPLPPPPPPLAP 202 +P L QP PPPPPPPPLPPPPPP P Sbjct: 171 VPSYLTQPP---PPPPPPPPLPPPPPPQPP 197 Score = 43.9 bits (102), Expect = 2e-04 Identities = 23/58 (39%), Positives = 27/58 (46%), Gaps = 4/58 (6%) Query: 174 PPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQ----AGPLKKDGPMQI 227 PP P P PPPPPP P PPPP L P P ++ A PL G ++I Sbjct: 178 PPPPPPPPPPLPPPPPPQPPPPPPQSLGPPGRPNPGGNGVVEVYSAAAPLAGSGTVEI 235 >gi|55741677 SET domain containing 1A [Homo sapiens] Length = 1707 Score = 47.0 bits (110), Expect = 3e-05 Identities = 26/57 (45%), Positives = 29/57 (50%), Gaps = 3/57 (5%) Query: 168 DSKAVLPPTLPQPASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPLKKDGP 224 D + PP P P PPPPPPP PPPPP LA + L P A P + DGP Sbjct: 588 DDRGGSPPPAPTPPQQPPPPPPPP--PPPPPYLASLPLGYPPHQPAYLLPP-RPDGP 641 Score = 34.7 bits (78), Expect = 0.14 Identities = 19/34 (55%), Positives = 19/34 (55%), Gaps = 5/34 (14%) Query: 171 AVLPPTLP--QPASHFPPPP---PPPPLPPPPPP 199 A LP P QPA PP P PPP PPPPPP Sbjct: 619 ASLPLGYPPHQPAYLLPPRPDGPPPPEYPPPPPP 652 Score = 33.5 bits (75), Expect = 0.30 Identities = 14/25 (56%), Positives = 14/25 (56%) Query: 174 PPTLPQPASHFPPPPPPPPLPPPPP 198 P L P PPPP PP PPPPP Sbjct: 630 PAYLLPPRPDGPPPPEYPPPPPPPP 654 Score = 28.5 bits (62), Expect = 9.8 Identities = 11/17 (64%), Positives = 11/17 (64%) Query: 182 SHFPPPPPPPPLPPPPP 198 SH PPPP PPPPP Sbjct: 1396 SHARRRRPPPPPPPPPP 1412 Score = 28.5 bits (62), Expect = 9.8 Identities = 10/15 (66%), Positives = 10/15 (66%) Query: 188 PPPPPLPPPPPPLAP 202 PPPPP PPPP P Sbjct: 1403 PPPPPPPPPPRAYEP 1417 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.132 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,271,957 Number of Sequences: 37866 Number of extensions: 1279461 Number of successful extensions: 48298 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 910 Number of HSP's successfully gapped in prelim test: 533 Number of HSP's that attempted gapping in prelim test: 17323 Number of HSP's gapped (non-prelim): 16048 length of query: 360 length of database: 18,247,518 effective HSP length: 103 effective length of query: 257 effective length of database: 14,347,320 effective search space: 3687261240 effective search space used: 3687261240 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.