Guide to the Human Genome
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Search of human proteins with 88501738

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo
sapiens]
         (2365 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sap...  4858   0.0  
gi|88501740 TRIO and F-actin binding protein isoform 1 [Homo sap...  1174   0.0  
gi|88501741 TRIO and F-actin binding protein isoform 2 [Homo sap...   676   0.0  
gi|50980301 myosin phosphatase-Rho interacting protein isoform 2...   474   e-133
gi|50980307 myosin phosphatase-Rho interacting protein isoform 1...   474   e-133
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]       172   5e-42
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]         155   4e-37
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...   132   4e-30
gi|163965366 nascent polypeptide-associated complex alpha subuni...   104   9e-22
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]   103   3e-21
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                  101   1e-20
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                  101   1e-20
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]        100   2e-20
gi|239753963 PREDICTED: similar to apopolysialoglycoprotein [Hom...    98   8e-20
gi|151301154 mucin 6, gastric [Homo sapiens]                           97   2e-19
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   95   7e-19
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    95   7e-19
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    93   3e-18
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]        92   5e-18
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        91   1e-17
gi|91982772 mucin 17 [Homo sapiens]                                    88   9e-17
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    86   4e-16
gi|238624188 diffuse panbronchiolitis critical region 1 protein ...    85   7e-16
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    84   1e-15
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]        84   2e-15
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit...    81   1e-14
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    81   1e-14
gi|239742580 PREDICTED: similar to Putative POM121-like protein ...    80   2e-14
gi|239744133 PREDICTED: hypothetical protein [Homo sapiens]            79   7e-14
gi|239742514 PREDICTED: similar to Putative POM121-like protein ...    77   2e-13

>gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sapiens]
          Length = 2365

 Score = 4858 bits (12600), Expect = 0.0
 Identities = 2365/2365 (100%), Positives = 2365/2365 (100%)

Query: 1    MEEVPGDALCEHFEANILTQNRCQNCFHPEEAHGARYQELRSPSGAEVPYCDLPRCPPAP 60
            MEEVPGDALCEHFEANILTQNRCQNCFHPEEAHGARYQELRSPSGAEVPYCDLPRCPPAP
Sbjct: 1    MEEVPGDALCEHFEANILTQNRCQNCFHPEEAHGARYQELRSPSGAEVPYCDLPRCPPAP 60

Query: 61   EDPLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTAAPRSRSRELEAVPYLEGLTT 120
            EDPLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTAAPRSRSRELEAVPYLEGLTT
Sbjct: 61   EDPLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTAAPRSRSRELEAVPYLEGLTT 120

Query: 121  SLCGSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPRE 180
            SLCGSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPRE
Sbjct: 121  SLCGSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPRE 180

Query: 181  GPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRSTL 240
            GPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRSTL
Sbjct: 181  GPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRSTL 240

Query: 241  TQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEIS 300
            TQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEIS
Sbjct: 241  TQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEIS 300

Query: 301  RASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQ 360
            RASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQ
Sbjct: 301  RASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQ 360

Query: 361  QDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSSP 420
            QDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSSP
Sbjct: 361  QDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSSP 420

Query: 421  NRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTS 480
            NRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTS
Sbjct: 421  NRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTS 480

Query: 481  CAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASS 540
            CAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASS
Sbjct: 481  CAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASS 540

Query: 541  PNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTT 600
            PNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTT
Sbjct: 541  PNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTT 600

Query: 601  SCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRA 660
            SCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRA
Sbjct: 601  SCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRA 660

Query: 661  SSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENP 720
            SSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENP
Sbjct: 661  SSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENP 720

Query: 721  RTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRT 780
            RTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRT
Sbjct: 721  RTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRT 780

Query: 781  SSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTK 840
            SSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTK
Sbjct: 781  SSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTK 840

Query: 841  RDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRT 900
            RDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRT
Sbjct: 841  RDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRT 900

Query: 901  NKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDP 960
            NKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDP
Sbjct: 901  NKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDP 960

Query: 961  PQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGH 1020
            PQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGH
Sbjct: 961  PQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGH 1020

Query: 1021 RDAPRASSPPRYLQHDPFPFFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHT 1080
            RDAPRASSPPRYLQHDPFPFFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHT
Sbjct: 1021 RDAPRASSPPRYLQHDPFPFFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHT 1080

Query: 1081 QFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQDLP 1140
            QFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQDLP
Sbjct: 1081 QFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQDLP 1140

Query: 1141 RASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLA 1200
            RASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLA
Sbjct: 1141 RASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLA 1200

Query: 1201 PSTDSLHGSPVLIPQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGE 1260
            PSTDSLHGSPVLIPQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGE
Sbjct: 1201 PSTDSLHGSPVLIPQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGE 1260

Query: 1261 TRHNLEREEYTVLADLPPPRRLAQRQPGPQAQCSSGGRTHSPGRAEVERLFGQERRKSEA 1320
            TRHNLEREEYTVLADLPPPRRLAQRQPGPQAQCSSGGRTHSPGRAEVERLFGQERRKSEA
Sbjct: 1261 TRHNLEREEYTVLADLPPPRRLAQRQPGPQAQCSSGGRTHSPGRAEVERLFGQERRKSEA 1320

Query: 1321 AGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPSRQVTMLPAKQAELTRRSQAEPPHPWSPE 1380
            AGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPSRQVTMLPAKQAELTRRSQAEPPHPWSPE
Sbjct: 1321 AGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPSRQVTMLPAKQAELTRRSQAEPPHPWSPE 1380

Query: 1381 KRPEGDRQLQGSPLPPRTSARTPERELRTQRPLESGQAGPRQPLGVWQSQEEPPGSQGPH 1440
            KRPEGDRQLQGSPLPPRTSARTPERELRTQRPLESGQAGPRQPLGVWQSQEEPPGSQGPH
Sbjct: 1381 KRPEGDRQLQGSPLPPRTSARTPERELRTQRPLESGQAGPRQPLGVWQSQEEPPGSQGPH 1440

Query: 1441 RHLERSWSSQEGGLGPGGWWGCGEPSLGAAKAPEGAWGGTSREYKESWGQPEAWEEKPTH 1500
            RHLERSWSSQEGGLGPGGWWGCGEPSLGAAKAPEGAWGGTSREYKESWGQPEAWEEKPTH
Sbjct: 1441 RHLERSWSSQEGGLGPGGWWGCGEPSLGAAKAPEGAWGGTSREYKESWGQPEAWEEKPTH 1500

Query: 1501 ELPRELGKRSPLTSPPENWGGPAESSQSWHSGTPTAVGWGAEGACPYPRGSERRPELDWR 1560
            ELPRELGKRSPLTSPPENWGGPAESSQSWHSGTPTAVGWGAEGACPYPRGSERRPELDWR
Sbjct: 1501 ELPRELGKRSPLTSPPENWGGPAESSQSWHSGTPTAVGWGAEGACPYPRGSERRPELDWR 1560

Query: 1561 DLLGLLRAPGEGVWARVPSLDWEGLLELLQARLPRKDPAGHRDDLARALGPELGPPGTND 1620
            DLLGLLRAPGEGVWARVPSLDWEGLLELLQARLPRKDPAGHRDDLARALGPELGPPGTND
Sbjct: 1561 DLLGLLRAPGEGVWARVPSLDWEGLLELLQARLPRKDPAGHRDDLARALGPELGPPGTND 1620

Query: 1621 VPEQESHSQPEGWAEATPVNGHSPALQSQSPVQLPSPACTSTQWPKIKVTRGPATATLAG 1680
            VPEQESHSQPEGWAEATPVNGHSPALQSQSPVQLPSPACTSTQWPKIKVTRGPATATLAG
Sbjct: 1621 VPEQESHSQPEGWAEATPVNGHSPALQSQSPVQLPSPACTSTQWPKIKVTRGPATATLAG 1680

Query: 1681 LEQTGPLGSRSTAKGPSLPELQFQPEEPEESEPSRGQDPLTDQKQADSADKRPAEGKAGS 1740
            LEQTGPLGSRSTAKGPSLPELQFQPEEPEESEPSRGQDPLTDQKQADSADKRPAEGKAGS
Sbjct: 1681 LEQTGPLGSRSTAKGPSLPELQFQPEEPEESEPSRGQDPLTDQKQADSADKRPAEGKAGS 1740

Query: 1741 PLKGRLVTSWRMPGDRPTLFNPFLLSLGVLRWRRPDLLNFKKGWMSILDEPGEPPSPSLT 1800
            PLKGRLVTSWRMPGDRPTLFNPFLLSLGVLRWRRPDLLNFKKGWMSILDEPGEPPSPSLT
Sbjct: 1741 PLKGRLVTSWRMPGDRPTLFNPFLLSLGVLRWRRPDLLNFKKGWMSILDEPGEPPSPSLT 1800

Query: 1801 TTSTSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHT 1860
            TTSTSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHT
Sbjct: 1801 TTSTSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHT 1860

Query: 1861 KDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDSNKENALHSYSTQKGPLKAGE 1920
            KDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDSNKENALHSYSTQKGPLKAGE
Sbjct: 1861 KDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDSNKENALHSYSTQKGPLKAGE 1920

Query: 1921 QRAGSEVISRGGPRKADGQRQALDYVELSPLTQASPQRARTPARTPDRLAKQEELERDLA 1980
            QRAGSEVISRGGPRKADGQRQALDYVELSPLTQASPQRARTPARTPDRLAKQEELERDLA
Sbjct: 1921 QRAGSEVISRGGPRKADGQRQALDYVELSPLTQASPQRARTPARTPDRLAKQEELERDLA 1980

Query: 1981 QRSEERRKWFEATDSRTPEVPAGEGPRRGLGAPLTEDQQNRLSEEIEKKWQELEKLPLRE 2040
            QRSEERRKWFEATDSRTPEVPAGEGPRRGLGAPLTEDQQNRLSEEIEKKWQELEKLPLRE
Sbjct: 1981 QRSEERRKWFEATDSRTPEVPAGEGPRRGLGAPLTEDQQNRLSEEIEKKWQELEKLPLRE 2040

Query: 2041 NKRVPLTALLNQSRGERRGPPSDGHEALEKEVQALRAQLEAWRLQGEAPQSALRSQEDGH 2100
            NKRVPLTALLNQSRGERRGPPSDGHEALEKEVQALRAQLEAWRLQGEAPQSALRSQEDGH
Sbjct: 2041 NKRVPLTALLNQSRGERRGPPSDGHEALEKEVQALRAQLEAWRLQGEAPQSALRSQEDGH 2100

Query: 2101 IPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEKEWLLAEETAATASAIE 2160
            IPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEKEWLLAEETAATASAIE
Sbjct: 2101 IPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEKEWLLAEETAATASAIE 2160

Query: 2161 AMKKAYQEELSRELSKTRSLQQGPDGLRKQHQSDVEALKRELQVLSEQYSQKCLEIGALM 2220
            AMKKAYQEELSRELSKTRSLQQGPDGLRKQHQSDVEALKRELQVLSEQYSQKCLEIGALM
Sbjct: 2161 AMKKAYQEELSRELSKTRSLQQGPDGLRKQHQSDVEALKRELQVLSEQYSQKCLEIGALM 2220

Query: 2221 RQAEEREHTLRRCQQEGQELLRHNQELHGRLSEEIDQLRGFIASQGMGNGCGRSNERSSC 2280
            RQAEEREHTLRRCQQEGQELLRHNQELHGRLSEEIDQLRGFIASQGMGNGCGRSNERSSC
Sbjct: 2221 RQAEEREHTLRRCQQEGQELLRHNQELHGRLSEEIDQLRGFIASQGMGNGCGRSNERSSC 2280

Query: 2281 ELEVLLRVKENELQYLKKEVQCLRDELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREIE 2340
            ELEVLLRVKENELQYLKKEVQCLRDELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREIE
Sbjct: 2281 ELEVLLRVKENELQYLKKEVQCLRDELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREIE 2340

Query: 2341 QLKEHLRLAMAALQEKESMRNSLAE 2365
            QLKEHLRLAMAALQEKESMRNSLAE
Sbjct: 2341 QLKEHLRLAMAALQEKESMRNSLAE 2365


>gi|88501740 TRIO and F-actin binding protein isoform 1 [Homo sapiens]
          Length = 652

 Score = 1174 bits (3038), Expect = 0.0
 Identities = 604/642 (94%), Positives = 608/642 (94%), Gaps = 2/642 (0%)

Query: 1724 KQADSADKRPAEGKAGSPLKGRLVTSWRMPGDRPTLFNPFLLSLGVLRWRRPDLLNFKKG 1783
            K+   A +R AE   G    G  V + R P   P   +  LL         PDLLNFKKG
Sbjct: 13   KEGPEARRRAAERGGGGGGGG--VPAPRSPAREPRPRSCLLLPPPWGAAMTPDLLNFKKG 70

Query: 1784 WMSILDEPGEPPSPSLTTTSTSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCT 1843
            WMSILDEPGEPPSPSLTTTSTSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCT
Sbjct: 71   WMSILDEPGEPPSPSLTTTSTSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCT 130

Query: 1844 DVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDSNKE 1903
            DVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDSNKE
Sbjct: 131  DVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDSNKE 190

Query: 1904 NALHSYSTQKGPLKAGEQRAGSEVISRGGPRKADGQRQALDYVELSPLTQASPQRARTPA 1963
            NALHSYSTQKGPLKAGEQRAGSEVISRGGPRKADGQRQALDYVELSPLTQASPQRARTPA
Sbjct: 191  NALHSYSTQKGPLKAGEQRAGSEVISRGGPRKADGQRQALDYVELSPLTQASPQRARTPA 250

Query: 1964 RTPDRLAKQEELERDLAQRSEERRKWFEATDSRTPEVPAGEGPRRGLGAPLTEDQQNRLS 2023
            RTPDRLAKQEELERDLAQRSEERRKWFEATDSRTPEVPAGEGPRRGLGAPLTEDQQNRLS
Sbjct: 251  RTPDRLAKQEELERDLAQRSEERRKWFEATDSRTPEVPAGEGPRRGLGAPLTEDQQNRLS 310

Query: 2024 EEIEKKWQELEKLPLRENKRVPLTALLNQSRGERRGPPSDGHEALEKEVQALRAQLEAWR 2083
            EEIEKKWQELEKLPLRENKRVPLTALLNQSRGERRGPPSDGHEALEKEVQALRAQLEAWR
Sbjct: 311  EEIEKKWQELEKLPLRENKRVPLTALLNQSRGERRGPPSDGHEALEKEVQALRAQLEAWR 370

Query: 2084 LQGEAPQSALRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQE 2143
            LQGEAPQSALRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQE
Sbjct: 371  LQGEAPQSALRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQE 430

Query: 2144 KEWLLAEETAATASAIEAMKKAYQEELSRELSKTRSLQQGPDGLRKQHQSDVEALKRELQ 2203
            KEWLLAEETAATASAIEAMKKAYQEELSRELSKTRSLQQGPDGLRKQHQSDVEALKRELQ
Sbjct: 431  KEWLLAEETAATASAIEAMKKAYQEELSRELSKTRSLQQGPDGLRKQHQSDVEALKRELQ 490

Query: 2204 VLSEQYSQKCLEIGALMRQAEEREHTLRRCQQEGQELLRHNQELHGRLSEEIDQLRGFIA 2263
            VLSEQYSQKCLEIGALMRQAEEREHTLRRCQQEGQELLRHNQELHGRLSEEIDQLRGFIA
Sbjct: 491  VLSEQYSQKCLEIGALMRQAEEREHTLRRCQQEGQELLRHNQELHGRLSEEIDQLRGFIA 550

Query: 2264 SQGMGNGCGRSNERSSCELEVLLRVKENELQYLKKEVQCLRDELQMMQKDKRFTSGKYQD 2323
            SQGMGNGCGRSNERSSCELEVLLRVKENELQYLKKEVQCLRDELQMMQKDKRFTSGKYQD
Sbjct: 551  SQGMGNGCGRSNERSSCELEVLLRVKENELQYLKKEVQCLRDELQMMQKDKRFTSGKYQD 610

Query: 2324 VYVELSHIKTRSEREIEQLKEHLRLAMAALQEKESMRNSLAE 2365
            VYVELSHIKTRSEREIEQLKEHLRLAMAALQEKESMRNSLAE
Sbjct: 611  VYVELSHIKTRSEREIEQLKEHLRLAMAALQEKESMRNSLAE 652


>gi|88501741 TRIO and F-actin binding protein isoform 2 [Homo sapiens]
          Length = 431

 Score =  676 bits (1745), Expect = 0.0
 Identities = 347/385 (90%), Positives = 351/385 (91%), Gaps = 2/385 (0%)

Query: 1724 KQADSADKRPAEGKAGSPLKGRLVTSWRMPGDRPTLFNPFLLSLGVLRWRRPDLLNFKKG 1783
            K+   A +R AE   G    G  V + R P   P   +  LL         PDLLNFKKG
Sbjct: 13   KEGPEARRRAAERGGGGGGGG--VPAPRSPAREPRPRSCLLLPPPWGAAMTPDLLNFKKG 70

Query: 1784 WMSILDEPGEPPSPSLTTTSTSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCT 1843
            WMSILDEPGEPPSPSLTTTSTSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCT
Sbjct: 71   WMSILDEPGEPPSPSLTTTSTSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCT 130

Query: 1844 DVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDSNKE 1903
            DVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDSNKE
Sbjct: 131  DVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDSNKE 190

Query: 1904 NALHSYSTQKGPLKAGEQRAGSEVISRGGPRKADGQRQALDYVELSPLTQASPQRARTPA 1963
            NALHSYSTQKGPLKAGEQRAGSEVISRGGPRKADGQRQALDYVELSPLTQASPQRARTPA
Sbjct: 191  NALHSYSTQKGPLKAGEQRAGSEVISRGGPRKADGQRQALDYVELSPLTQASPQRARTPA 250

Query: 1964 RTPDRLAKQEELERDLAQRSEERRKWFEATDSRTPEVPAGEGPRRGLGAPLTEDQQNRLS 2023
            RTPDRLAKQEELERDLAQRSEERRKWFEATDSRTPEVPAGEGPRRGLGAPLTEDQQNRLS
Sbjct: 251  RTPDRLAKQEELERDLAQRSEERRKWFEATDSRTPEVPAGEGPRRGLGAPLTEDQQNRLS 310

Query: 2024 EEIEKKWQELEKLPLRENKRVPLTALLNQSRGERRGPPSDGHEALEKEVQALRAQLEAWR 2083
            EEIEKKWQELEKLPLRENKRVPLTALLNQSRGERRGPPSDGHEALEKEVQALRAQLEAWR
Sbjct: 311  EEIEKKWQELEKLPLRENKRVPLTALLNQSRGERRGPPSDGHEALEKEVQALRAQLEAWR 370

Query: 2084 LQGEAPQSALRSQEDGHIPPGYISQ 2108
            LQGEAPQSALRSQEDGHIPPGYISQ
Sbjct: 371  LQGEAPQSALRSQEDGHIPPGYISQ 395


>gi|50980301 myosin phosphatase-Rho interacting protein isoform 2
            [Homo sapiens]
          Length = 1025

 Score =  474 bits (1219), Expect = e-133
 Identities = 293/703 (41%), Positives = 400/703 (56%), Gaps = 81/703 (11%)

Query: 1685 GPLGSRSTAKGPSLPEL-----QFQPEEPEESEPSRGQDPLTDQKQADSADKRPAEGKAG 1739
            GP  S  T +G S          F  E P    P     PL+  ++A S D+R  E    
Sbjct: 324  GPSPSSDTRQGRSEKRAFPRKRDFTNEAPPAPLPDASASPLSPHRRAKSLDRRSTEPSV- 382

Query: 1740 SPLKGRLVTSWRMPGDRPTLFNPFLLSLGVLRWRRPDLLNFKKGWMSILDEPGEPPSPSL 1799
                                               PDLLNFKKGW++   E G       
Sbjct: 383  ----------------------------------TPDLLNFKKGWLTKQYEDG------- 401

Query: 1800 TTTSTSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVTEYAVQRNYGFQIH 1859
                  QWKKHWFVL D SL+YYRDS AEEA +LDGEIDL +C DVTEY VQRNYGFQIH
Sbjct: 402  ------QWKKHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDVTEYPVQRNYGFQIH 455

Query: 1860 TKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDSNKENALHSYSTQKGPLKAG 1919
            TK+  +TLSAMTSGIRRNWI+ + K V PT+APDVT      K  +  S+ T   P +  
Sbjct: 456  TKEGEFTLSAMTSGIRRNWIQTIMKHVHPTTAPDVTSSLPEEKNKSSCSFETCPRPTEKQ 515

Query: 1920 EQRAG----SEVISRGGPRKADGQRQALDYVELSPLTQASPQR---ARTPARTPDRL--- 1969
            E   G     +  SR   R+ +G+ +  D+ E  P+ QA  Q       PA T + L   
Sbjct: 516  EAELGEPDPEQKRSRARERRREGRSKTFDWAEFRPIQQALAQERVGGVGPADTHEPLRPE 575

Query: 1970 AKQEELERDLAQRSEERRKWF---EATDS-RTPEVPAGEGPRRGLGAPLTEDQQNRLSEE 2025
            A+  ELER+ A+R EERRK F   +ATD   T +        R  G P+++ + + +  E
Sbjct: 576  AEPGELERERARRREERRKRFGMLDATDGPGTEDAALRMEVDRSPGLPMSDLKTHNVHVE 635

Query: 2026 IEKKWQELEKLPLRENKRVPLTAL-LNQSRGERRGPPSDGHEALEKEVQALRAQ----LE 2080
            IE++W ++E  PLRE K+VP+  + L+   G  R    +    LEKE++  + +    LE
Sbjct: 636  IEQRWHQVETTPLREEKQVPIAPVHLSSEDGGDRLSTHELTSLLEKELEQSQKEASDLLE 695

Query: 2081 AWRLQGEAPQSALRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRL 2140
              RL  +  + AL  ++      GY+ Q  CER  A ME +HQ+ +E+LQR H+REL++L
Sbjct: 696  QNRLLQDQLRVALGREQSAR--EGYVLQATCERGFAAMEETHQKKIEDLQRQHQRELEKL 753

Query: 2141 QQEKEWLLAEETAATASAIEAMKKAYQEELSRELSKTR-----SLQQGPDGLRKQHQSDV 2195
            ++EK+ LLAEETAAT SAIEAMK A++EE+ REL K++     S+    + LR+Q+  ++
Sbjct: 754  REEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQYLEEL 813

Query: 2196 EALKRELQVLSEQYSQKCLEIGALMRQAEEREHTLRRCQQEGQELLRHNQELHGRLSEEI 2255
            ++++REL+VLSEQYSQKCLE   L +  E     LR+CQ+E QEL  HNQEL+ RL+ EI
Sbjct: 814  QSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEI 873

Query: 2256 DQLRGFIASQGMGNGCGR--SNERSSCELEVLLRVKENELQYLKKEVQCLRDELQMMQKD 2313
             +LR  +   G G   G   +  + + ELEVLLRVKE+E+QYLK+E+  L+DELQ   +D
Sbjct: 874  TRLRTLLTGDGGGEATGSPLAQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRD 933

Query: 2314 KRFTSGKYQDVYVELSHIKTRSEREIEQLKEHLRLAMAALQEK 2356
            K++ S KY+D+Y ELS  K +++ +I +LKE L+ A  AL EK
Sbjct: 934  KKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEK 976



 Score = 38.9 bits (89), Expect = 0.061
 Identities = 13/24 (54%), Positives = 18/24 (75%)

Query: 10 CEHFEANILTQNRCQNCFHPEEAH 33
          C  F+ANI  +++CQNCF P E+H
Sbjct: 9  CRKFQANIFNKSKCQNCFKPRESH 32


>gi|50980307 myosin phosphatase-Rho interacting protein isoform 1
            [Homo sapiens]
          Length = 1038

 Score =  474 bits (1219), Expect = e-133
 Identities = 293/703 (41%), Positives = 400/703 (56%), Gaps = 81/703 (11%)

Query: 1685 GPLGSRSTAKGPSLPEL-----QFQPEEPEESEPSRGQDPLTDQKQADSADKRPAEGKAG 1739
            GP  S  T +G S          F  E P    P     PL+  ++A S D+R  E    
Sbjct: 324  GPSPSSDTRQGRSEKRAFPRKRDFTNEAPPAPLPDASASPLSPHRRAKSLDRRSTEPSV- 382

Query: 1740 SPLKGRLVTSWRMPGDRPTLFNPFLLSLGVLRWRRPDLLNFKKGWMSILDEPGEPPSPSL 1799
                                               PDLLNFKKGW++   E G       
Sbjct: 383  ----------------------------------TPDLLNFKKGWLTKQYEDG------- 401

Query: 1800 TTTSTSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVTEYAVQRNYGFQIH 1859
                  QWKKHWFVL D SL+YYRDS AEEA +LDGEIDL +C DVTEY VQRNYGFQIH
Sbjct: 402  ------QWKKHWFVLADQSLRYYRDSVAEEAADLDGEIDLSACYDVTEYPVQRNYGFQIH 455

Query: 1860 TKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDSNKENALHSYSTQKGPLKAG 1919
            TK+  +TLSAMTSGIRRNWI+ + K V PT+APDVT      K  +  S+ T   P +  
Sbjct: 456  TKEGEFTLSAMTSGIRRNWIQTIMKHVHPTTAPDVTSSLPEEKNKSSCSFETCPRPTEKQ 515

Query: 1920 EQRAG----SEVISRGGPRKADGQRQALDYVELSPLTQASPQR---ARTPARTPDRL--- 1969
            E   G     +  SR   R+ +G+ +  D+ E  P+ QA  Q       PA T + L   
Sbjct: 516  EAELGEPDPEQKRSRARERRREGRSKTFDWAEFRPIQQALAQERVGGVGPADTHEPLRPE 575

Query: 1970 AKQEELERDLAQRSEERRKWF---EATDS-RTPEVPAGEGPRRGLGAPLTEDQQNRLSEE 2025
            A+  ELER+ A+R EERRK F   +ATD   T +        R  G P+++ + + +  E
Sbjct: 576  AEPGELERERARRREERRKRFGMLDATDGPGTEDAALRMEVDRSPGLPMSDLKTHNVHVE 635

Query: 2026 IEKKWQELEKLPLRENKRVPLTAL-LNQSRGERRGPPSDGHEALEKEVQALRAQ----LE 2080
            IE++W ++E  PLRE K+VP+  + L+   G  R    +    LEKE++  + +    LE
Sbjct: 636  IEQRWHQVETTPLREEKQVPIAPVHLSSEDGGDRLSTHELTSLLEKELEQSQKEASDLLE 695

Query: 2081 AWRLQGEAPQSALRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRL 2140
              RL  +  + AL  ++      GY+ Q  CER  A ME +HQ+ +E+LQR H+REL++L
Sbjct: 696  QNRLLQDQLRVALGREQSAR--EGYVLQATCERGFAAMEETHQKKIEDLQRQHQRELEKL 753

Query: 2141 QQEKEWLLAEETAATASAIEAMKKAYQEELSRELSKTR-----SLQQGPDGLRKQHQSDV 2195
            ++EK+ LLAEETAAT SAIEAMK A++EE+ REL K++     S+    + LR+Q+  ++
Sbjct: 754  REEKDRLLAEETAATISAIEAMKNAHREEMERELEKSQRSQISSVNSDVEALRRQYLEEL 813

Query: 2196 EALKRELQVLSEQYSQKCLEIGALMRQAEEREHTLRRCQQEGQELLRHNQELHGRLSEEI 2255
            ++++REL+VLSEQYSQKCLE   L +  E     LR+CQ+E QEL  HNQEL+ RL+ EI
Sbjct: 814  QSVQRELEVLSEQYSQKCLENAHLAQALEAERQALRQCQRENQELNAHNQELNNRLAAEI 873

Query: 2256 DQLRGFIASQGMGNGCGR--SNERSSCELEVLLRVKENELQYLKKEVQCLRDELQMMQKD 2313
             +LR  +   G G   G   +  + + ELEVLLRVKE+E+QYLK+E+  L+DELQ   +D
Sbjct: 874  TRLRTLLTGDGGGEATGSPLAQGKDAYELEVLLRVKESEIQYLKQEISSLKDELQTALRD 933

Query: 2314 KRFTSGKYQDVYVELSHIKTRSEREIEQLKEHLRLAMAALQEK 2356
            K++ S KY+D+Y ELS  K +++ +I +LKE L+ A  AL EK
Sbjct: 934  KKYASDKYKDIYTELSIAKAKADCDISRLKEQLKAATEALGEK 976



 Score = 38.9 bits (89), Expect = 0.061
 Identities = 13/24 (54%), Positives = 18/24 (75%)

Query: 10 CEHFEANILTQNRCQNCFHPEEAH 33
          C  F+ANI  +++CQNCF P E+H
Sbjct: 9  CRKFQANIFNKSKCQNCFKPRESH 32


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score =  172 bits (435), Expect = 5e-42
 Identities = 332/1434 (23%), Positives = 536/1434 (37%), Gaps = 215/1434 (14%)

Query: 137  SPDSATPDDTSNSSSVDWDTVE-------RQEEEAPSWDELAVMIPRRPREGPRADSS-- 187
            SPD+      S++ S+    ++       R+   + S  E+   +PR P    R+ SS  
Sbjct: 1387 SPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPG 1446

Query: 188  -QRAPSLLTRSPVGGDAAGQKK-EDTGGGGRS---------AGQHWARLRGESGLSLERH 236
             +      +R  + G + G K    T   GRS         A     R R  S  S E +
Sbjct: 1447 LRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELN 1506

Query: 237  RSTLT--QASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASS 294
               LT  +  S +  S  + T ++    QR  + ++   ++  ++SP   ++ D+S  S 
Sbjct: 1507 NKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSK 1566

Query: 295  TQ-----QEISRASSTQQETSRASSTQEDTPRASSTQ-EDTPRASSTQWNTPRASSPSRS 348
             +     ++ SR+ S+ +  S++  +   +   SS + +D PRA+      PRA S S S
Sbjct: 1567 AKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAA------PRAQSGSDS 1620

Query: 349  TQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQ 408
            +              P+   P   P+R              +SS  R    E S ++ + 
Sbjct: 1621 S------------PEPKAPAPRALPRRSR----------SGSSSKGRGPSPEGSSSTESS 1658

Query: 409  RDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRA-SRTS 467
             ++P  SRT+   R +R +P      R  PR     R++R +P  +   R + R+ S +S
Sbjct: 1659 PEHPPKSRTA--RRGSRSSPEPKTKSRTPPR----RRSSRSSPELTRKARLSRRSRSASS 1712

Query: 468  SPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPR 527
            SP   +R  PR     R +P  SSP  A +   +       +PR   TS   R+    PR
Sbjct: 1713 SPETRSRTPPR----HRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPR 1768

Query: 528  TSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDN------PRTSCAQ 581
                 R   R     R  R    +  +Q  + R  R+ S +R TR           S A+
Sbjct: 1769 GLQRSRSRSRREK-TRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPAR 1827

Query: 582  RDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNR 641
            +++ R SS  R  R     +  +R   R    +SP    R   R S A     R+ +P  
Sbjct: 1828 QESSRTSSRRRRGRSRTPPTSRKRSRSR----TSPAPWKRSRSRASPATHRRSRSRTPLI 1883

Query: 642  TTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCA 701
            + ++   RTS   R   R S  + T ++   R S   R   R+ +P  T ++   RT   
Sbjct: 1884 SRRRSRSRTSPVSRRRSR-SRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTT 1942

Query: 702  QRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNR 761
            +R   R+ +P  T ++   RT    R   R+ +   T +R   RTS   R   R+ +   
Sbjct: 1943 RRRS-RSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPV 2001

Query: 762  TIQQENLRTS-CTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQ 820
            T ++   RTS  TR+ +   + P    R   RT    R   R+ SP+   ++   RT   
Sbjct: 2002 TRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRT--- 2058

Query: 821  QNIPRSSSTQQDNPKT-SCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENL- 878
               PR++  ++   ++    +R +   + + R R+ +    R++ G+ +         + 
Sbjct: 2059 ---PRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMS 2115

Query: 879  ---RPS-SPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGP--------RTSSPSR 926
               RPS SP    +  +P    P  +++           +  DGP        RTS P  
Sbjct: 2116 CFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPEN 2175

Query: 927  SKQSEVPWASIALR-PTQGDRPQTSSPSRPAQHD------PPQSSFGPTQYNLPSRATSS 979
              QS +  A  A+   T    P  S+    A+        P  S       NL SR  ++
Sbjct: 2176 HAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAA 2235

Query: 980  SHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFP 1039
            S    + +++RT  P  P A      +   S+ P A    +  +PR +  P  +      
Sbjct: 2236 SAAAMNLASART--PAIPTA-----VNLADSRTPAAAAAMNLASPRTAVAPSAVN----- 2283

Query: 1040 FFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQ 1099
               +PR P +           PAV +     P A +    T     P   +   +    Q
Sbjct: 2284 -LADPRTPTA-----------PAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQ 2331

Query: 1100 SPQHEPLQLP------APVCI-GYRD----APRASSPPRQAP--------EPSLLFQDLP 1140
            +P    L  P      APV I G R     AP + +  R AP         P +      
Sbjct: 2332 APASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYE 2391

Query: 1141 RASTESLVPSMDSLHE--CPHIPTPVCIGHRDAPSFSSPPRQAPEPSLF--FQDPPGTSM 1196
            R S  +  P +D       P  P+   +    APS SS   QAP  SL    QD P + +
Sbjct: 2392 RVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPV 2451

Query: 1197 ES--------------------------LAPSTDSL--HGSPVLIPQVCIGHRDA--PRA 1226
             S                          +A +T S   H   + +P   + H D   P A
Sbjct: 2452 PSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPA 2511

Query: 1227 SSPPRHPPSDLAFLAP--------------SPSPGSSGGSRGSAPPGETRHNLEREEYTV 1272
            S+  +  PS LA L P              S S  SS  S  S+  G +  + E     V
Sbjct: 2512 STGAQQ-PSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPV 2570

Query: 1273 LADLPPPRRLAQRQPGPQAQCSSGGRTHSPGRAEVERLFGQERRKSEAAGAFQAQDEGRS 1332
              ++   +R+    P P+ +    GR   P  A+      ++RR S ++ +  +     S
Sbjct: 2571 QPEV-ALKRVPSPTPAPK-EAVREGRPPEPTPAK------RKRRSSSSSSSSSSSSSSSS 2622

Query: 1333 QQPSQGQSQLLRRQSSPAPSRQVTMLPAKQAELTRRSQAEPPHPWSPEKRPEGDRQLQGS 1392
               S   S      SS + S   +  P+      +      P P SP+K P G+R+ + S
Sbjct: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSPSP----AKPGPQALPKPASPKKPPPGERRSR-S 2677

Query: 1393 PLPPRTSARTPERELRTQRPLESGQAGPRQPLGVWQSQEEPPGSQGPHRHLERS 1446
            P  P  S R  +    +  P+E  +  P+      QS     GS+   R   RS
Sbjct: 2678 PRKPIDSLR--DSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRS 2729



 Score =  167 bits (424), Expect = 9e-41
 Identities = 435/2032 (21%), Positives = 702/2032 (34%), Gaps = 312/2032 (15%)

Query: 176  RRPREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLER 235
            ++P   P    S    S  +RSP       +KK+D G    S+     R +       ++
Sbjct: 161  KQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKK---KK 217

Query: 236  HRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASST 295
            HRS     S    H  P   + + S  ++   ++ ST   P++   HR T  D++ +S T
Sbjct: 218  HRSE--SESKKRKHRSPTPKSKRKSKDKK-RKRSRSTTPAPKSRRAHRSTSADSASSSDT 274

Query: 296  QQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPR 355
             +  SR+++ +  T+  +            + D P +     +T R SSP  +T+  +  
Sbjct: 275  SRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSP 334

Query: 356  TSSTQQDNPQTSF--PTCTPQREN----PRTPCVQQDDPRASSPNRTTQRENSRTSCAQR 409
                 +D  + S   P+ +P+R +    P  P     +    SP        S+      
Sbjct: 335  YEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPP 394

Query: 410  DNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASR---- 465
                 +R  SP ++    P++S ++  +P +  P++ +R   ++  + +  P        
Sbjct: 395  SEASPTRDRSPPKSPEKLPQSSSSE-SSPPSPQPTKVSRHASSSPESPKPAPAPGSHREI 453

Query: 466  TSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDN 525
            +SSP    R + R   A+RD   + +PSR                R  R+ SP  A R  
Sbjct: 454  SSSPTSKNRSHGR---AKRDKSHSHTPSR----------------RMGRSRSPATAKRGR 494

Query: 526  PRT-SCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDN 584
             R+ +  +R + R+ SP      +       R   R  R+ SP R      R +  +R  
Sbjct: 495  SRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNT-QRRGR 553

Query: 585  PRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQ 644
             R++   R+   +P T          SR+ +P R  R   RT   +R   R+ +P R   
Sbjct: 554  SRSARRGRSHSRSPATR-------GRSRSRTPARRGRSRSRTPARRRS--RSRTPTR--- 601

Query: 645  QDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRD 704
                R S +R    R  S +RT  +   RT   +R   R+ SP+R   +   RT  A+R 
Sbjct: 602  ----RRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTP-ARRG 656

Query: 705  DPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQ 764
              R+ +P             ARR   R+ +  R   R   RT  A+R   R+ +P R   
Sbjct: 657  RSRSRTP-------------ARRGRSRSRTPARRSGRSRSRTP-ARRGRSRSRTPRRGRS 702

Query: 765  QENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIP 824
            +     S  R+    + +P R  R     S ++R N   +S  R+    +P    +  I 
Sbjct: 703  RSR---SLVRRGRSHSRTPQRRGRSG---SSSERKNKSRTSQRRSRSNSSPE-MKKSRIS 755

Query: 825  RSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPH 884
               S    +P++    R +LR +                  + SS C  QK    P    
Sbjct: 756  SRRSRSLSSPRSKAKSRLSLRRSL-----------------SGSSPCPKQKSQTPPRRSR 798

Query: 885  RSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQG 944
              +     ++ +P R ++    +S P  P +      S  S S  S  P       P QG
Sbjct: 799  SGSSQPKAKSRTPPRRSRS---SSSP--PPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQG 853

Query: 945  D--RPQTSSPSRPAQH--------DPPQSSFGPTQYNL----PSRATSSSHNPGHQSTSR 990
                PQ +  S   Q         DP   S  P++++     P R  SS+  P  QS SR
Sbjct: 854  SITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSST--PPRQSPSR 911

Query: 991  TSS--PVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRAS---SPPRYLQHDPFPFFPE-- 1043
            +SS  P   A       S   S  P    +  R  PR S   SP   ++    P +    
Sbjct: 912  SSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSG 971

Query: 1044 PRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQC-QSPQ 1102
              +P+++     PP    +  I      +A +PP           P  S ++  C Q   
Sbjct: 972  SSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPG----------PSLSGSKSPCPQEKS 1021

Query: 1103 HEPLQLPAPVCIGYRDAPRASSPPRQA--PEPSLLFQDLPRASTESLVPSMDSLHECPHI 1160
             + L    P  +      ++S+PP ++     SL  +   + S +         H     
Sbjct: 1022 KDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPD---------HRSDTS 1072

Query: 1161 PTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLAP---STDSLHGSPVLIPQVC 1217
               V   H ++PS  S  + +P+        P T + S +P          SP+L  +  
Sbjct: 1073 SPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPML--KSG 1130

Query: 1218 IGHRDAPRASSPPRHPPSDL-AFLAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVLADL 1276
            +    +   S    +P  D  + L  S    +    + + PP E             A  
Sbjct: 1131 MSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQED------------ATA 1178

Query: 1277 PPPRRLAQRQPGPQAQCSSGGRTHSPGRAEVERLFGQ----ERRKSEAAGAFQAQDEGRS 1332
             PPR+  +  P P              R E   +F        R+   AG+     E  S
Sbjct: 1179 SPPRQKDKFSPFPVQD-----------RPESSLVFKDTLRTPPRERSGAGSSPETKEQNS 1227

Query: 1333 QQPSQGQSQLLRR--QSSPAPSRQVTMLPAKQAELTRRSQAEPPHPWSPEKRP------- 1383
              P+  Q + L    + S  P+ Q+  L    +EL   S +        E+RP       
Sbjct: 1228 ALPTSSQDEELMEVVEKSEEPAGQI--LSHLSSELKEMSTSNFESSPEVEERPAVSLTLD 1285

Query: 1384 --EGDRQLQGSPLPPRTS--------------ARTPERELRTQRPLESGQAGP------- 1420
              +    L+   +P   S              + +P RE     PLE   +GP       
Sbjct: 1286 QSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNT 1345

Query: 1421 ------RQPL-GVWQSQEEPPGSQGPHRHLERSWSSQEGGLGPGGWWGCGEPSLGAAKAP 1473
                  ++ L G + +Q E   S        RS       L P      G  S  +  +P
Sbjct: 1346 GFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSP 1405

Query: 1474 --EGAWGGTSREYKESWGQPEAWEEKPTHELPRELGKRSPLTSPP---ENWGGPAESSQS 1528
              +      SRE   S   PE  +      LPR   +RS   S P   +  G P+  S S
Sbjct: 1406 VLDAVPRTPSRERSSSASSPEMKD-----GLPRTPSRRSRSGSSPGLRDGSGTPSRHSLS 1460

Query: 1529 WHS-------GTPTAVGWGAEGACPYPRGSERRPELDWRDLLGLLRAPGEGVWARVPSLD 1581
              S        TP+  G     + P P+   + P    R       +P        P  +
Sbjct: 1461 GSSPGMKDIPRTPSR-GRSECDSSPEPKALPQTPRPRSRS----PSSPELNNKCLTPQRE 1515

Query: 1582 WEGLLELLQARLPRKDPAGHRDDLARALGPELGPPGTNDVPEQESHSQPEGWAEA-TPV- 1639
              G    +  +   + P G R     +   ++  P  +     ES S P+  A+  TP+ 
Sbjct: 1516 RSGSESSVDQKTVARTPLGQRSRSGSSQELDV-KPSASPQERSESDSSPDSKAKTRTPLR 1574

Query: 1640 ----NGHSPALQSQSPVQLPSPACTSTQWPKIKVTRGPATATLAG--------------L 1681
                +G SP + S+S  +L      S   P++K     A    +G              L
Sbjct: 1575 QRSRSGSSPEVDSKS--RLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRAL 1632

Query: 1682 EQTGPLGSRSTAKGPSLPE----LQFQPEEPEESEPS-RGQDPLTDQKQADSADKRPAEG 1736
             +    GS S  +GPS PE     +  PE P +S  + RG     + K       R    
Sbjct: 1633 PRRSRSGSSSKGRGPS-PEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSS 1691

Query: 1737 KAGSPLKGRLVTSWRMPGDRPTLFNPFLLSLGVLRWRRPDLLNFKKGWMSILDEPGE--- 1793
            ++   L  +   S R    R    +P   S    R RR   ++          EP E   
Sbjct: 1692 RSSPELTRKARLSRR---SRSASSSPETRSRTPPRHRRSPSVS--------SPEPAEKSR 1740

Query: 1794 -------PPSPSLTTTS----TSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDL--- 1839
                     SP   TTS    +   K      + S  +  +  T    D           
Sbjct: 1741 SSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRR 1800

Query: 1840 ----RSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIE----ALRKTVRPTSA 1891
                RS + VT    +R  G   H++      S+ TS  RR          RK  R  ++
Sbjct: 1801 RQRSRSRSRVTR---RRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTS 1857

Query: 1892 PDVTKLSDSNKENALHSYSTQKGPL-KAGEQRAGSEVISRGGPRKADGQRQALDYVELSP 1950
            P   K S S    A H  S  + PL      R+ +  +SR   R      +       SP
Sbjct: 1858 PAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASP 1917

Query: 1951 LTQASPQRARTPARTPDRLAKQEELERDLAQRSEERRKWFEATDSRTPEVPAGEGPRRGL 2010
            +++    R+RTP  T  R   +    R   +RS  R        SR+   P      R  
Sbjct: 1918 VSRRR-SRSRTPPVTRRRSRSRTPTTR---RRSRSRTPPVTRRRSRSRTPPVTRRRSRSR 1973

Query: 2011 GAPLTEDQQNRLSEEIEKKWQELEKLPLRENKRVPLTALLNQSRGERRGPPS 2062
             +P+T  +    +  + ++       P+   +    T+ + + R   R PP+
Sbjct: 1974 TSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPA 2025



 Score =  124 bits (310), Expect = 1e-27
 Identities = 360/1630 (22%), Positives = 557/1630 (34%), Gaps = 286/1630 (17%)

Query: 38   QELRSPSGAEVPYCDLPRCPPAPEDPLSASTSGCQSVVDP----------GLRPGPKRGP 87
            QE  +P     P  D  R PP   + L  S+S   S   P               PK  P
Sbjct: 388  QEPVNPPSEASPTRD--RSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAP 445

Query: 88   SPSAGLP-EEGPTAAPRSRSRELEAVPYLEGLTTSLCGSCNEDPGSDPTSSPDSATPDDT 146
            +P +       PT+  RS  R      +    T S     +  P +       S TP   
Sbjct: 446  APGSHREISSSPTSKNRSHGRAKRDKSHSH--TPSRRMGRSRSPATAKRGRSRSRTPTKR 503

Query: 147  SNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAGQ 206
             +S S            +P W        RR R   R   S R+P    RS         
Sbjct: 504  GHSRS-----------RSPQW--------RRSRSAQRWGRS-RSPQRRGRSRSPQRPGWS 543

Query: 207  KKEDTGGGGRSAGQHWARLRGESGLSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDT 266
            +  +T   GRS        RG S       RS  T+  S +     R  +   +PA+R +
Sbjct: 544  RSRNTQRRGRSRSAR----RGRS-----HSRSPATRGRSRSRTPARRGRSRSRTPARRRS 594

Query: 267  AQAASTREIPRASSPHRI----TQRDTSRASSTQQEISRASSTQQETSRASSTQEDTP-- 320
                 TR   R+ +P R     ++    R S T+  + R S ++    R+  ++  TP  
Sbjct: 595  RSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPAR 654

Query: 321  RASSTQEDTPRASSTQWNTP-RASSPSRS-TQLDNPRTSS-TQQDNPQTSFPTCTPQREN 377
            R  S      R   ++  TP R S  SRS T     R+ S T +     S       R +
Sbjct: 655  RGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSH 714

Query: 378  PRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNP--KASRTSSPNRATRDNPRTSCAQR 435
             RTP  Q+     SS  R  +   S+       +P  K SR SS    +  +PR+    R
Sbjct: 715  SRTP--QRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR 772

Query: 436  DNPRASSPSRATRDNPTTSCAQRDNPRASRTSS--PNRATRDNPRTSCAQRDNP---RAS 490
             + R S     +  +P      +  PR SR+ S  P   +R  PR S +    P   ++ 
Sbjct: 773  LSLRRS----LSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSK 828

Query: 491  SPSRATRDN--PTTSCAQRDNPRASRTSSP--NRATRDNPRTSCAQRDNPRASSPNRAAR 546
            +PSR +  +  P         PR    +SP  N  +    R SC +     +  P   +R
Sbjct: 829  TPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFES----SPDPELKSR 884

Query: 547  DNPTTSCAQRDNPRASRTS----SPNRATRDNPRT----SCAQRDNPRASSPN------- 591
                 SC+    PR   ++    SP+R++   P+     S  QR +  +SSP+       
Sbjct: 885  TPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSR 944

Query: 592  ----RATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDS 647
                R+   +P ++   R  PR S + S +  T+  P T   Q  +   S   +   Q  
Sbjct: 945  TTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTP 1004

Query: 648  PRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSP----------------SRTI 691
            P  S +    P     ++    ++   S +L    ++S+P                S+T 
Sbjct: 1005 PGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTS 1064

Query: 692  QQENPRTSCAQRDDPRASSPN-RTTQQENPRTSCARRDNPRASSRNRT-IQRD------- 742
                  TS  +     + SP+ ++  Q +P+   +R  +P     +R+ I++D       
Sbjct: 1065 PDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSAS 1124

Query: 743  -------NPRTSCAQRDN---PRASSPNRTIQQENLRTSCTRQ------DNPRTSSPNR- 785
                   +P  S  Q D+   P   S N  + Q  L T+ +++          T+SP R 
Sbjct: 1125 PMLKSGMSPEQSRFQSDSSSYPTVDS-NSLLGQSRLETAESKEKMALPPQEDATASPPRQ 1183

Query: 786  -------ATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQN-IPRSSSTQQ------ 831
                     +D P +S   +D LR     R+    +P T  Q + +P SS  ++      
Sbjct: 1184 KDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVE 1243

Query: 832  --DNPKTSCTKR--DNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRST 887
              + P           L+   T    +     +R     +  Q  +Q        P  ++
Sbjct: 1244 KSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMAS 1303

Query: 888  QWNNPRNSSPHRTNKDIPWASFPLRPTQSDGP---RTSSPSRSKQSEVPWASIALRPTQG 944
             W  P  S  H+       ++ PLR      P   R S P  ++ +   ++S       G
Sbjct: 1304 SWGGPHFSPEHK-----ELSNSPLRENSFGSPLEFRNSGPLGTEMN-TGFSSEVKEDLNG 1357

Query: 945  DRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPL 1004
              P  +        D  + S   + ++    +  +    G  S    SSPV  A    P 
Sbjct: 1358 --PFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPS 1415

Query: 1005 TSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESEPPHHEPPYIPPAVC 1064
                 S               ASSP      D  P  P  R+     P            
Sbjct: 1416 RERSSS---------------ASSPE---MKDGLPRTPSRRSRSGSSP------------ 1445

Query: 1065 IGHRDAPRASSPPRHTQFDPFPFLPD----TSDAEHQCQSPQHEPLQLPAPVCIGYRDAP 1120
             G RD   + +P RH+     P + D     S    +C S        P P  +     P
Sbjct: 1446 -GLRDG--SGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSS-------PEPKALPQTPRP 1495

Query: 1121 RASSPPRQAPEPSLLFQDLPRASTESLVPS-------------MDSLHECPHIPTPVCIG 1167
            R+ SP         L     R+ +ES V                 S  E      P    
Sbjct: 1496 RSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELD--VKPSASP 1553

Query: 1168 HRDAPSFSSPPRQAP------EPSLFFQDPPGTSMESLAPSTDSLHGSPVLIPQVCIGHR 1221
               + S SSP  +A       + S     P   S   L+P       S    P+V    R
Sbjct: 1554 QERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSS----PEVKDKPR 1609

Query: 1222 DAPRA-----SSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVLADL 1276
             APRA     SSP    P+  A    S S GSS   RG +P G +      E        
Sbjct: 1610 AAPRAQSGSDSSPEPKAPAPRALPRRSRS-GSSSKGRGPSPEGSSSTESSPEH------- 1661

Query: 1277 PPPRRLAQRQPGPQAQCSSGGRTHSPGRAEVERLFGQERRK---SEAAGAFQAQDEGRSQ 1333
            PP  R A+R  G ++      ++ +P R    R   +  RK   S  + +  +  E RS+
Sbjct: 1662 PPKSRTARR--GSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSR 1719

Query: 1334 QPSQGQSQLLRRQSSPAPSRQVTMLPAKQAELTRRSQAEPPHPWSPEKRPEGDRQLQGSP 1393
             P        R + SP+ S   +  PA+++  +RR ++      SP  +    R    SP
Sbjct: 1720 TPP-------RHRRSPSVS---SPEPAEKSRSSRRRRSAS----SPRTKTTSRRGRSPSP 1765

Query: 1394 LP---PRTSARTPERELRTQRPLE---SGQAGPRQPLGVWQSQEEPPGSQGPHRHLERSW 1447
             P    R+ +R+   + RT R  +   S Q+  R+              +G   +  RS 
Sbjct: 1766 KPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSP 1825

Query: 1448 SSQEGGLGPGGWWGCGEPSLGAAKAPEGAWGGTSREYKESWGQPEAWEEKPTHELP---R 1504
            + QE                G ++ P      TSR+   S   P  W+   +   P   R
Sbjct: 1826 ARQESSR------TSSRRRRGRSRTPP-----TSRKRSRSRTSPAPWKRSRSRASPATHR 1874

Query: 1505 ELGKRSPLTS 1514
                R+PL S
Sbjct: 1875 RSRSRTPLIS 1884



 Score =  114 bits (286), Expect = 9e-25
 Identities = 266/1142 (23%), Positives = 403/1142 (35%), Gaps = 194/1142 (16%)

Query: 20   QNRCQNCFHPEEAHGARYQELRSPSGAEVPYCDLPRCPPAPEDPLSASTSGCQSVVDPGL 79
            + R ++   PE    +R    RS SG+     D PR  P  +       SG  S  +P  
Sbjct: 1574 RQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQ-------SGSDSSPEPKA 1626

Query: 80   RPGPK--------------RGPSPS-AGLPEEGPTAAPRSRSRELEAVPYLEGLTTSLCG 124
             P P+              RGPSP  +   E  P   P+SR+    +    E  T S   
Sbjct: 1627 -PAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTP 1685

Query: 125  SCNEDPGSDP---------------TSSPD--SATPDDTSNSSSVDWDTVERQEEEAPSW 167
                   S P               +SSP+  S TP     S SV   + E  E+   S 
Sbjct: 1686 PRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVS--SPEPAEKSRSSR 1743

Query: 168  DELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRG 227
               +   PR      R  S    P  L RS      +  ++E T    R       R R 
Sbjct: 1744 RRRSASSPRTKTTSRRGRSPSPKPRGLQRS-----RSRSRREKTRTTRR-------RDRS 1791

Query: 228  ESGLSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQR 287
             S  S  R R      S +T      S     SPA++++++ +S R   R+ +P    +R
Sbjct: 1792 GSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKR 1851

Query: 288  DTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTP---RASSTQWNTPRASS 344
              SR S    + SR+ ++     R+ S      R  S    +P   R S ++ +  R  S
Sbjct: 1852 SRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRS 1911

Query: 345  PSRSTQLDNPRTSS----TQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRE 400
             SR++ +   R+ S      +   ++  PT T +R   RTP V +   R+ +P  T +R 
Sbjct: 1912 RSRASPVSRRRSRSRTPPVTRRRSRSRTPT-TRRRSRSRTPPVTRRRSRSRTPPVTRRRS 1970

Query: 401  NSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRA-SSPSRATRDNPTTSCAQRD 459
             SRTS   R   + SRTS   R  R   RTS   R   R+ +SP    R    T  A R 
Sbjct: 1971 RSRTSPITRRRSR-SRTSPVTRR-RSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRR 2028

Query: 460  NPRA---------SRTSSP----NRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQ 506
              R+         SR+ SP     R+    PRT+  +R   R  SP    R + + S + 
Sbjct: 2029 RSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTR--SPPAIRRRSASGSSSD 2086

Query: 507  RDN---PRASRTSSPNRA---TRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPR 560
            R     P A+R  S +R      ++ R SC  R +   +  +R               P 
Sbjct: 2087 RSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPM 2146

Query: 561  A-------SRTSSPNRATRDNPRTSCAQ-------------------RDNPRASSPNRAT 594
            +       S    P     D+ RTS  +                   R  P  S+   A 
Sbjct: 2147 SVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAA 2206

Query: 595  RDN----PTTSCAQRDNPRASRTS--------SPNRATRDNPRTSCA-----QRDNPRAS 637
            R +    P    + R  P A+  S        + N A+   P    A      R    A+
Sbjct: 2207 RMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAA 2266

Query: 638  SPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALR--------DNPRAS---S 686
            + N  + + +   S     DPR  +    +     RT  AL           P A+   S
Sbjct: 2267 AMNLASPRTAVAPSAVNLADPRTPTAP-AVNLAGARTPAALAALSLTGSGTPPTAANYPS 2325

Query: 687  PSRTIQQE------NPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRT-- 738
             SRT Q         PR++ A    P   + +RT     P +  + R  P  S  N T  
Sbjct: 2326 SSRTPQAPASANLVGPRSAHATA--PVNIAGSRTAAALAPASLTSARMAPALSGANLTSP 2383

Query: 739  ------IQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPR 792
                   +R + RTS    D  R+ +P     Q       +R  + R  SP+      P 
Sbjct: 2384 RVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQ-------SRMTSERAPSPSSRMGQAPS 2436

Query: 793  TSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRD 852
             S       +  SP+ +   D  R  I Q  P + S    +   + T       T +  D
Sbjct: 2437 QSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATT-------TSSAGD 2489

Query: 853  RTQSFSFQR---------DNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKD 903
                 S            + P ++ +Q  +    L+P+   RS+  ++  +SS   ++  
Sbjct: 2490 HNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSS 2549

Query: 904  IPWASFPLRPTQSDGPRTSSPSRSK------QSEVPWASIALR------PTQGDRPQTSS 951
               +S     + SD   +S P + +       S  P    A+R      PT   R + SS
Sbjct: 2550 SS-SSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSS 2608

Query: 952  PSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQ 1011
             S  +      SS   +  +  S ++SSS +    S+S + SP  P     P  +  P +
Sbjct: 2609 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPA-SPKK 2667

Query: 1012 PP 1013
            PP
Sbjct: 2668 PP 2669



 Score = 69.3 bits (168), Expect = 4e-11
 Identities = 104/467 (22%), Positives = 176/467 (37%), Gaps = 52/467 (11%)

Query: 186  SSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRSTLTQASS 245
            SS R P    ++P   +  G +          AG   A     + L+  R    L+ A+ 
Sbjct: 2325 SSSRTP----QAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANL 2380

Query: 246  MTPH---SGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEISRA 302
             +P    S     + + SP   D A++   R  P A S  R+T   + RA S    + +A
Sbjct: 2381 TSPRVPLSAYERVSGRTSPPLLDRARS---RTPPSAPSQSRMT---SERAPSPSSRMGQA 2434

Query: 303  SSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQD 362
             S           +   P A S Q     A +T    P A S S S+      TSS    
Sbjct: 2435 PSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTT----PVAGSQSLSSGAVATTTSSAGDH 2490

Query: 363  NPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSSPNR 422
            N   S P        P  P     +P AS    T  ++ S  +  Q    + S +SS + 
Sbjct: 2491 NGMLSVPA-------PGVPHSDVGEPPAS----TGAQQPSALAALQPAKERRSSSSSSSS 2539

Query: 423  ATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCA 482
            ++  +  +S +   +   SS S    D+  +S   +      R  SP  A ++  R    
Sbjct: 2540 SSSSSSSSSSSSSSSSSGSSSS----DSEGSSLPVQPEVALKRVPSPTPAPKEAVREG-- 2593

Query: 483  QRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPN 542
                P   +P++  R + ++S +   +  +S +SS + ++  +  +S +   +  +SSP+
Sbjct: 2594 ---RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650

Query: 543  RAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSC 602
              A+  P         P + +   P      +PR       + R+ S +   R  P+   
Sbjct: 2651 -PAKPGPQAL----PKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQP 2705

Query: 603  AQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPR 649
                +PR  ++SS  R +R        QR + R+ S  R  +  SPR
Sbjct: 2706 ----SPRDQQSSSSERGSRR------GQRGDSRSPSHKRRRETPSPR 2742



 Score = 35.0 bits (79), Expect = 0.87
 Identities = 32/149 (21%), Positives = 57/149 (38%), Gaps = 4/149 (2%)

Query: 1948 LSPLTQASPQRARTPARTPDRLAKQEELERDLAQRSEERRKWFEATDSRTPEVPAGEGPR 2007
            ++P ++ASP R R+P ++P++L +    E         +     ++   +P+     G  
Sbjct: 391  VNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSH 450

Query: 2008 RGLGAPLTEDQQNRLSEEIEKKWQELEKLPLRENKRVPLTALLNQSRGERRGPPSDGHEA 2067
            R + +  T   +NR S    K+ +     P R   R    A   + R   R P   GH  
Sbjct: 451  REISSSPT--SKNR-SHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSR 507

Query: 2068 LEKEVQALRAQLEAWRLQGEAPQSALRSQ 2096
                        + W  +  +PQ   RS+
Sbjct: 508  SRSPQWRRSRSAQRWG-RSRSPQRRGRSR 535



 Score = 31.6 bits (70), Expect = 9.7
 Identities = 33/137 (24%), Positives = 53/137 (38%), Gaps = 19/137 (13%)

Query: 1296 GGRTHSPGR----AEVERLFGQERRKSE----AAGAFQAQDEGRSQQPSQGQSQLLRRQS 1347
            GG+  +PG+     E  +L     +K+E    A G   +  +G S  P +      R   
Sbjct: 106  GGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRA----REAK 161

Query: 1348 SPAPSRQVTMLPAKQAELTRRSQAE-PPHPWSPEKRPEGDRQLQGSPLPPRTSARTPERE 1406
             PAP       P K   L R S +   P P   +K+ + DR  +     PR   +   ++
Sbjct: 162  QPAPE------PPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKK 215

Query: 1407 LRTQRPLESGQAGPRQP 1423
             + +   ES +   R P
Sbjct: 216  KKHRSESESKKRKHRSP 232


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score =  155 bits (392), Expect = 4e-37
 Identities = 175/673 (26%), Positives = 286/673 (42%), Gaps = 73/673 (10%)

Query: 223 ARLRGESGLSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPH 282
           ++ R  S +S +   S  ++AS +  H    + +   +P +R +   +S R   RAS+P 
Sbjct: 86  SKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSR--SSKRSPSRASTPG 143

Query: 283 RITQRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPR-ASSTQWNTPR 341
           RI    T  A        R  ++QQ+ SR  S            +  PR  S   +  P 
Sbjct: 144 RIR---THGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPG 200

Query: 342 ASSPSRSTQLD-NPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRE 400
            S   RS++L   P T+  Q        PT  P +E       + D+P  SS  +     
Sbjct: 201 GSGIGRSSELAVTPSTAKCQT-------PTGIPSKE-------KSDNPSPSSSRKVK--- 243

Query: 401 NSRTSCAQRDNPKASRTSSPNR-ATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRD 459
               S  Q   P   ++ SP   ++R       + R  P++ S SR+             
Sbjct: 244 ----SYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRS------------- 286

Query: 460 NPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRAT------RDNPTTSCAQRDNPRAS 513
            PR SR+ S  R T    R+   +R++ RA S +R        R + + S ++  +   S
Sbjct: 287 -PRRSRSGSQKR-THSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQS 344

Query: 514 RTSSPNRA-----------TRDNPRTSCAQRDNPRASSPNR-AARDNPTTSCAQRDNPRA 561
           RT    R+           +  + R+S  +RD+  +SSP + + R    +   QRD+   
Sbjct: 345 RTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDH--- 401

Query: 562 SRTSSPNRAT-RDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRAT 620
           SR+ SPN+A  R   R+    RD  R+ SPN+A RD   +    +   R SR+ SPN+A 
Sbjct: 402 SRSRSPNKARDRSRSRSPYKARDRSRSRSPNKA-RDCSRSRSPYKARDR-SRSRSPNKA- 458

Query: 621 RDNPRTSCAQ--RDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCAL 678
           RD+ R+      RD  R+ SP++        +    RD  R+ SP++  Q    R+S   
Sbjct: 459 RDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKE 518

Query: 679 RDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRT 738
           RD+ R+ SPS+  Q+   R+   +RD  ++ SP+   +    R+    RD  R  S ++ 
Sbjct: 519 RDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKE 578

Query: 739 IQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNR-ATRDNPRTSCAQ 797
            +R   R+S  +RD+ R+ SPN+       R S   + + R+ +P++       RTS  +
Sbjct: 579 RERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKE 638

Query: 798 RDNLRASSPIRATQQDNP-RTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQS 856
            D  +++ P     + +P RT         S T   +P T  +    L    +Q D T S
Sbjct: 639 SDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTS 698

Query: 857 FSFQRDNPGTSSS 869
            +       +SSS
Sbjct: 699 KATLPGERSSSSS 711



 Score =  151 bits (382), Expect = 6e-36
 Identities = 182/751 (24%), Positives = 303/751 (40%), Gaps = 108/751 (14%)

Query: 343  SSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRT---TQR 399
            SSP RS++   P  S     +   S PT  P+      P       ++++PNR+   T+ 
Sbjct: 2    SSPKRSSK---PSMSLAPSGS---SMPTADPK------PPASLKSTKSATPNRSLVPTKP 49

Query: 400  ENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRD 459
              SR S     + K+++++S  RA  + P  S   R   +A +PSR + D  T+  ++  
Sbjct: 50   ATSRNSVMSPSSSKSTKSTSTKRAPSNRP--SSRSRVRSKARTPSRVSTDTRTSKASKAS 107

Query: 460  NPRA-SRTSSPNRATRDNPRTSCAQRDNP-RASSPSRATRDNPTTSCAQRDNPRASRTSS 517
            + R   R  + +R      R S + + +P RAS+P R          A R     S+   
Sbjct: 108  DVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKG 167

Query: 518  PNRATRDNPRTSCAQRDN-------------PRASSPNRAARDNPTTSCAQRDNPRASRT 564
                +   PRTS  +R +             P  S   R++    T S A+   P    T
Sbjct: 168  SRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTP----T 223

Query: 565  SSPNRATRDNPRTSCAQRD--------------------NPRASSPNRATRDNPTTSCAQ 604
              P++   DNP  S +++                     + R  S N+A+  +   S +Q
Sbjct: 224  GIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQ 283

Query: 605  RDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRT------------------TQQD 646
              +PR SR+ S  R T    R+   +R++ RA S  R                     Q+
Sbjct: 284  SRSPRRSRSGSQKR-THSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQN 342

Query: 647  SPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDP 706
              RT    R    + +P++     + R+S   RD+  +SSP +   +    +   QRD  
Sbjct: 343  QSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHS 402

Query: 707  RASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQE 766
            R+ SPN+   +   R+    RD  R+ S N+       R+    RD  R+ SPN+     
Sbjct: 403  RSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHS 462

Query: 767  NLRTSCTRQDNPRTSSPNRATRDNPR--TSCAQRDNLRASSPIRATQQDNPRTCIQQNIP 824
              R+    +D  R+ SP++  RD+ +  +   +RD+ R+ SP +  Q      C Q    
Sbjct: 463  RSRSPNKARDRSRSRSPSKE-RDHSQLGSPSKERDHRRSRSPSKERQ------CRQS--- 512

Query: 825  RSSSTQQDNPKTSCTKRDNLRPTCT----QRDRTQSFSFQRDNPGTSSSQCCTQKENLRP 880
            RSSS ++D+ ++    ++  R        +RDR+QS S   +     S     +++  R 
Sbjct: 513  RSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRW 572

Query: 881  SSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRS-KQSEVPWASIAL 939
             SP +  +    R+SS  R   D   +  P + +    PR SS  ++  +S  P      
Sbjct: 573  RSPSKERERRQSRSSSEER---DHSRSRSPNKQSGYSRPRASSKEKAHSRSRTP------ 623

Query: 940  RPTQGDRPQTSSPSRPAQHDPPQSSF--GPTQYNLPSRATSSSHNPGHQSTSRTSSPVYP 997
               +G+  Q+ + S+  + DP QS+    P     P+R +S S N     TS  S   +P
Sbjct: 624  -SKEGNHSQSRTSSK--ESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFP 680

Query: 998  AAYGAPLTSPEPSQPPCAVCIGHRDAPRASS 1028
            +  G    S + SQ             R+SS
Sbjct: 681  S--GGQTLSQDDSQADATTSKATLPGERSSS 709



 Score =  151 bits (381), Expect = 8e-36
 Identities = 175/740 (23%), Positives = 305/740 (41%), Gaps = 80/740 (10%)

Query: 304 STQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQDN 363
           S+ + +S+ S +   +  +  T +  P AS     + ++++P+RS     P TS     +
Sbjct: 2   SSPKRSSKPSMSLAPSGSSMPTADPKPPASL---KSTKSATPNRSLVPTKPATSRNSVMS 58

Query: 364 PQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSS---- 419
           P +S  T     ++  T     + P + S  R+  R  SR S   R + KAS+ S     
Sbjct: 59  PSSSKST-----KSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTS-KASKASDVRCH 112

Query: 420 PNRATRDNPRTS------CAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRAT 473
             R T    RT        ++R   RAS+P R          A R     S+       +
Sbjct: 113 QRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKS 172

Query: 474 RDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRA---------SRTSSPNRATRD 524
              PRTS  +R + +  + S+ +   P  S   R +  A         + T  P++   D
Sbjct: 173 YGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSD 232

Query: 525 NPRTSCAQRD--------------------NPRASSPNRAARDNPTTSCAQRDNPRASRT 564
           NP  S +++                     + R  S N+A+  +   S +Q  +PR SR+
Sbjct: 233 NPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRS 292

Query: 565 SSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNP 624
            S  R T    R+   +R++ RA S  R          +Q      SR+ S  ++ ++  
Sbjct: 293 GSQKR-THSRVRSHSWKRNHSRARSRTRKG------ILSQMGRHSQSRSHSKGKS-QNQS 344

Query: 625 RTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRA 684
           RT    R +  + +P++       R+S   RD   +SSP +   +    +    RD+ R+
Sbjct: 345 RTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRS 404

Query: 685 SSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNP 744
            SP++   +   R+    RD  R+ SPN+       R+    RD  R+ S N+       
Sbjct: 405 RSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRS 464

Query: 745 RTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATR-DNPRTSCAQRDNLRA 803
           R+    RD  R+ SP++      L +    +D+ R+ SP++  +    R+S  +RD+ R+
Sbjct: 465 RSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRS 524

Query: 804 SSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDN 863
            SP +  Q+   R+    N  R  S Q  +P      R +  P+  +RDR +  S  ++ 
Sbjct: 525 RSPSKERQRRQSRS---PNKERDRS-QSRSPSEEREHRQSRSPS-KERDRRRWRSPSKER 579

Query: 864 PGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSS 923
               S     ++++ R  SP++ + ++ PR SS  +       A    R    +G  + S
Sbjct: 580 ERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEK-------AHSRSRTPSKEGNHSQS 632

Query: 924 PSRSKQSEVPWASIALRPTQGDRP-------QTSSPSRPAQHDPPQ-SSFGPTQYNLPSR 975
            + SK+S+   +++   P     P       Q  +PS+ + H P    S G T     S+
Sbjct: 633 RTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQ 692

Query: 976 A---TSSSHNPGHQSTSRTS 992
           A   TS +  PG +S+S +S
Sbjct: 693 ADATTSKATLPGERSSSSSS 712



 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 130/526 (24%), Positives = 212/526 (40%), Gaps = 77/526 (14%)

Query: 64  LSASTSGCQSVVD-PGLRPGPKRGPSPSAGLPEEGPTAAPRSRSRELEAVPYLEGLTTSL 122
           ++ ST+ CQ+    P         PS S  +   G    P   SRE    P      T +
Sbjct: 212 VTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIP---SREKSYSP------TEM 262

Query: 123 CGSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGP 182
                    +   S P S +   +   S             + SW         R R+G 
Sbjct: 263 SSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGI 322

Query: 183 RADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRSTLTQ 242
            +   + + S   RS   G +  Q +  T   GRS   +W+R       S ER  S    
Sbjct: 323 LSQMGRHSQS---RSHSKGKSQNQSR--TPRRGRS--HNWSR-----NPSKERSHSHSRS 370

Query: 243 ASSMTPHSGPRSTTSQASPAQ-------RDTAQAAS---TREIPRASSPHRITQRDTSRA 292
           +S    H G  S   ++  +Q       RD +++ S    R+  R+ SP++   R  SR+
Sbjct: 371 SSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRS 430

Query: 293 SSTQQEISRASST----QQETSRASSTQEDTPRASSTQEDTPRASS---------TQWNT 339
            +  ++ SR+ S      +  SR+ +   D  R+ S  +   R+ S         +Q  +
Sbjct: 431 PNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGS 490

Query: 340 P-------RASSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASS 392
           P       R+ SPS+  Q    R+SS ++D+ ++  P+   QR   R+P  ++D  ++ S
Sbjct: 491 PSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRS 550

Query: 393 PNRTTQRENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDN--------------P 438
           P+   +   SR+   +RD  +  R+ S  R  R + R+S  +RD+              P
Sbjct: 551 PSEEREHRQSRSPSKERDR-RRWRSPSKERERRQS-RSSSEERDHSRSRSPNKQSGYSRP 608

Query: 439 RASSPSRATRDNPTTSCAQRDNPRASRTSS----PNRATRDNPRTSCAQRDNPRASSPSR 494
           RASS  +A   + T S  +  N   SRTSS    P+++T   PR+   +R   R SS S+
Sbjct: 609 RASSKEKAHSRSRTPS--KEGNHSQSRTSSKESDPSQST--VPRSPDWKRSPTRTSSLSQ 664

Query: 495 ATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASS 540
               + T+S +    P   +T S + +  D   TS A     R+SS
Sbjct: 665 NRTPSKTSSHSPSTFPSGGQTLSQDDSQAD-ATTSKATLPGERSSS 709



 Score = 37.4 bits (85), Expect = 0.18
 Identities = 72/306 (23%), Positives = 104/306 (33%), Gaps = 38/306 (12%)

Query: 1243 SPSPGSSGGSRGSAPPGETRHNLEREEYTVLADLPPPR-------RLAQRQPGPQAQCSS 1295
            S SP    G   S  P + R +          D    R       R   R P     CS 
Sbjct: 380  SSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCS- 438

Query: 1296 GGRTHSPGRAEVE---RLFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPS 1352
              R+ SP +A      R   + R  S +    +A+D  RS+ PS+ +        S    
Sbjct: 439  --RSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERD 496

Query: 1353 RQVTMLPAK--QAELTRRSQAEPPHPWSPEKRPEGDRQLQGSPLP----PRTSARTP--E 1404
             + +  P+K  Q   +R S  E  H  S  + P  +RQ + S  P     R+ +R+P  E
Sbjct: 497  HRRSRSPSKERQCRQSRSSSKERDHRRS--RSPSKERQRRQSRSPNKERDRSQSRSPSEE 554

Query: 1405 RELRTQR--PLESGQAGPRQPLGVWQSQEEPPGSQGPHRHLERSWSSQEGGLGPGGWWGC 1462
            RE R  R    E  +   R P    + ++    S+       RS + Q G   P      
Sbjct: 555  REHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKE 614

Query: 1463 GEPSLGAAKAPEGAWGGTSREYKESWGQPEA------WEEKPT-------HELPRELGKR 1509
               S     + EG    +    KES            W+  PT       +  P +    
Sbjct: 615  KAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSH 674

Query: 1510 SPLTSP 1515
            SP T P
Sbjct: 675  SPSTFP 680


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score =  132 bits (332), Expect = 4e-30
 Identities = 186/698 (26%), Positives = 283/698 (40%), Gaps = 107/698 (15%)

Query: 132 SDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGPRADSS---- 187
           + PT +P +A+   T + +S+            PS   L    PR   +G  + +S    
Sbjct: 11  ASPTRTPSTASLTGTPSRASLTGTPSTASLMGTPSRASLTGTPPRASLKGTTSMASLMVS 70

Query: 188 --------QRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRST 239
                    ++ SLLTR+P     A  K+              + +R  S  SL R  S 
Sbjct: 71  PSRASLTRMQSSSLLTRTP---SMASLKRMPPRASRTRTLPRASLMRRPSTASLTRSPSR 127

Query: 240 LTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRAS-----------------SPH 282
            +  +  TP     S T   + A    ++A+ TR  PRAS                 SP 
Sbjct: 128 ASLTT--TPSRASLSMTPSTAAALTMPSRASLTRTPPRASLTMTPSTASLTRTPPRASPT 185

Query: 283 RITQRDTSRASSTQQEISRASSTQQET---SRASSTQEDTPRASSTQEDTPRASSTQW-- 337
            +  R +     +   +++  ST   T   SRAS T   TP  +S     PRAS +    
Sbjct: 186 GMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPT--GTPPRASPTGSPPRASLSMMPS 243

Query: 338 -----NTPRASSP----SRS--TQLDNPRTSSTQQDNPQTSFPTCTPQREN----PRTPC 382
                 TP  +SP    SR+  T++D+  + +     P T+ PT TP R +    P T  
Sbjct: 244 TALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTGTPSRASLSMTPSTAS 303

Query: 383 VQQDDPRASSP---NRTTQRENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPR 439
           + +  PRAS     +RT+  +   T+   R  P+AS T +P+RA+     ++ +    P 
Sbjct: 304 LMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRASITRTPSRASPTGKPSTASPTGTPS 363

Query: 440 ASSPSRATRDNPTTSCAQRDNPRASRTSSPNRAT-RDNPRTSCAQRDNPRASSPSRATRD 498
            +SP+     +P+T+     +  AS T +P RA+    P T+   R  PRAS     +R 
Sbjct: 364 RASPT----GSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPPRASPTGMLSRT 419

Query: 499 NPT----TSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCA 554
           + T    T+   R  PRAS T +P RA+     T    R +P  +    +   +P+T+  
Sbjct: 420 SITKMDSTASPTRTPPRASPTGTPPRASP----TGTPSRASPTGTQSTASPTGSPSTASP 475

Query: 555 QRDNPRASRTSSPNRA--TRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASR 612
                 AS T SP+RA  TR   R S  + +               +T+   R   RAS 
Sbjct: 476 TGSPSTASPTGSPSRASLTRTPSRASLTKME---------------STASITRTPSRASP 520

Query: 613 TSSPNRAT-RDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRAS--SPNRTIQQ 669
           T +P+ A+   +P T+ A        SP+R     +P  +   R   RAS  +P+R    
Sbjct: 521 TWTPSTASPTGSPSTALAM------GSPSRAALTRTPSRASLTRTPSRASLTTPSRASLT 574

Query: 670 ENPRTSCALRDNPRAS---SPSRTIQQENPRTSCAQRDDPRAS---SPNRTTQQENPRTS 723
             P T    R  P AS    PSRT     P ++   + D  AS   +P R +  E P  +
Sbjct: 575 RTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSALLTKMDSTASITRTPPRASPTETPPRA 634

Query: 724 CARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNR 761
                 PRAS    T  R +P T    R +P   +P+R
Sbjct: 635 SPTGTPPRASPTG-TPPRASP-TGTPPRASP-TGTPSR 669



 Score =  132 bits (331), Expect = 5e-30
 Identities = 200/757 (26%), Positives = 312/757 (41%), Gaps = 133/757 (17%)

Query: 244 SSMTPHSGPRSTTSQASPAQRDTAQAASTREI----PRAS---SPHRITQRDTSRASSTQ 296
           S  +P   P + +   +P++       ST  +     RAS   +P R + + T+  +S  
Sbjct: 9   SRASPTRTPSTASLTGTPSRASLTGTPSTASLMGTPSRASLTGTPPRASLKGTTSMASLM 68

Query: 297 QEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRT 356
              SRAS T+ ++S   S    TP  +S +   PRAS T+   PRAS   R      P T
Sbjct: 69  VSPSRASLTRMQSS---SLLTRTPSMASLKRMPPRASRTR-TLPRASLMRR------PST 118

Query: 357 SSTQQDNPQTSFPTCTPQREN----PRTPCVQQDDPRAS---SPNRTTQRENSRTSCAQR 409
           +S  + +P  +  T TP R +    P T        RAS   +P R +      T+   R
Sbjct: 119 ASLTR-SPSRASLTTTPSRASLSMTPSTAAALTMPSRASLTRTPPRASLTMTPSTASLTR 177

Query: 410 DNPKASRTSSPNRATRDN-PRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSS 468
             P+AS T  P+R +    P T+   + +  AS     +R +PT +      PRAS T S
Sbjct: 178 TPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGT-----PPRASPTGS 232

Query: 469 PNRATRDN-PRTSCAQRDNPRASSPSRATRDNPT----TSCAQRDNPR---ASRTSSPNR 520
           P RA+    P T+   R  PRAS     +R + T    T+   R   R   AS T +P+R
Sbjct: 233 PPRASLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTGTPSR 292

Query: 521 ATRD-NPRTSCAQRDNPRASSPNRAARDNPT----TSCAQRDNPRASRTSSPNRATRDNP 575
           A+    P T+   R  PRAS     +R + T    T+   R  PRAS T +P+RA+    
Sbjct: 293 ASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRASITRTPSRASPTGK 352

Query: 576 RTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRAT-RDNPRTSCAQRDNP 634
            ++ +    P  +SP      +P+T+     +  AS T +P RA+    P T+   R  P
Sbjct: 353 PSTASPTGTPSRASPT----GSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPP 408

Query: 635 RASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQE 694
           RAS     +     RTS  + D    +SP RT  + +P  +      P  +SP+ T  + 
Sbjct: 409 RASPTGMLS-----RTSITKMDS--TASPTRTPPRASPTGT------PPRASPTGTPSRA 455

Query: 695 NP---RTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQR 751
           +P   +++ +    P  +SP  +    +P  S +R    R  SR    + ++  T+   R
Sbjct: 456 SPTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSRASLTKMES--TASITR 513

Query: 752 DNPRASSPNRTIQQENLRTSCTRQDNPRTS----SPNRA--TRDNPRTSCAQRDNLRAS- 804
             P  +SP  T       ++ +   +P T+    SP+RA  TR   R S  +  + RAS 
Sbjct: 514 -TPSRASPTWT------PSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPS-RASL 565

Query: 805 -SPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDN 863
            +P RA+    P T +   +P S+S      +TS T   +     T+ D T S +     
Sbjct: 566 TTPSRASLTRTPSTVLLTRMPPSASPTGMPSRTSPTGMPS-SALLTKMDSTASIT----- 619

Query: 864 PGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSS 923
                             +P R++    P  +SP  T         P R + +  P  +S
Sbjct: 620 -----------------RTPPRASPTETPPRASPTGT---------PPRASPTGTPPRAS 653

Query: 924 PSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDP 960
           P+                  G  P+ S    P++  P
Sbjct: 654 PT------------------GTPPRASPTGTPSRASP 672



 Score =  119 bits (297), Expect = 5e-26
 Identities = 204/754 (27%), Positives = 294/754 (38%), Gaps = 159/754 (21%)

Query: 369  PTCTPQRENP-RTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSSPNRATRDN 427
            PT TP R +P RTP          +P+R +      T+       +AS T +P RA+   
Sbjct: 4    PTRTPSRASPTRTPSTAS---LTGTPSRASLTGTPSTASLMGTPSRASLTGTPPRASLKG 60

Query: 428  PRTSCAQRDNP------RASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSC 481
              +  +   +P      R  S S  TR  P+ +  +R  PRASRT               
Sbjct: 61   TTSMASLMVSPSRASLTRMQSSSLLTR-TPSMASLKRMPPRASRT--------------- 104

Query: 482  AQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRD-NPRTSCAQRDNPRAS- 539
              R  PRAS   R     P+T+   R   RAS T++P+RA+    P T+ A     RAS 
Sbjct: 105  --RTLPRASLMRR-----PSTASLTRSPSRASLTTTPSRASLSMTPSTAAALTMPSRASL 157

Query: 540  --SPNRAARD-NPTTSCAQRDNPRASRTSSPNRATRDN-PRTSCAQRDNPRASSPNRATR 595
              +P RA+    P+T+   R  PRAS T  P+R +    P T+   + +  AS     +R
Sbjct: 158  TRTPPRASLTMTPSTASLTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSR 217

Query: 596  DNPTTSCAQRDNPRASRTSSPNRATRDN-PRTSCAQRDNPRASSPNRTTQQDSPRTSCAR 654
             +PT +      PRAS T SP RA+    P T+   R  PRAS     +     RTS  +
Sbjct: 218  ASPTGT-----PPRASPTGSPPRASLSMMPSTALLIRTPPRASPTGMLS-----RTSLTK 267

Query: 655  RDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSP--- 711
             D    S+ + T     P T+          +PSR      P T+   R  PRAS     
Sbjct: 268  MD----STASITRTPSRPSTASP------TGTPSRASLSMTPSTASLMRMLPRASPTGML 317

Query: 712  NRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTS 771
            +RT+  +   T+   R  PRAS   RT  R +P         P  +SP  T  + +    
Sbjct: 318  SRTSLTKMDSTASISRTPPRASI-TRTPSRASPT------GKPSTASPTGTPSRAS---- 366

Query: 772  CTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTC-IQQNIPRSSSTQ 830
                    T SP+ A+     ++ +        +P RA+    P T  + +  PR+S T 
Sbjct: 367  -------PTGSPSTASLTGLSSTASP-----TGTPPRASPTGTPSTASLTRKPPRASPTG 414

Query: 831  QDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWN 890
              + +TS TK D+            + S  R  P  S +            +P R++   
Sbjct: 415  MLS-RTSITKMDS------------TASPTRTPPRASPT-----------GTPPRASPTG 450

Query: 891  NPRNSSPHRTNKDIPWASFPLRPTQSDGPRTS----SPSRSKQSEVP----------WAS 936
             P  +SP  T         P   + +  P T+    SPSR+  +  P           AS
Sbjct: 451  TPSRASPTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSRASLTKMESTAS 510

Query: 937  IALRPTQGDRPQTSSPSRPAQHDPPQSSFG-PTQYNL---PSRAT-------SSSHNPGH 985
            I   P++     T S + P        + G P++  L   PSRA+       +S   P  
Sbjct: 511  ITRTPSRASPTWTPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSR 570

Query: 986  QSTSRTSSPVY-----PAAYGAPLTS-PEPSQPPCAVCIGHRDA--------PRAS---S 1028
             S +RT S V      P+A    + S   P+  P +  +   D+        PRAS   +
Sbjct: 571  ASLTRTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSALLTKMDSTASITRTPPRASPTET 630

Query: 1029 PPRYLQHDPFPFFPEPRA-PESEPPHHEPPYIPP 1061
            PPR       P    PRA P   PP   P   PP
Sbjct: 631  PPR-----ASPTGTPPRASPTGTPPRASPTGTPP 659



 Score =  107 bits (267), Expect = 1e-22
 Identities = 123/437 (28%), Positives = 195/437 (44%), Gaps = 51/437 (11%)

Query: 237 RSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQ 296
           R++LT+  S    +   S  S ASP    T   AS    P  +S  R+  R     +S  
Sbjct: 262 RTSLTKMDSTASITRTPSRPSTASPT--GTPSRASLSMTPSTASLMRMLPR-----ASPT 314

Query: 297 QEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRAS---SPSRSTQLDN 353
             +SR S T+ +++  +S     PRAS T+  TP  +S       AS   +PSR++   +
Sbjct: 315 GMLSRTSLTKMDST--ASISRTPPRASITR--TPSRASPTGKPSTASPTGTPSRASPTGS 370

Query: 354 PRTSSTQQDNPQTSFPTCTPQRENPR----TPCVQQDDPRASSP---NRTTQRENSRTSC 406
           P T+S    +  T+ PT TP R +P     T  + +  PRAS     +RT+  +   T+ 
Sbjct: 371 PSTASLTGLS-STASPTGTPPRASPTGTPSTASLTRKPPRASPTGMLSRTSITKMDSTAS 429

Query: 407 AQRDNPKASRTSSPNRAT------RDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDN 460
             R  P+AS T +P RA+      R +P T      +P  S  + +   +P+T+      
Sbjct: 430 PTRTPPRASPTGTPPRASPTGTPSRASP-TGTQSTASPTGSPSTASPTGSPSTASPTGSP 488

Query: 461 PRASRTSSPNRATRDNPRTSCAQRDNPRASSPS-----RATRDNPTTSCAQRDNPRASRT 515
            RAS T +P+RA+     ++ +    P  +SP+      +   +P+T+ A     RA+ T
Sbjct: 489 SRASLTRTPSRASLTKMESTASITRTPSRASPTWTPSTASPTGSPSTALAMGSPSRAALT 548

Query: 516 SSPNRA--TRDNPRTSCAQRDNPRASSPNRAARDN-PTTSCAQRDNPRASRTSSPNRATR 572
            +P+RA  TR   R S         ++P+RA+    P+T    R  P AS T  P+R + 
Sbjct: 549 RTPSRASLTRTPSRASL--------TTPSRASLTRTPSTVLLTRMPPSASPTGMPSRTSP 600

Query: 573 DN-PRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQR 631
              P ++   + +  AS      R +PT +      PRAS T +P RA+        +  
Sbjct: 601 TGMPSSALLTKMDSTASITRTPPRASPTET-----PPRASPTGTPPRASPTGTPPRASPT 655

Query: 632 DNPRASSPNRTTQQDSP 648
             P  +SP  T  + SP
Sbjct: 656 GTPPRASPTGTPSRASP 672



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 142/559 (25%), Positives = 216/559 (38%), Gaps = 84/559 (15%)

Query: 53  LPRCPPAPEDPLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEE-GPTAAPRSRSRELEA 111
           L R PP     ++ ST+          R  P+  P+   G+P    PT  P + S     
Sbjct: 157 LTRTPPRASLTMTPSTASLT-------RTPPRASPT---GMPSRTSPTGMPSTASLTKMD 206

Query: 112 VPYLEGLTTSLCGSCNEDPGSDPTSSPDSA-------------TPDDTSNSSSVDWDTVE 158
                  T S        P + PT SP  A             TP   S +  +   ++ 
Sbjct: 207 STASITRTLSRASPTGTPPRASPTGSPPRASLSMMPSTALLIRTPPRASPTGMLSRTSLT 266

Query: 159 RQEEEAPSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSA 218
           + +  A          P RP       +  RA   +T S         +   TG   R++
Sbjct: 267 KMDSTAS-----ITRTPSRPSTASPTGTPSRASLSMTPSTASLMRMLPRASPTGMLSRTS 321

Query: 219 GQHWARLRGESGLSLERHRSTLTQASSMTPHSGPRSTTSQA-SPAQRDTAQAASTREIPR 277
                ++   + +S    R+++T+  S    +G  ST S   +P++     + ST  +  
Sbjct: 322 ---LTKMDSTASISRTPPRASITRTPSRASPTGKPSTASPTGTPSRASPTGSPSTASLTG 378

Query: 278 ASS-------PHRITQRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTP 330
            SS       P R +   T   +S  ++  RAS T    SR S T+ D+   +S     P
Sbjct: 379 LSSTASPTGTPPRASPTGTPSTASLTRKPPRASPTGM-LSRTSITKMDS--TASPTRTPP 435

Query: 331 RASSTQWNTPRAS---SPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDD 387
           RAS T    PRAS   +PSR++      T+S    +P T+ PT +P   +P     +   
Sbjct: 436 RASPTG-TPPRASPTGTPSRASPTGTQSTASPT-GSPSTASPTGSPSTASPTGSPSRASL 493

Query: 388 PRASSPNRTTQRENSRTSCAQRDNPKASRTSSPNRAT-RDNPRTSCAQRDNPRASSPSRA 446
            R  +P+R +  +   T+   R   +AS T +P+ A+   +P T+ A        SPSRA
Sbjct: 494 TR--TPSRASLTKMESTASITRTPSRASPTWTPSTASPTGSPSTALAM------GSPSRA 545

Query: 447 TRDN-PTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPT---- 501
                P+ +   R   RAS T+    +    P T    R  P AS     +R +PT    
Sbjct: 546 ALTRTPSRASLTRTPSRASLTTPSRASLTRTPSTVLLTRMPPSASPTGMPSRTSPTGMPS 605

Query: 502 ---------TSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTS 552
                    T+   R  PRAS T +P RA+             PRAS      R +PT +
Sbjct: 606 SALLTKMDSTASITRTPPRASPTETPPRASPTG--------TPPRASPTGTPPRASPTGT 657

Query: 553 CAQRDNPRASRTSSPNRAT 571
                 PRAS T +P+RA+
Sbjct: 658 -----PPRASPTGTPSRAS 671



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 162/698 (23%), Positives = 243/698 (34%), Gaps = 109/698 (15%)

Query: 634  PRASSPNRTTQQDSPRTSCARRDDPRAS---SPNRTIQQENPRTSCALRDNPRASSPSRT 690
            P   +P+R +   +P T+       RAS   +P+       P  +      PRAS    T
Sbjct: 3    PPTRTPSRASPTRTPSTASLTGTPSRASLTGTPSTASLMGTPSRASLTGTPPRASLKGTT 62

Query: 691  IQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQ 750
                +   S ++    R  S +  T+   P  +  +R  PRAS R RT+    PR S  +
Sbjct: 63   -SMASLMVSPSRASLTRMQSSSLLTR--TPSMASLKRMPPRAS-RTRTL----PRASLMR 114

Query: 751  RDNPRASSPNRTIQQENLRTSCTRQDNPRTSS-------PNRA--TRDNPRTSCAQRDNL 801
            R  P  +S  R+  + +L T+ +R     T S       P+RA  TR  PR S     + 
Sbjct: 115  R--PSTASLTRSPSRASLTTTPSRASLSMTPSTAAALTMPSRASLTRTPPRASLTMTPST 172

Query: 802  RA--SSPIRATQQDNPRTCIQQNIPRSSS-TQQDNPKTSCTKRDNLRPTCTQRDRTQSFS 858
             +   +P RA+    P       +P ++S T+ D+  +         PT T    + + S
Sbjct: 173  ASLTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPPRASPTGS 232

Query: 859  FQRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDG 918
              R +     S        L   +P R++       +S  + +        P RP  S  
Sbjct: 233  PPRASLSMMPSTA------LLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRP--STA 284

Query: 919  PRTSSPSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATS 978
              T +PSR        AS+++ P+      T+S  R      P      T         S
Sbjct: 285  SPTGTPSR--------ASLSMTPS------TASLMRMLPRASPTGMLSRTSLTKMDSTAS 330

Query: 979  SSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPF 1038
             S  P   S +RT S   P   G P T+     P  A   G   +P  +S          
Sbjct: 331  ISRTPPRASITRTPSRASPT--GKPSTASPTGTPSRASPTG---SPSTAS---------L 376

Query: 1039 PFFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAE-HQ 1097
                   +P   PP   P   P    +  R  PRAS         P   L  TS  +   
Sbjct: 377  TGLSSTASPTGTPPRASPTGTPSTASLT-RKPPRAS---------PTGMLSRTSITKMDS 426

Query: 1098 CQSPQHEPLQLPAPVCIGYRDAPRAS---SPPRQAPEPSLLFQDLPRASTESLVPSMDSL 1154
              SP   P              PRAS   +PPR +P  +      P  ++ +   S  S 
Sbjct: 427  TASPTRTP--------------PRASPTGTPPRASPTGT------PSRASPTGTQSTASP 466

Query: 1155 HECPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLAPSTDSLHGSPVLIP 1214
               P   +P       +PS +SP       SL  + P   S+  +  ST S+  +P    
Sbjct: 467  TGSPSTASPT-----GSPSTASPTGSPSRASLT-RTPSRASLTKME-STASITRTPSRAS 519

Query: 1215 QVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVLA 1274
                     P  +SP   P + LA  +PS +  +   SR S     +R +L       L 
Sbjct: 520  PTW-----TPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRASLT 574

Query: 1275 DLPPPRRLAQRQP--GPQAQCSSGGRTHSPGRAEVERL 1310
              P    L +  P   P    S    T  P  A + ++
Sbjct: 575  RTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSALLTKM 612



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 149/658 (22%), Positives = 221/658 (33%), Gaps = 107/658 (16%)

Query: 778  PRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTS 837
            P T +P+RA+     ++ +        +P RA+    P T      P  +S     P+ S
Sbjct: 3    PPTRTPSRASPTRTPSTASL-----TGTPSRASLTGTPSTASLMGTPSRASLTGTPPRAS 57

Query: 838  CTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSP 897
                 ++        R              +S    Q  +L   +P  ++    P  +S 
Sbjct: 58   LKGTTSMASLMVSPSR--------------ASLTRMQSSSLLTRTPSMASLKRMPPRASR 103

Query: 898  HRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPW-ASIALRPTQGDRPQTSSPSRPA 956
             RT   +P AS   RP  S    T SPSR+  +  P  AS+++ P+       + PSR +
Sbjct: 104  TRT---LPRASLMRRP--STASLTRSPSRASLTTTPSRASLSMTPSTA--AALTMPSRAS 156

Query: 957  -QHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCA 1015
                PP++S   T    PS A+ +   P     S T  P   +  G P T+        A
Sbjct: 157  LTRTPPRASLTMT----PSTASLTRTPP---RASPTGMPSRTSPTGMPSTASLTKMDSTA 209

Query: 1016 VCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRASS 1075
                 R   RAS           P    PRA  +  P      + P+  +  R  PRAS 
Sbjct: 210  SIT--RTLSRAS-----------PTGTPPRASPTGSPPRASLSMMPSTALLIRTPPRAS- 255

Query: 1076 PPRHTQFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRASSPPRQA----PE 1131
                    P   L  TS  +    +        P+        A    +P R +    P 
Sbjct: 256  --------PTGMLSRTSLTKMDSTASITRTPSRPST-------ASPTGTPSRASLSMTPS 300

Query: 1132 PSLLFQDLPRASTESLVP-----SMDSLHECPHIPTPVCIGHRDAPSFSSPPRQAPEPSL 1186
             + L + LPRAS   ++       MDS       P    I     PS +SP  +      
Sbjct: 301  TASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRASITR--TPSRASPTGK------ 352

Query: 1187 FFQDPPGTSMESLAPSTDSLHGSPVLIPQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSP 1246
                 P T+  +  PS  S  GSP       +    +P   +PPR  P+      PS + 
Sbjct: 353  -----PSTASPTGTPSRASPTGSPSTASLTGLSSTASP-TGTPPRASPTG----TPSTAS 402

Query: 1247 GSSGGSRGSAPPGETRHNLEREEYTVLADLPPPRRLAQRQPGPQAQCSSGGRTHSPGRAE 1306
             +    R S     +R ++ + + T      PPR      P   +   +  R    G   
Sbjct: 403  LTRKPPRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQS 462

Query: 1307 VERLFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPSRQVTMLPAKQAELT 1366
                 G     S       A   G     S  ++ L R      PSR         A +T
Sbjct: 463  TASPTGSPSTASPTGSPSTASPTG-----SPSRASLTR-----TPSRASLTKMESTASIT 512

Query: 1367 RR-SQAEPPHPWSPE-KRPEGDRQLQGSPLPPRTSA--RTPERELRTQRPLESGQAGP 1420
            R  S+A P   W+P    P G      +   P  +A  RTP R   T+ P  +    P
Sbjct: 513  RTPSRASP--TWTPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTP 568



 Score = 32.3 bits (72), Expect = 5.7
 Identities = 53/226 (23%), Positives = 73/226 (32%), Gaps = 30/226 (13%)

Query: 1499 THELPRELGKRSPLTSPPEN--WGGPAESSQSWHSGTPTAVGWGAEGACPYPRGSERRPE 1556
            T  + R L + SP  +PP     G P  +S S    T   +      +   P G   R  
Sbjct: 208  TASITRTLSRASPTGTPPRASPTGSPPRASLSMMPSTALLIRTPPRAS---PTGMLSRTS 264

Query: 1557 LDWRD-LLGLLRAPGEGVWARVPSLDWEGLLEL------LQARLPRKDPAGHRDDLARAL 1609
            L   D    + R P     A          L +      L   LPR  P G    L+R  
Sbjct: 265  LTKMDSTASITRTPSRPSTASPTGTPSRASLSMTPSTASLMRMLPRASPTGM---LSRTS 321

Query: 1610 GPELGPPGTNDVPEQESHSQPEGWAEATPVNGHSPALQSQSPVQLPSPACTSTQWPKIKV 1669
              ++      D     S + P      TP           SP   PS A  +    +   
Sbjct: 322  LTKM------DSTASISRTPPRASITRTPSRA--------SPTGKPSTASPTGTPSRASP 367

Query: 1670 TRGPATATLAGLEQT-GPLGSRSTAKGPSLPELQFQPEEPEESEPS 1714
            T  P+TA+L GL  T  P G+   A     P       +P  + P+
Sbjct: 368  TGSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPPRASPT 413


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score =  104 bits (260), Expect = 9e-22
 Identities = 257/1276 (20%), Positives = 442/1276 (34%), Gaps = 169/1276 (13%)

Query: 42   SPSGAEVPYCDLPRCPPAPEDPLSASTSG---------CQSVVDPGLRPGPKRGPSPSAG 92
            S + A  P    P+  P  +   SA+ S            S +   + P  KR P+    
Sbjct: 755  SHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGS 814

Query: 93   LPEEGPTAAPRSRSRELEAVPYLEGLTTSLCGSCNEDPGSDPTSSPDSATPDDTSNSSSV 152
               + P     S    +EA  +L   + S  GS  + P +  T SP   +P      S+V
Sbjct: 815  AGPDTPIGNLSSPVSPVEA-SFLPENSLSFQGS-KDSPAT--THSPTPPSPKGAPTPSAV 870

Query: 153  D-----WDTVERQEEEAPSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAGQK 207
                    T+  +E   PS     V +P  P+EGP   + ++AP+L   S     ++ +K
Sbjct: 871  TPLSPKGVTLPPKETPTPS----VVNLPF-PKEGPATPAPKQAPALSMTS-----SSPKK 920

Query: 208  KEDTGGGGRSAGQHWARLRGESGLSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTA 267
               T              +G       +   T   A+  +P  GP + + + +P     A
Sbjct: 921  ARATPAP-----------KGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP-PAA 968

Query: 268  QAASTREIPRASSPHRITQRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQE 327
               S +  P   SP        +   S +   +  S     T  A +    +P+ S    
Sbjct: 969  TPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP--SPKGSPAAT 1026

Query: 328  DTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQ--Q 385
              P+ +ST    P A+ PS      +P  +   +  P T   T    +  P TP ++   
Sbjct: 1027 PFPKGASTP---PAATPPSPK---GSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP 1080

Query: 386  DDPRASSPN------RTTQRENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPR 439
              P A+ P+        + +       A   +PK    + P++     P T  A   +P+
Sbjct: 1081 TPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGA---PTTPAATPPSPK 1137

Query: 440  ASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDN 499
                +   +  PTT  A   +P+    + P +     P T  A   +P+    + + +  
Sbjct: 1138 GGLATPPPKGAPTTPAATPPSPKGGLATPPPKGA---PTTPAATPPSPKGGLATPSPKGA 1194

Query: 500  PTTSCAQRDNPRAS-RTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDN 558
            PTT  A   +P+    T SP  A    P T  A   +P+      + +  PTT  A   +
Sbjct: 1195 PTTPAATPPSPKGGLATPSPKGA----PTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1250

Query: 559  PRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNR 618
            P+    + P +     P  +        A+ P++     P  +     +P+    +SP +
Sbjct: 1251 PKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGA---PNPAVVTPPSPKGGPATSPPK 1307

Query: 619  ATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASS--PNRTIQQENPRTSC 676
                 P    A   +P+ S P     + +P         P+ +   P  T   +   T+ 
Sbjct: 1308 GA---PTPPAATPPSPKGS-PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTP 1363

Query: 677  ALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRN 736
            + ++ P   + + + +     T  + +  P   SP     + +P +      +P+ +   
Sbjct: 1364 SSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSP-----KGDPTSPAVIPLSPKKAPAT 1418

Query: 737  RTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPN------RATRDN 790
              + R+   T       P A +P   +  +    +   +  P T S          T  +
Sbjct: 1419 -PVTREGAATPSKGDLTPPAVTP---VSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPS 1474

Query: 791  PRTSCAQRDNLRASSPIRATQQDNPRTC--IQQNIPRSSSTQQDNPKTSCTKRDNLRPTC 848
            P+   A +    +SSP +A     P     +   IP   S+ ++ P T  ++RD + PT 
Sbjct: 1475 PKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIP---SSPKEVPATPSSRRDPIAPTA 1531

Query: 849  TQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWAS 908
            T           +  P T + +       +   SP ++     P+ +    ++K+   AS
Sbjct: 1532 TL--------LSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKE---AS 1580

Query: 909  FPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPT 968
             P   T S      SP   K+  +P A  +  P +       +P+ PA   PP    GP 
Sbjct: 1581 SPPAVTPSTYKGAPSP---KELLIPPAVTSPSPKE-------APTPPAV-TPPSPEKGPA 1629

Query: 969  QYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASS 1028
                    TS    P     S TS        GA +       P        ++   A +
Sbjct: 1630 TPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPA 1689

Query: 1029 PPRYLQHDPFPFFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFL 1088
            P    +  P    P  + P+++      P I P        A   S  P  T   P P L
Sbjct: 1690 P----ESTPIITAPTRKGPQTKKSSATSPPICP-----DPSAKNGSKGPLST-VAPAPLL 1739

Query: 1089 PDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQDLPRASTESLV 1148
            P   D+    +                 +DA  +   P   PE S     L  A+ E ++
Sbjct: 1740 PVQKDSSKTAKG----------------KDASHSPKGPLAPPE-SKASTPLTAAAFEKVL 1782

Query: 1149 PSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMES----LAPSTD 1204
            P  +S         PV +    +P  + PP+Q      F    PG  +ES    LAP+ D
Sbjct: 1783 PKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQ-----FLPSSPGLVLESPSKPLAPA-D 1836

Query: 1205 SLHGSPVLIPQVCIG---------HRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGS 1255
                 P++ P+   G         +   P+++  P   PS     A  P   ++ GS   
Sbjct: 1837 EDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPS-----AKQPVTKNNKGSGTE 1891

Query: 1256 APPGETRHNLEREEYT 1271
            +   E+   LE ++ T
Sbjct: 1892 SDSDESVPELEEQDST 1907



 Score = 81.6 bits (200), Expect = 8e-15
 Identities = 219/1060 (20%), Positives = 341/1060 (32%), Gaps = 151/1060 (14%)

Query: 243  ASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEISRA 302
            ASSMT    P    S AS  + D+         P ++ P   +   T   ++   E +  
Sbjct: 605  ASSMT---SPLGVNSSASVIKTDSYAG------PDSAGPLLKSSLITPTVAAFPLESADP 655

Query: 303  SSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQD 362
            +     T++ +ST   T         +P    T    P+       T    P   +  ++
Sbjct: 656  AGVAPTTAKGTSTYTTTA--------SPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASEN 707

Query: 363  NPQTSFP--TCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSSP 420
             P    P  TC P       P + +  P  S P   T     +       +  A   SSP
Sbjct: 708  CPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSP 767

Query: 421  NRATRDNPRTSC-----------AQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSP 469
                 ++   S            A   +P   S S  T+  PT   +   +      SSP
Sbjct: 768  KECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSP 827

Query: 470  NRATRDN--PRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPR 527
                  +  P  S + +     S  S AT  +PT        P      +P+  T  +P+
Sbjct: 828  VSPVEASFLPENSLSFQ----GSKDSPATTHSPTP-------PSPKGAPTPSAVTPLSPK 876

Query: 528  -TSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPR 586
              +   ++ P  S  N         + A +  P  S TSS  +  R  P    A +  P 
Sbjct: 877  GVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATP----APKGIPA 932

Query: 587  ASSPNRATRDNPTTSCAQRDNPRAS-RTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQ 645
            + SP  A    PT   A   +P+    T SP  A      T  + +  P   SP     +
Sbjct: 933  SPSPKGA----PTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSP-----K 983

Query: 646  DSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDD 705
             +P    A    P+            P T      +P+ +     +   +P+ S A    
Sbjct: 984  GAPTPPAATPPSPKGG----------PATP-----SPKGAPTPPAVTPPSPKGSPAATPF 1028

Query: 706  PRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQ 765
            P+ +S        +P+ S A    P+ +         +P+   A      A +P      
Sbjct: 1029 PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAA--- 1085

Query: 766  ENLRTSCTRQDNPRTSSPN------RATRDNPRTSCAQRDNLRASSPIRATQQDNPR--- 816
                T  + +  P T SP        AT  +P+   A   +  A +   AT   +P+   
Sbjct: 1086 ----TPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPP-SPKGGL 1140

Query: 817  -TCIQQNIPRSSSTQQDNPK----TSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQC 871
             T   +  P + +    +PK    T   K     P  T              P +     
Sbjct: 1141 ATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT--------------PPSPKGGL 1186

Query: 872  CTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSE 931
             T      P++P  +    +P+      + K  P       P+   G  T SP  +    
Sbjct: 1187 ATPSPKGAPTTPAATPP--SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA---- 1240

Query: 932  VPWASIALRPTQGDRPQTSSPS---RPAQHDPPQSSFG---PTQYNLPSRATSSSHNP-- 983
             P    A  P+    P T  P     P    PP    G   P     P+ A  +  +P  
Sbjct: 1241 -PTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG 1299

Query: 984  GHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFF-P 1042
            G  ++    +P  PAA     T P P   P          P A +PP        P   P
Sbjct: 1300 GPATSPPKGAPTPPAA-----TPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP 1354

Query: 1043 EPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQSPQ 1102
              +   + P   E P  PPA    H+  P A +PP   +    P             SP+
Sbjct: 1355 SSKGGPTTPSSKEGP-TPPAATPSHKGGP-AMTPPSPKRGPAIP-------------SPK 1399

Query: 1103 HEPLQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQDLPRASTESLVPSMDSLHECPHIPT 1162
             +P   PA + +  + AP        A  PS      P  +  SL  +  +        T
Sbjct: 1400 GDPTS-PAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPAT 1458

Query: 1163 PVCIGHRDAPSFSSP-PRQAPEPSLFFQDPPGTSMESLAPSTDSLHGSPVLIPQVCIGHR 1221
            P   G    P+ + P P++ P P    +    +S    AP+T +  G+P L   +    +
Sbjct: 1459 PSSKGDPTLPAVTPPSPKEPPAP----KQVATSSSPKKAPATPAPMGAPTLPAVIPSSPK 1514

Query: 1222 DAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGET 1261
            + P   S  R P +  A L    +P +        PP  T
Sbjct: 1515 EVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMT 1554



 Score = 72.0 bits (175), Expect = 6e-12
 Identities = 232/965 (24%), Positives = 328/965 (33%), Gaps = 163/965 (16%)

Query: 918  GPRTSSPSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRAT 977
            GP ++ P        P  ++A  P +   P   +P+         ++  P      S A 
Sbjct: 628  GPDSAGPLLKSSLITP--TVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAP 685

Query: 978  SSSHNPGHQSTSRTSSPVYPAAYGAPLT-SPEPSQPPCAVCIGHRDAPRASSPPRYLQHD 1036
             +  +P  + T  T   V  A+   P+  SP+ +  P A  +   + P++   P      
Sbjct: 686  KN--HPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSP------ 737

Query: 1037 PFPFFPEPRAPESEPPHHEPPYIPPAVCIGHRDA--PRASSPPRHTQFDP---------- 1084
                        S PP   PP       I H  A  P ASSP      D           
Sbjct: 738  ------------SLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKG 785

Query: 1085 -FPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAP--RASSP--PRQA---PEPSLLF 1136
               +L D+        SPQ +  + P        D P    SSP  P +A   PE SL F
Sbjct: 786  TLTYLADSPSPLGVSVSPQTK--RPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSF 843

Query: 1137 Q---DLPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQAPEPSL----FFQ 1189
            Q   D P  +     PS          PTP  +        + PP++ P PS+    F +
Sbjct: 844  QGSKDSPATTHSPTPPSPKGA------PTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPK 897

Query: 1190 DPPGTSMESLAPSTDSLHGSPVLIPQVCIGHRDAPR---ASSPPRHPPSDLAFLAPSPSP 1246
            + P T     AP+      SP            AP+   AS  P+  P+  A   PSP  
Sbjct: 898  EGPATPAPKQAPALSMTSSSPKKARAT-----PAPKGIPASPSPKGAPTPPAATPPSPKG 952

Query: 1247 GSSGGSRGSAP--PGETRHNLEREEYTVL---ADLPPPRRLAQRQPGPQAQCSSGGRTHS 1301
            G +  S   AP  P  T  + +    T     A  PP    A   P P+     G  T S
Sbjct: 953  GPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPP----AATPPSPKG----GPATPS 1004

Query: 1302 P-GRAEVERLFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPSRQVTMLPA 1360
            P G      +     + S AA  F    +G S  P+          + P+P       P 
Sbjct: 1005 PKGAPTPPAVTPPSPKGSPAATPFP---KGASTPPAA---------TPPSPKGSPAATPL 1052

Query: 1361 KQAELTRRSQAEPPHPWSPEKRPEGDRQLQGSPLPPRTSARTPERELRTQRPLESGQAGP 1420
             +   T  +   P    SP+  P     L+G+P PP  +  +P+    T  P    +  P
Sbjct: 1053 PKGAPTTPAATLP----SPKGGP-ATPSLKGAPTPPAATPPSPKGGPATPSP----KGAP 1103

Query: 1421 RQPLGVWQSQEEPPGSQG-----PHRHLERSWS----SQEGGLGPGGWWGCGEPSLGAAK 1471
              P         PP  +G     PH+    + +    S +GGL        G P+  AA 
Sbjct: 1104 MPPAAT------PPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP--PKGAPTTPAAT 1155

Query: 1472 APEGAWGGTSREYKESWGQPEAWEEKPTHELPRELGKRSPLT---SPPENWGGPAESSQS 1528
             P    G  +   K +   P A    P   L     K +P T   +PP   GG A  S  
Sbjct: 1156 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1215

Query: 1529 WHSGTPTAVGWGAEG--ACPYPRGSERRPELDWRDLL-GLLRAPGEGVWARVPSLDWEGL 1585
                TP A     +G  A P P+G+   P         G    P +G  A  P       
Sbjct: 1216 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKG--APTPPAATPPS 1273

Query: 1586 LELLQARLPRK---DPAGHRDDLARALGPELGPPGTNDVPEQESHSQPEGWAEATPVNGH 1642
            L+   A  P K   +PA       +  GP   PP     P   +   P+G +  TP    
Sbjct: 1274 LKGGLATPPHKGAPNPAVVTPPSPKG-GPATSPPKGAPTPPAATPPSPKG-SPGTPPPKG 1331

Query: 1643 SPALQSQSPVQLPSPACTSTQWPKIKVTRGPATATLAGLEQTGPLGSRSTAKGPSLPELQ 1702
            +P   + +P   PSP  T T       ++G  T   +    T P  + S   GP++    
Sbjct: 1332 APTPPAVTP---PSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAM---- 1384

Query: 1703 FQPEEPEESE--PSRGQDPLTDQKQADSADKRPA-----EGKAGSPLKGRLVTSWRMPGD 1755
              P  P+     PS   DP +      S  K PA     EG A +P KG L         
Sbjct: 1385 -TPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREG-AATPSKGDLT-------- 1434

Query: 1756 RPTLFNPFLLSLGVLRWRRPDLLNFKKGWMSILDEPGEPPSPSLTTTSTSQWKKHWFVLT 1815
             P    P  L       ++    +  KG  +     G+P  P++T  S  +      V T
Sbjct: 1435 -PPAVTPVSL-------KKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVAT 1486

Query: 1816 DSSLK 1820
             SS K
Sbjct: 1487 SSSPK 1491



 Score = 71.2 bits (173), Expect = 1e-11
 Identities = 221/973 (22%), Positives = 302/973 (31%), Gaps = 162/973 (16%)

Query: 892  PRNSSPHRTNKDIPWASFPLRPTQSDGPRTSS---PSRSK-----QSEVPWASIALRPTQ 943
            P NS   + +KD P  +    P    G  T S   P   K       E P  S+   P  
Sbjct: 837  PENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFP 896

Query: 944  GDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAP 1003
             + P T +P +        SS    +     +   +S +P    T   ++P  P+  G P
Sbjct: 897  KEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATP--PSPKGGP 954

Query: 1004 LTSPEPS---QPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESEP--PHHEPPY 1058
             T P P     PP A     +  P   SP    +  P P    P +P+  P  P  +   
Sbjct: 955  AT-PSPKWAPTPPAATPPSPKGGPATPSP----KGAPTPPAATPPSPKGGPATPSPKGAP 1009

Query: 1059 IPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRD 1118
             PPAV       P     P  T   PFP    T  A     SP+  P   P P       
Sbjct: 1010 TPPAVT-----PPSPKGSPAAT---PFPKGASTPPAATP-PSPKGSPAATPLPKGAPTTP 1060

Query: 1119 APRASSPPRQAPEPSLLFQDLPRASTES------LVPSMDSLHECPHIPTPVCIG----- 1167
            A    SP      PSL     P A+T          PS       P    P   G     
Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120

Query: 1168 -HRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLAPSTDSLHGSPVLIPQVCIGHRDAPRA 1226
             H+ AP+  +    +P+  L    P G      AP+T      P   P    G    P  
Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATPPPKG------APTT------PAATPPSPKGGLATP-- 1166

Query: 1227 SSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVLADLPPPRRLAQRQ 1286
              PP+  P+  A   PSP  G +  S   AP             T  A  PP  +     
Sbjct: 1167 --PPKGAPTTPAATPPSPKGGLATPSPKGAP-------------TTPAATPPSPKGGLAT 1211

Query: 1287 PGPQAQCSSGGRTHSPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQ 1346
            P P+   ++   T                  S   G      +G    P+          
Sbjct: 1212 PSPKGAPTTPAATPP----------------SPKGGLATPSPKGAPTTPAATPPSPKGGP 1255

Query: 1347 SSPAPSRQVTMLPAKQAELTRRSQAEPPHPWSPEKRPEGDRQLQGSPL--PPRTSARTPE 1404
            ++P P    T  PA      +   A PPH  +P          +G P   PP+ +   P 
Sbjct: 1256 ATPPPKGAPTP-PAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPA 1314

Query: 1405 RELRTQRPLESGQAGPRQPLGVWQSQEEPPGSQGPHRHLERSWSSQEGGLGPGGWWGCGE 1464
                   P   G  G   P G       PP    P                       G 
Sbjct: 1315 ----ATPPSPKGSPGTPPPKGA----PTPPAVTPPSPK--------------------GT 1346

Query: 1465 PSLGAAKAPEGAWGGTSREYKESWGQPEAWEEKPTHELPRELGKRSPLTSPPENWGGPAE 1524
            P+L A   P    G T+   KE    P A    P+H       K  P  +PP    GPA 
Sbjct: 1347 PTLPAT-TPSSKGGPTTPSSKEGPTPPAA---TPSH-------KGGPAMTPPSPKRGPAI 1395

Query: 1525 SSQSWHSGTPTAVGWGAEGACPYPRGSERRPELDWRDL-------LGLLRAPGEGV---W 1574
             S      +P  +    + A   P   E        DL       + L +AP        
Sbjct: 1396 PSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGG 1455

Query: 1575 ARVPSLDWEGLLELLQARLPRKDPAGHR--------------DDLARALGPELGPPGTND 1620
               PS   +  L  +    P++ PA  +                +     P + P    +
Sbjct: 1456 PATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKE 1515

Query: 1621 VPEQESHSQPEGWAEATPVNGHSPALQSQSPVQLPSPACTSTQWPKIKVTRGP--ATATL 1678
            VP   S  +      AT ++  +PA  +     +P PA T     K      P  A AT 
Sbjct: 1516 VPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP-PAMTVPSPKKTPAIPTPKEAPATP 1574

Query: 1679 AGLEQTGPLG-SRSTAKGPSLPELQFQPEEPEESEPSRGQDPLTDQKQADSADKRPA-EG 1736
            +  E + P   + ST KG   P+    P  P  + PS  + P        S +K PA   
Sbjct: 1575 SSKEASSPPAVTPSTYKGAPSPKELLIP--PAVTSPSPKEAPTPPAVTPPSPEKGPATPA 1632

Query: 1737 KAGSPLKGRLVTSWRMPGDRPTLFNPFLLSLGVLRWRRPDLLNFKKGWMSILDEPGEPPS 1796
              G+P    +  S     D PT        +G    +    L  KKG  + L E    P+
Sbjct: 1633 PKGTPTSPPVTPS--SLKDSPTSPASVTCKMGATVPQASKGLPAKKG-PTALKEVLVAPA 1689

Query: 1797 PSLTTTSTSQWKK 1809
            P  T   T+  +K
Sbjct: 1690 PESTPIITAPTRK 1702


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score =  103 bits (256), Expect = 3e-21
 Identities = 123/709 (17%), Positives = 270/709 (38%), Gaps = 38/709 (5%)

Query: 125  SCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGPRA 184
            S +    SD + S DS+   D+S+SS    D+ + + +                     +
Sbjct: 595  SSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDS--------------------S 634

Query: 185  DSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRSTLTQAS 244
            DS  ++ S  + S    D       D+     S+    +    +S  S +   S+ +  S
Sbjct: 635  DSDSKSDSSDSNSSDSSD--NSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS 692

Query: 245  SMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEISRASS 304
            S + +S   S +S +S +    +  +S      + S +     D+S +S +      ++S
Sbjct: 693  SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNS 752

Query: 305  TQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQDNP 364
            +    S  SS   D+  +S + + +  ++S+  N   +S+ S S+   N   SS   D+ 
Sbjct: 753  SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSND--SSNSSDSSDSSNSSDSSNSSDSS 810

Query: 365  QTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSSPNRAT 424
             +S            +     +   +S+ + ++   NS  S    D+   S + S NR+ 
Sbjct: 811  DSS----------DSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSD 860

Query: 425  RDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQR 484
              N   S    D+  +S  S ++  N +++ +  D+  +S +S  + +   N   S +  
Sbjct: 861  SSNSSDSSDSSDSSNSSDSSDSSDSNESSNSS--DSSDSSNSSDSDSSDSSNSSDS-SDS 917

Query: 485  DNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRA 544
             N   SS S  + DN  +S +   +  +  + S N +   N   S    D+  ++S + +
Sbjct: 918  SNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSS 977

Query: 545  ARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQ 604
               N + S    D+  +S +S  + ++  +  +  +   N   SS +  + ++  +S + 
Sbjct: 978  DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS 1037

Query: 605  RDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPN 664
              +  +  + S + +   N   S    D+  +S  + ++       S    D   +S  +
Sbjct: 1038 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS 1097

Query: 665  RTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSC 724
             +    +   S    D+  +S  S +    +   S    D   +S  + +++  +   S 
Sbjct: 1098 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSS 1157

Query: 725  ARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPN 784
               D+  +S  + +    +   S    D+  +S  + +    +   S    D+   SS +
Sbjct: 1158 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS-SDSSDS 1216

Query: 785  RATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDN 833
              + D+  +S +   N  + S   +   D+  +    +   SS +  D+
Sbjct: 1217 SDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDS 1265



 Score =  101 bits (252), Expect = 8e-21
 Identities = 126/669 (18%), Positives = 269/669 (40%), Gaps = 32/669 (4%)

Query: 125  SCNEDPGSDPTSSPDSATPDDTSNSS-SVDWDTVERQEEEAPSWDELAVMIPRRPREGPR 183
            S N    SD + S DS++  D+SNSS S D        E + S D               
Sbjct: 662  SSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSD------------SSD 709

Query: 184  ADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRSTLTQA 243
            +DSS  + S  + S     +      D+     S+    +    +S  S +   S+ +  
Sbjct: 710  SDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSD 769

Query: 244  SSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEISRAS 303
            SS +  S   S +S ++ +   +  + S+     ++S       D+S + S+    S  S
Sbjct: 770  SSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNS 829

Query: 304  STQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQDN 363
            S   ++S +S + + +  +  +  D    SS + ++  +S  S S+   N   SS   D+
Sbjct: 830  SDSSDSSNSSDSSDSSDSSDGSDSD----SSNRSDSSNSSDSSDSSDSSNSSDSSDSSDS 885

Query: 364  PQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSSPNRA 423
             ++S  + +    N  +     D   +S  + ++   +S  S    DN  +S +S+ + +
Sbjct: 886  NESSNSSDSSDSSN-SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS 944

Query: 424  TRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQ 483
            +  +  ++ +   N   SS S  + D+ ++  +   N   S  SS +  + D+       
Sbjct: 945  SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDS------- 997

Query: 484  RDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNR 543
             D+  +S  S ++  + +++ +   N   S  SS +  + D+  +S +   +  + S N 
Sbjct: 998  SDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1057

Query: 544  AARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTS-C 602
            +   + + S    D+  +S +S  + ++  +  ++ +   +   SS +  + D+  +S  
Sbjct: 1058 SDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1117

Query: 603  AQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASS 662
            +   N   S  SS +  + D+  +S +   +  + S + +   DS  +S +      + S
Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177

Query: 663  PNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRT 722
             N +   ++  +S    D+  +S  S +    +   S    D   +S  + ++   +   
Sbjct: 1178 SNSSDSSDSSDSS----DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNE 1233

Query: 723  SCARRDNPRAS-SRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTS 781
            S    D+  +S S N +   D+  +S +  D+   S         N   S +  D+  + 
Sbjct: 1234 SSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSD 1293

Query: 782  SPNRATRDN 790
            S N +T D+
Sbjct: 1294 S-NHSTSDD 1301



 Score = 79.3 bits (194), Expect = 4e-14
 Identities = 153/889 (17%), Positives = 318/889 (35%), Gaps = 53/889 (5%)

Query: 127  NEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSW-DELAVMIPRRPREGPRAD 185
            +E+ G+   SS +S   +   +    D D+   Q  ++  + D      P    +G +  
Sbjct: 264  DEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTS 323

Query: 186  SSQRAPSLLTRSPVGGDAAGQKKEDTGG-GGRSAGQHWARLRGESGLSLERHRSTLTQAS 244
             S+        + +  D   Q+ EDT     R + +   R+  ES    E H    +Q  
Sbjct: 324  KSEE-----NSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKES----ETHAVGKSQDK 374

Query: 245  SMT---PHSGPRSTTSQA---SPAQRDTAQ---------AASTREIPRASSPHRITQRDT 289
             +    P SG R+ T +    +  + D  Q           +  E+     P + ++   
Sbjct: 375  GIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGN 434

Query: 290  SRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRST 349
                S     S +           S Q D P +S        A+S   N       + S+
Sbjct: 435  KVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDN-------NSSS 487

Query: 350  QLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQR 409
            + D    S   +DN   S        ++  T      D   +  N     + S +   + 
Sbjct: 488  RGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKS 547

Query: 410  DNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRAT--RDNPTTSCAQRDNPRASRTS 467
            D+  +  + S N +   +   S +   N  + S S  +   D+  +  +   N   S  S
Sbjct: 548  DSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDS 607

Query: 468  SPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPR 527
            S +  + D+  +S ++ D+ ++ S S +  D+ + S     +  +  + S + +   N  
Sbjct: 608  SDSSDSSDSSDSSDSKSDSSKSESDS-SDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS 666

Query: 528  TSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRA 587
             S    D+  +SS + ++  + ++  +   N   S  SS + +  D+  +S +   N   
Sbjct: 667  DSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDS-SDSDSSDSSDSSNSNSSD 725

Query: 588  SSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDS 647
            S  + ++  + +++ +   +   S  SS +  + D+  +S +   +  + S + +   DS
Sbjct: 726  SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 785

Query: 648  PRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPR 707
              +S +      ++S + +   ++  +S +   +   SS S      +  ++ +   D  
Sbjct: 786  NDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS 845

Query: 708  ASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQEN 767
             SS    +   N      R D+  +S  + +    N   S    D+  +S+ + +    N
Sbjct: 846  DSSDGSDSDSSN------RSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSN 899

Query: 768  LRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSS 827
               S +   +  + S + +   +   S    DN  +S    ++   +       +   S+
Sbjct: 900  SSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSD-------SSDSSN 952

Query: 828  STQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHR-S 886
            S+   N   S    D+     +    + + S   D+  +S S   +   N   SS    S
Sbjct: 953  SSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1012

Query: 887  TQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPS--RSKQSEVPWASIALRPTQG 944
            +  +N  +SS    + +   +S     + S     SS S   S  S+   +S +   +  
Sbjct: 1013 SDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1072

Query: 945  DRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSS 993
                 SS S  +      S+   +  +  S  +S S +    S S  SS
Sbjct: 1073 SDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1121



 Score = 63.9 bits (154), Expect = 2e-09
 Identities = 79/412 (19%), Positives = 161/412 (39%), Gaps = 13/412 (3%)

Query: 116  EGLTTSLCGSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIP 175
            E   +S     +    SD + S +S+   D+SNSS  D        + + S D       
Sbjct: 887  ESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSS--DSSESSNSSDNSNSSDS-----S 939

Query: 176  RRPREGPRADSSQRAPSL-LTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLE 234
                    +DSS  + S   + S    D++     D+     S+    +    +S  S +
Sbjct: 940  NSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSD 999

Query: 235  RHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRAS- 293
               S+ +  SS +  S   S +S +S +   +  + S+     + S       D+S +S 
Sbjct: 1000 SSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1059

Query: 294  STQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDN 353
            S+    S  SS   ++S +S + E +  + S+       SS   ++  +S  S S+   +
Sbjct: 1060 SSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSD 1119

Query: 354  PRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPK 413
               SS   D+  +S  + +    +        D   +S  + ++   +S  S    D+  
Sbjct: 1120 SSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1179

Query: 414  ASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRAT 473
            +S +S  + ++  +  +  +   +   SS S  + D+  +S    D+  +S +S  N ++
Sbjct: 1180 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS----DSSDSSDSSDSNESS 1235

Query: 474  RDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDN 525
              +  +  +   N   SS S  + D+ + S  + D+   S   + N +  D+
Sbjct: 1236 DSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDS 1287



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 107/645 (16%), Positives = 209/645 (32%), Gaps = 47/645 (7%)

Query: 377 NPRTPCVQQDDPRASSPNRTTQRENS--RTSCAQRDNPK--ASRTSSPNRATRDNPRTSC 432
           N     VQ+D P+ +  N +T  E+     SC    N      + +S    T++   T  
Sbjct: 173 NEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPG 232

Query: 433 AQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRA--TRDNPRTSCAQRDNPRAS 490
              D    +S       +P+ + A  D    S       A   +D+   S  Q       
Sbjct: 233 TGEDAGLDNSDG-----SPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGK 287

Query: 491 SPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPT 550
                +     +   +  +P       P+    D  +TS ++ ++      N + R   T
Sbjct: 288 EDDHDSSIGQNSDSKEYYDPEGK--EDPHNEV-DGDKTSKSEENSAGIPEDNGSQRIEDT 344

Query: 551 TSCAQRDNPRASRTSSPNRATRDNPRTSC--AQRDNPRASSPNRATRDNPTTSCAQRDNP 608
                R++ R       NR T+++   +   +Q        P+   R N T    + +  
Sbjct: 345 QKLNHRESKRVE-----NRITKESETHAVGKSQDKGIEIKGPSSGNR-NITKEVGKGNEG 398

Query: 609 RASRTSSPNRATRDNPRT--------SCAQRDNPRASSPNRTTQQDSPR---------TS 651
           +  +        + N +T           Q+  P     +  T  DS             
Sbjct: 399 KEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDK 458

Query: 652 CARRDDPRA---SSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRA 708
             + DDP +   S+ N     E+   S +  D    S  S+     N   S    DD   
Sbjct: 459 SMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESK--DNGNGSDSKGAEDDDSD 516

Query: 709 SSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENL 768
           S+ +      N   +    DN ++ S        +  +S +   +  + S +      N 
Sbjct: 517 STSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNS 576

Query: 769 RTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSS 828
            +     D+  + S +  + D+  +S +   +  + S   +   D+     +     S S
Sbjct: 577 SSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDS 636

Query: 829 TQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQ 888
             + +   S +   +     +    + + S   D+  +S S   +   N   SS    + 
Sbjct: 637 DSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS 696

Query: 889 WNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQ 948
            ++  + S   ++ D   +S       SD   ++S   S  S    +S +   +      
Sbjct: 697 NSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSN---SSDSSDSSDSSNSS 753

Query: 949 TSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSS 993
            SS S  + +    S    +  +  S  +S S++  + S S  SS
Sbjct: 754 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSS 798


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score =  101 bits (251), Expect = 1e-20
 Identities = 140/732 (19%), Positives = 250/732 (34%), Gaps = 78/732 (10%)

Query: 350  QLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQR 409
            ++  P TS+TQ +   TS    T +  NPR          +  PN  T +E S T   + 
Sbjct: 98   KVTTPDTSTTQHNKVSTSPKITTAKPINPRP---------SLPPNSDTSKETSLT-VNKE 147

Query: 410  DNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTS-- 467
               +   T++ N+ T  + +         ++   + A    PT+    +  P+A  T+  
Sbjct: 148  TTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG 207

Query: 468  -------SPNRATRDNPRTSCAQRDNPRA--SSPSRATRDNPTTSCAQRDNPRASRTSSP 518
                    P   T   P ++  +   P    S+P+      PTT+   +  P   +  +P
Sbjct: 208  PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT---KSAPTTPKEPAP 264

Query: 519  NRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTS 578
                   P T       P+  +P       PTT+ +    P+    ++P +     P+  
Sbjct: 265  TTTKEPAPTT-------PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEP 317

Query: 579  CAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASS 638
                  P+  +P       PTT       P+    ++P +     P+        P+  +
Sbjct: 318  AP--TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP--TTPKEPA 373

Query: 639  PNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRT 698
            P  TT++ SP T          S+P  T ++  P T+ +    P+  SP+ T   + P  
Sbjct: 374  PT-TTKEPSPTTPKEPAPTTTKSAPT-TTKEPAPTTTKSAPTTPKEPSPTTT---KEPAP 428

Query: 699  SCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASS 758
            +  +   P        T  + P  +  +   P  + +        P  +  +   P    
Sbjct: 429  TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 488

Query: 759  PNRTIQQENLRTSCTRQDNPRT------SSPNRATRDNPRTSCAQRDNLRA----SSPIR 808
                   E L  +   +  P T      ++P   T   P           A      P  
Sbjct: 489  KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP 548

Query: 809  ATQQDNPRTCIQQNIPRS-SSTQQDNPK-TSCTKRDNLRPTCTQRDRTQSFSFQRDNPGT 866
             T ++   T  ++  P +   T    PK T+ T      PT  ++   +  +     P T
Sbjct: 549  TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA-----PTT 603

Query: 867  SSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSR 926
            +     T  +   P++P + T    P+  +P    +  P       PT    P  ++P +
Sbjct: 604  TKEPTSTTCDKPAPTTP-KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 662

Query: 927  SKQSEV-PWASIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGH 985
                E+ P  +     T  D+P  ++P   A   P + +  PT    P+  T  +  P  
Sbjct: 663  PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA--PTTPKKPAPTTPETPPP-- 718

Query: 986  QSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPR 1045
             +TS  S+P           SP+ S P  +          A   P+ L++ P     EP 
Sbjct: 719  -TTSEVSTPTTTKEPTTIHKSPDESTPELS----------AEPTPKALENSP----KEPG 763

Query: 1046 APESEPPHHEPP 1057
             P ++ P    P
Sbjct: 764  VPTTKTPAATKP 775



 Score = 97.1 bits (240), Expect = 2e-19
 Identities = 144/767 (18%), Positives = 281/767 (36%), Gaps = 102/767 (13%)

Query: 241 TQASSMTPHS----GPRSTTSQ------ASPAQRDTAQAASTREIPRASSPHRITQRDTS 290
           T  +S T H+     P+ TT++      + P   DT++  S        + ++ T  +T 
Sbjct: 101 TPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSL-------TVNKETTVETK 153

Query: 291 RASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQ 350
             ++T ++ S  +  +++T+ A  TQ  +   +S ++  P +      TP+A + ++   
Sbjct: 154 ETTTTNKQTS--TDGKEKTTSAKETQ--SIEKTSAKDLAPTSKVLAKPTPKAETTTKGPA 209

Query: 351 LDNPR--TSSTQQDNPQTS--FPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSC 406
           L  P+  T +T ++   T+   PT T  +  P TP  ++  P  +    TT +E + T+ 
Sbjct: 210 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTP--KEPAPTTTKSAPTTPKEPAPTT- 266

Query: 407 AQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRT 466
            +   P   +  +P       P T+ +    P+  +P+   +  PTT       P+    
Sbjct: 267 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT-------PKEPAP 319

Query: 467 SSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNP 526
           ++P   T   P+        P    P+  T   P  +  ++  P   +  +P       P
Sbjct: 320 TTPKEPTPTTPKEPA-----PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 374

Query: 527 RTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPR 586
            T+       +  SP       PTT+            S+P       P T+ +    P+
Sbjct: 375 TTT-------KEPSPTTPKEPAPTTT-----------KSAPTTTKEPAPTTTKSAPTTPK 416

Query: 587 ASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQD 646
             SP       PTT       P+    ++P +     P+        P+  +P  TT++ 
Sbjct: 417 EPSPTTTKEPAPTT-------PKEPAPTTPKKPAPTTPKEPAP--TTPKEPAPT-TTKKP 466

Query: 647 SPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDP 706
           +P T      +P  ++P  T      + +    +    ++P +         +    ++P
Sbjct: 467 APTTP----KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 522

Query: 707 RASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQE 766
             ++P    ++  P T  A   N        T +   P T       P  ++P  T    
Sbjct: 523 TPTTP----EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP----KEPAPTTPKETAPTT 574

Query: 767 NLRTSCTRQDNPRTSSPNR-ATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPR 825
              T+ T    P  ++P + A ++   T+  +  +     P   T +    T  ++  P 
Sbjct: 575 PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 634

Query: 826 S-SSTQQDNPK-TSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSP 883
           +        PK T+ T      PT  ++   +  +     P T+     T  +   P++P
Sbjct: 635 TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA-----PTTTKGPTSTTSDKPAPTTP 689

Query: 884 HRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQ 943
            + T    P+  +P    K  P       PT S+    S+P+ +K+            T 
Sbjct: 690 -KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSE---VSTPTTTKEP----------TTI 735

Query: 944 GDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSR 990
              P  S+P   A+  P      P +  +P+  T ++  P   +T++
Sbjct: 736 HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 782



 Score = 84.0 bits (206), Expect = 2e-15
 Identities = 144/783 (18%), Positives = 273/783 (34%), Gaps = 75/783 (9%)

Query: 29  PEEAHGARYQELRSPSGAEVPYCDLPRCPPAPEDPLSASTSGCQSVVDPGLRPGPKRGPS 88
           P+E      +E  S +  E     +   P  P++P   +T    +       P P     
Sbjct: 213 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK---EPAPTTTKE 269

Query: 89  PSAGLPEEGPTAAPRSRSRELEAVPYLEGLTTSLCGSCNEDPGSDPTSSPDSATPDDTSN 148
           P+   P+E    AP +     E  P     TT    +  ++P       P   TP + + 
Sbjct: 270 PAPTTPKE---PAPTTTK---EPAP----TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 319

Query: 149 SSSVDWDTVERQEEEAPSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAGQKK 208
           ++  +  T    +E AP+  E A   P+ P     A ++ + P+  T          +  
Sbjct: 320 TTPKE-PTPTTPKEPAPTTKEPAPTTPKEP-----APTAPKKPAPTTPKEPAPTTPKEPA 373

Query: 209 EDTGGGGRSAGQHWARLRGESGLSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQ 268
             T                E   +  +  +  T  S+ T    P  TT++++P       
Sbjct: 374 PTT--------------TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS 419

Query: 269 AASTREIPRASSPHRITQRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQED 328
             +T+E P  ++P         + + T  +   A +T +E +  ++ +   P  ++ +E 
Sbjct: 420 PTTTKE-PAPTTPKEPAPTTPKKPAPTTPK-EPAPTTPKEPAPTTTKK---PAPTTPKEP 474

Query: 329 TPRA-SSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDD 387
            P     T   TP+  +P+   +L            P+   PT TP+   P TP      
Sbjct: 475 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT-TPEEPTPTTPEEPAPT 533

Query: 388 -PRASSPNR------TTQRENSRTSCAQR--DNPKASRTSSPNRA---TRDNPRTSCAQR 435
            P+A++PN       TT +E + T+  +     PK +  ++P      T   P  +  ++
Sbjct: 534 TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK 593

Query: 436 DNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDN-PRASSPSR 494
             P+  +P+  T   PT++   +  P   + ++P       P T        P+ ++P+ 
Sbjct: 594 PAPKELAPT--TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 651

Query: 495 ATRDNPTTSCAQRDNPRA-SRTSSPNRATRDNP------RTSCAQRDNPRASSPNRAARD 547
                PTT         A + T  P   T D P       T+      P  ++P + A  
Sbjct: 652 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 711

Query: 548 NPTT---SCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQ 604
            P T   + ++   P  ++  +    + D      +    P+A   +      PTT    
Sbjct: 712 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPA 771

Query: 605 RDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPN 664
              P  + T+      RD   T       P+ +    TT +   +T+ ++         +
Sbjct: 772 ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTE---KTTESKITATTTQVTS 828

Query: 665 RTIQQENPRTSCALRDN---PRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPR 721
            T Q   P     L+     P+ ++  +TI          +   P+  + N       P+
Sbjct: 829 TTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQ 888

Query: 722 TSCARRDNPRASSRNRTIQR-DNPRTSCAQRDNPRAS---SPNRTIQQENLRTSCTRQDN 777
                   P ++ + +T+ R   P+T+   R         +P   I +  L+T+      
Sbjct: 889 KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQT 948

Query: 778 PRT 780
           P +
Sbjct: 949 PNS 951



 Score = 69.7 bits (169), Expect = 3e-11
 Identities = 161/803 (20%), Positives = 258/803 (32%), Gaps = 94/803 (11%)

Query: 628  CAQ-RDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASS 686
            CA+ +DN +    NRT ++ +P+      D+  +   N   +   P TS    +    S 
Sbjct: 63   CAEVKDNKK----NRTKKKPTPKPPVV--DEAGSGLDNGDFKVTTPDTSTTQHNKVSTSP 116

Query: 687  PSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRT 746
               T +  NPR S     D    +     ++    T      N + S+  +        T
Sbjct: 117  KITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKET 176

Query: 747  SCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSP 806
               ++ + +  +P   +  +    + T    P  ++P   T   P+   +         P
Sbjct: 177  QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPK----EP 232

Query: 807  IRATQQDNPRTCIQQ--NIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNP 864
               T +  P T  +      +S+ T    P  + TK     P  T        + +   P
Sbjct: 233  TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKE----PAPTTPKEPAPTTTKEPAP 288

Query: 865  GTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSP 924
             T+ S   T KE   P++P +      P+  +P  T    P  + P  P     P T  P
Sbjct: 289  TTTKSAPTTPKEPA-PTTPKKPAP-TTPKEPAP--TTPKEPTPTTPKEPA----PTTKEP 340

Query: 925  SRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNP- 983
            + +   E         PT   +P  ++P  PA   P + +  PT    PS  T     P 
Sbjct: 341  APTTPKEPA-------PTAPKKPAPTTPKEPAPTTPKEPA--PTTTKEPSPTTPKEPAPT 391

Query: 984  -GHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP 1042
                + + T  P       AP T  EPS                  P      +P P  P
Sbjct: 392  TTKSAPTTTKEPAPTTTKSAPTTPKEPS------------PTTTKEPAPTTPKEPAPTTP 439

Query: 1043 EPRAPESEPPHHEPPYIP--PAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQS 1100
            +  AP +  P    P  P  PA     + AP        T  +P P    T+  E    +
Sbjct: 440  KKPAPTT--PKEPAPTTPKEPAPTTTKKPAPT-------TPKEPAP----TTPKETAPTT 486

Query: 1101 PQHEPLQLPAPVCIGYRDAPRASSPPRQAP----EPSLLFQDLPRASTESLVPSMDSLHE 1156
            P+      P  +     + P  ++P   AP    EP+    + P  +T            
Sbjct: 487  PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 546

Query: 1157 CPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESL---APSTDSLHGSPVLI 1213
             P  P          P+ ++P   AP        P GT+  +L   AP+T        L 
Sbjct: 547  APTTPKEPAPTTPKEPAPTTPKETAP------TTPKGTAPTTLKEPAPTTPKKPAPKELA 600

Query: 1214 PQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVL 1273
            P               P  P          P+P +      + P G     L +E     
Sbjct: 601  PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL-KEPAPTT 659

Query: 1274 ADLPPPRRLA-QRQPGPQAQCSSGGRTHSPGRAEVERLFGQERRKSEAAGAFQAQDEGRS 1332
               P P+ LA     GP +  S      +P              K  A    +       
Sbjct: 660  PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET------APTTPKEPAPTTPKKPAPTTP 713

Query: 1333 QQPSQGQSQLLRRQSSPAPSRQVTMLPAKQAELTRRSQAEPPHPW---SPEKRPEGDRQL 1389
            + P    S++    S+P  +++ T +     E T    AEP       SP++      + 
Sbjct: 714  ETPPPTTSEV----STPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKT 769

Query: 1390 QGSPLPPRTSA---RTPERELRT 1409
              +  P  T+    +T ER+LRT
Sbjct: 770  PAATKPEMTTTAKDKTTERDLRT 792



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 107/584 (18%), Positives = 200/584 (34%), Gaps = 60/584 (10%)

Query: 42   SPSGAEVPYCDLPR--CPPAPEDPLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPT 99
            +P+  + P    P+   P  P++    +           L P     P+P+   PEE   
Sbjct: 459  APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT--PEE--- 513

Query: 100  AAPRSRSRELEAVPYLEGLTTSLCGSCN--EDPGSDPTSSPDSATPDDTSNSSSVDWDTV 157
             AP +        P     TT    + N  ++P       P   TP + + ++  +    
Sbjct: 514  LAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT 573

Query: 158  ERQEEEAPSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVG-----GDAAGQKKEDTG 212
              +     +  E A   P++P     A ++ + P+  T          G A    KE   
Sbjct: 574  TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 633

Query: 213  GGGRSAGQHWARLRGESGLSLERHRSTLTQASSM-----TPHSGPRSTTSQASPAQRDTA 267
               +         +G +  +L+    T  +  +      T   GP STTS          
Sbjct: 634  TTPKEPAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKE 691

Query: 268  QAASTREIPRASSPHRITQRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQE 327
             A +T + P  ++P +           T  E+S  ++T++ T+   S  E TP  S+  E
Sbjct: 692  TAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA--E 749

Query: 328  DTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDD 387
             TP+A       P   + +++     P  ++T +D         T +R+   TP      
Sbjct: 750  PTPKALENSPKEPGVPT-TKTPAATKPEMTTTAKDK--------TTERDLRTTPETTTAA 800

Query: 388  PRASSPNRTTQRENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRAT 447
            P+ +    TT  +                T S   AT     ++  Q   P   +  + T
Sbjct: 801  PKMTKETATTTEKT---------------TESKITATTTQVTSTTTQDTTPFKITTLKTT 845

Query: 448  RDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQR 507
               P  +  ++        + P    +   R + ++   P+   P++A +  PT++   +
Sbjct: 846  TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPK-KPTSTKKPK 904

Query: 508  DNPRASR---TSSPNRATRD----NPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPR 560
              PR  +   T +P + T      NP +  A+      + PN+           + ++  
Sbjct: 905  TMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAG 964

Query: 561  ASRTSSPNRATRDN---PRTSCAQRDNPRASSPNRATRDNPTTS 601
             +   +P+   R +   P  +      PR   PN+    NP  S
Sbjct: 965  GAEGETPHMLLRPHVFMPEVTPDMDYLPRV--PNQGIIINPMLS 1006



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 182/988 (18%), Positives = 308/988 (31%), Gaps = 148/988 (14%)

Query: 1129 APEPSLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFF 1188
            AP   +L +  P+A T +  P++ +    P  PTP        P+ ++P    P      
Sbjct: 188  APTSKVLAKPTPKAETTTKGPALTT----PKEPTPTT---PKEPASTTPKEPTPTT---I 237

Query: 1189 QDPPGTSMESLAPSTDSLHGSPVLIPQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGS 1248
            +  P T  E    +T S   +P            AP  +  P   P+     AP+ +   
Sbjct: 238  KSAPTTPKEPAPTTTKSAPTTP---------KEPAPTTTKEPA--PTTPKEPAPTTTKEP 286

Query: 1249 SGGSRGSAP--PGETRHNLEREEYTVLADLPPPRRLAQRQPGPQAQCSSGGRTHSPGRAE 1306
            +  +  SAP  P E      ++        P P     ++P P         T  P    
Sbjct: 287  APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT--TPKEPTPTTPKEPAPTTKEPAPTT 344

Query: 1307 VERLFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPSRQVTMLPAKQAELT 1366
             +       +K     A     E     P +  +    ++ SP   ++      K A  T
Sbjct: 345  PKEPAPTAPKKP----APTTPKEPAPTTPKE-PAPTTTKEPSPTTPKEPAPTTTKSAPTT 399

Query: 1367 RRSQAEPPHPWSPE--KRPEGDRQLQGSPLPPRTSARTPERELRTQRPLESGQAGPRQPL 1424
             +  A      +P   K P      + +P  P+  A T  ++     P E     P++P 
Sbjct: 400  TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 459

Query: 1425 GVWQSQEEP--PGSQGPHRHLERSWSSQEGGLGPGGWWGCGEPSLGAAKAPEGAWGGTSR 1482
                 +  P  P    P    E + ++ +  L P        P   A   PE     T  
Sbjct: 460  PTTTKKPAPTTPKEPAPTTPKETAPTTPKK-LTPT------TPEKLAPTTPEKPAPTTPE 512

Query: 1483 EYKESWGQPEAWEEKPTHELPRELGKRSPLTSPPENWGGPAESSQSWHSGTPT---AVGW 1539
            E   +        E+PT   P E    +P  + P     PA ++    + T     A   
Sbjct: 513  ELAPTT------PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 566

Query: 1540 GAEGACPYPRGSERRPELDWRDLLGLLRAPGEGVWARVPSLDWEGLLELLQARLPRKDPA 1599
              E A   P+G+                AP                       L    P 
Sbjct: 567  PKETAPTTPKGT----------------AP---------------------TTLKEPAPT 589

Query: 1600 GHRDDLARALGPELGPPGTNDVPEQESHSQPEGWAEATPVNGHSPALQSQSPVQLPSPAC 1659
              +    + L P      T+   ++ + + P+G A  TP        +  +P      A 
Sbjct: 590  TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 649

Query: 1660 TSTQWPKIKVTRGPATATLAGLEQTGPLGSRSTAKGPSLPELQFQPEEPEESEPSRGQDP 1719
            T+ + P     + PA   LA     GP  + S    P+ P+ +  P  P+E  P+  + P
Sbjct: 650  TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK-ETAPTTPKEPAPTTPKKP 708

Query: 1720 LTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDRPTLFNPFLLSLGVLRWRRPDLL- 1778
                 +       P   +  +P   +  T+     D  T                P+L  
Sbjct: 709  APTTPETPP----PTTSEVSTPTTTKEPTTIHKSPDEST----------------PELSA 748

Query: 1779 -NFKKGWMSILDEPGEPPS-------PSLTTTSTSQWKKHWFVLTDSSLKYYRDSTAEEA 1830
                K   +   EPG P +       P +TTT+  +  +     T  +       T E A
Sbjct: 749  EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETA 808

Query: 1831 DELDGEIDLR---SCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTVR 1887
               +   + +   + T VT    Q    F+I T         +T+          +KT+ 
Sbjct: 809  TTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTT---------TKKTIT 859

Query: 1888 PTSAPDVTKLSDSNKENALHSYSTQKGPLKAGEQRAGSEVISRGGPRKADGQRQALDYVE 1947
             T   +  + +   K+ A +S +T   P K               P KA  +  +    +
Sbjct: 860  TTEIMNKPEETAKPKDRATNSKATTPKPQK---------------PTKAPKKPTSTKKPK 904

Query: 1948 LSPLTQASPQRARTPARTPDRLAKQEELERDLAQRSEERRKWFEATDSRTPEV-PAGEGP 2006
              P  +  P+   TP +    + +     R      +   +  +  +S+  EV P  E  
Sbjct: 905  TMPRVR-KPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDA 963

Query: 2007 RRGLGAPLTEDQQNRLSEEIEKKWQELEKLPLRENKRVPLTALLNQSRGERRGPPSDGHE 2066
                G   T     R    + +   +++ LP   N+ + +  +L+       G P DG  
Sbjct: 964  GGAEGE--TPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETNICNGKPVDGLT 1021

Query: 2067 ALEKEVQALRAQLEAWRLQGEAPQSALR 2094
             L             W L   +P S  R
Sbjct: 1022 TLRNGTLVAFRGHYFWMLSPFSPPSPAR 1049



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 84/433 (19%), Positives = 142/433 (32%), Gaps = 69/433 (15%)

Query: 1325 QAQDEGRSQQPSQGQSQLLRRQSSP--APSRQVTMLPAKQAELTRRSQA----EPPHPWS 1378
            Q   +G+ +  S  ++Q + + S+   AP+ +V   P  +AE T +  A    + P P +
Sbjct: 161  QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT 220

Query: 1379 PEKRPEGDRQLQGSPLPPRTSARTPERELRTQRPLESGQAGPRQPLGVWQSQEEPPGSQG 1438
            P K P      + +P   +++  TP+    T    +S    P++P      +  P   + 
Sbjct: 221  P-KEPASTTPKEPTPTTIKSAPTTPKEPAPTTT--KSAPTTPKEPAPTTTKEPAPTTPKE 277

Query: 1439 PHRHLERSWSSQEGGLGPGGWWGCGEPSLGAAKAPEGAWGGTSREYKESWGQPEAWEEKP 1498
            P                         P+     AP       +   + +   P+    KP
Sbjct: 278  P------------------------APTTTKEPAPTTTKSAPTTPKEPAPTTPK----KP 309

Query: 1499 THELPRELGKRSPLTSPPENWGGPAESSQSWHSGTPTAVGWGAEGACPYPRGSERRPELD 1558
                P+E    +P    P     PA +++     TP           P P   ++     
Sbjct: 310  APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE---------PAPTAPKKPAPTT 360

Query: 1559 WRDLLGLLRAPGEGVWARVPSLDWEGLLELLQARLPRKDPAGHRDDLARALGPELGPPGT 1618
             ++              + PS                K+PA      A     E  P  T
Sbjct: 361  PKEPAPTTPKEPAPTTTKEPS------------PTTPKEPAPTTTKSAPTTTKEPAPTTT 408

Query: 1619 NDVPEQESHSQPEGWAEATPVNGHSPAL---QSQSPVQLPSPACTSTQWPKIKVTRGPAT 1675
               P       P    E  P     PA    +  +P     PA T+ + P    T+ PA 
Sbjct: 409  KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 468

Query: 1676 ATLAGLEQTGPLGSRSTAK---GPSLPELQFQPEEPEESEPSRGQD--PLTDQKQADSAD 1730
             T      T P  +  T      P+ PE +  P  PE+  P+  ++  P T ++   +  
Sbjct: 469  TTPKEPAPTTPKETAPTTPKKLTPTTPE-KLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 527

Query: 1731 KRPA--EGKAGSP 1741
            + PA    KA +P
Sbjct: 528  EEPAPTTPKAAAP 540


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score =  101 bits (251), Expect = 1e-20
 Identities = 140/732 (19%), Positives = 250/732 (34%), Gaps = 78/732 (10%)

Query: 350  QLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQR 409
            ++  P TS+TQ +   TS    T +  NPR          +  PN  T +E S T   + 
Sbjct: 139  KVTTPDTSTTQHNKVSTSPKITTAKPINPRP---------SLPPNSDTSKETSLT-VNKE 188

Query: 410  DNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTS-- 467
               +   T++ N+ T  + +         ++   + A    PT+    +  P+A  T+  
Sbjct: 189  TTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG 248

Query: 468  -------SPNRATRDNPRTSCAQRDNPRA--SSPSRATRDNPTTSCAQRDNPRASRTSSP 518
                    P   T   P ++  +   P    S+P+      PTT+   +  P   +  +P
Sbjct: 249  PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT---KSAPTTPKEPAP 305

Query: 519  NRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTS 578
                   P T       P+  +P       PTT+ +    P+    ++P +     P+  
Sbjct: 306  TTTKEPAPTT-------PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEP 358

Query: 579  CAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASS 638
                  P+  +P       PTT       P+    ++P +     P+        P+  +
Sbjct: 359  AP--TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP--TTPKEPA 414

Query: 639  PNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRT 698
            P  TT++ SP T          S+P  T ++  P T+ +    P+  SP+ T   + P  
Sbjct: 415  PT-TTKEPSPTTPKEPAPTTTKSAPT-TTKEPAPTTTKSAPTTPKEPSPTTT---KEPAP 469

Query: 699  SCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASS 758
            +  +   P        T  + P  +  +   P  + +        P  +  +   P    
Sbjct: 470  TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 529

Query: 759  PNRTIQQENLRTSCTRQDNPRT------SSPNRATRDNPRTSCAQRDNLRA----SSPIR 808
                   E L  +   +  P T      ++P   T   P           A      P  
Sbjct: 530  KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP 589

Query: 809  ATQQDNPRTCIQQNIPRS-SSTQQDNPK-TSCTKRDNLRPTCTQRDRTQSFSFQRDNPGT 866
             T ++   T  ++  P +   T    PK T+ T      PT  ++   +  +     P T
Sbjct: 590  TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA-----PTT 644

Query: 867  SSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSR 926
            +     T  +   P++P + T    P+  +P    +  P       PT    P  ++P +
Sbjct: 645  TKEPTSTTCDKPAPTTP-KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 703

Query: 927  SKQSEV-PWASIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGH 985
                E+ P  +     T  D+P  ++P   A   P + +  PT    P+  T  +  P  
Sbjct: 704  PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA--PTTPKKPAPTTPETPPP-- 759

Query: 986  QSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPR 1045
             +TS  S+P           SP+ S P  +          A   P+ L++ P     EP 
Sbjct: 760  -TTSEVSTPTTTKEPTTIHKSPDESTPELS----------AEPTPKALENSP----KEPG 804

Query: 1046 APESEPPHHEPP 1057
             P ++ P    P
Sbjct: 805  VPTTKTPAATKP 816



 Score = 97.1 bits (240), Expect = 2e-19
 Identities = 144/767 (18%), Positives = 281/767 (36%), Gaps = 102/767 (13%)

Query: 241 TQASSMTPHS----GPRSTTSQ------ASPAQRDTAQAASTREIPRASSPHRITQRDTS 290
           T  +S T H+     P+ TT++      + P   DT++  S        + ++ T  +T 
Sbjct: 142 TPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSL-------TVNKETTVETK 194

Query: 291 RASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQ 350
             ++T ++ S  +  +++T+ A  TQ  +   +S ++  P +      TP+A + ++   
Sbjct: 195 ETTTTNKQTS--TDGKEKTTSAKETQ--SIEKTSAKDLAPTSKVLAKPTPKAETTTKGPA 250

Query: 351 LDNPR--TSSTQQDNPQTS--FPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSC 406
           L  P+  T +T ++   T+   PT T  +  P TP  ++  P  +    TT +E + T+ 
Sbjct: 251 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTP--KEPAPTTTKSAPTTPKEPAPTT- 307

Query: 407 AQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRT 466
            +   P   +  +P       P T+ +    P+  +P+   +  PTT       P+    
Sbjct: 308 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT-------PKEPAP 360

Query: 467 SSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNP 526
           ++P   T   P+        P    P+  T   P  +  ++  P   +  +P       P
Sbjct: 361 TTPKEPTPTTPKEPA-----PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 415

Query: 527 RTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPR 586
            T+       +  SP       PTT+            S+P       P T+ +    P+
Sbjct: 416 TTT-------KEPSPTTPKEPAPTTT-----------KSAPTTTKEPAPTTTKSAPTTPK 457

Query: 587 ASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQD 646
             SP       PTT       P+    ++P +     P+        P+  +P  TT++ 
Sbjct: 458 EPSPTTTKEPAPTT-------PKEPAPTTPKKPAPTTPKEPAP--TTPKEPAPT-TTKKP 507

Query: 647 SPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDP 706
           +P T      +P  ++P  T      + +    +    ++P +         +    ++P
Sbjct: 508 APTTP----KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 563

Query: 707 RASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQE 766
             ++P    ++  P T  A   N        T +   P T       P  ++P  T    
Sbjct: 564 TPTTP----EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP----KEPAPTTPKETAPTT 615

Query: 767 NLRTSCTRQDNPRTSSPNR-ATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPR 825
              T+ T    P  ++P + A ++   T+  +  +     P   T +    T  ++  P 
Sbjct: 616 PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 675

Query: 826 S-SSTQQDNPK-TSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSP 883
           +        PK T+ T      PT  ++   +  +     P T+     T  +   P++P
Sbjct: 676 TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA-----PTTTKGPTSTTSDKPAPTTP 730

Query: 884 HRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQ 943
            + T    P+  +P    K  P       PT S+    S+P+ +K+            T 
Sbjct: 731 -KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSE---VSTPTTTKEP----------TTI 776

Query: 944 GDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSR 990
              P  S+P   A+  P      P +  +P+  T ++  P   +T++
Sbjct: 777 HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 823



 Score = 84.0 bits (206), Expect = 2e-15
 Identities = 144/783 (18%), Positives = 273/783 (34%), Gaps = 75/783 (9%)

Query: 29  PEEAHGARYQELRSPSGAEVPYCDLPRCPPAPEDPLSASTSGCQSVVDPGLRPGPKRGPS 88
           P+E      +E  S +  E     +   P  P++P   +T    +       P P     
Sbjct: 254 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK---EPAPTTTKE 310

Query: 89  PSAGLPEEGPTAAPRSRSRELEAVPYLEGLTTSLCGSCNEDPGSDPTSSPDSATPDDTSN 148
           P+   P+E    AP +     E  P     TT    +  ++P       P   TP + + 
Sbjct: 311 PAPTTPKE---PAPTTTK---EPAP----TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 360

Query: 149 SSSVDWDTVERQEEEAPSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAGQKK 208
           ++  +  T    +E AP+  E A   P+ P     A ++ + P+  T          +  
Sbjct: 361 TTPKE-PTPTTPKEPAPTTKEPAPTTPKEP-----APTAPKKPAPTTPKEPAPTTPKEPA 414

Query: 209 EDTGGGGRSAGQHWARLRGESGLSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQ 268
             T                E   +  +  +  T  S+ T    P  TT++++P       
Sbjct: 415 PTT--------------TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPS 460

Query: 269 AASTREIPRASSPHRITQRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQED 328
             +T+E P  ++P         + + T  +   A +T +E +  ++ +   P  ++ +E 
Sbjct: 461 PTTTKE-PAPTTPKEPAPTTPKKPAPTTPK-EPAPTTPKEPAPTTTKK---PAPTTPKEP 515

Query: 329 TPRA-SSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDD 387
            P     T   TP+  +P+   +L            P+   PT TP+   P TP      
Sbjct: 516 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT-TPEEPTPTTPEEPAPT 574

Query: 388 -PRASSPNR------TTQRENSRTSCAQR--DNPKASRTSSPNRA---TRDNPRTSCAQR 435
            P+A++PN       TT +E + T+  +     PK +  ++P      T   P  +  ++
Sbjct: 575 TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK 634

Query: 436 DNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDN-PRASSPSR 494
             P+  +P+  T   PT++   +  P   + ++P       P T        P+ ++P+ 
Sbjct: 635 PAPKELAPT--TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTT 692

Query: 495 ATRDNPTTSCAQRDNPRA-SRTSSPNRATRDNP------RTSCAQRDNPRASSPNRAARD 547
                PTT         A + T  P   T D P       T+      P  ++P + A  
Sbjct: 693 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 752

Query: 548 NPTT---SCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQ 604
            P T   + ++   P  ++  +    + D      +    P+A   +      PTT    
Sbjct: 753 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPA 812

Query: 605 RDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPN 664
              P  + T+      RD   T       P+ +    TT +   +T+ ++         +
Sbjct: 813 ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTE---KTTESKITATTTQVTS 869

Query: 665 RTIQQENPRTSCALRDN---PRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPR 721
            T Q   P     L+     P+ ++  +TI          +   P+  + N       P+
Sbjct: 870 TTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQ 929

Query: 722 TSCARRDNPRASSRNRTIQR-DNPRTSCAQRDNPRAS---SPNRTIQQENLRTSCTRQDN 777
                   P ++ + +T+ R   P+T+   R         +P   I +  L+T+      
Sbjct: 930 KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQT 989

Query: 778 PRT 780
           P +
Sbjct: 990 PNS 992



 Score = 69.7 bits (169), Expect = 3e-11
 Identities = 161/803 (20%), Positives = 258/803 (32%), Gaps = 94/803 (11%)

Query: 628  CAQ-RDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASS 686
            CA+ +DN +    NRT ++ +P+      D+  +   N   +   P TS    +    S 
Sbjct: 104  CAEVKDNKK----NRTKKKPTPKPPVV--DEAGSGLDNGDFKVTTPDTSTTQHNKVSTSP 157

Query: 687  PSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRT 746
               T +  NPR S     D    +     ++    T      N + S+  +        T
Sbjct: 158  KITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKET 217

Query: 747  SCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSP 806
               ++ + +  +P   +  +    + T    P  ++P   T   P+   +         P
Sbjct: 218  QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPK----EP 273

Query: 807  IRATQQDNPRTCIQQ--NIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNP 864
               T +  P T  +      +S+ T    P  + TK     P  T        + +   P
Sbjct: 274  TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKE----PAPTTPKEPAPTTTKEPAP 329

Query: 865  GTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSP 924
             T+ S   T KE   P++P +      P+  +P  T    P  + P  P     P T  P
Sbjct: 330  TTTKSAPTTPKEPA-PTTPKKPAP-TTPKEPAP--TTPKEPTPTTPKEPA----PTTKEP 381

Query: 925  SRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNP- 983
            + +   E         PT   +P  ++P  PA   P + +  PT    PS  T     P 
Sbjct: 382  APTTPKEPA-------PTAPKKPAPTTPKEPAPTTPKEPA--PTTTKEPSPTTPKEPAPT 432

Query: 984  -GHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFP 1042
                + + T  P       AP T  EPS                  P      +P P  P
Sbjct: 433  TTKSAPTTTKEPAPTTTKSAPTTPKEPS------------PTTTKEPAPTTPKEPAPTTP 480

Query: 1043 EPRAPESEPPHHEPPYIP--PAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQS 1100
            +  AP +  P    P  P  PA     + AP        T  +P P    T+  E    +
Sbjct: 481  KKPAPTT--PKEPAPTTPKEPAPTTTKKPAPT-------TPKEPAP----TTPKETAPTT 527

Query: 1101 PQHEPLQLPAPVCIGYRDAPRASSPPRQAP----EPSLLFQDLPRASTESLVPSMDSLHE 1156
            P+      P  +     + P  ++P   AP    EP+    + P  +T            
Sbjct: 528  PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 587

Query: 1157 CPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESL---APSTDSLHGSPVLI 1213
             P  P          P+ ++P   AP        P GT+  +L   AP+T        L 
Sbjct: 588  APTTPKEPAPTTPKEPAPTTPKETAP------TTPKGTAPTTLKEPAPTTPKKPAPKELA 641

Query: 1214 PQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVL 1273
            P               P  P          P+P +      + P G     L +E     
Sbjct: 642  PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL-KEPAPTT 700

Query: 1274 ADLPPPRRLA-QRQPGPQAQCSSGGRTHSPGRAEVERLFGQERRKSEAAGAFQAQDEGRS 1332
               P P+ LA     GP +  S      +P              K  A    +       
Sbjct: 701  PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET------APTTPKEPAPTTPKKPAPTTP 754

Query: 1333 QQPSQGQSQLLRRQSSPAPSRQVTMLPAKQAELTRRSQAEPPHPW---SPEKRPEGDRQL 1389
            + P    S++    S+P  +++ T +     E T    AEP       SP++      + 
Sbjct: 755  ETPPPTTSEV----STPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKT 810

Query: 1390 QGSPLPPRTSA---RTPERELRT 1409
              +  P  T+    +T ER+LRT
Sbjct: 811  PAATKPEMTTTAKDKTTERDLRT 833



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 107/584 (18%), Positives = 200/584 (34%), Gaps = 60/584 (10%)

Query: 42   SPSGAEVPYCDLPR--CPPAPEDPLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPT 99
            +P+  + P    P+   P  P++    +           L P     P+P+   PEE   
Sbjct: 500  APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT--PEE--- 554

Query: 100  AAPRSRSRELEAVPYLEGLTTSLCGSCN--EDPGSDPTSSPDSATPDDTSNSSSVDWDTV 157
             AP +        P     TT    + N  ++P       P   TP + + ++  +    
Sbjct: 555  LAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPT 614

Query: 158  ERQEEEAPSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVG-----GDAAGQKKEDTG 212
              +     +  E A   P++P     A ++ + P+  T          G A    KE   
Sbjct: 615  TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 674

Query: 213  GGGRSAGQHWARLRGESGLSLERHRSTLTQASSM-----TPHSGPRSTTSQASPAQRDTA 267
               +         +G +  +L+    T  +  +      T   GP STTS          
Sbjct: 675  TTPKEPAP--TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKE 732

Query: 268  QAASTREIPRASSPHRITQRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQE 327
             A +T + P  ++P +           T  E+S  ++T++ T+   S  E TP  S+  E
Sbjct: 733  TAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA--E 790

Query: 328  DTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDD 387
             TP+A       P   + +++     P  ++T +D         T +R+   TP      
Sbjct: 791  PTPKALENSPKEPGVPT-TKTPAATKPEMTTTAKDK--------TTERDLRTTPETTTAA 841

Query: 388  PRASSPNRTTQRENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRAT 447
            P+ +    TT  +                T S   AT     ++  Q   P   +  + T
Sbjct: 842  PKMTKETATTTEKT---------------TESKITATTTQVTSTTTQDTTPFKITTLKTT 886

Query: 448  RDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQR 507
               P  +  ++        + P    +   R + ++   P+   P++A +  PT++   +
Sbjct: 887  TLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPK-KPTSTKKPK 945

Query: 508  DNPRASR---TSSPNRATRD----NPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPR 560
              PR  +   T +P + T      NP +  A+      + PN+           + ++  
Sbjct: 946  TMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAG 1005

Query: 561  ASRTSSPNRATRDN---PRTSCAQRDNPRASSPNRATRDNPTTS 601
             +   +P+   R +   P  +      PR   PN+    NP  S
Sbjct: 1006 GAEGETPHMLLRPHVFMPEVTPDMDYLPRV--PNQGIIINPMLS 1047



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 182/988 (18%), Positives = 308/988 (31%), Gaps = 148/988 (14%)

Query: 1129 APEPSLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFF 1188
            AP   +L +  P+A T +  P++ +    P  PTP        P+ ++P    P      
Sbjct: 229  APTSKVLAKPTPKAETTTKGPALTT----PKEPTPTT---PKEPASTTPKEPTPTT---I 278

Query: 1189 QDPPGTSMESLAPSTDSLHGSPVLIPQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGS 1248
            +  P T  E    +T S   +P            AP  +  P   P+     AP+ +   
Sbjct: 279  KSAPTTPKEPAPTTTKSAPTTP---------KEPAPTTTKEPA--PTTPKEPAPTTTKEP 327

Query: 1249 SGGSRGSAP--PGETRHNLEREEYTVLADLPPPRRLAQRQPGPQAQCSSGGRTHSPGRAE 1306
            +  +  SAP  P E      ++        P P     ++P P         T  P    
Sbjct: 328  APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT--TPKEPTPTTPKEPAPTTKEPAPTT 385

Query: 1307 VERLFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPSRQVTMLPAKQAELT 1366
             +       +K     A     E     P +  +    ++ SP   ++      K A  T
Sbjct: 386  PKEPAPTAPKKP----APTTPKEPAPTTPKE-PAPTTTKEPSPTTPKEPAPTTTKSAPTT 440

Query: 1367 RRSQAEPPHPWSPE--KRPEGDRQLQGSPLPPRTSARTPERELRTQRPLESGQAGPRQPL 1424
             +  A      +P   K P      + +P  P+  A T  ++     P E     P++P 
Sbjct: 441  TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 500

Query: 1425 GVWQSQEEP--PGSQGPHRHLERSWSSQEGGLGPGGWWGCGEPSLGAAKAPEGAWGGTSR 1482
                 +  P  P    P    E + ++ +  L P        P   A   PE     T  
Sbjct: 501  PTTTKKPAPTTPKEPAPTTPKETAPTTPKK-LTPT------TPEKLAPTTPEKPAPTTPE 553

Query: 1483 EYKESWGQPEAWEEKPTHELPRELGKRSPLTSPPENWGGPAESSQSWHSGTPT---AVGW 1539
            E   +        E+PT   P E    +P  + P     PA ++    + T     A   
Sbjct: 554  ELAPTT------PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 607

Query: 1540 GAEGACPYPRGSERRPELDWRDLLGLLRAPGEGVWARVPSLDWEGLLELLQARLPRKDPA 1599
              E A   P+G+                AP                       L    P 
Sbjct: 608  PKETAPTTPKGT----------------AP---------------------TTLKEPAPT 630

Query: 1600 GHRDDLARALGPELGPPGTNDVPEQESHSQPEGWAEATPVNGHSPALQSQSPVQLPSPAC 1659
              +    + L P      T+   ++ + + P+G A  TP        +  +P      A 
Sbjct: 631  TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 690

Query: 1660 TSTQWPKIKVTRGPATATLAGLEQTGPLGSRSTAKGPSLPELQFQPEEPEESEPSRGQDP 1719
            T+ + P     + PA   LA     GP  + S    P+ P+ +  P  P+E  P+  + P
Sbjct: 691  TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK-ETAPTTPKEPAPTTPKKP 749

Query: 1720 LTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDRPTLFNPFLLSLGVLRWRRPDLL- 1778
                 +       P   +  +P   +  T+     D  T                P+L  
Sbjct: 750  APTTPETPP----PTTSEVSTPTTTKEPTTIHKSPDEST----------------PELSA 789

Query: 1779 -NFKKGWMSILDEPGEPPS-------PSLTTTSTSQWKKHWFVLTDSSLKYYRDSTAEEA 1830
                K   +   EPG P +       P +TTT+  +  +     T  +       T E A
Sbjct: 790  EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETA 849

Query: 1831 DELDGEIDLR---SCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTVR 1887
               +   + +   + T VT    Q    F+I T         +T+          +KT+ 
Sbjct: 850  TTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTT---------TKKTIT 900

Query: 1888 PTSAPDVTKLSDSNKENALHSYSTQKGPLKAGEQRAGSEVISRGGPRKADGQRQALDYVE 1947
             T   +  + +   K+ A +S +T   P K               P KA  +  +    +
Sbjct: 901  TTEIMNKPEETAKPKDRATNSKATTPKPQK---------------PTKAPKKPTSTKKPK 945

Query: 1948 LSPLTQASPQRARTPARTPDRLAKQEELERDLAQRSEERRKWFEATDSRTPEV-PAGEGP 2006
              P  +  P+   TP +    + +     R      +   +  +  +S+  EV P  E  
Sbjct: 946  TMPRVR-KPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDA 1004

Query: 2007 RRGLGAPLTEDQQNRLSEEIEKKWQELEKLPLRENKRVPLTALLNQSRGERRGPPSDGHE 2066
                G   T     R    + +   +++ LP   N+ + +  +L+       G P DG  
Sbjct: 1005 GGAEGE--TPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETNICNGKPVDGLT 1062

Query: 2067 ALEKEVQALRAQLEAWRLQGEAPQSALR 2094
             L             W L   +P S  R
Sbjct: 1063 TLRNGTLVAFRGHYFWMLSPFSPPSPAR 1090



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 84/433 (19%), Positives = 142/433 (32%), Gaps = 69/433 (15%)

Query: 1325 QAQDEGRSQQPSQGQSQLLRRQSSP--APSRQVTMLPAKQAELTRRSQA----EPPHPWS 1378
            Q   +G+ +  S  ++Q + + S+   AP+ +V   P  +AE T +  A    + P P +
Sbjct: 202  QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT 261

Query: 1379 PEKRPEGDRQLQGSPLPPRTSARTPERELRTQRPLESGQAGPRQPLGVWQSQEEPPGSQG 1438
            P K P      + +P   +++  TP+    T    +S    P++P      +  P   + 
Sbjct: 262  P-KEPASTTPKEPTPTTIKSAPTTPKEPAPTTT--KSAPTTPKEPAPTTTKEPAPTTPKE 318

Query: 1439 PHRHLERSWSSQEGGLGPGGWWGCGEPSLGAAKAPEGAWGGTSREYKESWGQPEAWEEKP 1498
            P                         P+     AP       +   + +   P+    KP
Sbjct: 319  P------------------------APTTTKEPAPTTTKSAPTTPKEPAPTTPK----KP 350

Query: 1499 THELPRELGKRSPLTSPPENWGGPAESSQSWHSGTPTAVGWGAEGACPYPRGSERRPELD 1558
                P+E    +P    P     PA +++     TP           P P   ++     
Sbjct: 351  APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE---------PAPTAPKKPAPTT 401

Query: 1559 WRDLLGLLRAPGEGVWARVPSLDWEGLLELLQARLPRKDPAGHRDDLARALGPELGPPGT 1618
             ++              + PS                K+PA      A     E  P  T
Sbjct: 402  PKEPAPTTPKEPAPTTTKEPS------------PTTPKEPAPTTTKSAPTTTKEPAPTTT 449

Query: 1619 NDVPEQESHSQPEGWAEATPVNGHSPAL---QSQSPVQLPSPACTSTQWPKIKVTRGPAT 1675
               P       P    E  P     PA    +  +P     PA T+ + P    T+ PA 
Sbjct: 450  KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 509

Query: 1676 ATLAGLEQTGPLGSRSTAK---GPSLPELQFQPEEPEESEPSRGQD--PLTDQKQADSAD 1730
             T      T P  +  T      P+ PE +  P  PE+  P+  ++  P T ++   +  
Sbjct: 510  TTPKEPAPTTPKETAPTTPKKLTPTTPE-KLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 568

Query: 1731 KRPA--EGKAGSP 1741
            + PA    KA +P
Sbjct: 569  EEPAPTTPKAAAP 581


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score =  100 bits (248), Expect = 2e-20
 Identities = 177/741 (23%), Positives = 290/741 (39%), Gaps = 102/741 (13%)

Query: 283 RITQRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRA 342
           +I Q   +      ++  +    ++E+SR    +  +PR   ++  +PR  S+     R 
Sbjct: 135 QIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERK 194

Query: 343 SSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENS 402
            S SRS +    RT S          P+  P+++  +TP + +   +   P+       S
Sbjct: 195 RSHSRSPR---HRTKSRS--------PSPAPEKKE-KTPELPEPSVKVKEPSVQEATSTS 242

Query: 403 RTSCAQRDNP--KASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDN 460
                 +  P  +    S    + ++  +     R   R+ S SR    +P+ +  +R +
Sbjct: 243 DILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRH 302

Query: 461 PRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNR 520
              SR+ SP R  R +PR    +R +PR  +P R  R  P         PR  R+ SP R
Sbjct: 303 RSRSRSYSPRR--RPSPR----RRPSPRRRTPPR--RMPPP--------PRHRRSRSPVR 346

Query: 521 ATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPR--ASRTSSPNRATRDNPRTS 578
             R   R+S +   +  +SS +R+           R  P+    RTSSP R TR    ++
Sbjct: 347 RRR---RSSASLSGSSSSSSSSRS-----------RSPPKKPPKRTSSPPRKTRRLSPSA 392

Query: 579 CAQRDNPRAS---SPNRATRDNPTTSCAQRDNPRASRTS-SPNRAT-RDNPRTSCAQRDN 633
              R   R S   +P   TR +PT    Q +  R SR S SP R + +        +R++
Sbjct: 393 SPPRRRHRPSPPATPPPKTRHSPTPQ--QSNRTRKSRVSVSPGRTSGKVTKHKGTEKRES 450

Query: 634 PR-ASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASS-----P 687
           P  A  P +    +S      +     +    R  +++N ++S    D+  +SS     P
Sbjct: 451 PSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSS---SDSGSSSSSEDERP 507

Query: 688 SRTIQQENPRTSCAQRDDPRAS---SPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNP 744
            R+   +N      +R  P  S   SP +  ++ +PR    R  +P  + R R+    +P
Sbjct: 508 KRS-HVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRS---PSP 563

Query: 745 RTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRAS 804
                +R  P      RT      R    R  +PR  SP    R +P     +R      
Sbjct: 564 APPPRRRRTPTPPPRRRTPSPPPRR----RSPSPRRYSPPIQRRYSPSPPPKRRTASPPP 619

Query: 805 SP-IRATQQDNPRTCIQQNIP---RSSS-TQQDNPKTSCTKRDNLRPTCTQRDRTQSFSF 859
            P  RA+    P+  +  + P   RSS  T++ +P  S   R    P+ + R+       
Sbjct: 620 PPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPN 679

Query: 860 QRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNPR---NSSPHRTNKDIPWASFPLRPTQS 916
           +R +P              RP +P  S+     R   +SSP R     P ++ P+R    
Sbjct: 680 KRHSPSP------------RPRAPQTSSSPPPVRRGASSSPQRRQSPSP-STRPIRRVS- 725

Query: 917 DGPRTSSPSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRA 976
              RT  P + K++  P +  ++R     R  + SP  PA   PP     P Q   PS  
Sbjct: 726 ---RTPEPKKIKKAASP-SPQSVRRVSSSRSVSGSP-EPAAKKPPAPP-SPVQSQSPSTN 779

Query: 977 TSSSHNPGHQSTSRTSSPVYP 997
            S +  P  ++ S T SP  P
Sbjct: 780 WSPA-VPVKKAKSPTPSPSPP 799



 Score = 97.1 bits (240), Expect = 2e-19
 Identities = 151/692 (21%), Positives = 250/692 (36%), Gaps = 79/692 (11%)

Query: 445  RATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSC 504
            R        S  ++D  +  R      ++R+    S + R   ++ SPS   R +P    
Sbjct: 134  RQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRR-KSRSPSPRRRSSPVRRE 192

Query: 505  AQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQ-------RD 557
             +R + R+ R  + +R+    P       + P  S   +       TS +          
Sbjct: 193  RKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEP 252

Query: 558  NPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPN 617
             P     S    + ++  +     R   R+ S +R    +P+ +  +R +   SR+ SP 
Sbjct: 253  IPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPR 312

Query: 618  RATRDNPRTSCAQRDNPRASSP-----------------------NRTTQQDSPRTSCAR 654
            R      R S  +R  PR   P                       + ++   S   S  +
Sbjct: 313  RRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPK 372

Query: 655  RDDPRASSPNRTIQQENPRTSCAL---RDNPRASSPSRTIQQENPRTSCAQRDDPRASSP 711
            +   R SSP R  ++ +P  S      R +P A+ P +T     P+ S   R    + SP
Sbjct: 373  KPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSP 432

Query: 712  NRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTS 771
             RT+ +        +R++P  + + R ++      S ++ D     +   ++QQ      
Sbjct: 433  GRTSGKVTKHKGTEKRESPSPAPKPRKVE-----LSESEEDKGGKMAAADSVQQRRQYRR 487

Query: 772  CTRQDNPRTSSPNRATRDNPRTSCAQRDNL---RASSPIRATQQDNPRTCIQQNIPRSSS 828
              +Q +  + S + +  + P+ S  +   +   R  SP R+    +PR   ++  PR   
Sbjct: 488  QNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSA-SPSPRKRQKETSPRGRR 546

Query: 829  TQQDNPKTSCTKRD---------NLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLR 879
             +  +P  +  +R             PT   R RT S   +R +P         Q+    
Sbjct: 547  RRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSP 606

Query: 880  PSSPHRSTQWNNP---RNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWAS 936
               P R T    P   R +SP    K     S P  P Q   P T   S S  S+    S
Sbjct: 607  SPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPP--PKQRSSPVTKRRSPSLSSKHRKGS 664

Query: 937  IALRPTQGDRPQTSSPSRPAQHDP------PQSSFGPTQYNLPSRATSSSHNPGHQSTSR 990
               R T+    +  SP    +H P      PQ+S  P     P R  +SS     QS S 
Sbjct: 665  SPSRSTR----EARSPQPNKRHSPSPRPRAPQTSSSPP----PVRRGASSSPQRRQSPSP 716

Query: 991  TSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESE 1050
            ++ P+   +      +PEP +   A     +   R SS  R +   P P   +P AP S 
Sbjct: 717  STRPIRRVS-----RTPEPKKIKKAASPSPQSVRRVSS-SRSVSGSPEPAAKKPPAPPSP 770

Query: 1051 PPHHEP-PYIPPAVCIGHRDAPRAS-SPPRHT 1080
                 P     PAV +    +P  S SPPR++
Sbjct: 771  VQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNS 802



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 171/803 (21%), Positives = 294/803 (36%), Gaps = 117/803 (14%)

Query: 607  NPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDD-PRASSPNR 665
            +PR  ++ SP+   R +P     +R + R  SP   T+  SP  +  +++  P    P+ 
Sbjct: 171  SPRRRKSRSPSPRRRSSPVRRERKRSHSR--SPRHRTKSRSPSPAPEKKEKTPELPEPSV 228

Query: 666  TIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCA 725
             +++ + + + +  D  +   P    + + P         P  +S  +  ++E  R    
Sbjct: 229  KVKEPSVQEATSTSDILKVPKPEPIPEPKEP--------SPEKNS-KKEKEKEKTRPRSR 279

Query: 726  RRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNR 785
             R   R+ +R+R+     PR     R   R+ SP R       R S  R+ +PR  +P R
Sbjct: 280  SRSKSRSRTRSRSPSHTRPRR--RHRSRSRSYSPRR-------RPSPRRRPSPRRRTPPR 330

Query: 786  ATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLR 845
                 PR       + R+ SP+R  ++ +    +  +   SSS++  +P     KR +  
Sbjct: 331  RMPPPPR-------HRRSRSPVRRRRRSS--ASLSGSSSSSSSSRSRSPPKKPPKRTSSP 381

Query: 846  PTCTQR-DRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRNS-SPHRTN-K 902
            P  T+R   + S   +R  P   S       +     +P +S +    R S SP RT+ K
Sbjct: 382  PRKTRRLSPSASPPRRRHRP---SPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGK 438

Query: 903  DIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDPPQ 962
                     R + S  P+      S+  E     +A   +   R Q    ++ +  D   
Sbjct: 439  VTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGS 498

Query: 963  SSFGPTQYNLPSRATSSSHNPGHQ---STSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIG 1019
            SS   ++   P R+   +   G +   S SR++SP           SP   Q   +    
Sbjct: 499  SS--SSEDERPKRSHVKNGEVGRRRRHSPSRSASP-----------SPRKRQKETSPRGR 545

Query: 1020 HRDAPRASSPPRYLQHDPFPF-FPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPR 1078
             R +P  S PP   +  P P   P  R   + PP    P  PP        +PR  SPP 
Sbjct: 546  RRRSP--SPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPR---RRSPSPRRYSPPI 600

Query: 1079 HTQFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQD 1138
              ++ P P        + +  SP   P +  +P     R     S PP+Q   P      
Sbjct: 601  QRRYSPSP------PPKRRTASPPPPPKRRASPSPPPKRRVSH-SPPPKQRSSP------ 647

Query: 1139 LPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMES 1198
                 T+   PS+ S H               +PS S+   ++P+P+      P      
Sbjct: 648  ----VTKRRSPSLSSKHR-----------KGSSPSRSTREARSPQPNKRHSPSP----RP 688

Query: 1199 LAPSTDSLHGSPVLIPQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPP 1258
             AP T S   SP   P V  G   +P+    P      +  ++ +P P     +   +P 
Sbjct: 689  RAPQTSS---SP---PPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQ 742

Query: 1259 GETRHNLERE-----EYTVLADLPPPRRLAQRQPG-------PQAQCSSGGRTHSPGRAE 1306
               R +  R      E        PP  +  + P        P  +  S   + SP R  
Sbjct: 743  SVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNS 802

Query: 1307 VERLFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPSRQVTMLPAK-QAEL 1365
             +   G++++K         +D+   +     + +  +++ + A +    + PA   A  
Sbjct: 803  DQEGGGKKKKKK--------KDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAAT 854

Query: 1366 TRRSQAEPPHPWSPEKRPEGDRQ 1388
            T  +Q EP     P+K  E + +
Sbjct: 855  TTLAQEEPVAAPEPKKETESEAE 877



 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 155/702 (22%), Positives = 259/702 (36%), Gaps = 106/702 (15%)

Query: 202 DAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRSTLTQASSMTPHSGPRSTTSQASP 261
           +++ +K+E +    R   +  +  R  S +  ER RS      S +P    +S +   +P
Sbjct: 160 ESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRS-----HSRSPRHRTKSRSPSPAP 214

Query: 262 AQRDTA----------------QAASTREI-----------PRASSPHRITQRDTSRASS 294
            +++                  +A ST +I           P+  SP + ++++  +  +
Sbjct: 215 EKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKT 274

Query: 295 TQQEISRASSTQQETSRASS-TQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDN 353
             +  SR+ S  +  SR+ S T+      S ++  +PR   +    P   SP R T    
Sbjct: 275 RPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRP---SPRRRT---- 327

Query: 354 PRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPK 413
                     P    P   P+    R+P  ++    AS    ++   +SR+    +  PK
Sbjct: 328 ----------PPRRMPP-PPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPK 376

Query: 414 ASRTSSPNRATRDNPRTSCAQRDNPRASSPSR---ATRDNPTTSCAQRDNPRASRTS-SP 469
             RTSSP R TR    ++   R   R S P+     TR +PT    Q +  R SR S SP
Sbjct: 377 --RTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQ--QSNRTRKSRVSVSP 432

Query: 470 NRAT-------RDNPRTSCAQRDNPRASSPSRATRDNPTTSCA------QRDNPRASRTS 516
            R +           R S +    PR    S +  D      A      +R   R ++ S
Sbjct: 433 GRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQS 492

Query: 517 SPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPR 576
           S +  +  +      +R + +     R  R +P+ S +     R   TS   R  R    
Sbjct: 493 SSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSP 552

Query: 577 TSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRA 636
               +R +P  + P R  R  PT        PR    S P R    +PR          +
Sbjct: 553 PPTRRRRSPSPAPPPRRRR-TPTPP------PRRRTPSPPPRRRSPSPRRYSPPIQRRYS 605

Query: 637 SSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENP----------RTSCALRDNPR-AS 685
            SP    +  SP     RR  P +  P R +    P          R S +L    R  S
Sbjct: 606 PSPPPKRRTASPPPPPKRRASP-SPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGS 664

Query: 686 SPSR-TIQQENPRTSCAQRDDPRASSPNRTTQ----QENPRTSCARRDNPRASSRNRTIQ 740
           SPSR T +  +P+ +      PR  +P  ++     +    +S  RR +P  S+  R I+
Sbjct: 665 SPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPST--RPIR 722

Query: 741 RDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDN 800
           R + RT   ++    AS   +++++ +   S +    P    P      +P  S +   N
Sbjct: 723 RVS-RTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKP--PAPPSPVQSQSPSTN 779

Query: 801 LRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTKRD 842
              + P++  +   P        P  +S Q+   K    K+D
Sbjct: 780 WSPAVPVKKAKSPTPSPS-----PPRNSDQEGGGKKKKKKKD 816



 Score = 85.9 bits (211), Expect = 4e-16
 Identities = 142/671 (21%), Positives = 236/671 (35%), Gaps = 89/671 (13%)

Query: 85  RGPSPSAGLPEEGPTAAPRSRSRELEAVPYLEGLTTSLCGSCNEDPGSDPTSSPDSATPD 144
           R PSP+    E+ P     S   +  +V   E  +TS      + P  +P   P   +P+
Sbjct: 208 RSPSPAPEKKEKTPELPEPSVKVKEPSVQ--EATSTS---DILKVPKPEPIPEPKEPSPE 262

Query: 145 DTSNSSSVDWDTVERQEEEAPSWDELAVMIP------RRPREGPRADSSQRAPSLLTRSP 198
             S        T  R    + S        P      RR R   R+ S +R PS   R  
Sbjct: 263 KNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPS 322

Query: 199 VGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRSTLTQASSMTPHSGPRSTTSQ 258
                  ++                R R        R RS+ + + S +  S  RS +  
Sbjct: 323 PRRRTPPRRMPPP-----------PRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPP 371

Query: 259 ASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEISRASSTQQETSRASSTQED 318
             P +R ++    TR +  ++SP R   R +  A+   +  +R S T Q+++R   ++  
Sbjct: 372 KKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPK--TRHSPTPQQSNRTRKSRVS 429

Query: 319 TPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENP 378
                ++ + T    + +  +P  +   R  +L    + S +    + +      QR   
Sbjct: 430 VSPGRTSGKVTKHKGTEKRESPSPAPKPRKVEL----SESEEDKGGKMAAADSVQQRRQY 485

Query: 379 RTPCVQQDDPRASSPNRTTQR------ENSRTSCAQRDNPKASRTSSPNRATRDNPRTSC 432
           R    Q      SS +   +R      +N      +R +P  S + SP +  ++      
Sbjct: 486 RRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKET----- 540

Query: 433 AQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSP 492
           + R   R S     TR   + S A     R + T  P R T   P         PR  SP
Sbjct: 541 SPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPP---------PRRRSP 591

Query: 493 SRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTS 552
           S      P         P   RT+SP                      P R A  +P   
Sbjct: 592 SPRRYSPPIQRRYSPSPPPKRRTASP-------------------PPPPKRRASPSPPPK 632

Query: 553 CAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRD----NPTTSCAQRDNP 608
                +P   + SSP    R +P  S   R   + SSP+R+TR+     P    +    P
Sbjct: 633 RRVSHSPPPKQRSSPVTKRR-SPSLSSKHR---KGSSPSRSTREARSPQPNKRHSPSPRP 688

Query: 609 RASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQ 668
           RA +TSS     R    +S  +R +P   SP+    +   RT   ++    AS   ++++
Sbjct: 689 RAPQTSSSPPPVRRGASSSPQRRQSP---SPSTRPIRRVSRTPEPKKIKKAASPSPQSVR 745

Query: 669 QENPRTSCALRDNPRAS---SPSRTIQQENPRTSC--------AQRDDPRASSPNRTTQQ 717
           + +   S +    P A    +P   +Q ++P T+         A+   P  S P  + Q+
Sbjct: 746 RVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQE 805

Query: 718 ENPRTSCARRD 728
              +    ++D
Sbjct: 806 GGGKKKKKKKD 816



 Score = 81.6 bits (200), Expect = 8e-15
 Identities = 141/652 (21%), Positives = 224/652 (34%), Gaps = 97/652 (14%)

Query: 77  PGLRPGPKRGPSPSAGLPEEGPTAAPRSRSRELEAVPYLEGLTTSLCGSCNEDPGSDPTS 136
           P  RP P+R PSP    P       PR R R    V      + SL GS +    S   S
Sbjct: 311 PRRRPSPRRRPSPRRRTPPRRMPPPPRHR-RSRSPVRRRRRSSASLSGSSSSSSSSRSRS 369

Query: 137 SPD-----SATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGPRADSSQRAP 191
            P      +++P   +   S       R+   +P         P + R  P    S R  
Sbjct: 370 PPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSP-----PATPPPKTRHSPTPQQSNRT- 423

Query: 192 SLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRSTLTQASSMTPHSG 251
                         +K   +   GR++G+            + +H+ T  +  S +P   
Sbjct: 424 --------------RKSRVSVSPGRTSGK------------VTKHKGT-EKRESPSPAPK 456

Query: 252 PRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEISRASSTQQETSR 311
           PR      S   +    AA+     R     +  Q  +   SS+  E  R   +  +   
Sbjct: 457 PRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGE 516

Query: 312 ASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQTSFPTC 371
               +  +P  S++     R   T     R  SPS       P T   +  +P       
Sbjct: 517 VGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPS------PPPTRRRRSPSPAP----- 565

Query: 372 TPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSSPNRATRDNPRTS 431
            P+R    TP      PR  +P+   +R   R+   +R +P   R  SP+      P+  
Sbjct: 566 PPRRRRTPTP-----PPRRRTPSPPPRR---RSPSPRRYSPPIQRRYSPS----PPPKRR 613

Query: 432 CAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASS 491
            A    P    P R    +P        +P   + SSP    R +P  S   R   + SS
Sbjct: 614 TASPPPP----PKRRASPSPPPKRRVSHSPPPKQRSSP-VTKRRSPSLSSKHR---KGSS 665

Query: 492 PSRATRD----NPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARD 547
           PSR+TR+     P    +    PRA +TSS     R              +SSP R    
Sbjct: 666 PSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVR-----------RGASSSPQRRQSP 714

Query: 548 NPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDN 607
           +P+T    R   R SRT  P +      + +     + R  S +R+   +P  +  +   
Sbjct: 715 SPST----RPIRRVSRTPEPKKI----KKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPA 766

Query: 608 PRASRTSSPNRATRDNPRTSCAQRDNPRAS-SPNRTTQQDSPRTSCARRDDPRASSPNRT 666
           P  S   S + +T  +P     +  +P  S SP R + Q+       ++ D +     + 
Sbjct: 767 P-PSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKH 825

Query: 667 IQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQE 718
            + +  +   A+     A+     I      T+ AQ +   A  P + T+ E
Sbjct: 826 KKHKKHKKEKAVAAAAAAAVTPAAIAAAT--TTLAQEEPVAAPEPKKETESE 875



 Score = 79.3 bits (194), Expect = 4e-14
 Identities = 165/753 (21%), Positives = 267/753 (35%), Gaps = 140/753 (18%)

Query: 683  RASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRN---RTI 739
            R      + +++  R+   +R   R+ SP R       R+S  RR+  R+ SR+   RT 
Sbjct: 154  RDKEEKESSREKRERSRSPRRRKSRSPSPRR-------RSSPVRRERKRSHSRSPRHRTK 206

Query: 740  QRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRD 799
             R        +   P    P+  +++ +++ + +  D  +   P                
Sbjct: 207  SRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEP---------- 256

Query: 800  NLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFS- 858
              +  SP + ++++  +   ++  PRS S  +   +T      + RP    R R++S+S 
Sbjct: 257  --KEPSPEKNSKKEKEK---EKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSP 311

Query: 859  FQRDNPGTSSSQCCTQKENLRPSSPH----RSTQWNNPRNSSPHRTNKDIPWASFPLRPT 914
             +R +P    S          P  P     RS      R+S+    +     +S    P 
Sbjct: 312  RRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPP 371

Query: 915  QSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPT-QYNLP 973
            +    RTSSP R  +   P AS    P +  RP  S P+ P    PP++   PT Q +  
Sbjct: 372  KKPPKRTSSPPRKTRRLSPSAS---PPRRRHRP--SPPATP----PPKTRHSPTPQQSNR 422

Query: 974  SRATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRD---------AP 1024
            +R +  S +PG     RTS  V          SP P+  P  V +   +         A 
Sbjct: 423  TRKSRVSVSPG-----RTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAAD 477

Query: 1025 RASSPPRYLQHDPFPFFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDP 1084
                  +Y + +         +  SE    +  ++     +G R   R  SP R     P
Sbjct: 478  SVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGE-VGRR---RRHSPSRSASPSP 533

Query: 1085 FPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQDLPRAST 1144
                 +TS    + +SP   P +         R +P  + PPR+   P+      PR  T
Sbjct: 534  RKRQKETSPRGRRRRSPSPPPTRR--------RRSPSPAPPPRRRRTPT----PPPRRRT 581

Query: 1145 ESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLAPSTD 1204
             S  P   S       P+P          +S P ++   PS     PP     +  P   
Sbjct: 582  PSPPPRRRS-------PSP--------RRYSPPIQRRYSPS-----PPPKRRTASPPPPP 621

Query: 1205 SLHGSPVLIPQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPG-SSGGSRGSAPPGETRH 1263
                SP   P+  + H   P+  S P         +    SP  SS   +GS+P   TR 
Sbjct: 622  KRRASPSPPPKRRVSHSPPPKQRSSP---------VTKRRSPSLSSKHRKGSSPSRSTRE 672

Query: 1264 NLEREEYTVLADLPPPRRLAQRQPGPQAQCSSGGRTHSPGRAEVERLFGQERRKSEAAGA 1323
                      A  P P +     P P+A  +S     SP           +RR+S +   
Sbjct: 673  ----------ARSPQPNKRHSPSPRPRAPQTSS----SPPPVRRGASSSPQRRQSPSPST 718

Query: 1324 FQAQDEGRSQQPSQGQSQLLRRQSSPAP--------SRQVTMLPAKQAELTRRSQAEPPH 1375
               +   R+ +P +     +++ +SP+P        SR V+  P   A    +    PP 
Sbjct: 719  RPIRRVSRTPEPKK-----IKKAASPSPQSVRRVSSSRSVSGSPEPAA----KKPPAPPS 769

Query: 1376 P---------WSPEKRPEGDRQLQGSPLPPRTS 1399
            P         WSP    +  +    SP PPR S
Sbjct: 770  PVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNS 802



 Score = 63.2 bits (152), Expect = 3e-09
 Identities = 162/707 (22%), Positives = 244/707 (34%), Gaps = 120/707 (16%)

Query: 946  RPQTSSPSRPAQHDP-PQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPL 1004
            R ++ SP R     P P+    P +     R  S S +P H++ SR+ SP        P 
Sbjct: 166  RERSRSPRRRKSRSPSPRRRSSPVRRE---RKRSHSRSPRHRTKSRSPSPAPEKKEKTP- 221

Query: 1005 TSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESEPPHHEPPYIPPAVC 1064
              PEPS       +  ++A   S   +  + +P P   EP   ++     E     P   
Sbjct: 222  ELPEPSVKVKEPSV--QEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRP--- 276

Query: 1065 IGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRASS 1124
               R   R+ S  R     P    P      H+ +S  + P + P+P     R +PR  +
Sbjct: 277  ---RSRSRSKSRSRTRSRSPSHTRPRR---RHRSRSRSYSPRRRPSP---RRRPSPRRRT 327

Query: 1125 PPRQAPEPSLLFQDLP-----RASTESLVPSMDSLHEC-----PHIP-----TPVCIGHR 1169
            PPR+ P P    +        R S+ SL  S  S         P  P     +P     R
Sbjct: 328  PPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRR 387

Query: 1170 DAPSFSSPPRQAPEPSLFFQDPPGTSMESLAPSTDSLHGSPVLI-PQVCIG----HRDAP 1224
             +PS +SPPR+   PS     PP T        ++    S V + P    G    H+   
Sbjct: 388  LSPS-ASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTE 446

Query: 1225 RASSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVLADLPPPRRLAQ 1284
            +  SP   P      L  S S    GG   +A   + R    R+     +D         
Sbjct: 447  KRESPSPAPKPRKVEL--SESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSED 504

Query: 1285 RQPGPQAQCSSGG----RTHSPGRAEVERLFGQERRKSEAAGAFQAQDEG---RSQQPSQ 1337
             +P  ++   +G     R HSP R+       +++  S      ++       R + PS 
Sbjct: 505  ERP-KRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSP 563

Query: 1338 GQSQLLRRQSSPAPSRQVTMLPAKQAELTRRSQAEPPHPWSPEKR---PEGDRQLQGSPL 1394
                  RR  +P P               RR+ + PP   SP  R   P   R+   SP 
Sbjct: 564  APPPRRRRTPTPPP--------------RRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPP 609

Query: 1395 PPRTSARTPERELRTQRPLESGQAGPRQPLGVWQSQEEPPGSQGPHRHLERSWSSQEGGL 1454
            P R +A  P        P    +A P  P     S   PP  +       RS        
Sbjct: 610  PKRRTASPP--------PPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRS-------- 653

Query: 1455 GPGGWWGCGEPSLGAAKAPEGAWGGTSREYKESWGQPEAWEEKPTHELPRELGKRSPLT- 1513
                      PSL ++K  +G+    SR  +E+          P+   PR    R+P T 
Sbjct: 654  ----------PSL-SSKHRKGS--SPSRSTREARSPQPNKRHSPS---PR---PRAPQTS 694

Query: 1514 -SPPENWGGPAESSQSWHSGTPTAVGWGAEGACPYPRGSER---------RPELDWRDLL 1563
             SPP    G + S Q   S +P+          P P+  ++         R     R + 
Sbjct: 695  SSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVS 754

Query: 1564 GLLR-------APGEGVWARVPSLDWEGLLELLQARLPRKDPAGHRD 1603
            G          AP   V ++ PS +W   + + +A+ P   P+  R+
Sbjct: 755  GSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRN 801



 Score = 40.8 bits (94), Expect = 0.016
 Identities = 67/314 (21%), Positives = 107/314 (34%), Gaps = 41/314 (13%)

Query: 65  SASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTAAPRSRSRELEAVPYLEGLTTSLCG 124
           SAS S  +   +   R   +R PSP        P+ AP  R R     P      +    
Sbjct: 528 SASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPR 587

Query: 125 SCNEDPG--SDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGP 182
             +  P   S P     S +P     ++S       R     P    ++   P + R  P
Sbjct: 588 RRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSP 647

Query: 183 RADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRSTLTQ 242
              + +R+PSL ++   G   +   +E                   S    +RH  +   
Sbjct: 648 --VTKRRSPSLSSKHRKGSSPSRSTRE-----------------ARSPQPNKRHSPSPRP 688

Query: 243 ASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRAS---SPHRITQRDTSRASSTQQEI 299
            +  T  S P      +S  QR  + + STR I R S    P +I +     AS + Q +
Sbjct: 689 RAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKK----AASPSPQSV 744

Query: 300 SRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWN-----------TPRASSPSRS 348
            R SS++  +       +  P   S  +   ++ ST W+           TP  S P  S
Sbjct: 745 RRVSSSRSVSGSPEPAAKKPPAPPSPVQS--QSPSTNWSPAVPVKKAKSPTPSPSPPRNS 802

Query: 349 TQLDNPRTSSTQQD 362
            Q    +    ++D
Sbjct: 803 DQEGGGKKKKKKKD 816


>gi|239753963 PREDICTED: similar to apopolysialoglycoprotein [Homo
           sapiens]
          Length = 538

 Score = 98.2 bits (243), Expect = 8e-20
 Identities = 116/531 (21%), Positives = 217/531 (40%), Gaps = 49/531 (9%)

Query: 252 PRSTTSQASPAQR--DTAQAASTREIPRASSPHRITQRDTSRASSTQQEISRASSTQQET 309
           P  T S+A+  +   DT   A+ R  P  ++   + +R  +   S   +    + T  E 
Sbjct: 23  PADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPADTMSEAAQRRHPADTMSEA 82

Query: 310 SRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQTSFP 369
            +     +    A+  +      S        A + S + Q  +P  + T  +  Q   P
Sbjct: 83  VQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHP--ADTMSEAAQRRHP 140

Query: 370 TCTP----QRENPR---TPCVQQDDPRASSPNRTTQREN---SRTSCAQRDNPKASRTSS 419
             T     QR +P    +  VQ+ DP A + +   QR +   + +  AQR +P  + + +
Sbjct: 141 ADTMSEAVQRRHPADTMSEAVQRRDP-ADTMSEAVQRRHPADTMSEAAQRRHPADTMSEA 199

Query: 420 PNRATRDNPRTSCAQRDNPRASSPSRATRDNPT---TSCAQRDNPRASRTSSPNRATRDN 476
             R    +  +  AQR +P  +    A R +P    +  AQR +P  + + +  R    +
Sbjct: 200 AQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPAD 259

Query: 477 PRTSCAQRDNPRASSPSRATRDNPT---TSCAQRDNPRASRTSSPNRATRDNPRTSCAQR 533
             +  AQR +P  +    A R +P    +  AQR +P  + + +  R    +  +  AQR
Sbjct: 260 TISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQR 319

Query: 534 DNPRASSPNRAARDNPT---TSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSP 590
            +P  +    A R +P    +   QR +P  + + +  R    +  +  AQR +P  +  
Sbjct: 320 RDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMS 379

Query: 591 NRATRDNPT---TSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDS 647
             A R +P    +  AQR +P  + + +  R    +  +  AQR +P  +      ++D 
Sbjct: 380 EAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRRDP 439

Query: 648 PRT--SCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQE---NPRTSCAQ 702
             T    A+R DP A + +   Q+ +P           A + S  +Q+    +P +  AQ
Sbjct: 440 ADTMSEAAQRRDP-ADTMSEAAQRRHP-----------ADTTSEAVQRRHPADPMSEAAQ 487

Query: 703 RDDPRASSPNRTTQQENPR---TSCARRDNPRASSRNRTIQRDNPRTSCAQ 750
           R D  A + +   Q+ +P    +  A+R +P A + +   QR +P  + ++
Sbjct: 488 RRD-LADTMSEAAQRRDPEDTMSEAAQRRDP-ADAMSEAAQRRDPEDTMSE 536



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 65/336 (19%), Positives = 129/336 (38%), Gaps = 15/336 (4%)

Query: 235 RHRSTLTQASSMTPHSGPRSTTSQASPAQ--RDTAQAASTREIPRASSPHRITQRDTSRA 292
           + R      S       P  T S+A+  +   DT   A+ R  P  +      +RD +  
Sbjct: 201 QRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADT 260

Query: 293 SSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLD 352
            S   +    + T  E ++     +    A+  ++     S        A + S + Q  
Sbjct: 261 ISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRR 320

Query: 353 NPR---TSSTQQDNPQTSFPTCTPQRENPRT--PCVQQDDPRASSPNRTTQRENSRT--S 405
           +P    + + Q+ +P  +      +R    T    VQ+  P  +      +R+ + T   
Sbjct: 321 DPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMSE 380

Query: 406 CAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPT---TSCAQRDNPR 462
            AQR +P  + + +  R    +  +  AQR +P  +    A R +P    +  AQR +P 
Sbjct: 381 AAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRRDPA 440

Query: 463 ASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPT---TSCAQRDNPRASRTSSPN 519
            + + +  R    +  +  AQR +P  ++     R +P    +  AQR +   + + +  
Sbjct: 441 DTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQRRDLADTMSEAAQ 500

Query: 520 RATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQ 555
           R   ++  +  AQR +P  +    A R +P  + ++
Sbjct: 501 RRDPEDTMSEAAQRRDPADAMSEAAQRRDPEDTMSE 536


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 97.1 bits (240), Expect = 2e-19
 Identities = 246/1109 (22%), Positives = 387/1109 (34%), Gaps = 167/1109 (15%)

Query: 238  STLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASS--PHRITQRDTSRASS- 294
            +T+   SS  P   P S  + ASP Q     A  T   P ASS  P R T   T +A+S 
Sbjct: 1228 TTIGLLSSTGP--SPSSNHTPASPTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSG 1285

Query: 295  -----TQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPS--- 346
                 T +  +   +  Q T+RA+++   +P  +ST + T R + T   TP  S  S   
Sbjct: 1286 LPPTATLRSTATKPTVTQATTRATASTA-SPATTSTAQSTTRTTMT-LPTPATSGTSPTL 1343

Query: 347  -RSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTS 405
             +ST  + P T++TQ   P+ +  + T     P TP  Q   P   +   TTQ   +RT+
Sbjct: 1344 PKSTNQELPGTTATQTTGPRPTPASTT----GPTTP--QPGQPTRPTATETTQ---TRTT 1394

Query: 406  CAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASR 465
                       T SP  A    P T      +  A++ +  T  +P T+      P ++ 
Sbjct: 1395 TEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATT-TYPTPSHPETTLPTHVPPFSTS 1453

Query: 466  TSSPNRATRDNP-----RTSCAQRDNPRASSPSRAT-RDNPTTSCAQRDNPRASRTSSPN 519
              +P+  T   P      TS +    P  + P   T +   +T  A    P  S TS  +
Sbjct: 1454 LVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAH 1513

Query: 520  RATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSP----NRATRDNP 575
             +   N   +           P       PT++     NP ++RT +P    N AT   P
Sbjct: 1514 SSFSTNKTPTSLHSHTSSTHHP----EVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRP 1569

Query: 576  RTSCAQRDNPRASSP----------------NRATRDNPTTSCAQRDNPRASRTSSPNRA 619
                     P  SSP                   T  +P T+      P ++   +P+  
Sbjct: 1570 PPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTH 1629

Query: 620  TRDNP-----RTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQEN-PR 673
            T   P      TS +    P  + P  TT + +  T  A       S  ++ +   N  +
Sbjct: 1630 TVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAK 1689

Query: 674  TSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRAS 733
            TS +L      S  S T   E   TS          +PN T+    P T      +   S
Sbjct: 1690 TSTSLH-----SHTSSTHHAEATSTSTTN------ITPNPTSTGTPPMTVTTSGTSQSRS 1738

Query: 734  SRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRT 793
            S +      +  +  +   +P  +S + T    N  ++ TR     T+S   +    P T
Sbjct: 1739 SFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFT 1798

Query: 794  SCAQRDN---LRASSPIRATQ---------QDNPRTCIQQNIPRSSSTQQDNPKTSCTKR 841
            + +       + ++ P+ AT            +P T +  ++P S ST    P T     
Sbjct: 1799 THSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVP-SFSTSLVTPSTHTV-- 1855

Query: 842  DNLRPTCTQRDRTQSFSFQRDN--PGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHR 899
              + PT TQ   + S         P  ++ +         P +P  S    +P + S  +
Sbjct: 1856 --IIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAK 1913

Query: 900  TNKDIPWAS--------FPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQTSS 951
            T+  +P+ +         P   T      TS+ +R+  +    AS +  PT    P T+ 
Sbjct: 1914 TSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPT----PFTT- 1968

Query: 952  PSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTS--RTSSPVYPAAYGAPLTSPEP 1009
                  H PP  S  P     P  ATS      + + S  +T+ P +   +   L +P  
Sbjct: 1969 ------HSPPTGS-SPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPST 2021

Query: 1010 SQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESE-PPHHEPPYIPPAVCIGHR 1068
                  +   H     ++S    +   P    P P   ++    H  PP           
Sbjct: 2022 H---TVIITTHTQMATSAS----IHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQT 2074

Query: 1069 DAPRASSPPRHTQFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRASSPPRQ 1128
             +  +++    +      +LP  S +      P   P+    P          A++P   
Sbjct: 2075 HSSFSTATASSSFISSSSWLPQNSSSR-----PPSSPITTQLP------HLSSATTPVST 2123

Query: 1129 APEPSLLFQDLPRA--STESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQAPEPSL 1186
              + S  F   P A  +  S VPS    H  P   +P       +   SS    AP  S 
Sbjct: 2124 TNQLSSSFSPSPSAPSTVSSYVPSS---HSSPQTSSP-------SVGTSSSFVSAPVHST 2173

Query: 1187 FFQDPPGTSMESLAPSTDSLHGSPVLIPQVCIGHRDAPRASSPPR-------HPPSDLAF 1239
                   +S+ S  P+T S+  SP L P        +P AS+  R         P  L+ 
Sbjct: 2174 TLSSGSHSSL-STHPTTASVSASP-LFP-------SSPAASTTIRATLPHTISSPFTLSA 2224

Query: 1240 LAP------SPSPGSSGGSRGSAPPGETR 1262
            L P      SP+P S   S   A P   R
Sbjct: 2225 LLPISTVTVSPTPSSHLASSTIAFPSTPR 2253



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 124/558 (22%), Positives = 195/558 (34%), Gaps = 98/558 (17%)

Query: 243  ASSMTPHSGPRST---------TSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRAS 293
            A+S + HS P  T         T     A   T   + T + P + S  + +       S
Sbjct: 1864 ATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTS 1923

Query: 294  STQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASS--TQWNTPRASSPSRSTQL 351
            ST       +ST   T + +ST   TP A +T   + R  +  T  + P  SSP  ST  
Sbjct: 1924 STHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSST-- 1981

Query: 352  DNPRTSSTQQ--------DNPQTSFPTCTPQREN----PRTPCVQ-------------QD 386
              P T+++ Q         +PQT+ PT  P        P T  V                
Sbjct: 1982 -GPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHS 2040

Query: 387  DPRASSPNRTTQRENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASS--PS 444
             P  + P  TT +    T  A    P  + T+S    T  +  T+ A      +SS  P 
Sbjct: 2041 TPTGTVPPPTTLKATGSTHTA----PPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQ 2096

Query: 445  RATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSC 504
             ++   P++            T  P+ ++   P ++  Q  +  + SPS  +    T S 
Sbjct: 2097 NSSSRPPSSPIT---------TQLPHLSSATTPVSTTNQLSSSFSPSPSAPS----TVSS 2143

Query: 505  AQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRD-----NP 559
                +  + +TSSP+  T  +   S        +S  + +   +PTT+          +P
Sbjct: 2144 YVPSSHSSPQTSSPSVGTSSS-FVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSP 2202

Query: 560  RASRT---------SSPNRATRDNPRTSCAQRDNPRA--SSPNRATRDNPTTSCAQRDNP 608
             AS T         SSP   +   P ++      P +  +S   A    P T+ +    P
Sbjct: 2203 AASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAP 2262

Query: 609  RASRTSSPNRATRDNPRT--------SCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRA 660
              S  S+ +R+T    R         +      P +   N TT+   P  S   R    +
Sbjct: 2263 AFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSS 2322

Query: 661  SSPNRTIQQENPRTSCALRDNPRASSPS----RTIQQENPRTSCAQRDDPR--------A 708
             + + +     P +S      P  +SP     R  Q+E     C               A
Sbjct: 2323 LTAHGSTPASAPVSSLG---TPTPTSPGVCSVREQQEEITFKGCMANVTVTRCEGACISA 2379

Query: 709  SSPNRTTQQENPRTSCAR 726
            +S N  TQQ + R SC R
Sbjct: 2380 ASFNIITQQVDARCSCCR 2397



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 130/608 (21%), Positives = 204/608 (33%), Gaps = 78/608 (12%)

Query: 229  SGLSLERHRSTLTQASSMTPHSGPRST-TSQASPAQRDTAQAASTREIPRASSPHRITQR 287
            S L+  +  ++L   +S T H+   ST T+  +P    T     T      S     ++ 
Sbjct: 1683 SSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQ----SRS 1738

Query: 288  DTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRA----- 342
              S A ++    S  SST      ++ST   TP  +ST   TP A +T   + R      
Sbjct: 1739 SFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFT 1798

Query: 343  --SSPSRSTQLDN--PRTSSTQQ--------DNPQTSFPT---------CTPQRENPRTP 381
              S P+ +T + +  P T+++ Q         +P T+ PT          TP       P
Sbjct: 1799 THSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIP 1858

Query: 382  CVQQ--------DDPRASSPNRTTQRENSRTSCAQRDNPKASRTS-SPNRATRDNPRTS- 431
               Q          P  + P  TT +    T  A    P  S TS SP+  +     TS 
Sbjct: 1859 THTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSL 1918

Query: 432  ---CAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSS-----PNRATRDNPRTSCA- 482
                +   +P   +P+  T   P  +      P A  TS+     P   T  +P T  + 
Sbjct: 1919 PYHTSSTHHPEV-TPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSP 1977

Query: 483  -QRDNPRASSPSRATRDNPTTSCAQRDNPR----------ASRTSSPNRATRDNPRTSCA 531
                 P  ++  + T   PT S  Q   P              T +    T     TS +
Sbjct: 1978 FSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSAS 2037

Query: 532  QRDNPRASSPNRAARDNPTTSCAQRDN---PRASRTSSPNRATRDNPRTSCAQRDNPRAS 588
                P  + P       PTT  A       P  + T+S    T  +  T+ A      +S
Sbjct: 2038 IHSTPTGTVP------PPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSS 2091

Query: 589  S--PNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQD 646
            S  P  ++   P +S      P  S  ++P   T     +       P   S    +   
Sbjct: 2092 SWLPQNSS-SRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHS 2150

Query: 647  SPRTS--CARRDDPRASSP-NRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQR 703
            SP+TS           S+P + T       +S +      + S S         ++  + 
Sbjct: 2151 SPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRA 2210

Query: 704  DDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQ-RDNPRTSCAQRDNPRASSPNRT 762
              P   S   T     P ++      P +   + TI     PRT+ +    P  SS + T
Sbjct: 2211 TLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTT 2270

Query: 763  IQQENLRT 770
             +  +L T
Sbjct: 2271 SRSTSLTT 2278



 Score = 36.2 bits (82), Expect = 0.39
 Identities = 85/335 (25%), Positives = 120/335 (35%), Gaps = 50/335 (14%)

Query: 941  PTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAY 1000
            PT    P T S  RP Q  P   +   T   L S +T  S +  H   S T +P+ PA  
Sbjct: 1205 PTTPQLPTTGS--RPTQVWPMTGT--STTIGLLS-STGPSPSSNHTPASPTQTPLLPATL 1259

Query: 1001 GA---PLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESEPPHHEPP 1057
             +     +S EP +P  AV       P+A+S          P     R+  ++P   +  
Sbjct: 1260 TSSKPTASSGEPPRPTTAV------TPQATS--------GLPPTATLRSTATKPTVTQAT 1305

Query: 1058 YIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQSPQHEPLQLP---APVCI 1114
                A          A S  R T   P P    TS        P+    +LP   A    
Sbjct: 1306 TRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPT-----LPKSTNQELPGTTATQTT 1360

Query: 1115 GYRDAPRASS-----PPRQAPEPSLLFQDLPRASTESLVP-SMDSLHECPHIPTPV-CIG 1167
            G R  P +++      P Q   P+       R +TE   P +  + H  P   +PV   G
Sbjct: 1361 GPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTG 1420

Query: 1168 HRDAPSFSS----PPRQAPEPSLFFQDPPGTSMESLAPSTDSLHGSPVLIPQVCIGHRDA 1223
               A SF +    P    PE +L    PP  S   + PST ++             +  A
Sbjct: 1421 PVTATSFHATTTYPTPSHPETTLPTHVPP-FSTSLVTPSTHTVITPTHAQMATSASNHSA 1479

Query: 1224 PRASSPPRHPPSDL-----AFLAPSPSPGSSGGSR 1253
            P  + P   PP+ L        AP  +P +SG S+
Sbjct: 1480 PTGTIP---PPTTLKATGSTHTAPPITPTTSGTSQ 1511



 Score = 35.0 bits (79), Expect = 0.87
 Identities = 51/272 (18%), Positives = 95/272 (34%), Gaps = 16/272 (5%)

Query: 131  GSDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGPRADSSQRA 190
            G+  T S  S     +S  SS  W  + +     P    +   +P          ++ + 
Sbjct: 2070 GTSQTHSSFSTATASSSFISSSSW--LPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQL 2127

Query: 191  PSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRSTLTQASSMTPHS 250
             S  + SP            +    +++          S +S   H +TL+  S  +  +
Sbjct: 2128 SSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGT--SSSFVSAPVHSTTLSSGSHSSLST 2185

Query: 251  GPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEISRASSTQQETS 310
             P + +  ASP    +  A++T    RA+ PH I+   T  A      ++ + +     +
Sbjct: 2186 HPTTASVSASPLFPSSPAASTTI---RATLPHTISSPFTLSALLPISTVTVSPTPSSHLA 2242

Query: 311  RASSTQEDTPR---------ASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQ 361
             ++     TPR         A S+Q  T R++S     P +   S ++ +    TS    
Sbjct: 2243 SSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTN 2302

Query: 362  DNPQTSFPTCTPQRENPRTPCVQQDDPRASSP 393
               +   PT +P      +         AS+P
Sbjct: 2303 LTTRHPGPTLSPTTRFLTSSLTAHGSTPASAP 2334


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 95.1 bits (235), Expect = 7e-19
 Identities = 160/849 (18%), Positives = 297/849 (34%), Gaps = 108/849 (12%)

Query: 228  ESGLSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQR 287
            ES    E H  +  Q SS +  S   S+T +   + +++A   + RE+ +        + 
Sbjct: 109  ESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSA---ANRELQKKLKVKDNKKN 165

Query: 288  DTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDT-PRASSTQWNTPRASSP- 345
             T +  + +  +   + +  +      T  DT      +  T P+ ++ +   PR S P 
Sbjct: 166  RTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPP 225

Query: 346  ----SRSTQLD-NPRTSSTQQDNPQTSFPTCTPQRENP----RTPCVQQDDPRASSPN-- 394
                S+ T L  N  T+   ++   T+  T T  +E       T  +++   +  +P   
Sbjct: 226  NSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 285

Query: 395  ---RTTQRENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNP 451
               + T +  + T       PK    ++P       P+           S+P+      P
Sbjct: 286  VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPK---EPTPTTIKSAPTTPKEPAP 342

Query: 452  TTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPR 511
            TT+   +  P   +  +P       P T       P+  +P+      PTT+ +    P+
Sbjct: 343  TTT---KSAPTTPKEPAPTTTKEPAPTT-------PKEPAPTTTKEPAPTTTKSAPTTPK 392

Query: 512  ASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRAT 571
                ++P +     P+        P+  +P       PTT       P+    ++P +  
Sbjct: 393  EPAPTTPKKPAPTTPKEPAP--TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 450

Query: 572  RDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQR 631
               P+        P+  +P      +PTT    ++    +  S+P       P T+ +  
Sbjct: 451  PTTPKEPAP--TTPKEPAPTTTKEPSPTT---PKEPAPTTTKSAPTTTKEPAPTTTKSAP 505

Query: 632  DNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTI 691
              P+  SP  TT++ +P T       P+  +P  T ++  P T            P+ T 
Sbjct: 506  TTPKEPSPT-TTKEPAPTT-------PKEPAPT-TPKKPAPTT---------PKEPAPTT 547

Query: 692  QQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQR 751
             +E   T+  +        P  TT +E   T+  ++  P    +      + P  +  + 
Sbjct: 548  PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT-PKKLTPTTPEKLAPTTPEKPAPTTPEE 606

Query: 752  DNPRA-SSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRAT 810
              P     P  T  +E   T+      P+ ++PN      P T            P   T
Sbjct: 607  LAPTTPEEPTPTTPEEPAPTT------PKAAAPNTPKEPAPTT---------PKEPAPTT 651

Query: 811  QQDNPRTCIQQNIPRSSSTQQDNPK-TSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSS 869
             ++   T  ++  P +       PK T+ T      PT  ++   +  +     P T+  
Sbjct: 652  PKEPAPTTPKETAPTT-------PKGTAPTTLKEPAPTTPKKPAPKELA-----PTTTKE 699

Query: 870  QCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQ 929
               T  +   P++P + T    P+  +P    +  P       PT    P  ++P +   
Sbjct: 700  PTSTTCDKPAPTTP-KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 758

Query: 930  SEV-PWASIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQST 988
             E+ P  +     T  D+P  ++P   A   P + +  PT    P+  T  +  P   +T
Sbjct: 759  KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA--PTTPKKPAPTTPETPPP---TT 813

Query: 989  SRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPE 1048
            S  S+P           SP+ S P  +          A   P+ L++ P     EP  P 
Sbjct: 814  SEVSTPTTTKEPTTIHKSPDESTPELS----------AEPTPKALENSP----KEPGVPT 859

Query: 1049 SEPPHHEPP 1057
            ++ P    P
Sbjct: 860  TKTPAATKP 868



 Score = 79.3 bits (194), Expect = 4e-14
 Identities = 135/722 (18%), Positives = 249/722 (34%), Gaps = 98/722 (13%)

Query: 58   PAPEDPLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEE---------GPTA---APRSR 105
            PAP    SA T+  +       +P P     P+   P+E          PT    AP + 
Sbjct: 379  PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 438

Query: 106  SRELEAVPYLEGLTT--SLCGSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEE 163
                   P     TT      +  ++P    T  P   TP + + +++    T  +  E 
Sbjct: 439  KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK--EP 496

Query: 164  APSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWA 223
            AP+  + A   P  P+E     + + AP+    +P        KK               
Sbjct: 497  APTTTKSA---PTTPKEPSPTTTKEPAPT----TPKEPAPTTPKKPAP------------ 537

Query: 224  RLRGESGLSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHR 283
                          +T  + +  TP     +TT + +P       A +T +    ++P +
Sbjct: 538  --------------TTPKEPAPTTPKEPAPTTTKKPAPT-TPKEPAPTTPKETAPTTPKK 582

Query: 284  ITQRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRA-SSTQEDTPRASSTQWNTPRA 342
            +T     + + T  E  + + T  E    ++ +E TP         TP+A++   NTP+ 
Sbjct: 583  LTPTTPEKLAPTTPE--KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP--NTPKE 638

Query: 343  SSPS-----RSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTT 397
             +P+       T    P  ++ ++  P T   T     + P     ++  P+  +P  TT
Sbjct: 639  PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP--TT 696

Query: 398  QRENSRTSCAQ--RDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSC 455
             +E + T+C +     PK +  ++P       P+        P+ ++P+      PTT  
Sbjct: 697  TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP--TTPKGTAPTTLKEPAPTTPK 754

Query: 456  AQRDNPRA-SRTSSPNRATRDNPRTSCAQRDNPRA-SSPSRATRDNPTTSCAQRDNPRAS 513
                   A + T  P   T D P  +  +   P     P+  T   P  +  +   P  S
Sbjct: 755  KPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS 814

Query: 514  RTSSPNRATRDNPRTSCAQRDNPRASS-PNRAARDN-------PTTSCAQRDNPRASRTS 565
              S+P                 P  S+ P   A +N       PTT       P  + T+
Sbjct: 815  EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA 874

Query: 566  SPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPN-------- 617
                  RD   T       P+ +     T +  T S       + + T++ +        
Sbjct: 875  KDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT 934

Query: 618  -RATRDNPRTSCAQRDNPRASSPNRTTQQDSP--RTSCARRDDPR----ASSPNRTIQQE 670
             + T   P+ +  ++        N+  +   P  R + ++   P+      +P +    +
Sbjct: 935  LKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTK 994

Query: 671  NPRTSCALRDNPRASSPSR---TIQQENPRTSCAQRDDPRASSPNRTTQQE----NPRTS 723
             P+T   +R      +P +   T+ + NP +  A+      + PN+T   +    NP++ 
Sbjct: 995  KPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSE 1054

Query: 724  CA 725
             A
Sbjct: 1055 DA 1056



 Score = 78.6 bits (192), Expect = 7e-14
 Identities = 176/900 (19%), Positives = 290/900 (32%), Gaps = 97/900 (10%)

Query: 530  CAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASS 589
            CA+  NP  +SP  + +  P +  +Q       R+  P    +        +     + S
Sbjct: 63   CAEVHNP--TSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVS 120

Query: 590  PNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPR 649
             N+ +  + ++S +     +    SS N A     +     +DN +    NRT ++ +P+
Sbjct: 121  ENQESSSSSSSSSSSSTIRKIK--SSKNSAANRELQKKLKVKDNKK----NRTKKKPTPK 174

Query: 650  TSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRAS 709
                  D+  +   N   +   P TS    +    S    T +  NPR S     D    
Sbjct: 175  PPVV--DEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKE 232

Query: 710  SPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLR 769
            +     ++    T      N + S+  +        T   ++ + +  +P   +  +   
Sbjct: 233  TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP 292

Query: 770  TSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQ--NIPRSS 827
             + T    P  ++P   T   P+   +         P   T +  P T  +      +S+
Sbjct: 293  KAETTTKGPALTTPKEPTPTTPKEPASTTPK----EPTPTTIKSAPTTPKEPAPTTTKSA 348

Query: 828  STQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRST 887
             T    P  + TK     P  T        + +   P T+ S   T KE   P++P +  
Sbjct: 349  PTTPKEPAPTTTKE----PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA-PTTPKKPA 403

Query: 888  QWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRP 947
                P+  +P  T    P  + P  P     P T  P+ +   E         PT   +P
Sbjct: 404  P-TTPKEPAP--TTPKEPTPTTPKEPA----PTTKEPAPTTPKEPA-------PTAPKKP 449

Query: 948  QTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNP--GHQSTSRTSSPVYPAAYGAPLT 1005
              ++P  PA   P + +  PT    PS  T     P     + + T  P       AP T
Sbjct: 450  APTTPKEPAPTTPKEPA--PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 507

Query: 1006 SPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESEPPHHEPPYIP--PAV 1063
              EPS                  P      +P P  P+  AP +  P    P  P  PA 
Sbjct: 508  PKEPS------------PTTTKEPAPTTPKEPAPTTPKKPAPTT--PKEPAPTTPKEPAP 553

Query: 1064 CIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRAS 1123
                + AP        T  +P P    T+  E    +P+      P  +     + P  +
Sbjct: 554  TTTKKPAPT-------TPKEPAP----TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT 602

Query: 1124 SPPRQAP----EPSLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPR 1179
            +P   AP    EP+    + P  +T             P  P          P+ ++P  
Sbjct: 603  TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKE 662

Query: 1180 QAPEPSLFFQDPPGTSMESL---APSTDSLHGSPVLIPQVCIGHRDAPRASSPPRHPPSD 1236
             AP        P GT+  +L   AP+T        L P               P  P   
Sbjct: 663  TAP------TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 716

Query: 1237 LAFLAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVLADLPPPRRLA-QRQPGPQAQCSS 1295
                   P+P +      + P G     L +E        P P+ LA     GP +  S 
Sbjct: 717  APTTPKEPAPTTPKEPAPTTPKGTAPTTL-KEPAPTTPKKPAPKELAPTTTKGPTSTTSD 775

Query: 1296 GGRTHSPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPSRQV 1355
                 +P              K  A    +       + P    S++    S+P  +++ 
Sbjct: 776  KPAPTTPKET------APTTPKEPAPTTPKKPAPTTPETPPPTTSEV----STPTTTKEP 825

Query: 1356 TMLPAKQAELTRRSQAEPPHPW---SPEKRPEGDRQLQGSPLPPRTSA---RTPERELRT 1409
            T +     E T    AEP       SP++      +   +  P  T+    +T ER+LRT
Sbjct: 826  TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 885



 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 102/552 (18%), Positives = 190/552 (34%), Gaps = 48/552 (8%)

Query: 42   SPSGAEVPYCDLPRCPPAPEDPLS-ASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTA 100
            SP+  + P    P+  PAP  P   A T+  +        P P     P+   P+E    
Sbjct: 512  SPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 570

Query: 101  APRSRSRELEAVPYLEGLTTSLCGSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQ 160
             P+      E  P        L  +  E         P   TP++ + ++  +  T    
Sbjct: 571  TPK------ETAPTTP---KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE-PTPTTP 620

Query: 161  EEEAPSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQ 220
            EE AP+  + A   P  P+E       + AP+   + P              G   +  +
Sbjct: 621  EEPAPTTPKAAA--PNTPKEPAPTTPKEPAPTT-PKEPAPTTPKETAPTTPKGTAPTTLK 677

Query: 221  HWARLRGESGLSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASS 280
              A    +     E   +T  + +S T    P  TT + +        A +T + P  ++
Sbjct: 678  EPAPTTPKKPAPKELAPTTTKEPTSTTCDK-PAPTTPKGTAPTTPKEPAPTTPKEPAPTT 736

Query: 281  PHRITQRDTSR-ASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNT 339
            P           A +T ++ +        T   +ST  D P  ++ +E  P        T
Sbjct: 737  PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP-------TT 789

Query: 340  PRASSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQR 399
            P+  +P+   +       +T +  P T+    TP     + P      P  S+P  + + 
Sbjct: 790  PKEPAPTTPKK----PAPTTPETPPPTTSEVSTP--TTTKEPTTIHKSPDESTPELSAE- 842

Query: 400  ENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNP-TTSCAQR 458
                T  A  ++PK     +        P  +   +D     +  R  R  P TT+ A +
Sbjct: 843  ---PTPKALENSPKEPGVPTTKTPAATKPEMTTTAKD----KTTERDLRTTPETTTAAPK 895

Query: 459  DNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSS- 517
                 + T+     ++    T+       + ++P + T    TT   +    + + T++ 
Sbjct: 896  MTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE 955

Query: 518  ----PNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASR---TSSPNRA 570
                P    +   R + ++   P+   P +A +  PT++   +  PR  +   T +P + 
Sbjct: 956  IMNKPEETAKPKDRATNSKATTPKPQKPTKAPK-KPTSTKKPKTMPRVRKPKTTPTPRKM 1014

Query: 571  TRDNPRTSCAQR 582
            T   P  +   R
Sbjct: 1015 TSTMPELNPTSR 1026



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 182/988 (18%), Positives = 308/988 (31%), Gaps = 148/988 (14%)

Query: 1129 APEPSLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFF 1188
            AP   +L +  P+A T +  P++ +    P  PTP        P+ ++P    P      
Sbjct: 281  APTSKVLAKPTPKAETTTKGPALTT----PKEPTPTT---PKEPASTTPKEPTPTT---I 330

Query: 1189 QDPPGTSMESLAPSTDSLHGSPVLIPQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGS 1248
            +  P T  E    +T S   +P            AP  +  P   P+     AP+ +   
Sbjct: 331  KSAPTTPKEPAPTTTKSAPTTP---------KEPAPTTTKEPA--PTTPKEPAPTTTKEP 379

Query: 1249 SGGSRGSAP--PGETRHNLEREEYTVLADLPPPRRLAQRQPGPQAQCSSGGRTHSPGRAE 1306
            +  +  SAP  P E      ++        P P     ++P P         T  P    
Sbjct: 380  APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT--TPKEPTPTTPKEPAPTTKEPAPTT 437

Query: 1307 VERLFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPSRQVTMLPAKQAELT 1366
             +       +K     A     E     P +  +    ++ SP   ++      K A  T
Sbjct: 438  PKEPAPTAPKKP----APTTPKEPAPTTPKE-PAPTTTKEPSPTTPKEPAPTTTKSAPTT 492

Query: 1367 RRSQAEPPHPWSPE--KRPEGDRQLQGSPLPPRTSARTPERELRTQRPLESGQAGPRQPL 1424
             +  A      +P   K P      + +P  P+  A T  ++     P E     P++P 
Sbjct: 493  TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 552

Query: 1425 GVWQSQEEP--PGSQGPHRHLERSWSSQEGGLGPGGWWGCGEPSLGAAKAPEGAWGGTSR 1482
                 +  P  P    P    E + ++ +  L P        P   A   PE     T  
Sbjct: 553  PTTTKKPAPTTPKEPAPTTPKETAPTTPKK-LTPT------TPEKLAPTTPEKPAPTTPE 605

Query: 1483 EYKESWGQPEAWEEKPTHELPRELGKRSPLTSPPENWGGPAESSQSWHSGTPT---AVGW 1539
            E   +        E+PT   P E    +P  + P     PA ++    + T     A   
Sbjct: 606  ELAPTT------PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 659

Query: 1540 GAEGACPYPRGSERRPELDWRDLLGLLRAPGEGVWARVPSLDWEGLLELLQARLPRKDPA 1599
              E A   P+G+                AP                       L    P 
Sbjct: 660  PKETAPTTPKGT----------------AP---------------------TTLKEPAPT 682

Query: 1600 GHRDDLARALGPELGPPGTNDVPEQESHSQPEGWAEATPVNGHSPALQSQSPVQLPSPAC 1659
              +    + L P      T+   ++ + + P+G A  TP        +  +P      A 
Sbjct: 683  TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 742

Query: 1660 TSTQWPKIKVTRGPATATLAGLEQTGPLGSRSTAKGPSLPELQFQPEEPEESEPSRGQDP 1719
            T+ + P     + PA   LA     GP  + S    P+ P+ +  P  P+E  P+  + P
Sbjct: 743  TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK-ETAPTTPKEPAPTTPKKP 801

Query: 1720 LTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDRPTLFNPFLLSLGVLRWRRPDLL- 1778
                 +       P   +  +P   +  T+     D  T                P+L  
Sbjct: 802  APTTPETPP----PTTSEVSTPTTTKEPTTIHKSPDEST----------------PELSA 841

Query: 1779 -NFKKGWMSILDEPGEPPS-------PSLTTTSTSQWKKHWFVLTDSSLKYYRDSTAEEA 1830
                K   +   EPG P +       P +TTT+  +  +     T  +       T E A
Sbjct: 842  EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETA 901

Query: 1831 DELDGEIDLR---SCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTVR 1887
               +   + +   + T VT    Q    F+I T         +T+          +KT+ 
Sbjct: 902  TTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTT---------TKKTIT 952

Query: 1888 PTSAPDVTKLSDSNKENALHSYSTQKGPLKAGEQRAGSEVISRGGPRKADGQRQALDYVE 1947
             T   +  + +   K+ A +S +T   P K               P KA  +  +    +
Sbjct: 953  TTEIMNKPEETAKPKDRATNSKATTPKPQK---------------PTKAPKKPTSTKKPK 997

Query: 1948 LSPLTQASPQRARTPARTPDRLAKQEELERDLAQRSEERRKWFEATDSRTPEV-PAGEGP 2006
              P  +  P+   TP +    + +     R      +   +  +  +S+  EV P  E  
Sbjct: 998  TMPRVR-KPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDA 1056

Query: 2007 RRGLGAPLTEDQQNRLSEEIEKKWQELEKLPLRENKRVPLTALLNQSRGERRGPPSDGHE 2066
                G   T     R    + +   +++ LP   N+ + +  +L+       G P DG  
Sbjct: 1057 GGAEGE--TPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETNICNGKPVDGLT 1114

Query: 2067 ALEKEVQALRAQLEAWRLQGEAPQSALR 2094
             L             W L   +P S  R
Sbjct: 1115 TLRNGTLVAFRGHYFWMLSPFSPPSPAR 1142



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 84/433 (19%), Positives = 142/433 (32%), Gaps = 69/433 (15%)

Query: 1325 QAQDEGRSQQPSQGQSQLLRRQSSP--APSRQVTMLPAKQAELTRRSQA----EPPHPWS 1378
            Q   +G+ +  S  ++Q + + S+   AP+ +V   P  +AE T +  A    + P P +
Sbjct: 254  QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT 313

Query: 1379 PEKRPEGDRQLQGSPLPPRTSARTPERELRTQRPLESGQAGPRQPLGVWQSQEEPPGSQG 1438
            P K P      + +P   +++  TP+    T    +S    P++P      +  P   + 
Sbjct: 314  P-KEPASTTPKEPTPTTIKSAPTTPKEPAPTTT--KSAPTTPKEPAPTTTKEPAPTTPKE 370

Query: 1439 PHRHLERSWSSQEGGLGPGGWWGCGEPSLGAAKAPEGAWGGTSREYKESWGQPEAWEEKP 1498
            P                         P+     AP       +   + +   P+    KP
Sbjct: 371  P------------------------APTTTKEPAPTTTKSAPTTPKEPAPTTPK----KP 402

Query: 1499 THELPRELGKRSPLTSPPENWGGPAESSQSWHSGTPTAVGWGAEGACPYPRGSERRPELD 1558
                P+E    +P    P     PA +++     TP           P P   ++     
Sbjct: 403  APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE---------PAPTAPKKPAPTT 453

Query: 1559 WRDLLGLLRAPGEGVWARVPSLDWEGLLELLQARLPRKDPAGHRDDLARALGPELGPPGT 1618
             ++              + PS                K+PA      A     E  P  T
Sbjct: 454  PKEPAPTTPKEPAPTTTKEPS------------PTTPKEPAPTTTKSAPTTTKEPAPTTT 501

Query: 1619 NDVPEQESHSQPEGWAEATPVNGHSPAL---QSQSPVQLPSPACTSTQWPKIKVTRGPAT 1675
               P       P    E  P     PA    +  +P     PA T+ + P    T+ PA 
Sbjct: 502  KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 561

Query: 1676 ATLAGLEQTGPLGSRSTAK---GPSLPELQFQPEEPEESEPSRGQD--PLTDQKQADSAD 1730
             T      T P  +  T      P+ PE +  P  PE+  P+  ++  P T ++   +  
Sbjct: 562  TTPKEPAPTTPKETAPTTPKKLTPTTPE-KLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 620

Query: 1731 KRPA--EGKAGSP 1741
            + PA    KA +P
Sbjct: 621  EEPAPTTPKAAAP 633


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 95.1 bits (235), Expect = 7e-19
 Identities = 160/849 (18%), Positives = 297/849 (34%), Gaps = 108/849 (12%)

Query: 228  ESGLSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQR 287
            ES    E H  +  Q SS +  S   S+T +   + +++A   + RE+ +        + 
Sbjct: 150  ESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSA---ANRELQKKLKVKDNKKN 206

Query: 288  DTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDT-PRASSTQWNTPRASSP- 345
             T +  + +  +   + +  +      T  DT      +  T P+ ++ +   PR S P 
Sbjct: 207  RTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPP 266

Query: 346  ----SRSTQLD-NPRTSSTQQDNPQTSFPTCTPQRENP----RTPCVQQDDPRASSPN-- 394
                S+ T L  N  T+   ++   T+  T T  +E       T  +++   +  +P   
Sbjct: 267  NSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 326

Query: 395  ---RTTQRENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNP 451
               + T +  + T       PK    ++P       P+           S+P+      P
Sbjct: 327  VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPK---EPTPTTIKSAPTTPKEPAP 383

Query: 452  TTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPR 511
            TT+   +  P   +  +P       P T       P+  +P+      PTT+ +    P+
Sbjct: 384  TTT---KSAPTTPKEPAPTTTKEPAPTT-------PKEPAPTTTKEPAPTTTKSAPTTPK 433

Query: 512  ASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRAT 571
                ++P +     P+        P+  +P       PTT       P+    ++P +  
Sbjct: 434  EPAPTTPKKPAPTTPKEPAP--TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 491

Query: 572  RDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQR 631
               P+        P+  +P      +PTT    ++    +  S+P       P T+ +  
Sbjct: 492  PTTPKEPAP--TTPKEPAPTTTKEPSPTT---PKEPAPTTTKSAPTTTKEPAPTTTKSAP 546

Query: 632  DNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTI 691
              P+  SP  TT++ +P T       P+  +P  T ++  P T            P+ T 
Sbjct: 547  TTPKEPSPT-TTKEPAPTT-------PKEPAPT-TPKKPAPTT---------PKEPAPTT 588

Query: 692  QQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQR 751
             +E   T+  +        P  TT +E   T+  ++  P    +      + P  +  + 
Sbjct: 589  PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT-PKKLTPTTPEKLAPTTPEKPAPTTPEE 647

Query: 752  DNPRA-SSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRAT 810
              P     P  T  +E   T+      P+ ++PN      P T            P   T
Sbjct: 648  LAPTTPEEPTPTTPEEPAPTT------PKAAAPNTPKEPAPTT---------PKEPAPTT 692

Query: 811  QQDNPRTCIQQNIPRSSSTQQDNPK-TSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSS 869
             ++   T  ++  P +       PK T+ T      PT  ++   +  +     P T+  
Sbjct: 693  PKEPAPTTPKETAPTT-------PKGTAPTTLKEPAPTTPKKPAPKELA-----PTTTKE 740

Query: 870  QCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQ 929
               T  +   P++P + T    P+  +P    +  P       PT    P  ++P +   
Sbjct: 741  PTSTTCDKPAPTTP-KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 799

Query: 930  SEV-PWASIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQST 988
             E+ P  +     T  D+P  ++P   A   P + +  PT    P+  T  +  P   +T
Sbjct: 800  KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPA--PTTPKKPAPTTPETPPP---TT 854

Query: 989  SRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPE 1048
            S  S+P           SP+ S P  +          A   P+ L++ P     EP  P 
Sbjct: 855  SEVSTPTTTKEPTTIHKSPDESTPELS----------AEPTPKALENSP----KEPGVPT 900

Query: 1049 SEPPHHEPP 1057
            ++ P    P
Sbjct: 901  TKTPAATKP 909



 Score = 79.3 bits (194), Expect = 4e-14
 Identities = 135/722 (18%), Positives = 249/722 (34%), Gaps = 98/722 (13%)

Query: 58   PAPEDPLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEE---------GPTA---APRSR 105
            PAP    SA T+  +       +P P     P+   P+E          PT    AP + 
Sbjct: 420  PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 479

Query: 106  SRELEAVPYLEGLTT--SLCGSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEE 163
                   P     TT      +  ++P    T  P   TP + + +++    T  +  E 
Sbjct: 480  KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK--EP 537

Query: 164  APSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWA 223
            AP+  + A   P  P+E     + + AP+    +P        KK               
Sbjct: 538  APTTTKSA---PTTPKEPSPTTTKEPAPT----TPKEPAPTTPKKPAP------------ 578

Query: 224  RLRGESGLSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHR 283
                          +T  + +  TP     +TT + +P       A +T +    ++P +
Sbjct: 579  --------------TTPKEPAPTTPKEPAPTTTKKPAPT-TPKEPAPTTPKETAPTTPKK 623

Query: 284  ITQRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRA-SSTQEDTPRASSTQWNTPRA 342
            +T     + + T  E  + + T  E    ++ +E TP         TP+A++   NTP+ 
Sbjct: 624  LTPTTPEKLAPTTPE--KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP--NTPKE 679

Query: 343  SSPS-----RSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTT 397
             +P+       T    P  ++ ++  P T   T     + P     ++  P+  +P  TT
Sbjct: 680  PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP--TT 737

Query: 398  QRENSRTSCAQ--RDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSC 455
             +E + T+C +     PK +  ++P       P+        P+ ++P+      PTT  
Sbjct: 738  TKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP--TTPKGTAPTTLKEPAPTTPK 795

Query: 456  AQRDNPRA-SRTSSPNRATRDNPRTSCAQRDNPRA-SSPSRATRDNPTTSCAQRDNPRAS 513
                   A + T  P   T D P  +  +   P     P+  T   P  +  +   P  S
Sbjct: 796  KPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS 855

Query: 514  RTSSPNRATRDNPRTSCAQRDNPRASS-PNRAARDN-------PTTSCAQRDNPRASRTS 565
              S+P                 P  S+ P   A +N       PTT       P  + T+
Sbjct: 856  EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA 915

Query: 566  SPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPN-------- 617
                  RD   T       P+ +     T +  T S       + + T++ +        
Sbjct: 916  KDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITT 975

Query: 618  -RATRDNPRTSCAQRDNPRASSPNRTTQQDSP--RTSCARRDDPR----ASSPNRTIQQE 670
             + T   P+ +  ++        N+  +   P  R + ++   P+      +P +    +
Sbjct: 976  LKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTK 1035

Query: 671  NPRTSCALRDNPRASSPSR---TIQQENPRTSCAQRDDPRASSPNRTTQQE----NPRTS 723
             P+T   +R      +P +   T+ + NP +  A+      + PN+T   +    NP++ 
Sbjct: 1036 KPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSE 1095

Query: 724  CA 725
             A
Sbjct: 1096 DA 1097



 Score = 78.6 bits (192), Expect = 7e-14
 Identities = 176/900 (19%), Positives = 290/900 (32%), Gaps = 97/900 (10%)

Query: 530  CAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASS 589
            CA+  NP  +SP  + +  P +  +Q       R+  P    +        +     + S
Sbjct: 104  CAEVHNP--TSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVS 161

Query: 590  PNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPR 649
             N+ +  + ++S +     +    SS N A     +     +DN +    NRT ++ +P+
Sbjct: 162  ENQESSSSSSSSSSSSTIRKIK--SSKNSAANRELQKKLKVKDNKK----NRTKKKPTPK 215

Query: 650  TSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRAS 709
                  D+  +   N   +   P TS    +    S    T +  NPR S     D    
Sbjct: 216  PPVV--DEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKE 273

Query: 710  SPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLR 769
            +     ++    T      N + S+  +        T   ++ + +  +P   +  +   
Sbjct: 274  TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP 333

Query: 770  TSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQ--NIPRSS 827
             + T    P  ++P   T   P+   +         P   T +  P T  +      +S+
Sbjct: 334  KAETTTKGPALTTPKEPTPTTPKEPASTTPK----EPTPTTIKSAPTTPKEPAPTTTKSA 389

Query: 828  STQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRST 887
             T    P  + TK     P  T        + +   P T+ S   T KE   P++P +  
Sbjct: 390  PTTPKEPAPTTTKE----PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA-PTTPKKPA 444

Query: 888  QWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRP 947
                P+  +P  T    P  + P  P     P T  P+ +   E         PT   +P
Sbjct: 445  P-TTPKEPAP--TTPKEPTPTTPKEPA----PTTKEPAPTTPKEPA-------PTAPKKP 490

Query: 948  QTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNP--GHQSTSRTSSPVYPAAYGAPLT 1005
              ++P  PA   P + +  PT    PS  T     P     + + T  P       AP T
Sbjct: 491  APTTPKEPAPTTPKEPA--PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 548

Query: 1006 SPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESEPPHHEPPYIP--PAV 1063
              EPS                  P      +P P  P+  AP +  P    P  P  PA 
Sbjct: 549  PKEPS------------PTTTKEPAPTTPKEPAPTTPKKPAPTT--PKEPAPTTPKEPAP 594

Query: 1064 CIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRAS 1123
                + AP        T  +P P    T+  E    +P+      P  +     + P  +
Sbjct: 595  TTTKKPAPT-------TPKEPAP----TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPT 643

Query: 1124 SPPRQAP----EPSLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPR 1179
            +P   AP    EP+    + P  +T             P  P          P+ ++P  
Sbjct: 644  TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKE 703

Query: 1180 QAPEPSLFFQDPPGTSMESL---APSTDSLHGSPVLIPQVCIGHRDAPRASSPPRHPPSD 1236
             AP        P GT+  +L   AP+T        L P               P  P   
Sbjct: 704  TAP------TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 757

Query: 1237 LAFLAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVLADLPPPRRLA-QRQPGPQAQCSS 1295
                   P+P +      + P G     L +E        P P+ LA     GP +  S 
Sbjct: 758  APTTPKEPAPTTPKEPAPTTPKGTAPTTL-KEPAPTTPKKPAPKELAPTTTKGPTSTTSD 816

Query: 1296 GGRTHSPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPSRQV 1355
                 +P              K  A    +       + P    S++    S+P  +++ 
Sbjct: 817  KPAPTTPKET------APTTPKEPAPTTPKKPAPTTPETPPPTTSEV----STPTTTKEP 866

Query: 1356 TMLPAKQAELTRRSQAEPPHPW---SPEKRPEGDRQLQGSPLPPRTSA---RTPERELRT 1409
            T +     E T    AEP       SP++      +   +  P  T+    +T ER+LRT
Sbjct: 867  TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 926



 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 102/552 (18%), Positives = 190/552 (34%), Gaps = 48/552 (8%)

Query: 42   SPSGAEVPYCDLPRCPPAPEDPLS-ASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTA 100
            SP+  + P    P+  PAP  P   A T+  +        P P     P+   P+E    
Sbjct: 553  SPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 611

Query: 101  APRSRSRELEAVPYLEGLTTSLCGSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQ 160
             P+      E  P        L  +  E         P   TP++ + ++  +  T    
Sbjct: 612  TPK------ETAPTTP---KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE-PTPTTP 661

Query: 161  EEEAPSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQ 220
            EE AP+  + A   P  P+E       + AP+   + P              G   +  +
Sbjct: 662  EEPAPTTPKAAA--PNTPKEPAPTTPKEPAPTT-PKEPAPTTPKETAPTTPKGTAPTTLK 718

Query: 221  HWARLRGESGLSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASS 280
              A    +     E   +T  + +S T    P  TT + +        A +T + P  ++
Sbjct: 719  EPAPTTPKKPAPKELAPTTTKEPTSTTCDK-PAPTTPKGTAPTTPKEPAPTTPKEPAPTT 777

Query: 281  PHRITQRDTSR-ASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNT 339
            P           A +T ++ +        T   +ST  D P  ++ +E  P        T
Sbjct: 778  PKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP-------TT 830

Query: 340  PRASSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQR 399
            P+  +P+   +       +T +  P T+    TP     + P      P  S+P  + + 
Sbjct: 831  PKEPAPTTPKK----PAPTTPETPPPTTSEVSTP--TTTKEPTTIHKSPDESTPELSAE- 883

Query: 400  ENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNP-TTSCAQR 458
                T  A  ++PK     +        P  +   +D     +  R  R  P TT+ A +
Sbjct: 884  ---PTPKALENSPKEPGVPTTKTPAATKPEMTTTAKD----KTTERDLRTTPETTTAAPK 936

Query: 459  DNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSS- 517
                 + T+     ++    T+       + ++P + T    TT   +    + + T++ 
Sbjct: 937  MTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE 996

Query: 518  ----PNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASR---TSSPNRA 570
                P    +   R + ++   P+   P +A +  PT++   +  PR  +   T +P + 
Sbjct: 997  IMNKPEETAKPKDRATNSKATTPKPQKPTKAPK-KPTSTKKPKTMPRVRKPKTTPTPRKM 1055

Query: 571  TRDNPRTSCAQR 582
            T   P  +   R
Sbjct: 1056 TSTMPELNPTSR 1067



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 182/988 (18%), Positives = 308/988 (31%), Gaps = 148/988 (14%)

Query: 1129 APEPSLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFF 1188
            AP   +L +  P+A T +  P++ +    P  PTP        P+ ++P    P      
Sbjct: 322  APTSKVLAKPTPKAETTTKGPALTT----PKEPTPTT---PKEPASTTPKEPTPTT---I 371

Query: 1189 QDPPGTSMESLAPSTDSLHGSPVLIPQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGS 1248
            +  P T  E    +T S   +P            AP  +  P   P+     AP+ +   
Sbjct: 372  KSAPTTPKEPAPTTTKSAPTTP---------KEPAPTTTKEPA--PTTPKEPAPTTTKEP 420

Query: 1249 SGGSRGSAP--PGETRHNLEREEYTVLADLPPPRRLAQRQPGPQAQCSSGGRTHSPGRAE 1306
            +  +  SAP  P E      ++        P P     ++P P         T  P    
Sbjct: 421  APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT--TPKEPTPTTPKEPAPTTKEPAPTT 478

Query: 1307 VERLFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPSRQVTMLPAKQAELT 1366
             +       +K     A     E     P +  +    ++ SP   ++      K A  T
Sbjct: 479  PKEPAPTAPKKP----APTTPKEPAPTTPKE-PAPTTTKEPSPTTPKEPAPTTTKSAPTT 533

Query: 1367 RRSQAEPPHPWSPE--KRPEGDRQLQGSPLPPRTSARTPERELRTQRPLESGQAGPRQPL 1424
             +  A      +P   K P      + +P  P+  A T  ++     P E     P++P 
Sbjct: 534  TKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 593

Query: 1425 GVWQSQEEP--PGSQGPHRHLERSWSSQEGGLGPGGWWGCGEPSLGAAKAPEGAWGGTSR 1482
                 +  P  P    P    E + ++ +  L P        P   A   PE     T  
Sbjct: 594  PTTTKKPAPTTPKEPAPTTPKETAPTTPKK-LTPT------TPEKLAPTTPEKPAPTTPE 646

Query: 1483 EYKESWGQPEAWEEKPTHELPRELGKRSPLTSPPENWGGPAESSQSWHSGTPT---AVGW 1539
            E   +        E+PT   P E    +P  + P     PA ++    + T     A   
Sbjct: 647  ELAPTT------PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 700

Query: 1540 GAEGACPYPRGSERRPELDWRDLLGLLRAPGEGVWARVPSLDWEGLLELLQARLPRKDPA 1599
              E A   P+G+                AP                       L    P 
Sbjct: 701  PKETAPTTPKGT----------------AP---------------------TTLKEPAPT 723

Query: 1600 GHRDDLARALGPELGPPGTNDVPEQESHSQPEGWAEATPVNGHSPALQSQSPVQLPSPAC 1659
              +    + L P      T+   ++ + + P+G A  TP        +  +P      A 
Sbjct: 724  TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 783

Query: 1660 TSTQWPKIKVTRGPATATLAGLEQTGPLGSRSTAKGPSLPELQFQPEEPEESEPSRGQDP 1719
            T+ + P     + PA   LA     GP  + S    P+ P+ +  P  P+E  P+  + P
Sbjct: 784  TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK-ETAPTTPKEPAPTTPKKP 842

Query: 1720 LTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDRPTLFNPFLLSLGVLRWRRPDLL- 1778
                 +       P   +  +P   +  T+     D  T                P+L  
Sbjct: 843  APTTPETPP----PTTSEVSTPTTTKEPTTIHKSPDEST----------------PELSA 882

Query: 1779 -NFKKGWMSILDEPGEPPS-------PSLTTTSTSQWKKHWFVLTDSSLKYYRDSTAEEA 1830
                K   +   EPG P +       P +TTT+  +  +     T  +       T E A
Sbjct: 883  EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETA 942

Query: 1831 DELDGEIDLR---SCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTVR 1887
               +   + +   + T VT    Q    F+I T         +T+          +KT+ 
Sbjct: 943  TTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTT---------TKKTIT 993

Query: 1888 PTSAPDVTKLSDSNKENALHSYSTQKGPLKAGEQRAGSEVISRGGPRKADGQRQALDYVE 1947
             T   +  + +   K+ A +S +T   P K               P KA  +  +    +
Sbjct: 994  TTEIMNKPEETAKPKDRATNSKATTPKPQK---------------PTKAPKKPTSTKKPK 1038

Query: 1948 LSPLTQASPQRARTPARTPDRLAKQEELERDLAQRSEERRKWFEATDSRTPEV-PAGEGP 2006
              P  +  P+   TP +    + +     R      +   +  +  +S+  EV P  E  
Sbjct: 1039 TMPRVR-KPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDA 1097

Query: 2007 RRGLGAPLTEDQQNRLSEEIEKKWQELEKLPLRENKRVPLTALLNQSRGERRGPPSDGHE 2066
                G   T     R    + +   +++ LP   N+ + +  +L+       G P DG  
Sbjct: 1098 GGAEGE--TPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETNICNGKPVDGLT 1155

Query: 2067 ALEKEVQALRAQLEAWRLQGEAPQSALR 2094
             L             W L   +P S  R
Sbjct: 1156 TLRNGTLVAFRGHYFWMLSPFSPPSPAR 1183



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 84/433 (19%), Positives = 142/433 (32%), Gaps = 69/433 (15%)

Query: 1325 QAQDEGRSQQPSQGQSQLLRRQSSP--APSRQVTMLPAKQAELTRRSQA----EPPHPWS 1378
            Q   +G+ +  S  ++Q + + S+   AP+ +V   P  +AE T +  A    + P P +
Sbjct: 295  QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTT 354

Query: 1379 PEKRPEGDRQLQGSPLPPRTSARTPERELRTQRPLESGQAGPRQPLGVWQSQEEPPGSQG 1438
            P K P      + +P   +++  TP+    T    +S    P++P      +  P   + 
Sbjct: 355  P-KEPASTTPKEPTPTTIKSAPTTPKEPAPTTT--KSAPTTPKEPAPTTTKEPAPTTPKE 411

Query: 1439 PHRHLERSWSSQEGGLGPGGWWGCGEPSLGAAKAPEGAWGGTSREYKESWGQPEAWEEKP 1498
            P                         P+     AP       +   + +   P+    KP
Sbjct: 412  P------------------------APTTTKEPAPTTTKSAPTTPKEPAPTTPK----KP 443

Query: 1499 THELPRELGKRSPLTSPPENWGGPAESSQSWHSGTPTAVGWGAEGACPYPRGSERRPELD 1558
                P+E    +P    P     PA +++     TP           P P   ++     
Sbjct: 444  APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE---------PAPTAPKKPAPTT 494

Query: 1559 WRDLLGLLRAPGEGVWARVPSLDWEGLLELLQARLPRKDPAGHRDDLARALGPELGPPGT 1618
             ++              + PS                K+PA      A     E  P  T
Sbjct: 495  PKEPAPTTPKEPAPTTTKEPS------------PTTPKEPAPTTTKSAPTTTKEPAPTTT 542

Query: 1619 NDVPEQESHSQPEGWAEATPVNGHSPAL---QSQSPVQLPSPACTSTQWPKIKVTRGPAT 1675
               P       P    E  P     PA    +  +P     PA T+ + P    T+ PA 
Sbjct: 543  KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 602

Query: 1676 ATLAGLEQTGPLGSRSTAK---GPSLPELQFQPEEPEESEPSRGQD--PLTDQKQADSAD 1730
             T      T P  +  T      P+ PE +  P  PE+  P+  ++  P T ++   +  
Sbjct: 603  TTPKEPAPTTPKETAPTTPKKLTPTTPE-KLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 661

Query: 1731 KRPA--EGKAGSP 1741
            + PA    KA +P
Sbjct: 662  EEPAPTTPKAAAP 674


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 93.2 bits (230), Expect = 3e-18
 Identities = 260/1102 (23%), Positives = 354/1102 (32%), Gaps = 209/1102 (18%)

Query: 489  ASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPR-ASSPNRAARD 547
            A+ P  A R  PT S        ASR  +  R  R  P    A+  +P   SSP RA+  
Sbjct: 68   ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPP----AKNTSPGPVSSPGRASGT 123

Query: 548  NPTTSCAQRD-NPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRD 606
                   Q+     A  T +  +AT    R++ +       S P   T   P+ + A+R 
Sbjct: 124  TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT---PSPAMARRS 180

Query: 607  NPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRT 666
                +    P  A    PR          +S+   +T + SP    A R  P A    + 
Sbjct: 181  RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP----AARRRPSAGGGLQR 236

Query: 667  IQQENPRTSCALRDNPRASSPSRTIQQENPRTSC-AQRDDPRASSPNRTTQQENPRTSCA 725
                +  +S     +P  S PS    +  PR      +  P+     R  Q   PR   A
Sbjct: 237  PASRSLSSSATPLSSPARSGPSA---RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 293

Query: 726  RRDNPRASSRNRTIQRDNPRTS-CAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPN 784
                P +SS   T      +       DN     P        L T         ++ P+
Sbjct: 294  PALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPS 353

Query: 785  RATRDNP-RTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTKRDN 843
              T  +P  T  +Q      + P++A         IQ  +P S ++       S     +
Sbjct: 354  LQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQ--VPHSLTSPSLQAPPSPLALSS 411

Query: 844  LRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKD 903
            L+ T +    T     Q  +   + S   TQ     PS P      + P +S P +    
Sbjct: 412  LQATTSLGSPT----LQATHSFLTMSPRQTQASLTSPSRPA-----STPPDSPPLQAPLS 462

Query: 904  IPWASFPLRPTQS------DGPRTSSPSRSKQS------EVPWASIALRPTQGDRPQTSS 951
            +P AS PL+ + S        P T  P ++  S      + P +S+ + P +      SS
Sbjct: 463  LP-ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQ----SS 517

Query: 952  PSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQ 1011
             + P+   PP S   P   NLPS A      P  Q+ S            APLT+P    
Sbjct: 518  LAPPSLQTPPASLTTPPLENLPSLAP-----PPLQTAS------------APLTTPHLET 560

Query: 1012 PPCAVCIGHRDAPRASSPPRYLQHDPFPFF-PEPRAPESEPPHHEPPYIPPAVCIGHRDA 1070
            PPC               P  LQ  P P   P P  P S      PP  PPA+       
Sbjct: 561  PPCPA-------------PCPLQAPPSPLTTPPPETPSSIAT--PPPQAPPAL------- 598

Query: 1071 PRASSPPRHTQFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRASSPPRQAP 1130
               +SPP          LP          SP   PL  P P        P   +PP    
Sbjct: 599  ---ASPPLQG-------LP----------SPPLSPLATPPPQAPPXLALPPLQAPPSPPA 638

Query: 1131 EPSLLFQDLPRASTESLVPSMDSLH--ECPHIPTPVCIGHRDAPSFSSPPRQAP------ 1182
             P L     P A+     P+  ++H  + P  P P            SPP QAP      
Sbjct: 639  SPPLS----PLATPSPQAPNALAVHLLQAPFSPPP------------SPPVQAPFSPPAS 682

Query: 1183 EPSLFFQDPPGTSMESLAPSTDSLHGSPVLIPQVCIGHRDAPRASSPPRHPPSDLA---F 1239
             P      PP  +  SLA     +  SP   P +      +P A+ PP+ PP   A    
Sbjct: 683  PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM------SPSATPPPQAPPPLAAPPLQ 736

Query: 1240 LAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVLADLPPPRRLAQRQPGPQAQCSSGGRT 1299
            + PSP P S   S  + PP              L   PP     Q  P P A        
Sbjct: 737  VPPSP-PASPPMSPSATPPPRV---------PPLLAAPP----LQVPPSPPASLPMSPLA 782

Query: 1300 HSPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPSRQVTMLP 1359
              P +A            + A    QA     +  P Q            +PS  + M P
Sbjct: 783  KPPPQAP----------PALATPPLQALPSPPASFPGQAPF---------SPSASLPMSP 823

Query: 1360 AKQAELTRRSQAEPPHPWSPEKRPE-GDRQLQGSPLPPRTSARTPERELRTQRPLESGQA 1418
                       A PP    P+  P      LQ  P PP +      R   T  P ++  +
Sbjct: 824  L----------ATPP----PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP-DTSVS 868

Query: 1419 GPRQPLGVWQSQEEPPGSQGPHRHLERSWSSQEGGLGPGGWWGCG----EPSLGAAKAPE 1474
            GPR  L +      PP          RS SS   G    G         E   G    PE
Sbjct: 869  GPRLTLALAPGPPPPPS---------RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 919

Query: 1475 GAWGGTSREYKESWG-QPEAWEEKPTHELPRELGKRSPLTSPPENWGGPAESSQSWHSGT 1533
            G    +     E     P AW   P   L       +PL  PP    G A+   + +   
Sbjct: 920  GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETE 979

Query: 1534 PTAVGWGAEGACPYPRGSERRP 1555
                  G E A P P   +  P
Sbjct: 980  ------GPESATPAPGALDPGP 995



 Score = 82.8 bits (203), Expect = 4e-15
 Identities = 210/857 (24%), Positives = 282/857 (32%), Gaps = 134/857 (15%)

Query: 649  RTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRT---SCAQRDD 705
            RT  AR        P  + +   P T  ALR    A +  R    E       +      
Sbjct: 15   RTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74

Query: 706  PRASSPNRT--TQQENPRTSCARRDNPRASSRNRTIQRDNP--RTSCAQRDNP-RASSPN 760
            PRA  P R+  T   NP +       P AS R    +R  P   TS     +P RAS   
Sbjct: 75   PRAG-PTRSAGTSSRNPAS------RPPASGRG---ERAPPAKNTSPGPVSSPGRASGTT 124

Query: 761  RT--IQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRAS--SPIRATQQDNPR 816
            R   + Q+ LR S   ++         A + +  ++ A+RD    +  +P  A  + +  
Sbjct: 125  RPGPLGQKGLRISA--EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 182

Query: 817  TCIQQNIPRSSSTQQDNPKT--------SCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSS 868
               +  +PR + + +  P T        S ++     P+   R R  +    +     S 
Sbjct: 183  AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242

Query: 869  SQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPR-------- 920
            S   T       SSP RS         +P   ++  P     LRP Q   PR        
Sbjct: 243  SSSATPL-----SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 297

Query: 921  --------TSSPSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNL 972
                    T SPS +K   VP    A  P     P +   + P    PP  S  P+   L
Sbjct: 298  PLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTL 357

Query: 973  PS-RATSSSHNPGHQSTSRTSSP-----VYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRA 1026
            PS  AT  S  P   +T    +P     + P      LTSP    PP  + +    A  +
Sbjct: 358  PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS 417

Query: 1027 -SSPPRYLQHDPFPFFP--------EPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPP 1077
              SP     H      P         P  P S PP   P   P ++          +SPP
Sbjct: 418  LGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSL---------PASPP 468

Query: 1078 RHTQFDP-----------FPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRASSPP 1126
              T   P            P    +S A H  Q+P    L +P          P   +PP
Sbjct: 469  LQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPL-SSLIMPPLETQSSLAPPSLQTPP 527

Query: 1127 RQAPEPSLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQAPEPSL 1186
                 P L  ++LP  +   L  +   L   PH+ TP C     AP     P QAP PS 
Sbjct: 528  ASLTTPPL--ENLPSLAPPPLQTASAPL-TTPHLETPPC----PAPC----PLQAP-PSP 575

Query: 1187 FFQDPPGT--SMESLAPSTDSLHGSPVL--IPQVCIGHRDAPRASSPPRHPPS-DLAFLA 1241
                PP T  S+ +  P       SP L  +P   +    +P A+ PP+ PP   L  L 
Sbjct: 576  LTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPL----SPLATPPPQAPPXLALPPLQ 631

Query: 1242 PSPSPGSSGGSRGSAPPGETRHNLEREEYTVLADLPPPRRLAQRQPGPQAQCSSGGRTHS 1301
              PSP +S      A P     N            PPP    Q    P A          
Sbjct: 632  APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 691

Query: 1302 PGRAEVERLFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPSRQVTMLPAK 1361
            P +A            S AA   Q         PS   S  +   ++P P +    L A 
Sbjct: 692  PSQAP----------PSLAAPPLQV-------PPSPPASPPMSPSATP-PPQAPPPLAAP 733

Query: 1362 QAELTRRSQAEPPHPWSPEKRPEGDRQLQGSPL--PPRTSARTPERELRTQRPLESGQAG 1419
              ++     A PP   S    P     L   PL  PP   A  P   L    P    QA 
Sbjct: 734  PLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP----QAP 789

Query: 1420 PRQPLGVWQSQEEPPGS 1436
            P       Q+   PP S
Sbjct: 790  PALATPPLQALPSPPAS 806



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 242/1035 (23%), Positives = 354/1035 (34%), Gaps = 185/1035 (17%)

Query: 355  RTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSR-------TSCA 407
            RT + +     T  P  +P+   P TP   +    A +  R    E +           A
Sbjct: 15   RTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74

Query: 408  QRDNP-KASRTSSPNRATRDNPRTSCAQRDNPR-------ASSPSRA---TRDNPTTSCA 456
             R  P +++ TSS N A+R  P +   +R  P         SSP RA   TR  P     
Sbjct: 75   PRAGPTRSAGTSSRNPASRP-PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 133

Query: 457  QRDNPRASRTSSPNRATRDNPRTSC---AQRDN--PRASSPSRATRDNPTTSCAQRDNPR 511
             R +  A  T +  +AT    R++    A+RD   P   +PS A       +  +   PR
Sbjct: 134  LRIS--AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 191

Query: 512  ASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCA-QRDNPRASRTSSPNRA 570
             + ++ P   T + PR S +       + P+ AAR  P+     QR    ASR+ S +  
Sbjct: 192  PAPSARPRPPT-EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP---ASRSLSSSAT 247

Query: 571  TRDNP-RTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCA 629
               +P R+  + R  PRA +       +P+     +  P+  +   P + T   PR   A
Sbjct: 248  PLSSPARSGPSARGTPRAPA-------HPS-----QPKPKGLQALRPPQVTP--PRKDAA 293

Query: 630  QRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENP-RTSCALRDNPRASSPS 688
                P +SSP  T      +       D  A+    T+    P  T   L     ++ PS
Sbjct: 294  PALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPS 353

Query: 689  RTIQQENPRTSCAQRDD-----PRASSPNRTT----QQENPRTSCARRDNPRA---SSRN 736
                   P T  +Q        P  + P+  T    Q  +  TS + +  P     SS  
Sbjct: 354  LQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQ 413

Query: 737  RTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCA 796
             T    +P        +    SP +T  Q +L +       P  S P +A    P +   
Sbjct: 414  ATTSLGSPTLQATH--SFLTMSPRQT--QASLTSPSRPASTPPDSPPLQAPLSLPASPPL 469

Query: 797  QRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQS 856
            Q     A SP+ +    +P   +       SS    +P+   +    + P    +     
Sbjct: 470  QTSLSPAVSPLSSPLTIHPLQAL-------SSLASHSPQAPLSSL--IMPPLETQSSLAP 520

Query: 857  FSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLR---- 912
             S Q       +S      ENL PS      Q  +   ++PH      P A  PL+    
Sbjct: 521  PSLQTP----PASLTTPPLENL-PSLAPPPLQTASAPLTTPHLETPPCP-APCPLQAPPS 574

Query: 913  PTQSDGPRTSSPSRSKQSEVPWASIALRPTQG-DRPQTSSPSRPAQHDPPQSSFGPTQYN 971
            P  +  P T S   +   + P A +A  P QG   P  S  + P    PP  +  P Q  
Sbjct: 575  PLTTPPPETPSSIATPPPQAPPA-LASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAP 633

Query: 972  LPSRAT---SSSHNPGHQSTSRTSSPVYPAAYGAPLTSP--EPSQPPCAVCIGHRDAPRA 1026
                A+   S    P  Q+ +  +  +  A +  P + P   P  PP +  +     P +
Sbjct: 634  PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 693

Query: 1027 SSPPRY----LQHDPFPFFPEPRAPESEPPHHEPP-------YIPPAVCIGHRDAPRASS 1075
             +PP      LQ  P P    P +P + PP   PP        +PP+       +P A+ 
Sbjct: 694  QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATP 753

Query: 1076 PPR--------HTQFDPFP--FLPDTSDAEHQCQSPQH---EPLQ-LPAPVCIGYRDAPR 1121
            PPR          Q  P P   LP +  A+   Q+P      PLQ LP+P       AP 
Sbjct: 754  PPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 813

Query: 1122 ASS----------PPRQAPE----PSLLFQDLPRAST------ESLVPSMDSLHECPHIP 1161
            + S          PP QAP     P L     P AS           P  D+    P + 
Sbjct: 814  SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT 873

Query: 1162 TPVCIGHRDAPSFS------------------SPPRQ------APEPSLFFQDPPGTSME 1197
              +  G    PS S                  S P +       PE       PP   + 
Sbjct: 874  LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA 933

Query: 1198 SLAPSTDSLHGSPVLIPQVCIGHRDAPRASSP---------------------PRHPPSD 1236
            +  P+  S   +P L        R AP A  P                     P      
Sbjct: 934  ACHPAAWSRGPAPPL------AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPA 987

Query: 1237 LAFLAPSPSPGSSGG 1251
               L P PSPG+SGG
Sbjct: 988  PGALDPGPSPGTSGG 1002



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 104/465 (22%), Positives = 152/465 (32%), Gaps = 67/465 (14%)

Query: 63  PLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTAAPRSRSRELEAVPYLEGLTTSL 122
           PL+    G      P     P+ GP+ SAG     P + P +  R   A P         
Sbjct: 57  PLAERAGGIGGATIP--ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPP--------- 105

Query: 123 CGSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRP--RE 180
             + N  PG  P SSP  A+   T+    +    +    EE  +  + A   P+R     
Sbjct: 106 --AKNTSPG--PVSSPGRAS--GTTRPGPLGQKGLRISAEETVARGK-ATEAPKRSALSA 158

Query: 181 GPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRSTL 240
           G R D+S   P   T SP                 R+AG        E GL         
Sbjct: 159 GARRDTSGPTPG--TPSPA-----------MARRSRAAGT-------EVGLP-----RPA 193

Query: 241 TQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEIS 300
             A    P  GPR + S AS         A+ R         R   R  S +++     +
Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253

Query: 301 RASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQ 360
           R+  + + T RA +               P+ +  + +   A  P  S+ L  P  S T+
Sbjct: 254 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTK 313

Query: 361 ------QDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQ------ 408
                  DN  T  P   P      TP        ++ P+  T      T  +Q      
Sbjct: 314 ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMT 373

Query: 409 ---RDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRD--NPT---TSCAQRDN 460
                 P + +T  P +        S     +P A S  +AT    +PT   T      +
Sbjct: 374 TPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMS 433

Query: 461 PRASRTS--SPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTS 503
           PR ++ S  SP+R     P +   Q      +SP   T  +P  S
Sbjct: 434 PRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVS 478



 Score = 33.9 bits (76), Expect = 1.9
 Identities = 27/96 (28%), Positives = 41/96 (42%), Gaps = 4/96 (4%)

Query: 49  PYCDLPRCP---PAPEDPLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTAAPRSR 105
           P   LP  P   P P+ P + +T   Q++  P      +   SPSA LP   P A P  +
Sbjct: 772 PPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS-PLATPPPQ 830

Query: 106 SRELEAVPYLEGLTTSLCGSCNEDPGSDPTSSPDSA 141
           +  + A P L+   +       + P   PT  PD++
Sbjct: 831 APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 866



 Score = 33.9 bits (76), Expect = 1.9
 Identities = 48/197 (24%), Positives = 62/197 (31%), Gaps = 32/197 (16%)

Query: 43   PSGAEVPYCDLPRCPPAPEDPLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPE-EGPTAA 101
            PS    P    PR PP P    S S       + PG  P P R PS +   P+  G +++
Sbjct: 844  PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 903

Query: 102  PRSRSRELEAVPYLEGLTTSLCGSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQE 161
              S   EL    Y  G       S        P    + A     + S         R  
Sbjct: 904  ATSTPEELRG--YDSGPEGGAAAS--------PPPDAELAACHPAAWSRGPAPPLAFRGA 953

Query: 162  EEAPSWDELAVMIPRRPREGPRA-------------DSSQRAPSLLTRSPVGGDAAGQKK 208
              AP        +P  P  GP +             +S+  AP  L   P  G + G+  
Sbjct: 954  PGAP--------LPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAA 1005

Query: 209  EDTGGGGRSAGQHWARL 225
               G G  S     ARL
Sbjct: 1006 AGAGAGASSRSPKQARL 1022



 Score = 31.6 bits (70), Expect = 9.7
 Identities = 24/76 (31%), Positives = 32/76 (42%), Gaps = 2/76 (2%)

Query: 41  RSPSGAEVPYCDLPRCPPAPEDPLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTA 100
           ++P     P   +P  PPA   P+S S +       P   P  +  PSP A  P   P+A
Sbjct: 694 QAPPSLAAPPLQVPPSPPA-SPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS-PPMSPSA 751

Query: 101 APRSRSRELEAVPYLE 116
            P  R   L A P L+
Sbjct: 752 TPPPRVPPLLAAPPLQ 767


>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
          Length = 2089

 Score = 92.4 bits (228), Expect = 5e-18
 Identities = 242/1129 (21%), Positives = 384/1129 (34%), Gaps = 163/1129 (14%)

Query: 134  PTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPRE--GP-RADSSQRA 190
            P  SP  A P D    S V  + +  Q     + D++ + IP+   E  GP R    +  
Sbjct: 777  PCLSPPRAIPGDQHPESPVHTEPMGIQGRGRQTVDKV-MGIPKETAERVGPERGPLERET 835

Query: 191  PSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWAR--------LRGESGLSLERHRSTLTQ 242
              LL       D  G+++   G   R   Q  AR          GES  S ER R +L  
Sbjct: 836  EKLLPERQT--DVTGEEELTKGKQDREQKQLLARDTQRQESDKNGESA-SPERDRESLKV 892

Query: 243  ASSMTPHSGPRSTTSQASPA---QRDTAQAASTREIPRASS----PHRITQRDTSRAS-- 293
                +     +    Q  P+   +R+  +  + RE   A      P  I +RDT R    
Sbjct: 893  EIETSEEIQEKQVQKQTLPSKAFEREVERPVANRECDPAELEEKVPKVILERDTQRGEPE 952

Query: 294  -STQQEISRASSTQQE------------TSRASSTQEDTPRASSTQEDTPRASSTQWNTP 340
              +Q +  +ASS   E            ++   S  +   R S       +        P
Sbjct: 953  GGSQDQKGQASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMP 1012

Query: 341  RASSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENP-RTPCVQQDDPRASSPNRTTQR 399
             A   SR    +  + S   Q++P    P   P+   P + P   Q     + P   +  
Sbjct: 1013 PAEKASRIRAAE--KVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLS-- 1068

Query: 400  ENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRD 459
                        P         R TR +       ++ P A   S     +P      R 
Sbjct: 1069 ------------PLLPSIKPTVRKTRQD-----GSQEAPEAPLSSELEPFHPKPKIRTRK 1111

Query: 460  NPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDN--------PTTSCAQRDNPR 511
            + R +   + + A   +P TS AQ   P+ +S +  +R N        P    A    P 
Sbjct: 1112 SSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPS 1171

Query: 512  ASR----TSSP-NRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSS 566
             S     TS P ++ TR   R S +    P    P  A    P+TS    D P  S  +S
Sbjct: 1172 TSTDQPVTSEPTSQVTRG--RKSRSSVKTPETVVPT-ALELQPSTS---TDRPVTSEPTS 1225

Query: 567  PNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRT 626
              +ATR     S  +   P   +   A    P+TS  Q      +  ++  R  R + +T
Sbjct: 1226 --QATRGRKNRSSVKTPEPVVPT---APELQPSTSTDQPVTSEPTYQATRGRKNRSSVKT 1280

Query: 627  -----SCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDN 681
                   A    P  S+    T + + RT+ +R +     +P   +            D 
Sbjct: 1281 PEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQ 1340

Query: 682  PRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQR 741
            P   +P  T +    RT+ +   +P ++ P     +  P TS  +   P  +S       
Sbjct: 1341 P--VTPKPTSRTTRSRTNMSSVKNPESTVP--IAPELPPSTSTEQPVTPEPTS------- 1389

Query: 742  DNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSP---------NRATRDNPR 792
               R +  +++     +P   +         T  D P T  P         NR++   P 
Sbjct: 1390 ---RATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPE 1446

Query: 793  TSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRD 852
            T       L+ S+     Q   P    Q    R+  +    P+T       L+ + +   
Sbjct: 1447 TVVPTAPELQPST--STDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQ 1504

Query: 853  RTQSFSFQRDNPGTSSSQCCTQKENLRPSSP--HRSTQWNNPRNSSP---------HRTN 901
               S    R   G  +       E + P++P    ST  + P    P         +R++
Sbjct: 1505 PVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSS 1564

Query: 902  KDIPWASFPLRP-----TQSDGPRTSSP-SRSKQSEVPWASIALRPTQGDRPQTSSPSRP 955
               P +  P+ P     T  +   T  P SR+ +     +S+         P+   P+ P
Sbjct: 1565 VKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSV-------KTPEPVVPTAP 1617

Query: 956  AQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYG-APLTSPEPSQPPC 1014
              H P  S+  P    L SRAT    N   +S+ +T  PV PAA    P T  + S  P 
Sbjct: 1618 EPH-PTTSTDQPVTPKLTSRATRRKTN---RSSVKTPKPVEPAASDLEPFTPTDQSVTPE 1673

Query: 1015 AVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRAS 1074
            A+  G +     SS  R +   P P  PE ++P +      P  I    CI  +   RA+
Sbjct: 1674 AIAQGGQSKTLRSSTVRAM---PVPTTPEFQSPVTTDQPISPEPITQPSCIKRQ---RAA 1727

Query: 1075 SPPRHTQFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRASSPPRQAPEPS- 1133
              P  +   P    P ++  E + Q+ +++              A RA+      PEP+ 
Sbjct: 1728 GNP-GSLAAPIDHKPCSAPLEPKSQASRNQRW-----------GAVRAAESLTAIPEPAS 1775

Query: 1134 --LLFQDLPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQ 1180
              LL   +  +  + + P+  S       P       R   +  SPP Q
Sbjct: 1776 PQLLETPIHASQIQKVEPAGRSRFTPELQPKASQSRKRSLATMDSPPHQ 1824



 Score = 37.4 bits (85), Expect = 0.18
 Identities = 121/551 (21%), Positives = 185/551 (33%), Gaps = 70/551 (12%)

Query: 1225 RASSPPRHP---PSDLAFLAPSPSP-GSSGGSRGSA---------------PPGETRHNL 1265
            +ASSP   P     DL     +P P GS  G RGS                PP E    +
Sbjct: 961  QASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRI 1020

Query: 1266 EREEYTVLAD-------LPPPRRLAQRQPGPQAQCSSGGRTHSPGRAEVERLFGQER--- 1315
               E     D       LPP   + +    PQ   +S  + H      +  L    +   
Sbjct: 1021 RAAEKVSRGDQESPDACLPPT--VPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTV 1078

Query: 1316 RKSEAAGAFQAQDEGRSQQ--PSQGQSQLLRRQSSPAPSRQVTMLPAKQAELTRRSQAEP 1373
            RK+   G+ +A +   S +  P   + ++  R+SS       T    +    T  +Q   
Sbjct: 1079 RKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVT 1138

Query: 1374 PHPWSPEKRPEGDRQLQGSPLPPRTSARTPERELRTQRPLESGQAGPRQPLGVWQSQEEP 1433
            P P S   R   +R    +P P   +A   +    T +P+ S            +S  + 
Sbjct: 1139 PKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKT 1198

Query: 1434 PGSQGPHR-HLERSWSSQEGGLG-PGGWWGCGEPSLGAAKAPEGAWGGTSREYKESWGQP 1491
            P +  P    L+ S S+       P      G  +  + K PE     T+ E + S    
Sbjct: 1199 PETVVPTALELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPV-VPTAPELQPSTSTD 1257

Query: 1492 EAWEEKPTHELPRELGKRSPLTSPPENWGGPAESSQSWHSGTPTAVGWGAEGACPYPRGS 1551
            +    +PT++  R    RS + +P        E   S  +  P           P P   
Sbjct: 1258 QPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVT---------PKPTSR 1308

Query: 1552 ERRPELDWRDLLGLLRAPGEGVWARVPSLDWEGLLELLQARLPRKDPAGHRDDLARALGP 1611
              R     R  +  ++ P E V    P L      +      P       R +++    P
Sbjct: 1309 TTRS----RTNMSSVKTP-ETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNP 1363

Query: 1612 ELGPPGTNDVPEQESHSQ---PEGWAEATPVNGHSPALQSQSPVQLPSPA-----CTSTQ 1663
            E   P   ++P   S  Q   PE  + AT   G       ++P  L   A      TST 
Sbjct: 1364 ESTVPIAPELPPSTSTEQPVTPEPTSRAT--RGRKNRSSGKTPETLVPTAPKLEPSTSTD 1421

Query: 1664 WPKIKVTRGPATATLAGLEQTGPLGSRSTAKGPSLPELQ-----FQPEEPE-ESEPSRGQ 1717
             P   VT  P +    G      + +  T   P+ PELQ      QP  PE  S+ +RG+
Sbjct: 1422 QP---VTPEPTSQATRGRTNRSSVKTPETVV-PTAPELQPSTSTDQPVTPEPTSQATRGR 1477

Query: 1718 DPLTDQKQADS 1728
               +  K  ++
Sbjct: 1478 TDRSSVKTPET 1488


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 286/1390 (20%), Positives = 456/1390 (32%), Gaps = 179/1390 (12%)

Query: 58   PAPEDPLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTAAPRSRSRELEAVPYLEG 117
            P+ +D   A  +   + V+P          + S G P   PT    +RS     V   E 
Sbjct: 781  PSSKDTRPAPPTTTSAFVEPS---------TTSHGSPSSIPTTHISARSTTSGLV---EE 828

Query: 118  LTTSLCGSCNEDPGSDPTSS-PDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPR 176
             TT      +  PGS  T   P+S T       S+    +       APS     V    
Sbjct: 829  STTY-----HSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALV---- 879

Query: 177  RPREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERH 236
               E P +  S    +  T  P     +G+ +E T             L   S  S+   
Sbjct: 880  ---EEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLG 936

Query: 237  RSTLTQASS--MTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASS 294
             ST +  SS  M   + P STT+    ++R T   +S R      SP   T    S  S+
Sbjct: 937  ESTTSPISSGSMETTALPGSTTTPGL-SERSTTFHSSPRSPATTLSPASTTSSGVSEEST 995

Query: 295  TQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNP 354
            T +  SR  ST       S+T     R S+T   +P ++ T       +    ST    P
Sbjct: 996  TSR--SRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDT-------TLLPASTTTSGP 1046

Query: 355  RTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKA 414
               ST   +   S  T                   A SP  TT     + S     NP +
Sbjct: 1047 SQESTTSHSSSGSTDT-------------------ALSPGSTTALSFGQESTTFHSNPGS 1087

Query: 415  SRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATR 474
            + T+    +T  +     + R +    SP        +TS   +    A +T   +  T 
Sbjct: 1088 THTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTT 1147

Query: 475  DNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRD 534
             +P  S A      +++  R+    PTT       P +S TS  +  +     +  A   
Sbjct: 1148 PSP-PSTATAPVEESTTYHRSPGSTPTTHF-----PASSTTSGHSEKSTIFHSSPDASGT 1201

Query: 535  NPRASSPNRAARDNPTTSCAQRDNPRASR-TSSPNRATRDN-PRTSCAQRDNPRASSPNR 592
             P ++    + R   TTS   R +P ++  T+ P   T       S     +PR  SP  
Sbjct: 1202 TPSSAHSTTSGRGESTTS---RISPGSTEITTLPGSTTTPGLSEASTTFYSSPR--SPTT 1256

Query: 593  ATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSC 652
                   TS    +    SR+   +  +  +P ++          S   TT   S R S 
Sbjct: 1257 TLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTP-----GLSEESTTVYSSSRGST 1311

Query: 653  ARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPN 712
                 P   S   ++  E P T      + R +S   T+  E+  TS    +        
Sbjct: 1312 ETTVFPH--STTTSVHGEEPTTF-----HSRPASTHTTLFTEDSTTSGLTEESTAFPGSP 1364

Query: 713  RTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSC 772
             +TQ   P           A+     +  ++     +        SP R+     +  S 
Sbjct: 1365 ASTQTGLP-----------ATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGEST 1413

Query: 773  TRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQD 832
              + +P ++            S +++     +SP       +P T     +   SST   
Sbjct: 1414 PSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHS 1473

Query: 833  NPKTSCTKR--DNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWN 890
             P ++ T    D+   +   ++ T S S Q     T S    T     + S+   S+  +
Sbjct: 1474 QPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGD 1533

Query: 891  NPRNSSPHRT-NKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQT 949
                  P  T    +  AS P   +      T +P+ S  + +   S   +        T
Sbjct: 1534 TETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTT 1593

Query: 950  SSP----SRPAQ-----HDPPQSSFGPTQYNLPSRAT---SSSHNPGHQSTSRTSSPVYP 997
             SP    + P +     H  P S+  PT +   S  T   S      H S   T + ++P
Sbjct: 1594 PSPPGTTAAPVEVSTTYHSRPSST--PTTHFSASSTTLGRSEESTTVHSSPGATGTALFP 1651

Query: 998  AAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESEPPHHEPP 1057
                  +   EP+  P +       A   S+    L      F+  PR+P++        
Sbjct: 1652 TRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTT------- 1704

Query: 1058 YIPPAVCIG---HRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCI 1114
             + PA         ++  + S P  T    FP          +  +    P      +  
Sbjct: 1705 -LSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTL-- 1761

Query: 1115 GYRDAPRASSPPRQAPEPSLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIG----HRD 1170
                +P +++     PE S  F   P ++  +L+P   +        TPV       H  
Sbjct: 1762 ----SPGSTTASSLGPE-STTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTT 1816

Query: 1171 APSFSSPPRQA--------PEPSLFFQDPPGTSMESLAPSTDSLHGSPVLIP-------Q 1215
                 S  RQ         P        PP T+   +  ST S HGSP   P        
Sbjct: 1817 LSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTS-HGSPSSTPTTHFSASS 1875

Query: 1216 VCIGHRD-------APRAS----SPPRHPPSDLA--FLAPSPSPGSS------GGSRGSA 1256
              +G  +       +P A+    SP R   S L     A   SPGS+        S  S 
Sbjct: 1876 TTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASG 1935

Query: 1257 PPGETRHNLEREEYTVLADLPPPRRLAQRQPGPQAQCSSGGRTHSPGRAEVERLFGQERR 1316
               E+R +     +T+ +   PP   +     P +  SS G T +    +     G   R
Sbjct: 1936 RSEESRTSHSSTTHTISS---PPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSG---R 1989

Query: 1317 KSEAAGAFQAQD-EGRSQQPSQGQSQLLRRQSSPAP----SRQVTMLPAKQAE--LTRRS 1369
              E+  +  +QD  G    P++  + +L  +S+ +P    S + T LP       L+ +S
Sbjct: 1990 SEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKS 2049

Query: 1370 QAEPPHPWSP 1379
                  P SP
Sbjct: 2050 TTFHSSPRSP 2059



 Score = 88.6 bits (218), Expect = 7e-17
 Identities = 294/1415 (20%), Positives = 475/1415 (33%), Gaps = 180/1415 (12%)

Query: 88   SPSAGLPEEGPTAAPRSRSRELEAVPYLEGLTTSLCGSCNEDPGSDPTSSPDSAT---PD 144
            S ++GL EE  TA P S +     +P    LTT+  G   E+  + P+SS  + T   P 
Sbjct: 2905 STTSGLTEES-TAFPGSPASTQTGLPAT--LTTADLG---EESTTFPSSSGSTGTTLSPA 2958

Query: 145  DTSNSSSVDWDTVERQEEEAPSWDEL--AVMIPRRPREGPRADSSQRAPSLLTRSPVGGD 202
             ++ S  V   T  R    +     L  +   P    +     +S R+P   T SP    
Sbjct: 2959 RSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA-TLSPATTT 3017

Query: 203  AAGQKKEDTGGGGRSAGQHWARLRGE---SGLSLERHRS---------TLTQASSMTPHS 250
            ++G  +E +    +    H          SGLS E   S         TL+  S+     
Sbjct: 3018 SSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSL 3077

Query: 251  GPRSTTSQASPAQRDTAQAAS---TREIPRASSPHRITQRDTSRASSTQQEISRASSTQQ 307
            G +STT  +SP   +T        T  +  AS+P        S   S    ++ ASST  
Sbjct: 3078 GQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTH------SSTGSLHTTLTPASSTSA 3131

Query: 308  ETSRASSTQEDTPRASSTQEDTPRAS------STQWNTPRASSPSR-----STQLDNPRT 356
                 S+T +  P +S T    P  +      ST +++  +S+P+      ST L     
Sbjct: 3132 GLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEE 3191

Query: 357  SSTQQDNPQTSFPTCTPQR--------ENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQ 408
            S+T   +P  +     P R        E   +P         + P  TT    S  S   
Sbjct: 3192 STTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTF 3251

Query: 409  RDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSS 468
              +P++  T+    +T  +  +  +   + R  S         TT         AS +S 
Sbjct: 3252 YSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSP 3311

Query: 469  PNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRAS---RTSSPNRATRDN 525
             +  T  +P ++ A    P +++         TT     DN  AS     S+P  ++  +
Sbjct: 3312 GSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLP--DNTTASGLLEASTPVHSSTGS 3369

Query: 526  PRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNP 585
            P T+ +    P  S+     R   +T+     N + + T +P   T      S     +P
Sbjct: 3370 PHTTLS----PAGST----TRQGESTTFQSWPNSKDT-TPAPPTTTSAFVELSTTSHGSP 3420

Query: 586  RAS-----SPNRATRDNPTTSCAQRDNPRASRTS-SPNRATRDNPRTSCAQRDNPRASSP 639
             ++     S +  T      S     +P A+ T+ SP R+T     +   +      SSP
Sbjct: 3421 SSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTT----SGLVEESTTYHSSP 3476

Query: 640  NRTTQQDSPR--TSCARRDDPRAS--SPNRTIQQENPRTSCALRDNPRA--SSPSRTIQQ 693
              T     P   T+  R ++   S  S   TI    P T+ AL + P +  SSP  T   
Sbjct: 3477 GSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSA-PSTTSALVEEPTSYHSSPGSTATT 3535

Query: 694  ENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDN 753
              P +S        +++ + +          AR       S    +  ++  +  +    
Sbjct: 3536 HFPDSSTTSGRSEESTASHSSQDATGTIVLPAR-------STTSVLLGESTTSPISSGSM 3588

Query: 754  PRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQD 813
               + P  T        S T   +PR+ +   +      +  ++      S P       
Sbjct: 3589 ETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTA 3648

Query: 814  NPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCT 873
             P +     + R S+T   +P ++ T    L P  T    T S S Q      SSS    
Sbjct: 3649 FPDSTTTPGLSRHSTTSHSSPGSTDT---TLLPAST----TTSGSSQESTTSHSSSGSTD 3701

Query: 874  QKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSD----GPRTSSPSRSKQ 929
               +   ++     Q +   +SSP  T+  +    FP   T S       R  S + S +
Sbjct: 3702 TALSPGSTTALSFGQESTTFHSSPGSTHTTL----FPDSTTSSGIVEASTRVHSSTGSPR 3757

Query: 930  SEVPWASIALRPTQGDRP--QTSSPSRPAQHDPPQSSFGP----TQYNLPSRATSSSHNP 983
            + +  AS      QG+    QT   S      PP ++  P    T Y+    +T ++H P
Sbjct: 3758 TTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFP 3817

Query: 984  GHQSTSRTS--SPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFP-- 1039
               +TS  S  S ++ ++  A  T+P  +    +   G  ++  +   P   +    P  
Sbjct: 3818 ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTS---GRGESTTSRISPGSTEITTLPGS 3874

Query: 1040 ------------FFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSP-PRHTQFDPF- 1085
                        F+  PR+P +       P    ++ +G       S P   H+   P  
Sbjct: 3875 TTTPGLSEASTTFYSSPRSPTTTLS----PASMTSLGVGEESTTSRSQPGSTHSTVSPAS 3930

Query: 1086 ---PFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQD---- 1138
               P L + S   +       E    P       R     +   R A   + LF +    
Sbjct: 3931 TTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTT 3990

Query: 1139 --LPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSM 1196
              L   ST        +    P   T   +G       SS      + S       G   
Sbjct: 3991 SGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVG 4050

Query: 1197 ES----LAPS---TDSLHGSPVLIPQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGSS 1249
            ES    L+PS   T +L GSP   P +      +    + PR P + L+    + S  S 
Sbjct: 4051 ESTPSRLSPSSTETTTLPGSPTT-PSLS---EKSTTFYTSPRSPDATLSPATTTSSGVSE 4106

Query: 1250 GGSRGSAPPGETRHNLEREEYTVLADLPPPRRLAQRQPGPQAQCSSGGRTHSPGRAEVER 1309
              S   + PG T         T   D      L+Q      +   S   T SPG      
Sbjct: 4107 ESSTSHSQPGST-------HTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASS 4159

Query: 1310 LFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPSR----QVTMLPAKQAEL 1365
            L  Q      + G     D   +  P    +  L   S+P  S       T+ PA     
Sbjct: 4160 LGQQSTTFHSSPG-----DTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTST 4214

Query: 1366 TRRSQAEPPHPWSPEKRPEGDRQLQGSPLPPRTSA 1400
              + ++     W              +P PP T+A
Sbjct: 4215 GLQEESTTFQSWPSSS--------DTTPSPPSTTA 4241



 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 272/1243 (21%), Positives = 420/1243 (33%), Gaps = 164/1243 (13%)

Query: 44   SGAEVPYCDLPRCPPAPEDPLSASTSGC-QSVVDPGLRPGPKRGP-SPSA----GLPEEG 97
            S A   +   PR P     P S ++ G  +       +PG      SP++    GL EE 
Sbjct: 1241 SEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEES 1300

Query: 98   PTAAPRSRSRELEAVPYLEGLTTSLCGSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTV 157
             T    SR    E   +    TTS+ G       S P S+  +   +D++ S   +  T 
Sbjct: 1301 TTVYSSSRG-STETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTA 1359

Query: 158  ERQEEEAPSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAG--QKKEDTGGGG 215
                             P  P     A +    P+ LT + +G ++         TG   
Sbjct: 1360 ----------------FPGSP-----ASTQTGLPATLTTADLGEESTTFPSSSGSTGTKL 1398

Query: 216  RSAGQHWARLRGESG---LSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAAST 272
              A    + L GES    LS     +T    S  TP    +STT   SP   D       
Sbjct: 1399 SPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA------ 1452

Query: 273  REIPRASSPHRITQRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRA 332
                   SP   T    S  SST       S +Q  ++  ++  + T  +  +QE T  +
Sbjct: 1453 -----TLSPATTTSSGVSEESST-------SHSQPGSTHTTAFPDSTTTSDLSQEPT-TS 1499

Query: 333  SSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASS 392
             S+Q +T    SP  +T     + S+T   +P  +  T  P  +   +  V+   P  SS
Sbjct: 1500 HSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPD-DTITSGLVEASTPTHSS 1558

Query: 393  PN--RTTQRENSRTSCAQRDN-------PKASRTS-SPNRATRDNPRTSCAQRDNPRAS- 441
                 TT    S TS   ++        P +S T+ SP   T      S      P ++ 
Sbjct: 1559 TGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTP 1618

Query: 442  ----SPSRATRDNPTTSCAQRDNPRASRTS-SPNRATRD----NPRTSCAQRDNPRASS- 491
                S S  T      S     +P A+ T+  P R+        P TS     +   ++ 
Sbjct: 1619 TTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTAL 1678

Query: 492  -PSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPT 550
              S  T      S     +PR+  T+    +T  +  +  +   + R  S +  A    T
Sbjct: 1679 PGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGST 1738

Query: 551  TSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRA----SSPNRATR----DNPTTS- 601
            T         AS +S  +  T  +P ++ A    P +    SSP         DN T S 
Sbjct: 1739 TMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASG 1798

Query: 602  CAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCA---RRDDP 658
              +   P  S T SP+        T+         S P+      +P T+ +        
Sbjct: 1799 LLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTT 1858

Query: 659  RASSPNRTIQQENPRTSCALRDNPRA----SSPSRTIQQENPRTS----CAQRDDPRASS 710
               SP+ T       +S  L  +  +    SSP  T    +P  S      +      SS
Sbjct: 1859 SHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSS 1918

Query: 711  PNRTTQQENPRTSCA--RRDNPRA--SSRNRTIQRDNPRTSCAQRDNPRA--SSPNRTIQ 764
            P  T     P +S A  R +  R   SS   TI    P T+ A  + P +  SSP  T  
Sbjct: 1919 PGSTQTMHFPESSTASGRSEESRTSHSSTTHTIS-SPPSTTSALVEEPTSYHSSPGST-A 1976

Query: 765  QENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIP 824
              +   S T       S+ + +++D   T            P R+T      T +     
Sbjct: 1977 TTHFPDSSTTSGRSEESTASHSSQDATGTIVL---------PARST------TSVLLGES 2021

Query: 825  RSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPH 884
             +S     + +T+        P  +++  T  F     +P T+ S   T    +   S  
Sbjct: 2022 TTSPISSGSMETTALPGSTTTPGLSEKSTT--FHSSPRSPATTLSPASTTSSGVSEES-- 2077

Query: 885  RSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQG 944
                 ++ R  S H T       +FP   T     R S+ S S         +    T  
Sbjct: 2078 ---TTSHSRPGSTHTT-------AFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS 2127

Query: 945  DRPQ--TSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQST-----SRTSSPVYP 997
               Q  T+S S P   D   S    T  +    +T+   +PG   T     S TSS +  
Sbjct: 2128 GPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVE 2187

Query: 998  A------AYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESEP 1051
            A      + G+P T+  P+        G   A    + P      P P        E   
Sbjct: 2188 ASTRVHSSTGSPRTTLSPASSTSPGLQGESTA--FQTHPASTHTTPSPPSTATAPVEEST 2245

Query: 1052 PHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDP-FPFLPD----TSDAEHQCQSPQHE-P 1105
             +H  P   P         P +S+   H++    F   PD    T  + H   S + E  
Sbjct: 2246 TYHRSPGSTPTT-----HFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGEST 2300

Query: 1106 LQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQDLPRASTESLVP-SMDSLHECPHIPT-- 1162
                +P        P +++ P  + E S  F   PR+ T +L P SM SL       T  
Sbjct: 2301 TSRISPGSTEITTLPGSTTTPGLS-EASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSR 2359

Query: 1163 --PVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLAPST 1203
              P       +P+ ++ P  + E +  +   PG++  ++ P T
Sbjct: 2360 SQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRT 2402



 Score = 79.0 bits (193), Expect = 5e-14
 Identities = 249/1184 (21%), Positives = 409/1184 (34%), Gaps = 155/1184 (13%)

Query: 186  SSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGES---GLSLERHRS---- 238
            SS R+P   T SP    ++G  +E T    R    H     G +   G+S E   S    
Sbjct: 3253 SSPRSPDT-TLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSP 3311

Query: 239  -----TLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRAS 293
                 TL+  S+     GP STT  + P   +T        +P  ++   + +  T   S
Sbjct: 3312 GSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTL------LPDNTTASGLLEASTPVHS 3365

Query: 294  STQQEISRASSTQQETSRASST--------QEDTPRASSTQEDTPRASSTQWNTPRASSP 345
            ST    +  S     T +  ST        ++ TP   +T       S+T   +P ++  
Sbjct: 3366 STGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPT 3425

Query: 346  SR----STQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRT-TQRE 400
            +     ST L     S+T   +P  +  T +P R    +  V++     SSP  T T   
Sbjct: 3426 THFSASSTTLGRSEESTTVHSSPVATATTPSPARSTT-SGLVEESTTYHSSPGSTQTMHF 3484

Query: 401  NSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRA--SSP-SRATRDNP--TTSC 455
                + + R     +  SS        P T+ A  + P +  SSP S AT   P  +T+ 
Sbjct: 3485 PESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTS 3544

Query: 456  AQRDNPRASRTSSPNRATRDNP-RTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASR 514
             + +   AS +S     T   P R++ +       +SP  +     T        P  S 
Sbjct: 3545 GRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSE 3604

Query: 515  TSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSS-PNRATRD 573
             S+   ++  +P T+ +      AS+ +    +  TTS      P ++ T++ P+  T  
Sbjct: 3605 KSTTFHSSPRSPATTLSP-----ASTTSSGVSEESTTS---HSRPGSTHTTAFPDSTTTP 3656

Query: 574  N-PRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRD 632
               R S     +P ++          T+  +Q      S TS  +  + D          
Sbjct: 3657 GLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQE-----STTSHSSSGSTDT--------- 3702

Query: 633  NPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQ 692
               A SP  TT     + S      P   S + T+  ++  +S  +  + R  S + +  
Sbjct: 3703 ---ALSPGSTTALSFGQESTTFHSSP--GSTHTTLFPDSTTSSGIVEASTRVHSSTGS-- 3755

Query: 693  QENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRD 752
               PRT+ +      ASS +   Q E    S A + +P  +S + T    +  T+  +  
Sbjct: 3756 ---PRTTLSP-----ASSTSPGLQGE----STAFQTHP--ASTHTTPSPPSTATAPVEES 3801

Query: 753  NPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQ 812
                 SP  T    +   S T   +   S+   ++ D   T+ +   +  +      T +
Sbjct: 3802 TTYHRSPGST-PTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSR 3860

Query: 813  DNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCC 872
             +P +     +P S++T   +  ++        PT T    + +     +   TS SQ  
Sbjct: 3861 ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG 3920

Query: 873  TQKENLRPSS---PHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQ 929
            +    + P+S   P  S +     +SSP  T   +    FP   T S      +   S+ 
Sbjct: 3921 STHSTVSPASTTTPGLSEESTTVYSSSPGSTETTV----FPRSTTTSVRREEPTTFHSRP 3976

Query: 930  SEVPWASIALRPTQGDRPQTSS--PSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQS 987
            +           T     + S+  P  PA           TQ  LP  AT ++ + G +S
Sbjct: 3977 ASTHTTLFTEDSTTSGLTEESTAFPGSPAS----------TQTGLP--ATLTTADLGEES 4024

Query: 988  TSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPE-PRA 1046
            T+      +P++ G+  T   P++   +  +G     R S  P   +    P  P  P  
Sbjct: 4025 TT------FPSSSGSTGTKLSPARSTTSGLVGESTPSRLS--PSSTETTTLPGSPTTPSL 4076

Query: 1047 PESEPPHHEPPYIPPAVCIG--------HRDAPRASSPPRHTQFDPFPFLPDTSD----- 1093
             E     +  P  P A              ++  + S P  T    FP    TS      
Sbjct: 4077 SEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEP 4136

Query: 1094 -AEHQCQSPQHEPLQLPAPVC--IGYRDAPRASSPPRQAPEPSLLFQD-LPRASTESLVP 1149
               H  Q      L   +     +G +     SSP     E +LL  D +     E+  P
Sbjct: 4137 TTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDT--ETTLLPDDTITSGLVEASTP 4194

Query: 1150 SMDSLHECPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLAPSTDSLHGS 1209
            +  S        TP           S+  +  P  S     PP T+   +  ST + H  
Sbjct: 4195 THSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVST-TYHSR 4253

Query: 1210 PVLIP-------QVCIGHRDAPRA--SSP--------PRHPPSDLAFLAPSPSPGSSGGS 1252
            P   P          +G  +      SSP        P    + +    P+ SP SSG +
Sbjct: 4254 PSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGST 4313

Query: 1253 RGSAPPGETRHNLEREEYTVLADLPPPRRLAQRQPGPQAQCSSG 1296
              +A PG T      E+ T     P   R       P +  SSG
Sbjct: 4314 ETTALPGSTTTAGLSEKSTTFYSSP---RSPDTTLSPASTTSSG 4354



 Score = 77.8 bits (190), Expect = 1e-13
 Identities = 279/1346 (20%), Positives = 456/1346 (33%), Gaps = 159/1346 (11%)

Query: 63   PLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTAAPRSRSRELEAVPYLEGLTTSL 122
            P  +ST    + + P          S SAGL EE  T   +S     +  P   G T + 
Sbjct: 1554 PTHSSTGSLHTTLTPA--------SSTSAGLQEESTTF--QSWPSSSDTTPSPPGTTAAP 1603

Query: 123  CGSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGP 182
                     S    S  S+TP    ++SS    T+ R EE                  G 
Sbjct: 1604 VEV------STTYHSRPSSTPTTHFSASST---TLGRSEESTTVHSSPGAT-------GT 1647

Query: 183  RADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRSTLTQ 242
                ++ A S+L   P     +    E T   G +     +        S     +TL+ 
Sbjct: 1648 ALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSP 1707

Query: 243  ASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEISRA 302
            AS+ +      STTS + P    T     +  +P  S     +    S   ST   +S  
Sbjct: 1708 ASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASH---SSPGSTDTTLSPG 1764

Query: 303  SSTQQETSRASSTQEDTPRASST---QEDTPRASSTQWNTPRASSPSRSTQLDNPRTSST 359
            S+T       S+T   +P ++ T    ++T  +   + +TP  SS        +P  S+T
Sbjct: 1765 STTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTT 1824

Query: 360  QQDNPQT--SFPTCTPQRENPRTPC---VQQDDPRASSPNR--TTQRENSRTSCAQRDNP 412
            +Q    T  S+P+       P T     V+       SP+   TT    S T+  + +  
Sbjct: 1825 RQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEES 1884

Query: 413  KASRTSSPNRATRDNPRTS----CAQRDNPRASSP-SRATRDNPTTSCAQ-RDNPRASRT 466
                +S    AT  +P  S      +      SSP S  T   P +S A  R     +  
Sbjct: 1885 TTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSH 1944

Query: 467  SSPNRATRDNPRTSCAQRDNPRA--SSP-SRATRDNP--TTSCAQRDNPRASRTSSPNRA 521
            SS        P T+ A  + P +  SSP S AT   P  +T+  + +   AS +S     
Sbjct: 1945 SSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATG 2004

Query: 522  TRDNP-RTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCA 580
            T   P R++ +       +SP  +     T        P  S  S+   ++  +P T+ +
Sbjct: 2005 TIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLS 2064

Query: 581  QRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSS-PNRATRDN-PRTSCAQRDNPRASS 638
                  AS+ +    +  TTS      P ++ T++ P+  T     R S     +P ++ 
Sbjct: 2065 P-----ASTTSSGVSEESTTS---HSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTD 2116

Query: 639  ----PNRTTQQDSPRTSCARRDDP----RASSPNRTIQQENPRTSCALRDNPRA------ 684
                P  TT     + S      P     A SP  T      + S     +P +      
Sbjct: 2117 TTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLF 2176

Query: 685  --SSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRD 742
              S+ S  I + + R   +        SP  +T       S A + +P  +S + T    
Sbjct: 2177 PDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHP--ASTHTTPSPP 2234

Query: 743  NPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLR 802
            +  T+  +       SP  T    +   S T   +   S+   ++ D   T+ +   +  
Sbjct: 2235 STATAPVEESTTYHRSPGST-PTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTT 2293

Query: 803  ASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRD 862
            +      T + +P +     +P S++T   +  ++        PT T    + +     +
Sbjct: 2294 SGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGE 2353

Query: 863  NPGTSSSQCCTQKENLRPSS---PHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGP 919
               TS SQ  +    + P+S   P  S +     +SSP  T   +    FP  PT S   
Sbjct: 2354 ESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTV----FPRTPTTSVRG 2409

Query: 920  RTSSPSRSKQSEVPWASIALRPTQG--DRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRAT 977
               +   S+ +           T        T+ P  PA           TQ  LP  AT
Sbjct: 2410 EEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPAS----------TQTGLP--AT 2457

Query: 978  SSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDP 1037
             ++ + G +ST+      +P++ G+  T+  P++   +  +G     R S  P   +   
Sbjct: 2458 LTTADLGEESTT------FPSSSGSTGTTLSPARSTTSGLVGESTPSRLS--PSSTETTT 2509

Query: 1038 FPFFP-EPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEH 1096
             P  P  P   E     +  P  P A            SP   T       + + S   H
Sbjct: 2510 LPGSPTTPSLSEKSTTFYTSPRSPDATL----------SPATTTSSG----VSEESSTSH 2555

Query: 1097 QCQSPQHEPLQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQDLPRASTESLVPSMDSL-- 1154
                  H      +    G       S     + + +LL      AST +  PS +S   
Sbjct: 2556 SQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLL-----PASTTTSGPSQESTTS 2610

Query: 1155 HECP-HIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLAPSTDSLHGSPVLI 1213
            H  P    T +  G   A SF        + S  F   PG++  +L P + +  G     
Sbjct: 2611 HSSPGSTDTALSPGSTTALSFG-------QESTTFHSSPGSTHTTLFPDSTTSSGIVEAS 2663

Query: 1214 PQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVL 1273
             +V      +PR +  P          A S SPG  G S        + H       T  
Sbjct: 2664 TRV-HSSTGSPRTTLSP----------ASSTSPGLQGESTTFQTHPASTHTTPSPPSTAT 2712

Query: 1274 ADLPPPRRLAQRQPGPQAQCSSGGRTHSPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQ 1333
            A +        R PG          + + G +E   +F       +A+G   +     + 
Sbjct: 2713 APVEESTTY-HRSPGSTPTTHFPASSTTSGHSEKSTIF---HSSPDASGTTPSS----AH 2764

Query: 1334 QPSQGQSQLLRRQSSPAPSRQVTMLP 1359
              + G+ +    + SP  S ++T LP
Sbjct: 2765 STTSGRGESTTSRISPG-STEITTLP 2789



 Score = 77.4 bits (189), Expect = 2e-13
 Identities = 237/1109 (21%), Positives = 380/1109 (34%), Gaps = 153/1109 (13%)

Query: 186  SSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGES---GLSLERHRS---- 238
            SS R+P   T SP    ++G  ++ T    R    H       +   G+S E   S    
Sbjct: 285  SSPRSPDR-TLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIP 343

Query: 239  ----TLTQASSMTPHS-GPRSTTSQASPAQRDTAQA---ASTREIPRASSPHRITQRDTS 290
                T     + TP S GP STT  +SP    T +     +T  +  AS+P        S
Sbjct: 344  GSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVH------S 397

Query: 291  RASSTQQEISRASSTQQETSRAS-----STQEDTPRASSTQEDTPRASSTQWNTPRASSP 345
               S    +S +SST  E    +     S+++ +P  S T     + S+T  ++P +S+P
Sbjct: 398  STGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSP-SSTP 456

Query: 346  SRSTQLDNPRTSSTQQDNPQTSFPTCT----PQRENPRTPCVQQDDPRASSPNRT-TQRE 400
            +      +     +++  P  S P  T    P   +  +  V++      SP  T T   
Sbjct: 457  TTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHF 516

Query: 401  NSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDN 460
               ++ +      A+   S        P T+ A       SS         T +   RD+
Sbjct: 517  PESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSL------GSTETTHFRDS 570

Query: 461  PRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRD---NPTTSCAQRDNPRASRTSS 517
               S  S  ++A+  +P  + A    P  S+PS    D   +P +S +         T+ 
Sbjct: 571  STISGRSEESKASHSSP-DAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTK 629

Query: 518  PNRATR-----DNPR----------------TSCAQRDNPRASSPNRAARDNPTTSCAQR 556
            P  + +      +PR                +  +   + R  S +  A    TT     
Sbjct: 630  PGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLS 689

Query: 557  DNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRAS---RT 613
                AS +S     T  +P ++ A    P  ++ +  +R   T +    DN  AS     
Sbjct: 690  QESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFH--SRPGSTETTLLPDNTTASGLLEA 747

Query: 614  SSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRT--SCARRDDPRASSPNRTIQQEN 671
            S P  ++  +P T+         S    TT+Q    T  S     D R + P  T     
Sbjct: 748  SMPVHSSTRSPHTT--------LSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVE 799

Query: 672  PRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPR--TSCARRDN 729
            P T+        +S P+  I   +  +   +      SSP  T     P   T+  R + 
Sbjct: 800  PSTT---SHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEE 856

Query: 730  PRA--SSRNRTIQRDNPRTSCAQRDNPRA--SSPNRTIQQENLRTSCTRQDNPRTSSPNR 785
                 SS   TI    P T+ A  + P +  SSP  T    +   S T       S+ + 
Sbjct: 857  STTSHSSTTHTIS-SAPSTTSALVEEPTSYHSSPGST-ATTHFPDSSTTSGRSEESTASH 914

Query: 786  ATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLR 845
            +++D   T            P R+T      T +      +S     + +T+        
Sbjct: 915  SSQDATGTIVL---------PARST------TSVLLGESTTSPISSGSMETTALPGSTTT 959

Query: 846  PTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIP 905
            P  ++R  T  F     +P T+ S   T    +   S       +  R  S H T     
Sbjct: 960  PGLSERSTT--FHSSPRSPATTLSPASTTSSGVSEES-----TTSRSRPGSTHTT----- 1007

Query: 906  WASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQ--TSSPSRPAQHDPPQS 963
              +FP   T     R S+ S S         +    T     Q  T+S S     D   S
Sbjct: 1008 --AFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALS 1065

Query: 964  SFGPTQYNLPSRATSSSHNPGHQST-----SRTSSPVYPA------AYGAPLTSPEPSQP 1012
                T  +    +T+   NPG   T     S TSS +  A      + G+P T+  P+  
Sbjct: 1066 PGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASS 1125

Query: 1013 PCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPR 1072
                  G   A    + P      P P        E    +H  P   P         P 
Sbjct: 1126 TSPGLQGESTA--FQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTT-----HFPA 1178

Query: 1073 ASSPPRHTQFDP-FPFLPD----TSDAEHQCQSPQHE-PLQLPAPVCIGYRDAPRASSPP 1126
            +S+   H++    F   PD    T  + H   S + E      +P        P +++ P
Sbjct: 1179 SSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTP 1238

Query: 1127 RQAPEPSLLFQDLPRASTESLVP-SMDSLHECPHIPT----PVCIGHRDAPSFSSPPRQA 1181
              + E S  F   PR+ T +L P SM SL       T    P       +P+ ++ P  +
Sbjct: 1239 GLS-EASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLS 1297

Query: 1182 PEPSLFFQDPPGTSMESLAP--STDSLHG 1208
             E +  +    G++  ++ P  +T S+HG
Sbjct: 1298 EESTTVYSSSRGSTETTVFPHSTTTSVHG 1326



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 266/1241 (21%), Positives = 414/1241 (33%), Gaps = 164/1241 (13%)

Query: 44   SGAEVPYCDLPRCPPAPEDPLSASTSGC-QSVVDPGLRPGPKRGP-SPSA----GLPEEG 97
            S A   +   PR P     P S ++ G  +       +PG      SP++    GL EE 
Sbjct: 2798 SEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEES 2857

Query: 98   PTAAPRSRSRELEAVPYLEGLTTSLCGSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTV 157
             T    S     E   +    TTS+ G       S P S+  +   +D++ S   +  T 
Sbjct: 2858 TTVYSSSPG-STETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTA 2916

Query: 158  ERQEEEAPSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAG--QKKEDTGGGG 215
                             P  P     A +    P+ LT + +G ++         TG   
Sbjct: 2917 ----------------FPGSP-----ASTQTGLPATLTTADLGEESTTFPSSSGSTGTTL 2955

Query: 216  RSAGQHWARLRGESG---LSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAAST 272
              A    + L GES    LS     +T    S  TP    +STT   SP   D       
Sbjct: 2956 SPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA------ 3009

Query: 273  REIPRASSPHRITQRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRA 332
                   SP   T    S  SST       S +Q  ++  ++  + T  +  +QE T  +
Sbjct: 3010 -----TLSPATTTSSGVSEESST-------SHSQPGSTHTTAFPDSTTTSGLSQEPT-AS 3056

Query: 333  SSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASS 392
             S+Q +T    SP  +T     + S+T   +P  +  T  P  +   +  V+   P  SS
Sbjct: 3057 HSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPD-DTITSGLVEASTPTHSS 3115

Query: 393  PN--RTTQRENSRTSCAQRDN-------PKASRTS-SPNRATRDNPRTSCAQRDNPRAS- 441
                 TT    S TS   ++        P +S T+ SP   T      S      P ++ 
Sbjct: 3116 TGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTP 3175

Query: 442  ----SPSRATRDNPTTSCAQRDNPRASRTS-SPNRATRD----NPRTSCAQRDNPRASS- 491
                S S  T      S     +P A+ T+  P R+        P TS     +   ++ 
Sbjct: 3176 TTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTAL 3235

Query: 492  -PSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPT 550
              S  T      S     +PR+  T+    +T  +  +  +   + R  S +  A    T
Sbjct: 3236 PGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGST 3295

Query: 551  TSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRA--------SSPNRATRDNPTTS- 601
            T         AS +S  +  T  +P ++ A    P +        S+      DN T S 
Sbjct: 3296 TMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASG 3355

Query: 602  CAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCA---RRDDP 658
              +   P  S T SP+        T+         S PN      +P T+ +        
Sbjct: 3356 LLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTT 3415

Query: 659  RASSPNRTIQQENPRTSCALRDNPRA----SSPSRTIQQENPRTS----CAQRDDPRASS 710
               SP+ T       +S  L  +  +    SSP  T    +P  S      +      SS
Sbjct: 3416 SHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSS 3475

Query: 711  PNRTTQQENPR--TSCARRDNPRA--SSRNRTIQRDNPRTSCAQRDNPRA--SSPNRTIQ 764
            P  T     P   T+  R +      SS   TI    P T+ A  + P +  SSP  T  
Sbjct: 3476 PGSTQTMHFPESDTTSGRGEESTTSHSSTTHTIS-SAPSTTSALVEEPTSYHSSPGST-A 3533

Query: 765  QENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIP 824
              +   S T       S+ + +++D   T            P R+T      T +     
Sbjct: 3534 TTHFPDSSTTSGRSEESTASHSSQDATGTIVL---------PARST------TSVLLGES 3578

Query: 825  RSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPH 884
             +S     + +T+        P  +++  T  F     +P T+ S   T    +   S  
Sbjct: 3579 TTSPISSGSMETTALPGSTTTPGLSEKSTT--FHSSPRSPATTLSPASTTSSGVSEES-- 3634

Query: 885  RSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQG 944
                 ++ R  S H T       +FP   T     R S+ S S         +    T  
Sbjct: 3635 ---TTSHSRPGSTHTT-------AFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS 3684

Query: 945  DRPQ--TSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQST-----SRTSSPVYP 997
               Q  T+S S     D   S    T  +    +T+   +PG   T     S TSS +  
Sbjct: 3685 GSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVE 3744

Query: 998  A------AYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESEP 1051
            A      + G+P T+  P+        G   A    + P      P P        E   
Sbjct: 3745 ASTRVHSSTGSPRTTLSPASSTSPGLQGESTA--FQTHPASTHTTPSPPSTATAPVEEST 3802

Query: 1052 PHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDP-FPFLPD----TSDAEHQCQSPQHE-P 1105
             +H  P   P         P +S+   H++    F   PD    T  + H   S + E  
Sbjct: 3803 TYHRSPGSTPTT-----HFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGEST 3857

Query: 1106 LQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQDLPRASTESLVP-SMDSLHECPHIPT-- 1162
                +P        P +++ P  + E S  F   PR+ T +L P SM SL       T  
Sbjct: 3858 TSRISPGSTEITTLPGSTTTPGLS-EASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSR 3916

Query: 1163 --PVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLAP 1201
              P       +P+ ++ P  + E +  +   PG++  ++ P
Sbjct: 3917 SQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFP 3957



 Score = 71.6 bits (174), Expect = 8e-12
 Identities = 206/984 (20%), Positives = 343/984 (34%), Gaps = 114/984 (11%)

Query: 63   PLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTAAP-RSRSRELEAVPYLEGLTTS 121
            P  +ST    + + P          S S GL EE  T     S S    + P    +   
Sbjct: 4194 PTHSSTGSLHTTLTPA--------SSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVE 4245

Query: 122  LCGSCNEDPGSDPTS--SPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPR 179
            +  + +  P S PT+  S  S T   +  S++V            P+    +V++   P 
Sbjct: 4246 VSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE-PT 4304

Query: 180  EGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRST 239
              P +  S    +L    P     AG  ++ T          ++  R           +T
Sbjct: 4305 TSPISSGSTETTAL----PGSTTTAGLSEKST--------TFYSSPRSPD--------TT 4344

Query: 240  LTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEI 299
            L+ AS+ +      STTS + P    T    S+  +P  S     +    S   ST   +
Sbjct: 4345 LSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASH---SSPGSTDTTL 4401

Query: 300  SRASSTQQETSRASSTQEDTPRASST---QEDTPRASSTQWNTPRASSPSRSTQLDNPRT 356
            S  S+T       S+T   +P ++ T    ++T  +   + +TP  SS        +P  
Sbjct: 4402 SPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAG 4461

Query: 357  SSTQQDNPQT--SFPT---CTPQRENPRTPCVQQDDPRASSPNRT---------TQRENS 402
            S+T+Q    T  S+P     TP      +  V+       SP+ T         T    S
Sbjct: 4462 STTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRS 4521

Query: 403  RTSCAQRDNPKASRTS-SPNRATRDN-PRTSCAQRDNPRASSPSRATRDNPTTSCAQRDN 460
              S     +P A+ T+ SP R+T       S     +P ++        N T+    R  
Sbjct: 4522 EESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSG---RGE 4578

Query: 461  PRASRTSSPNRATRDNPRTSCAQRDNPRA--SSP-SRATRDNP--TTSCAQRDNPRASRT 515
               +  SS        P T+ A  + P +  SSP S AT   P  +T+  + +   AS +
Sbjct: 4579 ESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHS 4638

Query: 516  SSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNP 575
            S     T   P  S         S     +  +P +S +         T++P  + +   
Sbjct: 4639 SQDATGTIVLPARS-------TTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTT 4691

Query: 576  RTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTS-SPNRATRDNPRTSCAQRDNP 634
              S          S +  T      S     +P A+ T+ SP R+T     +   +    
Sbjct: 4692 FHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARST----TSGLVEESTA 4747

Query: 635  RASSPNRTTQQDSPRTSCA--RRDDPRA--SSPNRTIQQENPRTSCALRDNPRA--SSPS 688
              SSP  T     P +S A  R ++ R   SS   TI    P T+ AL + P +  SSP 
Sbjct: 4748 YHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSP-PSTTSALVEEPTSYHSSPG 4806

Query: 689  RTIQQENPR--TSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRT 746
                   P   T+  + ++  AS  +  T    P  +        A S    I   +  T
Sbjct: 4807 SIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMET 4866

Query: 747  SCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDN----PRTSCAQRDNLR 802
            + A      A++P  + +   L +S    D  +T SP   T  +    P +  +Q ++  
Sbjct: 4867 TLAS----TATTPGLSAKSTILYSSSRSPD--QTLSPASMTSSSISGEPTSLYSQAESTH 4920

Query: 803  ASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRP-TCTQRDRTQSFSFQR 861
             ++         P +     + + S+T    P ++ T    L P + T     Q F+   
Sbjct: 4921 TTA--------FPASTTTSGLSQESTTFHSKPGSTET---TLSPGSITTSSFAQEFTTPH 4969

Query: 862  DNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSS----PHRTNKDIPWASFPLRPTQSD 917
              PG++ S        +   S   +T +++P ++      H     I        P    
Sbjct: 4970 SQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPG 5029

Query: 918  GPRTSSPSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHD----PPQSSFGPT-QYNL 972
               T  P+    +++   S A   +      T  P+R    D    P      P+  Y  
Sbjct: 5030 FTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDLVGEPTTFYISPSPTYTT 5089

Query: 973  PSRATSSSHNPGHQSTSRTSSPVY 996
               A+SS+     +ST+  +SP +
Sbjct: 5090 LFPASSSTSGLTEESTTFHTSPSF 5113



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 290/1404 (20%), Positives = 445/1404 (31%), Gaps = 214/1404 (15%)

Query: 5    PGDALCEHFEANILTQNRCQNC--FH---------PEEAH------GARYQELRSPSGAE 47
            PG     HF A+  T    +    FH         P  AH      G       SP   E
Sbjct: 3808 PGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTE 3867

Query: 48   VPYCDLPRCPPAPEDPLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTAAPRSRSR 107
            +    LP     P     AST+   S   P     P      S G+ EE  T+  +  S 
Sbjct: 3868 IT--TLPGSTTTP-GLSEASTTFYSSPRSPTTTLSP--ASMTSLGVGEESTTSRSQPGST 3922

Query: 108  ELEAVPY---LEGLTTSLCGSCNEDPGSDPTSS-PDSAT-------PDDTSNSSSVDWDT 156
                 P      GL+       +  PGS  T+  P S T       P    +  +    T
Sbjct: 3923 HSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTT 3982

Query: 157  VERQEEEAPSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAG--QKKEDTGGG 214
            +  ++       E +   P  P     A +    P+ LT + +G ++         TG  
Sbjct: 3983 LFTEDSTTSGLTEESTAFPGSP-----ASTQTGLPATLTTADLGEESTTFPSSSGSTGTK 4037

Query: 215  GRSAGQHWARLRGESG---LSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAAS 271
               A    + L GES    LS     +T    S  TP    +STT   SP   D   + +
Sbjct: 4038 LSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPA 4097

Query: 272  ----------------------TREIPRASSPHRITQRDT---SRASSTQQEISRASSTQ 306
                                  T   P +++   ++Q  T   S   ST+  +S  S+T 
Sbjct: 4098 TTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTA 4157

Query: 307  QETSRASSTQEDTPRASST---QEDTPRASSTQWNTPRASS---------PSRSTQLDNP 354
                + S+T   +P  + T    +DT  +   + +TP  SS         P+ ST     
Sbjct: 4158 SSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQ 4217

Query: 355  RTSSTQQDNPQTSFPTCTPQRENPRTPCVQQD-----DPRASSPNRT------TQRENSR 403
              S+T Q  P +S  T +P    P T  V  +       R SS   T      T    S 
Sbjct: 4218 EESTTFQSWPSSSDTTPSP----PSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSE 4273

Query: 404  TSCAQRDNPKASRTS-SPNRATRD----NPRTSCAQRDNPRASS--PSRATRDNPTTSCA 456
             S     +P A+ T+  P R+        P TS     +   ++   S  T      S  
Sbjct: 4274 ESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTT 4333

Query: 457  QRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTS 516
               +PR+  T+    +T  +  +  +   + R  S       + TT         AS +S
Sbjct: 4334 FYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSS 4393

Query: 517  SPNRATRDNPRTSCAQRDNPRA----SSPNRAAR----DNPTTS-CAQRDNPRASRTSSP 567
              +  T  +P ++ A    P +    SSP         DN T S   +   P  S T SP
Sbjct: 4394 PGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSP 4453

Query: 568  N-------RATRDNPRTSCAQRDNPRASSPNRATRDNP--TTSCAQRDNPRASRTS--SP 616
            +         TR    T+     N + ++P   T  +     S     +P ++ T+  S 
Sbjct: 4454 HTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSA 4513

Query: 617  NRATRDNPRTSCAQRDNPRAS----SPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENP 672
            +  T      S     +P A+    SP R+T       S      P  S+      + N 
Sbjct: 4514 SSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSP-GSTQTMHFPESNT 4572

Query: 673  RTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRA--SSPNRTTQQENP--RTSCARRD 728
             +          SS + TI    P T+ A  ++P +  SSP  T     P   T+  R +
Sbjct: 4573 TSGRGEESTTSHSSTTHTISSA-PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSE 4631

Query: 729  NPRAS---------------SRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCT 773
               AS               S    +  ++  +  +       + P  T        S T
Sbjct: 4632 ESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTT 4691

Query: 774  RQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDN 833
               +P ++     +  +     ++      SSP+      +P       +   S+    +
Sbjct: 4692 FHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSS 4751

Query: 834  PKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNPR 893
            P ++ T       T + R      S        SS    T      P+S H         
Sbjct: 4752 PGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYH--------- 4802

Query: 894  NSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRP---QTS 950
             SSP      I    FP            S + S +SE   AS +   T G  P     +
Sbjct: 4803 -SSP----GSIATTHFP-----------ESSTTSGRSEESTASHSSPDTNGITPLPAHFT 4846

Query: 951  SPSRPAQHDPPQSSFGPTQYNLPSRAT----SSSHNPGHQSTSRTSSPVYPAAYGAPLTS 1006
            +  R A+      S G  +  L S AT    S+     + S+      + PA+  +   S
Sbjct: 4847 TSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSIS 4906

Query: 1007 PEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPR----------------APESE 1050
             EP+         H  A  AS+    L  +   F  +P                 A E  
Sbjct: 4907 GEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFT 4966

Query: 1051 PPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQSPQHEPLQLPA 1110
             PH +P      V       P  S     T F   P   +T+   H      H     P 
Sbjct: 4967 TPHSQPGSALSTVSPASTTVPGLSE--ESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPF 5024

Query: 1111 PVCIGY-RDAPRASSPPRQAPEPSLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIGHR 1169
            P   G+      A+       + S  F     A+  + +P+  +  +    PT   I   
Sbjct: 5025 PDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDLVGEPTTFYISPS 5084

Query: 1170 DA-----PSFSSPPRQAPEPSLFFQDPPGT-------SMESLAPST----DSLHGSPVLI 1213
                   P+ SS      E + F   P  T       S+E+LAP         +G   + 
Sbjct: 5085 PTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLAPGLCQEGQIWNGKQCVC 5144

Query: 1214 PQVCIGHRDAPRASSPPRHPPSDL 1237
            PQ  +G++      S P   P  L
Sbjct: 5145 PQGYVGYQCLSPLESFPVETPEKL 5168



 Score = 68.9 bits (167), Expect = 5e-11
 Identities = 307/1466 (20%), Positives = 471/1466 (32%), Gaps = 225/1466 (15%)

Query: 54   PRCPPAPEDPLSASTSGCQ--------------------SVVDPGL-RPGPKRGPSPSAG 92
            PR P A   P + ++SG                      S   PGL R       SP + 
Sbjct: 2530 PRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST 2589

Query: 93   ----LPEEGPTAAPRSRSRELEAVP------YLEGLTTSLC-GSCNEDPGSDPTSSPDSA 141
                LP    T+ P   S    + P         G TT+L  G  +    S P S+  + 
Sbjct: 2590 DTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTL 2649

Query: 142  TPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVGG 201
             PD T++S  V+  T       +P    L+      P     + + Q  P+    +P   
Sbjct: 2650 FPDSTTSSGIVEASTRVHSSTGSPR-TTLSPASSTSPGLQGESTTFQTHPASTHTTPSPP 2708

Query: 202  DAAGQKKEDTGGGGRSAGQ----HWARLRGESGLSLERHRSTL----TQASSMTPHSGP- 252
              A    E++    RS G     H+      SG S    +ST+      AS  TP S   
Sbjct: 2709 STATAPVEESTTYHRSPGSTPTTHFPASSTTSGHS---EKSTIFHSSPDASGTTPSSAHS 2765

Query: 253  ------RSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEISRASSTQ 306
                   STTS+ SP   +      +   P  S     T   + R+ +T   +S AS T 
Sbjct: 2766 TTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEA-STTFYSSPRSPTT--TLSPASMTS 2822

Query: 307  QETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQT 366
                  S+T    P   ST      AS+T   TP  S  S +    +P ++ T      T
Sbjct: 2823 LGVGEESTTSRSQP--GSTHSTVSPASTT---TPGLSEESTTVYSSSPGSTET------T 2871

Query: 367  SFPTCTPQRENPRTPCVQQDDP-----RASSPNRTTQRENSRTSCAQRDNPKASRTSSPN 421
             FP  T       T  V+ ++P     R +S + T   E+S TS    ++   +   SP 
Sbjct: 2872 VFPRST-------TTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEES--TAFPGSPA 2922

Query: 422  RATRDNPRT-SCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTS 480
                  P T + A       + PS +     T S A+         S+P+R +  +  T+
Sbjct: 2923 STQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETT 2982

Query: 481  CAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASS 540
                     S  + +  +  TT      +P A  T SP   T        +   +   S+
Sbjct: 2983 TLP-----GSPTTPSLSEKSTTFYTSPRSPDA--TLSPATTTSSGVSEESSTSHSQPGST 3035

Query: 541  PNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNP----RTSCAQRDNPRASSPNRATR- 595
               A  D+ TTS   ++ P AS +S  +     +P     +S  Q+     SSP      
Sbjct: 3036 HTTAFPDSTTTSGLSQE-PTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETT 3094

Query: 596  ----DNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTS 651
                D  T+   +   P  S T S +        TS   ++         TT Q  P +S
Sbjct: 3095 LLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQE-------ESTTFQSWPSSS 3147

Query: 652  CARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSP 711
                 D   S P  T       T+         S PS T     P T  +        S 
Sbjct: 3148 -----DTTPSPPGTTAAPVEVSTT-------YHSRPSST-----PTTHFSASSTTLGRSE 3190

Query: 712  NRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASS-PNRTIQQENLRT 770
              TT   +P  +       R+++   ++    P TS     +   ++ P  T        
Sbjct: 3191 ESTTVHSSPGATGTALFPTRSAT---SVLVGEPTTSPISSGSTETTALPGSTTTAGLSEK 3247

Query: 771  SCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQ 830
            S T   +PR+     +      +  ++      S P        P +     + + S+  
Sbjct: 3248 STTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTAS 3307

Query: 831  QDNPKTSCTKRDNLRPTCTQRDR--TQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQ 888
              +P ++ T    L P  T       +S +F   + G  S++     +N   S    ++ 
Sbjct: 3308 HSSPGSTDT---TLSPGSTTASSLGPESTTF---HSGPGSTETTLLPDNTTASGLLEAST 3361

Query: 889  WNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQ 948
              +    SPH T         P   T   G  T+  S        W +   + T    P 
Sbjct: 3362 PVHSSTGSPHTTLS-------PAGSTTRQGESTTFQS--------WPN--SKDTTPAPPT 3404

Query: 949  TSS---PSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPLT 1005
            T+S         H  P S+  PT +     A+S++     +ST+  SSPV      A  T
Sbjct: 3405 TTSAFVELSTTSHGSPSST--PTTH---FSASSTTLGRSEESTTVHSSPV------ATAT 3453

Query: 1006 SPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESEPPH----HEPPYIPP 1061
            +P P++   +  +       +S       H P       R  ES   H    H     P 
Sbjct: 3454 TPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPS 3513

Query: 1062 AVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPR 1121
                   +     S P  T    FP    TS                      G  +   
Sbjct: 3514 TTSALVEEPTSYHSSPGSTATTHFPDSSTTS----------------------GRSEEST 3551

Query: 1122 ASSPPRQAPEPSLLFQDLPRASTESLV--PSMDSLHECPHIPTPVCIGHRDAPSFSSPPR 1179
            AS   + A    +    LP  ST S++   S  S      + T    G    P  S    
Sbjct: 3552 ASHSSQDATGTIV----LPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLS---- 3603

Query: 1180 QAPEPSLFFQDPPGTSMESLAPSTDSLHGSPVLIPQVCIGHRDAPRASSPPRHPPSDLAF 1239
               E S  F   P +   +L+P++ +  G    + +        P ++     P S    
Sbjct: 3604 ---EKSTTFHSSPRSPATTLSPASTTSSG----VSEESTTSHSRPGSTHTTAFPDS---- 3652

Query: 1240 LAPSPSPGSSGGSRGS-APPGETRHNLEREEYTVLADLPPPRRLAQRQPGPQAQCSSGGR 1298
               + +PG S  S  S + PG T       + T+L         +Q      +   S   
Sbjct: 3653 ---TTTPGLSRHSTTSHSSPGST-------DTTLLPASTTTSGSSQESTTSHSSSGSTDT 3702

Query: 1299 THSPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPSRQVTML 1358
              SPG +     FGQE     ++              S G  +   R  S   S + T+ 
Sbjct: 3703 ALSPG-STTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLS 3761

Query: 1359 PAKQAE--LTRRSQAEPPHPWSPEKRPEGDRQLQGSPLPPRTSARTPERELRTQRPLESG 1416
            PA      L   S A   HP S    P              T  R+P     T  P  S 
Sbjct: 3762 PASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASST 3821

Query: 1417 QAGPRQPLGVWQSQEEPPGSQGPHRH 1442
             +G  +   ++ S  +  G+     H
Sbjct: 3822 TSGHSEKSTIFHSSPDASGTTPSSAH 3847



 Score = 32.0 bits (71), Expect = 7.4
 Identities = 75/342 (21%), Positives = 110/342 (32%), Gaps = 61/342 (17%)

Query: 949  TSSPSRPAQHDP--PQSSFGPT-QYNLPSRATS----SSHNPGHQSTSR--------TSS 993
            T+S S P+  DP    S +G +  +   S AT     SS N GH   S         T +
Sbjct: 177  TTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSSTNSGHSEESTVSHSGPGATGT 236

Query: 994  PVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESEPPH 1053
             ++P+     +   EP   P         A   S+    L      F+  PR+P+     
Sbjct: 237  TLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPD----R 292

Query: 1054 HEPPYIPPAVCIGHRDAPRASSP-PRHTQFDP----FPFLPDTSDAEHQCQSPQHEPLQL 1108
               P    +  +  +     S P P HT   P     P +   S A H         L  
Sbjct: 293  TLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTL-- 350

Query: 1109 PAPVCIGYRDAPRASSPPRQAPEPSLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIGH 1168
                      +P  ++P    PE S  F   P  +  + +P   +        TPV    
Sbjct: 351  ----------SPGTTTPSSLGPE-STTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSST 399

Query: 1169 RDAPSFSSPPRQAP---EPSLFFQDPPGTSMESLAPS---------TDSLHGSPVLIP-- 1214
                +  SP        EP+  FQ  P +   S APS         + + H SP   P  
Sbjct: 400  GSPHTTLSPSSSTTHEGEPTT-FQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTT 458

Query: 1215 -----QVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGG 1251
                    +GH +     S P H         P P+  ++ G
Sbjct: 459  HFSASSTTLGHSE----ESTPVHSSPVATATTPPPARSATSG 496


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 233/1083 (21%), Positives = 368/1083 (33%), Gaps = 110/1083 (10%)

Query: 245  SMTPHSGPRSTTSQASPAQRDTAQAAS---TREIPRASSPHRITQRDTSRASSTQQEISR 301
            S+TP       T+   P+   T   A+   T  +   S+P  +T    S       E S 
Sbjct: 355  SITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTP--LTNMPVSTILVASSEAST 412

Query: 302  ASSTQQETSRASSTQEDTPRASSTQEDTPRASST--QWNTPRASSPSRSTQLDNPR---- 355
             S+   ++    +T  +   + +T EDT  A+ST  + +TP  S P  +T + +      
Sbjct: 413  TSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNL 472

Query: 356  ------------TSSTQQDNPQT----SFPTCTP-QRENPRTPCVQQDDPRASSPNRTTQ 398
                        TS+    +P T    S PT TP +   P T       P ASS   T  
Sbjct: 473  STTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLS 532

Query: 399  RENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQR 458
                 TS     + +AS +S+    T   P ++ ++   P  + P        + +    
Sbjct: 533  TTPVDTSTPVTTSSEASSSSTTPEGT-SIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTS 591

Query: 459  DNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSP 518
              P  S T     +   +  T+      P ++   R T     TS +      AS  +S 
Sbjct: 592  TTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGT---TITSMSVSTTLVASSEAST 648

Query: 519  NRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASR-------TSSPNRAT 571
               T  +  T         +SS        PT++  +   P  S         SS     
Sbjct: 649  LSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTL 708

Query: 572  RDNPRTSCAQRDNPRASSPNRATRDN---PTTSCAQRDNPRASRTSSPNRATRDNPRTSC 628
               P  +         +S +  T D    PT++ ++   P  S   S    T     T  
Sbjct: 709  STTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLS 768

Query: 629  AQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENP-----RTSCALRDNPR 683
                 P  +S + TT   S   SC+       S P  T  + +P       S     +P 
Sbjct: 769  T---TPLDTSTHITT---STEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPE 822

Query: 684  ASSPSRT-IQQENPRT-----SCAQRDDPRASSPNRT-TQQENPRTSCARRDNPRASSRN 736
            AS+ S T +   +P T     S +       S P  T ++   P TS        A+S  
Sbjct: 823  ASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAI 882

Query: 737  RTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQ-DNPRTSSPNRAT---RDNPR 792
             T+      TS    ++  A S   T +  ++ TS   +   P TS P+  T       R
Sbjct: 883  STLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEAR 942

Query: 793  TSCAQRDNLRASSPIRATQQ--DNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQ 850
            T  A    +  S+P+  + +   +P T    +IP S+ ++   P TS T   +     ++
Sbjct: 943  TLSA--TPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTS-TPVSHTLVANSE 999

Query: 851  RDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRST--QWNNPRNSSPHRTNKDIPWAS 908
                 +     + P T+S++  +       +S   ST  + + P    P  T       +
Sbjct: 1000 ASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSET 1059

Query: 909  FPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPT----QGDRPQTSSPSRP---AQHDPP 961
              L  T +D     +      S    A     PT    +G  P TS P         +  
Sbjct: 1060 STLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEAS 1119

Query: 962  QSSFGPTQYNLP-SRATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGH 1020
              S  P   ++P + +T +S +P   +   TS P  P + G   T+P  S P     +  
Sbjct: 1120 TLSTTPVDTSIPVTTSTEASSSP--TTAEGTSIPTSPPSEG---TTPLASMPVSTTLVVS 1174

Query: 1021 RDAPRASSPPRYLQHDPFPFFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHT 1080
             +A   S+ P     D            S PP  E   +P +   G R  P  S P RHT
Sbjct: 1175 SEANTLSTTP----VDSKTQVATSTEASSPPPTAEVTSMPTST-PGERSTPLTSMPVRHT 1229

Query: 1081 QFDPFPFLPDTSDAEHQCQSP--QHEPLQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQD 1138
                      +S+A     SP     P+   A        A   S P     E S L   
Sbjct: 1230 PV-------ASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTS 1282

Query: 1139 LPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMES 1198
            +P ++T    P   +L     + TPV    +     S+    +P P+     P  T  E 
Sbjct: 1283 IPVSTTLVTSPEASTL-----LTTPV--DTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEG 1335

Query: 1199 LAPSTDSLHGSPVLIPQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPG----SSGGSRG 1254
              P T S+  +  L+    I         +      S  A  +P+ S G    +S  S G
Sbjct: 1336 RTPLT-SIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEG 1394

Query: 1255 SAP 1257
            + P
Sbjct: 1395 TTP 1397



 Score = 84.7 bits (208), Expect = 1e-15
 Identities = 229/1033 (22%), Positives = 334/1033 (32%), Gaps = 155/1033 (15%)

Query: 120  TSLCGSCNEDPGSDPTSSPDSATP---DDTSNSSSVDWD-----TVERQEEEAPSWDELA 171
            TS+  S   +  +  TS P S TP    + SN S+   D     T   +   +P   E+ 
Sbjct: 440  TSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVN 499

Query: 172  VMIPRRPREG------------PRADSSQRAPSLL---TRSPVGGDAAGQKKEDTGGG-- 214
             M    P EG            P A S     S     T +PV   +       T  G  
Sbjct: 500  SMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTS 559

Query: 215  -GRSAGQHWARLRGESGLSLERHRSTLTQASSMTP-HSGPRSTTSQASPAQRDTAQAAST 272
               S     +       +S     S+    +S TP  S    TTS  + +   TA+  S 
Sbjct: 560  IPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSM 619

Query: 273  REIPRASSPHRITQRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDT--P 330
                 +     IT    S       E S  S+T  +++   +T  +   +S+T E T  P
Sbjct: 620  PTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMP 679

Query: 331  RASSTQWNTPRASSPSRST---------------QLDNPRTSSTQQDNPQT-----SFPT 370
             ++ T+ +TP  S P  +T                   P T+ST+  +  T     S PT
Sbjct: 680  TSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPT 739

Query: 371  CTP-QRENPRT-------------PCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASR 416
             TP +   P T                    P  +S + TT  E S +            
Sbjct: 740  STPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPIS 799

Query: 417  TSSPNRATRDNPRTSCAQRDNPRASSPSRATRDN---PTTSCAQRDNPR-ASRTSSPNRA 472
            T S       +   S     +P AS+ S    D+    TTS     +P  A  TS P   
Sbjct: 800  TPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTST 859

Query: 473  TRD--NPRTSCAQRDNPRASSPSRATRDNP-------TTSCAQRDNPRASR-----TSSP 518
              +   P TS        A+S        P       T S   R +P  S      TS+P
Sbjct: 860  YSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTP 919

Query: 519  NRATRDNPRTSCAQRDNPRASSPNRAARDNP-------TTSCAQRDNPRASR-----TSS 566
               +   P TS      P  SS  R     P       TTS     +P  +      TS+
Sbjct: 920  GEGS--TPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTST 977

Query: 567  PNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRT 626
            P+  T   P TS        A+S        P  S         + +  P       P +
Sbjct: 978  PSEGT--TPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTS 1035

Query: 627  SCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQ----------------- 669
            + ++   P    P  TT   S  TS         S+P  T  Q                 
Sbjct: 1036 TPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTST 1095

Query: 670  ----ENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQEN-PRTSC 724
                  P TS  +      SS + T+      TS        ASS   T +  + P +  
Sbjct: 1096 YSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPP 1155

Query: 725  ARRDNPRA----------SSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCT- 773
            +    P A          SS   T+      +      +  ASSP  T +  ++ TS   
Sbjct: 1156 SEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPG 1215

Query: 774  RQDNPRTSSPNRATR-DNPRTSCAQRDNLRASSPI--RATQQDNPRTCIQQNIPRSSSTQ 830
             +  P TS P R T   +   S      +  S+P+   A    +P T    ++P S++++
Sbjct: 1216 ERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSE 1275

Query: 831  QDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRST--Q 888
                 TS      L  T  +     +       P  +S++  +       +S   ST  +
Sbjct: 1276 GSTLLTSIPVSTTL-VTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSE 1334

Query: 889  WNNPRNSSPHRTNKDIPWASFPLRPTQSDG--PRT------SSPSRSKQSEVPWASIALR 940
               P  S P  T      A   L  T  D   P T      SSP+ S+ + +P ++    
Sbjct: 1335 GRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSN---- 1390

Query: 941  PTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAY 1000
            P++G  P TS    P    P  SS   T     S     +  PG  S   TSSP      
Sbjct: 1391 PSEGTTPLTSI---PVSTTPVVSSEASTL----SATPVDTSTPGTTSAEATSSPTTAEGI 1443

Query: 1001 GAPLTSPEPSQPP 1013
              P ++P   + P
Sbjct: 1444 SIPTSTPSEGKTP 1456



 Score = 82.8 bits (203), Expect = 4e-15
 Identities = 213/1033 (20%), Positives = 352/1033 (34%), Gaps = 118/1033 (11%)

Query: 29   PEEAHGARYQELRSPSGAEVPYCDL--PRCPPAPEDPLSASTSGCQSVVDPGLRPGPKRG 86
            P  A G   + + +PS    P   +     P A  +  + ST+   + +   +    +  
Sbjct: 2733 PTTAEGTSMR-ISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIP--VTTSTEAS 2789

Query: 87   PSPSAGLPEEGPTAAPRSRSRELEAVPYLEGLTTSLCGSCNEDPGSDPTSSPDSATPDDT 146
             SP+       PT+ P   S  L ++P       S       + G+  T+  D++TP  T
Sbjct: 2790 SSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVAS------SEAGTLSTTPVDTSTPVTT 2843

Query: 147  SNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGPRADSSQRAP----SLLTRSPVGGD 202
            S  +S    T E       +  E + ++   P       SS+ +      + T  PV   
Sbjct: 2844 STKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTS 2903

Query: 203  AAGQKKEDTGGGGR--------------SAGQHWARLRGESGLSLE------RHRSTLTQ 242
              G     T  G                S       + G    +L       R   T + 
Sbjct: 2904 TEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSA 2963

Query: 243  ASSMTPHSGPRSTTSQASPAQRDTAQAA-STREIPRASSPHRITQRDTSRASSTQQEISR 301
             +S +P +   ++   ++P +R T   + S   +P ASS      R T   +ST    S 
Sbjct: 2964 EASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSR-TPADTSTPVTTST 3022

Query: 302  ASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASS------PSRSTQLDNPR 355
             +S+   T+  +     TP   ST   +   S+T    P AS+       S S  + +  
Sbjct: 3023 EASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTE 3082

Query: 356  TSSTQQDNPQTSFPTCT-PQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKA 414
             SS+      TS P  T  +   P T       P  SS   T       TS     + +A
Sbjct: 3083 VSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEA 3142

Query: 415  SRTSSPNRATRDNPRTSCAQRDNPRASSPSR----ATRDNPTTSCAQRDNPRASRTSSPN 470
              + + +  T   P ++ ++   P    P       + ++ T S    D      TS+P 
Sbjct: 3143 HSSPTTSEGT-SMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVD------TSTPV 3195

Query: 471  RATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSC 530
              + +   ++ A+  +   S+PS      P TS    + P AS  +S    T  +  T  
Sbjct: 3196 TTSTEATSSTTAEGTSIPTSTPSEGM--TPLTSVPVSNTPVASSEASILSTTPVDSNTPL 3253

Query: 531  AQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSP 590
                   +S P       PT++ ++   P    TS P   T     T  +   +  +++P
Sbjct: 3254 TTSTEASSSPPTAEGTSMPTSTPSEGSTP---LTSMPVSTT-----TVASSETSTLSTTP 3305

Query: 591  NRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRT 650
               +    T S A    P A  TS P                       +  ++  +P T
Sbjct: 3306 ADTSTPVTTYSQASSSPPIADGTSMPT----------------------STYSEGSTPLT 3343

Query: 651  SCARRDDPRASSPNRTIQQENPRTSCALRDNPRAS-SPSRTIQQENPRTSCAQRDDPRAS 709
            + +    P  SS   T+      TS  +  +  AS SP+       P +S ++   P AS
Sbjct: 3344 NMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLAS 3403

Query: 710  SPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLR 769
             P  TT              P  SS   T+      ++     +  ASS     +  +L 
Sbjct: 3404 MPVSTT--------------PVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLP 3449

Query: 770  TSCTRQ-DNPRTSSPNRATR-DNPRTSCAQRDNLRASSPIRATQQDN--PRTCIQQNIPR 825
            TS T +   P +  P   T   +   S      +  S+P+  +   N  P T    ++P 
Sbjct: 3450 TSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPT 3509

Query: 826  SSSTQQDNPKT----SCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPS 881
            S++ +   P T    S T   +   +        S +F   +   SSS    Q   +R S
Sbjct: 3510 STAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMS 3569

Query: 882  SPHR-STQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALR 940
            +P   S+       SS + T+ +   AS P  P+       ++ ++S  +  P   I L 
Sbjct: 3570 TPSEGSSSLTTMLLSSTYVTSSE---ASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLP 3626

Query: 941  PTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAY 1000
             +      T     P        S   T   LP      +  P   ST  +SSPV P   
Sbjct: 3627 MSTPSEVSTPLTIMPVSTTSVTISEAGTASTLP----VDTSTPVITSTQVSSSPVTPEGT 3682

Query: 1001 GAPLTSPEPSQPP 1013
              P+ +P     P
Sbjct: 3683 TMPIWTPSEGSTP 3695



 Score = 77.4 bits (189), Expect = 2e-13
 Identities = 265/1286 (20%), Positives = 441/1286 (34%), Gaps = 203/1286 (15%)

Query: 53   LPRCPPAPEDPLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTAAPRSRSRELEAV 112
            L   P     P+  ST+   S       P P  G S +   P EG TA        L ++
Sbjct: 1828 LSTTPVDSNSPVVTSTAVSSS-------PTPAEGTSIATSTPSEGSTA--------LTSI 1872

Query: 113  PYLEGLTTSLCGSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAV 172
            P     TT++  S          ++  S TP  TS        T   Q   +P+  + + 
Sbjct: 1873 PVS---TTTVASS---------ETNTLSTTPAVTSTPV-----TTYAQVSSSPTTADGSS 1915

Query: 173  MIPRRPREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLS 232
            M    PREG       R P  LT  PV        + +T                    +
Sbjct: 1916 MPTSTPREG-------RPP--LTSIPVSTTTVASSEINT-----------------LSTT 1949

Query: 233  LERHRSTLTQASSMTPHSGPRSTTSQASPAQRD------TAQAASTREIPRASSPHRITQ 286
            L   R+ +T  S  +        TS  +PA  +      +   ++T  +   +S    T 
Sbjct: 1950 LADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTP 2009

Query: 287  RDTSRASSTQQEISRASSTQQETSRASST-QEDTPRASSTQEDTPRASSTQWNTPRASSP 345
             DTS  ++T  E S + +T   TS  +ST  E T   +     T    S++ NT   +  
Sbjct: 2010 VDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPV 2069

Query: 346  SRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTS 405
               TQ+ N   +S+      +S     P   +P    +    P +++P  + +     T+
Sbjct: 2070 DSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSI----PLSTTPVASPEASTLSTT 2125

Query: 406  CAQRDNPKASRT---SSPNRATRDNPRTSC-AQRDNPRASSPSRATRDNPTTSCAQRDNP 461
                ++P  + T   SSP      + +TS  + R  P  S P   T    +        P
Sbjct: 2126 PVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTP 2185

Query: 462  RASRTSSPNRA-TRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNR 520
              + T   N    R +P TS  +  +   S+PS  +   P TS      P  +  +S   
Sbjct: 2186 VDTSTPVTNSTEARSSPTTS--EGTSMPTSTPSEGS--TPFTSMPVSTMPVVTSEASTLS 2241

Query: 521  ATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRAS-------------RTSSP 567
            AT  +  T         +S         PT++ ++   P  S              T S 
Sbjct: 2242 ATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLST 2301

Query: 568  NRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRA-------------SRTS 614
                 + P T+  +  +P    P       PT++ ++ + P               + T 
Sbjct: 2302 TPVDSNTPFTTSTEASSP---PPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTL 2358

Query: 615  SPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRT 674
            S   A    P T+ +Q      SSP        P ++ +    P  S P  T+   +   
Sbjct: 2359 STTPADTSTPVTTYSQA----GSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEA 2414

Query: 675  SCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASS 734
            S         S+P  T  + +   + A+      S P+  T    P  S      P  SS
Sbjct: 2415 STHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGT---TPLASMPVSTTPVVSS 2471

Query: 735  RNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRD--NPR 792
               T+      TS     +  ASS   T +   +  S   + +   +S   +T    +P 
Sbjct: 2472 EAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPE 2531

Query: 793  TSCAQRDNLRASSPI-RATQQDNPRTCIQ-QNIPRSSSTQQDNP---------------- 834
             S      + ++SP+  +T+  +  T  +  ++P S+ ++   P                
Sbjct: 2532 ASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEA 2591

Query: 835  -KTSCTKRDNLRPTCTQRDRTQSFSFQRDN--PGTSSSQCCTQKENLRPSSPHRSTQWNN 891
               S T  D   P  T  + + S +  +D   P ++ S+  T   ++  S+   ++   +
Sbjct: 2592 STLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEAS 2651

Query: 892  PRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQTS- 950
              +++P  T   +         T S G  +SSP+ ++ S +P ++    P +   P T+ 
Sbjct: 2652 TLSTTPVDTRTLV---------TTSTGT-SSSPTTAEGSSMPTST----PGERSTPLTNI 2697

Query: 951  --SPSRPAQHDPPQSSFGPTQYNLP---SRATSSSHNPGHQSTSRTSSPVYPAAYGAPLT 1005
              S +  A  +    S  P   + P   S   SSS      ++ R S+P   +    PLT
Sbjct: 2698 LVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTP---SDGSTPLT 2754

Query: 1006 SPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESEPPHHEPPYIPPAVCI 1065
            S   S  P A       +  AS+          P      A  S P   E   +P +   
Sbjct: 2755 SILVSTLPVA-------SSEASTVSTTAVDTSIPVTTSTEA-SSSPTTAEVTSMPTSTP- 2805

Query: 1066 GHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRASS- 1124
                 P  S P  HT             A  +  +    P+    PV    + +   ++ 
Sbjct: 2806 SETSTPLTSMPVNHTPV-----------ASSEAGTLSTTPVDTSTPVTTSTKASSSPTTA 2854

Query: 1125 -----PPRQAPEPSLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPR 1179
                 P   A E S L   +P ++T        +L   P + T + +    +   SS P 
Sbjct: 2855 EGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTP-VDTSIPV--TTSTEGSSSPT 2911

Query: 1180 QAPEPSLFFQDPPGTSMESLAPSTDSLHGSPVLIPQVCIGHRDAPRASSPP---RHPPSD 1236
             A           GTSM    PS  S   + +L+  V +   +A   S+ P   R P + 
Sbjct: 2912 TAE----------GTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTT 2961

Query: 1237 LAFLAPSPSPGSSGGSRGSAPPGETR 1262
             A  + SP+  + G S   + PGE R
Sbjct: 2962 SAEASSSPTT-AEGTSMPISTPGERR 2986



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 271/1303 (20%), Positives = 443/1303 (33%), Gaps = 183/1303 (14%)

Query: 53   LPRCPPAPEDPLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTAAPRSRSRELEAV 112
            L   P     P+  ST+   S       P P  G S +   P EG TA        L ++
Sbjct: 1475 LSTTPVDSNSPVVTSTAVSSS-------PTPAEGTSIAISTPSEGSTA--------LTSI 1519

Query: 113  PYLEGLTTSLCGSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAV 172
            P     TT++  S   +  S  T+   ++TP  T + +S    T +    +  ++ E + 
Sbjct: 1520 PVS---TTTVASS---EINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGST 1573

Query: 173  MIPRRPREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLS 232
             +   P       SS+   + L+ +P+          +      + G          G  
Sbjct: 1574 PLTSLPVSTMLVVSSEA--NTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSP 1631

Query: 233  LERHRSTLTQAS-SMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSR 291
            L      LT    S TP + P ++T   +P   ++    ST E+  + +P   T   TS 
Sbjct: 1632 L------LTSIPVSTTPVASPEASTLSTTPVDSNSPVITST-EVSSSPTPAEGTSMPTS- 1683

Query: 292  ASSTQQEISRASSTQQETSRASST---------QEDTPRASSTQ----------EDTPRA 332
             + T+      S T + T  ASS             TP  +ST+             P +
Sbjct: 1684 -TYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNS 1742

Query: 333  SSTQWNTPRASSPSRSTQL---------------DNPRTSSTQQDNPQTSFPTCTPQREN 377
            + ++  TP  S P  +T +                 P T+ST+     TS PT       
Sbjct: 1743 TPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTE----ATSSPTTAEGTSI 1798

Query: 378  PRTPCVQQDDPRASSPNRTTQRENSR-----TSCAQRDNPKASRT---SSPNRATRDNPR 429
            P +   +   P  S+P   T   NS      T+    ++P  + T   SSP  A   +  
Sbjct: 1799 PTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIA 1858

Query: 430  TSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRA 489
            TS      P   S +  +    TT+ A  +    + T S   A    P T+ AQ     +
Sbjct: 1859 TS-----TPSEGSTALTSIPVSTTTVASSE----TNTLSTTPAVTSTPVTTYAQ----VS 1905

Query: 490  SSPSRATRDNPTTSCAQRDNPRAS--------------RTSSPNRATRDNPRTSCAQRDN 535
            SSP+ A   +  TS  +   P  +               T S   A    P T+ +Q   
Sbjct: 1906 SSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQ--- 1962

Query: 536  PRASSPNRA-ARDNPTTSCAQRDNPRASRTSSPNRATRDNPRT---------SCAQRDNP 585
              +SSP  A     PT + ++   P  S   S          T         + A     
Sbjct: 1963 -ASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTE 2021

Query: 586  RASSPNRATRDNPTTSC-AQRDNPRASR-------TSSPNRATRDNPRTSCAQRDNPRAS 637
             +SSP  A   +  TS  ++R  P A          SS        P  S  Q  N   +
Sbjct: 2022 GSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEA 2081

Query: 638  SPNRTTQQDSPRTSCARRDDPRASS-PNRTIQQENPRTSCALRDNPRASSPSRTIQQENP 696
            S + T +  S   S      P  +S P  T    +P  S        ++SP  T  + + 
Sbjct: 2082 SSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSS 2141

Query: 697  RTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRA 756
                 +    + S+    + +  P TS        ASS   T+      TS    ++  A
Sbjct: 2142 SPIPTEGTSMQTST---YSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEA 2198

Query: 757  SSPNRTIQQENLRTSCTRQ-DNPRTSSP-NRATRDNPRTSCAQRDNLRASSPIRATQQ-- 812
             S   T +  ++ TS   +   P TS P +         S      +  S+P+  + +  
Sbjct: 2199 RSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEAT 2258

Query: 813  DNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCC 872
             +P T    +IP S+ ++   P TS      L    ++     +     + P T+S++  
Sbjct: 2259 SSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVAN-SEVSTLSTTPVDSNTPFTTSTEAS 2317

Query: 873  TQKENLRPSSPHRST--QWNNPRNSSPHRTNKDIPWASFPLRPTQSD--------GPRTS 922
            +       +S   ST  + N P    P  T     + +  L  T +D            S
Sbjct: 2318 SPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGS 2377

Query: 923  SPSRSKQSEVPWASIALRPTQGDRPQTSSP-SRPAQHDPPQSSFGPTQYNLPSRATSSSH 981
            SP+ +  + +P ++     ++G  P TS P S         S+   T  +  +  T+S+ 
Sbjct: 2378 SPTTADDTSMPTSTY----SEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTE 2433

Query: 982  NPGHQSTSR-TSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPF 1040
                 +T+  TS P  P + G   T+P  S P     +   +A   S+ P     D    
Sbjct: 2434 ASSSPTTAEGTSIPTSPPSEG---TTPLASMPVSTTPVVSSEAGTLSTTP----VDTSTP 2486

Query: 1041 FPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQS 1100
                    S P   E   +P  +      +   +S P  T     P     +        
Sbjct: 2487 MTTSTEASSSPTTAEDIVVP--ISTASEGSTLLTSIPVSTT----PVASPEASTLSTTPV 2540

Query: 1101 PQHEPLQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQDLPRASTESLVPSMDSLHECPHI 1160
              + P+     +      A   S P     E S   + +P  ST+ L  S  S      +
Sbjct: 2541 DSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMP-VSTKPLASSEASTLSTTPV 2599

Query: 1161 PTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLAPSTDSLHGSPVLIPQVCIGH 1220
             T + +    +   SS P  A +          TSM    PS  S   + +L+  + +  
Sbjct: 2600 DTSIPV--TTSTETSSSPTTAKD----------TSMPISTPSEVSTSLTSILVSTMPVAS 2647

Query: 1221 RDAPRASSPP---RHPPSDLAFLAPSPSPGSSGGSRGSAPPGE 1260
             +A   S+ P   R   +     + SP+  + G S  ++ PGE
Sbjct: 2648 SEASTLSTTPVDTRTLVTTSTGTSSSPTT-AEGSSMPTSTPGE 2689



 Score = 71.2 bits (173), Expect = 1e-11
 Identities = 276/1291 (21%), Positives = 427/1291 (33%), Gaps = 154/1291 (11%)

Query: 53   LPRCPPAPEDPLSASTSGCQS--VVDPGLRPG--PKRGPSPSAGLPEEGPTAAPRSRSRE 108
            L   P     P++ ST    S    D    P   P  G +P   +P    T    S +  
Sbjct: 708  LSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVS-KTLLTSSEAST 766

Query: 109  LEAVPYLEG--LTTSLCGSCNED-------PGSDP-------TSSPDSATPDDTSNSSSV 152
            L   P      +TTS   SC+         P S P       TS P S TP  +  +S++
Sbjct: 767  LSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTL 826

Query: 153  DWDTVERQEEEAPSWDELAVMIPRRPREGPRADSSQ-RAPSLLTRSPVGGDAAGQKK--- 208
                V+       S +  +   P      P +  S+ R P  LT  PV            
Sbjct: 827  STTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTP--LTSMPVSTTLVATSAIST 884

Query: 209  -----EDTGGGGRSAGQHWARLRGESGLSL------ERHRSTLTQASSMTPHSGPRSTTS 257
                  DT     ++ +  +      G S+      E      +   S TP     + T 
Sbjct: 885  LSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTL 944

Query: 258  QASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQE---------ISRASSTQQE 308
             A+P    T    ST      SSP   T   TS  +ST  E         +S       E
Sbjct: 945  SATPVDTSTPVTTSTEA---TSSP--TTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSE 999

Query: 309  TSRASSTQED--TPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQT 366
             S  S+T  D  TP  +ST+  +P  ++   + P ++    ST L     S+T   + +T
Sbjct: 1000 ASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSET 1059

Query: 367  SFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSC-AQRDNPKASRTSSPNRATR 425
            S  + TP   +  TP       +ASS + T    +  TS  ++   P  S   S      
Sbjct: 1060 STLSTTP--ADTSTPVTTYS--QASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVS 1115

Query: 426  DNPRT-SCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQR 484
                T S    D     + S     +PTT+        +  TS P+  T   P  S    
Sbjct: 1116 SEASTLSTTPVDTSIPVTTSTEASSSPTTA-----EGTSIPTSPPSEGT--TPLASMPVS 1168

Query: 485  DNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNR- 543
                 SS +      P  S  Q      + +  P       P ++  +R  P  S P R 
Sbjct: 1169 TTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRH 1228

Query: 544  ---AARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTT 600
               A+ +  T S +  D      TS+    T  +P T+         +S       +   
Sbjct: 1229 TPVASSEASTLSTSPVDTSTPVTTSA---ETSSSPTTAEGTSLPTSTTSEGSTLLTSIPV 1285

Query: 601  SCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRA 660
            S     +P AS   +    T+    TS     N  +SSP        P ++ +    P  
Sbjct: 1286 STTLVTSPEASTLLTTPVDTKGPVVTS-----NEVSSSPTPAEGTSMPTSTYSEGRTPLT 1340

Query: 661  SSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENP 720
            S P  T    +   S         S+P  T  +     + ++      S+P+  T    P
Sbjct: 1341 SIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGT---TP 1397

Query: 721  RTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQ-DNPR 779
             TS      P  SS   T+      TS     +  A+S   T +  ++ TS   +   P 
Sbjct: 1398 LTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPL 1457

Query: 780  TSSP-NRATRDNPRTSCAQRDNLRASSPI----RATQQDNPR--TCIQQNIPRSSSTQQD 832
             S P +     N   S      + ++SP+      +    P   T I  + P   ST   
Sbjct: 1458 KSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALT 1517

Query: 833  NPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRST--QWN 890
            +   S T         ++ +   +       P T+ SQ  +       +S   ST  + +
Sbjct: 1518 SIPVSTT-----TVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGS 1572

Query: 891  NPRNSSPHRTNKDIPWASFPLRPTQSDGPR--TSSPSRSKQSEVPWASIAL-RPTQGDRP 947
             P  S P  T   +   +  L  T  D     T+S   S  +    +S+ +  P++G   
Sbjct: 1573 TPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPL 1632

Query: 948  QTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSP 1007
             TS P        P++S         S     S++P   ST  +SSP        P ++ 
Sbjct: 1633 LTSIPVSTTPVASPEAS-------TLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTY 1685

Query: 1008 EPSQPPCAVCIGHRDAPRASSPPRYLQHDPF----PFFPEPRAPESEPPHHEPPYIPPAV 1063
               + P    I  R  P ASS    L   P     P      A  S P   E   +P   
Sbjct: 1686 TEGRTP-LTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEA-RSSPTTSEGTSMP--- 1740

Query: 1064 CIGHRDAPRASSPPRHTQFDPFPFLP--DTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPR 1121
                      S+P   T   P   +P   T     +  +    P+    PV      +  
Sbjct: 1741 ---------NSTPSEGT--TPLTSIPVSTTPVLSSEASTLSATPIDTSTPV----TTSTE 1785

Query: 1122 ASSPPRQAPEPSLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQA 1181
            A+S P  A   S+         T +L   M  L   P   T   + + +A + S+ P  +
Sbjct: 1786 ATSSPTTAEGTSI--------PTSTLSEGMTPLTSTPVSHT--LVANSEASTLSTTPVDS 1835

Query: 1182 PEP---SLFFQDPP----GTSMESLAPSTDSLHGSPVLIPQVCIGHRDAPRASSPP---R 1231
              P   S      P    GTS+ +  PS  S   + + +    +   +    S+ P    
Sbjct: 1836 NSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTS 1895

Query: 1232 HPPSDLAFLAPSPSPGSSGGSRGSAPPGETR 1262
             P +  A ++ SP+  + G S  ++ P E R
Sbjct: 1896 TPVTTYAQVSSSPTT-ADGSSMPTSTPREGR 1925



 Score = 71.2 bits (173), Expect = 1e-11
 Identities = 221/1071 (20%), Positives = 345/1071 (32%), Gaps = 138/1071 (12%)

Query: 53   LPRCPPAPEDPLSASTSGCQSVVDPG----LRPGPKRGPSPSAGLP--------EEGPTA 100
            L   P     P + ST G  S    G        P    +P AG+P         EG T 
Sbjct: 2005 LSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTL 2064

Query: 101  APR--------SRSRELEAVPYLEGLTTSLCGSCNEDPGSDPTSSPDSATPDDTSNSSSV 152
            +          + S E  +    EG + ++       P    TS P S TP  +  +S++
Sbjct: 2065 STTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLL--TSIPLSTTPVASPEASTL 2122

Query: 153  DWDTVERQEEEAPSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVG----GDAAGQKK 208
                V+       S +  +  IP        +  S R   L T  PV       +A    
Sbjct: 2123 STTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPL-TSMPVSTTVVASSAISTL 2181

Query: 209  EDTGGGGRSAGQHWARLRGESGLSLERHRSTLTQASSMTPHSG-PRST---------TSQ 258
              T     +   +    R     S      T T +   TP +  P ST         T  
Sbjct: 2182 STTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLS 2241

Query: 259  ASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQE---------ISRASSTQQET 309
            A+P    T    ST      SSP   T   TS  +ST  E         +S       E 
Sbjct: 2242 ATPVDTSTPVTTSTEA---TSSP--TTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEV 2296

Query: 310  SRASSTQED--TPRASSTQEDT----------PRASSTQWNTPRASSPSRSTQLDNPRTS 357
            S  S+T  D  TP  +ST+  +          P ++S++ NTP    P  +T + +  TS
Sbjct: 2297 STLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETS 2356

Query: 358  STQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRT-TQRENSRTSCAQRDNPKASR 416
            +       TS P  T  +    +P    D    S P  T ++     TS      P  S 
Sbjct: 2357 TLSTTPADTSTPVTTYSQAG-SSPTTADD---TSMPTSTYSEGSTPLTSVPVSTMPVVSS 2412

Query: 417  TSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDN 476
             +S +  T  +  T         +S  +      PT+  ++   P AS   S        
Sbjct: 2413 EASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSE 2472

Query: 477  PRT-SCAQRDNPRASSPSRATRDNPT-------------------TSCAQRDNPRASRTS 516
              T S    D     + S     +PT                   TS      P AS  +
Sbjct: 2473 AGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEA 2532

Query: 517  SPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNP-RASRTSSPNRATRDNP 575
            S    T  +  +         +S+ +      PT++ ++   P R+   S+   A+ +  
Sbjct: 2533 STLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEAS 2592

Query: 576  RTSCAQRDNPRASSPNRATRDNPT-------------------TSCAQRDNPRASRTSSP 616
              S    D     + +  T  +PT                   TS      P AS  +S 
Sbjct: 2593 TLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEAST 2652

Query: 617  NRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSC 676
               T  + RT         +SSP        P ++   R  P  +    T    N   S 
Sbjct: 2653 LSTTPVDTRT-LVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEAST 2711

Query: 677  ALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRN 736
                    S+P  T  + +   + A+    R S+P   +    P TS      P ASS  
Sbjct: 2712 LSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTP---SDGSTPLTSILVSTLPVASSEA 2768

Query: 737  RTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSC-TRQDNPRTSSP-NRATRDNPRTS 794
             T+      TS     +  ASS   T +  ++ TS  +    P TS P N     +    
Sbjct: 2769 STVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAG 2828

Query: 795  CAQRDNLRASSPIRATQQ--DNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRD 852
                  +  S+P+  + +   +P T     +P S++++     TS        P  T   
Sbjct: 2829 TLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSI-------PVSTTPV 2881

Query: 853  RTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLR 912
             +   S     P  +S    T  E    SS   + +  +   S+P   +  +        
Sbjct: 2882 ASSEASTLSTTPVDTSIPVTTSTEG---SSSPTTAEGTSMPISTPSEVSTPLTSILVSTV 2938

Query: 913  PTQSDGPRT--SSPSRSKQSEVPWASIALRPTQGDRPQTSSP-SRPAQHDPPQSSF---- 965
            P       T  ++P  ++      A  +  PT  +   TS P S P +   P +S     
Sbjct: 2939 PVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAE--GTSMPISTPGERRTPLTSMSVST 2996

Query: 966  ---GPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPP 1013
                 ++ +  SR  + +  P   ST  +SSP      G P+++P     P
Sbjct: 2997 MPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTP 3047



 Score = 69.3 bits (168), Expect = 4e-11
 Identities = 228/1086 (20%), Positives = 370/1086 (34%), Gaps = 123/1086 (11%)

Query: 238  STLTQASSMTPHSG--PRSTTSQASPAQRDTAQAASTREIPRASSPHRITQR-DTSRASS 294
            ST   +S  TP     P ST S+ S +   T    ST  +P   +   +T + D S   +
Sbjct: 132  STEDTSSPTTPEGTDVPMSTPSEESISS--TMAFVSTAPLPSFEAYTSLTYKVDMSTPLT 189

Query: 295  TQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNP 354
            T  + S + +T + T+         P++++++  TP  +S   +T + +S    T L  P
Sbjct: 190  TSTQASSSPTTPESTT--------IPKSTNSEGSTP-LTSMPASTMKVASSEAITLLTTP 240

Query: 355  RTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRT-----------TQRENSR 403
               ST    P T     +        P +    P   S   T           ++     
Sbjct: 241  VEIST----PVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLS 296

Query: 404  TSCAQRDNPKASRT---SSPNRATRDN-PRTSCAQRDNPRASSPSR----ATRDNPTTSC 455
            T+ A  + P  + T   SSP  A   + P ++  +   P  S+P+     AT +  T S 
Sbjct: 297  TTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSI 356

Query: 456  AQRDNPRASRTSS-----PNRATRDNPRTS-CAQRDNPRASSPSR----ATRDNPTTSCA 505
               D      TS+     P  A   +  TS  ++   P  + P      A+ +  TTS  
Sbjct: 357  TPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTI 416

Query: 506  QRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTS 565
              D+     T+S       +P T  A+  +   S+P+  +   P TS      P AS  +
Sbjct: 417  PVDSKTFVTTAS---EASSSPTT--AEDTSIATSTPSEGS--TPLTSMPVSTTPVASSEA 469

Query: 566  SPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNP- 624
            S    T  + +T         +S P       PT++ ++   P  S + S          
Sbjct: 470  SNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEAS 529

Query: 625  --RTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNP 682
               T+      P  +S   ++   +P  +      P   S   T    + R   +   + 
Sbjct: 530  TLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEAST 589

Query: 683  RASSP--SRTIQQENPRTSCAQRDDPRASSPNRT-TQQENPRTSCARRDNPRASSRNRTI 739
             +++P  S T    +   S +       S P  T +++    TS +      ASS   T+
Sbjct: 590  TSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTL 649

Query: 740  QRDNPRTSCAQRDNPRASSPNRTIQQENLRTSC-TRQDNPRTSSP-NRATRDNPRTSCAQ 797
                  ++     +  A+S + T +  ++ TS  T    P TS P N     +   S   
Sbjct: 650  STTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLS 709

Query: 798  RDNLRASSPIRATQQ--DNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQ 855
               +  S+P+  + +   +P T    ++P S+ ++   P TS      L  T ++     
Sbjct: 710  TTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLL-TSSEASTLS 768

Query: 856  SFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPL-RPT 914
            +         T+S++          +S   ST    P   SP  T+  IP +  P+  P 
Sbjct: 769  TTPLDTSTHITTSTEASCSPTTTEGTSMPIST----PSEGSPLLTS--IPVSITPVTSPE 822

Query: 915  QSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQTSSPSR---PAQHDPPQSSFGPTQ-Y 970
             S    T   S S  +     S +  P +G    TS+ S    P    P  ++   T   
Sbjct: 823  ASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAI 882

Query: 971  NLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPP 1030
            +  S     +  P   ST   SSP        P ++P     P    +     P  SS  
Sbjct: 883  STLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTP-LTSMPDSTTPVVSSEA 941

Query: 1031 RYLQHDPF----PFFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFP 1086
            R L   P     P      A  S P   E   IP +        P  S+P  HT      
Sbjct: 942  RTLSATPVDTSTPVTTSTEA-TSSPTTAEGTSIPTST-PSEGTTPLTSTPVSHT------ 993

Query: 1087 FLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQDLPRASTES 1146
             L   S+A     +P      L          +  ASSPP             P A   S
Sbjct: 994  -LVANSEASTLSTTPVDSNTPLTT--------STEASSPP-------------PTAEGTS 1031

Query: 1147 LVPSMDSLHECPHIPTPV---CIGHRDAPSFSSPPRQAPEPSLFFQD-------PPGTSM 1196
            +  S  S    P    PV    +   +  + S+ P     P   +           GTSM
Sbjct: 1032 MPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSM 1091

Query: 1197 ESLAPSTDSLHGSPVLIPQVCIGHRDAPRASSPP--RHPPSDLAFLAPSPSPGSSGGSRG 1254
             +   S  S   + V +    +   +A   S+ P     P   +  A S    + G S  
Sbjct: 1092 PTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIP 1151

Query: 1255 SAPPGE 1260
            ++PP E
Sbjct: 1152 TSPPSE 1157



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 214/1050 (20%), Positives = 347/1050 (33%), Gaps = 150/1050 (14%)

Query: 276  PRASSPHRITQRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQED-----TP 330
            P  +S       DT   SST     R + T+  T+ + ST + T    S+ ED     TP
Sbjct: 89   PEMTSIESSVTSDTPGVSST-----RMTPTESRTT-SESTSDSTTLFPSSTEDTSSPTTP 142

Query: 331  RASSTQWNTPRASSPSRS---------------------TQLDNPRTSSTQQDNPQTSFP 369
              +    +TP   S S +                       +  P T+STQ     +S P
Sbjct: 143  EGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQ----ASSSP 198

Query: 370  TCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSSPNRATRDNPR 429
            T       P++   +   P  S P  T +  +S          + S   + +     +P 
Sbjct: 199  TTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPT 258

Query: 430  TSCAQRDNPRASSPSRATRDNPTT----SCAQRDNPRASRTSSPNRATRDNPRTSCAQRD 485
            T+    + P  S+ + +    P T    S     +  AS  S+   AT     TS     
Sbjct: 259  TA----EGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASS 314

Query: 486  NPRAS------SPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRAS 539
            +P  +      + +      P TS      P A+   S    T  +  T       P + 
Sbjct: 315  SPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSL 374

Query: 540  SPNRAARDNPTTSCAQRDNPRASR-TSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNP 598
                 A    T++ ++   P  +   S+   A+ +   TS    D+    +       +P
Sbjct: 375  PTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSP 434

Query: 599  TTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASS--PNRTTQQDSPRTSCARRD 656
            TT+        +  TS+P+  +   P TS      P ASS   N +T     +T      
Sbjct: 435  TTA-----EDTSIATSTPSEGS--TPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTST 487

Query: 657  DPRASSPNRTI---------QQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPR 707
            +  +S P   +         +   P TS ++   P ASS + T+      TS        
Sbjct: 488  EASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSE 547

Query: 708  ASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQEN 767
            ASS + T +  +  TS      P   S   T    N   S     +  AS+ + T    N
Sbjct: 548  ASSSSTTPEGTSIPTS-----TPSEGSTPLT----NMPVSTRLVVSSEASTTSTTPADSN 598

Query: 768  LRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSS 827
              T  T      +SS        P ++ ++R     S  +  T   +         P  S
Sbjct: 599  --TFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDS 656

Query: 828  STQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRST 887
            +T    P T+ T+  +   T        S   +   P TS     T       +S   ST
Sbjct: 657  NT----PVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTT-----LVASSEAST 707

Query: 888  QWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRP 947
                P ++S                P  +    +SSP+ +  + +P ++    P++G  P
Sbjct: 708  LSTTPVDTS---------------TPVTTSTEASSSPTTADGASMPTST----PSEGSTP 748

Query: 948  QTSSP-SRPAQHDPPQSSFGPTQYNLPSRATSSSH-NPGHQSTSRTSSPVYPAAYGAPLT 1005
             TS P S+        S+   T  +  +  T+S+  +    +T  TS P+   + G+PL 
Sbjct: 749  LTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLL 808

Query: 1006 SPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESEPPHHEPPYIPPAVCI 1065
            +  P      V I    +P AS+          P         S  P        P    
Sbjct: 809  TSIP------VSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSM--PTSTY 860

Query: 1066 GHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPV--CIGYRDAPRAS 1123
                 P  S P           +  T  A     +    P+    PV      R +P  S
Sbjct: 861  SEGRTPLTSMP-----------VSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTS 909

Query: 1124 ---SPPRQAP-EPSLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPR 1179
               S P   P E S     +P ++T  +     +L       TPV          S+P  
Sbjct: 910  EGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLS-----ATPV--------DTSTPVT 956

Query: 1180 QAPEPSLFFQDPPGTSMESLAPSTDSLHGSPVLIPQVCIGHRDAPRASSPP--RHPPSDL 1237
             + E +       GTS+ +  PS  +   +   +    + + +A   S+ P   + P   
Sbjct: 957  TSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTT 1016

Query: 1238 AFLAPSPSPGSSGGSRGSAPPGETRHNLER 1267
            +  A SP P + G S  ++ P E    L R
Sbjct: 1017 STEASSPPPTAEGTSMPTSTPSEGSTPLTR 1046



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 98/434 (22%), Positives = 158/434 (36%), Gaps = 77/434 (17%)

Query: 135  TSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGPRADSSQRAPSLL 194
            T  P+S+TP   S  +S+   T         + +    M        P + +S+R+  L 
Sbjct: 3766 TRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTM--------PMSTTSERSTLLT 3817

Query: 195  TR--SPVG--------------GDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRS 238
            T   SP+               GD +      T  G  S       +R    +S+   RS
Sbjct: 3818 TVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIR----ISITSERS 3873

Query: 239  T-LTQ--ASSMTPHSGPRSTTSQASPAQRDTA-----QAASTREIPRAS--SPHRITQRD 288
            T LT    S+  P S P ++ +   P    T        AST  IP A+  S   IT+  
Sbjct: 3874 TPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGS 3933

Query: 289  T---------SRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNT 339
            T         +  +S+  ++  A++    T   +ST+ +TP  SS+   T  +++ ++ T
Sbjct: 3934 TPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTT 3993

Query: 340  PRASSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQR 399
            P  ++ +  T +    T ST    P+T+   CT                 ++S    T  
Sbjct: 3994 PAMTTAAPLTYV----TMSTAPSTPRTTSRGCT----------------TSASTLSATST 4033

Query: 400  ENSRTSCAQRDNPKASRTSSPNRATRDN--PRTSCAQRDNPRASSPSRAT-RDNPTTSCA 456
             ++ TS   R    +S +S P+  T     P    A    P  +S S  T      T+  
Sbjct: 4034 PHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMT 4093

Query: 457  QRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTS 516
             R  P    TS P   T   P T+   + NP       +T   P T+    D  + + + 
Sbjct: 4094 TRTKPSTRTTSFPTVTTTAVP-TNTTIKSNP------TSTPTVPRTTTCFGDGCQNTASR 4146

Query: 517  SPNRATRDNPRTSC 530
              N  T D  +  C
Sbjct: 4147 CKNGGTWDGLKCQC 4160



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 157/802 (19%), Positives = 267/802 (33%), Gaps = 100/802 (12%)

Query: 239  TLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQE 298
            T +  +S++P +   ++   +SP++  T  A+    +P +++P  +   + +  S+T  +
Sbjct: 3372 TTSTEASLSPTTAEGTSIPTSSPSEGTTPLAS----MPVSTTP--VVSSEVNTLSTTPVD 3425

Query: 299  ISRASSTQQETSRASSTQEDT--PRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRT 356
             +   +T  E S + +  E T  P +++++  TP +      TP ASS + ST    P  
Sbjct: 3426 SNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEA-STLSTTPVD 3484

Query: 357  SSTQ--QDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKA 414
            +ST     +P  S PT       P +   +   P  + P  TT   +S  S        +
Sbjct: 3485 TSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDS 3544

Query: 415  SRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRD-----------------NPTTSCAQ 457
            +   + +     +P T   Q    R S+PS  +                    P+T    
Sbjct: 3545 NTFVTSSSQASSSPAT--LQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVD 3602

Query: 458  RDNPRASRTSSPNRATRDN----PRTSCAQRDNPRASSPSRATR----DNPTTSCAQRDN 509
            R  P  + T S +  T       P ++ ++   P    P   T     +  T S    D 
Sbjct: 3603 RSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDT 3662

Query: 510  PRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNR 569
                 TS+   ++   P  +      P   S         TT     +    S  S+P+ 
Sbjct: 3663 STPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEG---STLSTPSV 3719

Query: 570  ATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCA 629
             T     TS         +  + AT D+ T S +    P    T          P T   
Sbjct: 3720 VTSTPVTTSTE-------AISSSATLDSTTMSVSM---PMEISTLGTTILVSTTPVTRFP 3769

Query: 630  QRDNPRASS--PNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSP 687
            +   P   S   + +    S  +S     +   + P  T  + +   +  L       SP
Sbjct: 3770 ESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSP 3829

Query: 688  SRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTS 747
            S       P            S+P  T+ +    +  A     R S    T +R  P T+
Sbjct: 3830 SEASTLSTPPGD--------TSTPLLTSTKAGSFSIPAEVTTIRISI---TSERSTPLTT 3878

Query: 748  CAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRA---- 803
                     S P  +I       S    D   T +P+  T   P    A   ++      
Sbjct: 3879 LLVSTTLPTSFPGASI------ASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEG 3932

Query: 804  ----------SSPIRATQQDN-PRTCIQQNIPRSSSTQQDNPKTSC--------TKRDNL 844
                      S+P+ ++  D  P T    + P  +ST+ + P TS         T ++  
Sbjct: 3933 STPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFT 3992

Query: 845  RPTCTQRDRTQ--SFSFQRDNPGTSSSQCCTQKENLRPSS-PHRSTQWNNPRNSSPHRTN 901
             P  T        + S     P T+S  C T    L  +S PH ST       +    ++
Sbjct: 3993 TPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESS 4052

Query: 902  KDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDPP 961
            +     S  + PT      ++ P+ S  S           T   +P T + S P      
Sbjct: 4053 RPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPT----V 4108

Query: 962  QSSFGPTQYNLPSRATSSSHNP 983
             ++  PT   + S  TS+   P
Sbjct: 4109 TTTAVPTNTTIKSNPTSTPTVP 4130



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 156/797 (19%), Positives = 262/797 (32%), Gaps = 72/797 (9%)

Query: 42   SPSGAEVPYCDLP--RCPPAPEDPLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPT 99
            SPS    P   +P    P    +  + ST+   S  +  +    +   SP+       PT
Sbjct: 3393 SPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDS--NTLVTTSTEASSSPTIAEGTSLPT 3450

Query: 100  AAPRSRSRELEAVPYLEGLTTSLCGSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVER 159
            +     S  L  +P     TT +  S   +  +  T+  D++TP  TS+ ++    T E 
Sbjct: 3451 STTSEGSTPLSIMPLS---TTPVASS---EASTLSTTPVDTSTPVTTSSPTNSSPTTAEV 3504

Query: 160  QEEEAPSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAG 219
                  +  E +  +   P       SS+   S L+ +PV  +              +  
Sbjct: 3505 TSMPTSTAGEGSTPLTNMPVSTTPVASSEA--STLSTTPVDSNTFVTSSSQASSSPATLQ 3562

Query: 220  QHWARL----RGESGLSLERHRSTLTQASSMTPHSGP---RSTTSQASPAQRDTAQAAST 272
                R+     G S L+     ST   +S  +  S P   RST    S     T      
Sbjct: 3563 VTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEV 3622

Query: 273  REIPRASSPHRI----TQRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQED 328
              +P  S+P  +    T    S  S T  E   AS+   +TS    T      +  T E 
Sbjct: 3623 ITLPM-STPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEG 3681

Query: 329  T--PRASSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQD 386
            T  P  + ++ +TP  + P  +T++ +   S+    +  TS P  T       +  +   
Sbjct: 3682 TTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDST 3741

Query: 387  DPRASSPNRTTQRENS---RTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSP 443
                S P   +    +    T+   R  P++S  S P+  T  +  T+     +P   + 
Sbjct: 3742 TMSVSMPMEISTLGTTILVSTTPVTR-FPESSTPSIPSVYTSMSMTTASEGSSSP---TT 3797

Query: 444  SRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTS 503
               T   P ++ ++R     +   SP      +  ++ +      ++    +T+    + 
Sbjct: 3798 LEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSI 3857

Query: 504  CAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASR 563
             A+    R S TS      R  P T+         S P  +    P    +    P    
Sbjct: 3858 PAEVTTIRISITSE-----RSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDT 3912

Query: 564  TSSPNRATR-----------DNPRTSCAQRDNPRASS------PNRATRDNPTTSCAQRD 606
             S+P                  P T+      P  SS              P  +  + +
Sbjct: 3913 ASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELN 3972

Query: 607  NPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRT 666
             P  S +S+    +     T+ A       +    +T   +PRT+ +R     AS+ + T
Sbjct: 3973 TPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTT-SRGCTTSASTLSAT 4031

Query: 667  IQQENPRTSCALRDNP-----RASSPSRTIQQENPRT-SCAQRDDPRASSPNRTTQQENP 720
                 P TS ++   P      +S PS       P T   A    P  +S + TT     
Sbjct: 4032 ---STPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEA 4088

Query: 721  RTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRT 780
             T+   R  P      RT       T+    +    S+P  T       T+C       T
Sbjct: 4089 VTTMTTRTKP----STRTTSFPTVTTTAVPTNTTIKSNPTSTPTVPR-TTTCFGDGCQNT 4143

Query: 781  SS--PNRATRDNPRTSC 795
            +S   N  T D  +  C
Sbjct: 4144 ASRCKNGGTWDGLKCQC 4160


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 855

 Score = 85.9 bits (211), Expect = 4e-16
 Identities = 153/600 (25%), Positives = 211/600 (35%), Gaps = 81/600 (13%)

Query: 756  ASSPNRTIQQENLRTSCTRQDNPRTSSP--NRATRDNPRTSCAQRDNLRASSPIRATQQD 813
            A+ P    +    R++ T   NP +  P   R  R  P  + +       SSP RA+   
Sbjct: 68   ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGP---VSSPGRASGTT 124

Query: 814  NP--------RTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPG 865
             P        R   ++ + R  +T+   PK S       R T      T S +  R +  
Sbjct: 125  RPGPLGQKGLRISAEETVARGKATEA--PKRSALSAGARRDTSGPTPGTPSPAMARRSRA 182

Query: 866  TSSSQCCTQKE-NLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASF-----------PLRP 913
              +     +   + RP  P    +  +  ++S H T +  P A               R 
Sbjct: 183  AGTEVGLPRPAPSARPRPPTEGPR-KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241

Query: 914  TQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNL- 972
              S     SSP+RS  S          P+Q  +P+     RP Q  PP+    P    L 
Sbjct: 242  LSSSATPLSSPARSGPSARGTPRAPAHPSQ-PKPKGLQALRPPQVTPPRKDAAPALGPLS 300

Query: 973  --------PSRATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAP 1024
                    PS A  S   P   +T  +SS     A   PL  P PS PP    +    A 
Sbjct: 301  SSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT 360

Query: 1025 RAS-------SPPRYLQHDPFPFFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRA--SS 1075
              S       SP     H   P      +P   P    PP  PPA+ +    AP +  +S
Sbjct: 361  PPSQATTSLGSPTLQATHSFLP------SPPLSPLATPPPQAPPALALPPLQAPPSPPAS 414

Query: 1076 PPRHTQFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRAS---SPPRQAPEP 1132
            PP      P P  P+   A H  Q+P   P   P         +P  S   +PP QAP P
Sbjct: 415  PPLSPLATPSPQAPNAL-AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP-P 472

Query: 1133 SLLFQDLPRASTESLVPSMD-SLHECPHIPTPVCIGHRDAP--SFSSPPRQAPEPSLFFQ 1189
            SL    L    +    P M  S    P  P P+      AP    + PP QAP P+L   
Sbjct: 473  SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA-----APPLQLAKPPPQAP-PAL--A 524

Query: 1190 DPPGTSMESLAPSTDSLHGSPVLIPQVCIGHRDAPRASSPPRHPP---SDLAFLAPSP-- 1244
             PP   +++L     S  G     P   +    +P A+ PP+ PP   + L  + PSP  
Sbjct: 525  TPP---LQALPSPPASFPGQAPFSPSASLPM--SPLATPPPQAPPVLAAPLLQVPPSPPA 579

Query: 1245 SPGSSGGSRGSAPPGETRHNLEREEYTVLADLPPP--RRLAQRQPGPQAQCSSGGRTHSP 1302
            SP      R   P  +T  +  R    +    PPP  R  +    GP     S   T +P
Sbjct: 580  SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 639



 Score = 80.5 bits (197), Expect = 2e-14
 Identities = 167/713 (23%), Positives = 245/713 (34%), Gaps = 95/713 (13%)

Query: 587  ASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPR-ASSPNRTTQQ 645
            A+ P  A R  PT S        ASR  +  R  R  P    A+  +P   SSP R    
Sbjct: 68   ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPP----AKNTSPGPVSSPGRA--- 120

Query: 646  DSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDD 705
                 S   R  P      R   +E      A  + P+ S+ S   +++   TS      
Sbjct: 121  -----SGTTRPGPLGQKGLRISAEETVARGKAT-EAPKRSALSAGARRD---TSGPTPGT 171

Query: 706  PRASSPNRT----TQQENPRTSCARRDNPRASSRNRTI----QRDNPRTSCAQRDNPRAS 757
            P  +   R+    T+   PR + + R  P      +++    +      S A R  P A 
Sbjct: 172  PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231

Query: 758  SPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSC-AQRDNLRASSPIRATQQDNPR 816
               +     +L +S T   +P  S P+   R  PR      +   +    +R  Q   PR
Sbjct: 232  GGLQRPASRSLSSSATPLSSPARSGPS--ARGTPRAPAHPSQPKPKGLQALRPPQVTPPR 289

Query: 817  TCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKE 876
                  +   SS+    P  S   +    PT      + S + Q   P   +    +   
Sbjct: 290  KDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPP 349

Query: 877  NLR--PSSP-----HRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQ 929
            +L+  PS P       +T   +P   + H      P +     P Q+       P ++  
Sbjct: 350  SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 409

Query: 930  SEVPWASIALRPTQGDRPQT---------SSPSRPAQHDPPQSSFGPTQYNLPSRATSSS 980
            S  P AS  L P     PQ           +P  P    P Q+ F P      S   S S
Sbjct: 410  S--PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA----SPPVSPS 463

Query: 981  HNPGHQSTSRTSSP---VYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDP 1037
              P  Q+    ++P   V P+   +P  SP  + PP A        P  ++PP  L   P
Sbjct: 464  ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA-------PPPLAAPPLQLAKPP 516

Query: 1038 FPFFPEPRAPESE----PPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFL--PDT 1091
                P    P  +    PP   P   P +       +P A+ PP+       P L  P +
Sbjct: 517  PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 576

Query: 1092 SDAEHQCQSPQHEPLQLPAPVCIGYRD----APRASSPPRQAPEPSLLFQDLP-----RA 1142
              A    Q+P+  P   P     G R     AP    PP ++P  +L   DL        
Sbjct: 577  PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 636

Query: 1143 STESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPR---QAPEPSLFFQDPPGTSMESL 1199
            ST   +   DS  E     +P      DA   +  P    + P P L F+  PG  +   
Sbjct: 637  STPEELRGYDSGPEGGAAASPP----PDAELAACHPAAWSRGPAPPLAFRGAPGAPLP-W 691

Query: 1200 APSTDSLHGSPVLIPQVC-IGHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGG 1251
             P+T      P     +C I   + P +++P          L P PSPG+SGG
Sbjct: 692  PPAT-----GPGSADGLCTIYETEGPESATPAP------GALDPGPSPGTSGG 733



 Score = 55.1 bits (131), Expect = 8e-07
 Identities = 151/641 (23%), Positives = 224/641 (34%), Gaps = 103/641 (16%)

Query: 63  PLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTAAPRSRSRELEAVPYLEGLTTSL 122
           PL+    G      P     P+ GP+ SAG     P + P +  R   A P         
Sbjct: 57  PLAERAGGIGGATIP--ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPP--------- 105

Query: 123 CGSCNEDPGSDPTSSPDSAT----PDDTSNSS---SVDWDTVERQEEEAPSWDELAVMIP 175
             + N  PG  P SSP  A+    P          S +      +  EAP    L+    
Sbjct: 106 --AKNTSPG--PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAG-A 160

Query: 176 RRPREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGR-----------SAGQH--- 221
           RR   GP   +   +P++  RS   G   G  +       R           SA +H   
Sbjct: 161 RRDTSGPTPGTP--SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218

Query: 222 ----WARLRGESGLSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPR 277
                AR R  +G  L+R  S  + +SS TP S P    +++ P+ R T +A +    P+
Sbjct: 219 EPSPAARRRPSAGGGLQRPASR-SLSSSATPLSSP----ARSGPSARGTPRAPAHPSQPK 273

Query: 278 -----ASSPHRIT--QRDTSRASS--TQQEISRASSTQQETSRASSTQEDTPRASS--TQ 326
                A  P ++T  ++D + A    +   ++  S +    S+A  T   TP +SS   Q
Sbjct: 274 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQ 333

Query: 327 EDTP----------RASSTQWNTPRASSPSR-STQLDNPRTSSTQQDNPQTSF-PTCTPQ 374
             TP            S     +P A+ PS+ +T L +P   +T    P     P  TP 
Sbjct: 334 LATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP 393

Query: 375 RENPRT----PCVQQDDPRASSPNRTTQRENSRTSCAQR----DNPKASRTSSPNRATRD 426
            + P      P      P AS P       + +   A        P +   S P +A   
Sbjct: 394 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 453

Query: 427 NPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDN 486
            P +      +P A+ PS+A             +P AS   SP+        T   Q   
Sbjct: 454 PPASPPV---SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS-------ATPPPQAPP 503

Query: 487 PRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRD-NPRASSPNRAA 545
           P A+ P +  +  P    A    P  +  S P       P +  A    +P A+ P +A 
Sbjct: 504 PLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 563

Query: 546 RDNPTTSCAQRDNPRASRT-SSPNRATRDNPRTSCAQRDNPR-----ASSPNRATRDNPT 599
                       +P AS T  +P R     P TS +    PR     A  P      +P+
Sbjct: 564 PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS---GPRLTLALAPGPPPPPSRSPS 620

Query: 600 TSCAQRD--NPRASRTSSPN--RATRDNPRTSCAQRDNPRA 636
           ++ +  D     +S TS+P   R     P    A    P A
Sbjct: 621 STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDA 661



 Score = 36.2 bits (82), Expect = 0.39
 Identities = 101/492 (20%), Positives = 156/492 (31%), Gaps = 57/492 (11%)

Query: 29  PEEAHGARYQELRSPSGAEVPYCDLPRCPP-------APEDPLSASTSGCQSVVDPGLRP 81
           P    G +    RS S +  P     R  P       AP  P      G Q++  P + P
Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 287

Query: 82  -----GPKRGPSPSAGLPEEGPTAAPRSRS-RELEAVPYLEGLTTSLC-------GSCNE 128
                 P  GP  S+ L    P+AA +S++   L A P+   LT  L         S + 
Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSA 347

Query: 129 DPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGPRADSSQ 188
            P      SP +  P     ++S+   T++      PS           P   P A    
Sbjct: 348 PPSLQTLPSPPATPPSQA--TTSLGSPTLQATHSFLPS-----------PPLSPLATPPP 394

Query: 189 RAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRSTLTQASS--- 245
           +AP  L   P+    +             + Q        + L++   ++  +   S   
Sbjct: 395 QAPPALALPPLQAPPSPPASPPLSPLATPSPQ------APNALAVHLLQAPFSPPPSPPV 448

Query: 246 ---MTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEISRA 302
               +P + P  + S   P+Q   + AA   ++P   SP        S     Q     A
Sbjct: 449 QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP--PSPPASPPMSPSATPPPQAPPPLA 506

Query: 303 SSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQD 362
           +   Q    A    +  P  ++       +    +      SPS S  + +P  +   Q 
Sbjct: 507 APPLQ---LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM-SPLATPPPQA 562

Query: 363 NPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSSPNR 422
            P  + P        P +P +Q    R  +P   T     R + A    P    + SP+ 
Sbjct: 563 PPVLAAPLLQVPPSPPASPTLQA-PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS- 620

Query: 423 ATRDNPRTSCAQRDNPRASSPS--RATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTS 480
           +T   P    A   +   S+P   R     P    A    P A   +    A    P   
Sbjct: 621 STLSGP--DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPP 678

Query: 481 CAQRDNPRASSP 492
            A R  P A  P
Sbjct: 679 LAFRGAPGAPLP 690



 Score = 32.3 bits (72), Expect = 5.7
 Identities = 88/342 (25%), Positives = 121/342 (35%), Gaps = 40/342 (11%)

Query: 1398 TSARTPERELRTQRPLESGQAGPRQPLGVWQSQEEPPGS-QGPHRHLERSWSSQEGGLGP 1456
            TS+R P       RP  SG+ G R P     ++   PG    P R    S +++ G LG 
Sbjct: 85   TSSRNP-----ASRPPASGR-GERAP----PAKNTSPGPVSSPGR---ASGTTRPGPLGQ 131

Query: 1457 GGWWGCGEPSLGAAKAPEGAW-----GGTSREYK-ESWGQPEAWEEKPTHELPRELGKRS 1510
             G     E ++   KA E         G  R+    + G P     + +     E+G   
Sbjct: 132  KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 191

Query: 1511 PLTS----PPENWGGPAESSQSWHSGTPTAVGWGAEGACPYPRGSERRP-----ELDWRD 1561
            P  S    PP      + SS S HS T  +    A    P   G  +RP           
Sbjct: 192  PAPSARPRPPTEGPRKSVSSASEHSTTEPSP---AARRRPSAGGGLQRPASRSLSSSATP 248

Query: 1562 LLGLLRA-PGEGVWARVPSLDWEGLLELLQA-RLPRKDPAGHRDDLARALGPELGPPGTN 1619
            L    R+ P      R P+   +   + LQA R P+  P   R D A ALGP    P   
Sbjct: 249  LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP--RKDAAPALGPLSSSPLAT 306

Query: 1620 DVPEQESHSQPEGWAEATPVNGHSPALQSQSPVQLPSPACTSTQWPKIK-VTRGPATATL 1678
              P     SQ      ATP   HS +L  Q    LP    + +  P ++ +   PAT   
Sbjct: 307  PSPSAALQSQAPPTLPATP---HSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS 363

Query: 1679 AGLEQTGPLGSRSTAKGPSLPELQFQPEEPEESEPSRGQDPL 1720
                  G    ++T      P L      P ++ P+    PL
Sbjct: 364  QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL 405


>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
            sapiens]
          Length = 1393

 Score = 85.1 bits (209), Expect = 7e-16
 Identities = 205/1043 (19%), Positives = 345/1043 (33%), Gaps = 125/1043 (11%)

Query: 126  CNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGPRAD 185
            CN    S PT  P       T NS ++D  +     E  P+ +E               +
Sbjct: 87   CNTTRHSKPTDKP-------TGNSKTIDHKSSTDNHEAPPTSEE---------------N 124

Query: 186  SSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERH---RSTLTQ 242
            SS +    + R+    D A    + T     SAG+       +S ++  +    +ST+T+
Sbjct: 125  SSNQGKDPMIRNQRSVDPA----DSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTVTR 180

Query: 243  ASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASST-QQEISR 301
             S  T     +S +         T    ST      +S H      T + S++  ++I+ 
Sbjct: 181  KSDKTGRPLEKSMS---------TLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITA 231

Query: 302  ASSTQQETSRASSTQEDTPRASSTQEDTPRA-------SSTQWNTPRASSPSRSTQLDNP 354
            AS T  +T+        TP  S   ED+          + T  N     S +  TQ    
Sbjct: 232  ASKTTYKTT-------GTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAE 284

Query: 355  RTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKA 414
             T    +   + + P+     EN      +      + P    +R  +  +      P  
Sbjct: 285  PTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPIENRERTANENTAPFPAGPTE 344

Query: 415  SRTSSPNRATRDNPR--TSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRA 472
            +R  + N  T   P   T   +R     ++PS A    PT    +  N   + T SP   
Sbjct: 345  NREMTANENTTLFPAEPTEHGERTANENTTPSPA---EPTEHGERTAN--ENTTPSPAEP 399

Query: 473  TRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDN--PRASRTSSPNRATRDNPRTSC 530
            T    RT  A  ++   SS + +T     T  A  +     A  T +  R   +N   S 
Sbjct: 400  TEHGERTPFA--NDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSP 457

Query: 531  AQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTS-SPNRATRDNPRTSCAQRDNPRASS 589
            A     R ++ N     +P      R+     +T+ SP   T +  RT  A      +S+
Sbjct: 458  AGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSA 517

Query: 590  -----------PNRATRDNPTTSCAQRDNPRASRTS-SPNRATRDNPRTSCA-QRDNPRA 636
                        N  T  +P      R+     +T+ SP   T +  RT  A ++  P  
Sbjct: 518  EPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSL 577

Query: 637  SSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSR-TIQQEN 695
            + P    Q    RT  A      +S+     ++  P  +     +P   + +R     EN
Sbjct: 578  AEPTENGQ----RTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANEN 633

Query: 696  PRTSCAQRDDPRASSPNRTTQ--QENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDN 753
               S A   + R  + N  T      P  +  R  N + +S       +  RT  A   N
Sbjct: 634  TTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFA---N 690

Query: 754  PRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQD 813
             + +S +    +   RT    ++   T SP   T +  RT+  +      ++P  A   +
Sbjct: 691  EKTTSSSAEPTEHGERTPLANENT--TLSPAEPTENRERTANEK------TTPFPAEPTE 742

Query: 814  NPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCT 873
            N      +N   S +   +N   +    +   P+  +       +   +   TSSS   T
Sbjct: 743  NRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPT 802

Query: 874  QKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVP 933
            +     P +   +T        +  RT  +     FP  PT++      S +  K +  P
Sbjct: 803  EHAERTPLANENTTSSPAEPTENRERTANE-KTTQFPAEPTEN----RESTANEKTTPFP 857

Query: 934  WASIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSS 993
                  R    +   T SP+ P +H+             P+  T +       +   T S
Sbjct: 858  AEPTENREWTANENTTLSPAEPTEHEEMTPLANEKTTLSPAEPTENGERTPFTNEKTTPS 917

Query: 994  PVYPAAYGA------PLTSPEPSQPP--CAVCIGHRDAPRASSPPRY----LQHDPFPFF 1041
               P  +G        +T+P  ++P          +  P  + P  +    +  D  P  
Sbjct: 918  SAEPTEHGERTPLANEITTPSRAEPTEHGERIANEKATPSPAKPTEHGETTVNEDTTPSS 977

Query: 1042 PEP-RAPESEPPHHEPPYIPPAVCIGH-------RDAPRASSPPRHTQFDPF---PFLPD 1090
             EP    E  P  +E     P     H       +  P  + P  H +  P      +P 
Sbjct: 978  AEPTENGERTPLANENTTTSPTESTEHGERTANEKTTPSPAEPTEHGERTPSANEKTIPS 1037

Query: 1091 -TSDAEHQCQSPQHEPLQLPAPV 1112
                 EH+  +P       P+PV
Sbjct: 1038 PAKPTEHEEMTPSANENTTPSPV 1060



 Score = 82.8 bits (203), Expect = 4e-15
 Identities = 160/798 (20%), Positives = 265/798 (33%), Gaps = 109/798 (13%)

Query: 254  STTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEISRASSTQQETSRAS 313
            +T S A P +    + A+    P  + P    +R       T    S A ST+       
Sbjct: 373  TTPSPAEPTEHGE-RTANENTTPSPAEPTEHGERTPFANDKTTS--SSAESTEHGERTPL 429

Query: 314  STQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQTSFPTCTP 373
            + +  TP  +   E+  R ++    TP  + P+     +N  T++ ++       PT   
Sbjct: 430  ANENTTPSPAEPTENRERTANEN-TTPSPAGPT-----ENRETTANEKTTLSPVEPT--- 480

Query: 374  QRENPRTPCVQQDDPRASSPNRTTQR---ENSRTSCAQRDNPKASRTSSPNRATRDNPRT 430
              EN  T   ++  P  + P    QR    N +T            TSS    T    RT
Sbjct: 481  --ENRETTANEKTTPSPAEPTENGQRTPFANEKT------------TSSSAEPTEHGERT 526

Query: 431  SCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCA-QRDNPRA 489
              A  +     SP+  T +   T+           T SP   T +  RT  A ++  P  
Sbjct: 527  PLANENT--TPSPAEPTENRERTA-------NEKTTPSPAEPTENGDRTPLANEKTTPSL 577

Query: 490  SSPSRATRDNP-----TTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRA 544
            + P+   +  P     TTS +        RT   N  T  +P      R+        R 
Sbjct: 578  AEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRE--------RT 629

Query: 545  ARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQ 604
            A +N T S A    P  +R  + N  T   P      R+          T +  TTS   
Sbjct: 630  ANENTTPSPA---GPTENREMTANEKTTLFPAEPTENRER---------TANEKTTSSPA 677

Query: 605  RDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPN 664
                   RT   N  T  +        +    ++ N T     P T    R     ++P 
Sbjct: 678  EPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAEP-TENRERTANEKTTPF 736

Query: 665  RTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCA-QRDDPRASSP---NRTTQQENP 720
                 EN   +      P  + P+    +   RT  A ++  P  + P    + T   N 
Sbjct: 737  PAEPTENRERTANENTTPSPAQPT----ENGDRTPLANEKTTPSLAEPTENGKRTPFANE 792

Query: 721  RTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQ------ENLRTSCTR 774
            +T+ +  + P   +    +  +N  +S A+    R  + N    Q      EN  ++   
Sbjct: 793  KTTSSSAE-PTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANE 851

Query: 775  QDNPRTSSP--NRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQD 832
            +  P  + P  NR    N  T+          SP   T+ +       +    S +   +
Sbjct: 852  KTTPFPAEPTENREWTANENTTL---------SPAEPTEHEEMTPLANEKTTLSPAEPTE 902

Query: 833  NPKTSCTKRDNLRPTCTQ----RDRT----QSFSFQRDNPGTSSSQCCTQKENLRPSSP- 883
            N + +    +   P+  +     +RT    +  +  R  P     +   +K    P+ P 
Sbjct: 903  NGERTPFTNEKTTPSSAEPTEHGERTPLANEITTPSRAEPTEHGERIANEKATPSPAKPT 962

Query: 884  -HRSTQWN---NPRNSSPHRTNKDIPWA--SFPLRPTQS--DGPRTSSPSRSKQSEVPWA 935
             H  T  N    P ++ P    +  P A  +    PT+S   G RT++   +     P  
Sbjct: 963  EHGETTVNEDTTPSSAEPTENGERTPLANENTTTSPTESTEHGERTANEKTTPSPAEPTE 1022

Query: 936  SIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPV 995
                 P+  ++    SP++P +H+    S        P + T         +   T SP 
Sbjct: 1023 HGERTPSANEK-TIPSPAKPTEHEEMTPSANENTTPSPVKPTEHGEKTTLANEKITLSPE 1081

Query: 996  YPAAYGAPLTSPEPSQPP 1013
             P  +GA  TS      P
Sbjct: 1082 GPTEHGAKTTSANEKITP 1099



 Score = 69.3 bits (168), Expect = 4e-11
 Identities = 171/888 (19%), Positives = 300/888 (33%), Gaps = 118/888 (13%)

Query: 11   EHFEANILTQNRCQNCFHPEEAHGARY-QELRSPSGAEVPYCDLPRCPPAPEDPLSASTS 69
            EH E     +N   +   P E HG R   E  +PS AE P     R P A +   S+S  
Sbjct: 363  EHGERTA-NENTTPSPAEPTE-HGERTANENTTPSPAE-PTEHGERTPFANDKTTSSSAE 419

Query: 70   GCQS-----VVDPGLRPGPKRGPSPSAGLPEEGPTAAPRSRSRELEAVPYLEGLTTSLCG 124
              +      + +    P P            E  T +P   +   E     +   + +  
Sbjct: 420  STEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEP 479

Query: 125  SCNEDPGSDPTSSPDSATPDDTSN-----SSSVDWDTVERQE--EEAPSWDELAVMIPRR 177
            + N +  ++  ++P  A P +        +      + E  E  E  P  +E     P  
Sbjct: 480  TENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAE 539

Query: 178  PREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHR 237
            P E     ++++     T SP          E T  G R+             L+ E+  
Sbjct: 540  PTENRERTANEKT----TPSPA---------EPTENGDRTP------------LANEKTT 574

Query: 238  STL---TQASSMTPHSGPRSTTSQASPAQ-RDTAQAASTREIPRASSPHRITQRDTSRAS 293
             +L   T+    TP +  ++T+S A P +  +    A+    P  + P       T    
Sbjct: 575  PSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEP-------TENRE 627

Query: 294  STQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDN 353
             T  E +  S      +R  +  E T    +   +    ++ +  T   + P+ + Q   
Sbjct: 628  RTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQ--- 684

Query: 354  PRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQD---DPRASSPNRTTQRENSRTSCAQRD 410
                 T   N +T+  +  P     RTP   ++    P   + NR        T      
Sbjct: 685  ----RTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAEPTENRERTANEKTTPFPAEP 740

Query: 411  NPKASRTS------SPNRATRDNPRTSCA-QRDNPRASSPSRATRDNP-----TTSCAQR 458
                 RT+      SP + T +  RT  A ++  P  + P+   +  P     TTS +  
Sbjct: 741  TENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAE 800

Query: 459  DNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTS-- 516
                A RT   N  T  +P    A+    R  + +  T   P      R++    +T+  
Sbjct: 801  PTEHAERTPLANENTTSSP----AEPTENRERTANEKTTQFPAEPTENRESTANEKTTPF 856

Query: 517  ----SPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATR 572
                + NR    N  T+ +  +          A +  T S A+       RT   N  T 
Sbjct: 857  PAEPTENREWTANENTTLSPAEPTEHEEMTPLANEKTTLSPAE-PTENGERTPFTNEKTT 915

Query: 573  DNPR--TSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQ 630
             +    T   +R  P A+     +R  PT    +  N +A  T SP + T ++  T+  +
Sbjct: 916  PSSAEPTEHGER-TPLANEITTPSRAEPTEHGERIANEKA--TPSPAKPT-EHGETTVNE 971

Query: 631  RDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRT 690
               P ++ P     ++  RT  A  +    ++ + T   E+   +   +  P  + P+  
Sbjct: 972  DTTPSSAEPT----ENGERTPLANEN----TTTSPTESTEHGERTANEKTTPSPAEPT-- 1021

Query: 691  IQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNP---RASSRNRTIQRDNPRTS 747
              +   RT  A  ++    SP + T+ E    S      P   + +         N + +
Sbjct: 1022 --EHGERTPSA--NEKTIPSPAKPTEHEEMTPSANENTTPSPVKPTEHGEKTTLANEKIT 1077

Query: 748  CAQRDNPRASSPNRTIQQENLRTSCTR--QDNPRTSSPNRATRDNPRTSCAQRD-----N 800
             +  + P       T   E +  S  +  +   RT+SPN     +   S   RD     N
Sbjct: 1078 LSP-EGPTEHGAKTTSANEKITPSLAKPTEHGERTTSPNDKITSSAAESTEHRDRATSAN 1136

Query: 801  LRASSPIRATQQDNPRTCIQQNIPR--SSSTQQDNPKTSCTKRDNLRP 846
            +   +P    +     T   + + +    ST+     TS T++    P
Sbjct: 1137 VITPAPAEPIKHAKRTTLAHEKMTQVTEKSTEHPEKTTSTTEKTTRTP 1184



 Score = 48.9 bits (115), Expect = 6e-05
 Identities = 92/484 (19%), Positives = 161/484 (33%), Gaps = 62/484 (12%)

Query: 88   SPSAGLPEEGPTAAPRSRSRELEAV--PYLEGLTTSLCGSCNEDPGSDPTSSPDSATPDD 145
            +PS   P E     P +  +   ++  P   G  T           ++PT   +  TP  
Sbjct: 753  TPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAER-TPLA 811

Query: 146  TSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAG 205
              N++S   +  E +E  A   +E     P  P E   + ++++            +   
Sbjct: 812  NENTTSSPAEPTENRERTA---NEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTA 868

Query: 206  QKKEDTGGGGRSAGQHWARLRGESGLSLERHRSTL-----TQASSMTPHSGPRSTTSQAS 260
               E+T        +H      E    L   ++TL     T+    TP +  ++T S A 
Sbjct: 869  N--ENTTLSPAEPTEH------EEMTPLANEKTTLSPAEPTENGERTPFTNEKTTPSSAE 920

Query: 261  PAQR-DTAQAASTREIPRASSPHRITQRDTSRAS--STQQEISRASSTQQETSRASSTQ- 316
            P +  +    A+    P  + P    +R  +  +  S  +      +T  E +  SS + 
Sbjct: 921  PTEHGERTPLANEITTPSRAEPTEHGERIANEKATPSPAKPTEHGETTVNEDTTPSSAEP 980

Query: 317  ----EDTPRASSTQEDTPRASSTQW----NTPRASSPSRSTQLDNPRTSSTQQDNPQTSF 368
                E TP A+     +P  S+       N     SP+  T+      S+ ++  P  + 
Sbjct: 981  TENGERTPLANENTTTSPTESTEHGERTANEKTTPSPAEPTEHGERTPSANEKTIPSPAK 1040

Query: 369  PT----CTPQRENPRTPCVQQDDPRAS-----------SPNRTTQRENSRTSCAQRDNPK 413
            PT     TP      TP   +                 SP   T+     TS  ++  P 
Sbjct: 1041 PTEHEEMTPSANENTTPSPVKPTEHGEKTTLANEKITLSPEGPTEHGAKTTSANEKITPS 1100

Query: 414  AS-------RTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRT 466
             +       RT+SPN     +   S   RD        RAT  N  T         A RT
Sbjct: 1101 LAKPTEHGERTTSPNDKITSSAAESTEHRD--------RATSANVITPAPAEPIKHAKRT 1152

Query: 467  S-SPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDN 525
            + +  + T+   +++         +  +  T + PT    +    +   T  P + T + 
Sbjct: 1153 TLAHEKMTQVTEKSTEHPEKTTSTTEKTTRTPEKPTLYSEKTICTKGKNTPVPEKPTENL 1212

Query: 526  PRTS 529
              T+
Sbjct: 1213 GNTT 1216



 Score = 39.7 bits (91), Expect = 0.035
 Identities = 89/416 (21%), Positives = 142/416 (34%), Gaps = 35/416 (8%)

Query: 1346 QSSPAPSRQVTMLPAKQAELTRRSQAE--PPHPWSPEKRPE--GDRQLQGSPLPPRTSAR 1401
            + +P  +   T  PA+  E   R+  E   P P  P +  E   + +   SP+ P  +  
Sbjct: 425  ERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRE 484

Query: 1402 TPERELRTQRPLESGQAGPRQPLGVWQSQEEPPGSQGPHRHLERSWSSQEGGLGPGGWWG 1461
            T   E  T  P E  + G R P   + +++    S  P  H ER+  + E          
Sbjct: 485  TTANEKTTPSPAEPTENGQRTP---FANEKTTSSSAEPTEHGERTPLANENTTP-----S 536

Query: 1462 CGEPSLGAAKAPEGAWGGTSREYKESWGQPEAWEEKPTHEL--PRELGKRSPLTSPPENW 1519
              EP+    +        +  E  E+  +     EK T  L  P E G+R+P  +  E  
Sbjct: 537  PAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFAN--EKT 594

Query: 1520 GGPAESSQSWHSGTPTAVGWGAEGACPYPRGSERRPELDWRDLLGLLRAPGEGVWARVPS 1579
               +         TP A     E   P P       E    +      +P      R  +
Sbjct: 595  TSSSAEPTEHEERTPLA----NENTTPSPAEPTENRERTANE--NTTPSPAGPTENREMT 648

Query: 1580 LDWEGLLELLQARLPRKDPAGHRDDLARALGPELG--PPGTNDVPEQESHSQPEGWAEAT 1637
             + +  L   +    R+  A  +   + A   E G   P  N+     S ++P    E T
Sbjct: 649  ANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANE-KTTSSSAEPTEHGERT 707

Query: 1638 PVNGHSPALQSQSPVQLPSPACT--STQWPKIKVTRGPATATLAGLEQTGPLGSRSTAKG 1695
            P+   +  L    P +         +T +P         TA     E T P  ++ T  G
Sbjct: 708  PLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRERTAN----ENTTPSPAQPTENG 763

Query: 1696 PSLPELQFQPEEPEESEPSRG--QDPLTDQKQADSADKRPAEGKAGSPLKGRLVTS 1749
               P L  +   P  +EP+    + P  ++K   S+   P E    +PL     TS
Sbjct: 764  DRTP-LANEKTTPSLAEPTENGKRTPFANEK-TTSSSAEPTEHAERTPLANENTTS 817


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 242/1192 (20%), Positives = 385/1192 (32%), Gaps = 140/1192 (11%)

Query: 58   PAPEDPLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTAAPRSRSRELEAVPYLEG 117
            P+ +D   A  +   + V+P          + S G P   PT    +RS     V   E 
Sbjct: 268  PSSKDTRPAPPTTTSAFVEPS---------TTSHGSPSSIPTTHISARSTTSGLV---EE 315

Query: 118  LTTSLCGSCNEDPGSDPTSS-PDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPR 176
             TT      +  PGS  T   P+S T       S+    +       APS     V    
Sbjct: 316  STTY-----HSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALV---- 366

Query: 177  RPREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERH 236
               E P +  S    +  T  P     +G+ +E T             L   S  S+   
Sbjct: 367  ---EEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLG 423

Query: 237  RSTLTQASS--MTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASS 294
             ST +  SS  M   + P STT+    ++R T   +S R      SP   T    S  S+
Sbjct: 424  ESTTSPISSGSMETTALPGSTTTPGL-SERSTTFHSSPRSPATTLSPASTTSSGVSEEST 482

Query: 295  TQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNP 354
            T +  SR  ST       S+T     R S+T   +P ++ T       +    ST    P
Sbjct: 483  TSR--SRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDT-------TLLPASTTTSGP 533

Query: 355  RTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKA 414
               ST   +   S  T                   A SP  TT     + S     NP +
Sbjct: 534  SQESTTSHSSSGSTDT-------------------ALSPGSTTALSFGQESTTFHSNPGS 574

Query: 415  SRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATR 474
            + T+    +T  +     + R +    SP        +TS   +    A +T   +  T 
Sbjct: 575  THTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTT 634

Query: 475  DNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRD 534
             +P  S A      +++  R+    PTT       P +S TS  +  +     +  A   
Sbjct: 635  PSP-PSTATAPVEESTTYHRSPGSTPTTHF-----PASSTTSGHSEKSTIFHSSPDASGT 688

Query: 535  NPRASSPNRAARDNPTTSCAQRDNPRASR-TSSPNRATRDN-PRTSCAQRDNPRASSPNR 592
             P ++    + R   TTS   R +P ++  T+ P   T       S     +PR  SP  
Sbjct: 689  TPSSAHSTTSGRGESTTS---RISPGSTEITTLPGSTTTPGLSEASTTFYSSPR--SPTT 743

Query: 593  ATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSC 652
                   TS    +    SR+   +  +  +P ++          S   TT   S R S 
Sbjct: 744  TLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTP-----GLSEESTTVYSSSRGST 798

Query: 653  ARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPN 712
                 P   S   ++  E P T      + R +S   T+  E+  TS    +        
Sbjct: 799  ETTVFPH--STTTSVHGEEPTTF-----HSRPASTHTTLFTEDSTTSGLTEESTAFPGSP 851

Query: 713  RTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSC 772
             +TQ   P           A+     +  ++     +        SP R+     +  S 
Sbjct: 852  ASTQTGLP-----------ATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGEST 900

Query: 773  TRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQD 832
              + +P ++            S +++     +SP       +P T     +   SST   
Sbjct: 901  PSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHS 960

Query: 833  NPKTSCTKR--DNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWN 890
             P ++ T    D+   +   ++ T S S Q     T S    T     + S+   S+  +
Sbjct: 961  QPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGD 1020

Query: 891  NPRNSSPHRT-NKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQT 949
                  P  T    +  AS P   +      T +P+ S  + +   S   +        T
Sbjct: 1021 TETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTT 1080

Query: 950  SSP----SRPAQ-----HDPPQSSFGPTQYNLPSRAT---SSSHNPGHQSTSRTSSPVYP 997
             SP    + P +     H  P S+  PT +   S  T   S      H S   T + ++P
Sbjct: 1081 PSPPGTTAAPVEVSTTYHSRPSST--PTTHFSASSTTLGRSEESTTVHSSPGATGTALFP 1138

Query: 998  AAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESEPPHHEPP 1057
                  +   EP+  P +       A   S+    L      F+  PR+P++        
Sbjct: 1139 TRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTT------- 1191

Query: 1058 YIPPAVCIG---HRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCI 1114
             + PA         ++  + S P  T    FP          +  +    P      +  
Sbjct: 1192 -LSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTL-- 1248

Query: 1115 GYRDAPRASSPPRQAPEPSLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIG----HRD 1170
                +P +++     PE S  F   P ++  +L+P   +        TPV       H  
Sbjct: 1249 ----SPGSTTASSLGPE-STTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTT 1303

Query: 1171 APSFSSPPRQA--------PEPSLFFQDPPGTSMESLAPSTDSLHGSPVLIP 1214
                 S  RQ         P        PP T+   +  ST S HGSP   P
Sbjct: 1304 LSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTS-HGSPSSTP 1354



 Score = 77.4 bits (189), Expect = 2e-13
 Identities = 259/1275 (20%), Positives = 432/1275 (33%), Gaps = 161/1275 (12%)

Query: 90   SAGLPEEGPTAAPRSRSRELEAVP---YLEGLTTSLCGSCNEDPGSDPTSSPDSAT---- 142
            S+G+ EE  T+  R  S    A P    + GL+     S +    +D T SP S T    
Sbjct: 144  SSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSL 203

Query: 143  -------------------PDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGPR 183
                               PD+T+ S  ++          +P           R  E   
Sbjct: 204  GPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTT 263

Query: 184  ADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQ-HWARLRGESGLSLERHRSTLTQ 242
              S   +       P    A  +    + G   S    H +     SGL  E        
Sbjct: 264  FHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEE-------- 315

Query: 243  ASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEISRA 302
              S T HS P ST +   P    T+          +S+ H I+   ++ ++  ++  S  
Sbjct: 316  --STTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYH 373

Query: 303  SSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQ---LDNPRTSST 359
            SS     S A++   D+   S   E++  + S+Q  T     P+RST    L    TS  
Sbjct: 374  SS---PGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPI 430

Query: 360  QQDNPQTSF---PTCTPQ--------RENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQ 408
               + +T+     T TP           +PR+P          SP  TT    S  S   
Sbjct: 431  SSGSMETTALPGSTTTPGLSERSTTFHSSPRSPAT------TLSPASTTSSGVSEESTTS 484

Query: 409  RDNPKASRTSS-PNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTS 467
            R  P ++ T++ P+  T   P  S       R S+ S ++  +  T+      P ++ TS
Sbjct: 485  RSRPGSTHTTAFPDSTT--TPGLS-------RHSTTSHSSPGSTDTTLL----PASTTTS 531

Query: 468  SPNRATRDNPRTSCAQRDNPRASSPSRATR-DNPTTSCAQRDNPRASRTSSPNRATRDNP 526
             P   ++++  +  +      A SP   T       S     NP ++ T+    +T  + 
Sbjct: 532  GP---SQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSG 588

Query: 527  RTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPR 586
                + R +    SP        +TS   +    A +T   +  T  +P  S A      
Sbjct: 589  IVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSP-PSTATAPVEE 647

Query: 587  ASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQD 646
            +++ +R+    PTT       P +S TS  +  +     +  A    P ++    + + +
Sbjct: 648  STTYHRSPGSTPTTHF-----PASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGE 702

Query: 647  SPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRT-SCAQRDD 705
            S  +  +       + P  T        S     +PR  SP+ T+   +  +    +   
Sbjct: 703  STTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPR--SPTTTLSPASMTSLGVGEEST 760

Query: 706  PRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQ 765
               S P  T    +P    A    P  S  + T+       S ++        P+ T   
Sbjct: 761  TSRSQPGSTHSTVSP----ASTTTPGLSEESTTVY------SSSRGSTETTVFPHSTTTS 810

Query: 766  ENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPR 825
             +     T    P ++     T D+  +   +       SP  +TQ   P T    ++  
Sbjct: 811  VHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSP-ASTQTGLPATLTTADLGE 869

Query: 826  SSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHR 885
             S+T   +  ++ TK    R T                  TS     +    L PSS   
Sbjct: 870  ESTTFPSSSGSTGTKLSPARST------------------TSGLVGESTPSRLSPSSTET 911

Query: 886  STQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSR-SKQSEVPWASIALRPTQG 944
            +T   +P  ++P  + K   + + P  P  +  P T++ S  S++S    +      T  
Sbjct: 912  TTLPGSP--TTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTA 969

Query: 945  DRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAP- 1003
                T++     +     SS G T+  L   +T++S + G QST+  SSP        P 
Sbjct: 970  FPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTAS-SLGQQSTTFHSSPGDTETTLLPD 1028

Query: 1004 --LTS--PEPSQPP-CAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESEPPHHEPPY 1058
              +TS   E S P   +    H     ASS    LQ +   F   P + ++ P    PP 
Sbjct: 1029 DTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTP---SPP- 1084

Query: 1059 IPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRD 1118
                   G   AP   S   H++    P    ++ +    +S +   +   +P   G   
Sbjct: 1085 -------GTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVH-SSPGATGTAL 1136

Query: 1119 APRASSPPRQAPEPSLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPP 1178
             P  S+      EP+     +   STE+           P   T   +  +    +SSP 
Sbjct: 1137 FPTRSATSVLVGEPTT--SPISSGSTETTA--------LPGSTTTAGLSEKSTTFYSSP- 1185

Query: 1179 RQAPEPSLFFQDPPGTSMESLAPSTDSLHGSPVLIPQVCI-GHRDAPRAS--SPPRH--P 1233
             ++P+ +L    P  T+   ++  + + H  P         G    P  S  S   H  P
Sbjct: 1186 -RSPDTTL---SPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSP 1241

Query: 1234 PSDLAFLAPSPSPGSSGGSRGS---APPGETRHNLEREEYTVLADLPPPRRLAQRQPGPQ 1290
             S    L+P  +  SS G   +   + PG T   L  +  T    L     +      P 
Sbjct: 1242 GSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPH 1301

Query: 1291 AQCSSGGRTHSPGRA 1305
               S  G T   G +
Sbjct: 1302 TTLSPAGSTTRQGES 1316



 Score = 74.7 bits (182), Expect = 1e-12
 Identities = 243/1234 (19%), Positives = 402/1234 (32%), Gaps = 156/1234 (12%)

Query: 229  SGLSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRD 288
            S +S     +T    S+  P    +STT  +SP   DT        +P + +   +++  
Sbjct: 98   SPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTT------HLPASMTSSGVSEES 151

Query: 289  T---SRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSP 345
            T   SR  ST       S+T    S+ S+    +P  + T   T    ST   T  +  P
Sbjct: 152  TTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDT---TLSPGST---TASSLGP 205

Query: 346  SRSTQLDNPRTSSTQ--QDNPQTS--FPTCTPQRENPRTPCVQQDDPRASSPNRTTQREN 401
              +T    P ++ T    DN   S       P   + R+P          SP  +T R+ 
Sbjct: 206  EYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSP------HTTLSPAGSTTRQG 259

Query: 402  SRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNP 461
              T+     + K +R + P   T      S     +P +   +  +  + T+   +    
Sbjct: 260  ESTTFHSWPSSKDTRPAPPT-TTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTT 318

Query: 462  RASRTSSPNRATRDNPRTSCAQRDNPRA--SSPSRATRDNPTTSCAQRDNPRASRTSSPN 519
              S   S          T+  + +      SS +      P+T+ A  + P +  +S  +
Sbjct: 319  YHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGS 378

Query: 520  RATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSC 579
             AT   P +S         S+ + +++D   T       P  S TS     +  +P +S 
Sbjct: 379  TATTHFPDSSTTS-GRSEESTASHSSQDATGTIVL----PARSTTSVLLGESTTSPISSG 433

Query: 580  AQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSP 639
            +        S         +T+     +PR+  T+    +T  +  +  +     R  S 
Sbjct: 434  SMETTALPGSTTTPGLSERSTTF--HSSPRSPATTLSPASTTSSGVSEESTTSRSRPGST 491

Query: 640  NRTTQQDSPRT-SCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRT 698
            + T   DS  T   +R      SSP  T        +  L  +   S PS    QE+  +
Sbjct: 492  HTTAFPDSTTTPGLSRHSTTSHSSPGST-------DTTLLPASTTTSGPS----QESTTS 540

Query: 699  SCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTS----CAQRDNP 754
              +      A SP  TT     + S     NP   S + T+  D+  +S     + R + 
Sbjct: 541  HSSSGSTDTALSPGSTTALSFGQESTTFHSNP--GSTHTTLFPDSTTSSGIVEASTRVHS 598

Query: 755  RASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDN 814
               SP  T+   +  +   + ++    +   +T   P         +  S+    +    
Sbjct: 599  STGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGST 658

Query: 815  PRTCIQQNIPRSSSTQ---------QDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDN-- 863
            P T    + P SS+T            +P  S T   +   T + R  + +      +  
Sbjct: 659  PTT----HFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTE 714

Query: 864  ----PGTSSSQCCTQKENLRPSSPHRSTQWNNPRN--------------SSPHRTNKDIP 905
                PG++++   ++      SSP   T   +P +              S P  T+  + 
Sbjct: 715  ITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS 774

Query: 906  WASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDPPQSSF 965
             AS        +     S SR       +         G+ P T+  SRPA       + 
Sbjct: 775  PASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEP-TTFHSRPASTHTTLFTE 833

Query: 966  GPTQYNLPSRATSSSHNPGHQSTSRTS----------SPVYPAAYGAPLTSPEPSQPPCA 1015
              T   L   +T+   +P    T   +          S  +P++ G+  T   P++   +
Sbjct: 834  DSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTS 893

Query: 1016 VCIGHRDAPRASSPPRYLQHDPFPFFP-EPRAPESEPPHHEPPYIPPAVCIG-------- 1066
              +G     R S  P   +    P  P  P   E     +  P  P A            
Sbjct: 894  GLVGESTPSRLS--PSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGV 951

Query: 1067 HRDAPRASSPPRHTQFDPFPFLPDTSD------AEHQCQSPQHEPLQLPAPVC--IGYRD 1118
              ++  + S P  T    FP    TSD        H  Q      L   +     +G + 
Sbjct: 952  SEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQS 1011

Query: 1119 APRASSPPRQAPEPSLLFQD-LPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSP 1177
                SSP     E +LL  D +     E+  P+  S        TP           S+ 
Sbjct: 1012 TTFHSSP--GDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTT 1069

Query: 1178 PRQAPEPSLFFQDPPGTSMESLAPSTDSLHGSPVLIP-------QVCIGHRDAPRA--SS 1228
             +  P  S     PPGT+   +  ST + H  P   P          +G  +      SS
Sbjct: 1070 FQSWPSSSDTTPSPPGTTAAPVEVST-TYHSRPSSTPTTHFSASSTTLGRSEESTTVHSS 1128

Query: 1229 P--------PRHPPSDLAFLAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVLADLPPPR 1280
            P        P    + +    P+ SP SSG +  +A PG T      E+ T     P   
Sbjct: 1129 PGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSP--- 1185

Query: 1281 RLAQRQPGPQAQCSSG------------GRTHS---PGRAEVERLFGQERRKSEAAGAFQ 1325
            R       P +  SSG            G TH+   PG   +  +  +      + G+  
Sbjct: 1186 RSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTD 1245

Query: 1326 AQDEGRSQQPSQGQSQLLRRQSSPAPSRQVTMLP 1359
                  S   S    +     SSP  S + T+LP
Sbjct: 1246 TTLSPGSTTASSLGPESTTFHSSPG-STETTLLP 1278



 Score = 65.1 bits (157), Expect = 8e-10
 Identities = 181/805 (22%), Positives = 276/805 (34%), Gaps = 103/805 (12%)

Query: 44   SGAEVPYCDLPRCPPAPEDPLSASTSGC-QSVVDPGLRPGPKRGP-SPSA----GLPEEG 97
            S A   +   PR P     P S ++ G  +       +PG      SP++    GL EE 
Sbjct: 728  SEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEES 787

Query: 98   PTAAPRSRSRELEAVPYLEGLTTSLCGSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTV 157
             T    SR    E   +    TTS+ G       S P S+  +   +D++ S   +  T 
Sbjct: 788  TTVYSSSRG-STETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTA 846

Query: 158  ERQEEEAPSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAG--QKKEDTGGGG 215
                             P  P     A +    P+ LT + +G ++         TG   
Sbjct: 847  ----------------FPGSP-----ASTQTGLPATLTTADLGEESTTFPSSSGSTGTKL 885

Query: 216  RSAGQHWARLRGESG---LSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAAST 272
              A    + L GES    LS     +T    S  TP    +STT   SP   D       
Sbjct: 886  SPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA------ 939

Query: 273  REIPRASSPHRITQRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRA 332
                   SP   T    S  SST       S +Q  ++  ++  + T  +  +QE T  +
Sbjct: 940  -----TLSPATTTSSGVSEESST-------SHSQPGSTHTTAFPDSTTTSDLSQEPT-TS 986

Query: 333  SSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASS 392
             S+Q +T    SP  +T     + S+T   +P  +  T  P  +   +  V+   P  SS
Sbjct: 987  HSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPD-DTITSGLVEASTPTHSS 1045

Query: 393  PN--RTTQRENSRTSCAQRDN-------PKASRTS-SPNRATRDNPRTSCAQRDNPRAS- 441
                 TT    S TS   ++        P +S T+ SP   T      S      P ++ 
Sbjct: 1046 TGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTP 1105

Query: 442  ----SPSRATRDNPTTSCAQRDNPRASRTS-SPNRATRD----NPRTSCAQRDNPRASS- 491
                S S  T      S     +P A+ T+  P R+        P TS     +   ++ 
Sbjct: 1106 TTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTAL 1165

Query: 492  -PSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPT 550
              S  T      S     +PR+  T+    +T  +  +  +   + R  S +  A    T
Sbjct: 1166 PGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGST 1225

Query: 551  TSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRA----SSPNRATR----DNPTTS- 601
            T         AS +S  +  T  +P ++ A    P +    SSP         DN T S 
Sbjct: 1226 TMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASG 1285

Query: 602  CAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCA---RRDDP 658
              +   P  S T SP+        T+         S P+      +P T+ +        
Sbjct: 1286 LLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTT 1345

Query: 659  RASSPNRTIQQENPRTSCALRDNPRA----SSPSRTIQQENPRTS----CAQRDDPRASS 710
               SP+ T       +S  L  +  +    SSP  T    +P  S      +      SS
Sbjct: 1346 SHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSS 1405

Query: 711  PNRTTQQENPRTSCA--RRDNPRA--SSRNRTIQRDNPRTSCAQRDNPRA--SSPNRTIQ 764
            P  T     P +S A  R +  R   SS   TI    P T+ A  + P +  SSP  +I 
Sbjct: 1406 PGSTQTMHFPESSTASGRSEESRTSHSSTTHTIS-SPPSTTSALVEEPTSYHSSPG-SIA 1463

Query: 765  QENLRTSCTRQDNPRTSSPNRATRD 789
              +   S T       S+ + ++ D
Sbjct: 1464 TTHFPESSTTSGRSEESTASHSSPD 1488



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 170/874 (19%), Positives = 281/874 (32%), Gaps = 144/874 (16%)

Query: 86   GPSPSAGLPEEGPTAAPRSRSRELEAVPYLEGLTTSLCGSCNEDPGSDPTSSPDSATPDD 145
            G +P+   P    T+    +S    + P   G T S   S     G   TS     + + 
Sbjct: 656  GSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEI 715

Query: 146  TSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAG 205
            T+   S             P   E +              SS R+P+  T SP    + G
Sbjct: 716  TTLPGSTT----------TPGLSEASTTFY----------SSPRSPTT-TLSPASMTSLG 754

Query: 206  QKKEDTGGGGRSAGQHWARLRGESGLSLERHRSTLTQASSMTPHSGPRSTT--SQASPAQ 263
              +E T    +    H                ST++ AS+ TP     STT  S +  + 
Sbjct: 755  VGEESTTSRSQPGSTH----------------STVSPASTTTPGLSEESTTVYSSSRGST 798

Query: 264  RDTAQAASTREIPRASSPHRITQRDTSRASSTQQEISRASSTQQETSR----ASSTQEDT 319
              T    ST        P     R  S  ++   E S  S   +E++      +STQ   
Sbjct: 799  ETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGL 858

Query: 320  PRASSTQ---EDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRE 376
            P   +T    E++    S+  +T    SP+RST       S+  + +P ++  T  P   
Sbjct: 859  PATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPG-- 916

Query: 377  NPRTPCVQQDD------PRAS----SPNRTTQRENSRTSCAQRDNPKASRTSSPNRATRD 426
            +P TP + +        PR+     SP  TT    S  S      P ++ T+    A  D
Sbjct: 917  SPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTT----AFPD 972

Query: 427  NPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDN-PRTSCAQRD 485
            +  TS   ++              PTTS + + +  A  T SP   T  +  + S     
Sbjct: 973  STTTSDLSQE--------------PTTSHSSQGSTEA--TLSPGSTTASSLGQQSTTFHS 1016

Query: 486  NPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAA 545
            +P  +  +    D  T+   +   P  S T S +        TS   ++         ++
Sbjct: 1017 SPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSS 1076

Query: 546  RDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQR 605
             D   +       P  +  +    +T  + R S     +  ASS      +  TT     
Sbjct: 1077 SDTTPS-------PPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTV---H 1126

Query: 606  DNPRASRTSS-PNRATRD----NPRTSCAQRDNPRASS-PNRTTQQDSPRTSCARRDDPR 659
             +P A+ T+  P R+        P TS     +   ++ P  TT       S      PR
Sbjct: 1127 SSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPR 1186

Query: 660  ASSPNRTIQQENPRTSCALRDNPRASS-PSRTIQQENPRTSC----AQRDDPRASSPNRT 714
              SP+ T+   +  +S    ++  + S P  T     P ++     +Q      SSP  T
Sbjct: 1187 --SPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGST 1244

Query: 715  TQQENPRTSCARRDNPRAS-------SRNRTIQRDNPRTS----CAQRDNPRASSPNRTI 763
                +P ++ A    P ++       S   T+  DN   S     +   +    SP+ T+
Sbjct: 1245 DTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTL 1304

Query: 764  QQENLRT-------------------------------SCTRQDNPRTSSPNRATRDNPR 792
                  T                               S T   +P ++     +  +  
Sbjct: 1305 SPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTT 1364

Query: 793  TSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRD 852
               ++      SSP+      +P       +   S+    +P ++ T       T + R 
Sbjct: 1365 LGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRS 1424

Query: 853  RTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRS 886
                 S        SS    T      P+S H S
Sbjct: 1425 EESRTSHSSTTHTISSPPSTTSALVEEPTSYHSS 1458



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 104/498 (20%), Positives = 176/498 (35%), Gaps = 54/498 (10%)

Query: 63   PLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTAAPRSRSRELEAVPYLEGLTTSL 122
            P  +ST    + + P          S SAGL EE  T   +S     +  P   G T + 
Sbjct: 1041 PTHSSTGSLHTTLTPA--------SSTSAGLQEESTTF--QSWPSSSDTTPSPPGTTAAP 1090

Query: 123  CGSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGP 182
                     S    S  S+TP    ++SS    T+ R EE                  G 
Sbjct: 1091 VEV------STTYHSRPSSTPTTHFSASST---TLGRSEESTTVHSSPGAT-------GT 1134

Query: 183  RADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRSTLTQ 242
                ++ A S+L   P     +    E T   G +     +        S     +TL+ 
Sbjct: 1135 ALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSP 1194

Query: 243  ASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEISRA 302
            AS+ +      STTS + P    T     +  +P  S     +    S   ST   +S  
Sbjct: 1195 ASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASH---SSPGSTDTTLSPG 1251

Query: 303  SSTQQETSRASSTQEDTPRASST---QEDTPRASSTQWNTPRASSPSRSTQLDNPRTSST 359
            S+T       S+T   +P ++ T    ++T  +   + +TP  SS        +P  S+T
Sbjct: 1252 STTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTT 1311

Query: 360  QQDNPQT--SFPTCTPQRENPRTPC---VQQDDPRASSPNRTTQRENSRTSCAQRDNPKA 414
            +Q    T  S+P+       P T     V+       SP+ T     S +S     + ++
Sbjct: 1312 RQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEES 1371

Query: 415  SRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDN-PTTSCAQRDNPRASRTSSPNRAT 473
            +   S   AT   P             SP+R+T       S A   +P +++T     ++
Sbjct: 1372 TTVHSSPVATATTP-------------SPARSTTSGLVEESTAYHSSPGSTQTMHFPESS 1418

Query: 474  RDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQR 533
              + R   ++      SS +      P+T+ A  + P +  +S  + AT   P +S    
Sbjct: 1419 TASGR---SEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSG 1475

Query: 534  DNPRASSPNRAARDNPTT 551
             +  +++ + +   N  T
Sbjct: 1476 RSEESTASHSSPDTNGIT 1493


>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
          Length = 1564

 Score = 84.0 bits (206), Expect = 2e-15
 Identities = 185/882 (20%), Positives = 310/882 (35%), Gaps = 112/882 (12%)

Query: 184  ADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRSTLTQA 243
            +DS+ R PS+  R              TG    +  ++W +    +G  L  + +T    
Sbjct: 17   SDSTSRRPSVFERLG----------PSTGSTAETQCRNWLK----TGNCL--YGNTCRFV 60

Query: 244  SSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASS-TQQEISRA 302
               +P     S+  + SP +R T       +  R        +R+T  +SS  ++E SR 
Sbjct: 61   HGPSPRGKGYSSNYRRSP-ERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRG 119

Query: 303  SSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQD 362
               ++E  +   T+E TP +           + +W T R  S +     D     S +  
Sbjct: 120  RHREKEDIKI--TKERTPESEE--------ENVEWETNRDDSDNGDINYDYVHELSLEMK 169

Query: 363  NPQTSFPTCTPQRENPR-----------TPCVQQD----DPRASSPNRTTQRENS-RTSC 406
              +        ++EN             +P V +      P     +++ +R++S ++S 
Sbjct: 170  RQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSS 229

Query: 407  AQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSP--------------SRATRDNPT 452
            A + + K S  SSP    + N +T+ +++  PR  SP                  +    
Sbjct: 230  ASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDR 289

Query: 453  TSCAQRDNPRASRTSSPNRATRDNPRTS--CAQRDNPRASSPSRATRDNPTTSCAQRDNP 510
                 RD     R     R  RD PR++    Q  +P +S    ++  + ++      +P
Sbjct: 290  IEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSP 349

Query: 511  RASRTSSPNRATRDNP--RTSCAQRDNPRASSPNR----AARDNPTTSCAQRDNPRASRT 564
            R  RT SP+      P  R S +   +   SSP R        +P     + D+ R S++
Sbjct: 350  RRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQS 409

Query: 565  SSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDN--PRASRTSSPNRATRD 622
                   R++ R    +RD  + S   R    + ++S   RD+  PR  R     R TRD
Sbjct: 410  HDRRHERREDTR---GKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRD 466

Query: 623  NP--RTSCAQRDNPRASSPNRTTQQD-SPRTSCARRD--DPRASSPNRTIQQEN--PRTS 675
                R S   RD+      +R T++   PR S + RD  D R      T ++E+  P  S
Sbjct: 467  RRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEES 526

Query: 676  CALRDNPRASSPSRT-IQQENPRTSCAQ-RDDPRASSPNRTTQQENPRTSCARRDNPRAS 733
             +   N      SRT I+ E+   S ++ R+D    S  R  +              + S
Sbjct: 527  RSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPE-----------KGS 575

Query: 734  SRNRTIQRDNPRTSCAQRDN--PRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNP 791
              +R  Q D+  ++    D+   R+S P R    E        +D  R SS  R   +  
Sbjct: 576  RGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPER-----DNRDQARDSSFERRHGERD 630

Query: 792  RTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQR 851
            R    +RD  R SSPIR   +++     ++   R      D       +RD  R    +R
Sbjct: 631  RRDNRERDQ-RPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRER 689

Query: 852  DRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPL 911
            +R +     R+       +    +E  R     R  + +  R+    R  +         
Sbjct: 690  ERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKER 749

Query: 912  RPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQYN 971
               + +  R     R ++ E        R  + +R +     R  Q D      G     
Sbjct: 750  EREREERERERERERERERE--------RERERERARERDKERERQRDWEDKDKGRDDRR 801

Query: 972  LPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPP 1013
                      NP      R S   Y         SP P Q P
Sbjct: 802  EKREEIREDRNPRDGHDERKSKKRYRNE-----GSPSPRQSP 838



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 158/818 (19%), Positives = 266/818 (32%), Gaps = 111/818 (13%)

Query: 264  RDTAQAASTREIPRASSPHRITQR---DTSRASSTQQEISRASSTQ--QETSRASSTQED 318
            RDT ++   R+       H    R   DT R   T  E SR+      +E S  +  + +
Sbjct: 487  RDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNE 546

Query: 319  TPRASSTQEDTPRASSTQWNTP----RASSPSRSTQLDNPRTSSTQQDNPQT--SFPTCT 372
            +   S ++    R   ++   P    + S  SR +Q+D+  ++S   D+ +T  S+P   
Sbjct: 547  SRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERD 606

Query: 373  --PQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSSPNRATRDNPRT 430
              P+R+N       +D  R SS  R   R   R    +RDN +  R   P+   R   R 
Sbjct: 607  RYPERDN-------RDQARDSSFER---RHGERD---RRDNRE--RDQRPSSPIRHQGRN 651

Query: 431  SCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRAS 490
               +RD  R         D       +RD  R           R+  R    +R+  R  
Sbjct: 652  DELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDR----EREKEREL 707

Query: 491  SPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPT 550
               RA R+       +RD  R           R+  R    +R+  R        R+   
Sbjct: 708  ERERA-REREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERER 766

Query: 551  TSCAQRDNPRASRTSSPNRATRD------------NPRTSCAQRDNPRASSPNRATRDNP 598
                +R+  RA          RD              R    +  NPR     R ++   
Sbjct: 767  ERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRY 826

Query: 599  TT--SCAQRDNPRASRTSSP-----NRATRDNPR----TSCAQRDNPRASSPNRTTQQDS 647
                S + R +P+  R  SP     N     N +    +   +    R+ SP+  T+   
Sbjct: 827  RNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQ 886

Query: 648  PRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPR 707
             R     R   R  S  R  +QE      ++ D  R  +      +   +          
Sbjct: 887  GRWKEEDRKPERKESSRRYEEQELKEKVSSV-DKQREQTEILESSRMRAQDIIGHHQSED 945

Query: 708  ASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSC--AQRDNPRASSPNRTIQQ 765
              + +R   +   +    ++   +    +  I+R N  T+    Q  +P+     ++I++
Sbjct: 946  RETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEK 1005

Query: 766  ENLRTS----CTRQDNPRTSSPNRATRDNPRTSCAQRDNL-RASSPIRATQQDNPRTCIQ 820
            +  ++      + ++  + S   R  R  P T+  +   +    + I    Q    T   
Sbjct: 1006 KRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFS 1065

Query: 821  ----QNIP-RSSSTQQDNPKTSCTKRDNLRP-----------------------TCTQRD 852
                +++P R+  T+ ++  T+ T      P                         T   
Sbjct: 1066 DWSDEDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAA 1125

Query: 853  RTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRN-SSPHRTNKDIPWA---- 907
               SFS       TS++   T          HR           +PH T +D        
Sbjct: 1126 AATSFSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMD 1185

Query: 908  ---SFPLRPTQSDGPRTSSPSRSKQSEVPWAS--------IALRPTQGDRPQTSSPSRPA 956
               S  L   +S+   TS   RS  ++    S          L     DR +T S     
Sbjct: 1186 QKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITG 1245

Query: 957  QHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSP 994
            +    +S     +   PSR+TSS        +SR SSP
Sbjct: 1246 ER---KSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSP 1280



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 103/553 (18%), Positives = 199/553 (35%), Gaps = 48/553 (8%)

Query: 247  TPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEISRASSTQ 306
            +P S   ++    +   R  +Q    +E  R+ SP  +T+    R     ++  R     
Sbjct: 845  SPDSDAYNSGDDKNEKHRLLSQVVRPQE-SRSLSPSHLTEDRQGRWKEEDRKPER----- 898

Query: 307  QETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQD-NPQ 365
            +E+SR    QE   + SS  +   +    + +  RA       Q ++  TS    D N +
Sbjct: 899  KESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKK 958

Query: 366  TSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSSPNRATR 425
             +     P ++       ++DD      N  T  E+ +    ++   K S      ++  
Sbjct: 959  KAKIQKKPIKKK------KEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKG 1012

Query: 426  DNPRTSCAQRDNPRASSPSRATRDNPTTSCAQ------------RDNPRASRTSSPNRAT 473
            D+     +  +  + S   R  R  P T+  +             D+ +   T+  + + 
Sbjct: 1013 DS---DISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSD 1069

Query: 474  RDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQR 533
             D P  +        A++ +  +  +P +S      P A+ T++   AT      + A  
Sbjct: 1070 EDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATS 1129

Query: 534  DNPRASSPNRAARDNPTTS--CAQRDNPRASRTSSPNRATRDNPRTSCAQRDNP----RA 587
             +  A + + +A    TT+   A  D+ R    +   +    +     AQ   P    R+
Sbjct: 1130 FSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRS 1189

Query: 588  SS--PNRATRDNPTTSCAQRDNPRASRTSSP--------NRATRDNPRTSCAQRDNPRAS 637
            SS   NR+ R + +       N  A R+           +  +RD  +T   +    R S
Sbjct: 1190 SSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKS 1249

Query: 638  SPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPR 697
              ++  + +  R++ + R D R+ S  R+  + + +                  + E+ R
Sbjct: 1250 RIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDR 1309

Query: 698  TSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRAS 757
                +R D R    +R   ++ PR     RD  R   R R  +RD  R    +R+   + 
Sbjct: 1310 ERERERRDTRQREWDRDADKDWPR----NRDRDRLRERERERERDKRRDLDRERERLISD 1365

Query: 758  SPNRTIQQENLRT 770
            S  R   ++  RT
Sbjct: 1366 SVERDRDRDRDRT 1378


>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis
           critical region 1 [Homo sapiens]
          Length = 1400

 Score = 81.3 bits (199), Expect = 1e-14
 Identities = 178/890 (20%), Positives = 299/890 (33%), Gaps = 101/890 (11%)

Query: 126 CNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGPRAD 185
           CN    S PT  P       T NS ++D  +     E  P+ +E               +
Sbjct: 149 CNTTRHSKPTDKP-------TGNSKTIDHKSSTDNHEAPPTSEE---------------N 186

Query: 186 SSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERH---RSTLTQ 242
           SS +    + R+    D A    + T     SAG+       +S ++  +    +ST+T+
Sbjct: 187 SSNQGKDPMIRNQRSVDPA----DSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTVTR 242

Query: 243 ASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASST-QQEISR 301
            S  T     +S +         T    ST      +S H      T + S++  ++I+ 
Sbjct: 243 KSDKTGRPLEKSMS---------TLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITA 293

Query: 302 ASSTQQETSRASSTQEDTPRASSTQEDTPRA-------SSTQWNTPRASSPSRSTQLDNP 354
           AS T  +T+        TP  S   ED+          + T  N     S +  TQ    
Sbjct: 294 ASKTTYKTT-------GTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAE 346

Query: 355 RTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKA 414
            T    +   + + P+     EN      +      + P    +R  +  +      P  
Sbjct: 347 PTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPTENRERTANENTAPFPAGPTE 406

Query: 415 SRTSSPNRATRDNPR--TSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRA 472
           +R  + N  T   P   T   +R     ++PS A    PT    +  N   + T SP   
Sbjct: 407 NREMTANENTTLFPAEPTEHGERTANENTTPSPA---EPTEHGERTAN--ENTTPSPAEP 461

Query: 473 TRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDN--PRASRTSSPNRATRDNPRTSC 530
           T    RT  A  ++   SS + +T     T  A  +     A  T +  R   +N   S 
Sbjct: 462 TEHGERTPFA--NDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSP 519

Query: 531 AQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTS-SPNRATRDNPRTSCAQRDNPRASS 589
           A     R ++ N     +P      R+     +T+ SP   T +  RT  A      +S+
Sbjct: 520 AGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSA 579

Query: 590 -----------PNRATRDNPTTSCAQRDNPRASRTS-SPNRATRDNPRTSCA-QRDNPRA 636
                       N  T  +P      R+     +T+ SP   T +  RT  A ++  P  
Sbjct: 580 EPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSL 639

Query: 637 SSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSR-TIQQEN 695
           + P    Q    RT  A      +S+     ++  P  +     +P   + +R     EN
Sbjct: 640 AEPTENGQ----RTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANEN 695

Query: 696 PRTSCAQRDDPRASSPNRTTQ--QENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDN 753
              S A   + R  + N  T      P  +  R  N + +S       +  RT  A   N
Sbjct: 696 TTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFA---N 752

Query: 754 PRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQD 813
            + +S +    +   RT    ++   T SP   T +  RT+  +      ++P  A   +
Sbjct: 753 EKTTSSSAEPTEHGERTPLANENT--TLSPAGPTENRERTANEK------TTPFPAEPTE 804

Query: 814 NPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCT 873
           N      +N   S +   +N   +    +   P+  +       +   +   TSSS   T
Sbjct: 805 NRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPT 864

Query: 874 QKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVP 933
           +     P +   +T        +  RT  +     FP  PT++      S +  K +  P
Sbjct: 865 EHAERTPLANENTTSSPAEPTENRERTANE-KTTQFPAEPTEN----RESTANEKTTPFP 919

Query: 934 WASIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNP 983
                 R    +   T SP+ P +H+             P R  S +  P
Sbjct: 920 AEPTENREWTANENTTLSPAEPTEHEEMTPLMVDENLQAPFRQGSCAERP 969



 Score = 69.3 bits (168), Expect = 4e-11
 Identities = 173/845 (20%), Positives = 289/845 (34%), Gaps = 118/845 (13%)

Query: 254  STTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEISRASSTQQETSRAS 313
            +T S A P +    + A+    P  + P    +R       T    S A ST+       
Sbjct: 435  TTPSPAEPTEHGE-RTANENTTPSPAEPTEHGERTPFANDKTTS--SSAESTEHGERTPL 491

Query: 314  STQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQ--------------LDNPRTSST 359
            + +  TP  +   E+  R ++    TP  + P+ + +               +N  T++ 
Sbjct: 492  ANENTTPSPAEPTENRERTANEN-TTPSPAGPTENRETTANEKTTLSPVEPTENRETTAN 550

Query: 360  QQDNPQTSFPTCTPQR---ENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASR 416
            ++  P  + PT   QR    N +T      +P           EN+  S A+   P  +R
Sbjct: 551  EKTTPSPAEPTENGQRTPFANEKTTS-SSAEPTEHGERTPLANENTTPSPAE---PTENR 606

Query: 417  TSSPNRATRDNPRTSCAQRD-NPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRD 475
              + N  T  +P       D  P A+  +  +   PT +  +        TSS    T  
Sbjct: 607  ERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEH 666

Query: 476  NPRTSCA-QRDNPRASSPS----RATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSC 530
              RT  A +   P  + P+    R   +N T S A    P  +R  + N  T   P    
Sbjct: 667  EERTPLANENTTPSPAEPTENRERTANENTTPSPA---GPTENREMTANEKTTLFPAEPT 723

Query: 531  AQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRD---NPRA 587
              R+   A+    ++   PT +  +        TSS    T    RT  A  +   +P  
Sbjct: 724  ENRER-TANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAG 782

Query: 588  SSPNR-ATRDNPTTSCAQRDNPRASRTS------SPNRATRDNPRTSCA-QRDNPRASSP 639
             + NR  T +  TT           RT+      SP + T +  RT  A ++  P  + P
Sbjct: 783  PTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEP 842

Query: 640  ----NRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCA-LRDNPRASSPSRTIQ-- 692
                 RT   +   TS +   +P   +    +  EN  +S A   +N   ++  +T Q  
Sbjct: 843  TENGKRTPFANEKTTSSSA--EPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFP 900

Query: 693  ---QENPRTSCAQRDDPRASSPNRT---TQQENPRTSCA---RRDNPRASSRNRTIQRDN 743
                EN  ++  ++  P  + P      T  EN   S A     +       +  +Q   
Sbjct: 901  AEPTENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLMVDENLQAPF 960

Query: 744  PRTSCAQRDNPRASSPNRTIQQEN-----LRTSCTRQDNPRTSSPNRATRDNPRTSCAQ- 797
             + SCA+R     ++   T   E+     + TS T   +   SS   +T      S A  
Sbjct: 961  RQGSCAERPKDICATVASTTGSESSTASEIITSSTMSVSATASSTASSTASEITMSSAAI 1020

Query: 798  ----------RDNLRASSPIRATQQDNPRTCIQQNIPR--SSSTQQDNPKTSCTKRDNLR 845
                      R +   S P+ A+      T     +    +SST    P T+ T      
Sbjct: 1021 PVSSTAYETIRFSTAVSEPVTASILALESTLAFTTVSNTTTSSTVTSVPTTASTSGSKNT 1080

Query: 846  PTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSS-PHRSTQWNNPRNSSPHRTNKDI 904
              C   + T S +       +  +   TQ   +   S PH +T+   P +++    +  +
Sbjct: 1081 TAC---EATMSETTIAAITASEDTTVSTQTSVIAAESVPHTATK--TPTDTTTASVSATV 1135

Query: 905  PWAS--FPLRPTQSDGPRTSSPSRSKQSEVPWAS-----------IALRPTQGDRPQTSS 951
            P  +    +  T S  P T+S + +  S+    S              + T G    T+S
Sbjct: 1136 PKNNTLSVITSTPSTAPNTASKTMTTASKTTTTSTITSLPTTVFTTTSKITAGSEIPTAS 1195

Query: 952  PSRPAQHDPPQSSFGPTQYNLPSRA-----------------TSSSHNPGHQSTSRTSSP 994
             +  A       + G T  + PS A                 T+ S N GH + S   + 
Sbjct: 1196 TTDSATTAISTKASGTTVESAPSTAPPTPAETTTASVPTTTSTTGSENTGHHTVSSVPTT 1255

Query: 995  VYPAA 999
            V+  A
Sbjct: 1256 VFATA 1260



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 152/787 (19%), Positives = 260/787 (33%), Gaps = 116/787 (14%)

Query: 11   EHFEANILTQNRCQNCFHPEEAHGARY-QELRSPSGAEVPYCDLPRCPPAPEDPLSASTS 69
            EH E     +N   +   P E HG R   E  +PS AE P     R P A +   S+S  
Sbjct: 425  EHGERTA-NENTTPSPAEPTE-HGERTANENTTPSPAE-PTEHGERTPFANDKTTSSSAE 481

Query: 70   GCQS-----VVDPGLRPGPKRGPSPSAGLPEEGPTAAPRSRSRELEAVPYLEGLTTSLCG 124
              +      + +    P P            E  T +P   +   E     +   + +  
Sbjct: 482  STEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEP 541

Query: 125  SCNEDPGSDPTSSPDSATPDDTSN-----SSSVDWDTVERQE--EEAPSWDELAVMIPRR 177
            + N +  ++  ++P  A P +        +      + E  E  E  P  +E     P  
Sbjct: 542  TENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAE 601

Query: 178  PREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHR 237
            P E     ++++     T SP          E T  G R+             L+ E+  
Sbjct: 602  PTENRERTANEKT----TPSPA---------EPTENGDRTP------------LANEKTT 636

Query: 238  STL---TQASSMTPHSGPRSTTSQASPAQ-RDTAQAASTREIPRASSPHRITQRDTSRAS 293
             +L   T+    TP +  ++T+S A P +  +    A+    P  + P       T    
Sbjct: 637  PSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEP-------TENRE 689

Query: 294  STQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDN 353
             T  E +  S      +R  +  E T    +   +    ++ +  T   + P+ + Q   
Sbjct: 690  RTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQ--- 746

Query: 354  PRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQD---DPRASSPNRTTQRENSRTSCAQRD 410
                 T   N +T+  +  P     RTP   ++    P   + NR        T      
Sbjct: 747  ----RTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAGPTENRERTANEKTTPFPAEP 802

Query: 411  NPKASRTS------SPNRATRDNPRTSCA-QRDNPRASSPSRATRDNP-----TTSCAQR 458
                 RT+      SP + T +  RT  A ++  P  + P+   +  P     TTS +  
Sbjct: 803  TENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAE 862

Query: 459  DNPRASR--------TSSPNRATRDNPRTS-------CAQRDNPRASSPSRATRDNPTTS 503
                A R        TSSP   T +  RT+        A+    R S+ +  T   P   
Sbjct: 863  PTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEP 922

Query: 504  CAQRD-NPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRAS 562
               R+     + T SP   T     T     +N +A     +  + P   CA   +   S
Sbjct: 923  TENREWTANENTTLSPAEPTEHEEMTPLMVDENLQAPFRQGSCAERPKDICATVASTTGS 982

Query: 563  RTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDN---PTTSCAQRDNPRASRTSSPNRA 619
             +S+ +     +  +  A   +  +S+ +  T  +   P +S A      ++  S P  A
Sbjct: 983  ESSTASEIITSSTMSVSATASSTASSTASEITMSSAAIPVSSTAYETIRFSTAVSEPVTA 1042

Query: 620  ------------TRDNPRTSCAQRDNPRASSPN--------RTTQQDSPRTSCARRDDPR 659
                        T  N  TS      P  +S +          T  ++   +    +D  
Sbjct: 1043 SILALESTLAFTTVSNTTTSSTVTSVPTTASTSGSKNTTACEATMSETTIAAITASEDTT 1102

Query: 660  ASSPNRTIQQEN-PRTSCALRDNPRASSPSRTIQQENPRT--SCAQRDDPRASSPNRTTQ 716
             S+    I  E+ P T+     +   +S S T+ + N  +  +      P  +S   TT 
Sbjct: 1103 VSTQTSVIAAESVPHTATKTPTDTTTASVSATVPKNNTLSVITSTPSTAPNTASKTMTTA 1162

Query: 717  QENPRTS 723
             +   TS
Sbjct: 1163 SKTTTTS 1169



 Score = 40.0 bits (92), Expect = 0.027
 Identities = 55/257 (21%), Positives = 94/257 (36%), Gaps = 33/257 (12%)

Query: 241  TQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDT---SRASSTQQ 297
            TQ S +   S P + T   +    DT  A+ +  +P+ ++   IT   +   + AS T  
Sbjct: 1105 TQTSVIAAESVPHTATKTPT----DTTTASVSATVPKNNTLSVITSTPSTAPNTASKTMT 1160

Query: 298  EISRASSTQQETSRASSTQEDT---------PRASSTQEDTPRASSTQWNTPRASSPS-- 346
              S+ ++T   TS  ++    T         P AS+T   T   S+    T   S+PS  
Sbjct: 1161 TASKTTTTSTITSLPTTVFTTTSKITAGSEIPTASTTDSATTAISTKASGTTVESAPSTA 1220

Query: 347  -----RSTQLDNPRTSSTQQDN----------PQTSFPTCTPQRENPRTPCVQQDDPRAS 391
                  +T    P T+ST              P T F T +       T          +
Sbjct: 1221 PPTPAETTTASVPTTTSTTGSENTGHHTVSSVPTTVFATASESSTGSETTRASTSATEVT 1280

Query: 392  SPNRTTQRENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNP 451
            +   T     S T+      P  +  S  + AT    +T+ A      +++  + T D+ 
Sbjct: 1281 TAMTTAMTTGSETAVVSTKAPVTTTQSGFSTATVMPAKTTTASVSTTASTTLYQNTIDSV 1340

Query: 452  TTSCAQRDNPRASRTSS 468
              S    D+  AS++++
Sbjct: 1341 AKSVPTMDSTIASKSTT 1357



 Score = 39.7 bits (91), Expect = 0.035
 Identities = 89/416 (21%), Positives = 142/416 (34%), Gaps = 35/416 (8%)

Query: 1346 QSSPAPSRQVTMLPAKQAELTRRSQAE--PPHPWSPEKRPE--GDRQLQGSPLPPRTSAR 1401
            + +P  +   T  PA+  E   R+  E   P P  P +  E   + +   SP+ P  +  
Sbjct: 487  ERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRE 546

Query: 1402 TPERELRTQRPLESGQAGPRQPLGVWQSQEEPPGSQGPHRHLERSWSSQEGGLGPGGWWG 1461
            T   E  T  P E  + G R P   + +++    S  P  H ER+  + E          
Sbjct: 547  TTANEKTTPSPAEPTENGQRTP---FANEKTTSSSAEPTEHGERTPLANENTTP-----S 598

Query: 1462 CGEPSLGAAKAPEGAWGGTSREYKESWGQPEAWEEKPTHEL--PRELGKRSPLTSPPENW 1519
              EP+    +        +  E  E+  +     EK T  L  P E G+R+P  +  E  
Sbjct: 599  PAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFAN--EKT 656

Query: 1520 GGPAESSQSWHSGTPTAVGWGAEGACPYPRGSERRPELDWRDLLGLLRAPGEGVWARVPS 1579
               +         TP A     E   P P       E    +      +P      R  +
Sbjct: 657  TSSSAEPTEHEERTPLA----NENTTPSPAEPTENRERTANE--NTTPSPAGPTENREMT 710

Query: 1580 LDWEGLLELLQARLPRKDPAGHRDDLARALGPELG--PPGTNDVPEQESHSQPEGWAEAT 1637
             + +  L   +    R+  A  +   + A   E G   P  N+     S ++P    E T
Sbjct: 711  ANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANE-KTTSSSAEPTEHGERT 769

Query: 1638 PVNGHSPALQSQSPVQLPSPACT--STQWPKIKVTRGPATATLAGLEQTGPLGSRSTAKG 1695
            P+   +  L    P +         +T +P         TA     E T P  ++ T  G
Sbjct: 770  PLANENTTLSPAGPTENRERTANEKTTPFPAEPTENRERTAN----ENTTPSPAQPTENG 825

Query: 1696 PSLPELQFQPEEPEESEPSRG--QDPLTDQKQADSADKRPAEGKAGSPLKGRLVTS 1749
               P L  +   P  +EP+    + P  ++K   S+   P E    +PL     TS
Sbjct: 826  DRTP-LANEKTTPSLAEPTENGKRTPFANEK-TTSSSAEPTEHAERTPLANENTTS 879



 Score = 39.7 bits (91), Expect = 0.035
 Identities = 62/298 (20%), Positives = 110/298 (36%), Gaps = 21/298 (7%)

Query: 238  STLTQASSMTPHSGPRSTTS----------QASPAQRDTAQAASTREIPRASSPHRITQR 287
            ST+T   +    SG ++TT+           A  A  DT  +  T  I   S PH  T+ 
Sbjct: 1063 STVTSVPTTASTSGSKNTTACEATMSETTIAAITASEDTTVSTQTSVIAAESVPHTATKT 1122

Query: 288  DTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRA--SSP 345
             T   +++       ++T    +   ST  +T   + T       +ST  + P    ++ 
Sbjct: 1123 PTDTTTASVSATVPKNNTLSVITSTPSTAPNTASKTMTTASKTTTTSTITSLPTTVFTTT 1182

Query: 346  SRSTQLDNPRTSSTQQDNPQTSFPT----CTPQRENPRTPCVQQDDPRASSP--NRTTQR 399
            S+ T      T+ST  D+  T+  T     T +      P    +   AS P    TT  
Sbjct: 1183 SKITAGSEIPTAST-TDSATTAISTKASGTTVESAPSTAPPTPAETTTASVPTTTSTTGS 1241

Query: 400  ENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRD 459
            EN+              T+S +    +  R S +  +   A + +  T     T+     
Sbjct: 1242 ENTGHHTVSSVPTTVFATASESSTGSETTRASTSATEVTTAMTTAMTT--GSETAVVSTK 1299

Query: 460  NPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSS 517
             P  +  S  + AT    +T+ A      +++  + T D+   S    D+  AS++++
Sbjct: 1300 APVTTTQSGFSTATVMPAKTTTASVSTTASTTLYQNTIDSVAKSVPTMDSTIASKSTT 1357



 Score = 33.9 bits (76), Expect = 1.9
 Identities = 34/145 (23%), Positives = 60/145 (41%), Gaps = 10/145 (6%)

Query: 229  SGLSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRI---- 284
            + +S +   +T+  A S  P + P  TT+ + P    T  + +T     +S P  +    
Sbjct: 1202 TAISTKASGTTVESAPSTAPPT-PAETTTASVPTTTSTTGSENTGHHTVSSVPTTVFATA 1260

Query: 285  ----TQRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTP 340
                T  +T+RAS++  E++ A +T   T   ++        ++TQ     A+     T 
Sbjct: 1261 SESSTGSETTRASTSATEVTTAMTTAMTTGSETAVVSTKAPVTTTQSGFSTATVMPAKTT 1320

Query: 341  RAS-SPSRSTQLDNPRTSSTQQDNP 364
             AS S + ST L      S  +  P
Sbjct: 1321 TASVSTTASTTLYQNTIDSVAKSVP 1345


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 81.3 bits (199), Expect = 1e-14
 Identities = 125/508 (24%), Positives = 175/508 (34%), Gaps = 83/508 (16%)

Query: 939  LRPTQGDRPQTSSPSRPAQHDPPQSS-FGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYP 997
            L P   + P +  P       PP++S   P    LP+     +    H S     SP+ P
Sbjct: 440  LLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEAL---HLSRPLEESPLSP 496

Query: 998  AAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESEPPHHEPP 1057
                +PL+ P  S P   +       P  S P   L+    P  P P A    PP  E P
Sbjct: 497  PPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALET---PLSPPPEASPLSPPFEESP 553

Query: 1058 YIPPAVCIGHRDAPRASS---PPRHTQFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCI 1114
              PP   +     P AS    PP  +   P P        E    SP  E  +L  P   
Sbjct: 554  LSPPPEELPTSPPPEASRLSPPPEESPMSPPP--------EESPMSPPPEASRLFPP--- 602

Query: 1115 GYRDAPRASSPPRQAPEPSLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSF 1174
             + ++P  S PP ++P         P AS  S  P                    D+P  
Sbjct: 603  -FEESP-LSPPPEESP-----LSPPPEASRLSPPPE-------------------DSP-M 635

Query: 1175 SSPPRQAPEPSLFFQDPPGTSMESLAPSTDSLHGSPVLIPQVCIGHRDAPRASSPPRHPP 1234
            S PP ++P        PP  S  S  P    L   P   P        +P     P  PP
Sbjct: 636  SPPPEESP-----MSPPPEVSRLSPLPVVSRLSPPPEESPL-------SPPPEESPTSPP 683

Query: 1235 SDLAFLAPSPSPGSSG----GSRGSAPPGETRHNLEREEYTVLADLPPPRRLAQRQPGPQ 1290
             + + L+P P    +      S  S PP ++  +L  EE  +L  LP   +L  R  GP 
Sbjct: 684  PEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLP-LPEEPQLCPRSEGP- 741

Query: 1291 AQCSSGGRTHSPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQSSPA 1350
                     H   R E   L     R  E   + QA++   S QP +     +  +   +
Sbjct: 742  ---------HLSPRPEEPHL---SPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLS 789

Query: 1351 PSRQVTMLPAKQAELTRRSQAEPPHPWSPEKRPEGDRQLQGSPLPPRTSARTPERELRTQ 1410
            P  +   L  +  EL    Q E PH     + P    Q + S L P++     E    + 
Sbjct: 790  PQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQS-----EEPCLSP 844

Query: 1411 RPLESGQAGPRQPLGVWQSQEEPPGSQG 1438
            RP ES  +   +   +    E+PP   G
Sbjct: 845  RPEESHLSPELEKPPLSPRPEKPPEEPG 872



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 132/521 (25%), Positives = 181/521 (34%), Gaps = 97/521 (18%)

Query: 795  CAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRT 854
            C +    +    IR+  + +   C + + P    T  D P       D L   C  + + 
Sbjct: 346  CHRCHKAQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEP-------DALYVACQGQPKG 398

Query: 855  QSF-SFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRP 913
                S Q   PG    QC  + + L  +      Q   P N          P    PL P
Sbjct: 399  GHVTSMQPKEPGPL--QC--EAKPLGKAGVQLEPQLEAPLNEEMPLLP---PPEESPLSP 451

Query: 914  TQSDGPRTSSPSRSKQSEVPW---ASIALRPTQGDRPQTSSPSRPAQHD-----PPQSS- 964
               + P +  P  S+ S  P    AS         RP   SP  P   +     PP+SS 
Sbjct: 452  PPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSP 511

Query: 965  FGPTQYNLPSRATSSSHNPGHQ---STSRTSSPVYPAAYGAPLTSPE---PSQPPCAVCI 1018
            F P + +  S    S  +P  +   S    +SP+ P    +PL+ P    P+ PP     
Sbjct: 512  FSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPP----- 566

Query: 1019 GHRDAPRASSPPRYLQHDP----FPFFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRAS 1074
               +A R S PP      P     P  P P A    PP  E P  PP       ++P  S
Sbjct: 567  --PEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPP-----EESP-LS 618

Query: 1075 SPPRHTQFDPFP-FLPDTSDAEHQCQSPQHEPLQL-PAPVCIGYRDAPRASSPPRQAPEP 1132
             PP  ++  P P   P +   E    SP  E  +L P PV        R S PP ++P  
Sbjct: 619  PPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPV------VSRLSPPPEESP-- 670

Query: 1133 SLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPP 1192
                   P  S  S  P    L   P           D+P+ S PP  +P        PP
Sbjct: 671  ---LSPPPEESPTSPPPEASRLSPPP----------EDSPT-SPPPEDSPA-----SPPP 711

Query: 1193 GTSMESLAPSTDSLHGSPVL----IPQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGS 1248
              S+ SL      L  SP+L     PQ+C      PR+  P   P  +   L+P P    
Sbjct: 712  EDSLMSL-----PLEESPLLPLPEEPQLC------PRSEGPHLSPRPEEPHLSPRPE--- 757

Query: 1249 SGGSRGSAPPGETRHNLEREEYTVLADLPPPRRLAQRQPGP 1289
                   +P  E  H   + E   L  +P    L+ +  GP
Sbjct: 758  ---EPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGP 795



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 203/943 (21%), Positives = 284/943 (30%), Gaps = 198/943 (20%)

Query: 354  PRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPK 413
            P    T  D P   +  C             Q  P+         +E     C  +   K
Sbjct: 375  PEPGDTPTDEPDALYVAC-------------QGQPKGGHVTSMQPKEPGPLQCEAKPLGK 421

Query: 414  ASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRAT 473
            A     P      N        + P    P  +    P         P ASR S P    
Sbjct: 422  AGVQLEPQLEAPLN-------EEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEEL 474

Query: 474  RDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQR 533
              +P         P   SP     +    S     +P +    SP     ++P +     
Sbjct: 475  PASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPAL-- 532

Query: 534  DNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRA 593
            + P +  P  +    P         P    TS P  A+R +P       ++P +  P  +
Sbjct: 533  ETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSP----PPEESPMSPPPEES 588

Query: 594  TRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCA 653
                P         P ASR   P   +  +P         P   SP       SP    +
Sbjct: 589  PMSPP---------PEASRLFPPFEESPLSP---------PPEESPL------SPPPEAS 624

Query: 654  RRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNR 713
            R   P   SP     +E+P             SP   + + +P    ++   P   SP  
Sbjct: 625  RLSPPPEDSPMSPPPEESP------------MSPPPEVSRLSPLPVVSRLSPPPEESPLS 672

Query: 714  TTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCT 773
               +E+P +       P  +SR      D+P TS    D+P +  P  ++    L  S  
Sbjct: 673  PPPEESPTSP------PPEASRLSPPPEDSP-TSPPPEDSPASPPPEDSLMSLPLEESPL 725

Query: 774  RQDNPRTSSPNRATR-DNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQD 832
                P    P    R + P  S       R   P  + + + P    Q   P  S   ++
Sbjct: 726  L---PLPEEPQLCPRSEGPHLS------PRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEE 776

Query: 833  NPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNP 892
                +  +  +L P             Q + P  S           +P   H S     P
Sbjct: 777  PCLCAVPEEPHLSP-------------QAEGPHLSP----------QPEELHLS-----P 808

Query: 893  RNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQTSSP 952
            +   PH        +  P  P  S  P  S    S QSE P  S         RP+ S  
Sbjct: 809  QTEEPH-------LSPVPEEPCLSPQPEES--HLSPQSEEPCLS--------PRPEESHL 851

Query: 953  SRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQP 1012
            S P    PP          L  R       PG            PA    PL  P P +P
Sbjct: 852  S-PELEKPP----------LSPRPEKPPEEPGQ----------CPAPEELPL-FPPPGEP 889

Query: 1013 PCAVCIGHRDAPRASSPPRYLQHDPFPFFP--EPR-APESEPPHHEPPYIPPAVCIGHRD 1069
              +  +G         PP     +  P  P  EP  +P+  PP   PP + P +      
Sbjct: 890  SLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAA--- 946

Query: 1070 APRASSPPRHTQFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPV--CIGYRDAPRASSPPR 1127
            AP A SP    ++ PF    D SD E    +P  E    P P   C      P    PP 
Sbjct: 947  APPALSPLGELEY-PFGAKGD-SDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPS 1004

Query: 1128 Q----APEPSLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPR---Q 1180
                  P   +L + LP   +  L  S+              +     PS  SPP     
Sbjct: 1005 PGSPVGPASPILMEPLPPQCSPLLQHSL--------------VPQNSPPSQCSPPALPLS 1050

Query: 1181 APEPSLFFQDPPGTSMESLAPSTDSLHGSPVLIPQVCIGHRDAPRASSPPRHPPSDLAFL 1240
             P P        G S E+     ++   S    P +       P A+SP   P  DL+  
Sbjct: 1051 VPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPAL------EPSATSPLPSPMGDLSCP 1104

Query: 1241 APSPSPG---SSGGSRGSAP------------PGETRHNLERE 1268
            APSP+P     SG    +AP            PG+T  +L  E
Sbjct: 1105 APSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASE 1147



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 147/645 (22%), Positives = 202/645 (31%), Gaps = 128/645 (19%)

Query: 895  SSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQTSSPSR 954
            SSP     ++ +   P   T   G    +P   K    P AS          PQ+     
Sbjct: 2295 SSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQV-------EPQSPGLGL 2347

Query: 955  PAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPPC 1014
              Q  PP  +  P+              P H    R  S  Y   Y  P  +P P  PP 
Sbjct: 2348 RPQEPPPAQALAPSP-------------PSHPDIFRPGS--YTDPYAQPPLTPRPQPPPP 2392

Query: 1015 AVCIGHRDAPRASSPPRYLQHDPF---PFFPEPRAPESEP----PHHEPPYIPPAVCIGH 1067
              C         + PPR L  DPF   P  P+ ++    P    P     + P  V    
Sbjct: 2393 ESC--------CALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRF 2444

Query: 1068 RDAPRASSPPRHTQF-DPF-----PFLPDTSDAEHQCQSPQHEPL---QLPAPVCIGYRD 1118
            +     S PP   Q  DPF     P  P   +   +  S  H  L     PA +  G   
Sbjct: 2445 QSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAG 2504

Query: 1119 APRASSPPRQAPE-------------PSLLFQDLPRASTESLVPSMDSLHECPHIPTPVC 1165
               A  P  Q P              PS +    P+A  E   PS+      P +P P  
Sbjct: 2505 ELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGE---PSLKPPVPQPGLPPPHG 2561

Query: 1166 IGHR--DAPSFSSPPRQAPEPSLFFQDPPGTSMESLAPSTDSLHG-SPVLIPQVCIGHRD 1222
            I       P+   P       +     P G+ +   + ST   +G SP+  P V      
Sbjct: 2562 INSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVL----- 2616

Query: 1223 APRASSPPRHPPSDLAFLAPSPS--------------PGSSGGSR-------GSAPPG-- 1259
                  PP  P   L +L+   S              PG+  GS        G+  PG  
Sbjct: 2617 ------PPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMS 2670

Query: 1260 -----ETRHNLEREEYTVLADLPPPRRLAQRQPGPQAQCSS---------GGRTHSPGRA 1305
                 E     +R+    L      +R   RQ    A  ++         G    SP   
Sbjct: 2671 GLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFE 2730

Query: 1306 EVER---LFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPSRQVTMLPAKQ 1362
            ++ R    F   + KS   G   ++  G    P    S    R S P P    + +    
Sbjct: 2731 QLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSD--DRLSRPPPPATPSSMDVNS 2788

Query: 1363 AELTRRSQAEPPHPWSPEKRPEGDRQLQGSPLPPRTSARTPERELRTQRPLESGQAGPRQ 1422
             +L   SQA       P   P   +Q Q       T+A +    +  + P   G    RQ
Sbjct: 2789 RQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQ 2848

Query: 1423 PLG---------VWQSQEEPPGSQGPHRHLERSWSSQEGGLGPGG 1458
             LG         +    E  PG  GP + +E   + Q+ GLGPGG
Sbjct: 2849 ALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQK-GLGPGG 2892



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 93/385 (24%), Positives = 137/385 (35%), Gaps = 56/385 (14%)

Query: 79  LRPGPKRGPSPSAGLPEEGPTAAPRSRSR------ELEAVPYLEGLTTSLCGSCNEDPGS 132
           L P P+   SP +  PEE PT+ P   SR      EL A P  E L   L     E P S
Sbjct: 440 LLPPPEE--SPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEAL--HLSRPLEESPLS 495

Query: 133 DPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGPRADSSQRAP- 191
            P      + P ++S  S ++   +   EE  PS   L   +   P   P +   + +P 
Sbjct: 496 PPPEESPLSPPPESSPFSPLEESPLSPPEESPPS-PALETPLSPPPEASPLSPPFEESPL 554

Query: 192 -----SLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESGLSLERHRSTLTQASSM 246
                 L T  P          E++           +     S L      S L+     
Sbjct: 555 SPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEE 614

Query: 247 TPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPH--RITQRD-TSRASSTQQEI---- 299
           +P S P    S+ SP   D+  +    E P +  P   R++     SR S   +E     
Sbjct: 615 SPLS-PPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSP 673

Query: 300 ---SRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWN------------------ 338
                 +S   E SR S   ED+P  S   ED+P +   + +                  
Sbjct: 674 PPEESPTSPPPEASRLSPPPEDSP-TSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEP 732

Query: 339 --TPRASSPSRSTQLDNPRTSSTQQD---NPQTSFPTCTPQRENPRTPCVQQD---DPRA 390
              PR+  P  S + + P  S   ++   +PQ   P  +PQ E P    V ++    P+A
Sbjct: 733 QLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQA 792

Query: 391 SSPNRTTQRENSRTSCAQRDNPKAS 415
             P+ + Q E    S  Q + P  S
Sbjct: 793 EGPHLSPQPEELHLS-PQTEEPHLS 816



 Score = 45.1 bits (105), Expect = 8e-04
 Identities = 84/365 (23%), Positives = 126/365 (34%), Gaps = 57/365 (15%)

Query: 49  PYCDLPRCPPAPEDPLSASTSGCQSVVDPGLRPGPKRGPSPSAGLPEEGPTAAPRSRSRE 108
           P+ + P  PP  E PLS      +      L P P+   SP +  PEE P + P   SR 
Sbjct: 602 PFEESPLSPPPEESPLSPPPEASR------LSPPPE--DSPMSPPPEESPMSPPPEVSR- 652

Query: 109 LEAVPYLEGLT-----TSLCGSCNEDPGS----------DPTSSPDSATPDDTSNSSSVD 153
           L  +P +  L+     + L     E P S           P  SP S  P+D+  S   +
Sbjct: 653 LSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPE 712

Query: 154 WDTVERQEEEAPSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGG 213
              +    EE+P      + +P  P+  PR++    +P               + E+   
Sbjct: 713 DSLMSLPLEESP-----LLPLPEEPQLCPRSEGPHLSP---------------RPEEPHL 752

Query: 214 GGRSAGQHWARLRGESGLSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTR 273
             R    H +    E  LS +     L  A    PH  P++     SP   +   +  T 
Sbjct: 753 SPRPEEPHLSPQAEEPHLSPQPEEPCLC-AVPEEPHLSPQAEGPHLSPQPEELHLSPQTE 811

Query: 274 E---IPRASSPHRITQRDTSRASSTQQEISRASSTQQETSRASSTQED---TPRASSTQE 327
           E    P    P    Q + S  S   +E     S + E S  S   E    +PR     E
Sbjct: 812 EPHLSPVPEEPCLSPQPEESHLSPQSEE--PCLSPRPEESHLSPELEKPPLSPRPEKPPE 869

Query: 328 DTPRASSTQWNT--PRASSPSRSTQLDNPRTSSTQQD--NPQTSFPTCTPQRENPRTPCV 383
           +  +  + +     P    PS S  L  P  S   +   +P       +P  E   +P +
Sbjct: 870 EPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQL 929

Query: 384 QQDDP 388
              DP
Sbjct: 930 MPPDP 934



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 137/611 (22%), Positives = 204/611 (33%), Gaps = 89/611 (14%)

Query: 1083 DPFPFLPDTSD--AEHQCQSPQHEP-LQLPAPVCIGYRDAPRASSPP----RQAPEPSLL 1135
            D  P+L    D  A H+    Q +   Q+     +G  D  R +  P    R  P+P  L
Sbjct: 2056 DKAPYLQKAKDNRAAHRINKVQKQAESQINKQTKVG--DIARKTDRPALHLRIPPQPGAL 2113

Query: 1136 FQDLPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPR-QAPEPS----LFFQD 1190
                P A+    + S          PT        A  F  PP    P P     LF + 
Sbjct: 2114 GSPPPAAAPTIFIGS----------PTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKL 2163

Query: 1191 PPGTSMESLAPSTDSLHGSPVLIPQVCIGHRDAPR-ASSPPRHPPSDLAFLAPSPSPGSS 1249
            PP   + +  PS D    +P    +        PR  ++PP +PP      AP+  P   
Sbjct: 2164 PP--QVPAQVPSQDPFGLAPAYPLE--------PRFPTAPPTYPPYPSPTGAPAQPPMLG 2213

Query: 1250 GGSRGSA---------PPGETRHNLEREEYTVLADLPPPRRLAQRQPGPQAQCSSGGRTH 1300
              SR  A         PPG  RH     +  +    P    LA     P++    GG+  
Sbjct: 2214 ASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAV----PESPGVGGGKAS 2269

Query: 1301 SPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPSRQVTMLPA 1360
             P  +     FG+ R+  E       ++E  +  PS G    L    SP+    +  L  
Sbjct: 2270 EPLLSPPP--FGESRKALEV-----KKEELGASSPSYGPPN-LGFVDSPSSGTHLGGLEL 2321

Query: 1361 K-----QAELT-RRSQAEPPHPWSPEKRPEGDRQLQGSPLPPRTSARTPERELRTQRPLE 1414
            K     +A LT R SQ EP  P     RP+        P P +  A +P       RP  
Sbjct: 2322 KTPDVFKAPLTPRASQVEPQSP-GLGLRPQ-------EPPPAQALAPSPPSHPDIFRPGS 2373

Query: 1415 SGQAGPRQPLGVWQSQEEPPGSQGPHRHLERSWSSQEGGLGPGGWWGCGEPSLGAAKAPE 1474
                  + PL     + +PP  +       RS  S      P                P 
Sbjct: 2374 YTDPYAQPPL---TPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPL 2430

Query: 1475 GAWGGTSREYKESWGQPEAWEEKPTHELPRELGKRSPLTSPPENWGGPAESSQSWHSGTP 1534
             A           +  P+ +   P+   P+     +PL  PP     P     ++ +G+ 
Sbjct: 2431 SAEAFCPSPVTPRFQSPDPYSRPPSR--PQSRDPFAPLHKPPR----PQPPEVAFKAGSL 2484

Query: 1535 TAVGWGAEG---ACPYPRGSERRPELDWRDLLGLLRAPGEGVWARVPSLDWEGLLEL--- 1588
                 GA G   A P     E   ++        +R+PG G +   PS       +    
Sbjct: 2485 AHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGE 2544

Query: 1589 --LQARLPRKD-PAGHRDDLARALGPELGPPGTNDVPEQESHSQPEGWAEATPVNGHSPA 1645
              L+  +P+   P  H  +     GP LG P + +      +  P G +   P +G +  
Sbjct: 2545 PSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSG-SPLGPSSGSTGE 2603

Query: 1646 LQSQSPVQLPS 1656
                SP++ PS
Sbjct: 2604 SYGLSPLRPPS 2614



 Score = 33.9 bits (76), Expect = 1.9
 Identities = 57/278 (20%), Positives = 119/278 (42%), Gaps = 29/278 (10%)

Query: 2009 GLGAPLTEDQQNRLSEEIEKKWQELEKLPLRENKRVPLTALLNQSRGERRGPPSDGHEAL 2068
            G  + L +++Q +L ++  +  Q+L++   ++ ++  L   +   + +++GP    ++AL
Sbjct: 3710 GPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQAL 3769

Query: 2069 EKEVQALRAQ-----LEAWRLQGEAPQ-----------SALRSQEDGHI-PPGYISQEAC 2111
              + Q L        L   +L  + PQ           + L+ Q  G + P G   Q   
Sbjct: 3770 GPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLM 3829

Query: 2112 ERSLAEMESSHQQVMEELQRHHERELQRLQQEKEWLLAEETAATASAIEA-MKKAYQEEL 2170
             +S         Q  + L  H     Q+ QQ+++       A  +   ++ M  + Q +L
Sbjct: 3830 TQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKL 3889

Query: 2171 SRELSKTRSLQQGPDGLRKQHQSDVEALKRELQVLSEQYSQKCLEIGALMRQAEEREHTL 2230
            S +     SLQQ    L++Q Q     L+++ Q+  +Q  Q   +     +Q ++++   
Sbjct: 3890 SAQ--PMGSLQQ----LQQQQQ-----LQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQ 3938

Query: 2231 RRCQQEGQELLRHNQELHGRLSEEIDQLRGFIASQGMG 2268
            +  QQ+ Q+L +  Q+L  +  ++  Q +     Q MG
Sbjct: 3939 QLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMG 3976



 Score = 33.9 bits (76), Expect = 1.9
 Identities = 71/280 (25%), Positives = 96/280 (34%), Gaps = 44/280 (15%)

Query: 1166 IGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLAPSTDSLHGSPVLIPQVCIGHRDAPR 1225
            +G   +   SS P    +PS+   D PG+  ++L            L PQ  +  R    
Sbjct: 4119 LGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNL------------LGPQQPMLERPMQN 4166

Query: 1226 ASSPPRHPPSDLAFLAPSPSPGSSGGSRG---SAPPGETRHNLEREEYTVLADLPPPRRL 1282
             + P   PP       P P   S  G  G       G+ R  L+     VLA  P  R L
Sbjct: 4167 NTGP--QPPK------PGPVLQSGQGLPGVGIMPTVGQLRAQLQ----GVLAKNPQLRHL 4214

Query: 1283 A-QRQPGPQAQCSSGGRTHSPGRAEVERLFGQERRKSEAAGAFQAQDE-GRSQQPSQGQS 1340
            + Q+Q   QA         S    +         + S   G    Q + G    P  G  
Sbjct: 4215 SPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPL 4274

Query: 1341 QLLRRQSSP-APSRQVTMLPAKQAELTRRSQAEPPHPWSPEKRPEGDRQLQGSPLPPRTS 1399
            Q L     P  P R    LPA    L+      P HP  P   P+  +  + S LP    
Sbjct: 4275 QELGAGPRPQGPPR----LPAPPGALSTGPVLGPVHPTPPPSSPQEPK--RPSQLP---- 4324

Query: 1400 ARTPERELRTQRPLESGQAGPRQPLGVWQSQEEPPGSQGP 1439
              +P  +L T+  L     G  +P G   + E PPG   P
Sbjct: 4325 --SPSSQLPTEAQLPPTHPGTPKPQG--PTLEPPPGRVSP 4360



 Score = 33.1 bits (74), Expect = 3.3
 Identities = 23/113 (20%), Positives = 53/113 (46%), Gaps = 15/113 (13%)

Query: 2102 PPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEKEWLLAEETAATASAIEA 2161
            P G + Q   ++ L + +   QQ  ++LQ+  + + Q+LQQ+++              + 
Sbjct: 3893 PMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQ-------------QQ 3939

Query: 2162 MKKAYQEELSRELSKTRSLQQGPDG--LRKQHQSDVEALKRELQVLSEQYSQK 2212
            +++  Q++L ++  + +  QQ       ++Q Q  +  L +   +LS Q  Q+
Sbjct: 3940 LQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQ 3992



 Score = 32.0 bits (71), Expect = 7.4
 Identities = 40/149 (26%), Positives = 55/149 (36%), Gaps = 34/149 (22%)

Query: 983  PGHQSTSRTSSPVYPAAYGAPLTSP-EPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFF 1041
            PG  ST     PV+P     P +SP EP +P        +    A  PP +      P  
Sbjct: 4293 PGALSTGPVLGPVHPTP---PPSSPQEPKRPSQLPSPSSQLPTEAQLPPTH------PGT 4343

Query: 1042 PEPRAPESEPPHHEPPYIPPAVC----------IGHRDAP----------RASSPPRHTQ 1081
            P+P+ P  EPP   P  + PA            +G  D P          ++S  P H  
Sbjct: 4344 PKPQGPTLEPP---PGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLD 4400

Query: 1082 FDPFPFLPDTSDAEHQCQSPQHEPLQLPA 1110
                  +P+ S    + Q P+ EP  L A
Sbjct: 4401 QVNGQVVPEASQLSIK-QEPREEPCALGA 4428


>gi|239742580 PREDICTED: similar to Putative POM121-like protein
            1-like [Homo sapiens]
          Length = 897

 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 156/690 (22%), Positives = 253/690 (36%), Gaps = 75/690 (10%)

Query: 345  PSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTP-CVQQDDPRASSPNRTTQRENSR 403
            PSR +   +   +      P +  PT   Q++ P++  C+    P AS+     +  ++ 
Sbjct: 216  PSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASA----AEVPSTA 271

Query: 404  TSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASS--PSRATRDNPTTSCAQRDNP 461
                ++  P     SS +      P TS   RD  + +S  P+  T  +      +  + 
Sbjct: 272  PVSGKKHRPPGPLFSSSDPL----PATSYHSRDTAQVTSLIPATFTAASRDAGMRRTRSA 327

Query: 462  RASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRA 521
             A+ T++P  +T +N   S     N     PS         + AQR   R ++ S  +R 
Sbjct: 328  PAAATAAPPPSTLNNTSGSLL---NAVDGGPSHFLASATAAARAQRSEVRYNQRSQTSRT 384

Query: 522  TRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQ 581
                   SC +R+   +SS       + +T   Q    R    SS  +    +  T    
Sbjct: 385  R------SCLKRNASSSSS------SHSSTEGLQELKRRRGPASSHCQLAHSSSNT--VS 430

Query: 582  RDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASS--- 638
             D P+A S      +   T+  Q   PR     SP R+    P  + A     +A S   
Sbjct: 431  EDGPQAVSSGHRCENKAGTAPGQTLAPRGG---SP-RSQASRPHINSALYVEDKAISDCR 486

Query: 639  PNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTS-CALRDNPRASSPSRTIQQENPR 697
            P+R +   S   + A    P + +P    QQ+ P++  C     P AS+       E P 
Sbjct: 487  PSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAA------EVPS 540

Query: 698  TSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRAS 757
            T+       R   P  ++    P TS   RD+ + +S          R +  +R  P  S
Sbjct: 541  TAPVSGKKHRPPGPLFSSSDPLPATSSHSRDSAQVTSLIPATFTAASRDAGMRRTRPGTS 600

Query: 758  SPNRT---IQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDN 814
            +P      +    L  +     N     P+         + AQR  +R +   + +Q   
Sbjct: 601  APAAAAAALPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYN---QRSQTSR 657

Query: 815  PRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNP-GTSSSQCCT 873
             R+C+++N   SS +  +  +    +R      C Q   + S +   D P   SS   C 
Sbjct: 658  TRSCLKRNASSSSHSSTEGLQELKRRRGPASSHC-QLAHSSSNTVSEDGPQAVSSGHRCE 716

Query: 874  QK------ENLRPSSPHRSTQWNNPR-NSSPHRTNKDIPWASFPLRPTQ---------SD 917
             K      + L P   +  +Q + PR NS+ H  +K I     P RP+          S 
Sbjct: 717  NKAGTAPGQTLAPRGGYPRSQASRPRINSALHVEDKAISDCR-PSRPSHTLSSLATGASG 775

Query: 918  GPRTS-SPSRSKQSEVPWAS--IALRPTQGDRPQTSS--PSRPAQHDPPQSSFGPTQYNL 972
            GP  S +P+   Q + P +   + L        + SS  P    +H PP   F  +    
Sbjct: 776  GPPVSKAPTMDAQQDRPKSQDCLGLLAPLASAAEVSSTAPVSGKKHRPPGPLFSSSD--- 832

Query: 973  PSRATSSSHNPGHQSTSRTSSPVYPAAYGA 1002
            P  ATSS      Q TS   +P  PA+  A
Sbjct: 833  PLPATSSHSGDSAQDTSLIPAPFTPASRDA 862



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 126/593 (21%), Positives = 213/593 (35%), Gaps = 113/593 (19%)

Query: 332 ASSTQWNTPRASSPSRSTQLDNPRTS---------STQQDNPQTSFPTCTPQRENPRTPC 382
           A+      P + +P+   Q D P++          ++  + P T+    + ++  P  P 
Sbjct: 227 ATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVPSTA--PVSGKKHRPPGPL 284

Query: 383 VQQDDP--RASSPNRTTQRENSRT----SCAQRDNPKASRTSSPNRATRDNPRTSCAQRD 436
               DP    S  +R T +  S      + A RD       S+P  AT   P ++     
Sbjct: 285 FSSSDPLPATSYHSRDTAQVTSLIPATFTAASRDAGMRRTRSAPAAATAAPPPSTLNNTS 344

Query: 437 ----NPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSP 492
               N     PS         + AQR   R ++ S  +R        SC +R+   +SS 
Sbjct: 345 GSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQTSRTR------SCLKRNASSSSSS 398

Query: 493 SRATRDNPTTSCAQRDNPRASRT----SSPNRATRDNPR-------------TSCAQRDN 535
             +T         +R  P +S      SS N  + D P+             T+  Q   
Sbjct: 399 HSSTEG--LQELKRRRGPASSHCQLAHSSSNTVSEDGPQAVSSGHRCENKAGTAPGQTLA 456

Query: 536 PRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATR---------------DNPRTSCA 580
           PR  SP R+    P  + A     +A     P+R +                    T  A
Sbjct: 457 PRGGSP-RSQASRPHINSALYVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDA 515

Query: 581 QRDNPRAS------SPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDN-PRTSCAQRDN 633
           Q+D P++       +P  +  + P+T+     + +  R   P  ++ D  P TS   RD+
Sbjct: 516 QQDRPKSQDCLGLVAPLASAAEVPSTAPV---SGKKHRPPGPLFSSSDPLPATSSHSRDS 572

Query: 634 PRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASS------- 686
            + +S    T   + R +  RR  P  S+P        P T      NP + S       
Sbjct: 573 AQVTSLIPATFTAASRDAGMRRTRPGTSAPAAAAAALPPSTL-----NPTSGSLLNAVDG 627

Query: 687 -PSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRT--IQRDN 743
            PS  +       + AQR + R +  ++T++      SC +R N  +SS + T  +Q   
Sbjct: 628 GPSHFLASAT-AAARAQRSEVRYNQRSQTSRTR----SCLKR-NASSSSHSSTEGLQELK 681

Query: 744 PRTSCAQRDNPRASSPNRTIQQENLR--TSCTRQDNPRTSSPN----------RATRDNP 791
            R   A      A S + T+ ++  +  +S  R +N   ++P           R+    P
Sbjct: 682 RRRGPASSHCQLAHSSSNTVSEDGPQAVSSGHRCENKAGTAPGQTLAPRGGYPRSQASRP 741

Query: 792 RTSCAQRDNLRASSPIRATQQDNPRTCIQQNI----PRSSS----TQQDNPKT 836
           R + A     +A S  R ++  +  + +        P S +     QQD PK+
Sbjct: 742 RINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRPKS 794


>gi|239744133 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 375

 Score = 78.6 bits (192), Expect = 7e-14
 Identities = 94/400 (23%), Positives = 167/400 (41%), Gaps = 45/400 (11%)

Query: 291 RASSTQQEISRASSTQQETSRASST----QEDTPRASSTQEDTPRASSTQWNTPRASSPS 346
           R ++ +Q  + +SS   ++S+ SST       T    S Q     ++S  W + R SS  
Sbjct: 4   RKAACKQHRASSSSCSCQSSQTSSTCSCQSSQTSSTCSCQSSGTSSTSCNWQSSRISSTC 63

Query: 347 RSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSC 406
                    TS + Q +  +S  TC+ Q     +        R SS  R      S TSC
Sbjct: 64  SCQSSGTSSTSCSCQSSETSS--TCSCQSSGTSSTSCSWQFSRTSSTCRCQSSRTSSTSC 121

Query: 407 AQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRT 466
           + +    +SRTSS          TSC+ + +  +S+ S  T    +TSC+ +    +SRT
Sbjct: 122 SCQ----SSRTSS----------TSCSCQSSRTSSTCSCQTSRTSSTSCSYQ----SSRT 163

Query: 467 SSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNP 526
           SS           SC        S   +++R + T SC      ++S TSS + + + + 
Sbjct: 164 SST---------CSCQSSGTSSTSCNWQSSRTSSTCSC------QSSGTSSTSYSCQSSG 208

Query: 527 RTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPR 586
            +S     +   SS + + + + T+S     +   S TS   +++R +   SC    + R
Sbjct: 209 TSSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSWQSSRTSSTCSC---QSSR 265

Query: 587 ASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQD 646
            SS + + + + T+S     +   S TS   +++R +   SC      R SS + + Q  
Sbjct: 266 TSSTSCSCQSSGTSSTCSCQSSGTSSTSCSCQSSRTSSTCSC---QFSRTSSTSCSCQSS 322

Query: 647 SPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASS 686
              ++C+ +    +S+           TSC+ R +  +S+
Sbjct: 323 RTSSTCSCQSSGTSSTSCICWSSGTSSTSCSGRFSGTSST 362



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 97/401 (24%), Positives = 169/401 (42%), Gaps = 43/401 (10%)

Query: 228 ESGLSLERHRSTLTQAS------SMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSP 281
           E   + ++HR++ +  S      S T       T+S  S     T+  +   +  R SS 
Sbjct: 3   ERKAACKQHRASSSSCSCQSSQTSSTCSCQSSQTSSTCSCQSSGTSSTSCNWQSSRISST 62

Query: 282 HRITQRDTSRASSTQQEISRASSTQQETSRASSTQ---EDTPRASSTQEDTPRASSTQWN 338
                  TS  S + Q    +S+   ++S  SST    + +  +S+ +  + R SST  +
Sbjct: 63  CSCQSSGTSSTSCSCQSSETSSTCSCQSSGTSSTSCSWQFSRTSSTCRCQSSRTSSTSCS 122

Query: 339 TPRASSPSRSTQLDNPRTSST-QQDNPQTSFPTCTPQRENPRTPC-VQQDDPRASSPNRT 396
              + + S S    + RTSST      +TS  +C+ Q     + C  Q     ++S N  
Sbjct: 123 CQSSRTSSTSCSCQSSRTSSTCSCQTSRTSSTSCSYQSSRTSSTCSCQSSGTSSTSCNWQ 182

Query: 397 TQRENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCA 456
           + R +S  SC      ++S TSS + + + +  +S     +   SS S + + + T+S  
Sbjct: 183 SSRTSSTCSC------QSSGTSSTSYSCQSSGTSSTCSCQSSGTSSTSCSCQSSGTSSTC 236

Query: 457 QRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTS 516
              +   S TS   +++R +   SC    + R SS S + + + T+S     +   S TS
Sbjct: 237 SCQSSGTSSTSCSWQSSRTSSTCSC---QSSRTSSTSCSCQSSGTSSTCSCQSSGTSSTS 293

Query: 517 SPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRA--TRDN 574
              +++R +   SC        S   +++R + T SC      ++S TSS +    +   
Sbjct: 294 CSCQSSRTSSTCSCQFSRTSSTSCSCQSSRTSSTCSC------QSSGTSSTSCICWSSGT 347

Query: 575 PRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSS 615
             TSC+ R +  +S           TSC    N R+S TSS
Sbjct: 348 SSTSCSGRFSGTSS-----------TSC----NCRSSGTSS 373



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 86/398 (21%), Positives = 171/398 (42%), Gaps = 34/398 (8%)

Query: 478 RTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPR 537
           + +C Q    RASS S + + + T+S     + + S T S   +   +  TSC  + +  
Sbjct: 5   KAACKQH---RASSSSCSCQSSQTSSTCSCQSSQTSSTCSCQSSGTSS--TSCNWQSSRI 59

Query: 538 ASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDN 597
           +S+ +  +    +TSC+ + +  +S  S  +  T     TSC+ + +  +S+    +   
Sbjct: 60  SSTCSCQSSGTSSTSCSCQSSETSSTCSCQSSGTSS---TSCSWQFSRTSSTCRCQSSRT 116

Query: 598 PTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDD 657
            +TSC+ + + R S TS   +++R +   SC      R SS + + Q     ++C+ +  
Sbjct: 117 SSTSCSCQSS-RTSSTSCSCQSSRTSSTCSC---QTSRTSSTSCSYQSSRTSSTCSCQSS 172

Query: 658 PRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQ 717
              SS +   Q     ++C+ + +   SS S + Q     ++C+ +     SS + + Q 
Sbjct: 173 G-TSSTSCNWQSSRTSSTCSCQSSG-TSSTSYSCQSSGTSSTCSCQSSG-TSSTSCSCQS 229

Query: 718 ENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDN 777
               ++C+ + +  +S            TSC+ + + R SS           TSC+ Q +
Sbjct: 230 SGTSSTCSCQSSGTSS------------TSCSWQSS-RTSSTCSCQSSRTSSTSCSCQSS 276

Query: 778 PRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTS 837
             +S+ +  +     TSC+ + +  +S+      + +  +C  Q+   SS+    +  TS
Sbjct: 277 GTSSTCSCQSSGTSSTSCSCQSSRTSSTCSCQFSRTSSTSCSCQSSRTSSTCSCQSSGTS 336

Query: 838 -----CTKRDNLRPTCTQR-DRTQSFSFQRDNPGTSSS 869
                C        +C+ R   T S S    + GTSS+
Sbjct: 337 STSCICWSSGTSSTSCSGRFSGTSSTSCNCRSSGTSST 374



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 93/364 (25%), Positives = 149/364 (40%), Gaps = 47/364 (12%)

Query: 214 GGRSAGQHWARLRGESGLSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTR 273
           G  S   +W   R  S  S +   ++ T  S  +       T+S  S     T+  + + 
Sbjct: 46  GTSSTSCNWQSSRISSTCSCQSSGTSSTSCSCQSSE-----TSSTCSCQSSGTSSTSCSW 100

Query: 274 EIPRASSPHRITQRDTSRASSTQQEISRASSTQQ--ETSRASSTQEDTPRASSTQEDTPR 331
           +  R SS  R     TS  S + Q  SR SST    ++SR SST        S Q  T R
Sbjct: 101 QFSRTSSTCRCQSSRTSSTSCSCQS-SRTSSTSCSCQSSRTSST-------CSCQ--TSR 150

Query: 332 ASSTQWNTPRASSPSRSTQLDNPRTSST-QQDNPQTSFPTCTPQRENPRTPCVQQDDPRA 390
            SST            S    + RTSST    +  TS  +C  Q     + C  Q     
Sbjct: 151 TSST------------SCSYQSSRTSSTCSCQSSGTSSTSCNWQSSRTSSTCSCQSS-GT 197

Query: 391 SSPNRTTQRENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDN 450
           SS + + Q   + ++C+ + +  +S TS   +++  +   SC        S   +++R +
Sbjct: 198 SSTSYSCQSSGTSSTCSCQSSGTSS-TSCSCQSSGTSSTCSCQSSGTSSTSCSWQSSRTS 256

Query: 451 PTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNP 510
            T SC      ++SRTSS + + + +  +S     +   SS S + + + T+S       
Sbjct: 257 STCSC------QSSRTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSCQSSRTSSTCSCQFS 310

Query: 511 RASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQR--------DNPRAS 562
           R S TS   +++R +   SC Q     ++S    +    +TSC+ R         N R+S
Sbjct: 311 RTSSTSCSCQSSRTSSTCSC-QSSGTSSTSCICWSSGTSSTSCSGRFSGTSSTSCNCRSS 369

Query: 563 RTSS 566
            TSS
Sbjct: 370 GTSS 373



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 65/277 (23%), Positives = 107/277 (38%), Gaps = 29/277 (10%)

Query: 625 RTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRA 684
           + +C Q    RASS + + Q     ++C+ +   + SS           TSC  + + R 
Sbjct: 5   KAACKQH---RASSSSCSCQSSQTSSTCSCQSS-QTSSTCSCQSSGTSSTSCNWQSS-RI 59

Query: 685 SSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNP 744
           SS           TSC+ +     SS           TSC+ + + R SS  R       
Sbjct: 60  SSTCSCQSSGTSSTSCSCQSS-ETSSTCSCQSSGTSSTSCSWQFS-RTSSTCRCQSSRTS 117

Query: 745 RTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRAS 804
            TSC+ + +  +S            TSC+ Q +  +S+ +  T     TSC+ + +  +S
Sbjct: 118 STSCSCQSSRTSS------------TSCSCQSSRTSSTCSCQTSRTSSTSCSYQSSRTSS 165

Query: 805 SPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCT----KRDNLRPTCT-QRDRTQSFSF 859
           +    +   +  +C  Q+   SS+    +  TS T    +      TC+ Q   T S S 
Sbjct: 166 TCSCQSSGTSSTSCNWQSSRTSSTCSCQSSGTSSTSYSCQSSGTSSTCSCQSSGTSSTSC 225

Query: 860 QRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSS 896
              + GTSS+  C         +   S  W + R SS
Sbjct: 226 SCQSSGTSSTCSCQSS-----GTSSTSCSWQSSRTSS 257


>gi|239742514 PREDICTED: similar to Putative POM121-like protein
            1-like [Homo sapiens]
          Length = 896

 Score = 77.4 bits (189), Expect = 2e-13
 Identities = 198/863 (22%), Positives = 309/863 (35%), Gaps = 146/863 (16%)

Query: 244  SSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRAS--STQQEISR 301
            S   P  GP  T   A  ++    Q + T     ++  + I+   +S       +Q    
Sbjct: 41   SPFVPRPGPLQTDLHAQSSEIRYNQTSQTSWTSSSTKRNAISSSYSSTGGLPGLKQRRGP 100

Query: 302  ASSTQQETSRASST-QEDTPRA-SSTQEDTPRASST---QWNTPRASSPSRSTQLDNPRT 356
            ASS  Q T   S T  ED P+A SS      +A+ T   Q   PR  SP   +Q   PR 
Sbjct: 101  ASSRCQLTLSYSKTVSEDRPQAVSSGHTRCEKAADTAPGQTLAPRGGSPR--SQASRPRR 158

Query: 357  SSTQQDNPQTSFPTCTPQRENPRTPCVQQD---DPRASSP--NRTTQRENSRTSCAQRDN 411
                    +   P   P           +D   + +A+    N     E+   S  +   
Sbjct: 159  RKIPLLPSRRGEPLMMPPPLELGYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSR 218

Query: 412  PKASRTSSPNRATRDNP----RTSCAQRDNPRA----------SSPSRATRDNPTTSCAQ 457
            P  + +S    A+   P     T  AQ+D P++          +S +  +   P +   Q
Sbjct: 219  PSHTLSSLATGASGGPPVSKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKQ 278

Query: 458  RDNPRASRTSSPNRATRDNPRTSC------------AQRDNPRASSPSRATRDNPTTSCA 505
            R       +S P  AT  + R S             A RD     +  R TR  P  + A
Sbjct: 279  RPPGPLFSSSDPLPATSSHSRDSAQVTSMIPAPFTAASRD-----AGMRRTRSAPAAAAA 333

Query: 506  QRDNPRASRTSS---------PNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQR 556
                   + TS          P+         + AQR   R +  ++ +R   T SC +R
Sbjct: 334  APPPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISR---TRSCLKR 390

Query: 557  DNPRASRTSS---PNRATRDNPRTSCAQRDNPRASSPNRATRDNPT------TSCAQRDN 607
            +   +S +S+   P    R  P +S  Q  +   SS    + D P       T C +R +
Sbjct: 391  NASSSSHSSTEGLPELKRRRGPASSHCQLAH---SSSKTVSEDGPQAVSSGHTRCEKRAD 447

Query: 608  PRASRTSSPN----RATRDNPRTSCAQRDNPRASS---PNRTTQQDSPRTSCARRDDPRA 660
                +T +P     R+    P  + A     +A S   P+R +   S   + A R  P +
Sbjct: 448  TAPGQTLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPVS 507

Query: 661  SSPNRTIQQENPRT-SCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQEN 719
             +P    QQ+ P++  C     P AS+       E P T+       R   P  ++    
Sbjct: 508  KAPTMDAQQDRPKSQDCLGLLAPLASA------AELPSTAPVSGKKHRPPGPLFSSSDPL 561

Query: 720  PRTSCARRDNPR----------ASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLR 769
            P TS   RD+ +          A+SR+  ++R  P TS        A+ P  T+      
Sbjct: 562  PATSSHSRDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAA--AAAAPPPSTL------ 613

Query: 770  TSCTRQDNPRTSSPNRATRDNP--------RTSCAQRDNLRASSPIRATQQDNPRTCIQQ 821
                   NP + S   A  + P          + A+R  +R +   + +Q    R+C+++
Sbjct: 614  -------NPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYN---QRSQTSRTRSCLKR 663

Query: 822  NIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSS---QC----CTQ 874
            N   SS +  +  +    +R      C Q   + S +   D P   SS   +C       
Sbjct: 664  NASSSSHSSTEGLQELKRRRGPASSHC-QLALSSSNTVSEDGPQAVSSRDTRCEKADTAP 722

Query: 875  KENLRPSSPHRSTQWNNPR-NSSPHRTNKDIPWASFPLRPTQ---------SDGPRTS-S 923
             + L P      +Q + PR NS+ H  +K I     P RP+          S GP  S +
Sbjct: 723  GQTLAPRGGSPRSQASRPRINSALHVEDKAISDCR-PSRPSHTLSSLATGASGGPPVSKA 781

Query: 924  PSRSKQSEVPWAS--IALRPTQGDRPQTSS--PSRPAQHDPPQSSFGPTQYNLPSRATSS 979
            P+   Q + P +   + L        + SS  P    +H PP   F  +    P  ATSS
Sbjct: 782  PTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKKHRPPGPLFSSSD---PLPATSS 838

Query: 980  SHNPGHQSTSRTSSPVYPAAYGA 1002
                  Q TS   +P  PA+  A
Sbjct: 839  HSGDSAQDTSLIPAPFTPASRDA 861



 Score = 37.0 bits (84), Expect = 0.23
 Identities = 172/770 (22%), Positives = 248/770 (32%), Gaps = 99/770 (12%)

Query: 680  DNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTI 739
            D P+A S   T  ++   T+  Q   PR  SP   +Q   PR    RR  P   SR    
Sbjct: 118  DRPQAVSSGHTRCEKAADTAPGQTLAPRGGSPR--SQASRPR----RRKIPLLPSRRGEP 171

Query: 740  QRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNP----RTSSPNRATRDNPRTSC 795
                P      R         +    + + ++   +D      R S P+  T  +  T  
Sbjct: 172  LMMPPPLELGYRVTAEDLHLEKQAAFQRINSALHVEDKAISDCRPSRPSH-TLSSLATGA 230

Query: 796  AQRDNLRASSPIRATQQDNPRT--CIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDR 853
            +    + + +P    QQD P++  C+    P +S+ +  +      K+        QR  
Sbjct: 231  SGGPPV-SKAPTMDAQQDRPKSQDCLGLVAPLASAAEVSSTAPVSGKK--------QRPP 281

Query: 854  TQSFSFQRDNPGTSS-SQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLR 912
               FS     P TSS S+   Q  ++ P+ P  +      R++   RT +  P A+    
Sbjct: 282  GPLFSSSDPLPATSSHSRDSAQVTSMIPA-PFTAAS----RDAGMRRT-RSAPAAAAAAP 335

Query: 913  PTQSDGPRTSS--------PSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDPPQSS 964
            P  +  P + S        PS    S    A       + ++    S +R        SS
Sbjct: 336  PPSTLNPTSGSLLNAVDGGPSHFLASATAAARAQRSEVRYNQRSQISRTRSCLKRNASSS 395

Query: 965  FGPTQYNLPS----RATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGH 1020
               +   LP     R  +SSH     S+S+T S   P A  +  T  E          G 
Sbjct: 396  SHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGHTRCEKRADTAP---GQ 452

Query: 1021 RDAPRASSPPRYLQ--HDPFPFFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPR 1078
              APR  SP       H       E +A     P   P +   ++  G    P  S  P 
Sbjct: 453  TLAPRGGSPRSQASRPHINSALHVEDKAISDCRPSR-PSHTLSSLATGASRGPPVSKAP- 510

Query: 1079 HTQFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQD 1138
                        T DA+ Q +    + L L AP+         A    ++   P  LF  
Sbjct: 511  ------------TMDAQ-QDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSS 557

Query: 1139 ---LPRASTESLVPSMDSLHECPHIPTPVCIGHRDA------PSFSSPPRQAPEPSLFFQ 1189
               LP  S+ S     DS      IP P     RDA      P  S+P   A  P     
Sbjct: 558  SDPLPATSSHS----RDSAQVTSMIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTL 613

Query: 1190 DPPGTSM---------ESLAPSTDSLHG--SPVLIPQVCIGHRDAP----RASSPPRHPP 1234
            +P   S+           LA +T +     S V   Q     R        ASS      
Sbjct: 614  NPTSGSLLNAVDEGPSHFLASATAAARARRSQVRYNQRSQTSRTRSCLKRNASSSSHSST 673

Query: 1235 SDLAFLAPSPSPGSSG-----GSRGSAPPGETRHNLEREEYTVLADLPPPRRLAQRQPGP 1289
              L  L     P SS       S  +      +    R+     AD  P + LA R   P
Sbjct: 674  EGLQELKRRRGPASSHCQLALSSSNTVSEDGPQAVSSRDTRCEKADTAPGQTLAPRGGSP 733

Query: 1290 QAQCSSGGRTHSPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQSSP 1349
            ++Q S   R        VE     + R S  +    +   G S  P   ++  +  Q   
Sbjct: 734  RSQAS---RPRINSALHVEDKAISDCRPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDR 790

Query: 1350 APSRQVTMLPAKQAELTRRSQAEPPHPWSPEKRPEGDRQLQGSPLPPRTS 1399
              S+    L A  A     S   P      + RP G       PLP  +S
Sbjct: 791  PKSQDCLGLVAPLASAAEVSSTAPVS--GKKHRPPGPLFSSSDPLPATSS 838



 Score = 36.2 bits (82), Expect = 0.39
 Identities = 90/422 (21%), Positives = 156/422 (36%), Gaps = 52/422 (12%)

Query: 146 TSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPRE-GPRADSSQRAPSLLTRSPVGGDAA 204
           +S+SS+     ++R+   A S  +LA    +   E GP+A SS       TR     D A
Sbjct: 395 SSHSSTEGLPELKRRRGPASSHCQLAHSSSKTVSEDGPQAVSSGH-----TRCEKRADTA 449

Query: 205 -GQKKEDTGGGGRSAGQHWARLRGESGLSLERH--------RSTLTQASSMTPHS-GPRS 254
            GQ     GG  RS     +R    S L +E          R + T +S  T  S GP  
Sbjct: 450 PGQTLAPRGGSPRSQA---SRPHINSALHVEDKAISDCRPSRPSHTLSSLATGASRGPPV 506

Query: 255 TTSQASPAQRDT----------AQAASTREIPRASSPHRITQRDTSRASSTQQEISRASS 304
           + +    AQ+D           A  AS  E+P  +       R      S+   +   SS
Sbjct: 507 SKAPTMDAQQDRPKSQDCLGLLAPLASAAELPSTAPVSGKKHRPPGPLFSSSDPLPATSS 566

Query: 305 TQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSS---TQQ 361
             +++++ +S     P  +++++   R +    + P A++ +      NP + S      
Sbjct: 567 HSRDSAQVTS-MIPAPFTAASRDAGMRRTRPGTSAPAAAAAAPPPSTLNPTSGSLLNAVD 625

Query: 362 DNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRT-SCAQRDNPKASRTSSP 420
           + P     + T                R S      + + SRT SC +R+   +S +S+ 
Sbjct: 626 EGPSHFLASATAAAR-----------ARRSQVRYNQRSQTSRTRSCLKRNASSSSHSSTE 674

Query: 421 NRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTS 480
                   R   +       SS +  + D P  + + RD       ++P +       + 
Sbjct: 675 GLQELKRRRGPASSHCQLALSSSNTVSEDGPQ-AVSSRDTRCEKADTAPGQTLAPRGGSP 733

Query: 481 CAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNP----RTSCAQRDNP 536
            +Q   PR +S +    D   + C +   P  + +S    A+   P     T  AQ+D P
Sbjct: 734 RSQASRPRINS-ALHVEDKAISDC-RPSRPSHTLSSLATGASGGPPVSKAPTMDAQQDRP 791

Query: 537 RA 538
           ++
Sbjct: 792 KS 793


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.125    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 118,288,174
Number of Sequences: 37866
Number of extensions: 7278589
Number of successful extensions: 51745
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 224
Number of HSP's successfully gapped in prelim test: 2484
Number of HSP's that attempted gapping in prelim test: 28960
Number of HSP's gapped (non-prelim): 17261
length of query: 2365
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2246
effective length of database: 13,741,464
effective search space: 30863328144
effective search space used: 30863328144
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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