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Search of human proteins with 86793036
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|86793036 complement receptor 1 isoform F precursor [Homo
sapiens]
(2039 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|86793036 complement receptor 1 isoform F precursor [Homo sapi... 4396 0.0
gi|86793109 complement receptor 1 isoform S precursor [Homo sapi... 4204 0.0
gi|148922949 complement component (3b/4b) receptor 1-like [Homo ... 778 0.0
gi|148886654 polydom [Homo sapiens] 685 0.0
gi|42544177 complement component (3d/Epstein Barr virus) recepto... 603 e-172
gi|54792123 complement component (3d/Epstein Barr virus) recepto... 603 e-172
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 401 e-111
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 399 e-110
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 399 e-110
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 358 2e-98
gi|62739186 complement factor H isoform a precursor [Homo sapiens] 315 4e-85
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 282 3e-75
gi|4502503 complement component 4 binding protein, alpha chain p... 221 6e-57
gi|157419154 selectin P precursor [Homo sapiens] 192 3e-48
gi|168693643 decay accelerating factor for complement isoform 2 ... 168 4e-41
gi|10835143 decay accelerating factor for complement isoform 1 p... 168 4e-41
gi|27502413 CD46 antigen, complement regulatory protein isoform ... 159 3e-38
gi|27502402 CD46 antigen, complement regulatory protein isoform ... 159 3e-38
gi|27502425 CD46 antigen, complement regulatory protein isoform ... 159 3e-38
gi|27502423 CD46 antigen, complement regulatory protein isoform ... 159 3e-38
gi|187960042 selectin E precursor [Homo sapiens] 155 5e-37
gi|27502421 CD46 antigen, complement regulatory protein isoform ... 154 6e-37
gi|27502417 CD46 antigen, complement regulatory protein isoform ... 154 6e-37
gi|27502415 CD46 antigen, complement regulatory protein isoform ... 154 6e-37
gi|27502407 CD46 antigen, complement regulatory protein isoform ... 154 6e-37
gi|24432108 CD46 antigen, complement regulatory protein isoform ... 154 6e-37
gi|27502411 CD46 antigen, complement regulatory protein isoform ... 154 1e-36
gi|27502409 CD46 antigen, complement regulatory protein isoform ... 154 1e-36
gi|27502405 CD46 antigen, complement regulatory protein isoform ... 154 1e-36
gi|27502419 CD46 antigen, complement regulatory protein isoform ... 153 1e-36
>gi|86793036 complement receptor 1 isoform F precursor [Homo sapiens]
Length = 2039
Score = 4396 bits (11402), Expect = 0.0
Identities = 2039/2039 (100%), Positives = 2039/2039 (100%)
Query: 1 MGASSPRSPEPVGPPAPGLPFCCGGSLLAVVVLLALPVAWGQCNAPEWLPFARPTNLTDE 60
MGASSPRSPEPVGPPAPGLPFCCGGSLLAVVVLLALPVAWGQCNAPEWLPFARPTNLTDE
Sbjct: 1 MGASSPRSPEPVGPPAPGLPFCCGGSLLAVVVLLALPVAWGQCNAPEWLPFARPTNLTDE 60
Query: 61 FEFPIGTYLNYECRPGYSGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG 120
FEFPIGTYLNYECRPGYSGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG
Sbjct: 61 FEFPIGTYLNYECRPGYSGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG 120
Query: 121 IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFIST 180
IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFIST
Sbjct: 121 IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFIST 180
Query: 181 NRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTP 240
NRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTP
Sbjct: 181 NRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTP 240
Query: 241 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 300
PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP
Sbjct: 241 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 300
Query: 301 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDD 360
PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDD
Sbjct: 301 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDD 360
Query: 361 FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIF 420
FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIF
Sbjct: 361 FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIF 420
Query: 421 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 480
CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW
Sbjct: 421 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 480
Query: 481 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNL 540
SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNL
Sbjct: 481 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNL 540
Query: 541 VWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGN 600
VWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGN
Sbjct: 541 VWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGN 600
Query: 601 AAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGE 660
AAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGE
Sbjct: 601 AAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGE 660
Query: 661 PSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGF 720
PSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGF
Sbjct: 661 PSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGF 720
Query: 721 VMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY 780
VMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY
Sbjct: 721 VMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY 780
Query: 781 DLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGF 840
DLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGF
Sbjct: 781 DLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGF 840
Query: 841 QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTC 900
QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTC
Sbjct: 841 QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTC 900
Query: 901 DPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNA 960
DPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNA
Sbjct: 901 DPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNA 960
Query: 961 SDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITD 1020
SDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITD
Sbjct: 961 SDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITD 1020
Query: 1021 IQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFIST 1080
IQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFIST
Sbjct: 1021 IQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFIST 1080
Query: 1081 NRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTP 1140
NRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTP
Sbjct: 1081 NRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTP 1140
Query: 1141 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 1200
PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP
Sbjct: 1141 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 1200
Query: 1201 PEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDD 1260
PEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDD
Sbjct: 1201 PEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDD 1260
Query: 1261 FLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIF 1320
FLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIF
Sbjct: 1261 FLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIF 1320
Query: 1321 CPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVW 1380
CPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVW
Sbjct: 1321 CPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVW 1380
Query: 1381 SSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCL 1440
SSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCL
Sbjct: 1381 SSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCL 1440
Query: 1441 ENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLV 1500
ENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLV
Sbjct: 1441 ENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLV 1500
Query: 1501 SGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFEL 1560
SGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFEL
Sbjct: 1501 SGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFEL 1560
Query: 1561 VGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQ 1620
VGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQ
Sbjct: 1561 VGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQ 1620
Query: 1621 PGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCE 1680
PGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCE
Sbjct: 1621 PGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCE 1680
Query: 1681 PSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCD 1740
PSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCD
Sbjct: 1681 PSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCD 1740
Query: 1741 EGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEIS 1800
EGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEIS
Sbjct: 1741 EGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEIS 1800
Query: 1801 YACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYI 1860
YACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYI
Sbjct: 1801 YACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYI 1860
Query: 1861 GGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMNGISK 1920
GGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMNGISK
Sbjct: 1861 GGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMNGISK 1920
Query: 1921 ELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKCTSRTHDALIVGTLSG 1980
ELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKCTSRTHDALIVGTLSG
Sbjct: 1921 ELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKCTSRTHDALIVGTLSG 1980
Query: 1981 TIFFILLIIFLSWIILKHRKGNNAHENPKEVAIHLHSQGGSSVHPRTLQTNEENSRVLP 2039
TIFFILLIIFLSWIILKHRKGNNAHENPKEVAIHLHSQGGSSVHPRTLQTNEENSRVLP
Sbjct: 1981 TIFFILLIIFLSWIILKHRKGNNAHENPKEVAIHLHSQGGSSVHPRTLQTNEENSRVLP 2039
>gi|86793109 complement receptor 1 isoform S precursor [Homo sapiens]
Length = 2489
Score = 4204 bits (10904), Expect = 0.0
Identities = 1950/1999 (97%), Positives = 1962/1999 (98%)
Query: 41 GQCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYSGRPFSIICLKNSVWTGAKDRCR 100
G C AP+ FA+ T+ +FPIGT L YECRP Y GRPFSI CL N VW+ KD C+
Sbjct: 491 GHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCK 550
Query: 101 RKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPI 160
RKSC+ PPDPVNGMVHVI IQ GS+I YSCT G+RLIG SSA CI+SG+ W + PI
Sbjct: 551 RKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPI 610
Query: 161 CDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDD 220
C RIPCGLPPTI NGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDD
Sbjct: 611 CQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDD 670
Query: 221 QVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 280
QVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC
Sbjct: 671 QVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 730
Query: 281 QALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRC 340
QALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRC
Sbjct: 731 QALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRC 790
Query: 341 TPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYC 400
TPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYC
Sbjct: 791 TPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYC 850
Query: 401 VLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSF 460
VLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSF
Sbjct: 851 VLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSF 910
Query: 461 DLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLK 520
DLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLK
Sbjct: 911 DLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLK 970
Query: 521 YECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYS 580
YECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYS
Sbjct: 971 YECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYS 1030
Query: 581 CTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSV 640
CTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSV
Sbjct: 1031 CTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSV 1090
Query: 641 VTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVS 700
VTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVS
Sbjct: 1091 VTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVS 1150
Query: 701 DNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQ 760
DNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQ
Sbjct: 1151 DNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQ 1210
Query: 761 RDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRV 820
RDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRV
Sbjct: 1211 RDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRV 1270
Query: 821 LFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNG 880
LFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNG
Sbjct: 1271 LFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNG 1330
Query: 881 RHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGIL 940
RHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGIL
Sbjct: 1331 RHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGIL 1390
Query: 941 GHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCK 1000
GHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCK
Sbjct: 1391 GHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCK 1450
Query: 1001 RKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPI 1060
RKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPI
Sbjct: 1451 RKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPI 1510
Query: 1061 CQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDD 1120
CQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDD
Sbjct: 1511 CQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDD 1570
Query: 1121 QVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 1180
QVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC
Sbjct: 1571 QVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 1630
Query: 1181 QALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHC 1240
QALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHC
Sbjct: 1631 QALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHC 1690
Query: 1241 TPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHC 1300
TPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHC
Sbjct: 1691 TPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHC 1750
Query: 1301 VLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTF 1360
VLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTF
Sbjct: 1751 VLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTF 1810
Query: 1361 NLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGT 1420
NLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGT
Sbjct: 1811 NLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGT 1870
Query: 1421 SLNYECRPGYFGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTV 1480
SLNYECRPGYFGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTV
Sbjct: 1871 SLNYECRPGYFGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTV 1930
Query: 1481 NYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHN 1540
NYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHN
Sbjct: 1931 NYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHN 1990
Query: 1541 GTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAI 1600
GTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAI
Sbjct: 1991 GTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAI 2050
Query: 1601 RVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGE 1660
RVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGE
Sbjct: 2051 RVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGE 2110
Query: 1661 HTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPH 1720
HTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPH
Sbjct: 2111 HTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPH 2170
Query: 1721 GRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAI 1780
GRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAI
Sbjct: 2171 GRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAI 2230
Query: 1781 LNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRC 1840
LNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRC
Sbjct: 2231 LNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRC 2290
Query: 1841 ELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQL 1900
ELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQL
Sbjct: 2291 ELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQL 2350
Query: 1901 DHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDP 1960
DHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDP
Sbjct: 2351 DHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDP 2410
Query: 1961 PLAKCTSRTHDALIVGTLSGTIFFILLIIFLSWIILKHRKGNNAHENPKEVAIHLHSQGG 2020
PLAKCTSRTHDALIVGTLSGTIFFILLIIFLSWIILKHRKGNNAHENPKEVAIHLHSQGG
Sbjct: 2411 PLAKCTSRTHDALIVGTLSGTIFFILLIIFLSWIILKHRKGNNAHENPKEVAIHLHSQGG 2470
Query: 2021 SSVHPRTLQTNEENSRVLP 2039
SSVHPRTLQTNEENSRVLP
Sbjct: 2471 SSVHPRTLQTNEENSRVLP 2489
Score = 3655 bits (9479), Expect = 0.0
Identities = 1708/1972 (86%), Positives = 1777/1972 (90%), Gaps = 15/1972 (0%)
Query: 1 MGASSPRSPEPVGPPAPGLPFCCGGSLLAVVVLLALPVAWGQCNAPEWLPFARPTNLTDE 60
MGASSPRSPEPVGPPAPGLPFCCGGSLLAVVVLLALPVAWGQCNAPEWLPFARPTNLTDE
Sbjct: 1 MGASSPRSPEPVGPPAPGLPFCCGGSLLAVVVLLALPVAWGQCNAPEWLPFARPTNLTDE 60
Query: 61 FEFPIGTYLNYECRPGYSGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG 120
FEFPIGTYLNYECRPGYSGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG
Sbjct: 61 FEFPIGTYLNYECRPGYSGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG 120
Query: 121 IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFIST 180
IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFIST
Sbjct: 121 IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFIST 180
Query: 181 NRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTP 240
NRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTP
Sbjct: 181 NRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTP 240
Query: 241 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 300
PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP
Sbjct: 241 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 300
Query: 301 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDD 360
PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDD
Sbjct: 301 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDD 360
Query: 361 FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIF 420
FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIF
Sbjct: 361 FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIF 420
Query: 421 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 480
CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW
Sbjct: 421 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 480
Query: 481 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNL 540
SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNL
Sbjct: 481 SSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNL 540
Query: 541 VWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGN 600
VWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGN
Sbjct: 541 VWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGN 600
Query: 601 AAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGE 660
AAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGE
Sbjct: 601 AAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGE 660
Query: 661 PSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGF 720
PSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGF
Sbjct: 661 PSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGF 720
Query: 721 VMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY 780
VMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY
Sbjct: 721 VMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY 780
Query: 781 DLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGF 840
DLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGF
Sbjct: 781 DLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGF 840
Query: 841 QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTC 900
QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGK VNYTC
Sbjct: 841 QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTC 900
Query: 901 DPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNA 960
DPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNA
Sbjct: 901 DPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNA 960
Query: 961 SDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITD 1020
SDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITD
Sbjct: 961 SDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITD 1020
Query: 1021 IQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFIST 1080
IQVGSRINYSCTTGHRLIGHSSAECILSGN AHWSTKPPICQRIPCGLPPTIANGDFIST
Sbjct: 1021 IQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFIST 1080
Query: 1081 NRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTP 1140
NRENFHYGSVVTYRCN GS GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTP
Sbjct: 1081 NRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTP 1140
Query: 1141 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 1200
PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP
Sbjct: 1141 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPP 1200
Query: 1201 PEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDD 1260
P++LH E T +DNFSPGQEVFYSCEPGYDLRGAAS+ CTPQGDWSP AP C VKSCDD
Sbjct: 1201 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDD 1260
Query: 1261 FLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIF 1320
F+GQL +GRVLFP+NLQLGAKV FVCDEGF+LKGSS S+CVL GM SLWN+SVPVCE IF
Sbjct: 1261 FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIF 1320
Query: 1321 CPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVW 1380
CP+PP I NGRHTG P P+GK ++YTCDPHPDRG +F+LIGESTIRCTSDP GNGVW
Sbjct: 1321 CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 1380
Query: 1381 SSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCL 1440
SSPAPRC + GHC+ P+ F FA N +FP+GTSL YECRP Y+G+ FSI+CL
Sbjct: 1381 SSPAPRCGI---LGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCL 1437
Query: 1441 ENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLV 1500
+NLVWSS +D C+RKSC PP+P NGMVH+ TD Q GS +NYSC G RLIG S C++
Sbjct: 1438 DNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL 1497
Query: 1501 SGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFEL 1560
SGN W K PIC+ I C PPTI+NGDF S NR +FH G+VVTY+C+ G G ++FEL
Sbjct: 1498 SGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFEL 1557
Query: 1561 VGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQ 1620
VGE SIYCTS DDQVG+WS P P+CI NKCT P VEN I V NRS F+L E++ FRCQ
Sbjct: 1558 VGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQ 1617
Query: 1621 PGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCE 1680
PGFVM G V+CQ +W P+LP CSRVCQPPPEILHGEHT SHQDNFSPGQEVFYSCE
Sbjct: 1618 PGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCE 1677
Query: 1681 PSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCD 1740
P YDLRGAASLHCTPQGDWSPEAPRC VKSCDDFLGQLPHGRVL PLNLQLGAKVSFVCD
Sbjct: 1678 PGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCD 1737
Query: 1741 EGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEIS 1800
EGFRLKG S SHCVL GM++LWN+SVPVCE IFCPNPPAILNGRHTGTP GDIPYGKEIS
Sbjct: 1738 EGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEIS 1797
Query: 1801 YACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAA-CPHPPKIQNGHY 1859
Y CD HPDRGMTFNLIGES+IRCTSDP GNGVWSSPAPRCELSV A C P +
Sbjct: 1798 YTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASP 1857
Query: 1860 IGGHVSLYLP-GMTISYICDPGYLLVGKGF-IFCTDQGIWSQLDHYCKEVNCSFPLF-MN 1916
P G +++Y C PGY GK F I C + +WS ++ C+ +C P N
Sbjct: 1858 TIPINDFEFPVGTSLNYECRPGYF--GKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFN 1915
Query: 1917 GISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDR---WDPPLAKC 1965
G+ + + +G V C +G+ L GSP + C WD C
Sbjct: 1916 GM---VHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPIC 1964
Score = 701 bits (1809), Expect = 0.0
Identities = 331/571 (57%), Positives = 400/571 (70%), Gaps = 18/571 (3%)
Query: 36 LPVAWGQCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYSGRPFSIICLKNSVWTGA 95
L V G C PE PFA PT ++FEFP+GT LNYECRPGY G+ FSI CL+N VW+
Sbjct: 1839 LSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSV 1898
Query: 96 KDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWD 155
+D CRRKSC PP+P NGMVH+ QFGS + YSC +G+RLIGS S TC++SG+ V WD
Sbjct: 1899 EDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWD 1958
Query: 156 NETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYC 215
+ PIC+ I C PPTI+NGDF S NR +FH G+VVTY+C+ G G ++FELVGE SIYC
Sbjct: 1959 KKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYC 2018
Query: 216 TSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP 275
TS DDQVG+WS P P+CI NKCT P VEN I V NRS F+L E++ FRCQPGFVM G
Sbjct: 2019 TSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGS 2078
Query: 276 RRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 335
V+CQ +W P+LP CSRVCQPPP++LH E T +DNFSPGQEVFYSCEP YDLRGA
Sbjct: 2079 HTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGA 2138
Query: 336 ASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGS 395
AS+ CTPQGDWSP AP C VKSCDDF+GQL +GRVL P+NLQLGAKV FVCDEGF+LKG
Sbjct: 2139 ASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGR 2198
Query: 396 SASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPD 455
SAS+CVLAGM++LWNSSVPVCEQIFCP+PP I NGRHTG P P+GK ++Y CD HPD
Sbjct: 2199 SASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPD 2258
Query: 456 RGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC--GILGHCQAP-----DHFLFAKLKTQT 508
RG +F+LIGES+IRCTSDPQGNGVWSSPAPRC + C P H++
Sbjct: 2259 RGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGG------ 2312
Query: 509 NASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTP--PDPVNGM 564
+ S + G ++ Y C P Y G+ F I C D +WS CK +C P + ++
Sbjct: 2313 HVSLYLPGMTISYICDPGYLLVGKGF-IFCTDQGIWSQLDHYCKEVNCSFPLFMNGISKE 2371
Query: 565 VHVITDIQVGSRINYSCTTGHRLIGHSSAEC 595
+ + G + C G+ L G ++C
Sbjct: 2372 LEMKKVYHYGDYVTLKCEDGYTLEGSPWSQC 2402
Score = 166 bits (419), Expect = 3e-40
Identities = 99/343 (28%), Positives = 157/343 (45%), Gaps = 7/343 (2%)
Query: 1643 LPHCSRVCQPPPEILHGEHT-LSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSP 1701
LP C P + T L+ + F G + Y C P Y R S+ C W+
Sbjct: 36 LPVAWGQCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYSGR-PFSIICLKNSVWTG 94
Query: 1702 EAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKAL 1761
RC KSC + + +G V + +Q G+++ + C +G+RL G S++ C+++G +
Sbjct: 95 AKDRCRRKSCRNPPDPV-NGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVI 153
Query: 1762 WNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSI 1821
W++ P+C++I C PP I NG T + YG ++Y C+ F L+GE SI
Sbjct: 154 WDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSI 213
Query: 1822 RCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGY 1881
CTS+ G+WS PAP+C +P C PP ++NG + + SL+ + + C PG+
Sbjct: 214 YCTSNDDQVGIWSGPAPQC--IIPNKCT-PPNVENGILVSDNRSLFSLNEVVEFRCQPGF 270
Query: 1882 LLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDG 1941
++ G + C W C V C P + + K + G V CE G
Sbjct: 271 VMKGPRRVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG 329
Query: 1942 YTLEGSPWSQCQADDRWDPPLAKCTSRTHDALIVGTLSGTIFF 1984
Y L G+ +C W P C ++ D + L+G + F
Sbjct: 330 YDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLF 372
>gi|148922949 complement component (3b/4b) receptor 1-like [Homo
sapiens]
Length = 569
Score = 778 bits (2009), Expect = 0.0
Identities = 391/539 (72%), Positives = 417/539 (77%), Gaps = 27/539 (5%)
Query: 25 GSLLAVVVLLALPVAWGQCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYSGRPFSI 84
G LLA +VLL + QCN PEWLPFARPTNLTD+FEFPIGTYLNYECRPGYSGRPFSI
Sbjct: 18 GLLLAALVLLLSSFS-DQCNVPEWLPFARPTNLTDDFEFPIGTYLNYECRPGYSGRPFSI 76
Query: 85 ICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSAT 144
ICLKNSVWT AKD+C+RKSCRNPPDPVNGM HVIK IQF SQIKYSC KGYRLIGSSSAT
Sbjct: 77 ICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSAT 136
Query: 145 CIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKV 204
CIISG+TVIWDN+TP+CDRI CGLPPTI NGDF S +RE FHYGSVVTY CN GS G+KV
Sbjct: 137 CIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKV 196
Query: 205 FELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEF 264
FELVGEPSIYCTS DDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEF
Sbjct: 197 FELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEF 256
Query: 265 RCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFY 324
RCQPGF MKGP VKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFY
Sbjct: 257 RCQPGFGMKGPSHVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFY 316
Query: 325 SCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDF 384
SCEPGYDLRG+ + CTPQGDWSPAAP CEVKSCDDF+GQL NG VLFP+NLQLGAKVDF
Sbjct: 317 SCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDF 376
Query: 385 VCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGR-HTGKPLEVFPFG 443
VCDEGFQLKGSSASYCVLAGMESLWNSSVPVCE+ C +PPV NG H + V G
Sbjct: 377 VCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHV---G 433
Query: 444 KTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGV-WSSPAPRCGILGHCQAPDHFLFA 502
+NY+C T LIG S+ C GN WS P C + C P L
Sbjct: 434 SRINYSCT------TGHRLIGHSSAECIL--SGNTAHWSMKPPICQQI-FCPNPPAILNG 484
Query: 503 KLKTQTNASDFPIGTSLKYECRPE-YYGRPFSITCLD----------NLVWSSPKDVCK 550
+ T T D P G + Y C P G F++ N VWSSP C+
Sbjct: 485 R-HTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVWSSPAPRCE 542
Score = 689 bits (1778), Expect = 0.0
Identities = 349/521 (66%), Positives = 377/521 (72%), Gaps = 26/521 (4%)
Query: 493 CQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRK 552
C P+ FA+ T+ +FPIGT L YECRP Y GRPFSI CL N VW+S KD CKRK
Sbjct: 35 CNVPEWLPFARPTNLTDDFEFPIGTYLNYECRPGYSGRPFSIICLKNSVWTSAKDKCKRK 94
Query: 553 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQ 612
SC+ PPDPVNGM HVI DIQ S+I YSC G+RLIG SSA CI+SGN W K P+C
Sbjct: 95 SCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCD 154
Query: 613 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 672
RI CGLPPTIANGDF S +RE FHYGSVVTY CN GS G+KVFELVGEPSIYCTS DDQV
Sbjct: 155 RIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQV 214
Query: 673 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 732
GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGF MKGP VKCQA
Sbjct: 215 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQA 274
Query: 733 LNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTP 792
LNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG+ + CTP
Sbjct: 275 LNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTP 334
Query: 793 QGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVL 852
QGDWSPAAP CEVKSCDDF+GQL NG VLFP+NLQLGAKVDFVCDEGFQLKGSSASYCVL
Sbjct: 335 QGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVL 394
Query: 853 AGMESLWNSSVPVCEQIFCPSPPVIPNGR-HTGKPLEVFPFGKAVNYTCDPHPDRGTSFD 911
AGMESLWNSSVPVCE+ C +PPV NG H + V G +NY+C T
Sbjct: 395 AGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIHV---GSRINYSCT------TGHR 445
Query: 912 LIGESTIRCTSDPQGNGV-WSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLK 970
LIG S+ C GN WS P C + C P L + T T D P G +
Sbjct: 446 LIGHSSAECIL--SGNTAHWSMKPPICQQI-FCPNPPAILNGR-HTGTPLGDIPYGKEVS 501
Query: 971 YECRPE-YYGRPFSITCLD----------NLVWSSPKDVCK 1000
Y C P G F++ N VWSSP C+
Sbjct: 502 YTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVWSSPAPRCE 542
Score = 667 bits (1722), Expect = 0.0
Identities = 338/524 (64%), Positives = 368/524 (70%), Gaps = 31/524 (5%)
Query: 943 CQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRK 1002
C P+ FA+ T+ +FPIGT L YECRP Y GRPFSI CL N VW+S KD CKRK
Sbjct: 35 CNVPEWLPFARPTNLTDDFEFPIGTYLNYECRPGYSGRPFSIICLKNSVWTSAKDKCKRK 94
Query: 1003 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQ 1062
SC+ PPDPVNGM HVI DIQ S+I YSC G+RLIG SSA CI+SGNT W K P+C
Sbjct: 95 SCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCD 154
Query: 1063 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQV 1122
RI CGLPPTIANGDF S +RE FHYGSVVTY CNLGSRG+KVFELVGEPSIYCTS DDQV
Sbjct: 155 RIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQV 214
Query: 1123 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 1182
GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGF MKGP VKCQA
Sbjct: 215 GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQA 274
Query: 1183 LNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTP 1242
LNKWEPELPSCSRVCQPPP++LH E T +DNFSPGQEVFYSCEPGYDLRG+ LHCTP
Sbjct: 275 LNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTP 334
Query: 1243 QGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVL 1302
QGDWSP APRC VKSCDDFLGQLP+G VLFPLNLQLGAKV FVCDEGF+LKGSS S+CVL
Sbjct: 335 QGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVL 394
Query: 1303 VGMRSLWNNSVPVCEHIFCPNPPAILNGR-HTGTPSGDIPYGKEISYTCDPHPDRGMTFN 1361
GM SLWN+SVPVCE C PP +NG H T DI G I+Y+C
Sbjct: 395 AGMESLWNSSVPVCERKSCETPPVPVNGMVHVIT---DIHVGSRINYSCT------TGHR 445
Query: 1362 LIGESTIRCTSDPHGNGV-WSSPAPRCELSVRAGHCKTPEQFPFASPT-IPINDFEFPVG 1419
LIG S+ C GN WS P C+ C P T P+ D P G
Sbjct: 446 LIGHSSAECILS--GNTAHWSMKPPICQQI----FCPNPPAILNGRHTGTPLGD--IPYG 497
Query: 1420 TSLNYECRP----GYFGKMFSISCLE-------NLVWSSVEDNC 1452
++Y C P G + S + N VWSS C
Sbjct: 498 KEVSYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVWSSPAPRC 541
Score = 612 bits (1577), Expect = e-174
Identities = 302/529 (57%), Positives = 358/529 (67%), Gaps = 26/529 (4%)
Query: 1389 LSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSV 1448
LS + C PE PFA PT +DFEFP+GT LNYECRPGY G+ FSI CL+N VW+S
Sbjct: 28 LSSFSDQCNVPEWLPFARPTNLTDDFEFPIGTYLNYECRPGYSGRPFSIICLKNSVWTSA 87
Query: 1449 EDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWD 1508
+D C+RKSC PP+P NGM H+ D QF S + YSC +G+RLIGS S TC++SGN V WD
Sbjct: 88 KDKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWD 147
Query: 1509 KKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYC 1568
K P+C+ I C PPTI+NGDF S +R FH G+VVTY C+ G G+++FELVGE SIYC
Sbjct: 148 NKTPVCDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYC 207
Query: 1569 TSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGS 1628
TSKDDQVG+WS P P+CI NKCT P VEN I V NRS F+L E++ FRCQPGF M G
Sbjct: 208 TSKDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGP 267
Query: 1629 HTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGA 1688
V+CQ +W P+LP CSRVCQPPP++LH E T +DNFSPGQEVFYSCEP YDLRG+
Sbjct: 268 SHVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGS 327
Query: 1689 ASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGR 1748
LHCTPQGDWSP APRC VKSCDDFLGQLP+G VL PLNLQLGAKV FVCDEGF+LKG
Sbjct: 328 TYLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGS 387
Query: 1749 SASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGR-HTGTPFGDIPYGKEISYACDTHP 1807
SAS+CVLAGM++LWNSSVPVCE+ C PP +NG H T DI G I+Y+C T
Sbjct: 388 SASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVIT---DIHVGSRINYSCTT-- 442
Query: 1808 DRGMTFNLIGESSIRCTSDPQGNGV-WSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSL 1866
LIG SS C GN WS P C+ CP+PP I NG + G +
Sbjct: 443 ----GHRLIGHSSAECIL--SGNTAHWSMKPPICQ---QIFCPNPPAILNGRHTGTPLGD 493
Query: 1867 YLPGMTISYICDP------GYLLVGKGFIFCTDQ----GIWSQLDHYCK 1905
G +SY CDP + L+G+ I T + G+WS C+
Sbjct: 494 IPYGKEVSYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVWSSPAPRCE 542
Score = 288 bits (736), Expect = 5e-77
Identities = 197/556 (35%), Positives = 268/556 (48%), Gaps = 82/556 (14%)
Query: 164 IPCGLP---PTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDD 220
+P LP PT DF F G+ + Y C PG GR SI C N
Sbjct: 37 VPEWLPFARPTNLTDDF------EFPIGTYLNYECRPGYSGRPF-------SIICLKNS- 82
Query: 221 QVGIWSGPAPQCIIPNKCTPPNVENGI--LVSDNRSLFSLNEVVEFRCQPGFVMKGPRRV 278
+W+ +C + PP+ NG+ ++ D +++ C G+ + G
Sbjct: 83 ---VWTSAKDKCKRKSCRNPPDPVNGMAHVIKD----IQFRSQIKYSCPKGYRLIGSSSA 135
Query: 279 KCQALNK---WEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG----- 329
C W+ + P C R+ C PP + + + T ++ F G V Y C G
Sbjct: 136 TCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKK 195
Query: 330 -YDLRGAASMRCTPQGD----WSPAAPTCEVKS-CDDFMGQ----LLNGRVLFPVNLQLG 379
++L G S+ CT + D WS AP C + + C + + + R LF +N
Sbjct: 196 VFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLN---- 251
Query: 380 AKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEV 439
V+F C GF +KG S C W +P C ++ C PP + + T + +
Sbjct: 252 EVVEFRCQPGFGMKGPSHVKCQALNK---WEPELPSCSRV-CQPPPDVLHAERTQRDKDN 307
Query: 440 FPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGI------LGHC 493
F G+ V Y+C+P +DL G + + CT PQG+ WS APRC + LG
Sbjct: 308 FSPGQEVFYSCEP------GYDLRGSTYLHCT--PQGD--WSPAAPRCEVKSCDDFLG-- 355
Query: 494 QAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY--GRPFSITCLDNL--VWSSPKDVC 549
Q P+ + L Q +G + + C + G S L + +W+S VC
Sbjct: 356 QLPNGHVLFPLNLQ-------LGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVC 408
Query: 550 KRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPP 609
+RKSC+TPP PVNGMVHVITDI VGSRINYSCTTGHRLIGHSSAECILSGN AHWS KPP
Sbjct: 409 ERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSMKPP 468
Query: 610 ICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSND 669
ICQ+I C PP I NG T + YG V+Y C+P F L+GE +I TS
Sbjct: 469 ICQQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRTSEP 528
Query: 670 DQVGIWSGPAPQCIIP 685
G+WS PAP+C +P
Sbjct: 529 HGNGVWSSPAPRCELP 544
Score = 200 bits (508), Expect = 1e-50
Identities = 149/537 (27%), Positives = 238/537 (44%), Gaps = 42/537 (7%)
Query: 290 LPSCSRVCQPPPDVLHAERTQRDKD-NFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSP 348
L S S C P + A T D F G + Y C PGY R S+ C W+
Sbjct: 28 LSSFSDQCNVPEWLPFARPTNLTDDFEFPIGTYLNYECRPGYSGR-PFSIICLKNSVWTS 86
Query: 349 AAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESL 408
A C+ KSC + +NG ++Q +++ + C +G++L GSS++ C+++G +
Sbjct: 87 AKDKCKRKSCRN-PPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVI 145
Query: 409 WNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTI 468
W++ PVC++I C PP I NG T E F +G V Y C+ F+L+GE +I
Sbjct: 146 WDNKTPVCDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSI 205
Query: 469 RCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY 528
CTS G+WS PAP+C I C P+ + + N S F + +++ C+P +
Sbjct: 206 YCTSKDDQVGIWSGPAPQCIIPNKCTPPN--VENGILVSDNRSLFSLNEVVEFRCQPGFG 263
Query: 529 GR-PFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNG--MVHVITDIQVGSRINYSCTTGH 585
+ P + C W C R C+ PPD ++ + G + YSC G+
Sbjct: 264 MKGPSHVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY 322
Query: 586 RLIGHSSAECILSGNAAHWSTKPPICQRIPCG-LPPTIANGDFISTNRENFHYGSVVTYR 644
L G + C G+ WS P C+ C + NG + N G+ V +
Sbjct: 323 DLRGSTYLHCTPQGD---WSPAAPRCEVKSCDDFLGQLPNGHVLFPL--NLQLGAKVDFV 377
Query: 645 CNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGIL--VSDN 702
C+ G F+L G + YC + +W+ P C + TPP NG++ ++D
Sbjct: 378 CDEG------FQLKGSSASYCVLAGME-SLWNSSVPVCERKSCETPPVPVNGMVHVITD- 429
Query: 703 RSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK---WEPELPSCSRV-CQPPPDVLHAER 758
+ + + C G + G +C W + P C ++ C PP +L+
Sbjct: 430 ---IHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSMKPPICQQIFCPNPPAILNGRH 486
Query: 759 TQRDKDNFSPGQEVFYSCEPG------YDLRGAASMRCTPQ----GDWSPAAPTCEV 805
T + G+EV Y+C+P ++L G +++R T + G WS AP CE+
Sbjct: 487 TGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVWSSPAPRCEL 543
Score = 160 bits (404), Expect = 2e-38
Identities = 93/324 (28%), Positives = 147/324 (45%), Gaps = 6/324 (1%)
Query: 1663 LSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGR 1722
L+ F G + Y C P Y R S+ C W+ +C KSC + + +G
Sbjct: 49 LTDDFEFPIGTYLNYECRPGYSGR-PFSIICLKNSVWTSAKDKCKRKSCRNPPDPV-NGM 106
Query: 1723 VLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILN 1782
+ ++Q +++ + C +G+RL G S++ C+++G +W++ PVC++I C PP I N
Sbjct: 107 AHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIAN 166
Query: 1783 GRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCEL 1842
G T YG ++Y C+ F L+GE SI CTS G+WS PAP+C
Sbjct: 167 GDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQC-- 224
Query: 1843 SVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDH 1902
+P C PP ++NG + + SL+ + + C PG+ + G + C W
Sbjct: 225 IIPNKCT-PPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELP 283
Query: 1903 YCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPL 1962
C V C P + + K + G V CE GY L GS + C W P
Sbjct: 284 SCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAA 342
Query: 1963 AKCTSRTHDALIVGTLSGTIFFIL 1986
+C ++ D + +G + F L
Sbjct: 343 PRCEVKSCDDFLGQLPNGHVLFPL 366
Score = 154 bits (390), Expect = 6e-37
Identities = 76/175 (43%), Positives = 100/175 (57%), Gaps = 4/175 (2%)
Query: 65 IGTYLNYECRPGY----SGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKG 120
+G +++ C G+ S + ++ S+W + C RKSC PP PVNGMVHVI
Sbjct: 370 LGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITD 429
Query: 121 IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFIST 180
I GS+I YSCT G+RLIG SSA CI+SG+T W + PIC +I C PP I NG T
Sbjct: 430 IHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSMKPPICQQIFCPNPPAILNGRHTGT 489
Query: 181 NRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIP 235
+ YG V+Y C+P F L+GE +I TS G+WS PAP+C +P
Sbjct: 490 PLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRTSEPHGNGVWSSPAPRCELP 544
Score = 137 bits (344), Expect = 1e-31
Identities = 123/457 (26%), Positives = 196/457 (42%), Gaps = 75/457 (16%)
Query: 1523 PTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPP 1582
PT DF F GT + Y+C G G SI C VW+S
Sbjct: 46 PTNLTDDF------EFPIGTYLNYECRPGYSGRPF-------SIICLKNS----VWTSAK 88
Query: 1583 PRCISTNKCTAPEVENAIRVPGNRSFFTLTEI-----IRFRCQPGFVMVGSHTVQCQTNG 1637
+C + P+ P N + +I I++ C G+ ++GS + C +G
Sbjct: 89 DKCKRKSCRNPPD-------PVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISG 141
Query: 1638 R---WGPKLPHCSRV-CQPPPEILHGEHTLSHQDNFSPGQEVFYSC------EPSYDLRG 1687
W K P C R+ C PP I +G+ T ++ F G V Y C + ++L G
Sbjct: 142 NTVIWDNKTPVCDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVG 201
Query: 1688 AASLHCTPQGD----WSPEAPRCTVKS-CDDFLGQLPHGRVLLPLN---LQLGAKVSFVC 1739
S++CT + D WS AP+C + + C + +G +L+ N L V F C
Sbjct: 202 EPSIYCTSKDDQVGIWSGPAPQCIIPNKCTP--PNVENG-ILVSDNRSLFSLNEVVEFRC 258
Query: 1740 DEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEI 1799
GF +KG S C W +P C ++ C PP +L+ T + G+E+
Sbjct: 259 QPGFGMKGPSHVKCQALNK---WEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEV 314
Query: 1800 SYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHY 1859
Y+C+ ++L G + + CT PQG+ WS APRCE V + ++ NGH
Sbjct: 315 FYSCEPG------YDLRGSTYLHCT--PQGD--WSPAAPRCE--VKSCDDFLGQLPNGHV 362
Query: 1860 IGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQG---IWSQLDHYCKEVNCSFP-LFM 1915
+ ++L L G + ++CD G+ L G +C G +W+ C+ +C P + +
Sbjct: 363 LFP-LNLQL-GAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCETPPVPV 420
Query: 1916 NGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQC 1952
NG+ + + H G + C G+ L G ++C
Sbjct: 421 NGM---VHVITDIHVGSRINYSCTTGHRLIGHSSAEC 454
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 685 bits (1768), Expect = 0.0
Identities = 545/2001 (27%), Positives = 803/2001 (40%), Gaps = 334/2001 (16%)
Query: 124 GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRE 183
GS++ C G++L+G+ C+ G W P C+RI CG+PP + NG + +
Sbjct: 1651 GSKVNLFCDPGFQLVGNPVQYCLNQGQ---WTQPLPHCERISCGVPPPLENGFH---SAD 1704
Query: 184 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCT---- 239
+F+ GS VTY+CN G + L+G+ ++CT N G W+G +P C+ ++C
Sbjct: 1705 DFYAGSTVTYQCNNG------YYLLGDSRMFCTDN----GSWNGVSPSCLDVDECAVGSD 1754
Query: 240 -------------------------------------PPNVENGILVSDNRSLFSLNEVV 262
P N ENG + ++++ V
Sbjct: 1755 CSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENG---HSSGEIYTVGAEV 1811
Query: 263 EFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEV 322
F CQ G+ + G ++ C +W +P C V P + E ++ F+ G +V
Sbjct: 1812 TFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAI--PENGCIEELAFTFGSKV 1869
Query: 323 FYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKV 382
Y C GY L G C WS + P CE C + NG+ + L +
Sbjct: 1870 TYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSS-PENINNGKYILS-GLTYLSTA 1927
Query: 383 DFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPF 442
+ CD G+ L+G S C +G +W+ + P C +FC PP I + TG F F
Sbjct: 1928 SYSCDTGYSLQGPSIIECTASG---IWDRAPPACHLVFCGEPPAIKDAVITGNN---FTF 1981
Query: 443 GKTVNYTCDP-------------------------------------HPDRGTSFDLIGE 465
TV YTC H T+ L G+
Sbjct: 1982 RNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDEPPIVDHASPETAHRLFGD 2041
Query: 466 STIRCTSDP-----------QGNGVWSSPA----PRCGILGHCQAPDHFLFAKLKTQTNA 510
SD G W P PRC I C+ P ++ L++ + A
Sbjct: 2042 IAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRC-IAHFCEKPPSVSYSILESVSKA 2100
Query: 511 SDFPIGTSLKYECRPEYY-GRPFSITCLDNLVWS-SPKDV-CKRKSCKTPPDPVNGMVHV 567
F G+ + ++C + I C+ W+ SP + C C PP +NG
Sbjct: 2101 K-FAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASG 2159
Query: 568 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDF 627
++ G+ + YSC G + G + C +G WS+ P C + CG PP + NG
Sbjct: 2160 -SNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQ---WSSPIPTCHPVSCGEPPKVENGFL 2215
Query: 628 ISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 687
T F S V Y+CNPG ++ VG P C +N W +P +P
Sbjct: 2216 EHTTGRIFE--SEVRYQCNPG------YKSVGSPVFVCQANRH----WHSESPLMCVPLD 2263
Query: 688 C-TPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPEL-PSCSR 745
C PP ++NG + +N F + V+F C G+ + G CQ KW + P C
Sbjct: 2264 CGKPPPIQNGFMKGEN---FEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMP 2320
Query: 746 VCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEV 805
P P +L + K+ + V +SC+ G+ L+G + ++C P W+ + P C++
Sbjct: 2321 AKCPEPPLLENQLVL--KELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKI 2378
Query: 806 KSCDDFMGQLLNGRVLFPVN-LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVP 864
C L++ V P + L G+ V + C GF L+G+S + C G W+S +P
Sbjct: 2379 VLCTP--PPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGT---WSSPLP 2433
Query: 865 VCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDP 924
C + CP P IPNG + L YTC P F+L+G +T C
Sbjct: 2434 ECVPVECPQPEEIPNGIIDVQGLAYL---STALYTCKP------GFELVGNTTTLCGE-- 2482
Query: 925 QGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY-YGRPFS 983
NG W P C + C P L K + +D G ++ Y C + P +
Sbjct: 2483 --NGHWLGGKPTCKAI-ECLKPKEILNGKF----SYTDLHYGQTVTYSCNRGFRLEGPSA 2535
Query: 984 ITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSA 1043
+TCL+ W C C +P NG V D G+ I YSC G ++ GH+
Sbjct: 2536 LTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEG-ADYSYGAIIIYSCFPGFQVAGHAMQ 2594
Query: 1044 ECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFI------------------------- 1078
C SG WS+ P C I CGLPP I GD
Sbjct: 2595 TCEESG----WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHP 2650
Query: 1079 ------------------STNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDD 1120
+T+ NF YG++V+Y CN G +EL+G P + C +
Sbjct: 2651 PYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPG------YELLGNPVLICQED-- 2702
Query: 1121 QVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 1180
G W+G AP CI P ENG L S+ S V++ C+PG ++ G C
Sbjct: 2703 --GTWNGSAPSCISIECDLPTAPENGFLRFTETSMGS---AVQYSCKPGHILAGSDLRLC 2757
Query: 1181 QALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH 1239
KW P C + C+ P +++G S N++ ++Y C+PGY L G
Sbjct: 2758 LENRKWSGASPRCEAISCKKPNPVMNGSIKGS---NYTYLSTLYYECDPGYVLNGTERRT 2814
Query: 1240 CTPQGDWSPEAPRCAVKSCDD----FLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGS 1295
C +W + P C C GQ+ F ++ + C+EGF L+G+
Sbjct: 2815 CQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQ------KEIEYTCNEGFLLEGA 2868
Query: 1296 SVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPD 1355
C+ G W+ + P C + C PP + NG G G + KE+++ C
Sbjct: 2869 RSRVCLANGS---WSGATPDCVPVRCATPPQLANGVTEGLDYG---FMKEVTFHCHEG-- 2920
Query: 1356 RGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFE 1415
+ L G + C SD G W + P C + +C PE P N F
Sbjct: 2921 ----YILHGAPKLTCQSD----GNWDAEIPLC----KPVNCGPPEDLAHGFP----NGFS 2964
Query: 1416 FPVGTSLNYECRPGYFGKMFSIS---CLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINT 1472
F G + Y+C PGY K+ S CL N WS +C C P + G V+ T
Sbjct: 2965 FIHGGHIQYQCFPGY--KLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVIEY-GTVN-GT 3020
Query: 1473 DTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYS 1532
D G C +GF+L+G TC G W P CE SC P I N
Sbjct: 3021 DFDCGKAARIQCFKGFKLLGLSEITCEADGQ---WSSGFPHCEHTSCGSLPMIPNAFI-- 3075
Query: 1533 NNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCT 1592
+ TS V+TY C +G + + G + CT K GVWS P P C + +
Sbjct: 3076 -SETSSWKENVITYSCRSG------YVIQGSSDLICTEK----GVWSQPYPVCEPLSCGS 3124
Query: 1593 APEVENAIRVPGNRSFFTLTEIIRFRCQPGFVM-VGSHTVQCQTNGRWGPKLPHCSRVCQ 1651
P V NA+ T ++ RC G+ M + T CQ +GRW P+ CS
Sbjct: 3125 PPSVANAV---ATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKC 3181
Query: 1652 PPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSP--EAPRCTVK 1709
P PE + H L H D+FS ++V SC Y G C G W P C+
Sbjct: 3182 PLPENI--THILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCSPV 3239
Query: 1710 SCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVC 1769
SC + P ++ + + + C+ G+ L+G C W+ V +C
Sbjct: 3240 SCGK--PESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQ---ENRQWSGGVAIC 3294
Query: 1770 EQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQG 1829
++ C P LNG+ + G + Y+C+ RG ++L G S CT
Sbjct: 3295 KETRCETPLEFLNGK---ADIENRTTGPNVVYSCN----RG--YSLEGPSEAHCTE---- 3341
Query: 1830 NGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFI 1889
NG WS P P C+ P CP P I + + +S C G+LL G G I
Sbjct: 3342 NGTWSHPVPLCK---PNPCPVPFVIPENALLSEKE--FYVDQNVSIKCREGFLLQGHGII 3396
Query: 1890 FCTDQGIWSQLDHYCKEVNCSFPLFM-NGISKELEMKKVYHYGDYVTLKCEDGYTLEGSP 1948
C W+Q C++++C P + N I++ + Y YGD +T C GY LEG
Sbjct: 3397 TCNPDETWTQTSAKCEKISCGPPAHVENAIARGVH----YQYGDMITYSCYSGYMLEGFL 3452
Query: 1949 WSQCQADDRW-DPPLAKCTSR 1968
S C + W PP+ + R
Sbjct: 3453 RSVCLENGTWTSPPICRAVCR 3473
Score = 588 bits (1515), Expect = e-167
Identities = 522/1890 (27%), Positives = 744/1890 (39%), Gaps = 272/1890 (14%)
Query: 42 QCNAPEWLPFARPTNLTDEFE-FPIGTYLNYECRPGYSGRPFS-IICLKNSVWTGAKDRC 99
+C AP P N E + +G + + C+ GY + I CL++ W C
Sbjct: 1788 KCKAP-----GNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYC 1842
Query: 100 RRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETP 159
+ SC P P NG + + FGS++ Y C KGY L G ++C+ + W + P
Sbjct: 1843 KAVSCGKPAIPENGCIEEL-AFTFGSKVTYRCNKGYTLAGDKESSCLANSS---WSHSPP 1898
Query: 160 ICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSND 219
+C+ + C P I NG +I + Y S +Y C+ G + L G I CT++
Sbjct: 1899 VCEPVKCSSPENINNGKYILS---GLTYLSTASYSCDTG------YSLQGPSIIECTAS- 1948
Query: 220 DQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVK 279
GIW P C + PP +++ ++ +N F+ V + C+ G+ + G ++
Sbjct: 1949 ---GIWDRAPPACHLVFCGEPPAIKDAVITGNN---FTFRNTVTYTCKEGYTLAGLDTIE 2002
Query: 280 CQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASM 338
C A KW C V C PP V HA + G FY C GY L + +
Sbjct: 2003 CLADGKWSRSDQQCLAVSCDEPPIVDHASPETAHR---LFGDIAFYYCSDGYSLADNSQL 2059
Query: 339 RCTPQGDWSPA----APTCEVKSCDDFMGQLLNGRVLFPVN---LQLGAKVDFVCDEGFQ 391
C QG W P P C C+ ++ +L V+ G+ V F C EGF
Sbjct: 2060 LCNAQGKWVPPEGQDMPRCIAHFCE--KPPSVSYSILESVSKAKFAAGSVVSFKCMEGFV 2117
Query: 392 LKGSSASYCVLAGMESLWNSSVPV---CEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNY 448
L S+ C+ G WN S P+ C + C PP I NG +G + FG V Y
Sbjct: 2118 LNTSAKIECMRGGQ---WNPS-PMSIQCIPVRCGEPPSIMNGYASGSN---YSFGAMVAY 2170
Query: 449 TCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQT 508
+C+ F + GE C + G WSSP P C + C P L+ T
Sbjct: 2171 SCN------KGFYIKGEKKSTC----EATGQWSSPIPTCHPVS-CGEPPKVENGFLEHTT 2219
Query: 509 NASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKD-VCKRKSCKTPPDPVNGMV 565
+ ++Y+C P Y G P + C N W S +C C PP NG +
Sbjct: 2220 GRI---FESEVRYQCNPGYKSVGSPVFV-CQANRHWHSESPLMCVPLDCGKPPPIQNGFM 2275
Query: 566 HVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKP-PICQRIPCGLPPTIAN 624
+ +VGS++ + C G+ L+G SS C SG W+ K P C C PP + N
Sbjct: 2276 KG-ENFEVGSKVQFFCNEGYELVGDSSWTCQKSGK---WNKKSNPKCMPAKCPEPPLLEN 2331
Query: 625 GDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCII 684
+ +E VVT+ C G L G + C + W+ P C I
Sbjct: 2332 QLVL---KELTTEVGVVTFSCKEG------HVLQGPSVLKCLPSQQ----WNDSFPVCKI 2378
Query: 685 PNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCS 744
PP + G+ + S V++ C GF ++G CQ W LP C
Sbjct: 2379 VLCTPPPLISFGVPIPS--SALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECV 2436
Query: 745 RVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCE 804
V P P+ + D + Y+C+PG++L G + C G W PTC+
Sbjct: 2437 PVECPQPEEI--PNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCK 2494
Query: 805 VKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVP 864
C ++LNG+ + +L G V + C+ GF+L+G SA C+ G W+ P
Sbjct: 2495 AIECLK-PKEILNGKFSY-TDLHYGQTVTYSCNRGFRLEGPSALTCLETGD---WDVDAP 2549
Query: 865 VCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDP 924
C I C SP I NG G + +G + Y+C P F + G + C
Sbjct: 2550 SCNAIHCDSPQPIENGFVEGAD---YSYGAIIIYSCFP------GFQVAGHAMQTCEESG 2600
Query: 925 QGNGVWSSPAPRCGILGHCQAPDHFLF---AKLKTQ------------------------ 957
WSS P C + C P H F KLK
Sbjct: 2601 -----WSSSIPTCMPI-DCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHL 2654
Query: 958 ---------------TNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCK 1000
T++S+F GT + Y C P Y G P I C ++ W+ C
Sbjct: 2655 GAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLI-CQEDGTWNGSAPSCI 2713
Query: 1001 RKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPI 1060
C P P NG + T+ +GS + YSC GH L G C+ WS P
Sbjct: 2714 SIECDLPTAPENGFLR-FTETSMGSAVQYSCKPGHILAGSDLRLCL---ENRKWSGASPR 2769
Query: 1061 CQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDD 1120
C+ I C P + NG S N+ Y S + Y C+ G + L G C + +
Sbjct: 2770 CEAISCKKPNPVMNG---SIKGSNYTYLSTLYYECDPG------YVLNGTERRTCQDDKN 2820
Query: 1121 QVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 1180
W P CI + +PP NG + D ++ + +E+ C GF+++G R C
Sbjct: 2821 ----WDEDEPICIPVDCSSPPVSANGQVRGDE---YTFQKEIEYTCNEGFLLEGARSRVC 2873
Query: 1181 QALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH 1239
A W P C V C PP++ +G + ++ +EV + C GY L GA L
Sbjct: 2874 LANGSWSGATPDCVPVRCATPPQLANG---VTEGLDYGFMKEVTFHCHEGYILHGAPKLT 2930
Query: 1240 CTPQGDWSPEAPRCAVKSC---DDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSS 1296
C G+W E P C +C +D P+G + G + + C G++L G+S
Sbjct: 2931 CQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNG-----FSFIHGGHIQYQCFPGYKLHGNS 2985
Query: 1297 VSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDR 1356
C+ G W+ S P C C + P I G GT D GK C
Sbjct: 2986 SRRCLSNGS---WSGSSPSCLPCRC-STPVIEYGTVNGT---DFDCGKAARIQC------ 3032
Query: 1357 GMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEF 1416
F L+G S I C +D G WSS P CE + P F I++
Sbjct: 3033 FKGFKLLGLSEITCEAD----GQWSSGFPHCEHTSCGSLPMIPNAF--------ISETSS 3080
Query: 1417 PVGTSLNYECRPGYFGKMFS-ISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQ 1475
+ Y CR GY + S + C E VWS C SCG PP N + T
Sbjct: 3081 WKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANAVATGEAHT- 3139
Query: 1476 FGSTVNYSCNEGFRLIGSPST-TCLVSGNNVTWDKKAPICEIISCEPPPTIS----NGDF 1530
+ S V C EG+ + T TC G W + C C P I+ +GD
Sbjct: 3140 YESEVKLRCLEGYTMDTDTDTFTCQKDGR---WFPERISCSPKKCPLPENITHILVHGDD 3196
Query: 1531 YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSP-PPRCISTN 1589
+S NR V+ C G + G C G W P S
Sbjct: 3197 FSVNRQ-------VSVSCAEG------YTFEGVNISVCQLD----GTWEPPFSDESCSPV 3239
Query: 1590 KCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV 1649
C PE V G++ +T I ++C+PG+ + G+ CQ N +W + C
Sbjct: 3240 SCGKPESPEHGFVVGSK--YTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKET 3297
Query: 1650 -CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTV 1708
C+ P E L+G+ + +N + G V YSC Y L G + HCT G WS P C
Sbjct: 3298 RCETPLEFLNGKADI---ENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKP 3354
Query: 1709 KSCD-DFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVP 1767
C F+ +P +L + VS C EGF L+G C W +
Sbjct: 3355 NPCPVPFV--IPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITC---NPDETWTQTSA 3409
Query: 1768 VCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDP 1827
CE+I C P + N G + YG I+Y+C + + L G C
Sbjct: 3410 KCEKISCGPPAHVENAIARGVHY---QYGDMITYSCYS------GYMLEGFLRSVCLE-- 3458
Query: 1828 QGNGVWSSPAPRCELSVPAACPHPPKIQNG 1857
NG W+SP P C A C P QNG
Sbjct: 3459 --NGTWTSP-PICR----AVCRFP--CQNG 3479
Score = 571 bits (1472), Expect = e-162
Identities = 483/1759 (27%), Positives = 715/1759 (40%), Gaps = 281/1759 (15%)
Query: 314 DNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP 373
++ PG +V C+PG+ L G C QG W+ P CE SC + L
Sbjct: 1646 EDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCG--VPPPLENGFHSA 1703
Query: 374 VNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVC-------------EQIF 420
+ G+ V + C+ G+ L G S +C G WN P C E
Sbjct: 1704 DDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGS---WNGVSPSCLDVDECAVGSDCSEHAS 1760
Query: 421 CPS----------PPVIPNGRHTGKPL---------------EVFPFGKTVNYTCDPHPD 455
C + PP +G++ +P+ E++ G V ++C
Sbjct: 1761 CLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQ---- 1816
Query: 456 RGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGIL--GHCQAPDHFLFAKLKTQTNASDF 513
+ L+G + I C +G W+ P C + G P++ +L F
Sbjct: 1817 --EGYQLMGVTKITCLE----SGEWNHLIPYCKAVSCGKPAIPENGCIEELA-------F 1863
Query: 514 PIGTSLKYECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQ 572
G+ + Y C Y +CL N WS VC+ C +P + NG ++++ +
Sbjct: 1864 TFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGK-YILSGLT 1922
Query: 573 VGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNR 632
S +YSC TG+ L G S EC SG W PP C + CG PP I D + T
Sbjct: 1923 YLSTASYSCDTGYSLQGPSIIECTASG---IWDRAPPACHLVFCGEPPAIK--DAVITG- 1976
Query: 633 ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPN 692
NF + + VTY C G + L G +I C ++ G WS QC+ + PP
Sbjct: 1977 NNFTFRNTVTYTCKEG------YTLAGLDTIECLAD----GKWSRSDQQCLAVSCDEPPI 2026
Query: 693 VENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP----ELPSC-SRVC 747
V++ + +R LF ++ + C G+ + ++ C A KW P ++P C + C
Sbjct: 2027 VDHASPETAHR-LF--GDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHFC 2083
Query: 748 QPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDW--SPAAPTCEV 805
+ PP V ++ K F+ G V + C G+ L +A + C G W SP + C
Sbjct: 2084 EKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIP 2143
Query: 806 KSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPV 865
C + ++NG N GA V + C++GF +KG S C G W+S +P
Sbjct: 2144 VRCGE-PPSIMNG-YASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQ---WSSPIPT 2198
Query: 866 CEQIFCPSPPVIPNG--RHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSD 923
C + C PP + NG HT + F V Y C+P + +G C
Sbjct: 2199 CHPVSCGEPPKVENGFLEHTTGRI----FESEVRYQCNP------GYKSVGSPVFVC--- 2245
Query: 924 PQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY-YGRPF 982
Q N W S +P + C P +K +F +G+ +++ C Y
Sbjct: 2246 -QANRHWHSESPLMCVPLDCGKPPPIQNGFMK----GENFEVGSKVQFFCNEGYELVGDS 2300
Query: 983 SITCLDNLVW---SSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIG 1039
S TC + W S+PK C C PP N +V +VG + +SC GH L G
Sbjct: 2301 SWTCQKSGKWNKKSNPK--CMPAKCPEPPLLENQLVLKELTTEVGV-VTFSCKEGHVLQG 2357
Query: 1040 HSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGS 1099
S +C+ S W+ P+C+ + C PP I+ G I ++ H+GS V Y C G
Sbjct: 2358 PSVLKCLPS---QQWNDSFPVCKIVLCTPPPLISFGVPIPSSA--LHFGSTVKYSCVGG- 2411
Query: 1100 RGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKC-TPPNVENGILVSDNRSLFSL 1158
F L G + C + G WS P P+C +P +C P + NGI+ D + L L
Sbjct: 2412 -----FFLRGNSTTLCQPD----GTWSSPLPEC-VPVECPQPEEIPNGII--DVQGLAYL 2459
Query: 1159 NEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPEILHGE--HTPSHQDN 1215
+ + + C+PGF + G C W P+C + C P EIL+G+ +T H
Sbjct: 2460 STAL-YTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTDLHY-- 2516
Query: 1216 FSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLN 1275
GQ V YSC G+ L G ++L C GDW +AP C CD Q + +
Sbjct: 2517 ---GQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDS--PQPIENGFVEGAD 2571
Query: 1276 LQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHT-- 1333
GA + + C GF++ G ++ C G W++S+P C I C PP I G T
Sbjct: 2572 YSYGAIIIYSCFPGFQVAGHAMQTCEESG----WSSSIPTCMPIDCGLPPHIDFGDCTKL 2627
Query: 1334 -----------------------------------------GTPSGDIPYGKEISYTCDP 1352
T S + YG +SYTC+P
Sbjct: 2628 KDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNP 2687
Query: 1353 HPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPIN 1412
+ L+G + C D G W+ AP C +S+ PT P N
Sbjct: 2688 ------GYELLGNPVLICQED----GTWNGSAPSC-ISIECD-----------LPTAPEN 2725
Query: 1413 DF----EFPVGTSLNYECRPGYF--GKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNG 1466
F E +G+++ Y C+PG+ G + CLEN WS C SC P NG
Sbjct: 2726 GFLRFTETSMGSAVQYSCKPGHILAGSDLRL-CLENRKWSGASPRCEAISCKKPNPVMNG 2784
Query: 1467 MVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTIS 1526
+ ++ + ST+ Y C+ G+ L G+ TC N WD+ PIC + C PP +
Sbjct: 2785 SIK-GSNYTYLSTLYYECDPGYVLNGTERRTCQDDKN---WDEDEPICIPVDCSSPPVSA 2840
Query: 1527 NGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCI 1586
NG + T + Y C+ G F L G RS C + G WS P C+
Sbjct: 2841 NGQVRGDEYTFQKE---IEYTCNEG------FLLEGARSRVCLAN----GSWSGATPDCV 2887
Query: 1587 STNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHC 1646
T P++ N + + F + + F C G+++ G+ + CQ++G W ++P C
Sbjct: 2888 PVRCATPPQLANGVTEGLDYGFM---KEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLC 2944
Query: 1647 SRV-CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPR 1705
V C PP ++ HG + +F G + Y C P Y L G +S C G WS +P
Sbjct: 2945 KPVNCGPPEDLAHG---FPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPS 3001
Query: 1706 CTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSS 1765
C C + + +G V + G C +GF+L G S C G W+S
Sbjct: 3002 CLPCRCSTPV--IEYGTV-NGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQ---WSSG 3055
Query: 1766 VPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTS 1825
P CE C + P I N + T I+Y+C + + + G S + CT
Sbjct: 3056 FPHCEHTSCGSLPMIPNAFISETSSWK---ENVITYSCRS------GYVIQGSSDLICTE 3106
Query: 1826 DPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVG 1885
GVWS P P CE P +C PP + N G + + C GY +
Sbjct: 3107 ----KGVWSQPYPVCE---PLSCGSPPSVANAVATG---EAHTYESEVKLRCLEGYTMDT 3156
Query: 1886 KGFIF-CTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTL 1944
F C G W C C P I+ L + V++ C +GYT
Sbjct: 3157 DTDTFTCQKDGRWFPERISCSPKKCPLP---ENITHILVHGDDFSVNRQVSVSCAEGYTF 3213
Query: 1945 EGSPWSQCQADDRWDPPLA 1963
EG S CQ D W+PP +
Sbjct: 3214 EGVNISVCQLDGTWEPPFS 3232
Score = 457 bits (1176), Expect = e-128
Identities = 402/1505 (26%), Positives = 593/1505 (39%), Gaps = 287/1505 (19%)
Query: 62 EFPIGTYLNYECRPGYS-GRPFSIICLKNSVWTGA--KDRCRRKSCRNPPDPVNGMVHVI 118
+F G+ ++++C G+ I C++ W + +C C PP +NG
Sbjct: 2101 KFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASG- 2159
Query: 119 KGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFI 178
FG+ + YSC KG+ + G +TC +G W + P C + CG PP + NG
Sbjct: 2160 SNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQ---WSSPIPTCHPVSCGEPPKVENGFLE 2216
Query: 179 STNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKC 238
T F S V Y+CNPG ++ VG P C +N W +P +P C
Sbjct: 2217 HTTGRIFE--SEVRYQCNPG------YKSVGSPVFVCQANRH----WHSESPLMCVPLDC 2264
Query: 239 -TPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPEL-PSCSRV 296
PP ++NG + +N F + V+F C G+ + G CQ KW + P C
Sbjct: 2265 GKPPPIQNGFMKGEN---FEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPA 2321
Query: 297 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVK 356
P P +L + K+ + V +SC+ G+ L+G + ++C P W+ + P C++
Sbjct: 2322 KCPEPPLLENQLVL--KELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIV 2379
Query: 357 SCDDFMGQLLNGRVLFPVN-LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPV 415
C L++ V P + L G+ V + C GF L+G+S + C G W+S +P
Sbjct: 2380 LCTP--PPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGT---WSSPLPE 2434
Query: 416 CEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQ 475
C + CP P IPNG + L T YTC P F+L+G +T C
Sbjct: 2435 CVPVECPQPEEIPNGIIDVQGLAYL---STALYTCKP------GFELVGNTTTLCGE--- 2482
Query: 476 GNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY-YGRPFSI 534
NG W P C + C P L K + +D G ++ Y C + P ++
Sbjct: 2483 -NGHWLGGKPTCKAI-ECLKPKEILNGKF----SYTDLHYGQTVTYSCNRGFRLEGPSAL 2536
Query: 535 TCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAE 594
TCL+ W C C +P NG V D G+ I YSC G ++ GH+
Sbjct: 2537 TCLETGDWDVDAPSCNAIHCDSPQPIENGFVEG-ADYSYGAIIIYSCFPGFQVAGHAMQT 2595
Query: 595 CILSGNAAHWSTKPPICQRIPCGLPPTIANGDFI-------------------------- 628
C SG WS+ P C I CGLPP I GD
Sbjct: 2596 CEESG----WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPP 2651
Query: 629 -----------------STNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
+T+ NF YG++V+Y CNPG +EL+G P + C +
Sbjct: 2652 YHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPG------YELLGNPVLICQED--- 2702
Query: 672 VGIWSGPAP-----QCIIPN---------------------------------------- 686
G W+G AP +C +P
Sbjct: 2703 -GTWNGSAPSCISIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENR 2761
Query: 687 ------------KCTPPN-VENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 733
C PN V NG + N + S + + C PG+V+ G R CQ
Sbjct: 2762 KWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLS---TLYYECDPGYVLNGTERRTCQDD 2818
Query: 734 NKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTP 792
W+ + P C V C PP + Q D ++ +E+ Y+C G+ L GA S C
Sbjct: 2819 KNWDEDEPICIPVDCSSPPVSANG---QVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLA 2875
Query: 793 QGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVL 852
G WS A P C C QL NG V ++ +V F C EG+ L G+ C
Sbjct: 2876 NGSWSGATPDCVPVRCAT-PPQLANG-VTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQS 2933
Query: 853 AGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDL 912
G W++ +P+C+ + C P + +G G F G + Y C P + L
Sbjct: 2934 DGN---WDAEIPLCKPVNCGPPEDLAHGFPNGFS---FIHGGHIQYQCFP------GYKL 2981
Query: 913 IGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYE 972
G S+ RC S NG WS +P C + C P + T N +DF G + + +
Sbjct: 2982 HGNSSRRCLS----NGSWSGSSPSC-LPCRCSTP----VIEYGT-VNGTDFDCGKAARIQ 3031
Query: 973 CRPEYYGRPFS-ITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSC 1031
C + S ITC + WSS C+ SC + P N + T + I YSC
Sbjct: 3032 CFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPMIPNAFISE-TSSWKENVITYSC 3090
Query: 1032 TTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVV 1091
+G+ + G S C G WS P+C+ + CG PP++AN ++T + + V
Sbjct: 3091 RSGYVIQGSSDLICTEKGV---WSQPYPVCEPLSCGSPPSVANA--VATGEAHTYESEVK 3145
Query: 1092 --------------TYRCNLGSRG---------RKV---------------FELVGEPSI 1113
T+ C R +K F + + S+
Sbjct: 3146 LRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDDFSVNRQVSV 3205
Query: 1114 YCTSNDDQVGI----------WSGP-APQCIIPNKC-TPPNVENGILVSDNRSLFSLNEV 1161
C G+ W P + + P C P + E+G +V S ++
Sbjct: 3206 SCAEGYTFEGVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVG---SKYTFEST 3262
Query: 1162 VEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQ 1220
+ ++C+PG+ ++G R CQ +W + C C+ P E L+G+ + +N + G
Sbjct: 3263 IIYQCEPGYELEGNRERVCQENRQWSGGVAICKETRCETPLEFLNGK---ADIENRTTGP 3319
Query: 1221 EVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCD-DFLGQLPHGRVLFPLNLQLG 1279
V YSC GY L G + HCT G WS P C C F+ +P +L +
Sbjct: 3320 NVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPCPVPFV--IPENALLSEKEFYVD 3377
Query: 1280 AKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGD 1339
VS C EGF L+G + C W + CE I C P + N G
Sbjct: 3378 QNVSIKCREGFLLQGHGIITC---NPDETWTQTSAKCEKISCGPPAHVENAIARGV---H 3431
Query: 1340 IPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVR-----AG 1394
YG I+Y+C + L G C NG W+SP P C R G
Sbjct: 3432 YQYGDMITYSC------YSGYMLEGFLRSVCLE----NGTWTSP-PICRAVCRFPCQNGG 3480
Query: 1395 HCKTP 1399
C+ P
Sbjct: 3481 ICQRP 3485
Score = 400 bits (1027), Expect = e-111
Identities = 336/1197 (28%), Positives = 488/1197 (40%), Gaps = 183/1197 (15%)
Query: 825 NLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTG 884
+L+ G+KV+ CD GFQL G+ YC+ G W +P CE+I C PP + NG H+
Sbjct: 1647 DLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQ---WTQPLPHCERISCGVPPPLENGFHSA 1703
Query: 885 KPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQ 944
+ F G V Y C+ + L+G+S + CT NG W+ +P C + C
Sbjct: 1704 ---DDFYAGSTVTYQCN------NGYYLLGDSRMFCTD----NGSWNGVSPSCLDVDECA 1750
Query: 945 APDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSC 1004
+AS + S C P Y G K+ + C
Sbjct: 1751 VGSD-------CSEHASCLNVDGSYICSCVPPYTG--------------DGKNCAEPIKC 1789
Query: 1005 KTPPDPVNGMVHVITDIQ-VGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQR 1063
K P +P NG H +I VG+ + +SC G++L+G + C+ SG W+ P C+
Sbjct: 1790 KAPGNPENG--HSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGE---WNHLIPYCKA 1844
Query: 1064 IPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVG 1123
+ CG P NG F +GS VTYRCN G + L G+ C +N
Sbjct: 1845 VSCGKPAIPENG---CIEELAFTFGSKVTYRCNKG------YTLAGDKESSCLANSS--- 1892
Query: 1124 IWSGPAPQCIIPNKCTPP-NVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 1182
WS P C P KC+ P N+ NG + + S + C G+ ++GP ++C A
Sbjct: 1893 -WSHSPPVCE-PVKCSSPENINNGKYILSGLTYLS---TASYSCDTGYSLQGPSIIECTA 1947
Query: 1183 LNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCT 1241
W+ P+C V C PP I T + NF+ V Y+C+ GY L G ++ C
Sbjct: 1948 SGIWDRAPPACHLVFCGEPPAIKDAVITGN---NFTFRNTVTYTCKEGYTLAGLDTIECL 2004
Query: 1242 PQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCV 1301
G WS +C SCD+ + H L G + C +G+ L +S C
Sbjct: 2005 ADGKWSRSDQQCLAVSCDE-PPIVDHASPETAHRL-FGDIAFYYCSDGYSLADNSQLLCN 2062
Query: 1302 LVGMRSLW----NNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRG 1357
G W +P C FC PP++ G +S+ C G
Sbjct: 2063 AQGK---WVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCM----EG 2115
Query: 1358 MTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFP 1417
N + I C G W+ P+P +S++ + E + +++ F
Sbjct: 2116 FVLNT--SAKIECMR----GGQWN-PSP---MSIQCIPVRCGEPPSIMNGYASGSNYSF- 2164
Query: 1418 VGTSLNYECRPGYFGKMFSIS-CLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQF 1476
G + Y C G++ K S C WSS C SCG PP+ NG + T F
Sbjct: 2165 -GAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIF 2223
Query: 1477 GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPI-CEIISCEPPPTISNGDFYSNNR 1535
S V Y CN G++ +GSP C N W ++P+ C + C PP I NG N
Sbjct: 2224 ESEVRYQCNPGYKSVGSPVFVCQA---NRHWHSESPLMCVPLDCGKPPPIQNGFMKGEN- 2279
Query: 1536 TSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPP-PRCISTNKCTAP 1594
F G+ V + C+ G +ELVG+ S C + G W+ P+C+ P
Sbjct: 2280 --FEVGSKVQFFCNEG------YELVGDSSWTC----QKSGKWNKKSNPKCMPAKCPEPP 2327
Query: 1595 EVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPP 1653
+EN + + + T ++ F C+ G V+ G ++C + +W P C V C PP
Sbjct: 2328 LLENQLVL---KELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPP 2384
Query: 1654 PEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDD 1713
P I G S +F G V YSC + LRG ++ C P G WS P C C
Sbjct: 2385 PLISFGVPIPSSALHF--GSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQ 2442
Query: 1714 FLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIF 1773
++P+G ++ L + + C GF L G + + C G W P C+ I
Sbjct: 2443 -PEEIPNG-IIDVQGLAYLSTALYTCKPGFELVGNTTTLC---GENGHWLGGKPTCKAIE 2497
Query: 1774 CPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVW 1833
C P ILNG+ + T D+ YG+ ++Y+C +RG F L G S++ C G W
Sbjct: 2498 CLKPKEILNGKFSYT---DLHYGQTVTYSC----NRG--FRLEGPSALTCLE----TGDW 2544
Query: 1834 SSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTD 1893
AP C C P I+NG G Y G I Y C PG+ + G C +
Sbjct: 2545 DVDAPSCN---AIHCDSPQPIENGFVEGAD---YSYGAIIIYSCFPGFQVAGHAMQTCEE 2598
Query: 1894 QGIWSQLDHYCKEVNCSFPLFMN------------GISKELEMKKV--------YH---- 1929
G WS C ++C P ++ +E +M +V YH
Sbjct: 2599 SG-WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAV 2657
Query: 1930 -------------------YGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKCTS 1967
YG V+ C GY L G+P CQ D W+ C S
Sbjct: 2658 AKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCIS 2714
Score = 256 bits (653), Expect = 2e-67
Identities = 216/811 (26%), Positives = 325/811 (40%), Gaps = 127/811 (15%)
Query: 1208 HTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPH 1267
H + ++ PG +V C+PG+ L G +C QG W+ P C SC G P
Sbjct: 1640 HLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISC----GVPPP 1695
Query: 1268 GRVLFPL--NLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVC--------- 1316
F + G+ V++ C+ G+ L G S C G WN P C
Sbjct: 1696 LENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGS---WNGVSPSCLDVDECAVG 1752
Query: 1317 ----EHIFCPN----------PPAILNGRHTGTP--------------SGDI-PYGKEIS 1347
EH C N PP +G++ P SG+I G E++
Sbjct: 1753 SDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVT 1812
Query: 1348 YTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASP 1407
++C + L+G + I C +G W+ P C+ +V G PE
Sbjct: 1813 FSCQE------GYQLMGVTKITCLE----SGEWNHLIPYCK-AVSCGKPAIPENG----- 1856
Query: 1408 TIPINDFEFPVGTSLNYECRPGY-FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNG 1466
I + F G+ + Y C GY SCL N WS C C PE N
Sbjct: 1857 --CIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCS-SPENINN 1913
Query: 1467 MVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTIS 1526
+I + + ST +YSC+ G+ L G C SG WD+ P C ++ C PP I
Sbjct: 1914 GKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASG---IWDRAPPACHLVFCGEPPAIK 1970
Query: 1527 NGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCI 1586
+ NN T F N VTY C G + L G +I C + G WS +C+
Sbjct: 1971 DAVITGNNFT-FRN--TVTYTCKEG------YTLAGLDTIECLAD----GKWSRSDQQCL 2017
Query: 1587 STNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRW----GPK 1642
+ + P V++A +R F +I + C G+ + + + C G+W G
Sbjct: 2018 AVSCDEPPIVDHASPETAHRLF---GDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQD 2074
Query: 1643 LPHC-SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDW-- 1699
+P C + C+ PP + + + F+ G V + C + L +A + C G W
Sbjct: 2075 MPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNP 2134
Query: 1700 SPEAPRCTVKSCDDFLGQLPH--GRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAG 1757
SP + +C C G+ P N GA V++ C++GF +KG S C G
Sbjct: 2135 SPMSIQCIPVRC----GEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATG 2190
Query: 1758 MKALWNSSVPVCEQIFCPNPPAILNG--RHTGTPFGDIPYGKEISYACDTHPDRGMTFNL 1815
W+S +P C + C PP + NG HT G I + E+ Y C+ +
Sbjct: 2191 Q---WSSPIPTCHPVSCGEPPKVENGFLEHT---TGRI-FESEVRYQCNP------GYKS 2237
Query: 1816 IGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISY 1875
+G C Q N W S +P + VP C PP IQNG G + + G + +
Sbjct: 2238 VGSPVFVC----QANRHWHSESPL--MCVPLDCGKPPPIQNGFMKGENFEV---GSKVQF 2288
Query: 1876 ICDPGYLLVGKGFIFCTDQGIWSQLDH-YCKEVNCSFPLFMNGISKELEMKKVYHYGDYV 1934
C+ GY LVG C G W++ + C C P + +L +K++ V
Sbjct: 2289 FCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPL---LENQLVLKELTTEVGVV 2345
Query: 1935 TLKCEDGYTLEGSPWSQCQADDRWDPPLAKC 1965
T C++G+ L+G +C +W+ C
Sbjct: 2346 TFSCKEGHVLQGPSVLKCLPSQQWNDSFPVC 2376
Score = 159 bits (401), Expect = 3e-38
Identities = 118/393 (30%), Positives = 164/393 (41%), Gaps = 68/393 (17%)
Query: 1619 CQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPPPEILHGEHTLSHQDNFSPGQEVFY 1677
C PGF +VG+ C G+W LPHC R+ C PP + +G H+ D+F G V Y
Sbjct: 1658 CDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHSA---DDFYAGSTVTY 1714
Query: 1678 SCEPSYDLRGAASLHCTPQGDWSPEAPRCT-VKSCDDFLGQLPHGRVL------------ 1724
C Y L G + + CT G W+ +P C V C H L
Sbjct: 1715 QCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVP 1774
Query: 1725 ----------------LPLNLQ----------LGAKVSFVCDEGFRLKGRSASHCVLAGM 1758
P N + +GA+V+F C EG++L G + C+ +G
Sbjct: 1775 PYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGE 1834
Query: 1759 KALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGE 1818
WN +P C+ + C P NG F +G +++Y C+ +G T L G+
Sbjct: 1835 ---WNHLIPYCKAVSCGKPAIPENGCIEELAF---TFGSKVTYRCN----KGYT--LAGD 1882
Query: 1819 SSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICD 1878
C + N WS P CE P C P I NG YI ++ YL T SY CD
Sbjct: 1883 KESSCLA----NSSWSHSPPVCE---PVKCSSPENINNGKYILSGLT-YLS--TASYSCD 1932
Query: 1879 PGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKC 1938
GY L G I CT GIW + C V C P I + + + + VT C
Sbjct: 1933 TGYSLQGPSIIECTASGIWDRAPPACHLVFCGEP---PAIKDAVITGNNFTFRNTVTYTC 1989
Query: 1939 EDGYTLEGSPWSQCQADDRWDPPLAKCTSRTHD 1971
++GYTL G +C AD +W +C + + D
Sbjct: 1990 KEGYTLAGLDTIECLADGKWSRSDQQCLAVSCD 2022
Score = 134 bits (337), Expect = 9e-31
Identities = 119/447 (26%), Positives = 180/447 (40%), Gaps = 64/447 (14%)
Query: 69 LNYECRPGYSGRPFS-IICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQI 127
+ Y CR GY + S +IC + VW+ C SC +PP N V + + S++
Sbjct: 3086 ITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANA-VATGEAHTYESEV 3144
Query: 128 KYSCTKGYRL-IGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITN----GDFISTNR 182
K C +GY + + + TC G W E C C LP IT+ GD S NR
Sbjct: 3145 KLRCLEGYTMDTDTDTFTCQKDGR---WFPERISCSPKKCPLPENITHILVHGDDFSVNR 3201
Query: 183 ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGP-APQCIIPNKC-TP 240
+ V+ C G + G C + G W P + + P C P
Sbjct: 3202 Q-------VSVSCAEG------YTFEGVNISVCQLD----GTWEPPFSDESCSPVSCGKP 3244
Query: 241 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQP 299
+ E+G +V S ++ + ++C+PG+ ++G R CQ +W + C C+
Sbjct: 3245 ESPEHGFVVG---SKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKETRCET 3301
Query: 300 PPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCD 359
P + L+ + D +N + G V YSC GY L G + CT G WS P C+ C
Sbjct: 3302 PLEFLNGKA---DIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPCP 3358
Query: 360 -DFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQ 418
F+ + +L + V C EGF L+G C + W + CE+
Sbjct: 3359 VPFV--IPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITC---NPDETWTQTSAKCEK 3413
Query: 419 IFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNG 478
I C P + N G + +G + Y+C + + L G C NG
Sbjct: 3414 ISCGPPAHVENAIARGVH---YQYGDMITYSC------YSGYMLEGFLRSVCLE----NG 3460
Query: 479 VWSSPAPRCGIL--------GHCQAPD 497
W+SP P C + G CQ P+
Sbjct: 3461 TWTSP-PICRAVCRFPCQNGGICQRPN 3486
Score = 68.9 bits (167), Expect = 5e-11
Identities = 48/167 (28%), Positives = 68/167 (40%), Gaps = 15/167 (8%)
Query: 1618 RCQPGFVMVGSHTVQCQTNGRWGPKLPHCS-RVCQPPPEILHGEHTLSHQDNFSPGQEVF 1676
RC PGF +VGS + C NG W +C R C + HG + S ++
Sbjct: 405 RCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYK-TTCL 463
Query: 1677 YSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLN-----LQL 1731
+C+ Y L G+ L C W PRC + C F Q+P ++ P N +
Sbjct: 464 VACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTF--QMPKDVIISPHNCGKQPAKF 521
Query: 1732 GAKVSFVCDEGFRLKG-RSASHCVLAGMKALWNSSV--PVCEQIFCP 1775
G C +GF L G + C +G WN V VC+ + P
Sbjct: 522 GTICYVSCRQGFILSGVKEMLRCTTSGK---WNVGVQAAVCKDVEAP 565
Score = 68.6 bits (166), Expect = 6e-11
Identities = 63/225 (28%), Positives = 90/225 (40%), Gaps = 43/225 (19%)
Query: 131 CTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSV 190
C +GYR G + C+ + C NG FI N N H+ +
Sbjct: 362 CREGYRASGQT-------------------CELVHCPALKPPENGYFIQ-NTCNNHFNAA 401
Query: 191 VTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCII---PNKCTPPNVENGI 247
RC+PG F+LVG I C N G+WSG C + P+ P + I
Sbjct: 402 CGVRCHPG------FDLVGSSIILCLPN----GLWSGSESYCRVRTCPHLRQPKH--GHI 449
Query: 248 LVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC-SRVC---QPPPDV 303
S L+ +V C G+ ++G ++ CQ ++W+ P C R C Q P DV
Sbjct: 450 SCSTREMLYKTTCLVA--CDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDV 507
Query: 304 LHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASM-RCTPQGDWS 347
+ + K G + SC G+ L G M RCT G W+
Sbjct: 508 IISPH-NCGKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWN 551
Score = 68.2 bits (165), Expect = 8e-11
Identities = 58/195 (29%), Positives = 83/195 (42%), Gaps = 24/195 (12%)
Query: 611 CQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDD 670
C+ + C NG FI N N H+ + RC+PG F+LVG I C N
Sbjct: 373 CELVHCPALKPPENGYFIQ-NTCNNHFNAACGVRCHPG------FDLVGSSIILCLPN-- 423
Query: 671 QVGIWSGPAPQCII---PNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRR 727
G+WSG C + P+ P + I S L+ +V C G+ ++G +
Sbjct: 424 --GLWSGSESYCRVRTCPHLRQPKH--GHISCSTREMLYKTTCLVA--CDEGYRLEGSDK 477
Query: 728 VKCQALNKWEPELPSC-SRVC---QPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLR 783
+ CQ ++W+ P C R C Q P DV+ + K G + SC G+ L
Sbjct: 478 LTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPH-NCGKQPAKFGTICYVSCRQGFILS 536
Query: 784 GAASM-RCTPQGDWS 797
G M RCT G W+
Sbjct: 537 GVKEMLRCTTSGKWN 551
Score = 64.3 bits (155), Expect = 1e-09
Identities = 110/437 (25%), Positives = 161/437 (36%), Gaps = 81/437 (18%)
Query: 1189 ELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSP 1248
EL C + +PP ++T ++ N + G C PG+DL G++ + C P G WS
Sbjct: 374 ELVHCPAL-KPPENGYFIQNTCNNHFNAACGVR----CHPGFDLVGSSIILCLPNGLWSG 428
Query: 1249 EAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFV-CDEGFRLKGSSVSHCVLVGMRS 1307
C V++C L Q HG + L V CDEG+RL+GS C S
Sbjct: 429 SESYCRVRTC-PHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTC---QGNS 484
Query: 1308 LWNNSVPVCEHIFCPN---PPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIG 1364
W+ P C C P ++ H G P + C +G + +
Sbjct: 485 QWDGPEPRCVERHCSTFQMPKDVIISPHN---CGKQP--AKFGTICYVSCRQGFILSGVK 539
Query: 1365 ESTIRCTSDPHGN-GVWS-------SPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEF 1416
E +RCT+ N GV + +P C + A KT EQ A+ T I +
Sbjct: 540 E-MLRCTTSGKWNVGVQAAVCKDVEAPQINCPKDIEA---KTLEQQDSANVTWQIPTAKD 595
Query: 1417 PVGTSLNYECRPGYFGK-MFSISCLENLVWSSVEDNCRRKSC------------------ 1457
G ++ P + +F I + +V+++ + + + SC
Sbjct: 596 NSGEKVSVHVHPAFTPPYLFPIGDVA-IVYTATDLSGNQASCIFHIKVIDAEPPVIDWCR 654
Query: 1458 GPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPS----------------TTCLVS 1501
PPP + VH + +S N G L+ + S T S
Sbjct: 655 SPPPVQVSEKVHAAS----WDEPQFSDNSGAELVITRSHTQGDLFPQGETIVQYTATDPS 710
Query: 1502 GNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELV 1561
GNN T D + + CE P T NGDF T + G T C G D F
Sbjct: 711 GNNRTCDIHI-VIKGSPCEIPFTPVNGDFIC---TPDNTGVNCTLTCLEGYD----FTEG 762
Query: 1562 GERSIYCTSKDDQVGVW 1578
YC +D GVW
Sbjct: 763 STDKYYCAYED---GVW 776
Score = 63.5 bits (153), Expect = 2e-09
Identities = 54/195 (27%), Positives = 74/195 (37%), Gaps = 31/195 (15%)
Query: 1795 YGKEISYACDTHPDRGMTFNLIGE-----SSIRC-----TSDPQGNGV--------WSSP 1836
YGK + Y C P T+ G S I C TS P + +
Sbjct: 312 YGKGLQYECTACPSG--TYKPEGSPGGISSCIPCPDENHTSPPGSTSPEDCVCREGYRAS 369
Query: 1837 APRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGI 1896
CEL CP +NG++I + + C PG+ LVG I C G+
Sbjct: 370 GQTCEL---VHCPALKPPENGYFIQNTCNNHF-NAACGVRCHPGFDLVGSSIILCLPNGL 425
Query: 1897 WSQLDHYCKEVNCSF---PLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQ 1953
WS + YC+ C P + EM Y + C++GY LEGS CQ
Sbjct: 426 WSGSESYCRVRTCPHLRQPKHGHISCSTREML----YKTTCLVACDEGYRLEGSDKLTCQ 481
Query: 1954 ADDRWDPPLAKCTSR 1968
+ +WD P +C R
Sbjct: 482 GNSQWDGPEPRCVER 496
Score = 63.2 bits (152), Expect = 3e-09
Identities = 55/195 (28%), Positives = 81/195 (41%), Gaps = 24/195 (12%)
Query: 1061 CQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDD 1120
C+ + C NG FI N N H+ + RC+ G F+LVG I C N
Sbjct: 373 CELVHCPALKPPENGYFIQ-NTCNNHFNAACGVRCHPG------FDLVGSSIILCLPN-- 423
Query: 1121 QVGIWSGPAPQCII---PNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRR 1177
G+WSG C + P+ P + I S L+ +V C G+ ++G +
Sbjct: 424 --GLWSGSESYCRVRTCPHLRQPKH--GHISCSTREMLYKTTCLVA--CDEGYRLEGSDK 477
Query: 1178 VKCQALNKWEPELPSC-SRVC---QPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLR 1233
+ CQ ++W+ P C R C Q P +++ H Q G + SC G+ L
Sbjct: 478 LTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQP-AKFGTICYVSCRQGFILS 536
Query: 1234 GAAS-LHCTPQGDWS 1247
G L CT G W+
Sbjct: 537 GVKEMLRCTTSGKWN 551
Score = 58.5 bits (140), Expect = 6e-08
Identities = 72/289 (24%), Positives = 98/289 (33%), Gaps = 52/289 (17%)
Query: 1679 CEPSYDLRGAASLHCT--PQGDWSPEAPRCTVKSC---DDFLGQLPHGRVLLPLNLQLGA 1733
CE Y +G CT P G + PE + SC D P G +
Sbjct: 307 CEKGYYGKGL-QYECTACPSGTYKPEGSPGGISSCIPCPDENHTSPPGST---------S 356
Query: 1734 KVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDI 1793
VC EG+R G++ CE + CP NG F
Sbjct: 357 PEDCVCREGYRASGQT-------------------CELVHCPALKPPENGY-----FIQN 392
Query: 1794 PYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPK 1853
+ AC G F+L+G S I C NG+WS C + CPH +
Sbjct: 393 TCNNHFNAACGVRCHPG--FDLVGSSIILCLP----NGLWSGSESYCRVRT---CPHLRQ 443
Query: 1854 IQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPL 1913
++GH I L T CD GY L G + C W + C E +CS
Sbjct: 444 PKHGH-ISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQ 502
Query: 1914 FMNG--ISKELEMKKVYHYGDYVTLKCEDGYTLEG-SPWSQCQADDRWD 1959
IS K+ +G + C G+ L G +C +W+
Sbjct: 503 MPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWN 551
Score = 58.5 bits (140), Expect = 6e-08
Identities = 55/226 (24%), Positives = 85/226 (37%), Gaps = 24/226 (10%)
Query: 1452 CRRKSCGPPPEPFNGMVHINT-DTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKK 1510
C C P NG NT + F + C+ GF L+GS CL +G W
Sbjct: 373 CELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNG---LWSGS 429
Query: 1511 APICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTS 1570
C + +C +G + R + T + C G + L G + C
Sbjct: 430 ESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLV-ACDEG------YRLEGSDKLTCQG 482
Query: 1571 KDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGN--RSFFTLTEIIRFRCQPGFVMVG- 1627
W P PRC+ + T ++ I P N + I C+ GF++ G
Sbjct: 483 NSQ----WDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGV 538
Query: 1628 SHTVQCQTNGRW--GPKLPHCSRVCQPP---PEILHGEHTLSHQDN 1668
++C T+G+W G + C V P P+ + + TL QD+
Sbjct: 539 KEMLRCTTSGKWNVGVQAAVCKDVEAPQINCPKDIEAK-TLEQQDS 583
Score = 55.5 bits (132), Expect = 5e-07
Identities = 39/134 (29%), Positives = 59/134 (44%), Gaps = 10/134 (7%)
Query: 1642 KLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSP 1701
+L HC + +PP ++T ++ N + G C P +DL G++ + C P G WS
Sbjct: 374 ELVHCPAL-KPPENGYFIQNTCNNHFNAACGVR----CHPGFDLVGSSIILCLPNGLWSG 428
Query: 1702 EAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFV-CDEGFRLKGRSASHCVLAGMKA 1760
C V++C L Q HG + L V CDEG+RL+G C +
Sbjct: 429 SESYCRVRTC-PHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTC---QGNS 484
Query: 1761 LWNSSVPVCEQIFC 1774
W+ P C + C
Sbjct: 485 QWDGPEPRCVERHC 498
Score = 54.3 bits (129), Expect = 1e-06
Identities = 53/195 (27%), Positives = 83/195 (42%), Gaps = 23/195 (11%)
Query: 289 ELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSP 348
EL C + +PP + + T + N + G C PG+DL G++ + C P G WS
Sbjct: 374 ELVHCPAL-KPPENGYFIQNTCNNHFNAACGVR----CHPGFDLVGSSIILCLPNGLWSG 428
Query: 349 AAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFV-CDEGFQLKGSSASYCVLAGMES 407
+ C V++C + Q +G + L V CDEG++L+GS C S
Sbjct: 429 SESYCRVRTC-PHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTC---QGNS 484
Query: 408 LWNSSVPVCEQIFCPS----PPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLI 463
W+ P C + C + VI + + GK + FG +C F L
Sbjct: 485 QWDGPEPRCVERHCSTFQMPKDVIISPHNCGK--QPAKFGTICYVSC------RQGFILS 536
Query: 464 G-ESTIRCTSDPQGN 477
G + +RCT+ + N
Sbjct: 537 GVKEMLRCTTSGKWN 551
Score = 54.3 bits (129), Expect = 1e-06
Identities = 53/195 (27%), Positives = 83/195 (42%), Gaps = 23/195 (11%)
Query: 739 ELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSP 798
EL C + +PP + + T + N + G C PG+DL G++ + C P G WS
Sbjct: 374 ELVHCPAL-KPPENGYFIQNTCNNHFNAACGVR----CHPGFDLVGSSIILCLPNGLWSG 428
Query: 799 AAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFV-CDEGFQLKGSSASYCVLAGMES 857
+ C V++C + Q +G + L V CDEG++L+GS C S
Sbjct: 429 SESYCRVRTC-PHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTC---QGNS 484
Query: 858 LWNSSVPVCEQIFCPS----PPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLI 913
W+ P C + C + VI + + GK + FG +C F L
Sbjct: 485 QWDGPEPRCVERHCSTFQMPKDVIISPHNCGK--QPAKFGTICYVSC------RQGFILS 536
Query: 914 G-ESTIRCTSDPQGN 927
G + +RCT+ + N
Sbjct: 537 GVKEMLRCTTSGKWN 551
Score = 52.8 bits (125), Expect = 3e-06
Identities = 44/177 (24%), Positives = 75/177 (42%), Gaps = 13/177 (7%)
Query: 73 CRPGYSGRPFSII-CLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHV-IKGIQFGSQIKYS 130
C PG+ SII CL N +W+G++ CR ++C + P +G + + + + + +
Sbjct: 406 CHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVA 465
Query: 131 CTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCG---LPPTITNGDFISTNRENFHY 187
C +GYRL GS TC G++ WD P C C +P + + ++ +
Sbjct: 466 CDEGYRLEGSDKLTC--QGNSQ-WDGPEPRCVERHCSTFQMPKDVIISPH-NCGKQPAKF 521
Query: 188 GSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVE 244
G++ C G + V E TS VG+ + P P ++E
Sbjct: 522 GTICYVSCRQGF----ILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAPQINCPKDIE 574
Score = 46.2 bits (108), Expect = 3e-04
Identities = 60/231 (25%), Positives = 78/231 (33%), Gaps = 42/231 (18%)
Query: 266 CQPGFVMKGPRRVKCQAL--NKWEPE-LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEV 322
C+ G+ KG + +C A ++PE P C P PD H + SP V
Sbjct: 307 CEKGYYGKG-LQYECTACPSGTYKPEGSPGGISSCIPCPDENHTS----PPGSTSPEDCV 361
Query: 323 FYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKV 382
C GY G TCE+ C + N A
Sbjct: 362 ---CREGYRASGQ----------------TCELVHCPALKPPENGYFIQNTCNNHFNAAC 402
Query: 383 DFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPF 442
C GF L GSS C+ G LW+ S C CP +G + E+ +
Sbjct: 403 GVRCHPGFDLVGSSIILCLPNG---LWSGSESYCRVRTCPHLRQPKHGHISCSTREML-Y 458
Query: 443 GKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHC 493
T CD + L G + C QGN W P PRC + HC
Sbjct: 459 KTTCLVACDE------GYRLEGSDKLTC----QGNSQWDGPEPRC-VERHC 498
Score = 45.4 bits (106), Expect = 6e-04
Identities = 61/231 (26%), Positives = 78/231 (33%), Gaps = 42/231 (18%)
Query: 716 CQPGFVMKGPRRVKCQAL--NKWEPE-LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEV 772
C+ G+ KG + +C A ++PE P C P PD H + SP V
Sbjct: 307 CEKGYYGKG-LQYECTACPSGTYKPEGSPGGISSCIPCPDENHTS----PPGSTSPEDCV 361
Query: 773 FYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKV 832
C GY G TCE+ C + N A
Sbjct: 362 ---CREGYRASGQ----------------TCELVHCPALKPPENGYFIQNTCNNHFNAAC 402
Query: 833 DFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPF 892
C GF L GSS C+ G LW+ S C CP +G + E+
Sbjct: 403 GVRCHPGFDLVGSSIILCLPNG---LWSGSESYCRVRTCPHLRQPKHGHISCSTREML-- 457
Query: 893 GKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHC 943
TC D G + L G + C QGN W P PRC + HC
Sbjct: 458 ---YKTTCLVACDEG--YRLEGSDKLTC----QGNSQWDGPEPRC-VERHC 498
Score = 43.1 bits (100), Expect = 0.003
Identities = 55/236 (23%), Positives = 77/236 (32%), Gaps = 47/236 (19%)
Query: 776 CEPGYDLRGAASMRCT--PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVD 833
CE GY +G CT P G + P + SC + P + + D
Sbjct: 307 CEKGYYGKGL-QYECTACPSGTYKPEGSPGGISSCIPCPDE---NHTSPPGST---SPED 359
Query: 834 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFG 893
VC EG++ G + CE + CP+ NG F
Sbjct: 360 CVCREGYRASGQT-------------------CELVHCPALKPPENGYFIQNTCNNH-FN 399
Query: 894 KAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGI--LGHCQAPDHFLF 951
A C P FDL+G S I C NG+WS C + H + P H
Sbjct: 400 AACGVRCHP------GFDLVGSSIILCLP----NGLWSGSESYCRVRTCPHLRQPKHGHI 449
Query: 952 AKLKTQTNASDFPIGTSLKYECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCKT 1006
+ + + T+ C Y +TC N W P+ C + C T
Sbjct: 450 S-----CSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCST 500
Score = 37.0 bits (84), Expect = 0.20
Identities = 36/165 (21%), Positives = 62/165 (37%), Gaps = 12/165 (7%)
Query: 534 ITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVIT-DIQVGSRINYSCTTGHRLIGHSS 592
I CL N +WS + C+ ++C P +G + T ++ + +C G+RL G
Sbjct: 418 ILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDK 477
Query: 593 AECILSGNAAHWSTKPPICQRIPCG---LPPTIANGDFISTNRENFHYGSVVTYRCNPGS 649
C GN + W P C C +P + + ++ +G++ C G
Sbjct: 478 LTC--QGN-SQWDGPEPRCVERHCSTFQMPKDVIISPH-NCGKQPAKFGTICYVSCRQGF 533
Query: 650 GGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVE 694
+ V E TS VG+ + P P ++E
Sbjct: 534 ----ILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAPQINCPKDIE 574
Score = 36.6 bits (83), Expect = 0.26
Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 4/84 (4%)
Query: 984 ITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVIT-DIQVGSRINYSCTTGHRLIGHSS 1042
I CL N +WS + C+ ++C P +G + T ++ + +C G+RL G
Sbjct: 418 ILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDK 477
Query: 1043 AECILSGNTAHWSTKPPICQRIPC 1066
C GN + W P C C
Sbjct: 478 LTC--QGN-SQWDGPEPRCVERHC 498
>gi|42544177 complement component (3d/Epstein Barr virus) receptor 2
isoform 2 [Homo sapiens]
Length = 1033
Score = 603 bits (1555), Expect = e-172
Identities = 372/1048 (35%), Positives = 501/1048 (47%), Gaps = 126/1048 (12%)
Query: 1064 IPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVG 1123
I CG PP I NG IS G+V+ Y C+ F L+GE S+ C + D G
Sbjct: 21 ISCGSPPPILNGR-ISYYSTPIAVGTVIRYSCS------GTFRLIGEKSLLCITKDKVDG 73
Query: 1124 IWSGPAPQCIIPNK---CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 1180
W PAP+C NK C P V G + + + + V F C+ F M G + V C
Sbjct: 74 TWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTP-YRHGDSVTFACKTNFSMNGNKSVWC 132
Query: 1181 QALNKWEP-ELPSCSRV----CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGA 1235
QA N W P LP+C V C P I +G HT + + +PG V YSCE GY L G
Sbjct: 133 QANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGE 192
Query: 1236 ASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGS 1295
++C G WS P C C LG+ P+G+V P L++G +F CDEG+RL+G
Sbjct: 193 KIINCLSSGKWSAVPPTCEEARCKS-LGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGP 251
Query: 1296 SVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPD 1355
S CV+ G W +PVCE IFCP+PP ILNGRH G ++ YG ++YTCDP P+
Sbjct: 252 PSSRCVIAGQGVAWTK-MPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPE 310
Query: 1356 RGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPE--------------- 1400
G+ F LIGEST+RCT D G WS PAPRCELS A C P+
Sbjct: 311 EGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYT 370
Query: 1401 ---------QFPFA---------------SPTIPINDFE-------------------FP 1417
F F P+ P+ + E F
Sbjct: 371 YNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFD 430
Query: 1418 VGTSLNYECRPGYF--GKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQ 1475
GTS+ Y C PGY G+ SI C VW+ C+ +C E + Q
Sbjct: 431 PGTSIKYSCNPGYVLVGEE-SIQCTSEGVWTPPVPQCKVAAC----EATGRQLLTKPQHQ 485
Query: 1476 F-GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNN 1534
F VN SC EG++L GS C + W + +C+ I+C PPP I NG ++
Sbjct: 486 FVRPDVNSSCGEGYKLSGSVYQECQ---GTIPWFMEIRLCKEITCPPPPVIYNGAHTGSS 542
Query: 1535 RTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRC---ISTNKC 1591
F GT VTY C+ GP+ F L+GE +I CTS D + G WS P P C + +C
Sbjct: 543 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 602
Query: 1592 TAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSR-VC 1650
+ + N ++ G + + + + F+C GF + GS ++C+ + W P++P C + C
Sbjct: 603 SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETC 662
Query: 1651 QPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHC--TPQGDWSPEAPRCTV 1708
Q H +L S + V SC+ Y L G A C G W + P C V
Sbjct: 663 Q------HVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKV 716
Query: 1709 KSCDDFLGQLPHGRV--LLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGM-KALWNSS 1765
C + +G+ ++ N G +VS+ CD+GF L G C W+
Sbjct: 717 IHCHP-PPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGP 775
Query: 1766 VPVCEQ----IFCPNPPAI----LNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIG 1817
P C + CPNP LN H+ DI Y D +P F + G
Sbjct: 776 SPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVY-------VDCNPG----FIMNG 824
Query: 1818 ESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYIC 1877
IRC +D W P C CP PPK NG++ GG+++ + PGM+I Y C
Sbjct: 825 SRVIRCHTD----NTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSC 880
Query: 1878 DPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLK 1937
D GYLLVG+ + CT +G WSQ +CKEVNCS P M+GI K LE +K+Y YG VTL+
Sbjct: 881 DQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLE 940
Query: 1938 CEDGYTLEGSPWSQCQADDRWDPPLAKCTSRTHDALIVGTLSGTIFFILLIIFLSWIILK 1997
CEDGY LEGSP SQCQ+D +W+PPLA C SR+ ++ G +G I LI+ ++I K
Sbjct: 941 CEDGYMLEGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCGIAAGLILLTFLIVITLYVISK 1000
Query: 1998 HRKGNNAHENPKEVAIHLHSQGGSSVHP 2025
HR N + ++ A HL ++ SV P
Sbjct: 1001 HRARNYYTDTSQKEAFHLEAREVYSVDP 1028
Score = 560 bits (1444), Expect = e-159
Identities = 329/981 (33%), Positives = 483/981 (49%), Gaps = 70/981 (7%)
Query: 365 LLNGRV-LFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAG-MESLWNSSVPVCEQI--- 419
+LNGR+ + + +G + + C F+L G + C+ ++ W+ P CE
Sbjct: 29 ILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPKCEYFNKY 88
Query: 420 -FCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNG 478
CP P ++P G + + + G +V + C T+F + G ++ C Q N
Sbjct: 89 SSCPEP-IVPGG-YKIRGSTPYRHGDSVTFACK------TNFSMNGNKSVWC----QANN 136
Query: 479 VWS-SPAPRCGILGHCQAPD-HFLFAKLKTQTNASDFPIGTSLKYECRPEYY--GRPFSI 534
+W + P C + + P + T N G S+ Y C Y G I
Sbjct: 137 MWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKI-I 195
Query: 535 TCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAE 594
CL + WS+ C+ CK+ NG V ++VG N+ C G+RL G S+
Sbjct: 196 NCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSR 255
Query: 595 CILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKV 654
C+++G W TK P+C+ I C PP I NG I + N YGS+VTY C+P
Sbjct: 256 CVIAGQGVAW-TKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVN 314
Query: 655 FELVGEPSIYCTSNDDQVGIWSGPAPQCIIPN---KCTPPNVENGILVSDNRSLFSLNEV 711
F L+GE ++ CT + + G WSGPAP+C + +C P + G +VS + ++ N+
Sbjct: 315 FILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDT 374
Query: 712 VEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQE 771
V F C GF +KG ++++C A WEP P C + CQ PP++L+ ++ R F PG
Sbjct: 375 VIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFDPGTS 434
Query: 772 VFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAK 831
+ YSC PGY L G S++CT +G W+P P C+V +C+ QLL P + +
Sbjct: 435 IKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTK----PQHQFVRPD 490
Query: 832 VDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFP 891
V+ C EG++L GS C W + +C++I CP PPVI NG HTG LE FP
Sbjct: 491 VNSSCGEGYKLSGSVYQECQGT---IPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFP 547
Query: 892 FGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLF 951
+G V YTC+P P+RG F LIGESTIRCTS+ Q G WS PAP C + H
Sbjct: 548 YGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHI 607
Query: 952 AK-LKTQTNASDFPIGTSLKYECRPEYYGRPFS-ITCLDNLVWSSPKDVCKRKSCKTPPD 1009
A K + + ++ ++C + + S I C + W VC++++C+
Sbjct: 608 ANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQ---- 663
Query: 1010 PVNGMVHV---ITDIQVGSR---INYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQR 1063
HV + ++ GSR +N SC G++L GH+ C W K P+C+
Sbjct: 664 ------HVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMC-QDAENGIWFKKIPLCKV 716
Query: 1064 IPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVG 1123
I C PP I NG ENF YG+ V+Y C+ G F L+GE + C S+ G
Sbjct: 717 IHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQG------FYLLGEKKLQCRSDSKGHG 770
Query: 1124 IWSGPAPQCIIP---NKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 1180
WSGP+PQC+ +C P V++G ++ S +S N++V C PGF+M G R ++C
Sbjct: 771 SWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRC 830
Query: 1181 QALNKWEPELPSCSRV----CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAA 1236
N W P +P+C + C PPP+ +G HT + FSPG + YSC+ GY L G A
Sbjct: 831 HTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEA 890
Query: 1237 SLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNL-QLGAKVSFVCDEGFRLKGS 1295
L CT +G WS AP C +C + L P + Q GA V+ C++G+ L+GS
Sbjct: 891 LLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGS 950
Query: 1296 SVSHCVLVGMRSLWNNSVPVC 1316
S C WN + VC
Sbjct: 951 PQSQC---QSDHQWNPPLAVC 968
Score = 523 bits (1348), Expect = e-148
Identities = 292/825 (35%), Positives = 421/825 (51%), Gaps = 56/825 (6%)
Query: 66 GTYLNYECRPGYSGRPFSII-CLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFG 124
G + Y C GY II CL + W+ C C++ NG V ++ G
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVG 235
Query: 125 SQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNREN 184
+ C +GYRL G S+ C+I+G V W + P+C+ I C PP I NG I + N
Sbjct: 236 VTANFFCDEGYRLQGPPSSRCVIAGQGVAW-TKMPVCEEIFCPSPPPILNGRHIGNSLAN 294
Query: 185 FHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPN---KCTPP 241
YGS+VTY C+P F L+GE ++ CT + + G WSGPAP+C + +C P
Sbjct: 295 VSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHP 354
Query: 242 NVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPP 301
+ G +VS + ++ N+ V F C GF +KG ++++C A WEP P C + CQ PP
Sbjct: 355 QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPP 414
Query: 302 DVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF 361
++L+ ++ R F PG + YSC PGY L G S++CT +G W+P P C+V +C+
Sbjct: 415 NILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEAT 474
Query: 362 MGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFC 421
QLL P + + V+ C EG++L GS C W + +C++I C
Sbjct: 475 GRQLLTK----PQHQFVRPDVNSSCGEGYKLSGSVYQEC---QGTIPWFMEIRLCKEITC 527
Query: 422 PSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 481
P PPVI NG HTG LE FP+G TV YTC+P P+RG F LIGESTIRCTS+ Q G WS
Sbjct: 528 PPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWS 587
Query: 482 SPAPRCGILGHCQAPDHFLFAK-LKTQTNASDFPIGTSLKYECRPEYYGRPFS-ITCLDN 539
PAP C + H A K + + ++ ++C + + S I C +
Sbjct: 588 GPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKAD 647
Query: 540 LVWSSPKDVCKRKSCKTPPDPVNGMVHV---ITDIQVGSR---INYSCTTGHRLIGHSSA 593
W VC++++C+ HV + ++ GSR +N SC G++L GH+
Sbjct: 648 NTWDPEIPVCEKETCQ----------HVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQ 697
Query: 594 ECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRK 653
C + N W K P+C+ I C PP I NG ENF YG+ V+Y C+ G
Sbjct: 698 MCQDAENGI-WFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQG----- 751
Query: 654 VFELVGEPSIYCTSNDDQVGIWSGPAPQCIIP---NKCTPPNVENGILVSDNRSLFSLNE 710
F L+GE + C S+ G WSGP+PQC+ +C P V++G ++ S +S N+
Sbjct: 752 -FYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHND 810
Query: 711 VVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV----CQPPPDVLHAERTQRDKDNF 766
+V C PGF+M G R ++C N W P +P+C + C PPP + T + F
Sbjct: 811 IVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARF 870
Query: 767 SPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCD-----DFMGQLLNGRVL 821
SPG + YSC+ GY L G A + CT +G WS AP C+ +C D + + L R +
Sbjct: 871 SPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKM 930
Query: 822 FPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVC 866
+ Q GA V C++G+ L+GS S C + WN + VC
Sbjct: 931 Y----QYGAVVTLECEDGYMLEGSPQSQC---QSDHQWNPPLAVC 968
Score = 448 bits (1152), Expect = e-125
Identities = 309/986 (31%), Positives = 434/986 (44%), Gaps = 124/986 (12%)
Query: 164 IPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVG 223
I CG PP I NG IS G+V+ Y C+ F L+GE S+ C + D G
Sbjct: 21 ISCGSPPPILNGR-ISYYSTPIAVGTVIRYSCSG------TFRLIGEKSLLCITKDKVDG 73
Query: 224 IWSGPAPQCIIPNK---CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 280
W PAP+C NK C P V G + + + + V F C+ F M G + V C
Sbjct: 74 TWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTP-YRHGDSVTFACKTNFSMNGNKSVWC 132
Query: 281 QALNKWEP-ELPSCSRV----CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 335
QA N W P LP+C V C P + + T + + +PG V YSCE GY L G
Sbjct: 133 QANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGE 192
Query: 336 ASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGS 395
+ C G WS PTCE C +G+ NG+V P L++G +F CDEG++L+G
Sbjct: 193 KIINCLSSGKWSAVPPTCEEARCKS-LGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGP 251
Query: 396 SASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPD 455
+S CV+AG W + +PVCE+IFCPSPP I NGRH G L +G V YTCDP P+
Sbjct: 252 PSSRCVIAGQGVAW-TKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPE 310
Query: 456 RGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGI-LGHCQAPDHFLFAKLKTQTNASDFP 514
G +F LIGEST+RCT D Q G WS PAPRC + Q P + +
Sbjct: 311 EGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYT 370
Query: 515 IGTSLKYECRPEYYGR-PFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMV---HVITD 570
++ + C + + I C W VC+ K C+ PP+ +NG H++
Sbjct: 371 YNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCE-KECQAPPNILNGQKEDRHMVR- 428
Query: 571 IQVGSRINYSCTTGHRLIGHSSAECILSG----------------NAAHWSTKPP----- 609
G+ I YSC G+ L+G S +C G TKP
Sbjct: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVR 488
Query: 610 --------------------------------ICQRIPCGLPPTIANGDFISTNRENFHY 637
+C+ I C PP I NG ++ E+F Y
Sbjct: 489 PDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPY 548
Query: 638 GSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC---IIPNKCTPPNVE 694
G+ VTY CNPG F L+GE +I CTSND + G WSGPAP C ++ +C+ ++
Sbjct: 549 GTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIA 608
Query: 695 NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSR-VCQPPPDV 753
NG +S + + N+ V F+C GF +KG +++C+A N W+PE+P C + CQ
Sbjct: 609 NGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQ----- 663
Query: 754 LHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRC--TPQGDWSPAAPTCEVKSCDDF 811
H ++ ++ S + V SC+ GY L G A C G W P C+V C
Sbjct: 664 -HVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHP- 721
Query: 812 MGQLLNGR--VLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGM-ESLWNSSVPVCEQ 868
++NG+ + N G +V + CD+GF L G C W+ P C +
Sbjct: 722 PPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLR 781
Query: 869 ----IFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDP 924
CP+P V +G K + V C+P F + G IRC +D
Sbjct: 782 SPPVTRCPNPEV-KHGYKLNKTHSAYSHNDIVYVDCNP------GFIMNGSRVIRCHTD- 833
Query: 925 QGNGVWSSPAPRC---GILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YG 979
W P C +G C P T N + F G S+ Y C Y G
Sbjct: 834 ---NTWVPGVPTCIKKAFIG-CPPPPKTPNGN-HTGGNIARFSPGMSILYSCDQGYLLVG 888
Query: 980 RPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITD---IQVGSRINYSCTTGHR 1036
+ C WS P CK +C +P D ++G+ + Q G+ + C G+
Sbjct: 889 EAL-LLCTHEGTWSQPAPHCKEVNCSSPAD-MDGIQKGLEPRKMYQYGAVVTLECEDGYM 946
Query: 1037 LIGHSSAECILSGNTAHWSTKPPICQ 1062
L G ++C + W+ +C+
Sbjct: 947 LEGSPQSQC---QSDHQWNPPLAVCR 969
Score = 229 bits (584), Expect = 2e-59
Identities = 176/589 (29%), Positives = 252/589 (42%), Gaps = 67/589 (11%)
Query: 37 PVAWGQCNAPEWLPFARPTNLTDEFE------FPIGTYLNYECRPGY--SGRPFSIICLK 88
PV +C AP P L + E F GT + Y C PGY G SI C
Sbjct: 404 PVCEKECQAP-------PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEE-SIQCTS 455
Query: 89 NSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQF-GSQIKYSCTKGYRLIGSSSATCII 147
VWT +C+ +C + + QF + SC +GY+L GS C
Sbjct: 456 EGVWTPPVPQCKVAAC----EATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQEC-- 509
Query: 148 SGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFEL 207
T+ W E +C I C PP I NG ++ E+F YG+ VTY CNPG F L
Sbjct: 510 -QGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSL 568
Query: 208 VGEPSIYCTSNDDQVGIWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEF 264
+GE +I CTSND + G WSGPAP C ++ +C+ ++ NG +S + + N+ V F
Sbjct: 569 IGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTF 628
Query: 265 RCQPGFVMKGPRRVKCQALNKWEPELPSCSR-VCQPPPDVLHAERTQRDKDNFSPGQEVF 323
+C GF +KG +++C+A N W+PE+P C + CQ H ++ ++ S + V
Sbjct: 629 KCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQ------HVRQSLQELPAGSRVELVN 682
Query: 324 YSCEPGYDLRGAASMRC--TPQGDWSPAAPTCEVKSCDDFMGQLLNGR--VLFPVNLQLG 379
SC+ GY L G A C G W P C+V C ++NG+ + N G
Sbjct: 683 TSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHP-PPVIVNGKHTGMMAENFLYG 741
Query: 380 AKVDFVCDEGFQLKGSSASYCVLAGM-ESLWNSSVPVCEQ----IFCPSPPVIPNGRHTG 434
+V + CD+GF L G C W+ P C + CP+P V +G
Sbjct: 742 NEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEV-KHGYKLN 800
Query: 435 KPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC---GILG 491
K + V C+P F + G IRC +D W P C +G
Sbjct: 801 KTHSAYSHNDIVYVDCNP------GFIMNGSRVIRCHTD----NTWVPGVPTCIKKAFIG 850
Query: 492 HCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVC 549
C P T N + F G S+ Y C Y G + C WS P C
Sbjct: 851 -CPPPPKTPNGN-HTGGNIARFSPGMSILYSCDQGYLLVGEAL-LLCTHEGTWSQPAPHC 907
Query: 550 KRKSCKTPPDPVNGMVHVITD---IQVGSRINYSCTTGHRLIGHSSAEC 595
K +C +P D ++G+ + Q G+ + C G+ L G ++C
Sbjct: 908 KEVNCSSPAD-MDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQC 955
Score = 198 bits (503), Expect = 5e-50
Identities = 199/811 (24%), Positives = 302/811 (37%), Gaps = 112/811 (13%)
Query: 65 IGTYLNYECRPGY--SGRPFS--IICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHV--- 117
+G N+ C GY G P S +I + WT C C +PP +NG H+
Sbjct: 234 VGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWT-KMPVCEEIFCPSPPPILNGR-HIGNS 291
Query: 118 IKGIQFGSQIKYSCTK------GYRLIGSSSATCII-SGDTVIWDNETPICDRIPCGLP- 169
+ + +GS + Y+C + LIG S+ C + S T W P C+ +
Sbjct: 292 LANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQC 351
Query: 170 --PTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSG 227
P I G +S ++ + Y V + C G F L G I C + G W
Sbjct: 352 PHPQILRGRMVSGQKDRYTYNDTVIFACMFG------FTLKGSKQIRCNAQ----GTWEP 401
Query: 228 PAPQCIIPNKC-TPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKW 286
AP C +C PPN+ NG + F +++ C PG+V+ G ++C + W
Sbjct: 402 SAPVC--EKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVW 459
Query: 287 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQ----EVFYSCEPGYDLRGAASMRCTP 342
P +P C V E T R Q +V SC GY L G+ C
Sbjct: 460 TPPVPQCK--------VAACEATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQG 511
Query: 343 QGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPV--NLQLGAKVDFVCDEG------FQLKG 394
W C+ +C + NG + G V + C+ G F L G
Sbjct: 512 TIPWFMEIRLCKEITCPP-PPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIG 570
Query: 395 SSASYCVLAGME-SLWNSSVPVCE----QIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYT 449
S C E W+ P+C+ + C + + +GK F + TV +
Sbjct: 571 ESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYF-YNDTVTFK 629
Query: 450 CDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTN 509
C + F L G S IRC +D W P C CQ + +
Sbjct: 630 CY------SGFTLKGSSQIRCKAD----NTWDPEIPVCE-KETCQ----------HVRQS 668
Query: 510 ASDFPIGTSLKY---ECRPEYY--GRPFSITCLD--NLVWSSPKDVCKRKSCKTPPDPVN 562
+ P G+ ++ C+ Y G + + C D N +W +CK C PP VN
Sbjct: 669 LQELPAGSRVELVNTSCQDGYQLTGHAYQM-CQDAENGIWFKKIPLCKVIHCHPPPVIVN 727
Query: 563 GMVH--VITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAH--WSTKPPICQRIP--- 615
G + + G+ ++Y C G L+G +C S + H WS P C R P
Sbjct: 728 GKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQC-RSDSKGHGSWSGPSPQCLRSPPVT 786
Query: 616 -CGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGI 674
C P + +G ++ + + +V CNPG F + G I C +++
Sbjct: 787 RCP-NPEVKHGYKLNKTHSAYSHNDIVYVDCNPG------FIMNGSRVIRCHTDNT---- 835
Query: 675 WSGPAPQCI---IPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ 731
W P CI PP NG N + FS + + C G+++ G + C
Sbjct: 836 WVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCT 895
Query: 732 ALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRC 790
W P C V C P D+ ++ + + G V CE GY L G+ +C
Sbjct: 896 HEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQC 955
Query: 791 TPQGDWSPAAPTCEVKSCDDFMGQLLNGRVL 821
W+P C +S + + G +L
Sbjct: 956 QSDHQWNPPLAVCRSRSLAPVLCGIAAGLIL 986
Score = 191 bits (486), Expect = 5e-48
Identities = 132/438 (30%), Positives = 191/438 (43%), Gaps = 97/438 (22%)
Query: 62 EFPIGTYLNYECRPG-YSGRPFSII------CLKN----SVWTG---------------- 94
+FP GT + Y C PG G FS+I C N W+G
Sbjct: 545 DFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSH 604
Query: 95 -----------------------------------AKDRCRRKSCRNPPDPV---NGMVH 116
++ RC+ + +P PV H
Sbjct: 605 VHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKETCQH 664
Query: 117 VIKGIQ---FGSQIKY---SCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPP 170
V + +Q GS+++ SC GY+L G + C + IW + P+C I C PP
Sbjct: 665 VRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMC-QDAENGIWFKKIPLCKVIHCHPPP 723
Query: 171 TITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 230
I NG ENF YG+ V+Y C+ G F L+GE + C S+ G WSGP+P
Sbjct: 724 VIVNGKHTGMMAENFLYGNEVSYECDQG------FYLLGEKKLQCRSDSKGHGSWSGPSP 777
Query: 231 QCIIP---NKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWE 287
QC+ +C P V++G ++ S +S N++V C PGF+M G R ++C N W
Sbjct: 778 QCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWV 837
Query: 288 PELPSCSRV----CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ 343
P +P+C + C PPP + T + FSPG + YSC+ GY L G A + CT +
Sbjct: 838 PGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHE 897
Query: 344 GDWSPAAPTCEVKSCD-----DFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSAS 398
G WS AP C+ +C D + + L R ++ Q GA V C++G+ L+GS S
Sbjct: 898 GTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMY----QYGAVVTLECEDGYMLEGSPQS 953
Query: 399 YCVLAGMESLWNSSVPVC 416
C + WN + VC
Sbjct: 954 QC---QSDHQWNPPLAVC 968
Score = 100 bits (249), Expect = 1e-20
Identities = 79/327 (24%), Positives = 128/327 (39%), Gaps = 28/327 (8%)
Query: 62 EFPIGT---YLNYECRPGY--SGRPFSIIC-LKNSVWTGAKDRCRRKSCRNPPDPVNGMV 115
E P G+ +N C+ GY +G + + +N +W C+ C PP VNG
Sbjct: 671 ELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKH 730
Query: 116 H--VIKGIQFGSQIKYSCTKGYRLIGSSSATCII-SGDTVIWDNETPICDRIP----CGL 168
+ + +G+++ Y C +G+ L+G C S W +P C R P C
Sbjct: 731 TGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCP- 789
Query: 169 PPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGP 228
P + +G ++ + + +V CNPG F + G I C +++ W
Sbjct: 790 NPEVKHGYKLNKTHSAYSHNDIVYVDCNPG------FIMNGSRVIRCHTDNT----WVPG 839
Query: 229 APQCI---IPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK 285
P CI PP NG N + FS + + C G+++ G + C
Sbjct: 840 VPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGT 899
Query: 286 WEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQG 344
W P C V C P D+ ++ + + G V CE GY L G+ +C
Sbjct: 900 WSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDH 959
Query: 345 DWSPAAPTCEVKSCDDFMGQLLNGRVL 371
W+P C +S + + G +L
Sbjct: 960 QWNPPLAVCRSRSLAPVLCGIAAGLIL 986
>gi|54792123 complement component (3d/Epstein Barr virus) receptor 2
isoform 1 [Homo sapiens]
Length = 1092
Score = 603 bits (1555), Expect = e-172
Identities = 378/1101 (34%), Positives = 509/1101 (46%), Gaps = 173/1101 (15%)
Query: 1064 IPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVG 1123
I CG PP I NG IS G+V+ Y C+ F L+GE S+ C + D G
Sbjct: 21 ISCGSPPPILNGR-ISYYSTPIAVGTVIRYSCS------GTFRLIGEKSLLCITKDKVDG 73
Query: 1124 IWSGPAPQCIIPNK---CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 1180
W PAP+C NK C P V G + + + + V F C+ F M G + V C
Sbjct: 74 TWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTP-YRHGDSVTFACKTNFSMNGNKSVWC 132
Query: 1181 QALNKWEP-ELPSCSRV----CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGA 1235
QA N W P LP+C V C P I +G HT + + +PG V YSCE GY L G
Sbjct: 133 QANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGE 192
Query: 1236 ASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGS 1295
++C G WS P C C LG+ P+G+V P L++G +F CDEG+RL+G
Sbjct: 193 KIINCLSSGKWSAVPPTCEEARCKS-LGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGP 251
Query: 1296 SVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPD 1355
S CV+ G W +PVCE IFCP+PP ILNGRH G ++ YG ++YTCDP P+
Sbjct: 252 PSSRCVIAGQGVAWTK-MPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPE 310
Query: 1356 RGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPE--------------- 1400
G+ F LIGEST+RCT D G WS PAPRCELS A C P+
Sbjct: 311 EGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYT 370
Query: 1401 ---------QFPFA---------------SPTIPINDFE-------------------FP 1417
F F P+ P+ + E F
Sbjct: 371 YNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVRFD 430
Query: 1418 VGTSLNYECRPGYF--GKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQ 1475
GTS+ Y C PGY G+ SI C VW+ C+ +C E + Q
Sbjct: 431 PGTSIKYSCNPGYVLVGEE-SIQCTSEGVWTPPVPQCKVAAC----EATGRQLLTKPQHQ 485
Query: 1476 F-GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNN 1534
F VN SC EG++L GS C + W + +C+ I+C PPP I NG ++
Sbjct: 486 FVRPDVNSSCGEGYKLSGSVYQECQ---GTIPWFMEIRLCKEITCPPPPVIYNGAHTGSS 542
Query: 1535 RTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRC---ISTNKC 1591
F GT VTY C+ GP+ F L+GE +I CTS D + G WS P P C + +C
Sbjct: 543 LEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC 602
Query: 1592 TAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQ 1651
+ + N ++ G + + + + F+C GF + GS ++C+ + W P++P C + CQ
Sbjct: 603 SHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQ 662
Query: 1652 PPPEILHGEHTLSH------------------------------QDNFSPG--------- 1672
PP + HG HT + N+SP
Sbjct: 663 SPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCEETCQ 722
Query: 1673 ---------------QEVFYSCEPSYDLRGAASLHC--TPQGDWSPEAPRCTVKSCDDFL 1715
+ V SC+ Y L G A C G W + P C V C
Sbjct: 723 HVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHP-P 781
Query: 1716 GQLPHGRV--LLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGM-KALWNSSVPVCEQ- 1771
+ +G+ ++ N G +VS+ CD+GF L G C W+ P C +
Sbjct: 782 PVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRS 841
Query: 1772 ---IFCPNPPAI----LNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCT 1824
CPNP LN H+ DI Y D +P F + G IRC
Sbjct: 842 PPVTRCPNPEVKHGYKLNKTHSAYSHNDIVY-------VDCNPG----FIMNGSRVIRCH 890
Query: 1825 SDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLV 1884
+D W P C CP PPK NG++ GG+++ + PGM+I Y CD GYLLV
Sbjct: 891 TD----NTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLV 946
Query: 1885 GKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTL 1944
G+ + CT +G WSQ +CKEVNCS P M+GI K LE +K+Y YG VTL+CEDGY L
Sbjct: 947 GEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYML 1006
Query: 1945 EGSPWSQCQADDRWDPPLAKCTSRTHDALIVGTLSGTIFFILLIIFLSWIILKHRKGNNA 2004
EGSP SQCQ+D +W+PPLA C SR+ ++ G +G I LI+ ++I KHR N
Sbjct: 1007 EGSPQSQCQSDHQWNPPLAVCRSRSLAPVLCGIAAGLILLTFLIVITLYVISKHRARNYY 1066
Query: 2005 HENPKEVAIHLHSQGGSSVHP 2025
+ ++ A HL ++ SV P
Sbjct: 1067 TDTSQKEAFHLEAREVYSVDP 1087
Score = 556 bits (1432), Expect = e-157
Identities = 351/1051 (33%), Positives = 486/1051 (46%), Gaps = 126/1051 (11%)
Query: 164 IPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVG 223
I CG PP I NG IS G+V+ Y C+ F L+GE S+ C + D G
Sbjct: 21 ISCGSPPPILNGR-ISYYSTPIAVGTVIRYSCSG------TFRLIGEKSLLCITKDKVDG 73
Query: 224 IWSGPAPQCIIPNK---CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 280
W PAP+C NK C P V G + + + + V F C+ F M G + V C
Sbjct: 74 TWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTP-YRHGDSVTFACKTNFSMNGNKSVWC 132
Query: 281 QALNKWEP-ELPSCSRV----CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 335
QA N W P LP+C V C P + + T + + +PG V YSCE GY L G
Sbjct: 133 QANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGE 192
Query: 336 ASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGS 395
+ C G WS PTCE C +G+ NG+V P L++G +F CDEG++L+G
Sbjct: 193 KIINCLSSGKWSAVPPTCEEARCKS-LGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGP 251
Query: 396 SASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPD 455
+S CV+AG W + +PVCE+IFCPSPP I NGRH G L +G V YTCDP P+
Sbjct: 252 PSSRCVIAGQGVAW-TKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPE 310
Query: 456 RGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGI-LGHCQAPDHFLFAKLKTQTNASDFP 514
G +F LIGEST+RCT D Q G WS PAPRC + Q P + +
Sbjct: 311 EGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYT 370
Query: 515 IGTSLKYECRPEYYGR-PFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMV---HVITD 570
++ + C + + I C W VC+ K C+ PP+ +NG H++
Sbjct: 371 YNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCE-KECQAPPNILNGQKEDRHMVR- 428
Query: 571 IQVGSRINYSCTTGHRLIGHSSAECILSG----------------NAAHWSTKPP----- 609
G+ I YSC G+ L+G S +C G TKP
Sbjct: 429 FDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQFVR 488
Query: 610 --------------------------------ICQRIPCGLPPTIANGDFISTNRENFHY 637
+C+ I C PP I NG ++ E+F Y
Sbjct: 489 PDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPY 548
Query: 638 GSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC---IIPNKCTPPNVE 694
G+ VTY CNPG F L+GE +I CTSND + G WSGPAP C ++ +C+ ++
Sbjct: 549 GTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIA 608
Query: 695 NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVL 754
NG +S + + N+ V F+C GF +KG +++C+A N W+PE+P C + CQ PP +
Sbjct: 609 NGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLH 668
Query: 755 HAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQ 814
H T + F G V Y+C+PGY L G S+ C P G+WSP+AP CE ++C
Sbjct: 669 HGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCMPSGNWSPSAPRCE-ETCQHVRQS 727
Query: 815 LLNGRVLFPVNLQLGAKVDFV---CDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFC 871
L L G++V+ V C +G+QL G + C A +W +P+C+ I C
Sbjct: 728 L--------QELPAGSRVELVNTSCQDGYQLTGHAYQMCQDA-ENGIWFKKIPLCKVIHC 778
Query: 872 PSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 931
PPVI NG+HTG E F +G V+Y CD F L+GE ++C SD +G+G WS
Sbjct: 779 HPPPVIVNGKHTGMMAENFLYGNEVSYECD------QGFYLLGEKKLQCRSDSKGHGSWS 832
Query: 932 SPAPRC---GILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY-YGRPFSITCL 987
P+P+C + C P+ + K S + + +C P + I C
Sbjct: 833 GPSPQCLRSPPVTRCPNPE--VKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCH 890
Query: 988 DNLVWSSPKDVCKRKS---CKTPPDPVNGMVHV---ITDIQVGSRINYSCTTGHRLIGHS 1041
+ W C +K+ C PP NG H I G I YSC G+ L+G +
Sbjct: 891 TDNTWVPGVPTCIKKAFIGCPPPPKTPNGN-HTGGNIARFSPGMSILYSCDQGYLLVGEA 949
Query: 1042 SAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRG 1101
C G WS P C+ + C P + R+ + YG+VVT C G
Sbjct: 950 LLLCTHEGT---WSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDG--- 1003
Query: 1102 RKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 1132
+ L G P C S+ W+ P C
Sbjct: 1004 ---YMLEGSPQSQCQSDHQ----WNPPLAVC 1027
Score = 504 bits (1298), Expect = e-142
Identities = 295/878 (33%), Positives = 421/878 (47%), Gaps = 103/878 (11%)
Query: 66 GTYLNYECRPGYSGRPFSII-CLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFG 124
G + Y C GY II CL + W+ C C++ NG V ++ G
Sbjct: 176 GLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVG 235
Query: 125 SQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNREN 184
+ C +GYRL G S+ C+I+G V W + P+C+ I C PP I NG I + N
Sbjct: 236 VTANFFCDEGYRLQGPPSSRCVIAGQGVAW-TKMPVCEEIFCPSPPPILNGRHIGNSLAN 294
Query: 185 FHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPN---KCTPP 241
YGS+VTY C+P F L+GE ++ CT + + G WSGPAP+C + +C P
Sbjct: 295 VSYGSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHP 354
Query: 242 NVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPP 301
+ G +VS + ++ N+ V F C GF +KG ++++C A WEP P C + CQ PP
Sbjct: 355 QILRGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGTWEPSAPVCEKECQAPP 414
Query: 302 DVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF 361
++L+ ++ R F PG + YSC PGY L G S++CT +G W+P P C+V +C+
Sbjct: 415 NILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQCKVAACEAT 474
Query: 362 MGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFC 421
QLL P + + V+ C EG++L GS C W + +C++I C
Sbjct: 475 GRQLLTK----PQHQFVRPDVNSSCGEGYKLSGSVYQEC---QGTIPWFMEIRLCKEITC 527
Query: 422 PSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 481
P PPVI NG HTG LE FP+G TV YTC+P P+RG F LIGESTIRCTS+ Q G WS
Sbjct: 528 PPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWS 587
Query: 482 SPAPRCGILGHCQAPDHFLFAK-LKTQTNASDFPIGTSLKYECRPEYYGRPFS-ITCLDN 539
PAP C + H A K + + ++ ++C + + S I C +
Sbjct: 588 GPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKAD 647
Query: 540 LVWSSPKDVCKRKSCKTPPDPVNGMVHV---ITDIQVGSRINYSCTTGHRLIGHSSAECI 596
W VC+ K C++PP +G H G ++Y+C G+ L+G+ S C+
Sbjct: 648 NTWDPEIPVCE-KGCQSPPGLHHGR-HTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHCM 705
Query: 597 LSGNAAHWSTKPPIC-----------QRIPCGL--------------------------- 618
SGN WS P C Q +P G
Sbjct: 706 PSGN---WSPSAPRCEETCQHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAE 762
Query: 619 ------------------PPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGE 660
PP I NG ENF YG+ V+Y C+ G F L+GE
Sbjct: 763 NGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQG------FYLLGE 816
Query: 661 PSIYCTSNDDQVGIWSGPAPQCIIP---NKCTPPNVENGILVSDNRSLFSLNEVVEFRCQ 717
+ C S+ G WSGP+PQC+ +C P V++G ++ S +S N++V C
Sbjct: 817 KKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCN 876
Query: 718 PGFVMKGPRRVKCQALNKWEPELPSCSRV----CQPPPDVLHAERTQRDKDNFSPGQEVF 773
PGF+M G R ++C N W P +P+C + C PPP + T + FSPG +
Sbjct: 877 PGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSIL 936
Query: 774 YSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCD-----DFMGQLLNGRVLFPVNLQL 828
YSC+ GY L G A + CT +G WS AP C+ +C D + + L R ++ Q
Sbjct: 937 YSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMY----QY 992
Query: 829 GAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVC 866
GA V C++G+ L+GS S C + WN + VC
Sbjct: 993 GAVVTLECEDGYMLEGSPQSQC---QSDHQWNPPLAVC 1027
Score = 338 bits (868), Expect = 2e-92
Identities = 220/671 (32%), Positives = 310/671 (46%), Gaps = 72/671 (10%)
Query: 37 PVAWGQCNAPEWLPFARPTNLTDEFE------FPIGTYLNYECRPGY--SGRPFSIICLK 88
PV +C AP P L + E F GT + Y C PGY G SI C
Sbjct: 404 PVCEKECQAP-------PNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEE-SIQCTS 455
Query: 89 NSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQF-GSQIKYSCTKGYRLIGSSSATCII 147
VWT +C+ +C + + QF + SC +GY+L GS C
Sbjct: 456 EGVWTPPVPQCKVAAC----EATGRQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQEC-- 509
Query: 148 SGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFEL 207
T+ W E +C I C PP I NG ++ E+F YG+ VTY CNPG F L
Sbjct: 510 -QGTIPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSL 568
Query: 208 VGEPSIYCTSNDDQVGIWSGPAPQC---IIPNKCTPPNVENGILVSDNRSLFSLNEVVEF 264
+GE +I CTSND + G WSGPAP C ++ +C+ ++ NG +S + + N+ V F
Sbjct: 569 IGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTF 628
Query: 265 RCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFY 324
+C GF +KG +++C+A N W+PE+P C + CQ PP + H T + F G V Y
Sbjct: 629 KCYSGFTLKGSSQIRCKADNTWDPEIPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDY 688
Query: 325 SCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDF 384
+C+PGY L G S+ C P G+WSP+AP CE ++C L L G++V+
Sbjct: 689 TCDPGYLLVGNKSIHCMPSGNWSPSAPRCE-ETCQHVRQSL--------QELPAGSRVEL 739
Query: 385 V---CDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFP 441
V C +G+QL G + C A +W +P+C+ I C PPVI NG+HTG E F
Sbjct: 740 VNTSCQDGYQLTGHAYQMCQDA-ENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFL 798
Query: 442 FGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC---GILGHCQAPDH 498
+G V+Y CD F L+GE ++C SD +G+G WS P+P+C + C P+
Sbjct: 799 YGNEVSYECD------QGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPE- 851
Query: 499 FLFAKLKTQTNASDFPIGTSLKYECRPEY-YGRPFSITCLDNLVWSSPKDVCKRKS---C 554
+ K S + + +C P + I C + W C +K+ C
Sbjct: 852 -VKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNTWVPGVPTCIKKAFIGC 910
Query: 555 KTPPDPVNGMVHV---ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 611
PP NG H I G I YSC G+ L+G + C G WS P C
Sbjct: 911 PPPPKTPNGN-HTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGT---WSQPAPHC 966
Query: 612 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
+ + C P + R+ + YG+VVT C G + L G P C S+
Sbjct: 967 KEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDG------YMLEGSPQSQCQSDHQ- 1019
Query: 672 VGIWSGPAPQC 682
W+ P C
Sbjct: 1020 ---WNPPLAVC 1027
Score = 264 bits (674), Expect = 8e-70
Identities = 222/809 (27%), Positives = 328/809 (40%), Gaps = 114/809 (14%)
Query: 66 GTYLNYECRP-----------GYSGRPFSIICLKNSVWTGAKDRCRRKS----CRNPPDP 110
G+ + Y C P G S ++ K W+G RC + C +P
Sbjct: 298 GSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQIL 357
Query: 111 VNGMVHVIKG-IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLP 169
MV K + + ++C G+ L GS C G W+ P+C++ C P
Sbjct: 358 RGRMVSGQKDRYTYNDTVIFACMFGFTLKGSKQIRCNAQGT---WEPSAPVCEK-ECQAP 413
Query: 170 PTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPA 229
P I NG + F G+ + Y CNPG + LVGE SI CTS G+W+ P
Sbjct: 414 PNILNGQKEDRHMVRFDPGTSIKYSCNPG------YVLVGEESIQCTSE----GVWTPPV 463
Query: 230 PQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPE 289
PQC K L++ + F + V C G+ + G +CQ W E
Sbjct: 464 PQC----KVAACEATGRQLLTKPQHQF-VRPDVNSSCGEGYKLSGSVYQECQGTIPWFME 518
Query: 290 LPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG------YDLRGAASMRCTP 342
+ C + C PPP + + T ++F G V Y+C PG + L G +++RCT
Sbjct: 519 IRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTS 578
Query: 343 ----QGDWSPAAPTCEVK----SCDDFM---GQLLNGRVLFPVNLQLGAKVDFVCDEGFQ 391
+G WS AP C++ C G ++G+ V F C GF
Sbjct: 579 NDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGK---EAPYFYNDTVTFKCYSGFT 635
Query: 392 LKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCD 451
LKGSS C ++ W+ +PVCE+ C SPP + +GRHTG F G TV+YTCD
Sbjct: 636 LKGSSQIRCKA---DNTWDPEIPVCEK-GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCD 691
Query: 452 PHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNAS 511
P + L+G +I C P GN WS APRC CQ + +
Sbjct: 692 P------GYLLVGNKSIHCM--PSGN--WSPSAPRCEET--CQ----------HVRQSLQ 729
Query: 512 DFPIGTSLKY---ECRPEYY--GRPFSITCLD--NLVWSSPKDVCKRKSCKTPPDPVNGM 564
+ P G+ ++ C+ Y G + + C D N +W +CK C PP VNG
Sbjct: 730 ELPAGSRVELVNTSCQDGYQLTGHAYQM-CQDAENGIWFKKIPLCKVIHCHPPPVIVNGK 788
Query: 565 VH--VITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAH--WSTKPPICQRIP----C 616
+ + G+ ++Y C G L+G +C S + H WS P C R P C
Sbjct: 789 HTGMMAENFLYGNEVSYECDQGFYLLGEKKLQC-RSDSKGHGSWSGPSPQCLRSPPVTRC 847
Query: 617 GLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWS 676
P + +G ++ + + +V CNPG F + G I C +++ W
Sbjct: 848 P-NPEVKHGYKLNKTHSAYSHNDIVYVDCNPG------FIMNGSRVIRCHTDNT----WV 896
Query: 677 GPAPQCI---IPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 733
P CI PP NG N + FS + + C G+++ G + C
Sbjct: 897 PGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHE 956
Query: 734 NKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTP 792
W P C V C P D+ ++ + + G V CE GY L G+ +C
Sbjct: 957 GTWSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQS 1016
Query: 793 QGDWSPAAPTCEVKSCDDFMGQLLNGRVL 821
W+P C +S + + G +L
Sbjct: 1017 DHQWNPPLAVCRSRSLAPVLCGIAAGLIL 1045
Score = 175 bits (443), Expect = 5e-43
Identities = 151/534 (28%), Positives = 220/534 (41%), Gaps = 89/534 (16%)
Query: 62 EFPIGTYLNYECRPG-YSGRPFSII------CLKN----SVWTGAKDRCRRK----SCRN 106
+FP GT + Y C PG G FS+I C N W+G C+ C +
Sbjct: 545 DFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSH 604
Query: 107 PPDPVNGMVHVIKGIQ---------FGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNE 157
VH+ G + + + + C G+ L GSS C WD E
Sbjct: 605 --------VHIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADN---TWDPE 653
Query: 158 TPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTS 217
P+C++ C PP + +G N F G V Y C+PG + LVG SI+C
Sbjct: 654 IPVCEK-GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPG------YLLVGNKSIHCMP 706
Query: 218 NDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRR 277
+ G WS AP+C C L + +R E+V CQ G+ + G
Sbjct: 707 S----GNWSPSAPRC--EETCQHVRQSLQELPAGSRV-----ELVNTSCQDGYQLTGHAY 755
Query: 278 VKCQALNK--WEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG 334
CQ W ++P C + C PPP +++ + T +NF G EV Y C+ G+ L G
Sbjct: 756 QMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLG 815
Query: 335 AASMRCTP----QGDWSPAAPTC----EVKSCDDFMGQLLNGRVLFPVNLQLGAK--VDF 384
++C G WS +P C V C + ++ +G L + V
Sbjct: 816 EKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPN--PEVKHGYKLNKTHSAYSHNDIVYV 873
Query: 385 VCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQ---IFCPSPPVIPNGRHTGKPLEVFP 441
C+ GF + GS C ++ W VP C + I CP PP PNG HTG + F
Sbjct: 874 DCNPGFIMNGSRVIRC---HTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFS 930
Query: 442 FGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLF 501
G ++ Y+CD + L+GE+ + CT + G WS PAP C + +C +P +
Sbjct: 931 PGMSILYSCD------QGYLLVGEALLLCTHE----GTWSQPAPHCKEV-NCSSPAD-MD 978
Query: 502 AKLKTQTNASDFPIGTSLKYECRPEYY--GRPFSITCLDNLVWSSPKDVCKRKS 553
K + G + EC Y G P S C + W+ P VC+ +S
Sbjct: 979 GIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQS-QCQSDHQWNPPLAVCRSRS 1031
Score = 100 bits (249), Expect = 1e-20
Identities = 79/327 (24%), Positives = 128/327 (39%), Gaps = 28/327 (8%)
Query: 62 EFPIGT---YLNYECRPGY--SGRPFSIIC-LKNSVWTGAKDRCRRKSCRNPPDPVNGMV 115
E P G+ +N C+ GY +G + + +N +W C+ C PP VNG
Sbjct: 730 ELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKH 789
Query: 116 H--VIKGIQFGSQIKYSCTKGYRLIGSSSATCII-SGDTVIWDNETPICDRIP----CGL 168
+ + +G+++ Y C +G+ L+G C S W +P C R P C
Sbjct: 790 TGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCP- 848
Query: 169 PPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGP 228
P + +G ++ + + +V CNPG F + G I C +++ W
Sbjct: 849 NPEVKHGYKLNKTHSAYSHNDIVYVDCNPG------FIMNGSRVIRCHTDNT----WVPG 898
Query: 229 APQCI---IPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK 285
P CI PP NG N + FS + + C G+++ G + C
Sbjct: 899 VPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGT 958
Query: 286 WEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQG 344
W P C V C P D+ ++ + + G V CE GY L G+ +C
Sbjct: 959 WSQPAPHCKEVNCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQSDH 1018
Query: 345 DWSPAAPTCEVKSCDDFMGQLLNGRVL 371
W+P C +S + + G +L
Sbjct: 1019 QWNPPLAVCRSRSLAPVLCGIAAGLIL 1045
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 401 bits (1030), Expect = e-111
Identities = 468/1856 (25%), Positives = 684/1856 (36%), Gaps = 337/1856 (18%)
Query: 101 RKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGD-TVIWDNETP 159
R+SC +P + +NG + + GS + Y C GY L G S+ TCI+ D W+ P
Sbjct: 1594 RESCFDPGNIMNG-TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1652
Query: 160 ICDRIPCGLPPTITNGDFISTNR-ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSN 218
C PCG T + G +S N +N+ G + C K F + G+ + TS
Sbjct: 1653 SC-HAPCGSRSTGSEGTVLSPNYPKNYSVG----HNCVYSIAVPKEFVVFGQFVFFQTSL 1707
Query: 219 DDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRV 278
D V ++ GP Q + + + + + +S + + F KG V
Sbjct: 1708 HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQI-----TIRFTSVGPITAKGFHFV 1762
Query: 279 KCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASM 338
QA+ + CS V +P +R + F+ G V + C PGY L G+ ++
Sbjct: 1763 Y-QAVPRTSST--QCSSVPEP-------RFGRRIGNEFAVGSSVLFDCNPGYILHGSIAI 1812
Query: 339 RC----TPQGDWSPAAPTCEVKSCDDFM----GQLLNGRVLFPVNLQLGAKVDFVCDEGF 390
RC W+ + PTC + C + G +L+ P + L EG
Sbjct: 1813 RCETVPNSLAQWNDSLPTC-IVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGA 1871
Query: 391 QLKGSSASYCVLAGMESL-----------------------------------WNSSVPV 415
++ S+ +SL + S + V
Sbjct: 1872 GIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISV 1931
Query: 416 CEQIF-----------CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIG 464
F CP P +G G + + G V++ CD + L G
Sbjct: 1932 SAAGFHLEYTAIGLDSCPEPQTPSSGIKIG---DRYMVGDVVSFQCD------QGYSLQG 1982
Query: 465 ESTIRCTSDPQGNGVWSSPAPRC------------GILGHCQAPD--------------- 497
S I C P W+ P P C G++ P
Sbjct: 1983 HSHITCMPGPVRR--WNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLP 2040
Query: 498 -----HFLFAKLKTQT-------NASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSP 545
H F T+T + T + P+ FS T +L + S
Sbjct: 2041 IGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSD 2100
Query: 546 KDVCKR-----------KSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAE 594
K+ +SC P NG V + D VG I++ C G+ LIG+S+
Sbjct: 2101 YSQNKQGFHIVYQAYQLQSCPDPRPFRNGFV-IGNDFTVGQTISFECFPGYTLIGNSALT 2159
Query: 595 CILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTY---RCNPGSGG 651
C L G + +W+ P C+ + CG T NG S + + + R PG+G
Sbjct: 2160 C-LHGVSRNWNHPLPRCEAL-CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGI 2217
Query: 652 RKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEV 711
F ++ IY D + +W GP P + + S++S +
Sbjct: 2218 YINFTVLQTEPIY-----DFITVWDGPDQ--------NSPQIGQFSGNTALESVYSTSNQ 2264
Query: 712 VEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQE 771
+ + F G + A RVCQPPP V +AE D D F G
Sbjct: 2265 ILIKFHSDFTTSGFFVLSYHAYQ---------LRVCQPPPPVPNAEILTED-DEFEIGDI 2314
Query: 772 VFYSCEPGYDLRGAASMRCT--PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP------ 823
+ Y C PG+ L G A + C + A P C+V + + G +L P
Sbjct: 2315 IRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSY 2374
Query: 824 VNLQLGAKVDFVCDEGFQL-------------------KGSSASYCVLAGMESLWNSSVP 864
NLQ+ A ++G+ + G + VL + ++S+
Sbjct: 2375 PNLQMCA-WSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFN 2433
Query: 865 VCEQ-------------------------IFCPSPPVIPNG---RHTGKPLEVFPFGKAV 896
+ +C +P P+G TG L V
Sbjct: 2434 ITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQL-----NSVV 2488
Query: 897 NYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKT 956
+ C DRG F L+G+S+ C G W +P P C + C P K
Sbjct: 2489 RWAC----DRG--FRLVGKSSAVCRKSSYGYHAWDAPVPACQAIS-CGIP--------KA 2533
Query: 957 QTN----ASDFPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKDV--CKRKSCKTP 1007
TN +D+ +GT + Y C Y +T C + WS+ C SC
Sbjct: 2534 PTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGEL 2593
Query: 1008 PDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCG 1067
P P NG + T GS ++C G L+G + EC+ SG WS C CG
Sbjct: 2594 PTPPNGN-KIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSG---LWSESETRCLAGHCG 2649
Query: 1068 LPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSG 1127
+P I NG I EN+ Y V Y+CN G F L+G C + + WSG
Sbjct: 2650 IPELIVNGQVIG---ENYGYRDTVVYQCNPG------FRLIGSSVRICQQDHN----WSG 2696
Query: 1128 PAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWE 1187
P C +P C P + I + + F+ N+VV F C G++M+GP + +CQA +W
Sbjct: 2697 QLPSC-VPVSCGHPG--SPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWS 2753
Query: 1188 PELPSCSRVCQPPPEILHGEHTPS--HQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD 1245
P C V P I S NF+ G VFY C PGY L G++ L C P G
Sbjct: 2754 HPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQ 2813
Query: 1246 WSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGM 1305
W P C + C +P VL G+ V + C L G S C L G
Sbjct: 2814 WDKPLPECIMIDCGH--PGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGH 2871
Query: 1306 RSLWNNSVPVCEHI---FCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNL 1362
W+ S P C C +P H + + Y CD + L
Sbjct: 2872 ---WSGSQPHCSGDATGTCGDPG---TPGHGSRQESNFRTKSTVRYACD------TGYIL 2919
Query: 1363 IGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSL 1422
G C + NG W+ P C+ +V+ G+ T I+ F +S+
Sbjct: 2920 HGSEERTCLA----NGSWTGRQPECK-AVQCGNPGTTAN----GKVFRIDGTTF--SSSV 2968
Query: 1423 NYECRPGYFGKMFSI-SCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVN 1481
Y C GY S+ C N WS NC SCG P P NG+ D G V+
Sbjct: 2969 IYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGL-RYGDDYVVGQNVS 3027
Query: 1482 YSCNEGF--RLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFH 1539
Y C G+ L GS TC ++G TW P C ++C PP ISNG T+F
Sbjct: 3028 YMCQPGYTMELNGSRIRTCTING---TWSGVMPTCRAVTCPTPPQISNGRL---EGTNFD 3081
Query: 1540 NGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENA 1599
G ++Y C G +EL + C G WS P+C+ C P +
Sbjct: 3082 WGFSISYICSPG------YELSFPAVLTCVGN----GTWSGEVPQCL-PKFCGDPGIPAQ 3130
Query: 1600 IRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHC----SRVCQPPPE 1655
+ G +SF +E + F C F++VGS T CQ +G W PHC C+ P
Sbjct: 3131 GKREG-KSFIYQSE-VSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGV 3188
Query: 1656 ILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFL 1715
HG ++ F G V + C+ + L+G+ + C P WS P C SC
Sbjct: 3189 PRHGSQ--NNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQ-- 3244
Query: 1716 GQLPHGRVLLPLNL-QLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCE 1770
+ P ++ ++L G + + C GF L G H V W VP+CE
Sbjct: 3245 PETPAHANVVGMDLPSHGYTLIYTCQPGFFLAG-GTEHRVCRSDNT-WTGKVPICE 3298
Score = 305 bits (780), Expect = 4e-82
Identities = 267/919 (29%), Positives = 381/919 (41%), Gaps = 110/919 (11%)
Query: 43 CNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYS--GRPFSIICLKNS----VWTGAK 96
C+ PE P + T + + + + C G+ G+ S +C K+S W
Sbjct: 2465 CSTPESPPHGYIISQTGG---QLNSVVRWACDRGFRLVGKS-SAVCRKSSYGYHAWDAPV 2520
Query: 97 DRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWD- 155
C+ SC P P NG + + G+++ Y C GYRL T + D W
Sbjct: 2521 PACQAISCGIPKAPTNGGI-LTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGT-WSN 2578
Query: 156 -NETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIY 214
N+TP C I CG PT NG+ I T YGS + C+ G F LVG
Sbjct: 2579 HNKTPRCVVISCGELPTPPNGNKIGTQTS---YGSTAIFTCDLG------FMLVGSAVRE 2629
Query: 215 CTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKG 274
C S+ G+WS +C+ + P + NG ++ +N + + V ++C PGF + G
Sbjct: 2630 CLSS----GLWSESETRCLAGHCGIPELIVNGQVIGEN---YGYRDTVVYQCNPGFRLIG 2682
Query: 275 PRRVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLR 333
CQ + W +LPSC V C P ++ RT + NF+ V +SC GY ++
Sbjct: 2683 SSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYG-RTSGNGFNFN--DVVTFSCNIGYLMQ 2739
Query: 334 GAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPV---NLQLGAKVDFVCDEGF 390
G +C WS P C+V +C D G N + + N G V + C+ G+
Sbjct: 2740 GPTKAQCQANRQWSHPPPMCKVVNCSD-PGIPANSKRESKIEHGNFTYGTVVFYDCNPGY 2798
Query: 391 QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTC 450
L GSS C G W+ +P C I C P V PN +G E + FG TV+Y+C
Sbjct: 2799 FLFGSSVLICQPNGQ---WDKPLPECIMIDCGHPGVPPNAVLSG---EKYTFGSTVHYSC 2852
Query: 451 DPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC-----GILGHCQAPDHFLFAKLK 505
L+G+S+ C Q NG WS P C G G P H
Sbjct: 2853 T------GKRSLLGQSSRTC----QLNGHWSGSQPHCSGDATGTCGDPGTPGH------- 2895
Query: 506 TQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNG 563
S+F ++++Y C Y +G TCL N W+ + CK C P NG
Sbjct: 2896 GSRQESNFRTKSTVRYACDTGYILHGSE-ERTCLANGSWTGRQPECKAVQCGNPGTTANG 2954
Query: 564 MVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIA 623
V I S + YSC G+ L G S +C +G WS P C I CG P A
Sbjct: 2955 KVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGT---WSGTLPNCTIISCGDPGIPA 3011
Query: 624 NGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCI 683
NG +++ G V+Y C PG EL G CT N G WSG P C
Sbjct: 3012 NG---LRYGDDYVVGQNVSYMCQPG----YTMELNGSRIRTCTIN----GTWSGVMPTCR 3060
Query: 684 IPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC 743
TPP + NG L N F + + C PG+ + P + C W E+P C
Sbjct: 3061 AVTCPTPPQISNGRLEGTN---FDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQC 3117
Query: 744 -SRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPT 802
+ C P + +R+ +F EV +SC + L G+++ C G WS ++P
Sbjct: 3118 LPKFCGDPG---IPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPH 3174
Query: 803 C---EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLW 859
C SC++ G +G Q+G+ V F C +G L+GS+ C+ + W
Sbjct: 3175 CIEPTQTSCEN-PGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCL---PDLTW 3230
Query: 860 NSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIR 919
+ P C C P + G +++ G + YTC P F L G + R
Sbjct: 3231 SGIQPECIPHSCKQPETPAHANVVG--MDLPSHGYTLIYTCQP------GFFLAGGTEHR 3282
Query: 920 -CTSDPQGNGVWSSPAPRC 937
C SD W+ P C
Sbjct: 3283 VCRSD----NTWTGKVPIC 3297
Score = 291 bits (744), Expect = 6e-78
Identities = 240/829 (28%), Positives = 335/829 (40%), Gaps = 96/829 (11%)
Query: 62 EFPIGTYLNYECRPGY---SGRPFSIICLKNSVWTGAKD--RCRRKSCRNPPDPVNGMVH 116
++ +GT + Y C GY S + +C + W+ RC SC P P NG
Sbjct: 2543 DYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGN-K 2601
Query: 117 VIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGD 176
+ +GS ++C G+ L+GS+ C+ SG +W C CG+P I NG
Sbjct: 2602 IGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSG---LWSESETRCLAGHCGIPELIVNGQ 2658
Query: 177 FISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPN 236
I EN+ Y V Y+CNPG F L+G C + + WSG P C+ P
Sbjct: 2659 VIG---ENYGYRDTVVYQCNPG------FRLIGSSVRICQQDHN----WSGQLPSCV-PV 2704
Query: 237 KCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 296
C P + I + + F+ N+VV F C G++M+GP + +CQA +W P C V
Sbjct: 2705 SCGHPG--SPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVV 2762
Query: 297 -CQPPPDVLHAERTQR-DKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCE 354
C P +++R + + NF+ G VFY C PGY L G++ + C P G W P C
Sbjct: 2763 NCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECI 2822
Query: 355 VKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVP 414
+ C + VL G+ V + C L G S+ C L G W+ S P
Sbjct: 2823 MIDCGH--PGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGH---WSGSQP 2877
Query: 415 VC--EQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTS 472
C + P P H + F TV Y CD T + L G C +
Sbjct: 2878 HCSGDATGTCGDPGTPG--HGSRQESNFRTKSTVRYACD------TGYILHGSEERTCLA 2929
Query: 473 DPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPI-----GTSLKYECRPEY 527
NG W+ P C + C P T N F I +S+ Y C Y
Sbjct: 2930 ----NGSWTGRQPECKAV-QCGNPG--------TTANGKVFRIDGTTFSSSVIYSCMEGY 2976
Query: 528 -YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGH- 585
P C N WS C SC P P NG+ + D VG ++Y C G+
Sbjct: 2977 ILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYG-DDYVVGQNVSYMCQPGYT 3035
Query: 586 -RLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYR 644
L G C ++G WS P C+ + C PP I+NG T NF +G ++Y
Sbjct: 3036 MELNGSRIRTCTINGT---WSGVMPTCRAVTCPTPPQISNGRLEGT---NFDWGFSISYI 3089
Query: 645 CNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNR- 703
C+PG +EL + C N G WSG PQC +P C P GI R
Sbjct: 3090 CSPG------YELSFPAVLTCVGN----GTWSGEVPQC-LPKFCGDP----GIPAQGKRE 3134
Query: 704 -SLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC----SRVCQPPPDVLHAER 758
F V F C F++ G CQA W P C C+ P H
Sbjct: 3135 GKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHG-- 3192
Query: 759 TQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNG 818
+Q + F G V + C+ G+ L+G+ + C P WS P C SC +
Sbjct: 3193 SQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQ-PETPAHA 3251
Query: 819 RVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCE 867
V+ G + + C GF L G + + ++ W VP+CE
Sbjct: 3252 NVVGMDLPSHGYTLIYTCQPGFFLAGGTEHR--VCRSDNTWTGKVPICE 3298
Score = 286 bits (731), Expect = 2e-76
Identities = 440/1946 (22%), Positives = 692/1946 (35%), Gaps = 382/1946 (19%)
Query: 188 GSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGI 247
GS + Y CNPG + L G + C + + + W P P CI +G
Sbjct: 1270 GSTIIYGCNPG------YTLHGSSLLKCMTGERRA--WDYPLPSCIAECGGRFKGESSGR 1321
Query: 248 LVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPD----- 302
++S N + RC + V Q L RV PP+
Sbjct: 1322 ILSPGYPFPYDNNL---RCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLL 1378
Query: 303 --------------VLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSP 348
L+ Q D D FY + G+ ++ ++S+ + P
Sbjct: 1379 KEISGSLIPEGIHSTLNIVTIQFDTD--------FYISKSGFAIQFSSSVATACR---DP 1427
Query: 349 AAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESL 408
P ++ D GR + G V F CD G++L+G C+
Sbjct: 1428 GVPMNGTRNGD--------GR-------EPGDTVVFQCDPGYELQGEERITCIQVENRYF 1472
Query: 409 WNSSVPVCEQIFCPSPPVIP-NGRHTGKPLEV--------FPFGKTVNYTCDPHPDRGTS 459
W S PVC + P G TG + +P + ++T + D S
Sbjct: 1473 WQPSPPVC---------IAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVIS 1523
Query: 460 FDLIGESTIRCTSDPQGNG--VWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGT 517
I S +P + ++ P ++G Q +KL + +S +
Sbjct: 1524 LAFISFSI-----EPNYDFLYIYDGPDSNSPLIGSFQD------SKLPERIESSSNTMHL 1572
Query: 518 SLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRI 577
+ + + Y G F + L R+SC P + +NG + D ++GS +
Sbjct: 1573 AFRSDGSVSYTG--FHLEYKAKL----------RESCFDPGNIMNG-TRLGMDYKLGSTV 1619
Query: 578 NYSCTTGHRLIGHSSAECILSGNAAH-WSTKPPICQRIPCGLPPTIANGDFISTNR-ENF 635
Y C G+ L G+S+ CI+ + W+ P C PCG T + G +S N +N+
Sbjct: 1620 TYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHA-PCGSRSTGSEGTVLSPNYPKNY 1678
Query: 636 HYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVEN 695
G + C K F + G+ + TS D V ++ GP Q + + + +
Sbjct: 1679 SVG----HNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGE 1734
Query: 696 GILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLH 755
+ +S + + F KG V QA+ + CS V +P
Sbjct: 1735 SLPLSSGNQI-----TIRFTSVGPITAKGFHFVY-QAVPRTSST--QCSSVPEP------ 1780
Query: 756 AERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRC----TPQGDWSPAAPTCEVKSCDDF 811
+R + F+ G V + C PGY L G+ ++RC W+ + PTC + C
Sbjct: 1781 -RFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC-IVPCGGI 1838
Query: 812 M----GQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESL--------- 858
+ G +L+ P + L EG ++ S+ +SL
Sbjct: 1839 LTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNN 1898
Query: 859 --------------------------WNSSVPVCEQIF-----------CPSPPVIPNGR 881
+ S + V F CP P +G
Sbjct: 1899 APRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGI 1958
Query: 882 HTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC---- 937
G + + G V++ CD + L G S I C P W+ P P C
Sbjct: 1959 KIG---DRYMVGDVVSFQCDQ------GYSLQGHSHITCMPGPVRR--WNYPIPICLAQC 2007
Query: 938 --------GILGHCQAPD--------------------HFLFAKLKTQT-------NASD 962
G++ P H F T+T +
Sbjct: 2008 GGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGS 2067
Query: 963 FPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKR-----------KSCKTPPDPV 1011
T + P+ FS T +L + S K+ +SC P
Sbjct: 2068 SETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFR 2127
Query: 1012 NGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPT 1071
NG V + D VG I++ C G+ LIG+S+ C L G + +W+ P C+ + CG T
Sbjct: 2128 NGFV-IGNDFTVGQTISFECFPGYTLIGNSALTC-LHGVSRNWNHPLPRCEAL-CGGNIT 2184
Query: 1072 IANGDFISTNRENFHYGSVVTYRCNLGSRGRKV---FELVGEPSIYCTSNDDQVGIWSGP 1128
NG S + + + G + F ++ IY D + +W GP
Sbjct: 2185 AMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIY-----DFITVWDGP 2239
Query: 1129 APQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 1188
P + + S++S + + + F G + A
Sbjct: 2240 DQNS--------PQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQL--- 2288
Query: 1189 ELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSP 1248
RVCQPPP + + E + D F G + Y C PG+ L G A L
Sbjct: 2289 ------RVCQPPPPVPNAEIL-TEDDEFEIGDIIRYQCLPGFTLVGNAIL---------- 2331
Query: 1249 EAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVL-VGMRS 1307
C + G P +VL P N + G+ ++ C + +
Sbjct: 2332 ---TCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEK 2388
Query: 1308 LWNNSVPV----CEHIFCPNPPAILNGRHTGTP-----SGDIPYGKEISYTCDPHPDRGM 1358
+N ++ V E F + + +G + +P SGD Y + T + H
Sbjct: 2389 GYNITMFVEFFQTEKEF--DVLQVYDGPNIQSPVLISLSGD--YSSAFNITSNGH----- 2439
Query: 1359 TFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPV 1418
E ++ ++D HGN + A +C TPE P I+ +
Sbjct: 2440 ------EVFLQWSAD-HGNN-----KKGFRIRYIAFYCSTPESPPHG---YIISQTGGQL 2484
Query: 1419 GTSLNYECRPGY--FGKMFSI---SCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTD 1473
+ + + C G+ GK ++ S W + C+ SCG P P NG + + TD
Sbjct: 2485 NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGI-LTTD 2543
Query: 1474 TQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDK--KAPICEIISCEPPPTISNGDFY 1531
G+ V Y CN+G+RL TT + + TW K P C +ISC PT NG+
Sbjct: 2544 YLVGTRVTYFCNDGYRLSSKELTTAVCQSDG-TWSNHNKTPRCVVISCGELPTPPNGNKI 2602
Query: 1532 SNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKC 1591
+TS+ G+ + C G F LVG C S G+WS RC++ + C
Sbjct: 2603 GT-QTSY--GSTAIFTCDLG------FMLVGSAVRECLSS----GLWSESETRCLAGH-C 2648
Query: 1592 TAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-C 1650
PE+ +V G + + + ++C PGF ++GS CQ + W +LP C V C
Sbjct: 2649 GIPELIVNGQVIGEN--YGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSC 2706
Query: 1651 QPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKS 1710
P ++G + + F+ V +SC Y ++G C WS P C V +
Sbjct: 2707 GHPGSPIYGR---TSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVN 2763
Query: 1711 CDD--------FLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALW 1762
C D ++ HG N G V + C+ G+ L G S C G W
Sbjct: 2764 CSDPGIPANSKRESKIEHG------NFTYGTVVFYDCNPGYFLFGSSVLICQPNGQ---W 2814
Query: 1763 NSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIR 1822
+ +P C I C +P N +G + +G + Y+C +L+G+SS
Sbjct: 2815 DKPLPECIMIDCGHPGVPPNAVLSGEKY---TFGSTVHYSCTGKR------SLLGQSSRT 2865
Query: 1823 CTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYL 1882
C Q NG WS P C C P +G S + T+ Y CD GY+
Sbjct: 2866 C----QLNGHWSGSQPHCSGDATGTCGDPGTPGHG---SRQESNFRTKSTVRYACDTGYI 2918
Query: 1883 LVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKV--YHYGDYVTLKCED 1940
L G C G W+ CK V C P G + ++ ++ + V C +
Sbjct: 2919 LHGSEERTCLANGSWTGRQPECKAVQCGNP----GTTANGKVFRIDGTTFSSSVIYSCME 2974
Query: 1941 GYTLEGSPWSQCQADDRWDPPLAKCT 1966
GY L G QC A+ W L CT
Sbjct: 2975 GYILSGPSVRQCTANGTWSGTLPNCT 3000
Score = 285 bits (730), Expect = 2e-76
Identities = 255/932 (27%), Positives = 379/932 (40%), Gaps = 113/932 (12%)
Query: 104 CRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISG-DTVIWDNETPICD 162
C P P +G + G Q S ++++C +G+RL+G SSA C S WD P C
Sbjct: 2465 CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2524
Query: 163 RIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 222
I CG+P TNG ++T ++ G+ VTY CN G + L + D
Sbjct: 2525 AISCGIPKAPTNGGILTT---DYLVGTRVTYFCNDG------YRLSSKELTTAVCQSD-- 2573
Query: 223 GIWS--GPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 280
G WS P+C++ + P NG + S S F C GF++ G +C
Sbjct: 2574 GTWSNHNKTPRCVVISCGELPTPPNGNKIGTQTSYGS---TAIFTCDLGFMLVGSAVREC 2630
Query: 281 QALNKW-EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMR 339
+ W E E + C P +++ Q +N+ V Y C PG+ L G++
Sbjct: 2631 LSSGLWSESETRCLAGHCGIPELIVNG---QVIGENYGYRDTVVYQCNPGFRLIGSSVRI 2687
Query: 340 CTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASY 399
C +WS P+C SC G + GR V F C+ G+ ++G + +
Sbjct: 2688 CQQDHNWSGQLPSCVPVSC-GHPGSPIYGRT-SGNGFNFNDVVTFSCNIGYLMQGPTKAQ 2745
Query: 400 CVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGK-PLEVFPFGKTVNYTCDPHPDRGT 458
C W+ P+C+ + C P + N + K F +G V Y C+P
Sbjct: 2746 C---QANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNP------ 2796
Query: 459 SFDLIGESTIRCTSDPQGNGVWSSPAPRCGIL--GHCQAPDHFLFAKLKTQTNASDFPIG 516
+ L G S + C Q NG W P P C ++ GH P + + + K + G
Sbjct: 2797 GYFLFGSSVLIC----QPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEK-------YTFG 2845
Query: 517 TSLKYEC--RPEYYGRPFSITCLDNLVWSSPKDVCK---RKSCKTPPDPVNGMVHVITDI 571
+++ Y C + G+ S TC N WS + C +C P P +G ++
Sbjct: 2846 STVHYSCTGKRSLLGQS-SRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGS-RQESNF 2903
Query: 572 QVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTN 631
+ S + Y+C TG+ L G C+ +G+ W+ + P C+ + CG P T ANG +
Sbjct: 2904 RTKSTVRYACDTGYILHGSEERTCLANGS---WTGRQPECKAVQCGNPGTTANGKVFRID 2960
Query: 632 RENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP 691
F S V Y C G + L G CT+N G WSG P C I + P
Sbjct: 2961 GTTF--SSSVIYSCMEG------YILSGPSVRQCTAN----GTWSGTLPNCTIISCGDPG 3008
Query: 692 NVENGILVSDNRSLFSLNEVVEFRCQPGFVMK--GPRRVKCQALNKWEPELPSCSRV-CQ 748
NG+ D+ + + + V + CQPG+ M+ G R C W +P+C V C
Sbjct: 3009 IPANGLRYGDD---YVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCP 3065
Query: 749 PPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSC 808
PP + + + + NF G + Y C PGY+L A + C G WS P C K C
Sbjct: 3066 TPPQISNG---RLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFC 3122
Query: 809 DD----FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVP 864
D G+ ++ ++V F C+ F L GSS C G W+ S P
Sbjct: 3123 GDPGIPAQGKREGKSFIYQ------SEVSFSCNFPFILVGSSTRICQADG---TWSGSSP 3173
Query: 865 VC---EQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCT 921
C Q C +P V +G FG V H +G L G +T C
Sbjct: 3174 HCIEPTQTSCENPGVPRHGSQNN------TFGFQVGSVVQFHCKKGHL--LQGSTTRTCL 3225
Query: 922 SDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPI-GTSLKYECRPEYY-- 978
D WS P C I C+ P+ A + D P G +L Y C+P ++
Sbjct: 3226 PDL----TWSGIQPEC-IPHSCKQPETPAHANVV----GMDLPSHGYTLIYTCQPGFFLA 3276
Query: 979 GRPFSITCLDNLVWSSPKDVCKRKSCKTPPDP 1010
G C + W+ +C+ S DP
Sbjct: 3277 GGTEHRVCRSDNTWTGKVPICEAGSKILVKDP 3308
Score = 278 bits (711), Expect = 4e-74
Identities = 243/858 (28%), Positives = 342/858 (39%), Gaps = 118/858 (13%)
Query: 1139 TPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ----ALNKWEPELPSCS 1194
TP + +G ++S LN VV + C GF + G C+ + W+ +P+C
Sbjct: 2467 TPESPPHGYIISQTGG--QLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2524
Query: 1195 RV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDL--RGAASLHCTPQGDWSP--E 1249
+ C P +G + ++ G V Y C GY L + + C G WS +
Sbjct: 2525 AISCGIPKAPTNGGILTT---DYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNK 2581
Query: 1250 APRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLW 1309
PRC V SC + L P+G + G+ F CD GF L GS+V C+ G LW
Sbjct: 2582 TPRCVVISCGE-LPTPPNGNKI-GTQTSYGSTAIFTCDLGFMLVGSAVRECLSSG---LW 2636
Query: 1310 NNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIR 1369
+ S C C P I+NG+ G G Y + Y C+P F LIG S
Sbjct: 2637 SESETRCLAGHCGIPELIVNGQVIGENYG---YRDTVVYQCNPG------FRLIGSSVRI 2687
Query: 1370 CTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPG 1429
C D + WS P C + V GH +P + ND + + C G
Sbjct: 2688 CQQDHN----WSGQLPSC-VPVSCGHPGSPIYGRTSGNGFNFNDV-------VTFSCNIG 2735
Query: 1430 YFGK-MFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDT---QFGSTVNYSCN 1485
Y + C N WS C+ +C P P N + +G+ V Y CN
Sbjct: 2736 YLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCN 2795
Query: 1486 EGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCE----PPPTISNGDFYSNNRTSFHNG 1541
G+ L GS C +G WDK P C +I C PP + +G+ Y+ G
Sbjct: 2796 PGYFLFGSSVLICQPNGQ---WDKPLPECIMIDCGHPGVPPNAVLSGEKYTF-------G 2845
Query: 1542 TVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCI--STNKCTAPEVENA 1599
+ V Y C TG L+G+ S C G WS P C +T C P
Sbjct: 2846 STVHYSC-TGKRS-----LLGQSSRTCQLN----GHWSGSQPHCSGDATGTCGDPGT--- 2892
Query: 1600 IRVPGN----RSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPPP 1654
PG+ S F +R+ C G+++ GS C NG W + P C V C P
Sbjct: 2893 ---PGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPG 2949
Query: 1655 EILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDF 1714
+G+ FS V YSC Y L G + CT G WS P CT+ SC D
Sbjct: 2950 TTANGKVFRIDGTTFS--SSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGD- 3006
Query: 1715 LGQLPHGRVLLPLNLQLGAKVSFVCDEGF--RLKGRSASHCVLAGMKALWNSSVPVCEQI 1772
+P + + +G VS++C G+ L G C + G W+ +P C +
Sbjct: 3007 -PGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGT---WSGVMPTCRAV 3062
Query: 1773 FCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGV 1832
CP PP I NGR GT F +G ISY C P ++F + + C GNG
Sbjct: 3063 TCPTPPQISNGRLEGTNF---DWGFSISYICS--PGYELSFPAV----LTCV----GNGT 3109
Query: 1833 WSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCT 1892
WS P+C +P C P G G ++ +S+ C+ ++LVG C
Sbjct: 3110 WSGEVPQC---LPKFCGDPGIPAQGKREG---KSFIYQSEVSFSCNFPFILVGSSTRICQ 3163
Query: 1893 DQGIWSQLDHYCKE---VNCSFPLFMNGISKELEMKKVYHY--GDYVTLKCEDGYTLEGS 1947
G WS +C E +C P G+ + + + G V C+ G+ L+GS
Sbjct: 3164 ADGTWSGSSPHCIEPTQTSCENP----GVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGS 3219
Query: 1948 PWSQCQADDRWDPPLAKC 1965
C D W +C
Sbjct: 3220 TTRTCLPDLTWSGIQPEC 3237
Score = 270 bits (689), Expect = 1e-71
Identities = 242/925 (26%), Positives = 370/925 (40%), Gaps = 117/925 (12%)
Query: 1066 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1125
C P + +G IS + SVV + C+ G F LVG+ S C + W
Sbjct: 2465 CSTPESPPHGYIISQTGGQLN--SVVRWACDRG------FRLVGKSSAVCRKSSYGYHAW 2516
Query: 1126 SGPAPQCIIPNKCTPPNVENG-ILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVK--CQA 1182
P P C + P NG IL +D + + V + C G+ + CQ+
Sbjct: 2517 DAPVPACQAISCGIPKAPTNGGILTTD----YLVGTRVTYFCNDGYRLSSKELTTAVCQS 2572
Query: 1183 LNKWEPE-------LPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGA 1235
W + SC + PP G T S G ++C+ G+ L G+
Sbjct: 2573 DGTWSNHNKTPRCVVISCGELPTPPNGNKIGTQT-------SYGSTAIFTCDLGFMLVGS 2625
Query: 1236 ASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGS 1295
A C G WS RC C + +L + N V + C+ GFRL GS
Sbjct: 2626 AVRECLSSGLWSESETRCLAGHCG--IPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGS 2683
Query: 1296 SVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPD 1355
SV C W+ +P C + C +P + + GR +G + ++++C+
Sbjct: 2684 SVRICQ---QDHNWSGQLPSCVPVSCGHPGSPIYGRTSGN---GFNFNDVVTFSCN---- 2733
Query: 1356 RGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFE 1415
+ + + G + +C + N WS P P C++ +C P + I
Sbjct: 2734 --IGYLMQGPTKAQCQA----NRQWSHPPPMCKVV----NCSDPGIPANSKRESKIEHGN 2783
Query: 1416 FPVGTSLNYECRPGYFGKMFSIS---CLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINT 1472
F GT + Y+C PGYF +F S C N W C CG P P N ++
Sbjct: 2784 FTYGTVVFYDCNPGYF--LFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEK 2841
Query: 1473 DTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICE---IISCEPPPTISNGD 1529
T FGSTV+YSC L+G S TC ++G+ W P C +C P T +G
Sbjct: 2842 YT-FGSTVHYSCTGKRSLLGQSSRTCQLNGH---WSGSQPHCSGDATGTCGDPGTPGHG- 2896
Query: 1530 FYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTN 1589
S ++F + V Y C TG + L G C + G W+ P C +
Sbjct: 2897 --SRQESNFRTKSTVRYACDTG------YILHGSEERTCLAN----GSWTGRQPECKAV- 2943
Query: 1590 KCTAPEVE---NAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHC 1646
+C P R+ G T + + + C G+++ G QC NG W LP+C
Sbjct: 2944 QCGNPGTTANGKVFRIDGT----TFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC 2999
Query: 1647 SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSY--DLRGAASLHCTPQGDWSPEAP 1704
+ + P I + L + D++ GQ V Y C+P Y +L G+ CT G WS P
Sbjct: 3000 TIISCGDPGI--PANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMP 3057
Query: 1705 RCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNS 1764
C +C Q+ +GR L N G +S++C G+ L + CV G W+
Sbjct: 3058 TCRAVTCPT-PPQISNGR-LEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGT---WSG 3112
Query: 1765 SVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCT 1824
VP C FC +P G+ G F Y E+S++C+ F L+G S+ C
Sbjct: 3113 EVPQCLPKFCGDPGIPAQGKREGKSF---IYQSEVSFSCN------FPFILVGSSTRICQ 3163
Query: 1825 SDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLV 1884
+D G WS +P C +C +P ++G + + G + + C G+LL
Sbjct: 3164 AD----GTWSGSSPHCIEPTQTSCENPGVPRHGSQ--NNTFGFQVGSVVQFHCKKGHLLQ 3217
Query: 1885 GKGFIFCTDQGIWSQLDHYCKEVNC---SFPLFMNGISKELEMKKVYHYGDYVTLKCEDG 1941
G C WS + C +C P N + +L +G + C+ G
Sbjct: 3218 GSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLP-----SHGYTLIYTCQPG 3272
Query: 1942 YTLEGSPWSQ-CQADDRWDPPLAKC 1965
+ L G + C++D+ W + C
Sbjct: 3273 FFLAGGTEHRVCRSDNTWTGKVPIC 3297
Score = 80.1 bits (196), Expect = 2e-14
Identities = 93/409 (22%), Positives = 153/409 (37%), Gaps = 99/409 (24%)
Query: 1457 CGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCL-VSGNNVTWDKKAPICE 1515
C P EP NG I +D GSTV +SC+E + L G+ S TC ++ W P+C+
Sbjct: 382 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 440
Query: 1516 IISCE-----PPPTISNGDF---YSNNR------TSFHNGTVVT-----------YQCHT 1550
+ +C P T ++ +F Y +N T+ + V+ Y T
Sbjct: 441 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 500
Query: 1551 GPDGEQLFELVGERSIYCTS-KDDQVGVWSSPPPRCISTN--------KCTAPEVEN-AI 1600
DG ++ + + S D + SS + T+ K E+E +
Sbjct: 501 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 560
Query: 1601 RVPGNRSF-------FTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHC-----SR 1648
PG + F+ +++RF CQ GF ++G ++ CQ N +W +P C S
Sbjct: 561 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSN 620
Query: 1649 VCQPPPEILHGEHTLSHQDNFS--------PGQEVFYSCEPSYDLRGAASLHCTPQGDWS 1700
P +L ++ + +N + PG + S +DL GD S
Sbjct: 621 FTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDGD-S 678
Query: 1701 PEAPRCTVKSCDDFLGQLPHGRVLLPL--------------------------------- 1727
PE+P + + L +L L
Sbjct: 679 PESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPIN 738
Query: 1728 ------NLQLGAKVSFVCDEGF-RLKGRSASHCVLAGMKALWNSSVPVC 1769
N QLG+ +S +C+EGF + +G C+L K +W+ +P C
Sbjct: 739 ARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 787
Score = 71.2 bits (173), Expect = 9e-12
Identities = 82/293 (27%), Positives = 123/293 (41%), Gaps = 33/293 (11%)
Query: 1003 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL-SGNTAHWSTKPPIC 1061
SC P P G+++ T VG +I YSC TG+ L GH CI S NTA W PIC
Sbjct: 177 SCGNPGVPPKGVLYG-TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 235
Query: 1062 Q-RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKV------FELVGEPSIY 1114
+ CG ++G S + N ++ + + G + F++ +
Sbjct: 236 RAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYL 295
Query: 1115 CTSNDDQVGIW-SG-PAPQCIIPNKCTPPNVENGILVSDNR-------SLFSLNEVVEFR 1165
+ IW SG P II NK N V+D+ + + + + ++F+
Sbjct: 296 EIEGSEPPTIWLSGMNIPPPIISNK----NWLRLHFVTDSNHRYRGFSAPYQVKKAIDFK 351
Query: 1166 CQPGFVMKG-PRRVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFY 1224
+ + G K LN E + + S +C P E +G+ S +FS G V +
Sbjct: 352 SRGFKLFPGKDNSNKFSILN--EGGIKTASNLCPDPGEPENGKRIGS---DFSLGSTVQF 406
Query: 1225 SCEPGYDLRGAASLHCTPQGD----WSPEAPRCAVKSCDDFLGQLPHGRVLFP 1273
SC+ Y L+GA S+ C + WS P C VK+C L Q P G P
Sbjct: 407 SCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNL-QGPSGTFTSP 458
Score = 70.5 bits (171), Expect = 2e-11
Identities = 75/279 (26%), Positives = 116/279 (41%), Gaps = 34/279 (12%)
Query: 553 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL-SGNAAHWSTKPPIC 611
SC P P G+++ T VG +I YSC TG+ L GH CI S N A W PIC
Sbjct: 177 SCGNPGVPPKGVLYG-TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 235
Query: 612 Q-RIPCGLPPTIANGDFISTNREN-FHYGSVVTYR--CNPGSGGRKVFELVGEPSIYCTS 667
+ CG ++G S + N +H + T+ PG +F
Sbjct: 236 RAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIF-----TDFQMEE 290
Query: 668 NDDQVGIWSGPAPQCIIPNKCTPPNV---ENGI---LVSDNR-------SLFSLNEVVEF 714
D + I P + PP + +N + V+D+ + + + + ++F
Sbjct: 291 KYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDF 350
Query: 715 RCQPGFVMKG-PRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVF 773
+ + + G K LN E + + S +C PD E +R +FS G V
Sbjct: 351 KSRGFKLFPGKDNSNKFSILN--EGGIKTASNLC---PDPGEPENGKRIGSDFSLGSTVQ 405
Query: 774 YSCEPGYDLRGAASMRCTPQGD----WSPAAPTCEVKSC 808
+SC+ Y L+GA S+ C + WS P C+VK+C
Sbjct: 406 FSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 444
Score = 69.7 bits (169), Expect = 3e-11
Identities = 134/603 (22%), Positives = 207/603 (34%), Gaps = 149/603 (24%)
Query: 1156 FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC-----SRVCQPPPEILHGEHTP 1210
FS +V+ F CQ GF + G + + CQ N+W +P C S P +L ++
Sbjct: 576 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPE 635
Query: 1211 SHQDNFS--------PGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAP----------- 1251
+ +N + PG + S +DL GD SPE+P
Sbjct: 636 GYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDGD-SPESPILGTFTGAEVP 693
Query: 1252 ----------RCAVKSCDDFLGQ------------------LPHGRVLFPLNLQLGAKVS 1283
R ++ G+ +P F N QLG+ +S
Sbjct: 694 SHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSIS 753
Query: 1284 FVCDEGF-RLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDI-- 1340
+C+EGF + +G+ C+L+ + +W+ +P C P G H PSG I
Sbjct: 754 VICEEGFIKTQGTETITCILMDGKVMWSGLIPKC------GAPC---GGHFSAPSGVILS 804
Query: 1341 ---PYGKEISYTC------DPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSV 1391
P + S C +P +TF + H SP L
Sbjct: 805 PGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSP-----LLG 859
Query: 1392 RAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDN 1451
+ P QF F+S ++F + + T+ N G+ + + SV N
Sbjct: 860 SYNGTQVP-QFLFSS-----SNFIYLLFTTDNSRSNNGF-----------KIHYESVTVN 902
Query: 1452 CRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKA 1511
SC P P +G D GSTV++SC+ G+RL C N W
Sbjct: 903 --TYSCLDPGIPVHGR-RYGHDFSIGSTVSFSCDSGYRLSHEEPLLC---EKNHWWSHPL 956
Query: 1512 PICEIIS----CEPPPTISN---GDFYSNN-----RTSFHNGTVVTYQCHT-GPDGEQLF 1558
P C+ + P TI + +FY N+ +G V + HT + +
Sbjct: 957 PTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDY 1016
Query: 1559 ELVGERSIYCTSKDDQVGVWSSPPP--------------RCISTNKCT------------ 1592
L+ E + G S PP R IS +
Sbjct: 1017 LLITENGSFTQPLARLTG--SDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1074
Query: 1593 -APEVENAIRVPGNRSFFT--LTEIIRFRCQPGFVMVGSHTVQCQTNGR--WGPKLPHCS 1647
P + I G+R F + + + F C G+ + G+ + C GR W LP C
Sbjct: 1075 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1134
Query: 1648 RVC 1650
C
Sbjct: 1135 AEC 1137
Score = 68.9 bits (167), Expect = 5e-11
Identities = 74/285 (25%), Positives = 118/285 (41%), Gaps = 34/285 (11%)
Query: 97 DRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCII-SGDTVIWD 155
+ + SC NP P G+++ + G +I+YSC GY L G TCI S +T WD
Sbjct: 171 EELQSSSCGNPGVPPKGVLYGTR-FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWD 229
Query: 156 NETPIC-DRIPCGLPPTITNGDFISTNREN-FHYGSVVTYR--CNPGSGGRKVFELVGEP 211
PIC CG ++G S + N +H + T+ PG +F
Sbjct: 230 FPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIF-----T 284
Query: 212 SIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV---ENGI---LVSDNR-------SLFSL 258
D + I P + PP + +N + V+D+ + + +
Sbjct: 285 DFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQV 344
Query: 259 NEVVEFRCQPGFVMKG-PRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFS 317
+ ++F+ + + G K LN E + + S +C PD E +R +FS
Sbjct: 345 KKAIDFKSRGFKLFPGKDNSNKFSILN--EGGIKTASNLC---PDPGEPENGKRIGSDFS 399
Query: 318 PGQEVFYSCEPGYDLRGAASMRCTPQGD----WSPAAPTCEVKSC 358
G V +SC+ Y L+GA S+ C + WS P C+VK+C
Sbjct: 400 LGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 444
Score = 67.8 bits (164), Expect = 1e-10
Identities = 77/295 (26%), Positives = 121/295 (41%), Gaps = 25/295 (8%)
Query: 1450 DNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLV-SGNNVTWD 1508
+ + SCG P P G+++ T G + YSC G+ L G P TC+ S N +WD
Sbjct: 171 EELQSSSCGNPGVPPKGVLY-GTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWD 229
Query: 1509 KKAPICEI-ISCEPPPTISNGDFYSNN-RTSFHNGTVVTYQCHTGPDGEQL------FEL 1560
PIC +C S+G S + +HN T+ P G+ + F++
Sbjct: 230 FPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEP-GDTISLIFTDFQM 288
Query: 1561 VGERSIYCTSKDDQVGVWSS----PPPRCISTNKCTAPEV-ENAIRVPGNRSFFTLTEII 1615
+ + +W S PPP + N V ++ R G + + + + I
Sbjct: 289 EEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAI 348
Query: 1616 RFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEV 1675
F+ + GF + + + + S +C P E +G+ S +FS G V
Sbjct: 349 DFKSR-GFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGS---DFSLGSTV 404
Query: 1676 FYSCEPSYDLRGAASLHCTPQGD----WSPEAPRCTVKSCDDFLGQLPHGRVLLP 1726
+SC+ Y L+GA S+ C + WS P C VK+C L Q P G P
Sbjct: 405 QFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNL-QGPSGTFTSP 458
Score = 65.9 bits (159), Expect = 4e-10
Identities = 203/866 (23%), Positives = 304/866 (35%), Gaps = 179/866 (20%)
Query: 910 FDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSL 969
F+LIGE +I C Q N WS+ P C +F L T P+GT L
Sbjct: 590 FELIGEKSIVC----QENNQWSANIPIC------------IFPCLSNFTA----PMGTVL 629
Query: 970 KYECRPEYYGRPFSITCLDNLV---------------WSSPKDVCKRKSCKTPPDPVNGM 1014
+ PE YG ++ C+ ++ S D K +P P+ G
Sbjct: 630 SPDY-PEGYGN--NLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILG- 685
Query: 1015 VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPC-GLPPTIA 1073
T +V S + + H L A+ +SG + + P G+P
Sbjct: 686 --TFTGAEVPSHLT---SNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIP---- 736
Query: 1074 NGDFISTNR--ENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 1131
I+ R +NF GS ++ C G + G +I C D +V +WSG P+
Sbjct: 737 ----INARRFGDNFQLGSSISVICEEG-----FIKTQGTETITCILMDGKV-MWSGLIPK 786
Query: 1132 CIIPNKCTPP-NVENGILVSDNRSLF---SLNEVVEFRCQPGFVMKGPRRVKCQALNKWE 1187
C P C + +G+++S + SLN +PG +K LN
Sbjct: 787 CGAP--CGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDV 844
Query: 1188 PELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWS 1247
E+ + P +G P + S + ++ + G +H
Sbjct: 845 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGF-KIHY------- 896
Query: 1248 PEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRS 1307
E+ SC D G HGR + + +G+ VSF CD G+RL S +L
Sbjct: 897 -ESVTVNTYSCLD-PGIPVHGR-RYGHDFSIGSTVSFSCDSGYRL---SHEEPLLCEKNH 950
Query: 1308 LWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDI---------PYGKEISYTCDPHPDRGM 1358
W++ +P C+ A+ G G PSG I P ++T D +G+
Sbjct: 951 WWSHPLPTCD--------ALCGGDVRG-PSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV 1001
Query: 1359 TFNLIGESTIRCTSDPHG------NGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPIN 1412
FN T D H NG ++ P R S F + I+
Sbjct: 1002 QFNF---HTFHL-EDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFIS 1057
Query: 1413 DFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINT 1472
DF S++YE F FS LE C P P G I
Sbjct: 1058 DF------SISYEG----FNITFSEYNLE--------------PCEDPGIPQYGS-RIGF 1092
Query: 1473 DTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYS 1532
+ G T+ +SC+ G+RL G+ CL G V W P C + C T + G S
Sbjct: 1093 NFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRV-WSAPLPRC-VAECGASATNNEGILLS 1150
Query: 1533 -NNRTSFHNGTVVTY--QCHTGPD---GEQLFELV-GERSIYCTSKDDQ---VGVWSSPP 1582
N ++ N Y Q G + F L G+ KD +G ++
Sbjct: 1151 PNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGAS 1210
Query: 1583 PRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPK 1642
R + T N + + N E GF +V + +
Sbjct: 1211 MRGL-----TLSSTSNQLWLEFNSDTEGTDE--------GFQLVYTSF-----------E 1246
Query: 1643 LPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCT--PQGDWS 1700
L HC P I + +S Q +F+ G + Y C P Y L G++ L C + W
Sbjct: 1247 LSHCE-----DPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSSLLKCMTGERRAWD 1300
Query: 1701 PEAPRCTVKSCDDFLGQLPHGRVLLP 1726
P C + F G+ GR+L P
Sbjct: 1301 YPLPSCIAECGGRFKGE-SSGRILSP 1325
Score = 65.1 bits (157), Expect = 7e-10
Identities = 152/670 (22%), Positives = 244/670 (36%), Gaps = 117/670 (17%)
Query: 183 ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP- 241
+NF GS ++ C G + G +I C D +V +WSG P+C P C
Sbjct: 744 DNFQLGSSISVICEEG-----FIKTQGTETITCILMDGKV-MWSGLIPKCGAP--CGGHF 795
Query: 242 NVENGILVSDNRSLF---SLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQ 298
+ +G+++S + SLN +PG +K +++ EL
Sbjct: 796 SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIK-------ITFERFQTELNYDVLEVH 848
Query: 299 PPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSC 358
P++L + Q +F S Y L + R + T SC
Sbjct: 849 DGPNLLSP--LLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSC 906
Query: 359 DDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQ 418
D G ++GR + + +G+ V F CD G++L C W+ +P C+
Sbjct: 907 LD-PGIPVHGR-RYGHDFSIGSTVSFSCDSGYRLSHEEPLLCE---KNHWWSHPLPTCDA 961
Query: 419 IFCPSPPVIPNGR--HTGKPLEVFPFGKTVNYTCDPHPDRGTSFD-------------LI 463
+ C P+G G P E +P +T D +G F+ LI
Sbjct: 962 L-CGGDVRGPSGTILSPGYP-EFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLI 1019
Query: 464 GESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYEC 523
E+ + G P G+ G+ +A F+ SDF S+ YE
Sbjct: 1020 TENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFI----------SDF----SISYE- 1064
Query: 524 RPEYYGRPFSITCLD-NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCT 582
F+IT + NL + C+ P P G + + +G + +SC+
Sbjct: 1065 -------GFNITFSEYNL-----------EPCEDPGIPQYGS-RIGFNFGIGDTLTFSCS 1105
Query: 583 TGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNR----ENFHYG 638
+G+RL G S C L G WS P C CG T G +S N EN H
Sbjct: 1106 SGYRLEGTSEIIC-LGGGRRVWSAPLPRCVA-ECGASATNNEGILLSPNYPLNYENNHE- 1162
Query: 639 SVVTYRCNPGSG---GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVEN 695
+ + + G G + F L + D + I+ G + T ++
Sbjct: 1163 CIYSIQVQAGKGINISARTFHL---------AQGDVLKIYDGKDKTTHLLGAFTGASMRG 1213
Query: 696 GILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLH 755
L S + L+ +EF +G + V EL C P +
Sbjct: 1214 LTLSSTSNQLW-----LEFNSDTEGTDEGFQLVYTSF------ELSHCE-----DPGIPQ 1257
Query: 756 AERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT--PQGDWSPAAPTCEVKSCDDFMG 813
D+ +F+ G + Y C PGY L G++ ++C + W P+C + F G
Sbjct: 1258 FGYKISDQGHFA-GSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKG 1316
Query: 814 QLLNGRVLFP 823
+ +GR+L P
Sbjct: 1317 E-SSGRILSP 1325
Score = 63.9 bits (154), Expect = 2e-09
Identities = 107/455 (23%), Positives = 163/455 (35%), Gaps = 100/455 (21%)
Query: 104 CRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCI-ISGDTVIWDNETPICD 162
C +P +P NG + GS +++SC + Y L G+ S TC I+ W + P+C
Sbjct: 382 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 440
Query: 163 RIPC-----GLPPTITNGDF----------------ISTNRE---NFH-YGSVVTY-RCN 196
C G T T+ +F ++TN+ NF + + Y
Sbjct: 441 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 500
Query: 197 PGSGG-----RKVFE-LVGE--PSIYCTSN---------DDQVG-IWSGPAPQCIIPNKC 238
G GG R V + L G P + + + D+ VG + + I C
Sbjct: 501 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 560
Query: 239 TPPNVE-NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC---- 293
P GI D FS +V+ F CQ GF + G + + CQ N+W +P C
Sbjct: 561 GDPGTPLYGIREGDG---FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPC 617
Query: 294 -SRVCQPPPDVLHAERTQRDKDNFS--------PGQEVFYSCEPGYDLRGAASMRCTPQG 344
S P VL + + +N + PG + S +DL G
Sbjct: 618 LSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDG 676
Query: 345 DWSPAAPTCEVKSCDDFMGQLL-NGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLA 403
D SP +P + + L N +L +++F D +G + +Y
Sbjct: 677 D-SPESPILGTFTGAEVPSHLTSNSHIL---------RLEFQADHSMSGRGFNITYNTFG 726
Query: 404 GMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLI 463
E CP P + N R G + F G +++ C+
Sbjct: 727 HNE--------------CPDPGIPINARRFG---DNFQLGSSISVICEE-----GFIKTQ 764
Query: 464 GESTIRCTSDPQGNGVWSSPAPRCGIL--GHCQAP 496
G TI C G +WS P+CG GH AP
Sbjct: 765 GTETITCIL-MDGKVMWSGLIPKCGAPCGGHFSAP 798
Score = 60.8 bits (146), Expect = 1e-08
Identities = 136/619 (21%), Positives = 200/619 (32%), Gaps = 134/619 (21%)
Query: 384 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIF-CPSPPVIPNGRHTGKPLEVFPF 442
F C GF+L G + C + W++++P+C IF C S P G +P
Sbjct: 584 FECQFGFELIGEKSIVCQ---ENNQWSANIPIC--IFPCLSNFTAPMGTVLSPD---YPE 635
Query: 443 GKTVNYTC------DPHPDRGTSF-DLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQA 495
G N C DP SF D ES + G+ S +P G +
Sbjct: 636 GYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD---SPESPILGTFTGAEV 692
Query: 496 PDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCK 555
P H T+ S L+++ GR F+IT + C
Sbjct: 693 PSHL--------TSNSHI---LRLEFQADHSMSGRGFNITY----------NTFGHNECP 731
Query: 556 TPPDPVNGMVHVITDIQVGSRINYSCTTGH-RLIGHSSAECILSGNAAHWSTKPPICQRI 614
P P+N + Q+GS I+ C G + G + CIL WS P C
Sbjct: 732 DPGIPINAR-RFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGA- 789
Query: 615 PCGLPPTIANGDFISTNRENFHYGSVV---TYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
PCG + +G +S ++ S+ PG + FE N D
Sbjct: 790 PCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFE-----RFQTELNYDV 844
Query: 672 VGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ 731
+ + GP + V L S + ++ L R GF + +
Sbjct: 845 LEVHDGPNLLSPLLGSYNGTQVPQ-FLFSSSNFIYLLFTTDNSRSNNGFKI----HYESV 899
Query: 732 ALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 791
+N + C P +H R D FS G V +SC+ GY L + C
Sbjct: 900 TVNTYS---------CLDPGIPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCE 947
Query: 792 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVL-------FPVNLQLGAKVDFVCDEGFQ--- 841
WS PTC+ D G +G +L +P +L VD +G Q
Sbjct: 948 KNHWWSHPLPTCDALCGGDVRGP--SGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNF 1005
Query: 842 --------------------------LKGSSASYCVLAGMESLWNSSVPVCEQIF----- 870
L GS + AG+ + + +
Sbjct: 1006 HTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEG 1065
Query: 871 ------------CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTI 918
C P + G G F G + ++C + + L G S I
Sbjct: 1066 FNITFSEYNLEPCEDPGIPQYGSRIGFN---FGIGDTLTFSC------SSGYRLEGTSEI 1116
Query: 919 RCTSDPQGNGVWSSPAPRC 937
C G VWS+P PRC
Sbjct: 1117 ICLGG--GRRVWSAPLPRC 1133
Score = 60.1 bits (144), Expect = 2e-08
Identities = 104/479 (21%), Positives = 156/479 (32%), Gaps = 110/479 (22%)
Query: 69 LNYECRPGYSGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIK 128
L ++ SGR F+I + C +P P+N Q GS I
Sbjct: 705 LEFQADHSMSGRGFNI----------TYNTFGHNECPDPGIPINAR-RFGDNFQLGSSIS 753
Query: 129 YSCTKGY-RLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHY 187
C +G+ + G+ + TCI+ V+W P C PCG + +G +S ++
Sbjct: 754 VICEEGFIKTQGTETITCILMDGKVMWSGLIPKCG-APCGGHFSAPSGVILSPGWPGYYK 812
Query: 188 GSV---VTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGP---APQCIIPNKCTPP 241
S+ PG + FE N D + + GP +P N P
Sbjct: 813 DSLNCEWVIEAEPGHSIKITFE-----RFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVP 867
Query: 242 NVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPP 301
L S + ++ L R GF + + +N + C P
Sbjct: 868 Q----FLFSSSNFIYLLFTTDNSRSNNGFKI----HYESVTVNTYS---------CLDPG 910
Query: 302 DVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF 361
+H R D FS G V +SC+ GY L + C WS PTC+ D
Sbjct: 911 IPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDV 967
Query: 362 MGQLLNGRVL-------FPVNLQLGAKVDFVCDEGFQ----------------------- 391
G +G +L +P +L VD +G Q
Sbjct: 968 RGP--SGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSF 1025
Query: 392 ------LKGSSASYCVLAGMESLWNSSVPVCEQIF-----------------CPSPPVIP 428
L GS + AG+ + + + C P +
Sbjct: 1026 TQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQ 1085
Query: 429 NGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 487
G G F G T+ ++C + + L G S I C G VWS+P PRC
Sbjct: 1086 YGSRIGFN---FGIGDTLTFSC------SSGYRLEGTSEIICLGG--GRRVWSAPLPRC 1133
Score = 59.7 bits (143), Expect = 3e-08
Identities = 139/652 (21%), Positives = 216/652 (33%), Gaps = 142/652 (21%)
Query: 104 CRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 163
C +P P G + G + +SC+ GYRL G+S C + G +W P C
Sbjct: 1078 CEDPGIPQYGS-RIGFNFGIGDTLTFSCSSGYRLEGTSEIIC-LGGGRRVWSAPLPRC-V 1134
Query: 164 IPCGLPPTITNGDFIS----TNRENFHYGSVVTYRCNPGSG---GRKVFELVGEPSIYCT 216
CG T G +S N EN H + + + G G + F L
Sbjct: 1135 AECGASATNNEGILLSPNYPLNYENNH-ECIYSIQVQAGKGINISARTFHL--------- 1184
Query: 217 SNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 276
+ D + I+ G + T ++ L S + L+ +EF +G +
Sbjct: 1185 AQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLW-----LEFNSDTEGTDEGFQ 1239
Query: 277 RVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAA 336
V EL C P + D+ +F+ G + Y C PGY L G++
Sbjct: 1240 LVYTSF------ELSHCE-----DPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSS 1287
Query: 337 SMRCT--PQGDWSPAAPTCEVKSCDDFMGQLLNGRVL-----FPVNLQLGAKVDFVCDEG 389
++C + W P+C + F G+ +GR+L FP + L D G
Sbjct: 1288 LLKCMTGERRAWDYPLPSCIAECGGRFKGE-SSGRILSPGYPFPYDNNLRCMWMIEVDPG 1346
Query: 390 ------FQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPF- 442
F + AS+ +L +W+ + S +IP G H+ + F
Sbjct: 1347 NIVSLQFLAFDTEASHDIL----RVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFD 1402
Query: 443 ----------------------------------------GKTVNYTCDPHPDRGTSFDL 462
G TV + CDP ++L
Sbjct: 1403 TDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDP------GYEL 1456
Query: 463 IGESTIRCTSDPQGNGVWSSPAPRC---------GILGHCQAPDHFLFAKLKTQTNASDF 513
GE I C + W P C G G +P+ F + D+
Sbjct: 1457 QGEERITCI-QVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPN---FPHPYPHSRDCDW 1512
Query: 514 PIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQV 573
I + Y + FSI + ++ PD + ++ D ++
Sbjct: 1513 TITVNADYVISLAFIS--FSIEPNYDFLY-----------IYDGPDSNSPLIGSFQDSKL 1559
Query: 574 GSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRE 633
RI S T H L S +G + K R C P I NG +
Sbjct: 1560 PERIESSSNTMH-LAFRSDGSVSYTGFHLEYKAK----LRESCFDPGNIMNGTRLGM--- 1611
Query: 634 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIP 685
++ GS VTY C+ G + L G ++ C DD W+ P C P
Sbjct: 1612 DYKLGSTVTYYCDAG------YVLQGYSTLTCIMGDDGRPGWNRALPSCHAP 1657
Score = 54.7 bits (130), Expect = 9e-07
Identities = 61/257 (23%), Positives = 92/257 (35%), Gaps = 50/257 (19%)
Query: 706 FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC-----SRVCQPPPDVLHAERTQ 760
FS +V+ F CQ GF + G + + CQ N+W +P C S P VL + +
Sbjct: 576 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPE 635
Query: 761 RDKDNFS--------PGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM 812
+N + PG + S +DL GD SP +P + +
Sbjct: 636 GYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDGD-SPESPILGTFTGAEVP 693
Query: 813 GQLL-NGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFC 871
L N +L +++F D +G + +Y E C
Sbjct: 694 SHLTSNSHIL---------RLEFQADHSMSGRGFNITYNTFGHNE--------------C 730
Query: 872 PSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 931
P P + N R G + F G +++ C+ G TI C G +WS
Sbjct: 731 PDPGIPINARRFG---DNFQLGSSISVICEE-----GFIKTQGTETITCIL-MDGKVMWS 781
Query: 932 SPAPRCGIL--GHCQAP 946
P+CG GH AP
Sbjct: 782 GLIPKCGAPCGGHFSAP 798
Score = 51.2 bits (121), Expect = 1e-05
Identities = 184/870 (21%), Positives = 288/870 (33%), Gaps = 206/870 (23%)
Query: 825 NLQLGAKVDFVCDEGFQLKGSSASYCV-LAGMESLWNSSVPVCEQIFCPSPPVIPNGRHT 883
+ LG+ V F CDE + L+G+ + C +A + + W+ PVC+ C S P+G T
Sbjct: 397 DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFT 456
Query: 884 GKPLEVFPFGKAVNYTC----------DPHPDRGTSFDL-IGESTIRCTSDPQGNGVWSS 932
FPF N C FDL IG T+ G
Sbjct: 457 SPN---FPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGD----GGEVGD 509
Query: 933 PAPRCGILGHCQAPDHFLFAK----LKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLD 988
P +L PD + L QT+ S +G + Y
Sbjct: 510 PRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNY----------------- 552
Query: 989 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS 1048
K++ +++SC P P+ G + + + C G LIG S C
Sbjct: 553 -------KEI-EKESCGDPGTPLYG-IREGDGFSNRDVLRFECQFGFELIGEKSIVC--- 600
Query: 1049 GNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELV 1108
WS PIC PC T G +S + Y G+ ++ ++
Sbjct: 601 QENNQWSANIPIC-IFPCLSNFTAPMGTVLSPD-----------YPEGYGNNLNCIWTII 648
Query: 1109 GEPS--IYCTSND-------DQVGIWSGPAPQCII------------------------- 1134
+P I+ + ND D + + G +P+ I
Sbjct: 649 SDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQ 708
Query: 1135 ------------------PNKCTPPNVE-NGILVSDNRSLFSLNEVVEFRCQPGFV-MKG 1174
N+C P + N DN F L + C+ GF+ +G
Sbjct: 709 ADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDN---FQLGSSISVICEEGFIKTQG 765
Query: 1175 PRRVKCQALN---KWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYD 1231
+ C ++ W +P C C G H FS V S PG+
Sbjct: 766 TETITCILMDGKVMWSGLIPKCGAPC--------GGH-------FSAPSGVILS--PGWP 808
Query: 1232 LRGAASLHCTPQGDWSPEA-PRCAVK-SCDDFLGQLPHG--------RVLFPLNLQLGAK 1281
SL+C +W EA P ++K + + F +L + +L PL LG+
Sbjct: 809 GYYKDSLNC----EWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPL---LGSY 861
Query: 1282 VSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPV------CEHIFCPNPPAILNGRHTGT 1335
+ F S+ + + S NN + C +P ++GR G
Sbjct: 862 NGTQVPQ-FLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYG- 919
Query: 1336 PSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGH 1395
D G +S++CD + L E + C N WS P P C+ ++ G
Sbjct: 920 --HDFSIGSTVSFSCD------SGYRLSHEEPLLCEK----NHWWSHPLPTCD-ALCGGD 966
Query: 1396 CKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRRK 1455
+ P SP P +F +P + + + GK + D
Sbjct: 967 VRGPSG-TILSPGYP--EF-YPNSLNCTWTVDVTH-GKGVQFN-FHTFHLEDHHDYLLIT 1020
Query: 1456 SCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFR--LIGSPSTTCLVSGNNVTWDKKAPI 1513
G +P + T + T+N FR L + G N+T+ +
Sbjct: 1021 ENGSFTQPLARL----TGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSE---- 1072
Query: 1514 CEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDD 1573
+ CE P G N F G +T+ C +G + L G I C
Sbjct: 1073 YNLEPCEDPGIPQYGSRIGFN---FGIGDTLTFSCSSG------YRLEGTSEIICLGGGR 1123
Query: 1574 QVGVWSSPPPRCISTNKCTAPEVENAIRVP 1603
+ VWS+P PRC++ +A E + P
Sbjct: 1124 R--VWSAPLPRCVAECGASATNNEGILLSP 1151
Score = 49.3 bits (116), Expect = 4e-05
Identities = 70/277 (25%), Positives = 100/277 (36%), Gaps = 34/277 (12%)
Query: 1004 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAEC-ILSGNTAHWSTKPPICQ 1062
C P +P NG + +D +GS + +SC + L G S C ++ A WS P+C+
Sbjct: 382 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 440
Query: 1063 RIPCGLPPTIANGDFISTNRENFHYGS------VVTYRCNLGSRGRKVFELVGEPSIYCT 1116
CG +G F S N F Y S V+T N + FE Y T
Sbjct: 441 VKTCGSNLQGPSGTFTSPNFP-FQYDSNAQCVWVIT-AVNTNKVIQINFEEFDLEIGYDT 498
Query: 1117 SNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 1176
G P + P+ ++VS + ++ + E GF
Sbjct: 499 LTIGDGGEVGDPRTVLQVLTGSFVPD----LIVSMSSQMWLHLQTDESVGSVGF------ 548
Query: 1177 RVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAA 1236
+N E E SC P I G D FS + + C+ G++L G
Sbjct: 549 -----KVNYKEIEKESCGDPGTPLYGIREG-------DGFSNRDVLRFECQFGFELIGEK 596
Query: 1237 SLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFP 1273
S+ C WS P C +F P G VL P
Sbjct: 597 SIVCQENNQWSANIPICIFPCLSNFTA--PMGTVLSP 631
Score = 48.1 bits (113), Expect = 9e-05
Identities = 140/645 (21%), Positives = 212/645 (32%), Gaps = 136/645 (21%)
Query: 1360 FNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVG 1419
F LIGE +I C N WS+ P C FP S +F P+G
Sbjct: 590 FELIGEKSIVCQE----NNQWSANIPICI-------------FPCLS------NFTAPMG 626
Query: 1420 TSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRR-------------------KSCGPP 1460
T L+ + GY + N +W+ + D R K P
Sbjct: 627 TVLSPDYPEGYGNNL-------NCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSP 679
Query: 1461 PEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCE 1520
P G T + S + S + RL + G N+T++ C
Sbjct: 680 ESPILGTF---TGAEVPSHLT-SNSHILRLEFQADHSMSGRGFNITYNTFGHN----ECP 731
Query: 1521 PPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSS 1580
P N + +N F G+ ++ C G + G +I C D +V +WS
Sbjct: 732 DPGIPINARRFGDN---FQLGSSISVICEEG-----FIKTQGTETITCILMDGKV-MWSG 782
Query: 1581 PPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWG 1640
P+C + I PG ++ + C+ H+++ T R+
Sbjct: 783 LIPKCGAPCGGHFSAPSGVILSPGWPGYYKDS----LNCEWVIEAEPGHSIKI-TFERFQ 837
Query: 1641 PKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWS 1700
+L + P +L L + Q +F S Y L +
Sbjct: 838 TELNYDVLEVHDGPNLL--SPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIH 895
Query: 1701 PEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKA 1760
E+ SC D G HGR + +G+ VSF CD G+RL S +L
Sbjct: 896 YESVTVNTYSCLD-PGIPVHGR-RYGHDFSIGSTVSFSCDSGYRL---SHEEPLLCEKNH 950
Query: 1761 LWNSSVPVCE------------QIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDT-HP 1807
W+ +P C+ I P P T D+ +GK + + T H
Sbjct: 951 WWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHL 1010
Query: 1808 DRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSL- 1866
+ + LI E NG ++ P R PP I G Y L
Sbjct: 1011 EDHHDYLLITE-----------NGSFTQPLARL-----TGSDLPPTINAGLYGNFRAQLR 1054
Query: 1867 YLPGMTISYICDPGYLLVGKGFIF--CTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEM 1924
++ +ISY G+ + + C D GI Y + +F +
Sbjct: 1055 FISDFSISY---EGFNITFSEYNLEPCEDPGI----PQYGSRIGFNFGI----------- 1096
Query: 1925 KKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDR--WDPPLAKCTS 1967
GD +T C GY LEG+ C R W PL +C +
Sbjct: 1097 ------GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVA 1135
Score = 47.0 bits (110), Expect = 2e-04
Identities = 68/277 (24%), Positives = 101/277 (36%), Gaps = 34/277 (12%)
Query: 554 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAEC-ILSGNAAHWSTKPPICQ 612
C P +P NG + +D +GS + +SC + L G S C ++ A WS P+C+
Sbjct: 382 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 440
Query: 613 RIPCGLPPTIANGDFISTNRENFHYGS------VVTYRCNPGSGGRKVFELVGEPSIYCT 666
CG +G F S N F Y S V+T N + FE Y T
Sbjct: 441 VKTCGSNLQGPSGTFTSPNFP-FQYDSNAQCVWVIT-AVNTNKVIQINFEEFDLEIGYDT 498
Query: 667 SNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 726
G P + P+ ++VS + ++ + E GF
Sbjct: 499 LTIGDGGEVGDPRTVLQVLTGSFVPD----LIVSMSSQMWLHLQTDESVGSVGF------ 548
Query: 727 RVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAA 786
+N E E SC P + R+ D FS + + C+ G++L G
Sbjct: 549 -----KVNYKEIEKESCGDPGTPLYGI-------REGDGFSNRDVLRFECQFGFELIGEK 596
Query: 787 SMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP 823
S+ C WS P C +F + G VL P
Sbjct: 597 SIVCQENNQWSANIPICIFPCLSNFTAPM--GTVLSP 631
Score = 46.6 bits (109), Expect = 2e-04
Identities = 110/502 (21%), Positives = 165/502 (32%), Gaps = 160/502 (31%)
Query: 737 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ--- 793
E + SC PP VL+ R F G ++ YSC GY L G + C
Sbjct: 172 ELQSSSCGNPGVPPKGVLYGTR-------FDVGDKIRYSCVTGYILDGHPQLTCIANSVN 224
Query: 794 -GDWSPAAPTCEVKSCDDFMGQLLNG------RVLFPVNLQLGAKVDF--VCDEG----- 839
W P C +D G + G FP A + V + G
Sbjct: 225 TASWDFPVPICR---AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISL 281
Query: 840 ----FQLKGSSASYCVLAGME--SLWNSSVPVCEQIFCPSPPVIPN-----------GRH 882
FQ++ Y + G E ++W S + + PP+I N H
Sbjct: 282 IFTDFQME-EKYDYLEIEGSEPPTIWLSGMNI-------PPPIISNKNWLRLHFVTDSNH 333
Query: 883 TGKPLEV-FPFGKAVNYTCD-----PHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPR 936
+ + KA+++ P D F ++ E I+ S+ + R
Sbjct: 334 RYRGFSAPYQVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKR 393
Query: 937 CGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGR-PFSITCLD----NLV 991
G SDF +G+++++ C +Y + SITC
Sbjct: 394 IG----------------------SDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAA 431
Query: 992 WSSPKDVCKRKSCKTPPDPVNG----------------MVHVIT---------------D 1020
WS + VCK K+C + +G V VIT D
Sbjct: 432 WSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFD 491
Query: 1021 IQV---------GSRINYSCTTGHRLIGHSSAECILSGNTAHW---STKPPI-------- 1060
+++ G + T L G + I+S ++ W T +
Sbjct: 492 LEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVN 551
Query: 1061 ---CQRIPCGLPPT----IANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSI 1113
++ CG P T I GD S NR+ V+ + C G FEL+GE SI
Sbjct: 552 YKEIEKESCGDPGTPLYGIREGDGFS-NRD------VLRFECQFG------FELIGEKSI 598
Query: 1114 YCTSNDDQVGIWSGPAPQCIIP 1135
C N+ WS P CI P
Sbjct: 599 VCQENNQ----WSANIPICIFP 616
Score = 45.1 bits (105), Expect = 7e-04
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Query: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 162
+CR+P P+NG + G + G + + C GY L G TCI + W P+C
Sbjct: 1423 ACRDPGVPMNGTRNG-DGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC- 1480
Query: 163 RIPCGLPPTITNGDFISTN 181
PCG T ++G +S N
Sbjct: 1481 IAPCGGNLTGSSGFILSPN 1499
Score = 44.7 bits (104), Expect = 0.001
Identities = 112/503 (22%), Positives = 165/503 (32%), Gaps = 162/503 (32%)
Query: 287 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ--- 343
E + SC PP VL+ R F G ++ YSC GY L G + C
Sbjct: 172 ELQSSSCGNPGVPPKGVLYGTR-------FDVGDKIRYSCVTGYILDGHPQLTCIANSVN 224
Query: 344 -GDWSPAAPTCEVKSCDDFMGQLLNG------RVLFPVNLQLGAKVDF--VCDEG----- 389
W P C +D G + G FP A + V + G
Sbjct: 225 TASWDFPVPICR---AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISL 281
Query: 390 ----FQLKGSSASYCVLAGME--SLWNSSVPVCEQIFCPSPPVIPNG------------- 430
FQ++ Y + G E ++W S + + PP+I N
Sbjct: 282 IFTDFQME-EKYDYLEIEGSEPPTIWLSGMNI-------PPPIISNKNWLRLHFVTDSNH 333
Query: 431 --RHTGKPLEV---FPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAP 485
R P +V F K+ + P D F ++ E I+ S+ +
Sbjct: 334 RYRGFSAPYQVKKAIDF-KSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGK 392
Query: 486 RCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGR-PFSITCLD----NL 540
R G SDF +G+++++ C +Y + SITC
Sbjct: 393 RIG----------------------SDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFA 430
Query: 541 VWSSPKDVCKRKSCKTPPDPVNG----------------MVHVIT--------------- 569
WS + VCK K+C + +G V VIT
Sbjct: 431 AWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEF 490
Query: 570 DIQV---------GSRINYSCTTGHRLIGHSSAECILSGNAAHW---STKPPI------- 610
D+++ G + T L G + I+S ++ W T +
Sbjct: 491 DLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKV 550
Query: 611 ----CQRIPCGLPPT----IANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPS 662
++ CG P T I GD S NR+ V+ + C G FEL+GE S
Sbjct: 551 NYKEIEKESCGDPGTPLYGIREGDGFS-NRD------VLRFECQFG------FELIGEKS 597
Query: 663 IYCTSNDDQVGIWSGPAPQCIIP 685
I C N+ WS P CI P
Sbjct: 598 IVCQENNQ----WSANIPICIFP 616
Score = 41.6 bits (96), Expect = 0.008
Identities = 57/260 (21%), Positives = 99/260 (38%), Gaps = 43/260 (16%)
Query: 1416 FPVGTSLNYECRPGYFGKMF-SISCLENLV----WSSVEDNCRRK-SCGPPPEPFNGMVH 1469
F VG + Y C GY ++C+ N V W CR + +CG +G++
Sbjct: 194 FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGII- 252
Query: 1470 INTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPP------- 1522
+ F + + + + + ++ P T + + ++K EI EPP
Sbjct: 253 --SSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGM 310
Query: 1523 ----PTISNGDFY-------SNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSK 1571
P ISN ++ SN+R + G YQ D F+ G +
Sbjct: 311 NIPPPIISNKNWLRLHFVTDSNHR---YRGFSAPYQVKKAID----FKSRGFKLFPGKDN 363
Query: 1572 DDQVGVWSSPPPRCISTNKCTAP-EVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHT 1630
++ + + + S N C P E EN R+ + F+L ++F C +V+ G+ +
Sbjct: 364 SNKFSILNEGGIKTAS-NLCPDPGEPENGKRIGSD---FSLGSTVQFSCDEDYVLQGAKS 419
Query: 1631 VQCQ----TNGRWGPKLPHC 1646
+ CQ W P C
Sbjct: 420 ITCQRIAEVFAAWSDHRPVC 439
Score = 38.9 bits (89), Expect = 0.052
Identities = 146/721 (20%), Positives = 228/721 (31%), Gaps = 238/721 (33%)
Query: 101 RKSCRNPPDPVNGMVHVIKGIQFGSQ--IKYSCTKGYRLIGSSSATCIISGDTVIWDNET 158
++SC +P P+ G + +G F ++ +++ C G+ LIG S C + W
Sbjct: 557 KESCGDPGTPLYG---IREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ---WSANI 610
Query: 159 PICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPS--IYCT 216
PIC PC T G +S + Y G+ ++ ++ +P I+ +
Sbjct: 611 PIC-IFPCLSNFTAPMGTVLSPD-----------YPEGYGNNLNCIWTIISDPGSRIHLS 658
Query: 217 SND-------DQVGIWSGPAPQCII----------------------------------- 234
ND D + + G +P+ I
Sbjct: 659 FNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGF 718
Query: 235 --------PNKCTPPNVE-NGILVSDNRSLFSLNEVVEFRCQPGFV-MKGPRRVKCQALN 284
N+C P + N DN F L + C+ GF+ +G + C ++
Sbjct: 719 NITYNTFGHNECPDPGIPINARRFGDN---FQLGSSISVICEEGFIKTQGTETITCILMD 775
Query: 285 ---KWEPELPSCSRVC----QPPPDVLHAERTQRDKDNFSPGQEVFY----SCEPGYDLR 333
W +P C C P V+ SPG +Y +CE +
Sbjct: 776 GKVMWSGLIPKCGAPCGGHFSAPSGVI-----------LSPGWPGYYKDSLNCEWVIEAE 824
Query: 334 GAASMRCT-PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFV-----CD 387
S++ T + EV + + LL V L + +F+ D
Sbjct: 825 PGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTD 884
Query: 388 EGFQLKGSSASY-CVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTV 446
G Y V S + +PV +GR G F G TV
Sbjct: 885 NSRSNNGFKIHYESVTVNTYSCLDPGIPV-------------HGRRYGHD---FSIGSTV 928
Query: 447 NYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGIL--GHCQAPDHFLFAKL 504
+++CD + + L E + C + N WS P P C L G + P
Sbjct: 929 SFSCD------SGYRLSHEEPLLC----EKNHWWSHPLPTCDALCGGDVRGPS------- 971
Query: 505 KTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGM 564
GT L PE+Y P S+ C W+
Sbjct: 972 -----------GTILS-PGYPEFY--PNSLNC----TWT--------------------- 992
Query: 565 VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIAN 624
D+ G + ++ T H H +G S P+ + LPPTI
Sbjct: 993 ----VDVTHGKGVQFNFHTFHLEDHHDYLLITENG-----SFTQPLARLTGSDLPPTINA 1043
Query: 625 G---------DFIST-----------------------------NRENFHY--GSVVTYR 644
G FIS +R F++ G +T+
Sbjct: 1044 GLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFS 1103
Query: 645 CNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRS 704
C+ G + L G I C +V WS P P+C+ + N E GIL+S N
Sbjct: 1104 CSSG------YRLEGTSEIICLGGGRRV--WSAPLPRCVAECGASATNNE-GILLSPNYP 1154
Query: 705 L 705
L
Sbjct: 1155 L 1155
Score = 37.0 bits (84), Expect = 0.20
Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 7/66 (10%)
Query: 1848 CPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTD----QGIWSQLDHY 1903
CP P + +NG IG SL G T+ + CD Y+L G I C WS
Sbjct: 382 CPDPGEPENGKRIGSDFSL---GSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPV 438
Query: 1904 CKEVNC 1909
CK C
Sbjct: 439 CKVKTC 444
Score = 33.9 bits (76), Expect = 1.7
Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 1728 NLQLGAKVSFVCDEGFRLKGRSASHCV-LAGMKALWNSSVPVCEQIFC 1774
+ LG+ V F CDE + L+G + C +A + A W+ PVC+ C
Sbjct: 397 DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 444
Score = 33.5 bits (75), Expect = 2.2
Identities = 15/48 (31%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Query: 1928 YHYGDYVTLKCEDGYTLEGSPWSQCQADD--RWDPPLAKCTSRTHDAL 1973
Y GD V+ +C+ GY+L+G C RW+ P+ C ++ A+
Sbjct: 1964 YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAM 2011
Score = 32.7 bits (73), Expect = 3.7
Identities = 21/77 (27%), Positives = 26/77 (33%), Gaps = 9/77 (11%)
Query: 612 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
Q CG P G T F G + Y C G + L G P + C +N
Sbjct: 174 QSSSCGNPGVPPKGVLYGTR---FDVGDKIRYSCVTG------YILDGHPQLTCIANSVN 224
Query: 672 VGIWSGPAPQCIIPNKC 688
W P P C + C
Sbjct: 225 TASWDFPVPICRAEDAC 241
Score = 32.7 bits (73), Expect = 3.7
Identities = 21/77 (27%), Positives = 26/77 (33%), Gaps = 9/77 (11%)
Query: 1062 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQ 1121
Q CG P G T F G + Y C G + L G P + C +N
Sbjct: 174 QSSSCGNPGVPPKGVLYGTR---FDVGDKIRYSCVTG------YILDGHPQLTCIANSVN 224
Query: 1122 VGIWSGPAPQCIIPNKC 1138
W P P C + C
Sbjct: 225 TASWDFPVPICRAEDAC 241
Score = 31.6 bits (70), Expect = 8.3
Identities = 21/71 (29%), Positives = 26/71 (36%), Gaps = 11/71 (15%)
Query: 1187 EPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQ--- 1243
E + SC PP +L+G F G ++ YSC GY L G L C
Sbjct: 172 ELQSSSCGNPGVPPKGVLYGTR-------FDVGDKIRYSCVTGYILDGHPQLTCIANSVN 224
Query: 1244 -GDWSPEAPRC 1253
W P C
Sbjct: 225 TASWDFPVPIC 235
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 399 bits (1025), Expect = e-110
Identities = 476/1934 (24%), Positives = 720/1934 (37%), Gaps = 357/1934 (18%)
Query: 101 RKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGD-TVIWDNETP 159
R+SC +P + +NG + + GS + Y C GY L G S+ TCI+ D W+ P
Sbjct: 1658 RESCFDPGNIMNG-TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1716
Query: 160 ICDRIPCGLPPTITNGDFISTNR-ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSN 218
C PCG T + G +S N +N+ G + C K F + G+ + TS
Sbjct: 1717 SC-HAPCGSRSTGSEGTVLSPNYPKNYSVG----HNCVYSIAVPKEFVVFGQFVFFQTSL 1771
Query: 219 DDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRV 278
D V ++ GP Q + + + + + +S + + F KG V
Sbjct: 1772 HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQI-----TIRFTSVGPITAKGFHFV 1826
Query: 279 KCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASM 338
QA+ + CS V +P +R + F+ G V + C PGY L G+ ++
Sbjct: 1827 Y-QAVPRTSST--QCSSVPEP-------RFGRRIGNEFAVGSSVLFDCNPGYILHGSIAI 1876
Query: 339 RC----TPQGDWSPAAPTCEVKSCDDFM----GQLLNGRVLFPVNLQLGAKVDFVCDEGF 390
RC W+ + PTC + C + G +L+ P + L EG
Sbjct: 1877 RCETVPNSLAQWNDSLPTC-IVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGA 1935
Query: 391 QLKGSSASYCVLAGMESL-----------------------------------WNSSVPV 415
++ S+ +SL + S + V
Sbjct: 1936 GIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISV 1995
Query: 416 CEQIF-----------CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIG 464
F CP P +G G + + G V++ CD + L G
Sbjct: 1996 SAAGFHLEYTAIGLDSCPEPQTPSSGIKIG---DRYMVGDVVSFQCD------QGYSLQG 2046
Query: 465 ESTIRCTSDPQGNGVWSSPAPRC------------GILGHCQAPD--------------- 497
S I C P W+ P P C G++ P
Sbjct: 2047 HSHITCMPGPVRR--WNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLP 2104
Query: 498 -----HFLFAKLKTQT-------NASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSP 545
H F T+T + T + P+ FS T +L + S
Sbjct: 2105 IGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSD 2164
Query: 546 KDVCKR-----------KSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAE 594
K+ +SC P NG V + D VG I++ C G+ LIG+S+
Sbjct: 2165 YSQNKQGFHIVYQAYQLQSCPDPRPFRNGFV-IGNDFTVGQTISFECFPGYTLIGNSALT 2223
Query: 595 CILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTY---RCNPGSGG 651
C L G + +W+ P C+ + CG T NG S + + + R PG+G
Sbjct: 2224 C-LHGVSRNWNHPLPRCEAL-CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGI 2281
Query: 652 RKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEV 711
F ++ IY D + +W GP P + + S++S +
Sbjct: 2282 YINFTVLQTEPIY-----DFITVWDGPDQ--------NSPQIGQFSGNTALESVYSTSNQ 2328
Query: 712 VEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQE 771
+ + F G + A RVCQPPP V +AE D D F G
Sbjct: 2329 ILIKFHSDFTTSGFFVLSYHAYQ---------LRVCQPPPPVPNAEILTED-DEFEIGDI 2378
Query: 772 VFYSCEPGYDLRGAASMRCT--PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP------ 823
+ Y C PG+ L G A + C + A P C+V + + G +L P
Sbjct: 2379 IRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSY 2438
Query: 824 VNLQLGAKVDFVCDEGFQL-------------------KGSSASYCVLAGMESLWNSSVP 864
NLQ+ A ++G+ + G + VL + ++S+
Sbjct: 2439 PNLQMCA-WSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFN 2497
Query: 865 VCEQ-------------------------IFCPSPPVIPNG---RHTGKPLEVFPFGKAV 896
+ +C +P P+G TG L V
Sbjct: 2498 ITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQL-----NSVV 2552
Query: 897 NYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKT 956
+ C DRG F L+G+S+ C G W +P P C + C P K
Sbjct: 2553 RWAC----DRG--FRLVGKSSAVCRKSSYGYHAWDAPVPACQAIS-CGIP--------KA 2597
Query: 957 QTN----ASDFPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKDV--CKRKSCKTP 1007
TN +D+ +GT + Y C Y +T C + WS+ C +C +
Sbjct: 2598 PTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSI 2657
Query: 1008 PDPV--NGMVHVI--TDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQR 1063
+ +G ++ + + +++ +SC G+ +G +S EC+ +G T W + P CQ
Sbjct: 2658 NSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNG-TWSWRNERPYCQI 2716
Query: 1064 IPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVG 1123
I CG PT NG+ I T YGS + C+LG F LVG C S+ G
Sbjct: 2717 ISCGELPTPPNGNKIGTQTS---YGSTAIFTCDLG------FMLVGSAVRECLSS----G 2763
Query: 1124 IWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 1183
+WS +C+ + P + NG ++ +N + + V ++C PGF + G CQ
Sbjct: 2764 LWSESETRCLAGHCGIPELIVNGQVIGEN---YGYRDTVVYQCNPGFRLIGSSVRICQQD 2820
Query: 1184 NKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTP 1242
+ W +LPSC V C P ++G + + F+ V +SC GY ++G C
Sbjct: 2821 HNWSGQLPSCVPVSCGHPGSPIYGR---TSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQA 2877
Query: 1243 QGDWSPEAPRCAVKSCDD--------FLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKG 1294
WS P C V +C D ++ HG N G V + C+ G+ L G
Sbjct: 2878 NRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHG------NFTYGTVVFYDCNPGYFLFG 2931
Query: 1295 SSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHP 1354
SSV C G W+ +P C I C +P G P + G++ ++ H
Sbjct: 2932 SSVLICQPNGQ---WDKPLPECIMIDCGHP---------GVPPNAVLSGEKYTFGSTVHY 2979
Query: 1355 DRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDF 1414
+L+G+S+ C NG WS P C G C P S +
Sbjct: 2980 SCTGKRSLLGQSSRTCQL----NGHWSGSQPHCS-GDATGTCGDPGTPGHGSR----QES 3030
Query: 1415 EFPVGTSLNYECRPGY-FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTD 1473
F +++ Y C GY +CL N W+ + C+ CG P NG V
Sbjct: 3031 NFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDG 3090
Query: 1474 TQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSN 1533
T F S+V YSC EG+ L G C +G TW P C IISC P +NG Y +
Sbjct: 3091 TTFSSSVIYSCMEGYILSGPSVRQCTANG---TWSGTLPNCTIISCGDPGIPANGLRYGD 3147
Query: 1534 NRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTA 1593
+ + G V+Y C G EL G R CT G WS P C + T
Sbjct: 3148 D---YVVGQNVSYMCQPG----YTMELNGSRIRTCTIN----GTWSGVMPTCRAVTCPTP 3196
Query: 1594 PEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHC-SRVCQP 1652
P++ N R+ G F I + C PG+ + + C NG W ++P C + C
Sbjct: 3197 PQISNG-RLEGTN--FDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGD 3253
Query: 1653 PPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRC---TVK 1709
P G+ +F EV +SC + L G+++ C G WS +P C T
Sbjct: 3254 PGIPAQGKR---EGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQT 3310
Query: 1710 SCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVC 1769
SC++ G HG Q+G+ V F C +G L+G + C+ W+ P C
Sbjct: 3311 SCEN-PGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCL---PDLTWSGIQPEC 3366
Query: 1770 EQIFCPNPPAILNGRHTGTPFGDIP-YGKEISYACDTHPDRGMTFNLIGESSIR-CTSDP 1827
C P + G D+P +G + Y C F L G + R C SD
Sbjct: 3367 IPHSCKQPETPAHANVVGM---DLPSHGYTLIYTCQP------GFFLAGGTEHRVCRSD- 3416
Query: 1828 QGNGVWSSPAPRCE 1841
W+ P CE
Sbjct: 3417 ---NTWTGKVPICE 3427
Score = 321 bits (823), Expect = 4e-87
Identities = 274/992 (27%), Positives = 411/992 (41%), Gaps = 124/992 (12%)
Query: 1004 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAH-WSTKPPICQ 1062
C TP P +G + T Q+ S + ++C G RL+G SSA C S H W P CQ
Sbjct: 2529 CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2588
Query: 1063 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQV 1122
I CG+P NG ++T+ + G+ VTY CN G R EL + C S+
Sbjct: 2589 AISCGIPKAPTNGGILTTD---YLVGTRVTYFCNDGYRLSSK-ELT---TAVCQSD---- 2637
Query: 1123 GIWSG--PAPQCIIPNKCTPPNVENGILVSD-----NRSLFSLNEVVEFRCQPGFVMKGP 1175
G WS P+C++ T P++ + IL N S + V F C PG+ GP
Sbjct: 2638 GTWSNHNKTPRCVV---VTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGP 2694
Query: 1176 RRVKC--QALNKWEPELP-----SCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEP 1228
++C W E P SC + PP G T S G ++C+
Sbjct: 2695 ASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQT-------SYGSTAIFTCDL 2747
Query: 1229 GYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDE 1288
G+ L G+A C G WS RC C + +L + N V + C+
Sbjct: 2748 GFMLVGSAVRECLSSGLWSESETRCLAGHCG--IPELIVNGQVIGENYGYRDTVVYQCNP 2805
Query: 1289 GFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISY 1348
GFRL GSSV C W+ +P C + C +P + + GR +G + +++
Sbjct: 2806 GFRLIGSSVRICQ---QDHNWSGQLPSCVPVSCGHPGSPIYGRTSGN---GFNFNDVVTF 2859
Query: 1349 TCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPT 1408
+C+ + + + G + +C + N WS P P C++ +C P +
Sbjct: 2860 SCN------IGYLMQGPTKAQCQA----NRQWSHPPPMCKVV----NCSDPGIPANSKRE 2905
Query: 1409 IPINDFEFPVGTSLNYECRPGYFGKMFSIS---CLENLVWSSVEDNCRRKSCGPPPEPFN 1465
I F GT + Y+C PGYF +F S C N W C CG P P N
Sbjct: 2906 SKIEHGNFTYGTVVFYDCNPGYF--LFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPN 2963
Query: 1466 GMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICE---IISCEPP 1522
++ T FGSTV+YSC L+G S TC ++G+ W P C +C P
Sbjct: 2964 AVLSGEKYT-FGSTVHYSCTGKRSLLGQSSRTCQLNGH---WSGSQPHCSGDATGTCGDP 3019
Query: 1523 PTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPP 1582
T +G S ++F + V Y C TG + L G C + G W+
Sbjct: 3020 GTPGHG---SRQESNFRTKSTVRYACDTG------YILHGSEERTCLAN----GSWTGRQ 3066
Query: 1583 PRCISTNKCTAPEVE---NAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRW 1639
P C + +C P R+ G T + + + C G+++ G QC NG W
Sbjct: 3067 PECKAV-QCGNPGTTANGKVFRIDGT----TFSSSVIYSCMEGYILSGPSVRQCTANGTW 3121
Query: 1640 GPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSY--DLRGAASLHCTPQG 1697
LP+C+ + P I + L + D++ GQ V Y C+P Y +L G+ CT G
Sbjct: 3122 SGTLPNCTIISCGDPGI--PANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTING 3179
Query: 1698 DWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAG 1757
WS P C +C Q+ +GR L N G +S++C G+ L + CV G
Sbjct: 3180 TWSGVMPTCRAVTCPT-PPQISNGR-LEGTNFDWGFSISYICSPGYELSFPAVLTCVGNG 3237
Query: 1758 MKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIG 1817
W+ VP C FC +P G+ G F Y E+S++C+ F L+G
Sbjct: 3238 T---WSGEVPQCLPKFCGDPGIPAQGKREGKSF---IYQSEVSFSCN------FPFILVG 3285
Query: 1818 ESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYIC 1877
S+ C +D G WS +P C +C +P ++G + + G + + C
Sbjct: 3286 SSTRICQAD----GTWSGSSPHCIEPTQTSCENPGVPRHGSQ--NNTFGFQVGSVVQFHC 3339
Query: 1878 DPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNC---SFPLFMNGISKELEMKKVYHYGDYV 1934
G+LL G C WS + C +C P N + +L +G +
Sbjct: 3340 KKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLP-----SHGYTL 3394
Query: 1935 TLKCEDGYTLEGSPWSQ-CQADDRWDPPLAKC 1965
C+ G+ L G + C++D+ W + C
Sbjct: 3395 IYTCQPGFFLAGGTEHRVCRSDNTWTGKVPIC 3426
Score = 299 bits (766), Expect = 2e-80
Identities = 244/822 (29%), Positives = 336/822 (40%), Gaps = 94/822 (11%)
Query: 67 TYLNYECRPGYSGR-PFSIICLKNSVWTGAKDR--CRRKSCRNPPDPVNGMVHVIKGIQF 123
T + + C PGY G P SI CL N W+ +R C+ SC P P NG + +
Sbjct: 2679 TKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGN-KIGTQTSY 2737
Query: 124 GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRE 183
GS ++C G+ L+GS+ C+ SG +W C CG+P I NG I E
Sbjct: 2738 GSTAIFTCDLGFMLVGSAVRECLSSG---LWSESETRCLAGHCGIPELIVNGQVIG---E 2791
Query: 184 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 243
N+ Y V Y+CNPG F L+G C + + WSG P C+ P C P
Sbjct: 2792 NYGYRDTVVYQCNPG------FRLIGSSVRICQQDHN----WSGQLPSCV-PVSCGHPG- 2839
Query: 244 ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPD 302
+ I + + F+ N+VV F C G++M+GP + +CQA +W P C V C P
Sbjct: 2840 -SPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGI 2898
Query: 303 VLHAERTQR-DKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF 361
+++R + + NF+ G VFY C PGY L G++ + C P G W P C + C
Sbjct: 2899 PANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGH- 2957
Query: 362 MGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVC--EQI 419
+ VL G+ V + C L G S+ C L G W+ S P C +
Sbjct: 2958 -PGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGH---WSGSQPHCSGDAT 3013
Query: 420 FCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGV 479
P P H + F TV Y CD T + L G C + NG
Sbjct: 3014 GTCGDPGTPG--HGSRQESNFRTKSTVRYACD------TGYILHGSEERTCLA----NGS 3061
Query: 480 WSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPI-----GTSLKYECRPEY-YGRPFS 533
W+ P C + C P T N F I +S+ Y C Y P
Sbjct: 3062 WTGRQPECKAV-QCGNPG--------TTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSV 3112
Query: 534 ITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGH--RLIGHS 591
C N WS C SC P P NG+ + D VG ++Y C G+ L G
Sbjct: 3113 RQCTANGTWSGTLPNCTIISCGDPGIPANGLRYG-DDYVVGQNVSYMCQPGYTMELNGSR 3171
Query: 592 SAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGG 651
C ++G WS P C+ + C PP I+NG T NF +G ++Y C+PG
Sbjct: 3172 IRTCTINGT---WSGVMPTCRAVTCPTPPQISNGRLEGT---NFDWGFSISYICSPG--- 3222
Query: 652 RKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNR--SLFSLN 709
+EL + C N G WSG PQC +P C P GI R F
Sbjct: 3223 ---YELSFPAVLTCVGN----GTWSGEVPQC-LPKFCGDP----GIPAQGKREGKSFIYQ 3270
Query: 710 EVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC----SRVCQPPPDVLHAERTQRDKDN 765
V F C F++ G CQA W P C C+ P H +Q +
Sbjct: 3271 SEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHG--SQNNTFG 3328
Query: 766 FSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVN 825
F G V + C+ G+ L+G+ + C P WS P C SC + V+
Sbjct: 3329 FQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQ-PETPAHANVVGMDL 3387
Query: 826 LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCE 867
G + + C GF L G + + ++ W VP+CE
Sbjct: 3388 PSHGYTLIYTCQPGFFLAGGTEHR--VCRSDNTWTGKVPICE 3427
Score = 295 bits (755), Expect = 3e-79
Identities = 446/1993 (22%), Positives = 711/1993 (35%), Gaps = 411/1993 (20%)
Query: 188 GSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGI 247
GS + Y CNPG + L G + C + + + W P P CI +G
Sbjct: 1334 GSTIIYGCNPG------YTLHGSSLLKCMTGERRA--WDYPLPSCIAECGGRFKGESSGR 1385
Query: 248 LVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPD----- 302
++S N + RC + V Q L RV PP+
Sbjct: 1386 ILSPGYPFPYDNNL---RCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLL 1442
Query: 303 --------------VLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSP 348
L+ Q D D FY + G+ ++ ++S+ + P
Sbjct: 1443 KEISGSLIPEGIHSTLNIVTIQFDTD--------FYISKSGFAIQFSSSVATACR---DP 1491
Query: 349 AAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESL 408
P ++ D GR + G V F CD G++L+G C+
Sbjct: 1492 GVPMNGTRNGD--------GR-------EPGDTVVFQCDPGYELQGEERITCIQVENRYF 1536
Query: 409 WNSSVPVCEQIFCPSPPVIP-NGRHTGKPLEV--------FPFGKTVNYTCDPHPDRGTS 459
W S PVC + P G TG + +P + ++T + D S
Sbjct: 1537 WQPSPPVC---------IAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVIS 1587
Query: 460 FDLIGESTIRCTSDPQGNG--VWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGT 517
I S +P + ++ P ++G Q +KL + +S +
Sbjct: 1588 LAFISFSI-----EPNYDFLYIYDGPDSNSPLIGSFQD------SKLPERIESSSNTMHL 1636
Query: 518 SLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRI 577
+ + + Y G F + L R+SC P + +NG + D ++GS +
Sbjct: 1637 AFRSDGSVSYTG--FHLEYKAKL----------RESCFDPGNIMNG-TRLGMDYKLGSTV 1683
Query: 578 NYSCTTGHRLIGHSSAECILSGNAAH-WSTKPPICQRIPCGLPPTIANGDFISTNR-ENF 635
Y C G+ L G+S+ CI+ + W+ P C PCG T + G +S N +N+
Sbjct: 1684 TYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHA-PCGSRSTGSEGTVLSPNYPKNY 1742
Query: 636 HYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVEN 695
G + C K F + G+ + TS D V ++ GP Q + + + +
Sbjct: 1743 SVG----HNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGE 1798
Query: 696 GILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLH 755
+ +S + + F KG V QA+ + CS V +P
Sbjct: 1799 SLPLSSGNQI-----TIRFTSVGPITAKGFHFVY-QAVPRTSST--QCSSVPEP------ 1844
Query: 756 AERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRC----TPQGDWSPAAPTCEVKSCDDF 811
+R + F+ G V + C PGY L G+ ++RC W+ + PTC + C
Sbjct: 1845 -RFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC-IVPCGGI 1902
Query: 812 M----GQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESL--------- 858
+ G +L+ P + L EG ++ S+ +SL
Sbjct: 1903 LTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNN 1962
Query: 859 --------------------------WNSSVPVCEQIF-----------CPSPPVIPNGR 881
+ S + V F CP P +G
Sbjct: 1963 APRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGI 2022
Query: 882 HTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC---- 937
G + + G V++ CD + L G S I C P W+ P P C
Sbjct: 2023 KIG---DRYMVGDVVSFQCDQ------GYSLQGHSHITCMPGPVRR--WNYPIPICLAQC 2071
Query: 938 --------GILGHCQAPD--------------------HFLFAKLKTQT-------NASD 962
G++ P H F T+T +
Sbjct: 2072 GGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGS 2131
Query: 963 FPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKR-----------KSCKTPPDPV 1011
T + P+ FS T +L + S K+ +SC P
Sbjct: 2132 SETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFR 2191
Query: 1012 NGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPT 1071
NG V + D VG I++ C G+ LIG+S+ C L G + +W+ P C+ + CG T
Sbjct: 2192 NGFV-IGNDFTVGQTISFECFPGYTLIGNSALTC-LHGVSRNWNHPLPRCEAL-CGGNIT 2248
Query: 1072 IANGDFISTNRENFHYGSVVTYRCNLGSRGRKV---FELVGEPSIYCTSNDDQVGIWSGP 1128
NG S + + + G + F ++ IY D + +W GP
Sbjct: 2249 AMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIY-----DFITVWDGP 2303
Query: 1129 APQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 1188
P + + S++S + + + F G + A
Sbjct: 2304 DQNS--------PQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQL--- 2352
Query: 1189 ELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTP----QG 1244
RVCQPPP + + E + D F G + Y C PG+ L G A L C Q
Sbjct: 2353 ------RVCQPPPPVPNAEIL-TEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQM 2405
Query: 1245 DWSPEAPRCAVKSCDDFLGQLPHGRVLFP------LNLQLGAKVSFVCDEGFRLK----- 1293
D +P P C V + L G +L P NLQ+ A S ++G+ +
Sbjct: 2406 DGAP--PVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAW-SISVEKGYNITMFVEF 2462
Query: 1294 --------------GSSVSHCVLVGMRSLWNNSVPVCEH--------------------- 1318
G ++ VL+ + ++++ + +
Sbjct: 2463 FQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRI 2522
Query: 1319 ----IFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDP 1374
+C P + +G G + + + CD RG F L+G+S+ C
Sbjct: 2523 RYIAFYCSTPESPPHGYIISQTGGQL--NSVVRWACD----RG--FRLVGKSSAVCRKSS 2574
Query: 1375 HGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGY---F 1431
+G W +P P C+ ++ G K P + ++ VGT + Y C GY
Sbjct: 2575 YGYHAWDAPVPACQ-AISCGIPKAPTNGGILTT-------DYLVGTRVTYFCNDGYRLSS 2626
Query: 1432 GKMFSISCLENLVWSSVEDN--CRRKSCGPPPEPF---NGMVHI--NTDTQFGSTVNYSC 1484
++ + C + WS+ C +C P F +G I + ++ + V +SC
Sbjct: 2627 KELTTAVCQSDGTWSNHNKTPRCVVVTC-PSINSFILEHGRWRIVNGSHYEYKTKVVFSC 2685
Query: 1485 NEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVV 1544
+ G+ +G S CL +G +W + P C+IISC PT NG+ +TS+ G+
Sbjct: 2686 DPGYHGLGPASIECLPNGT-WSWRNERPYCQIISCGELPTPPNGNKIGT-QTSY--GSTA 2741
Query: 1545 TYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPG 1604
+ C G F LVG C S G+WS RC++ + C PE+ +V G
Sbjct: 2742 IFTCDLG------FMLVGSAVRECLSS----GLWSESETRCLAGH-CGIPELIVNGQVIG 2790
Query: 1605 NRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPPPEILHGEHTL 1663
+ + + ++C PGF ++GS CQ + W +LP C V C P ++G
Sbjct: 2791 EN--YGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGR--- 2845
Query: 1664 SHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDD--------FL 1715
+ + F+ V +SC Y ++G C WS P C V +C D
Sbjct: 2846 TSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRE 2905
Query: 1716 GQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCP 1775
++ HG N G V + C+ G+ L G S C G W+ +P C I C
Sbjct: 2906 SKIEHG------NFTYGTVVFYDCNPGYFLFGSSVLICQPNGQ---WDKPLPECIMIDCG 2956
Query: 1776 NPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSS 1835
+P N +G + +G + Y+C +L+G+SS C Q NG WS
Sbjct: 2957 HPGVPPNAVLSGEKY---TFGSTVHYSCTGKR------SLLGQSSRTC----QLNGHWSG 3003
Query: 1836 PAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQG 1895
P C C P +G S + T+ Y CD GY+L G C G
Sbjct: 3004 SQPHCSGDATGTCGDPGTPGHG---SRQESNFRTKSTVRYACDTGYILHGSEERTCLANG 3060
Query: 1896 IWSQLDHYCKEVNCSFPLFMNGISKELEMKKV--YHYGDYVTLKCEDGYTLEGSPWSQCQ 1953
W+ CK V C P G + ++ ++ + V C +GY L G QC
Sbjct: 3061 SWTGRQPECKAVQCGNP----GTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCT 3116
Query: 1954 ADDRWDPPLAKCT 1966
A+ W L CT
Sbjct: 3117 ANGTWSGTLPNCT 3129
Score = 272 bits (695), Expect = 3e-72
Identities = 266/1003 (26%), Positives = 398/1003 (39%), Gaps = 129/1003 (12%)
Query: 43 CNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYS--GRPFSIICLKNS----VWTGAK 96
C+ PE P + T + + + + C G+ G+ S +C K+S W
Sbjct: 2529 CSTPESPPHGYIISQTGG---QLNSVVRWACDRGFRLVGKS-SAVCRKSSYGYHAWDAPV 2584
Query: 97 DRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWD- 155
C+ SC P P NG + + G+++ Y C GYRL T + D W
Sbjct: 2585 PACQAISCGIPKAPTNGGI-LTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGT-WSN 2642
Query: 156 -NETPICDRIPCGLPPTIT-----NGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVG 209
N+TP C + C P+I +G + N ++ Y + V + C+PG G +G
Sbjct: 2643 HNKTPRCVVVTC---PSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHG------LG 2693
Query: 210 EPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPG 269
SI C N W P C I + P NG + S S F C G
Sbjct: 2694 PASIECLPNG--TWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGS---TAIFTCDLG 2748
Query: 270 FVMKGPRRVKCQALNKW-EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEP 328
F++ G +C + W E E + C P +++ Q +N+ V Y C P
Sbjct: 2749 FMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNG---QVIGENYGYRDTVVYQCNP 2805
Query: 329 GYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDE 388
G+ L G++ C +WS P+C SC G + GR V F C+
Sbjct: 2806 GFRLIGSSVRICQQDHNWSGQLPSCVPVSC-GHPGSPIYGRT-SGNGFNFNDVVTFSCNI 2863
Query: 389 GFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGK-PLEVFPFGKTVN 447
G+ ++G + + C W+ P+C+ + C P + N + K F +G V
Sbjct: 2864 GYLMQGPTKAQC---QANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVF 2920
Query: 448 YTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGIL--GHCQAPDHFLFAKLK 505
Y C+P + L G S + C Q NG W P P C ++ GH P + + + K
Sbjct: 2921 YDCNP------GYFLFGSSVLIC----QPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEK 2970
Query: 506 TQTNASDFPIGTSLKYEC--RPEYYGRPFSITCLDNLVWSSPKDVCK---RKSCKTPPDP 560
+ G+++ Y C + G+ S TC N WS + C +C P P
Sbjct: 2971 -------YTFGSTVHYSCTGKRSLLGQS-SRTCQLNGHWSGSQPHCSGDATGTCGDPGTP 3022
Query: 561 VNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPP 620
+G ++ + S + Y+C TG+ L G C+ +G+ W+ + P C+ + CG P
Sbjct: 3023 GHGS-RQESNFRTKSTVRYACDTGYILHGSEERTCLANGS---WTGRQPECKAVQCGNPG 3078
Query: 621 TIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 680
T ANG + F S V Y C G + L G CT+N G WSG P
Sbjct: 3079 TTANGKVFRIDGTTF--SSSVIYSCMEG------YILSGPSVRQCTAN----GTWSGTLP 3126
Query: 681 QCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMK--GPRRVKCQALNKWEP 738
C I + P NG+ D+ + + + V + CQPG+ M+ G R C W
Sbjct: 3127 NCTIISCGDPGIPANGLRYGDD---YVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSG 3183
Query: 739 ELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWS 797
+P+C V C PP + + + + NF G + Y C PGY+L A + C G WS
Sbjct: 3184 VMPTCRAVTCPTPPQISNG---RLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWS 3240
Query: 798 PAAPTCEVKSCDD----FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLA 853
P C K C D G+ ++ ++V F C+ F L GSS C
Sbjct: 3241 GEVPQCLPKFCGDPGIPAQGKREGKSFIYQ------SEVSFSCNFPFILVGSSTRICQAD 3294
Query: 854 GMESLWNSSVPVC---EQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSF 910
G W+ S P C Q C +P V +G FG V H +G
Sbjct: 3295 G---TWSGSSPHCIEPTQTSCENPGVPRHGSQNN------TFGFQVGSVVQFHCKKGHL- 3344
Query: 911 DLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPI-GTSL 969
L G +T C D WS P C I C+ P+ A + D P G +L
Sbjct: 3345 -LQGSTTRTCLPDL----TWSGIQPEC-IPHSCKQPETPAHANVV----GMDLPSHGYTL 3394
Query: 970 KYECRPEYY--GRPFSITCLDNLVWSSPKDVCKRKSCKTPPDP 1010
Y C+P ++ G C + W+ +C+ S DP
Sbjct: 3395 IYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDP 3437
Score = 80.1 bits (196), Expect = 2e-14
Identities = 93/409 (22%), Positives = 153/409 (37%), Gaps = 99/409 (24%)
Query: 1457 CGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCL-VSGNNVTWDKKAPICE 1515
C P EP NG I +D GSTV +SC+E + L G+ S TC ++ W P+C+
Sbjct: 446 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 504
Query: 1516 IISCE-----PPPTISNGDF---YSNNR------TSFHNGTVVT-----------YQCHT 1550
+ +C P T ++ +F Y +N T+ + V+ Y T
Sbjct: 505 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 564
Query: 1551 GPDGEQLFELVGERSIYCTS-KDDQVGVWSSPPPRCISTN--------KCTAPEVEN-AI 1600
DG ++ + + S D + SS + T+ K E+E +
Sbjct: 565 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 624
Query: 1601 RVPGNRSF-------FTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHC-----SR 1648
PG + F+ +++RF CQ GF ++G ++ CQ N +W +P C S
Sbjct: 625 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSN 684
Query: 1649 VCQPPPEILHGEHTLSHQDNFS--------PGQEVFYSCEPSYDLRGAASLHCTPQGDWS 1700
P +L ++ + +N + PG + S +DL GD S
Sbjct: 685 FTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDGD-S 742
Query: 1701 PEAPRCTVKSCDDFLGQLPHGRVLLPL--------------------------------- 1727
PE+P + + L +L L
Sbjct: 743 PESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPIN 802
Query: 1728 ------NLQLGAKVSFVCDEGF-RLKGRSASHCVLAGMKALWNSSVPVC 1769
N QLG+ +S +C+EGF + +G C+L K +W+ +P C
Sbjct: 803 ARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 851
Score = 69.7 bits (169), Expect = 3e-11
Identities = 134/603 (22%), Positives = 207/603 (34%), Gaps = 149/603 (24%)
Query: 1156 FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC-----SRVCQPPPEILHGEHTP 1210
FS +V+ F CQ GF + G + + CQ N+W +P C S P +L ++
Sbjct: 640 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPE 699
Query: 1211 SHQDNFS--------PGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAP----------- 1251
+ +N + PG + S +DL GD SPE+P
Sbjct: 700 GYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDGD-SPESPILGTFTGAEVP 757
Query: 1252 ----------RCAVKSCDDFLGQ------------------LPHGRVLFPLNLQLGAKVS 1283
R ++ G+ +P F N QLG+ +S
Sbjct: 758 SHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSIS 817
Query: 1284 FVCDEGF-RLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDI-- 1340
+C+EGF + +G+ C+L+ + +W+ +P C P G H PSG I
Sbjct: 818 VICEEGFIKTQGTETITCILMDGKVMWSGLIPKC------GAPC---GGHFSAPSGVILS 868
Query: 1341 ---PYGKEISYTC------DPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSV 1391
P + S C +P +TF + H SP L
Sbjct: 869 PGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSP-----LLG 923
Query: 1392 RAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDN 1451
+ P QF F+S ++F + + T+ N G+ + + SV N
Sbjct: 924 SYNGTQVP-QFLFSS-----SNFIYLLFTTDNSRSNNGF-----------KIHYESVTVN 966
Query: 1452 CRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKA 1511
SC P P +G D GSTV++SC+ G+RL C N W
Sbjct: 967 --TYSCLDPGIPVHGR-RYGHDFSIGSTVSFSCDSGYRLSHEEPLLC---EKNHWWSHPL 1020
Query: 1512 PICEIIS----CEPPPTISN---GDFYSNN-----RTSFHNGTVVTYQCHT-GPDGEQLF 1558
P C+ + P TI + +FY N+ +G V + HT + +
Sbjct: 1021 PTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDY 1080
Query: 1559 ELVGERSIYCTSKDDQVGVWSSPPP--------------RCISTNKCT------------ 1592
L+ E + G S PP R IS +
Sbjct: 1081 LLITENGSFTQPLARLTG--SDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1138
Query: 1593 -APEVENAIRVPGNRSFFT--LTEIIRFRCQPGFVMVGSHTVQCQTNGR--WGPKLPHCS 1647
P + I G+R F + + + F C G+ + G+ + C GR W LP C
Sbjct: 1139 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1198
Query: 1648 RVC 1650
C
Sbjct: 1199 AEC 1201
Score = 69.3 bits (168), Expect = 4e-11
Identities = 134/623 (21%), Positives = 213/623 (34%), Gaps = 134/623 (21%)
Query: 706 FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC-----QPPPDVLHAERTQ 760
FS +V+ F CQ GF + G + + CQ N+W +P C C P VL + +
Sbjct: 640 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPE 699
Query: 761 RDKDNFS--------PGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM 812
+N + PG + S +DL GD SP +P + +
Sbjct: 700 GYGNNLNCIWTIISDPGSRIHLSFND-FDLESQFDFLAVKDGD-SPESPILGTFTGAEVP 757
Query: 813 GQLL-NGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFC 871
L N +L +++F D +G + +Y E C
Sbjct: 758 SHLTSNSHIL---------RLEFQADHSMSGRGFNITYNTFGHNE--------------C 794
Query: 872 PSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 931
P P + N R G + F G +++ C+ G TI C G +WS
Sbjct: 795 PDPGIPINARRFG---DNFQLGSSISVICEEG-----FIKTQGTETITCIL-MDGKVMWS 845
Query: 932 SPAPRCGIL--GHCQA---------------------------PDHFL---FAKLKTQTN 959
P+CG GH A P H + F + +T+ N
Sbjct: 846 GLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN 905
Query: 960 ASDFPI--GTSLKYECRPEYYGRP-----FSITCLDNLVWSSPKD-------------VC 999
+ G +L Y G FS + L++++
Sbjct: 906 YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTV 965
Query: 1000 KRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPP 1059
SC P PV+G + D +GS +++SC +G+RL S E +L WS P
Sbjct: 966 NTYSCLDPGIPVHGRRYG-HDFSIGSTVSFSCDSGYRL---SHEEPLLCEKNHWWSHPLP 1021
Query: 1060 ICQRIPCGLPPTIANGDFISTNRENFHYGSV-VTYRCNLGSRGRKVFELVGEPSIYCTSN 1118
C + CG +G +S F+ S+ T+ ++ + G+ V + + +
Sbjct: 1022 TCDAL-CGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDV-THGKGV--QFNFHTFHLEDH 1077
Query: 1119 DDQVGI---WSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP 1175
D + I S P + PP + G+ + FR Q F+
Sbjct: 1078 HDYLLITENGSFTQPLARLTGSDLPPTINAGLYGN-------------FRAQLRFI--SD 1122
Query: 1176 RRVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGA 1235
+ + N E C+ P +G NF G + +SC GY L G
Sbjct: 1123 FSISYEGFNITFSEYN--LEPCEDPGIPQYGSRIGF---NFGIGDTLTFSCSSGYRLEGT 1177
Query: 1236 ASLHCTPQGD--WSPEAPRCAVK 1256
+ + C G WS PRC +
Sbjct: 1178 SEIICLGGGRRVWSAPLPRCVAE 1200
Score = 65.9 bits (159), Expect = 4e-10
Identities = 203/866 (23%), Positives = 304/866 (35%), Gaps = 179/866 (20%)
Query: 910 FDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSL 969
F+LIGE +I C Q N WS+ P C +F L T P+GT L
Sbjct: 654 FELIGEKSIVC----QENNQWSANIPIC------------IFPCLSNFTA----PMGTVL 693
Query: 970 KYECRPEYYGRPFSITCLDNLV---------------WSSPKDVCKRKSCKTPPDPVNGM 1014
+ PE YG ++ C+ ++ S D K +P P+ G
Sbjct: 694 SPDY-PEGYGN--NLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILG- 749
Query: 1015 VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPC-GLPPTIA 1073
T +V S + + H L A+ +SG + + P G+P
Sbjct: 750 --TFTGAEVPSHLT---SNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIP---- 800
Query: 1074 NGDFISTNR--ENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 1131
I+ R +NF GS ++ C G + G +I C D +V +WSG P+
Sbjct: 801 ----INARRFGDNFQLGSSISVICEEG-----FIKTQGTETITCILMDGKV-MWSGLIPK 850
Query: 1132 CIIPNKCTPP-NVENGILVSDNRSLF---SLNEVVEFRCQPGFVMKGPRRVKCQALNKWE 1187
C P C + +G+++S + SLN +PG +K LN
Sbjct: 851 CGAP--CGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDV 908
Query: 1188 PELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWS 1247
E+ + P +G P + S + ++ + G +H
Sbjct: 909 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGF-KIHY------- 960
Query: 1248 PEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRS 1307
E+ SC D G HGR + + +G+ VSF CD G+RL S +L
Sbjct: 961 -ESVTVNTYSCLD-PGIPVHGR-RYGHDFSIGSTVSFSCDSGYRL---SHEEPLLCEKNH 1014
Query: 1308 LWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDI---------PYGKEISYTCDPHPDRGM 1358
W++ +P C+ A+ G G PSG I P ++T D +G+
Sbjct: 1015 WWSHPLPTCD--------ALCGGDVRG-PSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV 1065
Query: 1359 TFNLIGESTIRCTSDPHG------NGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPIN 1412
FN T D H NG ++ P R S F + I+
Sbjct: 1066 QFNF---HTFHL-EDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFIS 1121
Query: 1413 DFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINT 1472
DF S++YE F FS LE C P P G I
Sbjct: 1122 DF------SISYEG----FNITFSEYNLE--------------PCEDPGIPQYGS-RIGF 1156
Query: 1473 DTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYS 1532
+ G T+ +SC+ G+RL G+ CL G V W P C + C T + G S
Sbjct: 1157 NFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRV-WSAPLPRC-VAECGASATNNEGILLS 1214
Query: 1533 -NNRTSFHNGTVVTY--QCHTGPD---GEQLFELV-GERSIYCTSKDDQ---VGVWSSPP 1582
N ++ N Y Q G + F L G+ KD +G ++
Sbjct: 1215 PNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGAS 1274
Query: 1583 PRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPK 1642
R + T N + + N E GF +V + +
Sbjct: 1275 MRGL-----TLSSTSNQLWLEFNSDTEGTDE--------GFQLVYTSF-----------E 1310
Query: 1643 LPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCT--PQGDWS 1700
L HC P I + +S Q +F+ G + Y C P Y L G++ L C + W
Sbjct: 1311 LSHCE-----DPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSSLLKCMTGERRAWD 1364
Query: 1701 PEAPRCTVKSCDDFLGQLPHGRVLLP 1726
P C + F G+ GR+L P
Sbjct: 1365 YPLPSCIAECGGRFKGE-SSGRILSP 1389
Score = 65.1 bits (157), Expect = 7e-10
Identities = 152/670 (22%), Positives = 244/670 (36%), Gaps = 117/670 (17%)
Query: 183 ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP- 241
+NF GS ++ C G + G +I C D +V +WSG P+C P C
Sbjct: 808 DNFQLGSSISVICEEG-----FIKTQGTETITCILMDGKV-MWSGLIPKCGAP--CGGHF 859
Query: 242 NVENGILVSDNRSLF---SLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQ 298
+ +G+++S + SLN +PG +K +++ EL
Sbjct: 860 SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIK-------ITFERFQTELNYDVLEVH 912
Query: 299 PPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSC 358
P++L + Q +F S Y L + R + T SC
Sbjct: 913 DGPNLLSP--LLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSC 970
Query: 359 DDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQ 418
D G ++GR + + +G+ V F CD G++L C W+ +P C+
Sbjct: 971 LD-PGIPVHGR-RYGHDFSIGSTVSFSCDSGYRLSHEEPLLCE---KNHWWSHPLPTCDA 1025
Query: 419 IFCPSPPVIPNGR--HTGKPLEVFPFGKTVNYTCDPHPDRGTSFD-------------LI 463
+ C P+G G P E +P +T D +G F+ LI
Sbjct: 1026 L-CGGDVRGPSGTILSPGYP-EFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLI 1083
Query: 464 GESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYEC 523
E+ + G P G+ G+ +A F+ SDF S+ YE
Sbjct: 1084 TENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFI----------SDF----SISYE- 1128
Query: 524 RPEYYGRPFSITCLD-NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCT 582
F+IT + NL + C+ P P G + + +G + +SC+
Sbjct: 1129 -------GFNITFSEYNL-----------EPCEDPGIPQYGS-RIGFNFGIGDTLTFSCS 1169
Query: 583 TGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNR----ENFHYG 638
+G+RL G S C L G WS P C CG T G +S N EN H
Sbjct: 1170 SGYRLEGTSEIIC-LGGGRRVWSAPLPRCVA-ECGASATNNEGILLSPNYPLNYENNHE- 1226
Query: 639 SVVTYRCNPGSG---GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVEN 695
+ + + G G + F L + D + I+ G + T ++
Sbjct: 1227 CIYSIQVQAGKGINISARTFHL---------AQGDVLKIYDGKDKTTHLLGAFTGASMRG 1277
Query: 696 GILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLH 755
L S + L+ +EF +G + V EL C P +
Sbjct: 1278 LTLSSTSNQLW-----LEFNSDTEGTDEGFQLVYTSF------ELSHCE-----DPGIPQ 1321
Query: 756 AERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT--PQGDWSPAAPTCEVKSCDDFMG 813
D+ +F+ G + Y C PGY L G++ ++C + W P+C + F G
Sbjct: 1322 FGYKISDQGHFA-GSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKG 1380
Query: 814 QLLNGRVLFP 823
+ +GR+L P
Sbjct: 1381 E-SSGRILSP 1389
Score = 63.9 bits (154), Expect = 2e-09
Identities = 107/455 (23%), Positives = 163/455 (35%), Gaps = 100/455 (21%)
Query: 104 CRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCI-ISGDTVIWDNETPICD 162
C +P +P NG + GS +++SC + Y L G+ S TC I+ W + P+C
Sbjct: 446 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 504
Query: 163 RIPC-----GLPPTITNGDF----------------ISTNRE---NFH-YGSVVTY-RCN 196
C G T T+ +F ++TN+ NF + + Y
Sbjct: 505 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 564
Query: 197 PGSGG-----RKVFE-LVGE--PSIYCTSN---------DDQVG-IWSGPAPQCIIPNKC 238
G GG R V + L G P + + + D+ VG + + I C
Sbjct: 565 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 624
Query: 239 TPPNVE-NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC---- 293
P GI D FS +V+ F CQ GF + G + + CQ N+W +P C
Sbjct: 625 GDPGTPLYGIREGDG---FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPC 681
Query: 294 -SRVCQPPPDVLHAERTQRDKDNFS--------PGQEVFYSCEPGYDLRGAASMRCTPQG 344
S P VL + + +N + PG + S +DL G
Sbjct: 682 LSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDG 740
Query: 345 DWSPAAPTCEVKSCDDFMGQLL-NGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLA 403
D SP +P + + L N +L +++F D +G + +Y
Sbjct: 741 D-SPESPILGTFTGAEVPSHLTSNSHIL---------RLEFQADHSMSGRGFNITYNTFG 790
Query: 404 GMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLI 463
E CP P + N R G + F G +++ C+
Sbjct: 791 HNE--------------CPDPGIPINARRFG---DNFQLGSSISVICEE-----GFIKTQ 828
Query: 464 GESTIRCTSDPQGNGVWSSPAPRCGIL--GHCQAP 496
G TI C G +WS P+CG GH AP
Sbjct: 829 GTETITCIL-MDGKVMWSGLIPKCGAPCGGHFSAP 862
Score = 60.8 bits (146), Expect = 1e-08
Identities = 136/619 (21%), Positives = 200/619 (32%), Gaps = 134/619 (21%)
Query: 384 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIF-CPSPPVIPNGRHTGKPLEVFPF 442
F C GF+L G + C + W++++P+C IF C S P G +P
Sbjct: 648 FECQFGFELIGEKSIVCQ---ENNQWSANIPIC--IFPCLSNFTAPMGTVLSPD---YPE 699
Query: 443 GKTVNYTC------DPHPDRGTSF-DLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQA 495
G N C DP SF D ES + G+ S +P G +
Sbjct: 700 GYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD---SPESPILGTFTGAEV 756
Query: 496 PDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCK 555
P H T+ S L+++ GR F+IT + C
Sbjct: 757 PSHL--------TSNSHI---LRLEFQADHSMSGRGFNITY----------NTFGHNECP 795
Query: 556 TPPDPVNGMVHVITDIQVGSRINYSCTTGH-RLIGHSSAECILSGNAAHWSTKPPICQRI 614
P P+N + Q+GS I+ C G + G + CIL WS P C
Sbjct: 796 DPGIPINAR-RFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGA- 853
Query: 615 PCGLPPTIANGDFISTNRENFHYGSVV---TYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
PCG + +G +S ++ S+ PG + FE N D
Sbjct: 854 PCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFE-----RFQTELNYDV 908
Query: 672 VGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ 731
+ + GP + V L S + ++ L R GF + +
Sbjct: 909 LEVHDGPNLLSPLLGSYNGTQVPQ-FLFSSSNFIYLLFTTDNSRSNNGFKI----HYESV 963
Query: 732 ALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 791
+N + C P +H R D FS G V +SC+ GY L + C
Sbjct: 964 TVNTYS---------CLDPGIPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCE 1011
Query: 792 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVL-------FPVNLQLGAKVDFVCDEGFQ--- 841
WS PTC+ D G +G +L +P +L VD +G Q
Sbjct: 1012 KNHWWSHPLPTCDALCGGDVRGP--SGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNF 1069
Query: 842 --------------------------LKGSSASYCVLAGMESLWNSSVPVCEQIF----- 870
L GS + AG+ + + +
Sbjct: 1070 HTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEG 1129
Query: 871 ------------CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTI 918
C P + G G F G + ++C + + L G S I
Sbjct: 1130 FNITFSEYNLEPCEDPGIPQYGSRIGFN---FGIGDTLTFSC------SSGYRLEGTSEI 1180
Query: 919 RCTSDPQGNGVWSSPAPRC 937
C G VWS+P PRC
Sbjct: 1181 ICLGG--GRRVWSAPLPRC 1197
Score = 60.5 bits (145), Expect = 2e-08
Identities = 142/626 (22%), Positives = 212/626 (33%), Gaps = 125/626 (19%)
Query: 553 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL-SGNAAHWSTKPPIC 611
SC P P G+++ T VG +I YSC TG+ L GH CI S N A W PIC
Sbjct: 137 SCGNPGVPPKGVLYG-TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 195
Query: 612 Q-RIPCGLPPTIANGDFISTNREN-FHYGSVVTYR--CNPGSGGRKVFELVGEPSIYCTS 667
+ CG ++G S + N +H + T+ PG +F
Sbjct: 196 RAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIF-----TDFQMEE 250
Query: 668 NDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVE-------FRCQPGF 720
D + I P + PP + N++ L+ V + F
Sbjct: 251 KYDYLEIEGSEPPTIWLSGMNIPPP------IISNKNWLRLHFVTDSNHRYRGFSAPYQG 304
Query: 721 VMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY 780
L + V P DV + T S Q V +
Sbjct: 305 SSTLTHTTSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVT----- 359
Query: 781 DLRGAASMRCTPQGDWSP-AAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEG 839
LR + T + SP A T + Q+ + L V ++ +DF G
Sbjct: 360 SLRNSGLDPNTSKDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFK-SRG 418
Query: 840 FQL---KGSSASYCVL--AGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGK 894
F+L K +S + +L G+++ N CP P NG+ G F G
Sbjct: 419 FKLFPGKDNSNKFSILNEGGIKTASN---------LCPDPGEPENGKRIGSD---FSLGS 466
Query: 895 AVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGIL---GHCQAPDHFLF 951
V ++CD + L G +I C + WS P C + + Q P
Sbjct: 467 TVQFSCD------EDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFT 520
Query: 952 A---KLKTQTNASDFPIGTSLKYECRPEYYGRPF-------SITCLDNLVWSSPKDVCKR 1001
+ + +NA + T++ + F ++T D P+ V +
Sbjct: 521 SPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQV 580
Query: 1002 KSCKTPPDPVNGM-----VHVITDIQVGS---RINYSCTTGHRLIGHSSAECILSGNTAH 1053
+ PD + M +H+ TD VGS ++NY
Sbjct: 581 LTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYK----------------------- 617
Query: 1054 WSTKPPICQRIPCGLPPT----IANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVG 1109
++ CG P T I GD S NR+ V+ + C G FEL+G
Sbjct: 618 ------EIEKESCGDPGTPLYGIREGDGFS-NRD------VLRFECQFG------FELIG 658
Query: 1110 EPSIYCTSNDDQVGIWSGPAPQCIIP 1135
E SI C N+ WS P CI P
Sbjct: 659 EKSIVCQENNQ----WSANIPICIFP 680
Score = 60.1 bits (144), Expect = 2e-08
Identities = 104/479 (21%), Positives = 156/479 (32%), Gaps = 110/479 (22%)
Query: 69 LNYECRPGYSGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIK 128
L ++ SGR F+I + C +P P+N Q GS I
Sbjct: 769 LEFQADHSMSGRGFNI----------TYNTFGHNECPDPGIPINAR-RFGDNFQLGSSIS 817
Query: 129 YSCTKGY-RLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHY 187
C +G+ + G+ + TCI+ V+W P C PCG + +G +S ++
Sbjct: 818 VICEEGFIKTQGTETITCILMDGKVMWSGLIPKCG-APCGGHFSAPSGVILSPGWPGYYK 876
Query: 188 GSV---VTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGP---APQCIIPNKCTPP 241
S+ PG + FE N D + + GP +P N P
Sbjct: 877 DSLNCEWVIEAEPGHSIKITFE-----RFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVP 931
Query: 242 NVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPP 301
L S + ++ L R GF + + +N + C P
Sbjct: 932 Q----FLFSSSNFIYLLFTTDNSRSNNGFKI----HYESVTVNTYS---------CLDPG 974
Query: 302 DVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF 361
+H R D FS G V +SC+ GY L + C WS PTC+ D
Sbjct: 975 IPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDV 1031
Query: 362 MGQLLNGRVL-------FPVNLQLGAKVDFVCDEGFQ----------------------- 391
G +G +L +P +L VD +G Q
Sbjct: 1032 RGP--SGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSF 1089
Query: 392 ------LKGSSASYCVLAGMESLWNSSVPVCEQIF-----------------CPSPPVIP 428
L GS + AG+ + + + C P +
Sbjct: 1090 TQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQ 1149
Query: 429 NGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 487
G G F G T+ ++C + + L G S I C G VWS+P PRC
Sbjct: 1150 YGSRIGFN---FGIGDTLTFSC------SSGYRLEGTSEIICLGG--GRRVWSAPLPRC 1197
Score = 59.7 bits (143), Expect = 3e-08
Identities = 139/652 (21%), Positives = 216/652 (33%), Gaps = 142/652 (21%)
Query: 104 CRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 163
C +P P G + G + +SC+ GYRL G+S C + G +W P C
Sbjct: 1142 CEDPGIPQYGS-RIGFNFGIGDTLTFSCSSGYRLEGTSEIIC-LGGGRRVWSAPLPRC-V 1198
Query: 164 IPCGLPPTITNGDFIS----TNRENFHYGSVVTYRCNPGSG---GRKVFELVGEPSIYCT 216
CG T G +S N EN H + + + G G + F L
Sbjct: 1199 AECGASATNNEGILLSPNYPLNYENNH-ECIYSIQVQAGKGINISARTFHL--------- 1248
Query: 217 SNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 276
+ D + I+ G + T ++ L S + L+ +EF +G +
Sbjct: 1249 AQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLW-----LEFNSDTEGTDEGFQ 1303
Query: 277 RVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAA 336
V EL C P + D+ +F+ G + Y C PGY L G++
Sbjct: 1304 LVYTSF------ELSHCE-----DPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSS 1351
Query: 337 SMRCT--PQGDWSPAAPTCEVKSCDDFMGQLLNGRVL-----FPVNLQLGAKVDFVCDEG 389
++C + W P+C + F G+ +GR+L FP + L D G
Sbjct: 1352 LLKCMTGERRAWDYPLPSCIAECGGRFKGE-SSGRILSPGYPFPYDNNLRCMWMIEVDPG 1410
Query: 390 ------FQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPF- 442
F + AS+ +L +W+ + S +IP G H+ + F
Sbjct: 1411 NIVSLQFLAFDTEASHDIL----RVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFD 1466
Query: 443 ----------------------------------------GKTVNYTCDPHPDRGTSFDL 462
G TV + CDP ++L
Sbjct: 1467 TDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDP------GYEL 1520
Query: 463 IGESTIRCTSDPQGNGVWSSPAPRC---------GILGHCQAPDHFLFAKLKTQTNASDF 513
GE I C + W P C G G +P+ F + D+
Sbjct: 1521 QGEERITCI-QVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPN---FPHPYPHSRDCDW 1576
Query: 514 PIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQV 573
I + Y + FSI + ++ PD + ++ D ++
Sbjct: 1577 TITVNADYVISLAFIS--FSIEPNYDFLY-----------IYDGPDSNSPLIGSFQDSKL 1623
Query: 574 GSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRE 633
RI S T H L S +G + K R C P I NG +
Sbjct: 1624 PERIESSSNTMH-LAFRSDGSVSYTGFHLEYKAK----LRESCFDPGNIMNGTRLGM--- 1675
Query: 634 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIP 685
++ GS VTY C+ G + L G ++ C DD W+ P C P
Sbjct: 1676 DYKLGSTVTYYCDAG------YVLQGYSTLTCIMGDDGRPGWNRALPSCHAP 1721
Score = 49.3 bits (116), Expect = 4e-05
Identities = 70/277 (25%), Positives = 98/277 (35%), Gaps = 34/277 (12%)
Query: 1004 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNT-AHWSTKPPICQ 1062
C P +P NG + +D +GS + +SC + L G S C A WS P+C+
Sbjct: 446 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 504
Query: 1063 RIPCGLPPTIANGDFISTNRENFHYGS------VVTYRCNLGSRGRKVFELVGEPSIYCT 1116
CG +G F S N F Y S V+T N + FE Y T
Sbjct: 505 VKTCGSNLQGPSGTFTSPNFP-FQYDSNAQCVWVIT-AVNTNKVIQINFEEFDLEIGYDT 562
Query: 1117 SNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 1176
G P + P+ ++VS + ++ + E GF
Sbjct: 563 LTIGDGGEVGDPRTVLQVLTGSFVPD----LIVSMSSQMWLHLQTDESVGSVGF------ 612
Query: 1177 RVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAA 1236
+N E E SC P I G D FS + + C+ G++L G
Sbjct: 613 -----KVNYKEIEKESCGDPGTPLYGIREG-------DGFSNRDVLRFECQFGFELIGEK 660
Query: 1237 SLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFP 1273
S+ C WS P C +F P G VL P
Sbjct: 661 SIVCQENNQWSANIPICIFPCLSNFTA--PMGTVLSP 695
Score = 48.1 bits (113), Expect = 9e-05
Identities = 140/645 (21%), Positives = 212/645 (32%), Gaps = 136/645 (21%)
Query: 1360 FNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVG 1419
F LIGE +I C N WS+ P C FP S +F P+G
Sbjct: 654 FELIGEKSIVCQE----NNQWSANIPICI-------------FPCLS------NFTAPMG 690
Query: 1420 TSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRR-------------------KSCGPP 1460
T L+ + GY + N +W+ + D R K P
Sbjct: 691 TVLSPDYPEGYGNNL-------NCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSP 743
Query: 1461 PEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCE 1520
P G T + S + S + RL + G N+T++ C
Sbjct: 744 ESPILGTF---TGAEVPSHLT-SNSHILRLEFQADHSMSGRGFNITYNTFGHN----ECP 795
Query: 1521 PPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSS 1580
P N + +N F G+ ++ C G + G +I C D +V +WS
Sbjct: 796 DPGIPINARRFGDN---FQLGSSISVICEEG-----FIKTQGTETITCILMDGKV-MWSG 846
Query: 1581 PPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWG 1640
P+C + I PG ++ + C+ H+++ T R+
Sbjct: 847 LIPKCGAPCGGHFSAPSGVILSPGWPGYYKDS----LNCEWVIEAEPGHSIKI-TFERFQ 901
Query: 1641 PKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWS 1700
+L + P +L L + Q +F S Y L +
Sbjct: 902 TELNYDVLEVHDGPNLL--SPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIH 959
Query: 1701 PEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKA 1760
E+ SC D G HGR + +G+ VSF CD G+RL S +L
Sbjct: 960 YESVTVNTYSCLD-PGIPVHGR-RYGHDFSIGSTVSFSCDSGYRL---SHEEPLLCEKNH 1014
Query: 1761 LWNSSVPVCE------------QIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDT-HP 1807
W+ +P C+ I P P T D+ +GK + + T H
Sbjct: 1015 WWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHL 1074
Query: 1808 DRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSL- 1866
+ + LI E NG ++ P R PP I G Y L
Sbjct: 1075 EDHHDYLLITE-----------NGSFTQPLARL-----TGSDLPPTINAGLYGNFRAQLR 1118
Query: 1867 YLPGMTISYICDPGYLLVGKGFIF--CTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEM 1924
++ +ISY G+ + + C D GI Y + +F +
Sbjct: 1119 FISDFSISY---EGFNITFSEYNLEPCEDPGI----PQYGSRIGFNFGI----------- 1160
Query: 1925 KKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDR--WDPPLAKCTS 1967
GD +T C GY LEG+ C R W PL +C +
Sbjct: 1161 ------GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVA 1199
Score = 47.0 bits (110), Expect = 2e-04
Identities = 68/277 (24%), Positives = 99/277 (35%), Gaps = 34/277 (12%)
Query: 554 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNA-AHWSTKPPICQ 612
C P +P NG + +D +GS + +SC + L G S C A WS P+C+
Sbjct: 446 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 504
Query: 613 RIPCGLPPTIANGDFISTNRENFHYGS------VVTYRCNPGSGGRKVFELVGEPSIYCT 666
CG +G F S N F Y S V+T N + FE Y T
Sbjct: 505 VKTCGSNLQGPSGTFTSPNFP-FQYDSNAQCVWVIT-AVNTNKVIQINFEEFDLEIGYDT 562
Query: 667 SNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 726
G P + P+ ++VS + ++ + E GF
Sbjct: 563 LTIGDGGEVGDPRTVLQVLTGSFVPD----LIVSMSSQMWLHLQTDESVGSVGF------ 612
Query: 727 RVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAA 786
+N E E SC P + R+ D FS + + C+ G++L G
Sbjct: 613 -----KVNYKEIEKESCGDPGTPLYGI-------REGDGFSNRDVLRFECQFGFELIGEK 660
Query: 787 SMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP 823
S+ C WS P C +F + G VL P
Sbjct: 661 SIVCQENNQWSANIPICIFPCLSNFTAPM--GTVLSP 695
Score = 46.6 bits (109), Expect = 2e-04
Identities = 25/66 (37%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 97 DRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCII-SGDTVIWD 155
+ + SC NP P G+++ + G +I+YSC GY L G TCI S +T WD
Sbjct: 131 EELQSSSCGNPGVPPKGVLYGTR-FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWD 189
Query: 156 NETPIC 161
PIC
Sbjct: 190 FPVPIC 195
Score = 46.6 bits (109), Expect = 2e-04
Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
Query: 1450 DNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLV-SGNNVTWD 1508
+ + SCG P P G+++ T G + YSC G+ L G P TC+ S N +WD
Sbjct: 131 EELQSSSCGNPGVPPKGVLY-GTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWD 189
Query: 1509 KKAPIC 1514
PIC
Sbjct: 190 FPVPIC 195
Score = 45.1 bits (105), Expect = 7e-04
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Query: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 162
+CR+P P+NG + G + G + + C GY L G TCI + W P+C
Sbjct: 1487 ACRDPGVPMNGTRNG-DGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC- 1544
Query: 163 RIPCGLPPTITNGDFISTN 181
PCG T ++G +S N
Sbjct: 1545 IAPCGGNLTGSSGFILSPN 1563
Score = 44.3 bits (103), Expect = 0.001
Identities = 83/385 (21%), Positives = 138/385 (35%), Gaps = 90/385 (23%)
Query: 1416 FPVGTSLNYECRPGYFGKMF-SISCLENLV----WSSVEDNCRRK-SCGPPPEPFNGMVH 1469
F VG + Y C GY ++C+ N V W CR + +CG +G++
Sbjct: 154 FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGII- 212
Query: 1470 INTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPP------- 1522
+ F + + + + + ++ P T + + ++K EI EPP
Sbjct: 213 --SSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGM 270
Query: 1523 ----PTISNGDFY-------SNNR-----TSFHNGTVVTYQCHTGPDGEQLFELVGERSI 1566
P ISN ++ SN+R + + +T+ TG E G ++
Sbjct: 271 NIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGELEEHNRTTTGAIAV 330
Query: 1567 YCT-----------------SKDDQVGVWS---------------SPPPRCISTNKCTAP 1594
T S++ +V V S SP P + + T
Sbjct: 331 ASTPADVTVSSVTAVTIHRLSEEQRVQVTSLRNSGLDPNTSKDGLSPHP---ADTQSTRR 387
Query: 1595 EVENAIRVPGNRSFFTLTEIIR---------FRCQPGFVMVGSHTVQCQTNGRWGPKLPH 1645
+A ++ + +T ++ F+ PG S+ G +
Sbjct: 388 RPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPG--KDNSNKFSILNEGG----IKT 441
Query: 1646 CSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGD----WSP 1701
S +C P E +G+ S +FS G V +SC+ Y L+GA S+ C + WS
Sbjct: 442 ASNLCPDPGEPENGKRIGS---DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSD 498
Query: 1702 EAPRCTVKSCDDFLGQLPHGRVLLP 1726
P C VK+C L Q P G P
Sbjct: 499 HRPVCKVKTCGSNL-QGPSGTFTSP 522
Score = 44.3 bits (103), Expect = 0.001
Identities = 31/91 (34%), Positives = 43/91 (47%), Gaps = 8/91 (8%)
Query: 1187 EPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD- 1245
E + + S +C P E +G+ S +FS G V +SC+ Y L+GA S+ C +
Sbjct: 436 EGGIKTASNLCPDPGEPENGKRIGS---DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEV 492
Query: 1246 ---WSPEAPRCAVKSCDDFLGQLPHGRVLFP 1273
WS P C VK+C L Q P G P
Sbjct: 493 FAAWSDHRPVCKVKTCGSNL-QGPSGTFTSP 522
Score = 43.9 bits (102), Expect = 0.002
Identities = 26/76 (34%), Positives = 38/76 (50%), Gaps = 7/76 (9%)
Query: 287 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGD- 345
E + + S +C PD E +R +FS G V +SC+ Y L+GA S+ C +
Sbjct: 436 EGGIKTASNLC---PDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEV 492
Query: 346 ---WSPAAPTCEVKSC 358
WS P C+VK+C
Sbjct: 493 FAAWSDHRPVCKVKTC 508
Score = 38.9 bits (89), Expect = 0.052
Identities = 146/721 (20%), Positives = 228/721 (31%), Gaps = 238/721 (33%)
Query: 101 RKSCRNPPDPVNGMVHVIKGIQFGSQ--IKYSCTKGYRLIGSSSATCIISGDTVIWDNET 158
++SC +P P+ G + +G F ++ +++ C G+ LIG S C + W
Sbjct: 621 KESCGDPGTPLYG---IREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ---WSANI 674
Query: 159 PICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPS--IYCT 216
PIC PC T G +S + Y G+ ++ ++ +P I+ +
Sbjct: 675 PIC-IFPCLSNFTAPMGTVLSPD-----------YPEGYGNNLNCIWTIISDPGSRIHLS 722
Query: 217 SND-------DQVGIWSGPAPQCII----------------------------------- 234
ND D + + G +P+ I
Sbjct: 723 FNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGF 782
Query: 235 --------PNKCTPPNVE-NGILVSDNRSLFSLNEVVEFRCQPGFV-MKGPRRVKCQALN 284
N+C P + N DN F L + C+ GF+ +G + C ++
Sbjct: 783 NITYNTFGHNECPDPGIPINARRFGDN---FQLGSSISVICEEGFIKTQGTETITCILMD 839
Query: 285 ---KWEPELPSCSRVC----QPPPDVLHAERTQRDKDNFSPGQEVFY----SCEPGYDLR 333
W +P C C P V+ SPG +Y +CE +
Sbjct: 840 GKVMWSGLIPKCGAPCGGHFSAPSGVI-----------LSPGWPGYYKDSLNCEWVIEAE 888
Query: 334 GAASMRCT-PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFV-----CD 387
S++ T + EV + + LL V L + +F+ D
Sbjct: 889 PGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTD 948
Query: 388 EGFQLKGSSASY-CVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTV 446
G Y V S + +PV +GR G F G TV
Sbjct: 949 NSRSNNGFKIHYESVTVNTYSCLDPGIPV-------------HGRRYGHD---FSIGSTV 992
Query: 447 NYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGIL--GHCQAPDHFLFAKL 504
+++CD + + L E + C + N WS P P C L G + P
Sbjct: 993 SFSCD------SGYRLSHEEPLLC----EKNHWWSHPLPTCDALCGGDVRGPS------- 1035
Query: 505 KTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGM 564
GT L PE+Y P S+ C W+
Sbjct: 1036 -----------GTILS-PGYPEFY--PNSLNC----TWT--------------------- 1056
Query: 565 VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIAN 624
D+ G + ++ T H H +G S P+ + LPPTI
Sbjct: 1057 ----VDVTHGKGVQFNFHTFHLEDHHDYLLITENG-----SFTQPLARLTGSDLPPTINA 1107
Query: 625 G---------DFIST-----------------------------NRENFHY--GSVVTYR 644
G FIS +R F++ G +T+
Sbjct: 1108 GLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFS 1167
Query: 645 CNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRS 704
C+ G + L G I C +V WS P P+C+ + N E GIL+S N
Sbjct: 1168 CSSG------YRLEGTSEIICLGGGRRV--WSAPLPRCVAECGASATNNE-GILLSPNYP 1218
Query: 705 L 705
L
Sbjct: 1219 L 1219
Score = 37.0 bits (84), Expect = 0.20
Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 7/66 (10%)
Query: 1848 CPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTD----QGIWSQLDHY 1903
CP P + +NG IG SL G T+ + CD Y+L G I C WS
Sbjct: 446 CPDPGEPENGKRIGSDFSL---GSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPV 502
Query: 1904 CKEVNC 1909
CK C
Sbjct: 503 CKVKTC 508
Score = 36.6 bits (83), Expect = 0.26
Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 19/113 (16%)
Query: 1089 SVVTYRC----NLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVE 1144
+VVT+R + SRG K+F + + N+ + S P P E
Sbjct: 402 AVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPD--------PGEPE 453
Query: 1145 NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK----WEPELPSC 1193
NG + + FSL V+F C +V++G + + CQ + + W P C
Sbjct: 454 NGKRIGSD---FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 503
Score = 35.0 bits (79), Expect = 0.75
Identities = 25/105 (23%), Positives = 41/105 (39%), Gaps = 24/105 (22%)
Query: 193 YRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDN 252
++ PG F ++ E I SN + P+ P ENG + +
Sbjct: 419 FKLFPGKDNSNKFSILNEGGIKTASN--------------LCPD---PGEPENGKRIGSD 461
Query: 253 RSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK----WEPELPSC 293
FSL V+F C +V++G + + CQ + + W P C
Sbjct: 462 ---FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 503
Score = 33.9 bits (76), Expect = 1.7
Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 1728 NLQLGAKVSFVCDEGFRLKGRSASHCV-LAGMKALWNSSVPVCEQIFC 1774
+ LG+ V F CDE + L+G + C +A + A W+ PVC+ C
Sbjct: 461 DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 508
Score = 33.5 bits (75), Expect = 2.2
Identities = 15/48 (31%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Query: 1928 YHYGDYVTLKCEDGYTLEGSPWSQCQADD--RWDPPLAKCTSRTHDAL 1973
Y GD V+ +C+ GY+L+G C RW+ P+ C ++ A+
Sbjct: 2028 YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAM 2075
Score = 33.1 bits (74), Expect = 2.8
Identities = 24/86 (27%), Positives = 31/86 (36%), Gaps = 14/86 (16%)
Query: 287 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ--- 343
E + SC PP VL+ R F G ++ YSC GY L G + C
Sbjct: 132 ELQSSSCGNPGVPPKGVLYGTR-------FDVGDKIRYSCVTGYILDGHPQLTCIANSVN 184
Query: 344 -GDWSPAAPTCEVKSCDDFMGQLLNG 368
W P C +D G + G
Sbjct: 185 TASWDFPVPICR---AEDACGGTMRG 207
Score = 33.1 bits (74), Expect = 2.8
Identities = 24/86 (27%), Positives = 31/86 (36%), Gaps = 14/86 (16%)
Query: 737 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ--- 793
E + SC PP VL+ R F G ++ YSC GY L G + C
Sbjct: 132 ELQSSSCGNPGVPPKGVLYGTR-------FDVGDKIRYSCVTGYILDGHPQLTCIANSVN 184
Query: 794 -GDWSPAAPTCEVKSCDDFMGQLLNG 818
W P C +D G + G
Sbjct: 185 TASWDFPVPICR---AEDACGGTMRG 207
Score = 32.7 bits (73), Expect = 3.7
Identities = 21/77 (27%), Positives = 26/77 (33%), Gaps = 9/77 (11%)
Query: 612 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
Q CG P G T F G + Y C G + L G P + C +N
Sbjct: 134 QSSSCGNPGVPPKGVLYGTR---FDVGDKIRYSCVTG------YILDGHPQLTCIANSVN 184
Query: 672 VGIWSGPAPQCIIPNKC 688
W P P C + C
Sbjct: 185 TASWDFPVPICRAEDAC 201
Score = 32.7 bits (73), Expect = 3.7
Identities = 21/77 (27%), Positives = 26/77 (33%), Gaps = 9/77 (11%)
Query: 1062 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQ 1121
Q CG P G T F G + Y C G + L G P + C +N
Sbjct: 134 QSSSCGNPGVPPKGVLYGTR---FDVGDKIRYSCVTG------YILDGHPQLTCIANSVN 184
Query: 1122 VGIWSGPAPQCIIPNKC 1138
W P P C + C
Sbjct: 185 TASWDFPVPICRAEDAC 201
Score = 32.3 bits (72), Expect = 4.9
Identities = 20/73 (27%), Positives = 25/73 (34%), Gaps = 9/73 (12%)
Query: 166 CGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 225
CG P G T F G + Y C G + L G P + C +N W
Sbjct: 138 CGNPGVPPKGVLYGTR---FDVGDKIRYSCVTG------YILDGHPQLTCIANSVNTASW 188
Query: 226 SGPAPQCIIPNKC 238
P P C + C
Sbjct: 189 DFPVPICRAEDAC 201
Score = 31.6 bits (70), Expect = 8.3
Identities = 21/71 (29%), Positives = 26/71 (36%), Gaps = 11/71 (15%)
Query: 1187 EPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQ--- 1243
E + SC PP +L+G F G ++ YSC GY L G L C
Sbjct: 132 ELQSSSCGNPGVPPKGVLYGTR-------FDVGDKIRYSCVTGYILDGHPQLTCIANSVN 184
Query: 1244 -GDWSPEAPRC 1253
W P C
Sbjct: 185 TASWDFPVPIC 195
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 399 bits (1025), Expect = e-110
Identities = 476/1934 (24%), Positives = 720/1934 (37%), Gaps = 357/1934 (18%)
Query: 101 RKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGD-TVIWDNETP 159
R+SC +P + +NG + + GS + Y C GY L G S+ TCI+ D W+ P
Sbjct: 1698 RESCFDPGNIMNG-TRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1756
Query: 160 ICDRIPCGLPPTITNGDFISTNR-ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSN 218
C PCG T + G +S N +N+ G + C K F + G+ + TS
Sbjct: 1757 SC-HAPCGSRSTGSEGTVLSPNYPKNYSVG----HNCVYSIAVPKEFVVFGQFVFFQTSL 1811
Query: 219 DDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRV 278
D V ++ GP Q + + + + + +S + + F KG V
Sbjct: 1812 HDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQI-----TIRFTSVGPITAKGFHFV 1866
Query: 279 KCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASM 338
QA+ + CS V +P +R + F+ G V + C PGY L G+ ++
Sbjct: 1867 Y-QAVPRTSST--QCSSVPEP-------RFGRRIGNEFAVGSSVLFDCNPGYILHGSIAI 1916
Query: 339 RC----TPQGDWSPAAPTCEVKSCDDFM----GQLLNGRVLFPVNLQLGAKVDFVCDEGF 390
RC W+ + PTC + C + G +L+ P + L EG
Sbjct: 1917 RCETVPNSLAQWNDSLPTC-IVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGA 1975
Query: 391 QLKGSSASYCVLAGMESL-----------------------------------WNSSVPV 415
++ S+ +SL + S + V
Sbjct: 1976 GIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISV 2035
Query: 416 CEQIF-----------CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIG 464
F CP P +G G + + G V++ CD + L G
Sbjct: 2036 SAAGFHLEYTAIGLDSCPEPQTPSSGIKIG---DRYMVGDVVSFQCD------QGYSLQG 2086
Query: 465 ESTIRCTSDPQGNGVWSSPAPRC------------GILGHCQAPD--------------- 497
S I C P W+ P P C G++ P
Sbjct: 2087 HSHITCMPGPVRR--WNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLP 2144
Query: 498 -----HFLFAKLKTQT-------NASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSP 545
H F T+T + T + P+ FS T +L + S
Sbjct: 2145 IGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSD 2204
Query: 546 KDVCKR-----------KSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAE 594
K+ +SC P NG V + D VG I++ C G+ LIG+S+
Sbjct: 2205 YSQNKQGFHIVYQAYQLQSCPDPRPFRNGFV-IGNDFTVGQTISFECFPGYTLIGNSALT 2263
Query: 595 CILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTY---RCNPGSGG 651
C L G + +W+ P C+ + CG T NG S + + + R PG+G
Sbjct: 2264 C-LHGVSRNWNHPLPRCEAL-CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGI 2321
Query: 652 RKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEV 711
F ++ IY D + +W GP P + + S++S +
Sbjct: 2322 YINFTVLQTEPIY-----DFITVWDGPDQ--------NSPQIGQFSGNTALESVYSTSNQ 2368
Query: 712 VEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQE 771
+ + F G + A RVCQPPP V +AE D D F G
Sbjct: 2369 ILIKFHSDFTTSGFFVLSYHAYQ---------LRVCQPPPPVPNAEILTED-DEFEIGDI 2418
Query: 772 VFYSCEPGYDLRGAASMRCT--PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP------ 823
+ Y C PG+ L G A + C + A P C+V + + G +L P
Sbjct: 2419 IRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSY 2478
Query: 824 VNLQLGAKVDFVCDEGFQL-------------------KGSSASYCVLAGMESLWNSSVP 864
NLQ+ A ++G+ + G + VL + ++S+
Sbjct: 2479 PNLQMCA-WSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFN 2537
Query: 865 VCEQ-------------------------IFCPSPPVIPNG---RHTGKPLEVFPFGKAV 896
+ +C +P P+G TG L V
Sbjct: 2538 ITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQL-----NSVV 2592
Query: 897 NYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKT 956
+ C DRG F L+G+S+ C G W +P P C + C P K
Sbjct: 2593 RWAC----DRG--FRLVGKSSAVCRKSSYGYHAWDAPVPACQAIS-CGIP--------KA 2637
Query: 957 QTN----ASDFPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKDV--CKRKSCKTP 1007
TN +D+ +GT + Y C Y +T C + WS+ C +C +
Sbjct: 2638 PTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSI 2697
Query: 1008 PDPV--NGMVHVI--TDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQR 1063
+ +G ++ + + +++ +SC G+ +G +S EC+ +G T W + P CQ
Sbjct: 2698 NSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNG-TWSWRNERPYCQI 2756
Query: 1064 IPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVG 1123
I CG PT NG+ I T YGS + C+LG F LVG C S+ G
Sbjct: 2757 ISCGELPTPPNGNKIGTQTS---YGSTAIFTCDLG------FMLVGSAVRECLSS----G 2803
Query: 1124 IWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 1183
+WS +C+ + P + NG ++ +N + + V ++C PGF + G CQ
Sbjct: 2804 LWSESETRCLAGHCGIPELIVNGQVIGEN---YGYRDTVVYQCNPGFRLIGSSVRICQQD 2860
Query: 1184 NKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTP 1242
+ W +LPSC V C P ++G + + F+ V +SC GY ++G C
Sbjct: 2861 HNWSGQLPSCVPVSCGHPGSPIYGR---TSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQA 2917
Query: 1243 QGDWSPEAPRCAVKSCDD--------FLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKG 1294
WS P C V +C D ++ HG N G V + C+ G+ L G
Sbjct: 2918 NRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHG------NFTYGTVVFYDCNPGYFLFG 2971
Query: 1295 SSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHP 1354
SSV C G W+ +P C I C +P G P + G++ ++ H
Sbjct: 2972 SSVLICQPNGQ---WDKPLPECIMIDCGHP---------GVPPNAVLSGEKYTFGSTVHY 3019
Query: 1355 DRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDF 1414
+L+G+S+ C NG WS P C G C P S +
Sbjct: 3020 SCTGKRSLLGQSSRTCQL----NGHWSGSQPHCS-GDATGTCGDPGTPGHGSR----QES 3070
Query: 1415 EFPVGTSLNYECRPGY-FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTD 1473
F +++ Y C GY +CL N W+ + C+ CG P NG V
Sbjct: 3071 NFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDG 3130
Query: 1474 TQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSN 1533
T F S+V YSC EG+ L G C +G TW P C IISC P +NG Y +
Sbjct: 3131 TTFSSSVIYSCMEGYILSGPSVRQCTANG---TWSGTLPNCTIISCGDPGIPANGLRYGD 3187
Query: 1534 NRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTA 1593
+ + G V+Y C G EL G R CT G WS P C + T
Sbjct: 3188 D---YVVGQNVSYMCQPG----YTMELNGSRIRTCTIN----GTWSGVMPTCRAVTCPTP 3236
Query: 1594 PEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHC-SRVCQP 1652
P++ N R+ G F I + C PG+ + + C NG W ++P C + C
Sbjct: 3237 PQISNG-RLEGTN--FDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGD 3293
Query: 1653 PPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRC---TVK 1709
P G+ +F EV +SC + L G+++ C G WS +P C T
Sbjct: 3294 PGIPAQGKR---EGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQT 3350
Query: 1710 SCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVC 1769
SC++ G HG Q+G+ V F C +G L+G + C+ W+ P C
Sbjct: 3351 SCEN-PGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCL---PDLTWSGIQPEC 3406
Query: 1770 EQIFCPNPPAILNGRHTGTPFGDIP-YGKEISYACDTHPDRGMTFNLIGESSIR-CTSDP 1827
C P + G D+P +G + Y C F L G + R C SD
Sbjct: 3407 IPHSCKQPETPAHANVVGM---DLPSHGYTLIYTCQP------GFFLAGGTEHRVCRSD- 3456
Query: 1828 QGNGVWSSPAPRCE 1841
W+ P CE
Sbjct: 3457 ---NTWTGKVPICE 3467
Score = 321 bits (823), Expect = 4e-87
Identities = 274/992 (27%), Positives = 411/992 (41%), Gaps = 124/992 (12%)
Query: 1004 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAH-WSTKPPICQ 1062
C TP P +G + T Q+ S + ++C G RL+G SSA C S H W P CQ
Sbjct: 2569 CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2628
Query: 1063 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQV 1122
I CG+P NG ++T+ + G+ VTY CN G R EL + C S+
Sbjct: 2629 AISCGIPKAPTNGGILTTD---YLVGTRVTYFCNDGYRLSSK-ELT---TAVCQSD---- 2677
Query: 1123 GIWSG--PAPQCIIPNKCTPPNVENGILVSD-----NRSLFSLNEVVEFRCQPGFVMKGP 1175
G WS P+C++ T P++ + IL N S + V F C PG+ GP
Sbjct: 2678 GTWSNHNKTPRCVV---VTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGP 2734
Query: 1176 RRVKC--QALNKWEPELP-----SCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEP 1228
++C W E P SC + PP G T S G ++C+
Sbjct: 2735 ASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQT-------SYGSTAIFTCDL 2787
Query: 1229 GYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDE 1288
G+ L G+A C G WS RC C + +L + N V + C+
Sbjct: 2788 GFMLVGSAVRECLSSGLWSESETRCLAGHCG--IPELIVNGQVIGENYGYRDTVVYQCNP 2845
Query: 1289 GFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISY 1348
GFRL GSSV C W+ +P C + C +P + + GR +G + +++
Sbjct: 2846 GFRLIGSSVRICQ---QDHNWSGQLPSCVPVSCGHPGSPIYGRTSGN---GFNFNDVVTF 2899
Query: 1349 TCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPT 1408
+C+ + + + G + +C + N WS P P C++ +C P +
Sbjct: 2900 SCN------IGYLMQGPTKAQCQA----NRQWSHPPPMCKVV----NCSDPGIPANSKRE 2945
Query: 1409 IPINDFEFPVGTSLNYECRPGYFGKMFSIS---CLENLVWSSVEDNCRRKSCGPPPEPFN 1465
I F GT + Y+C PGYF +F S C N W C CG P P N
Sbjct: 2946 SKIEHGNFTYGTVVFYDCNPGYF--LFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPN 3003
Query: 1466 GMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICE---IISCEPP 1522
++ T FGSTV+YSC L+G S TC ++G+ W P C +C P
Sbjct: 3004 AVLSGEKYT-FGSTVHYSCTGKRSLLGQSSRTCQLNGH---WSGSQPHCSGDATGTCGDP 3059
Query: 1523 PTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPP 1582
T +G S ++F + V Y C TG + L G C + G W+
Sbjct: 3060 GTPGHG---SRQESNFRTKSTVRYACDTG------YILHGSEERTCLAN----GSWTGRQ 3106
Query: 1583 PRCISTNKCTAPEVE---NAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRW 1639
P C + +C P R+ G T + + + C G+++ G QC NG W
Sbjct: 3107 PECKAV-QCGNPGTTANGKVFRIDGT----TFSSSVIYSCMEGYILSGPSVRQCTANGTW 3161
Query: 1640 GPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSY--DLRGAASLHCTPQG 1697
LP+C+ + P I + L + D++ GQ V Y C+P Y +L G+ CT G
Sbjct: 3162 SGTLPNCTIISCGDPGI--PANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTING 3219
Query: 1698 DWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAG 1757
WS P C +C Q+ +GR L N G +S++C G+ L + CV G
Sbjct: 3220 TWSGVMPTCRAVTCPT-PPQISNGR-LEGTNFDWGFSISYICSPGYELSFPAVLTCVGNG 3277
Query: 1758 MKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIG 1817
W+ VP C FC +P G+ G F Y E+S++C+ F L+G
Sbjct: 3278 T---WSGEVPQCLPKFCGDPGIPAQGKREGKSF---IYQSEVSFSCN------FPFILVG 3325
Query: 1818 ESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYIC 1877
S+ C +D G WS +P C +C +P ++G + + G + + C
Sbjct: 3326 SSTRICQAD----GTWSGSSPHCIEPTQTSCENPGVPRHGSQ--NNTFGFQVGSVVQFHC 3379
Query: 1878 DPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNC---SFPLFMNGISKELEMKKVYHYGDYV 1934
G+LL G C WS + C +C P N + +L +G +
Sbjct: 3380 KKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLP-----SHGYTL 3434
Query: 1935 TLKCEDGYTLEGSPWSQ-CQADDRWDPPLAKC 1965
C+ G+ L G + C++D+ W + C
Sbjct: 3435 IYTCQPGFFLAGGTEHRVCRSDNTWTGKVPIC 3466
Score = 299 bits (766), Expect = 2e-80
Identities = 244/822 (29%), Positives = 336/822 (40%), Gaps = 94/822 (11%)
Query: 67 TYLNYECRPGYSGR-PFSIICLKNSVWTGAKDR--CRRKSCRNPPDPVNGMVHVIKGIQF 123
T + + C PGY G P SI CL N W+ +R C+ SC P P NG + +
Sbjct: 2719 TKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGN-KIGTQTSY 2777
Query: 124 GSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRE 183
GS ++C G+ L+GS+ C+ SG +W C CG+P I NG I E
Sbjct: 2778 GSTAIFTCDLGFMLVGSAVRECLSSG---LWSESETRCLAGHCGIPELIVNGQVIG---E 2831
Query: 184 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 243
N+ Y V Y+CNPG F L+G C + + WSG P C+ P C P
Sbjct: 2832 NYGYRDTVVYQCNPG------FRLIGSSVRICQQDHN----WSGQLPSCV-PVSCGHPG- 2879
Query: 244 ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPD 302
+ I + + F+ N+VV F C G++M+GP + +CQA +W P C V C P
Sbjct: 2880 -SPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGI 2938
Query: 303 VLHAERTQR-DKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF 361
+++R + + NF+ G VFY C PGY L G++ + C P G W P C + C
Sbjct: 2939 PANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGH- 2997
Query: 362 MGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVC--EQI 419
+ VL G+ V + C L G S+ C L G W+ S P C +
Sbjct: 2998 -PGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGH---WSGSQPHCSGDAT 3053
Query: 420 FCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGV 479
P P H + F TV Y CD T + L G C + NG
Sbjct: 3054 GTCGDPGTPG--HGSRQESNFRTKSTVRYACD------TGYILHGSEERTCLA----NGS 3101
Query: 480 WSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPI-----GTSLKYECRPEY-YGRPFS 533
W+ P C + C P T N F I +S+ Y C Y P
Sbjct: 3102 WTGRQPECKAV-QCGNPG--------TTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSV 3152
Query: 534 ITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGH--RLIGHS 591
C N WS C SC P P NG+ + D VG ++Y C G+ L G
Sbjct: 3153 RQCTANGTWSGTLPNCTIISCGDPGIPANGLRYG-DDYVVGQNVSYMCQPGYTMELNGSR 3211
Query: 592 SAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGG 651
C ++G WS P C+ + C PP I+NG T NF +G ++Y C+PG
Sbjct: 3212 IRTCTINGT---WSGVMPTCRAVTCPTPPQISNGRLEGT---NFDWGFSISYICSPG--- 3262
Query: 652 RKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNR--SLFSLN 709
+EL + C N G WSG PQC +P C P GI R F
Sbjct: 3263 ---YELSFPAVLTCVGN----GTWSGEVPQC-LPKFCGDP----GIPAQGKREGKSFIYQ 3310
Query: 710 EVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC----SRVCQPPPDVLHAERTQRDKDN 765
V F C F++ G CQA W P C C+ P H +Q +
Sbjct: 3311 SEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHG--SQNNTFG 3368
Query: 766 FSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVN 825
F G V + C+ G+ L+G+ + C P WS P C SC + V+
Sbjct: 3369 FQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQ-PETPAHANVVGMDL 3427
Query: 826 LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCE 867
G + + C GF L G + + ++ W VP+CE
Sbjct: 3428 PSHGYTLIYTCQPGFFLAGGTEHR--VCRSDNTWTGKVPICE 3467
Score = 295 bits (755), Expect = 3e-79
Identities = 446/1993 (22%), Positives = 711/1993 (35%), Gaps = 411/1993 (20%)
Query: 188 GSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGI 247
GS + Y CNPG + L G + C + + + W P P CI +G
Sbjct: 1374 GSTIIYGCNPG------YTLHGSSLLKCMTGERRA--WDYPLPSCIAECGGRFKGESSGR 1425
Query: 248 LVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPD----- 302
++S N + RC + V Q L RV PP+
Sbjct: 1426 ILSPGYPFPYDNNL---RCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLL 1482
Query: 303 --------------VLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSP 348
L+ Q D D FY + G+ ++ ++S+ + P
Sbjct: 1483 KEISGSLIPEGIHSTLNIVTIQFDTD--------FYISKSGFAIQFSSSVATACR---DP 1531
Query: 349 AAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESL 408
P ++ D GR + G V F CD G++L+G C+
Sbjct: 1532 GVPMNGTRNGD--------GR-------EPGDTVVFQCDPGYELQGEERITCIQVENRYF 1576
Query: 409 WNSSVPVCEQIFCPSPPVIP-NGRHTGKPLEV--------FPFGKTVNYTCDPHPDRGTS 459
W S PVC + P G TG + +P + ++T + D S
Sbjct: 1577 WQPSPPVC---------IAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVIS 1627
Query: 460 FDLIGESTIRCTSDPQGNG--VWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGT 517
I S +P + ++ P ++G Q +KL + +S +
Sbjct: 1628 LAFISFSI-----EPNYDFLYIYDGPDSNSPLIGSFQD------SKLPERIESSSNTMHL 1676
Query: 518 SLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRI 577
+ + + Y G F + L R+SC P + +NG + D ++GS +
Sbjct: 1677 AFRSDGSVSYTG--FHLEYKAKL----------RESCFDPGNIMNG-TRLGMDYKLGSTV 1723
Query: 578 NYSCTTGHRLIGHSSAECILSGNAAH-WSTKPPICQRIPCGLPPTIANGDFISTNR-ENF 635
Y C G+ L G+S+ CI+ + W+ P C PCG T + G +S N +N+
Sbjct: 1724 TYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHA-PCGSRSTGSEGTVLSPNYPKNY 1782
Query: 636 HYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVEN 695
G + C K F + G+ + TS D V ++ GP Q + + + +
Sbjct: 1783 SVG----HNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGE 1838
Query: 696 GILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLH 755
+ +S + + F KG V QA+ + CS V +P
Sbjct: 1839 SLPLSSGNQI-----TIRFTSVGPITAKGFHFVY-QAVPRTSST--QCSSVPEP------ 1884
Query: 756 AERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRC----TPQGDWSPAAPTCEVKSCDDF 811
+R + F+ G V + C PGY L G+ ++RC W+ + PTC + C
Sbjct: 1885 -RFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTC-IVPCGGI 1942
Query: 812 M----GQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESL--------- 858
+ G +L+ P + L EG ++ S+ +SL
Sbjct: 1943 LTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNN 2002
Query: 859 --------------------------WNSSVPVCEQIF-----------CPSPPVIPNGR 881
+ S + V F CP P +G
Sbjct: 2003 APRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGI 2062
Query: 882 HTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC---- 937
G + + G V++ CD + L G S I C P W+ P P C
Sbjct: 2063 KIG---DRYMVGDVVSFQCDQ------GYSLQGHSHITCMPGPVRR--WNYPIPICLAQC 2111
Query: 938 --------GILGHCQAPD--------------------HFLFAKLKTQT-------NASD 962
G++ P H F T+T +
Sbjct: 2112 GGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGS 2171
Query: 963 FPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKR-----------KSCKTPPDPV 1011
T + P+ FS T +L + S K+ +SC P
Sbjct: 2172 SETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFR 2231
Query: 1012 NGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPT 1071
NG V + D VG I++ C G+ LIG+S+ C L G + +W+ P C+ + CG T
Sbjct: 2232 NGFV-IGNDFTVGQTISFECFPGYTLIGNSALTC-LHGVSRNWNHPLPRCEAL-CGGNIT 2288
Query: 1072 IANGDFISTNRENFHYGSVVTYRCNLGSRGRKV---FELVGEPSIYCTSNDDQVGIWSGP 1128
NG S + + + G + F ++ IY D + +W GP
Sbjct: 2289 AMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIY-----DFITVWDGP 2343
Query: 1129 APQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 1188
P + + S++S + + + F G + A
Sbjct: 2344 DQNS--------PQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQL--- 2392
Query: 1189 ELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTP----QG 1244
RVCQPPP + + E + D F G + Y C PG+ L G A L C Q
Sbjct: 2393 ------RVCQPPPPVPNAEIL-TEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQM 2445
Query: 1245 DWSPEAPRCAVKSCDDFLGQLPHGRVLFP------LNLQLGAKVSFVCDEGFRLK----- 1293
D +P P C V + L G +L P NLQ+ A S ++G+ +
Sbjct: 2446 DGAP--PVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAW-SISVEKGYNITMFVEF 2502
Query: 1294 --------------GSSVSHCVLVGMRSLWNNSVPVCEH--------------------- 1318
G ++ VL+ + ++++ + +
Sbjct: 2503 FQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRI 2562
Query: 1319 ----IFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDP 1374
+C P + +G G + + + CD RG F L+G+S+ C
Sbjct: 2563 RYIAFYCSTPESPPHGYIISQTGGQL--NSVVRWACD----RG--FRLVGKSSAVCRKSS 2614
Query: 1375 HGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGY---F 1431
+G W +P P C+ ++ G K P + ++ VGT + Y C GY
Sbjct: 2615 YGYHAWDAPVPACQ-AISCGIPKAPTNGGILTT-------DYLVGTRVTYFCNDGYRLSS 2666
Query: 1432 GKMFSISCLENLVWSSVEDN--CRRKSCGPPPEPF---NGMVHI--NTDTQFGSTVNYSC 1484
++ + C + WS+ C +C P F +G I + ++ + V +SC
Sbjct: 2667 KELTTAVCQSDGTWSNHNKTPRCVVVTC-PSINSFILEHGRWRIVNGSHYEYKTKVVFSC 2725
Query: 1485 NEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVV 1544
+ G+ +G S CL +G +W + P C+IISC PT NG+ +TS+ G+
Sbjct: 2726 DPGYHGLGPASIECLPNGT-WSWRNERPYCQIISCGELPTPPNGNKIGT-QTSY--GSTA 2781
Query: 1545 TYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPG 1604
+ C G F LVG C S G+WS RC++ + C PE+ +V G
Sbjct: 2782 IFTCDLG------FMLVGSAVRECLSS----GLWSESETRCLAGH-CGIPELIVNGQVIG 2830
Query: 1605 NRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPPPEILHGEHTL 1663
+ + + ++C PGF ++GS CQ + W +LP C V C P ++G
Sbjct: 2831 EN--YGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGR--- 2885
Query: 1664 SHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDD--------FL 1715
+ + F+ V +SC Y ++G C WS P C V +C D
Sbjct: 2886 TSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRE 2945
Query: 1716 GQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCP 1775
++ HG N G V + C+ G+ L G S C G W+ +P C I C
Sbjct: 2946 SKIEHG------NFTYGTVVFYDCNPGYFLFGSSVLICQPNGQ---WDKPLPECIMIDCG 2996
Query: 1776 NPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSS 1835
+P N +G + +G + Y+C +L+G+SS C Q NG WS
Sbjct: 2997 HPGVPPNAVLSGEKY---TFGSTVHYSCTGKR------SLLGQSSRTC----QLNGHWSG 3043
Query: 1836 PAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQG 1895
P C C P +G S + T+ Y CD GY+L G C G
Sbjct: 3044 SQPHCSGDATGTCGDPGTPGHG---SRQESNFRTKSTVRYACDTGYILHGSEERTCLANG 3100
Query: 1896 IWSQLDHYCKEVNCSFPLFMNGISKELEMKKV--YHYGDYVTLKCEDGYTLEGSPWSQCQ 1953
W+ CK V C P G + ++ ++ + V C +GY L G QC
Sbjct: 3101 SWTGRQPECKAVQCGNP----GTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCT 3156
Query: 1954 ADDRWDPPLAKCT 1966
A+ W L CT
Sbjct: 3157 ANGTWSGTLPNCT 3169
Score = 272 bits (695), Expect = 3e-72
Identities = 266/1003 (26%), Positives = 398/1003 (39%), Gaps = 129/1003 (12%)
Query: 43 CNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYS--GRPFSIICLKNS----VWTGAK 96
C+ PE P + T + + + + C G+ G+ S +C K+S W
Sbjct: 2569 CSTPESPPHGYIISQTGG---QLNSVVRWACDRGFRLVGKS-SAVCRKSSYGYHAWDAPV 2624
Query: 97 DRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWD- 155
C+ SC P P NG + + G+++ Y C GYRL T + D W
Sbjct: 2625 PACQAISCGIPKAPTNGGI-LTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGT-WSN 2682
Query: 156 -NETPICDRIPCGLPPTIT-----NGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVG 209
N+TP C + C P+I +G + N ++ Y + V + C+PG G +G
Sbjct: 2683 HNKTPRCVVVTC---PSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHG------LG 2733
Query: 210 EPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPG 269
SI C N W P C I + P NG + S S F C G
Sbjct: 2734 PASIECLPNG--TWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGS---TAIFTCDLG 2788
Query: 270 FVMKGPRRVKCQALNKW-EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEP 328
F++ G +C + W E E + C P +++ Q +N+ V Y C P
Sbjct: 2789 FMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNG---QVIGENYGYRDTVVYQCNP 2845
Query: 329 GYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDE 388
G+ L G++ C +WS P+C SC G + GR V F C+
Sbjct: 2846 GFRLIGSSVRICQQDHNWSGQLPSCVPVSC-GHPGSPIYGRT-SGNGFNFNDVVTFSCNI 2903
Query: 389 GFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGK-PLEVFPFGKTVN 447
G+ ++G + + C W+ P+C+ + C P + N + K F +G V
Sbjct: 2904 GYLMQGPTKAQC---QANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVF 2960
Query: 448 YTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGIL--GHCQAPDHFLFAKLK 505
Y C+P + L G S + C Q NG W P P C ++ GH P + + + K
Sbjct: 2961 YDCNP------GYFLFGSSVLIC----QPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEK 3010
Query: 506 TQTNASDFPIGTSLKYEC--RPEYYGRPFSITCLDNLVWSSPKDVCK---RKSCKTPPDP 560
+ G+++ Y C + G+ S TC N WS + C +C P P
Sbjct: 3011 -------YTFGSTVHYSCTGKRSLLGQS-SRTCQLNGHWSGSQPHCSGDATGTCGDPGTP 3062
Query: 561 VNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPP 620
+G ++ + S + Y+C TG+ L G C+ +G+ W+ + P C+ + CG P
Sbjct: 3063 GHGS-RQESNFRTKSTVRYACDTGYILHGSEERTCLANGS---WTGRQPECKAVQCGNPG 3118
Query: 621 TIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 680
T ANG + F S V Y C G + L G CT+N G WSG P
Sbjct: 3119 TTANGKVFRIDGTTF--SSSVIYSCMEG------YILSGPSVRQCTAN----GTWSGTLP 3166
Query: 681 QCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMK--GPRRVKCQALNKWEP 738
C I + P NG+ D+ + + + V + CQPG+ M+ G R C W
Sbjct: 3167 NCTIISCGDPGIPANGLRYGDD---YVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSG 3223
Query: 739 ELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWS 797
+P+C V C PP + + + + NF G + Y C PGY+L A + C G WS
Sbjct: 3224 VMPTCRAVTCPTPPQISNG---RLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWS 3280
Query: 798 PAAPTCEVKSCDD----FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLA 853
P C K C D G+ ++ ++V F C+ F L GSS C
Sbjct: 3281 GEVPQCLPKFCGDPGIPAQGKREGKSFIYQ------SEVSFSCNFPFILVGSSTRICQAD 3334
Query: 854 GMESLWNSSVPVC---EQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSF 910
G W+ S P C Q C +P V +G FG V H +G
Sbjct: 3335 G---TWSGSSPHCIEPTQTSCENPGVPRHGSQNN------TFGFQVGSVVQFHCKKGHL- 3384
Query: 911 DLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPI-GTSL 969
L G +T C D WS P C I C+ P+ A + D P G +L
Sbjct: 3385 -LQGSTTRTCLPDL----TWSGIQPEC-IPHSCKQPETPAHANVV----GMDLPSHGYTL 3434
Query: 970 KYECRPEYY--GRPFSITCLDNLVWSSPKDVCKRKSCKTPPDP 1010
Y C+P ++ G C + W+ +C+ S DP
Sbjct: 3435 IYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDP 3477
Score = 80.1 bits (196), Expect = 2e-14
Identities = 93/409 (22%), Positives = 153/409 (37%), Gaps = 99/409 (24%)
Query: 1457 CGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCL-VSGNNVTWDKKAPICE 1515
C P EP NG I +D GSTV +SC+E + L G+ S TC ++ W P+C+
Sbjct: 486 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 544
Query: 1516 IISCE-----PPPTISNGDF---YSNNR------TSFHNGTVVT-----------YQCHT 1550
+ +C P T ++ +F Y +N T+ + V+ Y T
Sbjct: 545 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 604
Query: 1551 GPDGEQLFELVGERSIYCTS-KDDQVGVWSSPPPRCISTN--------KCTAPEVEN-AI 1600
DG ++ + + S D + SS + T+ K E+E +
Sbjct: 605 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 664
Query: 1601 RVPGNRSF-------FTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHC-----SR 1648
PG + F+ +++RF CQ GF ++G ++ CQ N +W +P C S
Sbjct: 665 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSN 724
Query: 1649 VCQPPPEILHGEHTLSHQDNFS--------PGQEVFYSCEPSYDLRGAASLHCTPQGDWS 1700
P +L ++ + +N + PG + S +DL GD S
Sbjct: 725 FTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDGD-S 782
Query: 1701 PEAPRCTVKSCDDFLGQLPHGRVLLPL--------------------------------- 1727
PE+P + + L +L L
Sbjct: 783 PESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPIN 842
Query: 1728 ------NLQLGAKVSFVCDEGF-RLKGRSASHCVLAGMKALWNSSVPVC 1769
N QLG+ +S +C+EGF + +G C+L K +W+ +P C
Sbjct: 843 ARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 891
Score = 69.7 bits (169), Expect = 3e-11
Identities = 134/603 (22%), Positives = 207/603 (34%), Gaps = 149/603 (24%)
Query: 1156 FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC-----SRVCQPPPEILHGEHTP 1210
FS +V+ F CQ GF + G + + CQ N+W +P C S P +L ++
Sbjct: 680 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPE 739
Query: 1211 SHQDNFS--------PGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAP----------- 1251
+ +N + PG + S +DL GD SPE+P
Sbjct: 740 GYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDGD-SPESPILGTFTGAEVP 797
Query: 1252 ----------RCAVKSCDDFLGQ------------------LPHGRVLFPLNLQLGAKVS 1283
R ++ G+ +P F N QLG+ +S
Sbjct: 798 SHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSIS 857
Query: 1284 FVCDEGF-RLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDI-- 1340
+C+EGF + +G+ C+L+ + +W+ +P C P G H PSG I
Sbjct: 858 VICEEGFIKTQGTETITCILMDGKVMWSGLIPKC------GAPC---GGHFSAPSGVILS 908
Query: 1341 ---PYGKEISYTC------DPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSV 1391
P + S C +P +TF + H SP L
Sbjct: 909 PGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSP-----LLG 963
Query: 1392 RAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDN 1451
+ P QF F+S ++F + + T+ N G+ + + SV N
Sbjct: 964 SYNGTQVP-QFLFSS-----SNFIYLLFTTDNSRSNNGF-----------KIHYESVTVN 1006
Query: 1452 CRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKA 1511
SC P P +G D GSTV++SC+ G+RL C N W
Sbjct: 1007 --TYSCLDPGIPVHGR-RYGHDFSIGSTVSFSCDSGYRLSHEEPLLC---EKNHWWSHPL 1060
Query: 1512 PICEIIS----CEPPPTISN---GDFYSNN-----RTSFHNGTVVTYQCHT-GPDGEQLF 1558
P C+ + P TI + +FY N+ +G V + HT + +
Sbjct: 1061 PTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDY 1120
Query: 1559 ELVGERSIYCTSKDDQVGVWSSPPP--------------RCISTNKCT------------ 1592
L+ E + G S PP R IS +
Sbjct: 1121 LLITENGSFTQPLARLTG--SDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYN 1178
Query: 1593 -APEVENAIRVPGNRSFFT--LTEIIRFRCQPGFVMVGSHTVQCQTNGR--WGPKLPHCS 1647
P + I G+R F + + + F C G+ + G+ + C GR W LP C
Sbjct: 1179 LEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCV 1238
Query: 1648 RVC 1650
C
Sbjct: 1239 AEC 1241
Score = 69.3 bits (168), Expect = 4e-11
Identities = 134/623 (21%), Positives = 213/623 (34%), Gaps = 134/623 (21%)
Query: 706 FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC-----QPPPDVLHAERTQ 760
FS +V+ F CQ GF + G + + CQ N+W +P C C P VL + +
Sbjct: 680 FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPE 739
Query: 761 RDKDNFS--------PGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFM 812
+N + PG + S +DL GD SP +P + +
Sbjct: 740 GYGNNLNCIWTIISDPGSRIHLSFND-FDLESQFDFLAVKDGD-SPESPILGTFTGAEVP 797
Query: 813 GQLL-NGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFC 871
L N +L +++F D +G + +Y E C
Sbjct: 798 SHLTSNSHIL---------RLEFQADHSMSGRGFNITYNTFGHNE--------------C 834
Query: 872 PSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 931
P P + N R G + F G +++ C+ G TI C G +WS
Sbjct: 835 PDPGIPINARRFG---DNFQLGSSISVICEEG-----FIKTQGTETITCIL-MDGKVMWS 885
Query: 932 SPAPRCGIL--GHCQA---------------------------PDHFL---FAKLKTQTN 959
P+CG GH A P H + F + +T+ N
Sbjct: 886 GLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELN 945
Query: 960 ASDFPI--GTSLKYECRPEYYGRP-----FSITCLDNLVWSSPKD-------------VC 999
+ G +L Y G FS + L++++
Sbjct: 946 YDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTV 1005
Query: 1000 KRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPP 1059
SC P PV+G + D +GS +++SC +G+RL S E +L WS P
Sbjct: 1006 NTYSCLDPGIPVHGRRYG-HDFSIGSTVSFSCDSGYRL---SHEEPLLCEKNHWWSHPLP 1061
Query: 1060 ICQRIPCGLPPTIANGDFISTNRENFHYGSV-VTYRCNLGSRGRKVFELVGEPSIYCTSN 1118
C + CG +G +S F+ S+ T+ ++ + G+ V + + +
Sbjct: 1062 TCDAL-CGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDV-THGKGV--QFNFHTFHLEDH 1117
Query: 1119 DDQVGI---WSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP 1175
D + I S P + PP + G+ + FR Q F+
Sbjct: 1118 HDYLLITENGSFTQPLARLTGSDLPPTINAGLYGN-------------FRAQLRFI--SD 1162
Query: 1176 RRVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGA 1235
+ + N E C+ P +G NF G + +SC GY L G
Sbjct: 1163 FSISYEGFNITFSEYN--LEPCEDPGIPQYGSRIGF---NFGIGDTLTFSCSSGYRLEGT 1217
Query: 1236 ASLHCTPQGD--WSPEAPRCAVK 1256
+ + C G WS PRC +
Sbjct: 1218 SEIICLGGGRRVWSAPLPRCVAE 1240
Score = 65.9 bits (159), Expect = 4e-10
Identities = 203/866 (23%), Positives = 304/866 (35%), Gaps = 179/866 (20%)
Query: 910 FDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSL 969
F+LIGE +I C Q N WS+ P C +F L T P+GT L
Sbjct: 694 FELIGEKSIVC----QENNQWSANIPIC------------IFPCLSNFTA----PMGTVL 733
Query: 970 KYECRPEYYGRPFSITCLDNLV---------------WSSPKDVCKRKSCKTPPDPVNGM 1014
+ PE YG ++ C+ ++ S D K +P P+ G
Sbjct: 734 SPDY-PEGYGN--NLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILG- 789
Query: 1015 VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPC-GLPPTIA 1073
T +V S + + H L A+ +SG + + P G+P
Sbjct: 790 --TFTGAEVPSHLT---SNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIP---- 840
Query: 1074 NGDFISTNR--ENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 1131
I+ R +NF GS ++ C G + G +I C D +V +WSG P+
Sbjct: 841 ----INARRFGDNFQLGSSISVICEEG-----FIKTQGTETITCILMDGKV-MWSGLIPK 890
Query: 1132 CIIPNKCTPP-NVENGILVSDNRSLF---SLNEVVEFRCQPGFVMKGPRRVKCQALNKWE 1187
C P C + +G+++S + SLN +PG +K LN
Sbjct: 891 CGAP--CGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDV 948
Query: 1188 PELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWS 1247
E+ + P +G P + S + ++ + G +H
Sbjct: 949 LEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGF-KIHY------- 1000
Query: 1248 PEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRS 1307
E+ SC D G HGR + + +G+ VSF CD G+RL S +L
Sbjct: 1001 -ESVTVNTYSCLD-PGIPVHGR-RYGHDFSIGSTVSFSCDSGYRL---SHEEPLLCEKNH 1054
Query: 1308 LWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDI---------PYGKEISYTCDPHPDRGM 1358
W++ +P C+ A+ G G PSG I P ++T D +G+
Sbjct: 1055 WWSHPLPTCD--------ALCGGDVRG-PSGTILSPGYPEFYPNSLNCTWTVDVTHGKGV 1105
Query: 1359 TFNLIGESTIRCTSDPHG------NGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPIN 1412
FN T D H NG ++ P R S F + I+
Sbjct: 1106 QFNF---HTFHL-EDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFIS 1161
Query: 1413 DFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINT 1472
DF S++YE F FS LE C P P G I
Sbjct: 1162 DF------SISYEG----FNITFSEYNLE--------------PCEDPGIPQYGS-RIGF 1196
Query: 1473 DTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYS 1532
+ G T+ +SC+ G+RL G+ CL G V W P C + C T + G S
Sbjct: 1197 NFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRV-WSAPLPRC-VAECGASATNNEGILLS 1254
Query: 1533 -NNRTSFHNGTVVTY--QCHTGPD---GEQLFELV-GERSIYCTSKDDQ---VGVWSSPP 1582
N ++ N Y Q G + F L G+ KD +G ++
Sbjct: 1255 PNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGAS 1314
Query: 1583 PRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPK 1642
R + T N + + N E GF +V + +
Sbjct: 1315 MRGL-----TLSSTSNQLWLEFNSDTEGTDE--------GFQLVYTSF-----------E 1350
Query: 1643 LPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCT--PQGDWS 1700
L HC P I + +S Q +F+ G + Y C P Y L G++ L C + W
Sbjct: 1351 LSHCE-----DPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSSLLKCMTGERRAWD 1404
Query: 1701 PEAPRCTVKSCDDFLGQLPHGRVLLP 1726
P C + F G+ GR+L P
Sbjct: 1405 YPLPSCIAECGGRFKGE-SSGRILSP 1429
Score = 65.1 bits (157), Expect = 7e-10
Identities = 152/670 (22%), Positives = 244/670 (36%), Gaps = 117/670 (17%)
Query: 183 ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP- 241
+NF GS ++ C G + G +I C D +V +WSG P+C P C
Sbjct: 848 DNFQLGSSISVICEEG-----FIKTQGTETITCILMDGKV-MWSGLIPKCGAP--CGGHF 899
Query: 242 NVENGILVSDNRSLF---SLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQ 298
+ +G+++S + SLN +PG +K +++ EL
Sbjct: 900 SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIK-------ITFERFQTELNYDVLEVH 952
Query: 299 PPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSC 358
P++L + Q +F S Y L + R + T SC
Sbjct: 953 DGPNLLSP--LLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSC 1010
Query: 359 DDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQ 418
D G ++GR + + +G+ V F CD G++L C W+ +P C+
Sbjct: 1011 LD-PGIPVHGR-RYGHDFSIGSTVSFSCDSGYRLSHEEPLLCE---KNHWWSHPLPTCDA 1065
Query: 419 IFCPSPPVIPNGR--HTGKPLEVFPFGKTVNYTCDPHPDRGTSFD-------------LI 463
+ C P+G G P E +P +T D +G F+ LI
Sbjct: 1066 L-CGGDVRGPSGTILSPGYP-EFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLI 1123
Query: 464 GESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYEC 523
E+ + G P G+ G+ +A F+ SDF S+ YE
Sbjct: 1124 TENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFI----------SDF----SISYE- 1168
Query: 524 RPEYYGRPFSITCLD-NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCT 582
F+IT + NL + C+ P P G + + +G + +SC+
Sbjct: 1169 -------GFNITFSEYNL-----------EPCEDPGIPQYGS-RIGFNFGIGDTLTFSCS 1209
Query: 583 TGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNR----ENFHYG 638
+G+RL G S C L G WS P C CG T G +S N EN H
Sbjct: 1210 SGYRLEGTSEIIC-LGGGRRVWSAPLPRCVA-ECGASATNNEGILLSPNYPLNYENNHE- 1266
Query: 639 SVVTYRCNPGSG---GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVEN 695
+ + + G G + F L + D + I+ G + T ++
Sbjct: 1267 CIYSIQVQAGKGINISARTFHL---------AQGDVLKIYDGKDKTTHLLGAFTGASMRG 1317
Query: 696 GILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLH 755
L S + L+ +EF +G + V EL C P +
Sbjct: 1318 LTLSSTSNQLW-----LEFNSDTEGTDEGFQLVYTSF------ELSHCE-----DPGIPQ 1361
Query: 756 AERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT--PQGDWSPAAPTCEVKSCDDFMG 813
D+ +F+ G + Y C PGY L G++ ++C + W P+C + F G
Sbjct: 1362 FGYKISDQGHFA-GSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKG 1420
Query: 814 QLLNGRVLFP 823
+ +GR+L P
Sbjct: 1421 E-SSGRILSP 1429
Score = 63.9 bits (154), Expect = 2e-09
Identities = 107/455 (23%), Positives = 163/455 (35%), Gaps = 100/455 (21%)
Query: 104 CRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCI-ISGDTVIWDNETPICD 162
C +P +P NG + GS +++SC + Y L G+ S TC I+ W + P+C
Sbjct: 486 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 544
Query: 163 RIPC-----GLPPTITNGDF----------------ISTNRE---NFH-YGSVVTY-RCN 196
C G T T+ +F ++TN+ NF + + Y
Sbjct: 545 VKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLT 604
Query: 197 PGSGG-----RKVFE-LVGE--PSIYCTSN---------DDQVG-IWSGPAPQCIIPNKC 238
G GG R V + L G P + + + D+ VG + + I C
Sbjct: 605 IGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 664
Query: 239 TPPNVE-NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC---- 293
P GI D FS +V+ F CQ GF + G + + CQ N+W +P C
Sbjct: 665 GDPGTPLYGIREGDG---FSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPC 721
Query: 294 -SRVCQPPPDVLHAERTQRDKDNFS--------PGQEVFYSCEPGYDLRGAASMRCTPQG 344
S P VL + + +N + PG + S +DL G
Sbjct: 722 LSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFN-DFDLESQFDFLAVKDG 780
Query: 345 DWSPAAPTCEVKSCDDFMGQLL-NGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLA 403
D SP +P + + L N +L +++F D +G + +Y
Sbjct: 781 D-SPESPILGTFTGAEVPSHLTSNSHIL---------RLEFQADHSMSGRGFNITYNTFG 830
Query: 404 GMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLI 463
E CP P + N R G + F G +++ C+
Sbjct: 831 HNE--------------CPDPGIPINARRFG---DNFQLGSSISVICEE-----GFIKTQ 868
Query: 464 GESTIRCTSDPQGNGVWSSPAPRCGIL--GHCQAP 496
G TI C G +WS P+CG GH AP
Sbjct: 869 GTETITCIL-MDGKVMWSGLIPKCGAPCGGHFSAP 902
Score = 60.8 bits (146), Expect = 1e-08
Identities = 136/619 (21%), Positives = 200/619 (32%), Gaps = 134/619 (21%)
Query: 384 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIF-CPSPPVIPNGRHTGKPLEVFPF 442
F C GF+L G + C + W++++P+C IF C S P G +P
Sbjct: 688 FECQFGFELIGEKSIVCQ---ENNQWSANIPIC--IFPCLSNFTAPMGTVLSPD---YPE 739
Query: 443 GKTVNYTC------DPHPDRGTSF-DLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQA 495
G N C DP SF D ES + G+ S +P G +
Sbjct: 740 GYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD---SPESPILGTFTGAEV 796
Query: 496 PDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCK 555
P H T+ S L+++ GR F+IT + C
Sbjct: 797 PSHL--------TSNSHI---LRLEFQADHSMSGRGFNITY----------NTFGHNECP 835
Query: 556 TPPDPVNGMVHVITDIQVGSRINYSCTTGH-RLIGHSSAECILSGNAAHWSTKPPICQRI 614
P P+N + Q+GS I+ C G + G + CIL WS P C
Sbjct: 836 DPGIPINAR-RFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGA- 893
Query: 615 PCGLPPTIANGDFISTNRENFHYGSVV---TYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
PCG + +G +S ++ S+ PG + FE N D
Sbjct: 894 PCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFE-----RFQTELNYDV 948
Query: 672 VGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ 731
+ + GP + V L S + ++ L R GF + +
Sbjct: 949 LEVHDGPNLLSPLLGSYNGTQVPQ-FLFSSSNFIYLLFTTDNSRSNNGFKI----HYESV 1003
Query: 732 ALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT 791
+N + C P +H R D FS G V +SC+ GY L + C
Sbjct: 1004 TVNTYS---------CLDPGIPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCE 1051
Query: 792 PQGDWSPAAPTCEVKSCDDFMGQLLNGRVL-------FPVNLQLGAKVDFVCDEGFQ--- 841
WS PTC+ D G +G +L +P +L VD +G Q
Sbjct: 1052 KNHWWSHPLPTCDALCGGDVRGP--SGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNF 1109
Query: 842 --------------------------LKGSSASYCVLAGMESLWNSSVPVCEQIF----- 870
L GS + AG+ + + +
Sbjct: 1110 HTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEG 1169
Query: 871 ------------CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTI 918
C P + G G F G + ++C + + L G S I
Sbjct: 1170 FNITFSEYNLEPCEDPGIPQYGSRIGFN---FGIGDTLTFSC------SSGYRLEGTSEI 1220
Query: 919 RCTSDPQGNGVWSSPAPRC 937
C G VWS+P PRC
Sbjct: 1221 ICLGG--GRRVWSAPLPRC 1237
Score = 60.5 bits (145), Expect = 2e-08
Identities = 142/626 (22%), Positives = 212/626 (33%), Gaps = 125/626 (19%)
Query: 553 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL-SGNAAHWSTKPPIC 611
SC P P G+++ T VG +I YSC TG+ L GH CI S N A W PIC
Sbjct: 177 SCGNPGVPPKGVLYG-TRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPIC 235
Query: 612 Q-RIPCGLPPTIANGDFISTNREN-FHYGSVVTYR--CNPGSGGRKVFELVGEPSIYCTS 667
+ CG ++G S + N +H + T+ PG +F
Sbjct: 236 RAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIF-----TDFQMEE 290
Query: 668 NDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVE-------FRCQPGF 720
D + I P + PP + N++ L+ V + F
Sbjct: 291 KYDYLEIEGSEPPTIWLSGMNIPPP------IISNKNWLRLHFVTDSNHRYRGFSAPYQG 344
Query: 721 VMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY 780
L + V P DV + T S Q V +
Sbjct: 345 SSTLTHTTSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVT----- 399
Query: 781 DLRGAASMRCTPQGDWSP-AAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEG 839
LR + T + SP A T + Q+ + L V ++ +DF G
Sbjct: 400 SLRNSGLDPNTSKDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFK-SRG 458
Query: 840 FQL---KGSSASYCVL--AGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGK 894
F+L K +S + +L G+++ N CP P NG+ G F G
Sbjct: 459 FKLFPGKDNSNKFSILNEGGIKTASN---------LCPDPGEPENGKRIGSD---FSLGS 506
Query: 895 AVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGIL---GHCQAPDHFLF 951
V ++CD + L G +I C + WS P C + + Q P
Sbjct: 507 TVQFSCD------EDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFT 560
Query: 952 A---KLKTQTNASDFPIGTSLKYECRPEYYGRPF-------SITCLDNLVWSSPKDVCKR 1001
+ + +NA + T++ + F ++T D P+ V +
Sbjct: 561 SPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQV 620
Query: 1002 KSCKTPPDPVNGM-----VHVITDIQVGS---RINYSCTTGHRLIGHSSAECILSGNTAH 1053
+ PD + M +H+ TD VGS ++NY
Sbjct: 621 LTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYK----------------------- 657
Query: 1054 WSTKPPICQRIPCGLPPT----IANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVG 1109
++ CG P T I GD S NR+ V+ + C G FEL+G
Sbjct: 658 ------EIEKESCGDPGTPLYGIREGDGFS-NRD------VLRFECQFG------FELIG 698
Query: 1110 EPSIYCTSNDDQVGIWSGPAPQCIIP 1135
E SI C N+ WS P CI P
Sbjct: 699 EKSIVCQENNQ----WSANIPICIFP 720
Score = 60.1 bits (144), Expect = 2e-08
Identities = 104/479 (21%), Positives = 156/479 (32%), Gaps = 110/479 (22%)
Query: 69 LNYECRPGYSGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIK 128
L ++ SGR F+I + C +P P+N Q GS I
Sbjct: 809 LEFQADHSMSGRGFNI----------TYNTFGHNECPDPGIPINAR-RFGDNFQLGSSIS 857
Query: 129 YSCTKGY-RLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHY 187
C +G+ + G+ + TCI+ V+W P C PCG + +G +S ++
Sbjct: 858 VICEEGFIKTQGTETITCILMDGKVMWSGLIPKCG-APCGGHFSAPSGVILSPGWPGYYK 916
Query: 188 GSV---VTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGP---APQCIIPNKCTPP 241
S+ PG + FE N D + + GP +P N P
Sbjct: 917 DSLNCEWVIEAEPGHSIKITFE-----RFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVP 971
Query: 242 NVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPP 301
L S + ++ L R GF + + +N + C P
Sbjct: 972 Q----FLFSSSNFIYLLFTTDNSRSNNGFKI----HYESVTVNTYS---------CLDPG 1014
Query: 302 DVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDF 361
+H R D FS G V +SC+ GY L + C WS PTC+ D
Sbjct: 1015 IPVHGRRYGHD---FSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDV 1071
Query: 362 MGQLLNGRVL-------FPVNLQLGAKVDFVCDEGFQ----------------------- 391
G +G +L +P +L VD +G Q
Sbjct: 1072 RGP--SGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSF 1129
Query: 392 ------LKGSSASYCVLAGMESLWNSSVPVCEQIF-----------------CPSPPVIP 428
L GS + AG+ + + + C P +
Sbjct: 1130 TQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQ 1189
Query: 429 NGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 487
G G F G T+ ++C + + L G S I C G VWS+P PRC
Sbjct: 1190 YGSRIGFN---FGIGDTLTFSC------SSGYRLEGTSEIICLGG--GRRVWSAPLPRC 1237
Score = 59.7 bits (143), Expect = 3e-08
Identities = 139/652 (21%), Positives = 216/652 (33%), Gaps = 142/652 (21%)
Query: 104 CRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 163
C +P P G + G + +SC+ GYRL G+S C + G +W P C
Sbjct: 1182 CEDPGIPQYGS-RIGFNFGIGDTLTFSCSSGYRLEGTSEIIC-LGGGRRVWSAPLPRC-V 1238
Query: 164 IPCGLPPTITNGDFIS----TNRENFHYGSVVTYRCNPGSG---GRKVFELVGEPSIYCT 216
CG T G +S N EN H + + + G G + F L
Sbjct: 1239 AECGASATNNEGILLSPNYPLNYENNH-ECIYSIQVQAGKGINISARTFHL--------- 1288
Query: 217 SNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 276
+ D + I+ G + T ++ L S + L+ +EF +G +
Sbjct: 1289 AQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLW-----LEFNSDTEGTDEGFQ 1343
Query: 277 RVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAA 336
V EL C P + D+ +F+ G + Y C PGY L G++
Sbjct: 1344 LVYTSF------ELSHCE-----DPGIPQFGYKISDQGHFA-GSTIIYGCNPGYTLHGSS 1391
Query: 337 SMRCT--PQGDWSPAAPTCEVKSCDDFMGQLLNGRVL-----FPVNLQLGAKVDFVCDEG 389
++C + W P+C + F G+ +GR+L FP + L D G
Sbjct: 1392 LLKCMTGERRAWDYPLPSCIAECGGRFKGE-SSGRILSPGYPFPYDNNLRCMWMIEVDPG 1450
Query: 390 ------FQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPF- 442
F + AS+ +L +W+ + S +IP G H+ + F
Sbjct: 1451 NIVSLQFLAFDTEASHDIL----RVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFD 1506
Query: 443 ----------------------------------------GKTVNYTCDPHPDRGTSFDL 462
G TV + CDP ++L
Sbjct: 1507 TDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDP------GYEL 1560
Query: 463 IGESTIRCTSDPQGNGVWSSPAPRC---------GILGHCQAPDHFLFAKLKTQTNASDF 513
GE I C + W P C G G +P+ F + D+
Sbjct: 1561 QGEERITCI-QVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPN---FPHPYPHSRDCDW 1616
Query: 514 PIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQV 573
I + Y + FSI + ++ PD + ++ D ++
Sbjct: 1617 TITVNADYVISLAFIS--FSIEPNYDFLY-----------IYDGPDSNSPLIGSFQDSKL 1663
Query: 574 GSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRE 633
RI S T H L S +G + K R C P I NG +
Sbjct: 1664 PERIESSSNTMH-LAFRSDGSVSYTGFHLEYKAK----LRESCFDPGNIMNGTRLGM--- 1715
Query: 634 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIP 685
++ GS VTY C+ G + L G ++ C DD W+ P C P
Sbjct: 1716 DYKLGSTVTYYCDAG------YVLQGYSTLTCIMGDDGRPGWNRALPSCHAP 1761
Score = 49.3 bits (116), Expect = 4e-05
Identities = 70/277 (25%), Positives = 98/277 (35%), Gaps = 34/277 (12%)
Query: 1004 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNT-AHWSTKPPICQ 1062
C P +P NG + +D +GS + +SC + L G S C A WS P+C+
Sbjct: 486 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 544
Query: 1063 RIPCGLPPTIANGDFISTNRENFHYGS------VVTYRCNLGSRGRKVFELVGEPSIYCT 1116
CG +G F S N F Y S V+T N + FE Y T
Sbjct: 545 VKTCGSNLQGPSGTFTSPNFP-FQYDSNAQCVWVIT-AVNTNKVIQINFEEFDLEIGYDT 602
Query: 1117 SNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 1176
G P + P+ ++VS + ++ + E GF
Sbjct: 603 LTIGDGGEVGDPRTVLQVLTGSFVPD----LIVSMSSQMWLHLQTDESVGSVGF------ 652
Query: 1177 RVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAA 1236
+N E E SC P I G D FS + + C+ G++L G
Sbjct: 653 -----KVNYKEIEKESCGDPGTPLYGIREG-------DGFSNRDVLRFECQFGFELIGEK 700
Query: 1237 SLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFP 1273
S+ C WS P C +F P G VL P
Sbjct: 701 SIVCQENNQWSANIPICIFPCLSNFTA--PMGTVLSP 735
Score = 48.1 bits (113), Expect = 9e-05
Identities = 140/645 (21%), Positives = 212/645 (32%), Gaps = 136/645 (21%)
Query: 1360 FNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVG 1419
F LIGE +I C N WS+ P C FP S +F P+G
Sbjct: 694 FELIGEKSIVCQE----NNQWSANIPICI-------------FPCLS------NFTAPMG 730
Query: 1420 TSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRR-------------------KSCGPP 1460
T L+ + GY + N +W+ + D R K P
Sbjct: 731 TVLSPDYPEGYGNNL-------NCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSP 783
Query: 1461 PEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCE 1520
P G T + S + S + RL + G N+T++ C
Sbjct: 784 ESPILGTF---TGAEVPSHLT-SNSHILRLEFQADHSMSGRGFNITYNTFGHN----ECP 835
Query: 1521 PPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSS 1580
P N + +N F G+ ++ C G + G +I C D +V +WS
Sbjct: 836 DPGIPINARRFGDN---FQLGSSISVICEEG-----FIKTQGTETITCILMDGKV-MWSG 886
Query: 1581 PPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWG 1640
P+C + I PG ++ + C+ H+++ T R+
Sbjct: 887 LIPKCGAPCGGHFSAPSGVILSPGWPGYYKDS----LNCEWVIEAEPGHSIKI-TFERFQ 941
Query: 1641 PKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWS 1700
+L + P +L L + Q +F S Y L +
Sbjct: 942 TELNYDVLEVHDGPNLL--SPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIH 999
Query: 1701 PEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKA 1760
E+ SC D G HGR + +G+ VSF CD G+RL S +L
Sbjct: 1000 YESVTVNTYSCLD-PGIPVHGR-RYGHDFSIGSTVSFSCDSGYRL---SHEEPLLCEKNH 1054
Query: 1761 LWNSSVPVCE------------QIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDT-HP 1807
W+ +P C+ I P P T D+ +GK + + T H
Sbjct: 1055 WWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHL 1114
Query: 1808 DRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSL- 1866
+ + LI E NG ++ P R PP I G Y L
Sbjct: 1115 EDHHDYLLITE-----------NGSFTQPLARL-----TGSDLPPTINAGLYGNFRAQLR 1158
Query: 1867 YLPGMTISYICDPGYLLVGKGFIF--CTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEM 1924
++ +ISY G+ + + C D GI Y + +F +
Sbjct: 1159 FISDFSISY---EGFNITFSEYNLEPCEDPGI----PQYGSRIGFNFGI----------- 1200
Query: 1925 KKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDR--WDPPLAKCTS 1967
GD +T C GY LEG+ C R W PL +C +
Sbjct: 1201 ------GDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVA 1239
Score = 47.0 bits (110), Expect = 2e-04
Identities = 68/277 (24%), Positives = 99/277 (35%), Gaps = 34/277 (12%)
Query: 554 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNA-AHWSTKPPICQ 612
C P +P NG + +D +GS + +SC + L G S C A WS P+C+
Sbjct: 486 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 544
Query: 613 RIPCGLPPTIANGDFISTNRENFHYGS------VVTYRCNPGSGGRKVFELVGEPSIYCT 666
CG +G F S N F Y S V+T N + FE Y T
Sbjct: 545 VKTCGSNLQGPSGTFTSPNFP-FQYDSNAQCVWVIT-AVNTNKVIQINFEEFDLEIGYDT 602
Query: 667 SNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 726
G P + P+ ++VS + ++ + E GF
Sbjct: 603 LTIGDGGEVGDPRTVLQVLTGSFVPD----LIVSMSSQMWLHLQTDESVGSVGF------ 652
Query: 727 RVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAA 786
+N E E SC P + R+ D FS + + C+ G++L G
Sbjct: 653 -----KVNYKEIEKESCGDPGTPLYGI-------REGDGFSNRDVLRFECQFGFELIGEK 700
Query: 787 SMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP 823
S+ C WS P C +F + G VL P
Sbjct: 701 SIVCQENNQWSANIPICIFPCLSNFTAPM--GTVLSP 735
Score = 46.6 bits (109), Expect = 2e-04
Identities = 25/66 (37%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 97 DRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCII-SGDTVIWD 155
+ + SC NP P G+++ + G +I+YSC GY L G TCI S +T WD
Sbjct: 171 EELQSSSCGNPGVPPKGVLYGTR-FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWD 229
Query: 156 NETPIC 161
PIC
Sbjct: 230 FPVPIC 235
Score = 46.6 bits (109), Expect = 2e-04
Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
Query: 1450 DNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLV-SGNNVTWD 1508
+ + SCG P P G+++ T G + YSC G+ L G P TC+ S N +WD
Sbjct: 171 EELQSSSCGNPGVPPKGVLY-GTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWD 229
Query: 1509 KKAPIC 1514
PIC
Sbjct: 230 FPVPIC 235
Score = 45.1 bits (105), Expect = 7e-04
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Query: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 162
+CR+P P+NG + G + G + + C GY L G TCI + W P+C
Sbjct: 1527 ACRDPGVPMNGTRNG-DGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC- 1584
Query: 163 RIPCGLPPTITNGDFISTN 181
PCG T ++G +S N
Sbjct: 1585 IAPCGGNLTGSSGFILSPN 1603
Score = 44.3 bits (103), Expect = 0.001
Identities = 83/385 (21%), Positives = 138/385 (35%), Gaps = 90/385 (23%)
Query: 1416 FPVGTSLNYECRPGYFGKMF-SISCLENLV----WSSVEDNCRRK-SCGPPPEPFNGMVH 1469
F VG + Y C GY ++C+ N V W CR + +CG +G++
Sbjct: 194 FDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGII- 252
Query: 1470 INTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPP------- 1522
+ F + + + + + ++ P T + + ++K EI EPP
Sbjct: 253 --SSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGM 310
Query: 1523 ----PTISNGDFY-------SNNR-----TSFHNGTVVTYQCHTGPDGEQLFELVGERSI 1566
P ISN ++ SN+R + + +T+ TG E G ++
Sbjct: 311 NIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGELEEHNRTTTGAIAV 370
Query: 1567 YCT-----------------SKDDQVGVWS---------------SPPPRCISTNKCTAP 1594
T S++ +V V S SP P + + T
Sbjct: 371 ASTPADVTVSSVTAVTIHRLSEEQRVQVTSLRNSGLDPNTSKDGLSPHP---ADTQSTRR 427
Query: 1595 EVENAIRVPGNRSFFTLTEIIR---------FRCQPGFVMVGSHTVQCQTNGRWGPKLPH 1645
+A ++ + +T ++ F+ PG S+ G +
Sbjct: 428 RPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPG--KDNSNKFSILNEGG----IKT 481
Query: 1646 CSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGD----WSP 1701
S +C P E +G+ S +FS G V +SC+ Y L+GA S+ C + WS
Sbjct: 482 ASNLCPDPGEPENGKRIGS---DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSD 538
Query: 1702 EAPRCTVKSCDDFLGQLPHGRVLLP 1726
P C VK+C L Q P G P
Sbjct: 539 HRPVCKVKTCGSNL-QGPSGTFTSP 562
Score = 44.3 bits (103), Expect = 0.001
Identities = 31/91 (34%), Positives = 43/91 (47%), Gaps = 8/91 (8%)
Query: 1187 EPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD- 1245
E + + S +C P E +G+ S +FS G V +SC+ Y L+GA S+ C +
Sbjct: 476 EGGIKTASNLCPDPGEPENGKRIGS---DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEV 532
Query: 1246 ---WSPEAPRCAVKSCDDFLGQLPHGRVLFP 1273
WS P C VK+C L Q P G P
Sbjct: 533 FAAWSDHRPVCKVKTCGSNL-QGPSGTFTSP 562
Score = 43.9 bits (102), Expect = 0.002
Identities = 26/76 (34%), Positives = 38/76 (50%), Gaps = 7/76 (9%)
Query: 287 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGD- 345
E + + S +C PD E +R +FS G V +SC+ Y L+GA S+ C +
Sbjct: 476 EGGIKTASNLC---PDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEV 532
Query: 346 ---WSPAAPTCEVKSC 358
WS P C+VK+C
Sbjct: 533 FAAWSDHRPVCKVKTC 548
Score = 38.9 bits (89), Expect = 0.052
Identities = 146/721 (20%), Positives = 228/721 (31%), Gaps = 238/721 (33%)
Query: 101 RKSCRNPPDPVNGMVHVIKGIQFGSQ--IKYSCTKGYRLIGSSSATCIISGDTVIWDNET 158
++SC +P P+ G + +G F ++ +++ C G+ LIG S C + W
Sbjct: 661 KESCGDPGTPLYG---IREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ---WSANI 714
Query: 159 PICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPS--IYCT 216
PIC PC T G +S + Y G+ ++ ++ +P I+ +
Sbjct: 715 PIC-IFPCLSNFTAPMGTVLSPD-----------YPEGYGNNLNCIWTIISDPGSRIHLS 762
Query: 217 SND-------DQVGIWSGPAPQCII----------------------------------- 234
ND D + + G +P+ I
Sbjct: 763 FNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGF 822
Query: 235 --------PNKCTPPNVE-NGILVSDNRSLFSLNEVVEFRCQPGFV-MKGPRRVKCQALN 284
N+C P + N DN F L + C+ GF+ +G + C ++
Sbjct: 823 NITYNTFGHNECPDPGIPINARRFGDN---FQLGSSISVICEEGFIKTQGTETITCILMD 879
Query: 285 ---KWEPELPSCSRVC----QPPPDVLHAERTQRDKDNFSPGQEVFY----SCEPGYDLR 333
W +P C C P V+ SPG +Y +CE +
Sbjct: 880 GKVMWSGLIPKCGAPCGGHFSAPSGVI-----------LSPGWPGYYKDSLNCEWVIEAE 928
Query: 334 GAASMRCT-PQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFV-----CD 387
S++ T + EV + + LL V L + +F+ D
Sbjct: 929 PGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTD 988
Query: 388 EGFQLKGSSASY-CVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTV 446
G Y V S + +PV +GR G F G TV
Sbjct: 989 NSRSNNGFKIHYESVTVNTYSCLDPGIPV-------------HGRRYGHD---FSIGSTV 1032
Query: 447 NYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGIL--GHCQAPDHFLFAKL 504
+++CD + + L E + C + N WS P P C L G + P
Sbjct: 1033 SFSCD------SGYRLSHEEPLLC----EKNHWWSHPLPTCDALCGGDVRGPS------- 1075
Query: 505 KTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGM 564
GT L PE+Y P S+ C W+
Sbjct: 1076 -----------GTILS-PGYPEFY--PNSLNC----TWT--------------------- 1096
Query: 565 VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIAN 624
D+ G + ++ T H H +G S P+ + LPPTI
Sbjct: 1097 ----VDVTHGKGVQFNFHTFHLEDHHDYLLITENG-----SFTQPLARLTGSDLPPTINA 1147
Query: 625 G---------DFIST-----------------------------NRENFHY--GSVVTYR 644
G FIS +R F++ G +T+
Sbjct: 1148 GLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFS 1207
Query: 645 CNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRS 704
C+ G + L G I C +V WS P P+C+ + N E GIL+S N
Sbjct: 1208 CSSG------YRLEGTSEIICLGGGRRV--WSAPLPRCVAECGASATNNE-GILLSPNYP 1258
Query: 705 L 705
L
Sbjct: 1259 L 1259
Score = 37.0 bits (84), Expect = 0.20
Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 7/66 (10%)
Query: 1848 CPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTD----QGIWSQLDHY 1903
CP P + +NG IG SL G T+ + CD Y+L G I C WS
Sbjct: 486 CPDPGEPENGKRIGSDFSL---GSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPV 542
Query: 1904 CKEVNC 1909
CK C
Sbjct: 543 CKVKTC 548
Score = 36.6 bits (83), Expect = 0.26
Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 19/113 (16%)
Query: 1089 SVVTYRC----NLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVE 1144
+VVT+R + SRG K+F + + N+ + S P P E
Sbjct: 442 AVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPD--------PGEPE 493
Query: 1145 NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK----WEPELPSC 1193
NG + + FSL V+F C +V++G + + CQ + + W P C
Sbjct: 494 NGKRIGSD---FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 543
Score = 35.0 bits (79), Expect = 0.75
Identities = 25/105 (23%), Positives = 41/105 (39%), Gaps = 24/105 (22%)
Query: 193 YRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDN 252
++ PG F ++ E I SN + P+ P ENG + +
Sbjct: 459 FKLFPGKDNSNKFSILNEGGIKTASN--------------LCPD---PGEPENGKRIGSD 501
Query: 253 RSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK----WEPELPSC 293
FSL V+F C +V++G + + CQ + + W P C
Sbjct: 502 ---FSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVC 543
Score = 33.9 bits (76), Expect = 1.7
Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 1728 NLQLGAKVSFVCDEGFRLKGRSASHCV-LAGMKALWNSSVPVCEQIFC 1774
+ LG+ V F CDE + L+G + C +A + A W+ PVC+ C
Sbjct: 501 DFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTC 548
Score = 33.5 bits (75), Expect = 2.2
Identities = 15/48 (31%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Query: 1928 YHYGDYVTLKCEDGYTLEGSPWSQCQADD--RWDPPLAKCTSRTHDAL 1973
Y GD V+ +C+ GY+L+G C RW+ P+ C ++ A+
Sbjct: 2068 YMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAM 2115
Score = 33.1 bits (74), Expect = 2.8
Identities = 24/86 (27%), Positives = 31/86 (36%), Gaps = 14/86 (16%)
Query: 287 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ--- 343
E + SC PP VL+ R F G ++ YSC GY L G + C
Sbjct: 172 ELQSSSCGNPGVPPKGVLYGTR-------FDVGDKIRYSCVTGYILDGHPQLTCIANSVN 224
Query: 344 -GDWSPAAPTCEVKSCDDFMGQLLNG 368
W P C +D G + G
Sbjct: 225 TASWDFPVPICR---AEDACGGTMRG 247
Score = 33.1 bits (74), Expect = 2.8
Identities = 24/86 (27%), Positives = 31/86 (36%), Gaps = 14/86 (16%)
Query: 737 EPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ--- 793
E + SC PP VL+ R F G ++ YSC GY L G + C
Sbjct: 172 ELQSSSCGNPGVPPKGVLYGTR-------FDVGDKIRYSCVTGYILDGHPQLTCIANSVN 224
Query: 794 -GDWSPAAPTCEVKSCDDFMGQLLNG 818
W P C +D G + G
Sbjct: 225 TASWDFPVPICR---AEDACGGTMRG 247
Score = 32.7 bits (73), Expect = 3.7
Identities = 21/77 (27%), Positives = 26/77 (33%), Gaps = 9/77 (11%)
Query: 612 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQ 671
Q CG P G T F G + Y C G + L G P + C +N
Sbjct: 174 QSSSCGNPGVPPKGVLYGTR---FDVGDKIRYSCVTG------YILDGHPQLTCIANSVN 224
Query: 672 VGIWSGPAPQCIIPNKC 688
W P P C + C
Sbjct: 225 TASWDFPVPICRAEDAC 241
Score = 32.7 bits (73), Expect = 3.7
Identities = 21/77 (27%), Positives = 26/77 (33%), Gaps = 9/77 (11%)
Query: 1062 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQ 1121
Q CG P G T F G + Y C G + L G P + C +N
Sbjct: 174 QSSSCGNPGVPPKGVLYGTR---FDVGDKIRYSCVTG------YILDGHPQLTCIANSVN 224
Query: 1122 VGIWSGPAPQCIIPNKC 1138
W P P C + C
Sbjct: 225 TASWDFPVPICRAEDAC 241
Score = 32.3 bits (72), Expect = 4.9
Identities = 20/73 (27%), Positives = 25/73 (34%), Gaps = 9/73 (12%)
Query: 166 CGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 225
CG P G T F G + Y C G + L G P + C +N W
Sbjct: 178 CGNPGVPPKGVLYGTR---FDVGDKIRYSCVTG------YILDGHPQLTCIANSVNTASW 228
Query: 226 SGPAPQCIIPNKC 238
P P C + C
Sbjct: 229 DFPVPICRAEDAC 241
Score = 31.6 bits (70), Expect = 8.3
Identities = 21/71 (29%), Positives = 26/71 (36%), Gaps = 11/71 (15%)
Query: 1187 EPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQ--- 1243
E + SC PP +L+G F G ++ YSC GY L G L C
Sbjct: 172 ELQSSSCGNPGVPPKGVLYGTR-------FDVGDKIRYSCVTGYILDGHPQLTCIANSVN 224
Query: 1244 -GDWSPEAPRC 1253
W P C
Sbjct: 225 TASWDFPVPIC 235
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 358 bits (920), Expect = 2e-98
Identities = 493/2172 (22%), Positives = 774/2172 (35%), Gaps = 478/2172 (22%)
Query: 104 CRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDR 163
C +P P G +G + + YSC GY + GS++ TC+ SGD +WD P C
Sbjct: 1218 CEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCL-SGDRRVWDKPLPSCIA 1276
Query: 164 IPCGLPPTITNGDFISTNR-----ENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSN 218
G T+G +S N H ++ +PG F + +
Sbjct: 1277 ECGGQIHAATSGRILSPGYPAPYDNNLHCTWII--EADPGKTISLHFIVFDTEMAH---- 1330
Query: 219 DDQVGIWSGPAPQCIIPNK----------------------------------------- 237
D + +W GP I+ +
Sbjct: 1331 -DILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIA 1389
Query: 238 --CTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK---WEPELP 291
C P + +NG D+R + V F+C PG+ ++G ++ C LN W+P+ P
Sbjct: 1390 ATCNDPGMPQNGTRYGDSREA---GDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPP 1446
Query: 292 SCSRVCQ-----PPPDVLHAERTQRDKDNFSPGQE---------------VF--YSCEPG 329
+C C P +L Q + PG+E +F ++ EP
Sbjct: 1447 TCIAACGGNLTGPAGVILSPNYPQP----YPPGKECDWRVKVNPDFVIALIFKSFNMEPS 1502
Query: 330 YDLR-------GAASMRCTPQGDWSP----------------------AAPTCEVK---- 356
YD + + + QG +P + E K
Sbjct: 1503 YDFLHIYEGEDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPR 1562
Query: 357 -SCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVL-AGMESLWNSSVP 414
+C D G ++NG + + +LG+ + + CD G+++ S+ CV+ A + W+ +P
Sbjct: 1563 EACFD-PGNIMNGTRV-GTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLP 1620
Query: 415 VCEQIFCPSPPVIPNGRHTGKPLEV----FPFGKTVNYTCDPHPDRGTSFDLIGESTIRC 470
C P G++TG V +P T C F + G+
Sbjct: 1621 SCN---APC-----GGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQ 1672
Query: 471 TSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTS----LKYECRPE 526
T+ ++ H QA L + L + P+ TS L++ +
Sbjct: 1673 TALNDLAELFDGT--------HAQAR---LLSSLSGSHSGETLPLATSNQILLRFSAKSG 1721
Query: 527 YYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHR 586
R F + + P+ C + P+P G + ++ GS + + C G+
Sbjct: 1722 ASARGFHF-----VYQAVPRT--SDTQCSSVPEPRYGR-RIGSEFSAGSIVRFECNPGYL 1773
Query: 587 LIGHSSAECILSGNA-AHWSTKPPICQRIPCGLPPTIANGDFIST-------NRENFHYG 638
L G ++ C NA A W+ P C +PC T G +S N N +
Sbjct: 1774 LQGSTALHCQSVPNALAQWNDTIPSCV-VPCSGNFTQRRGTILSPGYPEPYGNNLNCIWK 1832
Query: 639 SVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSG---PAPQCIIPNKCTPPNVEN 695
+VT GSG + + S N D + I G AP+ + T P + N
Sbjct: 1833 IIVT----EGSGIQ-----IQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLN 1883
Query: 696 GILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLH 755
S+ L +++ K CQ EP LPS S
Sbjct: 1884 S--TSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQ-----EPALPSNSI---------- 1926
Query: 756 AERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQG--DWSPAAPTCEVKSCDDFMG 813
+ D + + + CEPGY L+G + + C P W+ +P C + +C +
Sbjct: 1927 -----KIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLC-IATCGGTLS 1980
Query: 814 QLLNGRVL-------FPVNLQL----------GAKVDFV-----CDEGF----------- 840
L G +L +P NL GA + F+ + F
Sbjct: 1981 TL-GGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQNGPYHTS 2039
Query: 841 ----QLKGSSASYCVLAGMESL--------------WNSSVPVCEQIFCPSPPVIPNGRH 882
Q G+ +L+ + + E CP PP NG
Sbjct: 2040 PMIGQFSGTDLPAALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDPPPFQNGYM 2099
Query: 883 TGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGH 942
V G++V++ C P + LIG + C N W+ P PR
Sbjct: 2100 INSDYSV---GQSVSFECYP------GYILIGHPVLTCQHGINRN--WNYPFPR------ 2142
Query: 943 CQAPDHFLFAKLKTQTNASDFPIGTSLKYECR-----PEYYGRPFSITCLDN-------L 990
C AP + + FP + +C P +G + T L
Sbjct: 2143 CDAPCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIA 2202
Query: 991 VWSSPKD-------------------------------------------VCKRKSCKTP 1007
VW P + K C+ P
Sbjct: 2203 VWDGPDQNSPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFHAFQLKKCQPP 2262
Query: 1008 PD-PVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPC 1066
P P M+ D ++G + Y C G+ L+G C LS + P + P
Sbjct: 2263 PAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPA 2322
Query: 1067 GLPPTIANGDFISTNRENFHYGS------------------VVTYRCNL---------GS 1099
T ++G +S ++ S V T++ GS
Sbjct: 2323 NEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGS 2382
Query: 1100 RGRKVFELV-----GEPSIYCTSNDDQVGIWSGP-------------APQCIIPNKCTPP 1141
G+ +V E S + + ++ WS AP C + T P
Sbjct: 2383 SGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSL----THP 2438
Query: 1142 NVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ----ALNKWEPELPSCSRV- 1196
GIL NR+ ++ V + C+PG+ M G C+ + +W+ P C V
Sbjct: 2439 LKNGGIL---NRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVS 2495
Query: 1197 CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGA--ASLHCTPQGDWSPEA--PR 1252
C P +G T + F+ +V Y C G+ L + A+ C G WS + P
Sbjct: 2496 CGIPESPGNGSFTGNE---FTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPT 2552
Query: 1253 CAVKSCDDFLGQLPHG---RVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLW 1309
C +C QL R++ + GA+V C G+ L+G + C G W
Sbjct: 2553 CKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGT---W 2609
Query: 1310 N--NSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGEST 1367
N + P C I C + NG GT + YG +TC+ + L+G
Sbjct: 2610 NIGDERPSCRVISCGSLSFPPNGNKIGTLT---VYGATAIFTCNTG------YTLVGSHV 2660
Query: 1368 IRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECR 1427
C + NG+WS RC AGHC +P+ P + I + F + ++ Y+C
Sbjct: 2661 RECLA----NGLWSGSETRC----LAGHCGSPD--PIVNGHISGDGFSYR--DTVVYQCN 2708
Query: 1428 PGYFGKMFSIS-CLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNE 1486
PG+ S+ CL++ WS C +CG P P +G + ++ VN++CN
Sbjct: 2709 PGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTN-GSEFNLNDVVNFTCNT 2767
Query: 1487 GFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYS--NNRTSFHNGTVV 1544
G+ L G C +G W P C +++C P + N + N SF G +
Sbjct: 2768 GYLLQGVSRAQCRSNGQ---WSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSI 2824
Query: 1545 TYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPG 1604
Y C G F L+G ++ C + G+W P+C++ + C P V + G
Sbjct: 2825 LYHCKKG------FYLLGSSALTCMAN----GLWDRSLPKCLAIS-CGHPGVPANAVLTG 2873
Query: 1605 NRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSR----VCQPPPEILHGE 1660
FT ++ + C+ ++G+ T CQ + W LPHC+ C P HG
Sbjct: 2874 E--LFTYGAVVHYSCRGSESLIGNDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAHGS 2931
Query: 1661 HTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPH 1720
D+F + +SCE + LRG+ C G WS P C SC + G +
Sbjct: 2932 RL---GDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSCGN-PGTPTN 2987
Query: 1721 GRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAI 1780
G ++ + + V + C EG++ G HC G W + P C I C +P +
Sbjct: 2988 GMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGT---WTGTAPDCTIISCGDPGTL 3044
Query: 1781 LNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRC 1840
NG GT D + K +SY C+ G + ++IRCT D G W+ P C
Sbjct: 3045 ANGIQFGT---DFTFNKTVSYQCNP----GYVMEAVTSATIRCTKD----GRWNPSKPVC 3093
Query: 1841 ELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQL 1900
+ + CP PP +QNG G S + G +ISY C GY L + C +G+W
Sbjct: 3094 KAVL---CPQPPPVQNGTVEG---SDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGE 3147
Query: 1901 DHYCKEVNCSFPLFMNGISKELEMK-KVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWD 1959
C V C P GI E + K + Y V +C+ + L GS CQAD W
Sbjct: 3148 IPQCLPVFCGDP----GIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWS 3203
Query: 1960 PPLAKCTSRTHD 1971
C H+
Sbjct: 3204 GIQPTCIDPAHN 3215
Score = 350 bits (897), Expect = 1e-95
Identities = 364/1377 (26%), Positives = 544/1377 (39%), Gaps = 220/1377 (15%)
Query: 102 KSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPIC 161
++C +PP NG + + G + + C GY LIG TC G W+ P C
Sbjct: 2086 QNCPDPPPFQNGYM-INSDYSVGQSVSFECYPGYILIGHPVLTC-QHGINRNWNYPFPRC 2143
Query: 162 DRIPCGLPPTITNGDFISTNRENFH---YGSVVTYRCNPGSGGRKVFELVGEPSIYCTSN 218
D PCG T NG S + + + PG G F L+ ++
Sbjct: 2144 D-APCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAV----- 2197
Query: 219 DDQVGIWSGP---APQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP 275
+D + +W GP +PQ + + T S N+ L + +F FV
Sbjct: 2198 NDYIAVWDGPDQNSPQLGVFSGNTALETAYS---STNQVLLKFHS--DFSNGGFFV---- 2248
Query: 276 RRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 335
LN +L C QPPP V AE D D+F G V Y C PGY L G
Sbjct: 2249 -------LNFHAFQLKKC----QPPPAVPQAEMLTED-DDFEIGDFVKYQCHPGYTLVGT 2296
Query: 336 ASMRC--TPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP-------------------V 374
+ C + Q + + PTCE + + + +G +L P
Sbjct: 2297 DILTCKLSSQLQFEGSLPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEP 2356
Query: 375 NLQLGAKVD-FVCDEGFQL-------KGSSASYCVLAGMESLWNSSVPVCEQI------- 419
N + VD F ++ F G S VL+G + ++ Q+
Sbjct: 2357 NYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTD 2416
Query: 420 ---------------FCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIG 464
+C + NG + G V+Y C P + ++G
Sbjct: 2417 HATSKKGFKIRYAAPYCSLTHPLKNGGILNRTAGA--VGSKVHYFCKP------GYRMVG 2468
Query: 465 ESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECR 524
S C +P G W S P C + C P+ + ++F + + + YEC
Sbjct: 2469 HSNATCRRNPLGMYQWDSLTPLCQAVS-CGIPE----SPGNGSFTGNEFTLDSKVVYECH 2523
Query: 525 PEY---YGRPFSITCLDNLVWSS--PKDVCKRKSCKTPPDPVNGMVHVITDI------QV 573
+ + + C ++ +WS+ CK +C P HVI + +
Sbjct: 2524 EGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVAC--PSIEAQLSEHVIWRLVSGSLNEY 2581
Query: 574 GSRINYSCTTGHRLIGHSSAECILSGNAAHWS--TKPPICQRIPCGLPPTIANGDFISTN 631
G+++ SC+ G+ L G C +G W+ + P C+ I CG NG+ I T
Sbjct: 2582 GAQVLLSCSPGYYLEGWRLLRCQANGT---WNIGDERPSCRVISCGSLSFPPNGNKIGTL 2638
Query: 632 RENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP 691
YG+ + CN G + LVG C +N G+WSG +C+ + +P
Sbjct: 2639 TV---YGATAIFTCNTG------YTLVGSHVRECLAN----GLWSGSETRCLAGHCGSPD 2685
Query: 692 NVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPP 750
+ NG + D FS + V ++C PGF + G C +KW + P C + C P
Sbjct: 2686 PIVNGHISGDG---FSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHP 2742
Query: 751 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDD 810
+ H + F+ V ++C GY L+G + +C G WS PTC V +C D
Sbjct: 2743 GNPAHG---FTNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSD 2799
Query: 811 ---FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCE 867
+ +G+ FP + + G + + C +GF L GSSA C+ G LW+ S+P C
Sbjct: 2800 PGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANG---LWDRSLPKCL 2856
Query: 868 QIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGN 927
I C P V N TG E+F +G V+Y+C RG S LIG T C D
Sbjct: 2857 AISCGHPGVPANAVLTG---ELFTYGAVVHYSC-----RG-SESLIGNDTRVCQEDSH-- 2905
Query: 928 GVWSSPAPRC-----GILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECR--PEYYGR 980
WS P C G G P H DF + L++ C + G
Sbjct: 2906 --WSGALPHCTGNNPGFCGDPGTPAH-------GSRLGDDFKTKSLLRFSCEMGHQLRGS 2956
Query: 981 PFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGH 1040
P TCL N WS + VC+ SC P P NGM+ I S + Y+C G++ G
Sbjct: 2957 P-ERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGL 3015
Query: 1041 SSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSR 1100
+ C +G W+ P C I CG P T+ANG T +F + V+Y+CN G
Sbjct: 3016 MTRHCTANGT---WTGTAPDCTIISCGDPGTLANGIQFGT---DFTFNKTVSYQCNPG-- 3067
Query: 1101 GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNE 1160
V E V +I CT + G W+ P C PP V+NG + + F
Sbjct: 3068 --YVMEAVTSATIRCTKD----GRWNPSKPVCKAVLCPQPPPVQNGTVEGSD---FRWGS 3118
Query: 1161 VVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPG 1219
+ + C G+ + + C+ W+ E+P C V C P G + +F+
Sbjct: 3119 SISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGK---SFTYK 3175
Query: 1220 QEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC---AVKSCDDFLGQLPH-GRVLFPLN 1275
EVF+ C+ + L G++ C G WS P C A +C D PH G
Sbjct: 3176 SEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPD--PGTPHFGIQNSSRG 3233
Query: 1276 LQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFC--PNPPAILNGRHT 1333
++G+ V F C +G+ ++GS+ C+ W+ C C P PA H
Sbjct: 3234 YEVGSTVFFRCRKGYHIQGSTTRTCL---ANLTWSGIQTECIPHACRQPETPA-----HA 3285
Query: 1334 GTPSGDIP-YGKEISYTCDPHPDRGMTFNLIGESTIR-CTSDPHGNGVWSSPAPRCE 1388
+ D+P +G + YTC P F L G S R C +D W+ +P C+
Sbjct: 3286 DVRAIDLPTFGYTLVYTCHP------GFFLAGGSEHRTCKADMK----WTGKSPVCK 3332
Score = 345 bits (885), Expect = 3e-94
Identities = 367/1371 (26%), Positives = 544/1371 (39%), Gaps = 205/1371 (14%)
Query: 552 KSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 611
++C PP NG + + +D VG +++ C G+ LIGH C G +W+ P C
Sbjct: 2086 QNCPDPPPFQNGYM-INSDYSVGQSVSFECYPGYILIGHPVLTC-QHGINRNWNYPFPRC 2143
Query: 612 QRIPCGLPPTIANGDFISTNRENFH---YGSVVTYRCNPGSGGRKVFELVGEPSIYCTSN 668
PCG T NG S + + + PG G F L+ ++
Sbjct: 2144 DA-PCGYNVTSQNGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAV----- 2197
Query: 669 DDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSL---FSLNEVVEFRCQPGFVMKGP 725
+D + +W GP + + G+ S N +L +S V + F G
Sbjct: 2198 NDYIAVWDGPDQN----------SPQLGVF-SGNTALETAYSSTNQVLLKFHSDFSNGGF 2246
Query: 726 RRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 785
+ A + CQPPP V AE D D+F G V Y C PGY L G
Sbjct: 2247 FVLNFHAFQL---------KKCQPPPAVPQAEMLTED-DDFEIGDFVKYQCHPGYTLVGT 2296
Query: 786 ASMRC--TPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP-------------------V 824
+ C + Q + + PTCE + + + +G +L P
Sbjct: 2297 DILTCKLSSQLQFEGSLPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEP 2356
Query: 825 NLQLGAKVD-FVCDEGFQL-------KGSSASYCVLAGMESLWNSSVPVCEQIF------ 870
N + VD F ++ F G S VL+G + ++ Q++
Sbjct: 2357 NYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTD 2416
Query: 871 ----------------CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIG 914
C + NG + G V+Y C P + ++G
Sbjct: 2417 HATSKKGFKIRYAAPYCSLTHPLKNGGILNRTAGAV--GSKVHYFCKP------GYRMVG 2468
Query: 915 ESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECR 974
S C +P G W S P C + C P+ + ++F + + + YEC
Sbjct: 2469 HSNATCRRNPLGMYQWDSLTPLCQAVS-CGIPE----SPGNGSFTGNEFTLDSKVVYECH 2523
Query: 975 PEYY---GRPFSITCLDNLVWSSP--KDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINY 1029
+ + + C ++ +WS+ CK +C P HVI + GS Y
Sbjct: 2524 EGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVAC--PSIEAQLSEHVIWRLVSGSLNEY 2581
Query: 1030 ------SCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRE 1083
SC+ G+ L G C +G T + + P C+ I CG NG+ I T
Sbjct: 2582 GAQVLLSCSPGYYLEGWRLLRCQANG-TWNIGDERPSCRVISCGSLSFPPNGNKIGTLTV 2640
Query: 1084 NFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 1143
YG+ + CN G + LVG C +N G+WSG +C+ + +P +
Sbjct: 2641 ---YGATAIFTCNTG------YTLVGSHVRECLAN----GLWSGSETRCLAGHCGSPDPI 2687
Query: 1144 ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPE 1202
NG + D FS + V ++C PGF + G C +KW + P C + C P
Sbjct: 2688 VNGHISGDG---FSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPITCGHPGN 2744
Query: 1203 ILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDD-- 1260
HG S F+ V ++C GY L+G + C G WS P C V +C D
Sbjct: 2745 PAHGFTNGSE---FNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPG 2801
Query: 1261 -FLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHI 1319
+ HG+ FP + + G + + C +GF L GSS C+ G LW+ S+P C I
Sbjct: 2802 FVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANG---LWDRSLPKCLAI 2858
Query: 1320 FCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGV 1379
C +P N TG YG + Y+C RG +LIG T C D H
Sbjct: 2859 SCGHPGVPANAVLTGEL---FTYGAVVHYSC-----RGSE-SLIGNDTRVCQEDSH---- 2905
Query: 1380 WSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGY-FGKMFSIS 1438
WS P C + G C P S + D +F + L + C G+ +
Sbjct: 2906 WSGALPHCTGN-NPGFCGDPGTPAHGSR---LGD-DFKTKSLLRFSCEMGHQLRGSPERT 2960
Query: 1439 CLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTC 1498
CL N WS ++ C SCG P P NGM+ + F S+V Y+C EG++ G + C
Sbjct: 2961 CLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHC 3020
Query: 1499 LVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLF 1558
+G TW AP C IISC P T++NG + T F V+YQC+ G +
Sbjct: 3021 TANG---TWTGTAPDCTIISCGDPGTLANGIQFG---TDFTFNKTVSYQCNPG----YVM 3070
Query: 1559 ELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFR 1618
E V +I CT KD G W+ P C + P V+N V G S F I +
Sbjct: 3071 EAVTSATIRCT-KD---GRWNPSKPVCKAVLCPQPPPVQNG-TVEG--SDFRWGSSISYS 3123
Query: 1619 CQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYS 1678
C G+ + S + C+ G W ++P C V P I E LS + +F+ EVF+
Sbjct: 3124 CMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGI-PAEGRLSGK-SFTYKSEVFFQ 3181
Query: 1679 CEPSYDLRGAASLHCTPQGDWSPEAPRC---TVKSCDDFLGQLPH-GRVLLPLNLQLGAK 1734
C+ + L G++ C G WS P C +C D PH G ++G+
Sbjct: 3182 CKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPD--PGTPHFGIQNSSRGYEVGST 3239
Query: 1735 VSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFC--PNPPAILNGRHTGTPFGD 1792
V F C +G+ ++G + C+ W+ C C P PA H D
Sbjct: 3240 VFFRCRKGYHIQGSTTRTCL---ANLTWSGIQTECIPHACRQPETPA-----HADVRAID 3291
Query: 1793 IP-YGKEISYACDTHPDRGMTFNLIGESSIR-CTSDPQGNGVWSSPAPRCE 1841
+P +G + Y C HP F L G S R C +D + W+ +P C+
Sbjct: 3292 LPTFGYTLVYTC--HPG----FFLAGGSEHRTCKADMK----WTGKSPVCK 3332
Score = 315 bits (806), Expect = 4e-85
Identities = 262/902 (29%), Positives = 388/902 (43%), Gaps = 107/902 (11%)
Query: 62 EFPIGTYLNYECRPGY---SGRPFSIICLKNSVWT--GAKDRCRRKSCRNPPDPVNGMVH 116
EF + + + YEC G+ S + + +C ++ +W+ G C+ +C P H
Sbjct: 2511 EFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVAC--PSIEAQLSEH 2568
Query: 117 VIKGI------QFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPP 170
VI + ++G+Q+ SC+ GY L G C +G I D E P C I CG
Sbjct: 2569 VIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGD-ERPSCRVISCGSLS 2627
Query: 171 TITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAP 230
NG+ I T YG+ + CN G + LVG C +N G+WSG
Sbjct: 2628 FPPNGNKIGTLTV---YGATAIFTCNTG------YTLVGSHVRECLAN----GLWSGSET 2674
Query: 231 QCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPEL 290
+C+ + +P + NG + D FS + V ++C PGF + G C +KW +
Sbjct: 2675 RCLAGHCGSPDPIVNGHISGDG---FSYRDTVVYQCNPGFRLVGTSVRICLQDHKWSGQT 2731
Query: 291 PSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPA 349
P C + C P + H + F+ V ++C GY L+G + +C G WS
Sbjct: 2732 PVCVPITCGHPGNPAHGFTNGSE---FNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSP 2788
Query: 350 APTCEVKSCDD---FMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGME 406
PTC V +C D + +G+ FP + + G + + C +GF L GSSA C+ G
Sbjct: 2789 LPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANG-- 2846
Query: 407 SLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGES 466
LW+ S+P C I C P V N TG E+F +G V+Y+C RG+ LIG
Sbjct: 2847 -LWDRSLPKCLAISCGHPGVPANAVLTG---ELFTYGAVVHYSC-----RGSE-SLIGND 2896
Query: 467 TIRCTSDPQGNGVWSSPAPRC-----GILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKY 521
T C D WS P C G G P H DF + L++
Sbjct: 2897 TRVCQEDSH----WSGALPHCTGNNPGFCGDPGTPAH-------GSRLGDDFKTKSLLRF 2945
Query: 522 ECRPEYY--GRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINY 579
C + G P TCL N WS + VC+ SC P P NGM+ I S + Y
Sbjct: 2946 SCEMGHQLRGSP-ERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIY 3004
Query: 580 SCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGS 639
+C G++ G + C +G W+ P C I CG P T+ANG T +F +
Sbjct: 3005 ACWEGYKTSGLMTRHCTANGT---WTGTAPDCTIISCGDPGTLANGIQFGT---DFTFNK 3058
Query: 640 VVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILV 699
V+Y+CNPG V E V +I CT + G W+ P C PP V+NG +
Sbjct: 3059 TVSYQCNPG----YVMEAVTSATIRCTKD----GRWNPSKPVCKAVLCPQPPPVQNGTVE 3110
Query: 700 SDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERT 759
+ F + + C G+ + + C+ W+ E+P C V P + AE
Sbjct: 3111 GSD---FRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPVFCGDPGI-PAEGR 3166
Query: 760 QRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC---EVKSCDDFMGQLL 816
K +F+ EVF+ C+ + L G++ C G WS PTC +C D G
Sbjct: 3167 LSGK-SFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPD-PGTPH 3224
Query: 817 NGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPV 876
G ++G+ V F C +G+ ++GS+ C LA + W+ C C P
Sbjct: 3225 FGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTC-LANL--TWSGIQTECIPHACRQPET 3281
Query: 877 IPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIR-CTSDPQGNGVWSSPAP 935
+ + +++ FG + YTC P F L G S R C +D + W+ +P
Sbjct: 3282 PAHA--DVRAIDLPTFGYTLVYTCHP------GFFLAGGSEHRTCKADMK----WTGKSP 3329
Query: 936 RC 937
C
Sbjct: 3330 VC 3331
Score = 275 bits (702), Expect = 4e-73
Identities = 262/970 (27%), Positives = 360/970 (37%), Gaps = 135/970 (13%)
Query: 1066 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1125
C L + NG + NR GS V Y C G R +VG + C N + W
Sbjct: 2433 CSLTHPLKNGGIL--NRTAGAVGSKVHYFCKPGYR------MVGHSNATCRRNPLGMYQW 2484
Query: 1126 SGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVK--CQAL 1183
P C + P + NG + F+L+ V + C GF ++ ++ CQ
Sbjct: 2485 DSLTPLCQAVSCGIPESPGNGSFTGNE---FTLDSKVVYECHEGFKLESSQQATAVCQED 2541
Query: 1184 NKW--EPELPSCSRVCQPPPEILHGEHTPSHQDNFSP---GQEVFYSCEPGYDLRGAASL 1238
W + + P+C V P E EH + S G +V SC PGY L G L
Sbjct: 2542 GLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYLEGWRLL 2601
Query: 1239 HCTPQGDWS--PEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSS 1296
C G W+ E P C V SC L P+G + L + GA F C+ G+ L GS
Sbjct: 2602 RCQANGTWNIGDERPSCRVISCGS-LSFPPNGNKIGTLTVY-GATAIFTCNTGYTLVGSH 2659
Query: 1297 VSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDR 1356
V C+ G LW+ S C C +P I+NG +G Y + Y C+P
Sbjct: 2660 VRECLANG---LWSGSETRCLAGHCGSPDPIVNGHISGD---GFSYRDTVVYQCNPG--- 2710
Query: 1357 GMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEF 1416
F L+G S C D WS P C + + GH P F N EF
Sbjct: 2711 ---FRLVGTSVRICLQDHK----WSGQTPVC-VPITCGHPGNPAH-GFT------NGSEF 2755
Query: 1417 PVGTSLNYECRPGYFGKMFS-ISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVH----IN 1471
+ +N+ C GY + S C N WSS CR +C P N + H
Sbjct: 2756 NLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRHGQQNFP 2815
Query: 1472 TDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFY 1531
++G ++ Y C +GF L+GS + TC+ +G WD+ P C ISC P +N
Sbjct: 2816 ESFEYGMSILYHCKKGFYLLGSSALTCMANG---LWDRSLPKCLAISCGHPGVPANAVLT 2872
Query: 1532 SNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKC 1591
F G VV Y C L+G + C WS P C N
Sbjct: 2873 GE---LFTYGAVVHYSCRGSES------LIGNDTRVCQEDSH----WSGALPHCTGNNPG 2919
Query: 1592 TAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-C 1650
+ F ++RF C+ G + GS C NG W P C V C
Sbjct: 2920 FCGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGLQPVCEAVSC 2979
Query: 1651 QPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKS 1710
P +G S FS V Y+C Y G + HCT G W+ AP CT+ S
Sbjct: 2980 GNPGTPTNGMIVSSDGILFS--SSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTIIS 3037
Query: 1711 CDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSAS--HCVLAGMKALWNSSVPV 1768
C D G L +G + + VS+ C+ G+ ++ +++ C G WN S PV
Sbjct: 3038 CGD-PGTLANG-IQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGR---WNPSKPV 3092
Query: 1769 CEQIFCPNPPAILNGRHTGTPF-------------------------------GDIPY-- 1795
C+ + CP PP + NG G+ F G+IP
Sbjct: 3093 CKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCL 3152
Query: 1796 ----------------GKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPR 1839
GK +Y + F L+G S C +D G WS P
Sbjct: 3153 PVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQAD----GTWSGIQPT 3208
Query: 1840 CELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQ 1899
C CP P G I Y G T+ + C GY + G C WS
Sbjct: 3209 CIDPAHNTCPDPGTPHFG--IQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCLANLTWSG 3266
Query: 1900 LDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLE-GSPWSQCQADDRW 1958
+ C C P ++ + +G + C G+ L GS C+AD +W
Sbjct: 3267 IQTECIPHACRQP--ETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKADMKW 3324
Query: 1959 DPPLAKCTSR 1968
C S+
Sbjct: 3325 TGKSPVCKSK 3334
Score = 208 bits (529), Expect = 5e-53
Identities = 171/643 (26%), Positives = 261/643 (40%), Gaps = 79/643 (12%)
Query: 58 TDEFEFPIGTYLNYECRPGYSGRPFS-IICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVH 116
T+ EF + +N+ C GY + S C N W+ CR +C +P N + H
Sbjct: 2750 TNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVVNCSDPGFVENAIRH 2809
Query: 117 ----VIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTI 172
+ ++G I Y C KG+ L+GSS+ TC+ +G +WD P C I CG P
Sbjct: 2810 GQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANG---LWDRSLPKCLAISCGHPGVP 2866
Query: 173 TNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 232
N E F YG+VV Y C R L+G + C + WSG P C
Sbjct: 2867 ANAVLTG---ELFTYGAVVHYSC------RGSESLIGNDTRVCQEDSH----WSGALPHC 2913
Query: 233 I--IPNKCTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPE 289
P C P +G + D+ F ++ F C+ G ++G C W
Sbjct: 2914 TGNNPGFCGDPGTPAHGSRLGDD---FKTKSLLRFSCEMGHQLRGSPERTCLLNGSWSGL 2970
Query: 290 LPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSP 348
P C V C P + D FS V Y+C GY G + CT G W+
Sbjct: 2971 QPVCEAVSCGNPGTPTNGMIVSSDGILFS--SSVIYACWEGYKTSGLMTRHCTANGTWTG 3028
Query: 349 AAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESL 408
AP C + SC D G L NG + F + V + C+ G+ ++ + S + +
Sbjct: 3029 TAPDCTIISCGD-PGTLANG-IQFGTDFTFNKTVSYQCNPGYVME-AVTSATIRCTKDGR 3085
Query: 409 WNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTI 468
WN S PVC+ + CP PP + NG G F +G +++Y+C + L + +
Sbjct: 3086 WNPSKPVCKAVLCPQPPPVQNGTVEGSD---FRWGSSISYSC------MDGYQLSHSAIL 3136
Query: 469 RCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY 528
C +G GVW P+C + C P + + + F + + ++C+
Sbjct: 3137 SC----EGRGVWKGEIPQC-LPVFCGDPG----IPAEGRLSGKSFTYKSEVFFQCK---- 3183
Query: 529 GRPFSI------TCLDNLVWSSPKDVC---KRKSCKTPPDPVNGMVHVITDIQVGSRINY 579
PF + C + WS + C +C P P G+ + +VGS + +
Sbjct: 3184 -SPFILVGSSRRVCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFF 3242
Query: 580 SCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGS 639
C G+ + G ++ C+ + WS C C P T A+ D + + F Y
Sbjct: 3243 RCRKGYHIQGSTTRTCLAN---LTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGY-- 3297
Query: 640 VVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 682
+ Y C+PG F L G S + T D W+G +P C
Sbjct: 3298 TLVYTCHPG------FFLAG-GSEHRTCKADMK--WTGKSPVC 3331
Score = 96.7 bits (239), Expect = 2e-19
Identities = 380/1820 (20%), Positives = 598/1820 (32%), Gaps = 434/1820 (23%)
Query: 88 KNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCII 147
KNSV + C +P P NG + G+ +++SC Y L GS S TC
Sbjct: 333 KNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQR 392
Query: 148 SGDTVI-WDNETPICDRIPCGLPPTITNGDFISTN-----RENFHYGSVVTYRCNPGSGG 201
+T+ W + PIC CG +G S N +N H V+T +P
Sbjct: 393 VTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVIT-TTDPDKVI 451
Query: 202 RKVFE-----------LVGEPS--------------------IYCTSN--------DDQV 222
+ FE VG+ I SN DD +
Sbjct: 452 KLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSI 511
Query: 223 GIWSGPAP-QCIIPNKCTPPNVENGILVSDNR--SLFSLNEVVEFRCQPGFVMKGPRRVK 279
G A Q I C P GI R S F + + F C F + G R +
Sbjct: 512 GSPGFKAVYQEIEKGGCGDP----GIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVIT 567
Query: 280 CQALNKWEPELP----SCSRVCQPPPDVLHAERTQRDKDN---------FSPGQEVF--- 323
CQ N+W P SC ++ + + N PG +
Sbjct: 568 CQQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIF 627
Query: 324 --YSCEPGYDLRGAAS---------------------------MRCTPQGDWSPAA---- 350
+ EP +D +R Q D S
Sbjct: 628 NDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRGFN 687
Query: 351 ---PTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGF-QLKGSSASYCVLAGME 406
T C D G +NGR F LG+ V F CD+GF + +GS + C+L
Sbjct: 688 ITYTTFGQNECHD-PGIPINGR-RFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGN 745
Query: 407 SLWNSSVPVCE-----QIFCPSPPVIPNG--------RHTGKPLEVFPFGKTVNYTCDPH 453
+W+S+VP CE + S ++P G H +E P G ++ T D
Sbjct: 746 VVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHCEWIIEAKP-GHSIKITFDRF 804
Query: 454 PDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFL----FAKLKTQTN 509
+ T+ P +S +P G QAP + F L T+
Sbjct: 805 QTE------VNYDTLEVRDGP------ASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTD 852
Query: 510 ASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVIT 569
S IG + YE S+T + SC P PVNG H
Sbjct: 853 NSRSSIGFLIHYE----------SVT-------------LESDSCLDPGIPVNGHRHG-G 888
Query: 570 DIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFIS 629
D + S + +SC G+ L S E ++ W+ P C + CG +G +S
Sbjct: 889 DFGIRSTVTFSCDPGYTL---SDDEPLVCERNHQWNHALPSCDAL-CGGYIQGKSGTVLS 944
Query: 630 TNRENFHYGSV---VTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPN 686
+F+ S+ T + G G + +F S + + G +S P + +
Sbjct: 945 PGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEPVAR--LTG 1002
Query: 687 KCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 746
P ++ G+ + F Q F+ + + E +L C
Sbjct: 1003 SVLPHTIKAGLFGN-------------FTAQLRFISDFSISYEGFNITFSEYDLEPCDDP 1049
Query: 747 CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGD--WSPAAPTCE 804
P ++R +F G + +SC GY L GA + C G WS P C
Sbjct: 1050 GVP-------AFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCV 1102
Query: 805 VK---SCDDFMGQLL----------NGRVLFPVNLQLGAKV-----DFVCDEGFQLK--- 843
+ S G LL N ++ + + G + F EG LK
Sbjct: 1103 AECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKVYD 1162
Query: 844 GSSASYCVL--------------AGMESLW---NSSVPVCEQIF-----------CPSPP 875
G +S L + LW N++ +Q F C P
Sbjct: 1163 GKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCEDPG 1222
Query: 876 VIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAP 935
IPN + + F V Y+C+P + + G +T+ C S + VW P P
Sbjct: 1223 -IPNYGYRIRDEGHFT-DTVVLYSCNP------GYAMHGSNTLTCLSGDR--RVWDKPLP 1272
Query: 936 RCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNL----- 990
C + C H A + + +P C P L +
Sbjct: 1273 SC--IAECGGQIH---AATSGRILSPGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTE 1327
Query: 991 -------VWSSPKD---VCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGH 1040
VW P D + K S P+ ++ + +T +Q S S
Sbjct: 1328 MAHDILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLT-LQFDSDFFIS---------- 1376
Query: 1041 SSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSR 1100
SG + +ST C P NG +RE G VT++C+ G
Sbjct: 1377 ------KSGFSIQFSTS----IAATCNDPGMPQNGTRYGDSRE---AGDTVTFQCDPG-- 1421
Query: 1101 GRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIP--NKCTPPNVENGILVSDNRSLFSL 1158
++L G+ I C +++ W P CI T P G+++S
Sbjct: 1422 ----YQLQGQAKITCVQLNNRF-FWQPDPPTCIAACGGNLTGP---AGVILS-------- 1465
Query: 1159 NEVVEFRCQPGFVMKGPRRVKCQALNKWEPE----LPSCSRVCQPPPEILH---GEHT-- 1209
P + P +C K P+ L S +P + LH GE +
Sbjct: 1466 ---------PNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNS 1516
Query: 1210 ---PSHQDNFSP------GQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDD 1260
S+Q + +P G +F + R AS+ + E PR ++C D
Sbjct: 1517 PLIGSYQGSQAPERIESSGNSLFLA------FRSDASVGLSGFAIEFKEKPR---EACFD 1567
Query: 1261 FLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVL-VGMRSLWNNSVPVCEHI 1319
G + +G + +LG+ +++ CD G+++ S CV+ + W+ +P C
Sbjct: 1568 -PGNIMNG-TRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSC--- 1622
Query: 1320 FCPNPPAILNGRHTGTP----SGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPH 1375
N P G++TG+ S + P+ C F + G+ T+
Sbjct: 1623 ---NAPC--GGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALND 1677
Query: 1376 GNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMF 1435
++ + L + E P A+ + L + + G + F
Sbjct: 1678 LAELFDGTHAQARLLSSLSGSHSGETLPLATSNQIL----------LRFSAKSGASARGF 1727
Query: 1436 SISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPS 1495
+ V+ +V C PEP G I ++ GS V + CN G+ L GS +
Sbjct: 1728 ------HFVYQAV-PRTSDTQCSSVPEPRYGR-RIGSEFSAGSIVRFECNPGYLLQGSTA 1779
Query: 1496 TTCLVSGNNVT-WDKKAPICEIISCEPPPTISNGDF--------YSNN------------ 1534
C N + W+ P C ++ C T G Y NN
Sbjct: 1780 LHCQSVPNALAQWNDTIPSC-VVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEG 1838
Query: 1535 -----------------RTSFHNGTVVTYQCHTGPDGEQLFELVGERS----IYCTSKDD 1573
H+G VT G + L+ S ++ S
Sbjct: 1839 SGIQIQVISFATEQNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDIS 1898
Query: 1574 QVGVWSSPPPRCISTNKCTAPEV-ENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQ 1632
+ + C P + N+I++ G+R + + +++ F+C+PG+ + G +
Sbjct: 1899 VAAAGFHLEYKTVGLAACQEPALPSNSIKI-GDR--YMVNDVLSFQCEPGYTLQGRSHIS 1955
Query: 1633 CQ--TNGRWGPKLPHCSRVC 1650
C T RW P C C
Sbjct: 1956 CMPGTVRRWNYPSPLCIATC 1975
Score = 61.2 bits (147), Expect = 1e-08
Identities = 109/468 (23%), Positives = 165/468 (35%), Gaps = 107/468 (22%)
Query: 1456 SCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVS-GNNVTWDKKAPIC 1514
+CG P E G++H T G + YSC G+ L G TC+VS GN +WD AP C
Sbjct: 144 TCGNPGEILKGVLH-GTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFC 202
Query: 1515 EIISC------EPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQL------FELVG 1562
+IS+ F S + N T+ P G+ + F+L
Sbjct: 203 RAEGACGGTLRGTSSSISSPHFPS----EYENNADCTWTILAEP-GDTIALVFTDFQLEE 257
Query: 1563 ERSIYCTSKDDQVGVW----SSPPPRCISTNKCTAPEVENA-IRVPGNRSFFTLTEIIRF 1617
S + +W + P P S N ++ R G + F + + I
Sbjct: 258 GYDFLEISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIEL 317
Query: 1618 RCQPGFVMV----GSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQ 1673
+ + G M+ GSH + G G L S +C P +G S D G
Sbjct: 318 KSR-GVKMLPSKDGSHKNSVLSQG--GVAL--VSDMCPDPGIPENGRRAGS--DFSRVGA 370
Query: 1674 EVFYSCEPSYDLRGAASLHCTPQGD----WSPEAPRCTVKSCDDFLGQLPHGRVLLP--- 1726
V +SCE +Y L+G+ S+ C + WS P C ++C L + P G + P
Sbjct: 371 NVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNL-RGPSGVITSPNYP 429
Query: 1727 ----------------------------LNLQLGAKVSFVCDEG---------FRLKGRS 1749
L+ G V D G + L G S
Sbjct: 430 VQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSS 489
Query: 1750 ASHCVLAGMKALW-------NSSVPVCEQIF-------CPNPPAILNGRHTGTPFGDIPY 1795
+++ +W + P + ++ C +P G+ TG+ F +
Sbjct: 490 VPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSF---LH 546
Query: 1796 GKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELS 1843
G +++ C F L+GE I C Q N WS P C S
Sbjct: 547 GDTLTFECPA------AFELVGERVITC----QQNNQWSGNKPSCVFS 584
Score = 58.9 bits (141), Expect = 5e-08
Identities = 104/474 (21%), Positives = 161/474 (33%), Gaps = 113/474 (23%)
Query: 547 DVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS-GNAAHWS 605
+V +C P + + G++H T +G +I YSC G+ L GH+ CI+S GN A W
Sbjct: 138 EVLPSHTCGNPGEILKGVLHG-TRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWD 196
Query: 606 TKPPICQRIPC------GLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVG 659
P C+ G +I++ F S N T PG VF
Sbjct: 197 FPAPFCRAEGACGGTLRGTSSSISSPHFPSEYENN--ADCTWTILAEPGDTIALVF---- 250
Query: 660 EPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPG 719
D + I AP + T N+ + ++ S N R + G
Sbjct: 251 -TDFQLEEGYDFLEISGTEAPSIWL----TGMNLPSPVISSKNWLRLHFTSDSNHR-RKG 304
Query: 720 FVMKGPRRVKCQALNKWEPELPS--------------CSRVCQPPPDVLHAERTQRDKDN 765
F + + + ++ LPS + V PD E +R +
Sbjct: 305 FNAQFQVKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSD 364
Query: 766 FS-PGQEVFYSCEPGYDLRGAASMRCTPQGD----WSPAAPTCEVKSCDDFMGQLLNG-- 818
FS G V +SCE Y L+G+ S+ C + WS P C ++C G L G
Sbjct: 365 FSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTC----GSNLRGPS 420
Query: 819 ----RVLFPVNLQLGAKV------------------DFVCDEGFQ--------------- 841
+PV + A +F + G+
Sbjct: 421 GVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRS 480
Query: 842 ----LKGSSASYCVLAGMESLW-------NSSVPVCEQIF-------CPSPPVIPNGRHT 883
L GSS +++ +W + P + ++ C P + G+ T
Sbjct: 481 VLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRT 540
Query: 884 GKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 937
G F G + + C +F+L+GE I C Q N WS P C
Sbjct: 541 GSS---FLHGDTLTFECP------AAFELVGERVITC----QQNNQWSGNKPSC 581
Score = 58.9 bits (141), Expect = 5e-08
Identities = 104/468 (22%), Positives = 160/468 (34%), Gaps = 113/468 (24%)
Query: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIIS-GDTVIWDNETPIC 161
+C NP + + G++H + G +I+YSC GY L G + TCI+S G+ WD P C
Sbjct: 144 TCGNPGEILKGVLHGTR-FNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFC 202
Query: 162 DRIPC------GLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYC 215
G +I++ F S N T PG VF
Sbjct: 203 RAEGACGGTLRGTSSSISSPHFPSEYENN--ADCTWTILAEPGDTIALVF-----TDFQL 255
Query: 216 TSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP 275
D + I AP + T N+ + ++ S N R + GF +
Sbjct: 256 EEGYDFLEISGTEAPSIWL----TGMNLPSPVISSKNWLRLHFTSDSNHR-RKGFNAQFQ 310
Query: 276 RRVKCQALNKWEPELPS--------------CSRVCQPPPDVLHAERTQRDKDNFS-PGQ 320
+ + ++ LPS + V PD E +R +FS G
Sbjct: 311 VKKAIELKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGA 370
Query: 321 EVFYSCEPGYDLRGAASMRCTPQGD----WSPAAPTCEVKSCDDFMGQLLNG------RV 370
V +SCE Y L+G+ S+ C + WS P C ++C G L G
Sbjct: 371 NVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICRARTC----GSNLRGPSGVITSP 426
Query: 371 LFPVNLQLGAKV------------------DFVCDEGFQ-------------------LK 393
+PV + A +F + G+ L
Sbjct: 427 NYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLT 486
Query: 394 GSSASYCVLAGMESLW-------NSSVPVCEQIF-------CPSPPVIPNGRHTGKPLEV 439
GSS +++ +W + P + ++ C P + G+ TG
Sbjct: 487 GSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSS--- 543
Query: 440 FPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 487
F G T+ + C +F+L+GE I C Q N WS P C
Sbjct: 544 FLHGDTLTFECP------AAFELVGERVITC----QQNNQWSGNKPSC 581
Score = 57.4 bits (137), Expect = 1e-07
Identities = 173/825 (20%), Positives = 255/825 (30%), Gaps = 203/825 (24%)
Query: 1282 VSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIP 1341
V + C+ G+ + GS+ C L G R +W+ +P C A +GR +P P
Sbjct: 1241 VLYSCNPGYAMHGSNTLTC-LSGDRRVWDKPLPSCIAECGGQIHAATSGRIL-SPGYPAP 1298
Query: 1342 YGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGN-GVWSSPAPRCELSVRAGHCKTPE 1400
Y + T D G T +L + T H VW P L PE
Sbjct: 1299 YDNNLHCTWIIEADPGKTISL--HFIVFDTEMAHDILKVWDGPVDSDILLKEWSGSALPE 1356
Query: 1401 QF--PFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRRKSCG 1458
F S T+ D +F + S F FS S +C
Sbjct: 1357 DIHSTFNSLTLQF-DSDFFISKS--------GFSIQFSTSIAA--------------TCN 1393
Query: 1459 PPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIIS 1518
P P NG + G TV + C+ G++L G TC+ N W P C I +
Sbjct: 1394 DPGMPQNG-TRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTC-IAA 1451
Query: 1519 CEPPPTISNGDFYSNNRTS-FHNGTVVTYQCHTGPD------------------------ 1553
C T G S N + G ++ PD
Sbjct: 1452 CGGNLTGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEG 1511
Query: 1554 ------------GEQLFELV---GERSIYCTSKDDQVGVWS-----SPPPRCISTNKCTA 1593
G Q E + G D VG+ PR C
Sbjct: 1512 EDSNSPLIGSYQGSQAPERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPR----EACFD 1567
Query: 1594 P-EVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNG----RWGPKLPHCSR 1648
P + N RV + F L I ++C G+ ++ ++ C W LP C+
Sbjct: 1568 PGNIMNGTRVGTD---FKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNA 1624
Query: 1649 VCQPPPEILHGEHTLS--------HQDNFSPGQEVFYSCE--PSYDLRGAASLHCTPQGD 1698
C G++T S + N++ GQ YS + + G + T D
Sbjct: 1625 PCG-------GQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALND 1677
Query: 1699 WSP--EAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLA 1756
+ + + G H LPL + F G +G H V
Sbjct: 1678 LAELFDGTHAQARLLSSLSGS--HSGETLPLATSNQILLRFSAKSGASARG---FHFVY- 1731
Query: 1757 GMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLI 1816
+VP C + P GR G+ F G + + C+ + L
Sbjct: 1732 -------QAVPRTSDTQCSSVPEPRYGRRIGSEFSA---GSIVRFECNPG------YLLQ 1775
Query: 1817 GESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISY- 1875
G +++ C S P W+ P C VP + G++ ++ PG Y
Sbjct: 1776 GSTALHCQSVPNALAQWNDTIPSCV--VPCS---------GNFTQRRGTILSPGYPEPYG 1824
Query: 1876 ---------ICDPGYLLVGKGFIFCTDQGIWSQLD-HYCKEVNC---------SFPLFMN 1916
I G + + F T+Q W L+ H +V + P +N
Sbjct: 1825 NNLNCIWKIIVTEGSGIQIQVISFATEQN-WDSLEIHDGGDVTAPRLGSFSGTTVPALLN 1883
Query: 1917 GISKEL-----------------EMKKV--------------------YHYGDYVTLKCE 1939
S +L E K V Y D ++ +CE
Sbjct: 1884 STSNQLYLHFQSDISVAAAGFHLEYKTVGLAACQEPALPSNSIKIGDRYMVNDVLSFQCE 1943
Query: 1940 DGYTLEGSPWSQCQADD--RWDPPLAKCTSRTHDALIVGTLSGTI 1982
GYTL+G C RW+ P C + L TL G I
Sbjct: 1944 PGYTLQGRSHISCMPGTVRRWNYPSPLCIATCGGTL--STLGGVI 1986
Score = 57.0 bits (136), Expect = 2e-07
Identities = 106/443 (23%), Positives = 150/443 (33%), Gaps = 93/443 (20%)
Query: 1457 CGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCL-VSGNNVTWDKKAPICE 1515
C P P NG + ++ G+ V +SC + + L GS S TC V+ W PIC
Sbjct: 349 CPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICR 408
Query: 1516 IISCE-----PPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPD-----GEQLFELVGERS 1565
+C P I++ ++ + H V+T T PD + FEL
Sbjct: 409 ARTCGSNLRGPSGVITSPNYPVQYEDNAHCVWVITT---TDPDKVIKLAFEEFELERGYD 465
Query: 1566 IYCTSKDDQVG---------VWSSPPPRCISTN------------------KCTAPEVEN 1598
+VG SS P +S + K E+E
Sbjct: 466 TLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEK 525
Query: 1599 A------IRVPGNR--SFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVC 1650
I G R S F + + F C F +VG + CQ N +W P C C
Sbjct: 526 GGCGDPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQWSGNKPSCVFSC 585
Query: 1651 QPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDW---SPEAPRCT 1707
NF+ + S P+Y +++C W S R
Sbjct: 586 F---------------FNFTASSGIILS--PNYPEEYGNNMNCV----WLIISEPGSRIH 624
Query: 1708 VKSCD-------DFLGQLPHG-RVLLPLNLQLGAKV-SFVCDEGFRLKGRSASHCVLAGM 1758
+ D DFL G + L G +V S + G ++ S G
Sbjct: 625 LIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGR 684
Query: 1759 KALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGE 1818
+N + Q C +P +NGR G F G +S+ CD + G
Sbjct: 685 G--FNITYTTFGQNECHDPGIPINGRRFGDRF---LLGSSVSFHCDDGFVKTQ-----GS 734
Query: 1819 SSIRCTSDPQGNGVWSSPAPRCE 1841
SI C GN VWSS PRCE
Sbjct: 735 ESITCILQ-DGNVVWSSTVPRCE 756
Score = 52.0 bits (123), Expect = 6e-06
Identities = 209/1084 (19%), Positives = 343/1084 (31%), Gaps = 280/1084 (25%)
Query: 1140 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALN----KWEPELP---- 1191
P + G+L + + F++ + + + C PG++++G + C W+ P
Sbjct: 148 PGEILKGVL---HGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRA 204
Query: 1192 --SCSRVCQPPPEILHGEHTPSHQDNFS---------PGQEVF-----YSCEPGYDLRGA 1235
+C + + H PS +N + PG + + E GYD
Sbjct: 205 EGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEI 264
Query: 1236 ASLHCTPQGDWSPEAPRCAVKSCD----DFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFR 1291
+ P + S + F H R F Q+ +
Sbjct: 265 SGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSRGVKM 324
Query: 1292 LKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCD 1351
L SH S+ + CP+P NGR G+ + G + ++C+
Sbjct: 325 LPSKDGSH-----KNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRV--GANVQFSCE 377
Query: 1352 PHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPI 1411
+ + L G +I C WS P C + + P SP P+
Sbjct: 378 DN------YVLQGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGV-ITSPNYPV 430
Query: 1412 N-------------------------DFEFPVGTSLNYECRPGYFGKMFS---------- 1436
+FE G G G S
Sbjct: 431 QYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSV 490
Query: 1437 ---ISCLENLVW--------------SSVEDNCRRKSCGPPPEPFNGMVHINTDTQF--G 1477
I + N +W +V + CG P P G T + F G
Sbjct: 491 PDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGK---RTGSSFLHG 547
Query: 1478 STVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTS 1537
T+ + C F L+G TC N W P C + SC T S+G S N
Sbjct: 548 DTLTFECPAAFELVGERVITCQ---QNNQWSGNKPSC-VFSCFFNFTASSGIILSPNYPE 603
Query: 1538 FHNGTVVTYQCHTGPDGEQLFELVGERSI-----YCTSKDDQV------GVWSSP--PPR 1584
+ + G ++ + + + + KDD + G +S P +
Sbjct: 604 EYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQ 663
Query: 1585 CIST----------------------------NKCTAPEVENAIRVPGNRSFFTLTEIIR 1616
S+ N+C P + R G+R F L +
Sbjct: 664 LASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGIPINGRRFGDR--FLLGSSVS 721
Query: 1617 FRCQPGFVMV-GSHTVQC---QTNGRWGPKLPHC-----------SRVCQPP------PE 1655
F C GFV GS ++ C N W +P C S V PP +
Sbjct: 722 FHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKD 781
Query: 1656 ILHGEHTLSHQDNFSPGQEVF-----YSCEPSYD---LRGAASLHCTPQGDW-SPEAPRC 1706
LH E + + PG + + E +YD +R + G++ +AP+
Sbjct: 782 SLHCEWIIEAK----PGHSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQF 837
Query: 1707 ------------TVKSCDDFLGQLPHGRVL-----------LPLN-------LQLGAKVS 1736
T + +G L H + +P+N + + V+
Sbjct: 838 LISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVT 897
Query: 1737 FVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDI-PY 1795
F CD G+ L S ++ WN ++P C+ + C +G F D P
Sbjct: 898 FSCDPGYTL---SDDEPLVCERNHQWNHALPSCDAL-CGGYIQGKSGTVLSPGFPDFYPN 953
Query: 1796 GKEISYACDTHPDRGM-----TFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPH 1850
++ + +G+ TF+L ++ +G +S P R SV PH
Sbjct: 954 SLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITE---DGSFSEPVARLTGSV---LPH 1007
Query: 1851 PPKIQNGHYIGGHVSL-YLPGMTISYICDPGYLLVGKGFIF--CTDQGIWSQLDHYCKEV 1907
I+ G + L ++ +ISY G+ + + C D G+
Sbjct: 1008 T--IKAGLFGNFTAQLRFISDFSISY---EGFNITFSEYDLEPCDDPGV----------- 1051
Query: 1908 NCSFPLFMNGISKELEMKKVYHYG--DYVTLKCEDGYTLEGSPWSQCQADDR--WDPPLA 1963
P F I +H+G D +T C GY LEG+ C R W PL
Sbjct: 1052 ----PAFSRRIG--------FHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLP 1099
Query: 1964 KCTSRTHDALIVGTLSGTIFFILLIIFLSWIILKHRKGNNAHENPKEVAIHLHSQGGSSV 2023
+C + A + G GT +L +N ++N E + ++ G +
Sbjct: 1100 RCVAEC-GASVKGN-EGT-------------LLSPNFPSN-YDNNHECIYKIETEAGKGI 1143
Query: 2024 HPRT 2027
H RT
Sbjct: 1144 HLRT 1147
Score = 47.8 bits (112), Expect = 1e-04
Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 2/67 (2%)
Query: 997 DVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS-GNTAHWS 1055
+V +C P + + G++H T +G +I YSC G+ L GH+ CI+S GN A W
Sbjct: 138 EVLPSHTCGNPGEILKGVLHG-TRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWD 196
Query: 1056 TKPPICQ 1062
P C+
Sbjct: 197 FPAPFCR 203
Score = 39.3 bits (90), Expect = 0.040
Identities = 25/64 (39%), Positives = 28/64 (43%), Gaps = 7/64 (10%)
Query: 1194 SRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQ----GDWSPE 1249
S C P EIL G H F+ G ++ YSC PGY L G A L C W
Sbjct: 142 SHTCGNPGEILKGV---LHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFP 198
Query: 1250 APRC 1253
AP C
Sbjct: 199 APFC 202
Score = 38.1 bits (87), Expect = 0.089
Identities = 24/64 (37%), Positives = 28/64 (43%), Gaps = 7/64 (10%)
Query: 1647 SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQ----GDWSPE 1702
S C P EIL G + H F+ G ++ YSC P Y L G A L C W
Sbjct: 142 SHTCGNPGEILKG---VLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFP 198
Query: 1703 APRC 1706
AP C
Sbjct: 199 APFC 202
Score = 35.8 bits (81), Expect = 0.44
Identities = 34/116 (29%), Positives = 45/116 (38%), Gaps = 22/116 (18%)
Query: 389 GFQLKGSSASYCVLAGMESLW-NSSVPVCEQIFCPSPPVIPNGRHT-GKPLEV------- 439
GFQL S S + +LW + V Q F V+P+ HT G P E+
Sbjct: 104 GFQLPSSIVS---TGSILTLWFTTDFAVSAQGFKALYEVLPS--HTCGNPGEILKGVLHG 158
Query: 440 --FPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHC 493
F G + Y+C P + L G + + C P W PAP C G C
Sbjct: 159 TRFNIGDKIRYSCLP------GYILEGHAILTCIVSPGNGASWDFPAPFCRAEGAC 208
Score = 35.8 bits (81), Expect = 0.44
Identities = 34/116 (29%), Positives = 45/116 (38%), Gaps = 22/116 (18%)
Query: 839 GFQLKGSSASYCVLAGMESLW-NSSVPVCEQIFCPSPPVIPNGRHT-GKPLEV------- 889
GFQL S S + +LW + V Q F V+P+ HT G P E+
Sbjct: 104 GFQLPSSIVS---TGSILTLWFTTDFAVSAQGFKALYEVLPS--HTCGNPGEILKGVLHG 158
Query: 890 --FPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHC 943
F G + Y+C P + L G + + C P W PAP C G C
Sbjct: 159 TRFNIGDKIRYSCLP------GYILEGHAILTCIVSPGNGASWDFPAPFCRAEGAC 208
Score = 33.5 bits (75), Expect = 2.2
Identities = 23/71 (32%), Positives = 29/71 (40%), Gaps = 15/71 (21%)
Query: 294 SRVCQPPPD----VLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQ----GD 345
S C P + VLH R F+ G ++ YSC PGY L G A + C
Sbjct: 142 SHTCGNPGEILKGVLHGTR-------FNIGDKIRYSCLPGYILEGHAILTCIVSPGNGAS 194
Query: 346 WSPAAPTCEVK 356
W AP C +
Sbjct: 195 WDFPAPFCRAE 205
>gi|62739186 complement factor H isoform a precursor [Homo sapiens]
Length = 1231
Score = 315 bits (806), Expect = 4e-85
Identities = 347/1325 (26%), Positives = 552/1325 (41%), Gaps = 167/1325 (12%)
Query: 27 LLAVVVLLALPVAWGQCNAPEW--LPFARPTNLT----DEFEFPIGTYLNYECRPGYSGR 80
LLA ++ L L W C A + LP R T + + +P GT Y+CRPGY
Sbjct: 3 LLAKIICLML---WAICVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRSL 59
Query: 81 PFSIICLKNSVWTGAKD--RCRRKSCRNPPDPVNGMVHVIKG--IQFGSQIKYSCTKGYR 136
I+ + W +C+++ C +P D G + G ++G + Y+C +GY+
Sbjct: 60 GNVIMVCRKGEWVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQ 119
Query: 137 LIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTI-TNGDFISTNRE---NFHYGSVVT 192
L+G + DT W N+ PIC+ + C LP T NG +S+ E +H+G V
Sbjct: 120 LLGEINYR---ECDTDGWTNDIPICEVVKC-LPVTAPENGKIVSSAMEPDREYHFGQAVR 175
Query: 193 YRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDN 252
+ CN G +++ G+ ++C+ + G WS P+C + C P+V NG +S
Sbjct: 176 FVCNSG------YKIEGDEEMHCSDD----GFWSKEKPKC-VEISCKSPDVINGSPIS-Q 223
Query: 253 RSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRD 312
+ ++ NE +++C G+ C + W P LPSC P + + + +
Sbjct: 224 KIIYKENERFQYKCNMGYEYSERGDAVCTE-SGWRP-LPSCEEKSCDNPYIPNGDYSPL- 280
Query: 313 KDNFSPGQEVFYSCEPG-YDLRGAASMRCTPQGDWSPAAPTCEVKSCD--DFM-GQLLN- 367
+ G E+ Y C G Y + +CT G W P AP C +K CD D G L +
Sbjct: 281 RIKHRTGDEITYQCRNGFYPATRGNTAKCTSTG-WIP-APRCTLKPCDYPDIKHGGLYHE 338
Query: 368 --GRVLFPVNLQLGAKVDFVCDEGFQLKGSS---ASYCVLAGMESLWNSSVPVCEQIFCP 422
R FPV +G + CDE F+ S +C G W+ +VP + + P
Sbjct: 339 NMRRPYFPV--AVGKYYSYYCDEHFETPSGSYWDHIHCTQDG----WSPAVPCLRKCYFP 392
Query: 423 SPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSS 482
N H K F GK+++ C P G + ++T+ C NG W S
Sbjct: 393 YLENGYNQNHGRK----FVQGKSIDVACHP----GYALPK-AQTTVTCME----NG-W-S 437
Query: 483 PAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY----GRPFSITCLD 538
P PRC + C + +++ + + + KY+C+ Y SITC
Sbjct: 438 PTPRCIRVKTCSKSSIDIENGFISESQYT-YALKEKAKYQCKLGYVTADGETSGSITCGK 496
Query: 539 NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILS 598
+ WS+ + C KSC P + T ++ ++Y C G+ S+ I+
Sbjct: 497 D-GWSA-QPTC-IKSCDIPVFMNARTKNDFTWFKLNDTLDYECHDGYESNTGSTTGSIVC 553
Query: 599 GNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELV 658
G WS PIC C L P I ++ + G V+ + C PG F +V
Sbjct: 554 GYNG-WSDL-PICYERECEL-PKIDVHLVPDRKKDQYKVGEVLKFSCKPG------FTIV 604
Query: 659 GEPSIYCTSNDDQVGIWSGPAPQC--IIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRC 716
G S+ C G+ S P C + + PP + NG + + + +EVVE+ C
Sbjct: 605 GPNSVQCY----HFGL-SPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEVVEYYC 659
Query: 717 QPGFVMKGPRRVKCQALNKWEPELPSC---SRVCQPPPDVLHAERTQRDKDNFSPGQEVF 773
P F+MKGP +++C +W LP C C P++ H Q + G V
Sbjct: 660 NPRFLMKGPNKIQC-VDGEW-TTLPVCIVEESTCGDIPELEHG-WAQLSSPPYYYGDSVE 716
Query: 774 YSCEPGYDLRGAASMRCTPQGDWSPAAPTC----EVKSCDDFMGQLLNGRVLFPVNLQLG 829
++C + + G S+ C G W+ P C ++K C + ++ +L+
Sbjct: 717 FNCSESFTMIGHRSITCI-HGVWT-QLPQCVAIDKLKKCKS------SNLIILEEHLKNK 768
Query: 830 AKVDFVCDEGFQLKGSSA---SYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKP 886
+ D + ++ +G + C+ + N S+ + CP PP IPN +
Sbjct: 769 KEFDHNSNIRYRCRGKEGWIHTVCINGRWDPEVNCSMAQIQ--LCPPPPQIPNSHNMTTT 826
Query: 887 LEVFPFGKAVNYTCDPHPDRGTSFDLIGE-STIRCTSDPQGNGVWSSPAPRCGILGHCQA 945
L + G+ V+ C + LI E I C +G W S P C C
Sbjct: 827 LN-YRDGEKVSVLCQEN-------YLIQEGEEITCK-----DGRWQS-IPLCVEKIPCSQ 872
Query: 946 PDHFLFAKLKTQTNASD-FPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSC 1004
P + + ++ + + GT L Y C + + T WSSP C+ C
Sbjct: 873 PPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMGKWSSPPQ-CEGLPC 931
Query: 1005 KTPPDPVNGMV-HVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQR 1063
K+PP+ +G+V H+ Q G + Y C G + G + A+C+ WS PP C +
Sbjct: 932 KSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCL----GEKWS-HPPSCIK 986
Query: 1064 IPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVG 1123
C P+ N + ++ + G VTY C +++ G ++ C ++
Sbjct: 987 TDCLSLPSFENAIPMGEKKDVYKAGEQVTYTC------ATYYKMDGASNVTCINSR---- 1036
Query: 1124 IWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 1183
W+G P C + PP V+N +VS S + E V ++C+ + M G V C
Sbjct: 1037 -WTG-RPTCRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMCLNG 1094
Query: 1184 NKWEPELPSC---SRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHC 1240
N EP P C + C PPP I +G+ T ++P V Y C+ Y L G + C
Sbjct: 1095 NWTEP--PQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLYQLEGNKRITC 1152
Query: 1241 TPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLF------PLNLQLGAKVSFVCDEGFRLKG 1294
G WS E P+C + C + + + L + G V FVC G+RL
Sbjct: 1153 R-NGQWS-EPPKC-LHPCVISREIMENYNIALRWTAKQKLYSRTGESVEFVCKRGYRL-- 1207
Query: 1295 SSVSH 1299
SS SH
Sbjct: 1208 SSRSH 1212
Score = 290 bits (743), Expect = 8e-78
Identities = 329/1273 (25%), Positives = 489/1273 (38%), Gaps = 203/1273 (15%)
Query: 574 GSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPI--CQRIPCGLPPTIANGDFISTN 631
G++ Y C G+R +G+ C W P+ CQ+ PCG P G F T
Sbjct: 45 GTQAIYKCRPGYRSLGNVIMVC----RKGEWVALNPLRKCQKRPCGHPGDTPFGTFTLTG 100
Query: 632 RENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP 691
F YG Y CN G ++L+GE + D W+ P C + KC P
Sbjct: 101 GNVFEYGVKAVYTCNEG------YQLLGEINYRECDTDG----WTNDIPICEVV-KCLPV 149
Query: 692 NV-ENGILVSDNRSL---FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC 747
ENG +VS + + V F C G+ ++G + C W E P C +
Sbjct: 150 TAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEIS 209
Query: 748 QPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKS 807
PDV++ + K + + Y C GY+ CT G W P P+CE KS
Sbjct: 210 CKSPDVINGSPISQ-KIIYKENERFQYKCNMGYEYSERGDAVCTESG-WRPL-PSCEEKS 266
Query: 808 CDDFMGQLLNGRVL-FPVNLQLGAKVDFVCDEGFQ--LKGSSASYCVLAGMESLWNSSVP 864
CD+ + NG + + G ++ + C GF +G++A C G W + P
Sbjct: 267 CDN--PYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAK-CTSTG----WIPA-P 318
Query: 865 VCEQIFCPSPPVIPNGR-HTGKPLEVFPF--GKAVNYTCDPHPDR--GTSFDLIGESTIR 919
C C P + G H FP GK +Y CD H + G+ +D I
Sbjct: 319 RCTLKPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWD-----HIH 373
Query: 920 CTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY- 978
CT D WS PA C L C P Q + F G S+ C P Y
Sbjct: 374 CTQDG-----WS-PAVPC--LRKCYFP---YLENGYNQNHGRKFVQGKSIDVACHPGYAL 422
Query: 979 -GRPFSITCLDNLVWSSPKDVCKRKSC-KTPPDPVNGMVHVIT-DIQVGSRINYSCTTGH 1035
++TC++N WS + K+C K+ D NG + + + Y C G+
Sbjct: 423 PKAQTTVTCMEN-GWSPTPRCIRVKTCSKSSIDIENGFISESQYTYALKEKAKYQCKLGY 481
Query: 1036 RLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNREN----FHYGSVV 1091
++ I G WS +P + C +P F++ +N F +
Sbjct: 482 VTADGETSGSITCGKDG-WSAQPTCIKS--CDIPV------FMNARTKNDFTWFKLNDTL 532
Query: 1092 TYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSD 1151
Y C+ G G SI C N WS P C +C P ++ ++
Sbjct: 533 DYECHDGYESN-TGSTTG--SIVCGYNG-----WSD-LPICY-ERECELPKIDVHLVPDR 582
Query: 1152 NRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCS---RVCQPPPEILHGEH 1208
+ + + EV++F C+PGF + GP V+C P+LP C + C PPPE+L+G
Sbjct: 583 KKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFGL-SPDLPICKEQVQSCGPPPELLNGNV 641
Query: 1209 TPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVK--SCDDFLGQLP 1266
++ + + V Y C P + ++G + C G+W+ P C V+ +C D + +L
Sbjct: 642 KEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCV-DGEWTT-LPVCIVEESTCGD-IPELE 698
Query: 1267 HGRV-LFPLNLQLGAKVSFVCDEGFRLKG-----------SSVSHCVLVGM--RSLWNNS 1312
HG L G V F C E F + G + + CV + + +N
Sbjct: 699 HGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCIHGVWTQLPQCVAIDKLKKCKSSNL 758
Query: 1313 VPVCEHI--------------------------------------------FCPNPPAIL 1328
+ + EH+ CP PP I
Sbjct: 759 IILEEHLKNKKEFDHNSNIRYRCRGKEGWIHTVCINGRWDPEVNCSMAQIQLCPPPPQIP 818
Query: 1329 NGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGEST-IRCTSDPHGNGVWSSPAPRC 1387
N H T + + G+++S C + LI E I C +G W S P C
Sbjct: 819 NS-HNMTTTLNYRDGEKVSVLCQEN-------YLIQEGEEITCK-----DGRWQS-IPLC 864
Query: 1388 ELSVRAGHCKTPEQFPFASPTIPINDFE-FPVGTSLNYECRPGY-FGKMFSISCLENLVW 1445
V C P Q + + E + GT L+Y C G+ + +C W
Sbjct: 865 ---VEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCYMGK-W 920
Query: 1446 SSVEDNCRRKSCGPPPEPFNGMV-HINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNN 1504
SS C C PPE +G+V H++ Q+G V Y C EGF + G CL
Sbjct: 921 SS-PPQCEGLPCKSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCL----G 975
Query: 1505 VTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGER 1564
W P C C P+ N + + G VTY C T +++ G
Sbjct: 976 EKWSHP-PSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCAT------YYKMDGAS 1028
Query: 1565 SIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFV 1624
++ C + W+ P C T+ P V+NA V S + E +R++C+ +
Sbjct: 1029 NVTCINSR-----WTGRPT-CRDTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSPYE 1082
Query: 1625 MVGSHTVQCQTNGRWG--PKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPS 1682
M G V C NG W P+ + C PPP I +G+ T ++P V Y C+
Sbjct: 1083 MFGDEEVMC-LNGNWTEPPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNL 1141
Query: 1683 YDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLL------PLNLQLGAKVS 1736
Y L G + C G WS E P+C + C + + + L L + G V
Sbjct: 1142 YQLEGNKRITCR-NGQWS-EPPKC-LHPCVISREIMENYNIALRWTAKQKLYSRTGESVE 1198
Query: 1737 FVCDEGFRLKGRS 1749
FVC G+RL RS
Sbjct: 1199 FVCKRGYRLSSRS 1211
Score = 242 bits (618), Expect = 2e-63
Identities = 319/1318 (24%), Positives = 512/1318 (38%), Gaps = 174/1318 (13%)
Query: 160 ICDRIPCGLPPTITNGDFI--STNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTS 217
IC C P N + + S + + + G+ Y+C PG + +G + C
Sbjct: 15 ICVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPG------YRSLGNVIMVCRK 68
Query: 218 NDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRR 277
+ + P +C P + G ++F + C G+ + G
Sbjct: 69 GE---WVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEIN 125
Query: 278 VKCQALNKWEPELPSCSRV-CQP---PPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLR 333
+ + W ++P C V C P P + + GQ V + C GY +
Sbjct: 126 YRECDTDGWTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIE 185
Query: 334 GAASMRCTPQGDWSPAAPTCEVKSC---DDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGF 390
G M C+ G WS P C SC D G ++ ++++ N + + C+ G+
Sbjct: 186 GDEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKEN----ERFQYKCNMGY 241
Query: 391 QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEV-FPFGKTVNYT 449
+ + C +G L P CE+ C + P IPNG ++ PL + G + Y
Sbjct: 242 EYSERGDAVCTESGWRPL-----PSCEEKSCDN-PYIPNGDYS--PLRIKHRTGDEITYQ 293
Query: 450 CDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTN 509
C R + +T +CTS W PAPRC L C PD
Sbjct: 294 C-----RNGFYPATRGNTAKCTSTG-----W-IPAPRC-TLKPCDYPDIKHGGLYHENMR 341
Query: 510 ASDFP--IGTSLKYECRPEYYGRPFS-----ITCLDNLVWSSPKDVCKRKSCKTPPDPVN 562
FP +G Y C E++ P I C + W SP C RK +
Sbjct: 342 RPYFPVAVGKYYSYYC-DEHFETPSGSYWDHIHCTQD-GW-SPAVPCLRKCYFPYLENGY 398
Query: 563 GMVHVITDIQVGSRINYSCTTGHRL-IGHSSAECILSGNAAHWSTKPPICQRIPCGLPPT 621
H +Q G I+ +C G+ L ++ C+ +G WS P + C
Sbjct: 399 NQNHGRKFVQ-GKSIDVACHPGYALPKAQTTVTCMENG----WSPTPRCIRVKTCSKSSI 453
Query: 622 IANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 681
FIS ++ + Y+C G GE S T D WS P
Sbjct: 454 DIENGFISESQYTYALKEKAKYQCKLG-----YVTADGETSGSITCGKDG---WSA-QPT 504
Query: 682 CIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGF---VMKGPRRVKCQALNKWEP 738
CI C P N +D + F LN+ +++ C G+ + C N W
Sbjct: 505 CI--KSCDIPVFMNARTKND-FTWFKLNDTLDYECHDGYESNTGSTTGSIVC-GYNGWS- 559
Query: 739 ELPSC-SRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWS 797
+LP C R C+ P +H R KD + G+ + +SC+PG+ + G S++C G S
Sbjct: 560 DLPICYERECELPKIDVHLV-PDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFG-LS 617
Query: 798 PAAPTC--EVKSCDDFMGQLLNGRVLFPVNLQLGAK--VDFVCDEGFQLKGSSASYCVLA 853
P P C +V+SC +LLNG V + G V++ C+ F +KG + CV
Sbjct: 618 PDLPICKEQVQSCGP-PPELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCV-- 674
Query: 854 GMESLWNSSVPVC--EQIFCPSPPVIPNG-RHTGKPLEVFPFGKAVNYTCDPHPDRGTSF 910
+ W +++PVC E+ C P + +G P + +G +V + C SF
Sbjct: 675 --DGEW-TTLPVCIVEESTCGDIPELEHGWAQLSSP--PYYYGDSVEFNC------SESF 723
Query: 911 DLIGESTIRCTSDPQGNGVWSSPAPRC---GILGHCQAPDHFLFAK-LKTQTNASDFPIG 966
+IG +I C +GVW+ P+C L C++ + + + LK N +F
Sbjct: 724 TMIGHRSITCI-----HGVWTQ-LPQCVAIDKLKKCKSSNLIILEEHLK---NKKEFDHN 774
Query: 967 TSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVIT---DIQV 1023
++++Y CR + + T N W + + PP P H +T + +
Sbjct: 775 SNIRYRCRGK---EGWIHTVCINGRWDPEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRD 831
Query: 1024 GSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFIS--TN 1081
G +++ C + + C W + P ++IPC PP I +G S ++
Sbjct: 832 GEKVSVLCQENYLIQEGEEITC----KDGRWQSIPLCVEKIPCSQPPQIEHGTINSSRSS 887
Query: 1082 RENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCI-IPNKCTP 1140
+E++ +G+ ++Y C G F + E C +G WS P PQC +P K +P
Sbjct: 888 QESYAHGTKLSYTCEGG------FRISEENETTC-----YMGKWSSP-PQCEGLPCK-SP 934
Query: 1141 PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQP 1199
P + +G++ + S + E V ++C GF + GP KC KW PSC + C
Sbjct: 935 PEISHGVVAHMSDS-YQYGEEVTYKCFEGFGIDGPAIAKCLG-EKWS-HPPSCIKTDCLS 991
Query: 1200 PPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCD 1259
P + +D + G++V Y+C Y + GA+++ C W+ P C SC
Sbjct: 992 LPSFENAIPMGEKKDVYKAGEQVTYTCATYYKMDGASNVTCI-NSRWTGR-PTCRDTSCV 1049
Query: 1260 DFLGQLPHGRVLFPLNLQL-----GAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVP 1314
+ P + + ++ Q+ G +V + C + + G C + W P
Sbjct: 1050 N----PPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDEEVMC----LNGNWTEP-P 1100
Query: 1315 VCEHIF--CPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTS 1372
C+ C PP I NG T P + Y C + L G I C
Sbjct: 1101 QCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQCQ------NLYQLEGNKRITCR- 1153
Query: 1373 DPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGY 1430
NG WS P P+C L + E + A G S+ + C+ GY
Sbjct: 1154 ----NGQWSEP-PKC-LHPCVISREIMENYNIALRWTAKQKLYSRTGESVEFVCKRGY 1205
Score = 221 bits (562), Expect = 7e-57
Identities = 301/1227 (24%), Positives = 479/1227 (39%), Gaps = 198/1227 (16%)
Query: 829 GAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPV--CEQIFCPSPPVIPNGRHTGKP 886
G + + C G++ G+ C + W + P+ C++ C P P G T
Sbjct: 45 GTQAIYKCRPGYRSLGNVIMVC----RKGEWVALNPLRKCQKRPCGHPGDTPFGTFTLTG 100
Query: 887 LEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIR-CTSDPQGNGVWSSPAPRCGILG--HC 943
VF +G YTC+ + L+GE R C +D W++ P C ++
Sbjct: 101 GNVFEYGVKAVYTCNE------GYQLLGEINYRECDTDG-----WTNDIPICEVVKCLPV 149
Query: 944 QAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY-YGRPFSITCLDNLVWSSPKDVCKRK 1002
AP++ + + ++ G ++++ C Y + C D+ WS K C
Sbjct: 150 TAPENGKIVSSAMEPDR-EYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPKCVEI 208
Query: 1003 SCKTPPDPVNGM-VHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPIC 1061
SCK+P D +NG + + R Y C G+ A C SG W P C
Sbjct: 209 SCKSP-DVINGSPISQKIIYKENERFQYKCNMGYEYSERGDAVCTESG----WRPLPS-C 262
Query: 1062 QRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQ 1121
+ C P I NGD+ S R G +TY+C G + + CTS
Sbjct: 263 EEKSCD-NPYIPNGDY-SPLRIKHRTGDEITYQCRNG-----FYPATRGNTAKCTSTG-- 313
Query: 1122 VGIWSGPAPQCIIPNKCTPPNVENGILVSDN--RSLF--SLNEVVEFRCQPGFVMKGPR- 1176
W PAP+C + C P++++G L +N R F ++ + + C F
Sbjct: 314 ---WI-PAPRCTL-KPCDYPDIKHGGLYHENMRRPYFPVAVGKYYSYYCDEHFETPSGSY 368
Query: 1177 --RVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRG 1234
+ C + W P +P C R C P L + +H F G+ + +C PGY L
Sbjct: 369 WDHIHCTQ-DGWSPAVP-CLRKCYFP--YLENGYNQNHGRKFVQGKSIDVACHPGYALPK 424
Query: 1235 AASLHCTPQGDWSPEAPRCA-VKSCDDFLGQLPHGRVL-FPLNLQLGAKVSFVCDEGFRL 1292
A + + WSP PRC VK+C + +G + L K + C G+
Sbjct: 425 AQTTVTCMENGWSP-TPRCIRVKTCSKSSIDIENGFISESQYTYALKEKAKYQCKLGYVT 483
Query: 1293 KGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDP 1352
S + G + W+ + P C I + P +N R D + K ++ T D
Sbjct: 484 ADGETSGSITCG-KDGWS-AQPTC--IKSCDIPVFMNAR----TKNDFTWFK-LNDTLDY 534
Query: 1353 HPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPIN 1412
G N G +T +G WS P C C+ P+ P +
Sbjct: 535 ECHDGYESNT-GSTTGSIVCGYNG---WSD-LPICY----ERECELPKIDVHLVPDRKKD 585
Query: 1413 DFEFPVGTSLNYECRPGY-FGKMFSISCLENLVWSSVEDNCRRK--SCGPPPEPFNGMVH 1469
++ VG L + C+PG+ S+ C + S C+ + SCGPPPE NG V
Sbjct: 586 QYK--VGEVLKFSCKPGFTIVGPNSVQCY-HFGLSPDLPICKEQVQSCGPPPELLNGNVK 642
Query: 1470 INTDTQFGST--VNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPIC--EIISCEPPPTI 1525
T ++G + V Y CN F + G C V G T P+C E +C P +
Sbjct: 643 EKTKEEYGHSEVVEYYCNPRFLMKGPNKIQC-VDGEWTT----LPVCIVEESTCGDIPEL 697
Query: 1526 SNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRC 1585
+G + + ++ G V + C + F ++G RSI C GVW+ P +C
Sbjct: 698 EHG-WAQLSSPPYYYGDSVEFNC------SESFTMIGHRSITCIH-----GVWTQLP-QC 744
Query: 1586 ISTNKCTAPEVENAIRVPG---NRSFFTLTEIIRFRCQ---------------------- 1620
++ +K + N I + N+ F IR+RC+
Sbjct: 745 VAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRYRCRGKEGWIHTVCINGRWDPEVNCS 804
Query: 1621 --------PGFVMVGSH--------------TVQCQTN-------------GRWGPKLPH 1645
P + SH +V CQ N GRW +P
Sbjct: 805 MAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSVLCQENYLIQEGEEITCKDGRW-QSIPL 863
Query: 1646 CSRV--CQPPPEILHG--EHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSP 1701
C C PP+I HG + S Q++++ G ++ Y+CE + + C G WS
Sbjct: 864 CVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRISEENETTCY-MGKWS- 921
Query: 1702 EAPRCTVKSCDDFLGQLPHGRVL-LPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKA 1760
P+C C ++ HG V + + Q G +V++ C EGF + G + + C+ G K
Sbjct: 922 SPPQCEGLPCKS-PPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCL--GEK- 977
Query: 1761 LWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESS 1820
W S P C + C + P+ N G G++++Y C T+ + + G S+
Sbjct: 978 -W-SHPPSCIKTDCLSLPSFENAIPMGEKKDVYKAGEQVTYTCATY------YKMDGASN 1029
Query: 1821 IRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPG 1880
+ C N W+ P C +C +PP +QN + + +S Y G + Y C
Sbjct: 1030 VTCI-----NSRWTG-RPTCR---DTSCVNPPTVQNAYIVSRQMSKYPSGERVRYQCRSP 1080
Query: 1881 YLLVGKGFIFCTDQGIWSQLDHYCKEV--NCSFPLFMNGISKELEMKKVYHYGDYVTLKC 1938
Y + G + C + G W++ CK+ C P ++ VY V +C
Sbjct: 1081 YEMFGDEEVMCLN-GNWTE-PPQCKDSTGKCGPPPPIDNGDITSFPLSVYAPASSVEYQC 1138
Query: 1939 EDGYTLEGSPWSQCQADDRWDPPLAKC 1965
++ Y LEG+ C+ +PP KC
Sbjct: 1139 QNLYQLEGNKRITCRNGQWSEPP--KC 1163
Score = 186 bits (472), Expect = 2e-46
Identities = 235/976 (24%), Positives = 374/976 (38%), Gaps = 141/976 (14%)
Query: 1060 ICQRIPCGLPPTIANGDFI--STNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTS 1117
IC C P N + + S + + + G+ Y+C G R +G + C
Sbjct: 15 ICVAEDCNELPPRRNTEILTGSWSDQTYPEGTQAIYKCRPGYRS------LGNVIMVCRK 68
Query: 1118 NDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRR 1177
+ + P +C P + G ++F + C G+ + G
Sbjct: 69 GE---WVALNPLRKCQKRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQLLGEIN 125
Query: 1178 VKCQALNKWEPELPSCSRV-CQP--PPE---ILHGEHTPSHQDNFSPGQEVFYSCEPGYD 1231
+ + W ++P C V C P PE I+ P + +F GQ V + C GY
Sbjct: 126 YRECDTDGWTNDIPICEVVKCLPVTAPENGKIVSSAMEPDREYHF--GQAVRFVCNSGYK 183
Query: 1232 LRGAASLHCTPQGDWSPEAPRCAVKSC---DDFLGQLPHGRVLFPLNLQLGAKVSFVCDE 1288
+ G +HC+ G WS E P+C SC D G ++++ N + + C+
Sbjct: 184 IEGDEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKEN----ERFQYKCNM 239
Query: 1289 GFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISY 1348
G+ + C G R L P CE C N P I NG ++ G EI+Y
Sbjct: 240 GYEYSERGDAVCTESGWRPL-----PSCEEKSCDN-PYIPNGDYSPLRIKH-RTGDEITY 292
Query: 1349 TCDP--HP-DRGMTFNLIGESTI---RCTSDP-------HGNGVWSSPAPRCELSVRAG- 1394
C +P RG T I RCT P HG G++ R V G
Sbjct: 293 QCRNGFYPATRGNTAKCTSTGWIPAPRCTLKPCDYPDIKHG-GLYHENMRRPYFPVAVGK 351
Query: 1395 --------HCKTPEQFPFA---------SPTIPI----------------NDFEFPVGTS 1421
H +TP + SP +P + +F G S
Sbjct: 352 YYSYYCDEHFETPSGSYWDHIHCTQDGWSPAVPCLRKCYFPYLENGYNQNHGRKFVQGKS 411
Query: 1422 LNYECRPGYF--GKMFSISCLENLVWSSVEDNCRRKSCGPPP-EPFNGMVHINTDT-QFG 1477
++ C PGY +++C+EN WS R K+C + NG + + T
Sbjct: 412 IDVACHPGYALPKAQTTVTCMEN-GWSPTPRCIRVKTCSKSSIDIENGFISESQYTYALK 470
Query: 1478 STVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTS 1537
Y C G+ ++ + G + W + P C I SC+ P ++ N+ T
Sbjct: 471 EKAKYQCKLGYVTADGETSGSITCGKD-GWSAQ-PTC-IKSCDIPVFMNART--KNDFTW 525
Query: 1538 FHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVE 1597
F + Y+CH DG + SI C WS P +C P+++
Sbjct: 526 FKLNDTLDYECH---DGYESNTGSTTGSIVCGYNG-----WSDLP--ICYERECELPKID 575
Query: 1598 NAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCS---RVCQPPP 1654
+ + + + E+++F C+PGF +VG ++VQC G P LP C + C PPP
Sbjct: 576 VHLVPDRKKDQYKVGEVLKFSCKPGFTIVGPNSVQCYHFG-LSPDLPICKEQVQSCGPPP 634
Query: 1655 EILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVK--SCD 1712
E+L+G ++ + + V Y C P + ++G + C G+W+ P C V+ +C
Sbjct: 635 ELLNGNVKEKTKEEYGHSEVVEYYCNPRFLMKGPNKIQCV-DGEWT-TLPVCIVEESTCG 692
Query: 1713 DFLGQLPHGRVLLPL-NLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQ 1771
D + +L HG L G V F C E F + G + C+ +W + +P C
Sbjct: 693 D-IPELEHGWAQLSSPPYYYGDSVEFNCSESFTMIGHRSITCI----HGVW-TQLPQCVA 746
Query: 1772 I----FCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDP 1827
I C + I+ H + + I Y C RG G C
Sbjct: 747 IDKLKKCKSSNLIILEEHLKNK-KEFDHNSNIRYRC-----RGKE----GWIHTVCI--- 793
Query: 1828 QGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKG 1887
NG W P C ++ CP PP+I N H + ++ Y G +S +C YL+
Sbjct: 794 --NGRW-DPEVNCSMAQIQLCPPPPQIPNSHNMTTTLN-YRDGEKVSVLCQENYLIQEGE 849
Query: 1888 FIFCTDQGIWSQLDHYCKEVNCSFP--LFMNGISKELEMKKVYHYGDYVTLKCEDGYTLE 1945
I C D G W + +++ CS P + I+ ++ Y +G ++ CE G+ +
Sbjct: 850 EITCKD-GRWQSIPLCVEKIPCSQPPQIEHGTINSSRSSQESYAHGTKLSYTCEGGFRIS 908
Query: 1946 GSPWSQCQADDRWDPP 1961
+ C +W P
Sbjct: 909 EENETTCYM-GKWSSP 923
Score = 73.2 bits (178), Expect = 2e-12
Identities = 61/248 (24%), Positives = 103/248 (41%), Gaps = 32/248 (12%)
Query: 1732 GAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPV--CEQIFCPNPPAILNGRHTGTP 1789
G + + C G+R S + ++ K W + P+ C++ C +P G T T
Sbjct: 45 GTQAIYKCRPGYR----SLGNVIMVCRKGEWVALNPLRKCQKRPCGHPGDTPFGTFTLTG 100
Query: 1790 FGDIPYGKEISYACDTHPDRGMTFNLIGESSIR-CTSDPQGNGVWSSPAPRCEL--SVPA 1846
YG + Y C+ + L+GE + R C +D W++ P CE+ +P
Sbjct: 101 GNVFEYGVKAVYTCNEG------YQLLGEINYRECDTDG-----WTNDIPICEVVKCLPV 149
Query: 1847 ACPHPPKIQNGHYIGGHVSL---YLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHY 1903
P +NG + + Y G + ++C+ GY + G + C+D G WS+
Sbjct: 150 TAP-----ENGKIVSSAMEPDREYHFGQAVRFVCNSGYKIEGDEEMHCSDDGFWSKEKPK 204
Query: 1904 CKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPLA 1963
C E++C P +NG + K +Y + KC GY + C + W PL
Sbjct: 205 CVEISCKSPDVING--SPISQKIIYKENERFQYKCNMGYEYSERGDAVC-TESGW-RPLP 260
Query: 1964 KCTSRTHD 1971
C ++ D
Sbjct: 261 SCEEKSCD 268
>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
Length = 3487
Score = 282 bits (721), Expect = 3e-75
Identities = 313/1226 (25%), Positives = 457/1226 (37%), Gaps = 226/1226 (18%)
Query: 552 KSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPIC 611
+ C P NG+V VG + + C G++L GH C G +W P C
Sbjct: 2121 QECPDPEPFANGIVRG-AGYNVGQSVTFECLPGYQLTGHPVLTC-QHGTNRNWDHPLPKC 2178
Query: 612 QRIPCGLPPTIANGDFISTNRENFHYGS---VVTYRCNPGSGGRKVFELVG-EPSIYCTS 667
+ +PCG T +NG S + + S V G G R L+ EPS
Sbjct: 2179 E-VPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPS----- 2232
Query: 668 NDDQVGIWSGP---APQCII---------------------------------------P 685
D + IW GP AP+ +
Sbjct: 2233 -GDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPL 2291
Query: 686 NKCTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ--ALNKWEPELPS 742
KC PP + N +V++N F++ ++V +RC PGF + G + C+ ++E P
Sbjct: 2292 TKCPPPTILPNAEVVTENEE-FNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPI 2350
Query: 743 CSRVCQPPPDVLHAERTQRDKDNFSPGQ-EVFYSC------EPGYDLR------------ 783
C C P + L + T PG F +C EP Y++
Sbjct: 2351 CEVHC--PTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQY 2408
Query: 784 ----------GAASMRCTPQGDWSP------------------------------AAPTC 803
G + + G++S +AP C
Sbjct: 2409 DEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYC 2468
Query: 804 EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGME-SLWNSS 862
+ L+G +L + Q G + F C+ G++L G S + C LW+ +
Sbjct: 2469 SLPRAP------LHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEA 2522
Query: 863 VPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTS 922
+P+C+ + C P NG GK V G Y+C G E+T C
Sbjct: 2523 IPLCQALSCGLPEAPKNGMVFGKEYTV---GTKAMYSCS----EGYHLQAGAEATAECLD 2575
Query: 923 DPQGNGVWSSP--APRCGILGHCQAPDHFLFAKLKTQTNA---SDFPIGTSLKYECRPEY 977
G+WS+ P+C + PD + + + + L C P Y
Sbjct: 2576 ----TGLWSNRNVPPQCVPV---TCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGY 2628
Query: 978 Y--GRPFSITCLDNLVWS--SPKDVCKRKSCKTPPDPVNGMVHVITDIQV-GSRINYSCT 1032
Y G+ I C N WS C+ SC P P NG H I + V G+ +SC
Sbjct: 2629 YYTGQRV-IRCQANGKWSLGDSTPTCRIISCGELPIPPNG--HRIGTLSVYGATAIFSCN 2685
Query: 1033 TGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVT 1092
+G+ L+G EC+ +G WS C CG P I NG N EN+ Y V
Sbjct: 2686 SGYTLVGSRVRECMANGL---WSGSEVRCLAGHCGTPEPIVNGHI---NGENYSYRGSVV 2739
Query: 1093 YRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDN 1152
Y+CN G F L+G C + WSG P C++ + P + + + D+
Sbjct: 2740 YQCNAG------FRLIGMSVRICQQDHH----WSGKTPFCVLVSCGHPGSPPHSQMSGDS 2789
Query: 1153 RSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSR----VCQPPPEILHGEH 1208
+++ VV + C + G C W LP CS VC P HG
Sbjct: 2790 ---YTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIR 2846
Query: 1209 TPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHG 1268
D+F PG + +SCE G+ LRG++ C G WS P C V SC + G +
Sbjct: 2847 LG---DSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGN-PGTPSNA 2902
Query: 1269 RVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAIL 1328
RV+F L + + + C EG+ G HC + G W S P C I C +P
Sbjct: 2903 RVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNG---TWTGSDPECLVINCGDPGIPA 2959
Query: 1329 NGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCE 1388
NG G D Y K ++Y C P G S + CT D W+ P C
Sbjct: 2960 NGLRLG---NDFRYNKTVTYQCVP----GYMMESHRVSVLSCTKD----RTWNGTKPVC- 3007
Query: 1389 LSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSI-SCLENLVWSS 1447
+A CK P P + +F G+S+ Y C GY + ++ +C N W+
Sbjct: 3008 ---KALMCKPPPLIPNGK----VVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTG 3060
Query: 1448 VEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTW 1507
C CG P P G + + S+V++SC+ L+GSP C G TW
Sbjct: 3061 ELPQCFPVFCGDPGVPSRGR-REDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDG---TW 3116
Query: 1508 DKKAPIC---EIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGER 1564
P C + +C P G NN + G+ V ++C G + L G
Sbjct: 3117 SGTQPSCIDPTLTTCADPGVPQFG--IQNNSQGYQVGSTVLFRCQKG------YLLQGST 3168
Query: 1565 SIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFV 1624
+ C WS PP C+ + C PE V G ++ + + CQ GF
Sbjct: 3169 TRTCLPN----LTWSGTPPDCV-PHHCRQPETPTHANV-GALDLPSMGYTLIYSCQEGFS 3222
Query: 1625 MV-GSHTVQCQTNGRWGPKLPHCSRV 1649
+ GS C+ +G W K P C V
Sbjct: 3223 LKGGSEHRTCKADGSWTGKPPICLEV 3248
Score = 281 bits (718), Expect = 6e-75
Identities = 475/2011 (23%), Positives = 723/2011 (35%), Gaps = 363/2011 (18%)
Query: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 162
SC +P P NG + G + C GY L GS+ +C+ + W P C
Sbjct: 1384 SCNDPGIPQNGS-RSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCI 1442
Query: 163 RIPCGLPPTITNGDFISTNR-ENFHYGSVVTYRC--NPGSGGRKVFELVG-EPS---IYC 215
PCG T +G +S N E + G ++ +P VF + EP ++
Sbjct: 1443 A-PCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHI 1501
Query: 216 TSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVM--- 272
D + G +P G + S + SLF GFV+
Sbjct: 1502 YDGRDSLSPLIGSFYGSQLP----------GRIESSSNSLFLAFRSDASVSNAGFVIDYT 1551
Query: 273 KGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDL 332
+ PR C P + + R D G V Y C GY++
Sbjct: 1552 ENPRES------------------CFDPGSIKNGTRVGSD---LKLGSSVTYYCHGGYEV 1590
Query: 333 RGAASMRCT--PQGD--WSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDE 388
G +++ C P G W+ P C ++G +G VL P N +C
Sbjct: 1591 EGTSTLSCILGPDGKPVWNNPRPVCTAPCGGQYVGS--DGVVLSP-NYPQNYTSGQICLY 1647
Query: 389 GFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIP-NGRHTGKPLEVFPFGKT-V 446
+ + A + N V V + S + +G HTG+ L + + +
Sbjct: 1648 FVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLI 1707
Query: 447 NYTCDP-HPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLK 505
++ P RG F + ++ R TS Q + V P PR G
Sbjct: 1708 KFSAKGLAPARG--FHFVYQAVPR-TSATQCSSV---PEPRYG----------------- 1744
Query: 506 TQTNASDFPIGTSLKYECRPEY--YGRPFSITCLDN----LVWSSPKDVC---------- 549
+ SDF +G +++EC Y G P I CL W+ C
Sbjct: 1745 -KRLGSDFSVGAIVRFECNSGYALQGSP-EIECLPVPGALAQWNVSAPTCVVPCGGNLTE 1802
Query: 550 KRKSCKTP--PDPVNGMVHVI----------TDIQVGSRI-------------------- 577
+R + +P P+P ++ + IQV S +
Sbjct: 1803 RRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTM 1862
Query: 578 --NYSCTTGHRLIGHSSAECIL------SGNAAHWSTKPPICQRIPCGLPPTIANGDFIS 629
++S TT L+ +S + L S +AA + + C P +NG +
Sbjct: 1863 LGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNG--VK 1920
Query: 630 TNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCT 689
T E + VV+++C PG + L G I C V W+ P P CI T
Sbjct: 1921 TG-ERYLVNDVVSFQCEPG------YALQGHAHISCMPGT--VRRWNYPPPLCIAQCGGT 1971
Query: 690 PPNVENGILVSDNRSLFSLN-----------------EVVEFRCQPGF----VMKGPRRV 728
+E IL + N + + F +P + GP
Sbjct: 1972 VEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEIRNGPYET 2031
Query: 729 KCQALNKWEPELPSCSRVCQPPPDV-LHAERTQRDKDNFSPGQEVFYSCE-----PGYDL 782
ELPS V H++ +Q Q++ YS + G+DL
Sbjct: 2032 SRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISSFLRGFDL 2091
Query: 783 RGAASMRCTPQ------GDWSPAAPTCEVKSCDD---FMGQLLNGRVLFPVNLQLGAKVD 833
TP D P E++ C D F ++ G +G V
Sbjct: 2092 SELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRG-----AGYNVGQSVT 2146
Query: 834 FVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFG 893
F C G+QL G C G W+ +P CE + C NG P P+
Sbjct: 2147 FECLPGYQLTGHPVLTCQ-HGTNRNWDHPLPKCE-VPCGGNITSSNGT-VYSPGFPSPYS 2203
Query: 894 KAVN--YTCDPHPDRGTSFDLIGESTIRCTSDPQGN--GVWSSP---APRCGILGHCQAP 946
+ + + G +L T +P G+ +W P APR G+ A
Sbjct: 2204 SSQDCVWLITVPIGHGVRLNLSLLQT-----EPSGDFITIWDGPQQTAPRLGVFTRSMAK 2258
Query: 947 DHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKT 1006
KT ++S+ + LK+ R G F+I + P C
Sbjct: 2259 --------KTVQSSSNQVL---LKFH-RDAATGGIFAIAFS-----AYPLTKC------- 2294
Query: 1007 PPDPVNGMVHVITD---IQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQ- 1062
PP + V+T+ +G + Y C G L+G+ C L G + PPIC+
Sbjct: 2295 PPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKL-GTYLQFEGPPPICEV 2353
Query: 1063 RIPCGLPPTIANGDFISTNRENFHYGSVVTYR-CNLGSRGRKVFELVGEPSIYCTSND-D 1120
P T + G +S + + GS ++ C+ R + + + + D
Sbjct: 2354 HCPTNELLTDSTGVILSQS----YPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYD 2409
Query: 1121 QVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKC 1180
+ I+ GP+ Q + + I+ S + S++ R
Sbjct: 2410 EFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYL------------------RWSSD 2451
Query: 1181 QALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHC 1240
A N+ ++ + C P LHG Q + PG + + C GY L G + C
Sbjct: 2452 HAYNRKGFKIRYSAPYCSLPRAPLHGFILG--QTSTQPGGSIHFGCNAGYRLVGHSMAIC 2509
Query: 1241 T--PQGD--WSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSS 1296
T PQG WS P C SC L + P ++F +G K + C EG+ L+ +
Sbjct: 2510 TRHPQGYHLWSEAIPLCQALSCG--LPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQAGA 2567
Query: 1297 --VSHCVLVGMRSLWNNS--VPVCEHIFCPNPPAIL--NGRHTGTPSGDIPYGKEISYTC 1350
+ C+ G LW+N P C + CP+ +I +GR + ++ C
Sbjct: 2568 EATAECLDTG---LWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLIC 2624
Query: 1351 DPHPDRGMTFNLIGESTIRCTSDPHGNGVWS--SPAPRCELSVRAGHCKTPEQFPFASPT 1408
DP + G+ IRC + NG WS P C + + G P T
Sbjct: 2625 DPG------YYYTGQRVIRCQA----NGKWSLGDSTPTCRI-ISCGELPIPPN-GHRIGT 2672
Query: 1409 IPINDFEFPVGTSLNYECRPGYFGKMFSI-SCLENLVWSSVEDNCRRKSCGPPPEPFNGM 1467
+ + G + + C GY + C+ N +WS E C CG P NG
Sbjct: 2673 LSV------YGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNG- 2725
Query: 1468 VHINTDT-QFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISC----EPP 1522
HIN + + +V Y CN GFRLIG C + W K P C ++SC PP
Sbjct: 2726 -HINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHH---WSGKTPFCVLVSCGHPGSPP 2781
Query: 1523 PTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPP 1582
+ +GD Y+ G VV Y C G++ LVG + C G W+
Sbjct: 2782 HSQMSGDSYTV-------GAVVRYSCI----GKRT--LVGNSTRMCGLD----GHWTGSL 2824
Query: 1583 PRCISTNK--CTAPEVE-NAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRW 1639
P C T+ C P + + IR+ + F ++RF C+ G V+ GS CQ NG W
Sbjct: 2825 PHCSGTSVGVCGDPGIPAHGIRLGDS---FDPGTVMRFSCEAGHVLRGSSERTCQANGSW 2881
Query: 1640 GPKLPHCSRV-CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGD 1698
P C + C P + S FS + Y C Y G S HC+ G
Sbjct: 2882 SGSQPECGVISCGNPGTPSNARVVFSDGLVFS--SSIVYECREGYYATGLLSRHCSVNGT 2939
Query: 1699 WSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGM 1758
W+ P C V +C D +P + L + + V++ C G+ ++ S VL+
Sbjct: 2940 WTGSDPECLVINCGD--PGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVS--VLSCT 2995
Query: 1759 K-ALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIG 1817
K WN + PVC+ + C PP I NG+ G+ D +G ++YAC L G
Sbjct: 2996 KDRTWNGTKPVCKALMCKPPPLIPNGKVVGS---DFMWGSSVTYAC-----------LEG 3041
Query: 1818 -ESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYI 1876
+ S+ +GNG W+ P+C P C P G S ++S+
Sbjct: 3042 YQLSLPAVFTCEGNGSWTGELPQC---FPVFCGDPGVPSRGRREDRGFSYR---SSVSFS 3095
Query: 1877 CDPGYLLVGKGFIFCTDQGIWSQLDHYCKE---VNCSFP-LFMNGISKELEMKKVYHYGD 1932
C P +LVG FC G WS C + C+ P + GI + Y G
Sbjct: 3096 CHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQNN---SQGYQVGS 3152
Query: 1933 YVTLKCEDGYTLEGSPWSQCQADDRWD--PP 1961
V +C+ GY L+GS C + W PP
Sbjct: 3153 TVLFRCQKGYLLQGSTTRTCLPNLTWSGTPP 3183
Score = 268 bits (685), Expect = 4e-71
Identities = 285/1097 (25%), Positives = 418/1097 (38%), Gaps = 219/1097 (19%)
Query: 1002 KSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPIC 1061
+ C P NG+V VG + + C G++L GH C G +W P C
Sbjct: 2121 QECPDPEPFANGIVRG-AGYNVGQSVTFECLPGYQLTGHPVLTC-QHGTNRNWDHPLPKC 2178
Query: 1062 QRIPCGLPPTIANGDFISTNRENFHYGS-----VVTYRCNLGSRGRKVFELVGEPSIYCT 1116
+ +PCG T +NG S + + S ++T G R + L EPS
Sbjct: 2179 E-VPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVR-LNLSLLQTEPS---- 2232
Query: 1117 SNDDQVGIWSGP---APQCII--------------------------------------- 1134
D + IW GP AP+ +
Sbjct: 2233 --GDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYP 2290
Query: 1135 PNKCTPPNV-ENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ--ALNKWEPELP 1191
KC PP + N +V++N F++ ++V +RC PGF + G + C+ ++E P
Sbjct: 2291 LTKCPPPTILPNAEVVTENEE-FNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPP 2349
Query: 1192 SCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSC------EPGYDLR------------ 1233
C C P E+L ++ F +C EP Y++
Sbjct: 2350 ICEVHC-PTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQY 2408
Query: 1234 ----------GAASLHCTPQGDWSPEAPRCAVKSCDDF---------------------- 1261
G + L G++S AP S +
Sbjct: 2409 DEFEIFDGPSGQSPLLKALSGNYS--APLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAP 2466
Query: 1262 ---LGQLP-HGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMR-SLWNNSVPVC 1316
L + P HG +L + Q G + F C+ G+RL G S++ C LW+ ++P+C
Sbjct: 2467 YCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLC 2526
Query: 1317 EHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHG 1376
+ + C P A NG G + G + Y+C G E+T C
Sbjct: 2527 QALSCGLPEAPKNGMVFGK---EYTVGTKAMYSCS----EGYHLQAGAEATAECLD---- 2575
Query: 1377 NGVWSSP--APRC---------ELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYE 1425
G+WS+ P+C +SV G + I + ++ L
Sbjct: 2576 TGLWSNRNVPPQCVPVTCPDVSSISVEHGRWRL------------IFETQYQFQAQLMLI 2623
Query: 1426 CRPGYF--GKMFSISCLENLVWSSVEDN--CRRKSCGPPPEPFNGMVHINTDTQFGSTVN 1481
C PGY+ G+ I C N WS + CR SCG P P NG I T + +G+T
Sbjct: 2624 CDPGYYYTGQRV-IRCQANGKWSLGDSTPTCRIISCGELPIPPNGH-RIGTLSVYGATAI 2681
Query: 1482 YSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNG 1541
+SCN G+ L+GS C+ +G W C C P I NG N + + G
Sbjct: 2682 FSCNSGYTLVGSRVRECMANG---LWSGSEVRCLAGHCGTPEPIVNGHINGENYS--YRG 2736
Query: 1542 TVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIR 1601
+VV YQC+ G F L+G C Q WS P C+ + C P +
Sbjct: 2737 SVV-YQCNAG------FRLIGMSVRIC----QQDHHWSGKTPFCVLVS-CGHPGSPPHSQ 2784
Query: 1602 VPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSR----VCQPPPEIL 1657
+ G+ +T+ ++R+ C +VG+ T C +G W LPHCS VC P
Sbjct: 2785 MSGDS--YTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPA 2842
Query: 1658 HGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQ 1717
HG + D+F PG + +SCE + LRG++ C G WS P C V SC + G
Sbjct: 2843 HG---IRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGN-PGT 2898
Query: 1718 LPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNP 1777
+ RV+ L + + + C EG+ G + HC + G W S P C I C +P
Sbjct: 2899 PSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGT---WTGSDPECLVINCGDP 2955
Query: 1778 PAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPA 1837
NG G D Y K ++Y C G S + CT D W+
Sbjct: 2956 GIPANGLRLGN---DFRYNKTVTYQCVP----GYMMESHRVSVLSCTKDR----TWNGTK 3004
Query: 1838 PRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIW 1897
P C+ + C PP I NG +G S ++ G +++Y C GY L C G W
Sbjct: 3005 PVCKALM---CKPPPLIPNGKVVG---SDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSW 3058
Query: 1898 SQLDHYCKEVNCSFPLFMNGI-SKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADD 1956
+ C V C P G+ S+ + + Y V+ C L GSP CQ+D
Sbjct: 3059 TGELPQCFPVFCGDP----GVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDG 3114
Query: 1957 RW--------DPPLAKC 1965
W DP L C
Sbjct: 3115 TWSGTQPSCIDPTLTTC 3131
Score = 260 bits (665), Expect = 8e-69
Identities = 309/1254 (24%), Positives = 447/1254 (35%), Gaps = 222/1254 (17%)
Query: 256 FSLNEVVEFRCQPGFVMKGPRRVKCQ--ALNKWEPELPSCSRVCQPPPDVLHAERTQRDK 313
+++ + V F C PG+ + G + CQ W+ LP C C
Sbjct: 2139 YNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCG--------------- 2183
Query: 314 DNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPT----------CEVKSCDDFMG 363
N + YS PG+ ++S C W P + + DF+
Sbjct: 2184 GNITSSNGTVYS--PGFPSPYSSSQDCV----WLITVPIGHGVRLNLSLLQTEPSGDFIT 2237
Query: 364 QLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVL--------AGMESLWNSSVPV 415
+ P +LG + + Q SS++ +L G+ ++ S+ P+
Sbjct: 2238 IWDGPQQTAP---RLGVFTRSMAKKTVQ---SSSNQVLLKFHRDAATGGIFAIAFSAYPL 2291
Query: 416 CEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQ 475
+ CP P ++PN + E F G V Y C P F L+G + C
Sbjct: 2292 TK---CPPPTILPNAEVVTEN-EEFNIGDIVRYRCLP------GFTLVGNEILTCKLGTY 2341
Query: 476 GNGVWSSPAPRCGILGHCQA---------------------------------PDH---- 498
+ P P C + HC PD+
Sbjct: 2342 LQ--FEGPPPICEV--HCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISL 2397
Query: 499 ----FLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLV---WSSPKDVCKR 551
FL K + D P G S + Y P +T N V WSS ++
Sbjct: 2398 TVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRK 2457
Query: 552 --------KSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAH 603
C P P++G + T Q G I++ C G+RL+GHS A C H
Sbjct: 2458 GFKIRYSAPYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYH 2517
Query: 604 -WSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPS 662
WS P+CQ + CGLP NG + + G+ Y C+ G + L +
Sbjct: 2518 LWSEAIPLCQALSCGLPEAPKNGMVFG---KEYTVGTKAMYSCSEG------YHL--QAG 2566
Query: 663 IYCTSNDDQVGIWS--GPAPQCIIPNKC---TPPNVENGILVSDNRSLFSLNEVVEFRCQ 717
T+ G+WS PQC +P C + +VE+G + + + C
Sbjct: 2567 AEATAECLDTGLWSNRNVPPQC-VPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICD 2625
Query: 718 PGFVMKGPRRVKCQALNKWE--PELPSCSRVC---QPPPDVLHAERTQRDKDNFSPGQEV 772
PG+ G R ++CQA KW P+C + P P H T G
Sbjct: 2626 PGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLS-----VYGATA 2680
Query: 773 FYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSC---DDFMGQLLNGRVLFPVNLQLG 829
+SC GY L G+ C G WS + C C + + +NG N
Sbjct: 2681 IFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHINGE-----NYSYR 2735
Query: 830 AKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEV 889
V + C+ GF+L G S C + W+ P C + C P P+ + +G +
Sbjct: 2736 GSVVYQCNAGFRLIGMSVRIC---QQDHHWSGKTPFCVLVSCGHPGSPPHSQMSG---DS 2789
Query: 890 FPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC-----GILGHCQ 944
+ G V Y+C L+G ST C D G W+ P C G+ G
Sbjct: 2790 YTVGAVVRYSCI------GKRTLVGNSTRMCGLD----GHWTGSLPHCSGTSVGVCGDPG 2839
Query: 945 APDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFS-ITCLDNLVWSSPKDVCKRKS 1003
P H + F GT +++ C + R S TC N WS + C S
Sbjct: 2840 IPAHGI-------RLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVIS 2892
Query: 1004 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQR 1063
C P P N V + S I Y C G+ G S C ++G W+ P C
Sbjct: 2893 CGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGT---WTGSDPECLV 2949
Query: 1064 IPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVG 1123
I CG P ANG + +F Y VTY+C G + E + CT +
Sbjct: 2950 INCGDPGIPANGLRLG---NDFRYNKTVTYQCVPG----YMMESHRVSVLSCTKD----R 2998
Query: 1124 IWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 1183
W+G P C PP + NG +V + F V + C G+ + P C+
Sbjct: 2999 TWNGTKPVCKALMCKPPPLIPNGKVVGSD---FMWGSSVTYACLEGYQLSLPAVFTCEGN 3055
Query: 1184 NKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTP 1242
W ELP C V C P G FS V +SC P L G+ C
Sbjct: 3056 GSWTGELPQCFPVFCGDPGVPSRGRR---EDRGFSYRSSVSFSCHPPLVLVGSPRRFCQS 3112
Query: 1243 QGDWSPEAPRC---AVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSH 1299
G WS P C + +C D G G Q+G+ V F C +G+ L+GS+
Sbjct: 3113 DGTWSGTQPSCIDPTLTTCAD-PGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRT 3171
Query: 1300 CVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIP-YGKEISYTCDPHPDRGM 1358
C+ W+ + P C C P H + D+P G + Y+C
Sbjct: 3172 CL---PNLTWSGTPPDCVPHHCRQPE---TPTHANVGALDLPSMGYTLIYSCQE------ 3219
Query: 1359 TFNLIGESTIR-CTSDPHGNGVWSSPAPRC-ELSVRAGHCKTPEQFPFASPTIP 1410
F+L G S R C +D G W+ P C E+ T + P IP
Sbjct: 3220 GFSLKGGSEHRTCKAD----GSWTGKPPICLEVRPSGRPINTAREPPLTQALIP 3269
Score = 251 bits (640), Expect = 7e-66
Identities = 288/1204 (23%), Positives = 435/1204 (36%), Gaps = 231/1204 (19%)
Query: 706 FSLNEVVEFRCQPGFVMKGPRRVKCQ--ALNKWEPELPSCSRVCQPPPDVLHAERTQRDK 763
+++ + V F C PG+ + G + CQ W+ LP C C
Sbjct: 2139 YNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCG--------------- 2183
Query: 764 DNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPT----------CEVKSCDDFMG 813
N + YS PG+ ++S C W P + + DF+
Sbjct: 2184 GNITSSNGTVYS--PGFPSPYSSSQDCV----WLITVPIGHGVRLNLSLLQTEPSGDFIT 2237
Query: 814 QLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVL--------AGMESLWNSSVPV 865
+ P +LG + + Q SS++ +L G+ ++ S+ P+
Sbjct: 2238 IWDGPQQTAP---RLGVFTRSMAKKTVQ---SSSNQVLLKFHRDAATGGIFAIAFSAYPL 2291
Query: 866 CEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQ 925
+ CP P ++PN + E F G V Y C P F L+G + C
Sbjct: 2292 TK---CPPPTILPNAEVVTEN-EEFNIGDIVRYRCLP------GFTLVGNEILTCKLGTY 2341
Query: 926 GNGVWSSPAPRCGILGHCQA---------------------------------PDH---- 948
+ P P C + HC PD+
Sbjct: 2342 LQ--FEGPPPICEV--HCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISL 2397
Query: 949 ----FLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLV---WSSPKDVCKR 1001
FL K + D P G S + Y P +T N V WSS ++
Sbjct: 2398 TVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRK 2457
Query: 1002 --------KSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAH 1053
C P P++G + T Q G I++ C G+RL+GHS A C H
Sbjct: 2458 GFKIRYSAPYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYH 2517
Query: 1054 -WSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPS 1112
WS P+CQ + CGLP NG + + G+ Y C+ G + E E
Sbjct: 2518 LWSEAIPLCQALSCGLPEAPKNGMVFG---KEYTVGTKAMYSCSEGYHLQAGAEATAE-- 2572
Query: 1113 IYCTSNDDQVGIWSGP--APQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFR----- 1165
C G+WS PQC+ P C P+V + I V R +F+
Sbjct: 2573 --CLDT----GLWSNRNVPPQCV-PVTC--PDVSS-ISVEHGRWRLIFETQYQFQAQLML 2622
Query: 1166 -CQPGFVMKGPRRVKCQALNKWE--PELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEV 1222
C PG+ G R ++CQA KW P+C + I H + G
Sbjct: 2623 ICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLSVY--GATA 2680
Query: 1223 FYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKV 1282
+SC GY L G+ C G WS RC C + +G + N V
Sbjct: 2681 IFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGT-PEPIVNGHINGE-NYSYRGSV 2738
Query: 1283 SFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTP------ 1336
+ C+ GFRL G SV C W+ P C + C +P + + + +G
Sbjct: 2739 VYQCNAGFRLIGMSVRICQ---QDHHWSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAV 2795
Query: 1337 -------------------------SGDIPY--GKEISYTCDP-------------HPDR 1356
+G +P+ G + DP P
Sbjct: 2796 VRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDPGT 2855
Query: 1357 GMTFNLIGESTIRCTSDP--HGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDF 1414
M F+ +R +S+ NG WS P C + + G+ TP ++ + +D
Sbjct: 2856 VMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGV-ISCGNPGTP-----SNARVVFSD- 2908
Query: 1415 EFPVGTSLNYECRPGYFGK-MFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTD 1473
+S+ YECR GY+ + S C N W+ + C +CG P P NG+ + D
Sbjct: 2909 GLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANGL-RLGND 2967
Query: 1474 TQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSN 1533
++ TV Y C G+ ++ S + L + TW+ P+C+ + C+PPP I NG +
Sbjct: 2968 FRYNKTVTYQCVPGY-MMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGS 3026
Query: 1534 NRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTA 1593
+ F G+ VTY C G ++L C G W+ P+C C
Sbjct: 3027 D---FMWGSSVTYACLEG------YQLSLPAVFTCEGN----GSWTGELPQCFPVF-CGD 3072
Query: 1594 PEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCS----RV 1649
P V + R F+ + F C P V+VGS CQ++G W P C
Sbjct: 3073 PGVPSRGRREDRG--FSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTT 3130
Query: 1650 CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVK 1709
C P G ++ + G V + C+ Y L+G+ + C P WS P C
Sbjct: 3131 CADPGVPQFGIQ--NNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPH 3188
Query: 1710 SCDDFLGQLPHGRVLLPLNL-QLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPV 1768
C + P + L+L +G + + C EGF LKG S A W P+
Sbjct: 3189 HCRQ--PETPTHANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKA--DGSWTGKPPI 3244
Query: 1769 CEQI 1772
C ++
Sbjct: 3245 CLEV 3248
Score = 248 bits (633), Expect = 4e-65
Identities = 257/980 (26%), Positives = 365/980 (37%), Gaps = 135/980 (13%)
Query: 13 GPPAPGLPFCCGGSLLA----VVVLLALPVAWGQCNAPEWLPFARPT---NLTDEFEFPI 65
GPP C LL V++ + P ++ Q WL P +LT E+
Sbjct: 2346 GPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSE 2405
Query: 66 GTYLNYECRPGYSGR-------------PFSIICLKNSVWT-----------GAKDRCRR 101
Y +E G SG+ P + NSV+ G K R
Sbjct: 2406 KQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA 2465
Query: 102 KSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTV-IWDNETPI 160
C P P++G + Q G I + C GYRL+G S A C +W P+
Sbjct: 2466 PYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPL 2525
Query: 161 CDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDD 220
C + CGLP NG + + G+ Y C+ G + L + T+
Sbjct: 2526 CQALSCGLPEAPKNGMVFG---KEYTVGTKAMYSCSEG------YHL--QAGAEATAECL 2574
Query: 221 QVGIWS--GPAPQCIIPNKC---TPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP 275
G+WS PQC +P C + +VE+G + + + C PG+ G
Sbjct: 2575 DTGLWSNRNVPPQC-VPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQ 2633
Query: 276 RRVKCQALNKWE--PELPSCSRVC---QPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY 330
R ++CQA KW P+C + P P H T G +SC GY
Sbjct: 2634 RVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLS-----VYGATAIFSCNSGY 2688
Query: 331 DLRGAASMRCTPQGDWSPAAPTCEVKSC---DDFMGQLLNGRVLFPVNLQLGAKVDFVCD 387
L G+ C G WS + C C + + +NG N V + C+
Sbjct: 2689 TLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHINGE-----NYSYRGSVVYQCN 2743
Query: 388 EGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVN 447
GF+L G S C + W+ P C + C P P+ + +G + + G V
Sbjct: 2744 AGFRLIGMSVRIC---QQDHHWSGKTPFCVLVSCGHPGSPPHSQMSG---DSYTVGAVVR 2797
Query: 448 YTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC-----GILGHCQAPDHFLFA 502
Y+C L+G ST C D G W+ P C G+ G P H +
Sbjct: 2798 YSCI------GKRTLVGNSTRMCGLD----GHWTGSLPHCSGTSVGVCGDPGIPAHGI-- 2845
Query: 503 KLKTQTNASDFPIGTSLKYECRPEYYGRPFS-ITCLDNLVWSSPKDVCKRKSCKTPPDPV 561
F GT +++ C + R S TC N WS + C SC P P
Sbjct: 2846 -----RLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPS 2900
Query: 562 NGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPT 621
N V + S I Y C G+ G S C ++G W+ P C I CG P
Sbjct: 2901 NARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGT---WTGSDPECLVINCGDPGI 2957
Query: 622 IANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 681
ANG + +F Y VTY+C PG + E + CT + W+G P
Sbjct: 2958 PANGLRLG---NDFRYNKTVTYQCVPG----YMMESHRVSVLSCTKD----RTWNGTKPV 3006
Query: 682 CIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELP 741
C PP + NG +V + F V + C G+ + P C+ W ELP
Sbjct: 3007 CKALMCKPPPLIPNGKVVGSD---FMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELP 3063
Query: 742 SCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAP 801
C V P V R +R+ FS V +SC P L G+ C G WS P
Sbjct: 3064 QCFPVFCGDPGV--PSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQP 3121
Query: 802 TC---EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESL 858
+C + +C D G G Q+G+ V F C +G+ L+GS+ C+
Sbjct: 3122 SCIDPTLTTCAD-PGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCL---PNLT 3177
Query: 859 WNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTI 918
W+ + P C C P P + G L++ G + Y+C F L G S
Sbjct: 3178 WSGTPPDCVPHHCRQPET-PTHANVG-ALDLPSMGYTLIYSCQ------EGFSLKGGSEH 3229
Query: 919 R-CTSDPQGNGVWSSPAPRC 937
R C +D G W+ P C
Sbjct: 3230 RTCKAD----GSWTGKPPIC 3245
Score = 145 bits (365), Expect = 5e-34
Identities = 440/2091 (21%), Positives = 704/2091 (33%), Gaps = 458/2091 (21%)
Query: 100 RRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYR-LIGSSSATCIISGDTVIWDNET 158
R C +P PVNG +Q GS I + C +G+ GS + TC++ +V+W++
Sbjct: 687 RHNECPDPGVPVNGK-RFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAV 745
Query: 159 PICDRIPCGLPPTITNGDFISTNRENFHYGSVV---TYRCNPGSGGRKVFELVGEPSIYC 215
C+ PCG T +G +S F+ ++ PG + F+ Y
Sbjct: 746 LRCE-APCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYD 804
Query: 216 TSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP 275
T +S AP + + P L+S + L+ L + GF ++
Sbjct: 805 TLEVRDGRTYS--APLIGVYHGTQVPQ----FLISTSNYLYLLFSTDKSHSDIGFQLR-Y 857
Query: 276 RRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGA 335
+ Q+ + +P +P ++ +R D F G V +SC+ GY L
Sbjct: 858 ETITLQSDHCLDPGIP------------VNGQRHGND---FYVGALVTFSCDSGYTLSDG 902
Query: 336 ASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLFP---------------------- 373
+ C P WS A P+CE C F+ Q +G +L P
Sbjct: 903 EPLECEPNFQWSRALPSCEA-LCGGFI-QGSSGTILSPGFPDFYPNNLNCTWIIETSHGK 960
Query: 374 --------VNLQLGAKVDFVCDEGF------QLKGSSASYCVLAGMESLWNSSVPVCEQI 419
+L+ G + + G QL GS + AG+ + + V
Sbjct: 961 GVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDF 1020
Query: 420 F-----------------CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDL 462
C P V G F G T+ ++C P + L
Sbjct: 1021 SMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQ---FGVGDTLTFSCFP------GYRL 1071
Query: 463 IGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNAS----DFPIGTS 518
G + I C + +WSSP PRC + C T T + +FP+ +
Sbjct: 1072 EGTARITCLGGRR--RLWSSPLPRC--VAEC--------GNSVTGTQGTLLSPNFPVNYN 1119
Query: 519 LKYECRPEYYGRPFSITCLDNLVWS-SPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRI 577
+EC +P L + S DV K + G+ +G +
Sbjct: 1120 NNHECIYSIQTQPGKGIQLKARAFELSEGDVLKVYDGNNNSARLLGVFS--HSEMMGVTL 1177
Query: 578 NYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHY 637
N S ++ L + AE G H+S+ + I C P T G + E
Sbjct: 1178 N-STSSSLWLDFITDAENTSKGFELHFSS----FELIKCEDPGTPKFG--YKVHDEGHFA 1230
Query: 638 GSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGI 697
GS V++ C+PG + L G + C S + + W P P C+ T +G
Sbjct: 1231 GSSVSFSCDPG------YSLRGSEELLCLSGERRT--WDRPLPTCVAECGGTVRGEVSGQ 1282
Query: 698 LVSDNRSL---FSLNEVVEFRCQPG------FVMKGPRRVKCQALNKWEPELPSCSRVCQ 748
++S +LN + + G F++ V L W+ + S + +
Sbjct: 1283 VLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVH-DVLRIWDGPVESGVLLKE 1341
Query: 749 PPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSC 808
L + F++ + G+ ++ + S T P P +S
Sbjct: 1342 LSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVS---TATSCNDPGIPQNGSRSG 1398
Query: 809 DDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQ 868
D + + G F CD G+ L+GS+ CV W S P C
Sbjct: 1399 DSW---------------EAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIA 1443
Query: 869 IFCPSPPVIPNGRHTGKPL-EVFPFGKAVNYTCDPHPD-----------RGTSFDLIGES 916
C P+G E +P GK ++ PD +D +
Sbjct: 1444 P-CGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIY 1502
Query: 917 TIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPE 976
R + P + S P G ++ + LF ++ + S+ G + Y P
Sbjct: 1503 DGRDSLSPLIGSFYGSQLP-----GRIESSSNSLFLAFRSDASVSN--AGFVIDYTENP- 1554
Query: 977 YYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHR 1036
R+SC P NG V +D+++GS + Y C G+
Sbjct: 1555 ------------------------RESCFDPGSIKNG-TRVGSDLKLGSSVTYYCHGGYE 1589
Query: 1037 LIGHSSAECILS-GNTAHWSTKPPICQRIPCGLPPTIANGDFISTN-RENFHYGSVVTYR 1094
+ G S+ CIL W+ P+C PCG ++G +S N +N+ G + Y
Sbjct: 1590 VEGTSTLSCILGPDGKPVWNNPRPVC-TAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYF 1648
Query: 1095 CNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRS 1154
+ K + + G+ + + T+ +D V + G + + + +G ++
Sbjct: 1649 VTV----PKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLSSL------SGSHTGESLP 1698
Query: 1155 LFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQD 1214
L + N+V+ G QA+ + + + C PE +G+ S
Sbjct: 1699 LATSNQVLIKFSAKGLAPARGFHFVYQAVPR------TSATQCSSVPEPRYGKRLGS--- 1749
Query: 1215 NFSPGQEVFYSCEPGYDLRGAASLHCTP----QGDWSPEAPRCAVKSCDDFLGQLPHGRV 1270
+FS G V + C GY L+G+ + C P W+ AP C V C L + G +
Sbjct: 1750 DFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVV-PCGGNLTE-RRGTI 1807
Query: 1271 LFP------LNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSL-----WNNSVPVCEHI 1319
L P LN L V EG ++ VS SL +N+V +
Sbjct: 1808 LSPGFPEPYLN-SLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTMLGSF 1866
Query: 1320 FCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGV 1379
PA+LN + + +IS + F+L ++ G+
Sbjct: 1867 SGTTVPALLNSTSNQL---YLHFYSDISVS-------AAGFHLEYKTV----------GL 1906
Query: 1380 WSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFS-IS 1438
S P P +V + KT E++ +ND ++++C PGY + + IS
Sbjct: 1907 SSCPEP----AVPSNGVKTGERY-------LVNDV-------VSFQCEPGYALQGHAHIS 1948
Query: 1439 CLENLV--WSSVEDNCRRKSCGPPPEPFNGMV-----------------HINTDTQFGST 1479
C+ V W+ C + CG E G++ I FG+
Sbjct: 1949 CMPGTVRRWNYPPPLCIAQ-CGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAH 2007
Query: 1480 V---NYSC---NEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSN 1533
+ N+S ++ + P T + G + ++S T+ +S
Sbjct: 2008 IQFLNFSTEPNHDYIEIRNGPYETSRMMGR---FSGSELPSSLLSTSHETTVYFHSDHSQ 2064
Query: 1534 NRTSF---HNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWS-SPPPRCISTN 1589
NR F + ++Q + G L EL S T VW P
Sbjct: 2065 NRPGFKLEYQDLTYSHQISSFLRGFDLSELERTNS---TPPVAASYVWDLDPGCEAYELQ 2121
Query: 1590 KCTAPE--VENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQ--TNGRWGPKLPH 1645
+C PE +R G + + + + F C PG+ + G + CQ TN W LP
Sbjct: 2122 ECPDPEPFANGIVRGAG----YNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPK 2177
Query: 1646 CSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEP----------SYDLR-GAASLHCT 1694
C C G T S+ +SPG YS + +R + L
Sbjct: 2178 CEVPC-------GGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTE 2230
Query: 1695 PQGDW-------SPEAPRCTV--KSCDDFLGQLPHGRVLL-------------------P 1726
P GD+ APR V +S Q +VLL P
Sbjct: 2231 PSGDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYP 2290
Query: 1727 L-------------------NLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVP 1767
L +G V + C GF L G C L G + P
Sbjct: 2291 LTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKL-GTYLQFEGPPP 2349
Query: 1768 VCEQIFCPNPPAILNGRHTGTPF-----GDIPYGKEISYACDTHPDRGMTFN-------- 1814
+CE + CP + + TG G P + S+ PD ++
Sbjct: 2350 ICE-VHCPTNELLTDS--TGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEK 2406
Query: 1815 --------------------LIGESSIRCTSDPQGNGV---WSS-------------PAP 1838
L G S N V WSS AP
Sbjct: 2407 QYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAP 2466
Query: 1839 RCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCT--DQG- 1895
C L P+ +I G S PG +I + C+ GY LVG CT QG
Sbjct: 2467 YCSL---------PRAPLHGFILGQTSTQ-PGGSIHFGCNAGYRLVGHSMAICTRHPQGY 2516
Query: 1896 -IWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLE 1945
+WS+ C+ ++C P + K Y G C +GY L+
Sbjct: 2517 HLWSEAIPLCQALSCGLP---EAPKNGMVFGKEYTVGTKAMYSCSEGYHLQ 2564
Score = 95.1 bits (235), Expect = 6e-19
Identities = 225/1017 (22%), Positives = 342/1017 (33%), Gaps = 243/1017 (23%)
Query: 88 KNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCI- 146
K SV T C +P P G + + GS ++++C +GY L GS TC+
Sbjct: 327 KTSVLTQVGVSQGHNMCPDPGIPERGK-RLGSDFRLGSSVQFTCNEGYDLQGSKRITCMK 385
Query: 147 ISGDTVIWDNETPICDRIPC-----GLPPTITNGDFISTNRENFHYGSVVTYRCNP---- 197
+S W + P+C C G IT+ +F N H ++T NP
Sbjct: 386 VSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIIT-ALNPSKVI 444
Query: 198 ------------------GSGGRK------VFELVGE--PSIYCTSNDDQVGIWSGPAPQ 231
G GG+ ++ L G P + ++N ++
Sbjct: 445 KLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSG 504
Query: 232 CIIPNKCTPPNVEN------GILVSDNR--SLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 283
+ K + +E GI R S F + ++F CQP F + G + + CQ
Sbjct: 505 SSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKN 564
Query: 284 NKWEPELPSCSRVC----QPPPDVLHAERTQRDKDNF---------SPGQEVFYS----- 325
N+W + P C C P V+ + D N P + +
Sbjct: 565 NQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDID 624
Query: 326 CEPGYDL-------RGAASMRCTPQGDWSPAA---------------------------P 351
EP +D A + T G+ P++
Sbjct: 625 VEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFT 684
Query: 352 TCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGF-QLKGSSASYCVLAGMESLWN 410
T C D G +NG+ F +LQLG+ + F+CDEGF +GS CVL +WN
Sbjct: 685 TFRHNECPD-PGVPVNGK-RFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWN 742
Query: 411 SSVPVCE-----QIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGE 465
S+V CE + PS ++ G G + + P +FD
Sbjct: 743 SAVLRCEAPCGGHLTSPSGTILSPG-WPGFYKDALSCAWVIE--AQPGYPIKITFDRFKT 799
Query: 466 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFL----FAKLKTQTNASDFPIGTSLKY 521
T + + +S AP G+ Q P + + L T+ S IG L+Y
Sbjct: 800 EVNYDTLEVRDGRTYS--APLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRY 857
Query: 522 ECRPEYYGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSC 581
E +IT + C P PVNG H D VG+ + +SC
Sbjct: 858 E----------TIT-------------LQSDHCLDPGIPVNGQRHG-NDFYVGALVTFSC 893
Query: 582 TTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVV 641
+G+ L EC + WS P C+ + CG ++G +S +F+ ++
Sbjct: 894 DSGYTLSDGEPLECEPN---FQWSRALPSCEAL-CGGFIQGSSGTILSPGFPDFYPNNLN 949
Query: 642 TYRCNPGSGGRKVFELV-------GEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVE 694
S G+ VF G + T N G ++ P Q + P +
Sbjct: 950 CTWIIETSHGKGVFFTFHTFHLESGHDYLLITEN----GSFTQPLRQ--LTGSRLPAPIS 1003
Query: 695 NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVL 754
G+ + F Q F+ + + E +L C P +
Sbjct: 1004 AGLYGN-------------FTAQVRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSI- 1049
Query: 755 HAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCT--PQGDWSPAAPTCEVK---SCD 809
R F G + +SC PGY L G A + C + WS P C + S
Sbjct: 1050 ------RKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECGNSVT 1103
Query: 810 DFMGQLLNGRVLFPVN------------------LQLGAKVDFVCDEGFQLK-----GSS 846
G LL+ FPVN +QL A+ F EG LK +S
Sbjct: 1104 GTQGTLLSPN--FPVNYNNNHECIYSIQTQPGKGIQLKARA-FELSEGDVLKVYDGNNNS 1160
Query: 847 A------SYCVLAGM------ESLWNSSVPVCEQ--------------IFCPSPPVIPNG 880
A S+ + G+ SLW + E I C P G
Sbjct: 1161 ARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCEDPGTPKFG 1220
Query: 881 RHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRC 937
E G +V+++CDP + L G + C S + W P P C
Sbjct: 1221 YKVHD--EGHFAGSSVSFSCDP------GYSLRGSEELLCLSGER--RTWDRPLPTC 1267
Score = 80.1 bits (196), Expect = 2e-14
Identities = 237/1065 (22%), Positives = 366/1065 (34%), Gaps = 214/1065 (20%)
Query: 301 PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGD----WSPAAPTCEVK 356
PD ER +R +F G V ++C GYDL+G+ + C D WS P C +
Sbjct: 344 PDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRAR 403
Query: 357 SCD-------------DFMGQLLNG-------RVLFPVNLQLGAKVDFVCDEGFQ----- 391
CD +F Q N L P + A +F + G+
Sbjct: 404 MCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVG 463
Query: 392 --------------LKGSSASYCVLAGMESLW--------------NSSVPVCEQIFCPS 423
L G+S +++ +W +S EQ C
Sbjct: 464 DGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGD 523
Query: 424 PPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSP 483
P + GR G F G T+ + C P +F+L+G+ I C Q N WS+
Sbjct: 524 PGIPAYGRREGSR---FHHGDTLKFECQP------AFELVGQKAITC----QKNNQWSAK 570
Query: 484 APRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFS-ITCLDNLVW 542
P C + C F F + ++P C RP S I N +
Sbjct: 571 KPGC--VFSC----FFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDID 624
Query: 543 SSPK-DVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNA 601
P+ D K T PV G + Q+ S I ++GH + + S
Sbjct: 625 VEPQFDFLVIKDGATAEAPVLG---TFSGNQLPSSIT---SSGH--VARLEFQTDHSTGK 676
Query: 602 AHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEP 661
++ + C P NG ++ GS +++ C+ G G + G
Sbjct: 677 RGFNITFTTFRHNECPDPGVPVNGKRFG---DSLQLGSSISFLCDEGFLGTQ-----GSE 728
Query: 662 SIYCTSNDDQVGIWSGPAPQCIIP--NKCTPPNVENGILVSDN-----RSLFSLNEVVEF 714
+I C + V +W+ +C P T P +G ++S + S V+E
Sbjct: 729 TITCVLKEGSV-VWNSAVLRCEAPCGGHLTSP---SGTILSPGWPGFYKDALSCAWVIE- 783
Query: 715 RCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFY 774
QPG+ +K +N E+ P V H + + + S + +
Sbjct: 784 -AQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLF 842
Query: 775 SCEP-----GYDLRGAASMRCTPQGD--WSPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQ 827
S + G+ LR T Q D P P + +DF
Sbjct: 843 STDKSHSDIGFQLRYET---ITLQSDHCLDPGIPVNGQRHGNDF---------------Y 884
Query: 828 LGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCE------------QIFCPS-P 874
+GA V F CD G+ L C W+ ++P CE I P P
Sbjct: 885 VGALVTFSCDSGYTLSDGEPLEC---EPNFQWSRALPSCEALCGGFIQGSSGTILSPGFP 941
Query: 875 PVIPNGRHTGKPLEVFPFGKAVNYTCDP-HPDRGTSFDLIGESTIRCTSDPQGNGVWSSP 933
PN + +E GK V +T H + G + LI E+ Q G P
Sbjct: 942 DFYPNNLNCTWIIET-SHGKGVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGS-RLP 999
Query: 934 AP-RCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVW 992
AP G+ G+ A F+ SDF S+ YE F+IT
Sbjct: 1000 APISAGLYGNFTAQVRFI----------SDF----SMSYE--------GFNIT------- 1030
Query: 993 SSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTA 1052
S D+ + C+ P P + VG + +SC G+RL G + C L G
Sbjct: 1031 FSEYDL---EPCEEPEVPAYS-IRKGLQFGVGDTLTFSCFPGYRLEGTARITC-LGGRRR 1085
Query: 1053 HWSTKPPICQRIPCGLPPTIANGDFISTN-RENFHYGSVVTYRCNLGSRGRKVFELVGEP 1111
WS+ P C CG T G +S N N++ Y ++ ++ K +L +
Sbjct: 1086 LWSSPLPRCV-AECGNSVTGTQGTLLSPNFPVNYNNNHECIY--SIQTQPGKGIQL--KA 1140
Query: 1112 SIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFV 1171
+ S D + ++ G + + + L S + SL+ ++F
Sbjct: 1141 RAFELSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLW-----LDFITDAENT 1195
Query: 1172 MKGPRRVKCQALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGY 1230
KG +E S + C+ P G H + G V +SC+PGY
Sbjct: 1196 SKG-----------FELHFSSFELIKCEDPGTPKFGYKV--HDEGHFAGSSVSFSCDPGY 1242
Query: 1231 DLRGAASLHCT--PQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFP 1273
LRG+ L C + W P C + G++ G+VL P
Sbjct: 1243 SLRGSEELLCLSGERRTWDRPLPTCVAECGGTVRGEV-SGQVLSP 1286
Score = 73.2 bits (178), Expect = 2e-12
Identities = 111/451 (24%), Positives = 161/451 (35%), Gaps = 110/451 (24%)
Query: 1457 CGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCL-VSGNNVTWDKKAPICE 1515
C P P G + +D + GS+V ++CNEG+ L GS TC+ VS W P+C
Sbjct: 343 CPDPGIPERGK-RLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCR 401
Query: 1516 IISCE-----PPPTISNGDF---YSNNR------TSFHNGTVVT-----------YQCHT 1550
C+ P I++ +F Y NN T+ + V+ Y T
Sbjct: 402 ARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLT 461
Query: 1551 ----GPDGEQ---LFELVG----------ERSIYCTSKDDQVG--VWSSPPPRCISTNKC 1591
G DG+Q L+ L G ++ + D G + I C
Sbjct: 462 VGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSC 521
Query: 1592 TAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQ 1651
P + R G+R F + ++F CQP F +VG + CQ N +W K P C C
Sbjct: 522 GDPGIPAYGRREGSR--FHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSC- 578
Query: 1652 PPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCT------PQGDWSPEAPR 1705
NF+ V S P+Y LHC P+
Sbjct: 579 --------------FFNFTSPSGVVLS--PNYPEDYGNHLHCVWLILARPESRIHLAFND 622
Query: 1706 CTVKSCDDFL----GQLPHGRVL-------LPLNLQLG---AKVSFVCDEGFRLKGRSAS 1751
V+ DFL G VL LP ++ A++ F D +G
Sbjct: 623 IDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRG---- 678
Query: 1752 HCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGD-IPYGKEISYACDTHPDRG 1810
+N + CP+P +NG+ FGD + G IS+ CD
Sbjct: 679 ----------FNITFTTFRHNECPDPGVPVNGKR----FGDSLQLGSSISFLCDEG---- 720
Query: 1811 MTFNLIGESSIRCTSDPQGNGVWSSPAPRCE 1841
G +I C +G+ VW+S RCE
Sbjct: 721 -FLGTQGSETITCVL-KEGSVVWNSAVLRCE 749
Score = 71.2 bits (173), Expect = 9e-12
Identities = 171/801 (21%), Positives = 261/801 (32%), Gaps = 199/801 (24%)
Query: 1004 CKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECI-LSGNTAHWSTKPPICQ 1062
C P P G + +D ++GS + ++C G+ L G C+ +S A WS P+C+
Sbjct: 343 CPDPGIPERGK-RLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCR 401
Query: 1063 RIPC-----GLPPTIANGDFISTNRENFHYGSVVTY---------------------RCN 1096
C G I + +F N H ++T
Sbjct: 402 ARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLT 461
Query: 1097 LGSRGRK------VFELVGE--PSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENG-- 1146
+G G+ ++ L G P + ++N ++ + K + +E G
Sbjct: 462 VGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSC 521
Query: 1147 ----ILVSDNR--SLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC--- 1197
I R S F + ++F CQP F + G + + CQ N+W + P C C
Sbjct: 522 GDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFN 581
Query: 1198 --QPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDW-------SP 1248
P +L + + ++ + E L + PQ D+ +
Sbjct: 582 FTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHL-AFNDIDVEPQFDFLVIKDGATA 640
Query: 1249 EAPRCAVKSCDDFLGQLPH-GRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRS 1307
EAP S + + G V A++ F D +G +++
Sbjct: 641 EAPVLGTFSGNQLPSSITSSGHV---------ARLEFQTDHSTGKRGFNITFTTF----- 686
Query: 1308 LWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGEST 1367
H CP+P +NG+ G + G IS+ CD G T
Sbjct: 687 ---------RHNECPDPGVPVNGKRFG---DSLQLGSSISFLCDEG-----FLGTQGSET 729
Query: 1368 IRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPF-------------------ASPT 1408
I C G+ VW+S RCE GH +P A P
Sbjct: 730 ITCVL-KEGSVVWNSAVLRCEAPC-GGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPG 787
Query: 1409 IPINDFEFPVGTSLNY---ECRPG----------YFGK-----MFSISCLENLVWSSVED 1450
PI T +NY E R G Y G + S S L++S+ +
Sbjct: 788 YPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKS 847
Query: 1451 N-------------CRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTT 1497
+ + C P P NG H N D G+ V +SC+ G+ L
Sbjct: 848 HSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGN-DFYVGALVTFSCDSGYTLSDGEPLE 906
Query: 1498 CLVSGNNVTWDKKAPICE-----IISCEPPPTISNG--DFYSNN-------RTSFHNG-- 1541
C N W + P CE I +S G DFY NN TS G
Sbjct: 907 C---EPNFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVF 963
Query: 1542 -TVVTYQCHTGPD----------GEQLFELVGERSIYCTSKDDQVGVWS--SPPPRCIS- 1587
T T+ +G D + L +L G R G++ + R IS
Sbjct: 964 FTFHTFHLESGHDYLLITENGSFTQPLRQLTGSR----LPAPISAGLYGNFTAQVRFISD 1019
Query: 1588 ----------------TNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTV 1631
C PEV G + F + + + F C PG+ + G+ +
Sbjct: 1020 FSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQ--FGVGDTLTFSCFPGYRLEGTARI 1077
Query: 1632 QCQTNGR--WGPKLPHCSRVC 1650
C R W LP C C
Sbjct: 1078 TCLGGRRRLWSSPLPRCVAEC 1098
Score = 60.5 bits (145), Expect = 2e-08
Identities = 132/654 (20%), Positives = 209/654 (31%), Gaps = 181/654 (27%)
Query: 1453 RRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFR-LIGSPSTTCLVSGNNVTWDKKA 1511
R C P P NG Q GS++++ C+EGF GS + TC++ +V W+
Sbjct: 687 RHNECPDPGVPVNGK-RFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAV 745
Query: 1512 PICEIISCEPPPTISNGDFYSNNRTSFHNG------------------------TVVTYQ 1547
CE C T +G S F+ T V Y
Sbjct: 746 LRCEA-PCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYD 804
Query: 1548 CHTGPDGEQL---------------FELVGERSIYCTSKDDQ----VGVWSSPPPRCIST 1588
DG F + +Y D+ +G + +
Sbjct: 805 TLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQS 864
Query: 1589 NKCTAPEVENAIRVPGNR--SFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHC 1646
+ C P I V G R + F + ++ F C G+ + ++C+ N +W LP C
Sbjct: 865 DHCLDP----GIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSC 920
Query: 1647 SR------------VCQPP-PEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHC 1693
+ P P+ + S G+ VF++ + G L
Sbjct: 921 EALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLI 980
Query: 1694 TPQGDWSPEAPRCT-------------------VKSCDDFL------------------- 1715
T G ++ + T V+ DF
Sbjct: 981 TENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLEPCE 1040
Query: 1716 -GQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQ--- 1771
++P + L +G ++F C G+RL+G + C L G + LW+S +P C
Sbjct: 1041 EPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITC-LGGRRRLWSSPLPRCVAECG 1099
Query: 1772 ---------IFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNL----IGE 1818
+ PN P N H E Y+ T P +G+ + E
Sbjct: 1100 NSVTGTQGTLLSPNFPVNYNNNH------------ECIYSIQTQPGKGIQLKARAFELSE 1147
Query: 1819 SSIRCTSDPQGN-----GVWS-SPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMT 1872
+ D N GV+S S L+ ++ SL+L +T
Sbjct: 1148 GDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSS-----------------SLWLDFIT 1190
Query: 1873 ISYICDPGYLLVGKGF--IFCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHY 1930
+ G+ L F I C D G P F + E +
Sbjct: 1191 DAENTSKGFELHFSSFELIKCEDPGT---------------PKFGYKVHDE-----GHFA 1230
Query: 1931 GDYVTLKCEDGYTLEGSPWSQCQADDR--WDPPLAKCTSRTHDALIVGTLSGTI 1982
G V+ C+ GY+L GS C + +R WD PL C + + G +SG +
Sbjct: 1231 GSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAEC-GGTVRGEVSGQV 1283
Score = 48.9 bits (115), Expect = 5e-05
Identities = 104/483 (21%), Positives = 171/483 (35%), Gaps = 85/483 (17%)
Query: 1140 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK----WEPELPS--- 1192
P + NGI S F+L + V + C GF ++G + C A ++ W+ LPS
Sbjct: 142 PGRLPNGI---QQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRA 198
Query: 1193 ---CSRVCQPPPEILHGEHTPSHQDNFSP---------GQEVF-----YSCEPGYDLRGA 1235
C + I+ H PS N + G + + E GYD
Sbjct: 199 DDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEV 258
Query: 1236 ASLHCTPQGDWSPEAPRCAVKSCD----DFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFR 1291
+ P + S + F H + F Q+ ++ + G +
Sbjct: 259 TGTEGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIE-LKSRGVK 317
Query: 1292 L---KGSSVSHCVLVGMRSLWNNSVPVCE-HIFCPNPPAILNGRHTGTPSGDIPYGKEIS 1347
L K +S VL V V + H CP+P G+ G+ D G +
Sbjct: 318 LMPSKDNSQKTSVL--------TQVGVSQGHNMCPDPGIPERGKRLGS---DFRLGSSVQ 366
Query: 1348 YTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASP 1407
+TC+ ++L G I C WS P C + H + P SP
Sbjct: 367 FTCNE------GYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGI-ITSP 419
Query: 1408 TIPI----NDFEFPVGTSLNYECRPGYFGKMFSISCLENLVWSSVEDNCRRKSCGPPPEP 1463
PI N + T+LN P K+ E D G +
Sbjct: 420 NFPIQYDNNAHCVWIITALN----PSKVIKL----AFEEFDLERGYDTLTVGDGGQDGDQ 471
Query: 1464 FNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPP 1523
+++I T T + + ++ + L + SG+++ + E SC P
Sbjct: 472 -KTVLYILTGTSVPDLIVSTNHQMWLLFQTDG-----SGSSLGFKASYEEIEQGSCGDPG 525
Query: 1524 TISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPP 1583
+ G + FH+G + ++C + FELVG+++I C K++Q WS+ P
Sbjct: 526 IPAYG---RREGSRFHHGDTLKFEC------QPAFELVGQKAITC-QKNNQ---WSAKKP 572
Query: 1584 RCI 1586
C+
Sbjct: 573 GCV 575
Score = 47.0 bits (110), Expect = 2e-04
Identities = 111/530 (20%), Positives = 180/530 (33%), Gaps = 107/530 (20%)
Query: 1460 PPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISC 1519
PP+P N + + V+ + RLI + + G + T++ + +C
Sbjct: 86 PPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSA--QGFHATYE----VLPSHTC 139
Query: 1520 EPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWS 1579
P + NG ++F+ G V Y C+ G F L G + C + + W
Sbjct: 140 GNPGRLPNG---IQQGSTFNLGDKVRYSCNLG------FFLEGHAVLTCHAGSENSATWD 190
Query: 1580 SPPPRCISTNKC-----------TAPEVENAIRVPGNRSFFTLTEI--------IRFRCQ 1620
P P C + + C ++P + + ++ L E+ I F+ +
Sbjct: 191 FPLPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLE 250
Query: 1621 PGFVMVGSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGE----HTLSHQDNFSPGQEVF 1676
G+ + + G G L + P P I H S ++ G
Sbjct: 251 DGYDFL-------EVTGTEGSSL-WFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQ 302
Query: 1677 YSCEPSYDLRGAASLHCTPQGDWSPEAPRCTV-------KSCDDFLGQLPHGRVLLPLNL 1729
Y + +L+ + + P D S + T C D +P L +
Sbjct: 303 YQVKKQIELK-SRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPD--PGIPERGKRLGSDF 359
Query: 1730 QLGAKVSFVCDEGFRLKGRSASHCV-LAGMKALWNSSVPVCEQIFC-------------P 1775
+LG+ V F C+EG+ L+G C+ ++ M A W+ PVC C P
Sbjct: 360 RLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSP 419
Query: 1776 N-PPAILNGRHTGTPFGDIPYGKEISYACDTHP-DRGMTFNLIGESS-----------IR 1822
N P N H + K I A + +RG +G+ +
Sbjct: 420 NFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILT 479
Query: 1823 CTSDP--------------QGNGVWSSPAPRC--ELSVPAACPHPPKIQNGHYIGGHVSL 1866
TS P Q +G SS + E +C P G G S
Sbjct: 480 GTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREG---SR 536
Query: 1867 YLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLFMN 1916
+ G T+ + C P + LVG+ I C WS K+ C F F N
Sbjct: 537 FHHGDTLKFECQPAFELVGQKAITCQKNNQWS-----AKKPGCVFSCFFN 581
Score = 45.1 bits (105), Expect = 7e-04
Identities = 155/722 (21%), Positives = 240/722 (33%), Gaps = 174/722 (24%)
Query: 1091 VTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV-ENGILV 1149
V + L SRG K+ + + + TS QVG+ G N C P + E G +
Sbjct: 305 VKKQIELKSRGVKL--MPSKDNSQKTSVLTQVGVSQGH-------NMCPDPGIPERGKRL 355
Query: 1150 SDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALN----KWEPELPSC-SRVC----QPP 1200
+ F L V+F C G+ ++G +R+ C ++ W P C +R+C + P
Sbjct: 356 GSD---FRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGP 412
Query: 1201 PEILHGEHTPSHQDN----------FSPGQEVFYSCEPGYDL-RGAASLHCTPQGDWSPE 1249
I+ + P DN +P + + + E +DL RG +L GD +
Sbjct: 413 SGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEE-FDLERGYDTL---TVGDGGQD 468
Query: 1250 APRCAV------KSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLV 1303
+ V S D + H L F+ GS S +
Sbjct: 469 GDQKTVLYILTGTSVPDLIVSTNHQMWLL-----------------FQTDGSGSS----L 507
Query: 1304 GMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLI 1363
G ++ S E C +P GR G+ +G + + C P F L+
Sbjct: 508 GFKA----SYEEIEQGSCGDPGIPAYGRREGS---RFHHGDTLKFECQP------AFELV 554
Query: 1364 GESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLN 1423
G+ I C N WS+ P C S F F SP+ + +P +
Sbjct: 555 GQKAITCQK----NNQWSAKKPGCVFSC---------FFNFTSPSGVVLSPNYPEDYGNH 601
Query: 1424 YEC------RP-GYFGKMFS-ISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQ 1475
C RP F+ I + ++D ++ P F+G Q
Sbjct: 602 LHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEA--PVLGTFSG-------NQ 652
Query: 1476 FGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNR 1535
S++ S RL + G N+T+ C P NG + +
Sbjct: 653 LPSSIT-SSGHVARLEFQTDHSTGKRGFNITF----TTFRHNECPDPGVPVNGKRFGD-- 705
Query: 1536 TSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPE 1595
S G+ +++ C G G Q G +I C K+ V VW+S RC +
Sbjct: 706 -SLQLGSSISFLCDEGFLGTQ-----GSETITCVLKEGSV-VWNSAVLRCEAPCGGHLTS 758
Query: 1596 VENAIRVPGNRSFF--TLTEIIRFRCQPGFVM----------VGSHTVQCQTNGRWGPKL 1643
I PG F+ L+ QPG+ + V T++ + + L
Sbjct: 759 PSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPL 818
Query: 1644 PHCSRVCQPPPEILHGEHTL--------SHQD---------------------------- 1667
Q P ++ + L SH D
Sbjct: 819 IGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQR 878
Query: 1668 ---NFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVL 1724
+F G V +SC+ Y L L C P WS P C C F+ Q G +L
Sbjct: 879 HGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEA-LCGGFI-QGSSGTIL 936
Query: 1725 LP 1726
P
Sbjct: 937 SP 938
Score = 40.4 bits (93), Expect = 0.018
Identities = 25/60 (41%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
Query: 1456 SCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLV-SGNNVTWDKKAPIC 1514
+CG P NG+ +T G V YSCN GF L G TC S N+ TWD P C
Sbjct: 138 TCGNPGRLPNGIQQGST-FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSC 196
Score = 38.1 bits (87), Expect = 0.089
Identities = 37/133 (27%), Positives = 49/133 (36%), Gaps = 17/133 (12%)
Query: 1007 PPDPVNGMVHVITDIQVGSRINYSCTT-GHRLIGHSSAECILSGNTAHWSTKPPICQRIP 1065
PP P N +T Q+ + I + TT RLI + G A + P
Sbjct: 86 PPQPENLRTR-LTGFQLPATIVSAATTLSLRLISDYAVSA--QGFHATYEVLPSHT---- 138
Query: 1066 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1125
CG P + NG F+ G V Y CNLG F L G + C + + W
Sbjct: 139 CGNPGRLPNG---IQQGSTFNLGDKVRYSCNLG------FFLEGHAVLTCHAGSENSATW 189
Query: 1126 SGPAPQCIIPNKC 1138
P P C + C
Sbjct: 190 DFPLPSCRADDAC 202
Score = 36.2 bits (82), Expect = 0.34
Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 9/67 (13%)
Query: 421 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 480
C +P +PNG G F G V Y+C+ F L G + + C + + + W
Sbjct: 139 CGNPGRLPNGIQQGS---TFNLGDKVRYSCN------LGFFLEGHAVLTCHAGSENSATW 189
Query: 481 SSPAPRC 487
P P C
Sbjct: 190 DFPLPSC 196
Score = 36.2 bits (82), Expect = 0.34
Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 9/67 (13%)
Query: 871 CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVW 930
C +P +PNG G F G V Y+C+ F L G + + C + + + W
Sbjct: 139 CGNPGRLPNGIQQGS---TFNLGDKVRYSCN------LGFFLEGHAVLTCHAGSENSATW 189
Query: 931 SSPAPRC 937
P P C
Sbjct: 190 DFPLPSC 196
Score = 35.8 bits (81), Expect = 0.44
Identities = 29/131 (22%), Positives = 49/131 (37%), Gaps = 18/131 (13%)
Query: 1289 GFRLKGSSVSHCVLVGMRSLWNNSVP---------VCEHIFCPNPPAILNGRHTGTPSGD 1339
GF+L + VS + +R + + +V V C NP + NG G+
Sbjct: 98 GFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRLPNGIQQGSTFN- 156
Query: 1340 IPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTP 1399
G ++ Y+C+ + F L G + + C + + W P P C G
Sbjct: 157 --LGDKVRYSCN------LGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGTLRG 208
Query: 1400 EQFPFASPTIP 1410
+ +SP P
Sbjct: 209 QSGIISSPHFP 219
Score = 33.9 bits (76), Expect = 1.7
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 2/67 (2%)
Query: 547 DVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL-SGNAAHWS 605
+V +C P NG+ T +G ++ YSC G L GH+ C S N+A W
Sbjct: 132 EVLPSHTCGNPGRLPNGIQQGST-FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWD 190
Query: 606 TKPPICQ 612
P C+
Sbjct: 191 FPLPSCR 197
Score = 33.9 bits (76), Expect = 1.7
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 2/67 (2%)
Query: 997 DVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECIL-SGNTAHWS 1055
+V +C P NG+ T +G ++ YSC G L GH+ C S N+A W
Sbjct: 132 EVLPSHTCGNPGRLPNGIQQGST-FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWD 190
Query: 1056 TKPPICQ 1062
P C+
Sbjct: 191 FPLPSCR 197
Score = 33.9 bits (76), Expect = 1.7
Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 5/59 (8%)
Query: 1928 YHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKCTSRTHDALIVGTLSGTIFFIL 1986
++ G VT C+ GYTL +C+ + +W L C +AL G + G+ IL
Sbjct: 883 FYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSC-----EALCGGFIQGSSGTIL 936
Score = 33.1 bits (74), Expect = 2.8
Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 103 SCRNPPDPVNGMVHVIKGIQF--GSQIKYSCTKGYRLIGSSSATCII-SGDTVIWDNETP 159
+C NP NG + +G F G +++YSC G+ L G + TC S ++ WD P
Sbjct: 138 TCGNPGRLPNG---IQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLP 194
Query: 160 IC 161
C
Sbjct: 195 SC 196
Score = 32.7 bits (73), Expect = 3.7
Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 7/58 (12%)
Query: 240 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK----WEPELPSC 293
P + NGI S F+L + V + C GF ++G + C A ++ W+ LPSC
Sbjct: 142 PGRLPNGI---QQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSC 196
Score = 32.7 bits (73), Expect = 3.7
Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 7/58 (12%)
Query: 690 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK----WEPELPSC 743
P + NGI S F+L + V + C GF ++G + C A ++ W+ LPSC
Sbjct: 142 PGRLPNGI---QQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSC 196
Score = 31.6 bits (70), Expect = 8.3
Identities = 20/63 (31%), Positives = 26/63 (41%), Gaps = 7/63 (11%)
Query: 1922 LEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDR----WDPPLAKCTSRTHDALIVGT 1977
++ ++ GD V C G+ LEG C A WD PL C + D GT
Sbjct: 149 IQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRA---DDACGGT 205
Query: 1978 LSG 1980
L G
Sbjct: 206 LRG 208
>gi|4502503 complement component 4 binding protein, alpha chain
precursor [Homo sapiens]
Length = 597
Score = 221 bits (563), Expect = 6e-57
Identities = 158/521 (30%), Positives = 229/521 (43%), Gaps = 54/521 (10%)
Query: 1394 GHCKTPEQFPFASPT-IPINDFEFPVGTSLNYECRPGYFGKMFS--ISCLENLVWSSVED 1450
G+C P FA+P I + + F GT+L Y C PGY + ++C + W
Sbjct: 48 GNCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWV-YNT 106
Query: 1451 NCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKK 1510
C K C P E NG V I TD FGS + +SC+EGF LIGS ++ C V V W
Sbjct: 107 FCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHP 166
Query: 1511 APICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTS 1570
P CEI+ C+PPP I NG +S + G VTY C + F L+G SI CT
Sbjct: 167 LPQCEIVKCKPPPDIRNGR-HSGEENFYAYGFSVTYSC------DPRFSLLGHASISCTV 219
Query: 1571 KDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHT 1630
+++ +GVW PP C C P+V + V G + + I F+CQ GFV+ GS
Sbjct: 220 ENETIGVWRPSPPTCEKIT-CRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSV 278
Query: 1631 VQCQTNGRWGPKLPHCS-RVCQPPPEILHGEHTL----SHQDNFSPGQEVFYSCEPSY-- 1683
+ C + +W P P C C P+I H + +D + G + Y C P Y
Sbjct: 279 IHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKP 338
Query: 1684 DLRGAASLHCTPQGDWSP----EAPRCTVKSCDDFLGQLPHGRVLLPLN---LQLGAKVS 1736
++ C W+P EA C ++ G++ R P N G ++S
Sbjct: 339 TTDEPTTVICQKNLRWTPYQGCEALCCPEPKLNN--GEITQHRKSRPANHCVYFYGDEIS 396
Query: 1737 FVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYG 1796
F C E R + W+ P C I C PP I +G + + +
Sbjct: 397 FSCHETSRFS-------AICQGDGTWSPRTPSCGDI-CNFPPKIAHGHYKQSSSYSF-FK 447
Query: 1797 KEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQN 1856
+EI Y CD + L+G++ + C+ WS+PAP+C+ A C P++ N
Sbjct: 448 EEIIYECD------KGYILVGQAKLSCSYSH-----WSAPAPQCK----ALC-RKPELVN 491
Query: 1857 GHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIW 1897
G + Y+ ++ CD GY +VG I C+ W
Sbjct: 492 GR-LSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSGNRTW 531
Score = 221 bits (562), Expect = 7e-57
Identities = 158/537 (29%), Positives = 244/537 (45%), Gaps = 52/537 (9%)
Query: 31 VVLLALPVAWGQCNAPEWLPFARPTNLT-DEFEFPIGTYLNYECRPGY--SGRPFSIICL 87
++ LP G C P L FA P ++T E F GT L Y C PGY S ++ C
Sbjct: 38 LIAALLPAVLGNCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCN 97
Query: 88 KNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCII 147
+ W C K CR+P + NG V + + FGSQI++SC++G+ LIGS+++ C +
Sbjct: 98 SDGEWV-YNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEV 156
Query: 148 SGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFH-YGSVVTYRCNPGSGGRKVFE 206
V W + P C+ + C PP I NG + ENF+ YG VTY C+P F
Sbjct: 157 QDRGVGWSHPLPQCEIVKCKPPPDIRNGR--HSGEENFYAYGFSVTYSCDPR------FS 208
Query: 207 LVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRC 266
L+G SI CT ++ +G+W P+P C P+V +G +VS +++ + + F+C
Sbjct: 209 LLGHASISCTVENETIGVWR-PSPPTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKC 267
Query: 267 QPGFVMKGPRRVKCQALNKWEPELPSCS-RVCQPPPDVLHAE----RTQRDKDNFSPGQE 321
Q GFV++G + C A +KW P P+C C PD+ HA +D + G
Sbjct: 268 QKGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTV 327
Query: 322 VFYSCEPGY--DLRGAASMRCTPQGDWSPAAPTCEVKSCDD---FMGQLLNGRVLFPVN- 375
+ Y C PGY ++ C W+P CE C + G++ R P N
Sbjct: 328 LRYRCHPGYKPTTDEPTTVICQKNLRWTP-YQGCEALCCPEPKLNNGEITQHRKSRPANH 386
Query: 376 --LQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHT 433
G ++ F C E ++ + + + W+ P C I C PP I +G +
Sbjct: 387 CVYFYGDEISFSCHE-------TSRFSAICQGDGTWSPRTPSCGDI-CNFPPKIAHGHYK 438
Query: 434 GKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHC 493
F F + + Y CD + L+G++ + C+ WS+PAP+C L C
Sbjct: 439 QSSSYSF-FKEEIIYECD------KGYILVGQAKLSCSYSH-----WSAPAPQCKAL--C 484
Query: 494 QAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCK 550
+ P+ + +L + P +++ + G P SITC N W C+
Sbjct: 485 RKPE-LVNGRLSVDKDQYVEPENVTIQCDSGYGVVG-PQSITCSGNRTWYPEVPKCE 539
Score = 202 bits (514), Expect = 3e-51
Identities = 151/529 (28%), Positives = 235/529 (44%), Gaps = 52/529 (9%)
Query: 489 ILGHCQAPDHFLFAK-LKTQTNASDFPIGTSLKYECRPEYYGRPFS--ITCLDNLVWSSP 545
+LG+C P FA + + F GT+LKY C P Y + +TC + W
Sbjct: 46 VLGNCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVY- 104
Query: 546 KDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWS 605
C K C+ P + NG V + TD+ GS+I +SC+ G LIG +++ C + WS
Sbjct: 105 NTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWS 164
Query: 606 TKPPICQRIPCGLPPTIANGDFISTNRENFH-YGSVVTYRCNPGSGGRKVFELVGEPSIY 664
P C+ + C PP I NG + ENF+ YG VTY C+P F L+G SI
Sbjct: 165 HPLPQCEIVKCKPPPDIRNGR--HSGEENFYAYGFSVTYSCDPR------FSLLGHASIS 216
Query: 665 CTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKG 724
CT ++ +G+W P+P C P+V +G +VS +++ + + F+CQ GFV++G
Sbjct: 217 CTVENETIGVWR-PSPPTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRG 275
Query: 725 PRRVKCQALNKWEPELPSCS-RVCQPPPDVLHAE----RTQRDKDNFSPGQEVFYSCEPG 779
+ C A +KW P P+C C PD+ HA +D + G + Y C PG
Sbjct: 276 SSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPG 335
Query: 780 Y--DLRGAASMRCTPQGDWSPAAPTCEVKSCDD---FMGQLLNGRVLFPVN---LQLGAK 831
Y ++ C W+P CE C + G++ R P N G +
Sbjct: 336 YKPTTDEPTTVICQKNLRWTP-YQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDE 394
Query: 832 VDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFP 891
+ F C E ++ + + + W+ P C I C PP I +G + F
Sbjct: 395 ISFSCHE-------TSRFSAICQGDGTWSPRTPSCGDI-CNFPPKIAHGHYKQSSSYSF- 445
Query: 892 FGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLF 951
F + + Y CD + L+G++ + C+ WS+PAP+C L C+ P+ +
Sbjct: 446 FKEEIIYECD------KGYILVGQAKLSCSYSH-----WSAPAPQCKAL--CRKPE-LVN 491
Query: 952 AKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNLVWSSPKDVCK 1000
+L + P +++ + G P SITC N W C+
Sbjct: 492 GRLSVDKDQYVEPENVTIQCDSGYGVVG-PQSITCSGNRTWYPEVPKCE 539
Score = 179 bits (453), Expect = 3e-44
Identities = 148/535 (27%), Positives = 226/535 (42%), Gaps = 62/535 (11%)
Query: 1456 SCGPPPE-PFNGMVHIN-TDTQF--GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKA 1511
+CGPPP F + I T+T+F G+T+ Y+C G+ + S ST L ++ W
Sbjct: 49 NCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGY--VRSHSTQTLTCNSDGEWVYNT 106
Query: 1512 PICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSK 1571
C C P + NG SF G+ + + C G F L+G + C +
Sbjct: 107 -FCIYKRCRHPGELRNGQVEIKTDLSF--GSQIEFSCSEG------FFLIGSTTSRCEVQ 157
Query: 1572 DDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTV 1631
D VG WS P P+C P++ N R G +F+ + + C P F ++G ++
Sbjct: 158 DRGVG-WSHPLPQCEIVKCKPPPDIRNG-RHSGEENFYAYGFSVTYSCDPRFSLLGHASI 215
Query: 1632 QC----QTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRG 1687
C +T G W P P C ++ P++ HGE ++ + + C+ + LRG
Sbjct: 216 SCTVENETIGVWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRG 275
Query: 1688 AASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHG------RVLLPLNLQLGAKVSFVCDE 1741
++ +HC W+P P C SC + L +PH R +G + + C
Sbjct: 276 SSVIHCDADSKWNPSPPACEPNSCIN-LPDIPHASWETYPRPTKEDVYVVGTVLRYRCHP 334
Query: 1742 GFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHT----GTPFGDIPY-- 1795
G+ K + + K L + CE + CP P + NG T P Y
Sbjct: 335 GY--KPTTDEPTTVICQKNLRWTPYQGCEALCCPEPK-LNNGEITQHRKSRPANHCVYFY 391
Query: 1796 GKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQ 1855
G EIS++C + R ++ QG+G WS P C C PPKI
Sbjct: 392 GDEISFSC--------------HETSRFSAICQGDGTWSPRTPSCG----DICNFPPKIA 433
Query: 1856 NGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCSFPLFM 1915
+GHY + I Y CD GY+LVG+ + C+ WS CK + C P +
Sbjct: 434 HGHYKQSSSYSFFKEEII-YECDKGYILVGQAKLSCS-YSHWSAPAPQCKAL-CRKPELV 490
Query: 1916 NG-ISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKCTSRT 1969
NG +S + K Y + VT++C+ GY + G C + W P + KC T
Sbjct: 491 NGRLSVD---KDQYVEPENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKCEWET 542
Score = 178 bits (451), Expect = 5e-44
Identities = 146/541 (26%), Positives = 237/541 (43%), Gaps = 72/541 (13%)
Query: 740 LPSCSRVCQPPPDVLHAERTQ--RDKDNFSPGQEVFYSCEPGY-DLRGAASMRCTPQGDW 796
LP+ C PPP + A + F G + Y+C PGY ++ C G+W
Sbjct: 43 LPAVLGNCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEW 102
Query: 797 SPAAPTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGME 856
C K C G+L NG+V +L G++++F C EGF L GS+ S C +
Sbjct: 103 VYNT-FCIYKRCRH-PGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRG 160
Query: 857 SLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGES 916
W+ +P CE + C PP I NGRH+G+ + +G +V Y+CDP F L+G +
Sbjct: 161 VGWSHPLPQCEIVKCKPPPDIRNGRHSGEE-NFYAYGFSVTYSCDPR------FSLLGHA 213
Query: 917 TIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDF-PI---GTSLKYE 972
+I CT + + GVW P C + C+ PD + S F PI ++ ++
Sbjct: 214 SISCTVENETIGVWRPSPPTCEKI-TCRKPD------VSHGEMVSGFGPIYNYKDTIVFK 266
Query: 973 CRPEYYGRPFS-ITCLDNLVWSSPKDVCKRKSC-----------KTPPDPVNGMVHVITD 1020
C+ + R S I C + W+ C+ SC +T P P V+V
Sbjct: 267 CQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYV--- 323
Query: 1021 IQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFIST 1080
VG+ + Y C G++ I N W T C+ + C P + NG+ I+
Sbjct: 324 --VGTVLRYRCHPGYKPTTDEPTTVICQKN-LRW-TPYQGCEALCCP-EPKLNNGE-ITQ 377
Query: 1081 NREN-------FHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCI 1133
+R++ + YG +++ C+ SR S C + G WS P C
Sbjct: 378 HRKSRPANHCVYFYGDEISFSCHETSRF----------SAICQGD----GTWSPRTPSC- 422
Query: 1134 IPNKCT-PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPS 1192
+ C PP + +G + F E++ + C G+++ G ++ C + + W P
Sbjct: 423 -GDICNFPPKIAHGHYKQSSSYSFFKEEII-YECDKGYILVGQAKLSC-SYSHWSAPAPQ 479
Query: 1193 CSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPR 1252
C +C+ PE+++G + +D + + V C+ GY + G S+ C+ W PE P+
Sbjct: 480 CKALCR-KPELVNGRLSVD-KDQYVEPENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPK 537
Query: 1253 C 1253
C
Sbjct: 538 C 538
Score = 177 bits (450), Expect = 7e-44
Identities = 143/530 (26%), Positives = 220/530 (41%), Gaps = 107/530 (20%)
Query: 1190 LPSCSRVCQPPPEILHGE--HTPSHQDNFSPGQEVFYSCEPGY-DLRGAASLHCTPQGDW 1246
LP+ C PPP + + F G + Y+C PGY +L C G+W
Sbjct: 43 LPAVLGNCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEW 102
Query: 1247 SPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMR 1306
C K C G+L +G+V +L G+++ F C EGF L GS+ S C +
Sbjct: 103 VYNT-FCIYKRCRH-PGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRG 160
Query: 1307 SLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGES 1366
W++ +P CE + C PP I NGRH+G YG ++Y+CDP F+L+G +
Sbjct: 161 VGWSHPLPQCEIVKCKPPPDIRNGRHSG-EENFYAYGFSVTYSCDPR------FSLLGHA 213
Query: 1367 TIRCTSDPHGNGVWSSPAPRCEL------SVRAG-------------------------- 1394
+I CT + GVW P CE V G
Sbjct: 214 SISCTVENETIGVWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVL 273
Query: 1395 ------HCKTPEQF----PFASPTIPINDFEFP-----------------VGTSLNYECR 1427
HC ++ P P IN + P VGT L Y C
Sbjct: 274 RGSSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCH 333
Query: 1428 PGY---FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQ--------F 1476
PGY + ++ C +NL W+ + C C P P+ NG + + ++ +
Sbjct: 334 PGYKPTTDEPTTVICQKNLRWTPYQ-GCEALCC-PEPKLNNGEITQHRKSRPANHCVYFY 391
Query: 1477 GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRT 1536
G +++SC+E R S C G TW + P C I C PP I++G + ++
Sbjct: 392 GDEISFSCHETSRF----SAICQGDG---TWSPRTPSCGDI-CNFPPKIAHGHYKQSSSY 443
Query: 1537 SFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEV 1596
SF ++ Y+C G + LVG+ + C+ WS+P P+C + C PE+
Sbjct: 444 SFFKEEII-YECDKG------YILVGQAKLSCSYSH-----WSAPAPQCKAL--CRKPEL 489
Query: 1597 ENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHC 1646
N R+ ++ + E + +C G+ +VG ++ C N W P++P C
Sbjct: 490 VNG-RLSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKC 538
Score = 151 bits (381), Expect = 7e-36
Identities = 131/521 (25%), Positives = 209/521 (40%), Gaps = 74/521 (14%)
Query: 1019 TDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFI 1078
T + G+ + Y+C G+ + S + + + W C C P + NG
Sbjct: 69 TRFKTGTTLKYTCLPGY--VRSHSTQTLTCNSDGEWVYNT-FCIYKRCRHPGELRNGQV- 124
Query: 1079 STNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKC 1138
+ + +GS + + C+ G F L+G + C D VG WS P PQC I
Sbjct: 125 -EIKTDLSFGSQIEFSCSEG------FFLIGSTTSRCEVQDRGVG-WSHPLPQCEIVKCK 176
Query: 1139 TPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNK----WEPELPSCS 1194
PP++ NG S + ++ V + C P F + G + C N+ W P P+C
Sbjct: 177 PPPDIRNG-RHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCE 235
Query: 1195 RVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCA 1254
++ P++ HGE ++ + + C+ G+ LRG++ +HC W+P P C
Sbjct: 236 KITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACE 295
Query: 1255 VKSCDDFLGQLPHGR-VLFPLNLQ-----LGAKVSFVCDEGFRLKGSSVSHCVLVGMRSL 1308
SC + L +PH +P + +G + + C G+ K ++ ++ ++L
Sbjct: 296 PNSCIN-LPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGY--KPTTDEPTTVICQKNL 352
Query: 1309 WNNSVPVCEHIFCPNPPAILNGRHT----GTPSGDIP--YGKEISYTCDPHPDRGMTFNL 1362
CE + CP P + NG T P+ YG EIS++C
Sbjct: 353 RWTPYQGCEALCCPE-PKLNNGEITQHRKSRPANHCVYFYGDEISFSC------------ 399
Query: 1363 IGESTIRCTSDPHGNGVWSSPAPRC------ELSVRAGHCKTPEQFPFASPTIPINDFEF 1416
T R ++ G+G WS P C + GH K + F I
Sbjct: 400 --HETSRFSAICQGDGTWSPRTPSCGDICNFPPKIAHGHYKQSSSYSFFKEEI------- 450
Query: 1417 PVGTSLNYECRPGY-FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQ 1475
YEC GY +SC + WS+ C K+ PE NG + ++ D
Sbjct: 451 ------IYECDKGYILVGQAKLSCSYS-HWSAPAPQC--KALCRKPELVNGRLSVDKDQY 501
Query: 1476 F-GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICE 1515
V C+ G+ ++G S TC SGN TW + P CE
Sbjct: 502 VEPENVTIQCDSGYGVVGPQSITC--SGNR-TWYPEVPKCE 539
Score = 134 bits (337), Expect = 9e-31
Identities = 96/328 (29%), Positives = 141/328 (42%), Gaps = 24/328 (7%)
Query: 1643 LPHCSRVCQPPPEILHG---EHTLSHQDNFSPGQEVFYSCEPSY-DLRGAASLHCTPQGD 1698
LP C PPP + + TL+ + F G + Y+C P Y +L C G+
Sbjct: 43 LPAVLGNCGPPPTLSFAAPMDITLT-ETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGE 101
Query: 1699 WSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGM 1758
W C K C G+L +G+V + +L G+++ F C EGF L G + S C +
Sbjct: 102 WVYNT-FCIYKRCRH-PGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDR 159
Query: 1759 KALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGE 1818
W+ +P CE + C PP I NGRH+G YG ++Y+CD F+L+G
Sbjct: 160 GVGWSHPLPQCEIVKCKPPPDIRNGRHSGEE-NFYAYGFSVTYSCDPR------FSLLGH 212
Query: 1819 SSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICD 1878
+SI CT + + GVW P CE C P + +G + G +Y TI + C
Sbjct: 213 ASISCTVENETIGVWRPSPPTCE---KITC-RKPDVSHGEMVSGFGPIYNYKDTIVFKCQ 268
Query: 1879 PGYLLVGKGFIFCTDQGIWSQLDHYCKEVNC----SFPLFMNGISKELEMKKVYHYGDYV 1934
G++L G I C W+ C+ +C P + VY G +
Sbjct: 269 KGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVL 328
Query: 1935 TLKCEDGY--TLEGSPWSQCQADDRWDP 1960
+C GY T + CQ + RW P
Sbjct: 329 RYRCHPGYKPTTDEPTTVICQKNLRWTP 356
>gi|157419154 selectin P precursor [Homo sapiens]
Length = 830
Score = 192 bits (488), Expect = 3e-48
Identities = 163/631 (25%), Positives = 245/631 (38%), Gaps = 79/631 (12%)
Query: 1166 CQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYS 1225
C PGF GP +C+ + + C + P +++ H NFS + +
Sbjct: 185 CYPGFY--GP---ECEYVRE-------CGELELPQHVLMNCSHPLG---NFSFNSQCSFH 229
Query: 1226 CEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLN----LQLGAK 1281
C GY + G + L C G W+ + P+C C ++P + L+ Q +
Sbjct: 230 CTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPL--KIPERGNMTCLHSAKAFQHQSS 287
Query: 1282 VSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGT-PSGDI 1340
SF C+EGF L G V C G+ W PVC+ + C + A G P
Sbjct: 288 CSFSCEEGFALVGPEVVQCTASGV---WTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAF 344
Query: 1341 PYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPE 1400
YG + C P + + G +RC H WS+P P CE A C+ E
Sbjct: 345 AYGSSCKFECQPG------YRVRGLDMLRCIDSGH----WSAPLPTCE----AISCEPLE 390
Query: 1401 QFPFASPTIPINDFEFPVGTSLNYECRPGYFGKMFSISCLENL-VWSSVEDNCRRKSCGP 1459
S + F T+ ++ C G+ + I +NL W++ C+ C
Sbjct: 391 SPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQD 450
Query: 1460 PPEPFNGMVHINTDTQFG-----STVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPIC 1514
P P +N FG S +++CNEG L+G+ CL +GN W+ P C
Sbjct: 451 LPVP--NEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGN---WNSVPPEC 505
Query: 1515 EIISCEPPPTISNGDFYSNNRT-SFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDD 1573
+ I C P + NG S + + C G + L G + CT
Sbjct: 506 QAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEG------YSLSGPERLDCTRS-- 557
Query: 1574 QVGVWSSPPPRC--ISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTV 1631
G W+ PP C I + APE + ++ R F + F C GF + G + V
Sbjct: 558 --GRWTDSPPMCEAIKCPELFAPE-QGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNV 614
Query: 1632 QCQTNGRWGPKLPHCSRVC-------QPPPEILHGEHTL---SHQDNFSPGQEVFYSCEP 1681
+C T+GRW P C + Q P G+ T+ H F ++ C
Sbjct: 615 ECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNA 674
Query: 1682 SYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPL--NLQLGAKVSFVC 1739
+ L G ++L C P G W+ P C C + P L N G+ SF C
Sbjct: 675 GFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHC 734
Query: 1740 DEGFRLKGRSASHCVLAGMKALWNSSVPVCE 1770
EG L G + + C G W+++VP C+
Sbjct: 735 LEGQLLNGSAQTACQENGH---WSTTVPTCQ 762
Score = 191 bits (484), Expect = 8e-48
Identities = 165/633 (26%), Positives = 249/633 (39%), Gaps = 65/633 (10%)
Query: 1356 RGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFE 1415
+G IG T C +G P CE G + P Q + + P+ +F
Sbjct: 171 QGECLETIGNYTCSCYPGFYG--------PECEYVRECGELELP-QHVLMNCSHPLGNFS 221
Query: 1416 FPVGTSLNYECRPGY-FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNG---MVHIN 1471
F + ++ C GY + CL + +W++ C C P P G +H
Sbjct: 222 F--NSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSA 279
Query: 1472 TDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFY 1531
Q S+ ++SC EGF L+G C SG W AP+C+ + C+ S G
Sbjct: 280 KAFQHQSSCSFSCEEGFALVGPEVVQCTASG---VWTAPAPVCKAVQCQHLEAPSEGTMD 336
Query: 1532 S-NNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRC--IST 1588
+ T+F G+ ++C G + + G + C G WS+P P C IS
Sbjct: 337 CVHPLTAFAYGSSCKFECQPG------YRVRGLDMLRCIDS----GHWSAPLPTCEAISC 386
Query: 1589 NKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSR 1648
+P + P R+F T FRC GF++ G+ V+C G+W P C
Sbjct: 387 EPLESPVHGSMDCSPSLRAFQYDTNC-SFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQA 445
Query: 1649 V-CQPPPEILHGEHTLSHQDNFSPGQEVF-YSCEPSYDLRGAASLHCTPQGDWSPEAPRC 1706
+ CQ P SH Q V ++C L GA+ L C G+W+ P C
Sbjct: 446 LQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPEC 505
Query: 1707 TVKSCDDFLG-QLPHGRVLLPL-NLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNS 1764
C L Q + PL + + F+CDEG+ L G C +G W
Sbjct: 506 QAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGR---WTD 562
Query: 1765 SVPVCEQIFCPNPPAILNGR-HTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRC 1823
S P+CE I CP A G G+ G ++CD F L G +++ C
Sbjct: 563 SPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNG------FKLEGPNNVEC 616
Query: 1824 TSDPQGNGVWSSPAPRCE--LSVPAACPHPPKI----QNGHYIGGHVSLYLPGMTISYIC 1877
T+ +G WS+ P C+ S+P P + Q Y H + T + C
Sbjct: 617 TT----SGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGC 672
Query: 1878 DPGYLLVGKGFIFCTDQGIWSQLDHYCKEVNCS-----FPLFMNGISKELEMKKVYHYGD 1932
+ G+ L+G + C G W+ + C+ V CS P+ MN + + + YG
Sbjct: 673 NAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSN----LWGNFSYGS 728
Query: 1933 YVTLKCEDGYTLEGSPWSQCQADDRWDPPLAKC 1965
+ C +G L GS + CQ + W + C
Sbjct: 729 ICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC 761
Score = 181 bits (458), Expect = 8e-45
Identities = 158/591 (26%), Positives = 235/591 (39%), Gaps = 76/591 (12%)
Query: 1084 NFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 1143
NF + S ++ C G +++ G + C ++ GIW+ PQC+ +C P +
Sbjct: 219 NFSFNSQCSFHCTDG------YQVNGPSKLECLAS----GIWTNKPPQCLAA-QCPPLKI 267
Query: 1144 -ENGILVS-DNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPP 1200
E G + + F F C+ GF + GP V+C A W P C V CQ
Sbjct: 268 PERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHL 327
Query: 1201 PEILHGEHTPSHQ-DNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCD 1259
G H F+ G + C+PGY +RG L C G WS P C SC+
Sbjct: 328 EAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCE 387
Query: 1260 DFLGQLPHGRVLFPLNL---QLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVC 1316
L HG + +L Q SF C EGF L+G+ + C +G W PVC
Sbjct: 388 P-LESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQ---WTAPAPVC 443
Query: 1317 EHIFCPNPPAILNGR-HTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPH 1375
+ + C + P R + P G Y S+TC + G+ L+G S ++C +
Sbjct: 444 QALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTC----NEGLL--LVGASVLQCLA--- 494
Query: 1376 GNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTS-----LNYECRPGY 1430
G W+S P C+ A C P SP P+G+S + C GY
Sbjct: 495 -TGNWNSVPPECQ----AIPCT-----PLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGY 544
Query: 1431 -FGKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINT---DTQFGSTVNYSCNE 1486
+ C + W+ C C P G + + + GST ++SC+
Sbjct: 545 SLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDN 604
Query: 1487 GFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPP--------TISNGDFYSNNRT-S 1537
GF+L G + C SG W P C+ I+ P P T G Y + +
Sbjct: 605 GFKLEGPNNVECTTSGR---WSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGT 661
Query: 1538 FHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVE 1597
F T + C+ G F L+G+ ++ C G W++ P C + KC+ V
Sbjct: 662 FGFNTTCYFGCNAG------FTLIGDSTLSCRPS----GQWTAVTPACRAV-KCSELHVN 710
Query: 1598 NAIRVPGNRSF--FTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHC 1646
I + + + F+ I F C G ++ GS CQ NG W +P C
Sbjct: 711 KPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC 761
Score = 177 bits (449), Expect = 9e-44
Identities = 150/593 (25%), Positives = 229/593 (38%), Gaps = 83/593 (13%)
Query: 184 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 243
NF + S ++ C G +++ G + C ++ GIW+ PQC+ +C P +
Sbjct: 219 NFSFNSQCSFHCTDG------YQVNGPSKLECLAS----GIWTNKPPQCLAA-QCPPLKI 267
Query: 244 -ENGILVS-DNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPP 300
E G + + F F C+ GF + GP V+C A W P C V CQ
Sbjct: 268 PERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQ-- 325
Query: 301 PDVLHAERTQRDKDN-------FSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 353
H E + F+ G + C+PGY +RG +RC G WS PTC
Sbjct: 326 ----HLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTC 381
Query: 354 EVKSCDDFMGQLLNGRVLFPV--NLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNS 411
E SC+ + P Q F C EGF L+G+ C G W +
Sbjct: 382 EAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQ---WTA 438
Query: 412 SVPVCEQIFCPSPPVIPNGR-HTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRC 470
PVC+ + C PV R + P F + ++TC+ L+G S ++C
Sbjct: 439 PAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCN------EGLLLVGASVLQC 492
Query: 471 TSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTS-----LKYECRP 525
+ G W+S P CQA + T P+G+S ++ C
Sbjct: 493 LA----TGNWNSVPP------ECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDE 542
Query: 526 EY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVIT---DIQVGSRINYSC 581
Y P + C + W+ +C+ C P G + + VGS ++SC
Sbjct: 543 GYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSC 602
Query: 582 TTGHRLIGHSSAECILSGNAAHWSTKPPICQRI--------PCGLPPTIANGDFISTNRE 633
G +L G ++ EC SG WS PP C+ I C T G +
Sbjct: 603 DNGFKLEGPNNVECTTSG---RWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHP 659
Query: 634 -NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPN 692
F + + + CN G F L+G+ ++ C + G W+ P C KC+ +
Sbjct: 660 GTFGFNTTCYFGCNAG------FTLIGDSTLSCRPS----GQWTAVTPACRAV-KCSELH 708
Query: 693 VENGILV--SDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC 743
V I + S+ FS + F C G ++ G + CQ W +P+C
Sbjct: 709 VNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC 761
Score = 177 bits (449), Expect = 9e-44
Identities = 150/593 (25%), Positives = 229/593 (38%), Gaps = 83/593 (13%)
Query: 634 NFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNV 693
NF + S ++ C G +++ G + C ++ GIW+ PQC+ +C P +
Sbjct: 219 NFSFNSQCSFHCTDG------YQVNGPSKLECLAS----GIWTNKPPQCLAA-QCPPLKI 267
Query: 694 -ENGILVS-DNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPP 750
E G + + F F C+ GF + GP V+C A W P C V CQ
Sbjct: 268 PERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQ-- 325
Query: 751 PDVLHAERTQRDKDN-------FSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 803
H E + F+ G + C+PGY +RG +RC G WS PTC
Sbjct: 326 ----HLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTC 381
Query: 804 EVKSCDDFMGQLLNGRVLFPV--NLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNS 861
E SC+ + P Q F C EGF L+G+ C G W +
Sbjct: 382 EAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQ---WTA 438
Query: 862 SVPVCEQIFCPSPPVIPNGR-HTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRC 920
PVC+ + C PV R + P F + ++TC+ L+G S ++C
Sbjct: 439 PAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCN------EGLLLVGASVLQC 492
Query: 921 TSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTS-----LKYECRP 975
+ G W+S P CQA + T P+G+S ++ C
Sbjct: 493 LA----TGNWNSVPP------ECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDE 542
Query: 976 EY-YGRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVIT---DIQVGSRINYSC 1031
Y P + C + W+ +C+ C P G + + VGS ++SC
Sbjct: 543 GYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSC 602
Query: 1032 TTGHRLIGHSSAECILSGNTAHWSTKPPICQRI--------PCGLPPTIANGDFISTNRE 1083
G +L G ++ EC SG WS PP C+ I C T G +
Sbjct: 603 DNGFKLEGPNNVECTTSG---RWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHP 659
Query: 1084 -NFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPN 1142
F + + + CN G F L+G+ ++ C + G W+ P C KC+ +
Sbjct: 660 GTFGFNTTCYFGCNAG------FTLIGDSTLSCRPS----GQWTAVTPACRAV-KCSELH 708
Query: 1143 VENGILV--SDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC 1193
V I + S+ FS + F C G ++ G + CQ W +P+C
Sbjct: 709 VNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTC 761
Score = 176 bits (446), Expect = 2e-43
Identities = 157/596 (26%), Positives = 242/596 (40%), Gaps = 75/596 (12%)
Query: 1016 HVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANG 1075
H + + S+ ++ CT G+++ G S EC+ SG W+ KPP C C G
Sbjct: 215 HPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASG---IWTNKPPQCLAAQCPPLKIPERG 271
Query: 1076 DFIST-NRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC-I 1133
+ + + F + S ++ C G F LVG + CT++ G+W+ PAP C
Sbjct: 272 NMTCLHSAKAFQHQSSCSFSCEEG------FALVGPEVVQCTAS----GVWTAPAPVCKA 321
Query: 1134 IPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC 1193
+ + E + + F+ +F CQPG+ ++G ++C W LP+C
Sbjct: 322 VQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTC 381
Query: 1194 SRV-CQPPPEILHG--EHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEA 1250
+ C+P +HG + +PS + F + C G+ LRGA + C G W+ A
Sbjct: 382 EAISCEPLESPVHGSMDCSPSLR-AFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPA 440
Query: 1251 PRCAVKSCDDF-LGQLPHGRVLFPLN-LQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSL 1308
P C C D + P + + SF C+EG L G+SV C+ G
Sbjct: 441 PVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGN--- 497
Query: 1309 WNNSVPVCEHIFCPNPPAILNGRHTGT-PSGDIPYGKEISYTCDPHPDRGMTFNLIGEST 1367
WN+ P C+ I C + NG T P G Y + CD ++L G
Sbjct: 498 WNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDE------GYSLSGPER 551
Query: 1368 IRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDF--EFPVGTSLNYE 1425
+ CT +G W+ P CE K PE F ++ +D EF VG++ ++
Sbjct: 552 LDCTR----SGRWTDSPPMCEA------IKCPELFAPEQGSLDCSDTRGEFNVGSTCHFS 601
Query: 1426 CRPGY-FGKMFSISCLENLVWSSVEDNCRRKSCGPPP--------EPFNGMV---HINTD 1473
C G+ ++ C + WS+ C+ + P P P G + H
Sbjct: 602 CDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGT 661
Query: 1474 TQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEP----PPTISNGD 1529
F +T + CN GF LIG + +C SG W P C + C P N
Sbjct: 662 FGFNTTCYFGCNAGFTLIGDSTLSCRPSGQ---WTAVTPACRAVKCSELHVNKPIAMN-- 716
Query: 1530 FYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRC 1585
SN +F G++ ++ C G QL L G C + G WS+ P C
Sbjct: 717 -CSNLWGNFSYGSICSFHCLEG----QL--LNGSAQTAC----QENGHWSTTVPTC 761
Score = 175 bits (443), Expect = 5e-43
Identities = 170/676 (25%), Positives = 268/676 (39%), Gaps = 114/676 (16%)
Query: 1225 SCEPGYDLRGAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSF 1284
SC PG+ G + G+ E P+ + +C LG N ++ SF
Sbjct: 184 SCYPGF--YGPECEYVRECGEL--ELPQHVLMNCSHPLG-----------NFSFNSQCSF 228
Query: 1285 VCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGD-IPYG 1343
C +G+++ G S C+ G +W N P C CP G T S +
Sbjct: 229 HCTDGYQVNGPSKLECLASG---IWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQ 285
Query: 1344 KEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFP 1403
S++C+ F L+G ++CT+ +GVW++PAP C+ +V+ H + P +
Sbjct: 286 SSCSFSCEEG------FALVGPEVVQCTA----SGVWTAPAPVCK-AVQCQHLEAPSEGT 334
Query: 1404 FASPTIPINDFEFPVGTSLNYECRPGYFGK-MFSISCLENLVWSSVEDNCRRKSCGPPPE 1462
P+ F + G+S +EC+PGY + + + C+++ WS+ C SC P
Sbjct: 335 MDC-VHPLTAFAY--GSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLES 391
Query: 1463 PFNGMVHINTDT---QFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISC 1519
P +G + + Q+ + ++ C EGF L G+ C N W AP+C+ + C
Sbjct: 392 PVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRC---DNLGQWTAPAPVCQALQC 448
Query: 1520 EPPPTISNGDFY-SNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVW 1578
+ P + S+ +F +V ++ C+ G LVG + C + G W
Sbjct: 449 QDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEG------LLLVGASVLQCLA----TGNW 498
Query: 1579 SSPPPRC--ISTNKCTAPE--VENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQ 1634
+S PP C I +P+ ++ G+ S+ + + I C G+ + G + C
Sbjct: 499 NSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFI---CDEGYSLSGPERLDCT 555
Query: 1635 TNGRWGPKLPHCSRVCQPPPEILHGEH-TLSHQDN---FSPGQEVFYSCEPSYDLRGAAS 1690
+GRW P C + PE+ E +L D F+ G +SC+ + L G +
Sbjct: 556 RSGRWTDSPPMCEAI--KCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNN 613
Query: 1691 LHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVS-------------- 1736
+ CT G WS P C + LP V P G
Sbjct: 614 VECTTSGRWSATPPTCKG------IASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTT 667
Query: 1737 --FVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCP----NPPAILNGRHTGTPF 1790
F C+ GF L G S C +G W + P C + C N P +N + +
Sbjct: 668 CYFGCNAGFTLIGDSTLSCRPSGQ---WTAVTPACRAVKCSELHVNKPIAMNCSNL---W 721
Query: 1791 GDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPH 1850
G+ YG C H G N G + C Q NG WS+ P C+
Sbjct: 722 GNFSYGS----ICSFHCLEGQLLN--GSAQTAC----QENGHWSTTVPTCQAG------- 764
Query: 1851 PPKIQNG-HYIGGHVS 1865
P IQ Y GG V+
Sbjct: 765 PLTIQEALTYFGGAVA 780
Score = 174 bits (441), Expect = 8e-43
Identities = 150/625 (24%), Positives = 231/625 (36%), Gaps = 104/625 (16%)
Query: 230 PQCIIPNKCTPPNVENGILVSDNRSL--FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWE 287
P+C +C + +L++ + L FS N F C G+ + GP +++C A W
Sbjct: 192 PECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWT 251
Query: 288 PELPSCSRVCQPPPDV--------LHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMR 339
+ P C PP + LH+ + + + + S +SCE G+ L G ++
Sbjct: 252 NKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCS------FSCEEGFALVGPEVVQ 305
Query: 340 CTPQGDWSPAAPTCEVKSCDDFMGQLLNGR-VLFPVN-LQLGAKVDFVCDEGFQLKGSSA 397
CT G W+ AP C+ C + P+ G+ F C G++++G
Sbjct: 306 CTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDM 365
Query: 398 SYCVLAGMESLWNSSVPVCEQIFC-PSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDR 456
C+ +G W++ +P CE I C P + L F + ++ C
Sbjct: 366 LRCIDSGH---WSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRC------ 416
Query: 457 GTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIG 516
F L G +RC + G W++PAP C L CQ D P+
Sbjct: 417 AEGFMLRGADIVRCDN----LGQWTAPAPVCQAL-QCQ-----------------DLPVP 454
Query: 517 TSLKYECRPEY----YGRPFSITCLDNLV--------------WSSPKDVCKRKSCKTPP 558
+ C + Y S TC + L+ W+S C+ C
Sbjct: 455 NEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLL 514
Query: 559 DPVNGMVHVITDI---QVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIP 615
P NG + + + S + C G+ L G +C SG W+ PP+C+ I
Sbjct: 515 SPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGR---WTDSPPMCEAIK 571
Query: 616 CGLPPTIANGDF-ISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGI 674
C G S R F+ GS + C+ G F+L G ++ CT++ G
Sbjct: 572 CPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNG------FKLEGPNNVECTTS----GR 621
Query: 675 WSGPAPQCIIPNKCTPPNVENGILVSDNRSL---------FSLNEVVEFRCQPGFVMKGP 725
WS P C P V+ L + + F N F C GF + G
Sbjct: 622 WSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGD 681
Query: 726 RRVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDK-----DNFSPGQEVFYSCEPG 779
+ C+ +W P+C V C LH + NFS G + C G
Sbjct: 682 STLSCRPSGQWTAVTPACRAVKCSE----LHVNKPIAMNCSNLWGNFSYGSICSFHCLEG 737
Query: 780 YDLRGAASMRCTPQGDWSPAAPTCE 804
L G+A C G WS PTC+
Sbjct: 738 QLLNGSAQTACQENGHWSTTVPTCQ 762
Score = 169 bits (429), Expect = 2e-41
Identities = 156/601 (25%), Positives = 234/601 (38%), Gaps = 88/601 (14%)
Query: 116 HVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNG 175
H + F SQ + CT GY++ G S C+ SG IW N+ P C C G
Sbjct: 215 HPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASG---IWTNKPPQCLAAQCPPLKIPERG 271
Query: 176 DFIST-NRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC-I 233
+ + + F + S ++ C G F LVG + CT++ G+W+ PAP C
Sbjct: 272 NMTCLHSAKAFQHQSSCSFSCEEG------FALVGPEVVQCTAS----GVWTAPAPVCKA 321
Query: 234 IPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSC 293
+ + E + + F+ +F CQPG+ ++G ++C W LP+C
Sbjct: 322 VQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTC 381
Query: 294 SRV-CQPPPDVLHAERTQRDKDNFSPGQEVF-------YSCEPGYDLRGAASMRCTPQGD 345
+ C+P +H + SP F + C G+ LRGA +RC G
Sbjct: 382 EAISCEPLESPVHGSM------DCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQ 435
Query: 346 WSPAAPTCEVKSCDDF-MGQLLNGRVLFPVN-LQLGAKVDFVCDEGFQLKGSSASYCVLA 403
W+ AP C+ C D + P + + F C+EG L G+S C+
Sbjct: 436 WTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLAT 495
Query: 404 GMESLWNSSVPVCEQIFCPSPPVIP-NGRHT-GKPLEVFPFGKTVNYTCDPHPDRGTSFD 461
G WNS P C+ I C +P + P NG T +PL + T + CD +
Sbjct: 496 GN---WNSVPPECQAIPC-TPLLSPQNGTMTCVQPLGSSSYKSTCQFICD------EGYS 545
Query: 462 LIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASD----FPIGT 517
L G + CT +G W+ P C + + P+ LFA + + SD F +G+
Sbjct: 546 LSGPERLDCTR----SGRWTDSPPMCEAI---KCPE--LFAPEQGSLDCSDTRGEFNVGS 596
Query: 518 SLKYECRPEY-YGRPFSITCLDNLVWSSPKDVCK--------RKSCKTPPDPVNGMV--- 565
+ + C + P ++ C + WS+ CK C P G +
Sbjct: 597 TCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCR 656
Query: 566 HVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCG----LPPT 621
H + + C G LIG S+ C SG W+ P C+ + C P
Sbjct: 657 HHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSG---QWTAVTPACRAVKCSELHVNKPI 713
Query: 622 IANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQ 681
N S NF YGS+ ++ C G L G C N G WS P
Sbjct: 714 AMN---CSNLWGNFSYGSICSFHCLEGQ------LLNGSAQTACQEN----GHWSTTVPT 760
Query: 682 C 682
C
Sbjct: 761 C 761
Score = 165 bits (417), Expect = 5e-40
Identities = 143/578 (24%), Positives = 219/578 (37%), Gaps = 57/578 (9%)
Query: 63 FPIGTYLNYECRPGYS-GRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNG---MVHVI 118
F + ++ C GY P + CL + +WT +C C P G +H
Sbjct: 220 FSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSA 279
Query: 119 KGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFI 178
K Q S +SC +G+ L+G C SG +W P+C + C + G
Sbjct: 280 KAFQHQSSCSFSCEEGFALVGPEVVQCTASG---VWTAPAPVCKAVQCQHLEAPSEGTMD 336
Query: 179 STN-RENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 237
+ F YGS + C PG + + G + C + G WS P P C +
Sbjct: 337 CVHPLTAFAYGSSCKFECQPG------YRVRGLDMLRCIDS----GHWSAPLPTCEAIS- 385
Query: 238 CTP--PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSR 295
C P V + S + F + FRC GF+++G V+C L +W P C
Sbjct: 386 CEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQA 445
Query: 296 V-CQPPPDVLHAE-RTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 353
+ CQ P A F ++C G L GA+ ++C G+W+ P C
Sbjct: 446 LQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPEC 505
Query: 354 EVKSCDDFMGQLLNGRVLFPVNL---QLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWN 410
+ C + NG + L + F+CDEG+ L G C +G W
Sbjct: 506 QAIPCTPLLSP-QNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGR---WT 561
Query: 411 SSVPVCEQIFCPSPPVIPNGR-HTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIR 469
S P+CE I CP G F G T +++CD F L G + +
Sbjct: 562 DSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCD------NGFKLEGPNNVE 615
Query: 470 CTSDPQGNGVWSSPAPRC-GILG------HCQAPDHFLFAKLKTQTNASDFPIGTSLKYE 522
CT+ +G WS+ P C GI C A + + + F T+ +
Sbjct: 616 CTT----SGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFG 671
Query: 523 CRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCK----TPPDPVNGMVHVITDIQVGSRI 577
C + +++C + W++ C+ C P +N ++ + GS
Sbjct: 672 CNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMN-CSNLWGNFSYGSIC 730
Query: 578 NYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIP 615
++ C G L G + C +G HWST P CQ P
Sbjct: 731 SFHCLEGQLLNGSAQTACQENG---HWSTTVPTCQAGP 765
Score = 156 bits (394), Expect = 2e-37
Identities = 151/638 (23%), Positives = 234/638 (36%), Gaps = 71/638 (11%)
Query: 456 RGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHC---QAPDHFLFAKLKTQTNASD 512
+G + IG T C G P C + C + P H L + +
Sbjct: 171 QGECLETIGNYTCSCYPGFYG--------PECEYVRECGELELPQHVL---MNCSHPLGN 219
Query: 513 FPIGTSLKYECRPEYY-GRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNG---MVHVI 568
F + + C Y P + CL + +W++ C C P G +H
Sbjct: 220 FSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSA 279
Query: 569 TDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDFI 628
Q S ++SC G L+G +C SG W+ P+C+ + C + G
Sbjct: 280 KAFQHQSSCSFSCEEGFALVGPEVVQCTASGV---WTAPAPVCKAVQCQHLEAPSEGTMD 336
Query: 629 STNREN-FHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 687
+ F YGS + C PG + + G + C + G WS P P C +
Sbjct: 337 CVHPLTAFAYGSSCKFECQPG------YRVRGLDMLRCIDS----GHWSAPLPTCEAIS- 385
Query: 688 CTPPN--VENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSR 745
C P V + S + F + FRC GF+++G V+C L +W P C
Sbjct: 386 CEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQA 445
Query: 746 V-CQPPPDVLHAE-RTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTC 803
+ CQ P A F ++C G L GA+ ++C G+W+ P C
Sbjct: 446 LQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPEC 505
Query: 804 EVKSCDDFMGQLLNGRVLFPVNL---QLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWN 860
+ C + NG + L + F+CDEG+ L G C +G W
Sbjct: 506 QAIPCTPLLSPQ-NGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGR---WT 561
Query: 861 SSVPVCEQIFCPSPPVIPNGR-HTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIR 919
S P+CE I CP G F G +++CD F L G + +
Sbjct: 562 DSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCD------NGFKLEGPNNVE 615
Query: 920 CTSDPQGNGVWSSPAPRC-GILG------HCQAPDHFLFAKLKTQTNASDFPIGTSLKYE 972
CT+ +G WS+ P C GI C A + + + F T+ +
Sbjct: 616 CTT----SGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFG 671
Query: 973 CRPEY-YGRPFSITCLDNLVWSSPKDVCKRKSCK----TPPDPVNGMVHVITDIQVGSRI 1027
C + +++C + W++ C+ C P +N ++ + GS
Sbjct: 672 CNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMN-CSNLWGNFSYGSIC 730
Query: 1028 NYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIP 1065
++ C G L G + C +G HWST P CQ P
Sbjct: 731 SFHCLEGQLLNGSAQTACQENG---HWSTTVPTCQAGP 765
Score = 95.1 bits (235), Expect = 6e-19
Identities = 82/337 (24%), Positives = 120/337 (35%), Gaps = 42/337 (12%)
Query: 43 CNAPEWLPFARPTNLTDEFEFPIGTY-----LNYECRPGYSGRPFSII-CLKNSVWTGAK 96
C A + P P G + ++ C G S++ CL W
Sbjct: 443 CQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVP 502
Query: 97 DRCRRKSCRNPPDPVNGMVHVIKGI---QFGSQIKYSCTKGYRLIGSSSATCIISGDTVI 153
C+ C P NG + ++ + + S ++ C +GY L G C SG
Sbjct: 503 PECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGR--- 559
Query: 154 WDNETPICDRIPCGLPPTITNGDF-ISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPS 212
W + P+C+ I C G S R F+ GS + C+ G F+L G +
Sbjct: 560 WTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNG------FKLEGPNN 613
Query: 213 IYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSL---------FSLNEVVE 263
+ CT++ G WS P C P V+ L + + F N
Sbjct: 614 VECTTS----GRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCY 669
Query: 264 FRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDK-----DNFS 317
F C GF + G + C+ +W P+C V C LH + NFS
Sbjct: 670 FGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSE----LHVNKPIAMNCSNLWGNFS 725
Query: 318 PGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCE 354
G + C G L G+A C G WS PTC+
Sbjct: 726 YGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQ 762
>gi|168693643 decay accelerating factor for complement isoform 2
precursor [Homo sapiens]
Length = 440
Score = 168 bits (426), Expect = 4e-41
Identities = 101/268 (37%), Positives = 139/268 (51%), Gaps = 26/268 (9%)
Query: 421 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLI-GES-TIRCTSDPQGNG 478
C PP +PN + + FP + Y C+ SF I GE ++ C Q
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEE------SFVKIPGEKDSVICLKGSQ--- 86
Query: 479 VWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASD-FPIGTSLKYECRPEYYGRPF---SI 534
WS C C+ P A LK + FP+GT ++YECRP Y P +
Sbjct: 87 -WSDIEEFCN--RSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKL 143
Query: 535 TCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAE 594
TCL NL WS+ + CK+KSC P + NG + V I G+ I++SC TG++L G +S+
Sbjct: 144 TCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSF 203
Query: 595 CILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKV 654
C++SG++ WS P C+ I C PP I NG I R+++ Y VTY CN G
Sbjct: 204 CLISGSSVQWSDPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG------ 256
Query: 655 FELVGEPSIYCTSNDDQVGIWSGPAPQC 682
F ++GE SIYCT N+D+ G WSGP P+C
Sbjct: 257 FTMIGEHSIYCTVNNDE-GEWSGPPPEC 283
Score = 168 bits (425), Expect = 6e-41
Identities = 101/268 (37%), Positives = 139/268 (51%), Gaps = 26/268 (9%)
Query: 871 CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLI-GES-TIRCTSDPQGNG 928
C PP +PN + + FP + Y C+ SF I GE ++ C Q
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEE------SFVKIPGEKDSVICLKGSQ--- 86
Query: 929 VWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASD-FPIGTSLKYECRPEYYGRPF---SI 984
WS C C+ P A LK + FP+GT ++YECRP Y P +
Sbjct: 87 -WSDIEEFCN--RSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKL 143
Query: 985 TCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAE 1044
TCL NL WS+ + CK+KSC P + NG + V I G+ I++SC TG++L G +S+
Sbjct: 144 TCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSF 203
Query: 1045 CILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKV 1104
C++SG++ WS P C+ I C PP I NG I R+++ Y VTY CN G
Sbjct: 204 CLISGSSVQWSDPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG------ 256
Query: 1105 FELVGEPSIYCTSNDDQVGIWSGPAPQC 1132
F ++GE SIYCT N+D+ G WSGP P+C
Sbjct: 257 FTMIGEHSIYCTVNNDE-GEWSGPPPEC 283
Score = 162 bits (410), Expect = 3e-39
Identities = 80/173 (46%), Positives = 106/173 (61%), Gaps = 11/173 (6%)
Query: 63 FPIGTYLNYECRPGYSGRPF---SIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIK 119
FP+GT + YECRPGY P + CL+N W+ A + C++KSC NP + NG + V
Sbjct: 119 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPG 178
Query: 120 GIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFIS 179
GI FG+ I +SC GY+L GS+S+ C+ISG +V W + P C I C PP I NG I
Sbjct: 179 GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNG-IIQ 237
Query: 180 TNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 232
R+++ Y VTY CN G F ++GE SIYCT N+D+ G WSGP P+C
Sbjct: 238 GERDHYGYRQSVTYACNKG------FTMIGEHSIYCTVNNDE-GEWSGPPPEC 283
Score = 155 bits (391), Expect = 5e-37
Identities = 95/270 (35%), Positives = 131/270 (48%), Gaps = 27/270 (10%)
Query: 1321 CPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGES-TIRCTSDPHGNGV 1379
C PP + N + P I+Y C+ + GE ++ C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEES-----FVKIPGEKDSVICLKGSQ---- 86
Query: 1380 WSSPAPRCELSVRAGHCKTPEQFPFASPTIP-INDFEFPVGTSLNYECRPGYFGKMF--- 1435
WS C S C+ P + AS P I FPVGT + YECRPGY +
Sbjct: 87 WSDIEEFCNRS-----CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSP 141
Query: 1436 SISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPS 1495
++CL+NL WS+ + C++KSC P E NG + + FG+T+++SCN G++L GS S
Sbjct: 142 KLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTS 201
Query: 1496 TTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGE 1555
+ CL+SG++V W P C I C PP I NG R + VTY C+ G
Sbjct: 202 SFCLISGSSVQWSDPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG---- 256
Query: 1556 QLFELVGERSIYCTSKDDQVGVWSSPPPRC 1585
F ++GE SIYCT +D+ G WS PPP C
Sbjct: 257 --FTMIGEHSIYCTVNNDE-GEWSGPPPEC 283
Score = 136 bits (342), Expect = 2e-31
Identities = 80/254 (31%), Positives = 131/254 (51%), Gaps = 15/254 (5%)
Query: 240 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFV-MKGPR-RVKCQALNKWEPELPSCSRVC 297
PP+V N + R+ F + V+ ++C+ FV + G + V C ++W C+R C
Sbjct: 39 PPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSC 98
Query: 298 QPPPDVLHAERTQR--DKDNFSPGQEVFYSCEPGYDLRGAAS--MRCTPQGDWSPAAPTC 353
+ P + A Q ++ F G V Y C PGY + S + C WS A C
Sbjct: 99 EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFC 158
Query: 354 EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSV 413
+ KSC + G++ NG++ P + GA + F C+ G++L GS++S+C+++G W+ +
Sbjct: 159 KKKSCPN-PGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPL 217
Query: 414 PVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSD 473
P C +I+CP+PP I NG G+ + + + ++V Y C+ F +IGE +I CT +
Sbjct: 218 PECREIYCPAPPQIDNGIIQGE-RDHYGYRQSVTYACN------KGFTMIGEHSIYCTVN 270
Query: 474 PQGNGVWSSPAPRC 487
G WS P P C
Sbjct: 271 -NDEGEWSGPPPEC 283
Score = 136 bits (342), Expect = 2e-31
Identities = 80/254 (31%), Positives = 131/254 (51%), Gaps = 15/254 (5%)
Query: 690 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFV-MKGPR-RVKCQALNKWEPELPSCSRVC 747
PP+V N + R+ F + V+ ++C+ FV + G + V C ++W C+R C
Sbjct: 39 PPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSC 98
Query: 748 QPPPDVLHAERTQR--DKDNFSPGQEVFYSCEPGYDLRGAAS--MRCTPQGDWSPAAPTC 803
+ P + A Q ++ F G V Y C PGY + S + C WS A C
Sbjct: 99 EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFC 158
Query: 804 EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSV 863
+ KSC + G++ NG++ P + GA + F C+ G++L GS++S+C+++G W+ +
Sbjct: 159 KKKSCPN-PGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPL 217
Query: 864 PVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSD 923
P C +I+CP+PP I NG G+ + + + ++V Y C+ F +IGE +I CT +
Sbjct: 218 PECREIYCPAPPQIDNGIIQGE-RDHYGYRQSVTYACN------KGFTMIGEHSIYCTVN 270
Query: 924 PQGNGVWSSPAPRC 937
G WS P P C
Sbjct: 271 -NDEGEWSGPPPEC 283
Score = 127 bits (320), Expect = 9e-29
Identities = 78/253 (30%), Positives = 120/253 (47%), Gaps = 15/253 (5%)
Query: 1594 PEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSH--TVQCQTNGRWGPKLPHCSRVCQ 1651
P+V NA R+ F +I ++C+ FV + +V C +W C+R C+
Sbjct: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCE 99
Query: 1652 PPPEILHGEHTLSH--QDNFSPGQEVFYSCEPSYDLRGAAS--LHCTPQGDWSPEAPRCT 1707
P + + Q+ F G V Y C P Y + S L C WS C
Sbjct: 100 VPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCK 159
Query: 1708 VKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVP 1767
KSC + G++ +G++ +P + GA +SF C+ G++L G ++S C+++G W+ +P
Sbjct: 160 KKSCPN-PGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLP 218
Query: 1768 VCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDP 1827
C +I+CP PP I NG G Y + ++YAC+ F +IGE SI CT +
Sbjct: 219 ECREIYCPAPPQIDNGIIQGER-DHYGYRQSVTYACN------KGFTMIGEHSIYCTVN- 270
Query: 1828 QGNGVWSSPAPRC 1840
G WS P P C
Sbjct: 271 NDEGEWSGPPPEC 283
Score = 125 bits (313), Expect = 6e-28
Identities = 79/254 (31%), Positives = 123/254 (48%), Gaps = 15/254 (5%)
Query: 1140 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFV-MKGPR-RVKCQALNKWEPELPSCSRVC 1197
PP+V N + R+ F + V+ ++C+ FV + G + V C ++W C+R C
Sbjct: 39 PPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSC 98
Query: 1198 QPPPEILHGEHTPSH--QDNFSPGQEVFYSCEPGYDLRGAAS--LHCTPQGDWSPEAPRC 1253
+ P + + Q+ F G V Y C PGY + S L C WS C
Sbjct: 99 EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFC 158
Query: 1254 AVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSV 1313
KSC + G++ +G++ P + GA +SF C+ G++L GS+ S C++ G W++ +
Sbjct: 159 KKKSCPN-PGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPL 217
Query: 1314 PVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSD 1373
P C I+CP PP I NG G Y + ++Y C+ F +IGE +I CT +
Sbjct: 218 PECREIYCPAPPQIDNGIIQG-ERDHYGYRQSVTYACN------KGFTMIGEHSIYCTVN 270
Query: 1374 PHGNGVWSSPAPRC 1387
+ G WS P P C
Sbjct: 271 -NDEGEWSGPPPEC 283
Score = 115 bits (288), Expect = 4e-25
Identities = 84/291 (28%), Positives = 125/291 (42%), Gaps = 30/291 (10%)
Query: 28 LAVVVLLALPVAWGQCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGY---SGRPFSI 84
L ++VLL LP WG C P +P A+P L FP T + Y+C + G S+
Sbjct: 21 LLLLVLLCLPAVWGDCGLPPDVPNAQPA-LEGRTSFPEDTVITYKCEESFVKIPGEKDSV 79
Query: 85 ICLKNSVWTGAKDRCRRKSCRNPPDPVNGMV---HVIKG-IQFGSQIKYSCTKGYRLIGS 140
ICLK S W+ ++ C R SC P + + ++ + G+ ++Y C GYR S
Sbjct: 80 ICLKGSQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPS 138
Query: 141 SS--ATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPG 198
S TC+ + W C + C P I NG +G+ +++ CN G
Sbjct: 139 LSPKLTCL---QNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPG--GILFGATISFSCNTG 193
Query: 199 SGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSL 258
++L G S +C + V WS P P+C PP ++NGI + R +
Sbjct: 194 ------YKLFGSTSSFCLISGSSVQ-WSDPLPECREIYCPAPPQIDNGI-IQGERDHYGY 245
Query: 259 NEVVEFRCQPGFVMKGPRRVKCQALN---KWEPELPSC---SRVCQPPPDV 303
+ V + C GF M G + C N +W P C S + PP V
Sbjct: 246 RQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
Score = 114 bits (284), Expect = 1e-24
Identities = 80/278 (28%), Positives = 115/278 (41%), Gaps = 30/278 (10%)
Query: 1394 GHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYF---GKMFSISCLENLVWSSVED 1450
G C P P A P + FP T + Y+C + G+ S+ CL+ WS +E+
Sbjct: 34 GDCGLPPDVPNAQPALE-GRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEE 92
Query: 1451 NCRRKSCGPPPEPFNGMVHINTDTQ----FGSTVNYSCNEGFRLIGS--PSTTCLVSGNN 1504
C R SC P + + TQ G+ V Y C G+R S P TCL N
Sbjct: 93 FCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCL---QN 148
Query: 1505 VTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGER 1564
+ W C+ SC P I NG F G +++ C+TG ++L G
Sbjct: 149 LKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF--GATISFSCNTG------YKLFGST 200
Query: 1565 SIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFV 1624
S +C V WS P P C P+++N I + G R + + + + C GF
Sbjct: 201 SSFCLISGSSVQ-WSDPLPECREIYCPAPPQIDNGI-IQGERDHYGYRQSVTYACNKGFT 258
Query: 1625 MVGSHTVQCQTN---GRWGPKLPHC---SRVCQPPPEI 1656
M+G H++ C N G W P C S + PP +
Sbjct: 259 MIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
Score = 94.0 bits (232), Expect = 1e-18
Identities = 78/266 (29%), Positives = 122/266 (45%), Gaps = 27/266 (10%)
Query: 1650 CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSY-DLRGAA-SLHCTPQGDWSPEAPRCT 1707
C PP++ + + L + +F + Y CE S+ + G S+ C WS C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 1708 VKSCDDFLGQLPHGRVLLPLNLQ----LGAKVSFVCDEGFRLKGRSASHCVLAGMKALWN 1763
+SC + +L + P Q +G V + C G+R + S S + W+
Sbjct: 96 -RSC-EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYR-REPSLSPKLTCLQNLKWS 152
Query: 1764 SSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRC 1823
++V C++ CPNP I NG+ P G I +G IS++C+T + L G +S C
Sbjct: 153 TAVEFCKKKSCPNPGEIRNGQ-IDVP-GGILFGATISFSCNT------GYKLFGSTSSFC 204
Query: 1824 TSDPQGNGV-WSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYL 1882
G+ V WS P P C CP PP+I NG I G Y +++Y C+ G+
Sbjct: 205 LI--SGSSVQWSDPLPECR---EIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKGFT 258
Query: 1883 LVGKGFIFCT---DQGIWSQLDHYCK 1905
++G+ I+CT D+G WS C+
Sbjct: 259 MIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 90.1 bits (222), Expect = 2e-17
Identities = 75/278 (26%), Positives = 113/278 (40%), Gaps = 26/278 (9%)
Query: 489 ILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY---GRPFSITCLDNLVWSSP 545
+ G C P A+ + S FP T + Y+C + G S+ CL WS
Sbjct: 32 VWGDCGLPPDVPNAQPALEGRTS-FPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDI 90
Query: 546 KDVCKRKSCKTPPDPVNGMVH--VITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNA 601
++ C R SC+ P + + IT VG+ + Y C G+R S + N
Sbjct: 91 EEFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNL 149
Query: 602 AHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEP 661
WST C++ C P I NG +G+ +++ CN G ++L G
Sbjct: 150 K-WSTAVEFCKKKSCPNPGEIRNGQIDVPG--GILFGATISFSCNTG------YKLFGST 200
Query: 662 SIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFV 721
S +C + V WS P P+C PP ++NGI+ + R + + V + C GF
Sbjct: 201 SSFCLISGSSVQ-WSDPLPECREIYCPAPPQIDNGIIQGE-RDHYGYRQSVTYACNKGFT 258
Query: 722 MKGPRRVKCQALN---KWEPELPSC---SRVCQPPPDV 753
M G + C N +W P C S + PP V
Sbjct: 259 MIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
Score = 89.7 bits (221), Expect = 3e-17
Identities = 74/278 (26%), Positives = 113/278 (40%), Gaps = 26/278 (9%)
Query: 939 ILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY---GRPFSITCLDNLVWSSP 995
+ G C P A+ + S FP T + Y+C + G S+ CL WS
Sbjct: 32 VWGDCGLPPDVPNAQPALEGRTS-FPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDI 90
Query: 996 KDVCKRKSCKTPPDPVNGMVH--VITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNT 1051
++ C R SC+ P + + IT VG+ + Y C G+R S + N
Sbjct: 91 EEFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNL 149
Query: 1052 AHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEP 1111
WST C++ C P I NG +G+ +++ CN G ++L G
Sbjct: 150 K-WSTAVEFCKKKSCPNPGEIRNGQIDVPG--GILFGATISFSCNTG------YKLFGST 200
Query: 1112 SIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFV 1171
S +C + V WS P P+C PP ++NGI+ + R + + V + C GF
Sbjct: 201 SSFCLISGSSVQ-WSDPLPECREIYCPAPPQIDNGIIQGE-RDHYGYRQSVTYACNKGFT 258
Query: 1172 MKGPRRVKCQALN---KWEPELPSC---SRVCQPPPEI 1203
M G + C N +W P C S + PP +
Sbjct: 259 MIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
Score = 83.6 bits (205), Expect = 2e-15
Identities = 74/267 (27%), Positives = 109/267 (40%), Gaps = 28/267 (10%)
Query: 1457 CGPPPEPFNGMVHINTDTQF--GSTVNYSCNEGF-RLIGSPSTTCLVSGNNVTWDKKAPI 1513
CG PP+ N + T F + + Y C E F ++ G + + G+ W
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQ--WSDIEEF 93
Query: 1514 CEIISCEPPPTISNGDFYSNNRTS--FHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSK 1571
C SCE P +++ T F GTVV Y+C G E + C
Sbjct: 94 CNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLS----PKLTCL-- 146
Query: 1572 DDQVGVWSSPPPRCISTNKCTAPEVENA-IRVPGNRSFFTLTEIIRFRCQPGFVMVGSHT 1630
Q WS+ C + E+ N I VPG F I F C G+ + GS +
Sbjct: 147 --QNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGAT---ISFSCNTGYKLFGSTS 201
Query: 1631 VQCQTNG---RWGPKLPHCSRV-CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLR 1686
C +G +W LP C + C PP+I +G +D++ Q V Y+C + +
Sbjct: 202 SFCLISGSSVQWSDPLPECREIYCPAPPQIDNGI-IQGERDHYGYRQSVTYACNKGFTMI 260
Query: 1687 GAASLHCT---PQGDWSPEAPRCTVKS 1710
G S++CT +G+WS P C KS
Sbjct: 261 GEHSIYCTVNNDEGEWSGPPPECRGKS 287
Score = 67.8 bits (164), Expect = 1e-10
Identities = 78/288 (27%), Positives = 121/288 (42%), Gaps = 41/288 (14%)
Query: 290 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY-DLRGAA-SMRCTPQGDWS 347
LP+ C PPDV +A+ + +F + Y CE + + G S+ C WS
Sbjct: 29 LPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS 88
Query: 348 PAAPTCEVKSCDDFMGQLLNGRVL---------FPVNLQLGAKVDFVCDEGFQLKGS-SA 397
C +SC+ + LN L FPV G V++ C G++ + S S
Sbjct: 89 DIEEFCN-RSCE--VPTRLNSASLKQPYITQNYFPV----GTVVEYECRPGYRREPSLSP 141
Query: 398 SYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRG 457
L ++ W+++V C++ CP+P I NG+ P + FG T++++C+
Sbjct: 142 KLTCLQNLK--WSTAVEFCKKKSCPNPGEIRNGQ-IDVPGGIL-FGATISFSCN------ 191
Query: 458 TSFDLIGESTIRCTSDPQGNGV-WSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIG 516
T + L G ++ C G+ V WS P P C + +C AP + Q +
Sbjct: 192 TGYKLFGSTSSFCLI--SGSSVQWSDPLPECREI-YCPAPPQIDNGII--QGERDHYGYR 246
Query: 517 TSLKYECRPEY-YGRPFSITCL---DNLVWSSPKDVCKRKS--CKTPP 558
S+ Y C + SI C D WS P C+ KS K PP
Sbjct: 247 QSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPP 294
Score = 65.9 bits (159), Expect = 4e-10
Identities = 77/288 (26%), Positives = 120/288 (41%), Gaps = 41/288 (14%)
Query: 740 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY-DLRGAA-SMRCTPQGDWS 797
LP+ C PPDV +A+ + +F + Y CE + + G S+ C WS
Sbjct: 29 LPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS 88
Query: 798 PAAPTCEVKSCDDFMGQLLNGRVL---------FPVNLQLGAKVDFVCDEGFQLKGS-SA 847
C +SC+ + LN L FPV G V++ C G++ + S S
Sbjct: 89 DIEEFCN-RSCE--VPTRLNSASLKQPYITQNYFPV----GTVVEYECRPGYRREPSLSP 141
Query: 848 SYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRG 907
L ++ W+++V C++ CP+P I NG+ P + FG ++++C+
Sbjct: 142 KLTCLQNLK--WSTAVEFCKKKSCPNPGEIRNGQ-IDVPGGIL-FGATISFSCN------ 191
Query: 908 TSFDLIGESTIRCTSDPQGNGV-WSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIG 966
T + L G ++ C G+ V WS P P C + +C AP + Q +
Sbjct: 192 TGYKLFGSTSSFCLI--SGSSVQWSDPLPECREI-YCPAPPQIDNGII--QGERDHYGYR 246
Query: 967 TSLKYECRPEY-YGRPFSITCL---DNLVWSSPKDVCKRKS--CKTPP 1008
S+ Y C + SI C D WS P C+ KS K PP
Sbjct: 247 QSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPP 294
Score = 65.5 bits (158), Expect = 5e-10
Identities = 67/269 (24%), Positives = 101/269 (37%), Gaps = 33/269 (12%)
Query: 366 LNGRVLFPVNLQLGAKVDFVCDEGF-QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSP 424
L GR FP + + + C+E F ++ G S L G S W+ C + C P
Sbjct: 49 LEGRTSFPED----TVITYKCEESFVKIPGEKDSVICLKG--SQWSDIEEFCNRS-CEVP 101
Query: 425 PVIPNGRHTGKPL---EVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 481
+ N +P FP G V Y C P R S + C N WS
Sbjct: 102 TRL-NSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLS----PKLTCLQ----NLKWS 152
Query: 482 SPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD- 538
+ C C P ++ G ++ + C Y +G S +
Sbjct: 153 TAVEFCKKKS-CPNPGEIRNGQIDVP---GGILFGATISFSCNTGYKLFGSTSSFCLISG 208
Query: 539 -NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSR--INYSCTTGHRLIGHSSAEC 595
++ WS P C+ C PP NG++ D G R + Y+C G +IG S C
Sbjct: 209 SSVQWSDPLPECREIYCPAPPQIDNGIIQGERD-HYGYRQSVTYACNKGFTMIGEHSIYC 267
Query: 596 ILSGNAAHWSTKPPIC--QRIPCGLPPTI 622
++ + WS PP C + + +PPT+
Sbjct: 268 TVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
Score = 65.5 bits (158), Expect = 5e-10
Identities = 67/269 (24%), Positives = 101/269 (37%), Gaps = 33/269 (12%)
Query: 816 LNGRVLFPVNLQLGAKVDFVCDEGF-QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSP 874
L GR FP + + + C+E F ++ G S L G S W+ C + C P
Sbjct: 49 LEGRTSFPED----TVITYKCEESFVKIPGEKDSVICLKG--SQWSDIEEFCNRS-CEVP 101
Query: 875 PVIPNGRHTGKPL---EVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 931
+ N +P FP G V Y C P R S + C N WS
Sbjct: 102 TRL-NSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLS----PKLTCLQ----NLKWS 152
Query: 932 SPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD- 988
+ C C P ++ G ++ + C Y +G S +
Sbjct: 153 TAVEFCKKKS-CPNPGEIRNGQIDVP---GGILFGATISFSCNTGYKLFGSTSSFCLISG 208
Query: 989 -NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSR--INYSCTTGHRLIGHSSAEC 1045
++ WS P C+ C PP NG++ D G R + Y+C G +IG S C
Sbjct: 209 SSVQWSDPLPECREIYCPAPPQIDNGIIQGERD-HYGYRQSVTYACNKGFTMIGEHSIYC 267
Query: 1046 ILSGNTAHWSTKPPIC--QRIPCGLPPTI 1072
++ + WS PP C + + +PPT+
Sbjct: 268 TVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
Score = 62.4 bits (150), Expect = 4e-09
Identities = 64/247 (25%), Positives = 100/247 (40%), Gaps = 32/247 (12%)
Query: 1735 VSFVCDEGF-RLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPF--- 1790
+++ C+E F ++ G S L G + W+ C + P LN P+
Sbjct: 61 ITYKCEESFVKIPGEKDSVICLKGSQ--WSDIEEFCNRSC--EVPTRLNSASLKQPYITQ 116
Query: 1791 GDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPH 1850
P G + Y C R + + + C N WS+ C+ +CP+
Sbjct: 117 NYFPVGTVVEYECRPGYRREPSLS----PKLTCLQ----NLKWSTAVEFCKKK---SCPN 165
Query: 1851 PPKIQNGHY-IGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGI---WSQLDHYCKE 1906
P +I+NG + G + L G TIS+ C+ GY L G FC G WS C+E
Sbjct: 166 PGEIRNGQIDVPGGI---LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECRE 222
Query: 1907 VNC-SFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADD---RWDPPL 1962
+ C + P NGI + + Y Y VT C G+T+ G C ++ W P
Sbjct: 223 IYCPAPPQIDNGIIQ--GERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPP 280
Query: 1963 AKCTSRT 1969
+C ++
Sbjct: 281 PECRGKS 287
Score = 61.6 bits (148), Expect = 7e-09
Identities = 74/279 (26%), Positives = 113/279 (40%), Gaps = 32/279 (11%)
Query: 1190 LPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGY-DLRGAA-SLHCTPQGDWS 1247
LP+ C PP++ + + + +F + Y CE + + G S+ C WS
Sbjct: 29 LPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS 88
Query: 1248 PEAPRCAVKSCDDFLGQLPHGRVLFPLNLQ----LGAKVSFVCDEGFRLKGSSVSHCVLV 1303
C +SC + +L + P Q +G V + C G+R + S+S +
Sbjct: 89 DIEEFCN-RSC-EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYR-REPSLSPKLTC 145
Query: 1304 GMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLI 1363
W+ +V C+ CPNP I NG+ P G I +G IS++C+ + L
Sbjct: 146 LQNLKWSTAVEFCKKKSCPNPGEIRNGQ-IDVPGG-ILFGATISFSCN------TGYKLF 197
Query: 1364 GESTIRCTSDPHGNGV-WSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSL 1422
G ++ C G+ V WS P P C R +C P Q + I + S+
Sbjct: 198 GSTSSFCLIS--GSSVQWSDPLPEC----REIYCPAPPQID--NGIIQGERDHYGYRQSV 249
Query: 1423 NYECRPGY--FGKMFSISCLENL---VWSSVEDNCRRKS 1456
Y C G+ G+ SI C N WS CR KS
Sbjct: 250 TYACNKGFTMIGE-HSIYCTVNNDEGEWSGPPPECRGKS 287
>gi|10835143 decay accelerating factor for complement isoform 1
preproprotein [Homo sapiens]
Length = 381
Score = 168 bits (426), Expect = 4e-41
Identities = 101/268 (37%), Positives = 139/268 (51%), Gaps = 26/268 (9%)
Query: 421 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLI-GES-TIRCTSDPQGNG 478
C PP +PN + + FP + Y C+ SF I GE ++ C Q
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEE------SFVKIPGEKDSVICLKGSQ--- 86
Query: 479 VWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASD-FPIGTSLKYECRPEYYGRPF---SI 534
WS C C+ P A LK + FP+GT ++YECRP Y P +
Sbjct: 87 -WSDIEEFCN--RSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKL 143
Query: 535 TCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAE 594
TCL NL WS+ + CK+KSC P + NG + V I G+ I++SC TG++L G +S+
Sbjct: 144 TCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSF 203
Query: 595 CILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKV 654
C++SG++ WS P C+ I C PP I NG I R+++ Y VTY CN G
Sbjct: 204 CLISGSSVQWSDPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG------ 256
Query: 655 FELVGEPSIYCTSNDDQVGIWSGPAPQC 682
F ++GE SIYCT N+D+ G WSGP P+C
Sbjct: 257 FTMIGEHSIYCTVNNDE-GEWSGPPPEC 283
Score = 168 bits (425), Expect = 6e-41
Identities = 101/268 (37%), Positives = 139/268 (51%), Gaps = 26/268 (9%)
Query: 871 CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLI-GES-TIRCTSDPQGNG 928
C PP +PN + + FP + Y C+ SF I GE ++ C Q
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEE------SFVKIPGEKDSVICLKGSQ--- 86
Query: 929 VWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASD-FPIGTSLKYECRPEYYGRPF---SI 984
WS C C+ P A LK + FP+GT ++YECRP Y P +
Sbjct: 87 -WSDIEEFCN--RSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKL 143
Query: 985 TCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAE 1044
TCL NL WS+ + CK+KSC P + NG + V I G+ I++SC TG++L G +S+
Sbjct: 144 TCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSF 203
Query: 1045 CILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKV 1104
C++SG++ WS P C+ I C PP I NG I R+++ Y VTY CN G
Sbjct: 204 CLISGSSVQWSDPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG------ 256
Query: 1105 FELVGEPSIYCTSNDDQVGIWSGPAPQC 1132
F ++GE SIYCT N+D+ G WSGP P+C
Sbjct: 257 FTMIGEHSIYCTVNNDE-GEWSGPPPEC 283
Score = 162 bits (410), Expect = 3e-39
Identities = 80/173 (46%), Positives = 106/173 (61%), Gaps = 11/173 (6%)
Query: 63 FPIGTYLNYECRPGYSGRPF---SIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIK 119
FP+GT + YECRPGY P + CL+N W+ A + C++KSC NP + NG + V
Sbjct: 119 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPG 178
Query: 120 GIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFIS 179
GI FG+ I +SC GY+L GS+S+ C+ISG +V W + P C I C PP I NG I
Sbjct: 179 GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNG-IIQ 237
Query: 180 TNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 232
R+++ Y VTY CN G F ++GE SIYCT N+D+ G WSGP P+C
Sbjct: 238 GERDHYGYRQSVTYACNKG------FTMIGEHSIYCTVNNDE-GEWSGPPPEC 283
Score = 155 bits (391), Expect = 5e-37
Identities = 95/270 (35%), Positives = 131/270 (48%), Gaps = 27/270 (10%)
Query: 1321 CPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGES-TIRCTSDPHGNGV 1379
C PP + N + P I+Y C+ + GE ++ C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEES-----FVKIPGEKDSVICLKGSQ---- 86
Query: 1380 WSSPAPRCELSVRAGHCKTPEQFPFASPTIP-INDFEFPVGTSLNYECRPGYFGKMF--- 1435
WS C S C+ P + AS P I FPVGT + YECRPGY +
Sbjct: 87 WSDIEEFCNRS-----CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSP 141
Query: 1436 SISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPS 1495
++CL+NL WS+ + C++KSC P E NG + + FG+T+++SCN G++L GS S
Sbjct: 142 KLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTS 201
Query: 1496 TTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGE 1555
+ CL+SG++V W P C I C PP I NG R + VTY C+ G
Sbjct: 202 SFCLISGSSVQWSDPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG---- 256
Query: 1556 QLFELVGERSIYCTSKDDQVGVWSSPPPRC 1585
F ++GE SIYCT +D+ G WS PPP C
Sbjct: 257 --FTMIGEHSIYCTVNNDE-GEWSGPPPEC 283
Score = 136 bits (342), Expect = 2e-31
Identities = 80/254 (31%), Positives = 131/254 (51%), Gaps = 15/254 (5%)
Query: 240 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFV-MKGPR-RVKCQALNKWEPELPSCSRVC 297
PP+V N + R+ F + V+ ++C+ FV + G + V C ++W C+R C
Sbjct: 39 PPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSC 98
Query: 298 QPPPDVLHAERTQR--DKDNFSPGQEVFYSCEPGYDLRGAAS--MRCTPQGDWSPAAPTC 353
+ P + A Q ++ F G V Y C PGY + S + C WS A C
Sbjct: 99 EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFC 158
Query: 354 EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSV 413
+ KSC + G++ NG++ P + GA + F C+ G++L GS++S+C+++G W+ +
Sbjct: 159 KKKSCPN-PGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPL 217
Query: 414 PVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSD 473
P C +I+CP+PP I NG G+ + + + ++V Y C+ F +IGE +I CT +
Sbjct: 218 PECREIYCPAPPQIDNGIIQGE-RDHYGYRQSVTYACN------KGFTMIGEHSIYCTVN 270
Query: 474 PQGNGVWSSPAPRC 487
G WS P P C
Sbjct: 271 -NDEGEWSGPPPEC 283
Score = 136 bits (342), Expect = 2e-31
Identities = 80/254 (31%), Positives = 131/254 (51%), Gaps = 15/254 (5%)
Query: 690 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFV-MKGPR-RVKCQALNKWEPELPSCSRVC 747
PP+V N + R+ F + V+ ++C+ FV + G + V C ++W C+R C
Sbjct: 39 PPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSC 98
Query: 748 QPPPDVLHAERTQR--DKDNFSPGQEVFYSCEPGYDLRGAAS--MRCTPQGDWSPAAPTC 803
+ P + A Q ++ F G V Y C PGY + S + C WS A C
Sbjct: 99 EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFC 158
Query: 804 EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSV 863
+ KSC + G++ NG++ P + GA + F C+ G++L GS++S+C+++G W+ +
Sbjct: 159 KKKSCPN-PGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPL 217
Query: 864 PVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSD 923
P C +I+CP+PP I NG G+ + + + ++V Y C+ F +IGE +I CT +
Sbjct: 218 PECREIYCPAPPQIDNGIIQGE-RDHYGYRQSVTYACN------KGFTMIGEHSIYCTVN 270
Query: 924 PQGNGVWSSPAPRC 937
G WS P P C
Sbjct: 271 -NDEGEWSGPPPEC 283
Score = 127 bits (320), Expect = 9e-29
Identities = 78/253 (30%), Positives = 120/253 (47%), Gaps = 15/253 (5%)
Query: 1594 PEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSH--TVQCQTNGRWGPKLPHCSRVCQ 1651
P+V NA R+ F +I ++C+ FV + +V C +W C+R C+
Sbjct: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCE 99
Query: 1652 PPPEILHGEHTLSH--QDNFSPGQEVFYSCEPSYDLRGAAS--LHCTPQGDWSPEAPRCT 1707
P + + Q+ F G V Y C P Y + S L C WS C
Sbjct: 100 VPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCK 159
Query: 1708 VKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVP 1767
KSC + G++ +G++ +P + GA +SF C+ G++L G ++S C+++G W+ +P
Sbjct: 160 KKSCPN-PGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLP 218
Query: 1768 VCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDP 1827
C +I+CP PP I NG G Y + ++YAC+ F +IGE SI CT +
Sbjct: 219 ECREIYCPAPPQIDNGIIQGER-DHYGYRQSVTYACN------KGFTMIGEHSIYCTVN- 270
Query: 1828 QGNGVWSSPAPRC 1840
G WS P P C
Sbjct: 271 NDEGEWSGPPPEC 283
Score = 125 bits (313), Expect = 6e-28
Identities = 79/254 (31%), Positives = 123/254 (48%), Gaps = 15/254 (5%)
Query: 1140 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFV-MKGPR-RVKCQALNKWEPELPSCSRVC 1197
PP+V N + R+ F + V+ ++C+ FV + G + V C ++W C+R C
Sbjct: 39 PPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSC 98
Query: 1198 QPPPEILHGEHTPSH--QDNFSPGQEVFYSCEPGYDLRGAAS--LHCTPQGDWSPEAPRC 1253
+ P + + Q+ F G V Y C PGY + S L C WS C
Sbjct: 99 EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFC 158
Query: 1254 AVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSV 1313
KSC + G++ +G++ P + GA +SF C+ G++L GS+ S C++ G W++ +
Sbjct: 159 KKKSCPN-PGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPL 217
Query: 1314 PVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSD 1373
P C I+CP PP I NG G Y + ++Y C+ F +IGE +I CT +
Sbjct: 218 PECREIYCPAPPQIDNGIIQG-ERDHYGYRQSVTYACN------KGFTMIGEHSIYCTVN 270
Query: 1374 PHGNGVWSSPAPRC 1387
+ G WS P P C
Sbjct: 271 -NDEGEWSGPPPEC 283
Score = 115 bits (288), Expect = 4e-25
Identities = 84/291 (28%), Positives = 125/291 (42%), Gaps = 30/291 (10%)
Query: 28 LAVVVLLALPVAWGQCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGY---SGRPFSI 84
L ++VLL LP WG C P +P A+P L FP T + Y+C + G S+
Sbjct: 21 LLLLVLLCLPAVWGDCGLPPDVPNAQPA-LEGRTSFPEDTVITYKCEESFVKIPGEKDSV 79
Query: 85 ICLKNSVWTGAKDRCRRKSCRNPPDPVNGMV---HVIKG-IQFGSQIKYSCTKGYRLIGS 140
ICLK S W+ ++ C R SC P + + ++ + G+ ++Y C GYR S
Sbjct: 80 ICLKGSQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPS 138
Query: 141 SS--ATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPG 198
S TC+ + W C + C P I NG +G+ +++ CN G
Sbjct: 139 LSPKLTCL---QNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPG--GILFGATISFSCNTG 193
Query: 199 SGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSL 258
++L G S +C + V WS P P+C PP ++NGI + R +
Sbjct: 194 ------YKLFGSTSSFCLISGSSVQ-WSDPLPECREIYCPAPPQIDNGI-IQGERDHYGY 245
Query: 259 NEVVEFRCQPGFVMKGPRRVKCQALN---KWEPELPSC---SRVCQPPPDV 303
+ V + C GF M G + C N +W P C S + PP V
Sbjct: 246 RQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
Score = 114 bits (284), Expect = 1e-24
Identities = 80/278 (28%), Positives = 115/278 (41%), Gaps = 30/278 (10%)
Query: 1394 GHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYF---GKMFSISCLENLVWSSVED 1450
G C P P A P + FP T + Y+C + G+ S+ CL+ WS +E+
Sbjct: 34 GDCGLPPDVPNAQPALE-GRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEE 92
Query: 1451 NCRRKSCGPPPEPFNGMVHINTDTQ----FGSTVNYSCNEGFRLIGS--PSTTCLVSGNN 1504
C R SC P + + TQ G+ V Y C G+R S P TCL N
Sbjct: 93 FCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCL---QN 148
Query: 1505 VTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGER 1564
+ W C+ SC P I NG F G +++ C+TG ++L G
Sbjct: 149 LKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF--GATISFSCNTG------YKLFGST 200
Query: 1565 SIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFV 1624
S +C V WS P P C P+++N I + G R + + + + C GF
Sbjct: 201 SSFCLISGSSVQ-WSDPLPECREIYCPAPPQIDNGI-IQGERDHYGYRQSVTYACNKGFT 258
Query: 1625 MVGSHTVQCQTN---GRWGPKLPHC---SRVCQPPPEI 1656
M+G H++ C N G W P C S + PP +
Sbjct: 259 MIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
Score = 94.0 bits (232), Expect = 1e-18
Identities = 78/266 (29%), Positives = 122/266 (45%), Gaps = 27/266 (10%)
Query: 1650 CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSY-DLRGAA-SLHCTPQGDWSPEAPRCT 1707
C PP++ + + L + +F + Y CE S+ + G S+ C WS C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 1708 VKSCDDFLGQLPHGRVLLPLNLQ----LGAKVSFVCDEGFRLKGRSASHCVLAGMKALWN 1763
+SC + +L + P Q +G V + C G+R + S S + W+
Sbjct: 96 -RSC-EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYR-REPSLSPKLTCLQNLKWS 152
Query: 1764 SSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRC 1823
++V C++ CPNP I NG+ P G I +G IS++C+T + L G +S C
Sbjct: 153 TAVEFCKKKSCPNPGEIRNGQ-IDVP-GGILFGATISFSCNT------GYKLFGSTSSFC 204
Query: 1824 TSDPQGNGV-WSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYL 1882
G+ V WS P P C CP PP+I NG I G Y +++Y C+ G+
Sbjct: 205 LI--SGSSVQWSDPLPECR---EIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKGFT 258
Query: 1883 LVGKGFIFCT---DQGIWSQLDHYCK 1905
++G+ I+CT D+G WS C+
Sbjct: 259 MIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 90.1 bits (222), Expect = 2e-17
Identities = 75/278 (26%), Positives = 113/278 (40%), Gaps = 26/278 (9%)
Query: 489 ILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY---GRPFSITCLDNLVWSSP 545
+ G C P A+ + S FP T + Y+C + G S+ CL WS
Sbjct: 32 VWGDCGLPPDVPNAQPALEGRTS-FPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDI 90
Query: 546 KDVCKRKSCKTPPDPVNGMVH--VITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNA 601
++ C R SC+ P + + IT VG+ + Y C G+R S + N
Sbjct: 91 EEFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNL 149
Query: 602 AHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEP 661
WST C++ C P I NG +G+ +++ CN G ++L G
Sbjct: 150 K-WSTAVEFCKKKSCPNPGEIRNGQIDVPG--GILFGATISFSCNTG------YKLFGST 200
Query: 662 SIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFV 721
S +C + V WS P P+C PP ++NGI+ + R + + V + C GF
Sbjct: 201 SSFCLISGSSVQ-WSDPLPECREIYCPAPPQIDNGIIQGE-RDHYGYRQSVTYACNKGFT 258
Query: 722 MKGPRRVKCQALN---KWEPELPSC---SRVCQPPPDV 753
M G + C N +W P C S + PP V
Sbjct: 259 MIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
Score = 89.7 bits (221), Expect = 3e-17
Identities = 74/278 (26%), Positives = 113/278 (40%), Gaps = 26/278 (9%)
Query: 939 ILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY---GRPFSITCLDNLVWSSP 995
+ G C P A+ + S FP T + Y+C + G S+ CL WS
Sbjct: 32 VWGDCGLPPDVPNAQPALEGRTS-FPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDI 90
Query: 996 KDVCKRKSCKTPPDPVNGMVH--VITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNT 1051
++ C R SC+ P + + IT VG+ + Y C G+R S + N
Sbjct: 91 EEFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNL 149
Query: 1052 AHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEP 1111
WST C++ C P I NG +G+ +++ CN G ++L G
Sbjct: 150 K-WSTAVEFCKKKSCPNPGEIRNGQIDVPG--GILFGATISFSCNTG------YKLFGST 200
Query: 1112 SIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFV 1171
S +C + V WS P P+C PP ++NGI+ + R + + V + C GF
Sbjct: 201 SSFCLISGSSVQ-WSDPLPECREIYCPAPPQIDNGIIQGE-RDHYGYRQSVTYACNKGFT 258
Query: 1172 MKGPRRVKCQALN---KWEPELPSC---SRVCQPPPEI 1203
M G + C N +W P C S + PP +
Sbjct: 259 MIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
Score = 83.6 bits (205), Expect = 2e-15
Identities = 74/267 (27%), Positives = 109/267 (40%), Gaps = 28/267 (10%)
Query: 1457 CGPPPEPFNGMVHINTDTQF--GSTVNYSCNEGF-RLIGSPSTTCLVSGNNVTWDKKAPI 1513
CG PP+ N + T F + + Y C E F ++ G + + G+ W
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQ--WSDIEEF 93
Query: 1514 CEIISCEPPPTISNGDFYSNNRTS--FHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSK 1571
C SCE P +++ T F GTVV Y+C G E + C
Sbjct: 94 CNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLS----PKLTCL-- 146
Query: 1572 DDQVGVWSSPPPRCISTNKCTAPEVENA-IRVPGNRSFFTLTEIIRFRCQPGFVMVGSHT 1630
Q WS+ C + E+ N I VPG F I F C G+ + GS +
Sbjct: 147 --QNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGAT---ISFSCNTGYKLFGSTS 201
Query: 1631 VQCQTNG---RWGPKLPHCSRV-CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLR 1686
C +G +W LP C + C PP+I +G +D++ Q V Y+C + +
Sbjct: 202 SFCLISGSSVQWSDPLPECREIYCPAPPQIDNGI-IQGERDHYGYRQSVTYACNKGFTMI 260
Query: 1687 GAASLHCT---PQGDWSPEAPRCTVKS 1710
G S++CT +G+WS P C KS
Sbjct: 261 GEHSIYCTVNNDEGEWSGPPPECRGKS 287
Score = 67.8 bits (164), Expect = 1e-10
Identities = 78/288 (27%), Positives = 121/288 (42%), Gaps = 41/288 (14%)
Query: 290 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY-DLRGAA-SMRCTPQGDWS 347
LP+ C PPDV +A+ + +F + Y CE + + G S+ C WS
Sbjct: 29 LPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS 88
Query: 348 PAAPTCEVKSCDDFMGQLLNGRVL---------FPVNLQLGAKVDFVCDEGFQLKGS-SA 397
C +SC+ + LN L FPV G V++ C G++ + S S
Sbjct: 89 DIEEFCN-RSCE--VPTRLNSASLKQPYITQNYFPV----GTVVEYECRPGYRREPSLSP 141
Query: 398 SYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRG 457
L ++ W+++V C++ CP+P I NG+ P + FG T++++C+
Sbjct: 142 KLTCLQNLK--WSTAVEFCKKKSCPNPGEIRNGQ-IDVPGGIL-FGATISFSCN------ 191
Query: 458 TSFDLIGESTIRCTSDPQGNGV-WSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIG 516
T + L G ++ C G+ V WS P P C + +C AP + Q +
Sbjct: 192 TGYKLFGSTSSFCLI--SGSSVQWSDPLPECREI-YCPAPPQIDNGII--QGERDHYGYR 246
Query: 517 TSLKYECRPEY-YGRPFSITCL---DNLVWSSPKDVCKRKS--CKTPP 558
S+ Y C + SI C D WS P C+ KS K PP
Sbjct: 247 QSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPP 294
Score = 65.9 bits (159), Expect = 4e-10
Identities = 77/288 (26%), Positives = 120/288 (41%), Gaps = 41/288 (14%)
Query: 740 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY-DLRGAA-SMRCTPQGDWS 797
LP+ C PPDV +A+ + +F + Y CE + + G S+ C WS
Sbjct: 29 LPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS 88
Query: 798 PAAPTCEVKSCDDFMGQLLNGRVL---------FPVNLQLGAKVDFVCDEGFQLKGS-SA 847
C +SC+ + LN L FPV G V++ C G++ + S S
Sbjct: 89 DIEEFCN-RSCE--VPTRLNSASLKQPYITQNYFPV----GTVVEYECRPGYRREPSLSP 141
Query: 848 SYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRG 907
L ++ W+++V C++ CP+P I NG+ P + FG ++++C+
Sbjct: 142 KLTCLQNLK--WSTAVEFCKKKSCPNPGEIRNGQ-IDVPGGIL-FGATISFSCN------ 191
Query: 908 TSFDLIGESTIRCTSDPQGNGV-WSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIG 966
T + L G ++ C G+ V WS P P C + +C AP + Q +
Sbjct: 192 TGYKLFGSTSSFCLI--SGSSVQWSDPLPECREI-YCPAPPQIDNGII--QGERDHYGYR 246
Query: 967 TSLKYECRPEY-YGRPFSITCL---DNLVWSSPKDVCKRKS--CKTPP 1008
S+ Y C + SI C D WS P C+ KS K PP
Sbjct: 247 QSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPP 294
Score = 65.5 bits (158), Expect = 5e-10
Identities = 67/269 (24%), Positives = 101/269 (37%), Gaps = 33/269 (12%)
Query: 366 LNGRVLFPVNLQLGAKVDFVCDEGF-QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSP 424
L GR FP + + + C+E F ++ G S L G S W+ C + C P
Sbjct: 49 LEGRTSFPED----TVITYKCEESFVKIPGEKDSVICLKG--SQWSDIEEFCNRS-CEVP 101
Query: 425 PVIPNGRHTGKPL---EVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 481
+ N +P FP G V Y C P R S + C N WS
Sbjct: 102 TRL-NSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLS----PKLTCLQ----NLKWS 152
Query: 482 SPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD- 538
+ C C P ++ G ++ + C Y +G S +
Sbjct: 153 TAVEFCKKKS-CPNPGEIRNGQIDVP---GGILFGATISFSCNTGYKLFGSTSSFCLISG 208
Query: 539 -NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSR--INYSCTTGHRLIGHSSAEC 595
++ WS P C+ C PP NG++ D G R + Y+C G +IG S C
Sbjct: 209 SSVQWSDPLPECREIYCPAPPQIDNGIIQGERD-HYGYRQSVTYACNKGFTMIGEHSIYC 267
Query: 596 ILSGNAAHWSTKPPIC--QRIPCGLPPTI 622
++ + WS PP C + + +PPT+
Sbjct: 268 TVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
Score = 65.5 bits (158), Expect = 5e-10
Identities = 67/269 (24%), Positives = 101/269 (37%), Gaps = 33/269 (12%)
Query: 816 LNGRVLFPVNLQLGAKVDFVCDEGF-QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSP 874
L GR FP + + + C+E F ++ G S L G S W+ C + C P
Sbjct: 49 LEGRTSFPED----TVITYKCEESFVKIPGEKDSVICLKG--SQWSDIEEFCNRS-CEVP 101
Query: 875 PVIPNGRHTGKPL---EVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 931
+ N +P FP G V Y C P R S + C N WS
Sbjct: 102 TRL-NSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLS----PKLTCLQ----NLKWS 152
Query: 932 SPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD- 988
+ C C P ++ G ++ + C Y +G S +
Sbjct: 153 TAVEFCKKKS-CPNPGEIRNGQIDVP---GGILFGATISFSCNTGYKLFGSTSSFCLISG 208
Query: 989 -NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSR--INYSCTTGHRLIGHSSAEC 1045
++ WS P C+ C PP NG++ D G R + Y+C G +IG S C
Sbjct: 209 SSVQWSDPLPECREIYCPAPPQIDNGIIQGERD-HYGYRQSVTYACNKGFTMIGEHSIYC 267
Query: 1046 ILSGNTAHWSTKPPIC--QRIPCGLPPTI 1072
++ + WS PP C + + +PPT+
Sbjct: 268 TVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
Score = 62.4 bits (150), Expect = 4e-09
Identities = 64/247 (25%), Positives = 100/247 (40%), Gaps = 32/247 (12%)
Query: 1735 VSFVCDEGF-RLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPF--- 1790
+++ C+E F ++ G S L G + W+ C + P LN P+
Sbjct: 61 ITYKCEESFVKIPGEKDSVICLKGSQ--WSDIEEFCNRSC--EVPTRLNSASLKQPYITQ 116
Query: 1791 GDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPH 1850
P G + Y C R + + + C N WS+ C+ +CP+
Sbjct: 117 NYFPVGTVVEYECRPGYRREPSLS----PKLTCLQ----NLKWSTAVEFCKKK---SCPN 165
Query: 1851 PPKIQNGHY-IGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGI---WSQLDHYCKE 1906
P +I+NG + G + L G TIS+ C+ GY L G FC G WS C+E
Sbjct: 166 PGEIRNGQIDVPGGI---LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECRE 222
Query: 1907 VNC-SFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADD---RWDPPL 1962
+ C + P NGI + + Y Y VT C G+T+ G C ++ W P
Sbjct: 223 IYCPAPPQIDNGIIQ--GERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPP 280
Query: 1963 AKCTSRT 1969
+C ++
Sbjct: 281 PECRGKS 287
Score = 61.6 bits (148), Expect = 7e-09
Identities = 74/279 (26%), Positives = 113/279 (40%), Gaps = 32/279 (11%)
Query: 1190 LPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGY-DLRGAA-SLHCTPQGDWS 1247
LP+ C PP++ + + + +F + Y CE + + G S+ C WS
Sbjct: 29 LPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS 88
Query: 1248 PEAPRCAVKSCDDFLGQLPHGRVLFPLNLQ----LGAKVSFVCDEGFRLKGSSVSHCVLV 1303
C +SC + +L + P Q +G V + C G+R + S+S +
Sbjct: 89 DIEEFCN-RSC-EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYR-REPSLSPKLTC 145
Query: 1304 GMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLI 1363
W+ +V C+ CPNP I NG+ P G I +G IS++C+ + L
Sbjct: 146 LQNLKWSTAVEFCKKKSCPNPGEIRNGQ-IDVPGG-ILFGATISFSCN------TGYKLF 197
Query: 1364 GESTIRCTSDPHGNGV-WSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSL 1422
G ++ C G+ V WS P P C R +C P Q + I + S+
Sbjct: 198 GSTSSFCLIS--GSSVQWSDPLPEC----REIYCPAPPQID--NGIIQGERDHYGYRQSV 249
Query: 1423 NYECRPGY--FGKMFSISCLENL---VWSSVEDNCRRKS 1456
Y C G+ G+ SI C N WS CR KS
Sbjct: 250 TYACNKGFTMIGE-HSIYCTVNNDEGEWSGPPPECRGKS 287
>gi|27502413 CD46 antigen, complement regulatory protein isoform 7
precursor [Homo sapiens]
Length = 378
Score = 159 bits (402), Expect = 3e-38
Identities = 99/294 (33%), Positives = 138/294 (46%), Gaps = 17/294 (5%)
Query: 25 GSLLAVVVLLALPVAWGQCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYSGRP--- 81
G LLA +VLL + C P + + IG ++Y+C+ GY P
Sbjct: 18 GLLLAAMVLLLYSFS-DACEEPPTFEAMELIGKPKPY-YEIGERVDYKCKKGYFYIPPLA 75
Query: 82 FSIICLKNSVWTGAKD-RCRRKSCRNPPDPVNGMVHVIKGI-QFGSQIKYSCTKGYRLIG 139
IC +N W D C R++C DP+NG G +FG Q+ + C +GY LIG
Sbjct: 76 THTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIG 135
Query: 140 SSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGS 199
C + G IW + PIC+++ C PP I NG + E F Y VTY C+P +
Sbjct: 136 EEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP-A 194
Query: 200 GGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLN 259
G F L+GE +IYC N +WS AP+C + KC P VENG +S F
Sbjct: 195 PGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-KCRFPVVENGKQISGFGKKFYYK 249
Query: 260 EVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQP----PPDVLHAERT 309
V F C GF + G + C + + W+P +P C +V P PP + H+ T
Sbjct: 250 ATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHSVST 303
Score = 154 bits (389), Expect = 8e-37
Identities = 90/258 (34%), Positives = 120/258 (46%), Gaps = 15/258 (5%)
Query: 1416 FPVGTSLNYECRPGYF---GKMFSISCLENLVWSSVEDN-CRRKSCGPPPEPFNGM-VHI 1470
+ +G ++Y+C+ GYF C N W V D+ C R++C +P NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1471 NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDF 1530
N +FG +++ CNEG+ LIG C + G+ W K PICE + C PPP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1531 YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNK 1590
+ F VTY C P G F L+GE +IYC VWS P C K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAP-GPDPFSLIGESTIYCGDN----SVWSRAAPEC-KVVK 227
Query: 1591 CTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVC 1650
C P VEN ++ G F + F C GF + GS T+ C +N W P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVL 287
Query: 1651 QP----PPEILHGEHTLS 1664
P PP + H T S
Sbjct: 288 PPSSTKPPALSHSVSTSS 305
Score = 151 bits (382), Expect = 5e-36
Identities = 90/256 (35%), Positives = 126/256 (49%), Gaps = 15/256 (5%)
Query: 513 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 567
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 568 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDF 627
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 628 ISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 687
+ E F Y VTY C+P + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDP-APGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 688 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC 747
C P VENG +S F V F C GF + G + C + + W+P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVL 287
Query: 748 QP----PPDVLHAERT 759
P PP + H+ T
Sbjct: 288 PPSSTKPPALSHSVST 303
Score = 149 bits (377), Expect = 2e-35
Identities = 90/258 (34%), Positives = 125/258 (48%), Gaps = 15/258 (5%)
Query: 963 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 1017
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1018 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDF 1077
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1078 ISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 1137
+ E F Y VTY C+ + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCD-PAPGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 1138 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC 1197
C P VENG +S F V F C GF + G + C + + W+P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVL 287
Query: 1198 QP----PPEILHGEHTPS 1211
P PP + H T S
Sbjct: 288 PPSSTKPPALSHSVSTSS 305
Score = 130 bits (327), Expect = 1e-29
Identities = 84/265 (31%), Positives = 121/265 (45%), Gaps = 14/265 (5%)
Query: 740 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 797
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 798 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 855
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 856 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGE 915
++W+ P+CE++ C PP I NG+HT +EVF + AV Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 916 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 975
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 976 EYY-GRPFSITCLDNLVWSSPKDVC 999
+Y +I C N W P C
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 129 bits (323), Expect = 4e-29
Identities = 83/265 (31%), Positives = 120/265 (45%), Gaps = 14/265 (5%)
Query: 290 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 347
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 348 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 405
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 406 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGE 465
++W+ P+CE++ C PP I NG+HT +EVF + V Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 466 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 525
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 526 EYY-GRPFSITCLDNLVWSSPKDVC 549
+Y +I C N W P C
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 122 bits (306), Expect = 4e-27
Identities = 77/265 (29%), Positives = 118/265 (44%), Gaps = 14/265 (5%)
Query: 1647 SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLH--CTPQGDWSPEAP 1704
S C+ PP E + + G+ V Y C+ Y + H C W P +
Sbjct: 32 SDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 1705 RCTVKSCDDFLGQLPHGRVLLPLN--LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALW 1762
+ ++ +G+ + P N + G ++ F+C+EG+ L G +C L G A+W
Sbjct: 92 DACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 1763 NSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIR 1822
+ P+CE++ C PP I NG+HT + Y ++Y+CD P F+LIGES+I
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIY 209
Query: 1823 CTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYL 1882
C N VWS AP C++ C P ++NG I G + T+ + CD G+
Sbjct: 210 CGD----NSVWSRAAPECKV---VKCRF-PVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1883 LVGKGFIFCTDQGIWSQLDHYCKEV 1907
L G I C W C +V
Sbjct: 262 LDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 114 bits (286), Expect = 7e-25
Identities = 79/270 (29%), Positives = 120/270 (44%), Gaps = 21/270 (7%)
Query: 1190 LPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH--CTPQGDWS 1247
L S S C+ PP E + + G+ V Y C+ GY + H C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 1248 PEAPRCAVKSCDDFLGQLPHGRVLFPLN--LQLGAKVSFVCDEGFRLKGSSVSHCVLVGM 1305
P + + ++ +G+ + P N + G ++ F+C+EG+ L G + +C L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
++W+ P+CE + C PP I NG+HT + Y ++Y+CDP P F+LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGE 205
Query: 1366 STIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDF--EFPVGTSLN 1423
STI C N VWS AP C++ C+ FP I+ F +F ++
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV----KCR----FPVVENGKQISGFGKKFYYKATVM 253
Query: 1424 YECRPG-YFGKMFSISCLENLVWSSVEDNC 1452
+EC G Y +I C N W C
Sbjct: 254 FECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 110 bits (274), Expect = 2e-23
Identities = 70/243 (28%), Positives = 115/243 (47%), Gaps = 21/243 (8%)
Query: 1730 QLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTP 1789
++G +V + C +G+ A+H + S C + CP LNG+
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1790 FGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGN-GVWSSPAPRCELSVPAAC 1848
G +G ++ + C+ + LIGE + C + +G+ +WS P CE C
Sbjct: 115 -GTYEFGYQMHFICNEG------YYLIGEEILYC--ELKGSVAIWSGKPPICE---KVLC 162
Query: 1849 PHPPKIQNGHYIGGHVSLYLPGMTISYICDPG-----YLLVGKGFIFCTDQGIWSQLDHY 1903
PPKI+NG + V ++ ++Y CDP + L+G+ I+C D +WS+
Sbjct: 163 TPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPE 222
Query: 1904 CKEVNCSFPLFMNGISKELE-MKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPL 1962
CK V C FP+ NG K++ K ++Y V +C+ G+ L+GS C ++ WDPP+
Sbjct: 223 CKVVKCRFPVVENG--KQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 1963 AKC 1965
KC
Sbjct: 281 PKC 283
Score = 90.5 bits (223), Expect = 2e-17
Identities = 83/314 (26%), Positives = 128/314 (40%), Gaps = 37/314 (11%)
Query: 1066 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1125
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 1126 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 1181
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 1182 --ALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPG-----YDLR 1233
++ W + P C +V C PPP+I +G+HT S + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1234 GAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVL--FPLNLQLGAKVSFVCDEGFR 1291
G ++++C WS AP C V C + +G+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1292 LKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPN---PPAILNGRHTGTPSGDIPYGKEISY 1348
L GS C S W+ VP C + P+ PPA+ + T + + P Y
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKCLKVLPPSSTKPPALSHSVSTSSTTKS-PASSASGY 317
Query: 1349 TCDPHPDRGMTFNL 1362
P P+ G+ +L
Sbjct: 318 ---PKPEEGILDSL 328
Score = 87.8 bits (216), Expect = 1e-16
Identities = 58/237 (24%), Positives = 90/237 (37%), Gaps = 13/237 (5%)
Query: 1022 QVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTN 1081
++G R++Y C G+ I + I N C R C NG + N
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1082 RENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP 1141
+ +G + + CN G + L+GE +YC V IWSG P C PP
Sbjct: 115 G-TYEFGYQMHFICNEG------YYLIGEEILYCELKGS-VAIWSGKPPICEKVLCTPPP 166
Query: 1142 NVENGILVSDNRSLFSLNEVVEFRCQPG-----FVMKGPRRVKCQALNKWEPELPSCSRV 1196
++NG +F + V + C P F + G + C + W P C V
Sbjct: 167 KIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVV 226
Query: 1197 CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1253
P + +G+ F V + C+ G+ L G+ ++ C W P P+C
Sbjct: 227 KCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 87.0 bits (214), Expect = 2e-16
Identities = 81/309 (26%), Positives = 123/309 (39%), Gaps = 37/309 (11%)
Query: 616 CGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 675
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 676 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 731
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 732 --ALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG-----YDLR 783
++ W + P C +V C PPP + + + T + + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 784 GAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVL--FPVNLQLGAKVDFVCDEGFQ 841
G +++ C WS AAP C+V C + NG+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 842 LKGSSASYCVLAGMESLWNSSVPVCEQIFCPS---PPVIPNGRHTGKPLEVFPFGKAVNY 898
L GS C S W+ VP C ++ PS PP + + T + P A Y
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKCLKVLPPSSTKPPALSHSVSTSSTTK-SPASSASGY 317
Query: 899 TCDPHPDRG 907
P P+ G
Sbjct: 318 ---PKPEEG 323
Score = 85.5 bits (210), Expect = 5e-16
Identities = 80/309 (25%), Positives = 121/309 (39%), Gaps = 37/309 (11%)
Query: 166 CGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 225
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 226 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 282
+ C P + NG V N + + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPANGT-YEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 283 LNK---WEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG-----YDLR 333
W + P C +V C PPP + + + T + + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 334 GAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVL--FPVNLQLGAKVDFVCDEGFQ 391
G +++ C WS AAP C+V C + NG+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 392 LKGSSASYCVLAGMESLWNSSVPVCEQIFCPS---PPVIPNGRHTGKPLEVFPFGKTVNY 448
L GS C S W+ VP C ++ PS PP + + T + P Y
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKCLKVLPPSSTKPPALSHSVSTSSTTK-SPASSASGY 317
Query: 449 TCDPHPDRG 457
P P+ G
Sbjct: 318 ---PKPEEG 323
Score = 85.1 bits (209), Expect = 6e-16
Identities = 64/260 (24%), Positives = 98/260 (37%), Gaps = 19/260 (7%)
Query: 1456 SCGPPPEPFNGMVHINTDTQF---GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTW-DKKA 1511
+C PP F M I + G V+Y C +G+ I P T + N TW
Sbjct: 34 ACEEPPT-FEAMELIGKPKPYYEIGERVDYKCKKGYFYI-PPLATHTICDRNHTWLPVSD 91
Query: 1512 PICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSK 1571
C +C NG N T + G + + C+ G + L+GE +YC K
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGT-YEFGYQMHFICNEG------YYLIGEEILYCELK 144
Query: 1572 DDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPG-----FVMV 1626
V +WS PP C P+++N F + + + C P F ++
Sbjct: 145 GS-VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1627 GSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLR 1686
G T+ C N W P C V P + +G+ F V + C+ + L
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLD 263
Query: 1687 GAASLHCTPQGDWSPEAPRC 1706
G+ ++ C W P P+C
Sbjct: 264 GSDTIVCDSNSTWDPPVPKC 283
Score = 73.2 bits (178), Expect = 2e-12
Identities = 66/262 (25%), Positives = 108/262 (41%), Gaps = 30/262 (11%)
Query: 1140 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP--RRVKCQALNKWEP-ELPSCSR- 1195
PP E L+ + + + E V+++C+ G+ P C + W P +C R
Sbjct: 38 PPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRE 97
Query: 1196 VCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD---WSPEAPR 1252
C + L+G+ P++ + G ++ + C GY L G L+C +G WS + P
Sbjct: 98 TCPYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPI 156
Query: 1253 CAVKSCDDFLGQLPHGRVLFP--LNLQLGAKVSFVCD-----EGFRLKGSSVSHCVLVGM 1305
C C ++ +G+ F + V++ CD + F L G S +C G
Sbjct: 157 CEKVLCTP-PPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC---GD 212
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
S+W+ + P C+ + C P + NG+ Y + + CD F L G
Sbjct: 213 NSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECD------KGFYLDGS 265
Query: 1366 STIRCTSDPHGNGVWSSPAPRC 1387
TI C S N W P P+C
Sbjct: 266 DTIVCDS----NSTWDPPVPKC 283
Score = 68.6 bits (166), Expect = 6e-11
Identities = 67/285 (23%), Positives = 118/285 (41%), Gaps = 33/285 (11%)
Query: 1588 TNKCTAPEVENAIRVPGN-RSFFTLTEIIRFRCQPGFVMV---GSHTVQCQTNGRWGPKL 1643
++ C P A+ + G + ++ + E + ++C+ G+ + +HT+ C N W P
Sbjct: 32 SDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTI-CDRNHTWLPVS 90
Query: 1644 PH-CSR-VCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGD--- 1698
C R C + L+G+ + + G ++ + C Y L G L+C +G
Sbjct: 91 DDACYRETCPYIRDPLNGQ-AVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 1699 WSPEAPRCTVKSCDD--FLGQLPHGRVLLPLNLQLGAKVSFVCD-----EGFRLKGRSAS 1751
WS + P C C + H + + L A V++ CD + F L G S
Sbjct: 150 WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDA-VTYSCDPAPGPDPFSLIGESTI 208
Query: 1752 HCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGM 1811
+C G ++W+ + P C+ + C P + NG+ +GK+ Y +
Sbjct: 209 YC---GDNSVWSRAAPECKVVKC-RFPVVENGKQISG------FGKKFYYKATVMFECDK 258
Query: 1812 TFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQN 1856
F L G +I C S N W P P+C +P + PP + +
Sbjct: 259 GFYLDGSDTIVCDS----NSTWDPPVPKCLKVLPPSSTKPPALSH 299
>gi|27502402 CD46 antigen, complement regulatory protein isoform 1
precursor [Homo sapiens]
Length = 392
Score = 159 bits (402), Expect = 3e-38
Identities = 99/294 (33%), Positives = 138/294 (46%), Gaps = 17/294 (5%)
Query: 25 GSLLAVVVLLALPVAWGQCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYSGRP--- 81
G LLA +VLL + C P + + IG ++Y+C+ GY P
Sbjct: 18 GLLLAAMVLLLYSFS-DACEEPPTFEAMELIGKPKPY-YEIGERVDYKCKKGYFYIPPLA 75
Query: 82 FSIICLKNSVWTGAKD-RCRRKSCRNPPDPVNGMVHVIKGI-QFGSQIKYSCTKGYRLIG 139
IC +N W D C R++C DP+NG G +FG Q+ + C +GY LIG
Sbjct: 76 THTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIG 135
Query: 140 SSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGS 199
C + G IW + PIC+++ C PP I NG + E F Y VTY C+P +
Sbjct: 136 EEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP-A 194
Query: 200 GGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLN 259
G F L+GE +IYC N +WS AP+C + KC P VENG +S F
Sbjct: 195 PGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-KCRFPVVENGKQISGFGKKFYYK 249
Query: 260 EVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQP----PPDVLHAERT 309
V F C GF + G + C + + W+P +P C +V P PP + H+ T
Sbjct: 250 ATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHSVST 303
Score = 154 bits (389), Expect = 8e-37
Identities = 90/258 (34%), Positives = 120/258 (46%), Gaps = 15/258 (5%)
Query: 1416 FPVGTSLNYECRPGYF---GKMFSISCLENLVWSSVEDN-CRRKSCGPPPEPFNGM-VHI 1470
+ +G ++Y+C+ GYF C N W V D+ C R++C +P NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1471 NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDF 1530
N +FG +++ CNEG+ LIG C + G+ W K PICE + C PPP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1531 YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNK 1590
+ F VTY C P G F L+GE +IYC VWS P C K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAP-GPDPFSLIGESTIYCGDN----SVWSRAAPEC-KVVK 227
Query: 1591 CTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVC 1650
C P VEN ++ G F + F C GF + GS T+ C +N W P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVL 287
Query: 1651 QP----PPEILHGEHTLS 1664
P PP + H T S
Sbjct: 288 PPSSTKPPALSHSVSTSS 305
Score = 151 bits (382), Expect = 5e-36
Identities = 90/256 (35%), Positives = 126/256 (49%), Gaps = 15/256 (5%)
Query: 513 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 567
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 568 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDF 627
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 628 ISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 687
+ E F Y VTY C+P + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDP-APGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 688 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC 747
C P VENG +S F V F C GF + G + C + + W+P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVL 287
Query: 748 QP----PPDVLHAERT 759
P PP + H+ T
Sbjct: 288 PPSSTKPPALSHSVST 303
Score = 149 bits (377), Expect = 2e-35
Identities = 90/258 (34%), Positives = 125/258 (48%), Gaps = 15/258 (5%)
Query: 963 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 1017
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1018 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDF 1077
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1078 ISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 1137
+ E F Y VTY C+ + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCD-PAPGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 1138 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC 1197
C P VENG +S F V F C GF + G + C + + W+P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVL 287
Query: 1198 QP----PPEILHGEHTPS 1211
P PP + H T S
Sbjct: 288 PPSSTKPPALSHSVSTSS 305
Score = 130 bits (327), Expect = 1e-29
Identities = 84/265 (31%), Positives = 121/265 (45%), Gaps = 14/265 (5%)
Query: 740 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 797
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 798 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 855
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 856 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGE 915
++W+ P+CE++ C PP I NG+HT +EVF + AV Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 916 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 975
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 976 EYY-GRPFSITCLDNLVWSSPKDVC 999
+Y +I C N W P C
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 129 bits (323), Expect = 4e-29
Identities = 83/265 (31%), Positives = 120/265 (45%), Gaps = 14/265 (5%)
Query: 290 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 347
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 348 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 405
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 406 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGE 465
++W+ P+CE++ C PP I NG+HT +EVF + V Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 466 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 525
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 526 EYY-GRPFSITCLDNLVWSSPKDVC 549
+Y +I C N W P C
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 122 bits (306), Expect = 4e-27
Identities = 77/265 (29%), Positives = 118/265 (44%), Gaps = 14/265 (5%)
Query: 1647 SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLH--CTPQGDWSPEAP 1704
S C+ PP E + + G+ V Y C+ Y + H C W P +
Sbjct: 32 SDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 1705 RCTVKSCDDFLGQLPHGRVLLPLN--LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALW 1762
+ ++ +G+ + P N + G ++ F+C+EG+ L G +C L G A+W
Sbjct: 92 DACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 1763 NSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIR 1822
+ P+CE++ C PP I NG+HT + Y ++Y+CD P F+LIGES+I
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIY 209
Query: 1823 CTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYL 1882
C N VWS AP C++ C P ++NG I G + T+ + CD G+
Sbjct: 210 CGD----NSVWSRAAPECKV---VKCRF-PVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1883 LVGKGFIFCTDQGIWSQLDHYCKEV 1907
L G I C W C +V
Sbjct: 262 LDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 114 bits (286), Expect = 7e-25
Identities = 79/270 (29%), Positives = 120/270 (44%), Gaps = 21/270 (7%)
Query: 1190 LPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH--CTPQGDWS 1247
L S S C+ PP E + + G+ V Y C+ GY + H C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 1248 PEAPRCAVKSCDDFLGQLPHGRVLFPLN--LQLGAKVSFVCDEGFRLKGSSVSHCVLVGM 1305
P + + ++ +G+ + P N + G ++ F+C+EG+ L G + +C L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
++W+ P+CE + C PP I NG+HT + Y ++Y+CDP P F+LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGE 205
Query: 1366 STIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDF--EFPVGTSLN 1423
STI C N VWS AP C++ C+ FP I+ F +F ++
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV----KCR----FPVVENGKQISGFGKKFYYKATVM 253
Query: 1424 YECRPG-YFGKMFSISCLENLVWSSVEDNC 1452
+EC G Y +I C N W C
Sbjct: 254 FECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 110 bits (274), Expect = 2e-23
Identities = 70/243 (28%), Positives = 115/243 (47%), Gaps = 21/243 (8%)
Query: 1730 QLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTP 1789
++G +V + C +G+ A+H + S C + CP LNG+
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1790 FGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGN-GVWSSPAPRCELSVPAAC 1848
G +G ++ + C+ + LIGE + C + +G+ +WS P CE C
Sbjct: 115 -GTYEFGYQMHFICNEG------YYLIGEEILYC--ELKGSVAIWSGKPPICE---KVLC 162
Query: 1849 PHPPKIQNGHYIGGHVSLYLPGMTISYICDPG-----YLLVGKGFIFCTDQGIWSQLDHY 1903
PPKI+NG + V ++ ++Y CDP + L+G+ I+C D +WS+
Sbjct: 163 TPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPE 222
Query: 1904 CKEVNCSFPLFMNGISKELE-MKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPL 1962
CK V C FP+ NG K++ K ++Y V +C+ G+ L+GS C ++ WDPP+
Sbjct: 223 CKVVKCRFPVVENG--KQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 1963 AKC 1965
KC
Sbjct: 281 PKC 283
Score = 89.7 bits (221), Expect = 3e-17
Identities = 87/324 (26%), Positives = 132/324 (40%), Gaps = 43/324 (13%)
Query: 1066 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1125
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 1126 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 1181
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 1182 --ALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPG-----YDLR 1233
++ W + P C +V C PPP+I +G+HT S + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1234 GAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVL--FPLNLQLGAKVSFVCDEGFR 1291
G ++++C WS AP C V C + +G+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1292 LKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPN---PPAILNGRHT--------GTPSGDI 1340
L GS C S W+ VP C + P+ PPA+ + T + SG
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKCLKVLPPSSTKPPALSHSVSTSSTTKSPASSASGPR 318
Query: 1341 P-YGKEIS-YTCDPHPDRGMTFNL 1362
P Y +S Y P P+ G+ +L
Sbjct: 319 PTYKPPVSNYPGYPKPEEGILDSL 342
Score = 87.8 bits (216), Expect = 1e-16
Identities = 58/237 (24%), Positives = 90/237 (37%), Gaps = 13/237 (5%)
Query: 1022 QVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTN 1081
++G R++Y C G+ I + I N C R C NG + N
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1082 RENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP 1141
+ +G + + CN G + L+GE +YC V IWSG P C PP
Sbjct: 115 G-TYEFGYQMHFICNEG------YYLIGEEILYCELKGS-VAIWSGKPPICEKVLCTPPP 166
Query: 1142 NVENGILVSDNRSLFSLNEVVEFRCQPG-----FVMKGPRRVKCQALNKWEPELPSCSRV 1196
++NG +F + V + C P F + G + C + W P C V
Sbjct: 167 KIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVV 226
Query: 1197 CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1253
P + +G+ F V + C+ G+ L G+ ++ C W P P+C
Sbjct: 227 KCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 85.1 bits (209), Expect = 6e-16
Identities = 64/260 (24%), Positives = 98/260 (37%), Gaps = 19/260 (7%)
Query: 1456 SCGPPPEPFNGMVHINTDTQF---GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTW-DKKA 1511
+C PP F M I + G V+Y C +G+ I P T + N TW
Sbjct: 34 ACEEPPT-FEAMELIGKPKPYYEIGERVDYKCKKGYFYI-PPLATHTICDRNHTWLPVSD 91
Query: 1512 PICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSK 1571
C +C NG N T + G + + C+ G + L+GE +YC K
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGT-YEFGYQMHFICNEG------YYLIGEEILYCELK 144
Query: 1572 DDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPG-----FVMV 1626
V +WS PP C P+++N F + + + C P F ++
Sbjct: 145 GS-VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1627 GSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLR 1686
G T+ C N W P C V P + +G+ F V + C+ + L
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLD 263
Query: 1687 GAASLHCTPQGDWSPEAPRC 1706
G+ ++ C W P P+C
Sbjct: 264 GSDTIVCDSNSTWDPPVPKC 283
Score = 84.7 bits (208), Expect = 8e-16
Identities = 75/285 (26%), Positives = 114/285 (40%), Gaps = 33/285 (11%)
Query: 166 CGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 225
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 226 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 282
+ C P + NG V N + + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPANGT-YEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 283 LNK---WEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG-----YDLR 333
W + P C +V C PPP + + + T + + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 334 GAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVL--FPVNLQLGAKVDFVCDEGFQ 391
G +++ C WS AAP C+V C + NG+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 392 LKGSSASYCVLAGMESLWNSSVPVCEQIFCPS---PPVIPNGRHT 433
L GS C S W+ VP C ++ PS PP + + T
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKCLKVLPPSSTKPPALSHSVST 303
Score = 84.7 bits (208), Expect = 8e-16
Identities = 75/285 (26%), Positives = 115/285 (40%), Gaps = 33/285 (11%)
Query: 616 CGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 675
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 676 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 731
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 732 --ALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG-----YDLR 783
++ W + P C +V C PPP + + + T + + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 784 GAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVL--FPVNLQLGAKVDFVCDEGFQ 841
G +++ C WS AAP C+V C + NG+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 842 LKGSSASYCVLAGMESLWNSSVPVCEQIFCPS---PPVIPNGRHT 883
L GS C S W+ VP C ++ PS PP + + T
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKCLKVLPPSSTKPPALSHSVST 303
Score = 73.2 bits (178), Expect = 2e-12
Identities = 66/262 (25%), Positives = 108/262 (41%), Gaps = 30/262 (11%)
Query: 1140 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP--RRVKCQALNKWEP-ELPSCSR- 1195
PP E L+ + + + E V+++C+ G+ P C + W P +C R
Sbjct: 38 PPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRE 97
Query: 1196 VCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD---WSPEAPR 1252
C + L+G+ P++ + G ++ + C GY L G L+C +G WS + P
Sbjct: 98 TCPYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPI 156
Query: 1253 CAVKSCDDFLGQLPHGRVLFP--LNLQLGAKVSFVCD-----EGFRLKGSSVSHCVLVGM 1305
C C ++ +G+ F + V++ CD + F L G S +C G
Sbjct: 157 CEKVLCTP-PPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC---GD 212
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
S+W+ + P C+ + C P + NG+ Y + + CD F L G
Sbjct: 213 NSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECD------KGFYLDGS 265
Query: 1366 STIRCTSDPHGNGVWSSPAPRC 1387
TI C S N W P P+C
Sbjct: 266 DTIVCDS----NSTWDPPVPKC 283
Score = 68.6 bits (166), Expect = 6e-11
Identities = 67/285 (23%), Positives = 118/285 (41%), Gaps = 33/285 (11%)
Query: 1588 TNKCTAPEVENAIRVPGN-RSFFTLTEIIRFRCQPGFVMV---GSHTVQCQTNGRWGPKL 1643
++ C P A+ + G + ++ + E + ++C+ G+ + +HT+ C N W P
Sbjct: 32 SDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTI-CDRNHTWLPVS 90
Query: 1644 PH-CSR-VCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGD--- 1698
C R C + L+G+ + + G ++ + C Y L G L+C +G
Sbjct: 91 DDACYRETCPYIRDPLNGQ-AVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 1699 WSPEAPRCTVKSCDD--FLGQLPHGRVLLPLNLQLGAKVSFVCD-----EGFRLKGRSAS 1751
WS + P C C + H + + L A V++ CD + F L G S
Sbjct: 150 WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDA-VTYSCDPAPGPDPFSLIGESTI 208
Query: 1752 HCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGM 1811
+C G ++W+ + P C+ + C P + NG+ +GK+ Y +
Sbjct: 209 YC---GDNSVWSRAAPECKVVKC-RFPVVENGKQISG------FGKKFYYKATVMFECDK 258
Query: 1812 TFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQN 1856
F L G +I C S N W P P+C +P + PP + +
Sbjct: 259 GFYLDGSDTIVCDS----NSTWDPPVPKCLKVLPPSSTKPPALSH 299
>gi|27502425 CD46 antigen, complement regulatory protein isoform 8
precursor [Homo sapiens]
Length = 385
Score = 159 bits (402), Expect = 3e-38
Identities = 99/294 (33%), Positives = 138/294 (46%), Gaps = 17/294 (5%)
Query: 25 GSLLAVVVLLALPVAWGQCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYSGRP--- 81
G LLA +VLL + C P + + IG ++Y+C+ GY P
Sbjct: 18 GLLLAAMVLLLYSFS-DACEEPPTFEAMELIGKPKPY-YEIGERVDYKCKKGYFYIPPLA 75
Query: 82 FSIICLKNSVWTGAKD-RCRRKSCRNPPDPVNGMVHVIKGI-QFGSQIKYSCTKGYRLIG 139
IC +N W D C R++C DP+NG G +FG Q+ + C +GY LIG
Sbjct: 76 THTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIG 135
Query: 140 SSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGS 199
C + G IW + PIC+++ C PP I NG + E F Y VTY C+P +
Sbjct: 136 EEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP-A 194
Query: 200 GGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLN 259
G F L+GE +IYC N +WS AP+C + KC P VENG +S F
Sbjct: 195 PGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-KCRFPVVENGKQISGFGKKFYYK 249
Query: 260 EVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQP----PPDVLHAERT 309
V F C GF + G + C + + W+P +P C +V P PP + H+ T
Sbjct: 250 ATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHSVST 303
Score = 154 bits (389), Expect = 8e-37
Identities = 90/258 (34%), Positives = 120/258 (46%), Gaps = 15/258 (5%)
Query: 1416 FPVGTSLNYECRPGYF---GKMFSISCLENLVWSSVEDN-CRRKSCGPPPEPFNGM-VHI 1470
+ +G ++Y+C+ GYF C N W V D+ C R++C +P NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1471 NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDF 1530
N +FG +++ CNEG+ LIG C + G+ W K PICE + C PPP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1531 YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNK 1590
+ F VTY C P G F L+GE +IYC VWS P C K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAP-GPDPFSLIGESTIYCGDN----SVWSRAAPEC-KVVK 227
Query: 1591 CTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVC 1650
C P VEN ++ G F + F C GF + GS T+ C +N W P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVL 287
Query: 1651 QP----PPEILHGEHTLS 1664
P PP + H T S
Sbjct: 288 PPSSTKPPALSHSVSTSS 305
Score = 151 bits (382), Expect = 5e-36
Identities = 90/256 (35%), Positives = 126/256 (49%), Gaps = 15/256 (5%)
Query: 513 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 567
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 568 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDF 627
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 628 ISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 687
+ E F Y VTY C+P + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDP-APGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 688 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC 747
C P VENG +S F V F C GF + G + C + + W+P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVL 287
Query: 748 QP----PPDVLHAERT 759
P PP + H+ T
Sbjct: 288 PPSSTKPPALSHSVST 303
Score = 149 bits (377), Expect = 2e-35
Identities = 90/258 (34%), Positives = 125/258 (48%), Gaps = 15/258 (5%)
Query: 963 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 1017
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1018 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDF 1077
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1078 ISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 1137
+ E F Y VTY C+ + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCD-PAPGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 1138 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC 1197
C P VENG +S F V F C GF + G + C + + W+P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVL 287
Query: 1198 QP----PPEILHGEHTPS 1211
P PP + H T S
Sbjct: 288 PPSSTKPPALSHSVSTSS 305
Score = 130 bits (327), Expect = 1e-29
Identities = 84/265 (31%), Positives = 121/265 (45%), Gaps = 14/265 (5%)
Query: 740 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 797
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 798 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 855
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 856 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGE 915
++W+ P+CE++ C PP I NG+HT +EVF + AV Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 916 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 975
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 976 EYY-GRPFSITCLDNLVWSSPKDVC 999
+Y +I C N W P C
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 129 bits (323), Expect = 4e-29
Identities = 83/265 (31%), Positives = 120/265 (45%), Gaps = 14/265 (5%)
Query: 290 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 347
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 348 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 405
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 406 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGE 465
++W+ P+CE++ C PP I NG+HT +EVF + V Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 466 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 525
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 526 EYY-GRPFSITCLDNLVWSSPKDVC 549
+Y +I C N W P C
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 122 bits (306), Expect = 4e-27
Identities = 77/265 (29%), Positives = 118/265 (44%), Gaps = 14/265 (5%)
Query: 1647 SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLH--CTPQGDWSPEAP 1704
S C+ PP E + + G+ V Y C+ Y + H C W P +
Sbjct: 32 SDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 1705 RCTVKSCDDFLGQLPHGRVLLPLN--LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALW 1762
+ ++ +G+ + P N + G ++ F+C+EG+ L G +C L G A+W
Sbjct: 92 DACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 1763 NSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIR 1822
+ P+CE++ C PP I NG+HT + Y ++Y+CD P F+LIGES+I
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIY 209
Query: 1823 CTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYL 1882
C N VWS AP C++ C P ++NG I G + T+ + CD G+
Sbjct: 210 CGD----NSVWSRAAPECKV---VKCRF-PVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1883 LVGKGFIFCTDQGIWSQLDHYCKEV 1907
L G I C W C +V
Sbjct: 262 LDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 114 bits (286), Expect = 7e-25
Identities = 79/270 (29%), Positives = 120/270 (44%), Gaps = 21/270 (7%)
Query: 1190 LPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH--CTPQGDWS 1247
L S S C+ PP E + + G+ V Y C+ GY + H C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 1248 PEAPRCAVKSCDDFLGQLPHGRVLFPLN--LQLGAKVSFVCDEGFRLKGSSVSHCVLVGM 1305
P + + ++ +G+ + P N + G ++ F+C+EG+ L G + +C L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
++W+ P+CE + C PP I NG+HT + Y ++Y+CDP P F+LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGE 205
Query: 1366 STIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDF--EFPVGTSLN 1423
STI C N VWS AP C++ C+ FP I+ F +F ++
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV----KCR----FPVVENGKQISGFGKKFYYKATVM 253
Query: 1424 YECRPG-YFGKMFSISCLENLVWSSVEDNC 1452
+EC G Y +I C N W C
Sbjct: 254 FECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 110 bits (274), Expect = 2e-23
Identities = 70/243 (28%), Positives = 115/243 (47%), Gaps = 21/243 (8%)
Query: 1730 QLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTP 1789
++G +V + C +G+ A+H + S C + CP LNG+
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1790 FGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGN-GVWSSPAPRCELSVPAAC 1848
G +G ++ + C+ + LIGE + C + +G+ +WS P CE C
Sbjct: 115 -GTYEFGYQMHFICNEG------YYLIGEEILYC--ELKGSVAIWSGKPPICE---KVLC 162
Query: 1849 PHPPKIQNGHYIGGHVSLYLPGMTISYICDPG-----YLLVGKGFIFCTDQGIWSQLDHY 1903
PPKI+NG + V ++ ++Y CDP + L+G+ I+C D +WS+
Sbjct: 163 TPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPE 222
Query: 1904 CKEVNCSFPLFMNGISKELE-MKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPL 1962
CK V C FP+ NG K++ K ++Y V +C+ G+ L+GS C ++ WDPP+
Sbjct: 223 CKVVKCRFPVVENG--KQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 1963 AKC 1965
KC
Sbjct: 281 PKC 283
Score = 90.5 bits (223), Expect = 2e-17
Identities = 83/314 (26%), Positives = 128/314 (40%), Gaps = 37/314 (11%)
Query: 1066 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1125
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 1126 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 1181
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 1182 --ALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPG-----YDLR 1233
++ W + P C +V C PPP+I +G+HT S + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1234 GAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVL--FPLNLQLGAKVSFVCDEGFR 1291
G ++++C WS AP C V C + +G+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1292 LKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPN---PPAILNGRHTGTPSGDIPYGKEISY 1348
L GS C S W+ VP C + P+ PPA+ + T + + P Y
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKCLKVLPPSSTKPPALSHSVSTSSTTKS-PASSASGY 317
Query: 1349 TCDPHPDRGMTFNL 1362
P P+ G+ +L
Sbjct: 318 ---PKPEEGILDSL 328
Score = 87.8 bits (216), Expect = 1e-16
Identities = 58/237 (24%), Positives = 90/237 (37%), Gaps = 13/237 (5%)
Query: 1022 QVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTN 1081
++G R++Y C G+ I + I N C R C NG + N
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1082 RENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP 1141
+ +G + + CN G + L+GE +YC V IWSG P C PP
Sbjct: 115 G-TYEFGYQMHFICNEG------YYLIGEEILYCELKGS-VAIWSGKPPICEKVLCTPPP 166
Query: 1142 NVENGILVSDNRSLFSLNEVVEFRCQPG-----FVMKGPRRVKCQALNKWEPELPSCSRV 1196
++NG +F + V + C P F + G + C + W P C V
Sbjct: 167 KIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVV 226
Query: 1197 CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1253
P + +G+ F V + C+ G+ L G+ ++ C W P P+C
Sbjct: 227 KCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 87.0 bits (214), Expect = 2e-16
Identities = 81/309 (26%), Positives = 123/309 (39%), Gaps = 37/309 (11%)
Query: 616 CGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 675
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 676 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 731
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 732 --ALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG-----YDLR 783
++ W + P C +V C PPP + + + T + + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 784 GAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVL--FPVNLQLGAKVDFVCDEGFQ 841
G +++ C WS AAP C+V C + NG+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 842 LKGSSASYCVLAGMESLWNSSVPVCEQIFCPS---PPVIPNGRHTGKPLEVFPFGKAVNY 898
L GS C S W+ VP C ++ PS PP + + T + P A Y
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKCLKVLPPSSTKPPALSHSVSTSSTTK-SPASSASGY 317
Query: 899 TCDPHPDRG 907
P P+ G
Sbjct: 318 ---PKPEEG 323
Score = 85.5 bits (210), Expect = 5e-16
Identities = 80/309 (25%), Positives = 121/309 (39%), Gaps = 37/309 (11%)
Query: 166 CGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 225
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 226 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 282
+ C P + NG V N + + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPANGT-YEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 283 LNK---WEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG-----YDLR 333
W + P C +V C PPP + + + T + + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 334 GAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVL--FPVNLQLGAKVDFVCDEGFQ 391
G +++ C WS AAP C+V C + NG+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 392 LKGSSASYCVLAGMESLWNSSVPVCEQIFCPS---PPVIPNGRHTGKPLEVFPFGKTVNY 448
L GS C S W+ VP C ++ PS PP + + T + P Y
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKCLKVLPPSSTKPPALSHSVSTSSTTK-SPASSASGY 317
Query: 449 TCDPHPDRG 457
P P+ G
Sbjct: 318 ---PKPEEG 323
Score = 85.1 bits (209), Expect = 6e-16
Identities = 64/260 (24%), Positives = 98/260 (37%), Gaps = 19/260 (7%)
Query: 1456 SCGPPPEPFNGMVHINTDTQF---GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTW-DKKA 1511
+C PP F M I + G V+Y C +G+ I P T + N TW
Sbjct: 34 ACEEPPT-FEAMELIGKPKPYYEIGERVDYKCKKGYFYI-PPLATHTICDRNHTWLPVSD 91
Query: 1512 PICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSK 1571
C +C NG N T + G + + C+ G + L+GE +YC K
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGT-YEFGYQMHFICNEG------YYLIGEEILYCELK 144
Query: 1572 DDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPG-----FVMV 1626
V +WS PP C P+++N F + + + C P F ++
Sbjct: 145 GS-VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1627 GSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLR 1686
G T+ C N W P C V P + +G+ F V + C+ + L
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLD 263
Query: 1687 GAASLHCTPQGDWSPEAPRC 1706
G+ ++ C W P P+C
Sbjct: 264 GSDTIVCDSNSTWDPPVPKC 283
Score = 73.2 bits (178), Expect = 2e-12
Identities = 66/262 (25%), Positives = 108/262 (41%), Gaps = 30/262 (11%)
Query: 1140 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP--RRVKCQALNKWEP-ELPSCSR- 1195
PP E L+ + + + E V+++C+ G+ P C + W P +C R
Sbjct: 38 PPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRE 97
Query: 1196 VCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD---WSPEAPR 1252
C + L+G+ P++ + G ++ + C GY L G L+C +G WS + P
Sbjct: 98 TCPYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPI 156
Query: 1253 CAVKSCDDFLGQLPHGRVLFP--LNLQLGAKVSFVCD-----EGFRLKGSSVSHCVLVGM 1305
C C ++ +G+ F + V++ CD + F L G S +C G
Sbjct: 157 CEKVLCTP-PPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC---GD 212
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
S+W+ + P C+ + C P + NG+ Y + + CD F L G
Sbjct: 213 NSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECD------KGFYLDGS 265
Query: 1366 STIRCTSDPHGNGVWSSPAPRC 1387
TI C S N W P P+C
Sbjct: 266 DTIVCDS----NSTWDPPVPKC 283
Score = 68.6 bits (166), Expect = 6e-11
Identities = 67/285 (23%), Positives = 118/285 (41%), Gaps = 33/285 (11%)
Query: 1588 TNKCTAPEVENAIRVPGN-RSFFTLTEIIRFRCQPGFVMV---GSHTVQCQTNGRWGPKL 1643
++ C P A+ + G + ++ + E + ++C+ G+ + +HT+ C N W P
Sbjct: 32 SDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTI-CDRNHTWLPVS 90
Query: 1644 PH-CSR-VCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGD--- 1698
C R C + L+G+ + + G ++ + C Y L G L+C +G
Sbjct: 91 DDACYRETCPYIRDPLNGQ-AVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 1699 WSPEAPRCTVKSCDD--FLGQLPHGRVLLPLNLQLGAKVSFVCD-----EGFRLKGRSAS 1751
WS + P C C + H + + L A V++ CD + F L G S
Sbjct: 150 WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDA-VTYSCDPAPGPDPFSLIGESTI 208
Query: 1752 HCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGM 1811
+C G ++W+ + P C+ + C P + NG+ +GK+ Y +
Sbjct: 209 YC---GDNSVWSRAAPECKVVKC-RFPVVENGKQISG------FGKKFYYKATVMFECDK 258
Query: 1812 TFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQN 1856
F L G +I C S N W P P+C +P + PP + +
Sbjct: 259 GFYLDGSDTIVCDS----NSTWDPPVPKCLKVLPPSSTKPPALSH 299
>gi|27502423 CD46 antigen, complement regulatory protein isoform 2
precursor [Homo sapiens]
Length = 399
Score = 159 bits (402), Expect = 3e-38
Identities = 99/294 (33%), Positives = 138/294 (46%), Gaps = 17/294 (5%)
Query: 25 GSLLAVVVLLALPVAWGQCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYSGRP--- 81
G LLA +VLL + C P + + IG ++Y+C+ GY P
Sbjct: 18 GLLLAAMVLLLYSFS-DACEEPPTFEAMELIGKPKPY-YEIGERVDYKCKKGYFYIPPLA 75
Query: 82 FSIICLKNSVWTGAKD-RCRRKSCRNPPDPVNGMVHVIKGI-QFGSQIKYSCTKGYRLIG 139
IC +N W D C R++C DP+NG G +FG Q+ + C +GY LIG
Sbjct: 76 THTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIG 135
Query: 140 SSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGS 199
C + G IW + PIC+++ C PP I NG + E F Y VTY C+P +
Sbjct: 136 EEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP-A 194
Query: 200 GGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLN 259
G F L+GE +IYC N +WS AP+C + KC P VENG +S F
Sbjct: 195 PGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-KCRFPVVENGKQISGFGKKFYYK 249
Query: 260 EVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQP----PPDVLHAERT 309
V F C GF + G + C + + W+P +P C +V P PP + H+ T
Sbjct: 250 ATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHSVST 303
Score = 154 bits (389), Expect = 8e-37
Identities = 90/258 (34%), Positives = 120/258 (46%), Gaps = 15/258 (5%)
Query: 1416 FPVGTSLNYECRPGYF---GKMFSISCLENLVWSSVEDN-CRRKSCGPPPEPFNGM-VHI 1470
+ +G ++Y+C+ GYF C N W V D+ C R++C +P NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1471 NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDF 1530
N +FG +++ CNEG+ LIG C + G+ W K PICE + C PPP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1531 YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNK 1590
+ F VTY C P G F L+GE +IYC VWS P C K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAP-GPDPFSLIGESTIYCGDN----SVWSRAAPEC-KVVK 227
Query: 1591 CTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVC 1650
C P VEN ++ G F + F C GF + GS T+ C +N W P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVL 287
Query: 1651 QP----PPEILHGEHTLS 1664
P PP + H T S
Sbjct: 288 PPSSTKPPALSHSVSTSS 305
Score = 151 bits (382), Expect = 5e-36
Identities = 90/256 (35%), Positives = 126/256 (49%), Gaps = 15/256 (5%)
Query: 513 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 567
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 568 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDF 627
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 628 ISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 687
+ E F Y VTY C+P + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDP-APGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 688 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC 747
C P VENG +S F V F C GF + G + C + + W+P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVL 287
Query: 748 QP----PPDVLHAERT 759
P PP + H+ T
Sbjct: 288 PPSSTKPPALSHSVST 303
Score = 149 bits (377), Expect = 2e-35
Identities = 90/258 (34%), Positives = 125/258 (48%), Gaps = 15/258 (5%)
Query: 963 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 1017
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1018 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDF 1077
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1078 ISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 1137
+ E F Y VTY C+ + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCD-PAPGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 1138 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC 1197
C P VENG +S F V F C GF + G + C + + W+P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVL 287
Query: 1198 QP----PPEILHGEHTPS 1211
P PP + H T S
Sbjct: 288 PPSSTKPPALSHSVSTSS 305
Score = 130 bits (327), Expect = 1e-29
Identities = 84/265 (31%), Positives = 121/265 (45%), Gaps = 14/265 (5%)
Query: 740 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 797
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 798 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 855
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 856 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGE 915
++W+ P+CE++ C PP I NG+HT +EVF + AV Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 916 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 975
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 976 EYY-GRPFSITCLDNLVWSSPKDVC 999
+Y +I C N W P C
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 129 bits (323), Expect = 4e-29
Identities = 83/265 (31%), Positives = 120/265 (45%), Gaps = 14/265 (5%)
Query: 290 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 347
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 348 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 405
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 406 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGE 465
++W+ P+CE++ C PP I NG+HT +EVF + V Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 466 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 525
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 526 EYY-GRPFSITCLDNLVWSSPKDVC 549
+Y +I C N W P C
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 122 bits (306), Expect = 4e-27
Identities = 77/265 (29%), Positives = 118/265 (44%), Gaps = 14/265 (5%)
Query: 1647 SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLH--CTPQGDWSPEAP 1704
S C+ PP E + + G+ V Y C+ Y + H C W P +
Sbjct: 32 SDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 1705 RCTVKSCDDFLGQLPHGRVLLPLN--LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALW 1762
+ ++ +G+ + P N + G ++ F+C+EG+ L G +C L G A+W
Sbjct: 92 DACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 1763 NSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIR 1822
+ P+CE++ C PP I NG+HT + Y ++Y+CD P F+LIGES+I
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIY 209
Query: 1823 CTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYL 1882
C N VWS AP C++ C P ++NG I G + T+ + CD G+
Sbjct: 210 CGD----NSVWSRAAPECKV---VKCRF-PVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1883 LVGKGFIFCTDQGIWSQLDHYCKEV 1907
L G I C W C +V
Sbjct: 262 LDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 114 bits (286), Expect = 7e-25
Identities = 79/270 (29%), Positives = 120/270 (44%), Gaps = 21/270 (7%)
Query: 1190 LPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH--CTPQGDWS 1247
L S S C+ PP E + + G+ V Y C+ GY + H C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 1248 PEAPRCAVKSCDDFLGQLPHGRVLFPLN--LQLGAKVSFVCDEGFRLKGSSVSHCVLVGM 1305
P + + ++ +G+ + P N + G ++ F+C+EG+ L G + +C L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
++W+ P+CE + C PP I NG+HT + Y ++Y+CDP P F+LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGE 205
Query: 1366 STIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDF--EFPVGTSLN 1423
STI C N VWS AP C++ C+ FP I+ F +F ++
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV----KCR----FPVVENGKQISGFGKKFYYKATVM 253
Query: 1424 YECRPG-YFGKMFSISCLENLVWSSVEDNC 1452
+EC G Y +I C N W C
Sbjct: 254 FECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 110 bits (274), Expect = 2e-23
Identities = 70/243 (28%), Positives = 115/243 (47%), Gaps = 21/243 (8%)
Query: 1730 QLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTP 1789
++G +V + C +G+ A+H + S C + CP LNG+
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1790 FGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGN-GVWSSPAPRCELSVPAAC 1848
G +G ++ + C+ + LIGE + C + +G+ +WS P CE C
Sbjct: 115 -GTYEFGYQMHFICNEG------YYLIGEEILYC--ELKGSVAIWSGKPPICE---KVLC 162
Query: 1849 PHPPKIQNGHYIGGHVSLYLPGMTISYICDPG-----YLLVGKGFIFCTDQGIWSQLDHY 1903
PPKI+NG + V ++ ++Y CDP + L+G+ I+C D +WS+
Sbjct: 163 TPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPE 222
Query: 1904 CKEVNCSFPLFMNGISKELE-MKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPL 1962
CK V C FP+ NG K++ K ++Y V +C+ G+ L+GS C ++ WDPP+
Sbjct: 223 CKVVKCRFPVVENG--KQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 1963 AKC 1965
KC
Sbjct: 281 PKC 283
Score = 89.7 bits (221), Expect = 3e-17
Identities = 87/324 (26%), Positives = 132/324 (40%), Gaps = 43/324 (13%)
Query: 1066 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1125
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 1126 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 1181
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 1182 --ALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPG-----YDLR 1233
++ W + P C +V C PPP+I +G+HT S + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1234 GAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVL--FPLNLQLGAKVSFVCDEGFR 1291
G ++++C WS AP C V C + +G+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1292 LKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPN---PPAILNGRHT--------GTPSGDI 1340
L GS C S W+ VP C + P+ PPA+ + T + SG
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKCLKVLPPSSTKPPALSHSVSTSSTTKSPASSASGPR 318
Query: 1341 P-YGKEIS-YTCDPHPDRGMTFNL 1362
P Y +S Y P P+ G+ +L
Sbjct: 319 PTYKPPVSNYPGYPKPEEGILDSL 342
Score = 87.8 bits (216), Expect = 1e-16
Identities = 58/237 (24%), Positives = 90/237 (37%), Gaps = 13/237 (5%)
Query: 1022 QVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTN 1081
++G R++Y C G+ I + I N C R C NG + N
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1082 RENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP 1141
+ +G + + CN G + L+GE +YC V IWSG P C PP
Sbjct: 115 G-TYEFGYQMHFICNEG------YYLIGEEILYCELKGS-VAIWSGKPPICEKVLCTPPP 166
Query: 1142 NVENGILVSDNRSLFSLNEVVEFRCQPG-----FVMKGPRRVKCQALNKWEPELPSCSRV 1196
++NG +F + V + C P F + G + C + W P C V
Sbjct: 167 KIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVV 226
Query: 1197 CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1253
P + +G+ F V + C+ G+ L G+ ++ C W P P+C
Sbjct: 227 KCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 85.1 bits (209), Expect = 6e-16
Identities = 64/260 (24%), Positives = 98/260 (37%), Gaps = 19/260 (7%)
Query: 1456 SCGPPPEPFNGMVHINTDTQF---GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTW-DKKA 1511
+C PP F M I + G V+Y C +G+ I P T + N TW
Sbjct: 34 ACEEPPT-FEAMELIGKPKPYYEIGERVDYKCKKGYFYI-PPLATHTICDRNHTWLPVSD 91
Query: 1512 PICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSK 1571
C +C NG N T + G + + C+ G + L+GE +YC K
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGT-YEFGYQMHFICNEG------YYLIGEEILYCELK 144
Query: 1572 DDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPG-----FVMV 1626
V +WS PP C P+++N F + + + C P F ++
Sbjct: 145 GS-VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1627 GSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLR 1686
G T+ C N W P C V P + +G+ F V + C+ + L
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLD 263
Query: 1687 GAASLHCTPQGDWSPEAPRC 1706
G+ ++ C W P P+C
Sbjct: 264 GSDTIVCDSNSTWDPPVPKC 283
Score = 84.7 bits (208), Expect = 8e-16
Identities = 75/285 (26%), Positives = 114/285 (40%), Gaps = 33/285 (11%)
Query: 166 CGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 225
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 226 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 282
+ C P + NG V N + + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPANGT-YEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 283 LNK---WEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG-----YDLR 333
W + P C +V C PPP + + + T + + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 334 GAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVL--FPVNLQLGAKVDFVCDEGFQ 391
G +++ C WS AAP C+V C + NG+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 392 LKGSSASYCVLAGMESLWNSSVPVCEQIFCPS---PPVIPNGRHT 433
L GS C S W+ VP C ++ PS PP + + T
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKCLKVLPPSSTKPPALSHSVST 303
Score = 84.7 bits (208), Expect = 8e-16
Identities = 75/285 (26%), Positives = 115/285 (40%), Gaps = 33/285 (11%)
Query: 616 CGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 675
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 676 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 731
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 732 --ALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG-----YDLR 783
++ W + P C +V C PPP + + + T + + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 784 GAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVL--FPVNLQLGAKVDFVCDEGFQ 841
G +++ C WS AAP C+V C + NG+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 842 LKGSSASYCVLAGMESLWNSSVPVCEQIFCPS---PPVIPNGRHT 883
L GS C S W+ VP C ++ PS PP + + T
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKCLKVLPPSSTKPPALSHSVST 303
Score = 73.2 bits (178), Expect = 2e-12
Identities = 66/262 (25%), Positives = 108/262 (41%), Gaps = 30/262 (11%)
Query: 1140 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP--RRVKCQALNKWEP-ELPSCSR- 1195
PP E L+ + + + E V+++C+ G+ P C + W P +C R
Sbjct: 38 PPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRE 97
Query: 1196 VCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD---WSPEAPR 1252
C + L+G+ P++ + G ++ + C GY L G L+C +G WS + P
Sbjct: 98 TCPYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPI 156
Query: 1253 CAVKSCDDFLGQLPHGRVLFP--LNLQLGAKVSFVCD-----EGFRLKGSSVSHCVLVGM 1305
C C ++ +G+ F + V++ CD + F L G S +C G
Sbjct: 157 CEKVLCTP-PPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC---GD 212
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
S+W+ + P C+ + C P + NG+ Y + + CD F L G
Sbjct: 213 NSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECD------KGFYLDGS 265
Query: 1366 STIRCTSDPHGNGVWSSPAPRC 1387
TI C S N W P P+C
Sbjct: 266 DTIVCDS----NSTWDPPVPKC 283
Score = 68.6 bits (166), Expect = 6e-11
Identities = 67/285 (23%), Positives = 118/285 (41%), Gaps = 33/285 (11%)
Query: 1588 TNKCTAPEVENAIRVPGN-RSFFTLTEIIRFRCQPGFVMV---GSHTVQCQTNGRWGPKL 1643
++ C P A+ + G + ++ + E + ++C+ G+ + +HT+ C N W P
Sbjct: 32 SDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTI-CDRNHTWLPVS 90
Query: 1644 PH-CSR-VCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGD--- 1698
C R C + L+G+ + + G ++ + C Y L G L+C +G
Sbjct: 91 DDACYRETCPYIRDPLNGQ-AVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 1699 WSPEAPRCTVKSCDD--FLGQLPHGRVLLPLNLQLGAKVSFVCD-----EGFRLKGRSAS 1751
WS + P C C + H + + L A V++ CD + F L G S
Sbjct: 150 WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDA-VTYSCDPAPGPDPFSLIGESTI 208
Query: 1752 HCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGM 1811
+C G ++W+ + P C+ + C P + NG+ +GK+ Y +
Sbjct: 209 YC---GDNSVWSRAAPECKVVKC-RFPVVENGKQISG------FGKKFYYKATVMFECDK 258
Query: 1812 TFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQN 1856
F L G +I C S N W P P+C +P + PP + +
Sbjct: 259 GFYLDGSDTIVCDS----NSTWDPPVPKCLKVLPPSSTKPPALSH 299
>gi|187960042 selectin E precursor [Homo sapiens]
Length = 610
Score = 155 bits (391), Expect = 5e-37
Identities = 122/446 (27%), Positives = 182/446 (40%), Gaps = 48/446 (10%)
Query: 1349 TCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPT 1408
+C H + T N C DP +G+ +CE V ++PE +
Sbjct: 147 SCSGHGECVETIN-----NYTCKCDPGFSGL------KCEQIVNCTALESPEHGSLVC-S 194
Query: 1409 IPINDFEFPVGTSLNYECRPGYF-GKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGM 1467
P+ +F + +S + C GY M ++ C+ + WS+ C C P NG
Sbjct: 195 HPLGNFSY--NSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGF 252
Query: 1468 VHINTDT---QFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPT 1524
V + + +T + C EGF L+G+ S C SGN WD + P C+ ++C
Sbjct: 253 VECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGN---WDNEKPTCKAVTCRAVRQ 309
Query: 1525 ISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPR 1584
NG R S T++ E+ F L G + CT++ G W+ P
Sbjct: 310 PQNGSV----RCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQ----GQWTQQIPV 361
Query: 1585 CISTNKCTA---PEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGP 1641
C +CTA PE +P F F C+ GFV+ GS +QC G W
Sbjct: 362 C-EAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDN 420
Query: 1642 KLP-----HCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQ 1696
+ P C V QPP ++ H S F+ +SCE ++L G+ L CT Q
Sbjct: 421 EKPTCEAVRCDAVHQPPKGLVRCAH--SPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQ 478
Query: 1697 GDWSPEAPRCTVKSCDDFLGQLPHGRVLLPLNLQ--LGAKVSFVCDEGFRLKGRSASHCV 1754
G W+ E P C V C +P G++ + + + G F C EG+ L G +A C
Sbjct: 479 GQWTEEVPSCQVVKCSSL--AVP-GKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTC- 534
Query: 1755 LAGMKALWNSSVPVCEQIFCPNPPAI 1780
G W+ +P CE N P +
Sbjct: 535 --GATGHWSGLLPTCEAPTESNIPLV 558
Score = 141 bits (355), Expect = 7e-33
Identities = 109/400 (27%), Positives = 165/400 (41%), Gaps = 44/400 (11%)
Query: 1003 SCKTPPDPVNGMV---HVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPP 1059
+C P +G + H + + S + SC G+ + +C+ SG WS P
Sbjct: 179 NCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGE---WSAPIP 235
Query: 1060 ICQRIPCGLPPTIANGDFIST--NRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTS 1117
C + C ANG F+ N +F + + T+ C G FEL+G S+ CTS
Sbjct: 236 ACNVVECDAVTNPANG-FVECFQNPGSFPWNTTCTFDCEEG------FELMGAQSLQCTS 288
Query: 1118 NDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSL--FSLNEVVEFRCQPGFVMKGP 1175
+ G W P C +NG + + F+ F C+ GF+++GP
Sbjct: 289 S----GNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGP 344
Query: 1176 RRVKCQALNKWEPELPSCSR---VCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDL 1232
+V+C +W ++P C PE + PS +F G +SCE G+ L
Sbjct: 345 AQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVL 404
Query: 1233 RGAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVL---FPL-NLQLGAKVSFVCDE 1288
+G+ L C P G+W E P C C D + Q P G V P+ + +F C+E
Sbjct: 405 KGSKRLQCGPTGEWDNEKPTCEAVRC-DAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEE 463
Query: 1289 GFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISY 1348
GF L GS+ C G W VP C+ + C + + G+ + SG+ +G +
Sbjct: 464 GFELHGSTQLECTSQGQ---WTEEVPSCQVVKCSS--LAVPGKINMSCSGEPVFGTVCKF 518
Query: 1349 TCDPHPDRGMTFNLIGESTIRCTSDPHGNGVWSSPAPRCE 1388
C G T N G + C + H WS P CE
Sbjct: 519 AC----PEGWTLN--GSAARTCGATGH----WSGLLPTCE 548
Score = 135 bits (339), Expect = 5e-31
Identities = 118/450 (26%), Positives = 180/450 (40%), Gaps = 72/450 (16%)
Query: 65 IGTYLNYECR--PGYSGRPFSIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMV---HVIK 119
+ T NY C+ PG+SG I +C P +G + H +
Sbjct: 155 VETINNYTCKCDPGFSGLKCEQIV----------------NCTALESPEHGSLVCSHPLG 198
Query: 120 GIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFIS 179
+ S SC +GY + C+ SG+ W P C+ + C NG F+
Sbjct: 199 NFSYNSSCSISCDRGYLPSSMETMQCMSSGE---WSAPIPACNVVECDAVTNPANG-FVE 254
Query: 180 T--NRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 237
N +F + + T+ C G FEL+G S+ CTS+ G W P C
Sbjct: 255 CFQNPGSFPWNTTCTFDCEEG------FELMGAQSLQCTSS----GNWDNEKPTCKAVTC 304
Query: 238 CTPPNVENGILVSDNRSL--FSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSR 295
+NG + + F+ F C+ GF+++GP +V+C +W ++P C
Sbjct: 305 RAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEA 364
Query: 296 ---VCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPT 352
P+ + +F G +SCE G+ L+G+ ++C P G+W PT
Sbjct: 365 FQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPT 424
Query: 353 CEVKSCDDFMGQLLNGRVL---FPV-NLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESL 408
CE C D + Q G V P+ + F C+EGF+L GS+ C G
Sbjct: 425 CEAVRC-DAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQ--- 480
Query: 409 WNSSVPVCEQIFCPS--PPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGES 466
W VP C+ + C S P N +G+P+ FG + C P+ T L G +
Sbjct: 481 WTEEVPSCQVVKCSSLAVPGKINMSCSGEPV----FGTVCKFAC---PEGWT---LNGSA 530
Query: 467 TIRCTSDPQGNGVWSSPAPRCGILGHCQAP 496
C + G WS G+L C+AP
Sbjct: 531 ARTCGA----TGHWS------GLLPTCEAP 550
Score = 133 bits (335), Expect = 2e-30
Identities = 101/398 (25%), Positives = 156/398 (39%), Gaps = 31/398 (7%)
Query: 1609 FTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV-CQPPPEILHG-EHTLSHQ 1666
F+ C G++ T+QC ++G W +P C+ V C +G +
Sbjct: 200 FSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNP 259
Query: 1667 DNFSPGQEVFYSCEPSYDLRGAASLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLP 1726
+F + CE ++L GA SL CT G+W E P C +C + Q +G V
Sbjct: 260 GSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRA-VRQPQNGSVRCS 318
Query: 1727 LN----LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILN 1782
+ + +F C+EGF L+G + C G W +PVCE C
Sbjct: 319 HSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQ---WTQQIPVCEAFQCTALSNPER 375
Query: 1783 GRHTGTPF--GDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRC 1840
G P G YG ++C+ F L G ++C G W + P C
Sbjct: 376 GYMNCLPSASGSFRYGSSCEFSCE------QGFVLKGSKRLQCGP----TGEWDNEKPTC 425
Query: 1841 ELSVPAACPHPPK--IQNGHYIGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWS 1898
E A PPK ++ H + + + ++ C+ G+ L G + CT QG W+
Sbjct: 426 EAVRCDAVHQPPKGLVRCAH---SPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWT 482
Query: 1899 QLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRW 1958
+ C+ V CS I+ + V +G C +G+TL GS C A W
Sbjct: 483 EEVPSCQVVKCSSLAVPGKINMSCSGEPV--FGTVCKFACPEGWTLNGSAARTCGATGHW 540
Query: 1959 DPPLAKCTSRTHD--ALIVGTLSGTIFFILLIIFLSWI 1994
L C + T L+ G + + + L FL W+
Sbjct: 541 SGLLPTCEAPTESNIPLVAGLSAAGLSLLTLAPFLLWL 578
Score = 132 bits (331), Expect = 5e-30
Identities = 110/410 (26%), Positives = 169/410 (41%), Gaps = 54/410 (13%)
Query: 553 SCKTPPDPVNGMV---HVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPP 609
+C P +G + H + + S + SC G+ + +C+ SG WS P
Sbjct: 179 NCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGE---WSAPIP 235
Query: 610 ICQRIPCGLPPTIANGDFIST--NRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTS 667
C + C ANG F+ N +F + + T+ C G FEL+G S+ CTS
Sbjct: 236 ACNVVECDAVTNPANG-FVECFQNPGSFPWNTTCTFDCEEG------FELMGAQSLQCTS 288
Query: 668 NDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSL--FSLNEVVEFRCQPGFVMKGP 725
+ G W P C +NG + + F+ F C+ GF+++GP
Sbjct: 289 S----GNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGP 344
Query: 726 RRVKCQALNKWEPELPSCSR---VCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDL 782
+V+C +W ++P C P+ + +F G +SCE G+ L
Sbjct: 345 AQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVL 404
Query: 783 RGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVL---FPV-NLQLGAKVDFVCDE 838
+G+ ++C P G+W PTCE C D + Q G V P+ + F C+E
Sbjct: 405 KGSKRLQCGPTGEWDNEKPTCEAVRC-DAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEE 463
Query: 839 GFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPS--PPVIPNGRHTGKPLEVFPFGKAV 896
GF+L GS+ C G W VP C+ + C S P N +G+P+ FG
Sbjct: 464 GFELHGSTQLECTSQGQ---WTEEVPSCQVVKCSSLAVPGKINMSCSGEPV----FGTVC 516
Query: 897 NYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAP 946
+ C P+ T L G + C + G WS G+L C+AP
Sbjct: 517 KFAC---PEGWT---LNGSAARTCGA----TGHWS------GLLPTCEAP 550
Score = 118 bits (296), Expect = 5e-26
Identities = 114/441 (25%), Positives = 166/441 (37%), Gaps = 58/441 (13%)
Query: 265 RCQPGFV-MKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVF 323
+C PGF +K + V C AL E S VC P NFS
Sbjct: 164 KCDPGFSGLKCEQIVNCTALESPEHG----SLVCSHP------------LGNFSYNSSCS 207
Query: 324 YSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLF---PVNLQLGA 380
SC+ GY +M+C G+WS P C V CD NG V P +
Sbjct: 208 ISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPA-NGFVECFQNPGSFPWNT 266
Query: 381 KVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNG--RHTGKPLE 438
F C+EGF+L G+ + C +G W++ P C+ + C + NG R + P
Sbjct: 267 TCTFDCEEGFELMGAQSLQCTSSGN---WDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAG 323
Query: 439 VFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDH 498
F F + N+TC+ F L G + + CT+ G W+ P C C A +
Sbjct: 324 EFTFKSSCNFTCEE------GFMLQGPAQVECTTQ----GQWTQQIPVCEAF-QCTALSN 372
Query: 499 FLFAKLKTQTNAS-DFPIGTSLKYECRPEYYGRPFS-ITCLDNLVWSSPKDVCKRKSCKT 556
+ +AS F G+S ++ C + + + C W + K C+ C
Sbjct: 373 PERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDA 432
Query: 557 PPDPVNGMVHV----ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQ 612
P G+V I + S +SC G L G + EC G W+ + P CQ
Sbjct: 433 VHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQ---WTEEVPSCQ 489
Query: 613 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQV 672
+ C + + F G+V + C G + L G + C +
Sbjct: 490 VVKCSSLAVPGKINMSCSGEPVF--GTVCKFACPEG------WTLNGSAARTCGAT---- 537
Query: 673 GIWSGPAPQCIIPNKCTPPNV 693
G WSG P C P + P V
Sbjct: 538 GHWSGLLPTCEAPTESNIPLV 558
Score = 117 bits (294), Expect = 9e-26
Identities = 114/441 (25%), Positives = 166/441 (37%), Gaps = 58/441 (13%)
Query: 715 RCQPGFV-MKGPRRVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVF 773
+C PGF +K + V C AL E S VC P NFS
Sbjct: 164 KCDPGFSGLKCEQIVNCTALESPEHG----SLVCSHP------------LGNFSYNSSCS 207
Query: 774 YSCEPGYDLRGAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVLF---PVNLQLGA 830
SC+ GY +M+C G+WS P C V CD NG V P +
Sbjct: 208 ISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPA-NGFVECFQNPGSFPWNT 266
Query: 831 KVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNG--RHTGKPLE 888
F C+EGF+L G+ + C +G W++ P C+ + C + NG R + P
Sbjct: 267 TCTFDCEEGFELMGAQSLQCTSSGN---WDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAG 323
Query: 889 VFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQAPDH 948
F F + N+TC+ F L G + + CT+ G W+ P C C A +
Sbjct: 324 EFTFKSSCNFTCEE------GFMLQGPAQVECTTQ----GQWTQQIPVCEAF-QCTALSN 372
Query: 949 FLFAKLKTQTNAS-DFPIGTSLKYECRPEYYGRPFS-ITCLDNLVWSSPKDVCKRKSCKT 1006
+ +AS F G+S ++ C + + + C W + K C+ C
Sbjct: 373 PERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDA 432
Query: 1007 PPDPVNGMVHV----ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQ 1062
P G+V I + S +SC G L G + EC G W+ + P CQ
Sbjct: 433 VHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQ---WTEEVPSCQ 489
Query: 1063 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQV 1122
+ C + + F G+V + C G + L G + C +
Sbjct: 490 VVKCSSLAVPGKINMSCSGEPVF--GTVCKFACPEG------WTLNGSAARTCGAT---- 537
Query: 1123 GIWSGPAPQCIIPNKCTPPNV 1143
G WSG P C P + P V
Sbjct: 538 GHWSGLLPTCEAPTESNIPLV 558
Score = 117 bits (293), Expect = 1e-25
Identities = 98/386 (25%), Positives = 154/386 (39%), Gaps = 50/386 (12%)
Query: 436 PLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQA 495
PL F + + + +CD RG + T++C S +G WS+P P C ++ C A
Sbjct: 196 PLGNFSYNSSCSISCD----RG--YLPSSMETMQCMS----SGEWSAPIPACNVV-ECDA 244
Query: 496 PDHFLFAKLKTQTNASDFPIGTSLKYECRP--EYYGRPFSITCLDNLVWSSPKDVCKRKS 553
+ ++ N FP T+ ++C E G S+ C + W + K CK +
Sbjct: 245 VTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQ-SLQCTSSGNWDNEKPTCKAVT 303
Query: 554 CKTPPDPVNGMVHV----ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPP 609
C+ P NG V + S N++C G L G + EC G W+ + P
Sbjct: 304 CRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQG---QWTQQIP 360
Query: 610 ICQRIPCGLPPTIANG--DFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTS 667
+C+ C G + + + +F YGS + C G F L G + C
Sbjct: 361 VCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQG------FVLKGSKRLQC-- 412
Query: 668 NDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSL--FSLNEVVEFRCQPGFVMKGP 725
G W P C G++ + + F+ F C+ GF + G
Sbjct: 413 --GPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGS 470
Query: 726 RRVKCQALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFS-PGQEVF-----YSCEP 778
+++C + +W E+PSC V C + K N S G+ VF ++C
Sbjct: 471 TQLECTSQGQWTEEVPSCQVVKC--------SSLAVPGKINMSCSGEPVFGTVCKFACPE 522
Query: 779 GYDLRGAASMRCTPQGDWSPAAPTCE 804
G+ L G+A+ C G WS PTCE
Sbjct: 523 GWTLNGSAARTCGATGHWSGLLPTCE 548
Score = 111 bits (278), Expect = 6e-24
Identities = 92/378 (24%), Positives = 150/378 (39%), Gaps = 36/378 (9%)
Query: 886 PLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGILGHCQA 945
PL F + + + +CD RG + T++C S +G WS+P P C ++ C A
Sbjct: 196 PLGNFSYNSSCSISCD----RG--YLPSSMETMQCMS----SGEWSAPIPACNVV-ECDA 244
Query: 946 PDHFLFAKLKTQTNASDFPIGTSLKYECRP--EYYGRPFSITCLDNLVWSSPKDVCKRKS 1003
+ ++ N FP T+ ++C E G S+ C + W + K CK +
Sbjct: 245 VTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQ-SLQCTSSGNWDNEKPTCKAVT 303
Query: 1004 CKTPPDPVNGMVHV----ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPP 1059
C+ P NG V + S N++C G L G + EC G W+ + P
Sbjct: 304 CRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQG---QWTQQIP 360
Query: 1060 ICQRIPCGLPPTIANG--DFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTS 1117
+C+ C G + + + +F YGS + C G F L G + C
Sbjct: 361 VCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQG------FVLKGSKRLQC-- 412
Query: 1118 NDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSL--FSLNEVVEFRCQPGFVMKGP 1175
G W P C G++ + + F+ F C+ GF + G
Sbjct: 413 --GPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGS 470
Query: 1176 RRVKCQALNKWEPELPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGA 1235
+++C + +W E+PSC +V + + G+ S G ++C G+ L G+
Sbjct: 471 TQLECTSQGQWTEEVPSC-QVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGS 529
Query: 1236 ASLHCTPQGDWSPEAPRC 1253
A+ C G WS P C
Sbjct: 530 AARTCGATGHWSGLLPTC 547
Score = 82.4 bits (202), Expect = 4e-15
Identities = 63/255 (24%), Positives = 99/255 (38%), Gaps = 29/255 (11%)
Query: 1728 NLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNG--RH 1785
N + S CD G+ C+ +G W++ +P C + C NG
Sbjct: 199 NFSYNSSCSISCDRGYLPSSMETMQCMSSGE---WSAPIPACNVVECDAVTNPANGFVEC 255
Query: 1786 TGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVP 1845
P G P+ ++ C+ F L+G S++CTS +G W + P C+
Sbjct: 256 FQNP-GSFPWNTTCTFDCEEG------FELMGAQSLQCTS----SGNWDNEKPTCKAVTC 304
Query: 1846 AACPHPPKIQNGHYIGGH--VSLYLPGMTISYICDPGYLLVGKGFIFCTDQGIWSQLDHY 1903
A P QNG H + + ++ C+ G++L G + CT QG W+Q
Sbjct: 305 RAVRQP---QNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPV 361
Query: 1904 CKEVNCSFPL-----FMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRW 1958
C+ C+ +MN + + YG CE G+ L+GS QC W
Sbjct: 362 CEAFQCTALSNPERGYMNCLP---SASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEW 418
Query: 1959 DPPLAKCTSRTHDAL 1973
D C + DA+
Sbjct: 419 DNEKPTCEAVRCDAV 433
Score = 50.4 bits (119), Expect = 2e-05
Identities = 47/189 (24%), Positives = 69/189 (36%), Gaps = 26/189 (13%)
Query: 63 FPIGTYLNYECRPGYSGRPFSII-CLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHV---- 117
F G+ + C G+ + + C W K C C P G+V
Sbjct: 388 FRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSP 447
Query: 118 IKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCG---LPPTITN 174
I + S +SC +G+ L GS+ C G W E P C + C +P I
Sbjct: 448 IGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQ---WTEEVPSCQVVKCSSLAVPGKIN- 503
Query: 175 GDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCII 234
+S + E +G+V + C G + L G + C + G WSG P C
Sbjct: 504 ---MSCSGEPV-FGTVCKFACPEG------WTLNGSAARTCGAT----GHWSGLLPTCEA 549
Query: 235 PNKCTPPNV 243
P + P V
Sbjct: 550 PTESNIPLV 558
>gi|27502421 CD46 antigen, complement regulatory protein isoform 13
precursor [Homo sapiens]
Length = 373
Score = 154 bits (390), Expect = 6e-37
Identities = 94/277 (33%), Positives = 131/277 (47%), Gaps = 13/277 (4%)
Query: 25 GSLLAVVVLLALPVAWGQCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYSGRP--- 81
G LLA +VLL + C P + + IG ++Y+C+ GY P
Sbjct: 18 GLLLAAMVLLLYSFS-DACEEPPTFEAMELIGKPKPY-YEIGERVDYKCKKGYFYIPPLA 75
Query: 82 FSIICLKNSVWTGAKD-RCRRKSCRNPPDPVNGMVHVIKGI-QFGSQIKYSCTKGYRLIG 139
IC +N W D C R++C DP+NG G +FG Q+ + C +GY LIG
Sbjct: 76 THTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIG 135
Query: 140 SSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGS 199
C + G IW + PIC+++ C PP I NG + E F Y VTY C+P +
Sbjct: 136 EEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP-A 194
Query: 200 GGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLN 259
G F L+GE +IYC N +WS AP+C + KC P VENG +S F
Sbjct: 195 PGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-KCRFPVVENGKQISGFGKKFYYK 249
Query: 260 EVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 296
V F C GF + G + C + + W+P +P C +V
Sbjct: 250 ATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 148 bits (374), Expect = 5e-35
Identities = 84/239 (35%), Positives = 113/239 (47%), Gaps = 11/239 (4%)
Query: 1416 FPVGTSLNYECRPGYF---GKMFSISCLENLVWSSVEDN-CRRKSCGPPPEPFNGM-VHI 1470
+ +G ++Y+C+ GYF C N W V D+ C R++C +P NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1471 NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDF 1530
N +FG +++ CNEG+ LIG C + G+ W K PICE + C PPP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1531 YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNK 1590
+ F VTY C P G F L+GE +IYC VWS P C K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAP-GPDPFSLIGESTIYCGDN----SVWSRAAPEC-KVVK 227
Query: 1591 CTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV 1649
C P VEN ++ G F + F C GF + GS T+ C +N W P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 147 bits (370), Expect = 1e-34
Identities = 85/239 (35%), Positives = 119/239 (49%), Gaps = 11/239 (4%)
Query: 513 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 567
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 568 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDF 627
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 628 ISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 687
+ E F Y VTY C+P + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDP-APGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 688 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 746
C P VENG +S F V F C GF + G + C + + W+P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 143 bits (361), Expect = 1e-33
Identities = 84/239 (35%), Positives = 118/239 (49%), Gaps = 11/239 (4%)
Query: 963 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 1017
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1018 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDF 1077
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1078 ISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 1137
+ E F Y VTY C+ + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCD-PAPGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 1138 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 1196
C P VENG +S F V F C GF + G + C + + W+P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 132 bits (331), Expect = 5e-30
Identities = 88/283 (31%), Positives = 128/283 (45%), Gaps = 18/283 (6%)
Query: 740 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 797
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 798 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 855
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 856 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGE 915
++W+ P+CE++ C PP I NG+HT +EVF + AV Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 916 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 975
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 976 EYY-GRPFSITCLDNLVWSSPKDVCKRKS----CKTPPDPVNG 1013
+Y +I C N W P C + S K+P +G
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSASG 301
Score = 130 bits (327), Expect = 1e-29
Identities = 87/283 (30%), Positives = 127/283 (44%), Gaps = 18/283 (6%)
Query: 290 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 347
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 348 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 405
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 406 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGE 465
++W+ P+CE++ C PP I NG+HT +EVF + V Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 466 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 525
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 526 EYY-GRPFSITCLDNLVWSSPKDVCKRKS----CKTPPDPVNG 563
+Y +I C N W P C + S K+P +G
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSASG 301
Score = 124 bits (310), Expect = 1e-27
Identities = 78/268 (29%), Positives = 120/268 (44%), Gaps = 14/268 (5%)
Query: 1647 SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLH--CTPQGDWSPEAP 1704
S C+ PP E + + G+ V Y C+ Y + H C W P +
Sbjct: 32 SDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 1705 RCTVKSCDDFLGQLPHGRVLLPLN--LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALW 1762
+ ++ +G+ + P N + G ++ F+C+EG+ L G +C L G A+W
Sbjct: 92 DACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 1763 NSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIR 1822
+ P+CE++ C PP I NG+HT + Y ++Y+CD P F+LIGES+I
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIY 209
Query: 1823 CTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYL 1882
C N VWS AP C++ C P ++NG I G + T+ + CD G+
Sbjct: 210 CGD----NSVWSRAAPECKV---VKCRF-PVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1883 LVGKGFIFCTDQGIWSQLDHYCKEVNCS 1910
L G I C W C +V+ S
Sbjct: 262 LDGSDTIVCDSNSTWDPPVPKCLKVSTS 289
Score = 115 bits (288), Expect = 4e-25
Identities = 80/274 (29%), Positives = 122/274 (44%), Gaps = 21/274 (7%)
Query: 1190 LPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH--CTPQGDWS 1247
L S S C+ PP E + + G+ V Y C+ GY + H C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 1248 PEAPRCAVKSCDDFLGQLPHGRVLFPLN--LQLGAKVSFVCDEGFRLKGSSVSHCVLVGM 1305
P + + ++ +G+ + P N + G ++ F+C+EG+ L G + +C L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
++W+ P+CE + C PP I NG+HT + Y ++Y+CDP P F+LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGE 205
Query: 1366 STIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDF--EFPVGTSLN 1423
STI C N VWS AP C++ C+ FP I+ F +F ++
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV----KCR----FPVVENGKQISGFGKKFYYKATVM 253
Query: 1424 YECRPG-YFGKMFSISCLENLVWSSVEDNCRRKS 1456
+EC G Y +I C N W C + S
Sbjct: 254 FECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVS 287
Score = 110 bits (274), Expect = 2e-23
Identities = 70/243 (28%), Positives = 115/243 (47%), Gaps = 21/243 (8%)
Query: 1730 QLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTP 1789
++G +V + C +G+ A+H + S C + CP LNG+
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1790 FGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGN-GVWSSPAPRCELSVPAAC 1848
G +G ++ + C+ + LIGE + C + +G+ +WS P CE C
Sbjct: 115 -GTYEFGYQMHFICNEG------YYLIGEEILYC--ELKGSVAIWSGKPPICE---KVLC 162
Query: 1849 PHPPKIQNGHYIGGHVSLYLPGMTISYICDPG-----YLLVGKGFIFCTDQGIWSQLDHY 1903
PPKI+NG + V ++ ++Y CDP + L+G+ I+C D +WS+
Sbjct: 163 TPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPE 222
Query: 1904 CKEVNCSFPLFMNGISKELE-MKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPL 1962
CK V C FP+ NG K++ K ++Y V +C+ G+ L+GS C ++ WDPP+
Sbjct: 223 CKVVKCRFPVVENG--KQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 1963 AKC 1965
KC
Sbjct: 281 PKC 283
Score = 87.8 bits (216), Expect = 1e-16
Identities = 58/237 (24%), Positives = 90/237 (37%), Gaps = 13/237 (5%)
Query: 1022 QVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTN 1081
++G R++Y C G+ I + I N C R C NG + N
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1082 RENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP 1141
+ +G + + CN G + L+GE +YC V IWSG P C PP
Sbjct: 115 G-TYEFGYQMHFICNEG------YYLIGEEILYCELKGS-VAIWSGKPPICEKVLCTPPP 166
Query: 1142 NVENGILVSDNRSLFSLNEVVEFRCQPG-----FVMKGPRRVKCQALNKWEPELPSCSRV 1196
++NG +F + V + C P F + G + C + W P C V
Sbjct: 167 KIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVV 226
Query: 1197 CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1253
P + +G+ F V + C+ G+ L G+ ++ C W P P+C
Sbjct: 227 KCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 85.1 bits (209), Expect = 6e-16
Identities = 64/260 (24%), Positives = 98/260 (37%), Gaps = 19/260 (7%)
Query: 1456 SCGPPPEPFNGMVHINTDTQF---GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTW-DKKA 1511
+C PP F M I + G V+Y C +G+ I P T + N TW
Sbjct: 34 ACEEPPT-FEAMELIGKPKPYYEIGERVDYKCKKGYFYI-PPLATHTICDRNHTWLPVSD 91
Query: 1512 PICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSK 1571
C +C NG N T + G + + C+ G + L+GE +YC K
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGT-YEFGYQMHFICNEG------YYLIGEEILYCELK 144
Query: 1572 DDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPG-----FVMV 1626
V +WS PP C P+++N F + + + C P F ++
Sbjct: 145 GS-VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1627 GSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLR 1686
G T+ C N W P C V P + +G+ F V + C+ + L
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLD 263
Query: 1687 GAASLHCTPQGDWSPEAPRC 1706
G+ ++ C W P P+C
Sbjct: 264 GSDTIVCDSNSTWDPPVPKC 283
Score = 84.7 bits (208), Expect = 8e-16
Identities = 72/265 (27%), Positives = 108/265 (40%), Gaps = 30/265 (11%)
Query: 1066 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1125
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 1126 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 1181
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 1182 --ALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPG-----YDLR 1233
++ W + P C +V C PPP+I +G+HT S + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1234 GAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVL--FPLNLQLGAKVSFVCDEGFR 1291
G ++++C WS AP C V C + +G+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1292 LKGSSVSHCVLVGMRSLWNNSVPVC 1316
L GS C S W+ VP C
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKC 283
Score = 84.3 bits (207), Expect = 1e-15
Identities = 79/306 (25%), Positives = 119/306 (38%), Gaps = 32/306 (10%)
Query: 616 CGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 675
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 676 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 731
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 732 --ALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG-----YDLR 783
++ W + P C +V C PPP + + + T + + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 784 GAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVL--FPVNLQLGAKVDFVCDEGFQ 841
G +++ C WS AAP C+V C + NG+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 842 LKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCD 901
L GS C S W+ VP C ++ S P +G P NY
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKCLKVSTSSTTKSPASSASGPRPTYKP--PVSNYPGY 316
Query: 902 PHPDRG 907
P P+ G
Sbjct: 317 PKPEEG 322
Score = 74.3 bits (181), Expect = 1e-12
Identities = 77/305 (25%), Positives = 125/305 (40%), Gaps = 40/305 (13%)
Query: 1140 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP--RRVKCQALNKWEP-ELPSCSR- 1195
PP E L+ + + + E V+++C+ G+ P C + W P +C R
Sbjct: 38 PPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRE 97
Query: 1196 VCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD---WSPEAPR 1252
C + L+G+ P++ + G ++ + C GY L G L+C +G WS + P
Sbjct: 98 TCPYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPI 156
Query: 1253 CAVKSCDDFLGQLPHGRVLFP--LNLQLGAKVSFVCD-----EGFRLKGSSVSHCVLVGM 1305
C C ++ +G+ F + V++ CD + F L G S +C G
Sbjct: 157 CEKVLCTP-PPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC---GD 212
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
S+W+ + P C+ + C P + NG+ Y + + CD F L G
Sbjct: 213 NSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECD------KGFYLDGS 265
Query: 1366 STIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYE 1425
TI C S N W P P+C + K+P +S + P ++ PV NY
Sbjct: 266 DTIVCDS----NSTWDPPVPKCLKVSTSSTTKSPA----SSASGPRPTYKPPVS---NY- 313
Query: 1426 CRPGY 1430
PGY
Sbjct: 314 --PGY 316
Score = 63.9 bits (154), Expect = 2e-09
Identities = 62/251 (24%), Positives = 100/251 (39%), Gaps = 27/251 (10%)
Query: 1277 QLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTP 1336
++G +V + C +G+ +H + + S C CP LNG+
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA- 113
Query: 1337 SGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGN-GVWSSPAPRCELSVRAGH 1395
+G +G ++ + C+ + LIGE + C + G+ +WS P CE +
Sbjct: 114 NGTYEFGYQMHFICNEG------YYLIGEEILYC--ELKGSVAIWSGKPPICEKVL---- 161
Query: 1396 CKTPEQFPFASPTIP-INDFEFPVGTSLNYECRPGYFGKMFS------ISCLENLVWSSV 1448
C P + T + FE+ ++ Y C P FS I C +N VWS
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRA 219
Query: 1449 EDNCRRKSCG-PPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTW 1507
C+ C P E + + +TV + C++GF L GS + C +N TW
Sbjct: 220 APECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVC---DSNSTW 276
Query: 1508 DKKAPICEIIS 1518
D P C +S
Sbjct: 277 DPPVPKCLKVS 287
>gi|27502417 CD46 antigen, complement regulatory protein isoform 10
precursor [Homo sapiens]
Length = 370
Score = 154 bits (390), Expect = 6e-37
Identities = 94/277 (33%), Positives = 131/277 (47%), Gaps = 13/277 (4%)
Query: 25 GSLLAVVVLLALPVAWGQCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYSGRP--- 81
G LLA +VLL + C P + + IG ++Y+C+ GY P
Sbjct: 18 GLLLAAMVLLLYSFS-DACEEPPTFEAMELIGKPKPY-YEIGERVDYKCKKGYFYIPPLA 75
Query: 82 FSIICLKNSVWTGAKD-RCRRKSCRNPPDPVNGMVHVIKGI-QFGSQIKYSCTKGYRLIG 139
IC +N W D C R++C DP+NG G +FG Q+ + C +GY LIG
Sbjct: 76 THTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIG 135
Query: 140 SSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGS 199
C + G IW + PIC+++ C PP I NG + E F Y VTY C+P +
Sbjct: 136 EEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP-A 194
Query: 200 GGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLN 259
G F L+GE +IYC N +WS AP+C + KC P VENG +S F
Sbjct: 195 PGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-KCRFPVVENGKQISGFGKKFYYK 249
Query: 260 EVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 296
V F C GF + G + C + + W+P +P C +V
Sbjct: 250 ATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 148 bits (374), Expect = 5e-35
Identities = 84/239 (35%), Positives = 113/239 (47%), Gaps = 11/239 (4%)
Query: 1416 FPVGTSLNYECRPGYF---GKMFSISCLENLVWSSVEDN-CRRKSCGPPPEPFNGM-VHI 1470
+ +G ++Y+C+ GYF C N W V D+ C R++C +P NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1471 NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDF 1530
N +FG +++ CNEG+ LIG C + G+ W K PICE + C PPP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1531 YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNK 1590
+ F VTY C P G F L+GE +IYC VWS P C K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAP-GPDPFSLIGESTIYCGDN----SVWSRAAPEC-KVVK 227
Query: 1591 CTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV 1649
C P VEN ++ G F + F C GF + GS T+ C +N W P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 147 bits (370), Expect = 1e-34
Identities = 85/239 (35%), Positives = 119/239 (49%), Gaps = 11/239 (4%)
Query: 513 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 567
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 568 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDF 627
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 628 ISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 687
+ E F Y VTY C+P + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDP-APGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 688 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 746
C P VENG +S F V F C GF + G + C + + W+P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 143 bits (361), Expect = 1e-33
Identities = 84/239 (35%), Positives = 118/239 (49%), Gaps = 11/239 (4%)
Query: 963 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 1017
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1018 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDF 1077
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1078 ISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 1137
+ E F Y VTY C+ + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCD-PAPGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 1138 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 1196
C P VENG +S F V F C GF + G + C + + W+P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 132 bits (331), Expect = 5e-30
Identities = 88/283 (31%), Positives = 128/283 (45%), Gaps = 18/283 (6%)
Query: 740 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 797
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 798 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 855
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 856 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGE 915
++W+ P+CE++ C PP I NG+HT +EVF + AV Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 916 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 975
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 976 EYY-GRPFSITCLDNLVWSSPKDVCKRKS----CKTPPDPVNG 1013
+Y +I C N W P C + S K+P +G
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSASG 301
Score = 130 bits (327), Expect = 1e-29
Identities = 87/283 (30%), Positives = 127/283 (44%), Gaps = 18/283 (6%)
Query: 290 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 347
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 348 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 405
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 406 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGE 465
++W+ P+CE++ C PP I NG+HT +EVF + V Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 466 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 525
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 526 EYY-GRPFSITCLDNLVWSSPKDVCKRKS----CKTPPDPVNG 563
+Y +I C N W P C + S K+P +G
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSASG 301
Score = 124 bits (310), Expect = 1e-27
Identities = 78/268 (29%), Positives = 120/268 (44%), Gaps = 14/268 (5%)
Query: 1647 SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLH--CTPQGDWSPEAP 1704
S C+ PP E + + G+ V Y C+ Y + H C W P +
Sbjct: 32 SDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 1705 RCTVKSCDDFLGQLPHGRVLLPLN--LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALW 1762
+ ++ +G+ + P N + G ++ F+C+EG+ L G +C L G A+W
Sbjct: 92 DACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 1763 NSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIR 1822
+ P+CE++ C PP I NG+HT + Y ++Y+CD P F+LIGES+I
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIY 209
Query: 1823 CTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYL 1882
C N VWS AP C++ C P ++NG I G + T+ + CD G+
Sbjct: 210 CGD----NSVWSRAAPECKV---VKCRF-PVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1883 LVGKGFIFCTDQGIWSQLDHYCKEVNCS 1910
L G I C W C +V+ S
Sbjct: 262 LDGSDTIVCDSNSTWDPPVPKCLKVSTS 289
Score = 115 bits (288), Expect = 4e-25
Identities = 80/274 (29%), Positives = 122/274 (44%), Gaps = 21/274 (7%)
Query: 1190 LPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH--CTPQGDWS 1247
L S S C+ PP E + + G+ V Y C+ GY + H C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 1248 PEAPRCAVKSCDDFLGQLPHGRVLFPLN--LQLGAKVSFVCDEGFRLKGSSVSHCVLVGM 1305
P + + ++ +G+ + P N + G ++ F+C+EG+ L G + +C L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
++W+ P+CE + C PP I NG+HT + Y ++Y+CDP P F+LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGE 205
Query: 1366 STIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDF--EFPVGTSLN 1423
STI C N VWS AP C++ C+ FP I+ F +F ++
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV----KCR----FPVVENGKQISGFGKKFYYKATVM 253
Query: 1424 YECRPG-YFGKMFSISCLENLVWSSVEDNCRRKS 1456
+EC G Y +I C N W C + S
Sbjct: 254 FECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVS 287
Score = 110 bits (274), Expect = 2e-23
Identities = 70/243 (28%), Positives = 115/243 (47%), Gaps = 21/243 (8%)
Query: 1730 QLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTP 1789
++G +V + C +G+ A+H + S C + CP LNG+
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1790 FGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGN-GVWSSPAPRCELSVPAAC 1848
G +G ++ + C+ + LIGE + C + +G+ +WS P CE C
Sbjct: 115 -GTYEFGYQMHFICNEG------YYLIGEEILYC--ELKGSVAIWSGKPPICE---KVLC 162
Query: 1849 PHPPKIQNGHYIGGHVSLYLPGMTISYICDPG-----YLLVGKGFIFCTDQGIWSQLDHY 1903
PPKI+NG + V ++ ++Y CDP + L+G+ I+C D +WS+
Sbjct: 163 TPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPE 222
Query: 1904 CKEVNCSFPLFMNGISKELE-MKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPL 1962
CK V C FP+ NG K++ K ++Y V +C+ G+ L+GS C ++ WDPP+
Sbjct: 223 CKVVKCRFPVVENG--KQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 1963 AKC 1965
KC
Sbjct: 281 PKC 283
Score = 87.8 bits (216), Expect = 1e-16
Identities = 58/237 (24%), Positives = 90/237 (37%), Gaps = 13/237 (5%)
Query: 1022 QVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTN 1081
++G R++Y C G+ I + I N C R C NG + N
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1082 RENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP 1141
+ +G + + CN G + L+GE +YC V IWSG P C PP
Sbjct: 115 G-TYEFGYQMHFICNEG------YYLIGEEILYCELKGS-VAIWSGKPPICEKVLCTPPP 166
Query: 1142 NVENGILVSDNRSLFSLNEVVEFRCQPG-----FVMKGPRRVKCQALNKWEPELPSCSRV 1196
++NG +F + V + C P F + G + C + W P C V
Sbjct: 167 KIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVV 226
Query: 1197 CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1253
P + +G+ F V + C+ G+ L G+ ++ C W P P+C
Sbjct: 227 KCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 85.1 bits (209), Expect = 6e-16
Identities = 64/260 (24%), Positives = 98/260 (37%), Gaps = 19/260 (7%)
Query: 1456 SCGPPPEPFNGMVHINTDTQF---GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTW-DKKA 1511
+C PP F M I + G V+Y C +G+ I P T + N TW
Sbjct: 34 ACEEPPT-FEAMELIGKPKPYYEIGERVDYKCKKGYFYI-PPLATHTICDRNHTWLPVSD 91
Query: 1512 PICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSK 1571
C +C NG N T + G + + C+ G + L+GE +YC K
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGT-YEFGYQMHFICNEG------YYLIGEEILYCELK 144
Query: 1572 DDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPG-----FVMV 1626
V +WS PP C P+++N F + + + C P F ++
Sbjct: 145 GS-VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1627 GSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLR 1686
G T+ C N W P C V P + +G+ F V + C+ + L
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLD 263
Query: 1687 GAASLHCTPQGDWSPEAPRC 1706
G+ ++ C W P P+C
Sbjct: 264 GSDTIVCDSNSTWDPPVPKC 283
Score = 84.7 bits (208), Expect = 8e-16
Identities = 72/265 (27%), Positives = 108/265 (40%), Gaps = 30/265 (11%)
Query: 1066 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1125
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 1126 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 1181
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 1182 --ALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPG-----YDLR 1233
++ W + P C +V C PPP+I +G+HT S + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1234 GAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVL--FPLNLQLGAKVSFVCDEGFR 1291
G ++++C WS AP C V C + +G+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1292 LKGSSVSHCVLVGMRSLWNNSVPVC 1316
L GS C S W+ VP C
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKC 283
Score = 83.6 bits (205), Expect = 2e-15
Identities = 74/285 (25%), Positives = 112/285 (39%), Gaps = 30/285 (10%)
Query: 166 CGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 225
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 226 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 282
+ C P + NG V N + + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPANGT-YEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 283 LNK---WEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG-----YDLR 333
W + P C +V C PPP + + + T + + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 334 GAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVL--FPVNLQLGAKVDFVCDEGFQ 391
G +++ C WS AAP C+V C + NG+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 392 LKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKP 436
L GS C S W+ VP C ++ S P +G P
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKCLKVSTSSTTKSPASSASGYP 303
Score = 83.6 bits (205), Expect = 2e-15
Identities = 74/285 (25%), Positives = 113/285 (39%), Gaps = 30/285 (10%)
Query: 616 CGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 675
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 676 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 731
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 732 --ALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG-----YDLR 783
++ W + P C +V C PPP + + + T + + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 784 GAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVL--FPVNLQLGAKVDFVCDEGFQ 841
G +++ C WS AAP C+V C + NG+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 842 LKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKP 886
L GS C S W+ VP C ++ S P +G P
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKCLKVSTSSTTKSPASSASGYP 303
Score = 73.6 bits (179), Expect = 2e-12
Identities = 68/274 (24%), Positives = 112/274 (40%), Gaps = 30/274 (10%)
Query: 1140 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP--RRVKCQALNKWEP-ELPSCSR- 1195
PP E L+ + + + E V+++C+ G+ P C + W P +C R
Sbjct: 38 PPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRE 97
Query: 1196 VCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD---WSPEAPR 1252
C + L+G+ P++ + G ++ + C GY L G L+C +G WS + P
Sbjct: 98 TCPYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPI 156
Query: 1253 CAVKSCDDFLGQLPHGRVLFP--LNLQLGAKVSFVCD-----EGFRLKGSSVSHCVLVGM 1305
C C ++ +G+ F + V++ CD + F L G S +C G
Sbjct: 157 CEKVLCTP-PPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC---GD 212
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
S+W+ + P C+ + C P + NG+ Y + + CD F L G
Sbjct: 213 NSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECD------KGFYLDGS 265
Query: 1366 STIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTP 1399
TI C S N W P P+C + K+P
Sbjct: 266 DTIVCDS----NSTWDPPVPKCLKVSTSSTTKSP 295
Score = 63.9 bits (154), Expect = 2e-09
Identities = 62/251 (24%), Positives = 100/251 (39%), Gaps = 27/251 (10%)
Query: 1277 QLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTP 1336
++G +V + C +G+ +H + + S C CP LNG+
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA- 113
Query: 1337 SGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGN-GVWSSPAPRCELSVRAGH 1395
+G +G ++ + C+ + LIGE + C + G+ +WS P CE +
Sbjct: 114 NGTYEFGYQMHFICNEG------YYLIGEEILYC--ELKGSVAIWSGKPPICEKVL---- 161
Query: 1396 CKTPEQFPFASPTIP-INDFEFPVGTSLNYECRPGYFGKMFS------ISCLENLVWSSV 1448
C P + T + FE+ ++ Y C P FS I C +N VWS
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRA 219
Query: 1449 EDNCRRKSCG-PPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTW 1507
C+ C P E + + +TV + C++GF L GS + C +N TW
Sbjct: 220 APECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVC---DSNSTW 276
Query: 1508 DKKAPICEIIS 1518
D P C +S
Sbjct: 277 DPPVPKCLKVS 287
>gi|27502415 CD46 antigen, complement regulatory protein isoform 9
precursor [Homo sapiens]
Length = 363
Score = 154 bits (390), Expect = 6e-37
Identities = 94/277 (33%), Positives = 131/277 (47%), Gaps = 13/277 (4%)
Query: 25 GSLLAVVVLLALPVAWGQCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYSGRP--- 81
G LLA +VLL + C P + + IG ++Y+C+ GY P
Sbjct: 18 GLLLAAMVLLLYSFS-DACEEPPTFEAMELIGKPKPY-YEIGERVDYKCKKGYFYIPPLA 75
Query: 82 FSIICLKNSVWTGAKD-RCRRKSCRNPPDPVNGMVHVIKGI-QFGSQIKYSCTKGYRLIG 139
IC +N W D C R++C DP+NG G +FG Q+ + C +GY LIG
Sbjct: 76 THTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIG 135
Query: 140 SSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGS 199
C + G IW + PIC+++ C PP I NG + E F Y VTY C+P +
Sbjct: 136 EEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP-A 194
Query: 200 GGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLN 259
G F L+GE +IYC N +WS AP+C + KC P VENG +S F
Sbjct: 195 PGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-KCRFPVVENGKQISGFGKKFYYK 249
Query: 260 EVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 296
V F C GF + G + C + + W+P +P C +V
Sbjct: 250 ATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 148 bits (374), Expect = 5e-35
Identities = 84/239 (35%), Positives = 113/239 (47%), Gaps = 11/239 (4%)
Query: 1416 FPVGTSLNYECRPGYF---GKMFSISCLENLVWSSVEDN-CRRKSCGPPPEPFNGM-VHI 1470
+ +G ++Y+C+ GYF C N W V D+ C R++C +P NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1471 NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDF 1530
N +FG +++ CNEG+ LIG C + G+ W K PICE + C PPP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1531 YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNK 1590
+ F VTY C P G F L+GE +IYC VWS P C K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAP-GPDPFSLIGESTIYCGDN----SVWSRAAPEC-KVVK 227
Query: 1591 CTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV 1649
C P VEN ++ G F + F C GF + GS T+ C +N W P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 147 bits (370), Expect = 1e-34
Identities = 85/239 (35%), Positives = 119/239 (49%), Gaps = 11/239 (4%)
Query: 513 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 567
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 568 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDF 627
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 628 ISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 687
+ E F Y VTY C+P + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDP-APGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 688 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 746
C P VENG +S F V F C GF + G + C + + W+P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 143 bits (361), Expect = 1e-33
Identities = 84/239 (35%), Positives = 118/239 (49%), Gaps = 11/239 (4%)
Query: 963 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 1017
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1018 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDF 1077
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1078 ISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 1137
+ E F Y VTY C+ + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCD-PAPGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 1138 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 1196
C P VENG +S F V F C GF + G + C + + W+P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 132 bits (331), Expect = 5e-30
Identities = 88/283 (31%), Positives = 128/283 (45%), Gaps = 18/283 (6%)
Query: 740 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 797
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 798 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 855
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 856 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGE 915
++W+ P+CE++ C PP I NG+HT +EVF + AV Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 916 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 975
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 976 EYY-GRPFSITCLDNLVWSSPKDVCKRKS----CKTPPDPVNG 1013
+Y +I C N W P C + S K+P +G
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSASG 301
Score = 130 bits (327), Expect = 1e-29
Identities = 87/283 (30%), Positives = 127/283 (44%), Gaps = 18/283 (6%)
Query: 290 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 347
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 348 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 405
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 406 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGE 465
++W+ P+CE++ C PP I NG+HT +EVF + V Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 466 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 525
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 526 EYY-GRPFSITCLDNLVWSSPKDVCKRKS----CKTPPDPVNG 563
+Y +I C N W P C + S K+P +G
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSASG 301
Score = 124 bits (310), Expect = 1e-27
Identities = 78/268 (29%), Positives = 120/268 (44%), Gaps = 14/268 (5%)
Query: 1647 SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLH--CTPQGDWSPEAP 1704
S C+ PP E + + G+ V Y C+ Y + H C W P +
Sbjct: 32 SDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 1705 RCTVKSCDDFLGQLPHGRVLLPLN--LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALW 1762
+ ++ +G+ + P N + G ++ F+C+EG+ L G +C L G A+W
Sbjct: 92 DACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 1763 NSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIR 1822
+ P+CE++ C PP I NG+HT + Y ++Y+CD P F+LIGES+I
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIY 209
Query: 1823 CTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYL 1882
C N VWS AP C++ C P ++NG I G + T+ + CD G+
Sbjct: 210 CGD----NSVWSRAAPECKV---VKCRF-PVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1883 LVGKGFIFCTDQGIWSQLDHYCKEVNCS 1910
L G I C W C +V+ S
Sbjct: 262 LDGSDTIVCDSNSTWDPPVPKCLKVSTS 289
Score = 115 bits (288), Expect = 4e-25
Identities = 80/274 (29%), Positives = 122/274 (44%), Gaps = 21/274 (7%)
Query: 1190 LPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH--CTPQGDWS 1247
L S S C+ PP E + + G+ V Y C+ GY + H C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 1248 PEAPRCAVKSCDDFLGQLPHGRVLFPLN--LQLGAKVSFVCDEGFRLKGSSVSHCVLVGM 1305
P + + ++ +G+ + P N + G ++ F+C+EG+ L G + +C L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
++W+ P+CE + C PP I NG+HT + Y ++Y+CDP P F+LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGE 205
Query: 1366 STIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDF--EFPVGTSLN 1423
STI C N VWS AP C++ C+ FP I+ F +F ++
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV----KCR----FPVVENGKQISGFGKKFYYKATVM 253
Query: 1424 YECRPG-YFGKMFSISCLENLVWSSVEDNCRRKS 1456
+EC G Y +I C N W C + S
Sbjct: 254 FECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVS 287
Score = 110 bits (274), Expect = 2e-23
Identities = 70/243 (28%), Positives = 115/243 (47%), Gaps = 21/243 (8%)
Query: 1730 QLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTP 1789
++G +V + C +G+ A+H + S C + CP LNG+
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1790 FGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGN-GVWSSPAPRCELSVPAAC 1848
G +G ++ + C+ + LIGE + C + +G+ +WS P CE C
Sbjct: 115 -GTYEFGYQMHFICNEG------YYLIGEEILYC--ELKGSVAIWSGKPPICE---KVLC 162
Query: 1849 PHPPKIQNGHYIGGHVSLYLPGMTISYICDPG-----YLLVGKGFIFCTDQGIWSQLDHY 1903
PPKI+NG + V ++ ++Y CDP + L+G+ I+C D +WS+
Sbjct: 163 TPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPE 222
Query: 1904 CKEVNCSFPLFMNGISKELE-MKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPL 1962
CK V C FP+ NG K++ K ++Y V +C+ G+ L+GS C ++ WDPP+
Sbjct: 223 CKVVKCRFPVVENG--KQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 1963 AKC 1965
KC
Sbjct: 281 PKC 283
Score = 87.8 bits (216), Expect = 1e-16
Identities = 58/237 (24%), Positives = 90/237 (37%), Gaps = 13/237 (5%)
Query: 1022 QVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTN 1081
++G R++Y C G+ I + I N C R C NG + N
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1082 RENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP 1141
+ +G + + CN G + L+GE +YC V IWSG P C PP
Sbjct: 115 G-TYEFGYQMHFICNEG------YYLIGEEILYCELKGS-VAIWSGKPPICEKVLCTPPP 166
Query: 1142 NVENGILVSDNRSLFSLNEVVEFRCQPG-----FVMKGPRRVKCQALNKWEPELPSCSRV 1196
++NG +F + V + C P F + G + C + W P C V
Sbjct: 167 KIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVV 226
Query: 1197 CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1253
P + +G+ F V + C+ G+ L G+ ++ C W P P+C
Sbjct: 227 KCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 85.1 bits (209), Expect = 6e-16
Identities = 64/260 (24%), Positives = 98/260 (37%), Gaps = 19/260 (7%)
Query: 1456 SCGPPPEPFNGMVHINTDTQF---GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTW-DKKA 1511
+C PP F M I + G V+Y C +G+ I P T + N TW
Sbjct: 34 ACEEPPT-FEAMELIGKPKPYYEIGERVDYKCKKGYFYI-PPLATHTICDRNHTWLPVSD 91
Query: 1512 PICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSK 1571
C +C NG N T + G + + C+ G + L+GE +YC K
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGT-YEFGYQMHFICNEG------YYLIGEEILYCELK 144
Query: 1572 DDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPG-----FVMV 1626
V +WS PP C P+++N F + + + C P F ++
Sbjct: 145 GS-VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1627 GSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLR 1686
G T+ C N W P C V P + +G+ F V + C+ + L
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLD 263
Query: 1687 GAASLHCTPQGDWSPEAPRC 1706
G+ ++ C W P P+C
Sbjct: 264 GSDTIVCDSNSTWDPPVPKC 283
Score = 84.7 bits (208), Expect = 8e-16
Identities = 72/265 (27%), Positives = 108/265 (40%), Gaps = 30/265 (11%)
Query: 1066 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1125
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 1126 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 1181
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 1182 --ALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPG-----YDLR 1233
++ W + P C +V C PPP+I +G+HT S + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1234 GAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVL--FPLNLQLGAKVSFVCDEGFR 1291
G ++++C WS AP C V C + +G+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1292 LKGSSVSHCVLVGMRSLWNNSVPVC 1316
L GS C S W+ VP C
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKC 283
Score = 83.6 bits (205), Expect = 2e-15
Identities = 74/285 (25%), Positives = 112/285 (39%), Gaps = 30/285 (10%)
Query: 166 CGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 225
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 226 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQA 282
+ C P + NG V N + + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPANGT-YEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 283 LNK---WEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG-----YDLR 333
W + P C +V C PPP + + + T + + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 334 GAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVL--FPVNLQLGAKVDFVCDEGFQ 391
G +++ C WS AAP C+V C + NG+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 392 LKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKP 436
L GS C S W+ VP C ++ S P +G P
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKCLKVSTSSTTKSPASSASGYP 303
Score = 83.6 bits (205), Expect = 2e-15
Identities = 74/285 (25%), Positives = 113/285 (39%), Gaps = 30/285 (10%)
Query: 616 CGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 675
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 676 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 731
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 732 --ALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG-----YDLR 783
++ W + P C +V C PPP + + + T + + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 784 GAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVL--FPVNLQLGAKVDFVCDEGFQ 841
G +++ C WS AAP C+V C + NG+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 842 LKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKP 886
L GS C S W+ VP C ++ S P +G P
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKCLKVSTSSTTKSPASSASGYP 303
Score = 73.6 bits (179), Expect = 2e-12
Identities = 68/274 (24%), Positives = 112/274 (40%), Gaps = 30/274 (10%)
Query: 1140 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP--RRVKCQALNKWEP-ELPSCSR- 1195
PP E L+ + + + E V+++C+ G+ P C + W P +C R
Sbjct: 38 PPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRE 97
Query: 1196 VCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD---WSPEAPR 1252
C + L+G+ P++ + G ++ + C GY L G L+C +G WS + P
Sbjct: 98 TCPYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPI 156
Query: 1253 CAVKSCDDFLGQLPHGRVLFP--LNLQLGAKVSFVCD-----EGFRLKGSSVSHCVLVGM 1305
C C ++ +G+ F + V++ CD + F L G S +C G
Sbjct: 157 CEKVLCTP-PPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC---GD 212
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
S+W+ + P C+ + C P + NG+ Y + + CD F L G
Sbjct: 213 NSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECD------KGFYLDGS 265
Query: 1366 STIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTP 1399
TI C S N W P P+C + K+P
Sbjct: 266 DTIVCDS----NSTWDPPVPKCLKVSTSSTTKSP 295
Score = 63.9 bits (154), Expect = 2e-09
Identities = 62/251 (24%), Positives = 100/251 (39%), Gaps = 27/251 (10%)
Query: 1277 QLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTP 1336
++G +V + C +G+ +H + + S C CP LNG+
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA- 113
Query: 1337 SGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGN-GVWSSPAPRCELSVRAGH 1395
+G +G ++ + C+ + LIGE + C + G+ +WS P CE +
Sbjct: 114 NGTYEFGYQMHFICNEG------YYLIGEEILYC--ELKGSVAIWSGKPPICEKVL---- 161
Query: 1396 CKTPEQFPFASPTIP-INDFEFPVGTSLNYECRPGYFGKMFS------ISCLENLVWSSV 1448
C P + T + FE+ ++ Y C P FS I C +N VWS
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRA 219
Query: 1449 EDNCRRKSCG-PPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTW 1507
C+ C P E + + +TV + C++GF L GS + C +N TW
Sbjct: 220 APECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVC---DSNSTW 276
Query: 1508 DKKAPICEIIS 1518
D P C +S
Sbjct: 277 DPPVPKCLKVS 287
>gi|27502407 CD46 antigen, complement regulatory protein isoform 3
precursor [Homo sapiens]
Length = 377
Score = 154 bits (390), Expect = 6e-37
Identities = 94/277 (33%), Positives = 131/277 (47%), Gaps = 13/277 (4%)
Query: 25 GSLLAVVVLLALPVAWGQCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYSGRP--- 81
G LLA +VLL + C P + + IG ++Y+C+ GY P
Sbjct: 18 GLLLAAMVLLLYSFS-DACEEPPTFEAMELIGKPKPY-YEIGERVDYKCKKGYFYIPPLA 75
Query: 82 FSIICLKNSVWTGAKD-RCRRKSCRNPPDPVNGMVHVIKGI-QFGSQIKYSCTKGYRLIG 139
IC +N W D C R++C DP+NG G +FG Q+ + C +GY LIG
Sbjct: 76 THTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIG 135
Query: 140 SSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGS 199
C + G IW + PIC+++ C PP I NG + E F Y VTY C+P +
Sbjct: 136 EEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP-A 194
Query: 200 GGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLN 259
G F L+GE +IYC N +WS AP+C + KC P VENG +S F
Sbjct: 195 PGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-KCRFPVVENGKQISGFGKKFYYK 249
Query: 260 EVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 296
V F C GF + G + C + + W+P +P C +V
Sbjct: 250 ATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 148 bits (374), Expect = 5e-35
Identities = 84/239 (35%), Positives = 113/239 (47%), Gaps = 11/239 (4%)
Query: 1416 FPVGTSLNYECRPGYF---GKMFSISCLENLVWSSVEDN-CRRKSCGPPPEPFNGM-VHI 1470
+ +G ++Y+C+ GYF C N W V D+ C R++C +P NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1471 NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDF 1530
N +FG +++ CNEG+ LIG C + G+ W K PICE + C PPP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1531 YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNK 1590
+ F VTY C P G F L+GE +IYC VWS P C K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAP-GPDPFSLIGESTIYCGDN----SVWSRAAPEC-KVVK 227
Query: 1591 CTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV 1649
C P VEN ++ G F + F C GF + GS T+ C +N W P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 147 bits (370), Expect = 1e-34
Identities = 85/239 (35%), Positives = 119/239 (49%), Gaps = 11/239 (4%)
Query: 513 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 567
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 568 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDF 627
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 628 ISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 687
+ E F Y VTY C+P + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDP-APGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 688 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 746
C P VENG +S F V F C GF + G + C + + W+P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 143 bits (361), Expect = 1e-33
Identities = 84/239 (35%), Positives = 118/239 (49%), Gaps = 11/239 (4%)
Query: 963 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 1017
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1018 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDF 1077
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1078 ISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 1137
+ E F Y VTY C+ + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCD-PAPGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 1138 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 1196
C P VENG +S F V F C GF + G + C + + W+P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 132 bits (331), Expect = 5e-30
Identities = 88/283 (31%), Positives = 128/283 (45%), Gaps = 18/283 (6%)
Query: 740 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 797
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 798 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 855
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 856 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGE 915
++W+ P+CE++ C PP I NG+HT +EVF + AV Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 916 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 975
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 976 EYY-GRPFSITCLDNLVWSSPKDVCKRKS----CKTPPDPVNG 1013
+Y +I C N W P C + S K+P +G
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSASG 301
Score = 130 bits (327), Expect = 1e-29
Identities = 87/283 (30%), Positives = 127/283 (44%), Gaps = 18/283 (6%)
Query: 290 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 347
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 348 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 405
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 406 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGE 465
++W+ P+CE++ C PP I NG+HT +EVF + V Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 466 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 525
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 526 EYY-GRPFSITCLDNLVWSSPKDVCKRKS----CKTPPDPVNG 563
+Y +I C N W P C + S K+P +G
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSASG 301
Score = 124 bits (310), Expect = 1e-27
Identities = 78/268 (29%), Positives = 120/268 (44%), Gaps = 14/268 (5%)
Query: 1647 SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLH--CTPQGDWSPEAP 1704
S C+ PP E + + G+ V Y C+ Y + H C W P +
Sbjct: 32 SDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 1705 RCTVKSCDDFLGQLPHGRVLLPLN--LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALW 1762
+ ++ +G+ + P N + G ++ F+C+EG+ L G +C L G A+W
Sbjct: 92 DACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 1763 NSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIR 1822
+ P+CE++ C PP I NG+HT + Y ++Y+CD P F+LIGES+I
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIY 209
Query: 1823 CTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYL 1882
C N VWS AP C++ C P ++NG I G + T+ + CD G+
Sbjct: 210 CGD----NSVWSRAAPECKV---VKCRF-PVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1883 LVGKGFIFCTDQGIWSQLDHYCKEVNCS 1910
L G I C W C +V+ S
Sbjct: 262 LDGSDTIVCDSNSTWDPPVPKCLKVSTS 289
Score = 115 bits (288), Expect = 4e-25
Identities = 80/274 (29%), Positives = 122/274 (44%), Gaps = 21/274 (7%)
Query: 1190 LPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH--CTPQGDWS 1247
L S S C+ PP E + + G+ V Y C+ GY + H C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 1248 PEAPRCAVKSCDDFLGQLPHGRVLFPLN--LQLGAKVSFVCDEGFRLKGSSVSHCVLVGM 1305
P + + ++ +G+ + P N + G ++ F+C+EG+ L G + +C L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
++W+ P+CE + C PP I NG+HT + Y ++Y+CDP P F+LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGE 205
Query: 1366 STIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDF--EFPVGTSLN 1423
STI C N VWS AP C++ C+ FP I+ F +F ++
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV----KCR----FPVVENGKQISGFGKKFYYKATVM 253
Query: 1424 YECRPG-YFGKMFSISCLENLVWSSVEDNCRRKS 1456
+EC G Y +I C N W C + S
Sbjct: 254 FECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVS 287
Score = 110 bits (274), Expect = 2e-23
Identities = 70/243 (28%), Positives = 115/243 (47%), Gaps = 21/243 (8%)
Query: 1730 QLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTP 1789
++G +V + C +G+ A+H + S C + CP LNG+
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1790 FGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGN-GVWSSPAPRCELSVPAAC 1848
G +G ++ + C+ + LIGE + C + +G+ +WS P CE C
Sbjct: 115 -GTYEFGYQMHFICNEG------YYLIGEEILYC--ELKGSVAIWSGKPPICE---KVLC 162
Query: 1849 PHPPKIQNGHYIGGHVSLYLPGMTISYICDPG-----YLLVGKGFIFCTDQGIWSQLDHY 1903
PPKI+NG + V ++ ++Y CDP + L+G+ I+C D +WS+
Sbjct: 163 TPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPE 222
Query: 1904 CKEVNCSFPLFMNGISKELE-MKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPL 1962
CK V C FP+ NG K++ K ++Y V +C+ G+ L+GS C ++ WDPP+
Sbjct: 223 CKVVKCRFPVVENG--KQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 1963 AKC 1965
KC
Sbjct: 281 PKC 283
Score = 87.8 bits (216), Expect = 1e-16
Identities = 58/237 (24%), Positives = 90/237 (37%), Gaps = 13/237 (5%)
Query: 1022 QVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTN 1081
++G R++Y C G+ I + I N C R C NG + N
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1082 RENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP 1141
+ +G + + CN G + L+GE +YC V IWSG P C PP
Sbjct: 115 G-TYEFGYQMHFICNEG------YYLIGEEILYCELKGS-VAIWSGKPPICEKVLCTPPP 166
Query: 1142 NVENGILVSDNRSLFSLNEVVEFRCQPG-----FVMKGPRRVKCQALNKWEPELPSCSRV 1196
++NG +F + V + C P F + G + C + W P C V
Sbjct: 167 KIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVV 226
Query: 1197 CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1253
P + +G+ F V + C+ G+ L G+ ++ C W P P+C
Sbjct: 227 KCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 85.1 bits (209), Expect = 6e-16
Identities = 64/260 (24%), Positives = 98/260 (37%), Gaps = 19/260 (7%)
Query: 1456 SCGPPPEPFNGMVHINTDTQF---GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTW-DKKA 1511
+C PP F M I + G V+Y C +G+ I P T + N TW
Sbjct: 34 ACEEPPT-FEAMELIGKPKPYYEIGERVDYKCKKGYFYI-PPLATHTICDRNHTWLPVSD 91
Query: 1512 PICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSK 1571
C +C NG N T + G + + C+ G + L+GE +YC K
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGT-YEFGYQMHFICNEG------YYLIGEEILYCELK 144
Query: 1572 DDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPG-----FVMV 1626
V +WS PP C P+++N F + + + C P F ++
Sbjct: 145 GS-VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1627 GSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLR 1686
G T+ C N W P C V P + +G+ F V + C+ + L
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLD 263
Query: 1687 GAASLHCTPQGDWSPEAPRC 1706
G+ ++ C W P P+C
Sbjct: 264 GSDTIVCDSNSTWDPPVPKC 283
Score = 84.7 bits (208), Expect = 8e-16
Identities = 72/265 (27%), Positives = 108/265 (40%), Gaps = 30/265 (11%)
Query: 1066 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1125
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 1126 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 1181
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 1182 --ALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPG-----YDLR 1233
++ W + P C +V C PPP+I +G+HT S + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1234 GAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVL--FPLNLQLGAKVSFVCDEGFR 1291
G ++++C WS AP C V C + +G+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1292 LKGSSVSHCVLVGMRSLWNNSVPVC 1316
L GS C S W+ VP C
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKC 283
Score = 84.3 bits (207), Expect = 1e-15
Identities = 79/306 (25%), Positives = 119/306 (38%), Gaps = 32/306 (10%)
Query: 616 CGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 675
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 676 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 731
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 732 --ALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG-----YDLR 783
++ W + P C +V C PPP + + + T + + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 784 GAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVL--FPVNLQLGAKVDFVCDEGFQ 841
G +++ C WS AAP C+V C + NG+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 842 LKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCD 901
L GS C S W+ VP C ++ S P +G P NY
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKCLKVSTSSTTKSPASSASGPRPTYKP--PVSNYPGY 316
Query: 902 PHPDRG 907
P P+ G
Sbjct: 317 PKPEEG 322
Score = 74.3 bits (181), Expect = 1e-12
Identities = 77/305 (25%), Positives = 125/305 (40%), Gaps = 40/305 (13%)
Query: 1140 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP--RRVKCQALNKWEP-ELPSCSR- 1195
PP E L+ + + + E V+++C+ G+ P C + W P +C R
Sbjct: 38 PPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRE 97
Query: 1196 VCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD---WSPEAPR 1252
C + L+G+ P++ + G ++ + C GY L G L+C +G WS + P
Sbjct: 98 TCPYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPI 156
Query: 1253 CAVKSCDDFLGQLPHGRVLFP--LNLQLGAKVSFVCD-----EGFRLKGSSVSHCVLVGM 1305
C C ++ +G+ F + V++ CD + F L G S +C G
Sbjct: 157 CEKVLCTP-PPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC---GD 212
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
S+W+ + P C+ + C P + NG+ Y + + CD F L G
Sbjct: 213 NSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECD------KGFYLDGS 265
Query: 1366 STIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYE 1425
TI C S N W P P+C + K+P +S + P ++ PV NY
Sbjct: 266 DTIVCDS----NSTWDPPVPKCLKVSTSSTTKSPA----SSASGPRPTYKPPVS---NY- 313
Query: 1426 CRPGY 1430
PGY
Sbjct: 314 --PGY 316
Score = 63.9 bits (154), Expect = 2e-09
Identities = 62/251 (24%), Positives = 100/251 (39%), Gaps = 27/251 (10%)
Query: 1277 QLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTP 1336
++G +V + C +G+ +H + + S C CP LNG+
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA- 113
Query: 1337 SGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGN-GVWSSPAPRCELSVRAGH 1395
+G +G ++ + C+ + LIGE + C + G+ +WS P CE +
Sbjct: 114 NGTYEFGYQMHFICNEG------YYLIGEEILYC--ELKGSVAIWSGKPPICEKVL---- 161
Query: 1396 CKTPEQFPFASPTIP-INDFEFPVGTSLNYECRPGYFGKMFS------ISCLENLVWSSV 1448
C P + T + FE+ ++ Y C P FS I C +N VWS
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRA 219
Query: 1449 EDNCRRKSCG-PPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTW 1507
C+ C P E + + +TV + C++GF L GS + C +N TW
Sbjct: 220 APECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVC---DSNSTW 276
Query: 1508 DKKAPICEIIS 1518
D P C +S
Sbjct: 277 DPPVPKCLKVS 287
>gi|24432108 CD46 antigen, complement regulatory protein isoform 4
precursor [Homo sapiens]
Length = 384
Score = 154 bits (390), Expect = 6e-37
Identities = 94/277 (33%), Positives = 131/277 (47%), Gaps = 13/277 (4%)
Query: 25 GSLLAVVVLLALPVAWGQCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYSGRP--- 81
G LLA +VLL + C P + + IG ++Y+C+ GY P
Sbjct: 18 GLLLAAMVLLLYSFS-DACEEPPTFEAMELIGKPKPY-YEIGERVDYKCKKGYFYIPPLA 75
Query: 82 FSIICLKNSVWTGAKD-RCRRKSCRNPPDPVNGMVHVIKGI-QFGSQIKYSCTKGYRLIG 139
IC +N W D C R++C DP+NG G +FG Q+ + C +GY LIG
Sbjct: 76 THTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIG 135
Query: 140 SSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGS 199
C + G IW + PIC+++ C PP I NG + E F Y VTY C+P +
Sbjct: 136 EEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP-A 194
Query: 200 GGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLN 259
G F L+GE +IYC N +WS AP+C + KC P VENG +S F
Sbjct: 195 PGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-KCRFPVVENGKQISGFGKKFYYK 249
Query: 260 EVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 296
V F C GF + G + C + + W+P +P C +V
Sbjct: 250 ATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 148 bits (374), Expect = 5e-35
Identities = 84/239 (35%), Positives = 113/239 (47%), Gaps = 11/239 (4%)
Query: 1416 FPVGTSLNYECRPGYF---GKMFSISCLENLVWSSVEDN-CRRKSCGPPPEPFNGM-VHI 1470
+ +G ++Y+C+ GYF C N W V D+ C R++C +P NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1471 NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDF 1530
N +FG +++ CNEG+ LIG C + G+ W K PICE + C PPP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1531 YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNK 1590
+ F VTY C P G F L+GE +IYC VWS P C K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAP-GPDPFSLIGESTIYCGDN----SVWSRAAPEC-KVVK 227
Query: 1591 CTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV 1649
C P VEN ++ G F + F C GF + GS T+ C +N W P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 147 bits (370), Expect = 1e-34
Identities = 85/239 (35%), Positives = 119/239 (49%), Gaps = 11/239 (4%)
Query: 513 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 567
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 568 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDF 627
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 628 ISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 687
+ E F Y VTY C+P + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDP-APGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 688 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 746
C P VENG +S F V F C GF + G + C + + W+P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 143 bits (361), Expect = 1e-33
Identities = 84/239 (35%), Positives = 118/239 (49%), Gaps = 11/239 (4%)
Query: 963 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 1017
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1018 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDF 1077
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1078 ISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 1137
+ E F Y VTY C+ + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCD-PAPGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 1138 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRV 1196
C P VENG +S F V F C GF + G + C + + W+P +P C +V
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKV 286
Score = 132 bits (331), Expect = 5e-30
Identities = 88/283 (31%), Positives = 128/283 (45%), Gaps = 18/283 (6%)
Query: 740 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 797
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 798 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 855
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 856 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGE 915
++W+ P+CE++ C PP I NG+HT +EVF + AV Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 916 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 975
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 976 EYY-GRPFSITCLDNLVWSSPKDVCKRKS----CKTPPDPVNG 1013
+Y +I C N W P C + S K+P +G
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSASG 301
Score = 130 bits (327), Expect = 1e-29
Identities = 87/283 (30%), Positives = 127/283 (44%), Gaps = 18/283 (6%)
Query: 290 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 347
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 348 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 405
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 406 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGE 465
++W+ P+CE++ C PP I NG+HT +EVF + V Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 466 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 525
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 526 EYY-GRPFSITCLDNLVWSSPKDVCKRKS----CKTPPDPVNG 563
+Y +I C N W P C + S K+P +G
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSASG 301
Score = 124 bits (310), Expect = 1e-27
Identities = 78/268 (29%), Positives = 120/268 (44%), Gaps = 14/268 (5%)
Query: 1647 SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLH--CTPQGDWSPEAP 1704
S C+ PP E + + G+ V Y C+ Y + H C W P +
Sbjct: 32 SDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 1705 RCTVKSCDDFLGQLPHGRVLLPLN--LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALW 1762
+ ++ +G+ + P N + G ++ F+C+EG+ L G +C L G A+W
Sbjct: 92 DACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 1763 NSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIR 1822
+ P+CE++ C PP I NG+HT + Y ++Y+CD P F+LIGES+I
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIY 209
Query: 1823 CTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYL 1882
C N VWS AP C++ C P ++NG I G + T+ + CD G+
Sbjct: 210 CGD----NSVWSRAAPECKV---VKCRF-PVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1883 LVGKGFIFCTDQGIWSQLDHYCKEVNCS 1910
L G I C W C +V+ S
Sbjct: 262 LDGSDTIVCDSNSTWDPPVPKCLKVSTS 289
Score = 115 bits (288), Expect = 4e-25
Identities = 80/274 (29%), Positives = 122/274 (44%), Gaps = 21/274 (7%)
Query: 1190 LPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH--CTPQGDWS 1247
L S S C+ PP E + + G+ V Y C+ GY + H C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 1248 PEAPRCAVKSCDDFLGQLPHGRVLFPLN--LQLGAKVSFVCDEGFRLKGSSVSHCVLVGM 1305
P + + ++ +G+ + P N + G ++ F+C+EG+ L G + +C L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
++W+ P+CE + C PP I NG+HT + Y ++Y+CDP P F+LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGE 205
Query: 1366 STIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDF--EFPVGTSLN 1423
STI C N VWS AP C++ C+ FP I+ F +F ++
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV----KCR----FPVVENGKQISGFGKKFYYKATVM 253
Query: 1424 YECRPG-YFGKMFSISCLENLVWSSVEDNCRRKS 1456
+EC G Y +I C N W C + S
Sbjct: 254 FECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVS 287
Score = 110 bits (274), Expect = 2e-23
Identities = 70/243 (28%), Positives = 115/243 (47%), Gaps = 21/243 (8%)
Query: 1730 QLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTP 1789
++G +V + C +G+ A+H + S C + CP LNG+
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1790 FGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGN-GVWSSPAPRCELSVPAAC 1848
G +G ++ + C+ + LIGE + C + +G+ +WS P CE C
Sbjct: 115 -GTYEFGYQMHFICNEG------YYLIGEEILYC--ELKGSVAIWSGKPPICE---KVLC 162
Query: 1849 PHPPKIQNGHYIGGHVSLYLPGMTISYICDPG-----YLLVGKGFIFCTDQGIWSQLDHY 1903
PPKI+NG + V ++ ++Y CDP + L+G+ I+C D +WS+
Sbjct: 163 TPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPE 222
Query: 1904 CKEVNCSFPLFMNGISKELE-MKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPL 1962
CK V C FP+ NG K++ K ++Y V +C+ G+ L+GS C ++ WDPP+
Sbjct: 223 CKVVKCRFPVVENG--KQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 1963 AKC 1965
KC
Sbjct: 281 PKC 283
Score = 87.8 bits (216), Expect = 1e-16
Identities = 58/237 (24%), Positives = 90/237 (37%), Gaps = 13/237 (5%)
Query: 1022 QVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTN 1081
++G R++Y C G+ I + I N C R C NG + N
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1082 RENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP 1141
+ +G + + CN G + L+GE +YC V IWSG P C PP
Sbjct: 115 G-TYEFGYQMHFICNEG------YYLIGEEILYCELKGS-VAIWSGKPPICEKVLCTPPP 166
Query: 1142 NVENGILVSDNRSLFSLNEVVEFRCQPG-----FVMKGPRRVKCQALNKWEPELPSCSRV 1196
++NG +F + V + C P F + G + C + W P C V
Sbjct: 167 KIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVV 226
Query: 1197 CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1253
P + +G+ F V + C+ G+ L G+ ++ C W P P+C
Sbjct: 227 KCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 85.1 bits (209), Expect = 6e-16
Identities = 64/260 (24%), Positives = 98/260 (37%), Gaps = 19/260 (7%)
Query: 1456 SCGPPPEPFNGMVHINTDTQF---GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTW-DKKA 1511
+C PP F M I + G V+Y C +G+ I P T + N TW
Sbjct: 34 ACEEPPT-FEAMELIGKPKPYYEIGERVDYKCKKGYFYI-PPLATHTICDRNHTWLPVSD 91
Query: 1512 PICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSK 1571
C +C NG N T + G + + C+ G + L+GE +YC K
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGT-YEFGYQMHFICNEG------YYLIGEEILYCELK 144
Query: 1572 DDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPG-----FVMV 1626
V +WS PP C P+++N F + + + C P F ++
Sbjct: 145 GS-VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1627 GSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLR 1686
G T+ C N W P C V P + +G+ F V + C+ + L
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLD 263
Query: 1687 GAASLHCTPQGDWSPEAPRC 1706
G+ ++ C W P P+C
Sbjct: 264 GSDTIVCDSNSTWDPPVPKC 283
Score = 84.7 bits (208), Expect = 8e-16
Identities = 72/265 (27%), Positives = 108/265 (40%), Gaps = 30/265 (11%)
Query: 1066 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1125
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 1126 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 1181
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 1182 --ALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPG-----YDLR 1233
++ W + P C +V C PPP+I +G+HT S + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1234 GAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVL--FPLNLQLGAKVSFVCDEGFR 1291
G ++++C WS AP C V C + +G+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1292 LKGSSVSHCVLVGMRSLWNNSVPVC 1316
L GS C S W+ VP C
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKC 283
Score = 84.3 bits (207), Expect = 1e-15
Identities = 79/306 (25%), Positives = 119/306 (38%), Gaps = 32/306 (10%)
Query: 616 CGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 675
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 676 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 731
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 732 --ALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG-----YDLR 783
++ W + P C +V C PPP + + + T + + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 784 GAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVL--FPVNLQLGAKVDFVCDEGFQ 841
G +++ C WS AAP C+V C + NG+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 842 LKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCD 901
L GS C S W+ VP C ++ S P +G P NY
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKCLKVSTSSTTKSPASSASGPRPTYKP--PVSNYPGY 316
Query: 902 PHPDRG 907
P P+ G
Sbjct: 317 PKPEEG 322
Score = 74.3 bits (181), Expect = 1e-12
Identities = 77/305 (25%), Positives = 125/305 (40%), Gaps = 40/305 (13%)
Query: 1140 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP--RRVKCQALNKWEP-ELPSCSR- 1195
PP E L+ + + + E V+++C+ G+ P C + W P +C R
Sbjct: 38 PPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRE 97
Query: 1196 VCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD---WSPEAPR 1252
C + L+G+ P++ + G ++ + C GY L G L+C +G WS + P
Sbjct: 98 TCPYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPI 156
Query: 1253 CAVKSCDDFLGQLPHGRVLFP--LNLQLGAKVSFVCD-----EGFRLKGSSVSHCVLVGM 1305
C C ++ +G+ F + V++ CD + F L G S +C G
Sbjct: 157 CEKVLCTP-PPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC---GD 212
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
S+W+ + P C+ + C P + NG+ Y + + CD F L G
Sbjct: 213 NSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECD------KGFYLDGS 265
Query: 1366 STIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYE 1425
TI C S N W P P+C + K+P +S + P ++ PV NY
Sbjct: 266 DTIVCDS----NSTWDPPVPKCLKVSTSSTTKSPA----SSASGPRPTYKPPVS---NY- 313
Query: 1426 CRPGY 1430
PGY
Sbjct: 314 --PGY 316
Score = 63.9 bits (154), Expect = 2e-09
Identities = 62/251 (24%), Positives = 100/251 (39%), Gaps = 27/251 (10%)
Query: 1277 QLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTP 1336
++G +V + C +G+ +H + + S C CP LNG+
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA- 113
Query: 1337 SGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDPHGN-GVWSSPAPRCELSVRAGH 1395
+G +G ++ + C+ + LIGE + C + G+ +WS P CE +
Sbjct: 114 NGTYEFGYQMHFICNEG------YYLIGEEILYC--ELKGSVAIWSGKPPICEKVL---- 161
Query: 1396 CKTPEQFPFASPTIP-INDFEFPVGTSLNYECRPGYFGKMFS------ISCLENLVWSSV 1448
C P + T + FE+ ++ Y C P FS I C +N VWS
Sbjct: 162 CTPPPKIKNGKHTFSEVEVFEYL--DAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRA 219
Query: 1449 EDNCRRKSCG-PPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTW 1507
C+ C P E + + +TV + C++GF L GS + C +N TW
Sbjct: 220 APECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVC---DSNSTW 276
Query: 1508 DKKAPICEIIS 1518
D P C +S
Sbjct: 277 DPPVPKCLKVS 287
>gi|27502411 CD46 antigen, complement regulatory protein isoform 6
precursor [Homo sapiens]
Length = 369
Score = 154 bits (388), Expect = 1e-36
Identities = 94/280 (33%), Positives = 132/280 (47%), Gaps = 13/280 (4%)
Query: 25 GSLLAVVVLLALPVAWGQCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYSGRP--- 81
G LLA +VLL + C P + + IG ++Y+C+ GY P
Sbjct: 18 GLLLAAMVLLLYSFS-DACEEPPTFEAMELIGKPKPY-YEIGERVDYKCKKGYFYIPPLA 75
Query: 82 FSIICLKNSVWTGAKD-RCRRKSCRNPPDPVNGMVHVIKGI-QFGSQIKYSCTKGYRLIG 139
IC +N W D C R++C DP+NG G +FG Q+ + C +GY LIG
Sbjct: 76 THTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIG 135
Query: 140 SSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGS 199
C + G IW + PIC+++ C PP I NG + E F Y VTY C+P +
Sbjct: 136 EEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP-A 194
Query: 200 GGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLN 259
G F L+GE +IYC N +WS AP+C + KC P VENG +S F
Sbjct: 195 PGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-KCRFPVVENGKQISGFGKKFYYK 249
Query: 260 EVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQP 299
V F C GF + G + C + + W+P +P C + +P
Sbjct: 250 ATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGPRP 289
Score = 147 bits (372), Expect = 8e-35
Identities = 84/242 (34%), Positives = 114/242 (47%), Gaps = 11/242 (4%)
Query: 1416 FPVGTSLNYECRPGYF---GKMFSISCLENLVWSSVEDN-CRRKSCGPPPEPFNGM-VHI 1470
+ +G ++Y+C+ GYF C N W V D+ C R++C +P NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1471 NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDF 1530
N +FG +++ CNEG+ LIG C + G+ W K PICE + C PPP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1531 YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNK 1590
+ F VTY C P G F L+GE +IYC VWS P C K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAP-GPDPFSLIGESTIYCGDN----SVWSRAAPEC-KVVK 227
Query: 1591 CTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVC 1650
C P VEN ++ G F + F C GF + GS T+ C +N W P +P C +
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGP 287
Query: 1651 QP 1652
+P
Sbjct: 288 RP 289
Score = 146 bits (368), Expect = 2e-34
Identities = 85/242 (35%), Positives = 120/242 (49%), Gaps = 11/242 (4%)
Query: 513 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 567
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 568 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDF 627
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 628 ISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 687
+ E F Y VTY C+P + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDP-APGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 688 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC 747
C P VENG +S F V F C GF + G + C + + W+P +P C +
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGP 287
Query: 748 QP 749
+P
Sbjct: 288 RP 289
Score = 142 bits (359), Expect = 3e-33
Identities = 84/242 (34%), Positives = 119/242 (49%), Gaps = 11/242 (4%)
Query: 963 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 1017
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1018 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDF 1077
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1078 ISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 1137
+ E F Y VTY C+ + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCD-PAPGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 1138 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC 1197
C P VENG +S F V F C GF + G + C + + W+P +P C +
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGP 287
Query: 1198 QP 1199
+P
Sbjct: 288 RP 289
Score = 132 bits (332), Expect = 3e-30
Identities = 87/278 (31%), Positives = 126/278 (45%), Gaps = 14/278 (5%)
Query: 740 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 797
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 798 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 855
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 856 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGE 915
++W+ P+CE++ C PP I NG+HT +EVF + AV Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 916 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 975
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 976 EYY-GRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 1012
+Y +I C N W P C + T PV+
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKCLKGPRPTYKPPVS 296
Score = 130 bits (328), Expect = 1e-29
Identities = 86/278 (30%), Positives = 125/278 (44%), Gaps = 14/278 (5%)
Query: 290 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 347
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 348 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 405
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 406 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGE 465
++W+ P+CE++ C PP I NG+HT +EVF + V Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 466 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 525
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 526 EYY-GRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 562
+Y +I C N W P C + T PV+
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKCLKGPRPTYKPPVS 296
Score = 122 bits (305), Expect = 5e-27
Identities = 75/255 (29%), Positives = 115/255 (45%), Gaps = 14/255 (5%)
Query: 1647 SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLH--CTPQGDWSPEAP 1704
S C+ PP E + + G+ V Y C+ Y + H C W P +
Sbjct: 32 SDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 1705 RCTVKSCDDFLGQLPHGRVLLPLN--LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALW 1762
+ ++ +G+ + P N + G ++ F+C+EG+ L G +C L G A+W
Sbjct: 92 DACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 1763 NSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIR 1822
+ P+CE++ C PP I NG+HT + Y ++Y+CD P F+LIGES+I
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIY 209
Query: 1823 CTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYL 1882
C N VWS AP C++ C P ++NG I G + T+ + CD G+
Sbjct: 210 CGD----NSVWSRAAPECKV---VKCRF-PVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1883 LVGKGFIFCTDQGIW 1897
L G I C W
Sbjct: 262 LDGSDTIVCDSNSTW 276
Score = 116 bits (290), Expect = 3e-25
Identities = 82/279 (29%), Positives = 124/279 (44%), Gaps = 24/279 (8%)
Query: 1190 LPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH--CTPQGDWS 1247
L S S C+ PP E + + G+ V Y C+ GY + H C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 1248 PEAPRCAVKSCDDFLGQLPHGRVLFPLN--LQLGAKVSFVCDEGFRLKGSSVSHCVLVGM 1305
P + + ++ +G+ + P N + G ++ F+C+EG+ L G + +C L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
++W+ P+CE + C PP I NG+HT + Y ++Y+CDP P F+LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGE 205
Query: 1366 STIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDF--EFPVGTSLN 1423
STI C N VWS AP C++ C+ FP I+ F +F ++
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV----KCR----FPVVENGKQISGFGKKFYYKATVM 253
Query: 1424 YECRPG-YFGKMFSISCLENLVWSSVEDNCRRKSCGPPP 1461
+EC G Y +I C N W C + GP P
Sbjct: 254 FECDKGFYLDGSDTIVCDSNSTWDPPVPKCLK---GPRP 289
Score = 110 bits (274), Expect = 2e-23
Identities = 70/243 (28%), Positives = 115/243 (47%), Gaps = 21/243 (8%)
Query: 1730 QLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTP 1789
++G +V + C +G+ A+H + S C + CP LNG+
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1790 FGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGN-GVWSSPAPRCELSVPAAC 1848
G +G ++ + C+ + LIGE + C + +G+ +WS P CE C
Sbjct: 115 -GTYEFGYQMHFICNEG------YYLIGEEILYC--ELKGSVAIWSGKPPICE---KVLC 162
Query: 1849 PHPPKIQNGHYIGGHVSLYLPGMTISYICDPG-----YLLVGKGFIFCTDQGIWSQLDHY 1903
PPKI+NG + V ++ ++Y CDP + L+G+ I+C D +WS+
Sbjct: 163 TPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPE 222
Query: 1904 CKEVNCSFPLFMNGISKELE-MKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPL 1962
CK V C FP+ NG K++ K ++Y V +C+ G+ L+GS C ++ WDPP+
Sbjct: 223 CKVVKCRFPVVENG--KQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 1963 AKC 1965
KC
Sbjct: 281 PKC 283
Score = 87.8 bits (216), Expect = 1e-16
Identities = 58/237 (24%), Positives = 90/237 (37%), Gaps = 13/237 (5%)
Query: 1022 QVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTN 1081
++G R++Y C G+ I + I N C R C NG + N
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1082 RENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP 1141
+ +G + + CN G + L+GE +YC V IWSG P C PP
Sbjct: 115 G-TYEFGYQMHFICNEG------YYLIGEEILYCELKGS-VAIWSGKPPICEKVLCTPPP 166
Query: 1142 NVENGILVSDNRSLFSLNEVVEFRCQPG-----FVMKGPRRVKCQALNKWEPELPSCSRV 1196
++NG +F + V + C P F + G + C + W P C V
Sbjct: 167 KIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVV 226
Query: 1197 CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1253
P + +G+ F V + C+ G+ L G+ ++ C W P P+C
Sbjct: 227 KCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 85.1 bits (209), Expect = 6e-16
Identities = 64/260 (24%), Positives = 98/260 (37%), Gaps = 19/260 (7%)
Query: 1456 SCGPPPEPFNGMVHINTDTQF---GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTW-DKKA 1511
+C PP F M I + G V+Y C +G+ I P T + N TW
Sbjct: 34 ACEEPPT-FEAMELIGKPKPYYEIGERVDYKCKKGYFYI-PPLATHTICDRNHTWLPVSD 91
Query: 1512 PICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSK 1571
C +C NG N T + G + + C+ G + L+GE +YC K
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGT-YEFGYQMHFICNEG------YYLIGEEILYCELK 144
Query: 1572 DDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPG-----FVMV 1626
V +WS PP C P+++N F + + + C P F ++
Sbjct: 145 GS-VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1627 GSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLR 1686
G T+ C N W P C V P + +G+ F V + C+ + L
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLD 263
Query: 1687 GAASLHCTPQGDWSPEAPRC 1706
G+ ++ C W P P+C
Sbjct: 264 GSDTIVCDSNSTWDPPVPKC 283
Score = 84.7 bits (208), Expect = 8e-16
Identities = 72/265 (27%), Positives = 108/265 (40%), Gaps = 30/265 (11%)
Query: 1066 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1125
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 1126 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 1181
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 1182 --ALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPG-----YDLR 1233
++ W + P C +V C PPP+I +G+HT S + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1234 GAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVL--FPLNLQLGAKVSFVCDEGFR 1291
G ++++C WS AP C V C + +G+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1292 LKGSSVSHCVLVGMRSLWNNSVPVC 1316
L GS C S W+ VP C
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKC 283
Score = 80.5 bits (197), Expect = 2e-14
Identities = 79/306 (25%), Positives = 117/306 (38%), Gaps = 47/306 (15%)
Query: 616 CGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 675
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 676 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 731
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 732 --ALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG-----YDLR 783
++ W + P C +V C PPP + + + T + + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 784 GAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVL--FPVNLQLGAKVDFVCDEGFQ 841
G +++ C WS AAP C+V C + NG+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 842 LKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCD 901
L GS C S W+ VP C + R T KP NY
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKC----------LKGPRPTYKP-------PVSNYPGY 301
Query: 902 PHPDRG 907
P P+ G
Sbjct: 302 PKPEEG 307
Score = 73.2 bits (178), Expect = 2e-12
Identities = 66/262 (25%), Positives = 108/262 (41%), Gaps = 30/262 (11%)
Query: 1140 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP--RRVKCQALNKWEP-ELPSCSR- 1195
PP E L+ + + + E V+++C+ G+ P C + W P +C R
Sbjct: 38 PPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRE 97
Query: 1196 VCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD---WSPEAPR 1252
C + L+G+ P++ + G ++ + C GY L G L+C +G WS + P
Sbjct: 98 TCPYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPI 156
Query: 1253 CAVKSCDDFLGQLPHGRVLFP--LNLQLGAKVSFVCD-----EGFRLKGSSVSHCVLVGM 1305
C C ++ +G+ F + V++ CD + F L G S +C G
Sbjct: 157 CEKVLCTP-PPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC---GD 212
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
S+W+ + P C+ + C P + NG+ Y + + CD F L G
Sbjct: 213 NSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECD------KGFYLDGS 265
Query: 1366 STIRCTSDPHGNGVWSSPAPRC 1387
TI C S N W P P+C
Sbjct: 266 DTIVCDS----NSTWDPPVPKC 283
>gi|27502409 CD46 antigen, complement regulatory protein isoform 5
precursor [Homo sapiens]
Length = 362
Score = 154 bits (388), Expect = 1e-36
Identities = 94/280 (33%), Positives = 132/280 (47%), Gaps = 13/280 (4%)
Query: 25 GSLLAVVVLLALPVAWGQCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYSGRP--- 81
G LLA +VLL + C P + + IG ++Y+C+ GY P
Sbjct: 18 GLLLAAMVLLLYSFS-DACEEPPTFEAMELIGKPKPY-YEIGERVDYKCKKGYFYIPPLA 75
Query: 82 FSIICLKNSVWTGAKD-RCRRKSCRNPPDPVNGMVHVIKGI-QFGSQIKYSCTKGYRLIG 139
IC +N W D C R++C DP+NG G +FG Q+ + C +GY LIG
Sbjct: 76 THTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIG 135
Query: 140 SSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGS 199
C + G IW + PIC+++ C PP I NG + E F Y VTY C+P +
Sbjct: 136 EEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP-A 194
Query: 200 GGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLN 259
G F L+GE +IYC N +WS AP+C + KC P VENG +S F
Sbjct: 195 PGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-KCRFPVVENGKQISGFGKKFYYK 249
Query: 260 EVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQP 299
V F C GF + G + C + + W+P +P C + +P
Sbjct: 250 ATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGPRP 289
Score = 147 bits (372), Expect = 8e-35
Identities = 84/242 (34%), Positives = 114/242 (47%), Gaps = 11/242 (4%)
Query: 1416 FPVGTSLNYECRPGYF---GKMFSISCLENLVWSSVEDN-CRRKSCGPPPEPFNGM-VHI 1470
+ +G ++Y+C+ GYF C N W V D+ C R++C +P NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1471 NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDF 1530
N +FG +++ CNEG+ LIG C + G+ W K PICE + C PPP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1531 YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNK 1590
+ F VTY C P G F L+GE +IYC VWS P C K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAP-GPDPFSLIGESTIYCGDN----SVWSRAAPEC-KVVK 227
Query: 1591 CTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVC 1650
C P VEN ++ G F + F C GF + GS T+ C +N W P +P C +
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGP 287
Query: 1651 QP 1652
+P
Sbjct: 288 RP 289
Score = 146 bits (368), Expect = 2e-34
Identities = 85/242 (35%), Positives = 120/242 (49%), Gaps = 11/242 (4%)
Query: 513 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 567
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 568 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDF 627
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 628 ISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 687
+ E F Y VTY C+P + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDP-APGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 688 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC 747
C P VENG +S F V F C GF + G + C + + W+P +P C +
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGP 287
Query: 748 QP 749
+P
Sbjct: 288 RP 289
Score = 142 bits (359), Expect = 3e-33
Identities = 84/242 (34%), Positives = 119/242 (49%), Gaps = 11/242 (4%)
Query: 963 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 1017
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1018 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDF 1077
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1078 ISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 1137
+ E F Y VTY C+ + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCD-PAPGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 1138 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC 1197
C P VENG +S F V F C GF + G + C + + W+P +P C +
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGP 287
Query: 1198 QP 1199
+P
Sbjct: 288 RP 289
Score = 132 bits (332), Expect = 3e-30
Identities = 87/278 (31%), Positives = 126/278 (45%), Gaps = 14/278 (5%)
Query: 740 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 797
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 798 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 855
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 856 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGE 915
++W+ P+CE++ C PP I NG+HT +EVF + AV Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 916 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 975
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 976 EYY-GRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 1012
+Y +I C N W P C + T PV+
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKCLKGPRPTYKPPVS 296
Score = 130 bits (328), Expect = 1e-29
Identities = 86/278 (30%), Positives = 125/278 (44%), Gaps = 14/278 (5%)
Query: 290 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 347
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 348 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 405
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 406 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGE 465
++W+ P+CE++ C PP I NG+HT +EVF + V Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 466 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 525
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 526 EYY-GRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 562
+Y +I C N W P C + T PV+
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKCLKGPRPTYKPPVS 296
Score = 122 bits (305), Expect = 5e-27
Identities = 75/255 (29%), Positives = 115/255 (45%), Gaps = 14/255 (5%)
Query: 1647 SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLH--CTPQGDWSPEAP 1704
S C+ PP E + + G+ V Y C+ Y + H C W P +
Sbjct: 32 SDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 1705 RCTVKSCDDFLGQLPHGRVLLPLN--LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALW 1762
+ ++ +G+ + P N + G ++ F+C+EG+ L G +C L G A+W
Sbjct: 92 DACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 1763 NSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIR 1822
+ P+CE++ C PP I NG+HT + Y ++Y+CD P F+LIGES+I
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIY 209
Query: 1823 CTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYL 1882
C N VWS AP C++ C P ++NG I G + T+ + CD G+
Sbjct: 210 CGD----NSVWSRAAPECKV---VKCRF-PVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1883 LVGKGFIFCTDQGIW 1897
L G I C W
Sbjct: 262 LDGSDTIVCDSNSTW 276
Score = 116 bits (290), Expect = 3e-25
Identities = 82/279 (29%), Positives = 124/279 (44%), Gaps = 24/279 (8%)
Query: 1190 LPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH--CTPQGDWS 1247
L S S C+ PP E + + G+ V Y C+ GY + H C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 1248 PEAPRCAVKSCDDFLGQLPHGRVLFPLN--LQLGAKVSFVCDEGFRLKGSSVSHCVLVGM 1305
P + + ++ +G+ + P N + G ++ F+C+EG+ L G + +C L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
++W+ P+CE + C PP I NG+HT + Y ++Y+CDP P F+LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGE 205
Query: 1366 STIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDF--EFPVGTSLN 1423
STI C N VWS AP C++ C+ FP I+ F +F ++
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV----KCR----FPVVENGKQISGFGKKFYYKATVM 253
Query: 1424 YECRPG-YFGKMFSISCLENLVWSSVEDNCRRKSCGPPP 1461
+EC G Y +I C N W C + GP P
Sbjct: 254 FECDKGFYLDGSDTIVCDSNSTWDPPVPKCLK---GPRP 289
Score = 110 bits (274), Expect = 2e-23
Identities = 70/243 (28%), Positives = 115/243 (47%), Gaps = 21/243 (8%)
Query: 1730 QLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTP 1789
++G +V + C +G+ A+H + S C + CP LNG+
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1790 FGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGN-GVWSSPAPRCELSVPAAC 1848
G +G ++ + C+ + LIGE + C + +G+ +WS P CE C
Sbjct: 115 -GTYEFGYQMHFICNEG------YYLIGEEILYC--ELKGSVAIWSGKPPICE---KVLC 162
Query: 1849 PHPPKIQNGHYIGGHVSLYLPGMTISYICDPG-----YLLVGKGFIFCTDQGIWSQLDHY 1903
PPKI+NG + V ++ ++Y CDP + L+G+ I+C D +WS+
Sbjct: 163 TPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPE 222
Query: 1904 CKEVNCSFPLFMNGISKELE-MKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPL 1962
CK V C FP+ NG K++ K ++Y V +C+ G+ L+GS C ++ WDPP+
Sbjct: 223 CKVVKCRFPVVENG--KQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 1963 AKC 1965
KC
Sbjct: 281 PKC 283
Score = 87.8 bits (216), Expect = 1e-16
Identities = 58/237 (24%), Positives = 90/237 (37%), Gaps = 13/237 (5%)
Query: 1022 QVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTN 1081
++G R++Y C G+ I + I N C R C NG + N
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1082 RENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP 1141
+ +G + + CN G + L+GE +YC V IWSG P C PP
Sbjct: 115 G-TYEFGYQMHFICNEG------YYLIGEEILYCELKGS-VAIWSGKPPICEKVLCTPPP 166
Query: 1142 NVENGILVSDNRSLFSLNEVVEFRCQPG-----FVMKGPRRVKCQALNKWEPELPSCSRV 1196
++NG +F + V + C P F + G + C + W P C V
Sbjct: 167 KIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVV 226
Query: 1197 CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1253
P + +G+ F V + C+ G+ L G+ ++ C W P P+C
Sbjct: 227 KCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 85.1 bits (209), Expect = 6e-16
Identities = 64/260 (24%), Positives = 98/260 (37%), Gaps = 19/260 (7%)
Query: 1456 SCGPPPEPFNGMVHINTDTQF---GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTW-DKKA 1511
+C PP F M I + G V+Y C +G+ I P T + N TW
Sbjct: 34 ACEEPPT-FEAMELIGKPKPYYEIGERVDYKCKKGYFYI-PPLATHTICDRNHTWLPVSD 91
Query: 1512 PICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSK 1571
C +C NG N T + G + + C+ G + L+GE +YC K
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGT-YEFGYQMHFICNEG------YYLIGEEILYCELK 144
Query: 1572 DDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPG-----FVMV 1626
V +WS PP C P+++N F + + + C P F ++
Sbjct: 145 GS-VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1627 GSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLR 1686
G T+ C N W P C V P + +G+ F V + C+ + L
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLD 263
Query: 1687 GAASLHCTPQGDWSPEAPRC 1706
G+ ++ C W P P+C
Sbjct: 264 GSDTIVCDSNSTWDPPVPKC 283
Score = 84.7 bits (208), Expect = 8e-16
Identities = 72/265 (27%), Positives = 108/265 (40%), Gaps = 30/265 (11%)
Query: 1066 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1125
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 1126 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 1181
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 1182 --ALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPG-----YDLR 1233
++ W + P C +V C PPP+I +G+HT S + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1234 GAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVL--FPLNLQLGAKVSFVCDEGFR 1291
G ++++C WS AP C V C + +G+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1292 LKGSSVSHCVLVGMRSLWNNSVPVC 1316
L GS C S W+ VP C
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKC 283
Score = 80.5 bits (197), Expect = 2e-14
Identities = 79/306 (25%), Positives = 117/306 (38%), Gaps = 47/306 (15%)
Query: 616 CGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 675
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 676 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 731
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 732 --ALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG-----YDLR 783
++ W + P C +V C PPP + + + T + + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 784 GAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVL--FPVNLQLGAKVDFVCDEGFQ 841
G +++ C WS AAP C+V C + NG+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 842 LKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCD 901
L GS C S W+ VP C + R T KP NY
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKC----------LKGPRPTYKP-------PVSNYPGY 301
Query: 902 PHPDRG 907
P P+ G
Sbjct: 302 PKPEEG 307
Score = 73.2 bits (178), Expect = 2e-12
Identities = 66/262 (25%), Positives = 108/262 (41%), Gaps = 30/262 (11%)
Query: 1140 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP--RRVKCQALNKWEP-ELPSCSR- 1195
PP E L+ + + + E V+++C+ G+ P C + W P +C R
Sbjct: 38 PPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRE 97
Query: 1196 VCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD---WSPEAPR 1252
C + L+G+ P++ + G ++ + C GY L G L+C +G WS + P
Sbjct: 98 TCPYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPI 156
Query: 1253 CAVKSCDDFLGQLPHGRVLFP--LNLQLGAKVSFVCD-----EGFRLKGSSVSHCVLVGM 1305
C C ++ +G+ F + V++ CD + F L G S +C G
Sbjct: 157 CEKVLCTP-PPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC---GD 212
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
S+W+ + P C+ + C P + NG+ Y + + CD F L G
Sbjct: 213 NSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECD------KGFYLDGS 265
Query: 1366 STIRCTSDPHGNGVWSSPAPRC 1387
TI C S N W P P+C
Sbjct: 266 DTIVCDS----NSTWDPPVPKC 283
>gi|27502405 CD46 antigen, complement regulatory protein isoform 14
precursor [Homo sapiens]
Length = 349
Score = 154 bits (388), Expect = 1e-36
Identities = 94/280 (33%), Positives = 132/280 (47%), Gaps = 13/280 (4%)
Query: 25 GSLLAVVVLLALPVAWGQCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYSGRP--- 81
G LLA +VLL + C P + + IG ++Y+C+ GY P
Sbjct: 18 GLLLAAMVLLLYSFS-DACEEPPTFEAMELIGKPKPY-YEIGERVDYKCKKGYFYIPPLA 75
Query: 82 FSIICLKNSVWTGAKD-RCRRKSCRNPPDPVNGMVHVIKGI-QFGSQIKYSCTKGYRLIG 139
IC +N W D C R++C DP+NG G +FG Q+ + C +GY LIG
Sbjct: 76 THTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIG 135
Query: 140 SSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGS 199
C + G IW + PIC+++ C PP I NG + E F Y VTY C+P +
Sbjct: 136 EEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP-A 194
Query: 200 GGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLN 259
G F L+GE +IYC N +WS AP+C + KC P VENG +S F
Sbjct: 195 PGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-KCRFPVVENGKQISGFGKKFYYK 249
Query: 260 EVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQP 299
V F C GF + G + C + + W+P +P C + +P
Sbjct: 250 ATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGPRP 289
Score = 147 bits (372), Expect = 8e-35
Identities = 84/242 (34%), Positives = 114/242 (47%), Gaps = 11/242 (4%)
Query: 1416 FPVGTSLNYECRPGYF---GKMFSISCLENLVWSSVEDN-CRRKSCGPPPEPFNGM-VHI 1470
+ +G ++Y+C+ GYF C N W V D+ C R++C +P NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1471 NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDF 1530
N +FG +++ CNEG+ LIG C + G+ W K PICE + C PPP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1531 YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNK 1590
+ F VTY C P G F L+GE +IYC VWS P C K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAP-GPDPFSLIGESTIYCGDN----SVWSRAAPEC-KVVK 227
Query: 1591 CTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVC 1650
C P VEN ++ G F + F C GF + GS T+ C +N W P +P C +
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGP 287
Query: 1651 QP 1652
+P
Sbjct: 288 RP 289
Score = 146 bits (368), Expect = 2e-34
Identities = 85/242 (35%), Positives = 120/242 (49%), Gaps = 11/242 (4%)
Query: 513 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 567
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 568 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDF 627
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 628 ISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 687
+ E F Y VTY C+P + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDP-APGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 688 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC 747
C P VENG +S F V F C GF + G + C + + W+P +P C +
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGP 287
Query: 748 QP 749
+P
Sbjct: 288 RP 289
Score = 142 bits (359), Expect = 3e-33
Identities = 84/242 (34%), Positives = 119/242 (49%), Gaps = 11/242 (4%)
Query: 963 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 1017
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1018 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDF 1077
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1078 ISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 1137
+ E F Y VTY C+ + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCD-PAPGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 1138 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC 1197
C P VENG +S F V F C GF + G + C + + W+P +P C +
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGP 287
Query: 1198 QP 1199
+P
Sbjct: 288 RP 289
Score = 132 bits (332), Expect = 3e-30
Identities = 87/278 (31%), Positives = 126/278 (45%), Gaps = 14/278 (5%)
Query: 740 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 797
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 798 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 855
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 856 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGE 915
++W+ P+CE++ C PP I NG+HT +EVF + AV Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 916 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 975
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 976 EYY-GRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 1012
+Y +I C N W P C + T PV+
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKCLKGPRPTYKPPVS 296
Score = 130 bits (328), Expect = 1e-29
Identities = 86/278 (30%), Positives = 125/278 (44%), Gaps = 14/278 (5%)
Query: 290 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 347
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 348 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 405
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 406 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGE 465
++W+ P+CE++ C PP I NG+HT +EVF + V Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 466 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 525
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 526 EYY-GRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVN 562
+Y +I C N W P C + T PV+
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKCLKGPRPTYKPPVS 296
Score = 122 bits (305), Expect = 5e-27
Identities = 75/255 (29%), Positives = 115/255 (45%), Gaps = 14/255 (5%)
Query: 1647 SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLH--CTPQGDWSPEAP 1704
S C+ PP E + + G+ V Y C+ Y + H C W P +
Sbjct: 32 SDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 1705 RCTVKSCDDFLGQLPHGRVLLPLN--LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALW 1762
+ ++ +G+ + P N + G ++ F+C+EG+ L G +C L G A+W
Sbjct: 92 DACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 1763 NSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIR 1822
+ P+CE++ C PP I NG+HT + Y ++Y+CD P F+LIGES+I
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIY 209
Query: 1823 CTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYL 1882
C N VWS AP C++ C P ++NG I G + T+ + CD G+
Sbjct: 210 CGD----NSVWSRAAPECKV---VKCRF-PVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1883 LVGKGFIFCTDQGIW 1897
L G I C W
Sbjct: 262 LDGSDTIVCDSNSTW 276
Score = 116 bits (290), Expect = 3e-25
Identities = 82/279 (29%), Positives = 124/279 (44%), Gaps = 24/279 (8%)
Query: 1190 LPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH--CTPQGDWS 1247
L S S C+ PP E + + G+ V Y C+ GY + H C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 1248 PEAPRCAVKSCDDFLGQLPHGRVLFPLN--LQLGAKVSFVCDEGFRLKGSSVSHCVLVGM 1305
P + + ++ +G+ + P N + G ++ F+C+EG+ L G + +C L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
++W+ P+CE + C PP I NG+HT + Y ++Y+CDP P F+LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGE 205
Query: 1366 STIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDF--EFPVGTSLN 1423
STI C N VWS AP C++ C+ FP I+ F +F ++
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV----KCR----FPVVENGKQISGFGKKFYYKATVM 253
Query: 1424 YECRPG-YFGKMFSISCLENLVWSSVEDNCRRKSCGPPP 1461
+EC G Y +I C N W C + GP P
Sbjct: 254 FECDKGFYLDGSDTIVCDSNSTWDPPVPKCLK---GPRP 289
Score = 110 bits (274), Expect = 2e-23
Identities = 70/243 (28%), Positives = 115/243 (47%), Gaps = 21/243 (8%)
Query: 1730 QLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTP 1789
++G +V + C +G+ A+H + S C + CP LNG+
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1790 FGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGN-GVWSSPAPRCELSVPAAC 1848
G +G ++ + C+ + LIGE + C + +G+ +WS P CE C
Sbjct: 115 -GTYEFGYQMHFICNEG------YYLIGEEILYC--ELKGSVAIWSGKPPICE---KVLC 162
Query: 1849 PHPPKIQNGHYIGGHVSLYLPGMTISYICDPG-----YLLVGKGFIFCTDQGIWSQLDHY 1903
PPKI+NG + V ++ ++Y CDP + L+G+ I+C D +WS+
Sbjct: 163 TPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPE 222
Query: 1904 CKEVNCSFPLFMNGISKELE-MKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPL 1962
CK V C FP+ NG K++ K ++Y V +C+ G+ L+GS C ++ WDPP+
Sbjct: 223 CKVVKCRFPVVENG--KQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 1963 AKC 1965
KC
Sbjct: 281 PKC 283
Score = 87.8 bits (216), Expect = 1e-16
Identities = 58/237 (24%), Positives = 90/237 (37%), Gaps = 13/237 (5%)
Query: 1022 QVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTN 1081
++G R++Y C G+ I + I N C R C NG + N
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1082 RENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP 1141
+ +G + + CN G + L+GE +YC V IWSG P C PP
Sbjct: 115 G-TYEFGYQMHFICNEG------YYLIGEEILYCELKGS-VAIWSGKPPICEKVLCTPPP 166
Query: 1142 NVENGILVSDNRSLFSLNEVVEFRCQPG-----FVMKGPRRVKCQALNKWEPELPSCSRV 1196
++NG +F + V + C P F + G + C + W P C V
Sbjct: 167 KIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVV 226
Query: 1197 CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1253
P + +G+ F V + C+ G+ L G+ ++ C W P P+C
Sbjct: 227 KCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 85.1 bits (209), Expect = 6e-16
Identities = 64/260 (24%), Positives = 98/260 (37%), Gaps = 19/260 (7%)
Query: 1456 SCGPPPEPFNGMVHINTDTQF---GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTW-DKKA 1511
+C PP F M I + G V+Y C +G+ I P T + N TW
Sbjct: 34 ACEEPPT-FEAMELIGKPKPYYEIGERVDYKCKKGYFYI-PPLATHTICDRNHTWLPVSD 91
Query: 1512 PICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSK 1571
C +C NG N T + G + + C+ G + L+GE +YC K
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGT-YEFGYQMHFICNEG------YYLIGEEILYCELK 144
Query: 1572 DDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPG-----FVMV 1626
V +WS PP C P+++N F + + + C P F ++
Sbjct: 145 GS-VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1627 GSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLR 1686
G T+ C N W P C V P + +G+ F V + C+ + L
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLD 263
Query: 1687 GAASLHCTPQGDWSPEAPRC 1706
G+ ++ C W P P+C
Sbjct: 264 GSDTIVCDSNSTWDPPVPKC 283
Score = 84.7 bits (208), Expect = 8e-16
Identities = 72/265 (27%), Positives = 108/265 (40%), Gaps = 30/265 (11%)
Query: 1066 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1125
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 1126 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 1181
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 1182 --ALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPG-----YDLR 1233
++ W + P C +V C PPP+I +G+HT S + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1234 GAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVL--FPLNLQLGAKVSFVCDEGFR 1291
G ++++C WS AP C V C + +G+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1292 LKGSSVSHCVLVGMRSLWNNSVPVC 1316
L GS C S W+ VP C
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKC 283
Score = 80.5 bits (197), Expect = 2e-14
Identities = 79/306 (25%), Positives = 117/306 (38%), Gaps = 47/306 (15%)
Query: 616 CGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 675
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 676 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 731
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 732 --ALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG-----YDLR 783
++ W + P C +V C PPP + + + T + + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 784 GAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVL--FPVNLQLGAKVDFVCDEGFQ 841
G +++ C WS AAP C+V C + NG+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 842 LKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCD 901
L GS C S W+ VP C + R T KP NY
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKC----------LKGPRPTYKP-------PVSNYPGY 301
Query: 902 PHPDRG 907
P P+ G
Sbjct: 302 PKPEEG 307
Score = 73.2 bits (178), Expect = 2e-12
Identities = 66/262 (25%), Positives = 108/262 (41%), Gaps = 30/262 (11%)
Query: 1140 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP--RRVKCQALNKWEP-ELPSCSR- 1195
PP E L+ + + + E V+++C+ G+ P C + W P +C R
Sbjct: 38 PPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRE 97
Query: 1196 VCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD---WSPEAPR 1252
C + L+G+ P++ + G ++ + C GY L G L+C +G WS + P
Sbjct: 98 TCPYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPI 156
Query: 1253 CAVKSCDDFLGQLPHGRVLFP--LNLQLGAKVSFVCD-----EGFRLKGSSVSHCVLVGM 1305
C C ++ +G+ F + V++ CD + F L G S +C G
Sbjct: 157 CEKVLCTP-PPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC---GD 212
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
S+W+ + P C+ + C P + NG+ Y + + CD F L G
Sbjct: 213 NSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECD------KGFYLDGS 265
Query: 1366 STIRCTSDPHGNGVWSSPAPRC 1387
TI C S N W P P+C
Sbjct: 266 DTIVCDS----NSTWDPPVPKC 283
>gi|27502419 CD46 antigen, complement regulatory protein isoform 11
precursor [Homo sapiens]
Length = 348
Score = 153 bits (387), Expect = 1e-36
Identities = 94/283 (33%), Positives = 132/283 (46%), Gaps = 13/283 (4%)
Query: 25 GSLLAVVVLLALPVAWGQCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGYSGRP--- 81
G LLA +VLL + C P + + IG ++Y+C+ GY P
Sbjct: 18 GLLLAAMVLLLYSFS-DACEEPPTFEAMELIGKPKPY-YEIGERVDYKCKKGYFYIPPLA 75
Query: 82 FSIICLKNSVWTGAKD-RCRRKSCRNPPDPVNGMVHVIKGI-QFGSQIKYSCTKGYRLIG 139
IC +N W D C R++C DP+NG G +FG Q+ + C +GY LIG
Sbjct: 76 THTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIG 135
Query: 140 SSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGS 199
C + G IW + PIC+++ C PP I NG + E F Y VTY C+P +
Sbjct: 136 EEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP-A 194
Query: 200 GGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLN 259
G F L+GE +IYC N +WS AP+C + KC P VENG +S F
Sbjct: 195 PGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-KCRFPVVENGKQISGFGKKFYYK 249
Query: 260 EVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVCQPPPD 302
V F C GF + G + C + + W+P +P C + P +
Sbjct: 250 ATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGYPKPEE 292
Score = 148 bits (374), Expect = 5e-35
Identities = 85/245 (34%), Positives = 114/245 (46%), Gaps = 11/245 (4%)
Query: 1416 FPVGTSLNYECRPGYF---GKMFSISCLENLVWSSVEDN-CRRKSCGPPPEPFNGM-VHI 1470
+ +G ++Y+C+ GYF C N W V D+ C R++C +P NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1471 NTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDF 1530
N +FG +++ CNEG+ LIG C + G+ W K PICE + C PPP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1531 YSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNK 1590
+ F VTY C P G F L+GE +IYC VWS P C K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDPAP-GPDPFSLIGESTIYCGDN----SVWSRAAPEC-KVVK 227
Query: 1591 CTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRVC 1650
C P VEN ++ G F + F C GF + GS T+ C +N W P +P C +
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGY 287
Query: 1651 QPPPE 1655
P E
Sbjct: 288 PKPEE 292
Score = 145 bits (367), Expect = 3e-34
Identities = 85/245 (34%), Positives = 120/245 (48%), Gaps = 11/245 (4%)
Query: 513 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 567
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 568 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQRIPCGLPPTIANGDF 627
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 628 ISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 687
+ E F Y VTY C+P + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCDP-APGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 688 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC 747
C P VENG +S F V F C GF + G + C + + W+P +P C +
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGY 287
Query: 748 QPPPD 752
P +
Sbjct: 288 PKPEE 292
Score = 143 bits (361), Expect = 1e-33
Identities = 85/245 (34%), Positives = 119/245 (48%), Gaps = 11/245 (4%)
Query: 963 FPIGTSLKYECRPEYYGRPFSIT---CLDNLVWSSPKD-VCKRKSCKTPPDPVNGM-VHV 1017
+ IG + Y+C+ Y+ P T C N W D C R++C DP+NG V
Sbjct: 54 YEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPA 113
Query: 1018 ITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDF 1077
+ G ++++ C G+ LIG C L G+ A WS KPPIC+++ C PP I NG
Sbjct: 114 NGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKH 173
Query: 1078 ISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNK 1137
+ E F Y VTY C+ + G F L+GE +IYC N +WS AP+C + K
Sbjct: 174 TFSEVEVFEYLDAVTYSCD-PAPGPDPFSLIGESTIYCGDN----SVWSRAAPECKVV-K 227
Query: 1138 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEPELPSCSRVC 1197
C P VENG +S F V F C GF + G + C + + W+P +P C +
Sbjct: 228 CRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGY 287
Query: 1198 QPPPE 1202
P E
Sbjct: 288 PKPEE 292
Score = 131 bits (330), Expect = 6e-30
Identities = 88/281 (31%), Positives = 127/281 (45%), Gaps = 18/281 (6%)
Query: 740 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 797
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 798 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 855
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 856 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGE 915
++W+ P+CE++ C PP I NG+HT +EVF + AV Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 916 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 975
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 976 EYY-GRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMV 1015
+Y +I C N W P C K P P G++
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKC----LKGYPKPEEGIL 295
Score = 130 bits (326), Expect = 2e-29
Identities = 87/281 (30%), Positives = 126/281 (44%), Gaps = 18/281 (6%)
Query: 290 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRG--AASMRCTPQGDWS 347
L S S C+ PP E + K + G+ V Y C+ GY A C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 348 PAAPTCEVKSCDDFMGQLLNGRVLFPVN--LQLGAKVDFVCDEGFQLKGSSASYCVLAGM 405
P + + ++ LNG+ + P N + G ++ F+C+EG+ L G YC L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 406 ESLWNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGE 465
++W+ P+CE++ C PP I NG+HT +EVF + V Y+CDP P F LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPG-PDPFSLIGE 205
Query: 466 STIRCTSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRP 525
STI C N VWS AP C ++ C+ P + + F ++ +EC
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV-KCRFP--VVENGKQISGFGKKFYYKATVMFECDK 258
Query: 526 EYY-GRPFSITCLDNLVWSSPKDVCKRKSCKTPPDPVNGMV 565
+Y +I C N W P C K P P G++
Sbjct: 259 GFYLDGSDTIVCDSNSTWDPPVPKC----LKGYPKPEEGIL 295
Score = 122 bits (305), Expect = 5e-27
Identities = 75/255 (29%), Positives = 115/255 (45%), Gaps = 14/255 (5%)
Query: 1647 SRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLH--CTPQGDWSPEAP 1704
S C+ PP E + + G+ V Y C+ Y + H C W P +
Sbjct: 32 SDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 1705 RCTVKSCDDFLGQLPHGRVLLPLN--LQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALW 1762
+ ++ +G+ + P N + G ++ F+C+EG+ L G +C L G A+W
Sbjct: 92 DACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIW 150
Query: 1763 NSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIR 1822
+ P+CE++ C PP I NG+HT + Y ++Y+CD P F+LIGES+I
Sbjct: 151 SGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGESTIY 209
Query: 1823 CTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYL 1882
C N VWS AP C++ C P ++NG I G + T+ + CD G+
Sbjct: 210 CGD----NSVWSRAAPECKV---VKCRF-PVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1883 LVGKGFIFCTDQGIW 1897
L G I C W
Sbjct: 262 LDGSDTIVCDSNSTW 276
Score = 115 bits (287), Expect = 6e-25
Identities = 82/280 (29%), Positives = 124/280 (44%), Gaps = 23/280 (8%)
Query: 1190 LPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLH--CTPQGDWS 1247
L S S C+ PP E + + G+ V Y C+ GY + H C W
Sbjct: 28 LYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWL 87
Query: 1248 PEAPRCAVKSCDDFLGQLPHGRVLFPLN--LQLGAKVSFVCDEGFRLKGSSVSHCVLVGM 1305
P + + ++ +G+ + P N + G ++ F+C+EG+ L G + +C L G
Sbjct: 88 PVSDDACYRETCPYIRDPLNGQAV-PANGTYEFGYQMHFICNEGYYLIGEEILYCELKGS 146
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
++W+ P+CE + C PP I NG+HT + Y ++Y+CDP P F+LIGE
Sbjct: 147 VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPD-PFSLIGE 205
Query: 1366 STIRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDF--EFPVGTSLN 1423
STI C N VWS AP C++ C+ FP I+ F +F ++
Sbjct: 206 STIYCGD----NSVWSRAAPECKVV----KCR----FPVVENGKQISGFGKKFYYKATVM 253
Query: 1424 YECRPG-YFGKMFSISCLENLVWSSVEDNCRRKSCGPPPE 1462
+EC G Y +I C N W C + P PE
Sbjct: 254 FECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKGY--PKPE 291
Score = 110 bits (274), Expect = 2e-23
Identities = 70/243 (28%), Positives = 115/243 (47%), Gaps = 21/243 (8%)
Query: 1730 QLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTP 1789
++G +V + C +G+ A+H + S C + CP LNG+
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1790 FGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGN-GVWSSPAPRCELSVPAAC 1848
G +G ++ + C+ + LIGE + C + +G+ +WS P CE C
Sbjct: 115 -GTYEFGYQMHFICNEG------YYLIGEEILYC--ELKGSVAIWSGKPPICE---KVLC 162
Query: 1849 PHPPKIQNGHYIGGHVSLYLPGMTISYICDPG-----YLLVGKGFIFCTDQGIWSQLDHY 1903
PPKI+NG + V ++ ++Y CDP + L+G+ I+C D +WS+
Sbjct: 163 TPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPE 222
Query: 1904 CKEVNCSFPLFMNGISKELE-MKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADDRWDPPL 1962
CK V C FP+ NG K++ K ++Y V +C+ G+ L+GS C ++ WDPP+
Sbjct: 223 CKVVKCRFPVVENG--KQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPV 280
Query: 1963 AKC 1965
KC
Sbjct: 281 PKC 283
Score = 87.8 bits (216), Expect = 1e-16
Identities = 58/237 (24%), Positives = 90/237 (37%), Gaps = 13/237 (5%)
Query: 1022 QVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTN 1081
++G R++Y C G+ I + I N C R C NG + N
Sbjct: 55 EIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPAN 114
Query: 1082 RENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPP 1141
+ +G + + CN G + L+GE +YC V IWSG P C PP
Sbjct: 115 G-TYEFGYQMHFICNEG------YYLIGEEILYCELKGS-VAIWSGKPPICEKVLCTPPP 166
Query: 1142 NVENGILVSDNRSLFSLNEVVEFRCQPG-----FVMKGPRRVKCQALNKWEPELPSCSRV 1196
++NG +F + V + C P F + G + C + W P C V
Sbjct: 167 KIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVV 226
Query: 1197 CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRC 1253
P + +G+ F V + C+ G+ L G+ ++ C W P P+C
Sbjct: 227 KCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKC 283
Score = 85.1 bits (209), Expect = 6e-16
Identities = 64/260 (24%), Positives = 98/260 (37%), Gaps = 19/260 (7%)
Query: 1456 SCGPPPEPFNGMVHINTDTQF---GSTVNYSCNEGFRLIGSPSTTCLVSGNNVTW-DKKA 1511
+C PP F M I + G V+Y C +G+ I P T + N TW
Sbjct: 34 ACEEPPT-FEAMELIGKPKPYYEIGERVDYKCKKGYFYI-PPLATHTICDRNHTWLPVSD 91
Query: 1512 PICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSK 1571
C +C NG N T + G + + C+ G + L+GE +YC K
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGT-YEFGYQMHFICNEG------YYLIGEEILYCELK 144
Query: 1572 DDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPG-----FVMV 1626
V +WS PP C P+++N F + + + C P F ++
Sbjct: 145 GS-VAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1627 GSHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLR 1686
G T+ C N W P C V P + +G+ F V + C+ + L
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLD 263
Query: 1687 GAASLHCTPQGDWSPEAPRC 1706
G+ ++ C W P P+C
Sbjct: 264 GSDTIVCDSNSTWDPPVPKC 283
Score = 84.7 bits (208), Expect = 8e-16
Identities = 72/265 (27%), Positives = 108/265 (40%), Gaps = 30/265 (11%)
Query: 1066 CGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEPSIYCTSNDDQVGIW 1125
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 1126 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 1181
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 1182 --ALNKWEPELPSCSRV-CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPG-----YDLR 1233
++ W + P C +V C PPP+I +G+HT S + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 1234 GAASLHCTPQGDWSPEAPRCAVKSCDDFLGQLPHGRVL--FPLNLQLGAKVSFVCDEGFR 1291
G ++++C WS AP C V C + +G+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 1292 LKGSSVSHCVLVGMRSLWNNSVPVC 1316
L GS C S W+ VP C
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKC 283
Score = 80.1 bits (196), Expect = 2e-14
Identities = 70/265 (26%), Positives = 106/265 (40%), Gaps = 30/265 (11%)
Query: 616 CGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIW 675
C PPT + I + + G V Y+C G F + P + + D+ W
Sbjct: 35 CEEPPTFEAMELIGKPKPYYEIGERVDYKCKKG-----YFYI---PPLATHTICDRNHTW 86
Query: 676 SGPAPQCIIPNKCTPPNVE---NGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQ- 731
+ C P + NG V N + + F C G+ + G + C+
Sbjct: 87 LPVSDDACYRETC--PYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCEL 143
Query: 732 --ALNKWEPELPSCSRV-CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPG-----YDLR 783
++ W + P C +V C PPP + + + T + + F V YSC+P + L
Sbjct: 144 KGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLI 203
Query: 784 GAASMRCTPQGDWSPAAPTCEVKSCDDFMGQLLNGRVL--FPVNLQLGAKVDFVCDEGFQ 841
G +++ C WS AAP C+V C + NG+ + F A V F CD+GF
Sbjct: 204 GESTIYCGDNSVWSRAAPECKVVKCR--FPVVENGKQISGFGKKFYYKATVMFECDKGFY 261
Query: 842 LKGSSASYCVLAGMESLWNSSVPVC 866
L GS C S W+ VP C
Sbjct: 262 LDGSDTIVC---DSNSTWDPPVPKC 283
Score = 73.2 bits (178), Expect = 2e-12
Identities = 66/262 (25%), Positives = 108/262 (41%), Gaps = 30/262 (11%)
Query: 1140 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGP--RRVKCQALNKWEP-ELPSCSR- 1195
PP E L+ + + + E V+++C+ G+ P C + W P +C R
Sbjct: 38 PPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRE 97
Query: 1196 VCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGD---WSPEAPR 1252
C + L+G+ P++ + G ++ + C GY L G L+C +G WS + P
Sbjct: 98 TCPYIRDPLNGQAVPAN-GTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPI 156
Query: 1253 CAVKSCDDFLGQLPHGRVLFP--LNLQLGAKVSFVCD-----EGFRLKGSSVSHCVLVGM 1305
C C ++ +G+ F + V++ CD + F L G S +C G
Sbjct: 157 CEKVLCTP-PPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC---GD 212
Query: 1306 RSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGE 1365
S+W+ + P C+ + C P + NG+ Y + + CD F L G
Sbjct: 213 NSVWSRAAPECKVVKC-RFPVVENGKQISGFGKKFYYKATVMFECD------KGFYLDGS 265
Query: 1366 STIRCTSDPHGNGVWSSPAPRC 1387
TI C S N W P P+C
Sbjct: 266 DTIVCDS----NSTWDPPVPKC 283
Score = 63.5 bits (153), Expect = 2e-09
Identities = 65/274 (23%), Positives = 112/274 (40%), Gaps = 33/274 (12%)
Query: 1588 TNKCTAPEVENAIRVPGN-RSFFTLTEIIRFRCQPGFVMV---GSHTVQCQTNGRWGPKL 1643
++ C P A+ + G + ++ + E + ++C+ G+ + +HT+ C N W P
Sbjct: 32 SDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTI-CDRNHTWLPVS 90
Query: 1644 PH-CSR-VCQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHCTPQGD--- 1698
C R C + L+G+ + + G ++ + C Y L G L+C +G
Sbjct: 91 DDACYRETCPYIRDPLNGQ-AVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAI 149
Query: 1699 WSPEAPRCTVKSCDD--FLGQLPHGRVLLPLNLQLGAKVSFVCD-----EGFRLKGRSAS 1751
WS + P C C + H + + L A V++ CD + F L G S
Sbjct: 150 WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDA-VTYSCDPAPGPDPFSLIGESTI 208
Query: 1752 HCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGM 1811
+C G ++W+ + P C+ + C P + NG+ +GK+ Y +
Sbjct: 209 YC---GDNSVWSRAAPECKVVKC-RFPVVENGKQISG------FGKKFYYKATVMFECDK 258
Query: 1812 TFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVP 1845
F L G +I C S N W P P+C P
Sbjct: 259 GFYLDGSDTIVCDS----NSTWDPPVPKCLKGYP 288
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.138 0.463
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 106,960,702
Number of Sequences: 37866
Number of extensions: 6101232
Number of successful extensions: 23711
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 81
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 12223
Number of HSP's gapped (non-prelim): 2886
length of query: 2039
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1921
effective length of database: 13,779,330
effective search space: 26470092930
effective search space used: 26470092930
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.