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Search of human proteins with 77812684
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|77812684 inorganic pyrophosphatase 2 isoform 5 precursor
[Homo sapiens]
(316 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|77812684 inorganic pyrophosphatase 2 isoform 5 precursor [Hom... 661 0.0
gi|29171702 inorganic pyrophosphatase 2 isoform 1 precursor [Hom... 650 0.0
gi|77812678 inorganic pyrophosphatase 2 isoform 2 precursor [Hom... 568 e-162
gi|11056044 pyrophosphatase 1 [Homo sapiens] 362 e-100
gi|77812680 inorganic pyrophosphatase 2 isoform 3 precursor [Hom... 330 1e-90
gi|77812682 inorganic pyrophosphatase 2 isoform 4 precursor [Hom... 246 2e-65
gi|57165424 cullin 4A isoform 1 [Homo sapiens] 30 2.1
gi|11140811 cullin 4A isoform 2 [Homo sapiens] 30 2.1
gi|221316749 carboxypeptidase A3 precursor [Homo sapiens] 30 2.8
gi|189217904 RPGRIP1-like isoform b [Homo sapiens] 29 4.8
gi|118442834 RPGRIP1-like isoform a [Homo sapiens] 29 4.8
gi|88501736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform ... 29 4.8
gi|27151736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform ... 29 4.8
gi|5032033 RNA binding motif protein 6 [Homo sapiens] 29 4.8
>gi|77812684 inorganic pyrophosphatase 2 isoform 5 precursor [Homo
sapiens]
Length = 316
Score = 661 bits (1705), Expect = 0.0
Identities = 316/316 (100%), Positives = 316/316 (100%)
Query: 1 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60
MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI
Sbjct: 1 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60
Query: 61 SPFHDIPLKVNSKEENGIPMKKARNDEYEIATKEPMNPIKQYVKDGKLRYVANIFPYKGY 120
SPFHDIPLKVNSKEENGIPMKKARNDEYEIATKEPMNPIKQYVKDGKLRYVANIFPYKGY
Sbjct: 61 SPFHDIPLKVNSKEENGIPMKKARNDEYEIATKEPMNPIKQYVKDGKLRYVANIFPYKGY 120
Query: 121 IWNYGTLPQTWEDPHEKDKSTNCFGDNDPIDVCEIGSKILSCGEVIHVKILGILALIDEG 180
IWNYGTLPQTWEDPHEKDKSTNCFGDNDPIDVCEIGSKILSCGEVIHVKILGILALIDEG
Sbjct: 121 IWNYGTLPQTWEDPHEKDKSTNCFGDNDPIDVCEIGSKILSCGEVIHVKILGILALIDEG 180
Query: 181 ETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEF 240
ETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEF
Sbjct: 181 ETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEF 240
Query: 241 KNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESVSSSP 300
KNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESVSSSP
Sbjct: 241 KNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESVSSSP 300
Query: 301 NKESNEEEQVWHFLGK 316
NKESNEEEQVWHFLGK
Sbjct: 301 NKESNEEEQVWHFLGK 316
>gi|29171702 inorganic pyrophosphatase 2 isoform 1 precursor [Homo
sapiens]
Length = 334
Score = 650 bits (1676), Expect = 0.0
Identities = 316/334 (94%), Positives = 316/334 (94%), Gaps = 18/334 (5%)
Query: 1 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60
MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI
Sbjct: 1 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60
Query: 61 SPFHDIPLKVNSKEENGIPMKKARNDEYE------------------IATKEPMNPIKQY 102
SPFHDIPLKVNSKEENGIPMKKARNDEYE IATKEPMNPIKQY
Sbjct: 61 SPFHDIPLKVNSKEENGIPMKKARNDEYENLFNMIVEIPRWTNAKMEIATKEPMNPIKQY 120
Query: 103 VKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNCFGDNDPIDVCEIGSKILSC 162
VKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNCFGDNDPIDVCEIGSKILSC
Sbjct: 121 VKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNCFGDNDPIDVCEIGSKILSC 180
Query: 163 GEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRL 222
GEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRL
Sbjct: 181 GEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRL 240
Query: 223 YKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPF 282
YKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPF
Sbjct: 241 YKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPF 300
Query: 283 RCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 316
RCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK
Sbjct: 301 RCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 334
>gi|77812678 inorganic pyrophosphatase 2 isoform 2 precursor [Homo
sapiens]
Length = 305
Score = 568 bits (1465), Expect = e-162
Identities = 287/334 (85%), Positives = 287/334 (85%), Gaps = 47/334 (14%)
Query: 1 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60
MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI
Sbjct: 1 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60
Query: 61 SPFHDIPLKVNSKEENGIPMKKARNDEYE------------------IATKEPMNPIKQY 102
SPFHDIPLKVNSKEENGIPMKKARNDEYE IATKEPMNPIKQY
Sbjct: 61 SPFHDIPLKVNSKEENGIPMKKARNDEYENLFNMIVEIPRWTNAKMEIATKEPMNPIKQY 120
Query: 103 VKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNCFGDNDPIDVCEIGSKILSC 162
VKDGKLRYVANIFPYKGYIWNYGTLPQ ILSC
Sbjct: 121 VKDGKLRYVANIFPYKGYIWNYGTLPQ-----------------------------ILSC 151
Query: 163 GEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRL 222
GEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRL
Sbjct: 152 GEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRL 211
Query: 223 YKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPF 282
YKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPF
Sbjct: 212 YKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPF 271
Query: 283 RCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 316
RCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK
Sbjct: 272 RCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 305
>gi|11056044 pyrophosphatase 1 [Homo sapiens]
Length = 289
Score = 362 bits (928), Expect = e-100
Identities = 166/266 (62%), Positives = 211/266 (79%), Gaps = 1/266 (0%)
Query: 32 MALYHTEERGQPCSQNYRLFFKNVTGHYISPFHDIPLKVNSKEENGI-PMKKARNDEYEI 90
M+ + TEER P S YR+F KN G YISPFHDIP+ + + + + + N + EI
Sbjct: 1 MSGFSTEERAAPFSLEYRVFLKNEKGQYISPFHDIPIYADKDVFHMVVEVPRWSNAKMEI 60
Query: 91 ATKEPMNPIKQYVKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNCFGDNDPI 150
ATK+P+NPIKQ VK GKLRYVAN+FPYKGYIWNYG +PQTWEDP DK T C GDNDPI
Sbjct: 61 ATKDPLNPIKQDVKKGKLRYVANLFPYKGYIWNYGAIPQTWEDPGHNDKHTGCCGDNDPI 120
Query: 151 DVCEIGSKILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKP 210
DVCEIGSK+ + GE+I VK+LGILA+IDEGETDWK+IAIN +DP+A+ ++DI+DVK+ KP
Sbjct: 121 DVCEIGSKVCARGEIIGVKVLGILAMIDEGETDWKVIAINVDDPDAANYNDINDVKRLKP 180
Query: 211 GYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAI 270
GYLEAT++WFR YKVPDGKPEN+FAFN EFK+K FA+++IKSTH WKAL+ KK NG I
Sbjct: 181 GYLEATVDWFRRYKVPDGKPENEFAFNAEFKDKDFAIDIIKSTHDHWKALVTKKTNGKGI 240
Query: 271 NCTNVQISDSPFRCTQEEARSLVESV 296
+C N +S+SPF+C + AR++V+++
Sbjct: 241 SCMNTTLSESPFKCDPDAARAIVDAL 266
>gi|77812680 inorganic pyrophosphatase 2 isoform 3 precursor [Homo
sapiens]
Length = 232
Score = 330 bits (845), Expect = 1e-90
Identities = 158/159 (99%), Positives = 159/159 (100%)
Query: 158 KILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATL 217
+ILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATL
Sbjct: 74 EILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATL 133
Query: 218 NWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQI 277
NWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQI
Sbjct: 134 NWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQI 193
Query: 278 SDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 316
SDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK
Sbjct: 194 SDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 232
Score = 153 bits (387), Expect = 2e-37
Identities = 74/74 (100%), Positives = 74/74 (100%)
Query: 1 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60
MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI
Sbjct: 1 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60
Query: 61 SPFHDIPLKVNSKE 74
SPFHDIPLKVNSKE
Sbjct: 61 SPFHDIPLKVNSKE 74
>gi|77812682 inorganic pyrophosphatase 2 isoform 4 precursor [Homo
sapiens]
Length = 168
Score = 246 bits (627), Expect = 2e-65
Identities = 116/118 (98%), Positives = 117/118 (99%)
Query: 199 FHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWK 258
F +IDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWK
Sbjct: 51 FFNIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWK 110
Query: 259 ALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 316
ALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK
Sbjct: 111 ALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 168
Score = 107 bits (267), Expect = 1e-23
Identities = 52/52 (100%), Positives = 52/52 (100%)
Query: 1 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFF 52
MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFF
Sbjct: 1 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFF 52
>gi|57165424 cullin 4A isoform 1 [Homo sapiens]
Length = 759
Score = 30.4 bits (67), Expect = 2.1
Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 9/73 (12%)
Query: 186 LIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFR------LYKVPDGKPE---NQFAF 236
L+ + N+ + F +I + L TL L K P GK ++F F
Sbjct: 597 LVLLMFNEGDGFSFEEIKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIF 656
Query: 237 NGEFKNKAFALEV 249
NGEFK+K F +++
Sbjct: 657 NGEFKHKLFRIKI 669
>gi|11140811 cullin 4A isoform 2 [Homo sapiens]
Length = 659
Score = 30.4 bits (67), Expect = 2.1
Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 9/73 (12%)
Query: 186 LIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFR------LYKVPDGKPE---NQFAF 236
L+ + N+ + F +I + L TL L K P GK ++F F
Sbjct: 497 LVLLMFNEGDGFSFEEIKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIF 556
Query: 237 NGEFKNKAFALEV 249
NGEFK+K F +++
Sbjct: 557 NGEFKHKLFRIKI 569
>gi|221316749 carboxypeptidase A3 precursor [Homo sapiens]
Length = 417
Score = 30.0 bits (66), Expect = 2.8
Identities = 15/58 (25%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Query: 88 YEIATKEPMNPIKQYVKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNCFG 145
Y+ N I + D Y+ +F GYIW++ T + W K++++ C G
Sbjct: 191 YQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSW-TKNRMWRKNRSKNQNSKCIG 247
>gi|189217904 RPGRIP1-like isoform b [Homo sapiens]
Length = 1235
Score = 29.3 bits (64), Expect = 4.8
Identities = 19/74 (25%), Positives = 35/74 (47%)
Query: 54 NVTGHYISPFHDIPLKVNSKEENGIPMKKARNDEYEIATKEPMNPIKQYVKDGKLRYVAN 113
N T Y+ +D+ L+ K + + +A + EYE + + K G++ A+
Sbjct: 656 NFTSQYLVHVNDLFLQYIQKNTITLEVHQAYSTEYETIAACQLKFHEILEKSGRIFCTAS 715
Query: 114 IFPYKGYIWNYGTL 127
+ KG I N+GT+
Sbjct: 716 LIGTKGDIPNFGTV 729
>gi|118442834 RPGRIP1-like isoform a [Homo sapiens]
Length = 1315
Score = 29.3 bits (64), Expect = 4.8
Identities = 19/74 (25%), Positives = 35/74 (47%)
Query: 54 NVTGHYISPFHDIPLKVNSKEENGIPMKKARNDEYEIATKEPMNPIKQYVKDGKLRYVAN 113
N T Y+ +D+ L+ K + + +A + EYE + + K G++ A+
Sbjct: 656 NFTSQYLVHVNDLFLQYIQKNTITLEVHQAYSTEYETIAACQLKFHEILEKSGRIFCTAS 715
Query: 114 IFPYKGYIWNYGTL 127
+ KG I N+GT+
Sbjct: 716 LIGTKGDIPNFGTV 729
>gi|88501736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform a
[Homo sapiens]
Length = 277
Score = 29.3 bits (64), Expect = 4.8
Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 8/53 (15%)
Query: 203 DDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQ 255
DD+KK Y L W PD P+N+ +FK A A EV+ H+
Sbjct: 17 DDIKK---AYRRKALQWH-----PDKNPDNKEFAEKKFKEVAEAYEVLSDKHK 61
>gi|27151736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform b
[Homo sapiens]
Length = 324
Score = 29.3 bits (64), Expect = 4.8
Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 8/53 (15%)
Query: 203 DDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQ 255
DD+KK Y L W PD P+N+ +FK A A EV+ H+
Sbjct: 17 DDIKK---AYRRKALQWH-----PDKNPDNKEFAEKKFKEVAEAYEVLSDKHK 61
>gi|5032033 RNA binding motif protein 6 [Homo sapiens]
Length = 1123
Score = 29.3 bits (64), Expect = 4.8
Identities = 20/78 (25%), Positives = 34/78 (43%), Gaps = 1/78 (1%)
Query: 27 GSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYISPFHDIPLKVNSKEENGIPMKKARND 86
G R + T +GQ S + ++ + TG+Y P N+++E +P +
Sbjct: 768 GGRNSDWSSDTNRQGQQSSSDCYIY-DSATGYYYDPLAGTYYDPNTQQEVYVPQDPGLPE 826
Query: 87 EYEIATKEPMNPIKQYVK 104
E EI K+P + K K
Sbjct: 827 EEEIKEKKPTSQGKSSSK 844
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,969,923
Number of Sequences: 37866
Number of extensions: 615740
Number of successful extensions: 1373
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1361
Number of HSP's gapped (non-prelim): 19
length of query: 316
length of database: 18,247,518
effective HSP length: 102
effective length of query: 214
effective length of database: 14,385,186
effective search space: 3078429804
effective search space used: 3078429804
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.