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Search of human proteins with 7706607
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7706607 LEM domain containing 3 [Homo sapiens]
(911 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7706607 LEM domain containing 3 [Homo sapiens] 1841 0.0
gi|31044432 LEM domain containing 2 isoform 1 [Homo sapiens] 192 9e-49
gi|221139815 LEM domain containing 2 isoform 2 [Homo sapiens] 171 2e-42
gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens] 102 2e-21
gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens] 102 2e-21
gi|73760401 thymopoietin isoform gamma [Homo sapiens] 49 2e-05
gi|73760405 thymopoietin isoform beta [Homo sapiens] 49 2e-05
gi|4507555 thymopoietin isoform alpha [Homo sapiens] 49 2e-05
gi|133922582 zinc finger protein 358 [Homo sapiens] 44 7e-04
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 42 0.002
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 42 0.002
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 42 0.002
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 42 0.002
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 42 0.003
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 42 0.003
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 42 0.003
gi|24308326 BR serine/threonine kinase 1 [Homo sapiens] 41 0.004
gi|148612857 sickle tail isoform 3 [Homo sapiens] 41 0.006
gi|148612813 sickle tail isoform 2 [Homo sapiens] 41 0.006
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 40 0.008
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 40 0.008
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 40 0.008
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 40 0.013
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 39 0.017
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] 39 0.017
gi|28467003 kinase interacting stathmin [Homo sapiens] 39 0.022
gi|56676324 LEM domain containing 1 [Homo sapiens] 39 0.022
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 39 0.029
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 39 0.029
gi|7706435 headcase [Homo sapiens] 39 0.029
>gi|7706607 LEM domain containing 3 [Homo sapiens]
Length = 911
Score = 1841 bits (4769), Expect = 0.0
Identities = 911/911 (100%), Positives = 911/911 (100%)
Query: 1 MAAAAASAPQQLSDEELFSQLRRYGLSPGPVTESTRPVYLKKLKKLREEEQQQHRSGGRG 60
MAAAAASAPQQLSDEELFSQLRRYGLSPGPVTESTRPVYLKKLKKLREEEQQQHRSGGRG
Sbjct: 1 MAAAAASAPQQLSDEELFSQLRRYGLSPGPVTESTRPVYLKKLKKLREEEQQQHRSGGRG 60
Query: 61 NKTRNSNNNNTAAATVAAAGPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPESLLG 120
NKTRNSNNNNTAAATVAAAGPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPESLLG
Sbjct: 61 NKTRNSNNNNTAAATVAAAGPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPESLLG 120
Query: 121 GPGGASAAPAAGSKVLLGFSSDESDVEASPRDQAGGGGRKDRASLQYRGLKAPPAPLAAS 180
GPGGASAAPAAGSKVLLGFSSDESDVEASPRDQAGGGGRKDRASLQYRGLKAPPAPLAAS
Sbjct: 121 GPGGASAAPAAGSKVLLGFSSDESDVEASPRDQAGGGGRKDRASLQYRGLKAPPAPLAAS 180
Query: 181 EVTNSNSAERRKPHSWWGARRPAGPELQTPPGKDGAVEDEEGEGEDGEERDPETEEPLWA 240
EVTNSNSAERRKPHSWWGARRPAGPELQTPPGKDGAVEDEEGEGEDGEERDPETEEPLWA
Sbjct: 181 EVTNSNSAERRKPHSWWGARRPAGPELQTPPGKDGAVEDEEGEGEDGEERDPETEEPLWA 240
Query: 241 SRTVNGSRLVPYSCRENYSDSEEEDDDDVASSRQVLKDDSLSRHRPRRTHSKPLPPLTAK 300
SRTVNGSRLVPYSCRENYSDSEEEDDDDVASSRQVLKDDSLSRHRPRRTHSKPLPPLTAK
Sbjct: 241 SRTVNGSRLVPYSCRENYSDSEEEDDDDVASSRQVLKDDSLSRHRPRRTHSKPLPPLTAK 300
Query: 301 SAGGRLETSVQGGGGLAMNDRAAAAGSLDRSRNLEEAAAAEQGGGCDQVDSSPVPRYRVN 360
SAGGRLETSVQGGGGLAMNDRAAAAGSLDRSRNLEEAAAAEQGGGCDQVDSSPVPRYRVN
Sbjct: 301 SAGGRLETSVQGGGGLAMNDRAAAAGSLDRSRNLEEAAAAEQGGGCDQVDSSPVPRYRVN 360
Query: 361 AKKLTPLLPPPLTDMDSTLDSSTGSLLKTNNHIGGGAFSVDSPRIYSNSLPPSAAVAASS 420
AKKLTPLLPPPLTDMDSTLDSSTGSLLKTNNHIGGGAFSVDSPRIYSNSLPPSAAVAASS
Sbjct: 361 AKKLTPLLPPPLTDMDSTLDSSTGSLLKTNNHIGGGAFSVDSPRIYSNSLPPSAAVAASS 420
Query: 421 SLRINHANHTGSNHTYLKNTYNKPKLSEPEEELLQQFKREEVSPTGSFSAHYLSMFLLTA 480
SLRINHANHTGSNHTYLKNTYNKPKLSEPEEELLQQFKREEVSPTGSFSAHYLSMFLLTA
Sbjct: 421 SLRINHANHTGSNHTYLKNTYNKPKLSEPEEELLQQFKREEVSPTGSFSAHYLSMFLLTA 480
Query: 481 ACLFFLILGLTYLGMRGTGVSEDGELSIENPFGETFGKIQESEKTLMMNTLYKLHDRLAQ 540
ACLFFLILGLTYLGMRGTGVSEDGELSIENPFGETFGKIQESEKTLMMNTLYKLHDRLAQ
Sbjct: 481 ACLFFLILGLTYLGMRGTGVSEDGELSIENPFGETFGKIQESEKTLMMNTLYKLHDRLAQ 540
Query: 541 LAGDHECGSSSQRTLSVQEAAAYLKDLGPEYEGIFNTSLQWILENGKDVGIRCVGFGPEE 600
LAGDHECGSSSQRTLSVQEAAAYLKDLGPEYEGIFNTSLQWILENGKDVGIRCVGFGPEE
Sbjct: 541 LAGDHECGSSSQRTLSVQEAAAYLKDLGPEYEGIFNTSLQWILENGKDVGIRCVGFGPEE 600
Query: 601 ELTNITDVQFLQSTRPLMSFWCRFRRAFVTVTHRLLLLCLGVVMVCVVLRYMKYRWTKEE 660
ELTNITDVQFLQSTRPLMSFWCRFRRAFVTVTHRLLLLCLGVVMVCVVLRYMKYRWTKEE
Sbjct: 601 ELTNITDVQFLQSTRPLMSFWCRFRRAFVTVTHRLLLLCLGVVMVCVVLRYMKYRWTKEE 660
Query: 661 EETRQMYDMVVKIIDVLRSHNEACQENKDLQPYMPIPHVRDSLIQPHDRKKMKKVWDRAV 720
EETRQMYDMVVKIIDVLRSHNEACQENKDLQPYMPIPHVRDSLIQPHDRKKMKKVWDRAV
Sbjct: 661 EETRQMYDMVVKIIDVLRSHNEACQENKDLQPYMPIPHVRDSLIQPHDRKKMKKVWDRAV 720
Query: 721 DFLAANESRVRTETRRIGGADFLVWRWIQPSASCDKILVIPSKVWQGQAFHLDRRNSPPN 780
DFLAANESRVRTETRRIGGADFLVWRWIQPSASCDKILVIPSKVWQGQAFHLDRRNSPPN
Sbjct: 721 DFLAANESRVRTETRRIGGADFLVWRWIQPSASCDKILVIPSKVWQGQAFHLDRRNSPPN 780
Query: 781 SLTPCLKIRNMFDPVMEIGDQWHLAIQEAILEKCSDNDGIVHIAVDKNSREGCVYVKCLS 840
SLTPCLKIRNMFDPVMEIGDQWHLAIQEAILEKCSDNDGIVHIAVDKNSREGCVYVKCLS
Sbjct: 781 SLTPCLKIRNMFDPVMEIGDQWHLAIQEAILEKCSDNDGIVHIAVDKNSREGCVYVKCLS 840
Query: 841 PEYAGKAFKALHGSWFDGKLVTVKYLRLDRYHHRFPQALTSNTPLKPSNKHMNSMSHLRL 900
PEYAGKAFKALHGSWFDGKLVTVKYLRLDRYHHRFPQALTSNTPLKPSNKHMNSMSHLRL
Sbjct: 841 PEYAGKAFKALHGSWFDGKLVTVKYLRLDRYHHRFPQALTSNTPLKPSNKHMNSMSHLRL 900
Query: 901 RTGLTNSQGSS 911
RTGLTNSQGSS
Sbjct: 901 RTGLTNSQGSS 911
>gi|31044432 LEM domain containing 2 isoform 1 [Homo sapiens]
Length = 503
Score = 192 bits (489), Expect = 9e-49
Identities = 109/292 (37%), Positives = 168/292 (57%), Gaps = 8/292 (2%)
Query: 472 YLSMFLLTAAC-LFFLILGLTYLGMRGTGVSEDGELSIE----NPFGETFGKIQESEKTL 526
+LS LL A+ L + LG+ ++ M ++ E +++ + +T Q +K
Sbjct: 209 WLSRLLLWASLGLLLVFLGILWVKMGKPSAPQEAEDNMKLLPVDCERKTDEFCQAKQKAA 268
Query: 527 MMNTLYKLHDRLAQLAGDHECGSSSQ---RTLSVQEAAAYLKDLGPEYEGIFNTSLQWIL 583
++ L++L++ LA AG+ ECG+ + + V EA Y+ ++ F +L WIL
Sbjct: 269 LLELLHELYNFLAIQAGNFECGNPENLKSKCIPVMEAQEYIANVTSSSSAKFEAALTWIL 328
Query: 584 ENGKDVGIRCVGFGPEEELTNITDVQFLQSTRPLMSFWCRFRRAFVTVTHRLLLLCLGVV 643
+ KDVGI G E +T + V L+S P M CR RA +T +L+ +
Sbjct: 329 SSNKDVGIWLKGEDQSELVTTVDKVVCLESAHPRMGVGCRLSRALLTAVTNVLIFFWCLA 388
Query: 644 MVCVVLRYMKYRWTKEEEETRQMYDMVVKIIDVLRSHNEACQENKDLQPYMPIPHVRDSL 703
+ +L +KYRW K EEE + MY+MV KIIDV++ H +++ + PY+ I HVRDSL
Sbjct: 389 FLWGLLILLKYRWRKLEEEEQAMYEMVKKIIDVVQDHYVDWEQDMERYPYVGILHVRDSL 448
Query: 704 IQPHDRKKMKKVWDRAVDFLAANESRVRTETRRIGGADFLVWRWIQPSASCD 755
I P R++MK+VWDRAV+FLA+NESR++TE+ R+ G D LVWRW +PS+ D
Sbjct: 449 IPPQSRRRMKRVWDRAVEFLASNESRIQTESHRVAGEDMLVWRWTKPSSFSD 500
Score = 52.0 bits (123), Expect = 3e-06
Identities = 51/154 (33%), Positives = 71/154 (46%), Gaps = 11/154 (7%)
Query: 12 LSDEELFSQLRRYGLSPGPVTESTRPVYLKKLK------KLREEEQQQHRSGGRGNKTRN 65
LSD EL +L+ G PGP+T++TR VY KL+ +LR+EE+ + + RG +
Sbjct: 4 LSDLELRRELQALGFQPGPITDTTRDVYRNKLRRLRGEARLRDEERLREEARPRGEERLR 63
Query: 66 SNNNNTAAATVAAAGPAAAAAAGMGV-RPVSGDLSYLRTPGGLCRISASGPESLLGGPGG 124
A + A AA+ A + +P SG S TPG I S S +G G
Sbjct: 64 EEARLREDAPLRARPAAASPRAEPWLSQPASG--SAYATPGAYGDIRPSA-ASWVGSRGL 120
Query: 125 A-SAAPAAGSKVLLGFSSDESDVEASPRDQAGGG 157
A A PA + S E D +A D+A G
Sbjct: 121 AYPARPAQLRRRASVRGSSEEDEDARTPDRATQG 154
>gi|221139815 LEM domain containing 2 isoform 2 [Homo sapiens]
Length = 201
Score = 171 bits (434), Expect = 2e-42
Identities = 86/197 (43%), Positives = 121/197 (61%)
Query: 559 EAAAYLKDLGPEYEGIFNTSLQWILENGKDVGIRCVGFGPEEELTNITDVQFLQSTRPLM 618
EA Y+ ++ F +L WIL + KDVGI G E +T + V L+S P M
Sbjct: 2 EAQEYIANVTSSSSAKFEAALTWILSSNKDVGIWLKGEDQSELVTTVDKVVCLESAHPRM 61
Query: 619 SFWCRFRRAFVTVTHRLLLLCLGVVMVCVVLRYMKYRWTKEEEETRQMYDMVVKIIDVLR 678
CR RA +T +L+ + + +L +KYRW K EEE + MY+MV KIIDV++
Sbjct: 62 GVGCRLSRALLTAVTNVLIFFWCLAFLWGLLILLKYRWRKLEEEEQAMYEMVKKIIDVVQ 121
Query: 679 SHNEACQENKDLQPYMPIPHVRDSLIQPHDRKKMKKVWDRAVDFLAANESRVRTETRRIG 738
H +++ + PY+ I HVRDSLI P R++MK+VWDRAV+FLA+NESR++TE+ R+
Sbjct: 122 DHYVDWEQDMERYPYVGILHVRDSLIPPQSRRRMKRVWDRAVEFLASNESRIQTESHRVA 181
Query: 739 GADFLVWRWIQPSASCD 755
G D LVWRW +PS+ D
Sbjct: 182 GEDMLVWRWTKPSSFSD 198
>gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens]
Length = 524
Score = 102 bits (253), Expect = 2e-21
Identities = 47/108 (43%), Positives = 68/108 (62%)
Query: 783 TPCLKIRNMFDPVMEIGDQWHLAIQEAILEKCSDNDGIVHIAVDKNSREGCVYVKCLSPE 842
T C ++ NMF+P E W I++ ++E+C+ + G++HI VDKNS +G VYVKC S
Sbjct: 417 TQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIA 476
Query: 843 YAGKAFKALHGSWFDGKLVTVKYLRLDRYHHRFPQALTSNTPLKPSNK 890
A A ALHG WF GK++T Y+ L YH+ FP ++T+ L PS +
Sbjct: 477 AAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR 524
>gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens]
Length = 530
Score = 102 bits (253), Expect = 2e-21
Identities = 47/108 (43%), Positives = 68/108 (62%)
Query: 783 TPCLKIRNMFDPVMEIGDQWHLAIQEAILEKCSDNDGIVHIAVDKNSREGCVYVKCLSPE 842
T C ++ NMF+P E W I++ ++E+C+ + G++HI VDKNS +G VYVKC S
Sbjct: 423 TQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIA 482
Query: 843 YAGKAFKALHGSWFDGKLVTVKYLRLDRYHHRFPQALTSNTPLKPSNK 890
A A ALHG WF GK++T Y+ L YH+ FP ++T+ L PS +
Sbjct: 483 AAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLVPSRR 530
>gi|73760401 thymopoietin isoform gamma [Homo sapiens]
Length = 345
Score = 48.9 bits (115), Expect = 2e-05
Identities = 24/67 (35%), Positives = 40/67 (59%), Gaps = 6/67 (8%)
Query: 11 QLSDEELFSQLRRYGLSPGPVTESTRPVYLKKLKKLREEEQQQHRS------GGRGNKTR 64
+L++E+L QL +YG++PGP+ +TR +Y KKL KLRE+ + S TR
Sbjct: 114 ELTNEDLLDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTR 173
Query: 65 NSNNNNT 71
+ +N++
Sbjct: 174 QNGSNDS 180
>gi|73760405 thymopoietin isoform beta [Homo sapiens]
Length = 454
Score = 48.9 bits (115), Expect = 2e-05
Identities = 24/67 (35%), Positives = 40/67 (59%), Gaps = 6/67 (8%)
Query: 11 QLSDEELFSQLRRYGLSPGPVTESTRPVYLKKLKKLREEEQQQHRS------GGRGNKTR 64
+L++E+L QL +YG++PGP+ +TR +Y KKL KLRE+ + S TR
Sbjct: 114 ELTNEDLLDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTR 173
Query: 65 NSNNNNT 71
+ +N++
Sbjct: 174 QNGSNDS 180
>gi|4507555 thymopoietin isoform alpha [Homo sapiens]
Length = 694
Score = 48.9 bits (115), Expect = 2e-05
Identities = 24/67 (35%), Positives = 40/67 (59%), Gaps = 6/67 (8%)
Query: 11 QLSDEELFSQLRRYGLSPGPVTESTRPVYLKKLKKLREEEQQQHRS------GGRGNKTR 64
+L++E+L QL +YG++PGP+ +TR +Y KKL KLRE+ + S TR
Sbjct: 114 ELTNEDLLDQLVKYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTISSSAENTR 173
Query: 65 NSNNNNT 71
+ +N++
Sbjct: 174 QNGSNDS 180
>gi|133922582 zinc finger protein 358 [Homo sapiens]
Length = 568
Score = 43.9 bits (102), Expect = 7e-04
Identities = 45/149 (30%), Positives = 65/149 (43%), Gaps = 34/149 (22%)
Query: 68 NNNTAAATVAAAGPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPE--SLLGGPGGA 125
+ AAA AAA AAAAAAG+G+ P S +R PG ++S GP+ S+LG G
Sbjct: 397 HEGAAAAAAAAAAAAAAAAAGLGLGPGLSPASMMR-PG---QVSLLGPDAVSVLGSGLGL 452
Query: 126 SAAPAAGSKVLLGFSSDESDVEASPRDQAGGGGRKDRASLQYRGLKAPPAPLAASEVTNS 185
S ++G +P +G G D +S G ++ P+P T
Sbjct: 453 SPGTSSG---------------RNPDPGSGPGTLPDPSSKPLPGSRSTPSP------TPV 491
Query: 186 NSAERRKPHSWWGARRPAGPELQTPPGKD 214
S++ + H AGP+L P D
Sbjct: 492 ESSDPKAGHD-------AGPDLVPSPDLD 513
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 42.4 bits (98), Expect = 0.002
Identities = 92/428 (21%), Positives = 135/428 (31%), Gaps = 112/428 (26%)
Query: 1 MAAAAASAPQQLSDEELFSQLRRYGLSPGPVTESTRPVYLKKLKKLREEEQQQHRSGGRG 60
++ + +S ++ ++ E R + V + P +K+ K E ++G G
Sbjct: 82 ISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETE-----KAGKTG 136
Query: 61 NKTRNSNNNNTAAATVAAAGPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPESLLG 120
N + T A ++ P +A VS G + A+
Sbjct: 137 NSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSET----EEEGSVPAFGAAAK----- 187
Query: 121 GPGGASAAPAAGSKVLLGFSSDESDVEASP-------------------RDQAGGGGRKD 161
PG SA A S SSDE+DVE P R A G+
Sbjct: 188 -PGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVG 246
Query: 162 RASLQYRGLKAPPAPLAASEVTNSNSAERRKPHSWWGARRPAGPELQ------------- 208
+ Q +G PPA A S S+E PAG Q
Sbjct: 247 DVTPQVKGGALPPAKRAKKPEEESESSEEGSESE---EEAPAGTRSQVKASEKILQVRAA 303
Query: 209 --------------TPPGKDGAVEDEEGEGEDGEERDPETEEPLWASRTVNGSRLVPYSC 254
PPGK GAV + G+ E+ + +EE
Sbjct: 304 SAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEES----------------- 346
Query: 255 RENYSDSEEEDDDDVA--------SSRQVLKDDSLSRHRPRRTHSKPLP----PLTAKSA 302
SDSEEE A + QV + ++ PR+ + P P AK+
Sbjct: 347 ----SDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQ 402
Query: 303 GGRLETSVQGGGGLAMNDRAAAAGSLDRSRNLEEA-AAAEQGGGCDQVDSSPVPRYRVNA 361
G+ E Q S + S + EEA A A+ G QV ++ P
Sbjct: 403 AGKREEDSQ--------------SSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPR 448
Query: 362 KKLTPLLP 369
K P P
Sbjct: 449 KGAAPAPP 456
Score = 35.0 bits (79), Expect = 0.32
Identities = 68/292 (23%), Positives = 109/292 (37%), Gaps = 37/292 (12%)
Query: 71 TAAATVAAAGPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPESLLG-GPGGASAAP 129
+A T++A G AAA R S +R P + A GP S+ G A+AA
Sbjct: 801 SAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN-STVLARGPASVPSVGKAVATAAQ 859
Query: 130 A-AGSKVLLGFSSDESDVEASPRDQAGGGGRKDRASLQYRGLKAPPAPLAASEVTNSNSA 188
A G + G S +ESD E A + + S + ++A AP S
Sbjct: 860 AQTGPEEDSGSSEEESDSEEEAETLA-----QVKPSGKTHQIRAALAPAKESP------- 907
Query: 189 ERRKPHSWWGARRPAGPELQTPPGKDGAVEDEEGE----GEDGEERDPETEEP--LWASR 242
R+ A P TPPGK G + G+ G EE D + E P + +++
Sbjct: 908 -----------RKGAAP---TPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ 953
Query: 243 TVNGSRLVPYSCRENYSDSEEEDDDDVASS-RQVLKDDSLSRHRPRRTHSKPLPPLT-AK 300
+ + R + AS+ R+ +S +R + + + P T
Sbjct: 954 VIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCL 1013
Query: 301 SAGGRLETSVQGGGGLAMNDRAAAAGSLDRSRNLEEAAAAEQGGGCDQVDSS 352
+ G R + +A+ AG+ + + +Q G QVDS+
Sbjct: 1014 TPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSA 1065
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 42.4 bits (98), Expect = 0.002
Identities = 92/428 (21%), Positives = 135/428 (31%), Gaps = 112/428 (26%)
Query: 1 MAAAAASAPQQLSDEELFSQLRRYGLSPGPVTESTRPVYLKKLKKLREEEQQQHRSGGRG 60
++ + +S ++ ++ E R + V + P +K+ K E ++G G
Sbjct: 82 ISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETE-----KAGKTG 136
Query: 61 NKTRNSNNNNTAAATVAAAGPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPESLLG 120
N + T A ++ P +A VS G + A+
Sbjct: 137 NSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSET----EEEGSVPAFGAAAK----- 187
Query: 121 GPGGASAAPAAGSKVLLGFSSDESDVEASP-------------------RDQAGGGGRKD 161
PG SA A S SSDE+DVE P R A G+
Sbjct: 188 -PGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVG 246
Query: 162 RASLQYRGLKAPPAPLAASEVTNSNSAERRKPHSWWGARRPAGPELQ------------- 208
+ Q +G PPA A S S+E PAG Q
Sbjct: 247 DVTPQVKGGALPPAKRAKKPEEESESSEEGSESE---EEAPAGTRSQVKASEKILQVRAA 303
Query: 209 --------------TPPGKDGAVEDEEGEGEDGEERDPETEEPLWASRTVNGSRLVPYSC 254
PPGK GAV + G+ E+ + +EE
Sbjct: 304 SAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEES----------------- 346
Query: 255 RENYSDSEEEDDDDVA--------SSRQVLKDDSLSRHRPRRTHSKPLP----PLTAKSA 302
SDSEEE A + QV + ++ PR+ + P P AK+
Sbjct: 347 ----SDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQ 402
Query: 303 GGRLETSVQGGGGLAMNDRAAAAGSLDRSRNLEEA-AAAEQGGGCDQVDSSPVPRYRVNA 361
G+ E Q S + S + EEA A A+ G QV ++ P
Sbjct: 403 AGKREEDSQ--------------SSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPR 448
Query: 362 KKLTPLLP 369
K P P
Sbjct: 449 KGAAPAPP 456
Score = 37.7 bits (86), Expect = 0.049
Identities = 80/338 (23%), Positives = 129/338 (38%), Gaps = 45/338 (13%)
Query: 71 TAAATVAAAGPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPESLLG-GPGGASAAP 129
+A T++A G AAA R S +R P + A GP S+ G A+AA
Sbjct: 801 SAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN-STVLARGPASVPSVGKAVATAAQ 859
Query: 130 A-AGSKVLLGFSSDESDVEASPRDQAGGGGRKDRASLQYRGLKAPPAPLAASEVTNSNSA 188
A G + G S +ESD E A + + S + ++A AP S
Sbjct: 860 AQTGPEEDSGSSEEESDSEEEAETLA-----QVKPSGKTHQIRAALAPAKESP------- 907
Query: 189 ERRKPHSWWGARRPAGPELQTPPGKDGAVEDEEGE----GEDGEERDPETEEP--LWASR 242
R+ A P TPPGK G + G+ G EE D + E P + +++
Sbjct: 908 -----------RKGAAP---TPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ 953
Query: 243 TVNGSRLVPYSCRENYSDSEEEDDDDVASS-RQVLKDDSLSRHRPRRTHSKPLPPLT-AK 300
+ + R + AS+ R+ +S +R + + + P T
Sbjct: 954 VIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCL 1013
Query: 301 SAGGRLETSVQGGGGLAMNDRAAAAGSLDRSRNLEEAAAAEQGGGCDQVD-----SSPVP 355
+ G R + +A+ AG+ + + +Q G QV S P+
Sbjct: 1014 TPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLT 1073
Query: 356 R--YRVNAKKLTPLLPP-PLTDMDSTLDSSTGSLLKTN 390
+ +V A+K + PP T S +DS+ G+L T+
Sbjct: 1074 QAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATS 1111
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
[Homo sapiens]
Length = 1450
Score = 42.4 bits (98), Expect = 0.002
Identities = 92/428 (21%), Positives = 135/428 (31%), Gaps = 112/428 (26%)
Query: 1 MAAAAASAPQQLSDEELFSQLRRYGLSPGPVTESTRPVYLKKLKKLREEEQQQHRSGGRG 60
++ + +S ++ ++ E R + V + P +K+ K E ++G G
Sbjct: 82 ISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETE-----KAGKTG 136
Query: 61 NKTRNSNNNNTAAATVAAAGPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPESLLG 120
N + T A ++ P +A VS G + A+
Sbjct: 137 NSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSET----EEEGSVPAFGAAAK----- 187
Query: 121 GPGGASAAPAAGSKVLLGFSSDESDVEASP-------------------RDQAGGGGRKD 161
PG SA A S SSDE+DVE P R A G+
Sbjct: 188 -PGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVG 246
Query: 162 RASLQYRGLKAPPAPLAASEVTNSNSAERRKPHSWWGARRPAGPELQ------------- 208
+ Q +G PPA A S S+E PAG Q
Sbjct: 247 DVTPQVKGGALPPAKRAKKPEEESESSEEGSESE---EEAPAGTRSQVKASEKILQVRAA 303
Query: 209 --------------TPPGKDGAVEDEEGEGEDGEERDPETEEPLWASRTVNGSRLVPYSC 254
PPGK GAV + G+ E+ + +EE
Sbjct: 304 SAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEES----------------- 346
Query: 255 RENYSDSEEEDDDDVA--------SSRQVLKDDSLSRHRPRRTHSKPLP----PLTAKSA 302
SDSEEE A + QV + ++ PR+ + P P AK+
Sbjct: 347 ----SDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQ 402
Query: 303 GGRLETSVQGGGGLAMNDRAAAAGSLDRSRNLEEA-AAAEQGGGCDQVDSSPVPRYRVNA 361
G+ E Q S + S + EEA A A+ G QV ++ P
Sbjct: 403 AGKREEDSQ--------------SSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPR 448
Query: 362 KKLTPLLP 369
K P P
Sbjct: 449 KGAAPAPP 456
Score = 35.0 bits (79), Expect = 0.32
Identities = 68/292 (23%), Positives = 109/292 (37%), Gaps = 37/292 (12%)
Query: 71 TAAATVAAAGPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPESLLG-GPGGASAAP 129
+A T++A G AAA R S +R P + A GP S+ G A+AA
Sbjct: 801 SAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN-STVLARGPASVPSVGKAVATAAQ 859
Query: 130 A-AGSKVLLGFSSDESDVEASPRDQAGGGGRKDRASLQYRGLKAPPAPLAASEVTNSNSA 188
A G + G S +ESD E A + + S + ++A AP S
Sbjct: 860 AQTGPEEDSGSSEEESDSEEEAETLA-----QVKPSGKTHQIRAALAPAKESP------- 907
Query: 189 ERRKPHSWWGARRPAGPELQTPPGKDGAVEDEEGE----GEDGEERDPETEEP--LWASR 242
R+ A P TPPGK G + G+ G EE D + E P + +++
Sbjct: 908 -----------RKGAAP---TPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQ 953
Query: 243 TVNGSRLVPYSCRENYSDSEEEDDDDVASS-RQVLKDDSLSRHRPRRTHSKPLPPLT-AK 300
+ + R + AS+ R+ +S +R + + + P T
Sbjct: 954 VIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCL 1013
Query: 301 SAGGRLETSVQGGGGLAMNDRAAAAGSLDRSRNLEEAAAAEQGGGCDQVDSS 352
+ G R + +A+ AG+ + + +Q G QVDS+
Sbjct: 1014 TPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSA 1065
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
[Homo sapiens]
Length = 958
Score = 42.4 bits (98), Expect = 0.002
Identities = 92/428 (21%), Positives = 135/428 (31%), Gaps = 112/428 (26%)
Query: 1 MAAAAASAPQQLSDEELFSQLRRYGLSPGPVTESTRPVYLKKLKKLREEEQQQHRSGGRG 60
++ + +S ++ ++ E R + V + P +K+ K E ++G G
Sbjct: 82 ISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETE-----KAGKTG 136
Query: 61 NKTRNSNNNNTAAATVAAAGPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPESLLG 120
N + T A ++ P +A VS G + A+
Sbjct: 137 NSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSET----EEEGSVPAFGAAAK----- 187
Query: 121 GPGGASAAPAAGSKVLLGFSSDESDVEASP-------------------RDQAGGGGRKD 161
PG SA A S SSDE+DVE P R A G+
Sbjct: 188 -PGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVG 246
Query: 162 RASLQYRGLKAPPAPLAASEVTNSNSAERRKPHSWWGARRPAGPELQ------------- 208
+ Q +G PPA A S S+E PAG Q
Sbjct: 247 DVTPQVKGGALPPAKRAKKPEEESESSEEGSESE---EEAPAGTRSQVKASEKILQVRAA 303
Query: 209 --------------TPPGKDGAVEDEEGEGEDGEERDPETEEPLWASRTVNGSRLVPYSC 254
PPGK GAV + G+ E+ + +EE
Sbjct: 304 SAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEES----------------- 346
Query: 255 RENYSDSEEEDDDDVA--------SSRQVLKDDSLSRHRPRRTHSKPLP----PLTAKSA 302
SDSEEE A + QV + ++ PR+ + P P AK+
Sbjct: 347 ----SDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQ 402
Query: 303 GGRLETSVQGGGGLAMNDRAAAAGSLDRSRNLEEA-AAAEQGGGCDQVDSSPVPRYRVNA 361
G+ E Q S + S + EEA A A+ G QV ++ P
Sbjct: 403 AGKREEDSQ--------------SSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPR 448
Query: 362 KKLTPLLP 369
K P P
Sbjct: 449 KGAAPAPP 456
Score = 33.9 bits (76), Expect = 0.71
Identities = 49/173 (28%), Positives = 67/173 (38%), Gaps = 33/173 (19%)
Query: 71 TAAATVAAAGPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPESLLG-GPGGASAAP 129
+A T++A G AAA R S +R P + A GP S+ G A+AA
Sbjct: 801 SAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQN-STVLARGPASVPSVGKAVATAAQ 859
Query: 130 A-AGSKVLLGFSSDESDVEASPRDQAGGGGRKDRASLQYRGLKAPPAPLAASEVTNSNSA 188
A G + G S +ESD E A + + S + ++A AP S
Sbjct: 860 AQTGPEEDSGSSEEESDSEEEAETLA-----QVKPSGKTHQIRAALAPAKESP------- 907
Query: 189 ERRKPHSWWGARRPAGPELQTPPGKDGAVEDEEGE----GEDGEERDPETEEP 237
R+ A P TPPGK G + G+ G EE D + E P
Sbjct: 908 -----------RKGAAP---TPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAP 946
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 41.6 bits (96), Expect = 0.003
Identities = 50/192 (26%), Positives = 67/192 (34%), Gaps = 31/192 (16%)
Query: 27 SPGPVTESTRPVYLKKLKKLREEEQQQHRSGGRGNKTRNSNNNNTAAATVAAAGPAAAAA 86
SPGPV+ R R G G K + T A A P +A
Sbjct: 110 SPGPVSSPGRA-------------SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSAL 156
Query: 87 AGMGVRPVSGDLSYLRTPGGLCRISASGPESLLGGPGGASAA--PAAGSKVLLGFSSDES 144
+ R SG +P R A+G E L P ++ P G + + +S+ S
Sbjct: 157 SAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS 216
Query: 145 DVEASP----RDQAGGGGRKDRASLQYRGLKAPPAPLAASEVTNSNSAERRKPHSWWGAR 200
E SP R AGGG L+ P + +S T +S R P + R
Sbjct: 217 TTEPSPAARRRPSAGGG------------LQRPASRSLSSSATPLSSPARSGPSARGTPR 264
Query: 201 RPAGPELQTPPG 212
PA P P G
Sbjct: 265 APAHPSQPKPKG 276
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 41.6 bits (96), Expect = 0.003
Identities = 50/192 (26%), Positives = 67/192 (34%), Gaps = 31/192 (16%)
Query: 27 SPGPVTESTRPVYLKKLKKLREEEQQQHRSGGRGNKTRNSNNNNTAAATVAAAGPAAAAA 86
SPGPV+ R R G G K + T A A P +A
Sbjct: 110 SPGPVSSPGRA-------------SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSAL 156
Query: 87 AGMGVRPVSGDLSYLRTPGGLCRISASGPESLLGGPGGASAA--PAAGSKVLLGFSSDES 144
+ R SG +P R A+G E L P ++ P G + + +S+ S
Sbjct: 157 SAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS 216
Query: 145 DVEASP----RDQAGGGGRKDRASLQYRGLKAPPAPLAASEVTNSNSAERRKPHSWWGAR 200
E SP R AGGG L+ P + +S T +S R P + R
Sbjct: 217 TTEPSPAARRRPSAGGG------------LQRPASRSLSSSATPLSSPARSGPSARGTPR 264
Query: 201 RPAGPELQTPPG 212
PA P P G
Sbjct: 265 APAHPSQPKPKG 276
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 41.6 bits (96), Expect = 0.003
Identities = 50/192 (26%), Positives = 67/192 (34%), Gaps = 31/192 (16%)
Query: 27 SPGPVTESTRPVYLKKLKKLREEEQQQHRSGGRGNKTRNSNNNNTAAATVAAAGPAAAAA 86
SPGPV+ R R G G K + T A A P +A
Sbjct: 101 SPGPVSSPGRA-------------SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSAL 147
Query: 87 AGMGVRPVSGDLSYLRTPGGLCRISASGPESLLGGPGGASAA--PAAGSKVLLGFSSDES 144
+ R SG +P R A+G E L P ++ P G + + +S+ S
Sbjct: 148 SAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS 207
Query: 145 DVEASP----RDQAGGGGRKDRASLQYRGLKAPPAPLAASEVTNSNSAERRKPHSWWGAR 200
E SP R AGGG L+ P + +S T +S R P + R
Sbjct: 208 TTEPSPAARRRPSAGGG------------LQRPASRSLSSSATPLSSPARSGPSARGTPR 255
Query: 201 RPAGPELQTPPG 212
PA P P G
Sbjct: 256 APAHPSQPKPKG 267
>gi|24308326 BR serine/threonine kinase 1 [Homo sapiens]
Length = 778
Score = 41.2 bits (95), Expect = 0.004
Identities = 63/266 (23%), Positives = 95/266 (35%), Gaps = 39/266 (14%)
Query: 187 SAERRKPHSWW-GARRPAGPELQTPPGKDGAVEDEEGEGEDGEE-----------RDPET 234
S E+ + H W+ G + P L+ PG+ A+ GE + RD E
Sbjct: 275 SLEQIQKHPWYLGGKHEPDPCLEPAPGRRVAMRSLPSNGELDPDVLESMASLGCFRDRER 334
Query: 235 EEPLWASRTVNGSRLVPYSC---RENYSDSEEED---DDDVASSRQVLKDDSLSRHRPRR 288
S N +++ Y +E Y E++D +DV R+ + LSRH RR
Sbjct: 335 LHRELRSEEENQEKMIYYLLLDRKERYPSCEDQDLPPRNDVDPPRKRVDSPMLSRHGKRR 394
Query: 289 THSKPLPPLTAKSAGGRLETSVQGGGGLAMNDRAAAAGSLDRSRNLEEAAAAEQGGGCDQ 348
K + L+ AGG GG + A RSR++ A+
Sbjct: 395 PERKSMEVLSITDAGG-------GGSPVPTRRALEMAQHSQRSRSVSGASTG-------- 439
Query: 349 VDSSPVPRYRVNAKKLTPLLPPPLTDM---DSTLDSSTGSLLKTNNHIGGGAFSVDSPRI 405
+ SSP+ R +P P D + S T +L GG P
Sbjct: 440 LSSSPLSSPRSPVFSFSP--EPGAGDEARGGGSPTSKTQTLPSRGPRGGGAGEQPPPPSA 497
Query: 406 YSNSLP-PSAAVAASSSLRINHANHT 430
S LP P + +S ++ HT
Sbjct: 498 RSTPLPGPPGSPRSSGGTPLHSPLHT 523
>gi|148612857 sickle tail isoform 3 [Homo sapiens]
Length = 1309
Score = 40.8 bits (94), Expect = 0.006
Identities = 102/450 (22%), Positives = 163/450 (36%), Gaps = 82/450 (18%)
Query: 7 SAPQQLSDEELFSQLRRYGLSPGPVTESTRPVYLKKLKKLREEEQQQ--HRSGGRGNKTR 64
SA Q L EE+ S V+ R V ++K +K EE++Q H +G K
Sbjct: 908 SAMQSLFIEEIHS-----------VSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLL 956
Query: 65 NSNNNNTAAATVAAAGPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPES-----LL 119
A A + + P + + P +G L P +S P S L
Sbjct: 957 EE-----AQANIMKSIP------NLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKL 1005
Query: 120 GGPGGASAAPAAGSKVLLGFSSDESDVEASPRDQAGGGGRKDRASLQYRGLKAPPAPLAA 179
GG P L G S + + GRK+ + + A P+P
Sbjct: 1006 GGKSPPPPPPPPRRSYLPG-----SGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQ-- 1058
Query: 180 SEVTNSNSAERRKPHSWWGARRPAGPELQTPPGKDGAVEDEEGEGEDGEERDPETEEPLW 239
T + +P S W P+ P + T KD EE E E+G++ E +
Sbjct: 1059 ---TRATKYPAEEPASAW---TPSPPPVTTSSSKD-----EEEEEEEGDKIMAELQGSSG 1107
Query: 240 ASRTVNGSRL-VPYSCRENYSDSEEEDDDDVASSRQVLKDDSLSRHRPRRTHSKPLPPLT 298
A +T SR+ VP S + ++ K L R R + +
Sbjct: 1108 APQT---SRMPVPMSAKNRPGTLDKPG-----------KQSKLQDPRQYRQANG-----S 1148
Query: 299 AKSAGGRLETSVQGGGGLAMNDRAAAAGSLDRSRNLEEAAAAEQGGGCDQVDSSPVPRYR 358
AK +GG + + L + A + S +S +L ++ G + + P +
Sbjct: 1149 AKKSGGDFKPT---SPSLPASKIPALSPSSGKSSSLPSSS-----GDSSNLPNPPATKPS 1200
Query: 359 VNAKKLTPLLPPPLTDMDSTLDSSTGSL-LKTNNHIGGGAFSVDSPRIYSNSLPPSAAVA 417
+ + L+P PP S GSL ++ H G G SP+ + PP + +
Sbjct: 1201 IASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFS 1260
Query: 418 AS-----SSLRINH-ANHTGSNHTYLKNTY 441
+S SS+ +N A T + HT +Y
Sbjct: 1261 SSPPSPASSVSLNQGAKGTRTIHTPSLTSY 1290
>gi|148612813 sickle tail isoform 2 [Homo sapiens]
Length = 1264
Score = 40.8 bits (94), Expect = 0.006
Identities = 102/450 (22%), Positives = 163/450 (36%), Gaps = 82/450 (18%)
Query: 7 SAPQQLSDEELFSQLRRYGLSPGPVTESTRPVYLKKLKKLREEEQQQ--HRSGGRGNKTR 64
SA Q L EE+ S V+ R V ++K +K EE++Q H +G K
Sbjct: 863 SAMQSLFIEEIHS-----------VSAKNRAVSIEKAEKKWEEKRQNLDHYNGKEFEKLL 911
Query: 65 NSNNNNTAAATVAAAGPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPES-----LL 119
A A + + P + + P +G L P +S P S L
Sbjct: 912 EE-----AQANIMKSIP------NLEMPPATGPLPRGDAPVDKVELSEDSPNSEQDLEKL 960
Query: 120 GGPGGASAAPAAGSKVLLGFSSDESDVEASPRDQAGGGGRKDRASLQYRGLKAPPAPLAA 179
GG P L G S + + GRK+ + + A P+P
Sbjct: 961 GGKSPPPPPPPPRRSYLPG-----SGLTTTRSGDVVYTGRKENITAKASSEDAGPSPQ-- 1013
Query: 180 SEVTNSNSAERRKPHSWWGARRPAGPELQTPPGKDGAVEDEEGEGEDGEERDPETEEPLW 239
T + +P S W P+ P + T KD EE E E+G++ E +
Sbjct: 1014 ---TRATKYPAEEPASAW---TPSPPPVTTSSSKD-----EEEEEEEGDKIMAELQGSSG 1062
Query: 240 ASRTVNGSRL-VPYSCRENYSDSEEEDDDDVASSRQVLKDDSLSRHRPRRTHSKPLPPLT 298
A +T SR+ VP S + ++ K L R R + +
Sbjct: 1063 APQT---SRMPVPMSAKNRPGTLDKPG-----------KQSKLQDPRQYRQANG-----S 1103
Query: 299 AKSAGGRLETSVQGGGGLAMNDRAAAAGSLDRSRNLEEAAAAEQGGGCDQVDSSPVPRYR 358
AK +GG + + L + A + S +S +L ++ G + + P +
Sbjct: 1104 AKKSGGDFKPT---SPSLPASKIPALSPSSGKSSSLPSSS-----GDSSNLPNPPATKPS 1155
Query: 359 VNAKKLTPLLPPPLTDMDSTLDSSTGSL-LKTNNHIGGGAFSVDSPRIYSNSLPPSAAVA 417
+ + L+P PP S GSL ++ H G G SP+ + PP + +
Sbjct: 1156 IASNPLSPQTGPPAHSASLIPSVSNGSLKFQSLTHTGKGHHLSFSPQSQNGRAPPPLSFS 1215
Query: 418 AS-----SSLRINH-ANHTGSNHTYLKNTY 441
+S SS+ +N A T + HT +Y
Sbjct: 1216 SSPPSPASSVSLNQGAKGTRTIHTPSLTSY 1245
>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
sapiens]
Length = 1818
Score = 40.4 bits (93), Expect = 0.008
Identities = 47/168 (27%), Positives = 59/168 (35%), Gaps = 25/168 (14%)
Query: 76 VAAAGPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPESLLGGPGGASAAPAAGSKV 135
V GPA A G GD + PG + + G + G PG G+
Sbjct: 1122 VGLPGPAGPA----GSPGEDGDKGEIGEPG---QKGSKGDKGENGPPGPPGLQGPVGAPG 1174
Query: 136 LLGFSSDESDVEASPRDQAGGGGRKDRASLQYRGLKAPPAPLAAS-------EVTNSNSA 188
+ G D E PR Q G G+K RG PP P+ E +
Sbjct: 1175 IAG-----GDGEPGPRGQQGMFGQKGDEGA--RGFPGPPGPIGLQGLPGPPGEKGENGDV 1227
Query: 189 ERRKPHSWWGARRPAGPE----LQTPPGKDGAVEDEEGEGEDGEERDP 232
P G R P GP Q PPG G+V +GE GE +P
Sbjct: 1228 GPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNP 1275
Score = 35.0 bits (79), Expect = 0.32
Identities = 39/148 (26%), Positives = 47/148 (31%), Gaps = 18/148 (12%)
Query: 80 GPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPESLLGGPGGASAAPAAGSKVLLGF 139
GPA G G + GD PG GP G PG A A G K G
Sbjct: 1336 GPAGQDGVG-GDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKG- 1393
Query: 140 SSDESDVEASPRDQAGGGGRKDRASLQYRGLKAPPAPLAASEVTNSNSAERRKPHSWWGA 199
E+ E P G + GL+ P P+ + + G
Sbjct: 1394 ---EAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAA-----------GQ 1439
Query: 200 RRPAGPELQTPPGKDGAVEDEEGEGEDG 227
P GP PPG G D +GE G
Sbjct: 1440 DGPPGP--MGPPGLPGLKGDPGSKGEKG 1465
Score = 32.7 bits (73), Expect = 1.6
Identities = 40/137 (29%), Positives = 49/137 (35%), Gaps = 16/137 (11%)
Query: 95 SGDLSYLRTPGGLCRISASGPESLLGGPGGASAAPAAGSKVLLGFSSDESDVEASPRDQA 154
+G+ L PG GP+ G PG A G++ + G + PR Q
Sbjct: 843 AGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAG--------KPGPRGQR 894
Query: 155 GGGGRKDRASLQYRGLKAPPAPLAAS--EVTNSNSAER--RKPHSWWGARRPAGPELQTP 210
G G R S RG P P S + ER + P G P GP P
Sbjct: 895 GPTG--PRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPP--GP 950
Query: 211 PGKDGAVEDEEGEGEDG 227
PGKDG GE G
Sbjct: 951 PGKDGLPGHPGQRGETG 967
Score = 30.4 bits (67), Expect = 7.8
Identities = 33/117 (28%), Positives = 40/117 (34%), Gaps = 12/117 (10%)
Query: 114 GPESLLGGPGGASAAPAAGSKVLLGFSSDESD--VEASPRDQAGGGGRKDRASLQYRGLK 171
GP L G PG ++G+K G + V+ P G R + RG+
Sbjct: 544 GPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMP 603
Query: 172 APPAPLAASEVTNSNSAERRKPHSWWGARRPAGPELQTPPGKDGAVEDEEGEGEDGE 228
P K H G R P GP PPG DG GEDGE
Sbjct: 604 GEPGAKGDRGFDGLPGLPGDKGHR--GERGPQGPP--GPPGDDGM------RGEDGE 650
>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
sapiens]
Length = 1767
Score = 40.4 bits (93), Expect = 0.008
Identities = 47/168 (27%), Positives = 59/168 (35%), Gaps = 25/168 (14%)
Query: 76 VAAAGPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPESLLGGPGGASAAPAAGSKV 135
V GPA A G GD + PG + + G + G PG G+
Sbjct: 1071 VGLPGPAGPA----GSPGEDGDKGEIGEPG---QKGSKGDKGENGPPGPPGLQGPVGAPG 1123
Query: 136 LLGFSSDESDVEASPRDQAGGGGRKDRASLQYRGLKAPPAPLAAS-------EVTNSNSA 188
+ G D E PR Q G G+K RG PP P+ E +
Sbjct: 1124 IAG-----GDGEPGPRGQQGMFGQKGDEGA--RGFPGPPGPIGLQGLPGPPGEKGENGDV 1176
Query: 189 ERRKPHSWWGARRPAGPE----LQTPPGKDGAVEDEEGEGEDGEERDP 232
P G R P GP Q PPG G+V +GE GE +P
Sbjct: 1177 GPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNP 1224
Score = 35.0 bits (79), Expect = 0.32
Identities = 39/148 (26%), Positives = 47/148 (31%), Gaps = 18/148 (12%)
Query: 80 GPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPESLLGGPGGASAAPAAGSKVLLGF 139
GPA G G + GD PG GP G PG A A G K G
Sbjct: 1285 GPAGQDGVG-GDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKG- 1342
Query: 140 SSDESDVEASPRDQAGGGGRKDRASLQYRGLKAPPAPLAASEVTNSNSAERRKPHSWWGA 199
E+ E P G + GL+ P P+ + + G
Sbjct: 1343 ---EAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAA-----------GQ 1388
Query: 200 RRPAGPELQTPPGKDGAVEDEEGEGEDG 227
P GP PPG G D +GE G
Sbjct: 1389 DGPPGP--MGPPGLPGLKGDPGSKGEKG 1414
Score = 32.7 bits (73), Expect = 1.6
Identities = 40/137 (29%), Positives = 49/137 (35%), Gaps = 16/137 (11%)
Query: 95 SGDLSYLRTPGGLCRISASGPESLLGGPGGASAAPAAGSKVLLGFSSDESDVEASPRDQA 154
+G+ L PG GP+ G PG A G++ + G + PR Q
Sbjct: 792 AGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAG--------KPGPRGQR 843
Query: 155 GGGGRKDRASLQYRGLKAPPAPLAAS--EVTNSNSAER--RKPHSWWGARRPAGPELQTP 210
G G R S RG P P S + ER + P G P GP P
Sbjct: 844 GPTG--PRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPP--GP 899
Query: 211 PGKDGAVEDEEGEGEDG 227
PGKDG GE G
Sbjct: 900 PGKDGLPGHPGQRGETG 916
Score = 30.4 bits (67), Expect = 7.8
Identities = 33/117 (28%), Positives = 40/117 (34%), Gaps = 12/117 (10%)
Query: 114 GPESLLGGPGGASAAPAAGSKVLLGFSSDESD--VEASPRDQAGGGGRKDRASLQYRGLK 171
GP L G PG ++G+K G + V+ P G R + RG+
Sbjct: 493 GPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMP 552
Query: 172 APPAPLAASEVTNSNSAERRKPHSWWGARRPAGPELQTPPGKDGAVEDEEGEGEDGE 228
P K H G R P GP PPG DG GEDGE
Sbjct: 553 GEPGAKGDRGFDGLPGLPGDKGHR--GERGPQGPP--GPPGDDGM------RGEDGE 599
>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
sapiens]
Length = 1806
Score = 40.4 bits (93), Expect = 0.008
Identities = 47/168 (27%), Positives = 59/168 (35%), Gaps = 25/168 (14%)
Query: 76 VAAAGPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPESLLGGPGGASAAPAAGSKV 135
V GPA A G GD + PG + + G + G PG G+
Sbjct: 1110 VGLPGPAGPA----GSPGEDGDKGEIGEPG---QKGSKGDKGENGPPGPPGLQGPVGAPG 1162
Query: 136 LLGFSSDESDVEASPRDQAGGGGRKDRASLQYRGLKAPPAPLAAS-------EVTNSNSA 188
+ G D E PR Q G G+K RG PP P+ E +
Sbjct: 1163 IAG-----GDGEPGPRGQQGMFGQKGDEGA--RGFPGPPGPIGLQGLPGPPGEKGENGDV 1215
Query: 189 ERRKPHSWWGARRPAGPE----LQTPPGKDGAVEDEEGEGEDGEERDP 232
P G R P GP Q PPG G+V +GE GE +P
Sbjct: 1216 GPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNP 1263
Score = 35.0 bits (79), Expect = 0.32
Identities = 39/148 (26%), Positives = 47/148 (31%), Gaps = 18/148 (12%)
Query: 80 GPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPESLLGGPGGASAAPAAGSKVLLGF 139
GPA G G + GD PG GP G PG A A G K G
Sbjct: 1324 GPAGQDGVG-GDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKG- 1381
Query: 140 SSDESDVEASPRDQAGGGGRKDRASLQYRGLKAPPAPLAASEVTNSNSAERRKPHSWWGA 199
E+ E P G + GL+ P P+ + + G
Sbjct: 1382 ---EAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAA-----------GQ 1427
Query: 200 RRPAGPELQTPPGKDGAVEDEEGEGEDG 227
P GP PPG G D +GE G
Sbjct: 1428 DGPPGP--MGPPGLPGLKGDPGSKGEKG 1453
Score = 32.7 bits (73), Expect = 1.6
Identities = 40/137 (29%), Positives = 49/137 (35%), Gaps = 16/137 (11%)
Query: 95 SGDLSYLRTPGGLCRISASGPESLLGGPGGASAAPAAGSKVLLGFSSDESDVEASPRDQA 154
+G+ L PG GP+ G PG A G++ + G + PR Q
Sbjct: 831 AGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAG--------KPGPRGQR 882
Query: 155 GGGGRKDRASLQYRGLKAPPAPLAAS--EVTNSNSAER--RKPHSWWGARRPAGPELQTP 210
G G R S RG P P S + ER + P G P GP P
Sbjct: 883 GPTG--PRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPP--GP 938
Query: 211 PGKDGAVEDEEGEGEDG 227
PGKDG GE G
Sbjct: 939 PGKDGLPGHPGQRGETG 955
Score = 30.4 bits (67), Expect = 7.8
Identities = 33/117 (28%), Positives = 40/117 (34%), Gaps = 12/117 (10%)
Query: 114 GPESLLGGPGGASAAPAAGSKVLLGFSSDESD--VEASPRDQAGGGGRKDRASLQYRGLK 171
GP L G PG ++G+K G + V+ P G R + RG+
Sbjct: 532 GPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMP 591
Query: 172 APPAPLAASEVTNSNSAERRKPHSWWGARRPAGPELQTPPGKDGAVEDEEGEGEDGE 228
P K H G R P GP PPG DG GEDGE
Sbjct: 592 GEPGAKGDRGFDGLPGLPGDKGHR--GERGPQGPP--GPPGDDGM------RGEDGE 638
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
sapiens]
Length = 2524
Score = 39.7 bits (91), Expect = 0.013
Identities = 83/355 (23%), Positives = 122/355 (34%), Gaps = 55/355 (15%)
Query: 41 KKLKKLREEEQQQHRSGGRGNKTRNSNNNNTAAATVAAAGPAAAAAAGMGVRPVSGDLSY 100
KK + L E QQ + R AAA+ AA P M VSG+
Sbjct: 657 KKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEE 716
Query: 101 LRTPGGLCRISASGPESLLGGPGGASAAPAAGSKVLLGFSSDESDVEASPRDQA----GG 156
+ + ASG E P G + PA + +S +++ SP +A G
Sbjct: 717 MVEEAE--ALHASGNEV----PRGECSGPATVN------NSSDTESIPSPHTEAAKDTGQ 764
Query: 157 GGRKDRASLQYRG------------LKAPPAPLAASEVTNSNSAERRKPHSWWGARRPAG 204
G K A+L G + AP P ASE T + + PA
Sbjct: 765 NGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPP------------PAP 812
Query: 205 PELQTPPGKDGAVEDEEGEG-----EDGEERDPETEEPLWASRTVNGSRLVPYSCRENYS 259
P PP E EE E+GEE+ P E L A T V C E
Sbjct: 813 PSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEEL-AVDTGKAEEPVKSECTEEAE 871
Query: 260 DSEEEDDDDVASSRQVLKDDSLSRHRPRRTHSKPLPPLTAKSAGGRLETSVQGGGGLAMN 319
+ + D A + + + +L + + TAKS+G ++
Sbjct: 872 EGPAKGKD--AEAAEATAEGALKAEKKEGGSGR---ATTAKSSGAPQDSD---SSATCSA 923
Query: 320 DRAAAAGSLDRSRNLEEAAAAEQGGGCDQVDSSP-VPRYRVNAKKLTPLLPPPLT 373
D A D++R L + G + ++SP P K+ +PP +T
Sbjct: 924 DEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVT 978
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 39.3 bits (90), Expect = 0.017
Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 4/115 (3%)
Query: 217 VEDEEGEGEDGEERDPETEEPLWASRTVNGSRLVPYSCRENYSDSEEEDDDDVASSRQVL 276
VED+E EGE+ +E + ++ L + + L Y N SEEED + S+R+
Sbjct: 148 VEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKY----NLDASEEEDSNKKKSNRRSR 203
Query: 277 KDDSLSRHRPRRTHSKPLPPLTAKSAGGRLETSVQGGGGLAMNDRAAAAGSLDRS 331
S R S P + + R +S Q + +R+ + GS RS
Sbjct: 204 SKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRS 258
>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
Length = 320
Score = 39.3 bits (90), Expect = 0.017
Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 4/115 (3%)
Query: 217 VEDEEGEGEDGEERDPETEEPLWASRTVNGSRLVPYSCRENYSDSEEEDDDDVASSRQVL 276
VED+E EGE+ +E + ++ L + + L Y N SEEED + S+R+
Sbjct: 148 VEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKY----NLDASEEEDSNKKKSNRRSR 203
Query: 277 KDDSLSRHRPRRTHSKPLPPLTAKSAGGRLETSVQGGGGLAMNDRAAAAGSLDRS 331
S R S P + + R +S Q + +R+ + GS RS
Sbjct: 204 SKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRS 258
>gi|28467003 kinase interacting stathmin [Homo sapiens]
Length = 419
Score = 38.9 bits (89), Expect = 0.022
Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 1/90 (1%)
Query: 783 TPCLKIRNMFDPVMEIGDQWHLAIQEAILEKCSDNDGIVHIAVDK-NSREGCVYVKCLSP 841
TP L++ N+ D ++ + + E + E+C +V + V K N G V+V+ +
Sbjct: 320 TPVLRLLNVLDDDYLENEEEYEDVVEDVKEECQKYGPVVSLLVPKENPGRGQVFVEYANA 379
Query: 842 EYAGKAFKALHGSWFDGKLVTVKYLRLDRY 871
+ A K L G FDGK V + L Y
Sbjct: 380 GDSKAAQKLLTGRMFDGKFVVATFYPLSAY 409
>gi|56676324 LEM domain containing 1 [Homo sapiens]
Length = 108
Score = 38.9 bits (89), Expect = 0.022
Identities = 19/35 (54%), Positives = 25/35 (71%)
Query: 12 LSDEELFSQLRRYGLSPGPVTESTRPVYLKKLKKL 46
LSD +L +QL + G SPGP+ STR +Y KKL +L
Sbjct: 7 LSDCKLQNQLEKLGFSPGPILPSTRKLYEKKLVQL 41
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 38.5 bits (88), Expect = 0.029
Identities = 41/135 (30%), Positives = 48/135 (35%), Gaps = 20/135 (14%)
Query: 112 ASGPESLLGGPGGASAAPAAGSKVLLGFSSDESDV-EASPRDQAGGGGRKDRASLQYRGL 170
A GP L G PG AA AG K D DV E P G G + G
Sbjct: 742 AQGPPGLQGMPGERGAAGIAGPK------GDRGDVGEKGPEGAPGKDGGRG-----LTGP 790
Query: 171 KAPPAPLAASEVTN-------SNSAERRKPHSWWGARRPAGPE-LQTPPGKDGAVEDEEG 222
PP P A+ + SA R G P GP PPG DG +
Sbjct: 791 IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGE 850
Query: 223 EGEDGEERDPETEEP 237
+GE G++ D P
Sbjct: 851 QGEAGQKGDAGAPGP 865
Score = 33.1 bits (74), Expect = 1.2
Identities = 45/169 (26%), Positives = 54/169 (31%), Gaps = 20/169 (11%)
Query: 70 NTAAATVAAAGPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPESLLGGPGGASAAP 129
N V GPA +A G R G+ PG +GP G PG
Sbjct: 800 NGEKGEVGPPGPAGSA----GARGAPGERGETGPPGPA---GFAGPPGADGQPGAKGEQG 852
Query: 130 AAGSKVLLGFSSDESDVEA-SPRDQAGGGGRKDRASLQYRGLKAPPAPLAASEVTNSNSA 188
AG K G + A P+ G G K RG + PP +A
Sbjct: 853 EAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGA-----RGAQGPPGATGFP-----GAA 902
Query: 189 ERRKPHSWWGARRPAGPELQTPPGKDGAVEDEEGEGEDGEERDPETEEP 237
R P G P GP P GKDG G G +P + P
Sbjct: 903 GRVGPPGSNGNPGPPGPP--GPSGKDGPKGARGDSGPPGRAGEPGLQGP 949
Score = 31.2 bits (69), Expect = 4.6
Identities = 42/155 (27%), Positives = 50/155 (32%), Gaps = 15/155 (9%)
Query: 79 AGPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPESLLGGPGGASAAPAAGSKVLLG 138
AGP A G G TPG ASG G PG +A A G G
Sbjct: 377 AGPTGAR----GPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPG 432
Query: 139 FSSDES----DVEASPRDQAGGGGRKDRASLQ-YRGLKAPPAPLAASEVTNSNSAERRKP 193
F P G G A + +G K P P E ++
Sbjct: 433 FPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR- 491
Query: 194 HSWWGAR-RPAGPELQTPPGKDGAVEDEEGEGEDG 227
GAR P G PPG+ GA + G+DG
Sbjct: 492 ----GARGEPGGVGPIGPPGERGAPGNRGFPGQDG 522
Score = 30.4 bits (67), Expect = 7.8
Identities = 28/121 (23%), Positives = 40/121 (33%), Gaps = 15/121 (12%)
Query: 121 GPGGASAAPA----AGSKVLLGFSSDESDVEASPRDQAGGGGRKDRASLQYRGLKAPPAP 176
GP GA P AG + ++G + P G + + G + PP P
Sbjct: 963 GPSGAEGPPGPQGLAGQRGIVGLPGQRGE-RGFPGLPGPSGEPGKQGAPGASGDRGPPGP 1021
Query: 177 LAASEVTNSNSAERRKPHSWWGARRPAGPELQTPPGKDGAVEDEEGEGEDGEERDPETEE 236
+ +T R+ P PPG+DGA + GE G P
Sbjct: 1022 VGPPGLTGPAGEPGRE----------GSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPG 1071
Query: 237 P 237
P
Sbjct: 1072 P 1072
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 38.5 bits (88), Expect = 0.029
Identities = 41/135 (30%), Positives = 48/135 (35%), Gaps = 20/135 (14%)
Query: 112 ASGPESLLGGPGGASAAPAAGSKVLLGFSSDESDV-EASPRDQAGGGGRKDRASLQYRGL 170
A GP L G PG AA AG K D DV E P G G + G
Sbjct: 673 AQGPPGLQGMPGERGAAGIAGPK------GDRGDVGEKGPEGAPGKDGGRG-----LTGP 721
Query: 171 KAPPAPLAASEVTN-------SNSAERRKPHSWWGARRPAGPE-LQTPPGKDGAVEDEEG 222
PP P A+ + SA R G P GP PPG DG +
Sbjct: 722 IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGE 781
Query: 223 EGEDGEERDPETEEP 237
+GE G++ D P
Sbjct: 782 QGEAGQKGDAGAPGP 796
Score = 33.1 bits (74), Expect = 1.2
Identities = 45/169 (26%), Positives = 54/169 (31%), Gaps = 20/169 (11%)
Query: 70 NTAAATVAAAGPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPESLLGGPGGASAAP 129
N V GPA +A G R G+ PG +GP G PG
Sbjct: 731 NGEKGEVGPPGPAGSA----GARGAPGERGETGPPGPA---GFAGPPGADGQPGAKGEQG 783
Query: 130 AAGSKVLLGFSSDESDVEA-SPRDQAGGGGRKDRASLQYRGLKAPPAPLAASEVTNSNSA 188
AG K G + A P+ G G K RG + PP +A
Sbjct: 784 EAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGA-----RGAQGPPGATGFP-----GAA 833
Query: 189 ERRKPHSWWGARRPAGPELQTPPGKDGAVEDEEGEGEDGEERDPETEEP 237
R P G P GP P GKDG G G +P + P
Sbjct: 834 GRVGPPGSNGNPGPPGPP--GPSGKDGPKGARGDSGPPGRAGEPGLQGP 880
Score = 31.2 bits (69), Expect = 4.6
Identities = 42/155 (27%), Positives = 50/155 (32%), Gaps = 15/155 (9%)
Query: 79 AGPAAAAAAGMGVRPVSGDLSYLRTPGGLCRISASGPESLLGGPGGASAAPAAGSKVLLG 138
AGP A G G TPG ASG G PG +A A G G
Sbjct: 308 AGPTGAR----GPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPG 363
Query: 139 FSSDES----DVEASPRDQAGGGGRKDRASLQ-YRGLKAPPAPLAASEVTNSNSAERRKP 193
F P G G A + +G K P P E ++
Sbjct: 364 FPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR- 422
Query: 194 HSWWGAR-RPAGPELQTPPGKDGAVEDEEGEGEDG 227
GAR P G PPG+ GA + G+DG
Sbjct: 423 ----GARGEPGGVGPIGPPGERGAPGNRGFPGQDG 453
Score = 30.4 bits (67), Expect = 7.8
Identities = 28/121 (23%), Positives = 40/121 (33%), Gaps = 15/121 (12%)
Query: 121 GPGGASAAPA----AGSKVLLGFSSDESDVEASPRDQAGGGGRKDRASLQYRGLKAPPAP 176
GP GA P AG + ++G + P G + + G + PP P
Sbjct: 894 GPSGAEGPPGPQGLAGQRGIVGLPGQRGE-RGFPGLPGPSGEPGKQGAPGASGDRGPPGP 952
Query: 177 LAASEVTNSNSAERRKPHSWWGARRPAGPELQTPPGKDGAVEDEEGEGEDGEERDPETEE 236
+ +T R+ P PPG+DGA + GE G P
Sbjct: 953 VGPPGLTGPAGEPGRE----------GSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPG 1002
Query: 237 P 237
P
Sbjct: 1003 P 1003
>gi|7706435 headcase [Homo sapiens]
Length = 543
Score = 38.5 bits (88), Expect = 0.029
Identities = 29/83 (34%), Positives = 37/83 (44%), Gaps = 7/83 (8%)
Query: 53 QHRSGGRGNKTRNSNNN--NTAAATVAAAGPAAAAAAGMGVRPVSGDLSYLRTPGGLCRI 110
++ GGR NK NS+ + A +AAAG A AAA G + PG
Sbjct: 5 KNSKGGRKNKRANSSGDEQENGAGALAAAGAAGAAAGGALAAAAGCGAAAAGAPGAGGAA 64
Query: 111 SASGPESLLGGPGGASAAPAAGS 133
A G G G A+AA AAG+
Sbjct: 65 GAGG-----AGTGAANAAAAAGA 82
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,118,007
Number of Sequences: 37866
Number of extensions: 2013397
Number of successful extensions: 9324
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 349
Number of HSP's that attempted gapping in prelim test: 8387
Number of HSP's gapped (non-prelim): 1086
length of query: 911
length of database: 18,247,518
effective HSP length: 111
effective length of query: 800
effective length of database: 14,044,392
effective search space: 11235513600
effective search space used: 11235513600
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.