Guide to the Human Genome
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Search of human proteins with 7705320

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7705320 hepatoma-derived growth factor, related protein 3
[Homo sapiens]
         (203 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7705320 hepatoma-derived growth factor, related protein 3 [Ho...   422   e-119
gi|4758516 hepatoma-derived growth factor isoform a [Homo sapiens]    204   5e-53
gi|48255931 hepatoma-derived growth factor-related protein 2 iso...   200   8e-52
gi|14249158 hepatoma-derived growth factor-related protein 2 iso...   200   8e-52
gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo...   187   4e-48
gi|190014586 PC4 and SFRS1 interacting protein 1 isoform 1 [Homo...   187   4e-48
gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo ...   187   4e-48
gi|186928819 hepatoma-derived growth factor isoform b [Homo sapi...   158   3e-39
gi|186928821 hepatoma-derived growth factor isoform c [Homo sapi...   157   8e-39
gi|110681712 hepatoma derived growth factor-like 1 [Homo sapiens]     137   8e-33
gi|40556376 cytokine-like nuclear factor n-pac [Homo sapiens]          71   7e-13
gi|115529449 upstream binding transcription factor, RNA polymera...    52   3e-07
gi|115529451 upstream binding transcription factor, RNA polymera...    52   3e-07
gi|7657671 upstream binding transcription factor, RNA polymerase...    52   3e-07
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H...    52   5e-07
gi|21396500 HIRA interacting protein 3 [Homo sapiens]                  47   9e-06
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    47   1e-05
gi|168229156 NFKB activating protein [Homo sapiens]                    46   2e-05
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           46   2e-05
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           46   2e-05
gi|148839376 PWWP domain containing 2 isoform 1 [Homo sapiens]         45   3e-05
gi|4504191 mutS homolog 6 [Homo sapiens]                               45   4e-05
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    45   4e-05
gi|7657013 apoptosis antagonizing transcription factor [Homo sap...    45   4e-05
gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H...    43   2e-04
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         43   2e-04
gi|197927454 DEK oncogene isoform 2 [Homo sapiens]                     43   2e-04
gi|4503249 DEK oncogene isoform 1 [Homo sapiens]                       43   2e-04
gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]        43   2e-04
gi|13540523 nucleosomal binding protein 1 [Homo sapiens]               41   6e-04

>gi|7705320 hepatoma-derived growth factor, related protein 3 [Homo
           sapiens]
          Length = 203

 Score =  422 bits (1086), Expect = e-119
 Identities = 203/203 (100%), Positives = 203/203 (100%)

Query: 1   MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPK 60
           MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPK
Sbjct: 1   MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPK 60

Query: 61  DLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADA 120
           DLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADA
Sbjct: 61  DLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADA 120

Query: 121 SSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSS 180
           SSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSS
Sbjct: 121 SSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSS 180

Query: 181 EGGDAGNDTRNTTSDLQKTSEGT 203
           EGGDAGNDTRNTTSDLQKTSEGT
Sbjct: 181 EGGDAGNDTRNTTSDLQKTSEGT 203


>gi|4758516 hepatoma-derived growth factor isoform a [Homo sapiens]
          Length = 240

 Score =  204 bits (518), Expect = 5e-53
 Identities = 110/221 (49%), Positives = 138/221 (62%), Gaps = 23/221 (10%)

Query: 5   RPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFP 64
           R +EYK GDLVFAKMKGYPHWPARIDE+PE AVK  ANKY +FFFGTHETAFLGPKDLFP
Sbjct: 6   RQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFP 65

Query: 65  YKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQS----------SSETEGEG 114
           Y+E K+KFGK NKRKGF+EGLWEIENNP VK +GYQ+ Q++S          ++E +G+ 
Sbjct: 66  YEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDK 125

Query: 115 GNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKS---YTSKKSSKQSRKSPGDEDDKDC 171
              A+ SS+EEG ++  D   K KNEK   KR+       S K  K++    G+E +   
Sbjct: 126 KGNAEGSSDEEG-KLVIDEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAAT 184

Query: 172 KE---------EENKSSSEGGDAGNDTRNTTSDLQKTSEGT 203
            E         E+N + SE G      +    +  +  E T
Sbjct: 185 LEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEAT 225


>gi|48255931 hepatoma-derived growth factor-related protein 2
           isoform 1 [Homo sapiens]
          Length = 671

 Score =  200 bits (508), Expect = 8e-52
 Identities = 104/203 (51%), Positives = 124/203 (61%), Gaps = 23/203 (11%)

Query: 6   PREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPY 65
           P  +K GDLVFAKMKGYPHWPARID++ +GAVKPP NKYPIFFFGTHETAFLGPKDLFPY
Sbjct: 2   PHAFKPGDLVFAKMKGYPHWPARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPKDLFPY 61

Query: 66  KEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEE 125
            + KDK+GK NKRKGFNEGLWEI+NNP      Y A    SSS++E    N AD S  +E
Sbjct: 62  DKCKDKYGKPNKRKGFNEGLWEIQNNP---HASYSAPPPVSSSDSEAPEANPADGSDADE 118

Query: 126 ------------------GDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDED 167
                              DR+E D    + ++ +G KRK        SK++RK+  D D
Sbjct: 119 DDEDRGVMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLD 178

Query: 168 DKDC--KEEENKSSSEGGDAGND 188
                  EEEN  SS   +  +D
Sbjct: 179 QASVSPSEEENSESSSESEKTSD 201


>gi|14249158 hepatoma-derived growth factor-related protein 2
           isoform 2 [Homo sapiens]
          Length = 670

 Score =  200 bits (508), Expect = 8e-52
 Identities = 104/203 (51%), Positives = 124/203 (61%), Gaps = 23/203 (11%)

Query: 6   PREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPY 65
           P  +K GDLVFAKMKGYPHWPARID++ +GAVKPP NKYPIFFFGTHETAFLGPKDLFPY
Sbjct: 2   PHAFKPGDLVFAKMKGYPHWPARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPKDLFPY 61

Query: 66  KEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEE 125
            + KDK+GK NKRKGFNEGLWEI+NNP      Y A    SSS++E    N AD S  +E
Sbjct: 62  DKCKDKYGKPNKRKGFNEGLWEIQNNP---HASYSAPPPVSSSDSEAPEANPADGSDADE 118

Query: 126 ------------------GDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDED 167
                              DR+E D    + ++ +G KRK        SK++RK+  D D
Sbjct: 119 DDEDRGVMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLD 178

Query: 168 DKDC--KEEENKSSSEGGDAGND 188
                  EEEN  SS   +  +D
Sbjct: 179 QASVSPSEEENSESSSESEKTSD 201


>gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
           sapiens]
          Length = 530

 Score =  187 bits (476), Expect = 4e-48
 Identities = 89/160 (55%), Positives = 116/160 (72%), Gaps = 7/160 (4%)

Query: 7   REYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYK 66
           R++K GDL+FAKMKGYPHWPAR+DE+P+GAVKPP NK PIFFFGTHETAFLGPKD+FPY 
Sbjct: 3   RDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYS 62

Query: 67  EYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEG 126
           E K+K+GK NKRKGFNEGLWEI+NNP VKF+  QA  +QS++ ++ E      + S+E+ 
Sbjct: 63  ENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDT 122

Query: 127 DRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDE 166
           D  E     K  NE     +    T+ K++++ RK   ++
Sbjct: 123 DHEE-----KASNEDV--TKAVDITTPKAARRGRKRKAEK 155



 Score = 32.0 bits (71), Expect = 0.37
 Identities = 22/94 (23%), Positives = 44/94 (46%), Gaps = 19/94 (20%)

Query: 105 QSSSETEGEGGNTADASSEEEGDRVEEDGKGKRK-----------------NEKAGSKRK 147
           +S  +   + G T+ + SEEEGD  +++G+ KRK                 +EK  + RK
Sbjct: 258 ESKRKNLAKTGVTSTSDSEEEGD--DQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRK 315

Query: 148 KSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSE 181
           +    +  ++Q  K  G + +    E++ ++S +
Sbjct: 316 RKQEEQMETEQQNKDEGKKPEVKKVEKKRETSMD 349



 Score = 29.6 bits (65), Expect = 1.8
 Identities = 19/75 (25%), Positives = 37/75 (49%), Gaps = 11/75 (14%)

Query: 125 EGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEE-ENK------ 177
           E D + E+ K K+K ++    +K+    ++  K+  K   + D K+ K+E E+K      
Sbjct: 207 ESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAK 266

Query: 178 ----SSSEGGDAGND 188
               S+S+  + G+D
Sbjct: 267 TGVTSTSDSEEEGDD 281


>gi|190014586 PC4 and SFRS1 interacting protein 1 isoform 1 [Homo
           sapiens]
          Length = 333

 Score =  187 bits (476), Expect = 4e-48
 Identities = 89/160 (55%), Positives = 116/160 (72%), Gaps = 7/160 (4%)

Query: 7   REYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYK 66
           R++K GDL+FAKMKGYPHWPAR+DE+P+GAVKPP NK PIFFFGTHETAFLGPKD+FPY 
Sbjct: 3   RDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYS 62

Query: 67  EYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEG 126
           E K+K+GK NKRKGFNEGLWEI+NNP VKF+  QA  +QS++ ++ E      + S+E+ 
Sbjct: 63  ENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDT 122

Query: 127 DRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDE 166
           D  E     K  NE     +    T+ K++++ RK   ++
Sbjct: 123 DHEE-----KASNEDV--TKAVDITTPKAARRGRKRKAEK 155



 Score = 29.6 bits (65), Expect = 1.8
 Identities = 19/75 (25%), Positives = 37/75 (49%), Gaps = 11/75 (14%)

Query: 125 EGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEE-ENK------ 177
           E D + E+ K K+K ++    +K+    ++  K+  K   + D K+ K+E E+K      
Sbjct: 207 ESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAK 266

Query: 178 ----SSSEGGDAGND 188
               S+S+  + G+D
Sbjct: 267 TGVTSTSDSEEEGDD 281


>gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
           sapiens]
          Length = 530

 Score =  187 bits (476), Expect = 4e-48
 Identities = 89/160 (55%), Positives = 116/160 (72%), Gaps = 7/160 (4%)

Query: 7   REYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYK 66
           R++K GDL+FAKMKGYPHWPAR+DE+P+GAVKPP NK PIFFFGTHETAFLGPKD+FPY 
Sbjct: 3   RDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYS 62

Query: 67  EYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEG 126
           E K+K+GK NKRKGFNEGLWEI+NNP VKF+  QA  +QS++ ++ E      + S+E+ 
Sbjct: 63  ENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDT 122

Query: 127 DRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDE 166
           D  E     K  NE     +    T+ K++++ RK   ++
Sbjct: 123 DHEE-----KASNEDV--TKAVDITTPKAARRGRKRKAEK 155



 Score = 32.0 bits (71), Expect = 0.37
 Identities = 22/94 (23%), Positives = 44/94 (46%), Gaps = 19/94 (20%)

Query: 105 QSSSETEGEGGNTADASSEEEGDRVEEDGKGKRK-----------------NEKAGSKRK 147
           +S  +   + G T+ + SEEEGD  +++G+ KRK                 +EK  + RK
Sbjct: 258 ESKRKNLAKTGVTSTSDSEEEGD--DQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRK 315

Query: 148 KSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSE 181
           +    +  ++Q  K  G + +    E++ ++S +
Sbjct: 316 RKQEEQMETEQQNKDEGKKPEVKKVEKKRETSMD 349



 Score = 29.6 bits (65), Expect = 1.8
 Identities = 19/75 (25%), Positives = 37/75 (49%), Gaps = 11/75 (14%)

Query: 125 EGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEE-ENK------ 177
           E D + E+ K K+K ++    +K+    ++  K+  K   + D K+ K+E E+K      
Sbjct: 207 ESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAK 266

Query: 178 ----SSSEGGDAGND 188
               S+S+  + G+D
Sbjct: 267 TGVTSTSDSEEEGDD 281


>gi|186928819 hepatoma-derived growth factor isoform b [Homo
           sapiens]
          Length = 256

 Score =  158 bits (399), Expect = 3e-39
 Identities = 90/200 (45%), Positives = 117/200 (58%), Gaps = 23/200 (11%)

Query: 26  PARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGL 85
           P  IDE+PE AVK  ANKY +FFFGTHETAFLGPKDLFPY+E K+KFGK NKRKGF+EGL
Sbjct: 43  PHTIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGL 102

Query: 86  WEIENNPGVKFTGYQAIQQQS----------SSETEGEGGNTADASSEEEGDRVEEDGKG 135
           WEIENNP VK +GYQ+ Q++S          ++E +G+    A+ SS+EEG ++  D   
Sbjct: 103 WEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEG-KLVIDEPA 161

Query: 136 KRKNEKAGSKRKKS---YTSKKSSKQSRKSPGDEDDKDCKE---------EENKSSSEGG 183
           K KNEK   KR+       S K  K++    G+E +    E         E+N + SE G
Sbjct: 162 KEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPG 221

Query: 184 DAGNDTRNTTSDLQKTSEGT 203
                 +    +  +  E T
Sbjct: 222 SGRGPPQEEEEEEDEEEEAT 241


>gi|186928821 hepatoma-derived growth factor isoform c [Homo
           sapiens]
          Length = 233

 Score =  157 bits (396), Expect = 8e-39
 Identities = 90/199 (45%), Positives = 117/199 (58%), Gaps = 23/199 (11%)

Query: 27  ARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLW 86
           A IDE+PE AVK  ANKY +FFFGTHETAFLGPKDLFPY+E K+KFGK NKRKGF+EGLW
Sbjct: 21  AVIDEMPEAAVKSTANKYQVFFFGTHETAFLGPKDLFPYEESKEKFGKPNKRKGFSEGLW 80

Query: 87  EIENNPGVKFTGYQAIQQQS----------SSETEGEGGNTADASSEEEGDRVEEDGKGK 136
           EIENNP VK +GYQ+ Q++S          ++E +G+    A+ SS+EEG ++  D   K
Sbjct: 81  EIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEGDGDKKGNAEGSSDEEG-KLVIDEPAK 139

Query: 137 RKNEKAGSKRKKS---YTSKKSSKQSRKSPGDEDDKDCKE---------EENKSSSEGGD 184
            KNEK   KR+       S K  K++    G+E +    E         E+N + SE G 
Sbjct: 140 EKNEKGALKRRAGDLLEDSPKRPKEAENPEGEEKEAATLEVERPLPMEVEKNSTPSEPGS 199

Query: 185 AGNDTRNTTSDLQKTSEGT 203
                +    +  +  E T
Sbjct: 200 GRGPPQEEEEEEDEEEEAT 218


>gi|110681712 hepatoma derived growth factor-like 1 [Homo sapiens]
          Length = 251

 Score =  137 bits (344), Expect = 8e-33
 Identities = 74/180 (41%), Positives = 105/180 (58%), Gaps = 15/180 (8%)

Query: 9   YKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPKDLFPYKEY 68
           YK+GDLVFAK+KGY HWPARI+ + +       N+Y +FFFGTHETAFL PK LFPYKE 
Sbjct: 9   YKSGDLVFAKLKGYAHWPARIEHMTQ------PNRYQVFFFGTHETAFLSPKRLFPYKEC 62

Query: 69  KDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSE------TEGEGGNTADASS 122
           K+KFGK NKR+GF+ GLWEIENNP V+ +      ++ S +         EG       +
Sbjct: 63  KEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEGDEDKPTHA 122

Query: 123 EEEGDRV-EEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSE 181
              GD + + D     + EK   KR      + + K+ +++  D++++   E E  + +E
Sbjct: 123 GGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEEE--AEAERAAEAE 180


>gi|40556376 cytokine-like nuclear factor n-pac [Homo sapiens]
          Length = 553

 Score = 70.9 bits (172), Expect = 7e-13
 Identities = 55/195 (28%), Positives = 92/195 (47%), Gaps = 24/195 (12%)

Query: 10  KAGDLVFAKMKGYPHWPARIDELPEGAVKPPANK-YPIFFFGTHETAFLGPKDLFPYKEY 68
           + GDLV+ K+  YP WP +I   P+   KP   K + + FFGT + A++  + L PY  +
Sbjct: 7   RLGDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAH 66

Query: 69  KDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSE----- 123
           K++  K NK K F + +  +E     +F      + Q+SS    +  N  ++S E     
Sbjct: 67  KEEMIKINKGKRFQQAVDAVE-----EFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPN 121

Query: 124 ----------EEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPG--DEDDKDC 171
                      EG   +  G+GK++     S+R      K++ +QS +  G   +D+KD 
Sbjct: 122 SGDEKRKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSPRKRGRPPKDEKDL 181

Query: 172 KEEENKSSSEGGDAG 186
              E+ S+ +G  AG
Sbjct: 182 TIPES-STVKGMMAG 195


>gi|115529449 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 52.0 bits (123), Expect = 3e-07
 Identities = 37/139 (26%), Positives = 59/139 (42%), Gaps = 15/139 (10%)

Query: 57  LGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGN 116
           L P+D   YKEY      SNKRK   +        P  K +    +Q +S SE + E   
Sbjct: 600 LSPQDRAAYKEYI-----SNKRKSMTK-----LRGPNPK-SSRTTLQSKSESEEDDE--- 645

Query: 117 TADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEEN 176
             D   E+E +  E+D  G    +   S    S    +   ++ +   DEDD +  +E+ 
Sbjct: 646 -EDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDE 704

Query: 177 KSSSEGGDAGNDTRNTTSD 195
            + SEG  + + +   +SD
Sbjct: 705 DNESEGSSSSSSSSGDSSD 723


>gi|115529451 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 52.0 bits (123), Expect = 3e-07
 Identities = 37/139 (26%), Positives = 59/139 (42%), Gaps = 15/139 (10%)

Query: 57  LGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGN 116
           L P+D   YKEY      SNKRK   +        P  K +    +Q +S SE + E   
Sbjct: 600 LSPQDRAAYKEYI-----SNKRKSMTK-----LRGPNPK-SSRTTLQSKSESEEDDE--- 645

Query: 117 TADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEEN 176
             D   E+E +  E+D  G    +   S    S    +   ++ +   DEDD +  +E+ 
Sbjct: 646 -EDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDE 704

Query: 177 KSSSEGGDAGNDTRNTTSD 195
            + SEG  + + +   +SD
Sbjct: 705 DNESEGSSSSSSSSGDSSD 723


>gi|7657671 upstream binding transcription factor, RNA polymerase I
           isoform a [Homo sapiens]
          Length = 764

 Score = 52.0 bits (123), Expect = 3e-07
 Identities = 37/139 (26%), Positives = 59/139 (42%), Gaps = 15/139 (10%)

Query: 57  LGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGN 116
           L P+D   YKEY      SNKRK   +        P  K +    +Q +S SE + E   
Sbjct: 637 LSPQDRAAYKEYI-----SNKRKSMTK-----LRGPNPK-SSRTTLQSKSESEEDDE--- 682

Query: 117 TADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEEN 176
             D   E+E +  E+D  G    +   S    S    +   ++ +   DEDD +  +E+ 
Sbjct: 683 -EDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDE 741

Query: 177 KSSSEGGDAGNDTRNTTSD 195
            + SEG  + + +   +SD
Sbjct: 742 DNESEGSSSSSSSSGDSSD 760


>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
           sapiens]
          Length = 1094

 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 29/98 (29%), Positives = 52/98 (53%), Gaps = 4/98 (4%)

Query: 106 SSSETEGEGGNTADASSE--EEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSP 163
           SSS++E E G+ +    E  EEGD  E+  +     + + S R+    +K+++K++ K+ 
Sbjct: 688 SSSDSESESGSESGEQGESGEEGDSNEDSSEDSSSEQDSESGRESGLENKRTAKRNSKAK 747

Query: 164 GDEDDKDCKEEENKSSSEGGDAGNDTRNTTSDLQKTSE 201
           G  D +D ++E  KS +   D+ ND  ++  D    SE
Sbjct: 748 GKSDSEDGEKENEKSKT--SDSSNDESSSIEDSSSDSE 783



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 30/128 (23%), Positives = 67/128 (52%), Gaps = 9/128 (7%)

Query: 74  KSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDG 133
           +++ +K ++E   E +++     +  ++  +       GE G++ + SSE+     E+D 
Sbjct: 669 ENSAKKFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDSSEDSSS--EQDS 726

Query: 134 KGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTT 193
           +  R   ++G + K+  T+K++SK   KS  D +D + + E++K+S    D  +   +++
Sbjct: 727 ESGR---ESGLENKR--TAKRNSKAKGKS--DSEDGEKENEKSKTSDSSNDESSSIEDSS 779

Query: 194 SDLQKTSE 201
           SD +  SE
Sbjct: 780 SDSESESE 787



 Score = 41.2 bits (95), Expect = 6e-04
 Identities = 25/104 (24%), Positives = 52/104 (50%), Gaps = 5/104 (4%)

Query: 103 QQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKS 162
           Q +S  E +    ++ D+SSE++ +   E G   ++  K  SK K    S+   K++ KS
Sbjct: 703 QGESGEEGDSNEDSSEDSSSEQDSESGRESGLENKRTAKRNSKAKGKSDSEDGEKENEKS 762

Query: 163 PGDE--DDKDCKEEENKSSSEG---GDAGNDTRNTTSDLQKTSE 201
              +  +D+    E++ S SE     ++ +++R  T + +K ++
Sbjct: 763 KTSDSSNDESSSIEDSSSDSESESEPESESESRRVTKEKEKKTK 806


>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
          Length = 556

 Score = 47.4 bits (111), Expect = 9e-06
 Identities = 29/102 (28%), Positives = 52/102 (50%), Gaps = 3/102 (2%)

Query: 87  EIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKR 146
           ++E N G K    +  +Q+S  E   +     +   EEE ++ E++ KG  K     + R
Sbjct: 210 KVEGNKGTK--SLKESEQESEEEILAQKKEQREEEVEEE-EKEEDEEKGDWKPRTRSNGR 266

Query: 147 KKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGND 188
           +KS   ++S KQ  ++     D D +EE+ +++S G D+G D
Sbjct: 267 RKSAREERSCKQKSQAKRLLGDSDSEEEQKEAASSGDDSGRD 308



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 28/102 (27%), Positives = 47/102 (46%), Gaps = 8/102 (7%)

Query: 102 IQQQSSSETEGEGGNTADASSEEEGD--RVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQS 159
           +Q++S   T+ +GG     SSE+E D  + E   KG RK  + GS   +    ++    S
Sbjct: 313 VQRKSEDRTQLKGGKRLSGSSEDEEDSGKGEPTAKGSRKMARLGSTSGEESDLEREVSDS 372

Query: 160 RKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTTSDLQKTSE 201
               G +      E +N+SS +    G  TR+++S    + E
Sbjct: 373 EAGGGPQG-----ERKNRSSKKSSRKGR-TRSSSSSSDGSPE 408



 Score = 29.3 bits (64), Expect = 2.4
 Identities = 30/136 (22%), Positives = 55/136 (40%), Gaps = 8/136 (5%)

Query: 66  KEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQ--AIQQQSSSETEGEGGNTADASSE 123
           ++ +++  +  K +   +G W+    P  +  G +  A +++S  +         D+ SE
Sbjct: 237 EQREEEVEEEEKEEDEEKGDWK----PRTRSNGRRKSAREERSCKQKSQAKRLLGDSDSE 292

Query: 124 EEGDRVEEDGKGK-RKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEG 182
           EE       G    R  E    ++ +  T  K  K+   S  DE+D    E   K S + 
Sbjct: 293 EEQKEAASSGDDSGRDREPPVQRKSEDRTQLKGGKRLSGSSEDEEDSGKGEPTAKGSRKM 352

Query: 183 GDAGNDTRNTTSDLQK 198
              G+ T    SDL++
Sbjct: 353 ARLGS-TSGEESDLER 367



 Score = 28.5 bits (62), Expect = 4.1
 Identities = 18/90 (20%), Positives = 40/90 (44%), Gaps = 3/90 (3%)

Query: 102 IQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRK 161
           +++Q+  +         + S E E + V+   K    N+   S ++    S++     +K
Sbjct: 177 VKKQAPGKASVSRKQAREESEESEAEPVQRTAKKVEGNKGTKSLKESEQESEEEILAQKK 236

Query: 162 SPGDEDDKDCKEEENKSSSEGGDAGNDTRN 191
              ++ +++ +EEE +   E GD    TR+
Sbjct: 237 ---EQREEEVEEEEKEEDEEKGDWKPRTRS 263


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 37/139 (26%), Positives = 62/139 (44%), Gaps = 25/139 (17%)

Query: 58  GPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNT 117
           G K+L   +E+K + G+  ++K   +G  +  N             ++   E  GEG   
Sbjct: 692 GEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQE----------MEEGGEEEHGEG--- 738

Query: 118 ADASSEEEGDRVEE---DGKGKRK---NEKAGSKRKKSYTSKKSSKQSRKSPGDE--DDK 169
                EEEGDR EE   +G+GK +    E  G + K+    KK  +  ++  G+E  D  
Sbjct: 739 ----EEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQG 794

Query: 170 DCKEEENKSSSEGGDAGND 188
           + +EEE +   E  + G +
Sbjct: 795 EGEEEETEGRGEEKEEGGE 813



 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 29/111 (26%), Positives = 51/111 (45%), Gaps = 3/111 (2%)

Query: 73  GKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQ-QSSSETEGEGGNTADASSEEEGDRVEE 131
           GK  + +   EG  E E   G +  G    ++ +   E EGE G   +   E EG+  EE
Sbjct: 822 GKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEE 881

Query: 132 DGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEG 182
           +G+G+ + E  G   ++    +   ++  +  G+E++ + K EE     EG
Sbjct: 882 EGEGEGEEEGEGEGEEEE--GEGEGEEEGEGEGEEEEGEGKGEEEGEEGEG 930



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 32/121 (26%), Positives = 54/121 (44%), Gaps = 6/121 (4%)

Query: 83  EGLWEIENNPGVKFTGYQAIQQQSSSETEGEG-GNTADASSEEEGDRVEEDGKGKRKNEK 141
           EG  + E   G +  G +   Q    E E EG G   +   E EG  VEE GKG+R+ E+
Sbjct: 772 EGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEE-GKGEREEEE 830

Query: 142 AGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTTSDLQKTSE 201
              + ++    ++   +  +  G+E++ + K EE     EG + G +      + +   E
Sbjct: 831 EEGEGEE----EEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGE 886

Query: 202 G 202
           G
Sbjct: 887 G 887



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 29/110 (26%), Positives = 56/110 (50%), Gaps = 6/110 (5%)

Query: 73   GKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEED 132
            G+    +G  EG  E     G +  G +  +++   E EGEG    +   E EG+   E+
Sbjct: 970  GEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEE 1029

Query: 133  GKG---KRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDK--DCKEEENK 177
            G+G   + + E+ G +R+K    ++ ++++R+   +E+ K  +  EEEN+
Sbjct: 1030 GEGEGEEEEGEEEGEEREKEGEGEE-NRRNREEEEEEEGKYQETGEEENE 1078



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 26/101 (25%), Positives = 45/101 (44%), Gaps = 1/101 (0%)

Query: 83   EGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRV-EEDGKGKRKNEK 141
            EG WE E   G      +   +    E EGE         EEEG+   EE+G+G+ + E 
Sbjct: 952  EGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEG 1011

Query: 142  AGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEG 182
             G + ++     +   +  +  G+E++ + + EE +   EG
Sbjct: 1012 EGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEG 1052



 Score = 41.2 bits (95), Expect = 6e-04
 Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 1/84 (1%)

Query: 104 QQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSP 163
           ++   E EGEG        EEEG+  EE+G+GK + E    + ++     +   +  +  
Sbjct: 825 EREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGE 884

Query: 164 GD-EDDKDCKEEENKSSSEGGDAG 186
           G+ E++ + + EE +   EG + G
Sbjct: 885 GEGEEEGEGEGEEEEGEGEGEEEG 908



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 28/118 (23%), Positives = 54/118 (45%), Gaps = 3/118 (2%)

Query: 67  EYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEG 126
           E +++ G+  + +G  +G  E E   G +  G +   +    E EGEG    +   EEE 
Sbjct: 841 EGEEEEGEGEEEEGEGKGEEEGEEGEGEE-EGEEGEGEGEEEEGEGEGEEEGEGEGEEEE 899

Query: 127 DRVE--EDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEG 182
              E  E+G+G+ + E+   K ++     +   +  +  G+ +D + + EE +   EG
Sbjct: 900 GEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEG 957



 Score = 38.1 bits (87), Expect = 0.005
 Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 4/78 (5%)

Query: 109 ETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDD 168
           E EGEG    +   E EG+  EE+G+GK + E    + +      +   +  +  G+E++
Sbjct: 897 EEEGEG----EGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEE 952

Query: 169 KDCKEEENKSSSEGGDAG 186
            + + EE +   EG + G
Sbjct: 953 GEWEGEEEEGEGEGEEEG 970



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 27/113 (23%), Positives = 48/113 (42%), Gaps = 3/113 (2%)

Query: 79   KGFNEGLWEIENNPGV---KFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKG 135
            +G  EG  E E   G    +  G +   +    E EGEG +      EEEG+   E+ +G
Sbjct: 903  EGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEG 962

Query: 136  KRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGND 188
            + + E+ G    +    +   ++      +E+ ++  EEE +   EG   G +
Sbjct: 963  EGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEE 1015



 Score = 36.6 bits (83), Expect = 0.015
 Identities = 29/142 (20%), Positives = 63/142 (44%), Gaps = 11/142 (7%)

Query: 66  KEYKDKFGKSNK-RKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEG---EGGNTADAS 121
           ++ +++ GK  K  +  ++G  E E   G      +  +++   E EG   E G      
Sbjct: 775 RKKEERAGKEEKGEEEGDQGEGEEEETEG------RGEEKEEGGEVEGGEVEEGKGEREE 828

Query: 122 SEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENK-SSS 180
            EEEG+  EE+G+G+ +  +   +  +    ++  +   +  G+E + + +EEE +    
Sbjct: 829 EEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGE 888

Query: 181 EGGDAGNDTRNTTSDLQKTSEG 202
           E G+   +      + ++  EG
Sbjct: 889 EEGEGEGEEEEGEGEGEEEGEG 910



 Score = 36.6 bits (83), Expect = 0.015
 Identities = 29/115 (25%), Positives = 55/115 (47%), Gaps = 6/115 (5%)

Query: 67   EYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEG 126
            E ++  G+  + +G  EG  E E     +  G +  + +   E EGE G       EEEG
Sbjct: 982  EEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGE--GEGEEEEG 1039

Query: 127  DRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSE 181
               EE+G+ +R+ E  G + +++   ++  +   +  G+E+++    EE K  S+
Sbjct: 1040 ---EEEGE-EREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSK 1090



 Score = 32.0 bits (71), Expect = 0.37
 Identities = 20/92 (21%), Positives = 41/92 (44%), Gaps = 5/92 (5%)

Query: 99  YQAIQQQSSSETEGEGGNTADASSEEEGDRVEE----DGKGKRKNEKAGSKRKKSYTSKK 154
           +Q  +++   + +G G        E+E    EE    DG+ + + E+    +K+     +
Sbjct: 669 WQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEME 728

Query: 155 SSKQSRKSPGDEDDKDCKEEENKSSSEGGDAG 186
              +     G+E++ D +EEE +   EG + G
Sbjct: 729 EGGEEEHGEGEEEEGD-REEEEEKEGEGKEEG 759



 Score = 31.2 bits (69), Expect = 0.63
 Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 8/76 (10%)

Query: 113 EGGNTADASSEEEGDRVEED-GKGKRKNEKAGSKR---KKSYTSKKSSKQSRKSPGDEDD 168
           EG + A+   +EE ++ E+D G+G+ +    G K    K+ +  +   +Q +K    E +
Sbjct: 661 EGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQK----ERE 716

Query: 169 KDCKEEENKSSSEGGD 184
           +  ++E N+   EGG+
Sbjct: 717 QGHQKERNQEMEEGGE 732



 Score = 31.2 bits (69), Expect = 0.63
 Identities = 29/140 (20%), Positives = 57/140 (40%), Gaps = 6/140 (4%)

Query: 67   EYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGE---GGNTADASSE 123
            E ++  GK  +     EG  E E   G    G +   ++   E EGE   G    +   E
Sbjct: 913  EEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDG-EGEGEEEEGEWEGEEEEGEGEGEEEGE 971

Query: 124  EEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGG 183
             EG+  E +G+ + + E  G + +     ++  +   +  G+ ++++  E E +   E G
Sbjct: 972  GEGEEGEGEGE-EEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEG 1030

Query: 184  DA-GNDTRNTTSDLQKTSEG 202
            +  G +        ++  EG
Sbjct: 1031 EGEGEEEEGEEEGEEREKEG 1050


>gi|168229156 NFKB activating protein [Homo sapiens]
          Length = 415

 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 39/159 (24%), Positives = 70/159 (44%), Gaps = 9/159 (5%)

Query: 25  WPARIDELPEGAVKPP--ANKYPIFFFGTHETAFLGPKDLFP----YKEYKDKFGKSNKR 78
           WP+ +D+  E +++    + +  I   G  E   L PK+  P    +   +D+  K +  
Sbjct: 114 WPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTT 173

Query: 79  KGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRK 138
                   + + +   K    +  +++SS     +    +D+ S+ E D  +ED K + K
Sbjct: 174 SASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAK 233

Query: 139 NEKAGSKRKKSYT---SKKSSKQSRKSPGDEDDKDCKEE 174
             K   K+KK  +    KK SK+SRK   D   K+ +EE
Sbjct: 234 KAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEE 272



 Score = 29.6 bits (65), Expect = 1.8
 Identities = 18/72 (25%), Positives = 35/72 (48%), Gaps = 4/72 (5%)

Query: 124 EEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGG 183
           +E   VE++   K     + S+ +K   S +S ++S+K       K   + ++K  SE  
Sbjct: 158 DEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKK----RRKKKSSKRKHKKYSEDS 213

Query: 184 DAGNDTRNTTSD 195
           D+ +D+   +SD
Sbjct: 214 DSDSDSETDSSD 225


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 27/113 (23%), Positives = 56/113 (49%), Gaps = 8/113 (7%)

Query: 99  YQAIQQQSSSETEGEGGNTADASSE------EEGDRVEEDGKGKRKNEKAGSKRKKSYTS 152
           Y +  +  SS +  E GN  +   E      EE + VEED +   + ++ G + ++    
Sbjct: 179 YGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEE 238

Query: 153 KKSSKQSRKSPGDEDDKDCKEEENK--SSSEGGDAGNDTRNTTSDLQKTSEGT 203
           ++  ++  +   ++D++D KEE N   + SE  D+G+++ + T    ++  GT
Sbjct: 239 EEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGT 291



 Score = 30.8 bits (68), Expect = 0.83
 Identities = 19/93 (20%), Positives = 47/93 (50%), Gaps = 5/93 (5%)

Query: 100 QAIQQQSSSETEGEGGNTADA-SSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQ 158
           Q+ +++ +SE  G    T  + SS+E+G+  E + +G  ++ +   + ++     +   +
Sbjct: 168 QSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDE 227

Query: 159 SRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRN 191
                G+E++++ +EEE +   E  +   D R+
Sbjct: 228 D----GEEEEEEEEEEEEEEEEEEEEYEQDERD 256



 Score = 29.3 bits (64), Expect = 2.4
 Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 2/59 (3%)

Query: 106 SSSETEGEGGNTADASSE--EEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKS 162
           S  E +GE     D  +E  E+ D +      + KNEK GSKRK        +K+ + S
Sbjct: 5   SREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPS 63



 Score = 27.3 bits (59), Expect = 9.1
 Identities = 28/130 (21%), Positives = 49/130 (37%), Gaps = 14/130 (10%)

Query: 52  HETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETE 111
           HET   G  D       +      N+ +G  E   ++E +  V+    +  +     E E
Sbjct: 183 HETGSSGSSD-------EQGNNTENEEEGVEE---DVEEDEEVEEDAEEDEEVDEDGEEE 232

Query: 112 GEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQ----SRKSPGDED 167
            E     +   EEE +  E+D + +++       R ++  S   S      S +S    D
Sbjct: 233 EEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTD 292

Query: 168 DKDCKEEENK 177
             D K++E K
Sbjct: 293 GSDEKKKERK 302


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 27/113 (23%), Positives = 56/113 (49%), Gaps = 8/113 (7%)

Query: 99  YQAIQQQSSSETEGEGGNTADASSE------EEGDRVEEDGKGKRKNEKAGSKRKKSYTS 152
           Y +  +  SS +  E GN  +   E      EE + VEED +   + ++ G + ++    
Sbjct: 179 YGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEE 238

Query: 153 KKSSKQSRKSPGDEDDKDCKEEENK--SSSEGGDAGNDTRNTTSDLQKTSEGT 203
           ++  ++  +   ++D++D KEE N   + SE  D+G+++ + T    ++  GT
Sbjct: 239 EEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGT 291



 Score = 30.8 bits (68), Expect = 0.83
 Identities = 19/93 (20%), Positives = 47/93 (50%), Gaps = 5/93 (5%)

Query: 100 QAIQQQSSSETEGEGGNTADA-SSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQ 158
           Q+ +++ +SE  G    T  + SS+E+G+  E + +G  ++ +   + ++     +   +
Sbjct: 168 QSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDE 227

Query: 159 SRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRN 191
                G+E++++ +EEE +   E  +   D R+
Sbjct: 228 D----GEEEEEEEEEEEEEEEEEEEEYEQDERD 256



 Score = 29.3 bits (64), Expect = 2.4
 Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 2/59 (3%)

Query: 106 SSSETEGEGGNTADASSE--EEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKS 162
           S  E +GE     D  +E  E+ D +      + KNEK GSKRK        +K+ + S
Sbjct: 5   SREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPS 63



 Score = 27.3 bits (59), Expect = 9.1
 Identities = 28/130 (21%), Positives = 49/130 (37%), Gaps = 14/130 (10%)

Query: 52  HETAFLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETE 111
           HET   G  D       +      N+ +G  E   ++E +  V+    +  +     E E
Sbjct: 183 HETGSSGSSD-------EQGNNTENEEEGVEE---DVEEDEEVEEDAEEDEEVDEDGEEE 232

Query: 112 GEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQ----SRKSPGDED 167
            E     +   EEE +  E+D + +++       R ++  S   S      S +S    D
Sbjct: 233 EEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTD 292

Query: 168 DKDCKEEENK 177
             D K++E K
Sbjct: 293 GSDEKKKERK 302


>gi|148839376 PWWP domain containing 2 isoform 1 [Homo sapiens]
          Length = 590

 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 7/84 (8%)

Query: 7   REYKAGDLVFAKMKGYPHWPARIDELPEGAV---KPPANKYPIFFFGTHETAFLGPKDLF 63
           R    GD+V+ K+ G+P WPAR+ ++  G     +P   +  + +FG+  T+FL    L 
Sbjct: 486 RTVAVGDIVWGKIHGFPWWPARVLDISLGQKEDGEPSWREAKVSWFGSPTTSFLSISKLS 545

Query: 64  PYKE-YKDKFGKSNK---RKGFNE 83
           P+ E +K +F +  K   RK   E
Sbjct: 546 PFSEFFKLRFNRKKKGMYRKAITE 569


>gi|4504191 mutS homolog 6 [Homo sapiens]
          Length = 1360

 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 56/214 (26%), Positives = 86/214 (40%), Gaps = 27/214 (12%)

Query: 2   ARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAV----KPPANKYPIFFFGTHET-AF 56
           A P   ++  GDLV+AKM+GYP WP  +   P        K  + +  + FF    T  +
Sbjct: 83  AAPTSCDFSPGDLVWAKMEGYPWWPCLVYNHPFDGTFIREKGKSVRVHVQFFDDSPTRGW 142

Query: 57  LGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEI----------ENNPGVKFTGYQAIQQQS 106
           +  + L PY   K K  ++ K   F     EI           N   +K        + S
Sbjct: 143 VSKRLLKPYTGSKSK--EAQKGGHFYSAKPEILRAMQRADEALNKDKIKRLELAVCDEPS 200

Query: 107 --SSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKK---SSKQSRK 161
               E E E G T      EE + +E + + + K +  GS+R      K+   S  +S  
Sbjct: 201 EPEEEEEMEVGTTYVTDKSEEDNEIESEEEVQPKTQ--GSRRSSRQIKKRRVISDSESDI 258

Query: 162 SPGDEDDKDCKEEENKS---SSEGGDAGNDTRNT 192
              D + K   +EE  S   SS  GD+ ++  N+
Sbjct: 259 GGSDVEFKPDTKEEGSSDEISSGVGDSESEGLNS 292


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 27/106 (25%), Positives = 51/106 (48%), Gaps = 7/106 (6%)

Query: 103 QQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKS 162
           + +  S+T+ +     D  S +     + D K  +K+EK G K  K    KK +K++ +S
Sbjct: 424 KDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAES 483

Query: 163 PGDEDDKDCKEEENKSSSEGG-------DAGNDTRNTTSDLQKTSE 201
              E D + K+++  S  + G       DA  DT +T ++  ++S+
Sbjct: 484 TEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSK 529



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 11/112 (9%)

Query: 91  NPGVKFTGYQAIQQQS----SSETEGEGGNTADASSEEEGDRVEEDGKGK-------RKN 139
           N  +K+T Y     +     SS+ E E    A   S++    V++D K K         +
Sbjct: 275 NYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTD 334

Query: 140 EKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRN 191
            ++G  + +   +KK  K+ +K    +D K   E  +  S +  DA ND+RN
Sbjct: 335 AESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRN 386



 Score = 35.8 bits (81), Expect = 0.026
 Identities = 30/137 (21%), Positives = 53/137 (38%), Gaps = 4/137 (2%)

Query: 65  YKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEE 124
           Y +Y  K  K N +K  +    E E++   K    +  +     + + +     +++  E
Sbjct: 280 YTKYTKKDTKKNAKKSSDA---ESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAE 336

Query: 125 EGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGD 184
            GD  +E  K  +K++K   K  K   +KK  + +    GD  D        K +S+  D
Sbjct: 337 SGDSKDER-KDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDD 395

Query: 185 AGNDTRNTTSDLQKTSE 201
              D +  T      SE
Sbjct: 396 KKKDAKKITFSTDSESE 412



 Score = 31.6 bits (70), Expect = 0.48
 Identities = 21/86 (24%), Positives = 38/86 (44%), Gaps = 3/86 (3%)

Query: 117 TADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEE-E 175
           + D+ SE E    ++D K  +K+ K  +K  KS  + + S  +   P  +  K  K+E +
Sbjct: 406 STDSESELESKESQKDEKKDKKDSKTDNK--KSVKNDEESTDADSEPKGDSKKGKKDEKK 463

Query: 176 NKSSSEGGDAGNDTRNTTSDLQKTSE 201
            K  S+  D   D +      +  S+
Sbjct: 464 GKKDSKKDDKKKDAKKNAESTEMESD 489



 Score = 30.8 bits (68), Expect = 0.83
 Identities = 21/84 (25%), Positives = 36/84 (42%), Gaps = 22/84 (26%)

Query: 137 RKNEKAGSKRKKSYTSKKSSKQSRKSPG--DEDDKDCKEEENK----------------- 177
           + N K  S +   YT K + K ++KS     ED KD K++  K                 
Sbjct: 270 QNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKD 329

Query: 178 ---SSSEGGDAGNDTRNTTSDLQK 198
              + +E GD+ ++ ++T  D +K
Sbjct: 330 TESTDAESGDSKDERKDTKKDKKK 353



 Score = 30.8 bits (68), Expect = 0.83
 Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 12/88 (13%)

Query: 110 TEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDE--D 167
           T+ E G+  DA ++    +       K+K+    +K+    T  +S  +S++S  DE  D
Sbjct: 370 TDTESGDAKDARNDSRNLKKASKNDDKKKD----AKKITFSTDSESELESKESQKDEKKD 425

Query: 168 DKDCKEEENKSSSEGGDAGNDTRNTTSD 195
            KD K +  KS        ND  +T +D
Sbjct: 426 KKDSKTDNKKS------VKNDEESTDAD 447



 Score = 28.9 bits (63), Expect = 3.1
 Identities = 18/76 (23%), Positives = 36/76 (47%), Gaps = 2/76 (2%)

Query: 123 EEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEG 182
           EE+  R  E  K   K+     + KKS +S +++ +S+ S      K+C +++ K S   
Sbjct: 149 EEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNS--KTVSKNCSQKDKKDSKNS 206

Query: 183 GDAGNDTRNTTSDLQK 198
                +  +T ++ +K
Sbjct: 207 KKTNTEFLHTKNNPKK 222


>gi|7657013 apoptosis antagonizing transcription factor [Homo
           sapiens]
          Length = 560

 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 38/139 (27%), Positives = 58/139 (41%), Gaps = 32/139 (23%)

Query: 73  GKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEED 132
           GK+  RK +NE  WE +  PG           +  S+ EG G   ++    EE D   ED
Sbjct: 73  GKTTSRKAWNEDHWE-QTLPG--------SSDEEISDEEGSGDEDSEGLGLEEYD---ED 120

Query: 133 GKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPG----------------DEDDKDCKEEEN 176
             G  + ++ G  R+    SKKS   S K+PG                D+     +EE+ 
Sbjct: 121 DLGAAEEQECGDHRE----SKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDE 176

Query: 177 KSSSEGGDAGNDTRNTTSD 195
           +S  E GD   D++  + +
Sbjct: 177 ESGMEEGDDAEDSQGESEE 195



 Score = 27.3 bits (59), Expect = 9.1
 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 10/99 (10%)

Query: 65  YKEYKDKFGKSNKRKGFN-EGLWEIENNPGVKFT-GYQAIQQQSSSETEGEGGNTADASS 122
           ++E K     S K  GF+ + + + E     KFT G   +      E E  G    D + 
Sbjct: 133 HRESKKSRSHSAKTPGFSVQSISDFE-----KFTKGMDDLGSSEEEEDEESGMEEGDDAE 187

Query: 123 EEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRK 161
           + +G+  EED  G R +E  G     +++S K S++  K
Sbjct: 188 DSQGES-EEDRAGDRNSEDDGV--VMTFSSVKVSEEVEK 223


>gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo
           sapiens]
          Length = 1082

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 23/100 (23%), Positives = 45/100 (45%), Gaps = 6/100 (6%)

Query: 108 SETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDED 167
           S++EGE G T  A S+ E +   +            S    +    +  ++ R S  ++ 
Sbjct: 679 SDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQS 738

Query: 168 DKDCKEE------ENKSSSEGGDAGNDTRNTTSDLQKTSE 201
           ++D K +      E K  +   D G+D+ +++S+ + TSE
Sbjct: 739 EEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSE 778



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 19/83 (22%), Positives = 39/83 (46%), Gaps = 4/83 (4%)

Query: 103 QQQSSSETEGEGGNTADASSEEEGDRVEEDGKGK----RKNEKAGSKRKKSYTSKKSSKQ 158
           + +S S++  E G+   +S  +  D+ E++ KG+     ++E+ G ++ K    ++  + 
Sbjct: 698 ESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEA 757

Query: 159 SRKSPGDEDDKDCKEEENKSSSE 181
           S    G +      E E  S SE
Sbjct: 758 SSSDEGSDSSSSSSESEMTSESE 780



 Score = 35.0 bits (79), Expect = 0.044
 Identities = 23/83 (27%), Positives = 34/83 (40%), Gaps = 10/83 (12%)

Query: 103 QQQSSSETEGEGGNTADASSEEEGDRVEEDGKG----------KRKNEKAGSKRKKSYTS 152
           +  S S +E   G ++  S  E+ D  EE G+G          KRK +K   +RK   +S
Sbjct: 700 ESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGEASS 759

Query: 153 KKSSKQSRKSPGDEDDKDCKEEE 175
                 S  S  + +     EEE
Sbjct: 760 SDEGSDSSSSSSESEMTSESEEE 782



 Score = 32.7 bits (73), Expect = 0.22
 Identities = 43/169 (25%), Positives = 62/169 (36%), Gaps = 31/169 (18%)

Query: 14  LVFAKMKGY---PHWP-------ARIDELPE-----GAVKPPANKYPIFFFGTHETAFLG 58
           L+ AK  GY   P WP        R  E+PE        K    + P +     E+    
Sbjct: 630 LLNAKATGYQELPDWPEEAPDPSVRNVEVPEWTKCSNREKRKEKEKPFYSDSEGESGPTE 689

Query: 59  PKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTA 118
             D  P  E  +   KS+   G  E   E +N              +   E E +G  + 
Sbjct: 690 SADSDPESE-SESDSKSSSESGSGESSSESDN--------------EDQDEDEEKGRGSE 734

Query: 119 DASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDED 167
              SEE+G R  +    +RK E A S  + S +S  SS+    S  +E+
Sbjct: 735 SEQSEEDGKRKTKKKVPERKGE-ASSSDEGSDSSSSSSESEMTSESEEE 782



 Score = 30.8 bits (68), Expect = 0.83
 Identities = 15/66 (22%), Positives = 28/66 (42%)

Query: 136 KRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTTSD 195
           K  N +   +++K + S    +       D D +   E ++KSSSE G   + + +   D
Sbjct: 663 KCSNREKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSGESSSESDNED 722

Query: 196 LQKTSE 201
             +  E
Sbjct: 723 QDEDEE 728


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 57/235 (24%), Positives = 86/235 (36%), Gaps = 37/235 (15%)

Query: 3    RPRPREYKAGDLVFAKMKGYPHWPARIDEL-----PEGAVKPPANKYPIFFFGTHETAFL 57
            RP+P++ +A +   AK    P  P    EL      EG   P + K         +    
Sbjct: 2434 RPKPKKARAAEESGAKG---PRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAG 2490

Query: 58   G---PKDLFPYKEYKDKFGKSNKRKGF---NEGLWEIENNPGVKFTGY---------QAI 102
            G   PK L     Y    G S  +  +    +G    E  PG+ F            QA 
Sbjct: 2491 GWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAE 2550

Query: 103  Q------QQSSSETEGEGGNTADASS-------EEEGDRVEEDGKGK-RKNEKAGSKRKK 148
            Q      + SSS + G   +++ +SS       EEEGD+  + G G   +N  A S R  
Sbjct: 2551 QDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAA 2610

Query: 149  SYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTTSDLQKTSEGT 203
            S  S  SS  S  S             + SSS    + + + +++S    +S  +
Sbjct: 2611 SPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2665



 Score = 29.3 bits (64), Expect = 2.4
 Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 13/83 (15%)

Query: 103  QQQSSSETEGEGGNTADASSEEEGDRVEEDGK---GKRKNEKAGSKRKKSYTSK------ 153
            + + +S+  GEG +   A SEE G +    G+    K K ++A +  + + T +      
Sbjct: 2303 RSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPL 2362

Query: 154  ----KSSKQSRKSPGDEDDKDCK 172
                 S+  S+KSP +  DK  K
Sbjct: 2363 ALEPSSTPGSKKSPPEPVDKRAK 2385


>gi|197927454 DEK oncogene isoform 2 [Homo sapiens]
          Length = 341

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 6/115 (5%)

Query: 78  RKGFNEGLWEIENNPGV----KFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDG 133
           +K  ++G  +  N+ G+    K T    I    SS  E E  N  ++S +E+ +  EE  
Sbjct: 163 KKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPP 222

Query: 134 KGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGND 188
           K   K EK   K+K +  SKKS K +     D       +  +K  SE  D+ +D
Sbjct: 223 KKTAKREKP--KQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDD 275


>gi|4503249 DEK oncogene isoform 1 [Homo sapiens]
          Length = 375

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 6/115 (5%)

Query: 78  RKGFNEGLWEIENNPGV----KFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEEDG 133
           +K  ++G  +  N+ G+    K T    I    SS  E E  N  ++S +E+ +  EE  
Sbjct: 197 KKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPP 256

Query: 134 KGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSSEGGDAGND 188
           K   K EK   K+K +  SKKS K +     D       +  +K  SE  D+ +D
Sbjct: 257 KKTAKREKP--KQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDD 309


>gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]
          Length = 755

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 31/84 (36%), Positives = 44/84 (52%), Gaps = 12/84 (14%)

Query: 4   PRPREYKAGDLVFAKMKGYPHWPARIDELPEG------AVKPPANKYPIFFFGTHETAFL 57
           P  R    GD+V+AK+ G+P WPARI  +          V+  A    I +FG+  T+FL
Sbjct: 648 PDGRTICVGDIVWAKIYGFPWWPARILTITVSRKDNGLLVRQEAR---ISWFGSPTTSFL 704

Query: 58  GPKDLFPYKE-YKDKFGKSNKRKG 80
               L P+ E ++ +F K  KRKG
Sbjct: 705 ALSQLSPFLENFQSRFNK--KRKG 726


>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
          Length = 282

 Score = 41.2 bits (95), Expect = 6e-04
 Identities = 33/128 (25%), Positives = 54/128 (42%), Gaps = 15/128 (11%)

Query: 67  EYKDKFGKSNK-RKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEE 125
           E K + GK +K  KG  +G  +   N      G  A +++   + E   GN  D   + E
Sbjct: 139 EEKGEAGKEDKDEKGEEDGKEDKNGNE----KGEDAKEKEDGKKGEDGKGNGEDGKEKGE 194

Query: 126 GDRVEEDGK----------GKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEE 175
            ++ EED K          GK K +K   K  K    +K  +  ++  G  +++  KE+E
Sbjct: 195 DEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKE 254

Query: 176 NKSSSEGG 183
           +    E G
Sbjct: 255 DLKEEEEG 262



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 3/83 (3%)

Query: 103 QQQSSSETEGEGGNTADASSEEEGDRVEEDGK-GKRKNEKAGSKRKKSYTSKKSSKQSRK 161
           ++    + E +     +A  E++ ++ EEDGK  K  NEK    ++K    K    +   
Sbjct: 127 EEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNG 186

Query: 162 SPGDEDDKDCKEEENKSSSEGGD 184
             G E  +D KEEE++   E GD
Sbjct: 187 EDGKEKGEDEKEEEDR--KETGD 207



 Score = 36.2 bits (82), Expect = 0.020
 Identities = 22/105 (20%), Positives = 47/105 (44%), Gaps = 9/105 (8%)

Query: 102 IQQQSSSETEGEGGN-----TADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSS 156
           +++++  +   +GG       A+  +EEE  + +E+ + + K E    K  K    ++  
Sbjct: 100 VKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGE--AGKEDKDEKGEEDG 157

Query: 157 KQSRKSPGDEDDKDCKEEENKSSSEGGDAGNDTRNTTSDLQKTSE 201
           K+ +   G+E  +D KE+E+    E G    +      + +K  E
Sbjct: 158 KEDKN--GNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEE 200



 Score = 35.8 bits (81), Expect = 0.026
 Identities = 31/118 (26%), Positives = 53/118 (44%), Gaps = 13/118 (11%)

Query: 97  TGYQAIQQQSSSET--EGEGGNTADASSEEEGDRVEEDG------KGKRKNEKAGSKRKK 148
           T  +A+ ++  +E    GE   T   +SE+E   V+E+       KG  K E   ++ K 
Sbjct: 66  TKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKN 125

Query: 149 SYTSKKSSKQSR---KSPGDEDDKDCK-EEENKSSSEGGDAGNDTRNTTSDLQKTSEG 202
               +K  ++ +   K    ++DKD K EE+ K    G + G D +    D +K  +G
Sbjct: 126 EEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKE-KEDGKKGEDG 182



 Score = 29.3 bits (64), Expect = 2.4
 Identities = 13/46 (28%), Positives = 27/46 (58%)

Query: 103 QQQSSSETEGEGGNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKK 148
           +++     E EGGN  +A  E+E  + EE+GK + + ++   K+++
Sbjct: 232 EKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEE 277



 Score = 28.9 bits (63), Expect = 3.1
 Identities = 29/124 (23%), Positives = 49/124 (39%), Gaps = 10/124 (8%)

Query: 66  KEYKDKFGKSNKRK---GFNEGLWEIENNPGVKF-----TGYQAIQQQSSSETEGEGGNT 117
           KE KD+ G+ + ++   G  +G    E   G K       G    ++    + E +   T
Sbjct: 146 KEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKET 205

Query: 118 ADASSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENK 177
            D    E+G   E+  K + K+ K     K+    K+    + +  G E +   +EEE K
Sbjct: 206 GDGKENEDGK--EKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGK 263

Query: 178 SSSE 181
              E
Sbjct: 264 EEDE 267


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.304    0.127    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,209,042
Number of Sequences: 37866
Number of extensions: 466792
Number of successful extensions: 6018
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 386
Number of HSP's successfully gapped in prelim test: 404
Number of HSP's that attempted gapping in prelim test: 2810
Number of HSP's gapped (non-prelim): 2582
length of query: 203
length of database: 18,247,518
effective HSP length: 97
effective length of query: 106
effective length of database: 14,574,516
effective search space: 1544898696
effective search space used: 1544898696
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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