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Search of human proteins with 14110395
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14110395 X-box binding protein 1 isoform XBP1(U) [Homo
sapiens]
(261 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14110395 X-box binding protein 1 isoform XBP1(U) [Homo sapiens] 518 e-147
gi|118640873 X-box binding protein 1 isoform XBP1(S) [Homo sapiens] 316 1e-86
gi|28872798 CCAAT/enhancer binding protein delta [Homo sapiens] 48 1e-05
gi|194239643 activating transcription factor 7 isoform 3 [Homo s... 47 2e-05
gi|5802980 activating transcription factor 7 isoform 2 [Homo sap... 47 2e-05
gi|194239640 activating transcription factor 7 isoform 1 [Homo s... 47 2e-05
gi|28872800 CCAAT/enhancer binding protein epsilon [Homo sapiens] 47 2e-05
gi|102469037 jun D proto-oncogene [Homo sapiens] 46 4e-05
gi|56550067 cAMP responsive element binding protein 3-like 2 [Ho... 45 6e-05
gi|209954788 activating transcription factor 6 beta isoform b [H... 45 6e-05
gi|20631977 activating transcription factor 6 beta isoform a [Ho... 45 6e-05
gi|4758616 jun oncogene [Homo sapiens] 44 1e-04
gi|191252814 RIMS binding protein 3B [Homo sapiens] 44 1e-04
gi|191252806 RIMS binding protein 3C [Homo sapiens] 44 1e-04
gi|153792195 DKFZP434H0735 protein [Homo sapiens] 44 1e-04
gi|56549111 optineurin [Homo sapiens] 44 1e-04
gi|56549109 optineurin [Homo sapiens] 44 1e-04
gi|20149572 optineurin [Homo sapiens] 44 1e-04
gi|56549107 optineurin [Homo sapiens] 44 1e-04
gi|8924246 basic leucine zipper transcription factor, ATF-like 3... 44 1e-04
gi|34335186 cAMP responsive element modulator isoform a [Homo sa... 44 2e-04
gi|34335214 cAMP responsive element modulator isoform o [Homo sa... 44 2e-04
gi|34335210 cAMP responsive element modulator isoform m [Homo sa... 44 2e-04
gi|34335202 cAMP responsive element modulator isoform k [Homo sa... 43 3e-04
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 42 5e-04
gi|56786157 activating transcription factor 6 [Homo sapiens] 42 5e-04
gi|16418355 cAMP responsive element binding protein 3-like 1 [Ho... 42 5e-04
gi|20149576 nuclear factor erythroid 2-like 2 isoform 1 [Homo sa... 42 7e-04
gi|224028259 nuclear factor erythroid 2-like 2 isoform 3 [Homo s... 42 7e-04
gi|224028257 nuclear factor erythroid 2-like 2 isoform 2 [Homo s... 42 7e-04
>gi|14110395 X-box binding protein 1 isoform XBP1(U) [Homo sapiens]
Length = 261
Score = 518 bits (1334), Expect = e-147
Identities = 261/261 (100%), Positives = 261/261 (100%)
Query: 1 MVVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARK 60
MVVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARK
Sbjct: 1 MVVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARK 60
Query: 61 RQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLR 120
RQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLR
Sbjct: 61 RQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLR 120
Query: 121 EKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAALRLRAPLQQVQAQL 180
EKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAALRLRAPLQQVQAQL
Sbjct: 121 EKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAALRLRAPLQQVQAQL 180
Query: 181 SPLQNISPWILAVLTLQIQSLISCWAFWTTWTQSCSSNALPQSLPAWRSSQRSTQKDPVP 240
SPLQNISPWILAVLTLQIQSLISCWAFWTTWTQSCSSNALPQSLPAWRSSQRSTQKDPVP
Sbjct: 181 SPLQNISPWILAVLTLQIQSLISCWAFWTTWTQSCSSNALPQSLPAWRSSQRSTQKDPVP 240
Query: 241 YQPPFLCQWGRHQPSWKPLMN 261
YQPPFLCQWGRHQPSWKPLMN
Sbjct: 241 YQPPFLCQWGRHQPSWKPLMN 261
>gi|118640873 X-box binding protein 1 isoform XBP1(S) [Homo sapiens]
Length = 376
Score = 316 bits (809), Expect = 1e-86
Identities = 166/166 (100%), Positives = 166/166 (100%)
Query: 1 MVVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARK 60
MVVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARK
Sbjct: 1 MVVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARK 60
Query: 61 RQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLR 120
RQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLR
Sbjct: 61 RQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLR 120
Query: 121 EKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAA 166
EKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAA
Sbjct: 121 EKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAA 166
>gi|28872798 CCAAT/enhancer binding protein delta [Homo sapiens]
Length = 269
Score = 47.8 bits (112), Expect = 1e-05
Identities = 41/136 (30%), Positives = 64/136 (47%), Gaps = 13/136 (9%)
Query: 8 PNPADGTPKVLLLSGQPASAAG-----APAGQALPLMVPAQRGASPEAASGGLPQARK-- 60
P+ DG LL Q A+ A A AGQ P P +SP P K
Sbjct: 123 PDWGDGDAPGSLLPAQVAACAQTVVSLAAAGQPTPPTSPEPPRSSPRQTPAPGPAREKSA 182
Query: 61 -RQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLL 119
++ SPE + +R+ +N +A + +RD+ K R E++Q++V+L EN+KL +Q +
Sbjct: 183 GKRGPDRGSPEYR--QRRERNNIAVRKSRDKAKRRNQEMQQKLVELSAENEKL---HQRV 237
Query: 120 REKTHGLVVENQELRQ 135
+ T L Q +Q
Sbjct: 238 EQLTRDLAGLRQFFKQ 253
>gi|194239643 activating transcription factor 7 isoform 3 [Homo
sapiens]
Length = 462
Score = 46.6 bits (109), Expect = 2e-05
Identities = 44/174 (25%), Positives = 78/174 (44%), Gaps = 32/174 (18%)
Query: 35 ALPLMVPAQRGASPEAASGGLPQARKRQRLTHLSPEEKALRRKLKNRVAAQTARDRKKAR 94
A P + PAQ P ++GG +R+R P+E+ R +NR AA R ++K
Sbjct: 285 AQPQVSPAQ----PTPSTGG-----RRRRTVDEDPDERRQRFLERNRAAASRCRQKRKLW 335
Query: 95 MSELEQQVVDLEEENQKL-----LLENQL-----------------LREKTHGLVVENQE 132
+S LE++ +L +N +L LL N++ L++KT G + +E
Sbjct: 336 VSSLEKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKDCPVTALQKKTQGYLESPKE 395
Query: 133 LRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAALRLRAPLQQVQAQLS-PLQN 185
+ G A V + + + V +AE+ A + + + +LS P+Q+
Sbjct: 396 SSEPTGSPAPVIQHSSATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPIQS 449
>gi|5802980 activating transcription factor 7 isoform 2 [Homo
sapiens]
Length = 483
Score = 46.6 bits (109), Expect = 2e-05
Identities = 44/174 (25%), Positives = 78/174 (44%), Gaps = 32/174 (18%)
Query: 35 ALPLMVPAQRGASPEAASGGLPQARKRQRLTHLSPEEKALRRKLKNRVAAQTARDRKKAR 94
A P + PAQ P ++GG +R+R P+E+ R +NR AA R ++K
Sbjct: 306 AQPQVSPAQ----PTPSTGG-----RRRRTVDEDPDERRQRFLERNRAAASRCRQKRKLW 356
Query: 95 MSELEQQVVDLEEENQKL-----LLENQL-----------------LREKTHGLVVENQE 132
+S LE++ +L +N +L LL N++ L++KT G + +E
Sbjct: 357 VSSLEKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKDCPVTALQKKTQGYLESPKE 416
Query: 133 LRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAALRLRAPLQQVQAQLS-PLQN 185
+ G A V + + + V +AE+ A + + + +LS P+Q+
Sbjct: 417 SSEPTGSPAPVIQHSSATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPIQS 470
>gi|194239640 activating transcription factor 7 isoform 1 [Homo
sapiens]
Length = 494
Score = 46.6 bits (109), Expect = 2e-05
Identities = 44/174 (25%), Positives = 78/174 (44%), Gaps = 32/174 (18%)
Query: 35 ALPLMVPAQRGASPEAASGGLPQARKRQRLTHLSPEEKALRRKLKNRVAAQTARDRKKAR 94
A P + PAQ P ++GG +R+R P+E+ R +NR AA R ++K
Sbjct: 317 AQPQVSPAQ----PTPSTGG-----RRRRTVDEDPDERRQRFLERNRAAASRCRQKRKLW 367
Query: 95 MSELEQQVVDLEEENQKL-----LLENQL-----------------LREKTHGLVVENQE 132
+S LE++ +L +N +L LL N++ L++KT G + +E
Sbjct: 368 VSSLEKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKDCPVTALQKKTQGYLESPKE 427
Query: 133 LRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAALRLRAPLQQVQAQLS-PLQN 185
+ G A V + + + V +AE+ A + + + +LS P+Q+
Sbjct: 428 SSEPTGSPAPVIQHSSATAPSNGLSVRSAAEAVATSVLTQMASQRTELSMPIQS 481
>gi|28872800 CCAAT/enhancer binding protein epsilon [Homo sapiens]
Length = 281
Score = 46.6 bits (109), Expect = 2e-05
Identities = 35/109 (32%), Positives = 52/109 (47%), Gaps = 7/109 (6%)
Query: 4 VAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARKRQR 63
VA A P L GQP AP A P P + SP +G L + +K
Sbjct: 145 VAHCGQTAMHLPPTLAAPGQPLRVLKAPLATAAPPCSPLLKAPSP---AGPLHKGKKAVN 201
Query: 64 LTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKL 112
L E LRR+ +N +A + +RD+ K R+ E +Q+V++ EN++L
Sbjct: 202 KDSL---EYRLRRE-RNNIAVRKSRDKAKRRILETQQKVLEYMAENERL 246
>gi|102469037 jun D proto-oncogene [Homo sapiens]
Length = 347
Score = 45.8 bits (107), Expect = 4e-05
Identities = 33/115 (28%), Positives = 53/115 (46%), Gaps = 21/115 (18%)
Query: 8 PNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARKRQRLTHL 67
P A G P++ L +P + P+ P + P ++R+
Sbjct: 227 PPGALGPPRLAALKDEPQTVPDVPSFGESPPLSPIDMDT--------------QERI--- 269
Query: 68 SPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLREK 122
KA R++L+NR+AA R RK R+S LE++V L+ +N +L LLRE+
Sbjct: 270 ----KAERKRLRNRIAASKCRKRKLERISRLEEKVKTLKSQNTELASTASLLREQ 320
>gi|56550067 cAMP responsive element binding protein 3-like 2 [Homo
sapiens]
Length = 520
Score = 45.1 bits (105), Expect = 6e-05
Identities = 26/68 (38%), Positives = 42/68 (61%), Gaps = 3/68 (4%)
Query: 70 EEKAL---RRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLREKTHGL 126
EEKAL RRK+KN+++AQ +R +KK M LE++V EN +L + ++L L
Sbjct: 291 EEKALKKIRRKIKNKISAQESRRKKKEYMDSLEKKVESCSTENLELRKKVEVLENTNRTL 350
Query: 127 VVENQELR 134
+ + Q+L+
Sbjct: 351 LQQLQKLQ 358
>gi|209954788 activating transcription factor 6 beta isoform b [Homo
sapiens]
Length = 700
Score = 45.1 bits (105), Expect = 6e-05
Identities = 40/144 (27%), Positives = 66/144 (45%), Gaps = 14/144 (9%)
Query: 2 VVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARKR 61
VV+ P P+ P + Q S P + L+ A R PE + LP+ ++
Sbjct: 246 VVLTTVPMPSRAVPPSTTVLLQ--SLVQPPPVSPVVLIQGAIR-VQPEGPAPSLPRPERK 302
Query: 62 QRLTHLSP--------EEKALRRK---LKNRVAAQTARDRKKARMSELEQQVVDLEEENQ 110
+ P + K L+R+ +KNR +A +R +KK + LE ++ + +NQ
Sbjct: 303 SIVPAPMPGNSCPPEVDAKLLKRQQRMIKNRESACQSRRKKKEYLQGLEARLQAVLADNQ 362
Query: 111 KLLLENQLLREKTHGLVVENQELR 134
+L EN LR + L+ EN EL+
Sbjct: 363 QLRRENAALRRRLEALLAENSELK 386
>gi|20631977 activating transcription factor 6 beta isoform a [Homo
sapiens]
Length = 703
Score = 45.1 bits (105), Expect = 6e-05
Identities = 40/144 (27%), Positives = 66/144 (45%), Gaps = 14/144 (9%)
Query: 2 VVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARKR 61
VV+ P P+ P + Q S P + L+ A R PE + LP+ ++
Sbjct: 249 VVLTTVPMPSRAVPPSTTVLLQ--SLVQPPPVSPVVLIQGAIR-VQPEGPAPSLPRPERK 305
Query: 62 QRLTHLSP--------EEKALRRK---LKNRVAAQTARDRKKARMSELEQQVVDLEEENQ 110
+ P + K L+R+ +KNR +A +R +KK + LE ++ + +NQ
Sbjct: 306 SIVPAPMPGNSCPPEVDAKLLKRQQRMIKNRESACQSRRKKKEYLQGLEARLQAVLADNQ 365
Query: 111 KLLLENQLLREKTHGLVVENQELR 134
+L EN LR + L+ EN EL+
Sbjct: 366 QLRRENAALRRRLEALLAENSELK 389
>gi|4758616 jun oncogene [Homo sapiens]
Length = 331
Score = 43.9 bits (102), Expect = 1e-04
Identities = 40/127 (31%), Positives = 59/127 (46%), Gaps = 27/127 (21%)
Query: 22 GQPASAAGAP----AGQALPLMVPAQRGASPEAASGGLP------QARKRQRLT------ 65
G +S GAP AG A P P Q+ P +P QA K + T
Sbjct: 179 GALSSGGGAPSYGAAGLAFPAQ-PQQQQQPPHHLPQQMPVQHPRLQALKEEPQTVPEMPG 237
Query: 66 ---HLSPEE-------KALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLE 115
LSP + KA R++++NR+AA R RK R++ LE++V L+ +N +L
Sbjct: 238 ETPPLSPIDMESQERIKAERKRMRNRIAASKCRKRKLERIARLEEKVKTLKAQNSELAST 297
Query: 116 NQLLREK 122
+LRE+
Sbjct: 298 ANMLREQ 304
>gi|191252814 RIMS binding protein 3B [Homo sapiens]
Length = 1639
Score = 43.9 bits (102), Expect = 1e-04
Identities = 39/130 (30%), Positives = 68/130 (52%), Gaps = 19/130 (14%)
Query: 58 ARKRQRLTHLSPEEKALRRKLKNRVAAQTARDRK-------KARMSELEQQVVDLEEENQ 110
AR+RQ E + L +L+++ AQ +R+ + + R +E+ Q + E E +
Sbjct: 56 ARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQR 115
Query: 111 KLLLENQLLREKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAALRLR 170
+L QLL + G+V + +EL+++L EE +G+ RP G++E +A + R
Sbjct: 116 QL---QQLLHRERDGVVRQARELQRQLA-------EELVNRGHCSRP--GASEVSAAQCR 163
Query: 171 APLQQVQAQL 180
LQ+V AQL
Sbjct: 164 CRLQEVLAQL 173
>gi|191252806 RIMS binding protein 3C [Homo sapiens]
Length = 1639
Score = 43.9 bits (102), Expect = 1e-04
Identities = 39/130 (30%), Positives = 68/130 (52%), Gaps = 19/130 (14%)
Query: 58 ARKRQRLTHLSPEEKALRRKLKNRVAAQTARDRK-------KARMSELEQQVVDLEEENQ 110
AR+RQ E + L +L+++ AQ +R+ + + R +E+ Q + E E +
Sbjct: 56 ARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQR 115
Query: 111 KLLLENQLLREKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAALRLR 170
+L QLL + G+V + +EL+++L EE +G+ RP G++E +A + R
Sbjct: 116 QL---QQLLHRERDGVVRQARELQRQLA-------EELVNRGHCSRP--GASEVSAAQCR 163
Query: 171 APLQQVQAQL 180
LQ+V AQL
Sbjct: 164 CRLQEVLAQL 173
>gi|153792195 DKFZP434H0735 protein [Homo sapiens]
Length = 1639
Score = 43.9 bits (102), Expect = 1e-04
Identities = 39/130 (30%), Positives = 68/130 (52%), Gaps = 19/130 (14%)
Query: 58 ARKRQRLTHLSPEEKALRRKLKNRVAAQTARDRK-------KARMSELEQQVVDLEEENQ 110
AR+RQ E + L +L+++ AQ +R+ + + R +E+ Q + E E +
Sbjct: 56 ARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQR 115
Query: 111 KLLLENQLLREKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAALRLR 170
+L QLL + G+V + +EL+++L EE +G+ RP G++E +A + R
Sbjct: 116 QL---QQLLHRERDGVVRQARELQRQLA-------EELVNRGHCSRP--GASEVSAAQCR 163
Query: 171 APLQQVQAQL 180
LQ+V AQL
Sbjct: 164 CRLQEVLAQL 173
>gi|56549111 optineurin [Homo sapiens]
Length = 577
Score = 43.9 bits (102), Expect = 1e-04
Identities = 37/156 (23%), Positives = 67/156 (42%), Gaps = 6/156 (3%)
Query: 37 PLMVPAQRGASPEAASGGLPQARKRQRLTHLSPEE------KALRRKLKNRVAAQTARDR 90
PL ++ SP ++G P L +PEE + L + + A +
Sbjct: 5 PLSCLTEKEDSPSESTGNGPPHLAHPNLDTFTPEELLQQMKELLTENHQLKEAMKLNNQA 64
Query: 91 KKARMSELEQQVVDLEEENQKLLLENQLLREKTHGLVVENQELRQRLGMDALVAEEEAEA 150
K R EL +EE Q ++++ +E+ L EN++L++ LG +E +E
Sbjct: 65 MKGRFEELSAWTEKQKEERQFFEIQSKEAKERLMALSHENEKLKEELGKLKGKSERSSED 124
Query: 151 KGNEVRPVAGSAESAALRLRAPLQQVQAQLSPLQNI 186
++ R AE +LR + ++QA+ + L I
Sbjct: 125 PTDDSRLPRAEAEQEKDQLRTQVVRLQAEKADLLGI 160
>gi|56549109 optineurin [Homo sapiens]
Length = 577
Score = 43.9 bits (102), Expect = 1e-04
Identities = 37/156 (23%), Positives = 67/156 (42%), Gaps = 6/156 (3%)
Query: 37 PLMVPAQRGASPEAASGGLPQARKRQRLTHLSPEE------KALRRKLKNRVAAQTARDR 90
PL ++ SP ++G P L +PEE + L + + A +
Sbjct: 5 PLSCLTEKEDSPSESTGNGPPHLAHPNLDTFTPEELLQQMKELLTENHQLKEAMKLNNQA 64
Query: 91 KKARMSELEQQVVDLEEENQKLLLENQLLREKTHGLVVENQELRQRLGMDALVAEEEAEA 150
K R EL +EE Q ++++ +E+ L EN++L++ LG +E +E
Sbjct: 65 MKGRFEELSAWTEKQKEERQFFEIQSKEAKERLMALSHENEKLKEELGKLKGKSERSSED 124
Query: 151 KGNEVRPVAGSAESAALRLRAPLQQVQAQLSPLQNI 186
++ R AE +LR + ++QA+ + L I
Sbjct: 125 PTDDSRLPRAEAEQEKDQLRTQVVRLQAEKADLLGI 160
>gi|20149572 optineurin [Homo sapiens]
Length = 577
Score = 43.9 bits (102), Expect = 1e-04
Identities = 37/156 (23%), Positives = 67/156 (42%), Gaps = 6/156 (3%)
Query: 37 PLMVPAQRGASPEAASGGLPQARKRQRLTHLSPEE------KALRRKLKNRVAAQTARDR 90
PL ++ SP ++G P L +PEE + L + + A +
Sbjct: 5 PLSCLTEKEDSPSESTGNGPPHLAHPNLDTFTPEELLQQMKELLTENHQLKEAMKLNNQA 64
Query: 91 KKARMSELEQQVVDLEEENQKLLLENQLLREKTHGLVVENQELRQRLGMDALVAEEEAEA 150
K R EL +EE Q ++++ +E+ L EN++L++ LG +E +E
Sbjct: 65 MKGRFEELSAWTEKQKEERQFFEIQSKEAKERLMALSHENEKLKEELGKLKGKSERSSED 124
Query: 151 KGNEVRPVAGSAESAALRLRAPLQQVQAQLSPLQNI 186
++ R AE +LR + ++QA+ + L I
Sbjct: 125 PTDDSRLPRAEAEQEKDQLRTQVVRLQAEKADLLGI 160
>gi|56549107 optineurin [Homo sapiens]
Length = 577
Score = 43.9 bits (102), Expect = 1e-04
Identities = 37/156 (23%), Positives = 67/156 (42%), Gaps = 6/156 (3%)
Query: 37 PLMVPAQRGASPEAASGGLPQARKRQRLTHLSPEE------KALRRKLKNRVAAQTARDR 90
PL ++ SP ++G P L +PEE + L + + A +
Sbjct: 5 PLSCLTEKEDSPSESTGNGPPHLAHPNLDTFTPEELLQQMKELLTENHQLKEAMKLNNQA 64
Query: 91 KKARMSELEQQVVDLEEENQKLLLENQLLREKTHGLVVENQELRQRLGMDALVAEEEAEA 150
K R EL +EE Q ++++ +E+ L EN++L++ LG +E +E
Sbjct: 65 MKGRFEELSAWTEKQKEERQFFEIQSKEAKERLMALSHENEKLKEELGKLKGKSERSSED 124
Query: 151 KGNEVRPVAGSAESAALRLRAPLQQVQAQLSPLQNI 186
++ R AE +LR + ++QA+ + L I
Sbjct: 125 PTDDSRLPRAEAEQEKDQLRTQVVRLQAEKADLLGI 160
>gi|8924246 basic leucine zipper transcription factor, ATF-like 3
[Homo sapiens]
Length = 127
Score = 43.9 bits (102), Expect = 1e-04
Identities = 28/75 (37%), Positives = 44/75 (58%), Gaps = 6/75 (8%)
Query: 50 AASGGLPQARKRQRLTHLSPEE--KALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEE 107
AA G PQ + +Q+ SPE+ + +RR+ KNRVAAQ +R ++ + +L ++ LE+
Sbjct: 17 AAPGNQPQPQPQQQ----SPEDDDRKVRRREKNRVAAQRSRKKQTQKADKLHEEYESLEQ 72
Query: 108 ENQKLLLENQLLREK 122
EN L E L E+
Sbjct: 73 ENTMLRREIGKLTEE 87
>gi|34335186 cAMP responsive element modulator isoform a [Homo
sapiens]
Length = 300
Score = 43.5 bits (101), Expect = 2e-04
Identities = 37/122 (30%), Positives = 57/122 (46%), Gaps = 7/122 (5%)
Query: 3 VVAAAPNPADGTPKVLLLSGQ---PASAAGAPAGQALPLMVPAQRGASPEAASGGLPQAR 59
+V A ADGT + + Q A+ P Q +G A+ G L
Sbjct: 175 IVQYAAQSADGTQQFFVPGSQVVVQAATGDMPTYQIRAPTAALPQGVVMAASPGSL---H 231
Query: 60 KRQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLL 119
Q+L + ++ LR +KNR AA+ R RKK + LE +V LE +N+KL+ E + L
Sbjct: 232 SPQQLAEEATRKRELRL-MKNREAAKECRRRKKEYVKCLESRVAVLEVQNKKLIEELETL 290
Query: 120 RE 121
++
Sbjct: 291 KD 292
>gi|34335214 cAMP responsive element modulator isoform o [Homo
sapiens]
Length = 270
Score = 43.5 bits (101), Expect = 2e-04
Identities = 37/122 (30%), Positives = 57/122 (46%), Gaps = 7/122 (5%)
Query: 3 VVAAAPNPADGTPKVLLLSGQ---PASAAGAPAGQALPLMVPAQRGASPEAASGGLPQAR 59
+V A ADGT + + Q A+ P Q +G A+ G L
Sbjct: 145 IVQYAAQSADGTQQFFVPGSQVVVQAATGDMPTYQIRAPTAALPQGVVMAASPGSL---H 201
Query: 60 KRQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLL 119
Q+L + ++ LR +KNR AA+ R RKK + LE +V LE +N+KL+ E + L
Sbjct: 202 SPQQLAEEATRKRELRL-MKNREAAKECRRRKKEYVKCLESRVAVLEVQNKKLIEELETL 260
Query: 120 RE 121
++
Sbjct: 261 KD 262
>gi|34335210 cAMP responsive element modulator isoform m [Homo
sapiens]
Length = 245
Score = 43.5 bits (101), Expect = 2e-04
Identities = 37/122 (30%), Positives = 57/122 (46%), Gaps = 7/122 (5%)
Query: 3 VVAAAPNPADGTPKVLLLSGQ---PASAAGAPAGQALPLMVPAQRGASPEAASGGLPQAR 59
+V A ADGT + + Q A+ P Q +G A+ G L
Sbjct: 120 IVQYAAQSADGTQQFFVPGSQVVVQAATGDMPTYQIRAPTAALPQGVVMAASPGSL---H 176
Query: 60 KRQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLL 119
Q+L + ++ LR +KNR AA+ R RKK + LE +V LE +N+KL+ E + L
Sbjct: 177 SPQQLAEEATRKRELRL-MKNREAAKECRRRKKEYVKCLESRVAVLEVQNKKLIEELETL 235
Query: 120 RE 121
++
Sbjct: 236 KD 237
>gi|34335202 cAMP responsive element modulator isoform k [Homo
sapiens]
Length = 113
Score = 42.7 bits (99), Expect = 3e-04
Identities = 35/103 (33%), Positives = 53/103 (51%), Gaps = 5/103 (4%)
Query: 20 LSGQPASAAG-APAGQALPLMVPAQRGASPEAASGGLPQARKRQRLTHLSPEEKALRRKL 78
LSGQ ++A G P Q +G A+ G L Q+L + ++ LR +
Sbjct: 7 LSGQLSAATGDMPTYQIRAPTAALPQGVVMAASPGSL---HSPQQLAEEATRKRELRL-M 62
Query: 79 KNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLRE 121
KNR AA+ R RKK + LE +V LE +N+KL+ E + L++
Sbjct: 63 KNREAAKECRRRKKEYVKCLESRVAVLEVQNKKLIEELETLKD 105
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 42.0 bits (97), Expect = 5e-04
Identities = 38/108 (35%), Positives = 58/108 (53%), Gaps = 13/108 (12%)
Query: 71 EKALRRKLKNRVAAQTAR-----DRKKARMSELEQQVVDLEEENQKLLLENQLLREKTHG 125
E+ L+ + N++A R DRKKA +L ++ E+EN+KL LE REK +
Sbjct: 995 ERTLKTQAVNKLAEIMNRKDFKIDRKKANTQDLRKK----EKENRKLQLELNQEREKFNQ 1050
Query: 126 LVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAALRLRAPL 173
+VV++Q ++ M A + EE A NE++ S ES +LRA L
Sbjct: 1051 MVVKHQ--KELNDMQAQLVEECAHR--NELQMQLASKESDIEQLRAKL 1094
>gi|56786157 activating transcription factor 6 [Homo sapiens]
Length = 670
Score = 42.0 bits (97), Expect = 5e-04
Identities = 35/123 (28%), Positives = 58/123 (47%), Gaps = 6/123 (4%)
Query: 18 LLLSGQPASAAGAPAGQA---LPLMVPAQRGASPEAASGGLPQARKRQRLTHLSPEEKAL 74
+L S QP A Q + +VPA SP + + + + ++ + L
Sbjct: 248 VLPSAQPVLAVAGGVTQLPNHVVNVVPAPSANSPVNGKLSVTKPVLQSTMRNVGSDIAVL 307
Query: 75 RRK---LKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLREKTHGLVVENQ 131
RR+ +KNR +A +R +KK M LE ++ EN++L EN L+ + +V ENQ
Sbjct: 308 RRQQRMIKNRESACQSRKKKKEYMLGLEARLKAALSENEQLKKENGTLKRQLDEVVSENQ 367
Query: 132 ELR 134
L+
Sbjct: 368 RLK 370
>gi|16418355 cAMP responsive element binding protein 3-like 1 [Homo
sapiens]
Length = 519
Score = 42.0 bits (97), Expect = 5e-04
Identities = 25/68 (36%), Positives = 41/68 (60%), Gaps = 3/68 (4%)
Query: 70 EEKAL---RRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLREKTHGL 126
EEKAL RRK+KN+++AQ +R +KK + LE++V EN +L + + L L
Sbjct: 287 EEKALKRVRRKIKNKISAQESRRKKKEYVECLEKKVETFTSENNELWKKVETLENANRTL 346
Query: 127 VVENQELR 134
+ + Q+L+
Sbjct: 347 LQQLQKLQ 354
>gi|20149576 nuclear factor erythroid 2-like 2 isoform 1 [Homo
sapiens]
Length = 605
Score = 41.6 bits (96), Expect = 7e-04
Identities = 21/42 (50%), Positives = 29/42 (69%)
Query: 74 LRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLE 115
+RR+ KN+VAAQ R RK + ELEQ + L++E +KLL E
Sbjct: 501 IRRRGKNKVAAQNCRKRKLENIVELEQDLDHLKDEKEKLLKE 542
>gi|224028259 nuclear factor erythroid 2-like 2 isoform 3 [Homo
sapiens]
Length = 582
Score = 41.6 bits (96), Expect = 7e-04
Identities = 21/42 (50%), Positives = 29/42 (69%)
Query: 74 LRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLE 115
+RR+ KN+VAAQ R RK + ELEQ + L++E +KLL E
Sbjct: 478 IRRRGKNKVAAQNCRKRKLENIVELEQDLDHLKDEKEKLLKE 519
>gi|224028257 nuclear factor erythroid 2-like 2 isoform 2 [Homo
sapiens]
Length = 589
Score = 41.6 bits (96), Expect = 7e-04
Identities = 21/42 (50%), Positives = 29/42 (69%)
Query: 74 LRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLE 115
+RR+ KN+VAAQ R RK + ELEQ + L++E +KLL E
Sbjct: 485 IRRRGKNKVAAQNCRKRKLENIVELEQDLDHLKDEKEKLLKE 526
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.126 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,782,152
Number of Sequences: 37866
Number of extensions: 541802
Number of successful extensions: 4653
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 195
Number of HSP's successfully gapped in prelim test: 380
Number of HSP's that attempted gapping in prelim test: 3703
Number of HSP's gapped (non-prelim): 1264
length of query: 261
length of database: 18,247,518
effective HSP length: 100
effective length of query: 161
effective length of database: 14,460,918
effective search space: 2328207798
effective search space used: 2328207798
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.