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Search of human proteins with 140161498
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|140161498 hypothetical protein LOC23281 isoform a [Homo
sapiens]
(1379 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|140161498 hypothetical protein LOC23281 isoform a [Homo sapiens] 2730 0.0
gi|57768564 hypothetical protein LOC23281 isoform b [Homo sapiens] 640 0.0
gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo sap... 238 2e-62
gi|17865632 mitochondrial tumor suppressor 1 isoform 5 [Homo sap... 238 3e-62
gi|50348617 mitochondrial tumor suppressor 1 isoform 2 [Homo sap... 238 4e-62
gi|50348626 mitochondrial tumor suppressor 1 isoform 4 [Homo sap... 238 4e-62
gi|45935391 coiled-coil domain containing 69 [Homo sapiens] 137 7e-32
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 79 3e-14
gi|221139761 zinc finger protein 853 [Homo sapiens] 75 3e-13
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 74 1e-12
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 74 1e-12
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 74 1e-12
gi|82880656 coiled-coil domain containing 46 isoform a [Homo sap... 73 2e-12
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 73 2e-12
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 73 2e-12
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 73 2e-12
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 73 2e-12
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 73 2e-12
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 73 2e-12
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 73 2e-12
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 73 2e-12
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 72 4e-12
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 72 5e-12
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 72 5e-12
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 70 1e-11
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 70 1e-11
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 70 1e-11
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 70 1e-11
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 70 1e-11
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 70 1e-11
>gi|140161498 hypothetical protein LOC23281 isoform a [Homo sapiens]
Length = 1379
Score = 2730 bits (7077), Expect = 0.0
Identities = 1379/1379 (100%), Positives = 1379/1379 (100%)
Query: 1 MASSPTKGLTMSVPVAPKKSCYTQLRDNRNAARNNNESILSLGDTNANQIMLEVSSSHDE 60
MASSPTKGLTMSVPVAPKKSCYTQLRDNRNAARNNNESILSLGDTNANQIMLEVSSSHDE
Sbjct: 1 MASSPTKGLTMSVPVAPKKSCYTQLRDNRNAARNNNESILSLGDTNANQIMLEVSSSHDE 60
Query: 61 SKTCDLGDEIGNTNSSEPENRTHFHKEFHQLQGFGKGSQAGSASLKDFRLSSTIQRELNE 120
SKTCDLGDEIGNTNSSEPENRTHFHKEFHQLQGFGKGSQAGSASLKDFRLSSTIQRELNE
Sbjct: 61 SKTCDLGDEIGNTNSSEPENRTHFHKEFHQLQGFGKGSQAGSASLKDFRLSSTIQRELNE 120
Query: 121 EHTVERGTDSLQTTRSIQGPSLSSWRNVMSEASLDVLAKRDAEIPRHVPKDKLAKTLDNE 180
EHTVERGTDSLQTTRSIQGPSLSSWRNVMSEASLDVLAKRDAEIPRHVPKDKLAKTLDNE
Sbjct: 121 EHTVERGTDSLQTTRSIQGPSLSSWRNVMSEASLDVLAKRDAEIPRHVPKDKLAKTLDNE 180
Query: 181 ELRRHSLERASSSVAAVGSLTPQHPQPLSLDSREARGQIPGGGEGPQKTLPDHAVPAAFP 240
ELRRHSLERASSSVAAVGSLTPQHPQPLSLDSREARGQIPGGGEGPQKTLPDHAVPAAFP
Sbjct: 181 ELRRHSLERASSSVAAVGSLTPQHPQPLSLDSREARGQIPGGGEGPQKTLPDHAVPAAFP 240
Query: 241 ATDSTSEGKSVRHPKPSTSESKQSTPSETQTVGAHVLQVCSEHTSHSAHPEPALNLTLAS 300
ATDSTSEGKSVRHPKPSTSESKQSTPSETQTVGAHVLQVCSEHTSHSAHPEPALNLTLAS
Sbjct: 241 ATDSTSEGKSVRHPKPSTSESKQSTPSETQTVGAHVLQVCSEHTSHSAHPEPALNLTLAS 300
Query: 301 KEIPSKLEAQLGQGKGEAKLDLKYVPPRRVEQEGKAAQEGYLGCHKEENLSALEGRDPCG 360
KEIPSKLEAQLGQGKGEAKLDLKYVPPRRVEQEGKAAQEGYLGCHKEENLSALEGRDPCG
Sbjct: 301 KEIPSKLEAQLGQGKGEAKLDLKYVPPRRVEQEGKAAQEGYLGCHKEENLSALEGRDPCG 360
Query: 361 EAHPEATDALGHLLNSDLHHLGVGRGNCEEKRGVNPGEQDSLHTTPKQGSASLGGADNQP 420
EAHPEATDALGHLLNSDLHHLGVGRGNCEEKRGVNPGEQDSLHTTPKQGSASLGGADNQP
Sbjct: 361 EAHPEATDALGHLLNSDLHHLGVGRGNCEEKRGVNPGEQDSLHTTPKQGSASLGGADNQP 420
Query: 421 TGKISPCAGEKLGERTSSSFSPGDSHVAFIPNNLTDSKPLDVIEEERRLGSGNKDSVMVL 480
TGKISPCAGEKLGERTSSSFSPGDSHVAFIPNNLTDSKPLDVIEEERRLGSGNKDSVMVL
Sbjct: 421 TGKISPCAGEKLGERTSSSFSPGDSHVAFIPNNLTDSKPLDVIEEERRLGSGNKDSVMVL 480
Query: 481 VFNPSVGENKTEVPEPLDPQSGRSEARESKEVTTSVAENRNLLENADKIESTSARADSVL 540
VFNPSVGENKTEVPEPLDPQSGRSEARESKEVTTSVAENRNLLENADKIESTSARADSVL
Sbjct: 481 VFNPSVGENKTEVPEPLDPQSGRSEARESKEVTTSVAENRNLLENADKIESTSARADSVL 540
Query: 541 NIPAPLHPETTVNMTYQPTTPSSSFQDVSVFGMDAGSPLVVPPPTDSARLLNTSPKVPDK 600
NIPAPLHPETTVNMTYQPTTPSSSFQDVSVFGMDAGSPLVVPPPTDSARLLNTSPKVPDK
Sbjct: 541 NIPAPLHPETTVNMTYQPTTPSSSFQDVSVFGMDAGSPLVVPPPTDSARLLNTSPKVPDK 600
Query: 601 NTCPSGIPKPVFTHSKDTPSSQEGMENYQVEKTEERTETKPIIMPKPKHVRPKIITYIRR 660
NTCPSGIPKPVFTHSKDTPSSQEGMENYQVEKTEERTETKPIIMPKPKHVRPKIITYIRR
Sbjct: 601 NTCPSGIPKPVFTHSKDTPSSQEGMENYQVEKTEERTETKPIIMPKPKHVRPKIITYIRR 660
Query: 661 NPQALGQVDASLVPVGLPYAPPTCTMPLPHEEKAAGGDLKPSANLYEKFKPDLQKPRVFS 720
NPQALGQVDASLVPVGLPYAPPTCTMPLPHEEKAAGGDLKPSANLYEKFKPDLQKPRVFS
Sbjct: 661 NPQALGQVDASLVPVGLPYAPPTCTMPLPHEEKAAGGDLKPSANLYEKFKPDLQKPRVFS 720
Query: 721 SGLMVSGIKPPGHPFSQMSEKFLQEVTDHPGKEEFCSPPYAHYEVPPTFYRSAMLLKPQL 780
SGLMVSGIKPPGHPFSQMSEKFLQEVTDHPGKEEFCSPPYAHYEVPPTFYRSAMLLKPQL
Sbjct: 721 SGLMVSGIKPPGHPFSQMSEKFLQEVTDHPGKEEFCSPPYAHYEVPPTFYRSAMLLKPQL 780
Query: 781 GLGAMSRLPSAKSRILIASQRSSASAIHPPGPITTATSLYSSDPSADLKKASSSNAAKSN 840
GLGAMSRLPSAKSRILIASQRSSASAIHPPGPITTATSLYSSDPSADLKKASSSNAAKSN
Sbjct: 781 GLGAMSRLPSAKSRILIASQRSSASAIHPPGPITTATSLYSSDPSADLKKASSSNAAKSN 840
Query: 841 LPKSGLRPPGYSRLPAAKLAAFGFVRSSSVSSVSSTQSGDSAQPEQGRPATRSTFGNEEQ 900
LPKSGLRPPGYSRLPAAKLAAFGFVRSSSVSSVSSTQSGDSAQPEQGRPATRSTFGNEEQ
Sbjct: 841 LPKSGLRPPGYSRLPAAKLAAFGFVRSSSVSSVSSTQSGDSAQPEQGRPATRSTFGNEEQ 900
Query: 901 PVLKASLPSKDTPKGAGRVAPPASSSVTAPRRSLLPAPKSTSTPAGTKKDAQKDQDTNKP 960
PVLKASLPSKDTPKGAGRVAPPASSSVTAPRRSLLPAPKSTSTPAGTKKDAQKDQDTNKP
Sbjct: 901 PVLKASLPSKDTPKGAGRVAPPASSSVTAPRRSLLPAPKSTSTPAGTKKDAQKDQDTNKP 960
Query: 961 AVSSPKRVAASTTKLHSPGYPKQRTAAARNGFPPKPDPQAREAERQLVLRLKERCEQQTR 1020
AVSSPKRVAASTTKLHSPGYPKQRTAAARNGFPPKPDPQAREAERQLVLRLKERCEQQTR
Sbjct: 961 AVSSPKRVAASTTKLHSPGYPKQRTAAARNGFPPKPDPQAREAERQLVLRLKERCEQQTR 1020
Query: 1021 QLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEKELSIELANIRDEVAFHTAKCEK 1080
QLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEKELSIELANIRDEVAFHTAKCEK
Sbjct: 1021 QLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEKELSIELANIRDEVAFHTAKCEK 1080
Query: 1081 LQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQH 1140
LQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQH
Sbjct: 1081 LQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQH 1140
Query: 1141 QEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKLRL 1200
QEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKLRL
Sbjct: 1141 QEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKLRL 1200
Query: 1201 SLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKN 1260
SLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKN
Sbjct: 1201 SLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKN 1260
Query: 1261 QQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQE 1320
QQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQE
Sbjct: 1261 QQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQE 1320
Query: 1321 YVEKETQEKKRLSRTNEELLWKLQTGDPTSPIKLSPTSPVYRGSSSGPSSPARVSTTPR 1379
YVEKETQEKKRLSRTNEELLWKLQTGDPTSPIKLSPTSPVYRGSSSGPSSPARVSTTPR
Sbjct: 1321 YVEKETQEKKRLSRTNEELLWKLQTGDPTSPIKLSPTSPVYRGSSSGPSSPARVSTTPR 1379
>gi|57768564 hypothetical protein LOC23281 isoform b [Homo sapiens]
Length = 348
Score = 640 bits (1652), Expect = 0.0
Identities = 330/332 (99%), Positives = 331/332 (99%)
Query: 1048 RKNESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAEL 1107
+ NESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAEL
Sbjct: 17 KTNESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAEL 76
Query: 1108 QELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAIT 1167
QELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAIT
Sbjct: 77 QELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAIT 136
Query: 1168 ILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEAL 1227
ILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEAL
Sbjct: 137 ILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEAL 196
Query: 1228 RKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKI 1287
RKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKI
Sbjct: 197 RKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKI 256
Query: 1288 QVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQTGD 1347
QVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQTGD
Sbjct: 257 QVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQTGD 316
Query: 1348 PTSPIKLSPTSPVYRGSSSGPSSPARVSTTPR 1379
PTSPIKLSPTSPVYRGSSSGPSSPARVSTTPR
Sbjct: 317 PTSPIKLSPTSPVYRGSSSGPSSPARVSTTPR 348
>gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo sapiens]
Length = 1270
Score = 238 bits (608), Expect = 2e-62
Identities = 179/577 (31%), Positives = 296/577 (51%), Gaps = 37/577 (6%)
Query: 814 TTATSLYSSDPSADLKKASSSNAAKSNLPKSGLRPPGYSRLPAAKLAAFG--FVRSSSVS 871
TT + S P + + ++ AK P S LR +R P+A A R SS
Sbjct: 704 TTTSGRNISKPDSCGLRQIAAPKAKVGPPVSCLRRNSDNRNPSADRAVSPQRIRRVSSSG 763
Query: 872 SVSSTQSGDSAQPEQGRPATRSTFGNEEQPVLKASLPSKDTPKGAGRVAPPASSSVTAPR 931
+S ++ S+ RP +S + + P L+ + TP A + ++ S +
Sbjct: 764 KPTSLKTAQSSWVNLPRPLPKSK-ASLKSPALRRT---GSTPSIASTHSELSTYSNNSGN 819
Query: 932 RSLLPAPKSTSTPAGTKKDAQKDQDTNKPAVSSPKRVAASTTKLHSPGYPKQRTAAARNG 991
+++ + PA ++ KP VS R K G ++ A N
Sbjct: 820 AAVIKYEEKPPKPAF--QNGSSGSFYLKPLVS---RAHVHLMKTPPKGPSRKNLFTALNA 874
Query: 992 -------------FPPKPDPQAREAERQLVL-RLKERCEQQTRQLGVAQGELKRAICGFD 1037
P+ P A E+ L L + K +CE Q+ + + L F+
Sbjct: 875 VEKSRQKNPRSLCIQPQTAPDALPPEKTLELTQYKTKCENQSGFILQLKQLLACGNTKFE 934
Query: 1038 ALAVATQHFFRKNESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVK 1097
AL V QH + E AL + K LS EL N+R E+ + CEKL+K + EL+ +E V+
Sbjct: 935 ALTVVIQHLLSEREEALKQHKTLSQELVNLRGELVTASTTCEKLEKARNELQTVYEAFVQ 994
Query: 1098 RLGWQQQAELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLE 1157
Q QAE E E RL+ + E +L++ + ++ + Q QEQ ++L A+H+ + LE
Sbjct: 995 ----QHQAEKTERENRLKEFYTREYEKLRDTYIEEAEKYKMQLQEQFDNLNAAHETSKLE 1050
Query: 1158 MENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLR 1217
+E +H+ + +L+ ++ + E+ HE+EKK LE+ + + SL+ Q++ L ++ +L
Sbjct: 1051 IEASHSEKLELLKKAYEASLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALN 1110
Query: 1218 DRARRFEEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLA 1277
++ + E+ ++ E+ + +LE++++SLK VLE+KN+++H+Q+ K++++EKL
Sbjct: 1111 EKLKSEEQ--KRRAREKANLKNPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKLV 1168
Query: 1278 EKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNE 1337
+ N L +K++ QQ+NE+LKAR+D++ ++RQLS E A LQE +EKE++ KRLS NE
Sbjct: 1169 DNNTALVDKLKRFQQENEELKARMDKHMAISRQLSTEQAVLQESLEKESKVNKRLSMENE 1228
Query: 1338 ELLWKLQTGDPTSPIKLSPTSPVY-----RGSSSGPS 1369
ELLWKL GD SP K SPTS R S S PS
Sbjct: 1229 ELLWKLHNGDLCSP-KRSPTSSAIPLQSPRNSGSFPS 1264
>gi|17865632 mitochondrial tumor suppressor 1 isoform 5 [Homo sapiens]
Length = 436
Score = 238 bits (607), Expect = 3e-62
Identities = 145/411 (35%), Positives = 238/411 (57%), Gaps = 14/411 (3%)
Query: 965 PKRVAASTTKLHSPGYPKQRTAAARNGFPPKPDPQAREAERQLVL-RLKERCEQQTRQLG 1023
P ST H+ +Q+ + P+ P A E+ L L + K +CE Q+ +
Sbjct: 28 PSGFRRSTVVFHTVEKSRQKNPRSLC-IQPQTAPDALPPEKTLELTQYKTKCENQSGFIL 86
Query: 1024 VAQGELKRAICGFDALAVATQHFFRKNESALVKEKELSIELANIRDEVAFHTAKCEKLQK 1083
+ L F+AL V QH + E AL + K LS EL N+R E+ + CEKL+K
Sbjct: 87 QLKQLLACGNTKFEALTVVIQHLLSEREEALKQHKTLSQELVNLRGELVTASTTCEKLEK 146
Query: 1084 EKEELERRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQ 1143
+ EL+ +E V+ Q QAE E E RL+ + E +L++ + ++ + Q QEQ
Sbjct: 147 ARNELQTVYEAFVQ----QHQAEKTERENRLKEFYTREYEKLRDTYIEEAEKYKMQLQEQ 202
Query: 1144 VEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQ 1203
++L A+H+ + LE+E +H+ + +L+ ++ + E+ HE+EKK LE+ + + SL+
Sbjct: 203 FDNLNAAHETSKLEIEASHSEKLELLKKAYEASLSEIKKGHEIEKKSLEDLLSEKQESLE 262
Query: 1204 DQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQI 1263
Q++ L ++ +L ++ + E+ ++ E+ + +LE++++SLK VLE+KN+++
Sbjct: 263 KQINDLKSENDALNEKLKSEEQ--KRRAREKANLKNPQIMYLEQELESLKAVLEIKNEKL 320
Query: 1264 HEQEKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVE 1323
H+Q+ K++++EKL + N L +K++ QQ+NE+LKAR+D++ ++RQLS E A LQE +E
Sbjct: 321 HQQDIKLMKMEKLVDNNTALVDKLKRFQQENEELKARMDKHMAISRQLSTEQAVLQESLE 380
Query: 1324 KETQEKKRLSRTNEELLWKLQTGDPTSPIKLSPTSPVY-----RGSSSGPS 1369
KE++ KRLS NEELLWKL GD SP K SPTS R S S PS
Sbjct: 381 KESKVNKRLSMENEELLWKLHNGDLCSP-KRSPTSSAIPLQSPRNSGSFPS 430
>gi|50348617 mitochondrial tumor suppressor 1 isoform 2 [Homo sapiens]
Length = 1216
Score = 238 bits (606), Expect = 4e-62
Identities = 140/382 (36%), Positives = 229/382 (59%), Gaps = 13/382 (3%)
Query: 994 PKPDPQAREAERQLVL-RLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNES 1052
P+ P A E+ L L + K +CE Q+ + + L F+AL V QH + E
Sbjct: 836 PQTAPDALPPEKTLELTQYKTKCENQSGFILQLKQLLACGNTKFEALTVVIQHLLSEREE 895
Query: 1053 ALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEE 1112
AL + K LS EL N+R E+ + CEKL+K + EL+ +E V+ Q QAE E E
Sbjct: 896 ALKQHKTLSQELVNLRGELVTASTTCEKLEKARNELQTVYEAFVQ----QHQAEKTEREN 951
Query: 1113 RLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDD 1172
RL+ + E +L++ + ++ + Q QEQ ++L A+H+ + LE+E +H+ + +L+
Sbjct: 952 RLKEFYTREYEKLRDTYIEEAEKYKMQLQEQFDNLNAAHETSKLEIEASHSEKLELLKKA 1011
Query: 1173 HDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTE 1232
++ + E+ HE+EKK LE+ + + SL+ Q++ L ++ +L ++ + E+ ++
Sbjct: 1012 YEASLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALNEKLKSEEQ--KRRAR 1069
Query: 1233 EQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQ 1292
E+ + +LE++++SLK VLE+KN+++H+Q+ K++++EKL + N L +K++ QQ
Sbjct: 1070 EKANLKNPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKLVDNNTALVDKLKRFQQ 1129
Query: 1293 QNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQTGDPTSPI 1352
+NE+LKAR+D++ ++RQLS E A LQE +EKE++ KRLS NEELLWKL GD SP
Sbjct: 1130 ENEELKARMDKHMAISRQLSTEQAVLQESLEKESKVNKRLSMENEELLWKLHNGDLCSP- 1188
Query: 1353 KLSPTSPVY-----RGSSSGPS 1369
K SPTS R S S PS
Sbjct: 1189 KRSPTSSAIPLQSPRNSGSFPS 1210
>gi|50348626 mitochondrial tumor suppressor 1 isoform 4 [Homo sapiens]
Length = 517
Score = 238 bits (606), Expect = 4e-62
Identities = 140/382 (36%), Positives = 229/382 (59%), Gaps = 13/382 (3%)
Query: 994 PKPDPQAREAERQLVL-RLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNES 1052
P+ P A E+ L L + K +CE Q+ + + L F+AL V QH + E
Sbjct: 137 PQTAPDALPPEKTLELTQYKTKCENQSGFILQLKQLLACGNTKFEALTVVIQHLLSEREE 196
Query: 1053 ALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEE 1112
AL + K LS EL N+R E+ + CEKL+K + EL+ +E V+ Q QAE E E
Sbjct: 197 ALKQHKTLSQELVNLRGELVTASTTCEKLEKARNELQTVYEAFVQ----QHQAEKTEREN 252
Query: 1113 RLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDD 1172
RL+ + E +L++ + ++ + Q QEQ ++L A+H+ + LE+E +H+ + +L+
Sbjct: 253 RLKEFYTREYEKLRDTYIEEAEKYKMQLQEQFDNLNAAHETSKLEIEASHSEKLELLKKA 312
Query: 1173 HDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTE 1232
++ + E+ HE+EKK LE+ + + SL+ Q++ L ++ +L ++ + E+ ++
Sbjct: 313 YEASLSEIKKGHEIEKKSLEDLLSEKQESLEKQINDLKSENDALNEKLKSEEQ--KRRAR 370
Query: 1233 EQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQ 1292
E+ + +LE++++SLK VLE+KN+++H+Q+ K++++EKL + N L +K++ QQ
Sbjct: 371 EKANLKNPQIMYLEQELESLKAVLEIKNEKLHQQDIKLMKMEKLVDNNTALVDKLKRFQQ 430
Query: 1293 QNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQTGDPTSPI 1352
+NE+LKAR+D++ ++RQLS E A LQE +EKE++ KRLS NEELLWKL GD SP
Sbjct: 431 ENEELKARMDKHMAISRQLSTEQAVLQESLEKESKVNKRLSMENEELLWKLHNGDLCSP- 489
Query: 1353 KLSPTSPVY-----RGSSSGPS 1369
K SPTS R S S PS
Sbjct: 490 KRSPTSSAIPLQSPRNSGSFPS 511
>gi|45935391 coiled-coil domain containing 69 [Homo sapiens]
Length = 296
Score = 137 bits (345), Expect = 7e-32
Identities = 84/282 (29%), Positives = 158/282 (56%), Gaps = 2/282 (0%)
Query: 1080 KLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQ 1139
+L K ++R E E ++ + EL L + + + E H + I Q
Sbjct: 7 RLSSCKPPKKKRQEPEPEQPPRPEPHELGPLNGDTAITVQLCASEEAERHQKDITRILQQ 66
Query: 1140 HQEQVEDLTASHDAAL-LEMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKL 1198
H+E+ + + LE+ + +L+ ++ +Q L +++E EK+ L +F +
Sbjct: 67 HEEEKKKWAQQVEKERELELRDRLDEQQRVLEGKNEEALQVLRASYEQEKEALTHSFREA 126
Query: 1199 RLSLQDQVDTLTFQSQSLRDRARRFEEA-LRKNTEEQLEIALAPYQHLEEDMKSLKQVLE 1257
+ Q+ +D LT Q ++ + + +R EE+ L +N ++ ++ +P Q E++++SL V+E
Sbjct: 127 SSTQQETIDRLTSQLEAFQAKMKRVEESILSRNYKKHIQDYGSPSQFWEQELESLHFVIE 186
Query: 1258 MKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENAN 1317
MKN++IHE +++++ +E + EKN+ILEEKI LQQ+NEDL R V++RQLSE+
Sbjct: 187 MKNERIHELDRRLILMETVKEKNLILEEKITTLQQENEDLHVRSRNQVVLSRQLSEDLLL 246
Query: 1318 LQEYVEKETQEKKRLSRTNEELLWKLQTGDPTSPIKLSPTSP 1359
+E +EKE Q +++L + EELL+++ + + L+P +P
Sbjct: 247 TREALEKEVQLRRQLQQEKEELLYRVLGANASPAFPLAPVTP 288
Score = 40.8 bits (94), Expect = 0.009
Identities = 65/305 (21%), Positives = 129/305 (42%), Gaps = 53/305 (17%)
Query: 973 TKLHSPGYPKQRTAAARNGFPPKPDPQAR---EAERQLVLRLKERCEQQTRQLGVAQGEL 1029
++L S PK++ PP+P+P + + ++L E + Q + +
Sbjct: 6 SRLSSCKPPKKKRQEPEPEQPPRPEPHELGPLNGDTAITVQLCASEEAERHQKDITR--- 62
Query: 1030 KRAICGFDALAVATQHFFRKNESALVKEKELSIELANIRDEV--AFHTAKCEKLQ----- 1082
+ QH K + A EKE +EL + DE E LQ
Sbjct: 63 -----------ILQQHEEEKKKWAQQVEKERELELRDRLDEQQRVLEGKNEEALQVLRAS 111
Query: 1083 --KEKEELERRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQH 1140
+EKE L F + QQ + L +L+ F+A+M R++E + +
Sbjct: 112 YEQEKEALTHSFREASS----TQQETIDRLTSQLE-AFQAKMKRVEES------ILSRNY 160
Query: 1141 QEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELEKK-ELEENFEKLR 1199
++ ++D + E+E+ H V + K + + HEL+++ L E ++
Sbjct: 161 KKHIQDYGSPSQFWEQELESLHFVI--------EMKNERI---HELDRRLILMETVKEKN 209
Query: 1200 LSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMK 1259
L L++++ TL +++ L R+R + L + E L L + LE++++ +Q+ + K
Sbjct: 210 LILEEKITTLQQENEDLHVRSRN-QVVLSRQLSEDL---LLTREALEKEVQLRRQLQQEK 265
Query: 1260 NQQIH 1264
+ ++
Sbjct: 266 EELLY 270
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens]
Length = 570
Score = 79.0 bits (193), Expect = 3e-14
Identities = 67/299 (22%), Positives = 147/299 (49%), Gaps = 22/299 (7%)
Query: 1044 QHFFRKNESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQ 1103
+ +R+ E +E+++ + IR++ + E++ EKEE RR E+ + W++
Sbjct: 288 EKMWRQEEKIQEREEKIQEQEEKIREQEE-KMRRQEEMMWEKEEKMRRQEEMM----WEK 342
Query: 1104 QAELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHT 1163
+ +++ELEE++ E E R QEE + IR Q + Q ++ A + E
Sbjct: 343 EEKIRELEEKMH---EQEKIREQEEKRQEEEKIREQEKRQEQE------AKMWRQEEKIR 393
Query: 1164 VAITILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRF 1223
Q++ + +E+M E + E EE + +Q+Q + + Q + +R++ ++
Sbjct: 394 E-----QEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKI 448
Query: 1224 EEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQ--IHEQEKKILELEK-LAEKN 1280
E K E++ + + E++ K +Q +M+ Q+ + QE+KI E EK + E+
Sbjct: 449 REQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQE 508
Query: 1281 IILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEEL 1339
+ E+ +++Q+Q E + + ++ ++ E+ ++ EK +++ RL + E++
Sbjct: 509 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKM 567
Score = 74.7 bits (182), Expect = 6e-13
Identities = 67/299 (22%), Positives = 142/299 (47%), Gaps = 31/299 (10%)
Query: 1048 RKNESA--LVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQA 1105
RK E A L+ +++L E ++ E+ +AK + Q E+ EL R + + W+Q+
Sbjct: 237 RKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQA-QVEENELWNRLNQQQEEKMWRQEE 295
Query: 1106 ELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQV---EDLTASHDAALLEMENNH 1162
++QE EE++Q Q E R QEE + + + +E++ E++ + + E+E
Sbjct: 296 KIQEREEKIQEQ--EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE-- 351
Query: 1163 TVAITILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARR 1222
K+ E E E+K EE + + Q+Q + Q + +R++ +
Sbjct: 352 -------------KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 398
Query: 1223 F--EEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKN 1280
+E + + EE++ EE+M+ ++ + + ++I EQEKKI E E+
Sbjct: 399 IREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEK---- 454
Query: 1281 IILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEEL 1339
+ E+ +++Q+Q E + + + ++ E+ ++ EK +++K++ E++
Sbjct: 455 --IREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKI 511
Score = 62.4 bits (150), Expect = 3e-09
Identities = 61/294 (20%), Positives = 141/294 (47%), Gaps = 22/294 (7%)
Query: 1004 ERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEKELSIE 1063
+ + + +E+ ++Q ++ + +++R + + + R+ E + +++E E
Sbjct: 293 QEEKIQEREEKIQEQEEKIREQEEKMRRQ----EEMMWEKEEKMRRQEEMMWEKEEKIRE 348
Query: 1064 LANIRDEVAFHTAKCEKLQKEKE--ELERRFEDEVKRLGWQQQAELQELEERLQLQFEAE 1121
L E + EK Q+E++ E E+R E E K W+Q+ +++E EE+++ Q E
Sbjct: 349 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM--WRQEEKIREQEEKIREQ-EEM 405
Query: 1122 MARLQEEHGDQLLSIRCQHQE--QVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQE 1179
M +E+ G+Q + Q +E + E+ + + E E Q++ + +E
Sbjct: 406 MQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIRE-----QEEKIREQEE 460
Query: 1180 LMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIAL 1239
+M E + E E + +Q+Q + + Q + +R++ ++ E K E++
Sbjct: 461 MMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE----- 515
Query: 1240 APYQHLEEDMKSLKQVLEMKNQQIHEQEKKI-LELEKLAEKNIILEEKIQVLQQ 1292
Q EE M ++ + + +++ EQE+K+ + EK+ E+ + L ++ + +Q+
Sbjct: 516 EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 43.5 bits (101), Expect = 0.001
Identities = 41/164 (25%), Positives = 75/164 (45%), Gaps = 23/164 (14%)
Query: 1185 ELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQH 1244
E E+K ++ E LR L+ QV T+ R T ++ E+ +A Y +
Sbjct: 96 EDEQKASHQHQEALRRELEAQVQTI------------------RILTCQKTELQMALY-Y 136
Query: 1245 LEEDMKSLKQVLEMKNQQIHEQEKKILELEK----LAEKNIILEEKIQVLQQQNEDLKAR 1300
+ +K L+ ++H+ K ELE+ +A + + I+ L ++ + L
Sbjct: 137 SQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLE 196
Query: 1301 IDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQ 1344
+ +NT+ +L E+NA LQE ++ EK + +EL KL+
Sbjct: 197 LYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLE 240
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 75.5 bits (184), Expect = 3e-13
Identities = 100/456 (21%), Positives = 196/456 (42%), Gaps = 68/456 (14%)
Query: 936 PAPKSTSTPAGTKKDAQKDQDTNKPAVSSPKRVAASTTKLHSPGYPKQRTAAARNGFPPK 995
P P + S +G + ++++ + SSP+R A S P + A P +
Sbjct: 37 PGPDTLSGGSGGSESQEEEEPQERN--SSPQRPAVSA--------PVGASEIAEETRPGQ 86
Query: 996 PDPQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALV 1055
+ Q ++ E+Q + + + Q QL Q L+ L Q ++ S L
Sbjct: 87 RELQLQQLEQQP----EPQQQPQHEQLQQPQPHLE--------LQQQPQQDGQQQLSQLQ 134
Query: 1056 KEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQ 1115
+EK S+ ++ E+ + ++LQ ++ + ++R + + ++L QQ E Q L+++ Q
Sbjct: 135 QEKHQSVHHQELKPELQLMHQQ-QQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQ 193
Query: 1116 LQFEAEMARLQEEHGDQLLSIRC----------QHQEQVEDLTASHDAALLEMENNHTVA 1165
LQ + + +L ++ +QL + Q Q+Q E L LL+ + +
Sbjct: 194 LQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQ--LQ 251
Query: 1166 ITILQDDHDHKVQELMSTH--ELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRF 1223
+LQ Q+L+ +L+++ L + E+L+ Q Q L Q Q + +
Sbjct: 252 QQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQ---QQQQQQLLQQQQEQLQQQQLQ 308
Query: 1224 EEALRKNTEEQLEIALAPYQ-HLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNII 1282
L EE++E+ L P E++++ +Q LE + + +QE++ L+L+
Sbjct: 309 PPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLK-------- 360
Query: 1283 LEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWK 1342
L+E++Q L+QQ E + +++Q V E L +E+ +
Sbjct: 361 LQEELQQLEQQLEQQQQQLEQQEVQLELTPVE-----------------LGAQQQEVQLE 403
Query: 1343 LQTGDPTSPIKLSPTSPVYRGSSSGPSSPARVSTTP 1378
L P ++L P + G ++ P +PA V P
Sbjct: 404 LTPVQPELQLELVPAAG--GGGAAVPGAPAAVVVAP 437
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 73.9 bits (180), Expect = 1e-12
Identities = 73/352 (20%), Positives = 169/352 (48%), Gaps = 23/352 (6%)
Query: 997 DPQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVK 1056
+ + RE E + + +E+ +Q + + +++R + + + R+ E + +
Sbjct: 320 EEKIREQEEK-IREQEEKMRRQEEMMWEKEEKMRRQ----EEMMWEKEEKMRRLEEMMWE 374
Query: 1057 EKELSIELANIRDEVAFHTAKCEKLQKEKE--ELERRFEDEVKRLGWQQQAELQELEERL 1114
++E EL E + EK Q+E++ E E+R E E K W+Q+ +++E EE++
Sbjct: 375 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM--WRQEEKIREQEEKI 432
Query: 1115 QLQFEAEMARLQEE-HGDQLLSIRCQHQEQVE-----DLTASHDAALLEMENNHTVAITI 1168
+ Q E +M R +E+ H + + + QEQ E + + + E H
Sbjct: 433 REQ-EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIR 491
Query: 1169 LQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALR 1228
Q++ + +E M E + +E EE + +++Q + + Q + +R++ +E
Sbjct: 492 KQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEE 551
Query: 1229 KNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELE-KLAEKNIILEEKI 1287
K E++ ++ +E M+ ++ + + ++I EQ++KI E E K+ E+ + E+
Sbjct: 552 KMGEQEEKM------QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQE 605
Query: 1288 QVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEEL 1339
+++Q+Q E + + ++ ++ E+ ++ EK +++ RL + E++
Sbjct: 606 EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 657
Score = 71.2 bits (173), Expect = 6e-12
Identities = 71/362 (19%), Positives = 163/362 (45%), Gaps = 35/362 (9%)
Query: 999 QAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEK 1058
QA+ E +L RL ++ E++ + E + I + + R+ E + +++
Sbjct: 282 QAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE 341
Query: 1059 ELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQF 1118
E+ E ++E + E++ EKEE RR E+ + W+++ +++ELEE++
Sbjct: 342 EMMWE----KEE---KMRRQEEMMWEKEEKMRRLEEMM----WEKEEKIRELEEKMH--- 387
Query: 1119 EAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQ 1178
E E R QEE + IR Q + Q ++ + + + K+
Sbjct: 388 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 447
Query: 1179 ELMSTHELEKKELEENF----EKLRLS---------------LQDQVDTLTFQSQSLRDR 1219
E E EK++ +E EK+R ++ Q + + Q + + D+
Sbjct: 448 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQ 507
Query: 1220 ARRFEEALRK--NTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLA 1277
+ E K EE++ + EE ++ +++++ + +++ EQE+K+ E EK+
Sbjct: 508 EEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMR 567
Query: 1278 EKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNE 1337
+ + E+ + +++Q E ++ + ++ ++ E+ +QE EK ++++++ E
Sbjct: 568 RQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 627
Query: 1338 EL 1339
++
Sbjct: 628 KM 629
Score = 56.6 bits (135), Expect = 2e-07
Identities = 58/257 (22%), Positives = 126/257 (49%), Gaps = 24/257 (9%)
Query: 1048 RKNESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAEL 1107
R+ E + +++E E IR+E EK Q+++E + + + W+Q+ ++
Sbjct: 433 REQEKKMWRQEEKIHEQEKIREE--------EKRQEQEEMWRQEEKIREQEEIWRQKEKM 484
Query: 1108 QELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQE--QVEDLTASHDAALLEMENNHTVA 1165
E +E+++ Q E ++ R +E+ DQ IR Q ++ + E+ + + E E
Sbjct: 485 HE-QEKIRKQ-EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQ 542
Query: 1166 ITILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEE 1225
++Q+ + ++ E EK +E EK+R +Q + + Q + +R++ + E
Sbjct: 543 EEMMQEQEEKMGEQEEKMQEQEKMRRQE--EKIR----EQEEKIREQKEKIREQEEKIWE 596
Query: 1226 ALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKIL-ELEKLAEKNIILE 1284
K E++ + Q EE M ++ + + +++ EQE+K+ + EK+ E+ + L
Sbjct: 597 QEEKIREQEEMM-----QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 651
Query: 1285 EKIQVLQQQNEDLKARI 1301
++ + +Q+ E L+A I
Sbjct: 652 QQEEKMQEHQEHLEAAI 668
Score = 44.3 bits (103), Expect = 8e-04
Identities = 60/275 (21%), Positives = 119/275 (43%), Gaps = 56/275 (20%)
Query: 1070 EVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQ--LQFEAEMARLQE 1127
E HT + QK + ++ + + Q + E ++L RL +F E+ E
Sbjct: 126 EAQVHTIRILTCQKTELQMALYYSQHAVK---QLEGEARDLISRLHDSWKFAGEL----E 178
Query: 1128 EHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELE 1187
+ + + + + +E+LT DA LE+ N T+ L++ + K+QE + E E
Sbjct: 179 QALSAVATQKKKADRYIEELTKERDALSLELYRN-TITDEELKEKNA-KLQEKLQLVESE 236
Query: 1188 KKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEE 1247
K E++ N ++L+ R+ E A ++QL+ A HL +
Sbjct: 237 KSEIQLNVKELK---------------------RKLERAKLLLPQQQLQ---AEADHLGK 272
Query: 1248 DMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQNTVV 1307
+++S+ L+ Q+ E E ++ EK EEKIQ +++
Sbjct: 273 ELQSVSAKLQA---QVEENELWNRLNQQQEEKMWRQEEKIQEWEEK-------------- 315
Query: 1308 TRQLSEENANLQEYVEKETQEKKRLSRTNEELLWK 1342
+ E+ ++E EK ++++++ R EE++W+
Sbjct: 316 ---IQEQEEKIREQEEKIREQEEKMRR-QEEMMWE 346
Score = 43.1 bits (100), Expect = 0.002
Identities = 41/164 (25%), Positives = 75/164 (45%), Gaps = 23/164 (14%)
Query: 1185 ELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQH 1244
E E+K ++ E LR L+ QV T+ R T ++ E+ +A Y +
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTI------------------RILTCQKTELQMALY-Y 148
Query: 1245 LEEDMKSLKQVLEMKNQQIHEQEKKILELEK----LAEKNIILEEKIQVLQQQNEDLKAR 1300
+ +K L+ ++H+ K ELE+ +A + + I+ L ++ + L
Sbjct: 149 SQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLE 208
Query: 1301 IDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQ 1344
+ +NT+ +L E+NA LQE ++ EK + +EL KL+
Sbjct: 209 LYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLE 252
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 73.9 bits (180), Expect = 1e-12
Identities = 97/385 (25%), Positives = 174/385 (45%), Gaps = 48/385 (12%)
Query: 995 KPDPQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESAL 1054
KP Q E +++ + +E + + +QL + +A Q + L
Sbjct: 835 KPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQL-----QEQL 889
Query: 1055 VKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQ------QAELQ 1108
E EL E +R + TAK ++L++ +LE R E+E +R Q Q +Q
Sbjct: 890 QAETELCAEAEELRARL---TAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQ 946
Query: 1109 ELEERLQ-------------LQFEAEMARLQEEH---GDQLLSIRCQHQEQVEDLTASHD 1152
ELEE+L+ + EA++ +L+EE DQ + + ++ +ED A
Sbjct: 947 ELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKL-AKEKKLLEDRIAEFT 1005
Query: 1153 AALLEMENNHTVAITILQDDHDHKV---QELMSTHELEKKELEENFEKLR---LSLQDQV 1206
L E E + ++ L++ H+ + +E + E +++ELE+ KL L DQ+
Sbjct: 1006 TNLTE-EEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQI 1064
Query: 1207 DTLTFQSQSLRDRARRFEE----ALRKNTEE--QLEIALAPYQHLEEDMKSLKQVLEMKN 1260
L Q L+ + + EE AL + EE Q +AL + LE + L++ LE +
Sbjct: 1065 AELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
Query: 1261 QQIHEQEKKILEL-EKLAEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQ 1319
++ EK+ +L E+L LE+ + Q E L+++ +Q + ++ EE A
Sbjct: 1125 ASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQE-LRSKREQEVNILKKTLEEEAKTH 1183
Query: 1320 EYVEKETQEKKRLSRTNEELLWKLQ 1344
E +E ++K S+ EEL +L+
Sbjct: 1184 EAQIQEMRQKH--SQAVEELAEQLE 1206
Score = 62.4 bits (150), Expect = 3e-09
Identities = 86/370 (23%), Positives = 156/370 (42%), Gaps = 45/370 (12%)
Query: 1008 VLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEKELSIELANI 1067
+ L+ + + QL + EL+ A LA + +KN AL K +EL +++ +
Sbjct: 1064 IAELQAQIAELKMQLAKKEEELQAA------LARVEEEAAQKN-MALKKIRELESQISEL 1116
Query: 1068 RDEVAFHTAKCEKLQKEKEELERRFEDEVKRLG--WQQQAELQELEERLQLQFEAEMARL 1125
++++ A K +K+K +L E L A QEL + + + L
Sbjct: 1117 QEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTL 1176
Query: 1126 QEE---HGDQLLSIRCQHQEQVEDLT----------ASHDAALLEMEN------NHTVAI 1166
+EE H Q+ +R +H + VE+L A+ + A +EN N +
Sbjct: 1177 EEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVL 1236
Query: 1167 TILQDDHDHK-------VQELM---STHELEKKELEENFEKLRLSLQDQVDTLTFQSQSL 1216
+ D +HK +QEL + E + EL + KL++ L D V L QS S
Sbjct: 1237 LQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL-DNVTGLLSQSDSK 1295
Query: 1217 RDRARRFEEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKN---QQIHEQEKKILEL 1273
+ + AL ++ E+ + LKQV + KN +Q+ E+E+ L
Sbjct: 1296 SSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNL 1355
Query: 1274 EKLAEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLS 1333
EK + L ++ ++++ ED ++ V R+L ++ L + E++ +L
Sbjct: 1356 EK---QIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLE 1412
Query: 1334 RTNEELLWKL 1343
+T L +L
Sbjct: 1413 KTKTRLQQEL 1422
Score = 55.8 bits (133), Expect = 3e-07
Identities = 66/311 (21%), Positives = 138/311 (44%), Gaps = 29/311 (9%)
Query: 1051 ESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQ-E 1109
E+A +++L +L + A +KL+K K L++ +D + L Q+Q+ E
Sbjct: 1381 ETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLE 1440
Query: 1110 LEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITIL 1169
+++ Q AE + ++ ++ R + + + ++ A A LE + L
Sbjct: 1441 KKQKKFDQLLAEEKTISAKYAEE--RDRAEAEAREKETKALSLARALEEAMEQKAELERL 1498
Query: 1170 QDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRK 1229
++++LMS+ + K + E EK + +L+ QV+ + Q + L D + E+A
Sbjct: 1499 NKQFRTEMEDLMSSKDDVGKSVHE-LEKSKRALEQQVEEMKTQLEELEDELQATEDA--- 1554
Query: 1230 NTEEQLEIAL-APYQHLEEDMKSLKQVLEMKNQQIHEQEKKI-LELEKLAEKNIILEEKI 1287
+ +LE+ L A E D++ + E K +Q+ Q +++ ELE ++ +
Sbjct: 1555 --KLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAAR 1612
Query: 1288 QVLQQQNEDLKARID------------------QNTVVTRQLSEENANLQEYVEKETQEK 1329
+ L+ +DL+A ID Q R+L + A+ +E + + + +
Sbjct: 1613 KKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENE 1672
Query: 1330 KRLSRTNEELL 1340
K+L E++
Sbjct: 1673 KKLKSMEAEMI 1683
Score = 52.8 bits (125), Expect = 2e-06
Identities = 76/342 (22%), Positives = 142/342 (41%), Gaps = 45/342 (13%)
Query: 1048 RKNESALVKEKEL-SIELANIRDEVAFHTAKCEKLQK----EKEELERRFED-------- 1094
R A +EKE ++ LA +E A+ E+L K E E+L +D
Sbjct: 1464 RDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHEL 1523
Query: 1095 EVKRLGWQQQAE-----LQELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTA 1149
E + +QQ E L+ELE+ LQ E A+L+ E Q + + + Q D +
Sbjct: 1524 EKSKRALEQQVEEMKTQLEELEDELQA---TEDAKLRLEVNLQAMKAQFERDLQGRDEQS 1580
Query: 1150 SHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELEK--KELEENFEKLRLSLQDQVD 1207
L + A L+D+ + + + +LE K+LE + + + + +
Sbjct: 1581 EEKKKQLVRQVREMEAE--LEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIK 1638
Query: 1208 TLTFQSQSLRDRARRFEE---------ALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEM 1258
L ++D R ++ A K E++L+ A L+E++ + ++
Sbjct: 1639 QLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQ 1698
Query: 1259 KNQQIHEQEKKI----------LELEKLAEKNII-LEEKIQVLQQQNEDLKARIDQNTVV 1307
Q+ E +I LE ++ E I LEE+++ Q E + R+ + +
Sbjct: 1699 AQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQ 1758
Query: 1308 TRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQTGDPT 1349
Q++ + + + +K +++L R N+EL KLQ + T
Sbjct: 1759 IDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGT 1800
Score = 51.6 bits (122), Expect = 5e-06
Identities = 75/384 (19%), Positives = 159/384 (41%), Gaps = 29/384 (7%)
Query: 948 KKDAQ-KDQDTNKPAVSSPKRVAASTTKLHSPGYPKQRTAAARNGFPPKPDPQAREAERQ 1006
++D Q +D+ + + ++V +L + AAR K + ++ E
Sbjct: 1570 ERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARK----KLEMDLKDLEAH 1625
Query: 1007 LVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEKELSIELAN 1066
+ K R ++ +QL Q ++K + D + + + + K K + E+
Sbjct: 1626 IDSANKNR-DEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQ 1684
Query: 1067 IRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQ 1126
+++E+A + Q+E++EL DE+ + L+E + RL+ + L+
Sbjct: 1685 LQEELAAAERAKRQAQQERDEL----ADEIANSSGKGALALEE-KRRLEARIAQLEEELE 1739
Query: 1127 EEHGD-QLLSIRCQHQE-QVEDLTASHDAALLEMENNHTVAITILQDDHDHKV--QELMS 1182
EE G+ +L++ R + Q++ + + + N + + + + KV QE+
Sbjct: 1740 EEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEG 1799
Query: 1183 THELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEAL----------RKNTE 1232
T + + K E L++Q+D T + Q+ + RR E+ L R+N E
Sbjct: 1800 TVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAE 1859
Query: 1233 EQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQ 1292
+ + A L++ + L++ E + + K ELE E + ++ L+
Sbjct: 1860 QYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKN 1919
Query: 1293 QNEDLKARIDQNTVVTRQLSEENA 1316
+ R D VV R+++ + A
Sbjct: 1920 K----LRRGDLPFVVPRRMARKGA 1939
Score = 35.8 bits (81), Expect = 0.29
Identities = 39/137 (28%), Positives = 62/137 (45%), Gaps = 9/137 (6%)
Query: 1222 RFEEALRKNTEEQLEIA---LAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAE 1278
R EE + EE +++ LA L E M++L+ L + Q+ EQ + EL AE
Sbjct: 842 RQEEEMMAKEEELVKVREKQLAAENRLTE-METLQSQLMAEKLQLQEQLQAETELCAEAE 900
Query: 1279 K-NIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNE 1337
+ L K Q L++ DL+AR+++ + L E +Q+ + QE + E
Sbjct: 901 ELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNI----QELEEQLEEEE 956
Query: 1338 ELLWKLQTGDPTSPIKL 1354
KLQ T+ KL
Sbjct: 957 SARQKLQLEKVTTEAKL 973
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 73.6 bits (179), Expect = 1e-12
Identities = 86/352 (24%), Positives = 157/352 (44%), Gaps = 29/352 (8%)
Query: 1002 EAERQLVL--RLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEKE 1059
E +RQL +E+ E + + L +A+ L + G +ATQ ++ L+ +K
Sbjct: 915 EVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKE-LMAQKL 973
Query: 1060 LSIEL---ANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQL 1116
+ E A++R++ A H ++LQ+EKE R E E +L Q Q E +EL RL+
Sbjct: 974 VQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEA 1033
Query: 1117 QFE---AEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLE--MENNHTVAITILQD 1171
+ E E+A LQ+E + LL + Q Q L S AL E M H++A L
Sbjct: 1034 EKEELSEEIAALQQERDEGLLLAESEKQ-QALSLKESEKTALSEKLMGTRHSLATISL-- 1090
Query: 1172 DHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNT 1231
+ + + ++ S E ++ + +LR + + +Q + RR +E R +
Sbjct: 1091 EMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEV----RRLQEQAR-DL 1145
Query: 1232 EEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQ 1291
+Q + L + L ++ L+ + +++ E ++K+ E +E +V +
Sbjct: 1146 GKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRE----------SQEGREVQR 1195
Query: 1292 QQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKL 1343
Q+ +L+ + + L N L+ V+K E+ L NE+ KL
Sbjct: 1196 QEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKL 1247
Score = 60.1 bits (144), Expect = 1e-08
Identities = 150/702 (21%), Positives = 258/702 (36%), Gaps = 145/702 (20%)
Query: 780 LGLGAMSRLPSAKSRILIASQRSSASAIHPP--GPITTATSLYSSDPSADLKKASSS--- 834
LGL RL +++ + Q + + + L +DL KA S
Sbjct: 340 LGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARV 399
Query: 835 ---NAAKSNLPKSGLRPPGYSRLPAAKLAAFGFVRSSSVSSVSSTQSGDSAQPEQGRPAT 891
A L K L ++ KL A +R +++ T+ G+ Q + R
Sbjct: 400 TELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAALE-TEDGEGLQ-QTLRDLA 457
Query: 892 RSTFGNEEQPV-LKASLPSKDTPKGAGR-------VAPPASSSV---TAPRRSLLPAPKS 940
++ + E V L S + D G+ R +PP SS +PRR PA
Sbjct: 458 QAVLSDSESGVQLSGSERTADASNGSLRGLSGQRTPSPPRRSSPGRGRSPRRGPSPACSD 517
Query: 941 TSTPA----GTKKDAQKDQDTNKPAVSSP-------KRVAASTTKLHSPGYPKQRTAAAR 989
+ST A K + QD +S K+++ S ++ + QR
Sbjct: 518 SSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKT 577
Query: 990 NGFPPKPDPQAREAER-------------------QLVLRLKERCEQQTRQLGVAQGELK 1030
+G + RE +R Q+ + E Q+ +L AQ EL+
Sbjct: 578 DGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELR 637
Query: 1031 R-----------AICGFDALAVATQHFFRKNESALVKEKELSIELANIRDEVAFHTAKCE 1079
R A+ + + R+ E K L+ EL +R+ ++ T + +
Sbjct: 638 RQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRD 697
Query: 1080 KLQKEKEEL------------------------ERRFEDEVKRLGWQQQAELQELEE--R 1113
LQ EK E+ E +D + +L ++ Q+ + R
Sbjct: 698 MLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNR 757
Query: 1114 LQLQFEAEMARLQ--EEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVA------ 1165
L Q E E + LQ + +Q ++ + QE++E+L + A +E + VA
Sbjct: 758 LVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEA 817
Query: 1166 ----ITILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRAR 1221
+ L+ + ++QE ++ + E+ E+ R Q QV+ L ++ A+
Sbjct: 818 LEQQLPTLRHERS-QLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAK 876
Query: 1222 RF------------------EEALRKNTE-EQLEIALAPYQHLEEDMKSLKQVLE----- 1257
EEA R E E LE +L Q +++ ++ LE
Sbjct: 877 EHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQA 936
Query: 1258 --------------MKNQQIHEQEKKILELEKLAEKNIILEEKIQV-LQQQ----NEDLK 1298
++ Q I QEK L+ E +A+K + E + Q L++Q EDL+
Sbjct: 937 LLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQ 996
Query: 1299 ARIDQNTVVTRQLSEENANLQEYVEKETQE-KKRLSRTNEEL 1339
+ R+L E A LQ +++E +E RL EEL
Sbjct: 997 RLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEEL 1038
Score = 50.4 bits (119), Expect = 1e-05
Identities = 93/429 (21%), Positives = 169/429 (39%), Gaps = 85/429 (19%)
Query: 936 PAPKSTSTPAGTKKDAQKDQDTNKPAVSSPKRVAASTTKLHSPGYPKQRTAAARNGFPPK 995
P+P P +DA PA S + + + +T SPG A + P
Sbjct: 1450 PSPAPRPVPGSPARDA--------PAEGSGEGLNSPSTLECSPGSQPPSPGPATSPASPD 1501
Query: 996 PDPQA-REAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESAL 1054
DP+A R A R+ + L+ AQ R+ +
Sbjct: 1502 LDPEAVRGALREFLQELRS-----------AQ---------------------RERDELR 1529
Query: 1055 VKEKELSIELANIRDEVAFHTAKCEKLQK---EKEELERRFEDEVKRLGWQQQAELQELE 1111
+ L+ +LA + E T++ +LQK E EE R + + + QAEL E
Sbjct: 1530 TQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGV----QAELALQE 1585
Query: 1112 ERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQD 1171
E ++ A L DQ+ ++ Q +L AS + + +M+ N T L+
Sbjct: 1586 ESVRRSERERRATL-----DQVATLERSLQATESELRASQEK-ISKMKANETK----LEG 1635
Query: 1172 DHDHKVQELMSTHE-------LEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFE 1224
D +++E++ E L+++ LE ++ RL L D+ Q+Q+L+DR +
Sbjct: 1636 DK-RRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDR----EAQAQALQDRVDSLQ 1690
Query: 1225 EALRKN---------TEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEK 1275
+ + T E+L ALA +EE +L+ + + + + L
Sbjct: 1691 RQVADSEVKAGTLQLTVERLNGALAK---VEESEGALRDKVRGLTEALAQSSAS---LNS 1744
Query: 1276 LAEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRT 1335
+KN+ L++ + + + L+ R+D + +++++L E V+ E L
Sbjct: 1745 TRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQ 1804
Query: 1336 NEELLWKLQ 1344
E +LQ
Sbjct: 1805 RVEAEGQLQ 1813
Score = 47.0 bits (110), Expect = 1e-04
Identities = 88/460 (19%), Positives = 191/460 (41%), Gaps = 65/460 (14%)
Query: 908 PSKDTPKGAGRVAPPASSSVTAPRRSLLPAPKSTSTPAGTKKD----------------- 950
P++D P + S++ S P+P ++PA D
Sbjct: 1461 PARDAPAEGSGEGLNSPSTLECSPGSQPPSPGPATSPASPDLDPEAVRGALREFLQELRS 1520
Query: 951 AQKDQDTNKPAVSSPKRVAASTTKLHSPGYPKQRTAAARNGFPPKPDPQAREAERQLVLR 1010
AQ+++D + S+ R A ++ +A +R K ++ EA R + R
Sbjct: 1521 AQRERDELRTQTSALNRQLAEMEA-------ERDSATSRARQLQKAVAESEEARRSVDGR 1573
Query: 1011 LKE-RCEQQTRQLGVAQGELKRA-----ICGFDALAVATQHFFRKNESALVK----EKEL 1060
L + E ++ V + E +R + + AT+ R ++ + K E +L
Sbjct: 1574 LSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKL 1633
Query: 1061 SIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQ-QQAELQELEERLQLQFE 1119
+ +++ + ++ KL+ ++ LE + RLG ++A+ Q L++R+ +
Sbjct: 1634 EGDKRRLKEVLDASESRTVKLELQRRSLEGELQRS--RLGLSDREAQAQALQDRVD-SLQ 1690
Query: 1120 AEMARLQEEHGDQLLSIR-----CQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHD 1174
++A + + G L++ E+ E L E + ++ +D +
Sbjct: 1691 RQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNL 1750
Query: 1175 HKVQELMSTHELEKKELEENFEKLRLSLQD---QVDTLTFQSQSLRDRARRFEEALRKNT 1231
H +Q+ ++ E +++ L+E + R +L + Q +L Q Q+LR
Sbjct: 1751 H-LQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRG------------- 1796
Query: 1232 EEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQ 1291
E+A Q +E + + L+Q+ E+ Q+ + + ++KL ++ +L+E++ LQ
Sbjct: 1797 ----EVADLELQRVEAEGQ-LQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQ 1851
Query: 1292 QQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKR 1331
+ L+A + +L ++ L+ ++K +EK R
Sbjct: 1852 RALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLR 1891
Score = 37.0 bits (84), Expect = 0.13
Identities = 49/198 (24%), Positives = 94/198 (47%), Gaps = 30/198 (15%)
Query: 1049 KNESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELE-RRFEDEVKRLGWQQQAEL 1107
++E L++E+ S++ A + E + L+ EK+ + RR D+V+R +L
Sbjct: 1837 QDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVER------EKL 1890
Query: 1108 QELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAIT 1167
+ E+ ++L AE RL L + + Q Q++ L +A ++ +E +H+ A
Sbjct: 1891 RSHEDTVRLS--AEKGRLDRTLTGAELEL-AEAQRQIQQL----EAQVVVLEQSHSPA-- 1941
Query: 1168 ILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEE-- 1225
Q + D + Q+L EL++ E+LR + TL + ++ R R R EE
Sbjct: 1942 --QLEVDAQQQQL---------ELQQEVERLRSAQAQTERTLEARERAHRQRVRGLEEQV 1990
Query: 1226 -ALRKNTEEQLEIALAPY 1242
L+ +++L + AP+
Sbjct: 1991 STLKGQLQQELRRSSAPF 2008
Score = 36.6 bits (83), Expect = 0.17
Identities = 48/197 (24%), Positives = 81/197 (41%), Gaps = 22/197 (11%)
Query: 1072 AFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQEL-------EERLQLQFEAEMAR 1124
A A LQ+E + L++ V+ L Q +AE EL ERL+ E
Sbjct: 70 ATEMASLLSLQEENQLLQQELS-RVEDLLAQSRAERDELAIKYNAVSERLEQALRLEPGE 128
Query: 1125 LQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTH 1184
L+ + L+ + + Q+++ AS+ L + ++Q +Q
Sbjct: 129 LETQEPRGLVRQSVELRRQLQEEQASYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCS 188
Query: 1185 ELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNT---------EEQL 1235
ELE++ LE + E + L+D T SQ L R EE +++ EQL
Sbjct: 189 ELEQQLLERSGELEQQRLRD-----TEHSQDLESALIRLEEEQQRSASLAQVNAMLREQL 243
Query: 1236 EIALAPYQHLEEDMKSL 1252
+ A + Q L ED++ +
Sbjct: 244 DQAGSANQALSEDIRKV 260
Score = 33.9 bits (76), Expect = 1.1
Identities = 88/362 (24%), Positives = 144/362 (39%), Gaps = 59/362 (16%)
Query: 1005 RQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEKELSIE- 1063
R+LV +K E+ QLG GEL R S V+E L +
Sbjct: 307 RRLVSEVKMFTERDLLQLG---GELART-------------------SRAVQEAGLGLST 344
Query: 1064 ---LANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKR---LGWQQ-QAELQ--ELEERL 1114
LA R E A EK + +LE + D+V R L QQ Q++L +L R+
Sbjct: 345 GLRLAESRAEAAL-----EKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARV 399
Query: 1115 -QLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDH 1173
+L + Q DQ+ + E +E L AAL E E+ + T L+D
Sbjct: 400 TELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAAL-ETEDGEGLQQT-LRDLA 457
Query: 1174 DHKVQELMSTHELEKKE--LEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNT 1231
+ + S +L E + + LR + + +S R R+ R + +
Sbjct: 458 QAVLSDSESGVQLSGSERTADASNGSLRGLSGQRTPSPPRRSSPGRGRSPRRGPSPACSD 517
Query: 1232 EEQLEI---ALAPYQHLEEDMK----SLKQVLEMKNQQIHEQEKKILELEKLAEKNIILE 1284
L + AL Q +DM+ + + +L +Q+ + E + LE+ ++ L
Sbjct: 518 SSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQR---LR 574
Query: 1285 EKIQVLQQQNEDLKARIDQNTVVTRQLSEENANL-------QEYVEKETQEKKRLSRTNE 1337
+K Q +ED + + + LS E +NL Q+ E+ QE+++L E
Sbjct: 575 DKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQE 634
Query: 1338 EL 1339
EL
Sbjct: 635 EL 636
Score = 33.1 bits (74), Expect = 1.9
Identities = 47/197 (23%), Positives = 87/197 (44%), Gaps = 29/197 (14%)
Query: 1147 LTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKL--RLSLQD 1204
L A+ A+LL ++ + +LQ + +V++L++ E+ EL + + RL
Sbjct: 68 LPATEMASLLSLQEENQ----LLQQELS-RVEDLLAQSRAERDELAIKYNAVSERLEQAL 122
Query: 1205 QVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIA--LAPYQHLEEDMKSLKQVLEMKNQQ 1262
+++ ++Q R R+ E R+ EEQ L YQ ++ L Q L+ K
Sbjct: 123 RLEPGELETQEPRGLVRQSVELRRQLQEEQASYRRKLQAYQEGQQRQAQLVQRLQGK--- 179
Query: 1263 IHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYV 1322
I + +K+ ELE+ +LE ++ QQ+ D + D + + R +
Sbjct: 180 ILQYKKRCSELEQQ-----LLERSGELEQQRLRDTEHSQDLESALIR------------L 222
Query: 1323 EKETQEKKRLSRTNEEL 1339
E+E Q L++ N L
Sbjct: 223 EEEQQRSASLAQVNAML 239
Score = 32.7 bits (73), Expect = 2.5
Identities = 73/336 (21%), Positives = 132/336 (39%), Gaps = 92/336 (27%)
Query: 982 KQRTAAARNGFPPKPDPQAREAE-----RQLVLRLKERCEQQTRQLGVAQGELKRAICGF 1036
++ A+ R + Q R+A+ + +L+ K+RC + +QL GEL++
Sbjct: 149 QEEQASYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQ---- 204
Query: 1037 DALAVATQHFFRKNESALVK---EKELSIELANIR---------------------DEVA 1072
+ + ESAL++ E++ S LA + +V
Sbjct: 205 ---RLRDTEHSQDLESALIRLEEEQQRSASLAQVNAMLREQLDQAGSANQALSEDIRKVT 261
Query: 1073 FHTAKCEK--------LQKEKEELERRFEDEVKR--LGWQQ-------QAELQELEERLQ 1115
+C K ++E+E F +E R L W+Q +E++ ER
Sbjct: 262 NDWTRCRKELEHREAAWRREEESFNAYFSNEHSRLLLLWRQVVGFRRLVSEVKMFTERDL 321
Query: 1116 LQFEAEMA-----------------RLQEEHGDQLLS----IRCQHQEQVED-LTASHDA 1153
LQ E+A RL E + L ++ Q +EQ+ D + D
Sbjct: 322 LQLGGELARTSRAVQEAGLGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDL 381
Query: 1154 ALLEMENNHTVAITILQDDHDHKVQEL-MSTHELEKKELEEN------FEKLR----LSL 1202
A +M+++ A D +V EL ++ LEK+ LE++ EKL L L
Sbjct: 382 AQQQMQSDLDKA------DLSARVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRL 435
Query: 1203 QDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIA 1238
Q+Q T + L+ R +A+ ++E ++++
Sbjct: 436 QEQAALETEDGEGLQQTLRDLAQAVLSDSESGVQLS 471
>gi|82880656 coiled-coil domain containing 46 isoform a [Homo sapiens]
Length = 955
Score = 73.2 bits (178), Expect = 2e-12
Identities = 87/376 (23%), Positives = 168/376 (44%), Gaps = 43/376 (11%)
Query: 1002 EAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEKELS 1061
E Q V +LK++ ++ Q + +L+ F +H + K K +L
Sbjct: 507 EELEQNVCQLKQQLQESELQ---RKQQLRDQENKFQMEKSHLKHIYEK------KAHDLQ 557
Query: 1062 IELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQ-QAELQELEERLQLQFEA 1120
EL +++ K E+ KEKEE R EV+RL QQ A L+E + +++L E
Sbjct: 558 SELDKGKEDTQKKIHKFEEALKEKEEQLTRVT-EVQRLQAQQADAALEEFKRQVELNSEK 616
Query: 1121 EMARLQEE----HGDQLLSIRCQHQE------QVEDLTASHDAALLEMENNHTVAITILQ 1170
A ++E+ D S + ++ Q+ED+ ++ ++E++ H T L
Sbjct: 617 VYAEMKEQMEKVEADLTRSKSLREKQSKEFLWQLEDIRQRYEQQIVELKLEHEQEKTHLL 676
Query: 1171 DDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQ-SQSLRDRARRF----EE 1225
H+ + L+ HE E + LE+ + ++Q+ + +Q + D + EE
Sbjct: 677 QQHNAEKDSLVRDHEREIENLEKQLRAANMEHENQIQEFKKRDAQVIADMEAQVHKLREE 736
Query: 1226 ALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKL--AEKNIIL 1283
+ N++ + ++ EE ++ ++ + N+ E EK +EL+K AE + L
Sbjct: 737 LINVNSQRKQQLVELGLLREEEKQRATREHEIVVNKLKAESEKMKIELKKTHAAETEMTL 796
Query: 1284 EEKIQVLQQQNEDLKARIDQNTVVTRQLS-------EENAN--------LQEYVEKETQE 1328
E+ L+Q ++ ++ +++ + +L EEN+ LQ+ +K E
Sbjct: 797 EKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDE 856
Query: 1329 KKRLSRTNEELLWKLQ 1344
KK+L R N++ + LQ
Sbjct: 857 KKQLIRDNDQAIKVLQ 872
Score = 64.7 bits (156), Expect = 6e-10
Identities = 82/407 (20%), Positives = 178/407 (43%), Gaps = 50/407 (12%)
Query: 949 KDAQKDQDTNKPAVSSPKRVAASTTKLHSPGYPKQRTAAARNGFPPKPDPQAREAERQLV 1008
+D Q ++T + ++ K++ +T+ + + K+ A K D Q + E
Sbjct: 324 RDCQVIRETKEDQIAELKKICEQSTESLNNDWEKKLHNAVAEMEQEKFDLQKQHTEN--- 380
Query: 1009 LRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEKELSIELANIR 1068
++E E +L + E + A +T H KEL + +
Sbjct: 381 --IQELLEDTNVRLNKMESE-------YMAQTQSTNHMI----------KELEARVQQLT 421
Query: 1069 DEVAFHTAKCEKLQKEKEELERRFE------DEVKR----LGWQQQAELQELEER---LQ 1115
E + +KL +EK ELER ++ EVK L ++ + + E+ LQ
Sbjct: 422 GEAENSNLQRQKLIQEKAELERCYQITCSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQ 481
Query: 1116 LQFEAEMARLQEEHG----------DQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVA 1165
+++A++ L++EH ++L CQ ++Q+++ L + EN +
Sbjct: 482 TKYDADINLLKQEHALSASKASSMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQME 541
Query: 1166 ITILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEE 1225
+ L+ ++ K +L S + K++ ++ K +L+++ + LT ++ R +A++ +
Sbjct: 542 KSHLKHIYEKKAHDLQSELDKGKEDTQKKIHKFEEALKEKEEQLTRVTEVQRLQAQQADA 601
Query: 1226 ALRKNTEEQLEI-ALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKIL-ELEKLAEK--NI 1281
AL + + Q+E+ + Y ++E M+ ++ L +Q K+ L +LE + ++
Sbjct: 602 AL-EEFKRQVELNSEKVYAEMKEQMEKVEADLTRSKSLREKQSKEFLWQLEDIRQRYEQQ 660
Query: 1282 ILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQE 1328
I+E K++ Q++ L+ + + R E NL++ + E
Sbjct: 661 IVELKLEHEQEKTHLLQQHNAEKDSLVRDHEREIENLEKQLRAANME 707
Score = 62.4 bits (150), Expect = 3e-09
Identities = 76/324 (23%), Positives = 146/324 (45%), Gaps = 36/324 (11%)
Query: 1037 DALAVATQHFFRKNESALVKEKELSIELANIRDEVAFHTAKC-----EKLQKEKEELERR 1091
+AL + R E ++ ++ L + +V ++ K E+++K + +L R
Sbjct: 576 EALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQVELNSEKVYAEMKEQMEKVEADLTRS 635
Query: 1092 F---EDEVKRLGWQQQAELQELEER---LQLQFEAEMARLQEEHGDQLLSIRCQHQEQVE 1145
E + K WQ + Q E++ L+L+ E E L ++H + S+ H+ ++E
Sbjct: 636 KSLREKQSKEFLWQLEDIRQRYEQQIVELKLEHEQEKTHLLQQHNAEKDSLVRDHEREIE 695
Query: 1146 DLTASHDAALLEMEN------NHTVAITILQDDHDHKV-QELMSTHELEKKELEE----- 1193
+L AA +E EN + + HK+ +EL++ + K++L E
Sbjct: 696 NLEKQLRAANMEHENQIQEFKKRDAQVIADMEAQVHKLREELINVNSQRKQQLVELGLLR 755
Query: 1194 NFEKLRLSLQDQ--VDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEEDMKS 1251
EK R + + + V+ L +S+ ++ ++ A TE LE A + + +E K
Sbjct: 756 EEEKQRATREHEIVVNKLKAESEKMKIELKKTHAA---ETEMTLEKANSKLKQIE---KE 809
Query: 1252 LKQVLEMKNQQIHEQEKKILEL-EKLAEKNIILEEKIQVLQQQNEDLKARI----DQNTV 1306
Q L +Q I E + I L E+ +++ + E ++Q ++Q+ ED K ++ DQ
Sbjct: 810 YTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIK 869
Query: 1307 VTRQLSEENANLQEYVEKETQEKK 1330
V + E +N EK+ Q K+
Sbjct: 870 VLQDELENRSNQVRCAEKKLQHKE 893
Score = 46.6 bits (109), Expect = 2e-04
Identities = 63/318 (19%), Positives = 133/318 (41%), Gaps = 38/318 (11%)
Query: 1055 VKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERL 1114
++EKEL ++ + E FH +EK +L+++ + +V+++ ++ E++EL+
Sbjct: 252 IREKELDMKTKMM--EAKFH--------EEKLKLQQKHDADVQKILERKNNEIEELKTLY 301
Query: 1115 Q-LQFEAEMARLQEEHGDQLLSIRCQ-----HQEQVEDLTASHDAALLEMENN-----HT 1163
+ Q E E + E Q L CQ ++Q+ +L + + + N+ H
Sbjct: 302 RSKQHETEETIRKLEKKVQTLIRDCQVIRETKEDQIAELKKICEQSTESLNNDWEKKLHN 361
Query: 1164 VAITI------LQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLR 1217
+ LQ H +QEL+ + ++E + S + L + Q L
Sbjct: 362 AVAEMEQEKFDLQKQHTENIQELLEDTNVRLNKMESEYMAQTQSTNHMIKELEARVQQLT 421
Query: 1218 DRARRFEEALRKNTEEQLEIALAPYQHLEE--DMKSLKQVLEMKNQQI---HEQEKKILE 1272
A +K +E+ E+ E ++K+ + L + + +EQ K+L+
Sbjct: 422 GEAENSNLQRQKLIQEKAELERCYQITCSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQ 481
Query: 1273 LEKLAEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEEN-----ANLQEYVEKETQ 1327
+ A+ N++ +E + + ++ ++QN +Q +E+ L++ K
Sbjct: 482 TKYDADINLLKQEHALSASKASSMIE-ELEQNVCQLKQQLQESELQRKQQLRDQENKFQM 540
Query: 1328 EKKRLSRTNEELLWKLQT 1345
EK L E+ LQ+
Sbjct: 541 EKSHLKHIYEKKAHDLQS 558
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 72.8 bits (177), Expect = 2e-12
Identities = 83/388 (21%), Positives = 172/388 (44%), Gaps = 44/388 (11%)
Query: 1010 RLKERCEQQTRQLGVAQGELKRAICGFDALA---VATQHFFRKNESALVKEKELSIELAN 1066
++K+ E+ R AQ + + LA + ++ A+ + L E
Sbjct: 2272 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAEL 2331
Query: 1067 IRDEVAFHTAKCEKLQKEKEELERRFEDEVK------RLGWQQQAELQELEERLQLQFEA 1120
++ + + +LQ++KE++ ++ +E + Q+Q E+ ERL+L+ A
Sbjct: 2332 LQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV-A 2390
Query: 1121 EMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHD-HKVQE 1179
EM+R Q + R Q +E E L + A ++ T+ I Q DHD +++E
Sbjct: 2391 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLRE 2450
Query: 1180 LMSTHELEKKELEENFEKLRLSLQD----QVDTLTFQSQSLRD----------RARRFEE 1225
++ E EK++L++ + L+L ++ Q + L ++Q+L+ + RF E
Sbjct: 2451 AIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIE 2510
Query: 1226 ALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIIL-E 1284
+ E+ + +A Q L E+ + +Q +E + Q++ ++ + AE+ + +
Sbjct: 2511 QEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ 2570
Query: 1285 EKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQ 1344
E++Q L+QQ + L+EEN L+E ++ ++ + +EE+
Sbjct: 2571 EELQQLEQQRRQQE----------ELLAEENQRLREQLQLLEEQHRAALAHSEEV----- 2615
Query: 1345 TGDPTSPIKLSPTSPVYRGSSSGPSSPA 1372
S + + T P R + GP++ A
Sbjct: 2616 ---TASQVAATKTLPNGRDALDGPAAEA 2640
Score = 60.1 bits (144), Expect = 1e-08
Identities = 82/346 (23%), Positives = 153/346 (44%), Gaps = 34/346 (9%)
Query: 1000 AREAERQLVL-RLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEK 1058
A +AE +L L R++ E R A+ E R +A + R+ E+ +K
Sbjct: 1939 AGKAELELELGRIRSNAEDTLRSKEQAELEAARQ------RQLAAEEERRRREAEERVQK 1992
Query: 1059 ELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQF 1118
L+ E R A E++++ K ++E E +RL +++AE QE +LQL
Sbjct: 1993 SLAAEEEAARQR----KAALEEVERLKAKVE-----EARRL--RERAE-QESARQLQLAQ 2040
Query: 1119 EAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQ 1178
EA RLQ E +++ Q +++++ + L ++ A ++ + +VQ
Sbjct: 2041 EAAQKRLQAEEKAHAFAVQ-QKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ 2099
Query: 1179 ELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARR--FEEALRKNTEEQ-- 1234
+ + E E+L+ S ++Q Q+Q+ ++ R+ +EA R+ EQ
Sbjct: 2100 --AEREAAQSRRQVEEAERLKQSAEEQAQARA-QAQAAAEKLRKEAEQEAARRAQAEQAA 2156
Query: 1235 LEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQN 1294
L A +E+ K +Q L K Q E L+LE+ + +L+E++Q
Sbjct: 2157 LRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ------ 2210
Query: 1295 EDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELL 1340
LKA + Q+ EE +++ +E+ ++ K R+ N L+
Sbjct: 2211 -RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALI 2255
Score = 58.2 bits (139), Expect = 5e-08
Identities = 108/480 (22%), Positives = 197/480 (41%), Gaps = 81/480 (16%)
Query: 898 EEQPVLKASLPSKDTPKGA-----GRVAPPASSSVTAPRRSLLPAPKSTSTPAGTKKDAQ 952
EE LKAS K GR+ A ++ + ++ L A + A ++ +
Sbjct: 1925 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRR 1984
Query: 953 KDQDTNKPAVSSPKRVAASTTKLHSPGYPKQRTAAARNGFPPKPDPQAREAERQLVLRLK 1012
+ ++ + ++++ + A +QR AA + + +A+ + RL+
Sbjct: 1985 EAEERVQKSLAAEEEAA------------RQRKAALE-------EVERLKAKVEEARRLR 2025
Query: 1013 ERCEQQT-RQLGVAQ-GELKRAICGFDALAVATQHFFRKNESALVKEKELSIELANIRDE 1070
ER EQ++ RQL +AQ KR A A A Q ++ + L +E+ + +L +
Sbjct: 2026 ERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA 2085
Query: 1071 V--AFHTAKCEKLQKEKEELE-RRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQE 1127
A A+ ++Q E+E + RR +E +RL +Q AE ++ + R Q Q AE R +
Sbjct: 2086 ARRAAEEAEEARVQAEREAAQSRRQVEEAERL--KQSAE-EQAQARAQAQAAAEKLRKEA 2142
Query: 1128 EHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELE 1187
E Q + R Q ++ + DA EME + A L+ +
Sbjct: 2143 E---QEAARRAQAEQAALRQKQAADA---EMEKHKKFAEQTLR----------------Q 2180
Query: 1188 KKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEE 1247
K ++E+ LRL L++ + L+ EA R+ ++ + E+ Q E
Sbjct: 2181 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQM--E 2238
Query: 1248 DMKSLKQVLEMKNQQI-------------HEQEKKILELEKLAEKNIILEEKIQVLQQQN 1294
++ LK +E +N+ + E EK E+ A ++ +E ++ Q
Sbjct: 2239 ELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAE 2298
Query: 1295 EDL-----------KARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKL 1343
EDL K ++ TR L E LQ+ E ++ +RL E++ +L
Sbjct: 2299 EDLAQQRALAEKMLKEKMQAVQEATR-LKAEAELLQQQKELAQEQARRLQEDKEQMAQQL 2357
Score = 57.4 bits (137), Expect = 9e-08
Identities = 79/342 (23%), Positives = 145/342 (42%), Gaps = 25/342 (7%)
Query: 999 QAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKE- 1057
QA EAER RL++ ++ RQ+ VA +R+ +A + + F + + L +
Sbjct: 1544 QAEEAER----RLRQAEVERARQVQVALETAQRSA---EAELQSKRASFAEKTAQLERSL 1596
Query: 1058 KELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQ 1117
+E + +A +R+E + + ++ +EE ER E + + LQ E Q
Sbjct: 1597 QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKS 1656
Query: 1118 FEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKV 1177
A Q+E ++ R + +EQ + A E+E +A Q
Sbjct: 1657 LAQAEAEKQKEEAEREARRRGKAEEQA---VRQRELAEQELEKQRQLAEGTAQ------- 1706
Query: 1178 QELMSTHELEKKELE-ENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLE 1236
Q L + EL + E E E+ R L++++ L ++ + + + E L K ++E
Sbjct: 1707 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK-VRAEME 1765
Query: 1237 IALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNED 1296
+ LA EE+ +S E Q++ + + EL + A + L E+ + +Q E+
Sbjct: 1766 VLLASKARAEEESRSTS---EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEE 1822
Query: 1297 LKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEE 1338
AR Q R L+E+ A + E +T+ + L E
Sbjct: 1823 DAAR--QRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1862
Score = 53.9 bits (128), Expect = 1e-06
Identities = 62/294 (21%), Positives = 127/294 (43%), Gaps = 39/294 (13%)
Query: 1051 ESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQEL 1110
E+AL K+++L+ H + ++E +EL++R ++EV R +++A +
Sbjct: 1366 EAALEKQRQLA----------EAHAQAKAQAEREAKELQQRMQEEVVR---REEAAVDAQ 1412
Query: 1111 EERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQ 1170
+++ +Q E + R E Q + + + E+ L + ++ ++ T
Sbjct: 1413 QQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSR-LRIEEEIRVVRLQLEATERQRGGA 1471
Query: 1171 DDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKN 1230
+ ++ E +K++ +E E+LR +QD+ R R+ E L
Sbjct: 1472 EGELQALRARAEEAEAQKRQAQEEAERLRRQVQDE-----------SQRKRQAEVELASR 1520
Query: 1231 TEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKI--LELEKLAEKNIILEEKIQ 1288
+ + E A E ++L Q LE Q E E+++ E+E+ + + LE +
Sbjct: 1521 VKAEAEAA-------REKQRAL-QALEELRLQAEEAERRLRQAEVERARQVQVALETAQR 1572
Query: 1289 VLQQQNEDLKARIDQNTV-VTRQLSEEN---ANLQEYVEKETQEKKRLSRTNEE 1338
+ + + +A + T + R L EE+ A L+E E+ Q++ R EE
Sbjct: 1573 SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREE 1626
Score = 52.8 bits (125), Expect = 2e-06
Identities = 106/512 (20%), Positives = 202/512 (39%), Gaps = 74/512 (14%)
Query: 865 VRSSSVSSVSSTQSGDSAQPEQGRPATRSTFGNEEQPVLKASLPSKDTPKGAGRVAPPAS 924
+R + ++ + + + A+ + R A +S EE LK S A A +
Sbjct: 2079 LRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS---------AEEQAQARA 2129
Query: 925 SSVTAPRRSLLPAPKSTSTPAGTKKDAQKDQDTNKPAVSSPKRVAASTTKLHSPGYPKQR 984
+ A + A + + A ++ A + + + K+ A T L +Q
Sbjct: 2130 QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT--LRQKAQVEQE 2187
Query: 985 TAAARNGFPPKPDPQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQ 1044
R + D Q + +L RLK + RQ + EL + L+
Sbjct: 2188 LTTLRLQLE-ETDHQKNLLDEELQ-RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKA 2245
Query: 1045 HFFRKNESALVKEKELSI----ELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLG 1100
+N + ++++K+ + E A +VA A+ +E L + E+++
Sbjct: 2246 RIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLA--- 2302
Query: 1101 WQQQA--------ELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHD 1152
QQ+A ++Q ++E +L+ EAE+ + Q+E + + +EQ+ A
Sbjct: 2303 -QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2361
Query: 1153 AAL---LEMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTL 1209
LE E + ++ + +V E MS + +E + F K
Sbjct: 2362 QGFQRTLEAERQRQLEMSAEAERLKLRVAE-MSRAQARAEEDAQRFRK------------ 2408
Query: 1210 TFQSQSLRDRARRFEEALRKNTE--EQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQE 1267
Q++ + ++ R E A ++ + LEI H E ++ LE + +++ +QE
Sbjct: 2409 --QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKL-QQE 2465
Query: 1268 KKILEL---------------EKLAEKNIILEEKIQVLQQQN--EDLKARIDQ----NTV 1306
K+L+L E A + L EK +LQ++ E KA+++Q
Sbjct: 2466 AKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVA 2525
Query: 1307 VTRQLSEENANLQEYVEKETQEKKRLSRTNEE 1338
+QL EE Q+ +E QE++RL + EE
Sbjct: 2526 KAQQLREEQQRQQQQME---QERQRLVASMEE 2554
Score = 50.8 bits (120), Expect = 9e-06
Identities = 75/352 (21%), Positives = 149/352 (42%), Gaps = 36/352 (10%)
Query: 1002 EAERQLVLRLKERCEQQTRQLGVAQGELK---RAICGF----DALAVATQHFFRKNESAL 1054
E R+ V +L ER + Q V Q EL+ R + + D L Q R+ E
Sbjct: 1175 ERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQ-- 1232
Query: 1055 VKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERL 1114
++ L+ A +R+++ A E++++ E++E + + + ELQ + +
Sbjct: 1233 IQAMPLADSQA-VREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKA 1291
Query: 1115 QLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHD 1174
QL+ A A+ + I QE V+ T + L + ++ T+ + + +
Sbjct: 1292 QLEPVASPAKKPKVQSGSESVI----QEYVDLRTHYSELTTLTSQYIKFISETLRRMEEE 1347
Query: 1175 HKVQELMSTHELEK-KELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEE 1233
++ E E E+ E+E EK R + + ++ +R +E + + E
Sbjct: 1348 ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEA 1407
Query: 1234 QLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQ 1293
++ A + ++E+++ L+Q E E + K + E + +EE+I+V++ Q
Sbjct: 1408 AVD-AQQQKRSIQEELQQLRQSSEA------EIQAKARQAEAAERSRLRIEEEIRVVRLQ 1460
Query: 1294 NED--------------LKARIDQNTVVTRQLSEENANLQEYVEKETQEKKR 1331
E L+AR ++ RQ EE L+ V+ E+Q K++
Sbjct: 1461 LEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ 1512
Score = 38.5 bits (88), Expect = 0.045
Identities = 35/165 (21%), Positives = 73/165 (44%), Gaps = 7/165 (4%)
Query: 1081 LQKEKEELERRFEDEVKRLGW----QQQAELQELEERLQLQFEAEMARLQEEHGDQLLSI 1136
+++EK +LE+ F+DEV + QQ+ + Q +ER +L E AR ++ ++ +
Sbjct: 2509 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2568
Query: 1137 RCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKV---QELMSTHELEKKELEE 1193
+ + +Q+E + L E + +L++ H + +E+ ++ K L
Sbjct: 2569 KQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPN 2628
Query: 1194 NFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIA 1238
+ L + +F + A+R +EA + EE +A
Sbjct: 2629 GRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLA 2673
Score = 35.0 bits (79), Expect = 0.50
Identities = 82/407 (20%), Positives = 158/407 (38%), Gaps = 78/407 (19%)
Query: 998 PQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKE 1057
P +E R+ R+ E+ + Q G+ +G + + LA+ + +A
Sbjct: 1010 PLDKEPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALP-----EPSPAAPTLR 1064
Query: 1058 KELSIELANIRDEVAFHTAKCEKLQ---------KEKEELERRFEDEVKRLGWQQQAELQ 1108
EL + L + + EKL+ + EE+ R E+++K A L
Sbjct: 1065 SELELTLGKLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKE-AQAVPATLP 1123
Query: 1109 ELEE-RLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAIT 1167
ELE + L+ A Q+ D L QE E L H +E+E
Sbjct: 1124 ELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQ 1183
Query: 1168 ILQDDHDHKVQELMSTHELEKKELEENFEKLRL----------------SLQDQVDTLTF 1211
+L+ + Q +++ ++ ++ELE+ +LR Q+Q+ +
Sbjct: 1184 LLE-----RWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPL 1238
Query: 1212 -QSQSLRDRARRFEEALRKNTEE-------------------------------QLEIAL 1239
SQ++R++ R+ E+AL + E QLE
Sbjct: 1239 ADSQAVREQLRQ-EQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVA 1297
Query: 1240 APYQHLEEDMKSLKQVLEMKNQQIHEQEKKILE---LEKLAEKNIILEEKIQVLQQQNED 1296
+P + + S + E + + H E L ++ ++E +EE+ ++ +QQ +
Sbjct: 1298 SPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAE 1357
Query: 1297 LKARIDQNTVVT---RQLSEENANLQEYVEKETQEKKRLSRTNEELL 1340
+ R+ + RQL+E +A + E+E +E ++ R EE++
Sbjct: 1358 ERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--RMQEEVV 1402
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 72.8 bits (177), Expect = 2e-12
Identities = 83/388 (21%), Positives = 172/388 (44%), Gaps = 44/388 (11%)
Query: 1010 RLKERCEQQTRQLGVAQGELKRAICGFDALA---VATQHFFRKNESALVKEKELSIELAN 1066
++K+ E+ R AQ + + LA + ++ A+ + L E
Sbjct: 2276 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAEL 2335
Query: 1067 IRDEVAFHTAKCEKLQKEKEELERRFEDEVK------RLGWQQQAELQELEERLQLQFEA 1120
++ + + +LQ++KE++ ++ +E + Q+Q E+ ERL+L+ A
Sbjct: 2336 LQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV-A 2394
Query: 1121 EMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHD-HKVQE 1179
EM+R Q + R Q +E E L + A ++ T+ I Q DHD +++E
Sbjct: 2395 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLRE 2454
Query: 1180 LMSTHELEKKELEENFEKLRLSLQD----QVDTLTFQSQSLRD----------RARRFEE 1225
++ E EK++L++ + L+L ++ Q + L ++Q+L+ + RF E
Sbjct: 2455 AIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIE 2514
Query: 1226 ALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIIL-E 1284
+ E+ + +A Q L E+ + +Q +E + Q++ ++ + AE+ + +
Sbjct: 2515 QEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ 2574
Query: 1285 EKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQ 1344
E++Q L+QQ + L+EEN L+E ++ ++ + +EE+
Sbjct: 2575 EELQQLEQQRRQQE----------ELLAEENQRLREQLQLLEEQHRAALAHSEEV----- 2619
Query: 1345 TGDPTSPIKLSPTSPVYRGSSSGPSSPA 1372
S + + T P R + GP++ A
Sbjct: 2620 ---TASQVAATKTLPNGRDALDGPAAEA 2644
Score = 60.1 bits (144), Expect = 1e-08
Identities = 82/346 (23%), Positives = 153/346 (44%), Gaps = 34/346 (9%)
Query: 1000 AREAERQLVL-RLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEK 1058
A +AE +L L R++ E R A+ E R +A + R+ E+ +K
Sbjct: 1943 AGKAELELELGRIRSNAEDTLRSKEQAELEAARQ------RQLAAEEERRRREAEERVQK 1996
Query: 1059 ELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQF 1118
L+ E R A E++++ K ++E E +RL +++AE QE +LQL
Sbjct: 1997 SLAAEEEAARQR----KAALEEVERLKAKVE-----EARRL--RERAE-QESARQLQLAQ 2044
Query: 1119 EAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQ 1178
EA RLQ E +++ Q +++++ + L ++ A ++ + +VQ
Sbjct: 2045 EAAQKRLQAEEKAHAFAVQ-QKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ 2103
Query: 1179 ELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARR--FEEALRKNTEEQ-- 1234
+ + E E+L+ S ++Q Q+Q+ ++ R+ +EA R+ EQ
Sbjct: 2104 --AEREAAQSRRQVEEAERLKQSAEEQAQARA-QAQAAAEKLRKEAEQEAARRAQAEQAA 2160
Query: 1235 LEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQN 1294
L A +E+ K +Q L K Q E L+LE+ + +L+E++Q
Sbjct: 2161 LRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ------ 2214
Query: 1295 EDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELL 1340
LKA + Q+ EE +++ +E+ ++ K R+ N L+
Sbjct: 2215 -RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALI 2259
Score = 58.2 bits (139), Expect = 5e-08
Identities = 108/480 (22%), Positives = 197/480 (41%), Gaps = 81/480 (16%)
Query: 898 EEQPVLKASLPSKDTPKGA-----GRVAPPASSSVTAPRRSLLPAPKSTSTPAGTKKDAQ 952
EE LKAS K GR+ A ++ + ++ L A + A ++ +
Sbjct: 1929 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRR 1988
Query: 953 KDQDTNKPAVSSPKRVAASTTKLHSPGYPKQRTAAARNGFPPKPDPQAREAERQLVLRLK 1012
+ ++ + ++++ + A +QR AA + + +A+ + RL+
Sbjct: 1989 EAEERVQKSLAAEEEAA------------RQRKAALE-------EVERLKAKVEEARRLR 2029
Query: 1013 ERCEQQT-RQLGVAQ-GELKRAICGFDALAVATQHFFRKNESALVKEKELSIELANIRDE 1070
ER EQ++ RQL +AQ KR A A A Q ++ + L +E+ + +L +
Sbjct: 2030 ERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA 2089
Query: 1071 V--AFHTAKCEKLQKEKEELE-RRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQE 1127
A A+ ++Q E+E + RR +E +RL +Q AE ++ + R Q Q AE R +
Sbjct: 2090 ARRAAEEAEEARVQAEREAAQSRRQVEEAERL--KQSAE-EQAQARAQAQAAAEKLRKEA 2146
Query: 1128 EHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELE 1187
E Q + R Q ++ + DA EME + A L+ +
Sbjct: 2147 E---QEAARRAQAEQAALRQKQAADA---EMEKHKKFAEQTLR----------------Q 2184
Query: 1188 KKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEE 1247
K ++E+ LRL L++ + L+ EA R+ ++ + E+ Q E
Sbjct: 2185 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQM--E 2242
Query: 1248 DMKSLKQVLEMKNQQI-------------HEQEKKILELEKLAEKNIILEEKIQVLQQQN 1294
++ LK +E +N+ + E EK E+ A ++ +E ++ Q
Sbjct: 2243 ELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAE 2302
Query: 1295 EDL-----------KARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKL 1343
EDL K ++ TR L E LQ+ E ++ +RL E++ +L
Sbjct: 2303 EDLAQQRALAEKMLKEKMQAVQEATR-LKAEAELLQQQKELAQEQARRLQEDKEQMAQQL 2361
Score = 57.4 bits (137), Expect = 9e-08
Identities = 79/342 (23%), Positives = 145/342 (42%), Gaps = 25/342 (7%)
Query: 999 QAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKE- 1057
QA EAER RL++ ++ RQ+ VA +R+ +A + + F + + L +
Sbjct: 1548 QAEEAER----RLRQAEVERARQVQVALETAQRSA---EAELQSKRASFAEKTAQLERSL 1600
Query: 1058 KELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQ 1117
+E + +A +R+E + + ++ +EE ER E + + LQ E Q
Sbjct: 1601 QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKS 1660
Query: 1118 FEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKV 1177
A Q+E ++ R + +EQ + A E+E +A Q
Sbjct: 1661 LAQAEAEKQKEEAEREARRRGKAEEQA---VRQRELAEQELEKQRQLAEGTAQ------- 1710
Query: 1178 QELMSTHELEKKELE-ENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLE 1236
Q L + EL + E E E+ R L++++ L ++ + + + E L K ++E
Sbjct: 1711 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK-VRAEME 1769
Query: 1237 IALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNED 1296
+ LA EE+ +S E Q++ + + EL + A + L E+ + +Q E+
Sbjct: 1770 VLLASKARAEEESRSTS---EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEE 1826
Query: 1297 LKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEE 1338
AR Q R L+E+ A + E +T+ + L E
Sbjct: 1827 DAAR--QRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1866
Score = 53.9 bits (128), Expect = 1e-06
Identities = 62/294 (21%), Positives = 127/294 (43%), Gaps = 39/294 (13%)
Query: 1051 ESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQEL 1110
E+AL K+++L+ H + ++E +EL++R ++EV R +++A +
Sbjct: 1370 EAALEKQRQLA----------EAHAQAKAQAEREAKELQQRMQEEVVR---REEAAVDAQ 1416
Query: 1111 EERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQ 1170
+++ +Q E + R E Q + + + E+ L + ++ ++ T
Sbjct: 1417 QQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSR-LRIEEEIRVVRLQLEATERQRGGA 1475
Query: 1171 DDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKN 1230
+ ++ E +K++ +E E+LR +QD+ R R+ E L
Sbjct: 1476 EGELQALRARAEEAEAQKRQAQEEAERLRRQVQDE-----------SQRKRQAEVELASR 1524
Query: 1231 TEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKI--LELEKLAEKNIILEEKIQ 1288
+ + E A E ++L Q LE Q E E+++ E+E+ + + LE +
Sbjct: 1525 VKAEAEAA-------REKQRAL-QALEELRLQAEEAERRLRQAEVERARQVQVALETAQR 1576
Query: 1289 VLQQQNEDLKARIDQNTV-VTRQLSEEN---ANLQEYVEKETQEKKRLSRTNEE 1338
+ + + +A + T + R L EE+ A L+E E+ Q++ R EE
Sbjct: 1577 SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREE 1630
Score = 52.8 bits (125), Expect = 2e-06
Identities = 106/512 (20%), Positives = 202/512 (39%), Gaps = 74/512 (14%)
Query: 865 VRSSSVSSVSSTQSGDSAQPEQGRPATRSTFGNEEQPVLKASLPSKDTPKGAGRVAPPAS 924
+R + ++ + + + A+ + R A +S EE LK S A A +
Sbjct: 2083 LRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS---------AEEQAQARA 2133
Query: 925 SSVTAPRRSLLPAPKSTSTPAGTKKDAQKDQDTNKPAVSSPKRVAASTTKLHSPGYPKQR 984
+ A + A + + A ++ A + + + K+ A T L +Q
Sbjct: 2134 QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT--LRQKAQVEQE 2191
Query: 985 TAAARNGFPPKPDPQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQ 1044
R + D Q + +L RLK + RQ + EL + L+
Sbjct: 2192 LTTLRLQLE-ETDHQKNLLDEELQ-RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKA 2249
Query: 1045 HFFRKNESALVKEKELSI----ELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLG 1100
+N + ++++K+ + E A +VA A+ +E L + E+++
Sbjct: 2250 RIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLA--- 2306
Query: 1101 WQQQA--------ELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHD 1152
QQ+A ++Q ++E +L+ EAE+ + Q+E + + +EQ+ A
Sbjct: 2307 -QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2365
Query: 1153 AAL---LEMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTL 1209
LE E + ++ + +V E MS + +E + F K
Sbjct: 2366 QGFQRTLEAERQRQLEMSAEAERLKLRVAE-MSRAQARAEEDAQRFRK------------ 2412
Query: 1210 TFQSQSLRDRARRFEEALRKNTE--EQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQE 1267
Q++ + ++ R E A ++ + LEI H E ++ LE + +++ +QE
Sbjct: 2413 --QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKL-QQE 2469
Query: 1268 KKILEL---------------EKLAEKNIILEEKIQVLQQQN--EDLKARIDQ----NTV 1306
K+L+L E A + L EK +LQ++ E KA+++Q
Sbjct: 2470 AKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVA 2529
Query: 1307 VTRQLSEENANLQEYVEKETQEKKRLSRTNEE 1338
+QL EE Q+ +E QE++RL + EE
Sbjct: 2530 KAQQLREEQQRQQQQME---QERQRLVASMEE 2558
Score = 50.8 bits (120), Expect = 9e-06
Identities = 75/352 (21%), Positives = 149/352 (42%), Gaps = 36/352 (10%)
Query: 1002 EAERQLVLRLKERCEQQTRQLGVAQGELK---RAICGF----DALAVATQHFFRKNESAL 1054
E R+ V +L ER + Q V Q EL+ R + + D L Q R+ E
Sbjct: 1179 ERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQ-- 1236
Query: 1055 VKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERL 1114
++ L+ A +R+++ A E++++ E++E + + + ELQ + +
Sbjct: 1237 IQAMPLADSQA-VREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKA 1295
Query: 1115 QLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHD 1174
QL+ A A+ + I QE V+ T + L + ++ T+ + + +
Sbjct: 1296 QLEPVASPAKKPKVQSGSESVI----QEYVDLRTHYSELTTLTSQYIKFISETLRRMEEE 1351
Query: 1175 HKVQELMSTHELEK-KELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEE 1233
++ E E E+ E+E EK R + + ++ +R +E + + E
Sbjct: 1352 ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEA 1411
Query: 1234 QLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQ 1293
++ A + ++E+++ L+Q E E + K + E + +EE+I+V++ Q
Sbjct: 1412 AVD-AQQQKRSIQEELQQLRQSSEA------EIQAKARQAEAAERSRLRIEEEIRVVRLQ 1464
Query: 1294 NED--------------LKARIDQNTVVTRQLSEENANLQEYVEKETQEKKR 1331
E L+AR ++ RQ EE L+ V+ E+Q K++
Sbjct: 1465 LEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ 1516
Score = 38.5 bits (88), Expect = 0.045
Identities = 35/165 (21%), Positives = 73/165 (44%), Gaps = 7/165 (4%)
Query: 1081 LQKEKEELERRFEDEVKRLGW----QQQAELQELEERLQLQFEAEMARLQEEHGDQLLSI 1136
+++EK +LE+ F+DEV + QQ+ + Q +ER +L E AR ++ ++ +
Sbjct: 2513 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2572
Query: 1137 RCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKV---QELMSTHELEKKELEE 1193
+ + +Q+E + L E + +L++ H + +E+ ++ K L
Sbjct: 2573 KQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPN 2632
Query: 1194 NFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIA 1238
+ L + +F + A+R +EA + EE +A
Sbjct: 2633 GRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLA 2677
Score = 35.0 bits (79), Expect = 0.50
Identities = 82/407 (20%), Positives = 158/407 (38%), Gaps = 78/407 (19%)
Query: 998 PQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKE 1057
P +E R+ R+ E+ + Q G+ +G + + LA+ + +A
Sbjct: 1014 PLDKEPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALP-----EPSPAAPTLR 1068
Query: 1058 KELSIELANIRDEVAFHTAKCEKLQ---------KEKEELERRFEDEVKRLGWQQQAELQ 1108
EL + L + + EKL+ + EE+ R E+++K A L
Sbjct: 1069 SELELTLGKLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKE-AQAVPATLP 1127
Query: 1109 ELEE-RLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAIT 1167
ELE + L+ A Q+ D L QE E L H +E+E
Sbjct: 1128 ELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQ 1187
Query: 1168 ILQDDHDHKVQELMSTHELEKKELEENFEKLRL----------------SLQDQVDTLTF 1211
+L+ + Q +++ ++ ++ELE+ +LR Q+Q+ +
Sbjct: 1188 LLE-----RWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPL 1242
Query: 1212 -QSQSLRDRARRFEEALRKNTEE-------------------------------QLEIAL 1239
SQ++R++ R+ E+AL + E QLE
Sbjct: 1243 ADSQAVREQLRQ-EQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVA 1301
Query: 1240 APYQHLEEDMKSLKQVLEMKNQQIHEQEKKILE---LEKLAEKNIILEEKIQVLQQQNED 1296
+P + + S + E + + H E L ++ ++E +EE+ ++ +QQ +
Sbjct: 1302 SPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAE 1361
Query: 1297 LKARIDQNTVVT---RQLSEENANLQEYVEKETQEKKRLSRTNEELL 1340
+ R+ + RQL+E +A + E+E +E ++ R EE++
Sbjct: 1362 ERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--RMQEEVV 1406
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 72.8 bits (177), Expect = 2e-12
Identities = 83/388 (21%), Positives = 172/388 (44%), Gaps = 44/388 (11%)
Query: 1010 RLKERCEQQTRQLGVAQGELKRAICGFDALA---VATQHFFRKNESALVKEKELSIELAN 1066
++K+ E+ R AQ + + LA + ++ A+ + L E
Sbjct: 2272 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAEL 2331
Query: 1067 IRDEVAFHTAKCEKLQKEKEELERRFEDEVK------RLGWQQQAELQELEERLQLQFEA 1120
++ + + +LQ++KE++ ++ +E + Q+Q E+ ERL+L+ A
Sbjct: 2332 LQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV-A 2390
Query: 1121 EMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHD-HKVQE 1179
EM+R Q + R Q +E E L + A ++ T+ I Q DHD +++E
Sbjct: 2391 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLRE 2450
Query: 1180 LMSTHELEKKELEENFEKLRLSLQD----QVDTLTFQSQSLRD----------RARRFEE 1225
++ E EK++L++ + L+L ++ Q + L ++Q+L+ + RF E
Sbjct: 2451 AIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIE 2510
Query: 1226 ALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIIL-E 1284
+ E+ + +A Q L E+ + +Q +E + Q++ ++ + AE+ + +
Sbjct: 2511 QEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ 2570
Query: 1285 EKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQ 1344
E++Q L+QQ + L+EEN L+E ++ ++ + +EE+
Sbjct: 2571 EELQQLEQQRRQQE----------ELLAEENQRLREQLQLLEEQHRAALAHSEEV----- 2615
Query: 1345 TGDPTSPIKLSPTSPVYRGSSSGPSSPA 1372
S + + T P R + GP++ A
Sbjct: 2616 ---TASQVAATKTLPNGRDALDGPAAEA 2640
Score = 60.1 bits (144), Expect = 1e-08
Identities = 82/346 (23%), Positives = 153/346 (44%), Gaps = 34/346 (9%)
Query: 1000 AREAERQLVL-RLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEK 1058
A +AE +L L R++ E R A+ E R +A + R+ E+ +K
Sbjct: 1939 AGKAELELELGRIRSNAEDTLRSKEQAELEAARQ------RQLAAEEERRRREAEERVQK 1992
Query: 1059 ELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQF 1118
L+ E R A E++++ K ++E E +RL +++AE QE +LQL
Sbjct: 1993 SLAAEEEAARQR----KAALEEVERLKAKVE-----EARRL--RERAE-QESARQLQLAQ 2040
Query: 1119 EAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQ 1178
EA RLQ E +++ Q +++++ + L ++ A ++ + +VQ
Sbjct: 2041 EAAQKRLQAEEKAHAFAVQ-QKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ 2099
Query: 1179 ELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARR--FEEALRKNTEEQ-- 1234
+ + E E+L+ S ++Q Q+Q+ ++ R+ +EA R+ EQ
Sbjct: 2100 --AEREAAQSRRQVEEAERLKQSAEEQAQARA-QAQAAAEKLRKEAEQEAARRAQAEQAA 2156
Query: 1235 LEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQN 1294
L A +E+ K +Q L K Q E L+LE+ + +L+E++Q
Sbjct: 2157 LRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ------ 2210
Query: 1295 EDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELL 1340
LKA + Q+ EE +++ +E+ ++ K R+ N L+
Sbjct: 2211 -RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALI 2255
Score = 58.2 bits (139), Expect = 5e-08
Identities = 108/480 (22%), Positives = 197/480 (41%), Gaps = 81/480 (16%)
Query: 898 EEQPVLKASLPSKDTPKGA-----GRVAPPASSSVTAPRRSLLPAPKSTSTPAGTKKDAQ 952
EE LKAS K GR+ A ++ + ++ L A + A ++ +
Sbjct: 1925 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRR 1984
Query: 953 KDQDTNKPAVSSPKRVAASTTKLHSPGYPKQRTAAARNGFPPKPDPQAREAERQLVLRLK 1012
+ ++ + ++++ + A +QR AA + + +A+ + RL+
Sbjct: 1985 EAEERVQKSLAAEEEAA------------RQRKAALE-------EVERLKAKVEEARRLR 2025
Query: 1013 ERCEQQT-RQLGVAQ-GELKRAICGFDALAVATQHFFRKNESALVKEKELSIELANIRDE 1070
ER EQ++ RQL +AQ KR A A A Q ++ + L +E+ + +L +
Sbjct: 2026 ERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA 2085
Query: 1071 V--AFHTAKCEKLQKEKEELE-RRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQE 1127
A A+ ++Q E+E + RR +E +RL +Q AE ++ + R Q Q AE R +
Sbjct: 2086 ARRAAEEAEEARVQAEREAAQSRRQVEEAERL--KQSAE-EQAQARAQAQAAAEKLRKEA 2142
Query: 1128 EHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELE 1187
E Q + R Q ++ + DA EME + A L+ +
Sbjct: 2143 E---QEAARRAQAEQAALRQKQAADA---EMEKHKKFAEQTLR----------------Q 2180
Query: 1188 KKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEE 1247
K ++E+ LRL L++ + L+ EA R+ ++ + E+ Q E
Sbjct: 2181 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQM--E 2238
Query: 1248 DMKSLKQVLEMKNQQI-------------HEQEKKILELEKLAEKNIILEEKIQVLQQQN 1294
++ LK +E +N+ + E EK E+ A ++ +E ++ Q
Sbjct: 2239 ELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAE 2298
Query: 1295 EDL-----------KARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKL 1343
EDL K ++ TR L E LQ+ E ++ +RL E++ +L
Sbjct: 2299 EDLAQQRALAEKMLKEKMQAVQEATR-LKAEAELLQQQKELAQEQARRLQEDKEQMAQQL 2357
Score = 57.4 bits (137), Expect = 9e-08
Identities = 79/342 (23%), Positives = 145/342 (42%), Gaps = 25/342 (7%)
Query: 999 QAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKE- 1057
QA EAER RL++ ++ RQ+ VA +R+ +A + + F + + L +
Sbjct: 1544 QAEEAER----RLRQAEVERARQVQVALETAQRSA---EAELQSKRASFAEKTAQLERSL 1596
Query: 1058 KELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQ 1117
+E + +A +R+E + + ++ +EE ER E + + LQ E Q
Sbjct: 1597 QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKS 1656
Query: 1118 FEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKV 1177
A Q+E ++ R + +EQ + A E+E +A Q
Sbjct: 1657 LAQAEAEKQKEEAEREARRRGKAEEQA---VRQRELAEQELEKQRQLAEGTAQ------- 1706
Query: 1178 QELMSTHELEKKELE-ENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLE 1236
Q L + EL + E E E+ R L++++ L ++ + + + E L K ++E
Sbjct: 1707 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK-VRAEME 1765
Query: 1237 IALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNED 1296
+ LA EE+ +S E Q++ + + EL + A + L E+ + +Q E+
Sbjct: 1766 VLLASKARAEEESRSTS---EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEE 1822
Query: 1297 LKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEE 1338
AR Q R L+E+ A + E +T+ + L E
Sbjct: 1823 DAAR--QRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1862
Score = 53.9 bits (128), Expect = 1e-06
Identities = 62/294 (21%), Positives = 127/294 (43%), Gaps = 39/294 (13%)
Query: 1051 ESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQEL 1110
E+AL K+++L+ H + ++E +EL++R ++EV R +++A +
Sbjct: 1366 EAALEKQRQLA----------EAHAQAKAQAEREAKELQQRMQEEVVR---REEAAVDAQ 1412
Query: 1111 EERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQ 1170
+++ +Q E + R E Q + + + E+ L + ++ ++ T
Sbjct: 1413 QQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSR-LRIEEEIRVVRLQLEATERQRGGA 1471
Query: 1171 DDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKN 1230
+ ++ E +K++ +E E+LR +QD+ R R+ E L
Sbjct: 1472 EGELQALRARAEEAEAQKRQAQEEAERLRRQVQDE-----------SQRKRQAEVELASR 1520
Query: 1231 TEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKI--LELEKLAEKNIILEEKIQ 1288
+ + E A E ++L Q LE Q E E+++ E+E+ + + LE +
Sbjct: 1521 VKAEAEAA-------REKQRAL-QALEELRLQAEEAERRLRQAEVERARQVQVALETAQR 1572
Query: 1289 VLQQQNEDLKARIDQNTV-VTRQLSEEN---ANLQEYVEKETQEKKRLSRTNEE 1338
+ + + +A + T + R L EE+ A L+E E+ Q++ R EE
Sbjct: 1573 SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREE 1626
Score = 52.8 bits (125), Expect = 2e-06
Identities = 106/512 (20%), Positives = 202/512 (39%), Gaps = 74/512 (14%)
Query: 865 VRSSSVSSVSSTQSGDSAQPEQGRPATRSTFGNEEQPVLKASLPSKDTPKGAGRVAPPAS 924
+R + ++ + + + A+ + R A +S EE LK S A A +
Sbjct: 2079 LRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS---------AEEQAQARA 2129
Query: 925 SSVTAPRRSLLPAPKSTSTPAGTKKDAQKDQDTNKPAVSSPKRVAASTTKLHSPGYPKQR 984
+ A + A + + A ++ A + + + K+ A T L +Q
Sbjct: 2130 QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT--LRQKAQVEQE 2187
Query: 985 TAAARNGFPPKPDPQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQ 1044
R + D Q + +L RLK + RQ + EL + L+
Sbjct: 2188 LTTLRLQLE-ETDHQKNLLDEELQ-RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKA 2245
Query: 1045 HFFRKNESALVKEKELSI----ELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLG 1100
+N + ++++K+ + E A +VA A+ +E L + E+++
Sbjct: 2246 RIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLA--- 2302
Query: 1101 WQQQA--------ELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHD 1152
QQ+A ++Q ++E +L+ EAE+ + Q+E + + +EQ+ A
Sbjct: 2303 -QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2361
Query: 1153 AAL---LEMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTL 1209
LE E + ++ + +V E MS + +E + F K
Sbjct: 2362 QGFQRTLEAERQRQLEMSAEAERLKLRVAE-MSRAQARAEEDAQRFRK------------ 2408
Query: 1210 TFQSQSLRDRARRFEEALRKNTE--EQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQE 1267
Q++ + ++ R E A ++ + LEI H E ++ LE + +++ +QE
Sbjct: 2409 --QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKL-QQE 2465
Query: 1268 KKILEL---------------EKLAEKNIILEEKIQVLQQQN--EDLKARIDQ----NTV 1306
K+L+L E A + L EK +LQ++ E KA+++Q
Sbjct: 2466 AKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVA 2525
Query: 1307 VTRQLSEENANLQEYVEKETQEKKRLSRTNEE 1338
+QL EE Q+ +E QE++RL + EE
Sbjct: 2526 KAQQLREEQQRQQQQME---QERQRLVASMEE 2554
Score = 50.8 bits (120), Expect = 9e-06
Identities = 75/352 (21%), Positives = 149/352 (42%), Gaps = 36/352 (10%)
Query: 1002 EAERQLVLRLKERCEQQTRQLGVAQGELK---RAICGF----DALAVATQHFFRKNESAL 1054
E R+ V +L ER + Q V Q EL+ R + + D L Q R+ E
Sbjct: 1175 ERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQ-- 1232
Query: 1055 VKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERL 1114
++ L+ A +R+++ A E++++ E++E + + + ELQ + +
Sbjct: 1233 IQAMPLADSQA-VREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKA 1291
Query: 1115 QLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHD 1174
QL+ A A+ + I QE V+ T + L + ++ T+ + + +
Sbjct: 1292 QLEPVASPAKKPKVQSGSESVI----QEYVDLRTHYSELTTLTSQYIKFISETLRRMEEE 1347
Query: 1175 HKVQELMSTHELEK-KELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEE 1233
++ E E E+ E+E EK R + + ++ +R +E + + E
Sbjct: 1348 ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEA 1407
Query: 1234 QLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQ 1293
++ A + ++E+++ L+Q E E + K + E + +EE+I+V++ Q
Sbjct: 1408 AVD-AQQQKRSIQEELQQLRQSSEA------EIQAKARQAEAAERSRLRIEEEIRVVRLQ 1460
Query: 1294 NED--------------LKARIDQNTVVTRQLSEENANLQEYVEKETQEKKR 1331
E L+AR ++ RQ EE L+ V+ E+Q K++
Sbjct: 1461 LEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ 1512
Score = 38.5 bits (88), Expect = 0.045
Identities = 35/165 (21%), Positives = 73/165 (44%), Gaps = 7/165 (4%)
Query: 1081 LQKEKEELERRFEDEVKRLGW----QQQAELQELEERLQLQFEAEMARLQEEHGDQLLSI 1136
+++EK +LE+ F+DEV + QQ+ + Q +ER +L E AR ++ ++ +
Sbjct: 2509 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2568
Query: 1137 RCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKV---QELMSTHELEKKELEE 1193
+ + +Q+E + L E + +L++ H + +E+ ++ K L
Sbjct: 2569 KQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPN 2628
Query: 1194 NFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIA 1238
+ L + +F + A+R +EA + EE +A
Sbjct: 2629 GRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLA 2673
Score = 35.0 bits (79), Expect = 0.50
Identities = 82/407 (20%), Positives = 158/407 (38%), Gaps = 78/407 (19%)
Query: 998 PQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKE 1057
P +E R+ R+ E+ + Q G+ +G + + LA+ + +A
Sbjct: 1010 PLDKEPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALP-----EPSPAAPTLR 1064
Query: 1058 KELSIELANIRDEVAFHTAKCEKLQ---------KEKEELERRFEDEVKRLGWQQQAELQ 1108
EL + L + + EKL+ + EE+ R E+++K A L
Sbjct: 1065 SELELTLGKLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKE-AQAVPATLP 1123
Query: 1109 ELEE-RLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAIT 1167
ELE + L+ A Q+ D L QE E L H +E+E
Sbjct: 1124 ELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQ 1183
Query: 1168 ILQDDHDHKVQELMSTHELEKKELEENFEKLRL----------------SLQDQVDTLTF 1211
+L+ + Q +++ ++ ++ELE+ +LR Q+Q+ +
Sbjct: 1184 LLE-----RWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPL 1238
Query: 1212 -QSQSLRDRARRFEEALRKNTEE-------------------------------QLEIAL 1239
SQ++R++ R+ E+AL + E QLE
Sbjct: 1239 ADSQAVREQLRQ-EQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVA 1297
Query: 1240 APYQHLEEDMKSLKQVLEMKNQQIHEQEKKILE---LEKLAEKNIILEEKIQVLQQQNED 1296
+P + + S + E + + H E L ++ ++E +EE+ ++ +QQ +
Sbjct: 1298 SPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAE 1357
Query: 1297 LKARIDQNTVVT---RQLSEENANLQEYVEKETQEKKRLSRTNEELL 1340
+ R+ + RQL+E +A + E+E +E ++ R EE++
Sbjct: 1358 ERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--RMQEEVV 1402
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 72.8 bits (177), Expect = 2e-12
Identities = 83/388 (21%), Positives = 172/388 (44%), Gaps = 44/388 (11%)
Query: 1010 RLKERCEQQTRQLGVAQGELKRAICGFDALA---VATQHFFRKNESALVKEKELSIELAN 1066
++K+ E+ R AQ + + LA + ++ A+ + L E
Sbjct: 2240 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAEL 2299
Query: 1067 IRDEVAFHTAKCEKLQKEKEELERRFEDEVK------RLGWQQQAELQELEERLQLQFEA 1120
++ + + +LQ++KE++ ++ +E + Q+Q E+ ERL+L+ A
Sbjct: 2300 LQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV-A 2358
Query: 1121 EMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHD-HKVQE 1179
EM+R Q + R Q +E E L + A ++ T+ I Q DHD +++E
Sbjct: 2359 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLRE 2418
Query: 1180 LMSTHELEKKELEENFEKLRLSLQD----QVDTLTFQSQSLRD----------RARRFEE 1225
++ E EK++L++ + L+L ++ Q + L ++Q+L+ + RF E
Sbjct: 2419 AIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIE 2478
Query: 1226 ALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIIL-E 1284
+ E+ + +A Q L E+ + +Q +E + Q++ ++ + AE+ + +
Sbjct: 2479 QEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ 2538
Query: 1285 EKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQ 1344
E++Q L+QQ + L+EEN L+E ++ ++ + +EE+
Sbjct: 2539 EELQQLEQQRRQQE----------ELLAEENQRLREQLQLLEEQHRAALAHSEEV----- 2583
Query: 1345 TGDPTSPIKLSPTSPVYRGSSSGPSSPA 1372
S + + T P R + GP++ A
Sbjct: 2584 ---TASQVAATKTLPNGRDALDGPAAEA 2608
Score = 60.1 bits (144), Expect = 1e-08
Identities = 82/346 (23%), Positives = 153/346 (44%), Gaps = 34/346 (9%)
Query: 1000 AREAERQLVL-RLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEK 1058
A +AE +L L R++ E R A+ E R +A + R+ E+ +K
Sbjct: 1907 AGKAELELELGRIRSNAEDTLRSKEQAELEAARQ------RQLAAEEERRRREAEERVQK 1960
Query: 1059 ELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQF 1118
L+ E R A E++++ K ++E E +RL +++AE QE +LQL
Sbjct: 1961 SLAAEEEAARQR----KAALEEVERLKAKVE-----EARRL--RERAE-QESARQLQLAQ 2008
Query: 1119 EAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQ 1178
EA RLQ E +++ Q +++++ + L ++ A ++ + +VQ
Sbjct: 2009 EAAQKRLQAEEKAHAFAVQ-QKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ 2067
Query: 1179 ELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARR--FEEALRKNTEEQ-- 1234
+ + E E+L+ S ++Q Q+Q+ ++ R+ +EA R+ EQ
Sbjct: 2068 --AEREAAQSRRQVEEAERLKQSAEEQAQARA-QAQAAAEKLRKEAEQEAARRAQAEQAA 2124
Query: 1235 LEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQN 1294
L A +E+ K +Q L K Q E L+LE+ + +L+E++Q
Sbjct: 2125 LRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ------ 2178
Query: 1295 EDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELL 1340
LKA + Q+ EE +++ +E+ ++ K R+ N L+
Sbjct: 2179 -RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALI 2223
Score = 58.2 bits (139), Expect = 5e-08
Identities = 108/480 (22%), Positives = 197/480 (41%), Gaps = 81/480 (16%)
Query: 898 EEQPVLKASLPSKDTPKGA-----GRVAPPASSSVTAPRRSLLPAPKSTSTPAGTKKDAQ 952
EE LKAS K GR+ A ++ + ++ L A + A ++ +
Sbjct: 1893 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRR 1952
Query: 953 KDQDTNKPAVSSPKRVAASTTKLHSPGYPKQRTAAARNGFPPKPDPQAREAERQLVLRLK 1012
+ ++ + ++++ + A +QR AA + + +A+ + RL+
Sbjct: 1953 EAEERVQKSLAAEEEAA------------RQRKAALE-------EVERLKAKVEEARRLR 1993
Query: 1013 ERCEQQT-RQLGVAQ-GELKRAICGFDALAVATQHFFRKNESALVKEKELSIELANIRDE 1070
ER EQ++ RQL +AQ KR A A A Q ++ + L +E+ + +L +
Sbjct: 1994 ERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA 2053
Query: 1071 V--AFHTAKCEKLQKEKEELE-RRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQE 1127
A A+ ++Q E+E + RR +E +RL +Q AE ++ + R Q Q AE R +
Sbjct: 2054 ARRAAEEAEEARVQAEREAAQSRRQVEEAERL--KQSAE-EQAQARAQAQAAAEKLRKEA 2110
Query: 1128 EHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELE 1187
E Q + R Q ++ + DA EME + A L+ +
Sbjct: 2111 E---QEAARRAQAEQAALRQKQAADA---EMEKHKKFAEQTLR----------------Q 2148
Query: 1188 KKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEE 1247
K ++E+ LRL L++ + L+ EA R+ ++ + E+ Q E
Sbjct: 2149 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQM--E 2206
Query: 1248 DMKSLKQVLEMKNQQI-------------HEQEKKILELEKLAEKNIILEEKIQVLQQQN 1294
++ LK +E +N+ + E EK E+ A ++ +E ++ Q
Sbjct: 2207 ELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAE 2266
Query: 1295 EDL-----------KARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKL 1343
EDL K ++ TR L E LQ+ E ++ +RL E++ +L
Sbjct: 2267 EDLAQQRALAEKMLKEKMQAVQEATR-LKAEAELLQQQKELAQEQARRLQEDKEQMAQQL 2325
Score = 57.4 bits (137), Expect = 9e-08
Identities = 79/342 (23%), Positives = 145/342 (42%), Gaps = 25/342 (7%)
Query: 999 QAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKE- 1057
QA EAER RL++ ++ RQ+ VA +R+ +A + + F + + L +
Sbjct: 1512 QAEEAER----RLRQAEVERARQVQVALETAQRSA---EAELQSKRASFAEKTAQLERSL 1564
Query: 1058 KELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQ 1117
+E + +A +R+E + + ++ +EE ER E + + LQ E Q
Sbjct: 1565 QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKS 1624
Query: 1118 FEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKV 1177
A Q+E ++ R + +EQ + A E+E +A Q
Sbjct: 1625 LAQAEAEKQKEEAEREARRRGKAEEQA---VRQRELAEQELEKQRQLAEGTAQ------- 1674
Query: 1178 QELMSTHELEKKELE-ENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLE 1236
Q L + EL + E E E+ R L++++ L ++ + + + E L K ++E
Sbjct: 1675 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK-VRAEME 1733
Query: 1237 IALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNED 1296
+ LA EE+ +S E Q++ + + EL + A + L E+ + +Q E+
Sbjct: 1734 VLLASKARAEEESRSTS---EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEE 1790
Query: 1297 LKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEE 1338
AR Q R L+E+ A + E +T+ + L E
Sbjct: 1791 DAAR--QRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1830
Score = 53.9 bits (128), Expect = 1e-06
Identities = 62/294 (21%), Positives = 127/294 (43%), Gaps = 39/294 (13%)
Query: 1051 ESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQEL 1110
E+AL K+++L+ H + ++E +EL++R ++EV R +++A +
Sbjct: 1334 EAALEKQRQLA----------EAHAQAKAQAEREAKELQQRMQEEVVR---REEAAVDAQ 1380
Query: 1111 EERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQ 1170
+++ +Q E + R E Q + + + E+ L + ++ ++ T
Sbjct: 1381 QQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSR-LRIEEEIRVVRLQLEATERQRGGA 1439
Query: 1171 DDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKN 1230
+ ++ E +K++ +E E+LR +QD+ R R+ E L
Sbjct: 1440 EGELQALRARAEEAEAQKRQAQEEAERLRRQVQDE-----------SQRKRQAEVELASR 1488
Query: 1231 TEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKI--LELEKLAEKNIILEEKIQ 1288
+ + E A E ++L Q LE Q E E+++ E+E+ + + LE +
Sbjct: 1489 VKAEAEAA-------REKQRAL-QALEELRLQAEEAERRLRQAEVERARQVQVALETAQR 1540
Query: 1289 VLQQQNEDLKARIDQNTV-VTRQLSEEN---ANLQEYVEKETQEKKRLSRTNEE 1338
+ + + +A + T + R L EE+ A L+E E+ Q++ R EE
Sbjct: 1541 SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREE 1594
Score = 52.8 bits (125), Expect = 2e-06
Identities = 106/512 (20%), Positives = 202/512 (39%), Gaps = 74/512 (14%)
Query: 865 VRSSSVSSVSSTQSGDSAQPEQGRPATRSTFGNEEQPVLKASLPSKDTPKGAGRVAPPAS 924
+R + ++ + + + A+ + R A +S EE LK S A A +
Sbjct: 2047 LRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS---------AEEQAQARA 2097
Query: 925 SSVTAPRRSLLPAPKSTSTPAGTKKDAQKDQDTNKPAVSSPKRVAASTTKLHSPGYPKQR 984
+ A + A + + A ++ A + + + K+ A T L +Q
Sbjct: 2098 QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT--LRQKAQVEQE 2155
Query: 985 TAAARNGFPPKPDPQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQ 1044
R + D Q + +L RLK + RQ + EL + L+
Sbjct: 2156 LTTLRLQLE-ETDHQKNLLDEELQ-RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKA 2213
Query: 1045 HFFRKNESALVKEKELSI----ELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLG 1100
+N + ++++K+ + E A +VA A+ +E L + E+++
Sbjct: 2214 RIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLA--- 2270
Query: 1101 WQQQA--------ELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHD 1152
QQ+A ++Q ++E +L+ EAE+ + Q+E + + +EQ+ A
Sbjct: 2271 -QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2329
Query: 1153 AAL---LEMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTL 1209
LE E + ++ + +V E MS + +E + F K
Sbjct: 2330 QGFQRTLEAERQRQLEMSAEAERLKLRVAE-MSRAQARAEEDAQRFRK------------ 2376
Query: 1210 TFQSQSLRDRARRFEEALRKNTE--EQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQE 1267
Q++ + ++ R E A ++ + LEI H E ++ LE + +++ +QE
Sbjct: 2377 --QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKL-QQE 2433
Query: 1268 KKILEL---------------EKLAEKNIILEEKIQVLQQQN--EDLKARIDQ----NTV 1306
K+L+L E A + L EK +LQ++ E KA+++Q
Sbjct: 2434 AKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVA 2493
Query: 1307 VTRQLSEENANLQEYVEKETQEKKRLSRTNEE 1338
+QL EE Q+ +E QE++RL + EE
Sbjct: 2494 KAQQLREEQQRQQQQME---QERQRLVASMEE 2522
Score = 50.8 bits (120), Expect = 9e-06
Identities = 75/352 (21%), Positives = 149/352 (42%), Gaps = 36/352 (10%)
Query: 1002 EAERQLVLRLKERCEQQTRQLGVAQGELK---RAICGF----DALAVATQHFFRKNESAL 1054
E R+ V +L ER + Q V Q EL+ R + + D L Q R+ E
Sbjct: 1143 ERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQ-- 1200
Query: 1055 VKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERL 1114
++ L+ A +R+++ A E++++ E++E + + + ELQ + +
Sbjct: 1201 IQAMPLADSQA-VREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKA 1259
Query: 1115 QLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHD 1174
QL+ A A+ + I QE V+ T + L + ++ T+ + + +
Sbjct: 1260 QLEPVASPAKKPKVQSGSESVI----QEYVDLRTHYSELTTLTSQYIKFISETLRRMEEE 1315
Query: 1175 HKVQELMSTHELEK-KELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEE 1233
++ E E E+ E+E EK R + + ++ +R +E + + E
Sbjct: 1316 ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEA 1375
Query: 1234 QLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQ 1293
++ A + ++E+++ L+Q E E + K + E + +EE+I+V++ Q
Sbjct: 1376 AVD-AQQQKRSIQEELQQLRQSSEA------EIQAKARQAEAAERSRLRIEEEIRVVRLQ 1428
Query: 1294 NED--------------LKARIDQNTVVTRQLSEENANLQEYVEKETQEKKR 1331
E L+AR ++ RQ EE L+ V+ E+Q K++
Sbjct: 1429 LEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ 1480
Score = 38.5 bits (88), Expect = 0.045
Identities = 35/165 (21%), Positives = 73/165 (44%), Gaps = 7/165 (4%)
Query: 1081 LQKEKEELERRFEDEVKRLGW----QQQAELQELEERLQLQFEAEMARLQEEHGDQLLSI 1136
+++EK +LE+ F+DEV + QQ+ + Q +ER +L E AR ++ ++ +
Sbjct: 2477 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2536
Query: 1137 RCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKV---QELMSTHELEKKELEE 1193
+ + +Q+E + L E + +L++ H + +E+ ++ K L
Sbjct: 2537 KQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPN 2596
Query: 1194 NFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIA 1238
+ L + +F + A+R +EA + EE +A
Sbjct: 2597 GRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLA 2641
Score = 35.0 bits (79), Expect = 0.50
Identities = 82/407 (20%), Positives = 158/407 (38%), Gaps = 78/407 (19%)
Query: 998 PQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKE 1057
P +E R+ R+ E+ + Q G+ +G + + LA+ + +A
Sbjct: 978 PLDKEPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALP-----EPSPAAPTLR 1032
Query: 1058 KELSIELANIRDEVAFHTAKCEKLQ---------KEKEELERRFEDEVKRLGWQQQAELQ 1108
EL + L + + EKL+ + EE+ R E+++K A L
Sbjct: 1033 SELELTLGKLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKE-AQAVPATLP 1091
Query: 1109 ELEE-RLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAIT 1167
ELE + L+ A Q+ D L QE E L H +E+E
Sbjct: 1092 ELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQ 1151
Query: 1168 ILQDDHDHKVQELMSTHELEKKELEENFEKLRL----------------SLQDQVDTLTF 1211
+L+ + Q +++ ++ ++ELE+ +LR Q+Q+ +
Sbjct: 1152 LLE-----RWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPL 1206
Query: 1212 -QSQSLRDRARRFEEALRKNTEE-------------------------------QLEIAL 1239
SQ++R++ R+ E+AL + E QLE
Sbjct: 1207 ADSQAVREQLRQ-EQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVA 1265
Query: 1240 APYQHLEEDMKSLKQVLEMKNQQIHEQEKKILE---LEKLAEKNIILEEKIQVLQQQNED 1296
+P + + S + E + + H E L ++ ++E +EE+ ++ +QQ +
Sbjct: 1266 SPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAE 1325
Query: 1297 LKARIDQNTVVT---RQLSEENANLQEYVEKETQEKKRLSRTNEELL 1340
+ R+ + RQL+E +A + E+E +E ++ R EE++
Sbjct: 1326 ERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--RMQEEVV 1370
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 72.8 bits (177), Expect = 2e-12
Identities = 83/388 (21%), Positives = 172/388 (44%), Gaps = 44/388 (11%)
Query: 1010 RLKERCEQQTRQLGVAQGELKRAICGFDALA---VATQHFFRKNESALVKEKELSIELAN 1066
++K+ E+ R AQ + + LA + ++ A+ + L E
Sbjct: 2409 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAEL 2468
Query: 1067 IRDEVAFHTAKCEKLQKEKEELERRFEDEVK------RLGWQQQAELQELEERLQLQFEA 1120
++ + + +LQ++KE++ ++ +E + Q+Q E+ ERL+L+ A
Sbjct: 2469 LQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV-A 2527
Query: 1121 EMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHD-HKVQE 1179
EM+R Q + R Q +E E L + A ++ T+ I Q DHD +++E
Sbjct: 2528 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLRE 2587
Query: 1180 LMSTHELEKKELEENFEKLRLSLQD----QVDTLTFQSQSLRD----------RARRFEE 1225
++ E EK++L++ + L+L ++ Q + L ++Q+L+ + RF E
Sbjct: 2588 AIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIE 2647
Query: 1226 ALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIIL-E 1284
+ E+ + +A Q L E+ + +Q +E + Q++ ++ + AE+ + +
Sbjct: 2648 QEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ 2707
Query: 1285 EKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQ 1344
E++Q L+QQ + L+EEN L+E ++ ++ + +EE+
Sbjct: 2708 EELQQLEQQRRQQE----------ELLAEENQRLREQLQLLEEQHRAALAHSEEV----- 2752
Query: 1345 TGDPTSPIKLSPTSPVYRGSSSGPSSPA 1372
S + + T P R + GP++ A
Sbjct: 2753 ---TASQVAATKTLPNGRDALDGPAAEA 2777
Score = 60.1 bits (144), Expect = 1e-08
Identities = 82/346 (23%), Positives = 153/346 (44%), Gaps = 34/346 (9%)
Query: 1000 AREAERQLVL-RLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEK 1058
A +AE +L L R++ E R A+ E R +A + R+ E+ +K
Sbjct: 2076 AGKAELELELGRIRSNAEDTLRSKEQAELEAARQ------RQLAAEEERRRREAEERVQK 2129
Query: 1059 ELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQF 1118
L+ E R A E++++ K ++E E +RL +++AE QE +LQL
Sbjct: 2130 SLAAEEEAARQR----KAALEEVERLKAKVE-----EARRL--RERAE-QESARQLQLAQ 2177
Query: 1119 EAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQ 1178
EA RLQ E +++ Q +++++ + L ++ A ++ + +VQ
Sbjct: 2178 EAAQKRLQAEEKAHAFAVQ-QKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ 2236
Query: 1179 ELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARR--FEEALRKNTEEQ-- 1234
+ + E E+L+ S ++Q Q+Q+ ++ R+ +EA R+ EQ
Sbjct: 2237 --AEREAAQSRRQVEEAERLKQSAEEQAQARA-QAQAAAEKLRKEAEQEAARRAQAEQAA 2293
Query: 1235 LEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQN 1294
L A +E+ K +Q L K Q E L+LE+ + +L+E++Q
Sbjct: 2294 LRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ------ 2347
Query: 1295 EDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELL 1340
LKA + Q+ EE +++ +E+ ++ K R+ N L+
Sbjct: 2348 -RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALI 2392
Score = 58.2 bits (139), Expect = 5e-08
Identities = 108/480 (22%), Positives = 197/480 (41%), Gaps = 81/480 (16%)
Query: 898 EEQPVLKASLPSKDTPKGA-----GRVAPPASSSVTAPRRSLLPAPKSTSTPAGTKKDAQ 952
EE LKAS K GR+ A ++ + ++ L A + A ++ +
Sbjct: 2062 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRR 2121
Query: 953 KDQDTNKPAVSSPKRVAASTTKLHSPGYPKQRTAAARNGFPPKPDPQAREAERQLVLRLK 1012
+ ++ + ++++ + A +QR AA + + +A+ + RL+
Sbjct: 2122 EAEERVQKSLAAEEEAA------------RQRKAALE-------EVERLKAKVEEARRLR 2162
Query: 1013 ERCEQQT-RQLGVAQ-GELKRAICGFDALAVATQHFFRKNESALVKEKELSIELANIRDE 1070
ER EQ++ RQL +AQ KR A A A Q ++ + L +E+ + +L +
Sbjct: 2163 ERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA 2222
Query: 1071 V--AFHTAKCEKLQKEKEELE-RRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQE 1127
A A+ ++Q E+E + RR +E +RL +Q AE ++ + R Q Q AE R +
Sbjct: 2223 ARRAAEEAEEARVQAEREAAQSRRQVEEAERL--KQSAE-EQAQARAQAQAAAEKLRKEA 2279
Query: 1128 EHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELE 1187
E Q + R Q ++ + DA EME + A L+ +
Sbjct: 2280 E---QEAARRAQAEQAALRQKQAADA---EMEKHKKFAEQTLR----------------Q 2317
Query: 1188 KKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEE 1247
K ++E+ LRL L++ + L+ EA R+ ++ + E+ Q E
Sbjct: 2318 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQM--E 2375
Query: 1248 DMKSLKQVLEMKNQQI-------------HEQEKKILELEKLAEKNIILEEKIQVLQQQN 1294
++ LK +E +N+ + E EK E+ A ++ +E ++ Q
Sbjct: 2376 ELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAE 2435
Query: 1295 EDL-----------KARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKL 1343
EDL K ++ TR L E LQ+ E ++ +RL E++ +L
Sbjct: 2436 EDLAQQRALAEKMLKEKMQAVQEATR-LKAEAELLQQQKELAQEQARRLQEDKEQMAQQL 2494
Score = 57.4 bits (137), Expect = 9e-08
Identities = 79/342 (23%), Positives = 145/342 (42%), Gaps = 25/342 (7%)
Query: 999 QAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKE- 1057
QA EAER RL++ ++ RQ+ VA +R+ +A + + F + + L +
Sbjct: 1681 QAEEAER----RLRQAEVERARQVQVALETAQRSA---EAELQSKRASFAEKTAQLERSL 1733
Query: 1058 KELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQ 1117
+E + +A +R+E + + ++ +EE ER E + + LQ E Q
Sbjct: 1734 QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKS 1793
Query: 1118 FEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKV 1177
A Q+E ++ R + +EQ + A E+E +A Q
Sbjct: 1794 LAQAEAEKQKEEAEREARRRGKAEEQA---VRQRELAEQELEKQRQLAEGTAQ------- 1843
Query: 1178 QELMSTHELEKKELE-ENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLE 1236
Q L + EL + E E E+ R L++++ L ++ + + + E L K ++E
Sbjct: 1844 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK-VRAEME 1902
Query: 1237 IALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNED 1296
+ LA EE+ +S E Q++ + + EL + A + L E+ + +Q E+
Sbjct: 1903 VLLASKARAEEESRSTS---EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEE 1959
Query: 1297 LKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEE 1338
AR Q R L+E+ A + E +T+ + L E
Sbjct: 1960 DAAR--QRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1999
Score = 53.9 bits (128), Expect = 1e-06
Identities = 62/294 (21%), Positives = 127/294 (43%), Gaps = 39/294 (13%)
Query: 1051 ESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQEL 1110
E+AL K+++L+ H + ++E +EL++R ++EV R +++A +
Sbjct: 1503 EAALEKQRQLA----------EAHAQAKAQAEREAKELQQRMQEEVVR---REEAAVDAQ 1549
Query: 1111 EERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQ 1170
+++ +Q E + R E Q + + + E+ L + ++ ++ T
Sbjct: 1550 QQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSR-LRIEEEIRVVRLQLEATERQRGGA 1608
Query: 1171 DDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKN 1230
+ ++ E +K++ +E E+LR +QD+ R R+ E L
Sbjct: 1609 EGELQALRARAEEAEAQKRQAQEEAERLRRQVQDE-----------SQRKRQAEVELASR 1657
Query: 1231 TEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKI--LELEKLAEKNIILEEKIQ 1288
+ + E A E ++L Q LE Q E E+++ E+E+ + + LE +
Sbjct: 1658 VKAEAEAA-------REKQRAL-QALEELRLQAEEAERRLRQAEVERARQVQVALETAQR 1709
Query: 1289 VLQQQNEDLKARIDQNTV-VTRQLSEEN---ANLQEYVEKETQEKKRLSRTNEE 1338
+ + + +A + T + R L EE+ A L+E E+ Q++ R EE
Sbjct: 1710 SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREE 1763
Score = 52.8 bits (125), Expect = 2e-06
Identities = 106/512 (20%), Positives = 202/512 (39%), Gaps = 74/512 (14%)
Query: 865 VRSSSVSSVSSTQSGDSAQPEQGRPATRSTFGNEEQPVLKASLPSKDTPKGAGRVAPPAS 924
+R + ++ + + + A+ + R A +S EE LK S A A +
Sbjct: 2216 LRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS---------AEEQAQARA 2266
Query: 925 SSVTAPRRSLLPAPKSTSTPAGTKKDAQKDQDTNKPAVSSPKRVAASTTKLHSPGYPKQR 984
+ A + A + + A ++ A + + + K+ A T L +Q
Sbjct: 2267 QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT--LRQKAQVEQE 2324
Query: 985 TAAARNGFPPKPDPQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQ 1044
R + D Q + +L RLK + RQ + EL + L+
Sbjct: 2325 LTTLRLQLE-ETDHQKNLLDEELQ-RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKA 2382
Query: 1045 HFFRKNESALVKEKELSI----ELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLG 1100
+N + ++++K+ + E A +VA A+ +E L + E+++
Sbjct: 2383 RIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLA--- 2439
Query: 1101 WQQQA--------ELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHD 1152
QQ+A ++Q ++E +L+ EAE+ + Q+E + + +EQ+ A
Sbjct: 2440 -QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2498
Query: 1153 AAL---LEMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTL 1209
LE E + ++ + +V E MS + +E + F K
Sbjct: 2499 QGFQRTLEAERQRQLEMSAEAERLKLRVAE-MSRAQARAEEDAQRFRK------------ 2545
Query: 1210 TFQSQSLRDRARRFEEALRKNTE--EQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQE 1267
Q++ + ++ R E A ++ + LEI H E ++ LE + +++ +QE
Sbjct: 2546 --QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKL-QQE 2602
Query: 1268 KKILEL---------------EKLAEKNIILEEKIQVLQQQN--EDLKARIDQ----NTV 1306
K+L+L E A + L EK +LQ++ E KA+++Q
Sbjct: 2603 AKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVA 2662
Query: 1307 VTRQLSEENANLQEYVEKETQEKKRLSRTNEE 1338
+QL EE Q+ +E QE++RL + EE
Sbjct: 2663 KAQQLREEQQRQQQQME---QERQRLVASMEE 2691
Score = 50.8 bits (120), Expect = 9e-06
Identities = 75/352 (21%), Positives = 149/352 (42%), Gaps = 36/352 (10%)
Query: 1002 EAERQLVLRLKERCEQQTRQLGVAQGELK---RAICGF----DALAVATQHFFRKNESAL 1054
E R+ V +L ER + Q V Q EL+ R + + D L Q R+ E
Sbjct: 1312 ERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQ-- 1369
Query: 1055 VKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERL 1114
++ L+ A +R+++ A E++++ E++E + + + ELQ + +
Sbjct: 1370 IQAMPLADSQA-VREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKA 1428
Query: 1115 QLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHD 1174
QL+ A A+ + I QE V+ T + L + ++ T+ + + +
Sbjct: 1429 QLEPVASPAKKPKVQSGSESVI----QEYVDLRTHYSELTTLTSQYIKFISETLRRMEEE 1484
Query: 1175 HKVQELMSTHELEK-KELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEE 1233
++ E E E+ E+E EK R + + ++ +R +E + + E
Sbjct: 1485 ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEA 1544
Query: 1234 QLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQ 1293
++ A + ++E+++ L+Q E E + K + E + +EE+I+V++ Q
Sbjct: 1545 AVD-AQQQKRSIQEELQQLRQSSEA------EIQAKARQAEAAERSRLRIEEEIRVVRLQ 1597
Query: 1294 NED--------------LKARIDQNTVVTRQLSEENANLQEYVEKETQEKKR 1331
E L+AR ++ RQ EE L+ V+ E+Q K++
Sbjct: 1598 LEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ 1649
Score = 38.5 bits (88), Expect = 0.045
Identities = 35/165 (21%), Positives = 73/165 (44%), Gaps = 7/165 (4%)
Query: 1081 LQKEKEELERRFEDEVKRLGW----QQQAELQELEERLQLQFEAEMARLQEEHGDQLLSI 1136
+++EK +LE+ F+DEV + QQ+ + Q +ER +L E AR ++ ++ +
Sbjct: 2646 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2705
Query: 1137 RCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKV---QELMSTHELEKKELEE 1193
+ + +Q+E + L E + +L++ H + +E+ ++ K L
Sbjct: 2706 KQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPN 2765
Query: 1194 NFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIA 1238
+ L + +F + A+R +EA + EE +A
Sbjct: 2766 GRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLA 2810
Score = 35.0 bits (79), Expect = 0.50
Identities = 82/407 (20%), Positives = 158/407 (38%), Gaps = 78/407 (19%)
Query: 998 PQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKE 1057
P +E R+ R+ E+ + Q G+ +G + + LA+ + +A
Sbjct: 1147 PLDKEPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALP-----EPSPAAPTLR 1201
Query: 1058 KELSIELANIRDEVAFHTAKCEKLQ---------KEKEELERRFEDEVKRLGWQQQAELQ 1108
EL + L + + EKL+ + EE+ R E+++K A L
Sbjct: 1202 SELELTLGKLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKE-AQAVPATLP 1260
Query: 1109 ELEE-RLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAIT 1167
ELE + L+ A Q+ D L QE E L H +E+E
Sbjct: 1261 ELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQ 1320
Query: 1168 ILQDDHDHKVQELMSTHELEKKELEENFEKLRL----------------SLQDQVDTLTF 1211
+L+ + Q +++ ++ ++ELE+ +LR Q+Q+ +
Sbjct: 1321 LLE-----RWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPL 1375
Query: 1212 -QSQSLRDRARRFEEALRKNTEE-------------------------------QLEIAL 1239
SQ++R++ R+ E+AL + E QLE
Sbjct: 1376 ADSQAVREQLRQ-EQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVA 1434
Query: 1240 APYQHLEEDMKSLKQVLEMKNQQIHEQEKKILE---LEKLAEKNIILEEKIQVLQQQNED 1296
+P + + S + E + + H E L ++ ++E +EE+ ++ +QQ +
Sbjct: 1435 SPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAE 1494
Query: 1297 LKARIDQNTVVT---RQLSEENANLQEYVEKETQEKKRLSRTNEELL 1340
+ R+ + RQL+E +A + E+E +E ++ R EE++
Sbjct: 1495 ERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--RMQEEVV 1539
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 72.8 bits (177), Expect = 2e-12
Identities = 83/388 (21%), Positives = 172/388 (44%), Gaps = 44/388 (11%)
Query: 1010 RLKERCEQQTRQLGVAQGELKRAICGFDALA---VATQHFFRKNESALVKEKELSIELAN 1066
++K+ E+ R AQ + + LA + ++ A+ + L E
Sbjct: 2250 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAEL 2309
Query: 1067 IRDEVAFHTAKCEKLQKEKEELERRFEDEVK------RLGWQQQAELQELEERLQLQFEA 1120
++ + + +LQ++KE++ ++ +E + Q+Q E+ ERL+L+ A
Sbjct: 2310 LQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV-A 2368
Query: 1121 EMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHD-HKVQE 1179
EM+R Q + R Q +E E L + A ++ T+ I Q DHD +++E
Sbjct: 2369 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLRE 2428
Query: 1180 LMSTHELEKKELEENFEKLRLSLQD----QVDTLTFQSQSLRD----------RARRFEE 1225
++ E EK++L++ + L+L ++ Q + L ++Q+L+ + RF E
Sbjct: 2429 AIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIE 2488
Query: 1226 ALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIIL-E 1284
+ E+ + +A Q L E+ + +Q +E + Q++ ++ + AE+ + +
Sbjct: 2489 QEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ 2548
Query: 1285 EKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQ 1344
E++Q L+QQ + L+EEN L+E ++ ++ + +EE+
Sbjct: 2549 EELQQLEQQRRQQE----------ELLAEENQRLREQLQLLEEQHRAALAHSEEV----- 2593
Query: 1345 TGDPTSPIKLSPTSPVYRGSSSGPSSPA 1372
S + + T P R + GP++ A
Sbjct: 2594 ---TASQVAATKTLPNGRDALDGPAAEA 2618
Score = 60.1 bits (144), Expect = 1e-08
Identities = 82/346 (23%), Positives = 153/346 (44%), Gaps = 34/346 (9%)
Query: 1000 AREAERQLVL-RLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEK 1058
A +AE +L L R++ E R A+ E R +A + R+ E+ +K
Sbjct: 1917 AGKAELELELGRIRSNAEDTLRSKEQAELEAARQ------RQLAAEEERRRREAEERVQK 1970
Query: 1059 ELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQF 1118
L+ E R A E++++ K ++E E +RL +++AE QE +LQL
Sbjct: 1971 SLAAEEEAARQR----KAALEEVERLKAKVE-----EARRL--RERAE-QESARQLQLAQ 2018
Query: 1119 EAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQ 1178
EA RLQ E +++ Q +++++ + L ++ A ++ + +VQ
Sbjct: 2019 EAAQKRLQAEEKAHAFAVQ-QKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ 2077
Query: 1179 ELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARR--FEEALRKNTEEQ-- 1234
+ + E E+L+ S ++Q Q+Q+ ++ R+ +EA R+ EQ
Sbjct: 2078 --AEREAAQSRRQVEEAERLKQSAEEQAQARA-QAQAAAEKLRKEAEQEAARRAQAEQAA 2134
Query: 1235 LEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQN 1294
L A +E+ K +Q L K Q E L+LE+ + +L+E++Q
Sbjct: 2135 LRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ------ 2188
Query: 1295 EDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELL 1340
LKA + Q+ EE +++ +E+ ++ K R+ N L+
Sbjct: 2189 -RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALI 2233
Score = 58.2 bits (139), Expect = 5e-08
Identities = 108/480 (22%), Positives = 197/480 (41%), Gaps = 81/480 (16%)
Query: 898 EEQPVLKASLPSKDTPKGA-----GRVAPPASSSVTAPRRSLLPAPKSTSTPAGTKKDAQ 952
EE LKAS K GR+ A ++ + ++ L A + A ++ +
Sbjct: 1903 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRR 1962
Query: 953 KDQDTNKPAVSSPKRVAASTTKLHSPGYPKQRTAAARNGFPPKPDPQAREAERQLVLRLK 1012
+ ++ + ++++ + A +QR AA + + +A+ + RL+
Sbjct: 1963 EAEERVQKSLAAEEEAA------------RQRKAALE-------EVERLKAKVEEARRLR 2003
Query: 1013 ERCEQQT-RQLGVAQ-GELKRAICGFDALAVATQHFFRKNESALVKEKELSIELANIRDE 1070
ER EQ++ RQL +AQ KR A A A Q ++ + L +E+ + +L +
Sbjct: 2004 ERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA 2063
Query: 1071 V--AFHTAKCEKLQKEKEELE-RRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQE 1127
A A+ ++Q E+E + RR +E +RL +Q AE ++ + R Q Q AE R +
Sbjct: 2064 ARRAAEEAEEARVQAEREAAQSRRQVEEAERL--KQSAE-EQAQARAQAQAAAEKLRKEA 2120
Query: 1128 EHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELE 1187
E Q + R Q ++ + DA EME + A L+ +
Sbjct: 2121 E---QEAARRAQAEQAALRQKQAADA---EMEKHKKFAEQTLR----------------Q 2158
Query: 1188 KKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEE 1247
K ++E+ LRL L++ + L+ EA R+ ++ + E+ Q E
Sbjct: 2159 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQM--E 2216
Query: 1248 DMKSLKQVLEMKNQQI-------------HEQEKKILELEKLAEKNIILEEKIQVLQQQN 1294
++ LK +E +N+ + E EK E+ A ++ +E ++ Q
Sbjct: 2217 ELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAE 2276
Query: 1295 EDL-----------KARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKL 1343
EDL K ++ TR L E LQ+ E ++ +RL E++ +L
Sbjct: 2277 EDLAQQRALAEKMLKEKMQAVQEATR-LKAEAELLQQQKELAQEQARRLQEDKEQMAQQL 2335
Score = 57.4 bits (137), Expect = 9e-08
Identities = 79/342 (23%), Positives = 145/342 (42%), Gaps = 25/342 (7%)
Query: 999 QAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKE- 1057
QA EAER RL++ ++ RQ+ VA +R+ +A + + F + + L +
Sbjct: 1522 QAEEAER----RLRQAEVERARQVQVALETAQRSA---EAELQSKRASFAEKTAQLERSL 1574
Query: 1058 KELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQ 1117
+E + +A +R+E + + ++ +EE ER E + + LQ E Q
Sbjct: 1575 QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKS 1634
Query: 1118 FEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKV 1177
A Q+E ++ R + +EQ + A E+E +A Q
Sbjct: 1635 LAQAEAEKQKEEAEREARRRGKAEEQA---VRQRELAEQELEKQRQLAEGTAQ------- 1684
Query: 1178 QELMSTHELEKKELE-ENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLE 1236
Q L + EL + E E E+ R L++++ L ++ + + + E L K ++E
Sbjct: 1685 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK-VRAEME 1743
Query: 1237 IALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNED 1296
+ LA EE+ +S E Q++ + + EL + A + L E+ + +Q E+
Sbjct: 1744 VLLASKARAEEESRSTS---EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEE 1800
Query: 1297 LKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEE 1338
AR Q R L+E+ A + E +T+ + L E
Sbjct: 1801 DAAR--QRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1840
Score = 53.9 bits (128), Expect = 1e-06
Identities = 62/294 (21%), Positives = 127/294 (43%), Gaps = 39/294 (13%)
Query: 1051 ESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQEL 1110
E+AL K+++L+ H + ++E +EL++R ++EV R +++A +
Sbjct: 1344 EAALEKQRQLA----------EAHAQAKAQAEREAKELQQRMQEEVVR---REEAAVDAQ 1390
Query: 1111 EERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQ 1170
+++ +Q E + R E Q + + + E+ L + ++ ++ T
Sbjct: 1391 QQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSR-LRIEEEIRVVRLQLEATERQRGGA 1449
Query: 1171 DDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKN 1230
+ ++ E +K++ +E E+LR +QD+ R R+ E L
Sbjct: 1450 EGELQALRARAEEAEAQKRQAQEEAERLRRQVQDE-----------SQRKRQAEVELASR 1498
Query: 1231 TEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKI--LELEKLAEKNIILEEKIQ 1288
+ + E A E ++L Q LE Q E E+++ E+E+ + + LE +
Sbjct: 1499 VKAEAEAA-------REKQRAL-QALEELRLQAEEAERRLRQAEVERARQVQVALETAQR 1550
Query: 1289 VLQQQNEDLKARIDQNTV-VTRQLSEEN---ANLQEYVEKETQEKKRLSRTNEE 1338
+ + + +A + T + R L EE+ A L+E E+ Q++ R EE
Sbjct: 1551 SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREE 1604
Score = 52.8 bits (125), Expect = 2e-06
Identities = 106/512 (20%), Positives = 202/512 (39%), Gaps = 74/512 (14%)
Query: 865 VRSSSVSSVSSTQSGDSAQPEQGRPATRSTFGNEEQPVLKASLPSKDTPKGAGRVAPPAS 924
+R + ++ + + + A+ + R A +S EE LK S A A +
Sbjct: 2057 LRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS---------AEEQAQARA 2107
Query: 925 SSVTAPRRSLLPAPKSTSTPAGTKKDAQKDQDTNKPAVSSPKRVAASTTKLHSPGYPKQR 984
+ A + A + + A ++ A + + + K+ A T L +Q
Sbjct: 2108 QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT--LRQKAQVEQE 2165
Query: 985 TAAARNGFPPKPDPQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQ 1044
R + D Q + +L RLK + RQ + EL + L+
Sbjct: 2166 LTTLRLQLE-ETDHQKNLLDEELQ-RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKA 2223
Query: 1045 HFFRKNESALVKEKELSI----ELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLG 1100
+N + ++++K+ + E A +VA A+ +E L + E+++
Sbjct: 2224 RIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLA--- 2280
Query: 1101 WQQQA--------ELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHD 1152
QQ+A ++Q ++E +L+ EAE+ + Q+E + + +EQ+ A
Sbjct: 2281 -QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2339
Query: 1153 AAL---LEMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTL 1209
LE E + ++ + +V E MS + +E + F K
Sbjct: 2340 QGFQRTLEAERQRQLEMSAEAERLKLRVAE-MSRAQARAEEDAQRFRK------------ 2386
Query: 1210 TFQSQSLRDRARRFEEALRKNTE--EQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQE 1267
Q++ + ++ R E A ++ + LEI H E ++ LE + +++ +QE
Sbjct: 2387 --QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKL-QQE 2443
Query: 1268 KKILEL---------------EKLAEKNIILEEKIQVLQQQN--EDLKARIDQ----NTV 1306
K+L+L E A + L EK +LQ++ E KA+++Q
Sbjct: 2444 AKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVA 2503
Query: 1307 VTRQLSEENANLQEYVEKETQEKKRLSRTNEE 1338
+QL EE Q+ +E QE++RL + EE
Sbjct: 2504 KAQQLREEQQRQQQQME---QERQRLVASMEE 2532
Score = 50.8 bits (120), Expect = 9e-06
Identities = 75/352 (21%), Positives = 149/352 (42%), Gaps = 36/352 (10%)
Query: 1002 EAERQLVLRLKERCEQQTRQLGVAQGELK---RAICGF----DALAVATQHFFRKNESAL 1054
E R+ V +L ER + Q V Q EL+ R + + D L Q R+ E
Sbjct: 1153 ERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQ-- 1210
Query: 1055 VKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERL 1114
++ L+ A +R+++ A E++++ E++E + + + ELQ + +
Sbjct: 1211 IQAMPLADSQA-VREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKA 1269
Query: 1115 QLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHD 1174
QL+ A A+ + I QE V+ T + L + ++ T+ + + +
Sbjct: 1270 QLEPVASPAKKPKVQSGSESVI----QEYVDLRTHYSELTTLTSQYIKFISETLRRMEEE 1325
Query: 1175 HKVQELMSTHELEK-KELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEE 1233
++ E E E+ E+E EK R + + ++ +R +E + + E
Sbjct: 1326 ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEA 1385
Query: 1234 QLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQ 1293
++ A + ++E+++ L+Q E E + K + E + +EE+I+V++ Q
Sbjct: 1386 AVD-AQQQKRSIQEELQQLRQSSEA------EIQAKARQAEAAERSRLRIEEEIRVVRLQ 1438
Query: 1294 NED--------------LKARIDQNTVVTRQLSEENANLQEYVEKETQEKKR 1331
E L+AR ++ RQ EE L+ V+ E+Q K++
Sbjct: 1439 LEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ 1490
Score = 38.5 bits (88), Expect = 0.045
Identities = 35/165 (21%), Positives = 73/165 (44%), Gaps = 7/165 (4%)
Query: 1081 LQKEKEELERRFEDEVKRLGW----QQQAELQELEERLQLQFEAEMARLQEEHGDQLLSI 1136
+++EK +LE+ F+DEV + QQ+ + Q +ER +L E AR ++ ++ +
Sbjct: 2487 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2546
Query: 1137 RCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKV---QELMSTHELEKKELEE 1193
+ + +Q+E + L E + +L++ H + +E+ ++ K L
Sbjct: 2547 KQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPN 2606
Query: 1194 NFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIA 1238
+ L + +F + A+R +EA + EE +A
Sbjct: 2607 GRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLA 2651
Score = 35.0 bits (79), Expect = 0.50
Identities = 82/407 (20%), Positives = 158/407 (38%), Gaps = 78/407 (19%)
Query: 998 PQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKE 1057
P +E R+ R+ E+ + Q G+ +G + + LA+ + +A
Sbjct: 988 PLDKEPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALP-----EPSPAAPTLR 1042
Query: 1058 KELSIELANIRDEVAFHTAKCEKLQ---------KEKEELERRFEDEVKRLGWQQQAELQ 1108
EL + L + + EKL+ + EE+ R E+++K A L
Sbjct: 1043 SELELTLGKLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKE-AQAVPATLP 1101
Query: 1109 ELEE-RLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAIT 1167
ELE + L+ A Q+ D L QE E L H +E+E
Sbjct: 1102 ELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQ 1161
Query: 1168 ILQDDHDHKVQELMSTHELEKKELEENFEKLRL----------------SLQDQVDTLTF 1211
+L+ + Q +++ ++ ++ELE+ +LR Q+Q+ +
Sbjct: 1162 LLE-----RWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPL 1216
Query: 1212 -QSQSLRDRARRFEEALRKNTEE-------------------------------QLEIAL 1239
SQ++R++ R+ E+AL + E QLE
Sbjct: 1217 ADSQAVREQLRQ-EQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVA 1275
Query: 1240 APYQHLEEDMKSLKQVLEMKNQQIHEQEKKILE---LEKLAEKNIILEEKIQVLQQQNED 1296
+P + + S + E + + H E L ++ ++E +EE+ ++ +QQ +
Sbjct: 1276 SPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAE 1335
Query: 1297 LKARIDQNTVVT---RQLSEENANLQEYVEKETQEKKRLSRTNEELL 1340
+ R+ + RQL+E +A + E+E +E ++ R EE++
Sbjct: 1336 ERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--RMQEEVV 1380
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 72.8 bits (177), Expect = 2e-12
Identities = 83/388 (21%), Positives = 172/388 (44%), Gaps = 44/388 (11%)
Query: 1010 RLKERCEQQTRQLGVAQGELKRAICGFDALA---VATQHFFRKNESALVKEKELSIELAN 1066
++K+ E+ R AQ + + LA + ++ A+ + L E
Sbjct: 2258 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAEL 2317
Query: 1067 IRDEVAFHTAKCEKLQKEKEELERRFEDEVK------RLGWQQQAELQELEERLQLQFEA 1120
++ + + +LQ++KE++ ++ +E + Q+Q E+ ERL+L+ A
Sbjct: 2318 LQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV-A 2376
Query: 1121 EMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHD-HKVQE 1179
EM+R Q + R Q +E E L + A ++ T+ I Q DHD +++E
Sbjct: 2377 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLRE 2436
Query: 1180 LMSTHELEKKELEENFEKLRLSLQD----QVDTLTFQSQSLRD----------RARRFEE 1225
++ E EK++L++ + L+L ++ Q + L ++Q+L+ + RF E
Sbjct: 2437 AIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIE 2496
Query: 1226 ALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIIL-E 1284
+ E+ + +A Q L E+ + +Q +E + Q++ ++ + AE+ + +
Sbjct: 2497 QEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ 2556
Query: 1285 EKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQ 1344
E++Q L+QQ + L+EEN L+E ++ ++ + +EE+
Sbjct: 2557 EELQQLEQQRRQQE----------ELLAEENQRLREQLQLLEEQHRAALAHSEEV----- 2601
Query: 1345 TGDPTSPIKLSPTSPVYRGSSSGPSSPA 1372
S + + T P R + GP++ A
Sbjct: 2602 ---TASQVAATKTLPNGRDALDGPAAEA 2626
Score = 60.1 bits (144), Expect = 1e-08
Identities = 82/346 (23%), Positives = 153/346 (44%), Gaps = 34/346 (9%)
Query: 1000 AREAERQLVL-RLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEK 1058
A +AE +L L R++ E R A+ E R +A + R+ E+ +K
Sbjct: 1925 AGKAELELELGRIRSNAEDTLRSKEQAELEAARQ------RQLAAEEERRRREAEERVQK 1978
Query: 1059 ELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQF 1118
L+ E R A E++++ K ++E E +RL +++AE QE +LQL
Sbjct: 1979 SLAAEEEAARQR----KAALEEVERLKAKVE-----EARRL--RERAE-QESARQLQLAQ 2026
Query: 1119 EAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQ 1178
EA RLQ E +++ Q +++++ + L ++ A ++ + +VQ
Sbjct: 2027 EAAQKRLQAEEKAHAFAVQ-QKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ 2085
Query: 1179 ELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARR--FEEALRKNTEEQ-- 1234
+ + E E+L+ S ++Q Q+Q+ ++ R+ +EA R+ EQ
Sbjct: 2086 --AEREAAQSRRQVEEAERLKQSAEEQAQARA-QAQAAAEKLRKEAEQEAARRAQAEQAA 2142
Query: 1235 LEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQN 1294
L A +E+ K +Q L K Q E L+LE+ + +L+E++Q
Sbjct: 2143 LRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ------ 2196
Query: 1295 EDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELL 1340
LKA + Q+ EE +++ +E+ ++ K R+ N L+
Sbjct: 2197 -RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALI 2241
Score = 58.2 bits (139), Expect = 5e-08
Identities = 108/480 (22%), Positives = 197/480 (41%), Gaps = 81/480 (16%)
Query: 898 EEQPVLKASLPSKDTPKGA-----GRVAPPASSSVTAPRRSLLPAPKSTSTPAGTKKDAQ 952
EE LKAS K GR+ A ++ + ++ L A + A ++ +
Sbjct: 1911 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRR 1970
Query: 953 KDQDTNKPAVSSPKRVAASTTKLHSPGYPKQRTAAARNGFPPKPDPQAREAERQLVLRLK 1012
+ ++ + ++++ + A +QR AA + + +A+ + RL+
Sbjct: 1971 EAEERVQKSLAAEEEAA------------RQRKAALE-------EVERLKAKVEEARRLR 2011
Query: 1013 ERCEQQT-RQLGVAQ-GELKRAICGFDALAVATQHFFRKNESALVKEKELSIELANIRDE 1070
ER EQ++ RQL +AQ KR A A A Q ++ + L +E+ + +L +
Sbjct: 2012 ERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA 2071
Query: 1071 V--AFHTAKCEKLQKEKEELE-RRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQE 1127
A A+ ++Q E+E + RR +E +RL +Q AE ++ + R Q Q AE R +
Sbjct: 2072 ARRAAEEAEEARVQAEREAAQSRRQVEEAERL--KQSAE-EQAQARAQAQAAAEKLRKEA 2128
Query: 1128 EHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELE 1187
E Q + R Q ++ + DA EME + A L+ +
Sbjct: 2129 E---QEAARRAQAEQAALRQKQAADA---EMEKHKKFAEQTLR----------------Q 2166
Query: 1188 KKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEE 1247
K ++E+ LRL L++ + L+ EA R+ ++ + E+ Q E
Sbjct: 2167 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQM--E 2224
Query: 1248 DMKSLKQVLEMKNQQI-------------HEQEKKILELEKLAEKNIILEEKIQVLQQQN 1294
++ LK +E +N+ + E EK E+ A ++ +E ++ Q
Sbjct: 2225 ELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAE 2284
Query: 1295 EDL-----------KARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKL 1343
EDL K ++ TR L E LQ+ E ++ +RL E++ +L
Sbjct: 2285 EDLAQQRALAEKMLKEKMQAVQEATR-LKAEAELLQQQKELAQEQARRLQEDKEQMAQQL 2343
Score = 57.4 bits (137), Expect = 9e-08
Identities = 79/342 (23%), Positives = 145/342 (42%), Gaps = 25/342 (7%)
Query: 999 QAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKE- 1057
QA EAER RL++ ++ RQ+ VA +R+ +A + + F + + L +
Sbjct: 1530 QAEEAER----RLRQAEVERARQVQVALETAQRSA---EAELQSKRASFAEKTAQLERSL 1582
Query: 1058 KELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQ 1117
+E + +A +R+E + + ++ +EE ER E + + LQ E Q
Sbjct: 1583 QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKS 1642
Query: 1118 FEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKV 1177
A Q+E ++ R + +EQ + A E+E +A Q
Sbjct: 1643 LAQAEAEKQKEEAEREARRRGKAEEQA---VRQRELAEQELEKQRQLAEGTAQ------- 1692
Query: 1178 QELMSTHELEKKELE-ENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLE 1236
Q L + EL + E E E+ R L++++ L ++ + + + E L K ++E
Sbjct: 1693 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK-VRAEME 1751
Query: 1237 IALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNED 1296
+ LA EE+ +S E Q++ + + EL + A + L E+ + +Q E+
Sbjct: 1752 VLLASKARAEEESRSTS---EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEE 1808
Query: 1297 LKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEE 1338
AR Q R L+E+ A + E +T+ + L E
Sbjct: 1809 DAAR--QRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1848
Score = 53.9 bits (128), Expect = 1e-06
Identities = 62/294 (21%), Positives = 127/294 (43%), Gaps = 39/294 (13%)
Query: 1051 ESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQEL 1110
E+AL K+++L+ H + ++E +EL++R ++EV R +++A +
Sbjct: 1352 EAALEKQRQLA----------EAHAQAKAQAEREAKELQQRMQEEVVR---REEAAVDAQ 1398
Query: 1111 EERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQ 1170
+++ +Q E + R E Q + + + E+ L + ++ ++ T
Sbjct: 1399 QQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSR-LRIEEEIRVVRLQLEATERQRGGA 1457
Query: 1171 DDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKN 1230
+ ++ E +K++ +E E+LR +QD+ R R+ E L
Sbjct: 1458 EGELQALRARAEEAEAQKRQAQEEAERLRRQVQDE-----------SQRKRQAEVELASR 1506
Query: 1231 TEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKI--LELEKLAEKNIILEEKIQ 1288
+ + E A E ++L Q LE Q E E+++ E+E+ + + LE +
Sbjct: 1507 VKAEAEAA-------REKQRAL-QALEELRLQAEEAERRLRQAEVERARQVQVALETAQR 1558
Query: 1289 VLQQQNEDLKARIDQNTV-VTRQLSEEN---ANLQEYVEKETQEKKRLSRTNEE 1338
+ + + +A + T + R L EE+ A L+E E+ Q++ R EE
Sbjct: 1559 SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREE 1612
Score = 52.8 bits (125), Expect = 2e-06
Identities = 106/512 (20%), Positives = 202/512 (39%), Gaps = 74/512 (14%)
Query: 865 VRSSSVSSVSSTQSGDSAQPEQGRPATRSTFGNEEQPVLKASLPSKDTPKGAGRVAPPAS 924
+R + ++ + + + A+ + R A +S EE LK S A A +
Sbjct: 2065 LRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS---------AEEQAQARA 2115
Query: 925 SSVTAPRRSLLPAPKSTSTPAGTKKDAQKDQDTNKPAVSSPKRVAASTTKLHSPGYPKQR 984
+ A + A + + A ++ A + + + K+ A T L +Q
Sbjct: 2116 QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT--LRQKAQVEQE 2173
Query: 985 TAAARNGFPPKPDPQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQ 1044
R + D Q + +L RLK + RQ + EL + L+
Sbjct: 2174 LTTLRLQLE-ETDHQKNLLDEELQ-RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKA 2231
Query: 1045 HFFRKNESALVKEKELSI----ELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLG 1100
+N + ++++K+ + E A +VA A+ +E L + E+++
Sbjct: 2232 RIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLA--- 2288
Query: 1101 WQQQA--------ELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHD 1152
QQ+A ++Q ++E +L+ EAE+ + Q+E + + +EQ+ A
Sbjct: 2289 -QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2347
Query: 1153 AAL---LEMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTL 1209
LE E + ++ + +V E MS + +E + F K
Sbjct: 2348 QGFQRTLEAERQRQLEMSAEAERLKLRVAE-MSRAQARAEEDAQRFRK------------ 2394
Query: 1210 TFQSQSLRDRARRFEEALRKNTE--EQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQE 1267
Q++ + ++ R E A ++ + LEI H E ++ LE + +++ +QE
Sbjct: 2395 --QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKL-QQE 2451
Query: 1268 KKILEL---------------EKLAEKNIILEEKIQVLQQQN--EDLKARIDQ----NTV 1306
K+L+L E A + L EK +LQ++ E KA+++Q
Sbjct: 2452 AKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVA 2511
Query: 1307 VTRQLSEENANLQEYVEKETQEKKRLSRTNEE 1338
+QL EE Q+ +E QE++RL + EE
Sbjct: 2512 KAQQLREEQQRQQQQME---QERQRLVASMEE 2540
Score = 50.8 bits (120), Expect = 9e-06
Identities = 75/352 (21%), Positives = 149/352 (42%), Gaps = 36/352 (10%)
Query: 1002 EAERQLVLRLKERCEQQTRQLGVAQGELK---RAICGF----DALAVATQHFFRKNESAL 1054
E R+ V +L ER + Q V Q EL+ R + + D L Q R+ E
Sbjct: 1161 ERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQ-- 1218
Query: 1055 VKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERL 1114
++ L+ A +R+++ A E++++ E++E + + + ELQ + +
Sbjct: 1219 IQAMPLADSQA-VREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKA 1277
Query: 1115 QLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHD 1174
QL+ A A+ + I QE V+ T + L + ++ T+ + + +
Sbjct: 1278 QLEPVASPAKKPKVQSGSESVI----QEYVDLRTHYSELTTLTSQYIKFISETLRRMEEE 1333
Query: 1175 HKVQELMSTHELEK-KELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEE 1233
++ E E E+ E+E EK R + + ++ +R +E + + E
Sbjct: 1334 ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEA 1393
Query: 1234 QLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQ 1293
++ A + ++E+++ L+Q E E + K + E + +EE+I+V++ Q
Sbjct: 1394 AVD-AQQQKRSIQEELQQLRQSSEA------EIQAKARQAEAAERSRLRIEEEIRVVRLQ 1446
Query: 1294 NED--------------LKARIDQNTVVTRQLSEENANLQEYVEKETQEKKR 1331
E L+AR ++ RQ EE L+ V+ E+Q K++
Sbjct: 1447 LEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ 1498
Score = 38.5 bits (88), Expect = 0.045
Identities = 35/165 (21%), Positives = 73/165 (44%), Gaps = 7/165 (4%)
Query: 1081 LQKEKEELERRFEDEVKRLGW----QQQAELQELEERLQLQFEAEMARLQEEHGDQLLSI 1136
+++EK +LE+ F+DEV + QQ+ + Q +ER +L E AR ++ ++ +
Sbjct: 2495 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2554
Query: 1137 RCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKV---QELMSTHELEKKELEE 1193
+ + +Q+E + L E + +L++ H + +E+ ++ K L
Sbjct: 2555 KQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPN 2614
Query: 1194 NFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIA 1238
+ L + +F + A+R +EA + EE +A
Sbjct: 2615 GRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLA 2659
Score = 35.0 bits (79), Expect = 0.50
Identities = 82/407 (20%), Positives = 158/407 (38%), Gaps = 78/407 (19%)
Query: 998 PQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKE 1057
P +E R+ R+ E+ + Q G+ +G + + LA+ + +A
Sbjct: 996 PLDKEPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALP-----EPSPAAPTLR 1050
Query: 1058 KELSIELANIRDEVAFHTAKCEKLQ---------KEKEELERRFEDEVKRLGWQQQAELQ 1108
EL + L + + EKL+ + EE+ R E+++K A L
Sbjct: 1051 SELELTLGKLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKE-AQAVPATLP 1109
Query: 1109 ELEE-RLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAIT 1167
ELE + L+ A Q+ D L QE E L H +E+E
Sbjct: 1110 ELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQ 1169
Query: 1168 ILQDDHDHKVQELMSTHELEKKELEENFEKLRL----------------SLQDQVDTLTF 1211
+L+ + Q +++ ++ ++ELE+ +LR Q+Q+ +
Sbjct: 1170 LLE-----RWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPL 1224
Query: 1212 -QSQSLRDRARRFEEALRKNTEE-------------------------------QLEIAL 1239
SQ++R++ R+ E+AL + E QLE
Sbjct: 1225 ADSQAVREQLRQ-EQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVA 1283
Query: 1240 APYQHLEEDMKSLKQVLEMKNQQIHEQEKKILE---LEKLAEKNIILEEKIQVLQQQNED 1296
+P + + S + E + + H E L ++ ++E +EE+ ++ +QQ +
Sbjct: 1284 SPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAE 1343
Query: 1297 LKARIDQNTVVT---RQLSEENANLQEYVEKETQEKKRLSRTNEELL 1340
+ R+ + RQL+E +A + E+E +E ++ R EE++
Sbjct: 1344 ERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--RMQEEVV 1388
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 72.8 bits (177), Expect = 2e-12
Identities = 83/388 (21%), Positives = 172/388 (44%), Gaps = 44/388 (11%)
Query: 1010 RLKERCEQQTRQLGVAQGELKRAICGFDALA---VATQHFFRKNESALVKEKELSIELAN 1066
++K+ E+ R AQ + + LA + ++ A+ + L E
Sbjct: 2299 KMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAEL 2358
Query: 1067 IRDEVAFHTAKCEKLQKEKEELERRFEDEVK------RLGWQQQAELQELEERLQLQFEA 1120
++ + + +LQ++KE++ ++ +E + Q+Q E+ ERL+L+ A
Sbjct: 2359 LQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV-A 2417
Query: 1121 EMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHD-HKVQE 1179
EM+R Q + R Q +E E L + A ++ T+ I Q DHD +++E
Sbjct: 2418 EMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLRE 2477
Query: 1180 LMSTHELEKKELEENFEKLRLSLQD----QVDTLTFQSQSLRD----------RARRFEE 1225
++ E EK++L++ + L+L ++ Q + L ++Q+L+ + RF E
Sbjct: 2478 AIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIE 2537
Query: 1226 ALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIIL-E 1284
+ E+ + +A Q L E+ + +Q +E + Q++ ++ + AE+ + +
Sbjct: 2538 QEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQ 2597
Query: 1285 EKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQ 1344
E++Q L+QQ + L+EEN L+E ++ ++ + +EE+
Sbjct: 2598 EELQQLEQQRRQQE----------ELLAEENQRLREQLQLLEEQHRAALAHSEEV----- 2642
Query: 1345 TGDPTSPIKLSPTSPVYRGSSSGPSSPA 1372
S + + T P R + GP++ A
Sbjct: 2643 ---TASQVAATKTLPNGRDALDGPAAEA 2667
Score = 60.1 bits (144), Expect = 1e-08
Identities = 82/346 (23%), Positives = 153/346 (44%), Gaps = 34/346 (9%)
Query: 1000 AREAERQLVL-RLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEK 1058
A +AE +L L R++ E R A+ E R +A + R+ E+ +K
Sbjct: 1966 AGKAELELELGRIRSNAEDTLRSKEQAELEAARQ------RQLAAEEERRRREAEERVQK 2019
Query: 1059 ELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQF 1118
L+ E R A E++++ K ++E E +RL +++AE QE +LQL
Sbjct: 2020 SLAAEEEAARQR----KAALEEVERLKAKVE-----EARRL--RERAE-QESARQLQLAQ 2067
Query: 1119 EAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQ 1178
EA RLQ E +++ Q +++++ + L ++ A ++ + +VQ
Sbjct: 2068 EAAQKRLQAEEKAHAFAVQ-QKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ 2126
Query: 1179 ELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARR--FEEALRKNTEEQ-- 1234
+ + E E+L+ S ++Q Q+Q+ ++ R+ +EA R+ EQ
Sbjct: 2127 --AEREAAQSRRQVEEAERLKQSAEEQAQARA-QAQAAAEKLRKEAEQEAARRAQAEQAA 2183
Query: 1235 LEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQN 1294
L A +E+ K +Q L K Q E L+LE+ + +L+E++Q
Sbjct: 2184 LRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ------ 2237
Query: 1295 EDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELL 1340
LKA + Q+ EE +++ +E+ ++ K R+ N L+
Sbjct: 2238 -RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALI 2282
Score = 58.2 bits (139), Expect = 5e-08
Identities = 108/480 (22%), Positives = 197/480 (41%), Gaps = 81/480 (16%)
Query: 898 EEQPVLKASLPSKDTPKGA-----GRVAPPASSSVTAPRRSLLPAPKSTSTPAGTKKDAQ 952
EE LKAS K GR+ A ++ + ++ L A + A ++ +
Sbjct: 1952 EEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRR 2011
Query: 953 KDQDTNKPAVSSPKRVAASTTKLHSPGYPKQRTAAARNGFPPKPDPQAREAERQLVLRLK 1012
+ ++ + ++++ + A +QR AA + + +A+ + RL+
Sbjct: 2012 EAEERVQKSLAAEEEAA------------RQRKAALE-------EVERLKAKVEEARRLR 2052
Query: 1013 ERCEQQT-RQLGVAQ-GELKRAICGFDALAVATQHFFRKNESALVKEKELSIELANIRDE 1070
ER EQ++ RQL +AQ KR A A A Q ++ + L +E+ + +L +
Sbjct: 2053 ERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEA 2112
Query: 1071 V--AFHTAKCEKLQKEKEELE-RRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQE 1127
A A+ ++Q E+E + RR +E +RL +Q AE ++ + R Q Q AE R +
Sbjct: 2113 ARRAAEEAEEARVQAEREAAQSRRQVEEAERL--KQSAE-EQAQARAQAQAAAEKLRKEA 2169
Query: 1128 EHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELE 1187
E Q + R Q ++ + DA EME + A L+ +
Sbjct: 2170 E---QEAARRAQAEQAALRQKQAADA---EMEKHKKFAEQTLR----------------Q 2207
Query: 1188 KKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEE 1247
K ++E+ LRL L++ + L+ EA R+ ++ + E+ Q E
Sbjct: 2208 KAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQM--E 2265
Query: 1248 DMKSLKQVLEMKNQQI-------------HEQEKKILELEKLAEKNIILEEKIQVLQQQN 1294
++ LK +E +N+ + E EK E+ A ++ +E ++ Q
Sbjct: 2266 ELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAE 2325
Query: 1295 EDL-----------KARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKL 1343
EDL K ++ TR L E LQ+ E ++ +RL E++ +L
Sbjct: 2326 EDLAQQRALAEKMLKEKMQAVQEATR-LKAEAELLQQQKELAQEQARRLQEDKEQMAQQL 2384
Score = 57.4 bits (137), Expect = 9e-08
Identities = 79/342 (23%), Positives = 145/342 (42%), Gaps = 25/342 (7%)
Query: 999 QAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKE- 1057
QA EAER RL++ ++ RQ+ VA +R+ +A + + F + + L +
Sbjct: 1571 QAEEAER----RLRQAEVERARQVQVALETAQRSA---EAELQSKRASFAEKTAQLERSL 1623
Query: 1058 KELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQ 1117
+E + +A +R+E + + ++ +EE ER E + + LQ E Q
Sbjct: 1624 QEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKS 1683
Query: 1118 FEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKV 1177
A Q+E ++ R + +EQ + A E+E +A Q
Sbjct: 1684 LAQAEAEKQKEEAEREARRRGKAEEQA---VRQRELAEQELEKQRQLAEGTAQ------- 1733
Query: 1178 QELMSTHELEKKELE-ENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLE 1236
Q L + EL + E E E+ R L++++ L ++ + + + E L K ++E
Sbjct: 1734 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAK-VRAEME 1792
Query: 1237 IALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNED 1296
+ LA EE+ +S E Q++ + + EL + A + L E+ + +Q E+
Sbjct: 1793 VLLASKARAEEESRSTS---EKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEE 1849
Query: 1297 LKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEE 1338
AR Q R L+E+ A + E +T+ + L E
Sbjct: 1850 DAAR--QRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAE 1889
Score = 53.9 bits (128), Expect = 1e-06
Identities = 62/294 (21%), Positives = 127/294 (43%), Gaps = 39/294 (13%)
Query: 1051 ESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQEL 1110
E+AL K+++L+ H + ++E +EL++R ++EV R +++A +
Sbjct: 1393 EAALEKQRQLA----------EAHAQAKAQAEREAKELQQRMQEEVVR---REEAAVDAQ 1439
Query: 1111 EERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQ 1170
+++ +Q E + R E Q + + + E+ L + ++ ++ T
Sbjct: 1440 QQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSR-LRIEEEIRVVRLQLEATERQRGGA 1498
Query: 1171 DDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKN 1230
+ ++ E +K++ +E E+LR +QD+ R R+ E L
Sbjct: 1499 EGELQALRARAEEAEAQKRQAQEEAERLRRQVQDE-----------SQRKRQAEVELASR 1547
Query: 1231 TEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKI--LELEKLAEKNIILEEKIQ 1288
+ + E A E ++L Q LE Q E E+++ E+E+ + + LE +
Sbjct: 1548 VKAEAEAA-------REKQRAL-QALEELRLQAEEAERRLRQAEVERARQVQVALETAQR 1599
Query: 1289 VLQQQNEDLKARIDQNTV-VTRQLSEEN---ANLQEYVEKETQEKKRLSRTNEE 1338
+ + + +A + T + R L EE+ A L+E E+ Q++ R EE
Sbjct: 1600 SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREE 1653
Score = 52.8 bits (125), Expect = 2e-06
Identities = 106/512 (20%), Positives = 202/512 (39%), Gaps = 74/512 (14%)
Query: 865 VRSSSVSSVSSTQSGDSAQPEQGRPATRSTFGNEEQPVLKASLPSKDTPKGAGRVAPPAS 924
+R + ++ + + + A+ + R A +S EE LK S A A +
Sbjct: 2106 LRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQS---------AEEQAQARA 2156
Query: 925 SSVTAPRRSLLPAPKSTSTPAGTKKDAQKDQDTNKPAVSSPKRVAASTTKLHSPGYPKQR 984
+ A + A + + A ++ A + + + K+ A T L +Q
Sbjct: 2157 QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQT--LRQKAQVEQE 2214
Query: 985 TAAARNGFPPKPDPQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQ 1044
R + D Q + +L RLK + RQ + EL + L+
Sbjct: 2215 LTTLRLQLE-ETDHQKNLLDEELQ-RLKAEATEAARQRSQVEEELFSVRVQMEELSKLKA 2272
Query: 1045 HFFRKNESALVKEKELSI----ELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLG 1100
+N + ++++K+ + E A +VA A+ +E L + E+++
Sbjct: 2273 RIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLA--- 2329
Query: 1101 WQQQA--------ELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHD 1152
QQ+A ++Q ++E +L+ EAE+ + Q+E + + +EQ+ A
Sbjct: 2330 -QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2388
Query: 1153 AAL---LEMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTL 1209
LE E + ++ + +V E MS + +E + F K
Sbjct: 2389 QGFQRTLEAERQRQLEMSAEAERLKLRVAE-MSRAQARAEEDAQRFRK------------ 2435
Query: 1210 TFQSQSLRDRARRFEEALRKNTE--EQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQE 1267
Q++ + ++ R E A ++ + LEI H E ++ LE + +++ +QE
Sbjct: 2436 --QAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKL-QQE 2492
Query: 1268 KKILEL---------------EKLAEKNIILEEKIQVLQQQN--EDLKARIDQ----NTV 1306
K+L+L E A + L EK +LQ++ E KA+++Q
Sbjct: 2493 AKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVA 2552
Query: 1307 VTRQLSEENANLQEYVEKETQEKKRLSRTNEE 1338
+QL EE Q+ +E QE++RL + EE
Sbjct: 2553 KAQQLREEQQRQQQQME---QERQRLVASMEE 2581
Score = 50.8 bits (120), Expect = 9e-06
Identities = 75/352 (21%), Positives = 149/352 (42%), Gaps = 36/352 (10%)
Query: 1002 EAERQLVLRLKERCEQQTRQLGVAQGELK---RAICGF----DALAVATQHFFRKNESAL 1054
E R+ V +L ER + Q V Q EL+ R + + D L Q R+ E
Sbjct: 1202 ERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQ-- 1259
Query: 1055 VKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERL 1114
++ L+ A +R+++ A E++++ E++E + + + ELQ + +
Sbjct: 1260 IQAMPLADSQA-VREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKA 1318
Query: 1115 QLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHD 1174
QL+ A A+ + I QE V+ T + L + ++ T+ + + +
Sbjct: 1319 QLEPVASPAKKPKVQSGSESVI----QEYVDLRTHYSELTTLTSQYIKFISETLRRMEEE 1374
Query: 1175 HKVQELMSTHELEK-KELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEE 1233
++ E E E+ E+E EK R + + ++ +R +E + + E
Sbjct: 1375 ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEA 1434
Query: 1234 QLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQ 1293
++ A + ++E+++ L+Q E E + K + E + +EE+I+V++ Q
Sbjct: 1435 AVD-AQQQKRSIQEELQQLRQSSEA------EIQAKARQAEAAERSRLRIEEEIRVVRLQ 1487
Query: 1294 NED--------------LKARIDQNTVVTRQLSEENANLQEYVEKETQEKKR 1331
E L+AR ++ RQ EE L+ V+ E+Q K++
Sbjct: 1488 LEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ 1539
Score = 38.5 bits (88), Expect = 0.045
Identities = 35/165 (21%), Positives = 73/165 (44%), Gaps = 7/165 (4%)
Query: 1081 LQKEKEELERRFEDEVKRLGW----QQQAELQELEERLQLQFEAEMARLQEEHGDQLLSI 1136
+++EK +LE+ F+DEV + QQ+ + Q +ER +L E AR ++ ++ +
Sbjct: 2536 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2595
Query: 1137 RCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKV---QELMSTHELEKKELEE 1193
+ + +Q+E + L E + +L++ H + +E+ ++ K L
Sbjct: 2596 KQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPN 2655
Query: 1194 NFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIA 1238
+ L + +F + A+R +EA + EE +A
Sbjct: 2656 GRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLA 2700
Score = 35.0 bits (79), Expect = 0.50
Identities = 82/407 (20%), Positives = 158/407 (38%), Gaps = 78/407 (19%)
Query: 998 PQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKE 1057
P +E R+ R+ E+ + Q G+ +G + + LA+ + +A
Sbjct: 1037 PLDKEPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALP-----EPSPAAPTLR 1091
Query: 1058 KELSIELANIRDEVAFHTAKCEKLQ---------KEKEELERRFEDEVKRLGWQQQAELQ 1108
EL + L + + EKL+ + EE+ R E+++K A L
Sbjct: 1092 SELELTLGKLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKE-AQAVPATLP 1150
Query: 1109 ELEE-RLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAIT 1167
ELE + L+ A Q+ D L QE E L H +E+E
Sbjct: 1151 ELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQ 1210
Query: 1168 ILQDDHDHKVQELMSTHELEKKELEENFEKLRL----------------SLQDQVDTLTF 1211
+L+ + Q +++ ++ ++ELE+ +LR Q+Q+ +
Sbjct: 1211 LLE-----RWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPL 1265
Query: 1212 -QSQSLRDRARRFEEALRKNTEE-------------------------------QLEIAL 1239
SQ++R++ R+ E+AL + E QLE
Sbjct: 1266 ADSQAVREQLRQ-EQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVA 1324
Query: 1240 APYQHLEEDMKSLKQVLEMKNQQIHEQEKKILE---LEKLAEKNIILEEKIQVLQQQNED 1296
+P + + S + E + + H E L ++ ++E +EE+ ++ +QQ +
Sbjct: 1325 SPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAE 1384
Query: 1297 LKARIDQNTVVT---RQLSEENANLQEYVEKETQEKKRLSRTNEELL 1340
+ R+ + RQL+E +A + E+E +E ++ R EE++
Sbjct: 1385 ERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ--RMQEEVV 1429
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 72.0 bits (175), Expect = 4e-12
Identities = 96/448 (21%), Positives = 184/448 (41%), Gaps = 59/448 (13%)
Query: 905 ASLPSKDTPKGAGRVAPPASSSVTAPRRSLLPAPKSTSTPAGTKKDAQKDQDTNKPAVSS 964
A S +TP + + T + S LP +++ AG + +SS
Sbjct: 101 ADTTSPETPDSSASKVLKREGTDTTAKTSKLPTRPASTGVAGASSSLGPSGSASAGELSS 160
Query: 965 PKRVAASTTKLHSPGYPKQRTAAARNGFPPKPDP-QAREAERQLVLRLKERCEQQTRQLG 1023
+ + T L +P P + PP P P + E R V L+E+ E
Sbjct: 161 SEPSTPAQTPLAAPIIPTP-VLTSPGAVPPLPSPSKEEEGLRAQVRDLEEKLE------- 212
Query: 1024 VAQGELKRAICGFDALAVATQHFFRKNESALVKEKEL-SIELANIRDEVAFHTAKCEKLQ 1082
T R + A +KE E I+L +++ + K+Q
Sbjct: 213 -------------------TLRLKRAEDKAKLKELEKHKIQLEQVQEWKS-------KMQ 246
Query: 1083 KEKEELERRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQE 1142
+++ +L+RR ++ K +A+ + +EE EMA L +E ++ Q+
Sbjct: 247 EQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAE---SLQQ 303
Query: 1143 QVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQE-LMSTHELEKKELEENFEKLRLS 1201
+VE AL E + T + IL+ + + K + S+++L K+LEE +L+ +
Sbjct: 304 EVE--------ALKERVDELTTDLEILKAEIEEKGSDGAASSYQL--KQLEEQNARLKDA 353
Query: 1202 LQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQ 1261
L D S S + + ++ + K +E LE+ + L+E++ + ++ +
Sbjct: 354 LVRMRDL----SSSEKQEHVKLQKLMEKKNQE-LEVVRQQRERLQEELSQAESTIDELKE 408
Query: 1262 QIHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEY 1321
Q+ +E L ++N+ LEEK++ L++ DL+A + N + E L+E
Sbjct: 409 QVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELREQ 468
Query: 1322 VE----KETQEKKRLSRTNEELLWKLQT 1345
++ + + +KR+ E + QT
Sbjct: 469 LDMAGARVREAQKRVEAAQETVADYQQT 496
Score = 50.4 bits (119), Expect = 1e-05
Identities = 43/185 (23%), Positives = 90/185 (48%), Gaps = 11/185 (5%)
Query: 1176 KVQELMSTHELEKKELE-ENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQ 1234
+ ++ ELEK +++ E ++ + +Q+Q L + + R A+ EA + EE
Sbjct: 218 RAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEM 277
Query: 1235 ------LEIALAPYQHLEEDMKSLKQVLEMKNQQIHE--QEKKIL--ELEKLAEKNIILE 1284
+E+A + EE +SL+Q +E +++ E + +IL E+E+
Sbjct: 278 ADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASS 337
Query: 1285 EKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQ 1344
+++ L++QN LK + + ++ +E+ LQ+ +EK+ QE + + + E L +L
Sbjct: 338 YQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELS 397
Query: 1345 TGDPT 1349
+ T
Sbjct: 398 QAEST 402
Score = 33.9 bits (76), Expect = 1.1
Identities = 29/136 (21%), Positives = 62/136 (45%), Gaps = 5/136 (3%)
Query: 1240 APYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDLKA 1299
A + LEE +++L+ ++ E EK ++LE++ E ++E+ LQ++ ++ +
Sbjct: 202 AQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARK 261
Query: 1300 RIDQNTVVTRQLSEENANLQEYVE-----KETQEKKRLSRTNEELLWKLQTGDPTSPIKL 1354
+ + EE A+ + +E KE E++ S E K + + T+ +++
Sbjct: 262 EAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEI 321
Query: 1355 SPTSPVYRGSSSGPSS 1370
+GS SS
Sbjct: 322 LKAEIEEKGSDGAASS 337
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 71.6 bits (174), Expect = 5e-12
Identities = 87/346 (25%), Positives = 158/346 (45%), Gaps = 52/346 (15%)
Query: 1049 KNESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRF----EDEVKRLGWQ-- 1102
K E E +EL + EV + K E L+KEK + R E E++RL Q
Sbjct: 572 KAEIVSASESRKELELKH-EAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLL 630
Query: 1103 --QQAELQELEERLQLQFEAEMARLQEEHG----DQLLSIRCQHQEQVEDLTASHDAALL 1156
+ EL +L+E L+++ + +L++ G Q+ ++ + +++E + D L+
Sbjct: 631 FSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDN-LI 689
Query: 1157 EMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKLRL------SLQDQVDTLT 1210
+N + I+ L+D V L+ EL++ E LR +L+ +V L
Sbjct: 690 TKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQ 749
Query: 1211 FQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKI 1270
+++ L + + E L++ QLE A L+++ K+L+ +L++ E+
Sbjct: 750 LKTELLEKQMKEKENDLQEKFA-QLE---AENSILKDEKKTLEDMLKIHTPVSQEERLIF 805
Query: 1271 LELEKLAEKNIILEEKIQVLQQQNEDLKAR-IDQNTVVTRQ-----LSEEN--ANLQEYV 1322
L+ K K+ + E++I++L ++NEDLK + I N + +Q +E+N N QE
Sbjct: 806 LDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQ 865
Query: 1323 E------------------KETQEKKRLSRTNEELLWKLQTGDPTS 1350
E +E + K +L NEEL LQ +PT+
Sbjct: 866 EEYACLLKVKDDLEDSKNKQELEYKSKLKALNEEL--HLQRINPTT 909
Score = 66.6 bits (161), Expect = 2e-10
Identities = 75/310 (24%), Positives = 146/310 (47%), Gaps = 33/310 (10%)
Query: 1055 VKEKE-LSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEER 1113
+KE E +E+ + DEV QK+ EL+ E E +LG ++ + +ELE+
Sbjct: 3186 LKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELED- 3244
Query: 1114 LQLQFEAEMAR-----LQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITI 1168
L+ E++ R L E QLL+ + Q+++E +DA L E E + + +
Sbjct: 3245 LKFSLESQKQRNLQLNLLLEQQKQLLN---ESQQKIESQRMLYDAQLSE-EQGRNLELQV 3300
Query: 1169 LQDDHDHKVQELMSTHELEKK-----ELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRF 1223
L + +++E+ ST + E++ + + + R L + D L + L ++ R
Sbjct: 3301 LLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSE-DLLKELQKQLEEKHSRI 3359
Query: 1224 EEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIIL 1283
E L + + +L+ +L Q +E+D + ++ L+ + + E +KK+ E L
Sbjct: 3360 VELLNETEKYKLD-SLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHE----------L 3408
Query: 1284 EEKIQVLQQQNEDLKARIDQNTVVTRQLS--EENANLQEYVEKETQEKKRL--SRTNEEL 1339
+ K++ LQ+Q E+ + ++ + + ++L + QE +E +E +R+ NE
Sbjct: 3409 QSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQNLNEPT 3468
Query: 1340 LWKLQTGDPT 1349
W L T D T
Sbjct: 3469 TWSL-TSDRT 3477
Score = 63.2 bits (152), Expect = 2e-09
Identities = 90/396 (22%), Positives = 168/396 (42%), Gaps = 53/396 (13%)
Query: 999 QAREAERQLVLR--LKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVK 1056
Q +EA L + L+ER +++R EL +A D A F R+ +
Sbjct: 1885 QKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDI 1944
Query: 1057 EKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELE----E 1112
L EL + + A+ +++Q+E+E L R+ E G +Q LQE E E
Sbjct: 1945 IDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKE 2004
Query: 1113 RLQLQFEAEMAR-----------------------LQEEHGDQLLSIRCQHQ---EQVED 1146
+L++Q +AE R L++E +L+ +R Q+Q +Q+E
Sbjct: 2005 KLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEK 2064
Query: 1147 LTASHDAALLEMENNHTVAITILQ--DDHDHKVQELMSTHELEKKELEENFEKLRLSLQD 1204
+ D ++ E+ V +Q + V E + +E+E+ L+
Sbjct: 2065 MRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDK 2124
Query: 1205 QVDTLTFQSQSLRDRARRFEEALR-----KNTEEQLEIALAPYQHLEEDMK--------- 1250
+ L + Q RD R EE + + E+ L ++ +Q +E+
Sbjct: 2125 CSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQKVEDRKHFGAVEAKPE 2184
Query: 1251 -SLKQVLEMKNQQIHEQEKKILELEKLAEK-NIILEEKIQVLQQQNEDLKARIDQNTVVT 1308
SL+ L+ + I +EK+I LE+ E+ LE K + +QQ + L+ + ++T
Sbjct: 2185 LSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRL 2244
Query: 1309 RQLSEENANLQEYVEK---ETQEKKRLSRTNEELLW 1341
++L +EN ++ +EK +E +S ++ +L+
Sbjct: 2245 QELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLF 2280
Score = 58.5 bits (140), Expect = 4e-08
Identities = 74/319 (23%), Positives = 150/319 (47%), Gaps = 39/319 (12%)
Query: 1028 ELKRAICGFDALAVATQH-FFRKNESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKE 1086
ELK + D L Q +KN+ K + +EL N + + + + ++L E
Sbjct: 347 ELKDKLTTADKLLGELQEQIVQKNQEI----KNMKLELTNSKQKERQSSEEIKQLMGTVE 402
Query: 1087 ELERR------FE-DEVKRLGWQQQAELQELEERLQLQFEAEMARLQEE----HGDQLLS 1135
EL++R FE D V+R+ + Q +L++L L + ++ ++++E H Q+
Sbjct: 403 ELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEE 462
Query: 1136 IRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENF 1195
++ +H+ ++E+ S+ + + + + I ++ + K+Q+ S E K+EL
Sbjct: 463 MKTRHKGEMENALRSYSNITVNEDQIKLMNVAI--NELNIKLQDTNSQKEKLKEELGLIL 520
Query: 1196 EKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEEDMKSLKQV 1255
E+ + +LQ Q++ L + R++ +R + + + + L E KSL V
Sbjct: 521 EE-KCALQRQLEDLVEELSFSREQIQRARQTIAEQESK-----------LNEAHKSLSTV 568
Query: 1256 LEMKNQQIHEQE-KKILELEKLAE-------KNIILEEKIQVLQQQNEDLKARIDQ-NTV 1306
++K + + E +K LEL+ AE ++ +EK VL + E +A +++ T
Sbjct: 569 EDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQ 628
Query: 1307 VTRQLSEENANLQEYVEKE 1325
+ EE + L+E +E E
Sbjct: 629 LLFSHEEELSKLKEDLEIE 647
Score = 57.8 bits (138), Expect = 7e-08
Identities = 64/276 (23%), Positives = 123/276 (44%), Gaps = 33/276 (11%)
Query: 1063 ELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQFEAEM 1122
E+ + + + T KC +L KE+L+R ++ + E+++LE R++
Sbjct: 2110 EVEQLANHLKEKTDKCSELLLSKEQLQRDIQE--------RNEEIEKLEFRVR------- 2154
Query: 1123 ARLQEEHGDQLLSIRCQHQEQVEDLTASHDAAL-LEMENNHTVAITILQDDHDHKVQELM 1181
+Q L + ++VED H A+ + E + V + +D D K +E+
Sbjct: 2155 ------ELEQALLVSADTFQKVED--RKHFGAVEAKPELSLEVQLQAERDAIDRKEKEIT 2206
Query: 1182 STHE-LE--KKELE---ENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRK---NTE 1232
+ E LE ++ELE E ++L + L+ Q T + Q L + F++ + K +
Sbjct: 2207 NLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIK 2266
Query: 1233 EQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQ 1292
E ++ L + Q E++ Q++EQ K+ + K+ N ++EEK ++++
Sbjct: 2267 ESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRD 2326
Query: 1293 QNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQE 1328
++ + V R EE L E +EK QE
Sbjct: 2327 LETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQE 2362
Score = 55.1 bits (131), Expect = 5e-07
Identities = 80/356 (22%), Positives = 158/356 (44%), Gaps = 57/356 (16%)
Query: 1016 EQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEKELSIELANIRDEVAFHT 1075
E +TR +GE++ A+ + + V N V EL+I+L + +
Sbjct: 462 EMKTRH----KGEMENALRSYSNITVNEDQIKLMN----VAINELNIKLQDTNSQKEKLK 513
Query: 1076 AKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQEEHG----- 1130
+ + +EK L+R+ ED V+ L + +E +R + + ++L E H
Sbjct: 514 EELGLILEEKCALQRQLEDLVEELSFS-----REQIQRARQTIAEQESKLNEAHKSLSTV 568
Query: 1131 DQLLSIRCQHQEQVEDLTASHDAAL------LEM-ENNHTVAITILQDDHDHKVQ----E 1179
+ L + E ++L H+A + LEM E + + + + +++ +
Sbjct: 569 EDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQ 628
Query: 1180 LMSTHELEKKELEE--------NFEKLRLSL----QDQVDTLTFQSQSLRDRARRFEEAL 1227
L+ +HE E +L+E N EKL+ +L + Q+D L S + +FE+
Sbjct: 629 LLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQ-NEMSQKIETMQFEKDN 687
Query: 1228 RKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKI 1287
+ QL + ++ + L++ + + K E QI+E +K+I L + ++ LE+++
Sbjct: 688 LITKQNQLILEISKLKDLQQSLVNSKS--EEMTLQINELQKEIEILRQEEKEKGTLEQEV 745
Query: 1288 QVLQQQNEDLKARIDQNTVVTRQLSEENANLQE---YVEKETQEKKRLSRTNEELL 1340
Q LQ + E ++ +Q+ E+ +LQE +E E K +T E++L
Sbjct: 746 QELQLKTE----------LLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDML 791
Score = 54.7 bits (130), Expect = 6e-07
Identities = 69/280 (24%), Positives = 127/280 (45%), Gaps = 41/280 (14%)
Query: 1082 QKEKEELERRFEDEVKRLGWQQQAELQELEERL--------QLQFEAEMARLQ-EEHGDQ 1132
Q E EEL R E+ G + +LQE E + QL + AR + +E +
Sbjct: 168 QHEIEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMRE 227
Query: 1133 LLSIRCQHQE---QVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELEKK 1189
L + Q Q+ Q + L AS L + + A +LQ K Q L +LE++
Sbjct: 228 FLELTEQSQKLQIQFQQLQASET---LRNSTHSSTAADLLQA----KQQILTHQQQLEEQ 280
Query: 1190 E-LEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEED 1248
+ L E+++K + + T Q L+++ + +E K E + E+
Sbjct: 281 DHLLEDYQKKK-------EDFTMQISFLQEKIKVYEMEQDKKVENSNK----------EE 323
Query: 1249 MKSLKQVLEMKNQQIHEQEKKILEL-EKLAEKNIILEEKIQVLQQQNED---LKARIDQN 1304
++ + ++E N +I E+EKK LEL +KL + +L E + + Q+N++ +K + +
Sbjct: 324 IQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNS 383
Query: 1305 TVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQ 1344
RQ SEE L VE+ + + S+ +++ +++
Sbjct: 384 KQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRME 423
Score = 53.9 bits (128), Expect = 1e-06
Identities = 89/388 (22%), Positives = 165/388 (42%), Gaps = 53/388 (13%)
Query: 1002 EAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDA--------------LAVATQHFF 1047
E+++Q L+L EQQ + L +Q +++ +DA L + +
Sbjct: 3250 ESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRI 3309
Query: 1048 RKNESALVKEKELSIELANIRDEVAFHTA-KCEKLQKE-KEELERRFEDEVKRLGWQQQA 1105
R+ S L +E+EL +L + E L KE +++LE + V+ L ++
Sbjct: 3310 REMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKY 3369
Query: 1106 ELQELEERLQLQFEAEMAR--LQEEHGDQLLSIRCQH--QEQVEDLTASHDAALLEMENN 1161
+L L+ R Q++ + ++ R LQ E + H Q +VEDL LE +
Sbjct: 3370 KLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQ-----LEEKRQ 3424
Query: 1162 HTVAITILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRAR 1221
+ D ++Q +M + ++ E EE E R+ Q+ + T+ S R R
Sbjct: 3425 QVYKL----DLEGQRLQGIMQEFQKQELEREEKRESRRILYQNLNEPTTWSLTSDRTRNW 3480
Query: 1222 RFEEALRKNTEEQLEIALAPYQ-------HLEEDMKSLKQVLEMKNQQIHEQEKKILELE 1274
++ + T+E L H E ++ Q + K Q + ++ + L+ E
Sbjct: 3481 VLQQKIEGETKESNYAKLIEMNGGGTGCNHELEMIRQKLQCVASKLQVLPQKASERLQFE 3540
Query: 1275 KLAEKNII-----LEEKIQVLQ----QQNEDLKARIDQNTV---VTRQLSEENANLQEYV 1322
+++ I ++E I LQ QQ E+ + + +T +T +L +NA L ++
Sbjct: 3541 TADDEDFIWVQENIDEIILQLQKLTGQQGEE-PSLVSPSTSCGSLTERLLRQNAELTGHI 3599
Query: 1323 EKETQEKKRL----SRTNEELLWKLQTG 1346
+ T+EK L + E++ W QTG
Sbjct: 3600 SQLTEEKNDLRNMVMKLEEQIRWYRQTG 3627
Score = 50.1 bits (118), Expect = 1e-05
Identities = 78/340 (22%), Positives = 148/340 (43%), Gaps = 44/340 (12%)
Query: 1004 ERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEKELSIE 1063
+++ RL+E EQ+ + +L AI DA++ QH + +++EKE+ I+
Sbjct: 2237 KKESTTRLQE-LEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEID 2295
Query: 1064 LAN-----IRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQF 1118
N ++ ++ T K+ +EK EL R E +++ L Q+ + EE ++ Q
Sbjct: 2296 QLNEQVTKLQQQLKITTD--NKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIE-QL 2352
Query: 1119 EAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQ 1178
+ +LQ+E L +I + L+ D+ H + + I +
Sbjct: 2353 NEVIEKLQQE----LANIGQKTSMNAHSLSEEADSL------KHQLDVVI--------AE 2394
Query: 1179 ELMSTHELEKKELEENFEKLRLSLQD-QVDTLTFQSQSLRDRARRFEEALRKNTEEQLEI 1237
+L ++E E F K L + +++ LT + SL+ R R E ++ E + +
Sbjct: 2395 KLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLK-RERESVEKIQSIPENSVNV 2453
Query: 1238 ALAPYQHLEEDMKSLKQVL------EMKNQQIHEQ-----EKKILELE-KLAEKNIILEE 1285
A+ HL +D L+ VL ++NQ + + I+ LE +L + +
Sbjct: 2454 AI---DHLSKDKPELEVVLTEDALKSLENQTYFKSFEENGKGSIINLETRLLQLESTVSA 2510
Query: 1286 KIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKE 1325
K L Q + +K +Q T L ++ NLQ+ VE++
Sbjct: 2511 KDLELTQCYKQIKDMQEQGQFETEMLQKKIVNLQKIVEEK 2550
Score = 43.5 bits (101), Expect = 0.001
Identities = 60/285 (21%), Positives = 116/285 (40%), Gaps = 35/285 (12%)
Query: 1079 EKLQKEKEELERR--FEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQEEHGDQLLSI 1136
E + + +LE + E+ R ++Q+ QE E L+ Q E +E + L++
Sbjct: 1859 EAISETSSQLEHAKVTQTELMRESFRQK---QEATESLKCQEELRERLHEESRAREQLAV 1915
Query: 1137 RCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELM-STHELEKKELEENF 1195
E V D A + L E + I D QEL+ +++ L++ E E+
Sbjct: 1916 ELSKAEGVIDGYAD-EKTLFERQIQEKTDII------DRLEQELLCASNRLQELEAEQQ- 1967
Query: 1196 EKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEEDMKSLKQV 1255
+Q++ + L+ Q ++++ A E+ L + TE+ ++ L E+ L++
Sbjct: 1968 -----QIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQ 2022
Query: 1256 LEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEEN 1315
++ + EQ + +ELE Q++N +L QN + +QL +
Sbjct: 2023 VKALEIDVEEQVSRFIELE----------------QEKNTELMDLRQQNQALEKQLEKMR 2066
Query: 1316 ANLQEYVEKETQEKKRLSRTNEELLWKLQTGDPTSPIKLSPTSPV 1360
L E E+ + ++L +L+ PI T V
Sbjct: 2067 KFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREV 2111
Score = 42.0 bits (97), Expect = 0.004
Identities = 55/253 (21%), Positives = 114/253 (45%), Gaps = 28/253 (11%)
Query: 1105 AELQELEERLQLQFEAEMARLQEEH-------GDQLLSIRCQHQEQVEDLTASHDAALLE 1157
+ L++L ++QLQ EAE+ + H G+ LL+++ E+ L A+ L
Sbjct: 2992 SSLKDLITKMQLQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTELTA 3051
Query: 1158 MENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKL-RLSLQDQVDTLTFQSQSL 1216
+ V L + + ++QE +E + E +K R SL ++ L Q
Sbjct: 3052 LGTTDAVG---LLNCLEQRIQE----QGVEYQAAMECLQKADRRSLLSEIQALHAQMNGR 3104
Query: 1217 RDRARRFEEALRKNTEEQLEIALAPYQ----HLEEDMKSLKQVLEMKNQQIHEQEKKILE 1272
+ +R +E+ K ++E LE + Q ++ ++ S+K +Q+ ++ + E
Sbjct: 3105 KITLKREQES-EKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAE 3163
Query: 1273 LE-KLAEKNIILEEKIQVLQQQNEDLKA-------RIDQNTVVTRQLSEENANLQEYVEK 1324
L+ +LA+ + LE ++ + ++L+A + D+ ++ L+ E +E
Sbjct: 3164 LKSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWA 3223
Query: 1325 ETQEKKRLSRTNE 1337
+EK +L R+ E
Sbjct: 3224 LEKEKAKLGRSEE 3236
Score = 36.6 bits (83), Expect = 0.17
Identities = 49/232 (21%), Positives = 93/232 (40%), Gaps = 27/232 (11%)
Query: 1112 ERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQD 1171
E + ++F+ E L +E G+ I + + D+ S D L E + T +
Sbjct: 1504 ETVDVKFKEEFKPLSKELGEHGKEILLSNSDP-HDIPESKDCVLTISEEMFSKDKTFIVR 1562
Query: 1172 DHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNT 1231
H + S + L E L+D L Q Q + +A +
Sbjct: 1563 QSIHDEISVSSMDASRQLMLNEE------QLEDMRQELVRQYQEHQQATELLRQAHMRQM 1616
Query: 1232 EEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQ 1291
E Q ED + L++ ++ N+Q+ Q I ++E+ +L E+++ L+
Sbjct: 1617 ERQ-----------REDQEQLQEEIKRLNRQL-AQRSSIDNENLVSERERVLLEELEALK 1664
Query: 1292 QQN----EDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEEL 1339
Q + E L + ++ T+ +E Q VE++T ++K L R E++
Sbjct: 1665 QLSLAGREKLCCELRNSSTQTQNGNEN----QGEVEEQTFKEKELDRKPEDV 1712
Score = 36.2 bits (82), Expect = 0.22
Identities = 70/316 (22%), Positives = 126/316 (39%), Gaps = 45/316 (14%)
Query: 1009 LRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEKELSIELANIR 1068
L L+++ E ++ + LK + L TQ F +L +E+E S+E
Sbjct: 2396 LALEQQVETANEEMTFMKNVLKETNFKMNQL---TQELF-----SLKRERE-SVEKIQSI 2446
Query: 1069 DEVAFHTAKCEKLQKEKEELERRF-EDEVKRLGWQQQAELQELEERLQ---LQFEAEMAR 1124
E + + A + L K+K ELE ED +K L + Q + EE + + E + +
Sbjct: 2447 PENSVNVA-IDHLSKDKPELEVVLTEDALKSL--ENQTYFKSFEENGKGSIINLETRLLQ 2503
Query: 1125 LQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTH 1184
L+ + L + Q +Q++D+ + E E + + + + L+S
Sbjct: 2504 LESTVSAKDLELT-QCYKQIKDM---QEQGQFETEMLQKKIVNLQKIVEEKVAAALVSQI 2559
Query: 1185 ELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQH 1244
+LE + F + D T S+ R + + +
Sbjct: 2560 QLEAVQEYAKFCQ---------DNQTISSEPERTNIQNLNQLREDELGSDISALTLRISE 2610
Query: 1245 LEEDMKSL-------KQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDL 1297
LE + + K+ +E+ + + E+EKK+LEL+KL E N EK +Q E
Sbjct: 2611 LESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGN----EK-----KQREKE 2661
Query: 1298 KARIDQNTVVTRQLSE 1313
K R Q+ V + +E
Sbjct: 2662 KKRSPQDVEVLKTTTE 2677
Score = 33.9 bits (76), Expect = 1.1
Identities = 45/229 (19%), Positives = 94/229 (41%), Gaps = 36/229 (15%)
Query: 1059 ELSIELANIRDEVAFHTAKCEKLQKEKEELERRFED-----------EVKRLGWQQQAEL 1107
+LS +L E++F + + L++EKE++ R + V+ Q + L
Sbjct: 961 DLSEQLKQKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINHNRAENVQSCDTQVSSLL 1020
Query: 1108 QELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAIT 1167
+ E ++++ + G++ I + + E++T ++ ++ +H ++T
Sbjct: 1021 DGVVTMTSRGAEGSVSKVNKSFGEES-KIMVEDKVSFENMTVGEESKQEQLILDHLPSVT 1079
Query: 1168 ILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEAL 1227
K L +T E +L++ L+ D L+ A+R +L
Sbjct: 1080 --------KESSLRATQPSENDKLQKELNVLKSEQNDL---------RLQMEAQRICLSL 1122
Query: 1228 RKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKL 1276
+T + Y E+D K + +K + I QE+KI EL+K+
Sbjct: 1123 VYSTHVD---QVREYMENEKD----KALCSLKEELIFAQEEKIKELQKI 1164
Score = 30.8 bits (68), Expect = 9.4
Identities = 54/284 (19%), Positives = 118/284 (41%), Gaps = 39/284 (13%)
Query: 1102 QQQAELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLE-MEN 1160
++ +L L+ RL + + ++ E G++ L +E+ E L+ LE ++
Sbjct: 1265 EEYNKLLVLQTRLSKIWGQQTDGMKLEFGEENLP-----KEETEFLSIHSQMTNLEDIDV 1319
Query: 1161 NHTVAITILQDDHDHKVQE-------LMSTHELEKKELEENFEKLRLSLQDQVDTLTFQ- 1212
NH ++ LQD K++E L+S+ + + KE E+N+E LQ ++ ++
Sbjct: 1320 NHKSKLSSLQDLEKTKLEEQVQELESLISSLQQQLKETEQNYEAEIHCLQKRLQAVSEST 1379
Query: 1213 ------------SQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKN 1260
++S R ++KN + +E + ++E+ +K + +
Sbjct: 1380 VPPSLPVDSVVITESDAQRTMYPGSCVKKNIDGTIE--FSGEFGVKEETNIVKLLEKQYQ 1437
Query: 1261 QQIHEQEKKILELEKLA-----EKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEEN 1315
+Q+ E+ K++ +A E + I K + + +Q+ +LS++
Sbjct: 1438 EQLEEEVAKVIVSMSIAFAQQTELSRISGGKENTASSKQAHAVCQQEQHYFNEMKLSQDQ 1497
Query: 1316 ANLQEYVEKETQEKKRLSRTNEELLWKLQTGDPTSPIKLSPTSP 1359
Q + + + K+ ++EL G+ I LS + P
Sbjct: 1498 IGFQTFETVDVKFKEEFKPLSKEL------GEHGKEILLSNSDP 1535
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 71.6 bits (174), Expect = 5e-12
Identities = 87/346 (25%), Positives = 158/346 (45%), Gaps = 52/346 (15%)
Query: 1049 KNESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRF----EDEVKRLGWQ-- 1102
K E E +EL + EV + K E L+KEK + R E E++RL Q
Sbjct: 572 KAEIVSASESRKELELKH-EAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLL 630
Query: 1103 --QQAELQELEERLQLQFEAEMARLQEEHG----DQLLSIRCQHQEQVEDLTASHDAALL 1156
+ EL +L+E L+++ + +L++ G Q+ ++ + +++E + D L+
Sbjct: 631 FSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDN-LI 689
Query: 1157 EMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKLRL------SLQDQVDTLT 1210
+N + I+ L+D V L+ EL++ E LR +L+ +V L
Sbjct: 690 TKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQ 749
Query: 1211 FQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKI 1270
+++ L + + E L++ QLE A L+++ K+L+ +L++ E+
Sbjct: 750 LKTELLEKQMKEKENDLQEKFA-QLE---AENSILKDEKKTLEDMLKIHTPVSQEERLIF 805
Query: 1271 LELEKLAEKNIILEEKIQVLQQQNEDLKAR-IDQNTVVTRQ-----LSEEN--ANLQEYV 1322
L+ K K+ + E++I++L ++NEDLK + I N + +Q +E+N N QE
Sbjct: 806 LDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQ 865
Query: 1323 E------------------KETQEKKRLSRTNEELLWKLQTGDPTS 1350
E +E + K +L NEEL LQ +PT+
Sbjct: 866 EEYACLLKVKDDLEDSKNKQELEYKSKLKALNEEL--HLQRINPTT 909
Score = 66.6 bits (161), Expect = 2e-10
Identities = 75/310 (24%), Positives = 146/310 (47%), Gaps = 33/310 (10%)
Query: 1055 VKEKE-LSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEER 1113
+KE E +E+ + DEV QK+ EL+ E E +LG ++ + +ELE+
Sbjct: 3178 LKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELED- 3236
Query: 1114 LQLQFEAEMAR-----LQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITI 1168
L+ E++ R L E QLL+ + Q+++E +DA L E E + + +
Sbjct: 3237 LKFSLESQKQRNLQLNLLLEQQKQLLN---ESQQKIESQRMLYDAQLSE-EQGRNLELQV 3292
Query: 1169 LQDDHDHKVQELMSTHELEKK-----ELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRF 1223
L + +++E+ ST + E++ + + + R L + D L + L ++ R
Sbjct: 3293 LLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSE-DLLKELQKQLEEKHSRI 3351
Query: 1224 EEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIIL 1283
E L + + +L+ +L Q +E+D + ++ L+ + + E +KK+ E L
Sbjct: 3352 VELLNETEKYKLD-SLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHE----------L 3400
Query: 1284 EEKIQVLQQQNEDLKARIDQNTVVTRQLS--EENANLQEYVEKETQEKKRL--SRTNEEL 1339
+ K++ LQ+Q E+ + ++ + + ++L + QE +E +E +R+ NE
Sbjct: 3401 QSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQNLNEPT 3460
Query: 1340 LWKLQTGDPT 1349
W L T D T
Sbjct: 3461 TWSL-TSDRT 3469
Score = 64.3 bits (155), Expect = 8e-10
Identities = 86/394 (21%), Positives = 165/394 (41%), Gaps = 57/394 (14%)
Query: 999 QAREAERQLVLR--LKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVK 1056
Q +EA L + L+ER +++R EL +A D A F R+ +
Sbjct: 1885 QKQEATESLKCQEELRERLHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDI 1944
Query: 1057 EKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELE----E 1112
L EL + + A+ +++Q+E+E L R+ E G +Q LQE E E
Sbjct: 1945 IDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKE 2004
Query: 1113 RLQLQFEAEMAR-----------------------LQEEHGDQLLSIRCQHQ---EQVED 1146
+L++Q +AE R L++E +L+ +R Q+Q +Q+E
Sbjct: 2005 KLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEK 2064
Query: 1147 LTASHDAALLEMENNHTVAITILQ---------------DDHDHKVQELMSTHELEKKEL 1191
+ D ++ E+ V +Q +H + E ++ H EK +
Sbjct: 2065 MRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDK 2124
Query: 1192 EENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQL-EIALAPYQHLEEDMK 1250
+ LQ + + + L R R E+AL + + P LE ++
Sbjct: 2125 CSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVEDRKHFGAVEAKPELSLEVQLQ 2184
Query: 1251 SLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQ 1310
+ + ++ K ++I E+ +LE+ E+ LE K + +QQ + L+ + ++T ++
Sbjct: 2185 AERDAIDRKEKEITNLEE---QLEQFREE---LENKNEEVQQLHMQLEIQKKESTTRLQE 2238
Query: 1311 LSEENANLQEYVEK---ETQEKKRLSRTNEELLW 1341
L +EN ++ +EK +E +S ++ +L+
Sbjct: 2239 LEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLF 2272
Score = 58.5 bits (140), Expect = 4e-08
Identities = 74/319 (23%), Positives = 150/319 (47%), Gaps = 39/319 (12%)
Query: 1028 ELKRAICGFDALAVATQH-FFRKNESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKE 1086
ELK + D L Q +KN+ K + +EL N + + + + ++L E
Sbjct: 347 ELKDKLTTADKLLGELQEQIVQKNQEI----KNMKLELTNSKQKERQSSEEIKQLMGTVE 402
Query: 1087 ELERR------FE-DEVKRLGWQQQAELQELEERLQLQFEAEMARLQEE----HGDQLLS 1135
EL++R FE D V+R+ + Q +L++L L + ++ ++++E H Q+
Sbjct: 403 ELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEE 462
Query: 1136 IRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENF 1195
++ +H+ ++E+ S+ + + + + I ++ + K+Q+ S E K+EL
Sbjct: 463 MKTRHKGEMENALRSYSNITVNEDQIKLMNVAI--NELNIKLQDTNSQKEKLKEELGLIL 520
Query: 1196 EKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEEDMKSLKQV 1255
E+ + +LQ Q++ L + R++ +R + + + + L E KSL V
Sbjct: 521 EE-KCALQRQLEDLVEELSFSREQIQRARQTIAEQESK-----------LNEAHKSLSTV 568
Query: 1256 LEMKNQQIHEQE-KKILELEKLAE-------KNIILEEKIQVLQQQNEDLKARIDQ-NTV 1306
++K + + E +K LEL+ AE ++ +EK VL + E +A +++ T
Sbjct: 569 EDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQ 628
Query: 1307 VTRQLSEENANLQEYVEKE 1325
+ EE + L+E +E E
Sbjct: 629 LLFSHEEELSKLKEDLEIE 647
Score = 57.0 bits (136), Expect = 1e-07
Identities = 65/275 (23%), Positives = 121/275 (44%), Gaps = 39/275 (14%)
Query: 1063 ELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQFEAEM 1122
E+ + + + T KC +L KE+L+R ++ + E+++LE R++ E E
Sbjct: 2110 EVEQLANHLKEKTDKCSELLLSKEQLQRDIQE--------RNEEIEKLEFRVR---ELEQ 2158
Query: 1123 ARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMS 1182
A L E+ +H VE + E + V + +D D K +E+ +
Sbjct: 2159 ALLVEDR---------KHFGAVE----------AKPELSLEVQLQAERDAIDRKEKEITN 2199
Query: 1183 THE-LE--KKELE---ENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRK---NTEE 1233
E LE ++ELE E ++L + L+ Q T + Q L + F++ + K +E
Sbjct: 2200 LEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKE 2259
Query: 1234 QLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQ 1293
++ L + Q E++ Q++EQ K+ + K+ N ++EEK ++++
Sbjct: 2260 SDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDL 2319
Query: 1294 NEDLKARIDQNTVVTRQLSEENANLQEYVEKETQE 1328
++ + V R EE L E +EK QE
Sbjct: 2320 ETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQE 2354
Score = 55.1 bits (131), Expect = 5e-07
Identities = 80/356 (22%), Positives = 158/356 (44%), Gaps = 57/356 (16%)
Query: 1016 EQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEKELSIELANIRDEVAFHT 1075
E +TR +GE++ A+ + + V N V EL+I+L + +
Sbjct: 462 EMKTRH----KGEMENALRSYSNITVNEDQIKLMN----VAINELNIKLQDTNSQKEKLK 513
Query: 1076 AKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQEEHG----- 1130
+ + +EK L+R+ ED V+ L + +E +R + + ++L E H
Sbjct: 514 EELGLILEEKCALQRQLEDLVEELSFS-----REQIQRARQTIAEQESKLNEAHKSLSTV 568
Query: 1131 DQLLSIRCQHQEQVEDLTASHDAAL------LEM-ENNHTVAITILQDDHDHKVQ----E 1179
+ L + E ++L H+A + LEM E + + + + +++ +
Sbjct: 569 EDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQ 628
Query: 1180 LMSTHELEKKELEE--------NFEKLRLSL----QDQVDTLTFQSQSLRDRARRFEEAL 1227
L+ +HE E +L+E N EKL+ +L + Q+D L S + +FE+
Sbjct: 629 LLFSHEEELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQ-NEMSQKIETMQFEKDN 687
Query: 1228 RKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKI 1287
+ QL + ++ + L++ + + K E QI+E +K+I L + ++ LE+++
Sbjct: 688 LITKQNQLILEISKLKDLQQSLVNSKS--EEMTLQINELQKEIEILRQEEKEKGTLEQEV 745
Query: 1288 QVLQQQNEDLKARIDQNTVVTRQLSEENANLQE---YVEKETQEKKRLSRTNEELL 1340
Q LQ + E ++ +Q+ E+ +LQE +E E K +T E++L
Sbjct: 746 QELQLKTE----------LLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDML 791
Score = 54.7 bits (130), Expect = 6e-07
Identities = 69/280 (24%), Positives = 127/280 (45%), Gaps = 41/280 (14%)
Query: 1082 QKEKEELERRFEDEVKRLGWQQQAELQELEERL--------QLQFEAEMARLQ-EEHGDQ 1132
Q E EEL R E+ G + +LQE E + QL + AR + +E +
Sbjct: 168 QHEIEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQARREKDETMRE 227
Query: 1133 LLSIRCQHQE---QVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELEKK 1189
L + Q Q+ Q + L AS L + + A +LQ K Q L +LE++
Sbjct: 228 FLELTEQSQKLQIQFQQLQASET---LRNSTHSSTAADLLQA----KQQILTHQQQLEEQ 280
Query: 1190 E-LEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEED 1248
+ L E+++K + + T Q L+++ + +E K E + E+
Sbjct: 281 DHLLEDYQKKK-------EDFTMQISFLQEKIKVYEMEQDKKVENSNK----------EE 323
Query: 1249 MKSLKQVLEMKNQQIHEQEKKILEL-EKLAEKNIILEEKIQVLQQQNED---LKARIDQN 1304
++ + ++E N +I E+EKK LEL +KL + +L E + + Q+N++ +K + +
Sbjct: 324 IQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNS 383
Query: 1305 TVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQ 1344
RQ SEE L VE+ + + S+ +++ +++
Sbjct: 384 KQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRME 423
Score = 53.9 bits (128), Expect = 1e-06
Identities = 89/388 (22%), Positives = 165/388 (42%), Gaps = 53/388 (13%)
Query: 1002 EAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDA--------------LAVATQHFF 1047
E+++Q L+L EQQ + L +Q +++ +DA L + +
Sbjct: 3242 ESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRI 3301
Query: 1048 RKNESALVKEKELSIELANIRDEVAFHTA-KCEKLQKE-KEELERRFEDEVKRLGWQQQA 1105
R+ S L +E+EL +L + E L KE +++LE + V+ L ++
Sbjct: 3302 REMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKY 3361
Query: 1106 ELQELEERLQLQFEAEMAR--LQEEHGDQLLSIRCQH--QEQVEDLTASHDAALLEMENN 1161
+L L+ R Q++ + ++ R LQ E + H Q +VEDL LE +
Sbjct: 3362 KLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQ-----LEEKRQ 3416
Query: 1162 HTVAITILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRAR 1221
+ D ++Q +M + ++ E EE E R+ Q+ + T+ S R R
Sbjct: 3417 QVYKL----DLEGQRLQGIMQEFQKQELEREEKRESRRILYQNLNEPTTWSLTSDRTRNW 3472
Query: 1222 RFEEALRKNTEEQLEIALAPYQ-------HLEEDMKSLKQVLEMKNQQIHEQEKKILELE 1274
++ + T+E L H E ++ Q + K Q + ++ + L+ E
Sbjct: 3473 VLQQKIEGETKESNYAKLIEMNGGGTGCNHELEMIRQKLQCVASKLQVLPQKASERLQFE 3532
Query: 1275 KLAEKNII-----LEEKIQVLQ----QQNEDLKARIDQNTV---VTRQLSEENANLQEYV 1322
+++ I ++E I LQ QQ E+ + + +T +T +L +NA L ++
Sbjct: 3533 TADDEDFIWVQENIDEIILQLQKLTGQQGEE-PSLVSPSTSCGSLTERLLRQNAELTGHI 3591
Query: 1323 EKETQEKKRL----SRTNEELLWKLQTG 1346
+ T+EK L + E++ W QTG
Sbjct: 3592 SQLTEEKNDLRNMVMKLEEQIRWYRQTG 3619
Score = 50.1 bits (118), Expect = 1e-05
Identities = 78/340 (22%), Positives = 148/340 (43%), Gaps = 44/340 (12%)
Query: 1004 ERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEKELSIE 1063
+++ RL+E EQ+ + +L AI DA++ QH + +++EKE+ I+
Sbjct: 2229 KKESTTRLQE-LEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEID 2287
Query: 1064 LAN-----IRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQF 1118
N ++ ++ T K+ +EK EL R E +++ L Q+ + EE ++ Q
Sbjct: 2288 QLNEQVTKLQQQLKITTD--NKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIE-QL 2344
Query: 1119 EAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQ 1178
+ +LQ+E L +I + L+ D+ H + + I +
Sbjct: 2345 NEVIEKLQQE----LANIGQKTSMNAHSLSEEADSL------KHQLDVVI--------AE 2386
Query: 1179 ELMSTHELEKKELEENFEKLRLSLQD-QVDTLTFQSQSLRDRARRFEEALRKNTEEQLEI 1237
+L ++E E F K L + +++ LT + SL+ R R E ++ E + +
Sbjct: 2387 KLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLK-RERESVEKIQSIPENSVNV 2445
Query: 1238 ALAPYQHLEEDMKSLKQVL------EMKNQQIHEQ-----EKKILELE-KLAEKNIILEE 1285
A+ HL +D L+ VL ++NQ + + I+ LE +L + +
Sbjct: 2446 AI---DHLSKDKPELEVVLTEDALKSLENQTYFKSFEENGKGSIINLETRLLQLESTVSA 2502
Query: 1286 KIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKE 1325
K L Q + +K +Q T L ++ NLQ+ VE++
Sbjct: 2503 KDLELTQCYKQIKDMQEQGQFETEMLQKKIVNLQKIVEEK 2542
Score = 43.5 bits (101), Expect = 0.001
Identities = 60/285 (21%), Positives = 116/285 (40%), Gaps = 35/285 (12%)
Query: 1079 EKLQKEKEELERR--FEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQEEHGDQLLSI 1136
E + + +LE + E+ R ++Q+ QE E L+ Q E +E + L++
Sbjct: 1859 EAISETSSQLEHAKVTQTELMRESFRQK---QEATESLKCQEELRERLHEESRAREQLAV 1915
Query: 1137 RCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELM-STHELEKKELEENF 1195
E V D A + L E + I D QEL+ +++ L++ E E+
Sbjct: 1916 ELSKAEGVIDGYAD-EKTLFERQIQEKTDII------DRLEQELLCASNRLQELEAEQQ- 1967
Query: 1196 EKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEEDMKSLKQV 1255
+Q++ + L+ Q ++++ A E+ L + TE+ ++ L E+ L++
Sbjct: 1968 -----QIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQ 2022
Query: 1256 LEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEEN 1315
++ + EQ + +ELE Q++N +L QN + +QL +
Sbjct: 2023 VKALEIDVEEQVSRFIELE----------------QEKNTELMDLRQQNQALEKQLEKMR 2066
Query: 1316 ANLQEYVEKETQEKKRLSRTNEELLWKLQTGDPTSPIKLSPTSPV 1360
L E E+ + ++L +L+ PI T V
Sbjct: 2067 KFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREV 2111
Score = 42.0 bits (97), Expect = 0.004
Identities = 55/253 (21%), Positives = 114/253 (45%), Gaps = 28/253 (11%)
Query: 1105 AELQELEERLQLQFEAEMARLQEEH-------GDQLLSIRCQHQEQVEDLTASHDAALLE 1157
+ L++L ++QLQ EAE+ + H G+ LL+++ E+ L A+ L
Sbjct: 2984 SSLKDLITKMQLQREAEVYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTELTA 3043
Query: 1158 MENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKL-RLSLQDQVDTLTFQSQSL 1216
+ V L + + ++QE +E + E +K R SL ++ L Q
Sbjct: 3044 LGTTDAVG---LLNCLEQRIQE----QGVEYQAAMECLQKADRRSLLSEIQALHAQMNGR 3096
Query: 1217 RDRARRFEEALRKNTEEQLEIALAPYQ----HLEEDMKSLKQVLEMKNQQIHEQEKKILE 1272
+ +R +E+ K ++E LE + Q ++ ++ S+K +Q+ ++ + E
Sbjct: 3097 KITLKREQES-EKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAE 3155
Query: 1273 LE-KLAEKNIILEEKIQVLQQQNEDLKA-------RIDQNTVVTRQLSEENANLQEYVEK 1324
L+ +LA+ + LE ++ + ++L+A + D+ ++ L+ E +E
Sbjct: 3156 LKSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWA 3215
Query: 1325 ETQEKKRLSRTNE 1337
+EK +L R+ E
Sbjct: 3216 LEKEKAKLGRSEE 3228
Score = 36.6 bits (83), Expect = 0.17
Identities = 49/232 (21%), Positives = 93/232 (40%), Gaps = 27/232 (11%)
Query: 1112 ERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQD 1171
E + ++F+ E L +E G+ I + + D+ S D L E + T +
Sbjct: 1504 ETVDVKFKEEFKPLSKELGEHGKEILLSNSDP-HDIPESKDCVLTISEEMFSKDKTFIVR 1562
Query: 1172 DHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNT 1231
H + S + L E L+D L Q Q + +A +
Sbjct: 1563 QSIHDEISVSSMDASRQLMLNEE------QLEDMRQELVRQYQEHQQATELLRQAHMRQM 1616
Query: 1232 EEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQ 1291
E Q ED + L++ ++ N+Q+ Q I ++E+ +L E+++ L+
Sbjct: 1617 ERQ-----------REDQEQLQEEIKRLNRQL-AQRSSIDNENLVSERERVLLEELEALK 1664
Query: 1292 QQN----EDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEEL 1339
Q + E L + ++ T+ +E Q VE++T ++K L R E++
Sbjct: 1665 QLSLAGREKLCCELRNSSTQTQNGNEN----QGEVEEQTFKEKELDRKPEDV 1712
Score = 36.2 bits (82), Expect = 0.22
Identities = 70/316 (22%), Positives = 126/316 (39%), Gaps = 45/316 (14%)
Query: 1009 LRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEKELSIELANIR 1068
L L+++ E ++ + LK + L TQ F +L +E+E S+E
Sbjct: 2388 LALEQQVETANEEMTFMKNVLKETNFKMNQL---TQELF-----SLKRERE-SVEKIQSI 2438
Query: 1069 DEVAFHTAKCEKLQKEKEELERRF-EDEVKRLGWQQQAELQELEERLQ---LQFEAEMAR 1124
E + + A + L K+K ELE ED +K L + Q + EE + + E + +
Sbjct: 2439 PENSVNVA-IDHLSKDKPELEVVLTEDALKSL--ENQTYFKSFEENGKGSIINLETRLLQ 2495
Query: 1125 LQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTH 1184
L+ + L + Q +Q++D+ + E E + + + + L+S
Sbjct: 2496 LESTVSAKDLELT-QCYKQIKDM---QEQGQFETEMLQKKIVNLQKIVEEKVAAALVSQI 2551
Query: 1185 ELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQH 1244
+LE + F + D T S+ R + + +
Sbjct: 2552 QLEAVQEYAKFCQ---------DNQTISSEPERTNIQNLNQLREDELGSDISALTLRISE 2602
Query: 1245 LEEDMKSL-------KQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDL 1297
LE + + K+ +E+ + + E+EKK+LEL+KL E N EK +Q E
Sbjct: 2603 LESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGN----EK-----KQREKE 2653
Query: 1298 KARIDQNTVVTRQLSE 1313
K R Q+ V + +E
Sbjct: 2654 KKRSPQDVEVLKTTTE 2669
Score = 33.9 bits (76), Expect = 1.1
Identities = 45/229 (19%), Positives = 94/229 (41%), Gaps = 36/229 (15%)
Query: 1059 ELSIELANIRDEVAFHTAKCEKLQKEKEELERRFED-----------EVKRLGWQQQAEL 1107
+LS +L E++F + + L++EKE++ R + V+ Q + L
Sbjct: 961 DLSEQLKQKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINHNRAENVQSCDTQVSSLL 1020
Query: 1108 QELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAIT 1167
+ E ++++ + G++ I + + E++T ++ ++ +H ++T
Sbjct: 1021 DGVVTMTSRGAEGSVSKVNKSFGEES-KIMVEDKVSFENMTVGEESKQEQLILDHLPSVT 1079
Query: 1168 ILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEAL 1227
K L +T E +L++ L+ D L+ A+R +L
Sbjct: 1080 --------KESSLRATQPSENDKLQKELNVLKSEQNDL---------RLQMEAQRICLSL 1122
Query: 1228 RKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKL 1276
+T + Y E+D K + +K + I QE+KI EL+K+
Sbjct: 1123 VYSTHVD---QVREYMENEKD----KALCSLKEELIFAQEEKIKELQKI 1164
Score = 30.8 bits (68), Expect = 9.4
Identities = 54/284 (19%), Positives = 118/284 (41%), Gaps = 39/284 (13%)
Query: 1102 QQQAELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLE-MEN 1160
++ +L L+ RL + + ++ E G++ L +E+ E L+ LE ++
Sbjct: 1265 EEYNKLLVLQTRLSKIWGQQTDGMKLEFGEENLP-----KEETEFLSIHSQMTNLEDIDV 1319
Query: 1161 NHTVAITILQDDHDHKVQE-------LMSTHELEKKELEENFEKLRLSLQDQVDTLTFQ- 1212
NH ++ LQD K++E L+S+ + + KE E+N+E LQ ++ ++
Sbjct: 1320 NHKSKLSSLQDLEKTKLEEQVQELESLISSLQQQLKETEQNYEAEIHCLQKRLQAVSEST 1379
Query: 1213 ------------SQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKN 1260
++S R ++KN + +E + ++E+ +K + +
Sbjct: 1380 VPPSLPVDSVVITESDAQRTMYPGSCVKKNIDGTIE--FSGEFGVKEETNIVKLLEKQYQ 1437
Query: 1261 QQIHEQEKKILELEKLA-----EKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEEN 1315
+Q+ E+ K++ +A E + I K + + +Q+ +LS++
Sbjct: 1438 EQLEEEVAKVIVSMSIAFAQQTELSRISGGKENTASSKQAHAVCQQEQHYFNEMKLSQDQ 1497
Query: 1316 ANLQEYVEKETQEKKRLSRTNEELLWKLQTGDPTSPIKLSPTSP 1359
Q + + + K+ ++EL G+ I LS + P
Sbjct: 1498 IGFQTFETVDVKFKEEFKPLSKEL------GEHGKEILLSNSDP 1535
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 70.5 bits (171), Expect = 1e-11
Identities = 81/353 (22%), Positives = 169/353 (47%), Gaps = 53/353 (15%)
Query: 1027 GELKRAICGFDALAVATQHFFRKNE---SALVKEKE-LSIEL--------------ANIR 1068
GEL+RA+ AV+T+H +K + L KE++ LS+EL A ++
Sbjct: 179 GELQRALS-----AVSTRH--KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQ 231
Query: 1069 DEVAFHTAKCEKLQKEKEELERRFE-----------DEVKRLGWQQQAELQELEERLQLQ 1117
+++ ++ ++Q +EL+R+ E + ++ W+Q+ EL+E E++++ Q
Sbjct: 232 EKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQ 291
Query: 1118 FEAEMARLQEEHGDQLLSIRCQHQE--QVEDLTASHDAALLEMENNHTVAITIL-QDDHD 1174
E +M R +E +Q +R Q ++ + E + L E E + Q++
Sbjct: 292 -EEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQM 350
Query: 1175 HKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRF---EEALRKNT 1231
+ +E M E + +E EE + L +Q + Q Q +RD+ R +E LR+
Sbjct: 351 QEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE 410
Query: 1232 EEQLEIALAPYQHLEEDMKSLKQVLEMKNQQ--IHEQEKKILELEKLAEKNIILEEKIQV 1289
E E + + E ++ +++ +M+ Q+ +QE+K+ E E++ E+ + E+ +
Sbjct: 411 ERMRE-----QEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEET 465
Query: 1290 LQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWK 1342
+++Q E ++ + ++N + + L E EK +++K + EE +W+
Sbjct: 466 MREQEEKMQKQ-EENMWEQEEKEWQQQRLPEQKEKLWEQEK--MQEQEEKIWE 515
Score = 67.8 bits (164), Expect = 7e-11
Identities = 65/304 (21%), Positives = 144/304 (47%), Gaps = 22/304 (7%)
Query: 1048 RKNESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAEL 1107
R E + +E+ + +R+E + EK+QK++E + + E E WQQQ L
Sbjct: 440 RDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE-----WQQQ-RL 493
Query: 1108 QELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAIT 1167
E +E+L Q +M +E+ +Q IR Q + ++ + E E+
Sbjct: 494 PEQKEKLWEQ--EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEE 551
Query: 1168 ILQD------DHDHKV------QELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQS 1215
++D D + ++ QE + + EK EE + ++++ + + Q +
Sbjct: 552 KMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK 611
Query: 1216 LRDRARRFEEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQ-IHEQEKKILELE 1274
++++ + +E K E++ ++ + E++ K +Q +M QQ + EQ++K+ E E
Sbjct: 612 MQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHE 671
Query: 1275 KLAEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSR 1334
K+ E+ + E++ ++ +Q+ + K + + ++ E +++E EK+ +E++ + R
Sbjct: 672 KMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRER-EKKMREEEEMMR 730
Query: 1335 TNEE 1338
EE
Sbjct: 731 EQEE 734
Score = 58.5 bits (140), Expect = 4e-08
Identities = 73/353 (20%), Positives = 163/353 (46%), Gaps = 45/353 (12%)
Query: 1001 REAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEKEL 1060
RE E ++ R ++R +Q ++L + EL+ Q R+ E + +++E
Sbjct: 310 REQEEKM-WRQEKRLREQEKELREQEKELRE------------QKELREQEEQMQEQEEK 356
Query: 1061 SIELAN-IRDEVAFHTAKCEKL---QKEKEELERRFEDEVKRLGWQQQAELQELEERLQL 1116
E +R++ + E+L +K+ E E++ D+ +R+ W+Q L+E EER++
Sbjct: 357 MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM-WEQDERLREKEERMRE 415
Query: 1117 QFEA--EMARLQEEHGDQLLSIRCQHQE---QVEDLTASHDAALLEMENNHTVAITILQD 1171
Q + ++ +++EE Q + + QE Q E+ + + E E +Q
Sbjct: 416 QEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQK 475
Query: 1172 DHDHKVQELMSTHELEKKELEENFEKL--RLSLQDQVDTLTFQSQSLRDRARRFEEALRK 1229
++ ++ E +++ L E EKL + +Q+Q + + Q + +RD+ + + +
Sbjct: 476 QEENMWEQ--EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM 533
Query: 1230 NTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQV 1289
+E+ M+ + + + +++ +QE+K+ + E+ EK +EK
Sbjct: 534 WRQEK--------------MREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTW 579
Query: 1290 LQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWK 1342
Q++ + R+ + +++ EE ++E EK QE++ + EE +W+
Sbjct: 580 DQEEKMREEERMRER---EKKMREEEEMMREQEEK-MQEQEEKMQEQEEKMWE 628
Score = 54.7 bits (130), Expect = 6e-07
Identities = 71/293 (24%), Positives = 128/293 (43%), Gaps = 51/293 (17%)
Query: 1051 ESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQEL 1110
E + +E+ + +R+E + EK+Q+++E+++ E E K W+Q+ ++QE
Sbjct: 582 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQ---EQEEKM--WEQEEKMQEQ 636
Query: 1111 EERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQ 1170
EE++ Q E +M +E+ +Q + EQ E L
Sbjct: 637 EEKMWEQ-EEKMWEQEEKMWEQQ-----RLPEQKEKLW---------------------- 668
Query: 1171 DDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKN 1230
+H+ K+QE E E+K E+ EK+ Q+Q Q + + + R E +
Sbjct: 669 -EHE-KMQEQEKMQEQEEKIWEQ--EKMEKKTQEQEKKTWDQEKMREEESMREREKKMRE 724
Query: 1231 TEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIIL--EEKIQ 1288
EE + Q EE M+ ++ + + +++ EQE+K+ E ++L E+ L EK+Q
Sbjct: 725 EEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ 784
Query: 1289 VLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLW 1341
++ E + DQ EE QE + +EK R EE +W
Sbjct: 785 EQEKIWEQEEKMRDQ---------EEKMRGQEEKMRGQEEK---MRGQEEKMW 825
Score = 52.8 bits (125), Expect = 2e-06
Identities = 70/361 (19%), Positives = 157/361 (43%), Gaps = 75/361 (20%)
Query: 995 KPDPQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESAL 1054
+ + + RE E++ + + +E+ +Q +L +G+++ + +R+ +
Sbjct: 276 RQEEELREQEKK-IRKQEEKMWRQEERLREQEGKMREQ----------EEKMWRQEKRLR 324
Query: 1055 VKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERL 1114
+EKEL + +R+ QKE E E + +++ +++ W+Q+ +++E EE++
Sbjct: 325 EQEKELREQEKELRE------------QKELREQEEQMQEQEEKM-WEQEEKMREQEEKM 371
Query: 1115 QLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHD 1174
Q E + +++ +Q +R Q + E QD+
Sbjct: 372 WRQ-EERLWEQEKQMREQEQKMRDQEERMWE------------------------QDERL 406
Query: 1175 HKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQ 1234
+ +E M E++++ E EK+R + Q Q + RD+ + +E EE+
Sbjct: 407 REKEERMR----EQEKMWEQVEKMREEKKMQE-----QEKKTRDQEEKMQE------EER 451
Query: 1235 LEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIIL---------EE 1285
+ + EE M+ ++ ++ + + + EQE+K + ++L E+ L EE
Sbjct: 452 IREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE 511
Query: 1286 KIQVLQQQNEDLKARIDQNTVVTRQ--LSEENANLQEYVEKETQEKKRLSRTNEELLWKL 1343
KI +++ D + Q + RQ + E+ + E EK +++++ E + K
Sbjct: 512 KIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKT 571
Query: 1344 Q 1344
Q
Sbjct: 572 Q 572
Score = 40.4 bits (93), Expect = 0.012
Identities = 53/224 (23%), Positives = 103/224 (45%), Gaps = 37/224 (16%)
Query: 1079 EKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQEEHGDQLLSIRC 1138
EK++K+ +E E++ D+ K +++ ++E E++++ E EM R QEE
Sbjct: 690 EKMEKKTQEQEKKTWDQEKM---REEESMREREKKMRE--EEEMMREQEE---------- 734
Query: 1139 QHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHEL--EKKELEENFE 1196
+ QEQ E + + + E + + + +E + HE E++++ E E
Sbjct: 735 KMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEE 794
Query: 1197 KLRLSLQDQVDTLTFQSQSLR---DRARRFEEALRKNTEE----------QLEIALAPYQ 1243
K+R DQ + + Q + +R ++ R EE + E+ Q E +
Sbjct: 795 KMR----DQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEE 850
Query: 1244 HLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKI 1287
+EE M+ ++ + + +++ QE+K+ E E EK EEKI
Sbjct: 851 KMEEKMQGQEEKMREQEEKMRGQEEKMREQE---EKMRGQEEKI 891
Score = 38.5 bits (88), Expect = 0.045
Identities = 50/231 (21%), Positives = 99/231 (42%), Gaps = 49/231 (21%)
Query: 1044 QHFFRKNESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEEL----ERRFEDEVKRL 1099
Q R+ ES +EK++ E +R++ + EK+Q+++EE+ E+ +E E K
Sbjct: 706 QEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKM- 764
Query: 1100 GWQQQAELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEME 1159
W+QQ L E +E+L +E E + QE+ +Q +E++ D
Sbjct: 765 -WEQQ-RLPEQKEKL---WEHEKMQEQEKIWEQ--------EEKMRD------------- 798
Query: 1160 NNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDR 1219
Q++ +E M E + + EE + Q + + Q + + +
Sbjct: 799 ----------QEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQ 848
Query: 1220 ARRFEEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKI 1270
+ EE ++ E+ E EE M+ ++ + + +++ QE+KI
Sbjct: 849 EEKMEEKMQGQEEKMRE--------QEEKMRGQEEKMREQEEKMRGQEEKI 891
Score = 36.6 bits (83), Expect = 0.17
Identities = 41/176 (23%), Positives = 74/176 (42%), Gaps = 19/176 (10%)
Query: 1187 EKKELEENFEKLRLSLQDQVDT---LTFQSQSL-------RDRARRFEEALRKNTEEQLE 1236
EKK ++ E LR ++ Q T LT Q L +D AR+FE+ T
Sbjct: 82 EKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDG-NLGTPSSFN 140
Query: 1237 IALA------PYQHLEEDM--KSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQ 1288
+AL+ P + + K + + H + L ++ ++ + I+
Sbjct: 141 LALSQAFRGSPLGCVSTSLIPGESKDLAGRLHHSWHFAGELQRALSAVSTRHKKADRYIE 200
Query: 1289 VLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQ 1344
L ++ + L + +NT+ +L ++NA LQE + EK + +EL KL+
Sbjct: 201 ELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLE 256
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A member
6-like protein 6 [Homo sapiens]
Length = 655
Score = 70.1 bits (170), Expect = 1e-11
Identities = 84/356 (23%), Positives = 162/356 (45%), Gaps = 44/356 (12%)
Query: 1001 REAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEKEL 1060
+ AE Q LRL E E+ QL V +LKR + + L+ +++L
Sbjct: 219 KNAELQEKLRLVES-EKSEIQLNVK--DLKRKL---------------ERAQLLLPQQQL 260
Query: 1061 SIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQF-- 1118
+E + E+ +AK + Q E+ EL + + W+Q+ ++QE EE++ Q
Sbjct: 261 QVEADRLGKELQSVSAKLQA-QVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELK 319
Query: 1119 ----EAEMARLQEEHGDQLLSIRCQHQE--QVEDLTASHDAALLEMENNHTVAITILQDD 1172
E +M R +E+ +Q IR Q + + E+ + + E E +++
Sbjct: 320 IREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQ 379
Query: 1173 HDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRAR---RFEEALRK 1229
D K+QE +++++ E EK + + Q + Q + +R++ R EE +R+
Sbjct: 380 -DEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRE 438
Query: 1230 ------NTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIIL 1283
+ EE+L Q EE M+ ++ ++ + ++I EQE+K EKL ++
Sbjct: 439 LEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ---- 494
Query: 1284 EEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEEL 1339
EEKI +Q E + + ++ ++ E+ +Q EK +++ RL + E++
Sbjct: 495 EEKI---WEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKM 547
Score = 66.2 bits (160), Expect = 2e-10
Identities = 114/510 (22%), Positives = 217/510 (42%), Gaps = 79/510 (15%)
Query: 884 PEQGRPATRSTFGNEEQPVL------------KASLPSKDTPKGAGRVAPPASSSVTAPR 931
PE A S F + PVL K SK KG G+ + + +
Sbjct: 6 PEVSERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADEKFFQ 65
Query: 932 RSLLPAPKSTSTPAGTKK----DAQKDQDTNKPAVSSPKRVAASTTK---LHSPG--YPK 982
S + A GTK+ D ++ + +K S KRV + + G + K
Sbjct: 66 LSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVK 125
Query: 983 QRTAAARNGFPPKPDPQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVA 1042
+ + ++ F + Q + E+ R + ++ +LG + + ++L
Sbjct: 126 KNSDEVKSSFKKR---QEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPE----NSLLEE 178
Query: 1043 TQHFFRKNESA-----LVKEKEL-SIEL-------ANIRDEVAFHTAKCEKLQKEKEELE 1089
T HF L KE++ S+EL ++++ A K ++ EK E++
Sbjct: 179 TLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQ 238
Query: 1090 RRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTA 1149
+D ++L ++A+L L + QLQ EA+ G +L S+ + Q QVE+
Sbjct: 239 LNVKDLKRKL---ERAQL--LLPQQQLQVEADRL------GKELQSVSAKLQAQVEE--- 284
Query: 1150 SHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENF----EKL---RLSL 1202
L + N Q++ + +E M EL+ +E EE EK+ +
Sbjct: 285 ---NELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKI 341
Query: 1203 QDQVDTLTFQSQSLRDRARRFEEALRK--NTEEQLEIALAPYQHLEEDM----KSLKQVL 1256
++Q D + Q + +R++ + E K EE++ Q EE+M + +++
Sbjct: 342 REQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQE 401
Query: 1257 EMKNQQIHEQEKKILEL-EKLAEKNIIL---EEKIQVLQQQNEDLKARIDQNTVVTRQLS 1312
E + +++ QEKK+ E EK+ E+ + EEKI+ L++ +D + ++ + V ++
Sbjct: 402 EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLRE---VEEKMQ 458
Query: 1313 EENANLQEYVEKETQEKKRLSRTNEELLWK 1342
EE +QE EK ++++++ + EE W+
Sbjct: 459 EEEEKMQEQEEKIQRQEEKI-QEQEEKTWR 487
Score = 33.5 bits (75), Expect = 1.4
Identities = 24/80 (30%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Query: 111 SSTIQRELNEEHTVERGTDSLQTTRSIQGPSLSSWRNVMSEASLDVLAKRDAEIPRHVPK 170
+S ++ L+ +H V GT + T+ PSL +RN +++ L E R V
Sbjct: 173 NSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVES 232
Query: 171 DKLAKTLDNEELRRHSLERA 190
+K L+ ++L+R LERA
Sbjct: 233 EKSEIQLNVKDLKR-KLERA 251
Score = 31.6 bits (70), Expect = 5.5
Identities = 19/78 (24%), Positives = 37/78 (47%)
Query: 1267 EKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKET 1326
E +LE + + + I+ L ++ + + +NT+ +L E+NA LQE +
Sbjct: 172 ENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVE 231
Query: 1327 QEKKRLSRTNEELLWKLQ 1344
EK + ++L KL+
Sbjct: 232 SEKSEIQLNVKDLKRKLE 249
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A member
6-like protein 6 [Homo sapiens]
Length = 655
Score = 70.1 bits (170), Expect = 1e-11
Identities = 84/356 (23%), Positives = 162/356 (45%), Gaps = 44/356 (12%)
Query: 1001 REAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEKEL 1060
+ AE Q LRL E E+ QL V +LKR + + L+ +++L
Sbjct: 219 KNAELQEKLRLVES-EKSEIQLNVK--DLKRKL---------------ERAQLLLPQQQL 260
Query: 1061 SIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQF-- 1118
+E + E+ +AK + Q E+ EL + + W+Q+ ++QE EE++ Q
Sbjct: 261 QVEADRLGKELQSVSAKLQA-QVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELK 319
Query: 1119 ----EAEMARLQEEHGDQLLSIRCQHQE--QVEDLTASHDAALLEMENNHTVAITILQDD 1172
E +M R +E+ +Q IR Q + + E+ + + E E +++
Sbjct: 320 IREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQ 379
Query: 1173 HDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRAR---RFEEALRK 1229
D K+QE +++++ E EK + + Q + Q + +R++ R EE +R+
Sbjct: 380 -DEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRE 438
Query: 1230 ------NTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIIL 1283
+ EE+L Q EE M+ ++ ++ + ++I EQE+K EKL ++
Sbjct: 439 LEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ---- 494
Query: 1284 EEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEEL 1339
EEKI +Q E + + ++ ++ E+ +Q EK +++ RL + E++
Sbjct: 495 EEKI---WEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKM 547
Score = 68.2 bits (165), Expect = 5e-11
Identities = 115/510 (22%), Positives = 218/510 (42%), Gaps = 79/510 (15%)
Query: 884 PEQGRPATRSTFGNEEQPVL------------KASLPSKDTPKGAGRVAPPASSSVTAPR 931
PE A S F + PVL K SK KG G+ + + +
Sbjct: 6 PEVSERANSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADEKFFQ 65
Query: 932 RSLLPAPKSTSTPAGTKK----DAQKDQDTNKPAVSSPKRVAASTTK---LHSPG--YPK 982
S + A GTK+ D ++ + +K S KRV + + G + K
Sbjct: 66 LSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVK 125
Query: 983 QRTAAARNGFPPKPDPQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVA 1042
+ + ++ F + Q + E+ R + ++ +LG + + ++L
Sbjct: 126 KNSDEVKSSFKKR---QEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPE----NSLLEE 178
Query: 1043 TQHFFRKNESA-----LVKEKE-LSIEL-------ANIRDEVAFHTAKCEKLQKEKEELE 1089
T HF L KE++ LS+EL ++++ A K ++ EK E++
Sbjct: 179 TLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQ 238
Query: 1090 RRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTA 1149
+D ++L ++A+L L + QLQ EA+ G +L S+ + Q QVE+
Sbjct: 239 LNVKDLKRKL---ERAQL--LLPQQQLQVEADRL------GKELQSVSAKLQAQVEE--- 284
Query: 1150 SHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENF----EKL---RLSL 1202
L + N Q++ + +E M EL+ +E EE EK+ +
Sbjct: 285 ---NELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKI 341
Query: 1203 QDQVDTLTFQSQSLRDRARRFEEALRK--NTEEQLEIALAPYQHLEEDM----KSLKQVL 1256
++Q D + Q + +R++ + E K EE++ Q EE+M + +++
Sbjct: 342 REQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQE 401
Query: 1257 EMKNQQIHEQEKKILEL-EKLAEKNIIL---EEKIQVLQQQNEDLKARIDQNTVVTRQLS 1312
E + +++ QEKK+ E EK+ E+ + EEKI+ L++ +D + ++ + V ++
Sbjct: 402 EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLRE---VEEKMQ 458
Query: 1313 EENANLQEYVEKETQEKKRLSRTNEELLWK 1342
EE +QE EK ++++++ + EE W+
Sbjct: 459 EEEEKMQEQEEKIQRQEEKI-QEQEEKTWR 487
Score = 34.3 bits (77), Expect = 0.85
Identities = 20/78 (25%), Positives = 38/78 (48%)
Query: 1267 EKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKET 1326
E +LE + + + I+ L ++ + L + +NT+ +L E+NA LQE +
Sbjct: 172 ENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVE 231
Query: 1327 QEKKRLSRTNEELLWKLQ 1344
EK + ++L KL+
Sbjct: 232 SEKSEIQLNVKDLKRKLE 249
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 70.1 bits (170), Expect = 1e-11
Identities = 76/300 (25%), Positives = 140/300 (46%), Gaps = 49/300 (16%)
Query: 1070 EVAFHTAK---CEKLQKE-----KEELERRFEDEVKRLGWQQQAELQELEERLQ--LQFE 1119
E HT + C+K + E ++ R+FED LG E ++L RL F
Sbjct: 88 EAQDHTIRILTCQKTELETALYYSQDAARKFEDG--NLG-----ESKDLAGRLHHSWHFA 140
Query: 1120 AEMARLQEEHGDQLLSIRCQHQEQ---VEDLTASHDAALLEMENNHTVAITILQDDHDHK 1176
E+ R L ++ H++ +E+LT DA LE+ N TI ++ K
Sbjct: 141 GELQRA-------LSAVSTWHKKADRYIEELTKERDALSLELYRN-----TITNEELKKK 188
Query: 1177 ---VQELMSTHELEKKELEENFEKLRLSLQ------DQVDTLTFQSQSLR--DRARRFEE 1225
+QE + E EK E++ N ++L+ L+ QV T T Q + R + R E+
Sbjct: 189 NAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEK 248
Query: 1226 ALRKNTE------EQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEK 1279
+RK E E+L + EE M+ ++ L + +++ EQEK++ E +KL E+
Sbjct: 249 KIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQ 308
Query: 1280 NIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEEL 1339
++E+ + + +Q E ++ + ++ +L E+ ++E +K +++R+ +E L
Sbjct: 309 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL 368
Score = 65.1 bits (157), Expect = 4e-10
Identities = 75/352 (21%), Positives = 166/352 (47%), Gaps = 26/352 (7%)
Query: 997 DPQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVK 1056
+ + RE E++L R +++ +Q Q+ Q + ++ + + + +R+ E +
Sbjct: 289 EKELREQEKEL--REQKKLREQEEQM---QEQEEKMWEQEEKMREQEEKMWRQEERLWEQ 343
Query: 1057 EKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERL-- 1114
EK++ + +RD+ + E+L++++E R ++ K W+Q+ ++QE EER+
Sbjct: 344 EKQMREQEQKMRDQEERMWEQDERLREKEE----RMREQEKM--WEQEEKMQE-EERIRE 396
Query: 1115 ---QLQFEAEMARLQEEHGDQLLSIRCQHQEQ--VEDLTASHDAALLEMENNHTVAITIL 1169
+++ E E R QEE + + +E+ + L E E I
Sbjct: 397 REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 456
Query: 1170 QDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRF---EEA 1226
+ + + QE M E +K +E + + +Q + + Q Q + D+ R +E
Sbjct: 457 EQEEKIRDQEEMWGQE-KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER 515
Query: 1227 LRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEK 1286
LR+ E E Q EE M+ K+ E + ++ +QE+K+ E E++ E+ + E+
Sbjct: 516 LREKEERMREQKKMWQQ--EEKMREEKKTQE-QEKKTWDQEEKMREEERMREREKKMREE 572
Query: 1287 IQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEE 1338
+++++Q E ++ + ++ ++ E+ +QE EK ++++++ EE
Sbjct: 573 EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEE 624
Score = 63.5 bits (153), Expect = 1e-09
Identities = 65/309 (21%), Positives = 150/309 (48%), Gaps = 24/309 (7%)
Query: 1048 RKNESALVKEKELSIELANIRDEVAFHTAKCEKL--QKEKEELERRFEDEVKRLGWQQQA 1105
++ E +EK++ E +R++ + E + Q+EKE ++R ++ ++L W+Q+
Sbjct: 389 QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL-WEQE- 446
Query: 1106 ELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVA 1165
++QE EE++ Q E ++ +E G + R + + ED + + + E
Sbjct: 447 KMQEQEEKIWEQ-EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 505
Query: 1166 ITIL--QDDHDHKVQELMSTHELEKKELEENFEKLR--LSLQDQVDTLTFQSQSLRDRAR 1221
+ QD+ + +E M E+K++ + EK+R Q+Q Q + +R+ R
Sbjct: 506 EERMWEQDERLREKEERMR----EQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEER 561
Query: 1222 --------RFEEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILEL 1273
R EE + + EE+++ + EE M ++ ++ + +++ EQE+K+ E
Sbjct: 562 MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 621
Query: 1274 E---KLAEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKK 1330
E K+ E+ ++ E+ + +Q+Q E + + ++ ++ E+ +Q EK ++++
Sbjct: 622 EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE 681
Query: 1331 RLSRTNEEL 1339
++ E++
Sbjct: 682 KMQGQEEKM 690
Score = 62.0 bits (149), Expect = 4e-09
Identities = 75/353 (21%), Positives = 157/353 (44%), Gaps = 36/353 (10%)
Query: 1001 REAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVKEKEL 1060
RE E ++ R ++R +Q ++L + EL+ Q R+ E + +++E
Sbjct: 272 REQEEKM-RRQEKRLREQEKELREQEKELRE------------QKKLREQEEQMQEQEEK 318
Query: 1061 SIELAN-IRDEVAFHTAKCEKL---QKEKEELERRFEDEVKRLGWQQQAELQELEERLQL 1116
E +R++ + E+L +K+ E E++ D+ +R+ W+Q L+E EER++
Sbjct: 319 MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM-WEQDERLREKEERMRE 377
Query: 1117 QFEA--EMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHD 1174
Q + + ++QEE + + R + + E+ + + + E N Q++ +
Sbjct: 378 QEKMWEQEEKMQEE---ERIREREKKMREEEETMREQEEKMQKQEENMWE-----QEEKE 429
Query: 1175 HKVQELMSTHEL--EKKELEENFEKL---RLSLQDQVDTLTFQSQSLRDRARRFEEALRK 1229
+ Q L E E+++++E EK+ ++DQ + + + R R +E
Sbjct: 430 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 489
Query: 1230 NTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQV 1289
EE++ EE M + L K +++ EQ+K + EK+ E+ E++ +
Sbjct: 490 EQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKT 549
Query: 1290 LQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWK 1342
Q+ K R ++ + E + E++ QE++ R EE +W+
Sbjct: 550 WDQEE---KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE 599
Score = 60.8 bits (146), Expect = 8e-09
Identities = 64/310 (20%), Positives = 146/310 (47%), Gaps = 30/310 (9%)
Query: 1055 VKEKELSIELAN-IRDEVAFHTAKCEKLQKEKE--ELERRFEDEVKRLGWQQQAELQELE 1111
VKE + +E A + +V +T + E ++E+E E E++ + +++ W+Q+ L+E E
Sbjct: 210 VKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKM-WRQEERLREQE 268
Query: 1112 ERLQLQFEAEMARLQEEHGDQLLSIRCQHQE--------QVEDLTASHDAALLEMENNHT 1163
+++ Q E +M R ++ +Q +R Q +E + E+ + + E E
Sbjct: 269 GKMREQ-EEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMR 327
Query: 1164 VAITILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRF 1223
Q++ + +E + E + +E E+ + +Q + L + + +R++ + +
Sbjct: 328 E-----QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMW 382
Query: 1224 EEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIIL 1283
E+ + EE++ + EE M+ ++ ++ + + + EQE+K + ++L E+ L
Sbjct: 383 EQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL 442
Query: 1284 ---------EEKIQVLQQQNEDLKARIDQNTVVTRQ--LSEENANLQEYVEKETQEKKRL 1332
EEKI +++ D + Q + RQ + E+ + E EK +++++
Sbjct: 443 WEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM 502
Query: 1333 SRTNEELLWK 1342
EE +W+
Sbjct: 503 -WDQEERMWE 511
Score = 50.8 bits (120), Expect = 9e-06
Identities = 53/232 (22%), Positives = 108/232 (46%), Gaps = 27/232 (11%)
Query: 1082 QKEKEELERRFEDEVKRLGWQQQAELQELEERLQ-----LQFEAEMARLQEEHGDQLLSI 1136
Q+EK E++ +++ K+ W Q+ +++E EER++ ++ E EM R QEE
Sbjct: 532 QEEKMREEKKTQEQEKKT-WDQEEKMRE-EERMREREKKMREEEEMMREQEE-------- 581
Query: 1137 RCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELEKK--ELEEN 1194
+ QEQ E + + + E Q++ + +E M E E K E EE
Sbjct: 582 --KMQEQEEKMREQEEKMWEQEEKMQE------QEEKMWEQEEKMWEQEEEDKMQEQEEM 633
Query: 1195 FEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRK--NTEEQLEIALAPYQHLEEDMKSL 1252
+ +Q+Q + + Q + +R++ + E K EE++ Q EE M+
Sbjct: 634 MWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQ 693
Query: 1253 KQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQN 1304
++ + + +++ QE+K+ E+ + EK + ++ Q E ++ R+ ++
Sbjct: 694 EEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEH 745
Score = 37.4 bits (85), Expect = 0.10
Identities = 43/170 (25%), Positives = 70/170 (41%), Gaps = 31/170 (18%)
Query: 1185 ELEKKELEENFEKLRLSLQDQVDT---LTFQSQSL-------RDRARRFEEALRKNTEEQ 1234
E EKK ++ E LR ++ Q T LT Q L +D AR+FE+ N E
Sbjct: 70 EDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDG---NLGES 126
Query: 1235 LEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQN 1294
++A H L++ L + + ++ I EL K +
Sbjct: 127 KDLA-GRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTK-----------------ER 168
Query: 1295 EDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQ 1344
+ L + +NT+ +L ++NA LQE + EK + +EL KL+
Sbjct: 169 DALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLE 218
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 70.1 bits (170), Expect = 1e-11
Identities = 76/352 (21%), Positives = 168/352 (47%), Gaps = 28/352 (7%)
Query: 997 DPQAREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDALAVATQHFFRKNESALVK 1056
+ + RE E + + +E+ +Q + + +++R + + + R+ E + +
Sbjct: 381 EEKIREQEEK-IREQEEKMRRQEEMMWEKEEKMRRQ----EEMMWEKEEKMRRQEEMMWE 435
Query: 1057 EKELSIELANIRDEVAFHTAKCEKLQKEKE--ELERRFEDEVKRLGWQQQAELQELEERL 1114
++E EL E + EK Q+E++ E E+R E E K W+Q+ +++E EE++
Sbjct: 436 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM--WRQEEKIREQEEKI 493
Query: 1115 QLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHD 1174
+ Q E +M R QEE + IR + + Q ++ + + E E Q +
Sbjct: 494 REQ-EEKMWR-QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR------QKEKI 545
Query: 1175 HKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTE-- 1232
H+ +E + E + EE +++Q + + Q + +R++ EE +R+ E
Sbjct: 546 HEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQ----EEKIREQEEKI 601
Query: 1233 -EQLEIALAPYQHL---EEDMKSLKQVLEMKNQQIHEQEKKILELE-KLAEKNIILEEKI 1287
EQ E+ + + EE M ++ ++ + +++ QE+KI E E K+ E+ + E+
Sbjct: 602 REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE 661
Query: 1288 QVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEEL 1339
+++Q+Q E + + ++ ++ E+ ++ EK +++ RL + E++
Sbjct: 662 EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 713
Score = 67.8 bits (164), Expect = 7e-11
Identities = 72/335 (21%), Positives = 153/335 (45%), Gaps = 44/335 (13%)
Query: 1048 RKNESA--LVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQA 1105
RK E A L+ +++L E ++ E+ +AK + Q E+ EL R + + W+Q+
Sbjct: 310 RKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQA-QVEENELWNRLNQQQEEKMWRQEE 368
Query: 1106 ELQELEERLQLQFE------------AEMARLQEE----------HGDQLLSIRCQHQEQ 1143
++QE EE++Q Q E E R QEE ++++ + + +
Sbjct: 369 KIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 428
Query: 1144 VEDLTASHDAALLEMENNHTVAITILQDD----HDHKVQELMSTHELEKK--ELEENFEK 1197
E++ + + E+E I + + + K++E E E K EE +
Sbjct: 429 QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 488
Query: 1198 LRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTE----------EQLEIALAPYQHLEE 1247
+++Q + + Q + + ++ + EE R+ E EQ EI + E+
Sbjct: 489 QEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQ 548
Query: 1248 DMKSLKQVLEM--KNQQIHEQEKKILEL-EKLAEKNIILEEKIQVLQQQNEDLKARIDQN 1304
+ K KQ +M + +++H+QE+KI E EK+ + + E+ + +++Q E ++ + +
Sbjct: 549 EEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMT 608
Query: 1305 TVVTRQLSEENANLQEYVEKETQEKKRLSRTNEEL 1339
++ E+ + E EK ++++++ R E++
Sbjct: 609 QEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI 643
Score = 64.3 bits (155), Expect = 8e-10
Identities = 62/256 (24%), Positives = 125/256 (48%), Gaps = 27/256 (10%)
Query: 1048 RKNESALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAEL 1107
R+ E + +++E E IR+E EK Q+++E + + + W+Q+ ++
Sbjct: 494 REQEEKMWRQEEKIHEQEKIREE--------EKRQEQEEMWRQEEKIREQEEIWRQKEKI 545
Query: 1108 QELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAIT 1167
E EE+++ Q E +M R +E+ DQ IR Q E+ + + E E
Sbjct: 546 HEQEEKIRKQ-EEKMWRQEEKMHDQEEKIREQ-----EEKVWRQEEKIREQEEK------ 593
Query: 1168 ILQDDHDHKVQELMSTHELEKK-ELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEA 1226
I + + + QE M+ + EK E EE + +Q+Q + + Q + +R++ ++ E
Sbjct: 594 IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQ 653
Query: 1227 LRKNTEEQLEIALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKIL-ELEKLAEKNIILEE 1285
K E++ + Q EE M ++ + + +++ EQE+K+ + EK+ E+ + L +
Sbjct: 654 EEKIREQEEMM-----QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 708
Query: 1286 KIQVLQQQNEDLKARI 1301
+ + +Q+ E L+A I
Sbjct: 709 QEEKMQEHQEHLEAAI 724
Score = 44.3 bits (103), Expect = 8e-04
Identities = 60/275 (21%), Positives = 119/275 (43%), Gaps = 56/275 (20%)
Query: 1070 EVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQ--LQFEAEMARLQE 1127
E HT + QK + ++ + + Q + E ++L RL +F E+ E
Sbjct: 187 EAQVHTIRILTCQKTELQMALYYSQHAVK---QLEGEARDLISRLHDSWKFAGEL----E 239
Query: 1128 EHGDQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELE 1187
+ + + + + +E+LT DA LE+ N T+ L++ + K+QE + E E
Sbjct: 240 QALSAVATQKKKADRYIEELTKERDALSLELYRN-TITDEELKEKNA-KLQEKLQLVESE 297
Query: 1188 KKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEE 1247
K E++ N ++L+ R+ E A ++QL+ A HL +
Sbjct: 298 KSEIQLNVKELK---------------------RKLERAKLLLPQQQLQ---AEADHLGK 333
Query: 1248 DMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQNTVV 1307
+++S+ L+ Q+ E E ++ EK EEKIQ +++
Sbjct: 334 ELQSVSAKLQA---QVEENELWNRLNQQQEEKMWRQEEKIQEWEEK-------------- 376
Query: 1308 TRQLSEENANLQEYVEKETQEKKRLSRTNEELLWK 1342
+ E+ ++E EK ++++++ R EE++W+
Sbjct: 377 ---IQEQEEKIREQEEKIREQEEKMRR-QEEMMWE 407
Score = 43.1 bits (100), Expect = 0.002
Identities = 41/164 (25%), Positives = 75/164 (45%), Gaps = 23/164 (14%)
Query: 1185 ELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQH 1244
E E+K ++ E LR L+ QV T+ R T ++ E+ +A Y +
Sbjct: 169 EDEQKASHQHQEALRRELEAQVHTI------------------RILTCQKTELQMALY-Y 209
Query: 1245 LEEDMKSLKQVLEMKNQQIHEQEKKILELEK----LAEKNIILEEKIQVLQQQNEDLKAR 1300
+ +K L+ ++H+ K ELE+ +A + + I+ L ++ + L
Sbjct: 210 SQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLE 269
Query: 1301 IDQNTVVTRQLSEENANLQEYVEKETQEKKRLSRTNEELLWKLQ 1344
+ +NT+ +L E+NA LQE ++ EK + +EL KL+
Sbjct: 270 LYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLE 313
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 70.1 bits (170), Expect = 1e-11
Identities = 74/299 (24%), Positives = 140/299 (46%), Gaps = 44/299 (14%)
Query: 1053 ALVKEKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEE 1112
A +K E ++ +D+ +K EK+Q+ +E+L + E+E+ RL Q++ L L E
Sbjct: 590 AALKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRE 649
Query: 1113 RLQLQFEAEMARLQEEHGDQLLSIRCQHQEQV----EDLTASHDAALLEMENNHTVAITI 1168
RLQ E E AR++EE +L +R Q Q + + A +A+L ++
Sbjct: 650 RLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLR--------- 700
Query: 1169 LQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALR 1228
+EL S + E+ LE+ ++ L+++++ Q+ + A+ E+AL+
Sbjct: 701 ---------EELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAK--EKALQ 749
Query: 1229 KNTEEQLE------IALAPYQHLEEDMKSLKQVLEMKNQQ-IHEQEKKILELEKLAEKNI 1281
+ EQLE +A +H E ++ L LE K+++ + +KKI E ++ E
Sbjct: 750 Q-LREQLEGERKEAVATLEKEHSAE-LERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQ- 806
Query: 1282 ILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANL--QEYVEKETQEKKRLSRTNEE 1338
LQ+ ++ R+ Q + E ++L ++ E E + ++RL + EE
Sbjct: 807 --------LQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEE 857
Score = 64.3 bits (155), Expect = 8e-10
Identities = 86/385 (22%), Positives = 171/385 (44%), Gaps = 61/385 (15%)
Query: 1002 EAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDA------------LAVATQHFFRK 1049
+ E + +LRL ++ EQ L + L++AI +A L Q +
Sbjct: 627 QEEEEEILRLHQQKEQSLSSL---RERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQA 683
Query: 1050 NESALVKEKELSIELANIRDEV---------AFHTAKCEKLQKEKEELERRFEDEVKRLG 1100
+E + E+E S++ +R+E+ + + L++ KEE+E + E L
Sbjct: 684 DEDQIRAEQEASLQ--KLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALN 741
Query: 1101 WQQQAELQELEERLQLQFEAEMARLQEEHGDQL----LSIRCQHQEQVEDL--------- 1147
++ LQ+L E+L+ + + +A L++EH +L S+ +H+E V L
Sbjct: 742 AAKEKALQQLREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQ 801
Query: 1148 --TASHDAALLEMENN-HTVAITILQDDHD------HKVQELMSTHELEKKELEENFEKL 1198
A L ++E+ H + + +H+ K QE+ HE +++E +++
Sbjct: 802 KEEAQLQKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQV 861
Query: 1199 RLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEEDMKSLKQVLEM 1258
++Q ++++ + RA E L T E + A + LE + + LE
Sbjct: 862 MAKAREQ-----YEAEERKQRA----ELLGHLTGELERLQRAHERELETVRQEQHKRLED 912
Query: 1259 KNQQIHEQEKKILELE-KLAEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQL---SEE 1314
++ EQE+K+ +LE L + ++ ++ +L+ Q E + Q V RQ+ SEE
Sbjct: 913 LRRRHREQERKLQDLELDLETRAKDVKARLALLEVQEETARREKQQLLDVQRQVALKSEE 972
Query: 1315 NANLQEYVEKETQEKKRLSRTNEEL 1339
+ +E+ +E L ++N++L
Sbjct: 973 ATATHQQLEEAQKEHTHLLQSNQQL 997
Score = 62.0 bits (149), Expect = 4e-09
Identities = 193/905 (21%), Positives = 329/905 (36%), Gaps = 124/905 (13%)
Query: 491 TEVPEPLDPQSGRSEARESKEVTTSVAENRNLLENADKIESTSARADSVLNIPAPLHPET 550
T +P + ++ +E+ E T E + E A K A A + A E
Sbjct: 329 TPKADPTGSEPAKASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEGSSDASQELEI 388
Query: 551 TVNMTYQPTTPSSSFQDVSVFGMDAGSPLVVPPPTDSARLLNTSPKVPDKNTCPSGIPKP 610
+ +M + S + S G+D G + S LL+ P +P
Sbjct: 389 SEHMKEPQLSDSIASDPKSFHGLDFGFRSRI-----SEHLLDVDVLSPVLGGACRQAQQP 443
Query: 611 VFTHSKD-TPSSQEGMENYQVEKTEERTETKPIIMPKPKHVRPKIITYIRRNPQALGQVD 669
+ KD + SSQ+ +++ Q + EER P P R +
Sbjct: 444 LGIEDKDDSQSSQDELQSKQSKGLEERLSP-----PLPHEERAQ---------------- 482
Query: 670 ASLVPVGLPYAPPTCTMPLPHEEKAAGGDLKPSANLYEKFKPDLQKPRVFSSGLMVSGIK 729
+PP EE G + +P E+ D L
Sbjct: 483 ----------SPPRSLAT--EEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAP 530
Query: 730 PPGHPFSQMSEKFLQEVTDHPGKEEFCSPPYAHYEVPPT-----FYRSAMLLKP--QLGL 782
P + E+ Q PG+EE P V PT RS + P QL
Sbjct: 531 SPPAACEKGKEQHSQAEELGPGQEE-AEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSE 589
Query: 783 GAMSRLPSAKSRILIASQRSSASAIHPPGPITTATSLYSSDPSADLK----KASSSNAAK 838
A+ + A +++L QR + L + L+ K S ++ +
Sbjct: 590 AALKAMEEAVAQVLEQDQRHLLESKQEKMQ-QLREKLCQEEEEEILRLHQQKEQSLSSLR 648
Query: 839 SNLPKSGLRPPGYSRLPAAKLAAFGFVRSSSVSSVSSTQSGDSAQPEQGRPATRSTFGNE 898
L K+ +R+ + ++R+ SS + + A+ E R
Sbjct: 649 ERLQKAIEEEE--ARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREEL-ES 705
Query: 899 EQPVLKASLPSKDTPKGAGRVAPPASSSVTAPRRSLLPAPKSTSTPAGTKKDAQKDQDTN 958
+Q +ASL K+ ++ + A +S A + A + Q + +
Sbjct: 706 QQKAERASLEQKNR-----QMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERK 760
Query: 959 KPAVSSPKRVAASTTKLHSPGYPKQRTAAARNGFPPKPDPQAREAERQLVL-RLKERCEQ 1017
+ + K +A +L S K R + + Q EA+ Q L +++ R Q
Sbjct: 761 EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQ 820
Query: 1018 QTRQLGVAQGELKRAICGFDALAVATQHFFR------KNESALVKEKE-LSIELANIRDE 1070
++ + + EL ++ V +H R +++ + K +E E R E
Sbjct: 821 KSYHVAGYEHELS-SLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAE 879
Query: 1071 VAFH-TAKCEKLQKEKE--------ELERRFEDEVKRLGWQQQAELQELEERLQLQFEAE 1121
+ H T + E+LQ+ E E +R ED ++R +Q+ +LQ+LE L+ + +
Sbjct: 880 LLGHLTGELERLQRAHERELETVRQEQHKRLED-LRRRHREQERKLQDLELDLETRAKDV 938
Query: 1122 MARL-----QEEHG----DQLLSIRCQHQEQVEDLTASHDAALLEMENNHTVAITILQDD 1172
ARL QEE QLL ++ Q + E+ TA+H ++E Q +
Sbjct: 939 KARLALLEVQEETARREKQQLLDVQRQVALKSEEATATHQ----QLEE--------AQKE 986
Query: 1173 HDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQ-------SLRDRARRFEE 1225
H H +Q S +L +E+ + + +L L+ QVD L QSQ SL A++ +
Sbjct: 987 HTHLLQ---SNQQL--REILDELQARKLKLESQVDLLQAQSQQLQKHFSSLEAEAQKKQH 1041
Query: 1226 ALRKNTEEQLEIA--LAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKN--- 1280
LR+ T E+ + P H+E+ KSL + Q K+ L L+ L+ N
Sbjct: 1042 LLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKEVSSSLSQSKEDLYLDSLSSHNVWH 1101
Query: 1281 ------IILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKETQEKKRLSR 1334
+ L + L QQ ++ R + E A+ QE V K+ K L
Sbjct: 1102 LLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQHWRHELASAQE-VAKDPPGIKALED 1160
Query: 1335 TNEEL 1339
+ L
Sbjct: 1161 MRKNL 1165
Score = 38.1 bits (87), Expect = 0.059
Identities = 103/476 (21%), Positives = 185/476 (38%), Gaps = 81/476 (17%)
Query: 941 TSTPAGTKKDAQKDQDTNKPAVSSPKRVAASTTKLHS------------PGYP------K 982
TS P KKD D D P + + L S PG P K
Sbjct: 260 TSQPE-EKKDVSLDSDAAGPPTPCKPSSPGADSSLSSAVGKGRQGSGARPGLPEKEENEK 318
Query: 983 QRTAAARNGFPPKPDPQ----AREAERQLVLRLKERCEQQTRQLGVAQGELKRAICGFDA 1038
RN PK DP A+ +E++ + E+ +R+ A+ K+A +
Sbjct: 319 SEPKICRNLVTPKADPTGSEPAKASEKEAPEDTVDAGEEGSRREEAAKEPKKKASALEEG 378
Query: 1039 LAVATQHFFRKNESALVKEKELSIELAN-----------IRDEVAFHTAKCEKLQKEKEE 1087
+ A+Q S +KE +LS +A+ R ++ H + L
Sbjct: 379 SSDASQEL---EISEHMKEPQLSDSIASDPKSFHGLDFGFRSRISEHLLDVDVLSPVLGG 435
Query: 1088 LERRFED----EVKRLGWQQQAELQE-----LEERL--------QLQFEAEMARLQEE-- 1128
R+ + E K Q ELQ LEERL + Q +EE
Sbjct: 436 ACRQAQQPLGIEDKDDSQSSQDELQSKQSKGLEERLSPPLPHEERAQSPPRSLATEEEPP 495
Query: 1129 HGDQLLSIRCQHQEQVEDLTASHDAAL-LEMENNHTVAITILQDDHDHKVQELMSTHELE 1187
G + + +E ED AS L L+ E + + H E + +
Sbjct: 496 QGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQ-- 553
Query: 1188 KKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLEIALAPYQHLEE 1247
+E E+ EK+ +S V ++ + + E AL+ E ++ +HL E
Sbjct: 554 -EEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPEQLSEAALKAMEEAVAQVLEQDQRHLLE 612
Query: 1248 DMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNI----------ILEEKIQVLQQQNED- 1296
+ Q +++ + E+E++IL L + E+++ I EE+ ++ +++++
Sbjct: 613 SKQEKMQ--QLREKLCQEEEEEILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRL 670
Query: 1297 --LKARIDQNTVVTRQ--LSEENANLQEYVEK-ETQEKKR---LSRTNEELLWKLQ 1344
L+A++ +T +E+ A+LQ+ E+ E+Q+K L + N ++L +L+
Sbjct: 671 SWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLK 726
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.126 0.350
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,420,637
Number of Sequences: 37866
Number of extensions: 3273548
Number of successful extensions: 23707
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 226
Number of HSP's successfully gapped in prelim test: 1530
Number of HSP's that attempted gapping in prelim test: 14228
Number of HSP's gapped (non-prelim): 7188
length of query: 1379
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1264
effective length of database: 13,892,928
effective search space: 17560660992
effective search space used: 17560660992
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.