Guide to the Human Genome
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Search of human proteins with 7661914

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7661914 proteasome (prosome, macropain) 26S subunit,
non-ATPase, 6 [Homo sapiens]
         (389 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7661914 proteasome (prosome, macropain) 26S subunit, non-ATPa...   776   0.0  
gi|47078238 G protein pathway suppressor 1 isoform 1 [Homo sapiens]   100   2e-21
gi|47078240 G protein pathway suppressor 1 isoform 2 [Homo sapiens]    98   1e-20
gi|38044112 restin isoform b [Homo sapiens]                            34   0.20 
gi|4506751 restin isoform a [Homo sapiens]                             34   0.20 
gi|70995235 AMMECR1 protein isoform 2 [Homo sapiens]                   34   0.26 
gi|7669554 AMMECR1 protein isoform 1 [Homo sapiens]                    34   0.26 
gi|219842262 COP9 constitutive photomorphogenic homolog subunit ...    33   0.34 
gi|4759264 COP9 constitutive photomorphogenic homolog subunit 2 ...    33   0.34 
gi|4506221 proteasome 26S non-ATPase subunit 12 isoform 1 [Homo ...    32   0.75 
gi|28872765 proteasome 26S non-ATPase subunit 12 isoform 2 [Homo...    32   0.75 
gi|92859701 myosin VI [Homo sapiens]                                   31   2.2  
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...    30   2.8  
gi|7657138 golgi integral membrane protein 4 [Homo sapiens]            30   2.8  
gi|226495417 coiled-coil domain containing 102A [Homo sapiens]         30   3.7  
gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]       30   3.7  
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...    30   3.7  
gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]       30   3.7  
gi|13899233 tetratricopeptide repeat domain 25 [Homo sapiens]          30   3.7  
gi|82659109 retinoblastoma-associated factor 600 [Homo sapiens]        30   3.7  
gi|4502175 apical protein of Xenopus-like [Homo sapiens]               30   4.9  
gi|6857820 phosphatidylinositol-5-phosphate 4-kinase, type II, a...    29   6.3  
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]           29   6.3  
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]           29   6.3  
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]           29   6.3  
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo...    29   6.3  
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof...    29   6.3  
gi|31982906 cingulin-like 1 [Homo sapiens]                             29   6.3  
gi|55769583 progesterone-induced blocking factor 1 [Homo sapiens]      29   6.3  
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]                    29   8.3  

>gi|7661914 proteasome (prosome, macropain) 26S subunit, non-ATPase,
           6 [Homo sapiens]
          Length = 389

 Score =  776 bits (2003), Expect = 0.0
 Identities = 389/389 (100%), Positives = 389/389 (100%)

Query: 1   MPLENLEEEGLPKNPDLRIAQLRFLLSLPEHRGDAAVRDELMAAVRDNNMAPYYEALCKS 60
           MPLENLEEEGLPKNPDLRIAQLRFLLSLPEHRGDAAVRDELMAAVRDNNMAPYYEALCKS
Sbjct: 1   MPLENLEEEGLPKNPDLRIAQLRFLLSLPEHRGDAAVRDELMAAVRDNNMAPYYEALCKS 60

Query: 61  LDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCRIGDKEGA 120
           LDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCRIGDKEGA
Sbjct: 61  LDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCRIGDKEGA 120

Query: 121 LTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRL 180
           LTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRL
Sbjct: 121 LTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRL 180

Query: 181 KVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKV 240
           KVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKV
Sbjct: 181 KVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKV 240

Query: 241 IKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAPHYRYYVREMR 300
           IKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAPHYRYYVREMR
Sbjct: 241 IKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAPHYRYYVREMR 300

Query: 301 IHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPD 360
           IHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPD
Sbjct: 301 IHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPD 360

Query: 361 SKNWQYQETIKKGDLLLNRVQKLSRVINM 389
           SKNWQYQETIKKGDLLLNRVQKLSRVINM
Sbjct: 361 SKNWQYQETIKKGDLLLNRVQKLSRVINM 389


>gi|47078238 G protein pathway suppressor 1 isoform 1 [Homo sapiens]
          Length = 527

 Score =  100 bits (249), Expect = 2e-21
 Identities = 87/384 (22%), Positives = 170/384 (44%), Gaps = 17/384 (4%)

Query: 15  PDLRIAQLRFLLSLPEHRGDAAVRDE----LMAAVRDNNMAPYYEALCKS--LDWQIDVD 68
           P LR+  L+  LS  +   +  + +E    L  A R+   AP  +A+ +S      +D  
Sbjct: 108 PTLRVEALKMALSFVQRTFNVDMYEEIHRKLSEATRELQNAP--DAIPESGVEPPALDTA 165

Query: 69  LLNKMKKANEDELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCRIGDKEGALTAFRKTY 128
            +   +K    +L++LD +L++ + N  +  IR       ++    GD   AL  + +  
Sbjct: 166 WVEATRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCYSRAR 225

Query: 129 DKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKS---LIEEGGDWDRRN-----RL 180
           D   +  H +++   ++++ ++  +   +     KA+S   + E+ G+ D +      +L
Sbjct: 226 DYCTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQTQAILTKL 285

Query: 181 KVYQGLYCVAIRDFKQAAE-LFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREK 239
           K   GL  +A R +KQAA+ L L +       EL+       Y    ++   +R +L+  
Sbjct: 286 KCAAGLAELAARKYKQAAKCLLLASFDHCDFPELLSPSNVAIYGGLCALATFDRQELQRN 345

Query: 240 VIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAPHYRYYVREM 299
           VI  +     L   P VR  +F  YE +Y+   + L  ++  +  D   APH R    ++
Sbjct: 346 VISSSSFKLFLELEPQVRDIIFKFYESKYASCLKMLDEMKDNLLLDMYLAPHVRTLYTQI 405

Query: 300 RIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRP 359
           R  A  Q    Y S  +  MA AF   V  ++ EL++ I  G +  ++D  ++I+     
Sbjct: 406 RNRALIQYFSPYVSADMHRMAAAFNTTVAALEDELTQLILEGLISARVDSHSKILYARDV 465

Query: 360 DSKNWQYQETIKKGDLLLNRVQKL 383
           D ++  +++++  G     R + +
Sbjct: 466 DQRSTTFEKSLLMGKEFQRRAKAM 489


>gi|47078240 G protein pathway suppressor 1 isoform 2 [Homo sapiens]
          Length = 491

 Score = 98.2 bits (243), Expect = 1e-20
 Identities = 85/388 (21%), Positives = 172/388 (44%), Gaps = 21/388 (5%)

Query: 15  PDLRIAQLRFLLSLPEHRGDAAVRDEL--------MAAVRDNNMAPYYEALCKS--LDWQ 64
           P LR+  L+  LS  +   +  + +E+         +++R+   AP  +A+ +S      
Sbjct: 68  PTLRVEALKMALSFVQRTFNVDMYEEIHRKLSEATRSSLRELQNAP--DAIPESGVEPPA 125

Query: 65  IDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCRIGDKEGALTAF 124
           +D   +   +K    +L++LD +L++ + N  +  IR       ++    GD   AL  +
Sbjct: 126 LDTAWVEATRKKALLKLEKLDTDLKNYKGNSIKESIRRGHDDLGDHYLDCGDLSNALKCY 185

Query: 125 RKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKS---LIEEGGDWDRRN--- 178
            +  D   +  H +++   ++++ ++  +   +     KA+S   + E+ G+ D +    
Sbjct: 186 SRARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSYVSKAESTPEIAEQRGERDSQTQAI 245

Query: 179 --RLKVYQGLYCVAIRDFKQAAE-LFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPD 235
             +LK   GL  +A R +KQAA+ L L +       EL+       Y    ++   +R +
Sbjct: 246 LTKLKCAAGLAELAARKYKQAAKCLLLASFDHCDFPELLSPSNVAIYGGLCALATFDRQE 305

Query: 236 LREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAPHYRYY 295
           L+  VI  +     L   P VR  +F  YE +Y+   + L  ++  +  D   APH R  
Sbjct: 306 LQRNVISSSSFKLFLELEPQVRDIIFKFYESKYASCLKMLDEMKDNLLLDMYLAPHVRTL 365

Query: 296 VREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVE 355
             ++R  A  Q    Y S  +  MA AF   V  ++ EL++ I  G +  ++D  ++I+ 
Sbjct: 366 YTQIRNRALIQYFSPYVSADMHRMAAAFNTTVAALEDELTQLILEGLISARVDSHSKILY 425

Query: 356 TNRPDSKNWQYQETIKKGDLLLNRVQKL 383
               D ++  +++++  G     R + +
Sbjct: 426 ARDVDQRSTTFEKSLLMGKEFQRRAKAM 453


>gi|38044112 restin isoform b [Homo sapiens]
          Length = 1392

 Score = 34.3 bits (77), Expect = 0.20
 Identities = 23/84 (27%), Positives = 44/84 (52%), Gaps = 2/84 (2%)

Query: 65  IDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEI-RDAMMAKAEYLCR-IGDKEGALT 122
           +D+D L K     + E+K+L ++LE AEK +   EI ++A  +KA  + R +  +E  LT
Sbjct: 728 LDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLT 787

Query: 123 AFRKTYDKTVALGHRLDIVFYLLR 146
             ++   +   +   L+    +L+
Sbjct: 788 NLQENLSEVSQVKETLEKELQILK 811


>gi|4506751 restin isoform a [Homo sapiens]
          Length = 1427

 Score = 34.3 bits (77), Expect = 0.20
 Identities = 23/84 (27%), Positives = 44/84 (52%), Gaps = 2/84 (2%)

Query: 65  IDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEI-RDAMMAKAEYLCR-IGDKEGALT 122
           +D+D L K     + E+K+L ++LE AEK +   EI ++A  +KA  + R +  +E  LT
Sbjct: 763 LDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLT 822

Query: 123 AFRKTYDKTVALGHRLDIVFYLLR 146
             ++   +   +   L+    +L+
Sbjct: 823 NLQENLSEVSQVKETLEKELQILK 846


>gi|70995235 AMMECR1 protein isoform 2 [Homo sapiens]
          Length = 296

 Score = 33.9 bits (76), Expect = 0.26
 Identities = 29/107 (27%), Positives = 48/107 (44%), Gaps = 9/107 (8%)

Query: 27  SLPEHRGDAAVRDELMAAVRDNNMAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDE 86
           +L + R     RDEL       ++   +E +C  LDW++ V  + +++  NE   KR   
Sbjct: 159 ALKDSRFPPMTRDELPRLFCSVSLLTNFEDVCDYLDWEVGVHGI-RIEFINEKGSKRTAT 217

Query: 87  ELEDAEKNLGESEIR--DAMMAKAEYLCRIGDKEGALTAFRKTYDKT 131
            L +  K  G   I+  D+++ K  Y   I ++      FRKT   T
Sbjct: 218 YLPEVAKEQGWDHIQTIDSLLRKGGYKAPITNE------FRKTIKLT 258


>gi|7669554 AMMECR1 protein isoform 1 [Homo sapiens]
          Length = 333

 Score = 33.9 bits (76), Expect = 0.26
 Identities = 29/107 (27%), Positives = 48/107 (44%), Gaps = 9/107 (8%)

Query: 27  SLPEHRGDAAVRDELMAAVRDNNMAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDE 86
           +L + R     RDEL       ++   +E +C  LDW++ V  + +++  NE   KR   
Sbjct: 196 ALKDSRFPPMTRDELPRLFCSVSLLTNFEDVCDYLDWEVGVHGI-RIEFINEKGSKRTAT 254

Query: 87  ELEDAEKNLGESEIR--DAMMAKAEYLCRIGDKEGALTAFRKTYDKT 131
            L +  K  G   I+  D+++ K  Y   I ++      FRKT   T
Sbjct: 255 YLPEVAKEQGWDHIQTIDSLLRKGGYKAPITNE------FRKTIKLT 295


>gi|219842262 COP9 constitutive photomorphogenic homolog subunit 2
           isoform 2 [Homo sapiens]
          Length = 450

 Score = 33.5 bits (75), Expect = 0.34
 Identities = 17/85 (20%), Positives = 40/85 (47%)

Query: 271 FFQSLAVVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFI 330
           F + L      +  D     H    +R +R     +L++ Y  + + ++++   + V  +
Sbjct: 333 FEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADV 392

Query: 331 DQELSRFIAAGRLHCKIDKVNEIVE 355
           +  L + I    +H +ID+VN+++E
Sbjct: 393 ESLLVQCILDNTIHGRIDQVNQLLE 417


>gi|4759264 COP9 constitutive photomorphogenic homolog subunit 2
           isoform 1 [Homo sapiens]
          Length = 443

 Score = 33.5 bits (75), Expect = 0.34
 Identities = 17/85 (20%), Positives = 40/85 (47%)

Query: 271 FFQSLAVVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFI 330
           F + L      +  D     H    +R +R     +L++ Y  + + ++++   + V  +
Sbjct: 326 FEKILKTNHSNIMDDPFIREHIEELLRNIRTQVLIKLIKPYTRIHIPFISKELNIDVADV 385

Query: 331 DQELSRFIAAGRLHCKIDKVNEIVE 355
           +  L + I    +H +ID+VN+++E
Sbjct: 386 ESLLVQCILDNTIHGRIDQVNQLLE 410


>gi|4506221 proteasome 26S non-ATPase subunit 12 isoform 1 [Homo
           sapiens]
          Length = 456

 Score = 32.3 bits (72), Expect = 0.75
 Identities = 19/86 (22%), Positives = 40/86 (46%)

Query: 302 HAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDS 361
           H    + + Y  +T+  MA+   + V+  +  LS  +    +  K+D++  I+   RP  
Sbjct: 361 HNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKD 420

Query: 362 KNWQYQETIKKGDLLLNRVQKLSRVI 387
            N    +  +K + L++ V K + +I
Sbjct: 421 PNNLLNDWSQKLNSLMSLVNKTTHLI 446


>gi|28872765 proteasome 26S non-ATPase subunit 12 isoform 2 [Homo
           sapiens]
          Length = 436

 Score = 32.3 bits (72), Expect = 0.75
 Identities = 19/86 (22%), Positives = 40/86 (46%)

Query: 302 HAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDS 361
           H    + + Y  +T+  MA+   + V+  +  LS  +    +  K+D++  I+   RP  
Sbjct: 341 HNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKD 400

Query: 362 KNWQYQETIKKGDLLLNRVQKLSRVI 387
            N    +  +K + L++ V K + +I
Sbjct: 401 PNNLLNDWSQKLNSLMSLVNKTTHLI 426


>gi|92859701 myosin VI [Homo sapiens]
          Length = 1285

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 5/68 (7%)

Query: 39  DELMAAVRDNNMAPY-----YEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEK 93
           D LMA ++   M        Y+AL KS +  +      K ++   + L+R+ EE+E   K
Sbjct: 879 DTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERK 938

Query: 94  NLGESEIR 101
              E E R
Sbjct: 939 RREEDEKR 946


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
           sapiens]
          Length = 1938

 Score = 30.4 bits (67), Expect = 2.8
 Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 13/94 (13%)

Query: 9   EGLPKNPDLRIAQLRFLLSLPEHRGDAAVRDELMAAVRDNNMAPYYEALCKSL-----DW 63
           EGL K+  L  A+++ L    E   +  +  EL+A  R+       E  C SL     D 
Sbjct: 910 EGLIKSKILLEAKVKELTERLEEEEE--MNSELVAKKRN------LEDKCSSLKRDIDDL 961

Query: 64  QIDVDLLNKMKKANEDELKRLDEELEDAEKNLGE 97
           ++ +  + K K A E+++K L EE+   E+N+ +
Sbjct: 962 ELTLTKVEKEKHATENKVKNLSEEMTALEENISK 995


>gi|7657138 golgi integral membrane protein 4 [Homo sapiens]
          Length = 696

 Score = 30.4 bits (67), Expect = 2.8
 Identities = 17/61 (27%), Positives = 33/61 (54%)

Query: 67  VDLLNKMKKANEDELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCRIGDKEGALTAFRK 126
           +++ ++M K+  +ELK+   +LE+  +  GE   R     K +YL    +KE  L+  ++
Sbjct: 114 LNVQHQMLKSQHEELKKQHSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKE 173

Query: 127 T 127
           T
Sbjct: 174 T 174


>gi|226495417 coiled-coil domain containing 102A [Homo sapiens]
          Length = 550

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 21/54 (38%), Positives = 31/54 (57%), Gaps = 5/54 (9%)

Query: 54  YEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIRDAMMAK 107
           YE L K+   Q  +  L+ +K+A++DEL R+ E+LED    LG     D  MA+
Sbjct: 294 YEELSKTK--QEMLKQLSILKEAHQDELGRMSEDLED---ELGARSSMDRKMAE 342


>gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]
          Length = 1191

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 26/76 (34%), Positives = 34/76 (44%), Gaps = 16/76 (21%)

Query: 54  YEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKN---LGESEIRDAMMAKA-- 108
           YE +CK         LL   K A +D  K+L E  E  EK+   LG + + D +  KA  
Sbjct: 621 YEGICK---------LLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAAD 671

Query: 109 --EYLCRIGDKEGALT 122
             E L + G K   LT
Sbjct: 672 TIEALQKAGIKVWVLT 687


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
            sapiens]
          Length = 1983

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 8/70 (11%)

Query: 69   LLNKMKKANEDELKRLDEELEDAEKNLGESE------IRDAMMAKAEYLCRIGDKEGALT 122
            LLN+ KK   D L +L  E+E+A +   E+E      I DA M  AE L +  D    L 
Sbjct: 1772 LLNQKKKLEAD-LAQLSGEVEEAAQERREAEEKAKKAITDAAM-MAEELKKEQDTSAHLE 1829

Query: 123  AFRKTYDKTV 132
              +KT ++TV
Sbjct: 1830 RMKKTLEQTV 1839


>gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]
          Length = 1134

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 26/76 (34%), Positives = 34/76 (44%), Gaps = 16/76 (21%)

Query: 54  YEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKN---LGESEIRDAMMAKA-- 108
           YE +CK         LL   K A +D  K+L E  E  EK+   LG + + D +  KA  
Sbjct: 621 YEGICK---------LLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAAD 671

Query: 109 --EYLCRIGDKEGALT 122
             E L + G K   LT
Sbjct: 672 TIEALQKAGIKVWVLT 687


>gi|13899233 tetratricopeptide repeat domain 25 [Homo sapiens]
          Length = 672

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 7/129 (5%)

Query: 80  ELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCRIGDKEGALTAFRK---TYDKTVALGH 136
           EL +++  L+   K+L  ++  D   AK+  L  IG     +  F++   T+++ + L  
Sbjct: 332 ELGQMEAALQSHRKDLEIAKEYDLPDAKSRALDNIGRVFARVGKFQQAIDTWEEKIPLAK 391

Query: 137 R-LDIVFYLLRIGLFYMDNDLITRNT---EKAKSLIEEGGDWDRRNRLKVYQGLYCVAIR 192
             L+  +    IG  Y++ D   +     EK++   EE GD + +    V      V +R
Sbjct: 392 TTLEKTWLFHEIGRCYLELDQAWQAQNYGEKSQQCAEEEGDIEWQLNASVLVAQAQVKLR 451

Query: 193 DFKQAAELF 201
           DF+ A   F
Sbjct: 452 DFESAVNNF 460


>gi|82659109 retinoblastoma-associated factor 600 [Homo sapiens]
          Length = 5183

 Score = 30.0 bits (66), Expect = 3.7
 Identities = 27/118 (22%), Positives = 52/118 (44%), Gaps = 10/118 (8%)

Query: 250  LHSLPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLE 309
            LH +P+++    S+Y    ++    +++ E   K      PH    + +  + A  QL++
Sbjct: 1112 LHEIPSLQ----SIYTLDAAISKVQVSLDEHFSKMAAETDPHKSSEITKNLLPATLQLID 1167

Query: 310  SYRSLTLGYMAEAF---GVGVEFIDQELSRF---IAAGRLHCKIDKVNEIVETNRPDS 361
            +Y S T  Y+ + F   G   +   ++L  F   +A G   CK + +   +  N P S
Sbjct: 1168 TYASFTRAYLLQNFNEEGTTEKPSKEKLQGFAAVLAIGSSRCKANTLGPTLVQNLPSS 1225


>gi|4502175 apical protein of Xenopus-like [Homo sapiens]
          Length = 1616

 Score = 29.6 bits (65), Expect = 4.9
 Identities = 55/250 (22%), Positives = 97/250 (38%), Gaps = 31/250 (12%)

Query: 23   RFLLSLPEHRGDAAVRDE--LMAAVRDNNMAPYYEALCKSLDWQIDVDLLNKMKKANEDE 80
            + L  +P  R     ++E  + AAV     + YY       +  I +  L + ++  ED 
Sbjct: 1366 KLLPKIPSPRSTEERKEEPSVPAAVSLATNSTYYSTSAPKAELLIKMKDLQEQQEHEEDS 1425

Query: 81   LKRLDEELEDAEKNLGES---------EIRDAMMAKAEYLCRIGDKEGAL---TAFRKTY 128
               LD +L   ++ L ES         E R++++   +    +G +  A+         +
Sbjct: 1426 GSDLDHDLSVKKQELIESISRKLQVLREARESLLEDVQANTVLGAEVEAIVKGVCKPSEF 1485

Query: 129  DKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYC 188
            DK       LD V  LL      +         E A + +++G     R  L   Q +  
Sbjct: 1486 DKFRMFIGDLDKVVNLL------LSLSGRLARVENALNNLDDGASPGDRQSLLEKQRVLI 1539

Query: 189  VAIRDFKQAAE-------LFLDTVSTFTSYE-LMDYKTFVTYTVYVSMIALERPDLREKV 240
                D K+  E       +  D ++ + S E L DY+ FV      S + +E+ +L +K+
Sbjct: 1540 QQHEDAKELKENLDRRERIVFDILANYLSEESLADYEHFVKMK---SALIIEQRELEDKI 1596

Query: 241  IKGAEILEVL 250
              G E L+ L
Sbjct: 1597 HLGEEQLKCL 1606


>gi|6857820 phosphatidylinositol-5-phosphate 4-kinase, type II,
           alpha [Homo sapiens]
          Length = 406

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 16/72 (22%), Positives = 35/72 (48%)

Query: 28  LPEHRGDAAVRDELMAAVRDNNMAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDEE 87
           LP  + +  + +     + DNN   + E L K +++   + L++        +++R ++E
Sbjct: 230 LPTLKDNDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQE 289

Query: 88  LEDAEKNLGESE 99
             + E+N GE E
Sbjct: 290 EVECEENDGEEE 301


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 6/57 (10%)

Query: 241 IKGAEI-LEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAP--HYRY 294
           I GA I   +L    A+RQ   +  EC + +F+Q L    +++K D L  P  HYR+
Sbjct: 284 IVGANIETYLLEKSRAIRQ---AKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRF 337


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 6/57 (10%)

Query: 241 IKGAEI-LEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAP--HYRY 294
           I GA I   +L    A+RQ   +  EC + +F+Q L    +++K D L  P  HYR+
Sbjct: 276 IVGANIETYLLEKSRAIRQ---AKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRF 329


>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 6/57 (10%)

Query: 241 IKGAEI-LEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAP--HYRY 294
           I GA I   +L    A+RQ   +  EC + +F+Q L    +++K D L  P  HYR+
Sbjct: 284 IVGANIETYLLEKSRAIRQ---AKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRF 337


>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
            [Homo sapiens]
          Length = 8749

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 22/66 (33%), Positives = 37/66 (56%), Gaps = 4/66 (6%)

Query: 67   VDLLNKMKKANEDEL--KRLDEELEDAEKNLGESEIRDAMMAKAEYLCRIGDKEGALTAF 124
            V+  N M K NE +L  K L++ L++A+     +   D +++KA+Y  +IG  E   T+ 
Sbjct: 1898 VEATNSMNK-NESDLIEKDLNDALQNAKALESAAVSLDGILSKAQYHLKIGSSE-QRTSC 1955

Query: 125  RKTYDK 130
            R T D+
Sbjct: 1956 RATADQ 1961


>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
            [Homo sapiens]
          Length = 8797

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 22/66 (33%), Positives = 37/66 (56%), Gaps = 4/66 (6%)

Query: 67   VDLLNKMKKANEDEL--KRLDEELEDAEKNLGESEIRDAMMAKAEYLCRIGDKEGALTAF 124
            V+  N M K NE +L  K L++ L++A+     +   D +++KA+Y  +IG  E   T+ 
Sbjct: 1891 VEATNSMNK-NESDLIEKDLNDALQNAKALESAAVSLDGILSKAQYHLKIGSSE-QRTSC 1948

Query: 125  RKTYDK 130
            R T D+
Sbjct: 1949 RATADQ 1954


>gi|31982906 cingulin-like 1 [Homo sapiens]
          Length = 1302

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 2/89 (2%)

Query: 1   MPLENLEEEGLPKNPDLRIAQLRFLLSLPEHRGDAAVRDELMAAVRDNNMAPY--YEALC 58
           +P EN EE  LP+NP  + + +R L     H G   V D    +V+ +++  +  +  L 
Sbjct: 93  VPKENSEELQLPENPYAQPSPIRNLKQPLLHEGKNGVLDRKDGSVKPSHLLNFQRHPELL 152

Query: 59  KSLDWQIDVDLLNKMKKANEDELKRLDEE 87
           +  D + +   L   + +  + LK L EE
Sbjct: 153 QPYDPEKNELNLQNHQPSESNWLKTLTEE 181


>gi|55769583 progesterone-induced blocking factor 1 [Homo sapiens]
          Length = 757

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 16/55 (29%), Positives = 30/55 (54%), Gaps = 3/55 (5%)

Query: 52  PYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIRDAMMA 106
           P  + +C   + Q+  ++L +    N+++LK+L E  E+  KN  E +IR   +A
Sbjct: 193 PLRKEIC---ELQVKKNILAEELSTNKNQLKQLTETYEEDRKNYSEVQIRCQRLA 244


>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
          Length = 284

 Score = 28.9 bits (63), Expect = 8.3
 Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 2/45 (4%)

Query: 55 EALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESE 99
          E  CK ++ ++    L K  K  EDEL +  E+L+DA++ L  +E
Sbjct: 33 EDKCKQVEEELTH--LQKKLKGTEDELDKYSEDLKDAQEKLELTE 75


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,996,560
Number of Sequences: 37866
Number of extensions: 525158
Number of successful extensions: 2078
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 2015
Number of HSP's gapped (non-prelim): 95
length of query: 389
length of database: 18,247,518
effective HSP length: 104
effective length of query: 285
effective length of database: 14,309,454
effective search space: 4078194390
effective search space used: 4078194390
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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