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Search of human proteins with 7657387
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo
sapiens]
(753 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens] 1532 0.0
gi|163965366 nascent polypeptide-associated complex alpha subuni... 87 6e-17
gi|55750053 atrophin-1 [Homo sapiens] 81 3e-15
gi|55750041 atrophin-1 [Homo sapiens] 81 3e-15
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 78 3e-14
gi|18375613 dachshund homolog 1 isoform b [Homo sapiens] 77 5e-14
gi|18375611 dachshund homolog 1 isoform a [Homo sapiens] 77 5e-14
gi|18375609 dachshund homolog 1 isoform c [Homo sapiens] 77 5e-14
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 77 6e-14
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 77 6e-14
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 77 6e-14
gi|110832843 TBP-associated factor 4 [Homo sapiens] 75 2e-13
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 75 2e-13
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 75 2e-13
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 74 7e-13
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 71 3e-12
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 71 3e-12
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 71 4e-12
gi|47132519 Ras association and pleckstrin homology domains 1 is... 70 7e-12
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 70 7e-12
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 70 7e-12
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 70 7e-12
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 70 9e-12
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 70 9e-12
gi|119395716 forkhead box C1 [Homo sapiens] 69 2e-11
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 68 3e-11
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 68 3e-11
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 68 3e-11
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 68 3e-11
gi|28559039 mediator complex subunit 1 [Homo sapiens] 68 3e-11
>gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]
Length = 753
Score = 1532 bits (3966), Expect = 0.0
Identities = 753/753 (100%), Positives = 753/753 (100%)
Query: 1 MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRD 60
MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRD
Sbjct: 1 MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRD 60
Query: 61 QIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKE 120
QIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKE
Sbjct: 61 QIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKE 120
Query: 121 KEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDKQDRIEGLKRHIEKHRYHV 180
KEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDKQDRIEGLKRHIEKHRYHV
Sbjct: 121 KEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDKQDRIEGLKRHIEKHRYHV 180
Query: 181 RMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVA 240
RMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVA
Sbjct: 181 RMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVA 240
Query: 241 TSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSP 300
TSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSP
Sbjct: 241 TSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSP 300
Query: 301 AKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPA 360
AKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPA
Sbjct: 301 AKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPA 360
Query: 361 PSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGA 420
PSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGA
Sbjct: 361 PSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGA 420
Query: 421 GKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGA 480
GKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGA
Sbjct: 421 GKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGA 480
Query: 481 GGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPL 540
GGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPL
Sbjct: 481 GGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPL 540
Query: 541 SSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVC 600
SSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVC
Sbjct: 541 SSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVC 600
Query: 601 PLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDTV 660
PLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDTV
Sbjct: 601 PLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDTV 660
Query: 661 EFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEFE 720
EFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEFE
Sbjct: 661 EFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEFE 720
Query: 721 QGTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ 753
QGTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ
Sbjct: 721 QGTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ 753
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 87.0 bits (214), Expect = 6e-17
Identities = 109/450 (24%), Positives = 160/450 (35%), Gaps = 73/450 (16%)
Query: 261 PTSTTSSSPIP------PSPANC-TTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQH 313
PT+ ++ P P PSP TT + +G +P + P
Sbjct: 1195 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1254
Query: 314 PQSPAVP--PTYPSGPPPAASALSTTPGNNGVPAPAA--PPSALGPKAS----------- 358
P +P PT P+ PP+ TP + G P PA PPS G A+
Sbjct: 1255 PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPA 1314
Query: 359 ---PAPSHNSGTP----APYAQAVAPPAPSG----PSTTQ--------------PRPPSV 393
P+P + GTP AP AV PP+P G P+TT P PP+
Sbjct: 1315 ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAA 1374
Query: 394 QPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQ 453
PS GG + + + G G + +V+ SP + + A++
Sbjct: 1375 TPS------HKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATP 1428
Query: 454 ALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFS 513
+ G + P P S K P+ +AP G P + ++ G P+L P +P P P
Sbjct: 1429 SKGDLTPPAVTPVSLKKAPATSAPKGG----PATPSSKGDPTLPAVTPPSPKEPPAPKQV 1484
Query: 514 DAKAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPV-PTLHLTERDIIL 572
++ P AP + A P S E A S DP+ PT L +
Sbjct: 1485 ATSSSPKKAPATPAPMGAPTLPAVIP----SSPKEVPATPSSRRDPIAPTATLLSKK--T 1538
Query: 573 SSTSAPPASAQPPLQL--SEVNIPLSLGVCPLGPVPLTKEQLYQQAMEEAAWHHMPHPSD 630
+T AP + PP S P P +KE A+ + + P P +
Sbjct: 1539 PATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKE 1598
Query: 631 -------SERIRQYLPRNPCPTPPYHHQMP 653
+ + P P TPP + P
Sbjct: 1599 LLIPPAVTSPSPKEAPTPPAVTPPSPEKGP 1628
Score = 85.9 bits (211), Expect = 1e-16
Identities = 109/432 (25%), Positives = 158/432 (36%), Gaps = 42/432 (9%)
Query: 244 PSHSHMEDEIFNQSSSTPTSTTSSSP----IPPSPANCTTENSEDDKKRGRSTDSEVSQS 299
P+ +H + + TP++ T SP +PP + + K G +T + Q+
Sbjct: 850 PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAP-KQA 908
Query: 300 PAKN--GSKPVHSNQHPQSPAVP--------PTYPSGPPPAASALSTTPGNNGVPAP--A 347
PA + S P + P +P PT P+ PP+ TP P P A
Sbjct: 909 PALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAA 968
Query: 348 APPSALGPKASPAPSHNSGTPAPYAQAVAPPAPSG-PSTTQPR----PPSVQPSGGGGGG 402
PPS G A+P+P G P P A PP+P G P+T P+ PP+V P G
Sbjct: 969 TPPSPKGGPATPSPK---GAPTP--PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSP 1023
Query: 403 SGGGGSSSSSNSSAGGGAGKQNG--ATSYSSVVADSPAEVALSSSGGNNASSQALGPPSG 460
+ +S A + AT +PA S GG A+ G P+
Sbjct: 1024 AATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGP-ATPSLKGAPTP 1082
Query: 461 PHNPPPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGA 520
P PPS P+ +P GA + P + S L P P+ TP+ + G
Sbjct: 1083 PAATPPSPKGGPATPSPKGA-PMPPAATPPSPKGGLATPPHKGAPT--TPAATPPSPKGG 1139
Query: 521 LLNGPPQFS-TAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPP 579
L PP+ + T P P P L + + A ++ P T + + S P
Sbjct: 1140 LATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTT----PAATPPSPKGGLATPSPKGAP 1195
Query: 580 A--SAQPPLQLSEVNIPLSLG--VCPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIR 635
+A PP + P G P P K L + + A P +
Sbjct: 1196 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGP 1255
Query: 636 QYLPRNPCPTPP 647
P PTPP
Sbjct: 1256 ATPPPKGAPTPP 1267
Score = 83.6 bits (205), Expect = 6e-16
Identities = 111/428 (25%), Positives = 149/428 (34%), Gaps = 74/428 (17%)
Query: 240 ATSPPSHSHMEDEI-FNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQ 298
A +PPS F + +STP + T PPSP +G T +
Sbjct: 1013 AVTPPSPKGSPAATPFPKGASTPPAAT-----PPSPKGSPAATP---LPKGAPTTPAATL 1064
Query: 299 SPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAP--AAPPSALGPK 356
K G P PA P P G P TP G P P A PPS G
Sbjct: 1065 PSPKGGPATPSLKGAPTPPAATPPSPKGGP-------ATPSPKGAPMPPAATPPSPKGGL 1117
Query: 357 ASP----APSHNSGTP--------------APYAQAVAPPAPSGPSTTQP------RPPS 392
A+P AP+ + TP AP A PP+P G T P P +
Sbjct: 1118 ATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1177
Query: 393 VQPSGGGG----GGSGGGGSSSSSNSSAGGGAG--KQNGATSYSSVVADSPAEVALSSSG 446
PS GG G + +++ S GG GA + + SP + S
Sbjct: 1178 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP 1237
Query: 447 GNNASSQALGPPS---GPHNPPPSTSKEPSAAAPTG-AGGVAPGSGNNSGGPSLLVPLPV 502
++ A PPS GP PPP + P AA P GG+A + + G P+ V P
Sbjct: 1238 KGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLA--TPPHKGAPNPAVVTPP 1295
Query: 503 NPPSSPT----------PSFSDAKAAGALLNGPPQFS-TAPEIKAPEPLSSLKSMAERAA 551
+P P P+ + G+ PP+ + T P + P P + A +
Sbjct: 1296 SPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355
Query: 552 ISSGIEDPV----PTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVCPLGP--- 604
G P PT PP+ + P S P S V PL P
Sbjct: 1356 SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA 1415
Query: 605 --VPLTKE 610
P+T+E
Sbjct: 1416 PATPVTRE 1423
Score = 78.2 bits (191), Expect = 3e-14
Identities = 86/317 (27%), Positives = 116/317 (36%), Gaps = 24/317 (7%)
Query: 231 LEDIPQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGR 290
L D P L + P + + TP SS P+ P A+ ENS +
Sbjct: 790 LADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSS-PVSPVEASFLPENSLSFQGSKD 848
Query: 291 STDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPP 350
S + S +P P S P SP P P TP +P P P
Sbjct: 849 SPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETP--------TPSVVNLPFPKEGP 900
Query: 351 SALGPKASPAPSHNSGTPAPYAQAVAPPAPSG-PSTTQPR----PPSVQPSGGGGGGSGG 405
+ PK +PA S S +P +A A PAP G P++ P+ PP+ P GG +
Sbjct: 901 ATPAPKQAPALSMTSSSPK---KARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATP 957
Query: 406 GGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPP 465
+ + +A + K AT PA S GG A+ G P+ P P
Sbjct: 958 SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGP-ATPSPKGAPTPPAVTP 1016
Query: 466 PSTSKEPSAAA-PTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGAL--L 522
PS P+A P GA + + G PLP P++P + K A L
Sbjct: 1017 PSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSL 1076
Query: 523 NGPPQFSTAPEIKAPEP 539
G P T P P P
Sbjct: 1077 KGAP---TPPAATPPSP 1090
Score = 77.0 bits (188), Expect = 6e-14
Identities = 99/387 (25%), Positives = 136/387 (35%), Gaps = 36/387 (9%)
Query: 235 PQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDS 294
P+ +AT PP + +++ P+ + PP A T + K G +T S
Sbjct: 1136 PKGGLATPPPKGAPT-----TPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPS 1190
Query: 295 E--VSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPA-PAAPPS 351
+PA P P SP PT P+ PP+ TP G P PAA P
Sbjct: 1191 PKGAPTTPAATPPSPKGGLATP-SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1249
Query: 352 ALGPKASPAPSHNSGTPAPYAQAVAPPAPSG-----PSTTQPRPPSVQPSGGGGGGSGGG 406
+ PK PA G P P A PP+ G P P P V P GG +
Sbjct: 1250 S--PKGGPATPPPKGAPTP--PAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP 1305
Query: 407 GSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPP 466
+ + +A + K + T PA S G + GP P
Sbjct: 1306 PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSS 1365
Query: 467 STSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTP---SFSDAKAAGALLN 523
P AA P+ GG A + GP+ +P P P+SP S A A
Sbjct: 1366 KEGPTPPAATPSHKGGPAMTPPSPKRGPA--IPSPKGDPTSPAVIPLSPKKAPATPVTRE 1423
Query: 524 G---PPQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPA 580
G P + P P SLK +A G P ++ D L + + PP+
Sbjct: 1424 GAATPSKGDLTPPAVTP---VSLKKAPATSAPKGG-----PATPSSKGDPTLPAVT-PPS 1474
Query: 581 SAQPPLQLSEVNIPLSLGVCPLGPVPL 607
+PP +V S P P P+
Sbjct: 1475 PKEPPAP-KQVATSSSPKKAPATPAPM 1500
Score = 67.0 bits (162), Expect = 6e-11
Identities = 101/403 (25%), Positives = 141/403 (34%), Gaps = 37/403 (9%)
Query: 235 PQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDS 294
P+ AT P + + S +T SS P +P T K
Sbjct: 1490 PKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAP----TATLLSKKTPATLAPK 1545
Query: 295 EVSQSPAKNGSKPVHSNQHP---QSPAVPPTYPSGPPPAASALSTTPGN-NGVPAPAA-- 348
E PA P + P ++PA P + + PPA TP G P+P
Sbjct: 1546 EALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV-----TPSTYKGAPSPKELL 1600
Query: 349 -PPSALGPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGG 407
PP+ P AP+ + TP + A PAP G T+ P PS S
Sbjct: 1601 IPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCK 1660
Query: 408 SSSSSNSSAGGGAGKQNGATSYSSVVADSPAE----VALSSSGGNNASSQALGPPSGPHN 463
++ ++ G K+ +VA +P A + G S A PP P
Sbjct: 1661 MGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDP 1720
Query: 464 PPPSTSKEP-SAAAPTGAGGVAPGSGNNSGG--PSLLVPLPVNPPSSPTPSFSDAKAAGA 520
+ SK P S AP V S + G S P+ PP S + A A
Sbjct: 1721 SAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEK 1780
Query: 521 LLNGPPQFST----APEIK---APEPLSSLKSMAERAAISSG--IEDPVPTLHLTERDII 571
+L P S +P + AP P+ +L + S G +E P L + D +
Sbjct: 1781 VLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDEL 1840
Query: 572 LSSTSAPPASAQPPLQLSEVNIPL--SLGV---CPLGPVPLTK 609
L P S P Q VN+P S G+ P P+TK
Sbjct: 1841 LPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTK 1883
Score = 55.8 bits (133), Expect = 1e-07
Identities = 76/323 (23%), Positives = 121/323 (37%), Gaps = 42/323 (13%)
Query: 291 STDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTP---GNNGVPAPA 347
+T+ E+ Q A+ P+ S+ + A+ P+ PPP + A P N P P+
Sbjct: 11 ATEQELPQPQAETAVLPM-SSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPS 69
Query: 348 APPSALGPKASPAPSHNSGTPAPYAQAVAPPA--------PSGPSTTQPRPPSVQPSGGG 399
A P P P +SGT P A P P P+ P + P+
Sbjct: 70 PSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPT--- 126
Query: 400 GGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPS 459
G SSS+ + ++++ + SP VA++ SG S L P
Sbjct: 127 ---LKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESG----SVITLSAPI 179
Query: 460 GPHNPPPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAG 519
P P + +K PS P G +P P ++ +P + TP S
Sbjct: 180 APSEPKTNLNKVPSEVVPNPKGTPSP--------PCIVSTVPYH---CVTPMASIQSGVA 228
Query: 520 ALLNGPPQFSTA---PEIKAPEPLSSLKSMAERAAIS-SGIEDPVPTLHLTERDIILSST 575
+L P + A P++K S L S ++S G P L L+ + + + ++
Sbjct: 229 SLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTS 288
Query: 576 SAPPASAQPPLQLSEVNIPLSLG 598
S A P + P+SLG
Sbjct: 289 SQKTAGPNTP-----PDFPISLG 306
Score = 41.6 bits (96), Expect = 0.003
Identities = 85/406 (20%), Positives = 133/406 (32%), Gaps = 57/406 (14%)
Query: 225 LYDDLDLEDIPQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSED 284
L D DL+++P +++ P + T ++ +P P+ A TT+
Sbjct: 509 LPDPEDLKNLPSSVLVKFPTQ----------KDLQTVPASLEGAPFSPAQAGLTTKKDP- 557
Query: 285 DKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPT----------YPSGPPPAASAL 334
T + Q+ KN ++ P+ P P P G P AS++
Sbjct: 558 -------TVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKP--ASSM 608
Query: 335 STTPGNNGVPAPAAPPSALGP-KASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSV 393
++ G N + S GP A P + TP A + P+G + T + S
Sbjct: 609 TSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTST 668
Query: 394 QPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQ 453
+ G + S A + G + +V + ++ S N +
Sbjct: 669 YTTTASPFLEG-------TVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPL 721
Query: 454 A---LGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTP 510
A L P P PS P A P G V + S L P+ +P PT
Sbjct: 722 ATLVLAPEIPKSVPSPSL---PPAGTPPGTKKV-----DGISHTSALAPVASSPKECPTE 773
Query: 511 ---SFSDAKAAGALLN-----GPPQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPVPT 562
+ + A + G L P S +P+ K P S PV
Sbjct: 774 DSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEA 833
Query: 563 LHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVCPLGPVPLT 608
L E + + PA+ P S P V PL P +T
Sbjct: 834 SFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVT 879
Score = 36.6 bits (83), Expect = 0.088
Identities = 96/427 (22%), Positives = 133/427 (31%), Gaps = 95/427 (22%)
Query: 239 VATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQ 298
V T HS +Q S P + + +P + A DK G ST S ++
Sbjct: 336 VKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDK--GPSTISSITC 393
Query: 299 SPAKN-------GSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTP--GNNGVPAPAAP 349
SP+ + P S SP YP S++ TTP N AAP
Sbjct: 394 SPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAP 453
Query: 350 PSA------LGPKASPAPSHNSGTPAPYAQAVAPPAPSGPST---TQPRPPSVQPSGGGG 400
+ + P S P N +P A +AP AP PST T R P P
Sbjct: 454 TTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPL---- 509
Query: 401 GGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSG 460
++ SSV+ P + L + + G P
Sbjct: 510 -------------------PDPEDLKNLPSSVLVKFPTQKDLQT-----VPASLEGAPFS 545
Query: 461 PHNPPPSTSKEPSA-----AAPTGAGGVAPGSGNNSGGP-------------SLLVPLPV 502
P +T K+P+ AAP +P + S P SL PLP+
Sbjct: 546 PAQAGLTTKKDPTVLPLVQAAPKN----SPSFQSTSSSPEIPLSPEATLAKKSLGEPLPI 601
Query: 503 NPPSS---------------PTPSFSDAKAAGALLNGP---------PQFSTAPEIKAPE 538
P+S T S++ +AG LL P S P AP
Sbjct: 602 GKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPT 661
Query: 539 PLSSLKSMAERAA-ISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSL 597
+ A+ G P H + + + P AS P+ S N L
Sbjct: 662 TAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPL 721
Query: 598 GVCPLGP 604
L P
Sbjct: 722 ATLVLAP 728
Score = 35.0 bits (79), Expect = 0.26
Identities = 49/200 (24%), Positives = 64/200 (32%), Gaps = 40/200 (20%)
Query: 240 ATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQS 299
ATSPP D S P ST + +P+ P +D K + D+ S
Sbjct: 1711 ATSPPI---CPDPSAKNGSKGPLSTVAPAPLLPV--------QKDSSKTAKGKDASHSPK 1759
Query: 300 -----PAKNGSKPV------------HSNQHPQSPAVPPTYPSGP------PPAASALST 336
P S P+ S +P+ P + P P PP L +
Sbjct: 1760 GPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPS 1819
Query: 337 TPG----NNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPS 392
+PG + P A L P P P SG + V P P P P +
Sbjct: 1820 SPGLVLESPSKPLAPADEDELLPLIPPEPI--SGGVPFQSVLVNMPTPKSAGIPVPTPSA 1877
Query: 393 VQPSGGGGGGSGGGGSSSSS 412
QP GSG S S
Sbjct: 1878 KQPVTKNNKGSGTESDSDES 1897
Score = 34.3 bits (77), Expect = 0.44
Identities = 101/444 (22%), Positives = 150/444 (33%), Gaps = 85/444 (19%)
Query: 291 STDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTT---PGNNGVPAP- 346
+T EV+ + S SN P SPA P P ++ ++TT P + +P P
Sbjct: 454 TTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPE 513
Query: 347 --------------------AAPPSALGPKASPA----PSHNSGTPAPYAQAVAPPAPSG 382
P S G SPA + T P QA +PS
Sbjct: 514 DLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSF 573
Query: 383 PSTTQPRPPSVQPSGGGGGGSGG----------------GGSSSSSNSSAGGGAGKQN-G 425
ST+ + P S G G +SS+S AG + G
Sbjct: 574 QSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAG 633
Query: 426 ATSYSSVVADS----------PAEVALSSSGGNNASSQALGP------PSGPHNPPPSTS 469
SS++ + PA VA +++ G + + P P N P
Sbjct: 634 PLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEG 693
Query: 470 KEPS-AAAPTGAGG--VAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGAL--LNG 524
+ PT + VAP N + LV P P S P+PS A ++G
Sbjct: 694 TLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDG 753
Query: 525 PPQFST-APEIKAPEPLSSLKSMAERAAISSG----IEDPVPTLHLTERDIILSSTSAPP 579
S AP +P+ + S A A S G + D L ++ + T PP
Sbjct: 754 ISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVS----VSPQTKRPP 809
Query: 580 ---ASAQPPLQLSEVNIPLSLGVCPLGPVPLTKEQL-YQQAMEEAAWHHMPHPSDSERIR 635
SA P + ++ P+S P+ L + L +Q + + A H P P +
Sbjct: 810 TKKGSAGPDTPIGNLSSPVS----PVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAP 865
Query: 636 QYLPRNPCPTPPYHHQMPPPHSDT 659
P P P +PP + T
Sbjct: 866 --TPSAVTPLSPKGVTLPPKETPT 887
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 81.3 bits (199), Expect = 3e-15
Identities = 134/541 (24%), Positives = 182/541 (33%), Gaps = 123/541 (22%)
Query: 213 SSQDPDFEENEFLYDDLDLEDIPQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPP 272
SS D E++ +E+ V S E E ++ T T P P
Sbjct: 41 SSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQ 100
Query: 273 SPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAV-PPTYPSGPPPAA 331
SP S+ D GRS + + S P + + + SP++ P ++
Sbjct: 101 SP-------SDLDSLDGRSLNDDGSSDP-----RDIDQDNRSTSPSIYSPGSVENDSDSS 148
Query: 332 SALSTTPGNNGVPAPAAPPSALGPKASPAPS------HNSGTPAPYAQAVAPPAP---SG 382
S LS P P P PPS P ++P H S TP Y + PP
Sbjct: 149 SGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQA 208
Query: 383 PSTTQPRPPSVQPSGGGGGGSG------GGGSSSSSNSSAGGGAGKQNG------ATSYS 430
P P P + P G GG SG GGG++SS G GKQ+ + S S
Sbjct: 209 PPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVG---GPNGGKQHPPPTTPISVSSS 265
Query: 431 SVVADSPAEVALSSSGGNNASSQALGPPSGPH---NPPPSTSKEP---SAAAPTGAGGVA 484
P + + GG N S A P + PH N PP + P ++A+P G G
Sbjct: 266 GASGAPPTKPPTTPVGGGNLPS-APPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQP 324
Query: 485 -PGS-------GNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKA 536
PG G GG LP P PT + S A + P AP ++
Sbjct: 325 LPGHLPSPHAMGQGMGG------LPPGPEKGPTLAPSPHSLPPASSSAP-----APPMRF 373
Query: 537 PEPLSSLKSMAERAAISSGIED--PVPTL-------HLTERDIILSSTSAPPASAQPPLQ 587
P SS S A ++ SS P P H LS ++ PP QP L
Sbjct: 374 PYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLP 433
Query: 588 LSEV-----------------------NIPLSLGVCPLGPVPLT-----------KEQLY 613
V P S G P++ ++Q
Sbjct: 434 SQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQ 493
Query: 614 QQAMEEAAWHH----------MPHPSDSERIRQYLPRNPCPT-------PPYHHQMPPPH 656
QQ ++ HH PHP + P P+ PP +PPPH
Sbjct: 494 QQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPH 553
Query: 657 S 657
S
Sbjct: 554 S 554
Score = 63.2 bits (152), Expect = 9e-10
Identities = 109/428 (25%), Positives = 145/428 (33%), Gaps = 98/428 (22%)
Query: 235 PQALVATSPPS---HSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRS 291
P + A +PP +S SSS+ +S++S+SP P S A + +S
Sbjct: 361 PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPP----- 415
Query: 292 TDSEVSQSPAKNGSKPVHSNQ-HPQSPAVPPTY----------PSGPPPAASALSTTP-- 338
T VS P K + S Q P PP Y P PP+ A ST
Sbjct: 416 TSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPP 475
Query: 339 -----------------------------GNNGVPAPAAPPSALGPKASPAPSHNSGTPA 369
GN+G P P A P L SH++
Sbjct: 476 VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPL----EGGSSHHAH--- 528
Query: 370 PYAQAVA----PPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGG------ 419
PYA + + P P GP+ P V S G G SS+SS+S++ G
Sbjct: 529 PYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHP 588
Query: 420 ---AGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAA 476
G Q + V + + LS+ ASS A + P PPP + PS A
Sbjct: 589 SPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGA 648
Query: 477 PTGA--GGVAPGSGNNSGGPSLLVPLP-----VNPPSSP------TPSFSDAKAAGALLN 523
A G PGS PS P +PP+ P +P+ A +
Sbjct: 649 YKTATPPGYKPGS-----PPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPS 703
Query: 524 GPPQFSTAPEIKAP-EPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASA 582
G P P A PLS+ + E A E PVP S S PP
Sbjct: 704 GLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPAR---------SPSPPPKVV 754
Query: 583 QPPLQLSE 590
P S+
Sbjct: 755 DVPSHASQ 762
Score = 55.5 bits (132), Expect = 2e-07
Identities = 71/271 (26%), Positives = 96/271 (35%), Gaps = 49/271 (18%)
Query: 263 STTSSSPIPPSPANCTTENSEDDKKRGRS-----TDSEVSQSPAKNGSKPVHSNQHPQSP 317
S S P PP PA+ +S+ + + S S S GS P Q P
Sbjct: 535 SLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGP 594
Query: 318 AVPPTYPSGPPPAASALSTT------------------------PGNNGVPAPAAPPSAL 353
P YP P P + S T P P+P A +A
Sbjct: 595 QGAP-YPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTAT 653
Query: 354 GPKASPA--PSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSS 411
P P PS +GTP Y + +PPA GP T +P P+V P G +G G S
Sbjct: 654 PPGYKPGSPPSFRTGTPPGY-RGTSPPA--GPGTFKPGSPTVGP--GPLPPAGPSGLPSL 708
Query: 412 SNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKE 471
A +G AT + PAE + ++ PP+ +PPP
Sbjct: 709 PPPPAAPASGPPLSATQ----IKQEPAE--------EYETPESPVPPARSPSPPPKVVDV 756
Query: 472 PSAAAPTGAGGVAPGSGNNSGGPSLLVPLPV 502
PS A+ + G NS S L +P+
Sbjct: 757 PSHASQSARFNKHLDRGFNSCARSDLYFVPL 787
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 81.3 bits (199), Expect = 3e-15
Identities = 134/541 (24%), Positives = 182/541 (33%), Gaps = 123/541 (22%)
Query: 213 SSQDPDFEENEFLYDDLDLEDIPQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPP 272
SS D E++ +E+ V S E E ++ T T P P
Sbjct: 41 SSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQ 100
Query: 273 SPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAV-PPTYPSGPPPAA 331
SP S+ D GRS + + S P + + + SP++ P ++
Sbjct: 101 SP-------SDLDSLDGRSLNDDGSSDP-----RDIDQDNRSTSPSIYSPGSVENDSDSS 148
Query: 332 SALSTTPGNNGVPAPAAPPSALGPKASPAPS------HNSGTPAPYAQAVAPPAP---SG 382
S LS P P P PPS P ++P H S TP Y + PP
Sbjct: 149 SGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQA 208
Query: 383 PSTTQPRPPSVQPSGGGGGGSG------GGGSSSSSNSSAGGGAGKQNG------ATSYS 430
P P P + P G GG SG GGG++SS G GKQ+ + S S
Sbjct: 209 PPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVG---GPNGGKQHPPPTTPISVSSS 265
Query: 431 SVVADSPAEVALSSSGGNNASSQALGPPSGPH---NPPPSTSKEP---SAAAPTGAGGVA 484
P + + GG N S A P + PH N PP + P ++A+P G G
Sbjct: 266 GASGAPPTKPPTTPVGGGNLPS-APPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQP 324
Query: 485 -PGS-------GNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKA 536
PG G GG LP P PT + S A + P AP ++
Sbjct: 325 LPGHLPSPHAMGQGMGG------LPPGPEKGPTLAPSPHSLPPASSSAP-----APPMRF 373
Query: 537 PEPLSSLKSMAERAAISSGIED--PVPTL-------HLTERDIILSSTSAPPASAQPPLQ 587
P SS S A ++ SS P P H LS ++ PP QP L
Sbjct: 374 PYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLP 433
Query: 588 LSEV-----------------------NIPLSLGVCPLGPVPLT-----------KEQLY 613
V P S G P++ ++Q
Sbjct: 434 SQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQ 493
Query: 614 QQAMEEAAWHH----------MPHPSDSERIRQYLPRNPCPT-------PPYHHQMPPPH 656
QQ ++ HH PHP + P P+ PP +PPPH
Sbjct: 494 QQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPH 553
Query: 657 S 657
S
Sbjct: 554 S 554
Score = 63.2 bits (152), Expect = 9e-10
Identities = 109/428 (25%), Positives = 145/428 (33%), Gaps = 98/428 (22%)
Query: 235 PQALVATSPPS---HSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRS 291
P + A +PP +S SSS+ +S++S+SP P S A + +S
Sbjct: 361 PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPP----- 415
Query: 292 TDSEVSQSPAKNGSKPVHSNQ-HPQSPAVPPTY----------PSGPPPAASALSTTP-- 338
T VS P K + S Q P PP Y P PP+ A ST
Sbjct: 416 TSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPP 475
Query: 339 -----------------------------GNNGVPAPAAPPSALGPKASPAPSHNSGTPA 369
GN+G P P A P L SH++
Sbjct: 476 VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPL----EGGSSHHAH--- 528
Query: 370 PYAQAVA----PPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGG------ 419
PYA + + P P GP+ P V S G G SS+SS+S++ G
Sbjct: 529 PYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHP 588
Query: 420 ---AGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAA 476
G Q + V + + LS+ ASS A + P PPP + PS A
Sbjct: 589 SPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGA 648
Query: 477 PTGA--GGVAPGSGNNSGGPSLLVPLP-----VNPPSSP------TPSFSDAKAAGALLN 523
A G PGS PS P +PP+ P +P+ A +
Sbjct: 649 YKTATPPGYKPGS-----PPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPS 703
Query: 524 GPPQFSTAPEIKAP-EPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASA 582
G P P A PLS+ + E A E PVP S S PP
Sbjct: 704 GLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPAR---------SPSPPPKVV 754
Query: 583 QPPLQLSE 590
P S+
Sbjct: 755 DVPSHASQ 762
Score = 55.5 bits (132), Expect = 2e-07
Identities = 71/271 (26%), Positives = 96/271 (35%), Gaps = 49/271 (18%)
Query: 263 STTSSSPIPPSPANCTTENSEDDKKRGRS-----TDSEVSQSPAKNGSKPVHSNQHPQSP 317
S S P PP PA+ +S+ + + S S S GS P Q P
Sbjct: 535 SLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGP 594
Query: 318 AVPPTYPSGPPPAASALSTT------------------------PGNNGVPAPAAPPSAL 353
P YP P P + S T P P+P A +A
Sbjct: 595 QGAP-YPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTAT 653
Query: 354 GPKASPA--PSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSS 411
P P PS +GTP Y + +PPA GP T +P P+V P G +G G S
Sbjct: 654 PPGYKPGSPPSFRTGTPPGY-RGTSPPA--GPGTFKPGSPTVGP--GPLPPAGPSGLPSL 708
Query: 412 SNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKE 471
A +G AT + PAE + ++ PP+ +PPP
Sbjct: 709 PPPPAAPASGPPLSATQ----IKQEPAE--------EYETPESPVPPARSPSPPPKVVDV 756
Query: 472 PSAAAPTGAGGVAPGSGNNSGGPSLLVPLPV 502
PS A+ + G NS S L +P+
Sbjct: 757 PSHASQSARFNKHLDRGFNSCARSDLYFVPL 787
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 77.8 bits (190), Expect = 3e-14
Identities = 72/272 (26%), Positives = 84/272 (30%), Gaps = 35/272 (12%)
Query: 300 PAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVP-----------APAA 348
P K P PQ P PP P GPPP P G P +P +
Sbjct: 54 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS 113
Query: 349 PPSALGPKASPAPSHN--SGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGG 406
PP P+ P N G P P + PP P G + Q PP +P G G
Sbjct: 114 PPGK--PQGPPPQGGNQPQGPPPPPGKPQGPP-PQGGNKPQGPPPPGKPQGPPPQGDNKS 170
Query: 407 GSSSSSNSSAGG----GAGKQNGATSYSSVVADSPAEVALSSSG-------------GNN 449
SS S G G + G P + G G+N
Sbjct: 171 RSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDN 230
Query: 450 ASSQALGPPSGPHNPPPSTSKEPSAAAPTGA--GGVAPGSGNNSGGPSLLVPLPVNPPSS 507
S A PP P PPP +P P G P GN GP PP
Sbjct: 231 KSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 290
Query: 508 PTPSFSDAKAAGALLNGPPQFSTAPEIKAPEP 539
+ S S G PPQ P+ P P
Sbjct: 291 GSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPP 322
Score = 76.6 bits (187), Expect = 8e-14
Identities = 84/310 (27%), Positives = 96/310 (30%), Gaps = 28/310 (9%)
Query: 255 NQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPV----HS 310
NQ P PP N K +G + S+SP KP
Sbjct: 66 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 125
Query: 311 NQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAP 370
PQ P PP P GPPP P G P P ++S +P P P
Sbjct: 126 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPP 185
Query: 371 YA--QAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSN--SSAGGGAGKQNGA 426
Q PP P G P +P G G G N SA GK G
Sbjct: 186 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGP 245
Query: 427 TSYSSVVADSPAEVALSSSG----GNNASSQALGPPSGPHNPPP-STSKEPSAAAPTG-A 480
P G G N Q PP P PPP SK S+ +P G
Sbjct: 246 PPQGGNQPQGPPPPPGKPQGPPPQGGN-KPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKP 304
Query: 481 GGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPL 540
G P GN GP P P P P P + K G G PQ P P
Sbjct: 305 QGPPPQGGNQPQGP----PPPPGKPQGPPPQGGN-KPQGPPPPGKPQ--------GPPPQ 351
Query: 541 SSLKSMAERA 550
KS + R+
Sbjct: 352 GGSKSRSARS 361
Score = 72.4 bits (176), Expect = 1e-12
Identities = 69/269 (25%), Positives = 86/269 (31%), Gaps = 30/269 (11%)
Query: 278 TTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPP-AASALST 336
+ +N +D + S S ++ +P G+ P N+ PQ P PP P GPPP +
Sbjct: 15 SAQNLNEDVSQEESP-SLIAGNP--QGAPPQGGNK-PQGPPSPPGKPQGPPPQGGNQPQG 70
Query: 337 TPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPS 396
P G P P P+ P P G P P G + PR P +P
Sbjct: 71 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQG-----------PPPQGDKSRSPRSPPGKPQ 119
Query: 397 G----GGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASS 452
G GG G G K G P G+N S
Sbjct: 120 GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ--------GDNKSR 171
Query: 453 QALGPPSGPHNPPPSTSKEPSAAAPTGA--GGVAPGSGNNSGGPSLLVPLPVNPPSSPTP 510
+ PP P PPP +P P G P GN GP PP
Sbjct: 172 SSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNK 231
Query: 511 SFSDAKAAGALLNGPPQFSTAPEIKAPEP 539
S S G PPQ P+ P P
Sbjct: 232 SQSARSPPGKPQGPPPQGGNQPQGPPPPP 260
Score = 65.9 bits (159), Expect = 1e-10
Identities = 70/274 (25%), Positives = 86/274 (31%), Gaps = 45/274 (16%)
Query: 269 PIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTY----P 324
P PP ++ + RS + P + G++P P P PP P
Sbjct: 153 PPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 212
Query: 325 SGPPPAASALSTTP-GNNGVPAPAAPPSALGPKASPAPSHNS--GTPAPYAQAVAPPAPS 381
GPPP P G+N + +PP P+ P N G P P + PP P
Sbjct: 213 QGPPPPGKPQGPPPQGDNKSQSARSPPGK--PQGPPPQGGNQPQGPPPPPGKPQGPP-PQ 269
Query: 382 GPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAG--------GG---------AGKQN 424
G + Q PP +P G GG S SS S G GG GK
Sbjct: 270 GGNKPQGPPPPGKPQGPP---PQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 326
Query: 425 GATSYSSVVADSPAEVALSSSG---GNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGAG 481
G P G + S A PP P PP P P G
Sbjct: 327 GPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGG 386
Query: 482 G----VAPGSGNNSGGPSLLVPLPVNPPSSPTPS 511
AP +G G P PP PS
Sbjct: 387 NPQQPQAPPAGQPQG--------PPRPPQGGRPS 412
>gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]
Length = 558
Score = 77.4 bits (189), Expect = 5e-14
Identities = 60/197 (30%), Positives = 86/197 (43%), Gaps = 24/197 (12%)
Query: 343 VPAPAAPPSALGPKASP----------APSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPS 392
VPA PP+ L P P S +S T +P A ++ PPA SGP+ +P P +
Sbjct: 3 VPAALIPPTQLVPPQPPISTSASSSGTTTSTSSATSSP-APSIGPPASSGPTLFRPEPIA 61
Query: 393 VQPS----------GGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVAL 442
+ GGGGGGSGGGG SS + GGG G N + ++ S
Sbjct: 62 SAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGG 121
Query: 443 SSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPV 502
S+GG ASS + +G + S+S S+++ + + + G G P P PV
Sbjct: 122 ISAGGGVASSTPINASTG--SSSSSSSSSSSSSSSSSSSSSSSSCGPLPGKPVYSTPSPV 179
Query: 503 -NPPSSPTPSFSDAKAA 518
N P + D + A
Sbjct: 180 ENTPQNNECKMVDLRGA 196
Score = 39.7 bits (91), Expect = 0.010
Identities = 59/237 (24%), Positives = 83/237 (35%), Gaps = 65/237 (27%)
Query: 234 IPQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTD 293
+P AL+ PP+ + S+S+ +TTS+S SPA
Sbjct: 3 VPAALI---PPTQLVPPQPPISTSASSSGTTTSTSSATSSPAPSI--------------- 44
Query: 294 SEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSAL 353
PA +G P + P AA+A T+ G G
Sbjct: 45 ----GPPASSG------------PTLFRPEPIASAAAAAATVTSTGGGG--------GGG 80
Query: 354 GPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGG--SGGGGSSSS 411
G S N G G S P + GGGGG S GGG +SS
Sbjct: 81 GSGGGGGSSGNGG---------GGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASS 131
Query: 412 SNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGP-PSGPHNPPPS 467
+ +A G+ + ++S SS SSS +++SS + GP P P PS
Sbjct: 132 TPINASTGSSSSSSSSSSSS-----------SSSSSSSSSSSSCGPLPGKPVYSTPS 177
>gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]
Length = 706
Score = 77.4 bits (189), Expect = 5e-14
Identities = 60/197 (30%), Positives = 86/197 (43%), Gaps = 24/197 (12%)
Query: 343 VPAPAAPPSALGPKASP----------APSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPS 392
VPA PP+ L P P S +S T +P A ++ PPA SGP+ +P P +
Sbjct: 3 VPAALIPPTQLVPPQPPISTSASSSGTTTSTSSATSSP-APSIGPPASSGPTLFRPEPIA 61
Query: 393 VQPS----------GGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVAL 442
+ GGGGGGSGGGG SS + GGG G N + ++ S
Sbjct: 62 SAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGG 121
Query: 443 SSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPV 502
S+GG ASS + +G + S+S S+++ + + + G G P P PV
Sbjct: 122 ISAGGGVASSTPINASTG--SSSSSSSSSSSSSSSSSSSSSSSSCGPLPGKPVYSTPSPV 179
Query: 503 -NPPSSPTPSFSDAKAA 518
N P + D + A
Sbjct: 180 ENTPQNNECKMVDLRGA 196
Score = 39.7 bits (91), Expect = 0.010
Identities = 59/237 (24%), Positives = 83/237 (35%), Gaps = 65/237 (27%)
Query: 234 IPQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTD 293
+P AL+ PP+ + S+S+ +TTS+S SPA
Sbjct: 3 VPAALI---PPTQLVPPQPPISTSASSSGTTTSTSSATSSPAPSI--------------- 44
Query: 294 SEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSAL 353
PA +G P + P AA+A T+ G G
Sbjct: 45 ----GPPASSG------------PTLFRPEPIASAAAAAATVTSTGGGG--------GGG 80
Query: 354 GPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGG--SGGGGSSSS 411
G S N G G S P + GGGGG S GGG +SS
Sbjct: 81 GSGGGGGSSGNGG---------GGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASS 131
Query: 412 SNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGP-PSGPHNPPPS 467
+ +A G+ + ++S SS SSS +++SS + GP P P PS
Sbjct: 132 TPINASTGSSSSSSSSSSSS-----------SSSSSSSSSSSSCGPLPGKPVYSTPS 177
>gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]
Length = 504
Score = 77.4 bits (189), Expect = 5e-14
Identities = 60/197 (30%), Positives = 86/197 (43%), Gaps = 24/197 (12%)
Query: 343 VPAPAAPPSALGPKASP----------APSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPS 392
VPA PP+ L P P S +S T +P A ++ PPA SGP+ +P P +
Sbjct: 3 VPAALIPPTQLVPPQPPISTSASSSGTTTSTSSATSSP-APSIGPPASSGPTLFRPEPIA 61
Query: 393 VQPS----------GGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVAL 442
+ GGGGGGSGGGG SS + GGG G N + ++ S
Sbjct: 62 SAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGG 121
Query: 443 SSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPV 502
S+GG ASS + +G + S+S S+++ + + + G G P P PV
Sbjct: 122 ISAGGGVASSTPINASTG--SSSSSSSSSSSSSSSSSSSSSSSSCGPLPGKPVYSTPSPV 179
Query: 503 -NPPSSPTPSFSDAKAA 518
N P + D + A
Sbjct: 180 ENTPQNNECKMVDLRGA 196
Score = 39.7 bits (91), Expect = 0.010
Identities = 59/237 (24%), Positives = 83/237 (35%), Gaps = 65/237 (27%)
Query: 234 IPQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTD 293
+P AL+ PP+ + S+S+ +TTS+S SPA
Sbjct: 3 VPAALI---PPTQLVPPQPPISTSASSSGTTTSTSSATSSPAPSI--------------- 44
Query: 294 SEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSAL 353
PA +G P + P AA+A T+ G G
Sbjct: 45 ----GPPASSG------------PTLFRPEPIASAAAAAATVTSTGGGG--------GGG 80
Query: 354 GPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGG--SGGGGSSSS 411
G S N G G S P + GGGGG S GGG +SS
Sbjct: 81 GSGGGGGSSGNGG---------GGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASS 131
Query: 412 SNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGP-PSGPHNPPPS 467
+ +A G+ + ++S SS SSS +++SS + GP P P PS
Sbjct: 132 TPINASTGSSSSSSSSSSSS-----------SSSSSSSSSSSSCGPLPGKPVYSTPS 177
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 77.0 bits (188), Expect = 6e-14
Identities = 137/533 (25%), Positives = 181/533 (33%), Gaps = 109/533 (20%)
Query: 250 EDEIFNQSSSTPTSTTS-SSPIPPSPANCTTENSEDDKKRGRSTDSEVSQ---------- 298
+ E +++SS T T S P PS + +S G S ++ Q
Sbjct: 103 DTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIP 162
Query: 299 SPAKNGSKPVHSNQHPQSPAVPPTY--PSGPPPAASALSTTPGNNGVPAPAAPPSAL--- 353
SP N S S Q A PP P+G PA S S PG +P P PSA
Sbjct: 163 SPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPS--SAPPGTPQLPTPGPTPSATAVP 220
Query: 354 ---GPKASPAPS----------HNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGG 400
P AS AP+ H AP PP+P P P PP +QP G
Sbjct: 221 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPP-LQPLTGSA 279
Query: 401 G-------------GSGGGGSSS------------------SSNSSAGGGAGKQNGATSY 429
G G G G S +S G + A +Y
Sbjct: 280 GQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAY 339
Query: 430 SSVVADSPA-EVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTG------AGG 482
PA + AL S P + PH PP T+ P AP G
Sbjct: 340 PHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG 399
Query: 483 VAPGSGN-NSGGPSLLVPLPV----NPPSSPTPSFSDAKAAGALLNGP------PQFSTA 531
+P S N N P L PL +PPS+ P + L + P Q
Sbjct: 400 PSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNL 459
Query: 532 PEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPA----SAQPPLQ 587
P A P + L +A + + P +T STS PPA SAQPP
Sbjct: 460 PPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPP--TCPSTSTPPAGPGTSAQPPCS 517
Query: 588 LSEVNIPLSLG--VCPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPT 645
+ + G CPL V Q+ ++A+++A P P PR+P P
Sbjct: 518 GAAASGGSIAGGSSCPLPTV-----QIKEEALDDAEEPESPPPP---------PRSPSPE 563
Query: 646 PPYHHQMPPPHSDTVEFYQRL-----STETLFFIFYYLEGTKAQYLAAKALKK 693
P P S + FY+ L S F L G+K +A++K
Sbjct: 564 PTV-VDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEK 615
Score = 57.8 bits (138), Expect = 4e-08
Identities = 88/367 (23%), Positives = 118/367 (32%), Gaps = 87/367 (23%)
Query: 240 ATSPPSHSHMEDEIFNQSSSTPTSTTSSS----PIPPSPANCTTENSEDDKKRGRSTDSE 295
A P + SH + + Q P S + P PP P +
Sbjct: 279 AGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQ--------------- 323
Query: 296 VSQSPAKNGSKPVHSNQHP--QSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSAL 353
SQ A G+ P + H Q PA S PP L PAP A P
Sbjct: 324 ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP--------PAPLAMPHIK 375
Query: 354 GPKASPAPSHNSGTPAPYAQAVAP----PAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSS 409
P +P P PAP A P P+P + P PP+++P S
Sbjct: 376 PPPTTPIPQ----LPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPL------------S 419
Query: 410 SSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTS 469
S S S + SPA+ + N A PP+G H P
Sbjct: 420 SLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAP--- 476
Query: 470 KEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFS 529
+ P A P GG P P+ PP+ P+ S PP
Sbjct: 477 QPPFAQHPFVPGG----------------PPPITPPTCPSTS------------TPP--- 505
Query: 530 TAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTER--DIILSSTSAPPASAQPPLQ 587
P A P S + A +I+ G P+PT+ + E D S PP P +
Sbjct: 506 AGPGTSAQPPCSG--AAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPE 563
Query: 588 LSEVNIP 594
+ V+ P
Sbjct: 564 PTVVDTP 570
Score = 47.8 bits (112), Expect = 4e-05
Identities = 66/251 (26%), Positives = 95/251 (37%), Gaps = 26/251 (10%)
Query: 236 QALVATSPPS-HSHMEDEI-FNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTD 293
QA + TSP + + H ++ +QS+ P+PP+P
Sbjct: 328 QAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPT-------- 379
Query: 294 SEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSAL 353
+ + Q PA K P ++ P PPPA LS+ ++ P+ PP L
Sbjct: 380 TPIPQLPAPQAHKHPPHLSGPSPFSMNANLP--PPPALKPLSSLSTHHP-PSAHPPPLQL 436
Query: 354 GPKASPAPSHNSGTPA-PYAQAVAPPAPSGPST----TQPRPPSVQPSGGGGGGSGGGGS 408
P++ P PS + P +Q + PP S P T P+PP Q GG
Sbjct: 437 MPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPP 496
Query: 409 SSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSS---GGNNASSQALGPPSGPHNPP 465
+ S S+ G G A S A S +A SS +AL P +PP
Sbjct: 497 TCPSTSTPPAGPG--TSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP 554
Query: 466 P---STSKEPS 473
P S S EP+
Sbjct: 555 PPPRSPSPEPT 565
Score = 46.2 bits (108), Expect = 1e-04
Identities = 87/396 (21%), Positives = 131/396 (33%), Gaps = 48/396 (12%)
Query: 283 EDDKKRG----RSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTP 338
EDD G R+ S S S ++G K ++ ++ + S + SA ST+
Sbjct: 8 EDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTS- 66
Query: 339 GNNGVPAPAAPPSALGPK---ASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQP 395
+N A SA K +SP S+ + VA T+ + + +
Sbjct: 67 -SNDSKAETVKKSAKKVKEEASSPLKSNKR-----QREKVASDTEEADRTSSKKTKTQEI 120
Query: 396 SGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQAL 455
S G G SS S + + G + ++ S P+ S ++A Q L
Sbjct: 121 SRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQML 180
Query: 456 GPPSGPHNPPPSTSKEPSAAAPTGAGGVAPGSGNNS------GGPSL-LVPLPVNPPSSP 508
P + PS+A P PG ++ G P+ P P++P
Sbjct: 181 QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP 240
Query: 509 TPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPV-----PTL 563
P +A PP P PL L A + + S + P+ P
Sbjct: 241 VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP 300
Query: 564 HLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVCPLGPVPLTKEQLYQQAMEEAAWH 623
H + +L P PP Q S+ P LG P P T QL
Sbjct: 301 HSLQAGPLLQHPGPPQPFGLPP-QASQGQAP--LGTSPAAAYPHTSLQL----------- 346
Query: 624 HMPHPSDSERIRQYLPRNPCPTPP----YHHQMPPP 655
P+ ++ P P PP H PPP
Sbjct: 347 ----PASQSALQSQQPPREQPLPPAPLAMPHIKPPP 378
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 77.0 bits (188), Expect = 6e-14
Identities = 137/533 (25%), Positives = 181/533 (33%), Gaps = 109/533 (20%)
Query: 250 EDEIFNQSSSTPTSTTS-SSPIPPSPANCTTENSEDDKKRGRSTDSEVSQ---------- 298
+ E +++SS T T S P PS + +S G S ++ Q
Sbjct: 657 DTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIP 716
Query: 299 SPAKNGSKPVHSNQHPQSPAVPPTY--PSGPPPAASALSTTPGNNGVPAPAAPPSAL--- 353
SP N S S Q A PP P+G PA S S PG +P P PSA
Sbjct: 717 SPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPS--SAPPGTPQLPTPGPTPSATAVP 774
Query: 354 ---GPKASPAPS----------HNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGG 400
P AS AP+ H AP PP+P P P PP +QP G
Sbjct: 775 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPP-LQPLTGSA 833
Query: 401 G-------------GSGGGGSSS------------------SSNSSAGGGAGKQNGATSY 429
G G G G S +S G + A +Y
Sbjct: 834 GQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAY 893
Query: 430 SSVVADSPA-EVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTG------AGG 482
PA + AL S P + PH PP T+ P AP G
Sbjct: 894 PHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG 953
Query: 483 VAPGSGN-NSGGPSLLVPLPV----NPPSSPTPSFSDAKAAGALLNGP------PQFSTA 531
+P S N N P L PL +PPS+ P + L + P Q
Sbjct: 954 PSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNL 1013
Query: 532 PEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPA----SAQPPLQ 587
P A P + L +A + + P +T STS PPA SAQPP
Sbjct: 1014 PPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPP--TCPSTSTPPAGPGTSAQPPCS 1071
Query: 588 LSEVNIPLSLG--VCPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPT 645
+ + G CPL V Q+ ++A+++A P P PR+P P
Sbjct: 1072 GAAASGGSIAGGSSCPLPTV-----QIKEEALDDAEEPESPPPP---------PRSPSPE 1117
Query: 646 PPYHHQMPPPHSDTVEFYQRL-----STETLFFIFYYLEGTKAQYLAAKALKK 693
P P S + FY+ L S F L G+K +A++K
Sbjct: 1118 PTV-VDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEK 1169
Score = 57.8 bits (138), Expect = 4e-08
Identities = 88/367 (23%), Positives = 118/367 (32%), Gaps = 87/367 (23%)
Query: 240 ATSPPSHSHMEDEIFNQSSSTPTSTTSSS----PIPPSPANCTTENSEDDKKRGRSTDSE 295
A P + SH + + Q P S + P PP P +
Sbjct: 833 AGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQ--------------- 877
Query: 296 VSQSPAKNGSKPVHSNQHP--QSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSAL 353
SQ A G+ P + H Q PA S PP L PAP A P
Sbjct: 878 ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP--------PAPLAMPHIK 929
Query: 354 GPKASPAPSHNSGTPAPYAQAVAP----PAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSS 409
P +P P PAP A P P+P + P PP+++P S
Sbjct: 930 PPPTTPIPQ----LPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPL------------S 973
Query: 410 SSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTS 469
S S S + SPA+ + N A PP+G H P
Sbjct: 974 SLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAP--- 1030
Query: 470 KEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFS 529
+ P A P GG P P+ PP+ P+ S PP
Sbjct: 1031 QPPFAQHPFVPGG----------------PPPITPPTCPSTS------------TPP--- 1059
Query: 530 TAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTER--DIILSSTSAPPASAQPPLQ 587
P A P S + A +I+ G P+PT+ + E D S PP P +
Sbjct: 1060 AGPGTSAQPPCSG--AAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPE 1117
Query: 588 LSEVNIP 594
+ V+ P
Sbjct: 1118 PTVVDTP 1124
Score = 50.8 bits (120), Expect = 5e-06
Identities = 90/410 (21%), Positives = 135/410 (32%), Gaps = 48/410 (11%)
Query: 269 PIPPSPANCTTENSEDDKKRG----RSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYP 324
P+ P P EDD G R+ S S S ++G K ++ ++ +
Sbjct: 548 PVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIR 607
Query: 325 SGPPPAASALSTTPGNNGVPAPAAPPSALGPK---ASPAPSHNSGTPAPYAQAVAPPAPS 381
S + SA ST+ +N A SA K +SP S+ + VA
Sbjct: 608 SSGRNSPSAASTS--SNDSKAETVKKSAKKVKEEASSPLKSNKR-----QREKVASDTEE 660
Query: 382 GPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVA 441
T+ + + + S G G SS S + + G + ++ S P+
Sbjct: 661 ADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQD 720
Query: 442 LSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPGSGNNS------GGPS 495
S ++A Q L P + PS+A P PG ++ G P+
Sbjct: 721 NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPT 780
Query: 496 L-LVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAERAAISS 554
P P++P P +A PP P PL L A + + S
Sbjct: 781 ASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPS 840
Query: 555 GIEDPV-----PTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVCPLGPVPLTK 609
+ P+ P H + +L P PP Q S+ P LG P P T
Sbjct: 841 HAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPP-QASQGQAP--LGTSPAAAYPHTS 897
Query: 610 EQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPP----YHHQMPPP 655
QL P+ ++ P P PP H PPP
Sbjct: 898 LQL---------------PASQSALQSQQPPREQPLPPAPLAMPHIKPPP 932
Score = 47.8 bits (112), Expect = 4e-05
Identities = 66/251 (26%), Positives = 95/251 (37%), Gaps = 26/251 (10%)
Query: 236 QALVATSPPS-HSHMEDEI-FNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTD 293
QA + TSP + + H ++ +QS+ P+PP+P
Sbjct: 882 QAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPT-------- 933
Query: 294 SEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSAL 353
+ + Q PA K P ++ P PPPA LS+ ++ P+ PP L
Sbjct: 934 TPIPQLPAPQAHKHPPHLSGPSPFSMNANLP--PPPALKPLSSLSTHHP-PSAHPPPLQL 990
Query: 354 GPKASPAPSHNSGTPA-PYAQAVAPPAPSGPST----TQPRPPSVQPSGGGGGGSGGGGS 408
P++ P PS + P +Q + PP S P T P+PP Q GG
Sbjct: 991 MPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPP 1050
Query: 409 SSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSS---GGNNASSQALGPPSGPHNPP 465
+ S S+ G G A S A S +A SS +AL P +PP
Sbjct: 1051 TCPSTSTPPAGPG--TSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP 1108
Query: 466 P---STSKEPS 473
P S S EP+
Sbjct: 1109 PPPRSPSPEPT 1119
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 77.0 bits (188), Expect = 6e-14
Identities = 137/533 (25%), Positives = 181/533 (33%), Gaps = 109/533 (20%)
Query: 250 EDEIFNQSSSTPTSTTS-SSPIPPSPANCTTENSEDDKKRGRSTDSEVSQ---------- 298
+ E +++SS T T S P PS + +S G S ++ Q
Sbjct: 657 DTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIP 716
Query: 299 SPAKNGSKPVHSNQHPQSPAVPPTY--PSGPPPAASALSTTPGNNGVPAPAAPPSAL--- 353
SP N S S Q A PP P+G PA S S PG +P P PSA
Sbjct: 717 SPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPS--SAPPGTPQLPTPGPTPSATAVP 774
Query: 354 ---GPKASPAPS----------HNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGG 400
P AS AP+ H AP PP+P P P PP +QP G
Sbjct: 775 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPP-LQPLTGSA 833
Query: 401 G-------------GSGGGGSSS------------------SSNSSAGGGAGKQNGATSY 429
G G G G S +S G + A +Y
Sbjct: 834 GQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAY 893
Query: 430 SSVVADSPA-EVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTG------AGG 482
PA + AL S P + PH PP T+ P AP G
Sbjct: 894 PHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG 953
Query: 483 VAPGSGN-NSGGPSLLVPLPV----NPPSSPTPSFSDAKAAGALLNGP------PQFSTA 531
+P S N N P L PL +PPS+ P + L + P Q
Sbjct: 954 PSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNL 1013
Query: 532 PEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPA----SAQPPLQ 587
P A P + L +A + + P +T STS PPA SAQPP
Sbjct: 1014 PPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPP--TCPSTSTPPAGPGTSAQPPCS 1071
Query: 588 LSEVNIPLSLG--VCPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPT 645
+ + G CPL V Q+ ++A+++A P P PR+P P
Sbjct: 1072 GAAASGGSIAGGSSCPLPTV-----QIKEEALDDAEEPESPPPP---------PRSPSPE 1117
Query: 646 PPYHHQMPPPHSDTVEFYQRL-----STETLFFIFYYLEGTKAQYLAAKALKK 693
P P S + FY+ L S F L G+K +A++K
Sbjct: 1118 PTV-VDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEK 1169
Score = 57.8 bits (138), Expect = 4e-08
Identities = 88/367 (23%), Positives = 118/367 (32%), Gaps = 87/367 (23%)
Query: 240 ATSPPSHSHMEDEIFNQSSSTPTSTTSSS----PIPPSPANCTTENSEDDKKRGRSTDSE 295
A P + SH + + Q P S + P PP P +
Sbjct: 833 AGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQ--------------- 877
Query: 296 VSQSPAKNGSKPVHSNQHP--QSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSAL 353
SQ A G+ P + H Q PA S PP L PAP A P
Sbjct: 878 ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP--------PAPLAMPHIK 929
Query: 354 GPKASPAPSHNSGTPAPYAQAVAP----PAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSS 409
P +P P PAP A P P+P + P PP+++P S
Sbjct: 930 PPPTTPIPQ----LPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPL------------S 973
Query: 410 SSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTS 469
S S S + SPA+ + N A PP+G H P
Sbjct: 974 SLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAP--- 1030
Query: 470 KEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFS 529
+ P A P GG P P+ PP+ P+ S PP
Sbjct: 1031 QPPFAQHPFVPGG----------------PPPITPPTCPSTS------------TPP--- 1059
Query: 530 TAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTER--DIILSSTSAPPASAQPPLQ 587
P A P S + A +I+ G P+PT+ + E D S PP P +
Sbjct: 1060 AGPGTSAQPPCSG--AAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPE 1117
Query: 588 LSEVNIP 594
+ V+ P
Sbjct: 1118 PTVVDTP 1124
Score = 50.8 bits (120), Expect = 5e-06
Identities = 90/410 (21%), Positives = 135/410 (32%), Gaps = 48/410 (11%)
Query: 269 PIPPSPANCTTENSEDDKKRG----RSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYP 324
P+ P P EDD G R+ S S S ++G K ++ ++ +
Sbjct: 548 PVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIR 607
Query: 325 SGPPPAASALSTTPGNNGVPAPAAPPSALGPK---ASPAPSHNSGTPAPYAQAVAPPAPS 381
S + SA ST+ +N A SA K +SP S+ + VA
Sbjct: 608 SSGRNSPSAASTS--SNDSKAETVKKSAKKVKEEASSPLKSNKR-----QREKVASDTEE 660
Query: 382 GPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVA 441
T+ + + + S G G SS S + + G + ++ S P+
Sbjct: 661 ADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQD 720
Query: 442 LSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPGSGNNS------GGPS 495
S ++A Q L P + PS+A P PG ++ G P+
Sbjct: 721 NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPT 780
Query: 496 L-LVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAERAAISS 554
P P++P P +A PP P PL L A + + S
Sbjct: 781 ASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPS 840
Query: 555 GIEDPV-----PTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVCPLGPVPLTK 609
+ P+ P H + +L P PP Q S+ P LG P P T
Sbjct: 841 HAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPP-QASQGQAP--LGTSPAAAYPHTS 897
Query: 610 EQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPP----YHHQMPPP 655
QL P+ ++ P P PP H PPP
Sbjct: 898 LQL---------------PASQSALQSQQPPREQPLPPAPLAMPHIKPPP 932
Score = 47.8 bits (112), Expect = 4e-05
Identities = 66/251 (26%), Positives = 95/251 (37%), Gaps = 26/251 (10%)
Query: 236 QALVATSPPS-HSHMEDEI-FNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTD 293
QA + TSP + + H ++ +QS+ P+PP+P
Sbjct: 882 QAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPT-------- 933
Query: 294 SEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSAL 353
+ + Q PA K P ++ P PPPA LS+ ++ P+ PP L
Sbjct: 934 TPIPQLPAPQAHKHPPHLSGPSPFSMNANLP--PPPALKPLSSLSTHHP-PSAHPPPLQL 990
Query: 354 GPKASPAPSHNSGTPA-PYAQAVAPPAPSGPST----TQPRPPSVQPSGGGGGGSGGGGS 408
P++ P PS + P +Q + PP S P T P+PP Q GG
Sbjct: 991 MPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPP 1050
Query: 409 SSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSS---GGNNASSQALGPPSGPHNPP 465
+ S S+ G G A S A S +A SS +AL P +PP
Sbjct: 1051 TCPSTSTPPAGPG--TSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP 1108
Query: 466 P---STSKEPS 473
P S S EP+
Sbjct: 1109 PPPRSPSPEPT 1119
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 75.5 bits (184), Expect = 2e-13
Identities = 73/247 (29%), Positives = 98/247 (39%), Gaps = 41/247 (16%)
Query: 303 NGSKPVHSNQHPQSPAVP-------PTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGP 355
NGS + ++ H +PAV P P A + TP G AP A P+A P
Sbjct: 199 NGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPA-PAAPSP 257
Query: 356 KASPAPSHNSGT-----PAPYAQAVAPPAPSGPSTTQPR--PPSVQPSGGGGGG------ 402
A+PAP+ + PAP A P P+GP T P PP+ +GG G
Sbjct: 258 PAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAP 317
Query: 403 SGGGGSSSSSNSSAGGGAGKQNGATSYSS----VVADSPAEVALSSSG-GNNASSQALGP 457
+ GG + S G A S V A PA L++SG + A+S +GP
Sbjct: 318 AAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGP 377
Query: 458 PSGPHNPPPSTSKEPSAAAPTG-----AGGVAPG-----SGNNSG-----GPSLLVPLPV 502
P P+ P+ PTG AG V + SG P++L P
Sbjct: 378 TMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLP 437
Query: 503 NPPSSPT 509
PP +PT
Sbjct: 438 QPPQNPT 444
Score = 67.8 bits (164), Expect = 4e-11
Identities = 79/309 (25%), Positives = 114/309 (36%), Gaps = 37/309 (11%)
Query: 314 PQSPAVP----PTYPSGPPPAASALSTTP-GNNGVPAPAAPPSALGPKASPAPSHNSGTP 368
PQ P P P P+GP P A+ L P G+ G AP +A+ PAP+ +
Sbjct: 102 PQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPA 161
Query: 369 APYAQAV-APPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSS--SSSNSSAGGGAGKQNG 425
P A A A P P P P +P+G G + G ++ +S +++A + NG
Sbjct: 162 GPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNG 221
Query: 426 ATSYSSV-----------------VADSPAEVALSSSGGNNASSQALGPPSGPHNPPPST 468
+ + A PA A S ++ A PP P P P+T
Sbjct: 222 PAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPP--PAPAT 279
Query: 469 SKEP---SAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGP 525
P A PT A V P + +GG + P P P + S GA P
Sbjct: 280 LARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPA-PAAGGPAGVSGQPGPGAAAAAP 338
Query: 526 PQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPP 585
AP +KA P +++ A AA + P T + PA+ PP
Sbjct: 339 -----APGVKAESPKRVVQA-APPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPP 392
Query: 586 LQLSEVNIP 594
+ +P
Sbjct: 393 APGTPTGLP 401
Score = 53.5 bits (127), Expect = 7e-07
Identities = 93/364 (25%), Positives = 135/364 (37%), Gaps = 47/364 (12%)
Query: 281 NSEDDKKRGR----STDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALST 336
NSE D+K S +S+++ S A H + P++P V AA AL
Sbjct: 14 NSEVDEKVVSDLVGSLESQLAASAAH------HHHLAPRTPEVRAA-------AAGAL-- 58
Query: 337 TPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPS---- 392
GN+ V A + GP A+PA P P A P GP +P PPS
Sbjct: 59 --GNHVVSGSPAGAAGAGP-AAPAEGAPGAAPEPPPAGRARPGGGGPQ--RPGPPSPRRP 113
Query: 393 VQPSGGGGGGS-------GGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSS 445
+ P+G + G GS + ++A AG + A + + A A A +
Sbjct: 114 LVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPE-PAPAGPAKPAGPAALAARAGP 172
Query: 446 GGNNASSQALGP-PSGPHNPPPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNP 504
G GP P P P + + SAA AP + GP+ L+PLP
Sbjct: 173 GPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLP--K 230
Query: 505 PSSP-----TPSFSDAKAAGALLNGPPQFSTAPEIKA---PEPLSSLKSMAERAAISSGI 556
P++P TP F A A A P + AP A P P + ++A +G
Sbjct: 231 PAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGP 290
Query: 557 EDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVCPLGPVPLTKEQLYQQA 616
P + S A PA A + V+ G P P K + ++
Sbjct: 291 PTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRV 350
Query: 617 MEEA 620
++ A
Sbjct: 351 VQAA 354
Score = 33.1 bits (74), Expect = 0.97
Identities = 39/188 (20%), Positives = 62/188 (32%), Gaps = 21/188 (11%)
Query: 256 QSSSTPTSTTSSSPIPP-SPANCTTENSEDDKKRGRSTDSEVSQSPAKN-GSKPVHSNQH 313
+++ TPT P PP +P N RS + ++ P + ++
Sbjct: 424 RATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQ 483
Query: 314 PQSPAVP-PTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYA 372
PQ+ P P P+ PP + PG + P + +
Sbjct: 484 PQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTTII------------------K 525
Query: 373 QAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSV 432
Q PS T R P VQP GG + +++ G GAT+ SS
Sbjct: 526 QVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPGATTTSSA 585
Query: 433 VADSPAEV 440
++ V
Sbjct: 586 ATETMENV 593
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 75.1 bits (183), Expect = 2e-13
Identities = 118/426 (27%), Positives = 155/426 (36%), Gaps = 99/426 (23%)
Query: 257 SSSTPTSTTSSSPIP---PSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQH 313
SS++ STT SP PS + R S+ + SPA++G + +
Sbjct: 210 SSASEHSTTEPSPAARRRPSAGG----GLQRPASRSLSSSATPLSSPARSGPSARGTPRA 265
Query: 314 PQSPAVPPTYPSG----------PP-----PAASALSTTPGNNGVPAPAAPPSALGPKAS 358
P P+ P P G PP PA LS++P P+P+A + P
Sbjct: 266 PAHPSQPK--PKGLQALRPPQVTPPRKDAAPALGPLSSSP--LATPSPSAALQSQAPPTL 321
Query: 359 PAPSHNSG------TPAPYAQAVAPPAPSGPSTTQ--PRPPSVQPSGGGGGGSGGGGSSS 410
PA H+S TP P +APP+PS P + Q P PP+ PS
Sbjct: 322 PATPHSSSLTCQLATPLP----LAPPSPSAPPSLQTLPSPPATPPS-------------- 363
Query: 411 SSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSK 470
++ G+ S+ SP + A PPS P +PP S
Sbjct: 364 --QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA 421
Query: 471 EPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFST 530
PS AP A V S PS V P +PP+SP S S + A PP +
Sbjct: 422 TPSPQAPN-ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA----PPSLAA 476
Query: 531 APEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSE 590
P P P +S M+ A P P APP A PPLQL++
Sbjct: 477 PPLQVPPSPPAS-PPMSPSAT-------PPP--------------QAPPPLAAPPLQLAK 514
Query: 591 --VNIPLSLGVCPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPY 648
P +L PL +P QA PS S LP +P TPP
Sbjct: 515 PPPQAPPALATPPLQALPSPPASFPGQAPFS--------PSAS------LPMSPLATPP- 559
Query: 649 HHQMPP 654
Q PP
Sbjct: 560 -PQAPP 564
Score = 63.2 bits (152), Expect = 9e-10
Identities = 89/353 (25%), Positives = 120/353 (33%), Gaps = 61/353 (17%)
Query: 235 PQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDS 294
P SPP+ + S + P+ +PPSP
Sbjct: 446 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP-------------------- 485
Query: 295 EVSQSPAKNGSKPVHSNQHPQSP---AVPPTYPSGPPPAASALSTTPGNNGVPAPAA--- 348
PA P + PQ+P A PP + PPP A TP +P+P A
Sbjct: 486 -----PASPPMSP-SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP 539
Query: 349 -----PPSA---LGPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQP-RPPSVQPSGGG 399
PSA + P A+P P AP Q V P P+ P+ P RPP+ P
Sbjct: 540 GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ-VPPSPPASPTLQAPRRPPTPGPDTSV 598
Query: 400 GG-------GSGGGGSSSSSNSSAGGG---AGKQNGATSYSSVVA--DSPAEVALSSSGG 447
G G S S SS G AG + ATS + DS E ++S
Sbjct: 599 SGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 658
Query: 448 NNASSQALGPPSGPHNPPPSTSKEPSAAAP-TGAGGVAPGSGN------NSGGPSLLVPL 500
+A A P + P P + + AP PGS + + GP P
Sbjct: 659 PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPA 718
Query: 501 PVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAERAAIS 553
P P+P S KAA G S PL +L++ + +S
Sbjct: 719 PGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLS 771
Score = 60.8 bits (146), Expect = 4e-09
Identities = 111/481 (23%), Positives = 151/481 (31%), Gaps = 128/481 (26%)
Query: 262 TSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQS-PAVP 320
T SP PP P R V + P + + P+S P
Sbjct: 26 TPRPPGSPRPPPPVTPAA-------LRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAG 78
Query: 321 PTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQA------ 374
PT +G A G AP A ++ GP +SP + + P P Q
Sbjct: 79 PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 138
Query: 375 -------------------------VAPPAPSGPS---------------------TTQP 388
+ P P PS + +P
Sbjct: 139 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 198
Query: 389 RPPSVQPSGGGGGGSGGGGSSSS----SNSSAGGGAGK-QNGATSYSSVVADSPAEVALS 443
RPP+ P S + S SAGGG + + + S S+ SPA S
Sbjct: 199 RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS 258
Query: 444 SSGGNNASS----------QALGPPS------------GPHNPPPSTSKEPSAAAPTGAG 481
+ G A + QAL PP GP + P + PSAA + A
Sbjct: 259 ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAP 318
Query: 482 GVAPGSGNNSG-GPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPL 540
P + ++S L PLP+ PPS + PP T P A P
Sbjct: 319 PTLPATPHSSSLTCQLATPLPLAPPSP---------------SAPPSLQTLPSPPATPPS 363
Query: 541 SSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVC 600
+ S+ ++ P P L + APPA A PPLQ + + P S +
Sbjct: 364 QATTSLGSPTLQATHSFLPSPPL----SPLATPPPQAPPALALPPLQ-APPSPPASPPLS 418
Query: 601 PLG-PVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDT 659
PL P P QA A H + P +P P+PP PP S
Sbjct: 419 PLATPSP--------QAPNALAVHLL-----------QAPFSPPPSPPVQAPFSPPASPP 459
Query: 660 V 660
V
Sbjct: 460 V 460
Score = 54.3 bits (129), Expect = 4e-07
Identities = 79/326 (24%), Positives = 112/326 (34%), Gaps = 44/326 (13%)
Query: 258 SSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSP 317
S+ P+ T SP P+ TT + +T S + P + P PQ+P
Sbjct: 346 SAPPSLQTLPSPPATPPSQATTSLGSPTLQ---ATHSFLPSPPLSPLATPP-----PQAP 397
Query: 318 AV--------PPTYPSGPPPAASALSTTPGNNG-----VPAPAAPP------SALGPKAS 358
PP+ P+ PP + A + N + AP +PP + P AS
Sbjct: 398 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 457
Query: 359 PAPSHNSGTPAPYAQAVAPP---APSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSS 415
P S ++ P+ ++A P P P + P PS P +
Sbjct: 458 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 517
Query: 416 AGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPH-------NPPPST 468
A + S A P + S S S A PP P PPS
Sbjct: 518 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 577
Query: 469 SKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQF 528
P+ AP PG + GP L + L PP P+ S S + +G L G
Sbjct: 578 PASPTLQAPRRP--PTPGPDTSVSGPRLTLALAPGPPPPPSRSPS-STLSGPDLAGHSSS 634
Query: 529 STAPEIKAPEPLSSLKSMAERAAISS 554
+T+ PE L S E A +S
Sbjct: 635 ATS----TPEELRGYDSGPEGGAAAS 656
Score = 49.3 bits (116), Expect = 1e-05
Identities = 64/254 (25%), Positives = 90/254 (35%), Gaps = 29/254 (11%)
Query: 234 IPQALVATSPPSHSH-MEDEIFNQSSSTPTSTTSSSPI-PPSPANCTTENSED-DKKRGR 290
+P + +AT PP + + S P S T +P PP+P T+ +
Sbjct: 550 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 609
Query: 291 STDSEVSQSPAKNGSKPV---HSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPA 347
S+SP+ S P HS+ +P Y SGP A+A PA
Sbjct: 610 GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA 669
Query: 348 APPSALGPKASPAPSHNSGTPAPYAQAVAPPAPSG---------PSTTQPRP----PSVQ 394
A + GP A G P P+ A P + G P + P P P
Sbjct: 670 A--WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPS 727
Query: 395 PSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVAD--------SPAEVALSSSG 446
P GG + G G+ +SS S G+ +SVV + AE A SG
Sbjct: 728 PGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSG 787
Query: 447 GNNASSQALGPPSG 460
G ++ G G
Sbjct: 788 GGPGGAEGGGVTGG 801
Score = 35.8 bits (81), Expect = 0.15
Identities = 46/209 (22%), Positives = 71/209 (33%), Gaps = 26/209 (12%)
Query: 364 NSGTPAPYAQAVAPPAPSGPSTTQPRPPS-------VQPSGGGGGGSGGGGSSSSSNSSA 416
N A A PA P PRPP V P+ G+ G A
Sbjct: 3 NKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA 62
Query: 417 GGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSG--PHNPPPSTSKEPSA 474
GG G + + +S + S G ++ + A PP+ PP+ + P
Sbjct: 63 GGIGG---------ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGP 113
Query: 475 AAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSS-PTPSFSDAKAAGALLNGPPQFSTAPE 533
+ G SG GP L ++ + ++A AL G + ++ P
Sbjct: 114 VSSPGR-----ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT 168
Query: 534 IKAPEPLSSLKSMAERAAISSGIEDPVPT 562
P P + +S A A G+ P P+
Sbjct: 169 PGTPSPAMARRSRA--AGTEVGLPRPAPS 195
Score = 31.6 bits (70), Expect = 2.8
Identities = 48/197 (24%), Positives = 62/197 (31%), Gaps = 44/197 (22%)
Query: 258 SSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSE---VSQSPAKNGSKPVHSNQHP 314
S +P+ST S P + ++ S ++ RG + E + P H
Sbjct: 616 SRSPSSTLSG---PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS 672
Query: 315 QSPAVPPTYPSGP------PPA-----ASALSTTPGNNGVPAPAAPPSALGPKASPAPSH 363
+ PA P + P PPA A L T G + P AL P SP
Sbjct: 673 RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP---- 728
Query: 364 NSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGG--------------------GGGGS 403
GT A A A S S Q R + P G G G
Sbjct: 729 --GTSGGKAAAGAGAGASSRSPKQARLGEL-PLGALQASVVQHLLSRTLLLAAAEGAAGG 785
Query: 404 GGGGSSSSSNSSAGGGA 420
GGG + GGA
Sbjct: 786 SGGGPGGAEGGGVTGGA 802
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 75.1 bits (183), Expect = 2e-13
Identities = 87/322 (27%), Positives = 106/322 (32%), Gaps = 40/322 (12%)
Query: 225 LYDDLDLEDIPQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSED 284
L +D+ E+ P +L+A +P S N+ P PP N
Sbjct: 19 LNEDVSQEESP-SLIAGNPQGPSPQGG---NKPQGPPPPPGKPQGPPPQGGNKPQGPPPP 74
Query: 285 DKKRGRSTDSEVSQSPAKNGSKPV----HSNQHPQSPAVPPTYPSGPPPAASALSTTPGN 340
K +G + S+SP KP PQ P PP P GPPP P
Sbjct: 75 GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPP 134
Query: 341 NGVP-----------APAAPPSALGPKASPAPSHN--SGTPAPYAQAVAPPAPSGPSTTQ 387
G P +P +PP P+ P N G P P + PP G
Sbjct: 135 PGKPQGPPPQGDKSRSPRSPPGK--PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQG 192
Query: 388 PRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGG 447
P PP G G G S SS S G G + P + G
Sbjct: 193 PPPP-----GKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 247
Query: 448 NNASSQALGPPSGPHNPP-PSTSKEPSAAAPTG-AGGVAPGSGNNSGGPSLLVPLPVNPP 505
N Q PP P PP SK SA +P G G GNN GP PP
Sbjct: 248 GN-KPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPP--------PP 298
Query: 506 SSPTPSFSDAKAAGALLNGPPQ 527
+ P A AG GPP+
Sbjct: 299 AGGNPQQPQAPPAGQ-PQGPPR 319
Score = 67.0 bits (162), Expect = 6e-11
Identities = 64/224 (28%), Positives = 71/224 (31%), Gaps = 21/224 (9%)
Query: 255 NQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPV----HS 310
NQ P PP N K +G + S+SP KP
Sbjct: 106 NQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 165
Query: 311 NQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAP 370
PQ P PP P GPPP P G P PP ++S +P P P
Sbjct: 166 GNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKP-QGPPPQGDKSRSSQSPPGKPQGPPP 224
Query: 371 YA--QAVAPPAPSGPSTTQP-----RPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQ 423
Q PP P G P +P P G G GGS S SA GK
Sbjct: 225 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKS---QSARSPPGKP 281
Query: 424 NGATSYSSVVADSPAEVALSSSGGNNASSQA--LGPPSGPHNPP 465
G P A GGN QA G P GP PP
Sbjct: 282 QGPPQQEGNNPQGPPPPA----GGNPQQPQAPPAGQPQGPPRPP 321
Score = 62.4 bits (150), Expect = 2e-09
Identities = 66/265 (24%), Positives = 82/265 (30%), Gaps = 45/265 (16%)
Query: 278 TTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTT 337
+ +N +D + S S ++ +P G P N+ PQ P PP P GPPP
Sbjct: 15 SAQNLNEDVSQEESP-SLIAGNP--QGPSPQGGNK-PQGPPPPPGKPQGPPPQG------ 64
Query: 338 PGNNGVPAPAAPPSALGPKASPAPSHNSGTP-APYAQAVAPPAPSGPSTTQPRPPSVQPS 396
GN P PP P+ P S +P +P + PP G P PP +P
Sbjct: 65 -GNK----PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 119
Query: 397 GGG--GGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQA 454
G GG G K S P + G N
Sbjct: 120 GPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQ-------GGNQPQGP 172
Query: 455 LGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSD 514
PP P PPP K+P P G P PP S S
Sbjct: 173 PPPPGKPQGPPPQGGKKPQGPPPPGK--------------------PQGPPPQGDKSRSS 212
Query: 515 AKAAGALLNGPPQFSTAPEIKAPEP 539
G PPQ P+ P P
Sbjct: 213 QSPPGKPQGPPPQGGNQPQGPPPPP 237
Score = 57.4 bits (137), Expect = 5e-08
Identities = 46/141 (32%), Positives = 53/141 (37%), Gaps = 15/141 (10%)
Query: 271 PPSPANCTTENSEDDKKRGRSTDSEVSQSP-AKNGSKPVHSNQHPQSPAVPPTYPSGPPP 329
PP P + DK R SQSP K P PQ P PP P GPPP
Sbjct: 193 PPPPGKPQGPPPQGDKSRS-------SQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 245
Query: 330 AASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQA----VAPPAPSGPST 385
P G P PP+ G K+ A S P Q PP P+G +
Sbjct: 246 QGGNKPQGPPPPG--KPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNP 303
Query: 386 TQPR-PPSVQPSGGGGGGSGG 405
QP+ PP+ QP G GG
Sbjct: 304 QQPQAPPAGQPQGPPRPPQGG 324
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 73.6 bits (179), Expect = 7e-13
Identities = 110/401 (27%), Positives = 141/401 (35%), Gaps = 84/401 (20%)
Query: 262 TSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPP 321
+S + S PSPA ++ +R S S +P S P S + P
Sbjct: 201 SSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL---SSPARSGPSARGTPRAP 257
Query: 322 TYPSGPPP----AASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAP 377
+PS P P A TP APA P + P A+P+PS AP
Sbjct: 258 AHPSQPKPKGLQALRPPQVTPPRKDA-APALGPLSSSPLATPSPS-------------AP 303
Query: 378 PAPSGPSTTQ--PRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVAD 435
P+PS P + Q P PP+ PS ++ G+ S+
Sbjct: 304 PSPSAPPSLQTLPSPPATPPS----------------QATTSLGSPTLQATHSFLPSPPL 347
Query: 436 SPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPGSGNNSGGPS 495
SP + A PPS P +PP S PS AP A V S PS
Sbjct: 348 SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPN-ALAVHLLQAPFSPPPS 406
Query: 496 LLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAERAAISSG 555
V P +PP+SP S S + A PP + P P P +S M+ A
Sbjct: 407 PPVQAPFSPPASPPVSPSATPPSQA----PPSLAAPPLQVPPSPPAS-PPMSPSAT---- 457
Query: 556 IEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSE--VNIPLSLGVCPLGPVPLTKEQLY 613
P P APP A PPLQL++ P +L PL +P
Sbjct: 458 ---PPP--------------QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP 500
Query: 614 QQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPP 654
QA PS S LP +P TPP Q PP
Sbjct: 501 GQAPFS--------PSAS------LPMSPLATPP--PQAPP 525
Score = 70.5 bits (171), Expect = 6e-12
Identities = 107/433 (24%), Positives = 143/433 (33%), Gaps = 71/433 (16%)
Query: 262 TSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQS-PAVP 320
T SP PP P R V + P + + P+S P
Sbjct: 26 TPRPPGSPRPPPPVTPAA-------LRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAG 78
Query: 321 PTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSG-------------- 366
PT S PP + P N P P + P P P G
Sbjct: 79 PTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA 138
Query: 367 TPAPYAQAVAPPA---PSGPSTTQPRPPSVQPSGGGGGGSG-GGGSSSSSNSSAGGGAGK 422
T AP A++ A SGP+ P P + S G G + S+ G K
Sbjct: 139 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK 198
Query: 423 QNGATSYSSVVADSPAEVALSSSGG------NNASSQALGPPSGPHNPPPSTSKEPSAAA 476
+ S S SPA S+GG + + S + P S P PS P A A
Sbjct: 199 SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA 258
Query: 477 ------PTGAGGVAPG--SGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQF 528
P G + P + L PL +P ++P+PS + +A PP
Sbjct: 259 HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSA------PPSL 312
Query: 529 STAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQL 588
T P A P + S+ ++ P P L + APPA A PPLQ
Sbjct: 313 QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL----SPLATPPPQAPPALALPPLQ- 367
Query: 589 SEVNIPLSLGVCPLG-PVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPP 647
+ + P S + PL P P QA A H + P +P P+PP
Sbjct: 368 APPSPPASPPLSPLATPSP--------QAPNALAVHLL-----------QAPFSPPPSPP 408
Query: 648 YHHQMPPPHSDTV 660
PP S V
Sbjct: 409 VQAPFSPPASPPV 421
Score = 62.4 bits (150), Expect = 2e-09
Identities = 75/318 (23%), Positives = 119/318 (37%), Gaps = 22/318 (6%)
Query: 242 SPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPA 301
+PPS + ++ ++P + S++P P +P + K ++ + +
Sbjct: 431 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQ 490
Query: 302 KNGSKPVH-SNQHPQSPA--VPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKAS 358
S P Q P SP+ +P + + PPP A + P P+P A P+ P+
Sbjct: 491 ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP 550
Query: 359 PAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSS--- 415
P P ++ P P P P PS PS G G SSS++++
Sbjct: 551 PTPGPDTSVSGPRLTLALAPGPPPP-------PSRSPSSTLSGPDLAGHSSSATSTPEEL 603
Query: 416 AGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAA 475
G +G + GA A SP A ++ A S+ PP P + P A
Sbjct: 604 RGYDSGPEGGA-------AASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT 656
Query: 476 APTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIK 535
P A G+ + + GP P P P+P S KAA G S
Sbjct: 657 GPGSADGLC--TIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARL 714
Query: 536 APEPLSSLKSMAERAAIS 553
PL +L++ + +S
Sbjct: 715 GELPLGALQASVVQHLLS 732
Score = 55.8 bits (133), Expect = 1e-07
Identities = 86/360 (23%), Positives = 125/360 (34%), Gaps = 47/360 (13%)
Query: 235 PQALVATSPPSHSHMEDEI---FNQSSSTPTSTTSSS--PIPPSPANCTTENSEDDKKRG 289
P+ L A PP + + SS+P +T S S P P +P + T S
Sbjct: 265 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPS 324
Query: 290 RSTDS------EVSQSPAKNGSKPVHSNQHPQSPAV--------PPTYPSGPPPAASALS 335
++T S + + S + + PQ+P PP+ P+ PP + A
Sbjct: 325 QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 384
Query: 336 TTPGNNG-----VPAPAAPP------SALGPKASPAPSHNSGTPAPYAQAVAPP---APS 381
+ N + AP +PP + P ASP S ++ P+ ++A P P
Sbjct: 385 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP 444
Query: 382 GPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVA 441
P + P PS P + A + S A P +
Sbjct: 445 SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 504
Query: 442 LSSSGGNNASSQALGPPSGPH-------NPPPSTSKEPSAAAPTGAGGVAPGSGNNSGGP 494
S S S A PP P PPS P+ AP PG + GP
Sbjct: 505 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP--PTPGPDTSVSGP 562
Query: 495 SLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAERAAISS 554
L + L PP P+ S S + +G L G +T+ PE L S E A +S
Sbjct: 563 RLTLALAPGPPPPPSRSPS-STLSGPDLAGHSSSATS----TPEELRGYDSGPEGGAAAS 617
Score = 49.3 bits (116), Expect = 1e-05
Identities = 64/254 (25%), Positives = 90/254 (35%), Gaps = 29/254 (11%)
Query: 234 IPQALVATSPPSHSH-MEDEIFNQSSSTPTSTTSSSPI-PPSPANCTTENSED-DKKRGR 290
+P + +AT PP + + S P S T +P PP+P T+ +
Sbjct: 511 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 570
Query: 291 STDSEVSQSPAKNGSKPV---HSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPA 347
S+SP+ S P HS+ +P Y SGP A+A PA
Sbjct: 571 GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA 630
Query: 348 APPSALGPKASPAPSHNSGTPAPYAQAVAPPAPSG---------PSTTQPRP----PSVQ 394
A + GP A G P P+ A P + G P + P P P
Sbjct: 631 A--WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPS 688
Query: 395 PSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVAD--------SPAEVALSSSG 446
P GG + G G+ +SS S G+ +SVV + AE A SG
Sbjct: 689 PGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSG 748
Query: 447 GNNASSQALGPPSG 460
G ++ G G
Sbjct: 749 GGPGGAEGGGVTGG 762
Score = 33.5 bits (75), Expect = 0.75
Identities = 91/385 (23%), Positives = 117/385 (30%), Gaps = 122/385 (31%)
Query: 364 NSGTPAPYAQAVAPPAPSGPSTTQPRPPS-------VQPS-----GGGG----------- 400
N A A PA P PRPP V P+ G G
Sbjct: 3 NKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA 62
Query: 401 GGSGG---------GGSSSSSNSSAGG-----------------GAGKQNGAT------- 427
GG GG G + +S A G G+ +G T
Sbjct: 63 GGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 122
Query: 428 -----SYSSVVA-----DSPAEVALSSSGGNNASSQALGPPS--------------GPHN 463
S VA ++P ALS+ + S G PS G
Sbjct: 123 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 182
Query: 464 PPPSTSKEPSAAAPTGAGGVAPGSGNN----------SGGPSLLVPLPVNPPSSPTPSFS 513
P PS P P + A S G L P + SS TP S
Sbjct: 183 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 242
Query: 514 DAKAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTL-HLTERDIIL 572
A+ +G G P+ P P+ L +L+ ++ +D P L L+ +
Sbjct: 243 PAR-SGPSARGTPRAPAHPSQPKPKGLQALRP----PQVTPPRKDAAPALGPLSSSPLAT 297
Query: 573 SSTSAPPA-SAQPPLQL--SEVNIPLSLGVCPLGPVPLTKEQLYQQAMEEAAWHHMPHPS 629
S SAPP+ SA P LQ S P S LG L +A +P P
Sbjct: 298 PSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL-----------QATHSFLPSP- 345
Query: 630 DSERIRQYLPRNPCPTPPYHHQMPP 654
P +P TPP Q PP
Sbjct: 346 ---------PLSPLATPP--PQAPP 359
Score = 31.6 bits (70), Expect = 2.8
Identities = 48/197 (24%), Positives = 62/197 (31%), Gaps = 44/197 (22%)
Query: 258 SSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSE---VSQSPAKNGSKPVHSNQHP 314
S +P+ST S P + ++ S ++ RG + E + P H
Sbjct: 577 SRSPSSTLSG---PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS 633
Query: 315 QSPAVPPTYPSGP------PPA-----ASALSTTPGNNGVPAPAAPPSALGPKASPAPSH 363
+ PA P + P PPA A L T G + P AL P SP
Sbjct: 634 RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP---- 689
Query: 364 NSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGG--------------------GGGGS 403
GT A A A S S Q R + P G G G
Sbjct: 690 --GTSGGKAAAGAGAGASSRSPKQARLGEL-PLGALQASVVQHLLSRTLLLAAAEGAAGG 746
Query: 404 GGGGSSSSSNSSAGGGA 420
GGG + GGA
Sbjct: 747 SGGGPGGAEGGGVTGGA 763
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 71.2 bits (173), Expect = 3e-12
Identities = 77/277 (27%), Positives = 101/277 (36%), Gaps = 48/277 (17%)
Query: 291 STDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASAL-----------STTPG 339
ST + SP GS PV P+ P+ PT P P +AL S++P
Sbjct: 189 STPRPIQSSPHNRGSPPVPGG--PRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPF 246
Query: 340 NNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPAPSG-----PSTTQPR----- 389
+N P P P AL K P P P+ + +AV PP P PST +P
Sbjct: 247 SNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQA 306
Query: 390 -PPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGN 448
PP PS G SSS + ++N + S S+ SP
Sbjct: 307 PPPPPPPSRPGPPPL----PPSSSGNDETPRLPQRNLSLSSSTPPLPSPGR--------- 353
Query: 449 NASSQALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSP 508
SGP PPPS P P G G P S S LP P P
Sbjct: 354 ----------SGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPAT-PQLP 402
Query: 509 TPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKS 545
+ S D+ +G PP +A P P +S+++
Sbjct: 403 SRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRN 439
Score = 57.8 bits (138), Expect = 4e-08
Identities = 73/312 (23%), Positives = 96/312 (30%), Gaps = 76/312 (24%)
Query: 338 PGNNGVPA-PAAPPSALGPKASPAPSHNSGTPAPY--------------AQAVAPPAPSG 382
PG A P +PPS G P+P H SG P P ++ PP PS
Sbjct: 131 PGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPST 190
Query: 383 PSTTQ--------------PRPPSVQPS-----GGGGGGSGGGGSSSSSNSSAGGGAGKQ 423
P Q PR PS P+ G G GGG S SS+ + +
Sbjct: 191 PRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRP 250
Query: 424 NGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPP--------STSKEPSAA 475
+ S + D P + +A+ PP +N PP ++S+ P
Sbjct: 251 PLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPP 310
Query: 476 APTGAGGVAPGSGNNSG----------------------GPSLLVPLPVNPPSSPTPSFS 513
P G P ++SG P PLP P P P
Sbjct: 311 PPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVR 370
Query: 514 DAKAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILS 573
D L PP S L + + R+ + S P P L
Sbjct: 371 DPPGRSGPLPPPPPVSR--NGSTSRALPATPQLPSRSGVDSPRSGPRPPL---------- 418
Query: 574 STSAPPASAQPP 585
P A A PP
Sbjct: 419 PPDRPSAGAPPP 430
Score = 52.4 bits (124), Expect = 2e-06
Identities = 86/355 (24%), Positives = 118/355 (33%), Gaps = 52/355 (14%)
Query: 317 PAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVA 376
P PP P+ PPP AL+ T A +AL S +
Sbjct: 2 PVPPP--PAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKK---------LKKTV 50
Query: 377 PPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVV-AD 435
S P +P+ +GGGGGG GGGG GGG+ G + A
Sbjct: 51 TNDRSAPILDKPKGAG---AGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAG 107
Query: 436 SP--------------AEVALSSSGGNNASSQALGPPSGPHN-PPPSTSKEPSAAAPTGA 480
P + L GG + S++ PPSGP P PS P
Sbjct: 108 MPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRN 167
Query: 481 GGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPL 540
P S S+ P+P P P S + + + GP Q S P P P
Sbjct: 168 RMPPPRPDVGSKPDSIPPPVPSTP--RPIQSSPHNRGSPPVPGGPRQPSPGP---TPPPF 222
Query: 541 SSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVC 600
+ A+ G + R LSS+S P S +PPL +
Sbjct: 223 PGNRG----TALGGG----------SIRQSPLSSSS--PFSNRPPLPPTPSRALDDKPPP 266
Query: 601 PLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPP 655
P PV + ++++A+ + P S + P P PP PPP
Sbjct: 267 PPPPVG-NRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPP 320
Score = 45.4 bits (106), Expect = 2e-04
Identities = 35/131 (26%), Positives = 49/131 (37%), Gaps = 11/131 (8%)
Query: 261 PTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVP 320
P S P+PPS + + S+ + SP ++G P ++ P P
Sbjct: 312 PPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRD 371
Query: 321 PTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPAP 380
P SGP P +S NG + A P A+P SG +P + P P
Sbjct: 372 PPGRSGPLPPPPPVS----RNGSTSRALP-------ATPQLPSRSGVDSPRSGPRPPLPP 420
Query: 381 SGPSTTQPRPP 391
PS P PP
Sbjct: 421 DRPSAGAPPPP 431
Score = 30.4 bits (67), Expect = 6.3
Identities = 33/124 (26%), Positives = 42/124 (33%), Gaps = 22/124 (17%)
Query: 243 PPSHS------HMEDEIFNQSSSTPT--STTSSSPIPPSPANCTTENSEDDK-------- 286
PPS S + + SSSTP S S P+PP P+ D
Sbjct: 322 PPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP 381
Query: 287 ----KRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPS--GPPPAASALSTTPGN 340
R ST + +P V S + P +PP PS PPP + S G
Sbjct: 382 PPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGF 441
Query: 341 NGVP 344
P
Sbjct: 442 QDSP 445
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 71.2 bits (173), Expect = 3e-12
Identities = 77/277 (27%), Positives = 101/277 (36%), Gaps = 48/277 (17%)
Query: 291 STDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASAL-----------STTPG 339
ST + SP GS PV P+ P+ PT P P +AL S++P
Sbjct: 189 STPRPIQSSPHNRGSPPVPGG--PRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPF 246
Query: 340 NNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPAPSG-----PSTTQPR----- 389
+N P P P AL K P P P+ + +AV PP P PST +P
Sbjct: 247 SNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQA 306
Query: 390 -PPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGN 448
PP PS G SSS + ++N + S S+ SP
Sbjct: 307 PPPPPPPSRPGPPPL----PPSSSGNDETPRLPQRNLSLSSSTPPLPSPGR--------- 353
Query: 449 NASSQALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSP 508
SGP PPPS P P G G P S S LP P P
Sbjct: 354 ----------SGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPAT-PQLP 402
Query: 509 TPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKS 545
+ S D+ +G PP +A P P +S+++
Sbjct: 403 SRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRN 439
Score = 57.8 bits (138), Expect = 4e-08
Identities = 73/312 (23%), Positives = 96/312 (30%), Gaps = 76/312 (24%)
Query: 338 PGNNGVPA-PAAPPSALGPKASPAPSHNSGTPAPY--------------AQAVAPPAPSG 382
PG A P +PPS G P+P H SG P P ++ PP PS
Sbjct: 131 PGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPST 190
Query: 383 PSTTQ--------------PRPPSVQPS-----GGGGGGSGGGGSSSSSNSSAGGGAGKQ 423
P Q PR PS P+ G G GGG S SS+ + +
Sbjct: 191 PRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRP 250
Query: 424 NGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPP--------STSKEPSAA 475
+ S + D P + +A+ PP +N PP ++S+ P
Sbjct: 251 PLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPP 310
Query: 476 APTGAGGVAPGSGNNSG----------------------GPSLLVPLPVNPPSSPTPSFS 513
P G P ++SG P PLP P P P
Sbjct: 311 PPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVR 370
Query: 514 DAKAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILS 573
D L PP S L + + R+ + S P P L
Sbjct: 371 DPPGRSGPLPPPPPVSR--NGSTSRALPATPQLPSRSGVDSPRSGPRPPL---------- 418
Query: 574 STSAPPASAQPP 585
P A A PP
Sbjct: 419 PPDRPSAGAPPP 430
Score = 52.4 bits (124), Expect = 2e-06
Identities = 86/355 (24%), Positives = 118/355 (33%), Gaps = 52/355 (14%)
Query: 317 PAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVA 376
P PP P+ PPP AL+ T A +AL S +
Sbjct: 2 PVPPP--PAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKK---------LKKTV 50
Query: 377 PPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVV-AD 435
S P +P+ +GGGGGG GGGG GGG+ G + A
Sbjct: 51 TNDRSAPILDKPKGAG---AGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAG 107
Query: 436 SP--------------AEVALSSSGGNNASSQALGPPSGPHN-PPPSTSKEPSAAAPTGA 480
P + L GG + S++ PPSGP P PS P
Sbjct: 108 MPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRN 167
Query: 481 GGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPL 540
P S S+ P+P P P S + + + GP Q S P P P
Sbjct: 168 RMPPPRPDVGSKPDSIPPPVPSTP--RPIQSSPHNRGSPPVPGGPRQPSPGP---TPPPF 222
Query: 541 SSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVC 600
+ A+ G + R LSS+S P S +PPL +
Sbjct: 223 PGNRG----TALGGG----------SIRQSPLSSSS--PFSNRPPLPPTPSRALDDKPPP 266
Query: 601 PLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPP 655
P PV + ++++A+ + P S + P P PP PPP
Sbjct: 267 PPPPVG-NRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPP 320
Score = 45.4 bits (106), Expect = 2e-04
Identities = 35/131 (26%), Positives = 49/131 (37%), Gaps = 11/131 (8%)
Query: 261 PTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVP 320
P S P+PPS + + S+ + SP ++G P ++ P P
Sbjct: 312 PPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRD 371
Query: 321 PTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPAP 380
P SGP P +S NG + A P A+P SG +P + P P
Sbjct: 372 PPGRSGPLPPPPPVS----RNGSTSRALP-------ATPQLPSRSGVDSPRSGPRPPLPP 420
Query: 381 SGPSTTQPRPP 391
PS P PP
Sbjct: 421 DRPSAGAPPPP 431
Score = 30.4 bits (67), Expect = 6.3
Identities = 33/124 (26%), Positives = 42/124 (33%), Gaps = 22/124 (17%)
Query: 243 PPSHS------HMEDEIFNQSSSTPT--STTSSSPIPPSPANCTTENSEDDK-------- 286
PPS S + + SSSTP S S P+PP P+ D
Sbjct: 322 PPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP 381
Query: 287 ----KRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPS--GPPPAASALSTTPGN 340
R ST + +P V S + P +PP PS PPP + S G
Sbjct: 382 PPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGF 441
Query: 341 NGVP 344
P
Sbjct: 442 QDSP 445
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 70.9 bits (172), Expect = 4e-12
Identities = 103/416 (24%), Positives = 140/416 (33%), Gaps = 50/416 (12%)
Query: 261 PTSTTSSSPIPPS----PANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQS 316
P T SS PPS PA+ TT E+ ++ P + S P+ + H ++
Sbjct: 510 PPLETQSSLAPPSLQTPPASLTTPPLENLPS--------LAPPPLQTASAPL-TTPHLET 560
Query: 317 PAVPPTYPSGPPPAASALST----TPGNNGVPAPAAPPSALGPKASPAPS---HNSGTPA 369
P P P PP S L+T TP + P P APP+ P PS TP
Sbjct: 561 PPCPAPCPLQAPP--SPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPP 618
Query: 370 PYAQA--VAPP--APSGPSTTQPRPPSVQPSGGGGGGSG----GGGSSSSSNSSAGGGAG 421
P A PP AP P + P P PS S +
Sbjct: 619 PQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 678
Query: 422 KQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGAG 481
S S A +L++ S PP P PP + P AA P
Sbjct: 679 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVP 738
Query: 482 GVAPGSGNNSGG-------PSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEI 534
P S S P LL P+ P SP S + A PP +T P
Sbjct: 739 PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQ 798
Query: 535 KAPEPLSSLKSMA----ERAAISSGIEDPVPTLHLTERDIILSSTSAPPAS------AQP 584
P P +S A + S + P P +L +PPAS +P
Sbjct: 799 ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP 858
Query: 585 PLQLSEVNIP---LSLGVCPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQY 637
P + ++ L+L + P P P ++ + + A H S E +R Y
Sbjct: 859 PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 914
Score = 62.0 bits (149), Expect = 2e-09
Identities = 79/326 (24%), Positives = 114/326 (34%), Gaps = 25/326 (7%)
Query: 235 PQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDS 294
P V SPP+ M P +PPSP + K
Sbjct: 733 PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPL--AKPPPQAPP 790
Query: 295 EVSQSPAKNGSKPVHS--NQHPQSPA--VPPTYPSGPPPAASALSTTPGNNGVPAPAAPP 350
++ P + P S Q P SP+ +P + + PPP A + P P+P A P
Sbjct: 791 ALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 850
Query: 351 SALGPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSS 410
+ P+ P P ++ P P P P PS PS G G SSS
Sbjct: 851 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP-------PSRSPSSTLSGPDLAGHSSS 903
Query: 411 SSNSS---AGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPS 467
++++ G +G + GA A SP A ++ A S+ PP P +
Sbjct: 904 ATSTPEELRGYDSGPEGGA-------AASPPPDAELAACHPAAWSRGPAPPLAFRGAPGA 956
Query: 468 TSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQ 527
P A P A G+ + + GP P P P+P S KAA G
Sbjct: 957 PLPWPPATGPGSADGLC--TIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASS 1014
Query: 528 FSTAPEIKAPEPLSSLKSMAERAAIS 553
S PL +L++ + +S
Sbjct: 1015 RSPKQARLGELPLGALQASVVQHLLS 1040
Score = 57.4 bits (137), Expect = 5e-08
Identities = 109/465 (23%), Positives = 151/465 (32%), Gaps = 84/465 (18%)
Query: 257 SSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQS 316
SS+TP S+ + S + K +G +P + + P S
Sbjct: 244 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA-LGPLSSS 302
Query: 317 PAVPPTYPSGP-----PPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPY 371
P P+ PSG PP +A + P P A P L P + AP P+P
Sbjct: 303 PLATPS-PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPP 361
Query: 372 AQAVAPPAPSGPSTTQP---RPPSVQP--------SGGGGGGSGGGGSSSSSNSSAGGGA 420
A PP+ + PS T P PPS+Q S + S+ A
Sbjct: 362 A---TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL 418
Query: 421 GKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPP-----SGPHNPPPSTSKEPSAA 475
G ++S + A +S AS+ PP S P +PP TS P+ +
Sbjct: 419 GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVS 478
Query: 476 APTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIK 535
+ + P +S L + P +P S PP T P
Sbjct: 479 PLSSPLTIHPLQALSS--------LASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASL 530
Query: 536 APEPLSSLKSMAERAAISSGIEDPVPTLHL------------------------TERDII 571
PL +L S+A ++ P+ T HL T I
Sbjct: 531 TTPPLENLPSLAPPPLQTASA--PLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIA 588
Query: 572 LSSTSAPPASAQPPLQ------LSEVNIP-------LSLGVCPLGPVPLTKEQLYQQAME 618
APPA A PPLQ LS + P L+L P P L A
Sbjct: 589 TPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLA-- 646
Query: 619 EAAWHHMPHPSDSERIRQYL---PRNPCPTPPYHHQMPPPHSDTV 660
P P + +L P +P P+PP PP S V
Sbjct: 647 ------TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 685
Score = 55.8 bits (133), Expect = 1e-07
Identities = 118/513 (23%), Positives = 157/513 (30%), Gaps = 131/513 (25%)
Query: 262 TSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQS-PAVP 320
T SP PP P R V + P + + P+S P
Sbjct: 26 TPRPPGSPRPPPPVTPAA-------LRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAG 78
Query: 321 PTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQA------ 374
PT +G A G AP A ++ GP +SP + + P P Q
Sbjct: 79 PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 138
Query: 375 -------------------------VAPPAPSGPS---------------------TTQP 388
+ P P PS + +P
Sbjct: 139 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 198
Query: 389 RPPSVQPSGGGGGGSGGGGSSSS----SNSSAGGGAGK-QNGATSYSSVVADSPAEVALS 443
RPP+ P S + S SAGGG + + + S S+ SPA S
Sbjct: 199 RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS 258
Query: 444 SSGGNNASS----------QALGPPS------------GPHNPPPSTSKEPSAA----AP 477
+ G A + QAL PP GP + P + PS P
Sbjct: 259 ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVP 318
Query: 478 TGAGGVAPGSGNNSGGPSLLVPLPVNPPS-SPTPSFSDAKAAGAL-------------LN 523
P P L PLP+ PPS S PS + A +
Sbjct: 319 PPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQ 378
Query: 524 GPPQFSTAPEIKAPEPLSSLKSMAERAAIS-SGIEDPV----PTLHLTERDIILS----- 573
PP T P I+ P L+S A + ++ S ++ PTL T + +S
Sbjct: 379 APPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQ 438
Query: 574 -STSAPPASAQPPLQLSEVNIPLSLGVCP-----LGPV------PLTKEQLYQQAMEEAA 621
S ++P A P + PLSL P L P PLT L QA+ A
Sbjct: 439 ASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPL--QALSSLA 496
Query: 622 WHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPP 654
H P S I L PP Q PP
Sbjct: 497 -SHSPQAPLSSLIMPPLETQSSLAPP-SLQTPP 527
Score = 49.3 bits (116), Expect = 1e-05
Identities = 64/254 (25%), Positives = 90/254 (35%), Gaps = 29/254 (11%)
Query: 234 IPQALVATSPPSHSH-MEDEIFNQSSSTPTSTTSSSPI-PPSPANCTTENSED-DKKRGR 290
+P + +AT PP + + S P S T +P PP+P T+ +
Sbjct: 819 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 878
Query: 291 STDSEVSQSPAKNGSKPV---HSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPA 347
S+SP+ S P HS+ +P Y SGP A+A PA
Sbjct: 879 GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA 938
Query: 348 APPSALGPKASPAPSHNSGTPAPYAQAVAPPAPSG---------PSTTQPRP----PSVQ 394
A + GP A G P P+ A P + G P + P P P
Sbjct: 939 A--WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPS 996
Query: 395 PSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVAD--------SPAEVALSSSG 446
P GG + G G+ +SS S G+ +SVV + AE A SG
Sbjct: 997 PGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSG 1056
Query: 447 GNNASSQALGPPSG 460
G ++ G G
Sbjct: 1057 GGPGGAEGGGVTGG 1070
Score = 35.8 bits (81), Expect = 0.15
Identities = 46/209 (22%), Positives = 71/209 (33%), Gaps = 26/209 (12%)
Query: 364 NSGTPAPYAQAVAPPAPSGPSTTQPRPPS-------VQPSGGGGGGSGGGGSSSSSNSSA 416
N A A PA P PRPP V P+ G+ G A
Sbjct: 3 NKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA 62
Query: 417 GGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSG--PHNPPPSTSKEPSA 474
GG G + + +S + S G ++ + A PP+ PP+ + P
Sbjct: 63 GGIGG---------ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGP 113
Query: 475 AAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSS-PTPSFSDAKAAGALLNGPPQFSTAPE 533
+ G SG GP L ++ + ++A AL G + ++ P
Sbjct: 114 VSSPGR-----ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT 168
Query: 534 IKAPEPLSSLKSMAERAAISSGIEDPVPT 562
P P + +S A A G+ P P+
Sbjct: 169 PGTPSPAMARRSRA--AGTEVGLPRPAPS 195
Score = 31.6 bits (70), Expect = 2.8
Identities = 48/197 (24%), Positives = 62/197 (31%), Gaps = 44/197 (22%)
Query: 258 SSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSE---VSQSPAKNGSKPVHSNQHP 314
S +P+ST S P + ++ S ++ RG + E + P H
Sbjct: 885 SRSPSSTLSG---PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS 941
Query: 315 QSPAVPPTYPSGP------PPA-----ASALSTTPGNNGVPAPAAPPSALGPKASPAPSH 363
+ PA P + P PPA A L T G + P AL P SP
Sbjct: 942 RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP---- 997
Query: 364 NSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGG--------------------GGGGS 403
GT A A A S S Q R + P G G G
Sbjct: 998 --GTSGGKAAAGAGAGASSRSPKQARLGEL-PLGALQASVVQHLLSRTLLLAAAEGAAGG 1054
Query: 404 GGGGSSSSSNSSAGGGA 420
GGG + GGA
Sbjct: 1055 SGGGPGGAEGGGVTGGA 1071
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 70.1 bits (170), Expect = 7e-12
Identities = 105/447 (23%), Positives = 151/447 (33%), Gaps = 93/447 (20%)
Query: 257 SSSTPTSTTSSSPIPPSPANCTTENSEDDKK-------RGRSTDSEVSQSPAKNGSKPVH 309
SSS+ S +SSS IP S +N + ++ R +S S V K G++
Sbjct: 530 SSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEE 589
Query: 310 SNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPA 369
S++ P PP + TP P+P PP P P P
Sbjct: 590 SSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPP--------PPP------PP 635
Query: 370 PYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSY 429
P PP P P P P PS G S++ + A+ +
Sbjct: 636 P------PPPPPPPPPPPPLPSQSAPSAG----------SAAPMFVKYSTITRLQNASQH 679
Query: 430 SSVVADSPAEVALSSSGGNNASSQALGPPSG---PHNPPPSTSKEPSAAAPTGAGGVAPG 486
S + P + S + Q L PP+G P PPP SA A AP
Sbjct: 680 SGALFKPPTPPVMQS---QSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPS 736
Query: 487 SGNNSGGP------------SLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEI 534
S P + P P PP P P PPQ P +
Sbjct: 737 LPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPL-------------PPQAPPKPLV 783
Query: 535 KAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIP 594
P P +S K++A + P P + ++ ++ PP+ PP+ + +P
Sbjct: 784 TIPAP-TSTKTVAP-VVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLP 841
Query: 595 LSLGVC------PLGPVPLTKEQLYQQ--------AMEEAAWHHMP------HPSDSERI 634
C PL PVP +Q+ Q AME +P P +
Sbjct: 842 KQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAK 901
Query: 635 RQYLPRN-PCPTPPYHHQMPPPHSDTV 660
++ P + P P+P + PPP S V
Sbjct: 902 PKWQPSSIPVPSPDF--PPPPPESSLV 926
Score = 60.5 bits (145), Expect = 6e-09
Identities = 90/375 (24%), Positives = 134/375 (35%), Gaps = 61/375 (16%)
Query: 235 PQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSP-----------IPPSPANCTTENSE 283
P+ LV P+ + + Q++ PT T P IPPSP
Sbjct: 779 PKPLVTIPAPTSTKTVAPVVTQAAP-PTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPP 837
Query: 284 DDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGV 343
+ +S ++ SP PV S + PP P+ P + L P N
Sbjct: 838 PTLPKQQSFCAKPPPSPLS----PVPSVVKQIASQFPPP-PTPPAMESQPLKPVPAN--- 889
Query: 344 PAPAAPPSALG-----PKASPAPSHNSGTPAPYAQAVAPPAPSG--PSTTQPRPPSVQPS 396
AP +PP+ P + P PS + P P + V PP P P+ P PP+ P+
Sbjct: 890 VAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPT 949
Query: 397 GGGGGGSGGGGSSSSS------------NSSAGGGAGKQNGATSYSSVVADSPAEVALSS 444
G G S +SS NSS +G ++ SV DS
Sbjct: 950 PDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSV--DSLVSKFTPP 1007
Query: 445 SGGNNASSQALGPPSGPHNPP---------PSTSKE--PSAAAPTGAGG--------VAP 485
+ + S + L PP+ P P P ++ SA AP +G +P
Sbjct: 1008 AESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSP 1067
Query: 486 GSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLN-GPPQFSTAPEIKAPEPLSSLK 544
S ++ P LP+ P P + A++N P Q+S KAP P +
Sbjct: 1068 PSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKR 1127
Query: 545 SMAERAAISSGIEDP 559
+ + R + E P
Sbjct: 1128 NDSTRLTQAEISEQP 1142
Score = 50.4 bits (119), Expect = 6e-06
Identities = 107/454 (23%), Positives = 149/454 (32%), Gaps = 95/454 (20%)
Query: 243 PPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAK 302
PP+ M+ + P + P PP P T S + + + Q A
Sbjct: 686 PPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPP--PTPGSAMAQLKPAPCAPSLPQFSAP 743
Query: 303 NGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKAS-PAP 361
+H QH A PPT P PP +PAP P + P + PAP
Sbjct: 744 PPPLKIHQVQHITQVA-PPTPPPPPP--------------IPAPLPPQAPPKPLVTIPAP 788
Query: 362 SHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAG 421
+ ++ T AP APP P+ P + P+ S S +
Sbjct: 789 T-STKTVAPVVTQAAPPTPTPPVPPAKKQPAFPAS-----------YIPPSPPTPPVPVP 836
Query: 422 KQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGP---------------HNPPP 466
S P+ ++ S +SQ PP+ P PP
Sbjct: 837 PPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPP 896
Query: 467 STSKEPS---AAAPTGAGGVAPGSGNNS----GGPSLLVPLPVNPP---SSPTPSFSDAK 516
+ +P ++ P + P +S P VP P PP +SPTP S +
Sbjct: 897 AVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSP 956
Query: 517 AAGALLNGPPQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTS 576
P P P+ SS+KS SSG E P P D ++S +
Sbjct: 957 GKKTSKTSSPGGKKPP--PTPQRNSSIKS-------SSGAEHPEP--KRPSVDSLVSKFT 1005
Query: 577 AP-----------PASAQPP----LQLSEVNIPLSLGVCPLGPVPLTKEQLYQQAMEEAA 621
P P A PP L LS VN+P GV G V L + +
Sbjct: 1006 PPAESGSPSKETLPPPAAPPKPGKLNLSGVNLP---GVLQQGCVSAKAPVLSGRGKDSVV 1062
Query: 622 WHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPP 655
P PSDS+ P PP ++P P
Sbjct: 1063 EFPSP-PSDSD----------FPPPPPETELPLP 1085
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
[Homo sapiens]
Length = 2191
Score = 70.1 bits (170), Expect = 7e-12
Identities = 103/424 (24%), Positives = 138/424 (32%), Gaps = 63/424 (14%)
Query: 256 QSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQ 315
Q S PP P + EDD +P K G +HP
Sbjct: 100 QHGGAKDSAAGGQADPPGPPLLSKPGDEDD-------------APPKMGEPAGGRYEHPG 146
Query: 316 SPAVPPTYPS-GPPPAASALSTTPGNNGVPAPAAPPSA-LGPKASPAPSHNSGTPAP--- 370
A+ P P + P N AAP S G +A P + G +P
Sbjct: 147 LGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMG 206
Query: 371 ---YAQAVAPPAPSGPSTTQPR------------PPSVQP-SGGGGGGSGGGGSSSSSNS 414
A A A AP Q P +P +GGGGGG GGGG S
Sbjct: 207 MMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGG 266
Query: 415 SAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEP-- 472
GG GA + ++ A + A GG SS G S P P
Sbjct: 267 GGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGG 326
Query: 473 -------SAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGP 525
AAA + AGG +G N PS P +SP+P + + P
Sbjct: 327 GGAASLSKAAAGSAAGGFQRFAGQNQ-HPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSP 385
Query: 526 PQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPP 585
+AP P P S +S A A ++G + + L +D+ +A PA A
Sbjct: 386 ----SAP----PPPPSQPQSQAAAAGAAAGGQQAAAGMGL-GKDMGAQYAAASPAWAAAQ 436
Query: 586 LQLSEVNIPLSLGV-------CPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYL 638
+ P + G P+ P+ + + QLY H P S Y
Sbjct: 437 QRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNP---HSQPQQSSPYPGGSYG 493
Query: 639 PRNP 642
P P
Sbjct: 494 PPGP 497
Score = 54.7 bits (130), Expect = 3e-07
Identities = 83/373 (22%), Positives = 128/373 (34%), Gaps = 61/373 (16%)
Query: 236 QALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPP-SPANCTTENSEDDKKRGRSTDS 294
Q +A P+H + + SS P + S +P + A ++ S + S
Sbjct: 596 QPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQS 655
Query: 295 EVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALG 354
+QSP + P H + P P+ P P S + + +G +PA+ P +
Sbjct: 656 NPAQSPFSPHASP-HLSSIPGGPS--------PSPVGSPVGSNQSRSGPISPASIPGSQM 706
Query: 355 PKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRP-----------PSVQPSGGGGGGS 403
P P S + +Q+ P + TQ P PS+ P GG
Sbjct: 707 PPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQM 766
Query: 404 GGGGSSSSSNSSAG---------GGAGKQNGATSYSSV--VADSPAEVALSSSGGNNASS 452
G SS ++S+G G G + +YS V + S + S N
Sbjct: 767 HAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHG 826
Query: 453 QALGPPSG--PHNPPPSTSKEPSAAAPTGAGGVAPGSGNNS--GGPSLLVPLP------- 501
Q P G P PS + + P + P S S GGP + P+P
Sbjct: 827 QGPSQPCGAVPLGRMPSAGMQ-NRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQ 885
Query: 502 ----------VNPPSSPTPSFSDAKAAGALLNGPP------QFSTAPEIKAPEPLSSLKS 545
N S SF +G + + P S+ +AP P S +
Sbjct: 886 EAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAP-PYSMAPA 944
Query: 546 MAERAAISSGIED 558
M +A S G+ D
Sbjct: 945 MVNSSAASVGLAD 957
Score = 37.7 bits (86), Expect = 0.040
Identities = 88/377 (23%), Positives = 127/377 (33%), Gaps = 57/377 (15%)
Query: 234 IPQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANC--TTENSEDDKKRGRS 291
IP + + PP +QS S+ S SP+P T N + + +
Sbjct: 701 IPGSQMPPQPPG---------SQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQ 751
Query: 292 TDSEVSQSPAKNGSKPVHSNQHPQS-------PAVPPTYPSGP---PPAASALSTTPGNN 341
T +S P+ G + QS P + P G PPA S + + +
Sbjct: 752 TGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSG 811
Query: 342 GVPAPAAPPSALGPKASPAPSHNSGTPA----PYAQAVAPPAPSGPSTTQPRPPSVQPSG 397
P P SA PS G P A P P S+ P P + S
Sbjct: 812 --PGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGM--SQ 867
Query: 398 GGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGP 457
GG G G + + + A Q A S S P + G ASS
Sbjct: 868 QGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPG----MNQSGLMASSSPYSQ 923
Query: 458 PSGPHNPPPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSS--PTPSFSDA 515
P + +T P + AP NS S+ + ++P S P P +D
Sbjct: 924 PMNNSSSLMNTQAPPYSMAPAMV---------NSSAASVGLADMMSPGESKLPLPLKADG 974
Query: 516 KAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTL----HLTERDII 571
K G PQ PE K+ + SS + + + +P L +LT +
Sbjct: 975 KE-----EGTPQ----PESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEER 1025
Query: 572 LSSTSAPPASAQPPLQL 588
S S+ PA + PL L
Sbjct: 1026 GSPVSSLPAVGKKPLDL 1042
Score = 36.6 bits (83), Expect = 0.088
Identities = 41/174 (23%), Positives = 56/174 (32%), Gaps = 34/174 (19%)
Query: 381 SGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEV 440
+G QP P QP GG S GG AD P
Sbjct: 85 AGGGAPQPGPDMEQPQHGGAKDSAAGGQ-------------------------ADPPGPP 119
Query: 441 ALSSSGGNNASSQALGPPSGPHNPPPST----SKEPSAAAPTGAGGVA--PGSGNNSGGP 494
LS G + + +G P+G P +++P A P G GG A P N G
Sbjct: 120 LLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSA 179
Query: 495 SLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAE 548
+ P P P F + G ++A AP + L++ E
Sbjct: 180 A---PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHE 230
Score = 30.0 bits (66), Expect = 8.3
Identities = 33/133 (24%), Positives = 51/133 (38%), Gaps = 10/133 (7%)
Query: 204 KDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVATSPPSHSHMEDEIFNQSSSTPTS 263
++D+ Y + Q P Y ++ D +V +H +Q +S
Sbjct: 1410 RNDMPYPYQNRQGPGGPTQAPPYPGMNRTD--DMMVPDQRINHESQWPSHVSQRQPYMSS 1467
Query: 264 TTSSSPI--PPSPANCTTENSEDDKKRGRSTDS-----EVSQSPAKNGSKPVHSNQHPQS 316
+ S PI PP P+ T + + R S S E SP+K+ P Q
Sbjct: 1468 SASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPSMKMQKVM- 1526
Query: 317 PAVPPTYPSGPPP 329
P VP + +GPPP
Sbjct: 1527 PTVPTSQVTGPPP 1539
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
[Homo sapiens]
Length = 2231
Score = 70.1 bits (170), Expect = 7e-12
Identities = 103/424 (24%), Positives = 138/424 (32%), Gaps = 63/424 (14%)
Query: 256 QSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQ 315
Q S PP P + EDD +P K G +HP
Sbjct: 100 QHGGAKDSAAGGQADPPGPPLLSKPGDEDD-------------APPKMGEPAGGRYEHPG 146
Query: 316 SPAVPPTYPS-GPPPAASALSTTPGNNGVPAPAAPPSA-LGPKASPAPSHNSGTPAP--- 370
A+ P P + P N AAP S G +A P + G +P
Sbjct: 147 LGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMG 206
Query: 371 ---YAQAVAPPAPSGPSTTQPR------------PPSVQP-SGGGGGGSGGGGSSSSSNS 414
A A A AP Q P +P +GGGGGG GGGG S
Sbjct: 207 MMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGG 266
Query: 415 SAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEP-- 472
GG GA + ++ A + A GG SS G S P P
Sbjct: 267 GGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGG 326
Query: 473 -------SAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGP 525
AAA + AGG +G N PS P +SP+P + + P
Sbjct: 327 GGAASLSKAAAGSAAGGFQRFAGQNQ-HPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSP 385
Query: 526 PQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPP 585
+AP P P S +S A A ++G + + L +D+ +A PA A
Sbjct: 386 ----SAP----PPPPSQPQSQAAAAGAAAGGQQAAAGMGL-GKDMGAQYAAASPAWAAAQ 436
Query: 586 LQLSEVNIPLSLGV-------CPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYL 638
+ P + G P+ P+ + + QLY H P S Y
Sbjct: 437 QRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNP---HSQPQQSSPYPGGSYG 493
Query: 639 PRNP 642
P P
Sbjct: 494 PPGP 497
Score = 54.7 bits (130), Expect = 3e-07
Identities = 83/373 (22%), Positives = 128/373 (34%), Gaps = 61/373 (16%)
Query: 236 QALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPP-SPANCTTENSEDDKKRGRSTDS 294
Q +A P+H + + SS P + S +P + A ++ S + S
Sbjct: 583 QPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQS 642
Query: 295 EVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALG 354
+QSP + P H + P P+ P P S + + +G +PA+ P +
Sbjct: 643 NPAQSPFSPHASP-HLSSIPGGPS--------PSPVGSPVGSNQSRSGPISPASIPGSQM 693
Query: 355 PKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRP-----------PSVQPSGGGGGGS 403
P P S + +Q+ P + TQ P PS+ P GG
Sbjct: 694 PPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQM 753
Query: 404 GGGGSSSSSNSSAG---------GGAGKQNGATSYSSV--VADSPAEVALSSSGGNNASS 452
G SS ++S+G G G + +YS V + S + S N
Sbjct: 754 HAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHG 813
Query: 453 QALGPPSG--PHNPPPSTSKEPSAAAPTGAGGVAPGSGNNS--GGPSLLVPLP------- 501
Q P G P PS + + P + P S S GGP + P+P
Sbjct: 814 QGPSQPCGAVPLGRMPSAGMQ-NRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQ 872
Query: 502 ----------VNPPSSPTPSFSDAKAAGALLNGPP------QFSTAPEIKAPEPLSSLKS 545
N S SF +G + + P S+ +AP P S +
Sbjct: 873 EAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAP-PYSMAPA 931
Query: 546 MAERAAISSGIED 558
M +A S G+ D
Sbjct: 932 MVNSSAASVGLAD 944
Score = 42.4 bits (98), Expect = 0.002
Identities = 101/401 (25%), Positives = 130/401 (32%), Gaps = 70/401 (17%)
Query: 255 NQSSSTPTSTTS--SSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSP--------AKNG 304
NQS S P S S S +PP P +E+S + +SQSP A
Sbjct: 676 NQSRSGPISPASIPGSQMPPQPPGSQSESS---------SHPALSQSPMPQERGFMAGTQ 726
Query: 305 SKPVHSNQHPQS--PAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKA----- 357
P + PQ P++ P +PS + +S+ +N S GP+
Sbjct: 727 RNPQMAQYGPQQTGPSMSP-HPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRP 785
Query: 358 ---SPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPR---PPSVQPSGGGGGGSGGGGSSSS 411
S PS + P P A G +QP P PS G G SS
Sbjct: 786 PAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSM 845
Query: 412 SNSSAG----GGAGK-----------QNGATSYSSVVADSPAEVALSSSGGNNASSQALG 456
+ SS G GG G Q A + A+S S G N + A
Sbjct: 846 TPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASS 905
Query: 457 PP-SGPHNPPPS---TSKEPSAAAP----TGAGGVAPGSGNNSGGPSLLVPLPVNPPSSP 508
P S P N S T P + AP + A V + G L +PL +
Sbjct: 906 SPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEG 965
Query: 509 TPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTER 568
TP G Q T + P P+S A+ISS H E
Sbjct: 966 TPQPESKSKDSYSSQGISQPPTPGNLPVPSPMS-----PSSASISS--------FHGDES 1012
Query: 569 DIILSSTSAPPASAQPPLQLSEVNIPLSLGVCPLGPVPLTK 609
D I SS P + P S V LG P K
Sbjct: 1013 DSI-SSPGWPKTPSSPKSSSSTTTGEKITKVYELGNEPERK 1052
Score = 36.6 bits (83), Expect = 0.088
Identities = 41/174 (23%), Positives = 56/174 (32%), Gaps = 34/174 (19%)
Query: 381 SGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEV 440
+G QP P QP GG S GG AD P
Sbjct: 85 AGGGAPQPGPDMEQPQHGGAKDSAAGGQ-------------------------ADPPGPP 119
Query: 441 ALSSSGGNNASSQALGPPSGPHNPPPST----SKEPSAAAPTGAGGVA--PGSGNNSGGP 494
LS G + + +G P+G P +++P A P G GG A P N G
Sbjct: 120 LLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSA 179
Query: 495 SLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAE 548
+ P P P F + G ++A AP + L++ E
Sbjct: 180 A---PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHE 230
Score = 30.0 bits (66), Expect = 8.3
Identities = 33/133 (24%), Positives = 51/133 (38%), Gaps = 10/133 (7%)
Query: 204 KDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVATSPPSHSHMEDEIFNQSSSTPTS 263
++D+ Y + Q P Y ++ D +V +H +Q +S
Sbjct: 1450 RNDMPYPYQNRQGPGGPTQAPPYPGMNRTD--DMMVPDQRINHESQWPSHVSQRQPYMSS 1507
Query: 264 TTSSSPI--PPSPANCTTENSEDDKKRGRSTDS-----EVSQSPAKNGSKPVHSNQHPQS 316
+ S PI PP P+ T + + R S S E SP+K+ P Q
Sbjct: 1508 SASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPSMKMQKVM- 1566
Query: 317 PAVPPTYPSGPPP 329
P VP + +GPPP
Sbjct: 1567 PTVPTSQVTGPPP 1579
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
[Homo sapiens]
Length = 2178
Score = 70.1 bits (170), Expect = 7e-12
Identities = 103/424 (24%), Positives = 138/424 (32%), Gaps = 63/424 (14%)
Query: 256 QSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQ 315
Q S PP P + EDD +P K G +HP
Sbjct: 100 QHGGAKDSAAGGQADPPGPPLLSKPGDEDD-------------APPKMGEPAGGRYEHPG 146
Query: 316 SPAVPPTYPS-GPPPAASALSTTPGNNGVPAPAAPPSA-LGPKASPAPSHNSGTPAP--- 370
A+ P P + P N AAP S G +A P + G +P
Sbjct: 147 LGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMG 206
Query: 371 ---YAQAVAPPAPSGPSTTQPR------------PPSVQP-SGGGGGGSGGGGSSSSSNS 414
A A A AP Q P +P +GGGGGG GGGG S
Sbjct: 207 MMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGG 266
Query: 415 SAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEP-- 472
GG GA + ++ A + A GG SS G S P P
Sbjct: 267 GGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGG 326
Query: 473 -------SAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGP 525
AAA + AGG +G N PS P +SP+P + + P
Sbjct: 327 GGAASLSKAAAGSAAGGFQRFAGQNQ-HPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSP 385
Query: 526 PQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPP 585
+AP P P S +S A A ++G + + L +D+ +A PA A
Sbjct: 386 ----SAP----PPPPSQPQSQAAAAGAAAGGQQAAAGMGL-GKDMGAQYAAASPAWAAAQ 436
Query: 586 LQLSEVNIPLSLGV-------CPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYL 638
+ P + G P+ P+ + + QLY H P S Y
Sbjct: 437 QRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNP---HSQPQQSSPYPGGSYG 493
Query: 639 PRNP 642
P P
Sbjct: 494 PPGP 497
Score = 54.7 bits (130), Expect = 3e-07
Identities = 83/373 (22%), Positives = 128/373 (34%), Gaps = 61/373 (16%)
Query: 236 QALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPP-SPANCTTENSEDDKKRGRSTDS 294
Q +A P+H + + SS P + S +P + A ++ S + S
Sbjct: 583 QPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQS 642
Query: 295 EVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALG 354
+QSP + P H + P P+ P P S + + +G +PA+ P +
Sbjct: 643 NPAQSPFSPHASP-HLSSIPGGPS--------PSPVGSPVGSNQSRSGPISPASIPGSQM 693
Query: 355 PKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRP-----------PSVQPSGGGGGGS 403
P P S + +Q+ P + TQ P PS+ P GG
Sbjct: 694 PPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQM 753
Query: 404 GGGGSSSSSNSSAG---------GGAGKQNGATSYSSV--VADSPAEVALSSSGGNNASS 452
G SS ++S+G G G + +YS V + S + S N
Sbjct: 754 HAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHG 813
Query: 453 QALGPPSG--PHNPPPSTSKEPSAAAPTGAGGVAPGSGNNS--GGPSLLVPLP------- 501
Q P G P PS + + P + P S S GGP + P+P
Sbjct: 814 QGPSQPCGAVPLGRMPSAGMQ-NRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQ 872
Query: 502 ----------VNPPSSPTPSFSDAKAAGALLNGPP------QFSTAPEIKAPEPLSSLKS 545
N S SF +G + + P S+ +AP P S +
Sbjct: 873 EAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAP-PYSMAPA 931
Query: 546 MAERAAISSGIED 558
M +A S G+ D
Sbjct: 932 MVNSSAASVGLAD 944
Score = 37.7 bits (86), Expect = 0.040
Identities = 88/377 (23%), Positives = 127/377 (33%), Gaps = 57/377 (15%)
Query: 234 IPQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANC--TTENSEDDKKRGRS 291
IP + + PP +QS S+ S SP+P T N + + +
Sbjct: 688 IPGSQMPPQPPG---------SQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQ 738
Query: 292 TDSEVSQSPAKNGSKPVHSNQHPQS-------PAVPPTYPSGP---PPAASALSTTPGNN 341
T +S P+ G + QS P + P G PPA S + + +
Sbjct: 739 TGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSG 798
Query: 342 GVPAPAAPPSALGPKASPAPSHNSGTPA----PYAQAVAPPAPSGPSTTQPRPPSVQPSG 397
P P SA PS G P A P P S+ P P + S
Sbjct: 799 --PGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGM--SQ 854
Query: 398 GGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGP 457
GG G G + + + A Q A S S P + G ASS
Sbjct: 855 QGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPG----MNQSGLMASSSPYSQ 910
Query: 458 PSGPHNPPPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSS--PTPSFSDA 515
P + +T P + AP NS S+ + ++P S P P +D
Sbjct: 911 PMNNSSSLMNTQAPPYSMAPAMV---------NSSAASVGLADMMSPGESKLPLPLKADG 961
Query: 516 KAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTL----HLTERDII 571
K G PQ PE K+ + SS + + + +P L +LT +
Sbjct: 962 KE-----EGTPQ----PESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEER 1012
Query: 572 LSSTSAPPASAQPPLQL 588
S S+ PA + PL L
Sbjct: 1013 GSPVSSLPAVGKKPLDL 1029
Score = 36.6 bits (83), Expect = 0.088
Identities = 41/174 (23%), Positives = 56/174 (32%), Gaps = 34/174 (19%)
Query: 381 SGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEV 440
+G QP P QP GG S GG AD P
Sbjct: 85 AGGGAPQPGPDMEQPQHGGAKDSAAGGQ-------------------------ADPPGPP 119
Query: 441 ALSSSGGNNASSQALGPPSGPHNPPPST----SKEPSAAAPTGAGGVA--PGSGNNSGGP 494
LS G + + +G P+G P +++P A P G GG A P N G
Sbjct: 120 LLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSA 179
Query: 495 SLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAE 548
+ P P P F + G ++A AP + L++ E
Sbjct: 180 A---PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHE 230
Score = 30.0 bits (66), Expect = 8.3
Identities = 33/133 (24%), Positives = 51/133 (38%), Gaps = 10/133 (7%)
Query: 204 KDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVATSPPSHSHMEDEIFNQSSSTPTS 263
++D+ Y + Q P Y ++ D +V +H +Q +S
Sbjct: 1397 RNDMPYPYQNRQGPGGPTQAPPYPGMNRTD--DMMVPDQRINHESQWPSHVSQRQPYMSS 1454
Query: 264 TTSSSPI--PPSPANCTTENSEDDKKRGRSTDS-----EVSQSPAKNGSKPVHSNQHPQS 316
+ S PI PP P+ T + + R S S E SP+K+ P Q
Sbjct: 1455 SASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPSMKMQKVM- 1513
Query: 317 PAVPPTYPSGPPP 329
P VP + +GPPP
Sbjct: 1514 PTVPTSQVTGPPP 1526
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 69.7 bits (169), Expect = 9e-12
Identities = 101/406 (24%), Positives = 143/406 (35%), Gaps = 47/406 (11%)
Query: 269 PIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPP 328
P+P PA ++ S + RG S S+ +P +G P SP P G
Sbjct: 605 PLPLPPARSPSQESIGARSRG-SGHSQEQPAPQPSGGDP--------SPPQERNLPEGTE 655
Query: 329 PAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQP 388
S+ PG P P G +SPAP G P ++ PPA T P
Sbjct: 656 RPPKLCSSLPGQGPPPYVFMYPQ--GSPSSPAPGPPPGAPWAFSYLAGPPA------TPP 707
Query: 389 RPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSY-------SSVVADSPAEVA 441
PP +P S G + + A G G G+ + S++V SP+
Sbjct: 708 DPP--RPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTP 765
Query: 442 LSSSGGNNASSQAL-GPPSGPHNPPPSTSKEPSAAAPTGAG-GVAPGSGNNSGGP---SL 496
+ G + S AL GP PPP S +P +PG + GP +L
Sbjct: 766 TPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTL 825
Query: 497 LVPL-PVNPPSSPTP----SFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAERAA 551
P P PP P P S ++ + G P + S+ + E + + A
Sbjct: 826 SEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPA 885
Query: 552 ISSGIEDPVPT---LHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVCPLGPVPLT 608
E PVP +LTE D + P + PLQ + L+ GV P P
Sbjct: 886 GPPPRETPVPPGLDFNLTESDTV---KRRPKCREREPLQTAL----LAFGVASATPGPAA 938
Query: 609 KEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPP 654
A +P P S Q +P P+P +PP
Sbjct: 939 PLPSPTPGESPPA-SSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPP 983
Score = 43.1 bits (100), Expect = 0.001
Identities = 81/310 (26%), Positives = 105/310 (33%), Gaps = 57/310 (18%)
Query: 326 GPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAV-APPAPSGPS 384
GP A L T G+ P A + GP+ P P S P +++ A SG S
Sbjct: 574 GPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARS----PSQESIGARSRGSGHS 629
Query: 385 TTQPRPPSVQPSGGGGG-----GSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAE 439
QP P QPSGG G S+ G G Y SPA
Sbjct: 630 QEQPAP---QPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAP 686
Query: 440 VALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPGS-----GNNSGGP 494
G A S GPP+ P +PP + S + P G A G G+ G
Sbjct: 687 GP--PPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSY 744
Query: 495 SLLVPLP-------VNPPSSPTPS----FSDAKAAGALLNGPPQFSTAPEIKAPEPLSSL 543
+ L P +P +PTP+ S + A A GPP P P L
Sbjct: 745 ATLTRRPGRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPP----------PPPPKRL 794
Query: 544 KSMAERAAISSGI-EDPVPTLHLT-ERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVCP 601
S++ + + E P P T R LS + P PP P
Sbjct: 795 SSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPP--------------AP 840
Query: 602 LGPVPLTKEQ 611
GP T+E+
Sbjct: 841 AGPASDTEEE 850
Score = 43.1 bits (100), Expect = 0.001
Identities = 62/254 (24%), Positives = 80/254 (31%), Gaps = 58/254 (22%)
Query: 266 SSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSP----AKNGSKPVHSNQHPQSPAVPP 321
S P PP+PA ++ E++ + S S A+ G+ + P P PP
Sbjct: 832 SEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGP--PP 889
Query: 322 TYPSGPP----------------------PAASALSTTPGNNGVPAPAAPPSALGPKASP 359
PP P +AL + P PAAP + P SP
Sbjct: 890 RETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPGESP 949
Query: 360 APSHNSGTPAPY---AQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSA 416
P+ + P P AQ V P P+ P PP P S G + + A
Sbjct: 950 -PASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPA 1008
Query: 417 G----GGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEP 472
GAG A P VA + S L P GP PP
Sbjct: 1009 ALLKVPGAG-----------TAPKPVSVACTQLA---FSGPKLAPRLGPRPVPP------ 1048
Query: 473 SAAAPTGAGGVAPG 486
P G V PG
Sbjct: 1049 --PRPESTGTVGPG 1060
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 69.7 bits (169), Expect = 9e-12
Identities = 101/406 (24%), Positives = 143/406 (35%), Gaps = 47/406 (11%)
Query: 269 PIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPP 328
P+P PA ++ S + RG S S+ +P +G P SP P G
Sbjct: 687 PLPLPPARSPSQESIGARSRG-SGHSQEQPAPQPSGGDP--------SPPQERNLPEGTE 737
Query: 329 PAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQP 388
S+ PG P P G +SPAP G P ++ PPA T P
Sbjct: 738 RPPKLCSSLPGQGPPPYVFMYPQ--GSPSSPAPGPPPGAPWAFSYLAGPPA------TPP 789
Query: 389 RPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSY-------SSVVADSPAEVA 441
PP +P S G + + A G G G+ + S++V SP+
Sbjct: 790 DPP--RPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTP 847
Query: 442 LSSSGGNNASSQAL-GPPSGPHNPPPSTSKEPSAAAPTGAG-GVAPGSGNNSGGP---SL 496
+ G + S AL GP PPP S +P +PG + GP +L
Sbjct: 848 TPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTL 907
Query: 497 LVPL-PVNPPSSPTP----SFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAERAA 551
P P PP P P S ++ + G P + S+ + E + + A
Sbjct: 908 SEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPA 967
Query: 552 ISSGIEDPVPT---LHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVCPLGPVPLT 608
E PVP +LTE D + P + PLQ + L+ GV P P
Sbjct: 968 GPPPRETPVPPGLDFNLTESDTV---KRRPKCREREPLQTAL----LAFGVASATPGPAA 1020
Query: 609 KEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPP 654
A +P P S Q +P P+P +PP
Sbjct: 1021 PLPSPTPGESPPA-SSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPP 1065
Score = 43.1 bits (100), Expect = 0.001
Identities = 81/310 (26%), Positives = 105/310 (33%), Gaps = 57/310 (18%)
Query: 326 GPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAV-APPAPSGPS 384
GP A L T G+ P A + GP+ P P S P +++ A SG S
Sbjct: 656 GPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARS----PSQESIGARSRGSGHS 711
Query: 385 TTQPRPPSVQPSGGGGG-----GSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAE 439
QP P QPSGG G S+ G G Y SPA
Sbjct: 712 QEQPAP---QPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAP 768
Query: 440 VALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPGS-----GNNSGGP 494
G A S GPP+ P +PP + S + P G A G G+ G
Sbjct: 769 GP--PPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSY 826
Query: 495 SLLVPLP-------VNPPSSPTPS----FSDAKAAGALLNGPPQFSTAPEIKAPEPLSSL 543
+ L P +P +PTP+ S + A A GPP P P L
Sbjct: 827 ATLTRRPGRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPP----------PPPPKRL 876
Query: 544 KSMAERAAISSGI-EDPVPTLHLT-ERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVCP 601
S++ + + E P P T R LS + P PP P
Sbjct: 877 SSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPP--------------AP 922
Query: 602 LGPVPLTKEQ 611
GP T+E+
Sbjct: 923 AGPASDTEEE 932
Score = 43.1 bits (100), Expect = 0.001
Identities = 62/254 (24%), Positives = 80/254 (31%), Gaps = 58/254 (22%)
Query: 266 SSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSP----AKNGSKPVHSNQHPQSPAVPP 321
S P PP+PA ++ E++ + S S A+ G+ + P P PP
Sbjct: 914 SEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGP--PP 971
Query: 322 TYPSGPP----------------------PAASALSTTPGNNGVPAPAAPPSALGPKASP 359
PP P +AL + P PAAP + P SP
Sbjct: 972 RETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPGESP 1031
Query: 360 APSHNSGTPAPY---AQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSA 416
P+ + P P AQ V P P+ P PP P S G + + A
Sbjct: 1032 -PASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPA 1090
Query: 417 G----GGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEP 472
GAG A P VA + S L P GP PP
Sbjct: 1091 ALLKVPGAG-----------TAPKPVSVACTQLA---FSGPKLAPRLGPRPVPP------ 1130
Query: 473 SAAAPTGAGGVAPG 486
P G V PG
Sbjct: 1131 --PRPESTGTVGPG 1142
>gi|119395716 forkhead box C1 [Homo sapiens]
Length = 553
Score = 68.9 bits (167), Expect = 2e-11
Identities = 74/248 (29%), Positives = 92/248 (37%), Gaps = 22/248 (8%)
Query: 256 QSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHS--NQH 313
Q T T S P P SPA S + S DS S S +GS P S +
Sbjct: 224 QDIKTENGTCPSPPQPLSPAAALGSGSAAAVPKIESPDS--SSSSLSSGSSPPGSLPSAR 281
Query: 314 PQS-----PAVPPTYPSGPPP----AASALSTTPGNNGVPAPAAPPSALGPKASPAPSHN 364
P S A PP PS PPP S + G P AA + G AS A S
Sbjct: 282 PLSLDGADSAPPPPAPSAPPPHHSQGFSVDNIMTSLRGSPQSAAAELSSGLLASAAASSR 341
Query: 365 SGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQN 424
+G P A P S ++ S S GGGGG G + GGAG +
Sbjct: 342 AGIAPPLALGAYSPGQSSLYSSPCSQTSSAGSSGGGGGGAGA-------AGGAGGAGTYH 394
Query: 425 GATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGAGGVA 484
S+ A L + G A A+ P ++ PP TS S+ + G GG
Sbjct: 395 CNLQAMSLYAAGERGGHLQGAPG-GAGGSAVDDPLPDYSLPPVTSSSSSSLSHGGGGG-G 452
Query: 485 PGSGNNSG 492
G G +G
Sbjct: 453 GGGGQEAG 460
Score = 42.7 bits (99), Expect = 0.001
Identities = 74/280 (26%), Positives = 92/280 (32%), Gaps = 67/280 (23%)
Query: 277 CTTENSEDDKKRGRS---TDSEVSQSPAKNGSKPVHSNQHPQSPAVPPT------YPSGP 327
C + DDKK G+ T S + +NGS + + AV + P
Sbjct: 135 CFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAVKDKEEKDRLHLKEP 194
Query: 328 PPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQ 387
PP PG PAP P A G P P P Q + + PS Q
Sbjct: 195 PP--------PGRQPPPAP--PEQADGNAPGPQP------PPVRIQDIKTENGTCPSPPQ 238
Query: 388 PRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGG 447
P P+ G S SS+SS G SS P+ LS G
Sbjct: 239 PLSPAAALGSGSAAAVPKIESPDSSSSSLSSG----------SSPPGSLPSARPLSLDGA 288
Query: 448 NNASSQALGPPSGPHNPPPSTSK--------------EPSAAAPTGAG-----------G 482
++A PP P PPP S+ SAAA +G G
Sbjct: 289 DSAP-----PPPAPSAPPPHHSQGFSVDNIMTSLRGSPQSAAAELSSGLLASAAASSRAG 343
Query: 483 VAP--GSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGA 520
+AP G S G S L P + SS S AGA
Sbjct: 344 IAPPLALGAYSPGQSSLYSSPCSQTSSAGSSGGGGGGAGA 383
Score = 42.7 bits (99), Expect = 0.001
Identities = 49/197 (24%), Positives = 71/197 (36%), Gaps = 25/197 (12%)
Query: 315 QSPAVPPTYPSG-----PPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPA 369
Q P PP G PP N P+P P SPA + SG+ A
Sbjct: 200 QPPPAPPEQADGNAPGPQPPPVRIQDIKTENGTCPSPPQP-------LSPAAALGSGSAA 252
Query: 370 PYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSA-----GGGAGKQN 424
+ +P + S ++ PP PS G + SA G N
Sbjct: 253 AVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDGADSAPPPPAPSAPPPHHSQGFSVDN 312
Query: 425 GATSYSSVVADSPAEVALSSSGGNNASSQA-LGPPS--GPHNPPPST-----SKEPSAAA 476
TS + AE++ ASS+A + PP G ++P S+ + S+A
Sbjct: 313 IMTSLRGSPQSAAAELSSGLLASAAASSRAGIAPPLALGAYSPGQSSLYSSPCSQTSSAG 372
Query: 477 PTGAGGVAPGSGNNSGG 493
+G GG G+ +GG
Sbjct: 373 SSGGGGGGAGAAGGAGG 389
Score = 33.9 bits (76), Expect = 0.57
Identities = 33/123 (26%), Positives = 50/123 (40%), Gaps = 16/123 (13%)
Query: 465 PPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNG 524
PP ++P A P A G APG P + + + P+P + AA G
Sbjct: 194 PPPPGRQPPPAPPEQADGNAPGP---QPPPVRIQDIKTENGTCPSPPQPLSPAAAL---G 247
Query: 525 PPQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDP--VPTLHLTERDIILSSTSAPPASA 582
+ P+I++P+ SS ++SSG P +P+ D S+ P SA
Sbjct: 248 SGSAAAVPKIESPDSSSS--------SLSSGSSPPGSLPSARPLSLDGADSAPPPPAPSA 299
Query: 583 QPP 585
PP
Sbjct: 300 PPP 302
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 68.2 bits (165), Expect = 3e-11
Identities = 93/420 (22%), Positives = 142/420 (33%), Gaps = 59/420 (14%)
Query: 247 SHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSK 306
S E + ++S+ + TS P+P TT K +T E + + K +
Sbjct: 172 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTT-----KGPALTTPKEPTPTTPKEPAS 226
Query: 307 PVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSG 366
P + PT P P P + + T P P+ PK PAP+ +
Sbjct: 227 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK-EPAPT-TTK 284
Query: 367 TPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGA 426
PAP AP P P+ T P+ P+ K+
Sbjct: 285 EPAPTTTKSAPTTPKEPAPTTPKKPAPT-------------------------TPKEPAP 319
Query: 427 TSYSSVVADSPAEVALSSSGGNNASSQALGP-PSGPHNPPPSTSKEPSAAAPTGAGGVAP 485
T+ +P E A ++ A + P P+ P P P+T KEP APT AP
Sbjct: 320 TTPKEPTPTTPKEPAPTTK--EPAPTTPKEPAPTAPKKPAPTTPKEP---APTTPKEPAP 374
Query: 486 GSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLK- 544
+ + P P S+PT + A P+ + K P P + +
Sbjct: 375 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 434
Query: 545 -SMAERAAISSGIEDPVPTLHLTERDIILSSTSAP-------PASAQP-------PLQLS 589
+ + ++P PT T ++ ++T P PA P P +L+
Sbjct: 435 APTTPKKPAPTTPKEPAPT---TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 491
Query: 590 EVNIPLSLGVCPLGPVPLTKEQLYQQAMEE--AAWHHMPHPSDSERIRQYLPRNPCPTPP 647
P P P T E+L EE P P+ + P+ P PT P
Sbjct: 492 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 551
Score = 64.7 bits (156), Expect = 3e-10
Identities = 97/437 (22%), Positives = 151/437 (34%), Gaps = 59/437 (13%)
Query: 261 PTSTTSSSPIPPSPANCTT----ENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQS 316
P TT P P +P T E + K+ +T E + + K + P +
Sbjct: 309 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 368
Query: 317 PAVP---------PTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGT 367
P P PT P P P + + P PAP SA P+P+ +
Sbjct: 369 PKEPAPTTTKEPSPTTPKEPAPTTT--KSAPTTTKEPAPTTTKSAPTTPKEPSPT-TTKE 425
Query: 368 PAPYA-QAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGA 426
PAP + AP P P+ T P+ P+ + + ++ A K+
Sbjct: 426 PAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA-PTTPKETAP 484
Query: 427 TSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPG 486
T+ + +P ++A ++ ++ P+ P P P+T +EP APT AP
Sbjct: 485 TTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP---APTTPKAAAPN 541
Query: 487 SGNNSGGPSLLVPLPVNP-------PSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEP 539
+ + P P P P P+ A L P T P+ AP+
Sbjct: 542 TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP---TTPKKPAPKE 598
Query: 540 LSSLKSMAERAAISSGIEDPVPTLHL----TERDIILSSTSAPPASAQP----PLQLSE- 590
L+ + + S+ + P PT T +T PA P P L E
Sbjct: 599 LAPTTT---KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP 655
Query: 591 ----VNIPLSLGVCPL---GPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPC 643
P + P GP T ++ +E A P+ + P+ P
Sbjct: 656 APTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA------PTTPKEPAPTTPKKPA 709
Query: 644 PTPPYHHQMPPPHSDTV 660
PT P + PPP + V
Sbjct: 710 PTTP---ETPPPTTSEV 723
Score = 56.6 bits (135), Expect = 8e-08
Identities = 73/317 (23%), Positives = 111/317 (35%), Gaps = 55/317 (17%)
Query: 235 PQALVATSPPSHSHME-DEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTD 293
P+ L T+P + +E+ + PT TT P P +P K +T
Sbjct: 495 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP-----------KAAAPNTP 543
Query: 294 SEVSQSPAKNGSKPVHSNQHPQSPA-VPPTYPSGPPPAASALSTTPGNNGVPAPAAP--- 349
E + + K + P +P PT P G T P PAP P
Sbjct: 544 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG---------TAPTTLKEPAPTTPKKP 594
Query: 350 -PSALGPKASPAP-SHNSGTPAPYA-QAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGG 406
P L P + P S PAP + AP P P+ T P+ P
Sbjct: 595 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEP--------------- 639
Query: 407 GSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPP 466
+ ++ G A + ++ +P E+A +++ G +++ P+ P P
Sbjct: 640 -----APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 694
Query: 467 STSKEPSAA-----APTGAGGVAPGSGNNSGGPSLLVPLPVN-PPSSPTPSFSDAKAAGA 520
+T KEP+ APT P + S + P ++ P TP S A
Sbjct: 695 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 754
Query: 521 LLNGPPQFSTAPEIKAP 537
L N P + P K P
Sbjct: 755 LENSPKE-PGVPTTKTP 770
Score = 55.8 bits (133), Expect = 1e-07
Identities = 87/427 (20%), Positives = 143/427 (33%), Gaps = 68/427 (15%)
Query: 255 NQSSSTPTSTTSSSPIPPSPANCTTENSEDDKK-RGRSTDSEVSQSPAKNGSKPVHSNQH 313
N +S TS T + TT N + + ++T ++ +QS K +K +
Sbjct: 133 NSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA---- 188
Query: 314 PQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGT----PA 369
P S + P TTP P P S + +P ++ T PA
Sbjct: 189 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 248
Query: 370 PYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSY 429
P AP P P+ T + P+ P+ + + + + K+ T+
Sbjct: 249 PTTTKSAPTTPKEPAPTTTKEPA--PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 306
Query: 430 SSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAA----APTGAGGVAP 485
+P E A P+ P P P+T KEP+ APT AP
Sbjct: 307 KKPAPTTPKEPA----------------PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP 350
Query: 486 GSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKS 545
+ + P P P P P+ + + T P+ AP S +
Sbjct: 351 TAPKKPAPTTPKEPAPTTP-KEPAPTTTKEPSP-----------TTPKEPAPTTTKSAPT 398
Query: 546 MAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVCPLGPV 605
+ +P PT ++ SAP +P ++ P + P P
Sbjct: 399 TTK---------EPAPT----------TTKSAPTTPKEPSPTTTKEPAPTT----PKEPA 435
Query: 606 PLTKEQLYQQAMEEAA--WHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDTVEFY 663
P T ++ +E A P P+ +++ P+ P PT P P T
Sbjct: 436 PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 495
Query: 664 QRLSTET 670
++L+ T
Sbjct: 496 EKLAPTT 502
Score = 50.8 bits (120), Expect = 5e-06
Identities = 76/360 (21%), Positives = 116/360 (32%), Gaps = 49/360 (13%)
Query: 235 PQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDS 294
P+ L T+P + E + +TP + ++P P+P K+ +T
Sbjct: 511 PEELAPTTPEEPTPTTPE--EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 568
Query: 295 EVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAP----- 349
E + + K + P +P P P STT PAP P
Sbjct: 569 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK---PAPTTPKGTAP 625
Query: 350 -----PSALGPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSG 404
P+ PK PAP+ GT + AP P P+ + P + +
Sbjct: 626 TTPKEPAPTTPK-EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK---------- 674
Query: 405 GGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNP 464
G +S+++ K+ T+ +P + A P+ P P
Sbjct: 675 --GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA----------------PTTPETP 716
Query: 465 PPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSP-TPSFSDAKAAGALLN 523
PP+TS E S T S + S P P +SP P K A
Sbjct: 717 PPTTS-EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAAT-- 773
Query: 524 GPPQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQ 583
P+ +T + K E AA E T TE I ++T + Q
Sbjct: 774 -KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 832
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 68.2 bits (165), Expect = 3e-11
Identities = 93/420 (22%), Positives = 142/420 (33%), Gaps = 59/420 (14%)
Query: 247 SHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSK 306
S E + ++S+ + TS P+P TT K +T E + + K +
Sbjct: 213 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTT-----KGPALTTPKEPTPTTPKEPAS 267
Query: 307 PVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSG 366
P + PT P P P + + T P P+ PK PAP+ +
Sbjct: 268 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK-EPAPT-TTK 325
Query: 367 TPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGA 426
PAP AP P P+ T P+ P+ K+
Sbjct: 326 EPAPTTTKSAPTTPKEPAPTTPKKPAPT-------------------------TPKEPAP 360
Query: 427 TSYSSVVADSPAEVALSSSGGNNASSQALGP-PSGPHNPPPSTSKEPSAAAPTGAGGVAP 485
T+ +P E A ++ A + P P+ P P P+T KEP APT AP
Sbjct: 361 TTPKEPTPTTPKEPAPTTK--EPAPTTPKEPAPTAPKKPAPTTPKEP---APTTPKEPAP 415
Query: 486 GSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLK- 544
+ + P P S+PT + A P+ + K P P + +
Sbjct: 416 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 475
Query: 545 -SMAERAAISSGIEDPVPTLHLTERDIILSSTSAP-------PASAQP-------PLQLS 589
+ + ++P PT T ++ ++T P PA P P +L+
Sbjct: 476 APTTPKKPAPTTPKEPAPT---TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 532
Query: 590 EVNIPLSLGVCPLGPVPLTKEQLYQQAMEE--AAWHHMPHPSDSERIRQYLPRNPCPTPP 647
P P P T E+L EE P P+ + P+ P PT P
Sbjct: 533 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 592
Score = 64.7 bits (156), Expect = 3e-10
Identities = 97/437 (22%), Positives = 151/437 (34%), Gaps = 59/437 (13%)
Query: 261 PTSTTSSSPIPPSPANCTT----ENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQS 316
P TT P P +P T E + K+ +T E + + K + P +
Sbjct: 350 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 409
Query: 317 PAVP---------PTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGT 367
P P PT P P P + + P PAP SA P+P+ +
Sbjct: 410 PKEPAPTTTKEPSPTTPKEPAPTTT--KSAPTTTKEPAPTTTKSAPTTPKEPSPT-TTKE 466
Query: 368 PAPYA-QAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGA 426
PAP + AP P P+ T P+ P+ + + ++ A K+
Sbjct: 467 PAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA-PTTPKETAP 525
Query: 427 TSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPG 486
T+ + +P ++A ++ ++ P+ P P P+T +EP APT AP
Sbjct: 526 TTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP---APTTPKAAAPN 582
Query: 487 SGNNSGGPSLLVPLPVNP-------PSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEP 539
+ + P P P P P+ A L P T P+ AP+
Sbjct: 583 TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP---TTPKKPAPKE 639
Query: 540 LSSLKSMAERAAISSGIEDPVPTLHL----TERDIILSSTSAPPASAQP----PLQLSE- 590
L+ + + S+ + P PT T +T PA P P L E
Sbjct: 640 LAPTTT---KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP 696
Query: 591 ----VNIPLSLGVCPL---GPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPC 643
P + P GP T ++ +E A P+ + P+ P
Sbjct: 697 APTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA------PTTPKEPAPTTPKKPA 750
Query: 644 PTPPYHHQMPPPHSDTV 660
PT P + PPP + V
Sbjct: 751 PTTP---ETPPPTTSEV 764
Score = 56.6 bits (135), Expect = 8e-08
Identities = 73/317 (23%), Positives = 111/317 (35%), Gaps = 55/317 (17%)
Query: 235 PQALVATSPPSHSHME-DEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTD 293
P+ L T+P + +E+ + PT TT P P +P K +T
Sbjct: 536 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP-----------KAAAPNTP 584
Query: 294 SEVSQSPAKNGSKPVHSNQHPQSPA-VPPTYPSGPPPAASALSTTPGNNGVPAPAAP--- 349
E + + K + P +P PT P G T P PAP P
Sbjct: 585 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG---------TAPTTLKEPAPTTPKKP 635
Query: 350 -PSALGPKASPAP-SHNSGTPAPYA-QAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGG 406
P L P + P S PAP + AP P P+ T P+ P
Sbjct: 636 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEP--------------- 680
Query: 407 GSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPP 466
+ ++ G A + ++ +P E+A +++ G +++ P+ P P
Sbjct: 681 -----APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 735
Query: 467 STSKEPSAA-----APTGAGGVAPGSGNNSGGPSLLVPLPVN-PPSSPTPSFSDAKAAGA 520
+T KEP+ APT P + S + P ++ P TP S A
Sbjct: 736 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 795
Query: 521 LLNGPPQFSTAPEIKAP 537
L N P + P K P
Sbjct: 796 LENSPKE-PGVPTTKTP 811
Score = 55.8 bits (133), Expect = 1e-07
Identities = 87/427 (20%), Positives = 143/427 (33%), Gaps = 68/427 (15%)
Query: 255 NQSSSTPTSTTSSSPIPPSPANCTTENSEDDKK-RGRSTDSEVSQSPAKNGSKPVHSNQH 313
N +S TS T + TT N + + ++T ++ +QS K +K +
Sbjct: 174 NSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA---- 229
Query: 314 PQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGT----PA 369
P S + P TTP P P S + +P ++ T PA
Sbjct: 230 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 289
Query: 370 PYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSY 429
P AP P P+ T + P+ P+ + + + + K+ T+
Sbjct: 290 PTTTKSAPTTPKEPAPTTTKEPA--PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 347
Query: 430 SSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAA----APTGAGGVAP 485
+P E A P+ P P P+T KEP+ APT AP
Sbjct: 348 KKPAPTTPKEPA----------------PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP 391
Query: 486 GSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKS 545
+ + P P P P P+ + + T P+ AP S +
Sbjct: 392 TAPKKPAPTTPKEPAPTTP-KEPAPTTTKEPSP-----------TTPKEPAPTTTKSAPT 439
Query: 546 MAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVCPLGPV 605
+ +P PT ++ SAP +P ++ P + P P
Sbjct: 440 TTK---------EPAPT----------TTKSAPTTPKEPSPTTTKEPAPTT----PKEPA 476
Query: 606 PLTKEQLYQQAMEEAA--WHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDTVEFY 663
P T ++ +E A P P+ +++ P+ P PT P P T
Sbjct: 477 PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 536
Query: 664 QRLSTET 670
++L+ T
Sbjct: 537 EKLAPTT 543
Score = 50.8 bits (120), Expect = 5e-06
Identities = 76/360 (21%), Positives = 116/360 (32%), Gaps = 49/360 (13%)
Query: 235 PQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDS 294
P+ L T+P + E + +TP + ++P P+P K+ +T
Sbjct: 552 PEELAPTTPEEPTPTTPE--EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 609
Query: 295 EVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAP----- 349
E + + K + P +P P P STT PAP P
Sbjct: 610 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK---PAPTTPKGTAP 666
Query: 350 -----PSALGPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSG 404
P+ PK PAP+ GT + AP P P+ + P + +
Sbjct: 667 TTPKEPAPTTPK-EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK---------- 715
Query: 405 GGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNP 464
G +S+++ K+ T+ +P + A P+ P P
Sbjct: 716 --GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA----------------PTTPETP 757
Query: 465 PPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSP-TPSFSDAKAAGALLN 523
PP+TS E S T S + S P P +SP P K A
Sbjct: 758 PPTTS-EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAAT-- 814
Query: 524 GPPQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQ 583
P+ +T + K E AA E T TE I ++T + Q
Sbjct: 815 -KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 873
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 68.2 bits (165), Expect = 3e-11
Identities = 93/420 (22%), Positives = 142/420 (33%), Gaps = 59/420 (14%)
Query: 247 SHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSK 306
S E + ++S+ + TS P+P TT K +T E + + K +
Sbjct: 265 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTT-----KGPALTTPKEPTPTTPKEPAS 319
Query: 307 PVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSG 366
P + PT P P P + + T P P+ PK PAP+ +
Sbjct: 320 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK-EPAPT-TTK 377
Query: 367 TPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGA 426
PAP AP P P+ T P+ P+ K+
Sbjct: 378 EPAPTTTKSAPTTPKEPAPTTPKKPAPT-------------------------TPKEPAP 412
Query: 427 TSYSSVVADSPAEVALSSSGGNNASSQALGP-PSGPHNPPPSTSKEPSAAAPTGAGGVAP 485
T+ +P E A ++ A + P P+ P P P+T KEP APT AP
Sbjct: 413 TTPKEPTPTTPKEPAPTTK--EPAPTTPKEPAPTAPKKPAPTTPKEP---APTTPKEPAP 467
Query: 486 GSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLK- 544
+ + P P S+PT + A P+ + K P P + +
Sbjct: 468 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 527
Query: 545 -SMAERAAISSGIEDPVPTLHLTERDIILSSTSAP-------PASAQP-------PLQLS 589
+ + ++P PT T ++ ++T P PA P P +L+
Sbjct: 528 APTTPKKPAPTTPKEPAPT---TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 584
Query: 590 EVNIPLSLGVCPLGPVPLTKEQLYQQAMEE--AAWHHMPHPSDSERIRQYLPRNPCPTPP 647
P P P T E+L EE P P+ + P+ P PT P
Sbjct: 585 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 644
Score = 64.7 bits (156), Expect = 3e-10
Identities = 97/437 (22%), Positives = 151/437 (34%), Gaps = 59/437 (13%)
Query: 261 PTSTTSSSPIPPSPANCTT----ENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQS 316
P TT P P +P T E + K+ +T E + + K + P +
Sbjct: 402 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 461
Query: 317 PAVP---------PTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGT 367
P P PT P P P + + P PAP SA P+P+ +
Sbjct: 462 PKEPAPTTTKEPSPTTPKEPAPTTT--KSAPTTTKEPAPTTTKSAPTTPKEPSPT-TTKE 518
Query: 368 PAPYA-QAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGA 426
PAP + AP P P+ T P+ P+ + + ++ A K+
Sbjct: 519 PAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA-PTTPKETAP 577
Query: 427 TSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPG 486
T+ + +P ++A ++ ++ P+ P P P+T +EP APT AP
Sbjct: 578 TTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP---APTTPKAAAPN 634
Query: 487 SGNNSGGPSLLVPLPVNP-------PSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEP 539
+ + P P P P P+ A L P T P+ AP+
Sbjct: 635 TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP---TTPKKPAPKE 691
Query: 540 LSSLKSMAERAAISSGIEDPVPTLHL----TERDIILSSTSAPPASAQP----PLQLSE- 590
L+ + + S+ + P PT T +T PA P P L E
Sbjct: 692 LAPTTT---KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP 748
Query: 591 ----VNIPLSLGVCPL---GPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPC 643
P + P GP T ++ +E A P+ + P+ P
Sbjct: 749 APTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA------PTTPKEPAPTTPKKPA 802
Query: 644 PTPPYHHQMPPPHSDTV 660
PT P + PPP + V
Sbjct: 803 PTTP---ETPPPTTSEV 816
Score = 56.6 bits (135), Expect = 8e-08
Identities = 73/317 (23%), Positives = 111/317 (35%), Gaps = 55/317 (17%)
Query: 235 PQALVATSPPSHSHME-DEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTD 293
P+ L T+P + +E+ + PT TT P P +P K +T
Sbjct: 588 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP-----------KAAAPNTP 636
Query: 294 SEVSQSPAKNGSKPVHSNQHPQSPA-VPPTYPSGPPPAASALSTTPGNNGVPAPAAP--- 349
E + + K + P +P PT P G T P PAP P
Sbjct: 637 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG---------TAPTTLKEPAPTTPKKP 687
Query: 350 -PSALGPKASPAP-SHNSGTPAPYA-QAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGG 406
P L P + P S PAP + AP P P+ T P+ P
Sbjct: 688 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEP--------------- 732
Query: 407 GSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPP 466
+ ++ G A + ++ +P E+A +++ G +++ P+ P P
Sbjct: 733 -----APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 787
Query: 467 STSKEPSAA-----APTGAGGVAPGSGNNSGGPSLLVPLPVN-PPSSPTPSFSDAKAAGA 520
+T KEP+ APT P + S + P ++ P TP S A
Sbjct: 788 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 847
Query: 521 LLNGPPQFSTAPEIKAP 537
L N P + P K P
Sbjct: 848 LENSPKE-PGVPTTKTP 863
Score = 55.8 bits (133), Expect = 1e-07
Identities = 87/427 (20%), Positives = 143/427 (33%), Gaps = 68/427 (15%)
Query: 255 NQSSSTPTSTTSSSPIPPSPANCTTENSEDDKK-RGRSTDSEVSQSPAKNGSKPVHSNQH 313
N +S TS T + TT N + + ++T ++ +QS K +K +
Sbjct: 226 NSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA---- 281
Query: 314 PQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGT----PA 369
P S + P TTP P P S + +P ++ T PA
Sbjct: 282 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 341
Query: 370 PYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSY 429
P AP P P+ T + P+ P+ + + + + K+ T+
Sbjct: 342 PTTTKSAPTTPKEPAPTTTKEPA--PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 399
Query: 430 SSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAA----APTGAGGVAP 485
+P E A P+ P P P+T KEP+ APT AP
Sbjct: 400 KKPAPTTPKEPA----------------PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP 443
Query: 486 GSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKS 545
+ + P P P P P+ + + T P+ AP S +
Sbjct: 444 TAPKKPAPTTPKEPAPTTP-KEPAPTTTKEPSP-----------TTPKEPAPTTTKSAPT 491
Query: 546 MAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVCPLGPV 605
+ +P PT ++ SAP +P ++ P + P P
Sbjct: 492 TTK---------EPAPT----------TTKSAPTTPKEPSPTTTKEPAPTT----PKEPA 528
Query: 606 PLTKEQLYQQAMEEAA--WHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDTVEFY 663
P T ++ +E A P P+ +++ P+ P PT P P T
Sbjct: 529 PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 588
Query: 664 QRLSTET 670
++L+ T
Sbjct: 589 EKLAPTT 595
Score = 50.8 bits (120), Expect = 5e-06
Identities = 76/360 (21%), Positives = 116/360 (32%), Gaps = 49/360 (13%)
Query: 235 PQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDS 294
P+ L T+P + E + +TP + ++P P+P K+ +T
Sbjct: 604 PEELAPTTPEEPTPTTPE--EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 661
Query: 295 EVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAP----- 349
E + + K + P +P P P STT PAP P
Sbjct: 662 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK---PAPTTPKGTAP 718
Query: 350 -----PSALGPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSG 404
P+ PK PAP+ GT + AP P P+ + P + +
Sbjct: 719 TTPKEPAPTTPK-EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK---------- 767
Query: 405 GGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNP 464
G +S+++ K+ T+ +P + A P+ P P
Sbjct: 768 --GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA----------------PTTPETP 809
Query: 465 PPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSP-TPSFSDAKAAGALLN 523
PP+TS E S T S + S P P +SP P K A
Sbjct: 810 PPTTS-EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAAT-- 866
Query: 524 GPPQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQ 583
P+ +T + K E AA E T TE I ++T + Q
Sbjct: 867 -KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 925
Score = 50.4 bits (119), Expect = 6e-06
Identities = 89/460 (19%), Positives = 161/460 (35%), Gaps = 86/460 (18%)
Query: 246 HSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGS 305
HS E++ +SSS+ +S++SSS I ++ + + + +K+ + D++ +++ K
Sbjct: 117 HSVSENQ---ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTP 173
Query: 306 KP------------------------VHSNQHPQSPAVPPTYPSGPPPA----------- 330
KP N+ SP + P P P+
Sbjct: 174 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET 233
Query: 331 ---------ASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPAP- 380
TT N + + ++ AP ++ +A P P
Sbjct: 234 SLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPK 293
Query: 381 -----SGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVAD 435
GP+ T P+ P+ P+ S + + + K+ T+ S
Sbjct: 294 AETTTKGPALTTPKEPT--PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS-APT 350
Query: 436 SPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEP----SAAAPTGAGGVAPGSGNNS 491
+P E A ++ P+ P P P+T+KEP + +APT AP +
Sbjct: 351 TPKEPA--------PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 402
Query: 492 GGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGP----PQFSTAPEIKAPEPLSSLKSMA 547
+ P P P PTP+ A P TAP+ AP
Sbjct: 403 APTTPKEPAPTT-PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 461
Query: 548 ERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVCPLGPVPL 607
+ + ++P PT T ++ ++T + P + + P + + P + P P P
Sbjct: 462 PKEPAPTTTKEPSPT---TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT----PKEPSPT 514
Query: 608 TKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPP 647
T ++ +E P P+ ++ P+ P PT P
Sbjct: 515 TTKEPAPTTPKE------PAPTTPKKPAPTTPKEPAPTTP 548
Score = 45.4 bits (106), Expect = 2e-04
Identities = 93/439 (21%), Positives = 146/439 (33%), Gaps = 86/439 (19%)
Query: 241 TSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPS---------PANCTTENSEDDKKRGRS 291
TSPPS + +S T STT SP PP+ T E+S + + S
Sbjct: 70 TSPPSSKKAPPP--SGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS 127
Query: 292 TDSEVSQS-------PAKNGSK--------PVHSNQHPQSPAVPPTYPSGPPPAASALST 336
+ S S S +KN + V N+ ++ P P A S L
Sbjct: 128 SSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDN 187
Query: 337 TPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPAPSGPST--TQPRPPSVQ 394
G+ V P + K S +P + P ++ P + + T T + +V+
Sbjct: 188 --GDFKVTTPDTSTTQHN-KVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE 244
Query: 395 PSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSS----SGGNNA 450
+++++ ++ G K A S+ S ++A +S A
Sbjct: 245 TK----------ETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKA 294
Query: 451 SSQALGPP-SGPHNPPPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPT 509
+ GP + P P P+T KEP++ P P P S+PT
Sbjct: 295 ETTTKGPALTTPKEPTPTTPKEPASTTPK-------------------EPTPTTIKSAPT 335
Query: 510 PSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERD 569
A P+ K P P + ++P PT T+
Sbjct: 336 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP--------------KEPAPT--TTKEP 379
Query: 570 IILSSTSAPPASAQPPLQLSEVNIPLSLGVCPLGPVPLT-KEQLYQQAMEEAAWHHMPHP 628
++ SAP +P + P + P P P T KE E A P P
Sbjct: 380 APTTTKSAPTTPKEPAPTTPKKPAPTT----PKEPAPTTPKEPTPTTPKEPAPTTKEPAP 435
Query: 629 SDSERIRQYLPRNPCPTPP 647
+ + P+ P PT P
Sbjct: 436 TTPKEPAPTAPKKPAPTTP 454
Score = 30.8 bits (68), Expect = 4.8
Identities = 72/349 (20%), Positives = 116/349 (33%), Gaps = 61/349 (17%)
Query: 316 SPAVPPTYPSGPPPAASA---LSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYA 372
+P PP+ PPP+ ++ STT K SP P + T
Sbjct: 68 NPTSPPSSKKAPPPSGASQTIKSTT------------------KRSPKPPNKKKT----K 105
Query: 373 QAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQ-----NGAT 427
+ + + + S S S SS NS+A K+ N
Sbjct: 106 KVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKN 165
Query: 428 SYSSVVADSPAEVALSSSGGNNASSQALGPPSG--PHNPPPSTSKEPSAAAPTGAGGVAP 485
P V + SG +N + P + HN STS + + A P P
Sbjct: 166 RTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHN-KVSTSPKITTAKPINPRPSLP 224
Query: 486 GSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKS 545
+ + S SL V + T + + + +G + ++A E ++ E S+
Sbjct: 225 PNSDTSKETSLTVNKETTVETKETTTTNKQTST----DGKEKTTSAKETQSIEKTSA--- 277
Query: 546 MAERAAISSGIEDPVPTLHLTERDIILSSTSAP-------PASAQP--PLQLSEVNIPLS 596
+ A S + P P T + L++ P PAS P P + + P +
Sbjct: 278 -KDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 336
Query: 597 LGVCPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPT 645
P P P T + E P P+ ++ P+ P PT
Sbjct: 337 ----PKEPAPTTTKSAPTTPKE-------PAPTTTKEPAPTTPKEPAPT 374
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 68.2 bits (165), Expect = 3e-11
Identities = 93/420 (22%), Positives = 142/420 (33%), Gaps = 59/420 (14%)
Query: 247 SHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSK 306
S E + ++S+ + TS P+P TT K +T E + + K +
Sbjct: 306 SAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTT-----KGPALTTPKEPTPTTPKEPAS 360
Query: 307 PVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSG 366
P + PT P P P + + T P P+ PK PAP+ +
Sbjct: 361 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK-EPAPT-TTK 418
Query: 367 TPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGA 426
PAP AP P P+ T P+ P+ K+
Sbjct: 419 EPAPTTTKSAPTTPKEPAPTTPKKPAPT-------------------------TPKEPAP 453
Query: 427 TSYSSVVADSPAEVALSSSGGNNASSQALGP-PSGPHNPPPSTSKEPSAAAPTGAGGVAP 485
T+ +P E A ++ A + P P+ P P P+T KEP APT AP
Sbjct: 454 TTPKEPTPTTPKEPAPTTK--EPAPTTPKEPAPTAPKKPAPTTPKEP---APTTPKEPAP 508
Query: 486 GSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLK- 544
+ + P P S+PT + A P+ + K P P + +
Sbjct: 509 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 568
Query: 545 -SMAERAAISSGIEDPVPTLHLTERDIILSSTSAP-------PASAQP-------PLQLS 589
+ + ++P PT T ++ ++T P PA P P +L+
Sbjct: 569 APTTPKKPAPTTPKEPAPT---TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 625
Query: 590 EVNIPLSLGVCPLGPVPLTKEQLYQQAMEE--AAWHHMPHPSDSERIRQYLPRNPCPTPP 647
P P P T E+L EE P P+ + P+ P PT P
Sbjct: 626 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 685
Score = 64.7 bits (156), Expect = 3e-10
Identities = 97/437 (22%), Positives = 151/437 (34%), Gaps = 59/437 (13%)
Query: 261 PTSTTSSSPIPPSPANCTT----ENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQS 316
P TT P P +P T E + K+ +T E + + K + P +
Sbjct: 443 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 502
Query: 317 PAVP---------PTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGT 367
P P PT P P P + + P PAP SA P+P+ +
Sbjct: 503 PKEPAPTTTKEPSPTTPKEPAPTTT--KSAPTTTKEPAPTTTKSAPTTPKEPSPT-TTKE 559
Query: 368 PAPYA-QAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGA 426
PAP + AP P P+ T P+ P+ + + ++ A K+
Sbjct: 560 PAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA-PTTPKETAP 618
Query: 427 TSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPG 486
T+ + +P ++A ++ ++ P+ P P P+T +EP APT AP
Sbjct: 619 TTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP---APTTPKAAAPN 675
Query: 487 SGNNSGGPSLLVPLPVNP-------PSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEP 539
+ + P P P P P+ A L P T P+ AP+
Sbjct: 676 TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP---TTPKKPAPKE 732
Query: 540 LSSLKSMAERAAISSGIEDPVPTLHL----TERDIILSSTSAPPASAQP----PLQLSE- 590
L+ + + S+ + P PT T +T PA P P L E
Sbjct: 733 LAPTTT---KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP 789
Query: 591 ----VNIPLSLGVCPL---GPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPC 643
P + P GP T ++ +E A P+ + P+ P
Sbjct: 790 APTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETA------PTTPKEPAPTTPKKPA 843
Query: 644 PTPPYHHQMPPPHSDTV 660
PT P + PPP + V
Sbjct: 844 PTTP---ETPPPTTSEV 857
Score = 56.6 bits (135), Expect = 8e-08
Identities = 73/317 (23%), Positives = 111/317 (35%), Gaps = 55/317 (17%)
Query: 235 PQALVATSPPSHSHME-DEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTD 293
P+ L T+P + +E+ + PT TT P P +P K +T
Sbjct: 629 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP-----------KAAAPNTP 677
Query: 294 SEVSQSPAKNGSKPVHSNQHPQSPA-VPPTYPSGPPPAASALSTTPGNNGVPAPAAP--- 349
E + + K + P +P PT P G T P PAP P
Sbjct: 678 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG---------TAPTTLKEPAPTTPKKP 728
Query: 350 -PSALGPKASPAP-SHNSGTPAPYA-QAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGG 406
P L P + P S PAP + AP P P+ T P+ P
Sbjct: 729 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEP--------------- 773
Query: 407 GSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPP 466
+ ++ G A + ++ +P E+A +++ G +++ P+ P P
Sbjct: 774 -----APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 828
Query: 467 STSKEPSAA-----APTGAGGVAPGSGNNSGGPSLLVPLPVN-PPSSPTPSFSDAKAAGA 520
+T KEP+ APT P + S + P ++ P TP S A
Sbjct: 829 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 888
Query: 521 LLNGPPQFSTAPEIKAP 537
L N P + P K P
Sbjct: 889 LENSPKE-PGVPTTKTP 904
Score = 55.8 bits (133), Expect = 1e-07
Identities = 87/427 (20%), Positives = 143/427 (33%), Gaps = 68/427 (15%)
Query: 255 NQSSSTPTSTTSSSPIPPSPANCTTENSEDDKK-RGRSTDSEVSQSPAKNGSKPVHSNQH 313
N +S TS T + TT N + + ++T ++ +QS K +K +
Sbjct: 267 NSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA---- 322
Query: 314 PQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGT----PA 369
P S + P TTP P P S + +P ++ T PA
Sbjct: 323 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 382
Query: 370 PYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSY 429
P AP P P+ T + P+ P+ + + + + K+ T+
Sbjct: 383 PTTTKSAPTTPKEPAPTTTKEPA--PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 440
Query: 430 SSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAA----APTGAGGVAP 485
+P E A P+ P P P+T KEP+ APT AP
Sbjct: 441 KKPAPTTPKEPA----------------PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP 484
Query: 486 GSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKS 545
+ + P P P P P+ + + T P+ AP S +
Sbjct: 485 TAPKKPAPTTPKEPAPTTP-KEPAPTTTKEPSP-----------TTPKEPAPTTTKSAPT 532
Query: 546 MAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVCPLGPV 605
+ +P PT ++ SAP +P ++ P + P P
Sbjct: 533 TTK---------EPAPT----------TTKSAPTTPKEPSPTTTKEPAPTT----PKEPA 569
Query: 606 PLTKEQLYQQAMEEAA--WHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDTVEFY 663
P T ++ +E A P P+ +++ P+ P PT P P T
Sbjct: 570 PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP 629
Query: 664 QRLSTET 670
++L+ T
Sbjct: 630 EKLAPTT 636
Score = 50.8 bits (120), Expect = 5e-06
Identities = 76/360 (21%), Positives = 116/360 (32%), Gaps = 49/360 (13%)
Query: 235 PQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDS 294
P+ L T+P + E + +TP + ++P P+P K+ +T
Sbjct: 645 PEELAPTTPEEPTPTTPE--EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 702
Query: 295 EVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAP----- 349
E + + K + P +P P P STT PAP P
Sbjct: 703 ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK---PAPTTPKGTAP 759
Query: 350 -----PSALGPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSG 404
P+ PK PAP+ GT + AP P P+ + P + +
Sbjct: 760 TTPKEPAPTTPK-EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK---------- 808
Query: 405 GGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNP 464
G +S+++ K+ T+ +P + A P+ P P
Sbjct: 809 --GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA----------------PTTPETP 850
Query: 465 PPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSP-TPSFSDAKAAGALLN 523
PP+TS E S T S + S P P +SP P K A
Sbjct: 851 PPTTS-EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAAT-- 907
Query: 524 GPPQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQ 583
P+ +T + K E AA E T TE I ++T + Q
Sbjct: 908 -KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 966
Score = 50.4 bits (119), Expect = 6e-06
Identities = 89/460 (19%), Positives = 161/460 (35%), Gaps = 86/460 (18%)
Query: 246 HSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGS 305
HS E++ +SSS+ +S++SSS I ++ + + + +K+ + D++ +++ K
Sbjct: 158 HSVSENQ---ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTP 214
Query: 306 KP------------------------VHSNQHPQSPAVPPTYPSGPPPA----------- 330
KP N+ SP + P P P+
Sbjct: 215 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET 274
Query: 331 ---------ASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPAP- 380
TT N + + ++ AP ++ +A P P
Sbjct: 275 SLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPK 334
Query: 381 -----SGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVAD 435
GP+ T P+ P+ P+ S + + + K+ T+ S
Sbjct: 335 AETTTKGPALTTPKEPT--PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS-APT 391
Query: 436 SPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEP----SAAAPTGAGGVAPGSGNNS 491
+P E A ++ P+ P P P+T+KEP + +APT AP +
Sbjct: 392 TPKEPA--------PTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 443
Query: 492 GGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGP----PQFSTAPEIKAPEPLSSLKSMA 547
+ P P P PTP+ A P TAP+ AP
Sbjct: 444 APTTPKEPAPTT-PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 502
Query: 548 ERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVCPLGPVPL 607
+ + ++P PT T ++ ++T + P + + P + + P + P P P
Sbjct: 503 PKEPAPTTTKEPSPT---TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT----PKEPSPT 555
Query: 608 TKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPP 647
T ++ +E P P+ ++ P+ P PT P
Sbjct: 556 TTKEPAPTTPKE------PAPTTPKKPAPTTPKEPAPTTP 589
Score = 45.4 bits (106), Expect = 2e-04
Identities = 93/439 (21%), Positives = 146/439 (33%), Gaps = 86/439 (19%)
Query: 241 TSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPS---------PANCTTENSEDDKKRGRS 291
TSPPS + +S T STT SP PP+ T E+S + + S
Sbjct: 111 TSPPSSKKAPPP--SGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS 168
Query: 292 TDSEVSQS-------PAKNGSK--------PVHSNQHPQSPAVPPTYPSGPPPAASALST 336
+ S S S +KN + V N+ ++ P P A S L
Sbjct: 169 SSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDN 228
Query: 337 TPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPAPSGPST--TQPRPPSVQ 394
G+ V P + K S +P + P ++ P + + T T + +V+
Sbjct: 229 --GDFKVTTPDTSTTQHN-KVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE 285
Query: 395 PSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSS----SGGNNA 450
+++++ ++ G K A S+ S ++A +S A
Sbjct: 286 TK----------ETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKA 335
Query: 451 SSQALGPP-SGPHNPPPSTSKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPT 509
+ GP + P P P+T KEP++ P P P S+PT
Sbjct: 336 ETTTKGPALTTPKEPTPTTPKEPASTTPK-------------------EPTPTTIKSAPT 376
Query: 510 PSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAERAAISSGIEDPVPTLHLTERD 569
A P+ K P P + ++P PT T+
Sbjct: 377 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP--------------KEPAPT--TTKEP 420
Query: 570 IILSSTSAPPASAQPPLQLSEVNIPLSLGVCPLGPVPLT-KEQLYQQAMEEAAWHHMPHP 628
++ SAP +P + P + P P P T KE E A P P
Sbjct: 421 APTTTKSAPTTPKEPAPTTPKKPAPTT----PKEPAPTTPKEPTPTTPKEPAPTTKEPAP 476
Query: 629 SDSERIRQYLPRNPCPTPP 647
+ + P+ P PT P
Sbjct: 477 TTPKEPAPTAPKKPAPTTP 495
Score = 30.8 bits (68), Expect = 4.8
Identities = 72/349 (20%), Positives = 116/349 (33%), Gaps = 61/349 (17%)
Query: 316 SPAVPPTYPSGPPPAASA---LSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYA 372
+P PP+ PPP+ ++ STT K SP P + T
Sbjct: 109 NPTSPPSSKKAPPPSGASQTIKSTT------------------KRSPKPPNKKKT----K 146
Query: 373 QAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQ-----NGAT 427
+ + + + S S S SS NS+A K+ N
Sbjct: 147 KVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKN 206
Query: 428 SYSSVVADSPAEVALSSSGGNNASSQALGPPSG--PHNPPPSTSKEPSAAAPTGAGGVAP 485
P V + SG +N + P + HN STS + + A P P
Sbjct: 207 RTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHN-KVSTSPKITTAKPINPRPSLP 265
Query: 486 GSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKS 545
+ + S SL V + T + + + +G + ++A E ++ E S+
Sbjct: 266 PNSDTSKETSLTVNKETTVETKETTTTNKQTST----DGKEKTTSAKETQSIEKTSA--- 318
Query: 546 MAERAAISSGIEDPVPTLHLTERDIILSSTSAP-------PASAQP--PLQLSEVNIPLS 596
+ A S + P P T + L++ P PAS P P + + P +
Sbjct: 319 -KDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 377
Query: 597 LGVCPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPT 645
P P P T + E P P+ ++ P+ P PT
Sbjct: 378 ----PKEPAPTTTKSAPTTPKE-------PAPTTTKEPAPTTPKEPAPT 415
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 68.2 bits (165), Expect = 3e-11
Identities = 84/319 (26%), Positives = 121/319 (37%), Gaps = 18/319 (5%)
Query: 234 IPQALVATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTD 293
IP+ V PS SH + SS+ + + S S + T+ + K G S+
Sbjct: 1067 IPKGTVMVGKPS-SHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSS 1125
Query: 294 ----SEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAP 349
S S + S+ +S+Q P P G +S+ P G P+
Sbjct: 1126 KLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKP--QGKPSSLMN 1183
Query: 350 PSALGPKASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSS 409
PS P SP+ S G A + P + PS+ P S SG GG G SS
Sbjct: 1184 PSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPIS---SGSGGSHMSGTSSS 1240
Query: 410 SSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTS 469
S SS+G G+ + S + + + + SSSG + +SSQ PS +
Sbjct: 1241 SGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQ--NQHGSSKGKSPSRN 1298
Query: 470 KEPSAAAPTGA---GGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPP 526
K+PS A G V G G G L + V+ SS P S +G G
Sbjct: 1299 KKPSLTAVIDKLKHGVVTSGPG---GEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKR 1355
Query: 527 QFSTAPEIKAPEPLSSLKS 545
+ S + K SS+ S
Sbjct: 1356 EKSDKDKSKVSTSGSSVDS 1374
Score = 60.1 bits (144), Expect = 7e-09
Identities = 72/283 (25%), Positives = 111/283 (39%), Gaps = 17/283 (6%)
Query: 280 ENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPG 339
E ++ K G T + P + SKP ++ P + P A + +P
Sbjct: 966 EKTQKRVKEGNGTSNSTLSGPGLD-SKPGKRSRTPSNDGKSKDKPPKRKKADTE-GKSPS 1023
Query: 340 NNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAP----PAPSGP-STTQPRPPSVQ 394
++ P PP++ G SP + S TP A P P G +P S
Sbjct: 1024 HSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQY 1083
Query: 395 PSGGGGGGSGGGG--SSSSSNSSAGGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASS 452
S G SG S SSS+SS+ +GK + S S + S ++ SS G++ SS
Sbjct: 1084 TSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGS--SSSKLSSSMYSSQGSSGSS 1141
Query: 453 QALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAP-GSGNNSGGPSLLVPLPVNPPSSPTPS 511
Q+ P S + ++ + + + P G ++ PSL P ++P S P
Sbjct: 1142 QSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKP-NISPSHSRPPG 1200
Query: 512 FSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAERAAISS 554
SD A+ P T P KA P+SS + + SS
Sbjct: 1201 GSDKLASPM----KPVPGTPPSSKAKSPISSGSGGSHMSGTSS 1239
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.127 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,292,573
Number of Sequences: 37866
Number of extensions: 2511461
Number of successful extensions: 60061
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 969
Number of HSP's successfully gapped in prelim test: 2838
Number of HSP's that attempted gapping in prelim test: 19035
Number of HSP's gapped (non-prelim): 20168
length of query: 753
length of database: 18,247,518
effective HSP length: 110
effective length of query: 643
effective length of database: 14,082,258
effective search space: 9054891894
effective search space used: 9054891894
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.